C2I25_22890 57d3351f741ce28596b32c6b46fee0fe 331 SUPERFAMILY SSF51735 117 266 2.02E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22890 57d3351f741ce28596b32c6b46fee0fe 331 Pfam PF00107 Zinc-binding dehydrogenase 157 267 5.2E-28 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_22890 57d3351f741ce28596b32c6b46fee0fe 331 Gene3D G3DSA:3.40.50.720 126 296 3.7E-101 T 14-10-2018 C2I25_22890 57d3351f741ce28596b32c6b46fee0fe 331 SUPERFAMILY SSF50129 1 151 5.17E-36 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_22890 57d3351f741ce28596b32c6b46fee0fe 331 Gene3D G3DSA:3.90.180.10 8 325 3.7E-101 T 14-10-2018 C2I25_22890 57d3351f741ce28596b32c6b46fee0fe 331 SMART SM00829 10 327 1.4E-47 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_22890 57d3351f741ce28596b32c6b46fee0fe 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.3E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 304 2.4E-19 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 SUPERFAMILY SSF51735 83 273 1.17E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 Gene3D G3DSA:3.30.70.260 306 389 1.0E-19 T 14-10-2018 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 Gene3D G3DSA:3.40.50.720 12 301 4.8E-75 T 14-10-2018 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 SUPERFAMILY SSF52283 22 105 7.37E-21 T 14-10-2018 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 138 165 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 Gene3D G3DSA:3.40.50.720 84 276 4.8E-75 T 14-10-2018 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 SUPERFAMILY SSF55021 307 389 6.47E-16 T 14-10-2018 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 94 272 5.8E-42 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I25_23465 3981f67ab14fdf4b8003cab7301ce87b 390 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site C2I25_26645 7a4ca57fac6b582bed161d1de217fddb 316 Gene3D G3DSA:3.90.245.10 2 315 2.1E-70 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_26645 7a4ca57fac6b582bed161d1de217fddb 316 SUPERFAMILY SSF53590 3 311 8.24E-76 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_26645 7a4ca57fac6b582bed161d1de217fddb 316 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 304 2.3E-60 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain C2I25_01890 18e335aca69c2f37b45cc66fc633de6a 376 PIRSF PIRSF000390 1 375 7.9E-70 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase C2I25_01890 18e335aca69c2f37b45cc66fc633de6a 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 366 3.0E-67 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase C2I25_01890 18e335aca69c2f37b45cc66fc633de6a 376 SUPERFAMILY SSF53383 17 364 4.38E-61 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_01890 18e335aca69c2f37b45cc66fc633de6a 376 Gene3D G3DSA:3.40.640.10 1 376 4.2E-128 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_08320 3410b0545bb91fb48c1d47fa48b2bfdf 368 Pfam PF03845 Spore germination protein 7 319 3.5E-56 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_08320 3410b0545bb91fb48c1d47fa48b2bfdf 368 Gene3D G3DSA:1.20.1740.10 2 366 1.5E-10 T 14-10-2018 C2I25_08320 3410b0545bb91fb48c1d47fa48b2bfdf 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 360 2.4E-54 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_16025 bfa80125f56d23b16bc6cfe591834d13 159 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 14-10-2018 IPR000614 Free Met sulfoxide reductase conserved site C2I25_16025 bfa80125f56d23b16bc6cfe591834d13 159 SUPERFAMILY SSF55781 11 155 8.18E-46 T 14-10-2018 C2I25_16025 bfa80125f56d23b16bc6cfe591834d13 159 Pfam PF13185 GAF domain 50 154 7.2E-12 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_16025 bfa80125f56d23b16bc6cfe591834d13 159 Gene3D G3DSA:3.30.450.40 3 159 5.1E-67 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 86 8.7E-19 T 14-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 SUPERFAMILY SSF48371 207 372 3.99E-32 T 14-10-2018 IPR016024 Armadillo-type fold C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 Pfam PF13646 HEAT repeats 267 351 2.5E-12 T 14-10-2018 C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 Gene3D G3DSA:3.30.1370.70 1 92 1.5E-27 T 14-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 Pfam PF13769 Virulence factor 107 185 2.2E-28 T 14-10-2018 IPR025989 Virulence factor domain C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 SUPERFAMILY SSF110836 3 88 7.98E-23 T 14-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 Gene3D G3DSA:1.25.10.10 195 374 2.1E-27 T 14-10-2018 IPR011989 Armadillo-like helical C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 SMART SM00932 4 90 3.8E-27 T 14-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 SMART SM00567 E-Z type HEAT repeats 279 308 17.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 SMART SM00567 E-Z type HEAT repeats 248 277 0.32 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I25_00520 07ab6248209bddaac0ec2ae0015b0f0b 375 SMART SM00567 E-Z type HEAT repeats 310 339 1.6E-5 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 5.9E-37 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Gene3D G3DSA:1.10.132.30 660 794 4.5E-59 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 760 5.4E-15 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Gene3D G3DSA:1.10.150.390 1129 1191 3.9E-29 T 14-10-2018 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Pfam PF00623 RNA polymerase Rpb1, domain 2 381 474 2.8E-29 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 385 2.7E-9 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 1.0E-88 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1180 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Pfam PF04998 RNA polymerase Rpb1, domain 5 994 1128 4.6E-14 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 989 1.8E-52 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 SMART SM00663 224 503 1.8E-185 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Gene3D G3DSA:1.10.1790.20 950 1127 1.8E-66 T 14-10-2018 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Gene3D G3DSA:1.10.40.90 363 405 5.6E-23 T 14-10-2018 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Gene3D G3DSA:2.40.50.100 966 1028 1.8E-66 T 14-10-2018 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Gene3D G3DSA:1.10.274.100 479 659 1.6E-47 T 14-10-2018 C2I25_11010 052d573398daf0384d76189004d8becf 1203 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1191 18.721 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11010 052d573398daf0384d76189004d8becf 1203 SUPERFAMILY SSF64484 5 1180 0.0 T 14-10-2018 C2I25_14310 2733b4ed8a7f1b9ca33ef3ade88fd6b7 193 Pfam PF02525 Flavodoxin-like fold 1 187 2.0E-53 T 14-10-2018 IPR003680 Flavodoxin-like fold C2I25_14310 2733b4ed8a7f1b9ca33ef3ade88fd6b7 193 Gene3D G3DSA:3.40.50.360 1 192 1.7E-61 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_14310 2733b4ed8a7f1b9ca33ef3ade88fd6b7 193 SUPERFAMILY SSF52218 1 193 5.7E-60 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_13410 4ac0dd79f7610f1d5aa6a02659049ede 309 Pfam PF02603 HPr Serine kinase N terminus 4 127 1.1E-41 T 14-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 C2I25_13410 4ac0dd79f7610f1d5aa6a02659049ede 309 Gene3D G3DSA:3.40.1390.20 3 129 2.6E-44 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily C2I25_13410 4ac0dd79f7610f1d5aa6a02659049ede 309 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.73 T 14-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 C2I25_13410 4ac0dd79f7610f1d5aa6a02659049ede 309 Gene3D G3DSA:3.40.50.300 130 309 5.4E-76 T 14-10-2018 C2I25_13410 4ac0dd79f7610f1d5aa6a02659049ede 309 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 302 1.5E-120 T 14-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 C2I25_13410 4ac0dd79f7610f1d5aa6a02659049ede 309 SUPERFAMILY SSF53795 132 298 3.02E-42 T 14-10-2018 C2I25_13410 4ac0dd79f7610f1d5aa6a02659049ede 309 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 6.1E-78 T 14-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 C2I25_13410 4ac0dd79f7610f1d5aa6a02659049ede 309 SUPERFAMILY SSF75138 1 131 1.96E-41 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily C2I25_07055 a2fae25abd80876ed578d3ee2b2009ce 244 Gene3D G3DSA:3.40.50.300 1 243 1.5E-80 T 14-10-2018 C2I25_07055 a2fae25abd80876ed578d3ee2b2009ce 244 PIRSF PIRSF039085 1 244 3.0E-117 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 C2I25_07055 a2fae25abd80876ed578d3ee2b2009ce 244 SMART SM00382 26 217 3.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_07055 a2fae25abd80876ed578d3ee2b2009ce 244 Pfam PF00005 ABC transporter 17 169 4.9E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_07055 a2fae25abd80876ed578d3ee2b2009ce 244 SUPERFAMILY SSF52540 1 239 4.9E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07055 a2fae25abd80876ed578d3ee2b2009ce 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_01070 7f8adb5bdc5f42349561b666f958f3df 742 SUPERFAMILY SSF54001 351 664 3.16E-54 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_01070 7f8adb5bdc5f42349561b666f958f3df 742 Pfam PF01841 Transglutaminase-like superfamily 423 547 7.2E-27 T 14-10-2018 IPR002931 Transglutaminase-like C2I25_01070 7f8adb5bdc5f42349561b666f958f3df 742 Pfam PF13559 Domain of unknown function (DUF4129) 657 712 8.6E-6 T 14-10-2018 IPR025403 Domain of unknown function DUF4129 C2I25_01070 7f8adb5bdc5f42349561b666f958f3df 742 SMART SM00460 472 549 1.4E-19 T 14-10-2018 IPR002931 Transglutaminase-like C2I25_01070 7f8adb5bdc5f42349561b666f958f3df 742 Gene3D G3DSA:3.10.620.30 375 559 8.4E-25 T 14-10-2018 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 SUPERFAMILY SSF52425 4 169 3.01E-48 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 Gene3D G3DSA:1.10.579.10 289 475 4.1E-87 T 14-10-2018 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 Pfam PF03441 FAD binding domain of DNA photolyase 271 470 6.0E-90 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 Pfam PF00875 DNA photolyase 6 156 1.1E-41 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 PRINTS PR00147 DNA photolyase signature 136 152 4.9E-22 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 PRINTS PR00147 DNA photolyase signature 340 358 4.9E-22 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 PRINTS PR00147 DNA photolyase signature 320 336 4.9E-22 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 PRINTS PR00147 DNA photolyase signature 379 393 4.9E-22 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 SUPERFAMILY SSF48173 186 474 1.11E-113 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 Gene3D G3DSA:1.25.40.80 127 282 5.8E-75 T 14-10-2018 C2I25_23960 73c0da618b8162f1e82ae8ed437c0c06 476 Gene3D G3DSA:3.40.50.620 6 197 5.8E-75 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_10415 b3f0a2335006a57bd9a833a77ded402e 177 Pfam PF01464 Transglycosylase SLT domain 46 126 9.8E-9 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 C2I25_10415 b3f0a2335006a57bd9a833a77ded402e 177 Gene3D G3DSA:1.10.530.10 30 171 3.0E-10 T 14-10-2018 C2I25_10415 b3f0a2335006a57bd9a833a77ded402e 177 SUPERFAMILY SSF53955 34 145 1.64E-12 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily C2I25_11235 945e588becee45a579692b8b6cb57720 120 TIGRFAM TIGR00526 folB_dom: FolB domain 2 119 2.7E-38 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 C2I25_11235 945e588becee45a579692b8b6cb57720 120 Pfam PF02152 Dihydroneopterin aldolase 4 116 4.8E-36 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 C2I25_11235 945e588becee45a579692b8b6cb57720 120 Gene3D G3DSA:3.30.1130.10 1 120 1.6E-46 T 14-10-2018 C2I25_11235 945e588becee45a579692b8b6cb57720 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 3.4E-42 T 14-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 C2I25_11235 945e588becee45a579692b8b6cb57720 120 SMART SM00905 4 117 4.4E-50 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 C2I25_11235 945e588becee45a579692b8b6cb57720 120 SUPERFAMILY SSF55620 2 119 1.95E-39 T 14-10-2018 C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 SUPERFAMILY SSF54909 69 156 4.29E-18 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 27 53 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 SMART SM00344 9 118 6.0E-38 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 Gene3D G3DSA:1.10.10.10 2 61 1.2E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 1.8E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 1.8E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 1.8E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 1.2E-13 T 14-10-2018 C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 Gene3D G3DSA:3.30.70.920 62 152 8.7E-24 T 14-10-2018 C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 SUPERFAMILY SSF46785 8 69 1.07E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_07185 c903c9ae6af19fd682385f16d58a371d 164 Pfam PF01037 Lrp/AsnC ligand binding domain 79 147 2.6E-19 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I25_22145 c48a978d1534961a5a6770b611839358 478 Gene3D G3DSA:3.40.250.10 379 477 1.1E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_22145 c48a978d1534961a5a6770b611839358 478 SUPERFAMILY SSF52821 364 473 9.95E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_22145 c48a978d1534961a5a6770b611839358 478 Pfam PF00581 Rhodanese-like domain 383 466 1.0E-13 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_22145 c48a978d1534961a5a6770b611839358 478 Pfam PF00581 Rhodanese-like domain 274 341 2.5E-6 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_22145 c48a978d1534961a5a6770b611839358 478 Gene3D G3DSA:3.40.250.10 265 367 6.3E-17 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_22145 c48a978d1534961a5a6770b611839358 478 SMART SM00849 12 199 4.4E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_22145 c48a978d1534961a5a6770b611839358 478 SUPERFAMILY SSF52821 250 354 8.51E-12 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_22145 c48a978d1534961a5a6770b611839358 478 Pfam PF00753 Metallo-beta-lactamase superfamily 13 194 1.9E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_22145 c48a978d1534961a5a6770b611839358 478 SUPERFAMILY SSF56281 5 262 1.82E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_22145 c48a978d1534961a5a6770b611839358 478 Gene3D G3DSA:3.60.15.10 1 262 8.9E-78 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_22145 c48a978d1534961a5a6770b611839358 478 SMART SM00450 375 470 2.6E-18 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_22145 c48a978d1534961a5a6770b611839358 478 SMART SM00450 272 365 7.3 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_04715 944cc4cc34241c3ac30620281673771a 402 Pfam PF00512 His Kinase A (phospho-acceptor) domain 188 248 1.8E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04715 944cc4cc34241c3ac30620281673771a 402 SUPERFAMILY SSF55874 257 398 1.57E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04715 944cc4cc34241c3ac30620281673771a 402 SMART SM00387 294 400 5.5E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04715 944cc4cc34241c3ac30620281673771a 402 SMART SM00388 186 252 1.8E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04715 944cc4cc34241c3ac30620281673771a 402 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 296 398 3.5E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04715 944cc4cc34241c3ac30620281673771a 402 Gene3D G3DSA:1.10.287.130 172 246 5.0E-18 T 14-10-2018 C2I25_04715 944cc4cc34241c3ac30620281673771a 402 SUPERFAMILY SSF47384 182 250 5.3E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_04715 944cc4cc34241c3ac30620281673771a 402 Gene3D G3DSA:3.30.565.10 247 399 2.3E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04715 944cc4cc34241c3ac30620281673771a 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 378 3.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04715 944cc4cc34241c3ac30620281673771a 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 397 3.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04715 944cc4cc34241c3ac30620281673771a 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 359 3.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04715 944cc4cc34241c3ac30620281673771a 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 345 3.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04715 944cc4cc34241c3ac30620281673771a 402 Pfam PF07694 5TMR of 5TMR-LYT 19 164 4.2E-12 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I25_02570 edf97d7f404ca3e13e92b966b3aaa219 150 SUPERFAMILY SSF54593 4 145 6.05E-34 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_02570 edf97d7f404ca3e13e92b966b3aaa219 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 132 1.7E-8 T 14-10-2018 C2I25_02570 edf97d7f404ca3e13e92b966b3aaa219 150 Gene3D G3DSA:3.10.180.10 1 150 1.9E-64 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 5 803 34.026 T 14-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Gene3D G3DSA:1.10.268.10 367 455 2.4E-195 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Gene3D G3DSA:3.90.199.10 30 483 2.4E-195 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 469 3.3E-150 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 SUPERFAMILY SSF101904 498 803 7.19E-91 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Gene3D G3DSA:2.120.10.90 498 807 7.0E-98 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Gene3D G3DSA:3.30.1360.40 234 330 2.4E-195 T 14-10-2018 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 SMART SM00434 9 462 2.8E-259 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 SUPERFAMILY SSF56719 29 483 1.24E-167 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 655 696 1.2E-6 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 607 650 2.9E-6 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 503 517 1.5 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 753 5.0E-5 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 598 8.1E-5 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_21575 8bff9b4fc9bffd72f8fde3eeee6857cb 807 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 6 744 0.0 T 14-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 Pfam PF07694 5TMR of 5TMR-LYT 26 186 3.4E-6 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 SMART SM00388 206 272 3.9E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 416 1.4E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 2.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 2.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 2.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 2.9E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 SUPERFAMILY SSF47384 192 270 2.94E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 270 5.5E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 SMART SM00387 313 417 1.5E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 Gene3D G3DSA:3.30.565.10 266 417 2.9E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 Gene3D G3DSA:1.10.287.130 209 265 5.9E-16 T 14-10-2018 C2I25_21935 d4161697a099644cc778564dbcba5c7d 417 SUPERFAMILY SSF55874 263 417 6.68E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 Pfam PF02910 Fumarate reductase flavoprotein C-term 451 578 4.7E-41 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 Gene3D G3DSA:3.90.700.10 257 366 2.5E-124 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 5 578 3.1E-282 T 14-10-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 Gene3D G3DSA:1.20.58.100 422 538 3.3E-31 T 14-10-2018 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 SUPERFAMILY SSF51905 5 430 1.2E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 PIRSF PIRSF000171 342 575 2.8E-13 T 14-10-2018 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 PIRSF PIRSF000171 1 239 4.2E-18 T 14-10-2018 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 395 410 1.1E-6 T 14-10-2018 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.1E-6 T 14-10-2018 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 38 47 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 SUPERFAMILY SSF46977 442 584 8.76E-46 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 Pfam PF00890 FAD binding domain 5 391 1.8E-87 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 Gene3D G3DSA:3.50.50.60 6 402 2.5E-124 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 SUPERFAMILY SSF56425 230 352 3.14E-31 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.7E-9 T 14-10-2018 C2I25_16740 d9df694d3e617d8ac8f78d42776d656e 597 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 1.7E-9 T 14-10-2018 C2I25_08365 0b861491cc31cc883cb5a6bde61c9d22 297 Gene3D G3DSA:3.40.50.300 41 212 1.3E-32 T 14-10-2018 C2I25_08365 0b861491cc31cc883cb5a6bde61c9d22 297 SMART SM00382 55 201 1.1E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08365 0b861491cc31cc883cb5a6bde61c9d22 297 SUPERFAMILY SSF52540 46 272 2.39E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08365 0b861491cc31cc883cb5a6bde61c9d22 297 Pfam PF07728 AAA domain (dynein-related subfamily) 58 195 1.0E-26 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 C2I25_06240 66d0375bc96d39e5e0b2c3904e39ef8e 517 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 4 79 3.4E-24 T 14-10-2018 IPR010094 Transposase (putative), N-terminal C2I25_06240 66d0375bc96d39e5e0b2c3904e39ef8e 517 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 330 410 6.3E-21 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal C2I25_14050 10148a6df00888a3df150802f5d22075 390 Gene3D G3DSA:3.40.47.10 6 273 1.8E-144 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_14050 10148a6df00888a3df150802f5d22075 390 Gene3D G3DSA:3.40.47.10 127 386 1.8E-144 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_14050 10148a6df00888a3df150802f5d22075 390 PIRSF PIRSF000429 1 390 1.8E-125 T 14-10-2018 IPR002155 Thiolase GO:0016747 C2I25_14050 10148a6df00888a3df150802f5d22075 390 Pfam PF00108 Thiolase, N-terminal domain 5 259 1.6E-69 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I25_14050 10148a6df00888a3df150802f5d22075 390 SUPERFAMILY SSF53901 1 262 4.01E-68 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_14050 10148a6df00888a3df150802f5d22075 390 SUPERFAMILY SSF53901 268 389 3.73E-44 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_14050 10148a6df00888a3df150802f5d22075 390 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 C2I25_14050 10148a6df00888a3df150802f5d22075 390 Pfam PF02803 Thiolase, C-terminal domain 268 388 1.1E-49 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I25_14050 10148a6df00888a3df150802f5d22075 390 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I25_14050 10148a6df00888a3df150802f5d22075 390 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 388 6.0E-135 T 14-10-2018 IPR002155 Thiolase GO:0016747 C2I25_14050 10148a6df00888a3df150802f5d22075 390 ProSitePatterns PS00099 Thiolases active site. 371 384 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I25_06230 9079064efce8169cf52fa2a41224ffed 135 SUPERFAMILY SSF46785 44 123 1.29E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_06230 9079064efce8169cf52fa2a41224ffed 135 Gene3D G3DSA:1.10.10.10 23 134 1.2E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_06230 9079064efce8169cf52fa2a41224ffed 135 Pfam PF03551 Transcriptional regulator PadR-like family 48 116 2.5E-14 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_08075 8fe70296950e0ad63db4460b4d2059ba 313 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 127 280 1.8E-39 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_08075 8fe70296950e0ad63db4460b4d2059ba 313 SMART SM00283 53 308 3.1E-37 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_08075 8fe70296950e0ad63db4460b4d2059ba 313 SUPERFAMILY SSF58104 32 300 6.02E-58 T 14-10-2018 C2I25_08075 8fe70296950e0ad63db4460b4d2059ba 313 Gene3D G3DSA:1.10.287.950 3 312 4.4E-56 T 14-10-2018 C2I25_15805 d6ca653a060e2e32de839c32b3ca2577 311 SMART SM00646 185 304 1.7E-12 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_15805 d6ca653a060e2e32de839c32b3ca2577 311 Gene3D G3DSA:3.40.630.40 102 311 1.1E-45 T 14-10-2018 C2I25_15805 d6ca653a060e2e32de839c32b3ca2577 311 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 105 304 3.4E-43 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_15805 d6ca653a060e2e32de839c32b3ca2577 311 SUPERFAMILY SSF53187 103 306 8.48E-36 T 14-10-2018 C2I25_17590 7db0b7e691aa4271a066a5c5d4aa61e6 46 Pfam PF08970 Sporulation inhibitor A 1 42 1.1E-18 T 14-10-2018 IPR015064 Sporulation inhibitor A C2I25_17590 7db0b7e691aa4271a066a5c5d4aa61e6 46 Gene3D G3DSA:1.10.287.1100 4 37 1.7E-15 T 14-10-2018 IPR036916 Sporulation inhibitor A superfamily C2I25_17590 7db0b7e691aa4271a066a5c5d4aa61e6 46 SUPERFAMILY SSF100985 1 44 2.88E-16 T 14-10-2018 IPR036916 Sporulation inhibitor A superfamily C2I25_04050 5ec723e67dc336eddaec62283b41fa1b 198 Pfam PF07670 Nucleoside recognition 43 150 8.2E-10 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 Gene3D G3DSA:1.10.8.280 680 794 9.7E-12 T 14-10-2018 C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 Gene3D G3DSA:1.20.1580.10 120 150 4.1E-50 T 14-10-2018 C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 Gene3D G3DSA:3.40.50.300 409 536 5.4E-27 T 14-10-2018 C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 SUPERFAMILY SSF52540 10 300 4.97E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 Pfam PF00005 ABC transporter 337 488 7.2E-7 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 Gene3D G3DSA:1.20.1580.10 657 838 9.7E-12 T 14-10-2018 C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 SUPERFAMILY SSF52540 337 534 1.71E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 Gene3D G3DSA:3.40.50.300 8 306 4.1E-50 T 14-10-2018 C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 SMART SM00382 20 318 0.063 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 SMART SM00382 343 538 0.36 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26980 76f63d6d4a24414313e1dc1085bf1e34 1056 Gene3D G3DSA:3.40.50.300 332 405 1.6E-9 T 14-10-2018 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SMART SM00260 528 672 1.5E-28 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Gene3D G3DSA:3.30.565.10 349 535 3.9E-61 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SUPERFAMILY SSF50341 535 672 1.44E-29 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Gene3D G3DSA:1.20.120.160 2 142 2.5E-37 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SUPERFAMILY SSF47384 289 349 3.3E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Gene3D G3DSA:3.30.70.1110 144 226 2.6E-17 T 14-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Pfam PF07194 P2 response regulator binding domain 148 225 1.1E-19 T 14-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SUPERFAMILY SSF55052 147 225 1.28E-18 T 14-10-2018 IPR035891 CheY-binding domain of CheA C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Pfam PF01584 CheW-like domain 541 672 9.1E-24 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Gene3D G3DSA:1.10.287.560 288 348 1.4E-11 T 14-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 4.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 514 4.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 490 4.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 533 4.0E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 535 7.5E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SUPERFAMILY SSF47226 3 124 1.96E-32 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SMART SM00387 393 536 3.1E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SUPERFAMILY SSF55874 350 534 6.68E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Pfam PF01627 Hpt domain 4 103 6.3E-18 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Gene3D G3DSA:2.40.50.180 559 627 4.9E-36 T 14-10-2018 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Gene3D G3DSA:2.30.30.40 536 668 4.9E-36 T 14-10-2018 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SMART SM01231 288 348 2.8E-11 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 SMART SM00073 2 99 9.9E-34 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 C2I25_03215 1497cd1db4dc310fb213174ccdf97ab0 672 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 289 346 5.7E-7 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 Gene3D G3DSA:1.10.730.20 631 918 5.4E-103 T 14-10-2018 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 632 8.6E-224 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 SUPERFAMILY SSF47323 643 917 2.43E-81 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 Gene3D G3DSA:3.40.50.620 24 620 4.2E-267 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 SUPERFAMILY SSF52374 1 639 7.35E-156 T 14-10-2018 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 Pfam PF08264 Anticodon-binding domain of tRNA 676 829 2.2E-31 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 Pfam PF06827 Zinc finger found in FPG and IleRS 885 914 1.1E-7 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 6.8E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 518 531 6.8E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 6.8E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 6.8E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 6.8E-33 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 831 0.0 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 21.205 T 14-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 Gene3D G3DSA:3.90.740.10 193 397 4.2E-267 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I25_20020 04b3500fd015d23ef5a70c1f9c12f6e6 921 SUPERFAMILY SSF50677 202 392 6.7E-65 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I25_06345 84b2147969a9f30c6e7b2f33c6e4a628 974 Pfam PF13514 AAA domain 1 198 2.8E-27 T 14-10-2018 IPR038734 Uncharacterized protein YhaN, AAA domain C2I25_06345 84b2147969a9f30c6e7b2f33c6e4a628 974 Gene3D G3DSA:3.40.50.300 1 266 9.3E-21 T 14-10-2018 C2I25_06345 84b2147969a9f30c6e7b2f33c6e4a628 974 Gene3D G3DSA:3.40.50.300 749 973 9.6E-19 T 14-10-2018 C2I25_06345 84b2147969a9f30c6e7b2f33c6e4a628 974 SUPERFAMILY SSF52540 1 963 5.33E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_04295 f1146c1699e6bf39ebaa51712a8c79fa 378 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 12 369 4.2E-134 T 14-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I25_04295 f1146c1699e6bf39ebaa51712a8c79fa 378 Gene3D G3DSA:3.10.400.10 18 155 7.4E-45 T 14-10-2018 C2I25_04295 f1146c1699e6bf39ebaa51712a8c79fa 378 SUPERFAMILY SSF52374 159 370 3.44E-88 T 14-10-2018 C2I25_04295 f1146c1699e6bf39ebaa51712a8c79fa 378 Gene3D G3DSA:3.40.50.620 160 371 7.5E-98 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_04295 f1146c1699e6bf39ebaa51712a8c79fa 378 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 17 373 50.288 T 14-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 C2I25_04295 f1146c1699e6bf39ebaa51712a8c79fa 378 Pfam PF14306 PUA-like domain 21 149 3.7E-47 T 14-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I25_04295 f1146c1699e6bf39ebaa51712a8c79fa 378 Pfam PF01747 ATP-sulfurylase 159 369 3.0E-95 T 14-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I25_04295 f1146c1699e6bf39ebaa51712a8c79fa 378 SUPERFAMILY SSF88697 9 156 5.47E-46 T 14-10-2018 IPR015947 PUA-like superfamily C2I25_20600 4eda2397629f33af2ee2452d54cc6d2f 303 SUPERFAMILY SSF47413 3 71 9.78E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_20600 4eda2397629f33af2ee2452d54cc6d2f 303 Pfam PF13413 Helix-turn-helix domain 8 68 3.1E-22 T 14-10-2018 C2I25_20600 4eda2397629f33af2ee2452d54cc6d2f 303 SMART SM00530 7 68 0.0093 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_20600 4eda2397629f33af2ee2452d54cc6d2f 303 Gene3D G3DSA:1.10.260.40 1 104 6.9E-31 T 14-10-2018 C2I25_20600 4eda2397629f33af2ee2452d54cc6d2f 303 Pfam PF13464 Domain of unknown function (DUF4115) 217 278 4.3E-9 T 14-10-2018 IPR025194 Domain of unknown function DUF4115 C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 240 421 4.6E-35 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 209 238 3.1E-5 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 322 351 3.1E-5 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 Gene3D G3DSA:1.10.287.950 176 432 9.1E-48 T 14-10-2018 C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 SMART SM00283 195 428 4.8E-22 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 SUPERFAMILY SSF58104 144 426 4.32E-50 T 14-10-2018 C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 SUPERFAMILY SSF46458 16 178 4.8E-36 T 14-10-2018 IPR009050 Globin-like superfamily C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 Gene3D G3DSA:1.10.490.10 24 175 6.9E-36 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 C2I25_12055 4314ad1fdeea920edfe8c8dc87db39d4 433 Pfam PF11563 Protoglobin 32 186 1.0E-37 T 14-10-2018 C2I25_27295 8273dce44008b52561236f47ec926d62 439 Gene3D G3DSA:1.20.1170.10 40 323 9.6E-71 T 14-10-2018 C2I25_27295 8273dce44008b52561236f47ec926d62 439 SUPERFAMILY SSF58100 20 265 1.6E-44 T 14-10-2018 C2I25_27295 8273dce44008b52561236f47ec926d62 439 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 36 206 2.2E-51 T 14-10-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 C2I25_02235 a64c2c7d22f4a62a9ea3e536e0283868 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.647 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 C2I25_02235 a64c2c7d22f4a62a9ea3e536e0283868 103 Pfam PF01906 Putative heavy-metal-binding 1 103 8.7E-38 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 C2I25_02235 a64c2c7d22f4a62a9ea3e536e0283868 103 SUPERFAMILY SSF117782 1 103 1.31E-36 T 14-10-2018 IPR035439 UPF0145 domain superfamily C2I25_02235 a64c2c7d22f4a62a9ea3e536e0283868 103 Gene3D G3DSA:3.30.110.70 1 103 8.1E-44 T 14-10-2018 C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 Gene3D G3DSA:3.50.50.60 25 428 1.3E-95 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 SUPERFAMILY SSF51905 22 481 5.61E-61 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 Gene3D G3DSA:3.90.660.10 4 420 1.3E-95 T 14-10-2018 C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 Pfam PF01593 Flavin containing amine oxidoreductase 33 480 3.1E-79 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 Gene3D G3DSA:1.10.405.10 120 230 1.3E-95 T 14-10-2018 C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 SUPERFAMILY SSF54373 321 431 8.5E-31 T 14-10-2018 C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 PRINTS PR00757 Flavin-containing amine oxidase signature 25 44 2.3E-8 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 PRINTS PR00757 Flavin-containing amine oxidase signature 462 479 2.3E-8 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 PRINTS PR00757 Flavin-containing amine oxidase signature 325 344 2.3E-8 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 C2I25_01525 0bf41a41768345b4426b5346fb4e51d4 482 Gene3D G3DSA:1.10.10.1620 437 482 5.7E-20 T 14-10-2018 C2I25_09625 db929288e0da8d18b20bce284d24038b 348 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 5 347 39.106 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I25_09625 db929288e0da8d18b20bce284d24038b 348 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 34 336 1.0E-116 T 14-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I25_09625 db929288e0da8d18b20bce284d24038b 348 Pfam PF01008 Initiation factor 2 subunit family 47 336 2.1E-84 T 14-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 C2I25_09625 db929288e0da8d18b20bce284d24038b 348 Gene3D G3DSA:1.20.120.420 3 148 1.5E-51 T 14-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I25_09625 db929288e0da8d18b20bce284d24038b 348 Gene3D G3DSA:3.40.50.10470 149 348 4.2E-66 T 14-10-2018 C2I25_09625 db929288e0da8d18b20bce284d24038b 348 SUPERFAMILY SSF100950 7 342 4.74E-121 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_09625 db929288e0da8d18b20bce284d24038b 348 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 1.6E-137 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I25_21820 a2c7a4f4a1647059b7f13b588676e902 477 Gene3D G3DSA:1.20.1730.10 26 477 2.8E-80 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I25_21820 a2c7a4f4a1647059b7f13b588676e902 477 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 158 183 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site C2I25_21820 a2c7a4f4a1647059b7f13b588676e902 477 TIGRFAM TIGR02119 panF: sodium/pantothenate symporter 3 474 2.7E-240 T 14-10-2018 IPR011849 Sodium/pantothenate symporter GO:0015081|GO:0015233|GO:0015887|GO:0016021|GO:0036376 C2I25_21820 a2c7a4f4a1647059b7f13b588676e902 477 Pfam PF00474 Sodium:solute symporter family 39 434 5.7E-98 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_21820 a2c7a4f4a1647059b7f13b588676e902 477 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 39 434 2.8E-89 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_22390 794da2095ea977d7292a2f11d2a8b900 220 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 3 219 9.4E-101 T 14-10-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 C2I25_22390 794da2095ea977d7292a2f11d2a8b900 220 SUPERFAMILY SSF102588 3 218 6.15E-49 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I25_22390 794da2095ea977d7292a2f11d2a8b900 220 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 135 1.3E-29 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 C2I25_22390 794da2095ea977d7292a2f11d2a8b900 220 Gene3D G3DSA:3.40.50.10320 1 215 5.9E-49 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 SUPERFAMILY SSF47384 346 427 8.63E-22 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 SMART SM00387 472 584 6.5E-47 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 SMART SM00388 360 427 2.8E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 SMART SM00304 185 237 3.8E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 Pfam PF16736 Single Cache-like 33 149 5.5E-33 T 14-10-2018 IPR031967 PhoR, single Cache-like domain C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 SUPERFAMILY SSF55874 416 582 1.02E-52 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 360 426 2.6E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 242 360 2.4E-10 T 14-10-2018 IPR000014 PAS domain C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 562 3.0E-21 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 3.0E-21 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 581 3.0E-21 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 3.0E-21 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 Gene3D G3DSA:1.10.8.500 185 233 1.1E-5 T 14-10-2018 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 Gene3D G3DSA:3.30.565.10 428 586 2.1E-50 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 SMART SM00091 244 311 4.2E-7 T 14-10-2018 IPR000014 PAS domain C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 SUPERFAMILY SSF55785 233 352 3.05E-11 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 Pfam PF00989 PAS fold 245 351 1.1E-12 T 14-10-2018 IPR013767 PAS fold GO:0006355 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 SUPERFAMILY SSF158472 188 235 1.7E-7 T 14-10-2018 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 582 5.9E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 Gene3D G3DSA:1.10.287.130 357 427 1.1E-26 T 14-10-2018 C2I25_16365 18e500d741707c12c4ee99dcc1070115 587 Gene3D G3DSA:3.30.450.20 234 356 2.8E-17 T 14-10-2018 C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 Gene3D G3DSA:3.40.50.300 1 241 6.1E-81 T 14-10-2018 C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 SMART SM00382 27 214 6.8E-21 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 Pfam PF00005 ABC transporter 18 164 2.5E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 Pfam PF12857 TOBE-like domain 291 345 7.8E-16 T 14-10-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 3.4E-120 T 14-10-2018 IPR005666 Sulphate transport system permease protein 1 GO:0008272|GO:0015419|GO:0016020|GO:0043190 KEGG: 00920+3.6.3.25 C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 Gene3D G3DSA:2.40.50.100 277 346 7.9E-6 T 14-10-2018 C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 SUPERFAMILY SSF50331 239 351 1.04E-13 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 Gene3D G3DSA:2.40.50.140 242 276 7.9E-6 T 14-10-2018 C2I25_05925 08fd68e84bfa62983cb7fa2c819a3e81 357 SUPERFAMILY SSF52540 3 247 8.83E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 Gene3D G3DSA:1.10.10.60 133 189 1.4E-17 T 14-10-2018 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 136 178 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 166 182 1.2E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 151 166 1.2E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 PIRSF PIRSF000408 3 190 1.6E-85 T 14-10-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 Gene3D G3DSA:1.10.10.60 81 132 1.2E-17 T 14-10-2018 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 Pfam PF02805 Metal binding domain of Ada 12 74 2.6E-30 T 14-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 SUPERFAMILY SSF46689 136 185 4.35E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 SUPERFAMILY SSF46689 83 134 1.25E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 Pfam PF12833 Helix-turn-helix domain 105 183 4.3E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 SUPERFAMILY SSF57884 8 88 2.09E-31 T 14-10-2018 IPR035451 Ada-like domain superfamily C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 SMART SM00342 99 182 3.4E-28 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_20825 baffb3856b24bfc18bb006e6847ec9b6 198 Gene3D G3DSA:3.40.10.10 1 76 3.3E-31 T 14-10-2018 IPR035451 Ada-like domain superfamily C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 SMART SM00984 312 414 1.2E-36 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 290 2.2E-39 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 PIRSF PIRSF000124 1 429 9.8E-158 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 SUPERFAMILY SSF51735 1 189 9.63E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 SUPERFAMILY SSF48179 198 292 7.82E-34 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 SUPERFAMILY SSF52413 301 425 3.66E-29 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 410 3.0E-131 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 PIRSF PIRSF500134 1 432 1.7E-162 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 Gene3D G3DSA:3.40.50.720 1 197 2.6E-67 T 14-10-2018 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 183 1.4E-59 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 Gene3D G3DSA:3.40.50.720 229 440 6.9E-66 T 14-10-2018 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 Gene3D G3DSA:1.20.5.100 198 228 2.6E-19 T 14-10-2018 C2I25_13230 8bc2899b21eb70750171cb13dbdd2a60 441 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 312 413 6.6E-24 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.10 1096 1468 1.3E-156 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:1.10.1200.10 3092 3174 2.1E-23 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF47336 3097 3169 4.06E-17 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.30 2321 2566 3.2E-154 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.30 1278 1523 1.3E-156 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF56801 455 1019 1.26E-173 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.10 3175 3354 1.8E-56 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3129 3144 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SMART SM00823 Phosphopantetheine attachment site 1006 1075 8.7E-7 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SMART SM00823 Phosphopantetheine attachment site 2049 2118 4.4E-11 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SMART SM00823 Phosphopantetheine attachment site 3105 3173 0.0085 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 1097 1274 3.0E-51 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 35 212 2.45E-48 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:1.10.1200.10 996 1081 7.4E-24 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF56801 4074 4635 1.26E-158 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.300.30 4510 4612 3.7E-33 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.300.30 1940 2039 3.3E-34 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.300.30 895 995 1.6E-33 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.300.30 2995 3091 1.2E-32 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 518 925 2.3E-143 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4137 4539 4.6E-127 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2622 3024 4.2E-133 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1580 1969 6.1E-125 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.30 3355 3623 2.8E-65 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 3188 3364 6.0E-38 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.10 34 406 5.4E-152 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4257 4268 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF13193 AMP-binding enzyme C-terminal domain 1953 2024 3.1E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF13193 AMP-binding enzyme C-terminal domain 3008 3079 2.0E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF13193 AMP-binding enzyme C-terminal domain 4523 4594 5.0E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF13193 AMP-binding enzyme C-terminal domain 909 980 1.7E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.30 3843 4092 2.6E-129 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.10 2139 2511 3.2E-154 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.40.50.1820 4615 4948 7.0E-78 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 220 484 9.12E-64 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00501 AMP-binding enzyme 4116 4515 4.6E-99 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00501 AMP-binding enzyme 497 901 1.0E-108 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00501 AMP-binding enzyme 2601 3000 1.5E-102 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00501 AMP-binding enzyme 1559 1945 1.7E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00668 Condensation domain 3657 4096 2.6E-94 T 14-10-2018 IPR001242 Condensation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00668 Condensation domain 2137 2581 4.3E-116 T 14-10-2018 IPR001242 Condensation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00668 Condensation domain 3184 3621 1.7E-84 T 14-10-2018 IPR001242 Condensation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00668 Condensation domain 31 477 2.9E-119 T 14-10-2018 IPR001242 Condensation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00668 Condensation domain 1094 1538 8.7E-118 T 14-10-2018 IPR001242 Condensation domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 3842 4079 1.67E-50 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 3372 3621 6.78E-35 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF47336 1001 1107 8.11E-22 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27405 29757409474498de1f8b21411d3ca110 4960 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2073 2088 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.30 216 459 5.4E-152 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 3654 3857 3.78E-45 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.40.50.12780 1544 1939 5.3E-127 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.40.50.12780 2586 2994 1.3E-137 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.40.50.12780 4101 4509 8.3E-134 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.40.50.12780 488 893 3.1E-146 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF56801 1518 2062 9.29E-153 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 2140 2317 1.45E-50 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00550 Phosphopantetheine attachment site 2051 2114 7.9E-17 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00550 Phosphopantetheine attachment site 3107 3168 3.5E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00550 Phosphopantetheine attachment site 4624 4684 3.7E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00550 Phosphopantetheine attachment site 1008 1070 6.0E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF53474 4692 4942 6.39E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF47336 4616 4687 1.96E-16 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF47336 2043 2150 8.24E-24 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Pfam PF00975 Thioesterase domain 4709 4854 7.1E-28 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1695 1706 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_27405 29757409474498de1f8b21411d3ca110 4960 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3495 3641 1.8E-34 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:3.30.559.10 3661 4027 2.6E-129 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 1282 1545 2.45E-62 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1030 1045 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_27405 29757409474498de1f8b21411d3ca110 4960 ProSitePatterns PS00455 Putative AMP-binding domain signature. 638 649 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_27405 29757409474498de1f8b21411d3ca110 4960 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2742 2753 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF56801 2560 3117 1.96E-157 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 SUPERFAMILY SSF52777 2326 2565 6.34E-60 T 14-10-2018 C2I25_27405 29757409474498de1f8b21411d3ca110 4960 Gene3D G3DSA:1.10.1200.10 2040 2120 7.5E-27 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_18450 2070724f9dc69570eb859a2bcaac8d15 579 SUPERFAMILY SSF52540 2 218 1.41E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18450 2070724f9dc69570eb859a2bcaac8d15 579 SUPERFAMILY SSF52540 4 521 2.67E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18450 2070724f9dc69570eb859a2bcaac8d15 579 PIRSF PIRSF003128 1 571 1.8E-184 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 C2I25_18450 2070724f9dc69570eb859a2bcaac8d15 579 Gene3D G3DSA:3.40.50.300 1 250 2.1E-49 T 14-10-2018 C2I25_18450 2070724f9dc69570eb859a2bcaac8d15 579 Gene3D G3DSA:3.40.50.300 301 567 1.5E-49 T 14-10-2018 C2I25_18450 2070724f9dc69570eb859a2bcaac8d15 579 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 521 6.0E-15 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal C2I25_18450 2070724f9dc69570eb859a2bcaac8d15 579 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 5.1E-189 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Pfam PF00575 S1 RNA binding domain 620 691 8.9E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 SUPERFAMILY SSF54211 293 489 3.24E-48 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.302 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 SUPERFAMILY SSF50249 621 704 6.38E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 321 4.3E-16 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 SUPERFAMILY SSF54211 8 144 2.83E-50 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 SUPERFAMILY SSF55666 451 549 1.18E-28 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 3.6E-18 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 4.3E-21 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 SUPERFAMILY SSF54791 556 641 4.93E-24 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Gene3D G3DSA:3.30.1370.10 551 622 6.8E-21 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 1.0E-16 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Pfam PF03725 3' exoribonuclease family, domain 2 460 528 2.0E-6 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Gene3D G3DSA:3.30.230.70 234 550 3.6E-118 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Gene3D G3DSA:3.30.230.70 1 230 8.7E-85 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 PIRSF PIRSF005499 2 712 1.3E-302 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Pfam PF00013 KH domain 557 615 1.4E-9 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 692 0.0 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 Gene3D G3DSA:2.40.50.140 623 693 1.0E-26 T 14-10-2018 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 SMART SM00322 553 618 1.4E-12 T 14-10-2018 IPR004087 K Homology domain GO:0003676 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 SUPERFAMILY SSF55666 145 235 6.81E-30 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_20480 ce52247db1a3cf7f2d0984c3aec58965 712 SMART SM00316 621 691 1.7E-25 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 Pfam PF00175 Oxidoreductase NAD-binding domain 269 376 7.9E-18 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 Gene3D G3DSA:3.40.50.80 261 401 6.9E-35 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I25_04165 cd912e96defad571d699fa62d81d829e 402 Gene3D G3DSA:2.40.30.10 149 258 1.2E-38 T 14-10-2018 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 Hamap MF_01252 Flavohemoprotein [hmp]. 1 401 58.634 T 14-10-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 SUPERFAMILY SSF46458 2 141 1.53E-41 T 14-10-2018 IPR009050 Globin-like superfamily C2I25_04165 cd912e96defad571d699fa62d81d829e 402 SUPERFAMILY SSF52343 262 398 1.96E-36 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I25_04165 cd912e96defad571d699fa62d81d829e 402 SUPERFAMILY SSF63380 149 259 2.89E-31 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I25_04165 cd912e96defad571d699fa62d81d829e 402 Gene3D G3DSA:1.10.490.10 1 143 1.5E-55 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 183 195 1.2E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 268 287 1.2E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 363 371 1.2E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 Pfam PF00042 Globin 7 103 2.4E-10 T 14-10-2018 IPR000971 Globin GO:0020037 C2I25_04165 cd912e96defad571d699fa62d81d829e 402 Pfam PF00970 Oxidoreductase FAD-binding domain 156 257 8.2E-10 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 Pfam PF01751 Toprim domain 3 138 1.3E-9 T 14-10-2018 IPR006171 TOPRIM domain C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 710 9.8E-192 T 14-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 Gene3D G3DSA:1.10.460.10 164 596 2.7E-158 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 SUPERFAMILY SSF56712 1 600 8.63E-178 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 SMART SM00493 1 130 4.2E-14 T 14-10-2018 IPR006171 TOPRIM domain C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 1.9E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 1.9E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 514 528 1.9E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 1.9E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 1.9E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 Gene3D G3DSA:2.70.20.10 219 481 2.7E-158 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 310 324 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 SMART SM00436 130 225 4.5E-35 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 Gene3D G3DSA:3.40.50.140 1 158 1.7E-50 T 14-10-2018 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 SMART SM00437 273 551 4.5E-87 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 Pfam PF13342 C-terminal repeat of topoisomerase 656 713 4.9E-17 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 Gene3D G3DSA:1.10.290.10 282 411 2.7E-158 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 C2I25_02135 191fcc7e2dd198951e60dc7318d8ed70 714 Pfam PF01131 DNA topoisomerase 158 586 3.1E-127 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_21065 6eee628dffa9adab7f9f58ae76c0ecc2 267 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 15 267 4.5E-90 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 C2I25_21065 6eee628dffa9adab7f9f58ae76c0ecc2 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 265 2.2E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_21065 6eee628dffa9adab7f9f58ae76c0ecc2 267 SUPERFAMILY SSF161098 71 258 2.49E-38 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_21065 6eee628dffa9adab7f9f58ae76c0ecc2 267 Gene3D G3DSA:1.10.3720.10 70 266 7.9E-37 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 Pfam PF00364 Biotin-requiring enzyme 5 77 1.7E-22 T 14-10-2018 IPR000089 Biotin/lipoyl attachment C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 SUPERFAMILY SSF47005 113 158 8.11E-12 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 209 432 7.8E-79 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 Gene3D G3DSA:3.30.559.10 192 439 9.1E-94 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 SUPERFAMILY SSF52777 210 431 1.78E-80 T 14-10-2018 C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 Pfam PF02817 e3 binding domain 120 154 2.1E-12 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 SUPERFAMILY SSF51230 3 96 1.16E-26 T 14-10-2018 IPR011053 Single hybrid motif C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 Gene3D G3DSA:2.40.50.100 1 103 4.0E-28 T 14-10-2018 C2I25_18610 6a46b24ded630fa2982b1d364f8825d6 439 Gene3D G3DSA:4.10.320.10 112 164 1.0E-14 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I25_27125 9a30dd7f63e92e43965807dda7f14b63 71 Pfam PF00364 Biotin-requiring enzyme 9 70 5.2E-17 T 14-10-2018 IPR000089 Biotin/lipoyl attachment C2I25_27125 9a30dd7f63e92e43965807dda7f14b63 71 SUPERFAMILY SSF51230 3 71 7.46E-22 T 14-10-2018 IPR011053 Single hybrid motif C2I25_27125 9a30dd7f63e92e43965807dda7f14b63 71 Gene3D G3DSA:2.40.50.100 5 71 3.3E-25 T 14-10-2018 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 SUPERFAMILY SSF81301 185 398 4.41E-67 T 14-10-2018 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 Gene3D G3DSA:3.30.460.10 198 330 2.2E-54 T 14-10-2018 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 SMART SM00954 240 350 4.5E-69 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 Pfam PF13291 ACT domain 649 724 1.4E-20 T 14-10-2018 IPR002912 ACT domain C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 SUPERFAMILY SSF109604 10 196 2.86E-77 T 14-10-2018 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 Gene3D G3DSA:3.30.70.260 648 727 1.3E-16 T 14-10-2018 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 SMART SM00471 46 158 1.3E-8 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 Gene3D G3DSA:3.10.20.30 387 459 3.1E-32 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 Gene3D G3DSA:1.10.3210.10 1 196 9.5E-89 T 14-10-2018 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 Pfam PF13328 HD domain 31 180 1.0E-52 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 SUPERFAMILY SSF55021 648 726 9.67E-11 T 14-10-2018 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 Pfam PF02824 TGS domain 394 453 1.8E-21 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 724 3.2E-260 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 SUPERFAMILY SSF81271 381 453 8.01E-23 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 C2I25_17235 6f7d0dc9f0987fe35189880e8790c325 727 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 1.3E-39 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 SUPERFAMILY SSF51445 68 503 3.63E-125 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 Gene3D G3DSA:3.20.20.80 133 499 2.9E-158 T 14-10-2018 C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 SUPERFAMILY SSF51011 507 585 3.42E-19 T 14-10-2018 C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 Gene3D G3DSA:2.60.40.1180 507 586 3.6E-24 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 Pfam PF00128 Alpha amylase, catalytic domain 173 469 1.9E-81 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 Gene3D G3DSA:3.90.400.10 246 299 2.9E-158 T 14-10-2018 C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 Pfam PF16657 Maltogenic Amylase, C-terminal domain 507 583 6.2E-17 T 14-10-2018 IPR032091 Maltogenic Amylase, C-terminal C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 Gene3D G3DSA:2.60.40.10 1 125 1.2E-46 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 121 6.4E-49 T 14-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 C2I25_19410 8a02ccba2e8fb245012d16f5ba6271e3 586 SMART SM00642 139 497 2.9E-123 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_24770 0a8b8fc2d627ac2e5d4293826a7e1b27 178 SUPERFAMILY SSF55729 4 176 1.21E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24770 0a8b8fc2d627ac2e5d4293826a7e1b27 178 Gene3D G3DSA:3.40.630.30 2 178 6.6E-47 T 14-10-2018 C2I25_24770 0a8b8fc2d627ac2e5d4293826a7e1b27 178 Pfam PF13523 Acetyltransferase (GNAT) domain 14 157 2.3E-26 T 14-10-2018 C2I25_14255 2e63e2cfa69c2c5e9322a635fadeee49 257 Pfam PF10086 Putative membrane peptidase family (DUF2324) 17 233 1.4E-78 T 14-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 C2I25_14255 2e63e2cfa69c2c5e9322a635fadeee49 257 PIRSF PIRSF033101 1 257 9.7E-107 T 14-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 SUPERFAMILY SSF46785 1 85 1.27E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 3.7E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 SUPERFAMILY SSF53850 99 292 4.03E-37 T 14-10-2018 C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 Gene3D G3DSA:1.10.10.10 1 87 8.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 Pfam PF03466 LysR substrate binding domain 98 288 1.3E-40 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_13130 11d72f663b5b58f6b39dba83e17f13c5 294 Gene3D G3DSA:3.40.190.290 92 293 1.8E-50 T 14-10-2018 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Gene3D G3DSA:2.60.40.10 765 850 4.7E-25 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Pfam PF00801 PKD domain 793 840 3.4E-11 T 14-10-2018 IPR000601 PKD domain C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 SUPERFAMILY SSF89260 855 964 3.27E-30 T 14-10-2018 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Pfam PF01752 Collagenase 310 632 7.8E-82 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Gene3D G3DSA:2.60.120.380 851 965 2.6E-24 T 14-10-2018 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Gene3D G3DSA:3.30.980.50 655 764 1.0E-47 T 14-10-2018 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 SMART SM00089 771 853 7.0E-18 T 14-10-2018 IPR022409 PKD/Chitinase domain C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Pfam PF08453 Peptidase family M9 N-terminal 94 275 5.1E-53 T 14-10-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 886 951 1.4E-5 T 14-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 SUPERFAMILY SSF49299 733 850 2.49E-18 T 14-10-2018 IPR035986 PKD domain superfamily C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Gene3D G3DSA:1.10.1740.190 373 516 1.5E-59 T 14-10-2018 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 463 479 5.0E-30 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 526 541 5.0E-30 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 446 460 5.0E-30 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 500 518 5.0E-30 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 160 178 5.0E-30 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_08715 f86b21ee60ae1faa8dd8079c5825945f 965 Gene3D G3DSA:1.10.390.20 517 654 1.5E-55 T 14-10-2018 C2I25_04640 ce7ec0f1431684a1cc87f38dd1656eff 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 7.5E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_04640 ce7ec0f1431684a1cc87f38dd1656eff 126 SMART SM00345 15 74 7.6E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_04640 ce7ec0f1431684a1cc87f38dd1656eff 126 Gene3D G3DSA:1.10.10.10 8 126 5.5E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04640 ce7ec0f1431684a1cc87f38dd1656eff 126 SUPERFAMILY SSF46785 4 87 1.37E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Gene3D G3DSA:1.20.1640.10 528 1026 2.7E-275 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 SUPERFAMILY SSF82714 726 810 6.54E-9 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Gene3D G3DSA:3.30.2090.10 177 293 2.7E-275 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Gene3D G3DSA:3.30.70.1440 675 869 2.7E-275 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Gene3D G3DSA:3.30.70.1430 581 674 2.7E-275 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 PRINTS PR00702 Acriflavin resistance protein family signature 489 512 1.5E-48 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 PRINTS PR00702 Acriflavin resistance protein family signature 353 376 1.5E-48 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 PRINTS PR00702 Acriflavin resistance protein family signature 380 401 1.5E-48 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.5E-48 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 PRINTS PR00702 Acriflavin resistance protein family signature 566 583 1.5E-48 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.5E-48 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 PRINTS PR00702 Acriflavin resistance protein family signature 408 432 1.5E-48 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.5E-48 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Gene3D G3DSA:1.20.1640.10 11 527 2.7E-275 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Gene3D G3DSA:3.30.2090.10 724 812 2.7E-275 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 SUPERFAMILY SSF82866 811 1035 8.37E-47 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 SUPERFAMILY SSF82693 134 345 5.58E-17 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Gene3D G3DSA:3.30.70.1320 132 349 2.7E-275 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 SUPERFAMILY SSF82866 314 515 1.57E-43 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Pfam PF00873 AcrB/AcrD/AcrF family 278 1029 4.3E-171 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Pfam PF00873 AcrB/AcrD/AcrF family 4 244 2.9E-43 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 Gene3D G3DSA:3.30.70.1430 41 820 2.7E-275 T 14-10-2018 C2I25_12000 94db07db4d29ad92ae8eb5acec649d77 1038 SUPERFAMILY SSF82693 41 133 2.09E-21 T 14-10-2018 C2I25_25200 e9ea50a1d483b21cda3000e440e5ff33 256 SUPERFAMILY SSF55729 90 254 2.27E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25200 e9ea50a1d483b21cda3000e440e5ff33 256 Gene3D G3DSA:3.40.630.30 116 242 2.1E-44 T 14-10-2018 C2I25_25200 e9ea50a1d483b21cda3000e440e5ff33 256 Pfam PF12746 GNAT acetyltransferase 15 251 3.2E-83 T 14-10-2018 IPR027365 GNAT acetyltransferase YdfB-like C2I25_25200 e9ea50a1d483b21cda3000e440e5ff33 256 Gene3D G3DSA:3.40.630.110 6 115 1.2E-23 T 14-10-2018 C2I25_14230 c9b8b5246cd6367dc809a3dfcb678780 327 Pfam PF01551 Peptidase family M23 203 301 1.8E-19 T 14-10-2018 IPR016047 Peptidase M23 C2I25_14230 c9b8b5246cd6367dc809a3dfcb678780 327 SUPERFAMILY SSF51261 112 314 2.04E-37 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_14230 c9b8b5246cd6367dc809a3dfcb678780 327 Gene3D G3DSA:2.70.70.10 114 326 9.6E-57 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_16595 ce3808c376cb3c8fc15f99d5a218bbf0 327 Pfam PF01032 FecCD transport family 14 320 5.5E-87 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_16595 ce3808c376cb3c8fc15f99d5a218bbf0 327 SUPERFAMILY SSF81345 3 320 1.57E-75 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_16595 ce3808c376cb3c8fc15f99d5a218bbf0 327 Gene3D G3DSA:1.10.3470.10 2 325 8.1E-87 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_08220 eb867f50590f547c4368e065e4fecee5 591 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 109 131 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site C2I25_08220 eb867f50590f547c4368e065e4fecee5 591 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 501 9.2E-89 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_08220 eb867f50590f547c4368e065e4fecee5 591 Gene3D G3DSA:3.40.190.10 29 316 5.2E-55 T 14-10-2018 C2I25_08220 eb867f50590f547c4368e065e4fecee5 591 PIRSF PIRSF002741 4 585 1.7E-94 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_08220 eb867f50590f547c4368e065e4fecee5 591 Gene3D G3DSA:3.10.105.10 317 551 3.0E-81 T 14-10-2018 C2I25_08220 eb867f50590f547c4368e065e4fecee5 591 SUPERFAMILY SSF53850 56 580 7.24E-118 T 14-10-2018 C2I25_17965 2139bbb80c6958780b940ab0cd65ce16 192 SUPERFAMILY SSF100950 4 188 2.09E-50 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_17965 2139bbb80c6958780b940ab0cd65ce16 192 PIRSF PIRSF006806 1 185 3.7E-47 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase C2I25_17965 2139bbb80c6958780b940ab0cd65ce16 192 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 5 182 1.9E-57 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase C2I25_17965 2139bbb80c6958780b940ab0cd65ce16 192 Gene3D G3DSA:3.40.50.10420 1 192 7.1E-74 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily C2I25_17965 2139bbb80c6958780b940ab0cd65ce16 192 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 182 3.5E-44 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase C2I25_11270 313fbb9edaf2203226ddb6513b1cec71 262 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 249 2.3E-87 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 C2I25_11270 313fbb9edaf2203226ddb6513b1cec71 262 Gene3D G3DSA:3.30.420.40 1 88 2.5E-36 T 14-10-2018 C2I25_11270 313fbb9edaf2203226ddb6513b1cec71 262 Pfam PF03309 Type III pantothenate kinase 3 206 4.4E-75 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 C2I25_11270 313fbb9edaf2203226ddb6513b1cec71 262 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 38.173 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 C2I25_11270 313fbb9edaf2203226ddb6513b1cec71 262 SUPERFAMILY SSF53067 124 253 1.44E-41 T 14-10-2018 C2I25_11270 313fbb9edaf2203226ddb6513b1cec71 262 SUPERFAMILY SSF53067 1 122 9.81E-40 T 14-10-2018 C2I25_11270 313fbb9edaf2203226ddb6513b1cec71 262 Gene3D G3DSA:3.30.420.40 89 262 3.9E-65 T 14-10-2018 C2I25_12005 f6dbe03f07b7bcd89f37efa1cadce720 289 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_12005 f6dbe03f07b7bcd89f37efa1cadce720 289 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_12005 f6dbe03f07b7bcd89f37efa1cadce720 289 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_12005 f6dbe03f07b7bcd89f37efa1cadce720 289 SUPERFAMILY SSF46689 3 69 6.16E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_12005 f6dbe03f07b7bcd89f37efa1cadce720 289 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 2.9E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_12005 f6dbe03f07b7bcd89f37efa1cadce720 289 Gene3D G3DSA:1.10.357.10 1 158 3.5E-28 T 14-10-2018 C2I25_16695 af2acb5891bc2752ce0d8b3775223d21 563 Gene3D G3DSA:3.40.50.12780 12 449 8.9E-137 T 14-10-2018 C2I25_16695 af2acb5891bc2752ce0d8b3775223d21 563 Gene3D G3DSA:3.30.300.310 455 559 2.3E-32 T 14-10-2018 C2I25_16695 af2acb5891bc2752ce0d8b3775223d21 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 543 4.3E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_16695 af2acb5891bc2752ce0d8b3775223d21 563 Pfam PF00501 AMP-binding enzyme 31 458 1.6E-120 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_16695 af2acb5891bc2752ce0d8b3775223d21 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_16695 af2acb5891bc2752ce0d8b3775223d21 563 SUPERFAMILY SSF56801 18 553 3.92E-165 T 14-10-2018 C2I25_00550 291c101033d6d92d159429198293cffa 215 SMART SM00471 22 136 1.5E-8 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_00550 291c101033d6d92d159429198293cffa 215 SUPERFAMILY SSF109604 4 213 3.14E-76 T 14-10-2018 C2I25_00550 291c101033d6d92d159429198293cffa 215 Pfam PF01966 HD domain 28 126 2.9E-9 T 14-10-2018 IPR006674 HD domain C2I25_00550 291c101033d6d92d159429198293cffa 215 Gene3D G3DSA:1.10.472.50 1 99 7.9E-37 T 14-10-2018 C2I25_00550 291c101033d6d92d159429198293cffa 215 Gene3D G3DSA:1.20.58.1910 102 215 5.6E-49 T 14-10-2018 C2I25_13180 2edd3021393d48856eb3b04ddaf5d5d8 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 8.5E-23 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I25_13180 2edd3021393d48856eb3b04ddaf5d5d8 100 Gene3D G3DSA:3.40.50.2300 1 100 2.1E-41 T 14-10-2018 C2I25_13180 2edd3021393d48856eb3b04ddaf5d5d8 100 SUPERFAMILY SSF52794 1 99 4.45E-35 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I25_14175 9602d5b2a8fe795a3e816bccae4bbf2b 270 Gene3D G3DSA:3.40.190.10 111 219 8.8E-96 T 14-10-2018 C2I25_14175 9602d5b2a8fe795a3e816bccae4bbf2b 270 Gene3D G3DSA:3.40.190.10 32 266 8.8E-96 T 14-10-2018 C2I25_14175 9602d5b2a8fe795a3e816bccae4bbf2b 270 SUPERFAMILY SSF53850 29 269 7.7E-79 T 14-10-2018 C2I25_14175 9602d5b2a8fe795a3e816bccae4bbf2b 270 Pfam PF03180 NLPA lipoprotein 30 268 1.2E-86 T 14-10-2018 IPR004872 Lipoprotein NlpA family C2I25_14175 9602d5b2a8fe795a3e816bccae4bbf2b 270 PIRSF PIRSF002854 1 270 1.4E-101 T 14-10-2018 IPR004872 Lipoprotein NlpA family C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 Pfam PF13432 Tetratricopeptide repeat 10 66 8.2E-5 T 14-10-2018 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 SUPERFAMILY SSF48452 130 217 2.28E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 SMART SM00028 68 101 4.2E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 SMART SM00028 165 198 440.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 SMART SM00028 33 67 19.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 Pfam PF13181 Tetratricopeptide repeat 102 127 0.18 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 Gene3D G3DSA:1.25.40.10 103 269 2.0E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 Pfam PF07719 Tetratricopeptide repeat 71 101 8.6E-6 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 Gene3D G3DSA:1.25.40.10 2 102 3.4E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_23025 6f8d1fe49b682c93d9d06156acbc0a9c 304 SUPERFAMILY SSF48452 4 158 4.93E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_01270 44ce520f3620857f921d65c060e76d01 258 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 252 4.4E-51 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_01270 44ce520f3620857f921d65c060e76d01 258 ProSitePatterns PS01229 Hypothetical cof family signature 2. 206 228 - T 14-10-2018 C2I25_01270 44ce520f3620857f921d65c060e76d01 258 SUPERFAMILY SSF56784 1 255 2.13E-59 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_01270 44ce520f3620857f921d65c060e76d01 258 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 14-10-2018 C2I25_01270 44ce520f3620857f921d65c060e76d01 258 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 225 9.6E-26 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_01270 44ce520f3620857f921d65c060e76d01 258 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 252 8.4E-59 T 14-10-2018 C2I25_01270 44ce520f3620857f921d65c060e76d01 258 Gene3D G3DSA:3.30.1240.10 80 181 4.1E-62 T 14-10-2018 C2I25_01270 44ce520f3620857f921d65c060e76d01 258 Gene3D G3DSA:3.40.50.1000 5 252 4.1E-62 T 14-10-2018 IPR023214 HAD superfamily C2I25_10150 0465b824fedf0bd8ba81357c700c849c 157 Gene3D G3DSA:3.40.50.300 2 148 1.4E-41 T 14-10-2018 C2I25_10150 0465b824fedf0bd8ba81357c700c849c 157 SUPERFAMILY SSF52540 25 120 1.06E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10150 0465b824fedf0bd8ba81357c700c849c 157 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 132 4.8E-38 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 C2I25_10150 0465b824fedf0bd8ba81357c700c849c 157 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 135 1.0E-40 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 Gene3D G3DSA:3.40.50.300 64 283 7.3E-44 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 Pfam PF13541 Subunit ChlI of Mg-chelatase 363 430 9.1E-9 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 Pfam PF13481 AAA domain 61 222 2.2E-17 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 SUPERFAMILY SSF52540 69 293 4.02E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 452 2.5E-211 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 45.319 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 Gene3D G3DSA:3.30.230.10 284 457 7.9E-21 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 SMART SM00382 90 244 1.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 SUPERFAMILY SSF54211 255 456 1.33E-43 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 PRINTS PR01874 DNA repair protein radA signature 322 345 6.2E-94 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 PRINTS PR01874 DNA repair protein radA signature 82 110 6.2E-94 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 PRINTS PR01874 DNA repair protein radA signature 213 241 6.2E-94 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 PRINTS PR01874 DNA repair protein radA signature 248 274 6.2E-94 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 PRINTS PR01874 DNA repair protein radA signature 10 34 6.2E-94 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 PRINTS PR01874 DNA repair protein radA signature 124 141 6.2E-94 T 14-10-2018 C2I25_11115 ebf086c88b0c17d6b909eb14ea779051 458 PRINTS PR01874 DNA repair protein radA signature 174 198 6.2E-94 T 14-10-2018 C2I25_02850 1ba6b4fc7bfaaed1fe85966f05b3afc1 607 Pfam PF00733 Asparagine synthase 243 599 1.1E-91 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 C2I25_02850 1ba6b4fc7bfaaed1fe85966f05b3afc1 607 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.6E-46 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I25_02850 1ba6b4fc7bfaaed1fe85966f05b3afc1 607 PIRSF PIRSF001589 1 606 2.8E-138 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I25_02850 1ba6b4fc7bfaaed1fe85966f05b3afc1 607 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 533 9.2E-157 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I25_02850 1ba6b4fc7bfaaed1fe85966f05b3afc1 607 Gene3D G3DSA:3.60.20.10 2 184 8.3E-66 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_02850 1ba6b4fc7bfaaed1fe85966f05b3afc1 607 SUPERFAMILY SSF56235 1 226 2.92E-66 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_02850 1ba6b4fc7bfaaed1fe85966f05b3afc1 607 SUPERFAMILY SSF52402 230 583 2.88E-68 T 14-10-2018 C2I25_07450 3692b989b0ef5927e6583b5e19241374 376 SMART SM00849 130 294 3.6E-25 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_07450 3692b989b0ef5927e6583b5e19241374 376 Gene3D G3DSA:3.40.250.10 8 116 6.4E-18 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_07450 3692b989b0ef5927e6583b5e19241374 376 SUPERFAMILY SSF56281 122 357 1.29E-41 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_07450 3692b989b0ef5927e6583b5e19241374 376 Pfam PF00581 Rhodanese-like domain 14 105 6.2E-10 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_07450 3692b989b0ef5927e6583b5e19241374 376 Gene3D G3DSA:3.60.15.10 119 355 3.1E-50 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_07450 3692b989b0ef5927e6583b5e19241374 376 SUPERFAMILY SSF52821 2 110 2.49E-18 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_07450 3692b989b0ef5927e6583b5e19241374 376 Pfam PF00753 Metallo-beta-lactamase superfamily 130 273 7.3E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_07450 3692b989b0ef5927e6583b5e19241374 376 SMART SM00450 6 109 2.5E-14 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Pfam PF07694 5TMR of 5TMR-LYT 37 136 1.2E-6 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Gene3D G3DSA:3.30.450.20 318 438 7.6E-26 T 14-10-2018 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 694 795 2.7E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 729 743 6.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 782 795 6.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 747 757 6.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 776 6.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SMART SM00086 530 570 3.2 T 14-10-2018 IPR001610 PAC motif C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SMART SM00086 393 435 2.7E-4 T 14-10-2018 IPR001610 PAC motif C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SMART SM00086 269 309 420.0 T 14-10-2018 IPR001610 PAC motif C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SMART SM00387 691 798 1.0E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SUPERFAMILY SSF47384 578 646 8.24E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SMART SM00388 585 649 9.7E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 319 441 2.0E-27 T 14-10-2018 IPR000014 PAS domain C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 450 576 3.0E-17 T 14-10-2018 IPR000014 PAS domain C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Gene3D G3DSA:3.30.565.10 649 799 4.2E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Gene3D G3DSA:3.30.450.20 224 317 1.8E-11 T 14-10-2018 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Pfam PF13426 PAS domain 472 569 7.5E-9 T 14-10-2018 IPR000014 PAS domain C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SUPERFAMILY SSF55785 217 316 4.61E-7 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SUPERFAMILY SSF55785 306 433 9.77E-23 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Gene3D G3DSA:1.10.287.130 571 648 6.5E-18 T 14-10-2018 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Pfam PF08448 PAS fold 230 310 3.6E-6 T 14-10-2018 IPR013656 PAS fold-4 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Pfam PF08448 PAS fold 332 437 6.2E-16 T 14-10-2018 IPR013656 PAS fold-4 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SUPERFAMILY SSF55874 646 796 1.44E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SUPERFAMILY SSF55785 441 568 7.57E-20 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Gene3D G3DSA:3.30.450.20 439 568 7.3E-23 T 14-10-2018 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 Pfam PF00512 His Kinase A (phospho-acceptor) domain 587 645 2.5E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SMART SM00091 454 527 0.0029 T 14-10-2018 IPR000014 PAS domain C2I25_27275 cfafa606c7a1c991f58f65a9589fc28f 801 SMART SM00091 321 386 5.1E-5 T 14-10-2018 IPR000014 PAS domain C2I25_03165 830c64b5fcfa40f97845545f62a3bbbb 458 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 22 115 4.9E-12 T 14-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 C2I25_03165 830c64b5fcfa40f97845545f62a3bbbb 458 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 234 436 4.8E-23 T 14-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 C2I25_01340 e1b78927e9b8796e148cc062e82e3e45 175 Pfam PF07609 Protein of unknown function (DUF1572) 3 164 5.8E-76 T 14-10-2018 IPR011466 Protein of unknown function DUF1572 C2I25_01340 e1b78927e9b8796e148cc062e82e3e45 175 SUPERFAMILY SSF109854 7 151 1.52E-20 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_01340 e1b78927e9b8796e148cc062e82e3e45 175 Gene3D G3DSA:1.20.120.450 9 150 4.2E-16 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 140 7.4E-34 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 Gene3D G3DSA:3.40.50.720 2 331 7.9E-128 T 14-10-2018 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 316 4.3E-28 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 SUPERFAMILY SSF55347 149 313 7.2E-54 T 14-10-2018 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 339 44.15 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 Gene3D G3DSA:3.30.360.10 147 313 7.9E-128 T 14-10-2018 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 344 3.2E-138 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 SMART SM00859 2 141 1.3E-48 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I25_18760 870baa94b82d6d7a6d149711ea803da4 345 SUPERFAMILY SSF51735 2 177 9.17E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_04785 a2ed3e90c81dcc3d069afc80ca02cb81 365 SUPERFAMILY SSF53383 4 360 7.11E-85 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_04785 a2ed3e90c81dcc3d069afc80ca02cb81 365 PIRSF PIRSF000524 1 363 4.2E-52 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 C2I25_04785 a2ed3e90c81dcc3d069afc80ca02cb81 365 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 7 359 6.0E-153 T 14-10-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 C2I25_04785 a2ed3e90c81dcc3d069afc80ca02cb81 365 Gene3D G3DSA:3.90.1150.10 9 353 4.2E-113 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_04785 a2ed3e90c81dcc3d069afc80ca02cb81 365 Pfam PF00266 Aminotransferase class-V 34 310 1.8E-27 T 14-10-2018 IPR000192 Aminotransferase class V domain C2I25_04785 a2ed3e90c81dcc3d069afc80ca02cb81 365 Gene3D G3DSA:3.40.640.10 17 263 4.2E-113 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_04785 a2ed3e90c81dcc3d069afc80ca02cb81 365 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 365 201.263 T 14-10-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 C2I25_04785 a2ed3e90c81dcc3d069afc80ca02cb81 365 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 3 362 4.1E-199 T 14-10-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 C2I25_10810 e01de89c1aad7fd4e8235a4928512984 247 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 35.894 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_10810 e01de89c1aad7fd4e8235a4928512984 247 PIRSF PIRSF001430 1 247 4.2E-84 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_10810 e01de89c1aad7fd4e8235a4928512984 247 Gene3D G3DSA:3.30.70.660 107 244 1.1E-49 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 C2I25_10810 e01de89c1aad7fd4e8235a4928512984 247 Gene3D G3DSA:3.30.70.580 1 105 1.5E-34 T 14-10-2018 C2I25_10810 e01de89c1aad7fd4e8235a4928512984 247 SUPERFAMILY SSF55120 2 247 9.35E-85 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_10810 e01de89c1aad7fd4e8235a4928512984 247 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 240 1.0E-68 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_10810 e01de89c1aad7fd4e8235a4928512984 247 Pfam PF01416 tRNA pseudouridine synthase 144 246 2.0E-34 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_10810 e01de89c1aad7fd4e8235a4928512984 247 Pfam PF01416 tRNA pseudouridine synthase 8 104 6.3E-9 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_04435 c227207c4e9bfee54ba0f9cbb6deeebc 79 Pfam PF13050 Protein of unknown function (DUF3911) 1 77 2.0E-54 T 14-10-2018 IPR025022 Protein of unknown function DUF3911 C2I25_11780 9c39ac8ecead29d91cc71f14e8b27a47 235 SUPERFAMILY SSF46894 130 230 4.76E-32 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_11780 9c39ac8ecead29d91cc71f14e8b27a47 235 SMART SM00448 4 114 1.7E-48 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_11780 9c39ac8ecead29d91cc71f14e8b27a47 235 Gene3D G3DSA:1.10.10.10 132 235 4.3E-40 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_11780 9c39ac8ecead29d91cc71f14e8b27a47 235 Pfam PF00072 Response regulator receiver domain 6 115 9.4E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_11780 9c39ac8ecead29d91cc71f14e8b27a47 235 SUPERFAMILY SSF52172 1 123 5.69E-45 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_11780 9c39ac8ecead29d91cc71f14e8b27a47 235 SMART SM00862 153 229 1.6E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_11780 9c39ac8ecead29d91cc71f14e8b27a47 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 9.2E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_11780 9c39ac8ecead29d91cc71f14e8b27a47 235 Gene3D G3DSA:3.40.50.2300 2 131 5.6E-42 T 14-10-2018 C2I25_21340 b0e030d9ddb877bc00642646138d809a 46 TIGRFAM TIGR03731 lantibio_gallid: lantibiotic, gallidermin/nisin family 6 46 2.4E-18 T 14-10-2018 IPR006079 Lantibiotic, Type A, Bacillales-type GO:0005576|GO:0042742 C2I25_21340 b0e030d9ddb877bc00642646138d809a 46 Pfam PF02052 Gallidermin 4 46 1.7E-16 T 14-10-2018 IPR006079 Lantibiotic, Type A, Bacillales-type GO:0005576|GO:0042742 C2I25_21345 b0e030d9ddb877bc00642646138d809a 46 TIGRFAM TIGR03731 lantibio_gallid: lantibiotic, gallidermin/nisin family 6 46 2.4E-18 T 14-10-2018 IPR006079 Lantibiotic, Type A, Bacillales-type GO:0005576|GO:0042742 C2I25_21345 b0e030d9ddb877bc00642646138d809a 46 Pfam PF02052 Gallidermin 4 46 1.7E-16 T 14-10-2018 IPR006079 Lantibiotic, Type A, Bacillales-type GO:0005576|GO:0042742 C2I25_21350 b0e030d9ddb877bc00642646138d809a 46 TIGRFAM TIGR03731 lantibio_gallid: lantibiotic, gallidermin/nisin family 6 46 2.4E-18 T 14-10-2018 IPR006079 Lantibiotic, Type A, Bacillales-type GO:0005576|GO:0042742 C2I25_21350 b0e030d9ddb877bc00642646138d809a 46 Pfam PF02052 Gallidermin 4 46 1.7E-16 T 14-10-2018 IPR006079 Lantibiotic, Type A, Bacillales-type GO:0005576|GO:0042742 C2I25_26905 af1ba9f8446da91a3b693372d1704221 456 Gene3D G3DSA:1.10.10.10 1 68 2.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_26905 af1ba9f8446da91a3b693372d1704221 456 Gene3D G3DSA:3.40.640.10 69 438 5.3E-80 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_26905 af1ba9f8446da91a3b693372d1704221 456 SUPERFAMILY SSF46785 3 75 8.97E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_26905 af1ba9f8446da91a3b693372d1704221 456 SUPERFAMILY SSF53383 63 441 3.11E-65 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_26905 af1ba9f8446da91a3b693372d1704221 456 SMART SM00345 7 66 3.1E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26905 af1ba9f8446da91a3b693372d1704221 456 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.1E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26905 af1ba9f8446da91a3b693372d1704221 456 Pfam PF00155 Aminotransferase class I and II 81 437 6.6E-22 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 Gene3D G3DSA:3.30.1480.10 1 124 3.6E-48 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 Gene3D G3DSA:3.30.300.20 198 276 4.1E-33 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 Pfam PF13184 NusA-like KH domain 229 296 2.6E-26 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 SUPERFAMILY SSF50249 132 198 1.23E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 SMART SM00316 133 199 9.3E-10 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 SMART SM00322 229 292 0.22 T 14-10-2018 IPR004087 K Homology domain GO:0003676 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 SMART SM00322 300 368 0.2 T 14-10-2018 IPR004087 K Homology domain GO:0003676 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 8.3E-128 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 Gene3D G3DSA:2.40.50.140 136 197 9.7E-24 T 14-10-2018 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 SUPERFAMILY SSF54814 278 342 6.28E-17 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 SUPERFAMILY SSF54814 199 277 9.81E-30 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 Pfam PF00575 S1 RNA binding domain 133 195 1.4E-10 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 Gene3D G3DSA:3.30.300.20 277 367 1.2E-32 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 367 30.503 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 SUPERFAMILY SSF69705 1 126 4.58E-43 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 C2I25_20435 9d64e646b252163881f41e877b5ec03f 368 Pfam PF08529 NusA N-terminal domain 4 123 2.6E-43 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 C2I25_00670 9bc599b21470bd4c4f6fffeea4931dc6 978 Pfam PF10145 Phage-related minor tail protein 117 311 1.5E-24 T 14-10-2018 IPR010090 Phage tail tape measure protein C2I25_00670 9bc599b21470bd4c4f6fffeea4931dc6 978 SUPERFAMILY SSF48371 551 795 7.0E-7 T 14-10-2018 IPR016024 Armadillo-type fold C2I25_00670 9bc599b21470bd4c4f6fffeea4931dc6 978 Gene3D G3DSA:1.10.287.700 643 745 4.8E-7 T 14-10-2018 C2I25_01015 05ebf0cd5f3f93667836b7c8fc1125aa 156 Gene3D G3DSA:3.90.1170.40 3 148 6.2E-53 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_01015 05ebf0cd5f3f93667836b7c8fc1125aa 156 SUPERFAMILY SSF54690 4 139 1.06E-46 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_01015 05ebf0cd5f3f93667836b7c8fc1125aa 156 Pfam PF02391 MoaE protein 10 119 1.7E-35 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_19545 b176d1d51075d5f5557ef6b2ccc33fcd 78 Gene3D G3DSA:3.40.30.10 1 78 2.6E-26 T 14-10-2018 C2I25_19545 b176d1d51075d5f5557ef6b2ccc33fcd 78 Pfam PF00462 Glutaredoxin 4 63 5.3E-15 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 C2I25_19545 b176d1d51075d5f5557ef6b2ccc33fcd 78 SUPERFAMILY SSF52833 2 76 8.01E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_19545 b176d1d51075d5f5557ef6b2ccc33fcd 78 TIGRFAM TIGR02196 GlrX_YruB: glutaredoxin-like protein, YruB-family 3 76 5.6E-31 T 14-10-2018 IPR011911 Glutaredoxin-like protein, YruB C2I25_08040 6f484bbcd35e2ba06953c96bf5b5dc4c 433 Pfam PF05525 Branched-chain amino acid transport protein 6 426 1.4E-141 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_08040 6f484bbcd35e2ba06953c96bf5b5dc4c 433 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 414 5.1E-125 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 SMART SM01004 4 323 1.7E-240 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 322 1.5E-150 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 1.2E-59 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 1.2E-59 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 1.2E-59 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 1.2E-59 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 1.2E-59 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 1.2E-59 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 Gene3D G3DSA:3.20.20.70 2 324 4.0E-149 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 SUPERFAMILY SSF51569 5 325 2.49E-144 T 14-10-2018 C2I25_16970 68a162bc186f71c99d70f083af26f4ba 329 PIRSF PIRSF001415 1 326 7.8E-155 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SUPERFAMILY SSF56059 666 927 3.54E-102 T 14-10-2018 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SUPERFAMILY SSF52440 1 127 2.01E-49 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.8E-62 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 3.8E-62 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.8E-62 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-62 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.8E-62 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 3.8E-62 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-62 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SUPERFAMILY SSF48108 395 546 1.29E-49 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Gene3D G3DSA:3.40.50.1380 930 1066 1.1E-36 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Gene3D G3DSA:3.40.50.20 547 655 1.7E-46 T 14-10-2018 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Pfam PF02142 MGS-like domain 950 1036 8.4E-19 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Gene3D G3DSA:1.10.1030.10 404 546 1.4E-43 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 4.8E-40 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 7.3E-81 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SMART SM01096 420 540 2.1E-65 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1064 13.497 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Gene3D G3DSA:3.30.470.20 120 401 7.1E-124 T 14-10-2018 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Gene3D G3DSA:3.40.50.20 1 116 1.7E-48 T 14-10-2018 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SUPERFAMILY SSF52335 936 1068 5.76E-32 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SMART SM00851 949 1036 1.1E-25 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SUPERFAMILY SSF56059 128 399 1.18E-108 T 14-10-2018 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SMART SM01209 674 837 0.0024 T 14-10-2018 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 SUPERFAMILY SSF52440 549 668 1.11E-48 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 2.5E-41 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Gene3D G3DSA:3.30.470.20 659 929 1.3E-108 T 14-10-2018 C2I25_20065 f5ecd7672e51ad6be3c3bf6bda434c06 1072 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.142 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_17665 5c489e4d264c01bd08c7a9b61280b174 85 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.83 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17665 5c489e4d264c01bd08c7a9b61280b174 85 Gene3D G3DSA:1.20.58.110 1 85 2.3E-28 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17665 5c489e4d264c01bd08c7a9b61280b174 85 SUPERFAMILY SSF46992 3 85 3.01E-28 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17665 5c489e4d264c01bd08c7a9b61280b174 85 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 2.1E-28 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17665 5c489e4d264c01bd08c7a9b61280b174 85 Pfam PF01649 Ribosomal protein S20 2 84 8.0E-26 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17665 5c489e4d264c01bd08c7a9b61280b174 85 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 84 6.0E-33 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 SMART SM00354 1 71 2.7E-28 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 Gene3D G3DSA:1.10.260.40 1 59 7.4E-21 T 14-10-2018 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 Gene3D G3DSA:3.40.50.2300 158 285 9.4E-62 T 14-10-2018 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 SUPERFAMILY SSF53822 61 325 1.88E-59 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 Gene3D G3DSA:3.40.50.2300 61 302 9.4E-62 T 14-10-2018 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.3E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.3E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 4.0E-19 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 Pfam PF13377 Periplasmic binding protein-like domain 167 325 1.8E-28 T 14-10-2018 C2I25_18255 9b9426a2b45356e7446a17d8f047cd12 325 SUPERFAMILY SSF47413 1 59 4.78E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_10675 492c74d486427a2c860f23f081af342b 448 SUPERFAMILY SSF53738 3 180 4.32E-46 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Gene3D G3DSA:3.40.120.10 256 339 8.1E-75 T 14-10-2018 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 5.1E-16 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 SUPERFAMILY SSF55957 357 446 1.31E-26 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 SUPERFAMILY SSF53738 257 365 1.88E-33 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Gene3D G3DSA:3.40.120.10 3 155 6.8E-62 T 14-10-2018 C2I25_10675 492c74d486427a2c860f23f081af342b 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 2.3E-12 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 2.3E-12 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 2.3E-12 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.593 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Gene3D G3DSA:3.30.310.50 370 448 8.8E-31 T 14-10-2018 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 6.2E-16 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 1.8E-188 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 1.8E-43 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 368 1.5E-35 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_10675 492c74d486427a2c860f23f081af342b 448 Gene3D G3DSA:3.40.120.10 173 362 8.1E-75 T 14-10-2018 C2I25_10675 492c74d486427a2c860f23f081af342b 448 SUPERFAMILY SSF53738 158 256 3.26E-26 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_15960 0cfc8998bd3134f2edaebacfa95740f9 210 Pfam PF00583 Acetyltransferase (GNAT) family 49 118 1.1E-4 T 14-10-2018 IPR000182 GNAT domain C2I25_15960 0cfc8998bd3134f2edaebacfa95740f9 210 PIRSF PIRSF021278 2 210 8.0E-86 T 14-10-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 C2I25_15960 0cfc8998bd3134f2edaebacfa95740f9 210 Gene3D G3DSA:3.40.630.30 2 210 2.9E-86 T 14-10-2018 C2I25_15960 0cfc8998bd3134f2edaebacfa95740f9 210 SUPERFAMILY SSF55729 43 119 1.45E-7 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25990 0c93a225416bb0553da38c5777bbde87 174 Pfam PF08877 MepB protein 36 157 5.9E-49 T 14-10-2018 IPR011235 MepB-like C2I25_25990 0c93a225416bb0553da38c5777bbde87 174 Gene3D G3DSA:3.40.1350.140 13 169 5.4E-57 T 14-10-2018 IPR038231 MepB-like superfamily C2I25_25990 0c93a225416bb0553da38c5777bbde87 174 PIRSF PIRSF032285 9 174 2.2E-67 T 14-10-2018 IPR011235 MepB-like C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 Gene3D G3DSA:2.40.50.140 560 669 6.9E-36 T 14-10-2018 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 SUPERFAMILY SSF47323 372 582 2.29E-47 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 Pfam PF09334 tRNA synthetases class I (M) 17 382 3.1E-121 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 17 532 9.6E-180 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 Gene3D G3DSA:1.10.730.10 360 530 3.4E-50 T 14-10-2018 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 26 35 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 19 32 9.2E-34 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 51 65 9.2E-34 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 99 110 9.2E-34 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 245 256 9.2E-34 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 370 381 9.2E-34 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 278 293 9.2E-34 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 Hamap MF_01228 Methionine--tRNA ligase [metG]. 10 531 51.153 T 14-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 539 669 6.5E-48 T 14-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 SUPERFAMILY SSF50249 563 668 7.83E-33 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 SUPERFAMILY SSF52374 14 373 1.34E-118 T 14-10-2018 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 Gene3D G3DSA:3.40.50.620 17 353 2.3E-153 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 Pfam PF08264 Anticodon-binding domain of tRNA 405 509 2.8E-8 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 Pfam PF01588 Putative tRNA binding domain 575 667 2.9E-27 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 C2I25_11420 d81164b6bd823e51e22cca59f56b6a2f 669 Gene3D G3DSA:2.170.220.10 128 247 2.3E-153 T 14-10-2018 C2I25_20660 7f7e88dab374ecd4661c9e785fda6fb7 143 Gene3D G3DSA:1.20.1500.10 1 124 1.2E-37 T 14-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I25_20660 7f7e88dab374ecd4661c9e785fda6fb7 143 PIRSF PIRSF021287 1 123 3.1E-53 T 14-10-2018 IPR016783 Biofilm formation YmcA C2I25_20660 7f7e88dab374ecd4661c9e785fda6fb7 143 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 2.4E-25 T 14-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA C2I25_20660 7f7e88dab374ecd4661c9e785fda6fb7 143 SUPERFAMILY SSF158622 4 123 8.89E-37 T 14-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I25_26040 d2a1f7c0af2b0d7a9f808222c8733617 187 SUPERFAMILY SSF55729 5 175 6.99E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26040 d2a1f7c0af2b0d7a9f808222c8733617 187 Gene3D G3DSA:3.40.630.30 1 155 3.6E-15 T 14-10-2018 C2I25_26040 d2a1f7c0af2b0d7a9f808222c8733617 187 Pfam PF00583 Acetyltransferase (GNAT) family 42 152 4.9E-10 T 14-10-2018 IPR000182 GNAT domain C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 Gene3D G3DSA:1.20.200.10 137 404 1.6E-109 T 14-10-2018 C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 Gene3D G3DSA:1.10.40.30 406 461 1.8E-30 T 14-10-2018 C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 92.397 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 SUPERFAMILY SSF48557 3 458 1.46E-154 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 Pfam PF00206 Lyase 11 340 1.3E-115 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 4.8E-34 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 4.8E-34 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 4.8E-34 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 4.8E-34 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 Gene3D G3DSA:1.10.275.10 1 136 1.1E-57 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 459 7.8E-236 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_02765 f2c9d3578e993396a77f7e5687121433 462 Pfam PF10415 Fumarase C C-terminus 406 458 1.6E-28 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_01845 35413310d2201764abd25459da96eb3a 428 SMART SM00287 57 118 7.6E-11 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_01845 35413310d2201764abd25459da96eb3a 428 SMART SM00287 213 274 1.3E-8 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_01845 35413310d2201764abd25459da96eb3a 428 SMART SM00287 129 191 2.0E-12 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_01845 35413310d2201764abd25459da96eb3a 428 Gene3D G3DSA:2.30.30.40 56 119 2.5E-18 T 14-10-2018 C2I25_01845 35413310d2201764abd25459da96eb3a 428 Pfam PF00877 NlpC/P60 family 321 424 5.5E-24 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I25_01845 35413310d2201764abd25459da96eb3a 428 SUPERFAMILY SSF54001 302 426 2.35E-31 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_01845 35413310d2201764abd25459da96eb3a 428 Pfam PF08239 Bacterial SH3 domain 222 272 7.0E-14 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_01845 35413310d2201764abd25459da96eb3a 428 Pfam PF08239 Bacterial SH3 domain 137 187 4.1E-16 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_01845 35413310d2201764abd25459da96eb3a 428 Pfam PF08239 Bacterial SH3 domain 66 115 1.3E-14 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_01845 35413310d2201764abd25459da96eb3a 428 Gene3D G3DSA:3.90.1720.10 271 423 2.6E-31 T 14-10-2018 C2I25_01845 35413310d2201764abd25459da96eb3a 428 SUPERFAMILY SSF50044 244 298 1.74E-5 T 14-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 C2I25_01845 35413310d2201764abd25459da96eb3a 428 Gene3D G3DSA:2.30.30.40 129 187 1.3E-20 T 14-10-2018 C2I25_01845 35413310d2201764abd25459da96eb3a 428 Gene3D G3DSA:2.30.30.40 212 270 4.3E-15 T 14-10-2018 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 SMART SM00279 187 222 5.0E-17 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 18 183 2.3E-54 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Gene3D G3DSA:3.40.50.1010 19 292 3.3E-101 T 14-10-2018 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 SUPERFAMILY SSF47807 185 300 3.29E-34 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Gene3D G3DSA:1.20.1060.10 506 620 2.1E-44 T 14-10-2018 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 ProSitePatterns PS00447 DNA polymerase family A signature. 717 736 - T 14-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Gene3D G3DSA:3.30.420.10 312 504 1.7E-66 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 SUPERFAMILY SSF56672 485 891 1.22E-159 T 14-10-2018 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Gene3D G3DSA:1.10.150.20 188 261 3.3E-101 T 14-10-2018 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 717 742 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 640 655 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 693 706 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 808 824 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 776 787 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 617 639 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 838 851 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 663 686 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 754 765 6.0E-82 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 SUPERFAMILY SSF53098 315 482 3.03E-45 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Gene3D G3DSA:1.10.150.20 672 815 3.7E-110 T 14-10-2018 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Pfam PF00476 DNA polymerase family A 513 889 2.5E-161 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 SUPERFAMILY SSF88723 16 183 2.01E-56 T 14-10-2018 IPR029060 PIN-like domain superfamily C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 186 279 2.7E-36 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 TIGRFAM TIGR00593 pola: DNA polymerase I 19 891 0.0 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 SMART SM00474 315 481 4.0E-12 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 SMART SM00482 648 855 1.7E-119 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 SMART SM00475 17 276 1.5E-151 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 C2I25_16370 55b80e8a072880be9d3fa8b058917d6d 891 Gene3D G3DSA:3.30.70.370 626 887 3.7E-110 T 14-10-2018 C2I25_25935 3b3ab5cacec5ffd1d6528a65066b155d 199 SMART SM00014 61 166 2.1E-20 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_25935 3b3ab5cacec5ffd1d6528a65066b155d 199 Pfam PF01569 PAP2 superfamily 66 172 1.2E-15 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_25935 3b3ab5cacec5ffd1d6528a65066b155d 199 Gene3D G3DSA:1.20.144.10 76 180 3.6E-20 T 14-10-2018 C2I25_25935 3b3ab5cacec5ffd1d6528a65066b155d 199 SUPERFAMILY SSF48317 3 167 1.57E-37 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I25_28320 a608e3c42dcdce95c7a4c006546bc370 111 Pfam PF08863 YolD-like protein 19 110 8.6E-21 T 14-10-2018 IPR014962 YolD-like protein C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 Gene3D G3DSA:1.10.287.130 268 347 6.8E-16 T 14-10-2018 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 442 2.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 2.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 2.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 2.9E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 Gene3D G3DSA:3.30.450.20 74 173 1.3E-34 T 14-10-2018 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 Pfam PF11346 Protein of unknown function (DUF3149) 8 38 2.2E-9 T 14-10-2018 IPR021494 Protein of unknown function DUF3149 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 SUPERFAMILY SSF47384 274 345 2.35E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 Pfam PF02743 Cache domain 83 213 1.2E-13 T 14-10-2018 IPR033479 Double Cache domain 1 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 SMART SM00388 284 349 1.7E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 Gene3D G3DSA:3.30.450.20 46 225 1.3E-34 T 14-10-2018 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 286 346 1.5E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 394 496 9.3E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 Gene3D G3DSA:3.30.565.10 349 497 4.6E-41 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 SMART SM00387 391 497 2.0E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04740 1daf7cfa271b318540cf2473708c4dce 498 SUPERFAMILY SSF55874 346 495 8.91E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_11680 a94fb26d12eb5e254ef49954b3171ff9 239 Gene3D G3DSA:3.40.50.150 1 239 6.4E-88 T 14-10-2018 C2I25_11680 a94fb26d12eb5e254ef49954b3171ff9 239 Pfam PF02527 rRNA small subunit methyltransferase G 21 203 9.7E-58 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 C2I25_11680 a94fb26d12eb5e254ef49954b3171ff9 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.374 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 C2I25_11680 a94fb26d12eb5e254ef49954b3171ff9 239 PIRSF PIRSF003078 1 220 9.3E-60 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 C2I25_11680 a94fb26d12eb5e254ef49954b3171ff9 239 SUPERFAMILY SSF53335 1 237 2.43E-49 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_11680 a94fb26d12eb5e254ef49954b3171ff9 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 216 7.3E-52 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 Gene3D G3DSA:1.25.40.10 5 132 2.4E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 SMART SM00028 21 54 34.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 SMART SM00028 184 217 0.0048 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 SMART SM00028 287 320 270.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 SMART SM00028 88 121 88.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 Gene3D G3DSA:1.25.40.10 136 426 3.5E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 SUPERFAMILY SSF48452 15 228 2.02E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 Pfam PF13432 Tetratricopeptide repeat 156 217 3.8E-7 T 14-10-2018 C2I25_13430 68901acdad59ddb992bc31aef8dcbd31 503 SUPERFAMILY SSF48452 215 320 1.18E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_09695 2ba9d2c4102c7e2fbca651ba40fab2cd 329 Pfam PF01207 Dihydrouridine synthase (Dus) 15 318 6.1E-50 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I25_09695 2ba9d2c4102c7e2fbca651ba40fab2cd 329 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I25_09695 2ba9d2c4102c7e2fbca651ba40fab2cd 329 Gene3D G3DSA:3.20.20.70 13 247 2.2E-61 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_09695 2ba9d2c4102c7e2fbca651ba40fab2cd 329 SUPERFAMILY SSF51395 13 319 3.87E-59 T 14-10-2018 C2I25_09695 2ba9d2c4102c7e2fbca651ba40fab2cd 329 PIRSF PIRSF006621 1 328 2.2E-83 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I25_19080 975e90f1556701191069006c36f6d271 396 SUPERFAMILY SSF56601 1 287 4.39E-85 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_19080 975e90f1556701191069006c36f6d271 396 SMART SM00936 287 378 5.4E-21 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_19080 975e90f1556701191069006c36f6d271 396 Gene3D G3DSA:2.60.410.10 287 377 1.5E-19 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_19080 975e90f1556701191069006c36f6d271 396 SUPERFAMILY SSF69189 279 376 5.1E-20 T 14-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_19080 975e90f1556701191069006c36f6d271 396 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 287 377 7.7E-20 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_19080 975e90f1556701191069006c36f6d271 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 123 140 1.3E-17 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_19080 975e90f1556701191069006c36f6d271 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 150 163 1.3E-17 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_19080 975e90f1556701191069006c36f6d271 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 1.3E-17 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_19080 975e90f1556701191069006c36f6d271 396 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 37 267 4.8E-90 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_19080 975e90f1556701191069006c36f6d271 396 Gene3D G3DSA:3.40.710.10 17 285 7.1E-99 T 14-10-2018 C2I25_00940 0acd1ed64edc9cc8e0acfe724e4b8a6a 279 Pfam PF00797 N-acetyltransferase 22 268 7.0E-46 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_00940 0acd1ed64edc9cc8e0acfe724e4b8a6a 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 102 127 2.6E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_00940 0acd1ed64edc9cc8e0acfe724e4b8a6a 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 2.6E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_00940 0acd1ed64edc9cc8e0acfe724e4b8a6a 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 2.6E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_00940 0acd1ed64edc9cc8e0acfe724e4b8a6a 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 261 274 2.6E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_00940 0acd1ed64edc9cc8e0acfe724e4b8a6a 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 2.6E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_00940 0acd1ed64edc9cc8e0acfe724e4b8a6a 279 SUPERFAMILY SSF54001 2 275 1.59E-64 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_00940 0acd1ed64edc9cc8e0acfe724e4b8a6a 279 Gene3D G3DSA:3.30.2140.20 1 279 1.9E-108 T 14-10-2018 C2I25_15845 d48db0ee7fe9315912ba162356820981 339 SUPERFAMILY SSF55729 6 174 2.4E-40 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_15845 d48db0ee7fe9315912ba162356820981 339 Pfam PF13302 Acetyltransferase (GNAT) domain 11 150 1.4E-22 T 14-10-2018 IPR000182 GNAT domain C2I25_15845 d48db0ee7fe9315912ba162356820981 339 Gene3D G3DSA:3.40.630.30 2 176 1.5E-45 T 14-10-2018 C2I25_15845 d48db0ee7fe9315912ba162356820981 339 Gene3D G3DSA:3.40.630.30 177 339 1.1E-43 T 14-10-2018 C2I25_15845 d48db0ee7fe9315912ba162356820981 339 Pfam PF00583 Acetyltransferase (GNAT) family 199 313 7.4E-15 T 14-10-2018 IPR000182 GNAT domain C2I25_15845 d48db0ee7fe9315912ba162356820981 339 SUPERFAMILY SSF55729 180 320 4.12E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_08480 1368693983eb87b68acb1ff6b4c6cdf0 182 Pfam PF09335 SNARE associated Golgi protein 33 149 4.5E-18 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_23705 577d3288ae498b789b9908df206b72a3 457 Gene3D G3DSA:3.30.565.10 303 457 3.3E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23705 577d3288ae498b789b9908df206b72a3 457 Gene3D G3DSA:1.10.287.130 178 297 2.1E-27 T 14-10-2018 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 SUPERFAMILY SSF158472 176 227 8.11E-5 T 14-10-2018 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 296 4.8E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 454 1.0E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_23705 577d3288ae498b789b9908df206b72a3 457 Pfam PF00672 HAMP domain 177 225 5.8E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 SUPERFAMILY SSF55874 286 453 1.44E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23705 577d3288ae498b789b9908df206b72a3 457 SMART SM00388 230 296 4.6E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 SMART SM00304 174 229 1.3E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 SMART SM00387 342 455 1.8E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_23705 577d3288ae498b789b9908df206b72a3 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 5.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 5.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 5.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 5.2E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23705 577d3288ae498b789b9908df206b72a3 457 SUPERFAMILY SSF47384 213 297 2.35E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 SUPERFAMILY SSF52540 296 529 3.37E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 SUPERFAMILY SSF52540 2 255 1.33E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 Gene3D G3DSA:3.40.50.300 287 541 4.4E-44 T 14-10-2018 C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 Gene3D G3DSA:3.40.50.300 1 280 2.7E-59 T 14-10-2018 C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 SMART SM00382 26 228 1.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 SMART SM00382 344 513 3.1 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 Pfam PF00005 ABC transporter 18 184 1.3E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 Pfam PF12848 ABC transporter 224 300 1.8E-19 T 14-10-2018 IPR032781 ABC-transporter extension domain C2I25_24840 a11a43ed0b5acde13f1122b22ab7ed20 541 Pfam PF00005 ABC transporter 335 468 4.2E-15 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 212 1.4E-84 T 14-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 Pfam PF01470 Pyroglutamyl peptidase 3 201 1.5E-84 T 14-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 4.9E-48 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 4.9E-48 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 4.9E-48 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 4.9E-48 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 4.9E-48 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 201 41.307 T 14-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 Gene3D G3DSA:3.40.630.20 1 215 7.2E-89 T 14-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 PIRSF PIRSF015592 1 213 1.7E-89 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 14-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 14-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 C2I25_24245 44bf2e69c3895384a86e2acd8855d71a 215 SUPERFAMILY SSF53182 1 213 4.32E-73 T 14-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 C2I25_10485 d2829d5b923f462861941be2543692a3 288 SUPERFAMILY SSF53850 88 282 1.18E-31 T 14-10-2018 C2I25_10485 d2829d5b923f462861941be2543692a3 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_10485 d2829d5b923f462861941be2543692a3 288 Gene3D G3DSA:1.10.10.10 1 87 1.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_10485 d2829d5b923f462861941be2543692a3 288 Gene3D G3DSA:3.40.190.290 90 286 2.1E-34 T 14-10-2018 C2I25_10485 d2829d5b923f462861941be2543692a3 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_10485 d2829d5b923f462861941be2543692a3 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_10485 d2829d5b923f462861941be2543692a3 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_10485 d2829d5b923f462861941be2543692a3 288 Pfam PF03466 LysR substrate binding domain 86 282 1.1E-37 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_10485 d2829d5b923f462861941be2543692a3 288 SUPERFAMILY SSF46785 1 101 3.81E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_25080 efea7900acdb5a706c475b1a46623508 400 Gene3D G3DSA:3.90.1150.10 26 383 4.5E-115 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_25080 efea7900acdb5a706c475b1a46623508 400 Pfam PF00155 Aminotransferase class I and II 34 383 1.7E-61 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_25080 efea7900acdb5a706c475b1a46623508 400 Gene3D G3DSA:3.40.640.10 45 285 4.5E-115 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_25080 efea7900acdb5a706c475b1a46623508 400 SUPERFAMILY SSF53383 6 385 2.2E-104 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_25080 efea7900acdb5a706c475b1a46623508 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 C2I25_26805 fc4354faadb7b79f73eb6b0b2b758586 227 Pfam PF17294 Uncharacterised lipoprotein family 35 205 8.3E-44 T 14-10-2018 IPR035253 Putative lipoprotein, bacteria C2I25_26805 fc4354faadb7b79f73eb6b0b2b758586 227 Gene3D G3DSA:2.40.40.60 68 170 2.3E-18 T 14-10-2018 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 Pfam PF00571 CBS domain 97 144 3.4E-6 T 14-10-2018 IPR000644 CBS domain C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 Pfam PF00571 CBS domain 153 204 6.1E-8 T 14-10-2018 IPR000644 CBS domain C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 87.281 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 1.8E-167 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 SUPERFAMILY SSF54631 66 208 8.21E-32 T 14-10-2018 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 PIRSF PIRSF000130 1 487 9.4E-211 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 Gene3D G3DSA:3.20.20.70 1 487 8.8E-227 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 SMART SM00116 98 148 2.1E-6 T 14-10-2018 IPR000644 CBS domain C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 SMART SM00116 161 209 7.3E-9 T 14-10-2018 IPR000644 CBS domain C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 SMART SM01240 9 474 0.0 T 14-10-2018 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 7.0E-201 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 C2I25_11585 1a6876b4e3b327f1777d5305273963b2 487 SUPERFAMILY SSF51412 5 478 6.02E-126 T 14-10-2018 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 PRINTS PR00175 Sodium/alanine symporter signature 211 230 1.8E-54 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 PRINTS PR00175 Sodium/alanine symporter signature 92 114 1.8E-54 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 PRINTS PR00175 Sodium/alanine symporter signature 306 324 1.8E-54 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 PRINTS PR00175 Sodium/alanine symporter signature 409 429 1.8E-54 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 PRINTS PR00175 Sodium/alanine symporter signature 183 201 1.8E-54 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 PRINTS PR00175 Sodium/alanine symporter signature 350 372 1.8E-54 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 Pfam PF01235 Sodium:alanine symporter family 55 449 3.2E-149 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_28105 0553f6e51ae31259e85ab1b6122c1600 455 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 5.4E-159 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SUPERFAMILY SSF50249 314 396 5.82E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Gene3D G3DSA:1.10.150.20 501 580 4.7E-28 T 14-10-2018 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Gene3D G3DSA:3.30.470.90 74 314 5.1E-102 T 14-10-2018 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Pfam PF12826 Helix-hairpin-helix motif 506 568 1.5E-24 T 14-10-2018 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 319 395 7.4E-34 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SUPERFAMILY SSF52113 594 667 1.13E-19 T 14-10-2018 IPR036420 BRCT domain superfamily C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Gene3D G3DSA:3.40.50.10190 581 668 5.1E-25 T 14-10-2018 IPR036420 BRCT domain superfamily C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Gene3D G3DSA:2.40.50.140 315 387 1.1E-29 T 14-10-2018 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SMART SM00532 5 444 3.1E-276 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Gene3D G3DSA:1.10.150.20 428 500 2.2E-31 T 14-10-2018 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 665 2.5E-14 T 14-10-2018 IPR001357 BRCT domain C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Gene3D G3DSA:1.10.287.610 1 73 1.6E-25 T 14-10-2018 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 116 145 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Hamap MF_01588 DNA ligase [ligA]. 4 667 53.174 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Pfam PF14520 Helix-hairpin-helix domain 444 496 1.5E-6 T 14-10-2018 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 6 315 1.2E-128 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 328 343 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SMART SM00292 593 669 1.6E-14 T 14-10-2018 IPR001357 BRCT domain C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SUPERFAMILY SSF47781 401 581 4.82E-66 T 14-10-2018 IPR010994 RuvA domain 2-like C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 PIRSF PIRSF001604 1 669 1.3E-260 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 404 430 5.0E-10 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SMART SM00278 476 495 0.98 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SMART SM00278 442 461 120.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SMART SM00278 540 559 3.8 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 663 1.6E-269 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 SUPERFAMILY SSF56091 4 313 1.31E-121 T 14-10-2018 C2I25_09845 40308d9a05f3627d7fa82273d5de8603 669 Gene3D G3DSA:2.20.70.80 388 425 2.8E-11 T 14-10-2018 C2I25_10365 5f160976a6b56d163afb366dc6fbdcc0 326 SMART SM00382 34 233 2.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_10365 5f160976a6b56d163afb366dc6fbdcc0 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 3.3E-28 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_10365 5f160976a6b56d163afb366dc6fbdcc0 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 8.8E-16 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_10365 5f160976a6b56d163afb366dc6fbdcc0 326 SUPERFAMILY SSF52540 5 254 1.82E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10365 5f160976a6b56d163afb366dc6fbdcc0 326 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10365 5f160976a6b56d163afb366dc6fbdcc0 326 Pfam PF00005 ABC transporter 26 183 3.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10365 5f160976a6b56d163afb366dc6fbdcc0 326 Gene3D G3DSA:3.40.50.300 3 326 6.1E-101 T 14-10-2018 C2I25_11655 4c309b374e98980b0a309ddddf39478e 115 Pfam PF00825 Ribonuclease P 1 107 2.4E-36 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 C2I25_11655 4c309b374e98980b0a309ddddf39478e 115 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 108 1.9E-33 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 C2I25_11655 4c309b374e98980b0a309ddddf39478e 115 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 14-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 C2I25_11655 4c309b374e98980b0a309ddddf39478e 115 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 20.589 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 C2I25_11655 4c309b374e98980b0a309ddddf39478e 115 SUPERFAMILY SSF54211 1 109 1.67E-34 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_11655 4c309b374e98980b0a309ddddf39478e 115 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 114 3.0E-57 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 C2I25_11655 4c309b374e98980b0a309ddddf39478e 115 Gene3D G3DSA:3.30.230.10 1 114 4.0E-38 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_26705 5c32237db0158542bed0546030038e1f 92 Gene3D G3DSA:2.10.260.10 1 52 4.1E-21 T 14-10-2018 C2I25_26705 5c32237db0158542bed0546030038e1f 92 SUPERFAMILY SSF89447 1 52 2.09E-14 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I25_26705 5c32237db0158542bed0546030038e1f 92 SMART SM00966 8 51 7.6E-9 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_26705 5c32237db0158542bed0546030038e1f 92 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 4.2E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_26705 5c32237db0158542bed0546030038e1f 92 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 8.0E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_18650 67d9ea2fe30077ec5a979c11c1abebec 219 SUPERFAMILY SSF161098 13 201 9.68E-45 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_18650 67d9ea2fe30077ec5a979c11c1abebec 219 Gene3D G3DSA:1.10.3720.10 1 219 1.8E-57 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_18650 67d9ea2fe30077ec5a979c11c1abebec 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 2.4E-29 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I25_18650 67d9ea2fe30077ec5a979c11c1abebec 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 2.2E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 Gene3D G3DSA:1.20.58.560 240 338 8.0E-19 T 14-10-2018 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 SUPERFAMILY SSF81301 5 138 3.38E-40 T 14-10-2018 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 244 390 2.0E-43 T 14-10-2018 IPR032810 CCA-adding enzyme, C-terminal C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 168 226 1.2E-16 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 Gene3D G3DSA:3.30.460.10 1 143 4.0E-51 T 14-10-2018 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 Hamap MF_01263 CCA-adding enzyme [cca]. 1 395 42.195 T 14-10-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 Gene3D G3DSA:1.10.110.30 144 239 6.8E-28 T 14-10-2018 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 SUPERFAMILY SSF81891 140 393 6.02E-51 T 14-10-2018 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 Gene3D G3DSA:1.10.246.80 339 396 1.5E-23 T 14-10-2018 C2I25_03715 927cffce33d7855ddb0a2668fbc25fc6 397 Pfam PF01743 Poly A polymerase head domain 21 140 7.6E-34 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 C2I25_02155 df82160b3970b944b4af204f7e6768fb 211 Gene3D G3DSA:2.160.20.100 1 210 4.6E-52 T 14-10-2018 C2I25_02155 df82160b3970b944b4af204f7e6768fb 211 SUPERFAMILY SSF141571 32 210 5.23E-44 T 14-10-2018 C2I25_02155 df82160b3970b944b4af204f7e6768fb 211 Pfam PF13599 Pentapeptide repeats (9 copies) 67 143 1.6E-12 T 14-10-2018 IPR001646 Pentapeptide repeat C2I25_20815 ffb94c2570f61618efa69f7408d5feda 303 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 35 133 1.7E-7 T 14-10-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 C2I25_20815 ffb94c2570f61618efa69f7408d5feda 303 Gene3D G3DSA:1.10.340.30 128 250 9.5E-41 T 14-10-2018 C2I25_20815 ffb94c2570f61618efa69f7408d5feda 303 SMART SM00478 138 303 1.8E-27 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I25_20815 ffb94c2570f61618efa69f7408d5feda 303 SUPERFAMILY SSF48150 116 302 1.74E-44 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 C2I25_20815 ffb94c2570f61618efa69f7408d5feda 303 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 137 285 5.0E-15 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I25_20815 ffb94c2570f61618efa69f7408d5feda 303 Gene3D G3DSA:1.10.1670.40 104 300 9.5E-41 T 14-10-2018 C2I25_20815 ffb94c2570f61618efa69f7408d5feda 303 ProSitePatterns PS00516 Alkylbase DNA glycosidases alkA family signature. 234 258 - T 14-10-2018 IPR000035 Alkylbase DNA glycosidase, conserved site GO:0003905|GO:0006281 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 5 380 46.689 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 144 227 8.5E-39 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 SUPERFAMILY SSF55347 124 262 5.56E-58 T 14-10-2018 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 379 4.7E-160 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 Gene3D G3DSA:3.40.50.720 1 148 2.1E-50 T 14-10-2018 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 SUPERFAMILY SSF69055 289 381 1.44E-32 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 130 4.0E-43 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 SUPERFAMILY SSF51735 3 148 9.01E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 Gene3D G3DSA:1.10.1740.10 300 385 1.7E-29 T 14-10-2018 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 PIRSF PIRSF006205 2 385 7.6E-163 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_23075 45730a6a26a28c20279da86aeebd62f3 385 Pfam PF13288 DXP reductoisomerase C-terminal domain 259 375 5.7E-41 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_20465 a156d2f895afce44e2d404df6287a92d 307 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 299 19.169 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_20465 a156d2f895afce44e2d404df6287a92d 307 Gene3D G3DSA:3.30.2350.10 1 244 1.8E-90 T 14-10-2018 C2I25_20465 a156d2f895afce44e2d404df6287a92d 307 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 178 1.7E-57 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 C2I25_20465 a156d2f895afce44e2d404df6287a92d 307 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 216 7.0E-83 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_20465 a156d2f895afce44e2d404df6287a92d 307 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 4.9E-10 T 14-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 C2I25_20465 a156d2f895afce44e2d404df6287a92d 307 SUPERFAMILY SSF55120 1 221 1.41E-79 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_25815 57c2e44bb521f49ded2c44da894c3f62 305 SUPERFAMILY SSF56601 5 295 4.64E-67 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_25815 57c2e44bb521f49ded2c44da894c3f62 305 Gene3D G3DSA:3.40.710.10 2 288 4.6E-63 T 14-10-2018 C2I25_25815 57c2e44bb521f49ded2c44da894c3f62 305 Pfam PF00144 Beta-lactamase 18 282 1.2E-23 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_16000 712c8def0558e8dbf6eb1c2f0f2c346e 106 PIRSF PIRSF007103 6 106 4.6E-53 T 14-10-2018 IPR016508 Uncharacterised conserved protein UCP007103 C2I25_16000 712c8def0558e8dbf6eb1c2f0f2c346e 106 Pfam PF14154 Domain of unknown function (DUF4306) 12 98 1.4E-37 T 14-10-2018 IPR025440 Protein of unknown function DUF4306 C2I25_02225 43da3175f4b67574ba393e2840d231b6 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 3.2E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_02225 43da3175f4b67574ba393e2840d231b6 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_02225 43da3175f4b67574ba393e2840d231b6 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_02225 43da3175f4b67574ba393e2840d231b6 196 SUPERFAMILY SSF46689 6 81 3.64E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_02225 43da3175f4b67574ba393e2840d231b6 196 SUPERFAMILY SSF48498 77 191 5.13E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_02225 43da3175f4b67574ba393e2840d231b6 196 Gene3D G3DSA:1.10.357.10 1 195 2.8E-49 T 14-10-2018 C2I25_24610 7cabf754e5e3ec1217ed0bef5fe8046a 249 SUPERFAMILY SSF55781 70 244 2.09E-35 T 14-10-2018 C2I25_24610 7cabf754e5e3ec1217ed0bef5fe8046a 249 SUPERFAMILY SSF46785 2 77 4.28E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_24610 7cabf754e5e3ec1217ed0bef5fe8046a 249 SMART SM00346 2 94 1.4E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I25_24610 7cabf754e5e3ec1217ed0bef5fe8046a 249 Pfam PF09339 IclR helix-turn-helix domain 4 55 3.8E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I25_24610 7cabf754e5e3ec1217ed0bef5fe8046a 249 Pfam PF01614 Bacterial transcriptional regulator 123 240 2.0E-20 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal C2I25_24610 7cabf754e5e3ec1217ed0bef5fe8046a 249 Gene3D G3DSA:1.10.10.10 1 77 2.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24610 7cabf754e5e3ec1217ed0bef5fe8046a 249 Gene3D G3DSA:3.30.450.40 78 247 2.9E-41 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 SMART SM00487 23 220 3.4E-56 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 6 480 76.365 T 14-10-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 Pfam PF03880 DbpA RNA binding domain 407 477 3.7E-20 T 14-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 Pfam PF00271 Helicase conserved C-terminal domain 230 337 1.1E-29 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 Gene3D G3DSA:3.40.50.300 1 208 1.1E-72 T 14-10-2018 C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 Gene3D G3DSA:3.30.70.330 406 481 9.0E-29 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 Gene3D G3DSA:3.40.50.300 209 367 3.5E-51 T 14-10-2018 C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 Pfam PF00270 DEAD/DEAH box helicase 28 194 3.4E-47 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 SUPERFAMILY SSF52540 71 358 3.41E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11840 d8cbe49490cd9da7e6d52f3a514dcdc6 481 SMART SM00490 256 337 1.8E-35 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_06340 b2815037da324fef6106f0a433f10d96 314 Pfam PF01336 OB-fold nucleic acid binding domain 28 89 2.4E-6 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I25_06340 b2815037da324fef6106f0a433f10d96 314 SMART SM00471 156 288 2.4E-6 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_06340 b2815037da324fef6106f0a433f10d96 314 Gene3D G3DSA:1.10.3210.10 121 297 1.3E-11 T 14-10-2018 C2I25_06340 b2815037da324fef6106f0a433f10d96 314 Gene3D G3DSA:2.40.50.140 13 101 1.5E-5 T 14-10-2018 C2I25_06340 b2815037da324fef6106f0a433f10d96 314 Hamap MF_01427 3'-5' exoribonuclease YhaM [yhaM]. 1 313 62.044 T 14-10-2018 IPR020873 3'-5' exoribonuclease YhaM GO:0000175 C2I25_06340 b2815037da324fef6106f0a433f10d96 314 Pfam PF01966 HD domain 161 278 1.8E-10 T 14-10-2018 IPR006674 HD domain C2I25_06340 b2815037da324fef6106f0a433f10d96 314 SUPERFAMILY SSF109604 137 280 2.07E-15 T 14-10-2018 C2I25_06340 b2815037da324fef6106f0a433f10d96 314 SUPERFAMILY SSF50249 31 92 3.03E-5 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_21930 822b443b90becdefaab814fd9471e160 971 Gene3D G3DSA:2.60.120.380 856 971 5.3E-25 T 14-10-2018 C2I25_21930 822b443b90becdefaab814fd9471e160 971 Gene3D G3DSA:1.10.390.20 520 657 4.9E-56 T 14-10-2018 C2I25_21930 822b443b90becdefaab814fd9471e160 971 SMART SM00089 775 857 7.7E-25 T 14-10-2018 IPR022409 PKD/Chitinase domain C2I25_21930 822b443b90becdefaab814fd9471e160 971 SUPERFAMILY SSF49299 771 856 1.96E-23 T 14-10-2018 IPR035986 PKD domain superfamily C2I25_21930 822b443b90becdefaab814fd9471e160 971 Gene3D G3DSA:3.30.980.50 658 768 9.9E-46 T 14-10-2018 C2I25_21930 822b443b90becdefaab814fd9471e160 971 Pfam PF00801 PKD domain 796 847 6.0E-13 T 14-10-2018 IPR000601 PKD domain C2I25_21930 822b443b90becdefaab814fd9471e160 971 Gene3D G3DSA:2.60.40.10 769 855 8.1E-29 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_21930 822b443b90becdefaab814fd9471e160 971 Gene3D G3DSA:1.10.1740.190 376 519 1.7E-59 T 14-10-2018 C2I25_21930 822b443b90becdefaab814fd9471e160 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 529 544 2.3E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_21930 822b443b90becdefaab814fd9471e160 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 503 521 2.3E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_21930 822b443b90becdefaab814fd9471e160 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 466 482 2.3E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_21930 822b443b90becdefaab814fd9471e160 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 449 463 2.3E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_21930 822b443b90becdefaab814fd9471e160 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 163 181 2.3E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_21930 822b443b90becdefaab814fd9471e160 971 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 892 957 2.0E-5 T 14-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial C2I25_21930 822b443b90becdefaab814fd9471e160 971 SUPERFAMILY SSF89260 863 970 1.57E-29 T 14-10-2018 C2I25_21930 822b443b90becdefaab814fd9471e160 971 Pfam PF01752 Collagenase 302 630 1.2E-82 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_21930 822b443b90becdefaab814fd9471e160 971 Pfam PF08453 Peptidase family M9 N-terminal 97 278 1.3E-56 T 14-10-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 SUPERFAMILY SSF53850 93 273 2.64E-26 T 14-10-2018 C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 Gene3D G3DSA:3.40.190.10 164 266 7.9E-27 T 14-10-2018 C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 SUPERFAMILY SSF46785 7 93 1.32E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 Pfam PF03466 LysR substrate binding domain 120 274 3.7E-26 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 Gene3D G3DSA:3.40.190.10 98 273 7.9E-27 T 14-10-2018 C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_16040 61e28f869c36330019ee2d66adfd4ab0 285 Gene3D G3DSA:1.10.10.10 7 97 3.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19905 d59624b36b137c915e64ae919280fd08 310 PIRSF PIRSF004486 1 310 2.2E-110 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 C2I25_19905 d59624b36b137c915e64ae919280fd08 310 Gene3D G3DSA:3.40.50.150 4 308 1.6E-106 T 14-10-2018 C2I25_19905 d59624b36b137c915e64ae919280fd08 310 SUPERFAMILY SSF53335 4 309 1.5E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_19905 d59624b36b137c915e64ae919280fd08 310 SUPERFAMILY SSF81799 113 214 3.27E-36 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 C2I25_19905 d59624b36b137c915e64ae919280fd08 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 7.0E-130 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 C2I25_19905 d59624b36b137c915e64ae919280fd08 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 39.323 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 C2I25_19905 d59624b36b137c915e64ae919280fd08 310 Pfam PF01795 MraW methylase family 2 310 2.7E-134 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 C2I25_19905 d59624b36b137c915e64ae919280fd08 310 Gene3D G3DSA:1.10.150.170 111 215 1.6E-106 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 ProSitePatterns PS00786 5'-nucleotidase signature 2. 114 125 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 Pfam PF02872 5'-nucleotidase, C-terminal domain 342 490 3.5E-46 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 Pfam PF00149 Calcineurin-like phosphoesterase 41 269 9.9E-11 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 SUPERFAMILY SSF55816 339 528 7.19E-55 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 SUPERFAMILY SSF56300 33 341 2.59E-77 T 14-10-2018 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 PRINTS PR01607 Apyrase family signature 36 54 9.3E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 PRINTS PR01607 Apyrase family signature 394 417 9.3E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 PRINTS PR01607 Apyrase family signature 251 274 9.3E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 PRINTS PR01607 Apyrase family signature 222 239 9.3E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 PRINTS PR01607 Apyrase family signature 465 484 9.3E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 PRINTS PR01607 Apyrase family signature 277 297 9.3E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 Gene3D G3DSA:3.90.780.10 346 528 1.9E-58 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_24065 ea17aed417e0a189e4887890aaa3251c 529 Gene3D G3DSA:3.60.21.10 35 341 9.5E-82 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 5.2E-39 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 Gene3D G3DSA:1.20.140.10 235 380 2.7E-58 T 14-10-2018 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 2.3E-56 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 PIRSF PIRSF016578 2 378 1.4E-23 T 14-10-2018 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 1.7E-25 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 SUPERFAMILY SSF47203 229 378 4.49E-61 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 Gene3D G3DSA:2.40.110.10 122 234 6.3E-41 T 14-10-2018 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 Gene3D G3DSA:1.10.540.10 1 120 1.0E-45 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I25_27135 b32a536e603869c8bb18d86166ef6e7c 381 SUPERFAMILY SSF56645 2 243 1.1E-87 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I25_03335 b9188ab983ab6421efe69c611d0a3fc9 516 Pfam PF00474 Sodium:solute symporter family 33 434 3.3E-125 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_03335 b9188ab983ab6421efe69c611d0a3fc9 516 Gene3D G3DSA:1.20.1730.10 21 475 4.0E-68 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I25_03335 b9188ab983ab6421efe69c611d0a3fc9 516 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 416 436 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site C2I25_03335 b9188ab983ab6421efe69c611d0a3fc9 516 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 434 5.1E-92 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_03335 b9188ab983ab6421efe69c611d0a3fc9 516 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site C2I25_07380 16f169e09627314797abbbb5df329aa4 106 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 98 4.4E-36 T 14-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I25_07380 16f169e09627314797abbbb5df329aa4 106 PIRSF PIRSF000699 1 105 5.9E-38 T 14-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I25_07380 16f169e09627314797abbbb5df329aa4 106 SUPERFAMILY SSF46973 5 99 4.58E-35 T 14-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 C2I25_07380 16f169e09627314797abbbb5df329aa4 106 Gene3D G3DSA:1.20.58.280 2 104 1.2E-38 T 14-10-2018 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 SUPERFAMILY SSF52518 14 180 4.61E-34 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 SUPERFAMILY SSF52518 387 575 4.31E-33 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 437 553 2.1E-10 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 176 4.2E-37 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 SUPERFAMILY SSF52467 168 374 1.47E-7 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 PIRSF PIRSF004983 2 578 2.0E-217 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 Pfam PF16582 Middle domain of thiamine pyrophosphate 222 403 1.4E-18 T 14-10-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 Gene3D G3DSA:3.40.50.970 381 580 1.3E-65 T 14-10-2018 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 13 446 4.4E-154 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 Gene3D G3DSA:3.40.50.1220 200 380 1.3E-56 T 14-10-2018 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 Gene3D G3DSA:3.40.50.970 1 175 4.3E-68 T 14-10-2018 C2I25_14895 a8f1d51a62c11edd07ed9cf217b96f16 584 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 5 571 35.897 T 14-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 C2I25_15450 23bece496eb5285e03836c88b1170a27 170 Gene3D G3DSA:2.160.10.10 1 170 5.1E-75 T 14-10-2018 C2I25_15450 23bece496eb5285e03836c88b1170a27 170 SUPERFAMILY SSF51161 2 168 6.24E-51 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_15450 23bece496eb5285e03836c88b1170a27 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 5.2E-8 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_15450 23bece496eb5285e03836c88b1170a27 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 9 44 2.9E-5 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_26410 1f6ddb7b9c9bf6eea6e2a786c15f0c07 226 Gene3D G3DSA:3.40.50.1860 102 212 5.6E-74 T 14-10-2018 C2I25_26410 1f6ddb7b9c9bf6eea6e2a786c15f0c07 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 221 2.6E-49 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_26410 1f6ddb7b9c9bf6eea6e2a786c15f0c07 226 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 190 200 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_26410 1f6ddb7b9c9bf6eea6e2a786c15f0c07 226 SUPERFAMILY SSF53681 1 112 2.83E-27 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_26410 1f6ddb7b9c9bf6eea6e2a786c15f0c07 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 225 2.1E-63 T 14-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 C2I25_26410 1f6ddb7b9c9bf6eea6e2a786c15f0c07 226 SUPERFAMILY SSF53681 116 225 2.29E-32 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_26410 1f6ddb7b9c9bf6eea6e2a786c15f0c07 226 Gene3D G3DSA:3.40.50.1860 4 220 5.6E-74 T 14-10-2018 C2I25_23335 2ee9016ad93e4816e5841c5d739a4fde 79 Pfam PF13396 Phospholipase_D-nuclease N-terminal 31 73 1.3E-11 T 14-10-2018 IPR027379 Cardiolipin synthase N-terminal C2I25_10420 cc8717e491ceb45f090490893820e3c6 549 SUPERFAMILY SSF88713 209 402 1.14E-8 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_10420 cc8717e491ceb45f090490893820e3c6 549 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 213 474 3.6E-67 T 14-10-2018 IPR018763 Protein of unknown function DUF2334 C2I25_07060 03628fd2b41e96bdda3418ce2dea8731 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 226 2.2E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_07060 03628fd2b41e96bdda3418ce2dea8731 232 Gene3D G3DSA:1.10.3720.10 18 229 1.1E-53 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07060 03628fd2b41e96bdda3418ce2dea8731 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 121 1.1E-32 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I25_07060 03628fd2b41e96bdda3418ce2dea8731 232 SUPERFAMILY SSF161098 25 227 7.19E-46 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_09340 4beff19817580f4ae457b9bb9f75aa3c 83 SUPERFAMILY SSF47413 21 81 1.01E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_09340 4beff19817580f4ae457b9bb9f75aa3c 83 Gene3D G3DSA:1.10.260.40 20 83 6.7E-26 T 14-10-2018 C2I25_09340 4beff19817580f4ae457b9bb9f75aa3c 83 SMART SM00530 23 78 2.3E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_09340 4beff19817580f4ae457b9bb9f75aa3c 83 Pfam PF01381 Helix-turn-helix 24 78 3.3E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_18550 b9e0dba87804948a026cae6d83384263 508 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 152 297 3.5E-6 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 SMART SM00478 46 197 4.1E-57 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 42 176 3.2E-21 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 Gene3D G3DSA:1.10.1670.10 17 220 2.6E-89 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 Pfam PF14815 NUDIX domain 243 356 4.9E-19 T 14-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 SUPERFAMILY SSF55811 236 357 1.62E-24 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 Gene3D G3DSA:3.90.79.10 237 362 9.0E-27 T 14-10-2018 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 Gene3D G3DSA:1.10.340.30 28 139 2.6E-89 T 14-10-2018 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 SUPERFAMILY SSF48150 11 229 6.91E-76 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 SMART SM00525 198 218 0.0023 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 C2I25_08985 5ee58e6d3bd0bc7fe94314fe551abf39 365 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 13 282 7.4E-110 T 14-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 Gene3D G3DSA:3.30.870.10 39 222 6.8E-44 T 14-10-2018 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 SUPERFAMILY SSF56024 190 380 2.92E-44 T 14-10-2018 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 SMART SM00155 138 165 5.8E-4 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 SMART SM00155 310 337 2.3E-6 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 23 393 1.4E-103 T 14-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 SUPERFAMILY SSF56024 17 228 2.2E-49 T 14-10-2018 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 Gene3D G3DSA:3.30.870.10 223 370 2.9E-28 T 14-10-2018 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 Pfam PF13091 PLD-like domain 238 364 1.5E-30 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 Pfam PF13091 PLD-like domain 57 198 2.4E-16 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 PIRSF PIRSF000850 297 377 31.0 T 14-10-2018 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 PIRSF PIRSF000850 26 115 0.42 T 14-10-2018 C2I25_12435 4a8821cdc08ce15468d56e7d15d30de2 397 PIRSF PIRSF000850 202 310 2.7E-4 T 14-10-2018 C2I25_16495 3967e2936f9e5bb2811e6433b4b29252 69 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 1.5E-36 T 14-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 C2I25_16495 3967e2936f9e5bb2811e6433b4b29252 69 Pfam PF14098 Small, acid-soluble spore protein I 3 67 2.8E-30 T 14-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 C2I25_16495 3967e2936f9e5bb2811e6433b4b29252 69 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 22.058 T 14-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Gene3D G3DSA:3.30.559.30 192 445 2.3E-38 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 SUPERFAMILY SSF52777 1049 1218 4.0E-27 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1343 1491 2.7E-41 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Gene3D G3DSA:3.30.559.30 1210 1473 8.2E-52 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Gene3D G3DSA:1.10.1200.10 957 1029 3.9E-16 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 PIRSF PIRSF001617 1105 1245 230.0 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 PIRSF PIRSF001617 901 1064 2.4E-9 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 PIRSF PIRSF001617 589 827 4.6E-19 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 PIRSF PIRSF001617 821 909 1.6E-19 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 PIRSF PIRSF001617 188 566 5.2E-20 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Gene3D G3DSA:3.30.559.10 10 191 3.3E-36 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Pfam PF00501 AMP-binding enzyme 459 856 1.3E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Pfam PF13193 AMP-binding enzyme C-terminal domain 864 937 9.1E-7 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Gene3D G3DSA:3.30.300.30 851 953 1.2E-29 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Pfam PF00550 Phosphopantetheine attachment site 961 1023 2.0E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 SUPERFAMILY SSF56801 417 972 3.92E-138 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 SUPERFAMILY SSF52777 9 166 1.89E-30 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 ProSitePatterns PS00455 Putative AMP-binding domain signature. 601 612 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Gene3D G3DSA:3.40.50.12780 446 850 1.5E-119 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 480 880 3.6E-126 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 ProSitePatterns PS00012 Phosphopantetheine attachment site. 983 998 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Pfam PF00668 Condensation domain 7 437 9.0E-87 T 14-10-2018 IPR001242 Condensation domain C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Pfam PF00668 Condensation domain 1049 1483 6.2E-76 T 14-10-2018 IPR001242 Condensation domain C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 SUPERFAMILY SSF47336 955 1023 5.23E-13 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 SUPERFAMILY SSF52777 189 422 2.67E-33 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 SUPERFAMILY SSF52777 1228 1471 2.11E-30 T 14-10-2018 C2I25_02060 061379b3a6cf8318f255ad2260c645d2 1494 Gene3D G3DSA:3.30.559.10 1030 1208 1.4E-37 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_22720 621ec6d201f2805eb60be56ed4afc367 353 Gene3D G3DSA:3.30.360.10 123 353 3.4E-68 T 14-10-2018 C2I25_22720 621ec6d201f2805eb60be56ed4afc367 353 Gene3D G3DSA:1.10.3270.10 48 122 1.5E-25 T 14-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 C2I25_22720 621ec6d201f2805eb60be56ed4afc367 353 Gene3D G3DSA:1.10.3270.10 1 47 3.3E-11 T 14-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 C2I25_22720 621ec6d201f2805eb60be56ed4afc367 353 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 120 1.7E-24 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I25_22720 621ec6d201f2805eb60be56ed4afc367 353 SUPERFAMILY SSF55347 131 279 2.18E-17 T 14-10-2018 C2I25_22720 621ec6d201f2805eb60be56ed4afc367 353 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 229 3.3E-6 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 C2I25_22720 621ec6d201f2805eb60be56ed4afc367 353 SUPERFAMILY SSF51735 3 158 3.71E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_26670 0665d0fdae3c0e16c90df285fe47c78b 268 Pfam PF13704 Glycosyl transferase family 2 16 101 1.4E-7 T 14-10-2018 C2I25_08280 8ad1c9456d0b60d52a5d93a7ad1cd3eb 476 Gene3D G3DSA:1.20.1740.10 7 474 3.3E-70 T 14-10-2018 C2I25_08280 8ad1c9456d0b60d52a5d93a7ad1cd3eb 476 Pfam PF00324 Amino acid permease 17 456 2.3E-120 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I25_08280 8ad1c9456d0b60d52a5d93a7ad1cd3eb 476 PIRSF PIRSF006060 1 475 1.2E-85 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_08280 8ad1c9456d0b60d52a5d93a7ad1cd3eb 476 ProSitePatterns PS00218 Amino acid permeases signature. 42 73 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 38.823 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 PIRSF PIRSF001438 1 309 3.0E-121 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 5.7E-18 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 6.1E-79 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 7.3E-49 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 7.3E-49 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 7.3E-49 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 7.3E-49 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 7.3E-49 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 SUPERFAMILY SSF53850 2 218 8.54E-82 T 14-10-2018 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 2.0E-111 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 Gene3D G3DSA:3.40.190.10 101 201 3.2E-84 T 14-10-2018 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 Gene3D G3DSA:3.30.160.40 220 303 2.6E-27 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 Gene3D G3DSA:3.40.190.10 4 209 3.2E-84 T 14-10-2018 C2I25_16960 fc7b09f9fdb66715f6a14c3690855798 309 SUPERFAMILY SSF54782 219 304 3.4E-22 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_27710 9e52162940eba66be244da52b54d90f6 297 Gene3D G3DSA:3.30.420.40 109 271 5.2E-65 T 14-10-2018 C2I25_27710 9e52162940eba66be244da52b54d90f6 297 SUPERFAMILY SSF53067 110 296 9.25E-41 T 14-10-2018 C2I25_27710 9e52162940eba66be244da52b54d90f6 297 SUPERFAMILY SSF53067 1 107 5.4E-19 T 14-10-2018 C2I25_27710 9e52162940eba66be244da52b54d90f6 297 Gene3D G3DSA:3.30.420.40 5 108 5.2E-65 T 14-10-2018 C2I25_27710 9e52162940eba66be244da52b54d90f6 297 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 255 1.4E-21 T 14-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 C2I25_18350 9daa8c01407c8566a745a960d717d6c7 308 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 26 292 2.8E-122 T 14-10-2018 IPR014217 Sporulation stage III, protein AA C2I25_18350 9daa8c01407c8566a745a960d717d6c7 308 SMART SM00382 133 282 1.8E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_18350 9daa8c01407c8566a745a960d717d6c7 308 Gene3D G3DSA:3.40.50.300 114 269 1.9E-22 T 14-10-2018 C2I25_18350 9daa8c01407c8566a745a960d717d6c7 308 SUPERFAMILY SSF52540 23 260 4.96E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11570 17dd42d2e3240d870b92a1c97be5f5c1 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 185 2.0E-90 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11570 17dd42d2e3240d870b92a1c97be5f5c1 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 14-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11570 17dd42d2e3240d870b92a1c97be5f5c1 196 Pfam PF01174 SNO glutamine amidotransferase family 6 188 5.9E-72 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11570 17dd42d2e3240d870b92a1c97be5f5c1 196 Gene3D G3DSA:3.40.50.880 1 195 7.5E-70 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_11570 17dd42d2e3240d870b92a1c97be5f5c1 196 SUPERFAMILY SSF52317 2 189 3.82E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_11570 17dd42d2e3240d870b92a1c97be5f5c1 196 PIRSF PIRSF005639 1 191 9.0E-74 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11570 17dd42d2e3240d870b92a1c97be5f5c1 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 37.25 T 14-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 Gene3D G3DSA:1.20.1260.10 1 146 9.3E-58 T 14-10-2018 IPR012347 Ferritin-like C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 7.5E-17 T 14-10-2018 IPR002177 DNA-binding protein Dps C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 7.5E-17 T 14-10-2018 IPR002177 DNA-binding protein Dps C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 7.5E-17 T 14-10-2018 IPR002177 DNA-binding protein Dps C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 Pfam PF00210 Ferritin-like domain 6 146 3.0E-36 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 SUPERFAMILY SSF47240 3 144 3.64E-50 T 14-10-2018 IPR009078 Ferritin-like superfamily C2I25_13820 afdcfd441fa350833eb45c61bdfc8652 146 PIRSF PIRSF005900 1 146 3.2E-51 T 14-10-2018 IPR002177 DNA-binding protein Dps C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 PIRSF PIRSF002599 1 66 2.1E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 SMART SM00357 3 66 7.2E-31 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 14-10-2018 IPR019844 Cold-shock conserved site C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 PRINTS PR00050 Cold shock protein signature 24 33 1.8E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 PRINTS PR00050 Cold shock protein signature 39 57 1.8E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 PRINTS PR00050 Cold shock protein signature 4 19 1.8E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 8.9E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 Gene3D G3DSA:2.40.50.140 1 66 7.7E-31 T 14-10-2018 C2I25_21885 ecf94cf431c6c2a45007e600117fa77d 66 SUPERFAMILY SSF50249 1 64 1.14E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_12545 5f843c89963db3bbff0284fd2ff64f7b 346 PIRSF PIRSF004930 1 346 1.9E-135 T 14-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 C2I25_12545 5f843c89963db3bbff0284fd2ff64f7b 346 SUPERFAMILY SSF55821 19 214 3.97E-68 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily C2I25_12545 5f843c89963db3bbff0284fd2ff64f7b 346 Gene3D G3DSA:3.40.50.11030 221 346 3.2E-41 T 14-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily C2I25_12545 5f843c89963db3bbff0284fd2ff64f7b 346 Gene3D G3DSA:3.90.870.10 7 218 3.3E-85 T 14-10-2018 C2I25_12545 5f843c89963db3bbff0284fd2ff64f7b 346 Pfam PF03481 Putative GTP-binding controlling metal-binding 204 340 8.9E-29 T 14-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain C2I25_12545 5f843c89963db3bbff0284fd2ff64f7b 346 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 20 213 2.3E-65 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 C2I25_12545 5f843c89963db3bbff0284fd2ff64f7b 346 Pfam PF01300 Telomere recombination 27 202 7.4E-58 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 Gene3D G3DSA:1.20.140.160 107 254 2.6E-31 T 14-10-2018 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 Pfam PF04545 Sigma-70, region 4 205 252 3.0E-14 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 Pfam PF04542 Sigma-70 region 2 35 104 1.4E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 Pfam PF04539 Sigma-70 region 3 117 188 8.0E-15 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 29 253 4.6E-86 T 14-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 SUPERFAMILY SSF88659 182 253 4.3E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 253 1.5E-32 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 Gene3D G3DSA:1.20.120.1810 1 103 2.9E-18 T 14-10-2018 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 2 255 1.1E-142 T 14-10-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 SUPERFAMILY SSF88659 108 178 2.92E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 SUPERFAMILY SSF88946 11 104 3.14E-27 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 PRINTS PR00046 Major sigma-70 factor signature 224 239 3.3E-7 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 PRINTS PR00046 Major sigma-70 factor signature 59 72 3.3E-7 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 PRINTS PR00046 Major sigma-70 factor signature 207 219 3.3E-7 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_06430 5092aad5af7f0f9d1cfcfa5af8e32f25 258 PRINTS PR00046 Major sigma-70 factor signature 239 250 3.3E-7 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_18935 74901c8d83be44f0108a4d6b4392766b 439 Pfam PF03553 Na+/H+ antiporter family 151 433 1.1E-67 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I25_18935 74901c8d83be44f0108a4d6b4392766b 439 PRINTS PR00173 Glutamate-aspartate symporter signature 372 391 9.5E-5 T 14-10-2018 C2I25_18935 74901c8d83be44f0108a4d6b4392766b 439 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 9.5E-5 T 14-10-2018 C2I25_18935 74901c8d83be44f0108a4d6b4392766b 439 Pfam PF13726 Na+-H+ antiporter family 2 88 6.6E-33 T 14-10-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal C2I25_03690 b4efcee4f8305a244782cce47bf1f14d 282 Pfam PF02569 Pantoate-beta-alanine ligase 2 277 1.8E-99 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 C2I25_03690 b4efcee4f8305a244782cce47bf1f14d 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 38.234 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 C2I25_03690 b4efcee4f8305a244782cce47bf1f14d 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 73 2.7E-7 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I25_03690 b4efcee4f8305a244782cce47bf1f14d 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 1.1E-108 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 C2I25_03690 b4efcee4f8305a244782cce47bf1f14d 282 SUPERFAMILY SSF52374 1 280 1.66E-103 T 14-10-2018 C2I25_03690 b4efcee4f8305a244782cce47bf1f14d 282 Gene3D G3DSA:3.40.50.620 1 177 4.3E-74 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_03690 b4efcee4f8305a244782cce47bf1f14d 282 Gene3D G3DSA:3.30.1300.10 178 277 4.8E-31 T 14-10-2018 C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 2.6E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 2.6E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 2.6E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 2.6E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 2.6E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 6.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 6.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 6.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 SUPERFAMILY SSF51735 2 237 3.31E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 Gene3D G3DSA:3.40.50.720 1 240 6.6E-64 T 14-10-2018 C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_06080 977f158d08d85cfb867fe455e4beb942 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 236 2.4E-55 T 14-10-2018 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 Gene3D G3DSA:3.90.170.10 265 429 2.2E-71 T 14-10-2018 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 Gene3D G3DSA:1.10.300.10 100 199 7.4E-109 T 14-10-2018 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 7.6E-192 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 SMART SM00788 3 422 7.5E-293 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 SUPERFAMILY SSF52540 1 427 2.23E-176 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 14-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 Gene3D G3DSA:3.40.440.10 5 252 7.4E-109 T 14-10-2018 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.1E-184 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 211.042 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I25_11755 b3751cfd8a9733dff24b181a253e522e 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I25_13785 fdbe963cd1e4c826e37fc8b79e9c5bed 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 1.1E-57 T 14-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I25_13785 fdbe963cd1e4c826e37fc8b79e9c5bed 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 3.6E-21 T 14-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I25_24490 d667091135d55bf22b58bee2d2e7e5dc 105 Pfam PF03551 Transcriptional regulator PadR-like family 23 86 1.5E-13 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_24490 d667091135d55bf22b58bee2d2e7e5dc 105 SUPERFAMILY SSF46785 10 100 1.05E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_24490 d667091135d55bf22b58bee2d2e7e5dc 105 Gene3D G3DSA:1.10.10.10 5 103 1.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24300 8ff981bbc193d98d517b333ac74dae5d 488 Pfam PF00324 Amino acid permease 29 478 7.3E-136 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I25_24300 8ff981bbc193d98d517b333ac74dae5d 488 PIRSF PIRSF006060 2 481 1.6E-85 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_24300 8ff981bbc193d98d517b333ac74dae5d 488 Gene3D G3DSA:1.20.1740.10 20 483 7.7E-61 T 14-10-2018 C2I25_24300 8ff981bbc193d98d517b333ac74dae5d 488 ProSitePatterns PS00218 Amino acid permeases signature. 54 85 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 44.518 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 1.6E-107 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 Pfam PF06827 Zinc finger found in FPG and IleRS 246 275 2.4E-10 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 SUPERFAMILY SSF57716 222 274 1.49E-17 T 14-10-2018 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 SUPERFAMILY SSF81624 2 139 1.7E-42 T 14-10-2018 IPR035937 MutM-like, N-terminal C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 SMART SM01232 134 226 8.5E-45 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 SUPERFAMILY SSF46946 134 223 2.09E-29 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 224 5.8E-29 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 Gene3D G3DSA:1.10.8.50 136 275 1.5E-48 T 14-10-2018 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 SMART SM00898 2 118 1.2E-51 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 2.6E-34 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 C2I25_16375 8be02d16fc6ae049b2b0575647b22706 276 Gene3D G3DSA:3.20.190.10 1 135 2.8E-41 T 14-10-2018 IPR035937 MutM-like, N-terminal C2I25_03730 ef3eea7e2672dbf0e21af0cbd1b11982 131 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 1 120 6.7E-58 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 C2I25_03730 ef3eea7e2672dbf0e21af0cbd1b11982 131 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 34.102 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 C2I25_03730 ef3eea7e2672dbf0e21af0cbd1b11982 131 SMART SM00851 14 107 2.5E-23 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I25_03730 ef3eea7e2672dbf0e21af0cbd1b11982 131 Gene3D G3DSA:3.40.50.1380 1 131 2.8E-56 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I25_03730 ef3eea7e2672dbf0e21af0cbd1b11982 131 Pfam PF02142 MGS-like domain 15 107 1.7E-17 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I25_03730 ef3eea7e2672dbf0e21af0cbd1b11982 131 SUPERFAMILY SSF52335 1 128 4.97E-52 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I25_03730 ef3eea7e2672dbf0e21af0cbd1b11982 131 PIRSF PIRSF006614 1 131 1.9E-61 T 14-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 C2I25_03730 ef3eea7e2672dbf0e21af0cbd1b11982 131 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 61 - T 14-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 SUPERFAMILY SSF50129 1 93 1.7E-35 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 PRINTS PR00297 10kDa chaperonin signature 2 17 1.8E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 PRINTS PR00297 10kDa chaperonin signature 24 45 1.8E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 PRINTS PR00297 10kDa chaperonin signature 59 71 1.8E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 PRINTS PR00297 10kDa chaperonin signature 80 93 1.8E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 2.9E-36 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 SMART SM00883 1 93 5.2E-58 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.103 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I25_10110 371a8eb92091ca4882053ab0b8a32e8d 94 Gene3D G3DSA:2.30.33.40 1 93 1.5E-38 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 C2I25_07715 c3022bc05fbb297f331a1adfa95922a8 369 Pfam PF01266 FAD dependent oxidoreductase 6 351 4.1E-75 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I25_07715 c3022bc05fbb297f331a1adfa95922a8 369 SUPERFAMILY SSF54373 226 310 1.44E-18 T 14-10-2018 C2I25_07715 c3022bc05fbb297f331a1adfa95922a8 369 Gene3D G3DSA:3.30.9.10 92 311 2.9E-108 T 14-10-2018 C2I25_07715 c3022bc05fbb297f331a1adfa95922a8 369 Gene3D G3DSA:3.50.50.60 6 352 2.9E-108 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_07715 c3022bc05fbb297f331a1adfa95922a8 369 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 356 1.5E-130 T 14-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 C2I25_07715 c3022bc05fbb297f331a1adfa95922a8 369 SUPERFAMILY SSF51905 4 368 8.42E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_07655 cecadf6adda5bd07f53e716749bfc142 193 Pfam PF02669 K+-transporting ATPase, c chain 10 189 2.3E-72 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 C2I25_07655 cecadf6adda5bd07f53e716749bfc142 193 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 191 33.322 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 C2I25_07655 cecadf6adda5bd07f53e716749bfc142 193 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 8 190 2.9E-59 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 C2I25_07655 cecadf6adda5bd07f53e716749bfc142 193 PIRSF PIRSF001296 4 193 9.9E-79 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 C2I25_00885 bee27c6767f75f4c488b10752da1e00e 670 SMART SM00220 9 266 8.3E-57 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_00885 bee27c6767f75f4c488b10752da1e00e 670 Pfam PF00069 Protein kinase domain 9 259 2.2E-52 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_00885 bee27c6767f75f4c488b10752da1e00e 670 Gene3D G3DSA:1.10.510.10 2 312 6.5E-69 T 14-10-2018 C2I25_00885 bee27c6767f75f4c488b10752da1e00e 670 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 36 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 C2I25_00885 bee27c6767f75f4c488b10752da1e00e 670 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 C2I25_00885 bee27c6767f75f4c488b10752da1e00e 670 SUPERFAMILY SSF56112 6 271 3.24E-71 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_10770 f7b21159537eb672460d1cc7bc1ed686 254 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 53 243 1.1E-84 T 14-10-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB C2I25_10770 f7b21159537eb672460d1cc7bc1ed686 254 Pfam PF01522 Polysaccharide deacetylase 52 175 9.6E-26 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_10770 f7b21159537eb672460d1cc7bc1ed686 254 Gene3D G3DSA:3.20.20.370 47 254 1.6E-59 T 14-10-2018 C2I25_10770 f7b21159537eb672460d1cc7bc1ed686 254 SUPERFAMILY SSF88713 14 243 6.67E-54 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_07650 ce2b226eac5acc6eb7fcd47f173c5cba 384 Gene3D G3DSA:3.40.50.300 27 237 3.3E-88 T 14-10-2018 C2I25_07650 ce2b226eac5acc6eb7fcd47f173c5cba 384 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 30 237 8.5E-89 T 14-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 C2I25_07650 ce2b226eac5acc6eb7fcd47f173c5cba 384 SUPERFAMILY SSF52402 254 372 2.02E-14 T 14-10-2018 C2I25_07650 ce2b226eac5acc6eb7fcd47f173c5cba 384 Pfam PF00582 Universal stress protein family 254 372 1.2E-10 T 14-10-2018 IPR006016 UspA C2I25_07650 ce2b226eac5acc6eb7fcd47f173c5cba 384 Gene3D G3DSA:3.40.50.620 252 380 4.0E-11 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_09335 4e287a697b7d7fbfd8f8946cc05702bc 427 Gene3D G3DSA:1.20.1250.20 226 416 2.8E-19 T 14-10-2018 C2I25_09335 4e287a697b7d7fbfd8f8946cc05702bc 427 Gene3D G3DSA:1.20.1250.20 11 203 5.5E-7 T 14-10-2018 C2I25_09335 4e287a697b7d7fbfd8f8946cc05702bc 427 SUPERFAMILY SSF103473 16 413 1.7E-37 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_09335 4e287a697b7d7fbfd8f8946cc05702bc 427 Pfam PF11700 Vacuole effluxer Atg22 like 138 413 2.2E-49 T 14-10-2018 IPR024671 Autophagy-related protein 22-like C2I25_09335 4e287a697b7d7fbfd8f8946cc05702bc 427 Pfam PF11700 Vacuole effluxer Atg22 like 48 131 2.2E-9 T 14-10-2018 IPR024671 Autophagy-related protein 22-like C2I25_23420 04bc82cc9286e50d43ac46304fa5171e 280 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 202 261 2.8E-15 T 14-10-2018 IPR006343 DnaD domain C2I25_23420 04bc82cc9286e50d43ac46304fa5171e 280 SUPERFAMILY SSF158499 201 261 1.14E-14 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_23420 04bc82cc9286e50d43ac46304fa5171e 280 Gene3D G3DSA:1.10.10.630 198 267 3.4E-12 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_23420 04bc82cc9286e50d43ac46304fa5171e 280 Pfam PF07261 Replication initiation and membrane attachment 202 261 1.3E-10 T 14-10-2018 IPR006343 DnaD domain C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 Gene3D G3DSA:3.40.190.290 91 287 1.2E-42 T 14-10-2018 C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 SUPERFAMILY SSF46785 1 111 7.34E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.2E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 SUPERFAMILY SSF53850 89 288 2.53E-36 T 14-10-2018 C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 Gene3D G3DSA:1.10.10.10 1 88 5.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_23790 14a74d160ba821bb3db304d8f50868e1 290 Pfam PF03466 LysR substrate binding domain 90 287 1.8E-38 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_12310 2a919a266331959434e0ee3045bed559 387 PRINTS PR01035 Tetracycline resistance protein signature 18 34 3.6E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_12310 2a919a266331959434e0ee3045bed559 387 PRINTS PR01035 Tetracycline resistance protein signature 159 179 3.6E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_12310 2a919a266331959434e0ee3045bed559 387 PRINTS PR01035 Tetracycline resistance protein signature 131 153 3.6E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_12310 2a919a266331959434e0ee3045bed559 387 Pfam PF07690 Major Facilitator Superfamily 13 341 7.6E-43 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_12310 2a919a266331959434e0ee3045bed559 387 Gene3D G3DSA:1.20.1250.20 3 373 2.4E-62 T 14-10-2018 C2I25_12310 2a919a266331959434e0ee3045bed559 387 SUPERFAMILY SSF103473 1 379 2.75E-65 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_05245 966f57542fa1b3a57297d826e8facca9 131 Pfam PF06713 Bacterial PH domain 53 125 2.3E-23 T 14-10-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 SMART SM00387 373 484 1.9E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 SMART SM00388 262 328 1.9E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 Gene3D G3DSA:1.20.1480.50 174 266 1.2E-10 T 14-10-2018 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 3.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 3.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 3.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 3.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 327 1.1E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 483 1.6E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 SUPERFAMILY SSF158472 209 257 2.62E-6 T 14-10-2018 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 SUPERFAMILY SSF55874 318 483 1.17E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 Gene3D G3DSA:3.30.565.10 332 484 5.4E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 SMART SM00304 209 261 6.3E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 Gene3D G3DSA:1.10.287.130 267 324 4.0E-14 T 14-10-2018 C2I25_08565 333428e9577bdd4dffa4ea73987d763a 484 SUPERFAMILY SSF47384 246 329 4.51E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_27790 eafded03323fd4c5ebc03d825a8b73ce 363 Pfam PF13799 Domain of unknown function (DUF4183) 290 359 2.3E-20 T 14-10-2018 IPR025237 Domain of unknown function DUF4183 C2I25_27790 eafded03323fd4c5ebc03d825a8b73ce 363 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 14 32 2.1E-6 T 14-10-2018 IPR021201 Leader peptide, exosporium C2I25_27790 eafded03323fd4c5ebc03d825a8b73ce 363 Pfam PF01391 Collagen triple helix repeat (20 copies) 181 231 9.3E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_27790 eafded03323fd4c5ebc03d825a8b73ce 363 Pfam PF01391 Collagen triple helix repeat (20 copies) 220 276 6.4E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_27790 eafded03323fd4c5ebc03d825a8b73ce 363 Pfam PF01391 Collagen triple helix repeat (20 copies) 34 92 4.9E-9 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_14135 30f793cfb003005292a487c18c0754a8 121 Gene3D G3DSA:3.40.30.10 1 116 5.2E-47 T 14-10-2018 C2I25_14135 30f793cfb003005292a487c18c0754a8 121 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 117 2.6E-34 T 14-10-2018 IPR006504 Transcriptional regulator Spx/MgsR C2I25_14135 30f793cfb003005292a487c18c0754a8 121 Pfam PF03960 ArsC family 10 114 1.7E-16 T 14-10-2018 IPR006660 Arsenate reductase-like C2I25_14135 30f793cfb003005292a487c18c0754a8 121 SUPERFAMILY SSF52833 2 117 7.0E-37 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_01935 c2f5f9e8777436a2700a321f4446cb64 107 SUPERFAMILY SSF69118 8 103 1.12E-24 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I25_01935 c2f5f9e8777436a2700a321f4446cb64 107 Gene3D G3DSA:1.20.1290.10 4 107 9.0E-29 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I25_01935 c2f5f9e8777436a2700a321f4446cb64 107 Pfam PF02627 Carboxymuconolactone decarboxylase family 19 100 9.3E-20 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I25_16535 8767a1817904cff5bde7c7e6bd0aa94c 311 SUPERFAMILY SSF53098 96 308 4.55E-53 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_16535 8767a1817904cff5bde7c7e6bd0aa94c 311 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 6 302 5.5E-91 T 14-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 C2I25_16535 8767a1817904cff5bde7c7e6bd0aa94c 311 Gene3D G3DSA:3.30.420.10 95 311 1.6E-81 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_16535 8767a1817904cff5bde7c7e6bd0aa94c 311 PIRSF PIRSF037748 1 311 5.3E-123 T 14-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 C2I25_16535 8767a1817904cff5bde7c7e6bd0aa94c 311 Gene3D G3DSA:3.30.310.10 1 87 9.5E-29 T 14-10-2018 IPR012295 TBP domain superfamily C2I25_16535 8767a1817904cff5bde7c7e6bd0aa94c 311 Pfam PF01351 Ribonuclease HII 98 303 3.1E-48 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain C2I25_16535 8767a1817904cff5bde7c7e6bd0aa94c 311 Hamap MF_00053 Ribonuclease HIII [rnhC]. 2 310 37.242 T 14-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 C2I25_16535 8767a1817904cff5bde7c7e6bd0aa94c 311 Pfam PF11858 Domain of unknown function (DUF3378) 5 78 1.9E-27 T 14-10-2018 IPR024568 Ribonuclease HIII, N-terminal C2I25_09135 af6c16e62cf977702a58f5643b15b7a3 424 Pfam PF01546 Peptidase family M20/M25/M40 86 417 2.6E-30 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_09135 af6c16e62cf977702a58f5643b15b7a3 424 SUPERFAMILY SSF53187 6 421 6.01E-61 T 14-10-2018 C2I25_09135 af6c16e62cf977702a58f5643b15b7a3 424 Gene3D G3DSA:3.40.630.10 9 193 1.1E-43 T 14-10-2018 C2I25_09135 af6c16e62cf977702a58f5643b15b7a3 424 Gene3D G3DSA:3.40.630.10 322 424 5.1E-14 T 14-10-2018 C2I25_09135 af6c16e62cf977702a58f5643b15b7a3 424 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 21 411 9.1E-119 T 14-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase C2I25_09135 af6c16e62cf977702a58f5643b15b7a3 424 SUPERFAMILY SSF55031 215 308 5.83E-11 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_09135 af6c16e62cf977702a58f5643b15b7a3 424 Pfam PF07687 Peptidase dimerisation domain 188 309 5.0E-31 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_09135 af6c16e62cf977702a58f5643b15b7a3 424 Gene3D G3DSA:3.30.70.360 194 321 5.5E-29 T 14-10-2018 C2I25_00180 1bb416f5eb633133a728377d878e2fd4 291 SUPERFAMILY SSF56752 5 282 2.35E-78 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 C2I25_00180 1bb416f5eb633133a728377d878e2fd4 291 Gene3D G3DSA:3.20.10.10 129 286 1.6E-56 T 14-10-2018 C2I25_00180 1bb416f5eb633133a728377d878e2fd4 291 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 9 284 8.8E-94 T 14-10-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 C2I25_00180 1bb416f5eb633133a728377d878e2fd4 291 Gene3D G3DSA:3.30.470.10 1 126 7.5E-32 T 14-10-2018 C2I25_00180 1bb416f5eb633133a728377d878e2fd4 291 Pfam PF01063 Amino-transferase class IV 37 259 3.6E-50 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 C2I25_00180 1bb416f5eb633133a728377d878e2fd4 291 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 C2I25_15635 12b305e927c7c4757ef244e0da7fe1af 161 Pfam PF01967 MoaC family 15 152 5.5E-53 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15635 12b305e927c7c4757ef244e0da7fe1af 161 Gene3D G3DSA:3.30.70.640 1 161 1.3E-69 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15635 12b305e927c7c4757ef244e0da7fe1af 161 SUPERFAMILY SSF55040 11 157 1.15E-57 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15635 12b305e927c7c4757ef244e0da7fe1af 161 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 160 35.764 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15635 12b305e927c7c4757ef244e0da7fe1af 161 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 9.9E-65 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_03315 7cb875db4fa50d56ceade029b3f155da 281 SUPERFAMILY SSF55136 124 274 3.49E-42 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_03315 7cb875db4fa50d56ceade029b3f155da 281 SMART SM00422 7 77 2.2E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_03315 7cb875db4fa50d56ceade029b3f155da 281 Pfam PF13411 MerR HTH family regulatory protein 7 76 9.6E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_03315 7cb875db4fa50d56ceade029b3f155da 281 Gene3D G3DSA:3.20.80.10 199 276 4.4E-14 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_03315 7cb875db4fa50d56ceade029b3f155da 281 Gene3D G3DSA:1.10.1660.10 4 142 1.5E-28 T 14-10-2018 C2I25_03315 7cb875db4fa50d56ceade029b3f155da 281 Pfam PF06445 GyrI-like small molecule binding domain 162 273 9.4E-12 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain C2I25_03315 7cb875db4fa50d56ceade029b3f155da 281 SUPERFAMILY SSF46955 6 112 7.33E-25 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_03315 7cb875db4fa50d56ceade029b3f155da 281 SMART SM00871 123 274 2.2E-12 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_00240 732158ca2acddb04298473b9f4271a81 246 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 122 4.7E-35 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I25_00240 732158ca2acddb04298473b9f4271a81 246 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 78 96 4.7E-35 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I25_00240 732158ca2acddb04298473b9f4271a81 246 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 147 175 4.7E-35 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I25_00240 732158ca2acddb04298473b9f4271a81 246 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 4.7E-35 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I25_00240 732158ca2acddb04298473b9f4271a81 246 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 214 8.9E-52 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I25_00240 732158ca2acddb04298473b9f4271a81 246 ProSitePatterns PS01218 TatC family signature. 147 166 - T 14-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site C2I25_00240 732158ca2acddb04298473b9f4271a81 246 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 219 1.7E-56 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I25_00240 732158ca2acddb04298473b9f4271a81 246 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 231 15.493 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I25_09785 74c512e01ba0c770146b24b3abf18410 393 SUPERFAMILY SSF49764 321 387 2.14E-5 T 14-10-2018 IPR008978 HSP20-like chaperone C2I25_09785 74c512e01ba0c770146b24b3abf18410 393 SUPERFAMILY SSF52540 2 296 4.21E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09785 74c512e01ba0c770146b24b3abf18410 393 Gene3D G3DSA:3.40.50.300 1 315 1.8E-86 T 14-10-2018 C2I25_09785 74c512e01ba0c770146b24b3abf18410 393 Pfam PF02374 Anion-transporting ATPase 2 303 1.5E-97 T 14-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 C2I25_09785 74c512e01ba0c770146b24b3abf18410 393 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 7 302 1.5E-85 T 14-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 C2I25_09785 74c512e01ba0c770146b24b3abf18410 393 Gene3D G3DSA:2.60.40.790 318 390 4.3E-21 T 14-10-2018 IPR008978 HSP20-like chaperone C2I25_20150 c8b70843440f16db7bce025926670444 205 Hamap MF_00328 Guanylate kinase [gmk]. 4 188 37.038 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 C2I25_20150 c8b70843440f16db7bce025926670444 205 Gene3D G3DSA:3.40.50.300 10 184 4.2E-68 T 14-10-2018 C2I25_20150 c8b70843440f16db7bce025926670444 205 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 C2I25_20150 c8b70843440f16db7bce025926670444 205 Pfam PF00625 Guanylate kinase 8 184 6.2E-53 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit C2I25_20150 c8b70843440f16db7bce025926670444 205 SMART SM00072 5 188 7.2E-78 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit C2I25_20150 c8b70843440f16db7bce025926670444 205 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 184 1.2E-73 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 C2I25_20150 c8b70843440f16db7bce025926670444 205 Gene3D G3DSA:3.30.63.10 38 97 4.2E-68 T 14-10-2018 C2I25_20150 c8b70843440f16db7bce025926670444 205 SUPERFAMILY SSF52540 3 192 2.67E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24170 5c6f0857fd4f07e56038979b5d57dd81 292 Pfam PF01636 Phosphotransferase enzyme family 31 254 1.7E-33 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_24170 5c6f0857fd4f07e56038979b5d57dd81 292 Gene3D G3DSA:3.90.1200.10 98 289 1.2E-23 T 14-10-2018 C2I25_24170 5c6f0857fd4f07e56038979b5d57dd81 292 Gene3D G3DSA:3.30.200.20 7 94 4.7E-10 T 14-10-2018 C2I25_24170 5c6f0857fd4f07e56038979b5d57dd81 292 SUPERFAMILY SSF56112 12 262 4.05E-47 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_22265 03a8e2be732548fea26d2e9b5cfed17a 273 SUPERFAMILY SSF55136 127 271 2.62E-14 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_22265 03a8e2be732548fea26d2e9b5cfed17a 273 SUPERFAMILY SSF46955 2 104 1.97E-21 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_22265 03a8e2be732548fea26d2e9b5cfed17a 273 Pfam PF13411 MerR HTH family regulatory protein 2 71 2.9E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_22265 03a8e2be732548fea26d2e9b5cfed17a 273 SMART SM00422 2 72 5.2E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_22265 03a8e2be732548fea26d2e9b5cfed17a 273 Gene3D G3DSA:1.10.1660.10 1 120 5.1E-22 T 14-10-2018 C2I25_22265 03a8e2be732548fea26d2e9b5cfed17a 273 SMART SM00871 120 270 1.4E-10 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_22265 03a8e2be732548fea26d2e9b5cfed17a 273 Gene3D G3DSA:3.20.80.10 121 270 5.2E-21 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 5.1E-80 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 PIRSF PIRSF000441 1 218 1.3E-87 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 Gene3D G3DSA:2.160.10.10 67 183 2.4E-37 T 14-10-2018 C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 Gene3D G3DSA:1.10.3130.10 1 66 1.5E-25 T 14-10-2018 C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 2.8E-6 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 3.0E-8 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 SUPERFAMILY SSF51161 2 168 2.08E-57 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_11085 5172fa8e1f98a5eca27128e036edcdae 221 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 1.4E-4 T 14-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 C2I25_19185 86520390a8f53f71eb4f024b5c0bd4bf 190 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 181 35.777 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 C2I25_19185 86520390a8f53f71eb4f024b5c0bd4bf 190 Gene3D G3DSA:1.10.10.10 84 179 2.7E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19185 86520390a8f53f71eb4f024b5c0bd4bf 190 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 184 6.1E-53 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 C2I25_19185 86520390a8f53f71eb4f024b5c0bd4bf 190 PIRSF PIRSF019345 1 184 1.4E-56 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 C2I25_19185 86520390a8f53f71eb4f024b5c0bd4bf 190 SUPERFAMILY SSF46785 1 81 5.58E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19185 86520390a8f53f71eb4f024b5c0bd4bf 190 SUPERFAMILY SSF46785 86 159 7.48E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19185 86520390a8f53f71eb4f024b5c0bd4bf 190 Gene3D G3DSA:1.10.10.10 2 83 1.3E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19185 86520390a8f53f71eb4f024b5c0bd4bf 190 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 168 2.3E-57 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 C2I25_18850 8b410094e8a0325f967cc5276ee9b448 462 Gene3D G3DSA:3.90.1150.10 22 455 2.8E-170 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_18850 8b410094e8a0325f967cc5276ee9b448 462 SUPERFAMILY SSF53383 23 457 9.46E-135 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_18850 8b410094e8a0325f967cc5276ee9b448 462 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 26 455 2.4E-175 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 C2I25_18850 8b410094e8a0325f967cc5276ee9b448 462 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 263 300 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_18850 8b410094e8a0325f967cc5276ee9b448 462 Gene3D G3DSA:3.40.640.10 76 353 2.8E-170 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_18850 8b410094e8a0325f967cc5276ee9b448 462 Pfam PF00202 Aminotransferase class-III 41 455 5.5E-125 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_18850 8b410094e8a0325f967cc5276ee9b448 462 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 14 458 52.66 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 C2I25_18850 8b410094e8a0325f967cc5276ee9b448 462 PIRSF PIRSF000521 40 458 1.0E-40 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 Gene3D G3DSA:1.10.10.1600 415 491 5.8E-23 T 14-10-2018 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 Gene3D G3DSA:3.20.20.140 1 261 7.2E-86 T 14-10-2018 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 Gene3D G3DSA:1.10.150.870 753 843 9.5E-6 T 14-10-2018 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 983 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 Pfam PF14579 Helix-hairpin-helix motif 778 865 2.9E-18 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 SMART SM00481 4 71 7.0E-22 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 Pfam PF02811 PHP domain 5 164 1.1E-36 T 14-10-2018 IPR004013 PHP domain GO:0003824 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 SUPERFAMILY SSF89550 2 254 1.08E-16 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 Pfam PF01336 OB-fold nucleic acid binding domain 956 1021 1.2E-7 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I25_16275 c9553d1a6c3eca3f856d673e694e5986 1108 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 283 705 3.6E-174 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_20885 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 SMART SM00411 1 90 4.5E-47 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_20885 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 C2I25_20885 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 Gene3D G3DSA:4.10.520.10 1 90 1.4E-39 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I25_20885 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.6E-35 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_20885 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 SUPERFAMILY SSF47729 1 90 6.04E-34 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I25_20885 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.2E-21 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_20885 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.2E-21 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_20885 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.2E-21 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_15720 13fc9040860cd2b6fbff894efe852cd5 550 Pfam PF01943 Polysaccharide biosynthesis protein 6 320 1.9E-44 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I25_15720 13fc9040860cd2b6fbff894efe852cd5 550 PIRSF PIRSF038958 1 537 4.8E-122 T 14-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I25_15720 13fc9040860cd2b6fbff894efe852cd5 550 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 372 519 1.4E-29 T 14-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I25_11460 6df57938637df77cef43629c8a4eeb25 208 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 1.7E-59 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 C2I25_11460 6df57938637df77cef43629c8a4eeb25 208 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 30.573 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 C2I25_11460 6df57938637df77cef43629c8a4eeb25 208 Gene3D G3DSA:3.40.50.300 1 207 2.8E-65 T 14-10-2018 C2I25_11460 6df57938637df77cef43629c8a4eeb25 208 SUPERFAMILY SSF52540 1 206 4.33E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11460 6df57938637df77cef43629c8a4eeb25 208 Pfam PF02223 Thymidylate kinase 8 198 5.3E-50 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 C2I25_11460 6df57938637df77cef43629c8a4eeb25 208 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 14-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 Gene3D G3DSA:3.40.50.620 176 404 4.0E-85 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 Gene3D G3DSA:3.30.2130.30 1 175 6.8E-67 T 14-10-2018 C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 SMART SM00981 75 166 1.8E-19 T 14-10-2018 IPR004114 THUMP domain GO:0003723 C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 SUPERFAMILY SSF52402 176 382 1.96E-54 T 14-10-2018 C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 7 373 2.8E-129 T 14-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 404 164.049 T 14-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 176 371 2.7E-70 T 14-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 Pfam PF02926 THUMP domain 35 162 1.1E-18 T 14-10-2018 IPR004114 THUMP domain GO:0003723 C2I25_16055 034d331a5bad15fc34e7ff83d1f1dd12 404 SUPERFAMILY SSF143437 4 174 3.31E-53 T 14-10-2018 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 PRINTS PR00412 Epoxide hydrolase signature 25 43 9.1E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 PRINTS PR00412 Epoxide hydrolase signature 243 265 9.1E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 PRINTS PR00412 Epoxide hydrolase signature 104 117 9.1E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 19 267 1.3E-91 T 14-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 10 267 37.3 T 14-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 Gene3D G3DSA:3.40.50.1820 6 268 6.5E-70 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 9.8E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 9.8E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 9.8E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 SUPERFAMILY SSF53474 3 267 3.32E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_14900 ec101bed1a9c2cd82ceb8392ffefceb2 270 Pfam PF00561 alpha/beta hydrolase fold 20 254 7.2E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_25270 29d737af2102f0df7897e08c55b866b3 215 Gene3D G3DSA:3.40.50.2300 1 118 2.2E-35 T 14-10-2018 C2I25_25270 29d737af2102f0df7897e08c55b866b3 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 210 1.0E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_25270 29d737af2102f0df7897e08c55b866b3 215 SMART SM00448 1 111 7.0E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_25270 29d737af2102f0df7897e08c55b866b3 215 Gene3D G3DSA:1.10.10.10 119 215 1.6E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25270 29d737af2102f0df7897e08c55b866b3 215 Pfam PF00072 Response regulator receiver domain 3 111 1.6E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_25270 29d737af2102f0df7897e08c55b866b3 215 SMART SM00862 139 210 1.6E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_25270 29d737af2102f0df7897e08c55b866b3 215 SUPERFAMILY SSF52172 1 167 1.96E-37 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 Pfam PF00488 MutS domain V 331 512 6.1E-35 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 SMART SM00534 328 513 2.6E-76 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 786 4.8E-272 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 SUPERFAMILY SSF52540 292 514 2.4E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 SUPERFAMILY SSF48334 17 287 8.5E-31 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 785 22.119 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 SMART SM00463 708 786 9.2E-19 T 14-10-2018 IPR002625 Smr domain C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 Pfam PF01713 Smr domain 711 786 1.2E-19 T 14-10-2018 IPR002625 Smr domain C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 SUPERFAMILY SSF160443 709 780 1.26E-9 T 14-10-2018 IPR036063 Smr domain superfamily C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 PIRSF PIRSF005814 1 786 3.5E-278 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 Gene3D G3DSA:1.10.1420.10 138 259 7.2E-11 T 14-10-2018 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 SMART SM00533 9 315 6.5E-35 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 Gene3D G3DSA:3.30.1370.110 699 786 1.7E-23 T 14-10-2018 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 Gene3D G3DSA:3.40.50.300 293 599 2.7E-82 T 14-10-2018 C2I25_16555 99d607a58d5e60f3ccbe392030c83d65 786 Gene3D G3DSA:1.10.1420.10 18 281 7.2E-11 T 14-10-2018 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 SUPERFAMILY SSF55174 1 54 9.25E-12 T 14-10-2018 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 Gene3D G3DSA:3.30.70.1560 130 200 1.8E-32 T 14-10-2018 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 SUPERFAMILY SSF55120 61 222 6.37E-41 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 Gene3D G3DSA:3.10.290.10 1 53 2.0E-18 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 SMART SM00363 1 57 3.4E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 218 2.9E-48 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 Pfam PF01479 S4 domain 1 46 6.8E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 Pfam PF00849 RNA pseudouridylate synthase 62 186 3.1E-16 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 97 111 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I25_16565 4c8aefc1a272e0c2aeceadeb0c4be359 229 Gene3D G3DSA:3.30.70.580 54 129 3.0E-22 T 14-10-2018 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 Pfam PF07687 Peptidase dimerisation domain 182 274 8.9E-16 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 368 4.5E-168 T 14-10-2018 IPR010162 Peptidase M20B, peptidase T-like C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 SUPERFAMILY SSF55031 180 285 2.75E-20 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 Gene3D G3DSA:3.30.70.360 177 288 1.6E-142 T 14-10-2018 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 PIRSF PIRSF001123 261 372 3.8E-5 T 14-10-2018 IPR008007 Peptidase M42 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 PIRSF PIRSF001123 4 96 0.033 T 14-10-2018 IPR008007 Peptidase M42 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 PIRSF PIRSF001123 80 210 5.7E-5 T 14-10-2018 IPR008007 Peptidase M42 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 Pfam PF01546 Peptidase family M20/M25/M40 74 368 4.4E-24 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 SUPERFAMILY SSF53187 5 371 4.53E-65 T 14-10-2018 C2I25_18685 cb569678b71942536a0ca5ca769b261c 372 Gene3D G3DSA:3.40.630.10 14 363 1.6E-142 T 14-10-2018 C2I25_15445 b14752cba64d4725d7deca45ed91ba84 177 SUPERFAMILY SSF48317 9 174 2.22E-41 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I25_15445 b14752cba64d4725d7deca45ed91ba84 177 SMART SM00014 61 169 2.9E-16 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_15445 b14752cba64d4725d7deca45ed91ba84 177 Gene3D G3DSA:1.20.144.10 9 97 1.2E-6 T 14-10-2018 C2I25_15445 b14752cba64d4725d7deca45ed91ba84 177 Gene3D G3DSA:1.20.144.10 98 177 4.6E-19 T 14-10-2018 C2I25_15445 b14752cba64d4725d7deca45ed91ba84 177 Pfam PF01569 PAP2 superfamily 62 172 8.8E-23 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_09145 c7bd3e138b9677b075516fd9be953c92 84 Pfam PF00364 Biotin-requiring enzyme 10 73 6.5E-5 T 14-10-2018 IPR000089 Biotin/lipoyl attachment C2I25_09145 c7bd3e138b9677b075516fd9be953c92 84 SUPERFAMILY SSF51230 7 74 7.99E-7 T 14-10-2018 IPR011053 Single hybrid motif C2I25_09145 c7bd3e138b9677b075516fd9be953c92 84 Gene3D G3DSA:2.40.50.100 3 76 4.4E-8 T 14-10-2018 C2I25_20830 447828409a6e0040f3d9624533ce81a8 252 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 211 222 - T 14-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 C2I25_20830 447828409a6e0040f3d9624533ce81a8 252 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 243 3.0E-23 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase C2I25_20830 447828409a6e0040f3d9624533ce81a8 252 SUPERFAMILY SSF56219 1 251 1.31E-80 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_20830 447828409a6e0040f3d9624533ce81a8 252 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 2.5E-101 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 C2I25_20830 447828409a6e0040f3d9624533ce81a8 252 Gene3D G3DSA:3.60.10.10 1 250 1.8E-97 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_20830 447828409a6e0040f3d9624533ce81a8 252 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 250 1.1E-99 T 14-10-2018 C2I25_20830 447828409a6e0040f3d9624533ce81a8 252 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 C2I25_17500 4629a645858ef09aa939840893d32ee9 917 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 246 5.4E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_17500 4629a645858ef09aa939840893d32ee9 917 PRINTS PR00723 Subtilisin serine protease family (S8) signature 528 544 5.4E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_17500 4629a645858ef09aa939840893d32ee9 917 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 214 5.4E-21 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_17500 4629a645858ef09aa939840893d32ee9 917 Pfam PF13860 FlgD Ig-like domain 767 802 3.9E-7 T 14-10-2018 IPR025965 FlgD Ig-like domain C2I25_17500 4629a645858ef09aa939840893d32ee9 917 SUPERFAMILY SSF52025 383 450 4.19E-15 T 14-10-2018 C2I25_17500 4629a645858ef09aa939840893d32ee9 917 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 237 247 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I25_17500 4629a645858ef09aa939840893d32ee9 917 Gene3D G3DSA:3.50.30.30 357 486 1.0E-19 T 14-10-2018 C2I25_17500 4629a645858ef09aa939840893d32ee9 917 Gene3D G3DSA:2.60.40.4070 763 812 2.6E-6 T 14-10-2018 C2I25_17500 4629a645858ef09aa939840893d32ee9 917 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 529 539 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I25_17500 4629a645858ef09aa939840893d32ee9 917 Pfam PF00082 Subtilase family 195 583 3.6E-65 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I25_17500 4629a645858ef09aa939840893d32ee9 917 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 200 211 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I25_17500 4629a645858ef09aa939840893d32ee9 917 Pfam PF02225 PA domain 385 467 2.9E-11 T 14-10-2018 IPR003137 PA domain C2I25_17500 4629a645858ef09aa939840893d32ee9 917 Pfam PF05922 Peptidase inhibitor I9 64 158 5.9E-10 T 14-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 C2I25_17500 4629a645858ef09aa939840893d32ee9 917 SUPERFAMILY SSF52743 172 592 4.06E-88 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_09075 fb79793efe866164026d8031d2abf3a4 515 SUPERFAMILY SSF53448 1 182 1.9E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09075 fb79793efe866164026d8031d2abf3a4 515 Gene3D G3DSA:3.90.550.10 1 214 3.7E-30 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09075 fb79793efe866164026d8031d2abf3a4 515 Gene3D G3DSA:3.90.550.10 249 453 1.4E-15 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09075 fb79793efe866164026d8031d2abf3a4 515 SUPERFAMILY SSF53448 260 418 1.04E-16 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09075 fb79793efe866164026d8031d2abf3a4 515 Pfam PF00535 Glycosyl transferase family 2 4 112 2.4E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_09075 fb79793efe866164026d8031d2abf3a4 515 Pfam PF00535 Glycosyl transferase family 2 262 365 8.1E-12 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_25570 2e38903b042f802c77379d62d292db51 134 Pfam PF00583 Acetyltransferase (GNAT) family 29 113 8.1E-10 T 14-10-2018 IPR000182 GNAT domain C2I25_25570 2e38903b042f802c77379d62d292db51 134 SUPERFAMILY SSF55729 6 126 3.6E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25570 2e38903b042f802c77379d62d292db51 134 Gene3D G3DSA:3.40.630.30 3 133 1.8E-29 T 14-10-2018 C2I25_19770 483fa944013e77c3ff5699bb4d8ee55c 307 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 14-10-2018 IPR030470 UbiA prenyltransferase conserved site C2I25_19770 483fa944013e77c3ff5699bb4d8ee55c 307 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 22 306 17.954 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 C2I25_19770 483fa944013e77c3ff5699bb4d8ee55c 307 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 26 303 6.5E-91 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 C2I25_19770 483fa944013e77c3ff5699bb4d8ee55c 307 Gene3D G3DSA:1.10.357.140 34 187 6.9E-18 T 14-10-2018 C2I25_19770 483fa944013e77c3ff5699bb4d8ee55c 307 Pfam PF01040 UbiA prenyltransferase family 41 290 6.8E-55 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 C2I25_10355 3f6e20599a786b7da63b985404c6797d 290 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 278 7.2E-58 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_10355 3f6e20599a786b7da63b985404c6797d 290 Gene3D G3DSA:3.40.50.1000 2 274 1.9E-80 T 14-10-2018 IPR023214 HAD superfamily C2I25_10355 3f6e20599a786b7da63b985404c6797d 290 SUPERFAMILY SSF56784 2 284 5.47E-69 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_10355 3f6e20599a786b7da63b985404c6797d 290 ProSitePatterns PS01229 Hypothetical cof family signature 2. 232 254 - T 14-10-2018 C2I25_10355 3f6e20599a786b7da63b985404c6797d 290 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 14-10-2018 C2I25_10355 3f6e20599a786b7da63b985404c6797d 290 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 251 9.5E-28 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_10355 3f6e20599a786b7da63b985404c6797d 290 Gene3D G3DSA:3.30.1240.10 80 207 1.9E-80 T 14-10-2018 C2I25_10355 3f6e20599a786b7da63b985404c6797d 290 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 278 5.2E-66 T 14-10-2018 C2I25_25290 8315392b0074ac3ae3c51fc6ed79ff7c 254 SUPERFAMILY SSF53335 11 239 2.22E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_25290 8315392b0074ac3ae3c51fc6ed79ff7c 254 Gene3D G3DSA:2.20.25.570 144 209 2.2E-32 T 14-10-2018 C2I25_25290 8315392b0074ac3ae3c51fc6ed79ff7c 254 Gene3D G3DSA:3.40.50.150 38 233 2.2E-32 T 14-10-2018 C2I25_25290 8315392b0074ac3ae3c51fc6ed79ff7c 254 Pfam PF13649 Methyltransferase domain 41 136 1.5E-12 T 14-10-2018 C2I25_16660 b58455621feb809d26b80fad128cc2c9 231 Pfam PF12730 ABC-2 family transporter protein 6 183 4.1E-7 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I25_26460 0c2d149b429255b66bc92d45b6cbd54f 210 Gene3D G3DSA:2.160.10.10 1 210 1.8E-81 T 14-10-2018 C2I25_26460 0c2d149b429255b66bc92d45b6cbd54f 210 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 122 150 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I25_26460 0c2d149b429255b66bc92d45b6cbd54f 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 113 148 3.7E-11 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_26460 0c2d149b429255b66bc92d45b6cbd54f 210 SUPERFAMILY SSF51161 15 204 9.56E-48 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_26180 ed04563875d47917c90313bc3b8a8c6d 148 Pfam PF00293 NUDIX domain 7 115 5.1E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_26180 ed04563875d47917c90313bc3b8a8c6d 148 SUPERFAMILY SSF55811 4 114 9.48E-23 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_26180 ed04563875d47917c90313bc3b8a8c6d 148 PRINTS PR00502 NUDIX hydrolase family signature 29 43 2.3E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_26180 ed04563875d47917c90313bc3b8a8c6d 148 PRINTS PR00502 NUDIX hydrolase family signature 43 58 2.3E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_26180 ed04563875d47917c90313bc3b8a8c6d 148 Gene3D G3DSA:3.90.79.10 1 139 8.1E-30 T 14-10-2018 C2I25_26180 ed04563875d47917c90313bc3b8a8c6d 148 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_18720 e444937ec418fe63eadbc5ebae8063f1 307 SUPERFAMILY SSF56281 2 305 1.02E-85 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_18720 e444937ec418fe63eadbc5ebae8063f1 307 Pfam PF00753 Metallo-beta-lactamase superfamily 26 95 2.1E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_18720 e444937ec418fe63eadbc5ebae8063f1 307 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 42.159 T 14-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 C2I25_18720 e444937ec418fe63eadbc5ebae8063f1 307 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 303 4.4E-119 T 14-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 C2I25_18720 e444937ec418fe63eadbc5ebae8063f1 307 SMART SM00849 18 270 2.2E-4 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_18720 e444937ec418fe63eadbc5ebae8063f1 307 Gene3D G3DSA:3.60.15.10 1 305 6.2E-107 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_18720 e444937ec418fe63eadbc5ebae8063f1 307 Pfam PF12706 Beta-lactamase superfamily domain 203 271 5.7E-10 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_17750 e2ec490bc5cdb269e0f0ae653b2962bb 97 Pfam PF07873 YabP family 26 89 8.1E-17 T 14-10-2018 IPR022476 Sporulation protein YabP/YqfC C2I25_17750 e2ec490bc5cdb269e0f0ae653b2962bb 97 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 7 90 1.1E-36 T 14-10-2018 IPR022477 Sporulation protein YqfC C2I25_25335 e6d763285977f48a74f9f2392eccfe2d 350 Pfam PF13378 Enolase C-terminal domain-like 143 326 1.0E-47 T 14-10-2018 IPR029065 Enolase C-terminal domain-like C2I25_25335 e6d763285977f48a74f9f2392eccfe2d 350 Gene3D G3DSA:3.30.390.10 6 115 1.7E-108 T 14-10-2018 IPR029017 Enolase-like, N-terminal C2I25_25335 e6d763285977f48a74f9f2392eccfe2d 350 SMART SM00922 140 238 1.0E-25 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal C2I25_25335 e6d763285977f48a74f9f2392eccfe2d 350 SUPERFAMILY SSF54826 1 125 1.12E-28 T 14-10-2018 C2I25_25335 e6d763285977f48a74f9f2392eccfe2d 350 SUPERFAMILY SSF51604 127 339 1.24E-63 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I25_25335 e6d763285977f48a74f9f2392eccfe2d 350 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 4 124 5.4E-18 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain C2I25_25335 e6d763285977f48a74f9f2392eccfe2d 350 Gene3D G3DSA:3.20.20.120 116 330 1.7E-108 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 SUPERFAMILY SSF46785 12 96 3.91E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 Pfam PF07729 FCD domain 88 207 1.9E-21 T 14-10-2018 IPR011711 GntR, C-terminal C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 Gene3D G3DSA:1.10.10.10 3 79 1.3E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 Gene3D G3DSA:1.20.120.530 83 216 7.1E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 76 2.1E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 SMART SM00895 87 211 7.7E-9 T 14-10-2018 IPR011711 GntR, C-terminal C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 SUPERFAMILY SSF48008 88 216 4.45E-17 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I25_02820 dfd50892b62fc0a70a72586f61de822b 223 SMART SM00345 19 77 2.3E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 SUPERFAMILY SSF52418 69 329 7.06E-94 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 SUPERFAMILY SSF47648 1 69 9.68E-23 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 3.2E-20 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 SMART SM00941 345 418 3.9E-32 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 PIRSF PIRSF000478 1 432 2.6E-171 T 14-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 14-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 418 2.6E-183 T 14-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 7.5E-27 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 SUPERFAMILY SSF54680 331 432 3.01E-30 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 Gene3D G3DSA:1.20.970.10 1 67 4.5E-29 T 14-10-2018 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 Gene3D G3DSA:3.90.1170.30 331 420 3.2E-155 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 Gene3D G3DSA:3.40.1030.10 77 330 3.2E-155 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_19025 b873c26b7a0d1870a16ffd37b1bf202d 434 Pfam PF00591 Glycosyl transferase family, a/b domain 77 306 6.6E-50 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_16320 e0d67d68c94b0799358ade0ad6cd7c47 153 Pfam PF04284 Protein of unknown function (DUF441) 7 146 2.1E-48 T 14-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame C2I25_16320 e0d67d68c94b0799358ade0ad6cd7c47 153 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 21 131 6.0E-44 T 14-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame C2I25_16320 e0d67d68c94b0799358ade0ad6cd7c47 153 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 19.171 T 14-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 Gene3D G3DSA:3.40.50.300 133 319 1.1E-65 T 14-10-2018 C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 SUPERFAMILY SSF52540 148 388 1.14E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 SUPERFAMILY SSF46689 401 447 6.27E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 172 185 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 124 1.1E-9 T 14-10-2018 IPR000014 PAS domain C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 SUPERFAMILY SSF55785 11 111 5.23E-14 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 Gene3D G3DSA:1.10.10.60 397 448 2.7E-5 T 14-10-2018 C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 Gene3D G3DSA:1.10.8.60 320 396 1.3E-19 T 14-10-2018 C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 Gene3D G3DSA:3.30.450.20 3 124 6.8E-17 T 14-10-2018 C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 Pfam PF00158 Sigma-54 interaction domain 149 315 1.3E-66 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 235 250 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 SMART SM00382 168 312 3.2E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_09740 8f528d6ab799c765937ee1789a8b87bd 455 Pfam PF13426 PAS domain 23 117 2.2E-10 T 14-10-2018 IPR000014 PAS domain C2I25_20190 9716f3668eb615a2d6fe1030558f199f 250 SUPERFAMILY SSF81606 2 241 5.49E-65 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_20190 9716f3668eb615a2d6fe1030558f199f 250 SMART SM00331 7 242 7.7E-45 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_20190 9716f3668eb615a2d6fe1030558f199f 250 SMART SM00332 1 240 2.3E-23 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_20190 9716f3668eb615a2d6fe1030558f199f 250 Gene3D G3DSA:3.60.40.10 1 244 4.8E-71 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_20190 9716f3668eb615a2d6fe1030558f199f 250 Pfam PF13672 Protein phosphatase 2C 12 203 1.3E-22 T 14-10-2018 C2I25_16830 8c75a36f96353d5625b38dd7da690d33 220 Gene3D G3DSA:3.40.50.880 1 219 3.2E-68 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_16830 8c75a36f96353d5625b38dd7da690d33 220 SUPERFAMILY SSF52317 1 216 1.12E-62 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_16830 8c75a36f96353d5625b38dd7da690d33 220 Pfam PF01965 DJ-1/PfpI family 26 213 1.4E-14 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I25_00360 661e7e7eb8397bb4f66af8232f5a1c5b 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 184 2.4E-31 T 14-10-2018 C2I25_00360 661e7e7eb8397bb4f66af8232f5a1c5b 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 86 176 3.7E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_00360 661e7e7eb8397bb4f66af8232f5a1c5b 220 Gene3D G3DSA:3.40.50.1000 5 204 1.3E-65 T 14-10-2018 IPR023214 HAD superfamily C2I25_00360 661e7e7eb8397bb4f66af8232f5a1c5b 220 SUPERFAMILY SSF56784 1 212 2.07E-55 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_00360 661e7e7eb8397bb4f66af8232f5a1c5b 220 Gene3D G3DSA:1.10.150.240 16 82 1.3E-65 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_08920 1b1c4d8146ad42c8c4b8d39cb1bec6dc 151 SUPERFAMILY SSF52833 1 151 2.95E-55 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_08920 1b1c4d8146ad42c8c4b8d39cb1bec6dc 151 Pfam PF00578 AhpC/TSA family 4 131 1.3E-40 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I25_08920 1b1c4d8146ad42c8c4b8d39cb1bec6dc 151 Gene3D G3DSA:3.40.30.10 2 151 9.1E-54 T 14-10-2018 C2I25_08920 1b1c4d8146ad42c8c4b8d39cb1bec6dc 151 PIRSF PIRSF000239 1 150 1.5E-28 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I25_17045 4d9d18b8fa62361f0620639431d2ef57 286 Pfam PF02163 Peptidase family M50 113 167 1.1E-7 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 216 257 7.9E-17 T 14-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 PIRSF PIRSF006816 1 259 8.2E-70 T 14-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 Gene3D G3DSA:2.10.240.10 216 259 1.3E-17 T 14-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 Gene3D G3DSA:2.40.30.10 1 98 5.4E-30 T 14-10-2018 C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 53 67 5.3E-8 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 112 131 5.3E-8 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 189 197 5.3E-8 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 Gene3D G3DSA:3.40.50.80 103 215 4.2E-24 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 SUPERFAMILY SSF52343 95 258 8.91E-31 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 4 259 38.4 T 14-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 Pfam PF00970 Oxidoreductase FAD-binding domain 8 98 1.5E-4 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 SUPERFAMILY SSF63380 1 100 6.09E-22 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I25_20070 0a09135143c3d5dd8cc2ff95f77cab70 259 Pfam PF00175 Oxidoreductase NAD-binding domain 113 202 2.7E-4 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 C2I25_03555 efbc8e1757a8242a9e8dd072e69dfcb9 197 Gene3D G3DSA:3.40.50.2020 3 188 2.7E-54 T 14-10-2018 C2I25_03555 efbc8e1757a8242a9e8dd072e69dfcb9 197 Pfam PF00156 Phosphoribosyl transferase domain 34 156 2.9E-9 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_03555 efbc8e1757a8242a9e8dd072e69dfcb9 197 SUPERFAMILY SSF53271 1 189 3.65E-47 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_03555 efbc8e1757a8242a9e8dd072e69dfcb9 197 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 190 1.8E-85 T 14-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 C2I25_03555 efbc8e1757a8242a9e8dd072e69dfcb9 197 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 42.88 T 14-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 Pfam PF12833 Helix-turn-helix domain 28 105 2.1E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 4.0E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 4.0E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 SMART SM00342 21 104 7.0E-28 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 SUPERFAMILY SSF55136 128 290 2.88E-32 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 Gene3D G3DSA:1.10.10.60 2 57 7.0E-14 T 14-10-2018 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 Pfam PF06445 GyrI-like small molecule binding domain 128 287 5.7E-31 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 SMART SM00871 128 288 1.9E-37 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 Gene3D G3DSA:3.20.80.10 128 290 3.7E-41 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 SUPERFAMILY SSF46689 57 114 5.38E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 Gene3D G3DSA:1.10.10.60 58 116 1.7E-15 T 14-10-2018 C2I25_15040 a488a39f7fc2897ec8c36a9385986a59 290 SUPERFAMILY SSF46689 6 55 1.08E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_09650 fa2741b57bb3e54c1e3efb8cc0a7203f 371 SUPERFAMILY SSF53187 5 369 8.29E-63 T 14-10-2018 C2I25_09650 fa2741b57bb3e54c1e3efb8cc0a7203f 371 Pfam PF07687 Peptidase dimerisation domain 173 263 1.2E-8 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_09650 fa2741b57bb3e54c1e3efb8cc0a7203f 371 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 10 352 2.8E-84 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_09650 fa2741b57bb3e54c1e3efb8cc0a7203f 371 Gene3D G3DSA:3.40.630.10 11 352 8.1E-77 T 14-10-2018 C2I25_09650 fa2741b57bb3e54c1e3efb8cc0a7203f 371 Pfam PF01546 Peptidase family M20/M25/M40 66 364 7.6E-21 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_09650 fa2741b57bb3e54c1e3efb8cc0a7203f 371 Gene3D G3DSA:3.30.70.360 166 277 8.1E-77 T 14-10-2018 C2I25_09650 fa2741b57bb3e54c1e3efb8cc0a7203f 371 SUPERFAMILY SSF55031 171 276 6.58E-19 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_09650 fa2741b57bb3e54c1e3efb8cc0a7203f 371 PIRSF PIRSF005962 1 371 1.5E-89 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_13260 b0b3e8561aa2ff2da7cf8fd7e6d9540c 104 Pfam PF01638 HxlR-like helix-turn-helix 17 103 1.5E-31 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_13260 b0b3e8561aa2ff2da7cf8fd7e6d9540c 104 Gene3D G3DSA:1.10.10.10 6 104 1.9E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_13260 b0b3e8561aa2ff2da7cf8fd7e6d9540c 104 SUPERFAMILY SSF46785 3 103 6.12E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_28235 3ab55c35f58aa9cd4d875d4477456e19 486 SUPERFAMILY SSF53720 4 485 4.58E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_28235 3ab55c35f58aa9cd4d875d4477456e19 486 Gene3D G3DSA:3.40.605.10 27 462 4.0E-151 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_28235 3ab55c35f58aa9cd4d875d4477456e19 486 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 9 485 2.3E-180 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 C2I25_28235 3ab55c35f58aa9cd4d875d4477456e19 486 Hamap MF_01670 Malonate-semialdehyde dehydrogenase [iolA]. 3 485 73.988 T 14-10-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642 C2I25_28235 3ab55c35f58aa9cd4d875d4477456e19 486 Gene3D G3DSA:3.40.309.10 254 454 4.0E-151 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_28235 3ab55c35f58aa9cd4d875d4477456e19 486 Pfam PF00171 Aldehyde dehydrogenase family 17 481 8.2E-150 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_28235 3ab55c35f58aa9cd4d875d4477456e19 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I25_16860 be4444789914abbb38b2a2c9e0b4fef8 245 SUPERFAMILY SSF54211 1 140 1.52E-43 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_16860 be4444789914abbb38b2a2c9e0b4fef8 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 6.0E-117 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 C2I25_16860 be4444789914abbb38b2a2c9e0b4fef8 245 SUPERFAMILY SSF55666 151 238 3.14E-25 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_16860 be4444789914abbb38b2a2c9e0b4fef8 245 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site C2I25_16860 be4444789914abbb38b2a2c9e0b4fef8 245 Gene3D G3DSA:3.30.230.70 13 245 7.3E-66 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_16860 be4444789914abbb38b2a2c9e0b4fef8 245 Pfam PF03725 3' exoribonuclease family, domain 2 159 225 1.4E-11 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_16860 be4444789914abbb38b2a2c9e0b4fef8 245 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 4.2E-23 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I25_16860 be4444789914abbb38b2a2c9e0b4fef8 245 Hamap MF_00564 Ribonuclease PH [rph]. 11 238 43.935 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 C2I25_04130 9a452e0991a0c74ce61b8bc1b2ef8f56 680 Pfam PF00912 Transglycosylase 69 240 4.0E-61 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_04130 9a452e0991a0c74ce61b8bc1b2ef8f56 680 Gene3D G3DSA:3.40.710.10 268 618 3.3E-122 T 14-10-2018 C2I25_04130 9a452e0991a0c74ce61b8bc1b2ef8f56 680 SUPERFAMILY SSF53955 55 262 1.04E-72 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily C2I25_04130 9a452e0991a0c74ce61b8bc1b2ef8f56 680 Pfam PF00905 Penicillin binding protein transpeptidase domain 336 613 8.7E-38 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_04130 9a452e0991a0c74ce61b8bc1b2ef8f56 680 SUPERFAMILY SSF56601 222 627 6.61E-111 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_04130 9a452e0991a0c74ce61b8bc1b2ef8f56 680 Gene3D G3DSA:1.10.3810.10 59 256 2.0E-74 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_04130 9a452e0991a0c74ce61b8bc1b2ef8f56 680 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 78 617 1.6E-184 T 14-10-2018 C2I25_24400 b103454fd23a81aa3290c682d943f995 155 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_24400 b103454fd23a81aa3290c682d943f995 155 Pfam PF00293 NUDIX domain 16 127 4.8E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_24400 b103454fd23a81aa3290c682d943f995 155 Gene3D G3DSA:3.90.79.10 1 155 3.2E-36 T 14-10-2018 C2I25_24400 b103454fd23a81aa3290c682d943f995 155 SUPERFAMILY SSF55811 13 150 7.58E-22 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 SMART SM00155 121 148 0.042 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 SMART SM00155 290 317 1.4E-4 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 SUPERFAMILY SSF56024 203 362 5.61E-38 T 14-10-2018 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 SUPERFAMILY SSF56024 24 196 1.07E-40 T 14-10-2018 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 Gene3D G3DSA:3.30.870.10 203 353 5.6E-27 T 14-10-2018 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 Pfam PF13091 PLD-like domain 39 181 1.5E-12 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 Pfam PF13091 PLD-like domain 220 339 9.6E-29 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 PIRSF PIRSF000850 206 268 5.9E-5 T 14-10-2018 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 PIRSF PIRSF000850 280 347 13.0 T 14-10-2018 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 PIRSF PIRSF000850 14 109 0.2 T 14-10-2018 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 Gene3D G3DSA:3.30.870.10 22 202 1.4E-40 T 14-10-2018 C2I25_01400 36ce3907c890e60cddd6b9fddb111c15 377 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 21 374 5.4E-95 T 14-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 81 93 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 Gene3D G3DSA:2.10.109.10 59 182 5.8E-44 T 14-10-2018 C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 177 1.2E-51 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 SUPERFAMILY SSF51306 27 182 1.09E-51 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 Pfam PF00717 Peptidase S24-like 36 103 2.0E-18 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 4.9E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 4.9E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 91 4.9E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_24210 d2ae478bed8f88dfb41632e2d5691ec4 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I25_13245 e4b4865d266c16de6cdb19b6cfbcc2f4 211 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 1.5E-18 T 14-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal C2I25_13245 e4b4865d266c16de6cdb19b6cfbcc2f4 211 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 201 1.7E-79 T 14-10-2018 IPR015796 Impact family, bacterial/archaeal C2I25_13245 e4b4865d266c16de6cdb19b6cfbcc2f4 211 Gene3D G3DSA:3.30.230.30 2 133 9.7E-52 T 14-10-2018 IPR036956 Impact, N-terminal domain superfamily C2I25_13245 e4b4865d266c16de6cdb19b6cfbcc2f4 211 SUPERFAMILY SSF54211 3 130 6.45E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_13245 e4b4865d266c16de6cdb19b6cfbcc2f4 211 Pfam PF01205 Uncharacterized protein family UPF0029 19 122 1.6E-33 T 14-10-2018 IPR001498 Impact, N-terminal C2I25_13245 e4b4865d266c16de6cdb19b6cfbcc2f4 211 SUPERFAMILY SSF54980 135 200 5.04E-11 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_13245 e4b4865d266c16de6cdb19b6cfbcc2f4 211 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 14-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF10385 RNA polymerase beta subunit external 1 domain 546 613 2.4E-23 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1100.10 389 585 5.8E-75 T 14-10-2018 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1146 12.593 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:2.40.270.10 751 789 3.3E-6 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1800.10 1056 1108 1.1E-10 T 14-10-2018 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 895 0.0 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 6.5E-27 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 373 409 4.7E-6 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1100.10 20 153 3.7E-56 T 14-10-2018 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1110.10 154 264 4.6E-7 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04565 RNA polymerase Rpb2, domain 3 468 536 1.3E-30 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04560 RNA polymerase Rpb2, domain 7 1070 1145 1.3E-27 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 SUPERFAMILY SSF64484 13 1156 0.0 T 14-10-2018 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1100.10 601 670 1.3E-19 T 14-10-2018 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:2.40.50.150 790 929 2.8E-60 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF00562 RNA polymerase Rpb2, domain 6 675 1068 2.7E-162 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:2.40.50.100 671 750 4.8E-26 T 14-10-2018 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:2.40.270.10 981 1046 1.6E-24 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04563 RNA polymerase beta subunit 28 453 5.6E-31 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11015 bb95a0509f76cfa76bff0f777fcde802 1177 ProSitePatterns PS01166 RNA polymerases beta chain signature. 921 933 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_11375 7aee6e6677421f0c25cfd7f0d2d4fac4 124 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 14-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 C2I25_11375 7aee6e6677421f0c25cfd7f0d2d4fac4 124 SUPERFAMILY SSF55298 2 123 8.95E-48 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 C2I25_11375 7aee6e6677421f0c25cfd7f0d2d4fac4 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 122 1.1E-55 T 14-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 C2I25_11375 7aee6e6677421f0c25cfd7f0d2d4fac4 124 Gene3D G3DSA:3.30.1330.40 1 124 2.0E-54 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 C2I25_11375 7aee6e6677421f0c25cfd7f0d2d4fac4 124 Pfam PF01042 Endoribonuclease L-PSP 7 122 1.6E-47 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 C2I25_07520 0a10eba4fd2f16ab4f40ae3b89b09e48 369 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 354 7.6E-47 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_07520 0a10eba4fd2f16ab4f40ae3b89b09e48 369 Pfam PF03845 Spore germination protein 9 323 4.4E-81 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_12160 08ae2246a662eb20632f9ba6a054293f 325 SMART SM00354 1 71 3.2E-28 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_12160 08ae2246a662eb20632f9ba6a054293f 325 Gene3D G3DSA:3.40.50.2300 62 304 3.2E-58 T 14-10-2018 C2I25_12160 08ae2246a662eb20632f9ba6a054293f 325 Gene3D G3DSA:3.40.50.2300 158 285 3.2E-58 T 14-10-2018 C2I25_12160 08ae2246a662eb20632f9ba6a054293f 325 SUPERFAMILY SSF47413 1 60 3.02E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_12160 08ae2246a662eb20632f9ba6a054293f 325 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 310 1.4E-26 T 14-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain C2I25_12160 08ae2246a662eb20632f9ba6a054293f 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.2E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_12160 08ae2246a662eb20632f9ba6a054293f 325 Gene3D G3DSA:1.10.260.40 2 59 2.4E-19 T 14-10-2018 C2I25_12160 08ae2246a662eb20632f9ba6a054293f 325 SUPERFAMILY SSF53822 61 325 1.35E-54 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_05335 e6bc084de096d03c6911851978fe132e 228 Pfam PF13712 Glycosyltransferase like family 10 220 2.2E-80 T 14-10-2018 C2I25_05335 e6bc084de096d03c6911851978fe132e 228 Gene3D G3DSA:3.90.550.10 8 227 1.6E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_20385 58870723be3cda9ec506486c182d3d0f 240 Gene3D G3DSA:3.40.1160.10 2 239 4.1E-82 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_20385 58870723be3cda9ec506486c182d3d0f 240 Pfam PF00696 Amino acid kinase family 7 217 4.4E-29 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I25_20385 58870723be3cda9ec506486c182d3d0f 240 SUPERFAMILY SSF53633 4 238 3.14E-74 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_20385 58870723be3cda9ec506486c182d3d0f 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 4.1E-102 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 C2I25_20385 58870723be3cda9ec506486c182d3d0f 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 44.816 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 C2I25_20385 58870723be3cda9ec506486c182d3d0f 240 PIRSF PIRSF005650 1 240 4.4E-98 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 Pfam PF00551 Formyl transferase 3 180 2.4E-39 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 SUPERFAMILY SSF50486 205 310 4.55E-31 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 309 2.4E-112 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 Gene3D G3DSA:3.10.25.10 207 314 9.4E-42 T 14-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 2.3E-27 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 SUPERFAMILY SSF53328 2 206 9.03E-68 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 Gene3D G3DSA:3.40.50.170 1 206 1.6E-89 T 14-10-2018 C2I25_20175 51dec5b51840394b6eb315310fb88036 314 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 35.654 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 C2I25_22190 53609c43dfbe2fa76632848571418b4e 364 SUPERFAMILY SSF48452 242 362 4.93E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_22190 53609c43dfbe2fa76632848571418b4e 364 Gene3D G3DSA:1.25.40.10 4 364 3.1E-89 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_22190 53609c43dfbe2fa76632848571418b4e 364 SMART SM00028 131 164 420.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_22190 53609c43dfbe2fa76632848571418b4e 364 SMART SM00028 246 279 0.63 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_22190 53609c43dfbe2fa76632848571418b4e 364 SMART SM00028 212 245 31.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_22190 53609c43dfbe2fa76632848571418b4e 364 SUPERFAMILY SSF48452 125 266 4.03E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_21855 5bcff19716cefc601167fad047e5b14e 185 SUPERFAMILY SSF51161 28 175 3.88E-44 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_21855 5bcff19716cefc601167fad047e5b14e 185 Gene3D G3DSA:2.160.10.10 2 184 8.9E-60 T 14-10-2018 C2I25_21855 5bcff19716cefc601167fad047e5b14e 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 94 122 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I25_21855 5bcff19716cefc601167fad047e5b14e 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 86 120 1.2E-7 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_21670 dfa1c15bfd002191d4461c36a608a522 698 SUPERFAMILY SSF53300 33 178 2.47E-8 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I25_21670 dfa1c15bfd002191d4461c36a608a522 698 Gene3D G3DSA:3.40.50.410 31 201 6.0E-9 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 302 2.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 274 288 2.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 326 2.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 2.7E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 234 345 1.6E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 Gene3D G3DSA:3.30.565.10 185 344 2.9E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 SMART SM00387 233 348 2.0E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 SUPERFAMILY SSF55874 179 344 2.51E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_17085 004a7f47256f4eb8f6f44ec0a379addc 360 Gene3D G3DSA:1.10.287.130 131 184 2.9E-36 T 14-10-2018 C2I25_20025 ab981058959d4a613e653f0e439b4535 109 PIRSF PIRSF026544 1 109 2.4E-49 T 14-10-2018 IPR016841 Transcription regulator DksA-related, predicted C2I25_20025 ab981058959d4a613e653f0e439b4535 109 Gene3D G3DSA:1.20.120.910 2 103 2.5E-12 T 14-10-2018 C2I25_13705 ba00b6d79a3bb751a5d80e6a5e450523 500 Pfam PF13295 Domain of unknown function (DUF4077) 2 173 1.9E-91 T 14-10-2018 IPR025278 Domain of unknown function DUF4077 C2I25_13705 ba00b6d79a3bb751a5d80e6a5e450523 500 Gene3D G3DSA:1.10.287.950 175 500 1.7E-49 T 14-10-2018 C2I25_13705 ba00b6d79a3bb751a5d80e6a5e450523 500 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 298 455 3.1E-30 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_13705 ba00b6d79a3bb751a5d80e6a5e450523 500 SMART SM00283 227 500 1.9E-33 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_13705 ba00b6d79a3bb751a5d80e6a5e450523 500 SUPERFAMILY SSF58104 205 496 6.8E-53 T 14-10-2018 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 152 8.6E-44 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 234 246 - T 14-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 Gene3D G3DSA:1.10.1040.10 166 296 1.0E-49 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 Gene3D G3DSA:3.40.50.720 1 165 9.0E-52 T 14-10-2018 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 166 275 2.5E-24 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 SUPERFAMILY SSF48179 164 296 2.79E-40 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 SUPERFAMILY SSF51735 1 152 5.87E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 SMART SM01350 166 297 2.9E-6 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 22 9.9E-27 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 155 183 9.9E-27 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 58 87 9.9E-27 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 230 257 9.9E-27 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_22920 dc0bb04f63dc65b0db0a27a8b05594c7 297 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 297 9.7E-149 T 14-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 C2I25_07515 7d3328ace5c9d4ce78be4c385619dbc0 361 Gene3D G3DSA:3.30.300.210 217 360 1.9E-12 T 14-10-2018 IPR038501 Spore germination GerAC superfamily C2I25_07515 7d3328ace5c9d4ce78be4c385619dbc0 361 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 3 360 4.9E-92 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_07515 7d3328ace5c9d4ce78be4c385619dbc0 361 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 195 358 6.0E-23 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_28205 91ac0cf595accc408989fc96c248b13f 1029 Pfam PF13476 AAA domain 6 208 1.1E-30 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain C2I25_28205 91ac0cf595accc408989fc96c248b13f 1029 Pfam PF13558 Putative exonuclease SbcCD, C subunit 924 985 2.0E-13 T 14-10-2018 C2I25_28205 91ac0cf595accc408989fc96c248b13f 1029 Gene3D G3DSA:3.40.50.300 780 1026 3.9E-25 T 14-10-2018 C2I25_28205 91ac0cf595accc408989fc96c248b13f 1029 Gene3D G3DSA:3.40.50.300 1 324 2.9E-40 T 14-10-2018 C2I25_28205 91ac0cf595accc408989fc96c248b13f 1029 SUPERFAMILY SSF52540 26 1012 2.77E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 Gene3D G3DSA:3.10.50.10 338 421 1.4E-159 T 14-10-2018 IPR029070 Chitinase insertion domain superfamily C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 SMART SM00636 39 450 1.3E-161 T 14-10-2018 IPR011583 Chitinase II GO:0008061 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 Gene3D G3DSA:2.60.40.290 578 672 3.3E-22 T 14-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 SUPERFAMILY SSF54556 339 421 1.31E-22 T 14-10-2018 IPR029070 Chitinase insertion domain superfamily C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 Gene3D G3DSA:2.60.40.10 483 567 5.9E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 Pfam PF00041 Fibronectin type III domain 488 559 1.1E-9 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 SUPERFAMILY SSF49265 481 561 1.41E-15 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 Pfam PF00553 Cellulose binding domain 580 662 8.2E-20 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 SUPERFAMILY SSF49384 574 670 1.81E-24 T 14-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 SMART SM00060 485 557 2.4E-13 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 ProSitePatterns PS01095 Chitinases family 18 active site. 201 209 - T 14-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 SUPERFAMILY SSF51445 34 451 1.26E-101 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 Gene3D G3DSA:3.20.20.80 41 450 1.4E-159 T 14-10-2018 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 Pfam PF00704 Glycosyl hydrolases family 18 40 450 1.4E-99 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 C2I25_09380 7c73be0a495740a3714951d95b32c46a 674 SMART SM00637 579 672 1.0E-32 T 14-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 C2I25_10610 5c5d44337a42315d4ad9433d6fe4e078 471 Pfam PF01565 FAD binding domain 42 173 2.1E-27 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I25_10610 5c5d44337a42315d4ad9433d6fe4e078 471 Gene3D G3DSA:3.30.465.10 90 204 2.3E-27 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_10610 5c5d44337a42315d4ad9433d6fe4e078 471 Pfam PF04030 D-arabinono-1,4-lactone oxidase 197 467 1.9E-6 T 14-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 C2I25_10610 5c5d44337a42315d4ad9433d6fe4e078 471 SUPERFAMILY SSF56176 24 202 2.76E-38 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_10610 5c5d44337a42315d4ad9433d6fe4e078 471 SUPERFAMILY SSF55103 180 456 2.91E-20 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 C2I25_09850 5c5f9e381fefa8b8c3030aa52e6c5406 753 Gene3D G3DSA:1.10.486.10 391 554 2.5E-130 T 14-10-2018 C2I25_09850 5c5f9e381fefa8b8c3030aa52e6c5406 753 Gene3D G3DSA:1.10.10.160 119 195 3.0E-110 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily C2I25_09850 5c5f9e381fefa8b8c3030aa52e6c5406 753 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 11 750 0.0 T 14-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 C2I25_09850 5c5f9e381fefa8b8c3030aa52e6c5406 753 Pfam PF13361 UvrD-like helicase C-terminal domain 285 623 3.6E-75 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 C2I25_09850 5c5f9e381fefa8b8c3030aa52e6c5406 753 Gene3D G3DSA:3.40.50.300 288 641 2.5E-130 T 14-10-2018 C2I25_09850 5c5f9e381fefa8b8c3030aa52e6c5406 753 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 279 1.7E-87 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 C2I25_09850 5c5f9e381fefa8b8c3030aa52e6c5406 753 SUPERFAMILY SSF52540 9 650 3.26E-188 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09850 5c5f9e381fefa8b8c3030aa52e6c5406 753 Gene3D G3DSA:3.40.50.300 15 282 3.0E-110 T 14-10-2018 C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 130 1.2E-14 T 14-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 23.023 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 SUPERFAMILY SSF51344 2 83 3.01E-24 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 85 2.0E-38 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 7.5E-30 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 129 9.9E-38 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 SUPERFAMILY SSF46604 87 131 5.75E-10 T 14-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 Gene3D G3DSA:1.20.5.440 89 133 4.2E-16 T 14-10-2018 C2I25_12660 0f28386e791370a749c3bfe6449aa904 133 Gene3D G3DSA:2.60.15.10 1 88 1.2E-32 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_25390 eebe7d1178f6839be1c874c6fdfc4ab9 110 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 95 6.5E-27 T 14-10-2018 C2I25_25390 eebe7d1178f6839be1c874c6fdfc4ab9 110 Gene3D G3DSA:3.10.20.440 6 103 7.5E-23 T 14-10-2018 C2I25_25390 eebe7d1178f6839be1c874c6fdfc4ab9 110 SUPERFAMILY SSF54292 19 109 3.05E-22 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I25_15900 f8798f1fa78fb51d5559be01143ab29e 124 Pfam PF14119 Domain of unknown function (DUF4288) 6 101 5.8E-29 T 14-10-2018 IPR025630 Protein of unknown function DUF4288 C2I25_18985 279d9ff9b555cbb6e027d399d14e78ba 183 Pfam PF13302 Acetyltransferase (GNAT) domain 16 156 9.2E-17 T 14-10-2018 IPR000182 GNAT domain C2I25_18985 279d9ff9b555cbb6e027d399d14e78ba 183 Gene3D G3DSA:3.40.630.30 6 182 1.0E-36 T 14-10-2018 C2I25_18985 279d9ff9b555cbb6e027d399d14e78ba 183 SUPERFAMILY SSF55729 9 182 2.61E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 Gene3D G3DSA:3.40.50.2020 13 305 1.3E-127 T 14-10-2018 C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 SMART SM01400 10 126 1.4E-82 T 14-10-2018 C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 10 317 51.753 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 5.6E-132 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 SUPERFAMILY SSF53271 75 309 4.88E-68 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 4.6E-25 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 Gene3D G3DSA:3.40.50.2020 153 293 1.3E-127 T 14-10-2018 C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 1.5E-52 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 C2I25_11360 6387e58d06a3a50db1ea517e5c8a24b1 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 C2I25_25345 045437e5dd73d2e0bf123962b084ef1e 540 Gene3D G3DSA:3.10.105.10 289 511 1.6E-174 T 14-10-2018 C2I25_25345 045437e5dd73d2e0bf123962b084ef1e 540 PIRSF PIRSF002741 1 540 8.3E-98 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_25345 045437e5dd73d2e0bf123962b084ef1e 540 SUPERFAMILY SSF53850 35 530 1.38E-122 T 14-10-2018 C2I25_25345 045437e5dd73d2e0bf123962b084ef1e 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 459 6.6E-77 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_25345 045437e5dd73d2e0bf123962b084ef1e 540 Gene3D G3DSA:3.90.76.10 68 189 1.6E-174 T 14-10-2018 C2I25_25345 045437e5dd73d2e0bf123962b084ef1e 540 Gene3D G3DSA:3.40.190.10 49 528 1.6E-174 T 14-10-2018 C2I25_07335 4450355c2777a100abbd5353e85e4b9f 367 Gene3D G3DSA:2.40.30.170 211 281 2.2E-18 T 14-10-2018 C2I25_07335 4450355c2777a100abbd5353e85e4b9f 367 Gene3D G3DSA:2.40.420.20 282 366 2.9E-13 T 14-10-2018 C2I25_07335 4450355c2777a100abbd5353e85e4b9f 367 Gene3D G3DSA:2.40.50.100 74 210 2.2E-18 T 14-10-2018 C2I25_07335 4450355c2777a100abbd5353e85e4b9f 367 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 366 5.0E-33 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 C2I25_07335 4450355c2777a100abbd5353e85e4b9f 367 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 75 254 5.9E-8 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain C2I25_07335 4450355c2777a100abbd5353e85e4b9f 367 Gene3D G3DSA:1.10.287.470 95 168 2.2E-18 T 14-10-2018 C2I25_25870 64286be934b4dbb42704ec6306258157 389 SUPERFAMILY SSF53067 213 367 4.53E-12 T 14-10-2018 C2I25_25870 64286be934b4dbb42704ec6306258157 389 SUPERFAMILY SSF53067 6 189 6.48E-7 T 14-10-2018 C2I25_25870 64286be934b4dbb42704ec6306258157 389 Gene3D G3DSA:3.30.420.40 6 212 9.6E-13 T 14-10-2018 C2I25_25870 64286be934b4dbb42704ec6306258157 389 Gene3D G3DSA:3.30.420.40 213 344 4.9E-11 T 14-10-2018 C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 Gene3D G3DSA:2.60.40.10 23 162 2.9E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 SUPERFAMILY SSF49478 172 236 2.79E-7 T 14-10-2018 C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 Gene3D G3DSA:2.60.40.10 410 515 9.0E-25 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 Gene3D G3DSA:2.60.40.740 269 409 7.0E-38 T 14-10-2018 C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 267 389 2.4E-23 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 Pfam PF00746 LPXTG cell wall anchor motif 518 549 6.3E-6 T 14-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 Gene3D G3DSA:2.60.40.10 163 268 1.4E-40 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 519 549 1.0E-6 T 14-10-2018 C2I25_27005 716725b22e33b1b7a5c27917d93026c1 553 SUPERFAMILY SSF49478 419 479 1.33E-5 T 14-10-2018 C2I25_19990 7068e89336ec706f0b769ca2f2c51e57 272 Gene3D G3DSA:3.60.140.10 6 271 3.4E-89 T 14-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily C2I25_19990 7068e89336ec706f0b769ca2f2c51e57 272 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 28 264 1.1E-70 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase C2I25_19990 7068e89336ec706f0b769ca2f2c51e57 272 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 35 266 1.3E-55 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase C2I25_19990 7068e89336ec706f0b769ca2f2c51e57 272 SUPERFAMILY SSF64438 10 268 9.89E-79 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic C2I25_19435 75997fb6adff71af3fa08a57d98e5db7 387 Gene3D G3DSA:3.90.1150.10 29 377 2.6E-127 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_19435 75997fb6adff71af3fa08a57d98e5db7 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 C2I25_19435 75997fb6adff71af3fa08a57d98e5db7 387 Gene3D G3DSA:3.40.640.10 58 280 2.6E-127 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_19435 75997fb6adff71af3fa08a57d98e5db7 387 Pfam PF00155 Aminotransferase class I and II 29 377 2.6E-70 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_19435 75997fb6adff71af3fa08a57d98e5db7 387 SUPERFAMILY SSF53383 4 381 1.16E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_04990 b1fd99418dec79fbaa86701af5074ef5 327 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_04990 b1fd99418dec79fbaa86701af5074ef5 327 SUPERFAMILY SSF50331 239 326 4.19E-7 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I25_04990 b1fd99418dec79fbaa86701af5074ef5 327 SUPERFAMILY SSF52540 4 240 5.32E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_04990 b1fd99418dec79fbaa86701af5074ef5 327 Pfam PF00005 ABC transporter 23 162 7.4E-37 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_04990 b1fd99418dec79fbaa86701af5074ef5 327 SMART SM00382 29 212 8.9E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_04990 b1fd99418dec79fbaa86701af5074ef5 327 Gene3D G3DSA:3.40.50.300 1 239 8.9E-79 T 14-10-2018 C2I25_04990 b1fd99418dec79fbaa86701af5074ef5 327 Pfam PF08402 TOBE domain 248 325 2.3E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 C2I25_07760 1ce7febfaa5072c876c5473c54da8be1 383 Pfam PF13142 Domain of unknown function (DUF3960) 1 89 3.0E-61 T 14-10-2018 IPR025046 Domain of unknown function DUF3960 C2I25_07760 1ce7febfaa5072c876c5473c54da8be1 383 Pfam PF13112 Protein of unknown function (DUF3965) 91 381 1.4E-205 T 14-10-2018 IPR025087 Domain of unknown function DUF3965 C2I25_21475 93cdb92fa1af0dc1c6b0876ee090ae72 241 SUPERFAMILY SSF88713 37 238 1.31E-66 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_21475 93cdb92fa1af0dc1c6b0876ee090ae72 241 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 46 237 1.8E-73 T 14-10-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB C2I25_21475 93cdb92fa1af0dc1c6b0876ee090ae72 241 Gene3D G3DSA:3.20.20.370 34 241 3.8E-72 T 14-10-2018 C2I25_21475 93cdb92fa1af0dc1c6b0876ee090ae72 241 Pfam PF01522 Polysaccharide deacetylase 46 166 2.0E-34 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 556 7.4E-170 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 SUPERFAMILY SSF55190 6 115 4.84E-27 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 5.4E-25 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 5.4E-25 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 5.4E-25 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 5.4E-25 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 556 28.223 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 Gene3D G3DSA:1.10.730.10 432 556 1.1E-172 T 14-10-2018 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 SMART SM00836 437 556 5.3E-55 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 Gene3D G3DSA:3.30.1360.70 3 113 1.9E-27 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 94 4.2E-25 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 Pfam PF05746 DALR anticodon binding domain 438 556 2.3E-36 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 Pfam PF00750 tRNA synthetases class I (R) 107 404 3.1E-25 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 SUPERFAMILY SSF52374 118 448 2.17E-95 T 14-10-2018 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 Gene3D G3DSA:3.40.50.620 124 431 1.1E-172 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 SUPERFAMILY SSF47323 431 556 3.73E-35 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_12350 1ced48180f7cb8fa3ead49920508f122 556 SMART SM01016 5 95 6.6E-35 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_14860 14c36d9dd2f97a8a3e1be0f581cc73d8 256 SMART SM00422 7 76 1.2E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_14860 14c36d9dd2f97a8a3e1be0f581cc73d8 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 4.2E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_14860 14c36d9dd2f97a8a3e1be0f581cc73d8 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 4.2E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_14860 14c36d9dd2f97a8a3e1be0f581cc73d8 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 4.2E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_14860 14c36d9dd2f97a8a3e1be0f581cc73d8 256 Gene3D G3DSA:1.10.1660.10 5 141 1.6E-32 T 14-10-2018 C2I25_14860 14c36d9dd2f97a8a3e1be0f581cc73d8 256 Pfam PF13411 MerR HTH family regulatory protein 8 74 8.0E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_14860 14c36d9dd2f97a8a3e1be0f581cc73d8 256 Pfam PF07739 TipAS antibiotic-recognition domain 154 245 2.3E-8 T 14-10-2018 IPR012925 TipAS antibiotic-recognition domain C2I25_14860 14c36d9dd2f97a8a3e1be0f581cc73d8 256 SUPERFAMILY SSF46955 8 110 6.23E-25 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 Gene3D G3DSA:1.10.8.60 310 416 6.4E-37 T 14-10-2018 C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 4.0E-51 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 SMART SM00994 10 49 6.2E-24 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 406 1.9E-212 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 SUPERFAMILY SSF57716 11 46 1.57E-11 T 14-10-2018 C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 SMART SM00382 108 269 4.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.631 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 1.1E-17 T 14-10-2018 IPR019489 Clp ATPase, C-terminal C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 Pfam PF06689 ClpX C4-type zinc finger 12 48 4.8E-20 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 Gene3D G3DSA:3.30.50.30 3 50 1.4E-21 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 Gene3D G3DSA:3.40.50.300 53 309 1.4E-106 T 14-10-2018 C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 SMART SM01086 311 405 3.8E-33 T 14-10-2018 IPR019489 Clp ATPase, C-terminal C2I25_16920 954c6a94789e757c511f3e9397fc6d7a 419 SUPERFAMILY SSF52540 59 395 4.76E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 Gene3D G3DSA:3.30.565.10 202 357 4.9E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 Pfam PF00672 HAMP domain 71 118 1.1E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 SMART SM00388 130 197 2.6E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 SMART SM00304 70 122 5.4E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 130 191 2.7E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 SUPERFAMILY SSF55874 186 351 1.07E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 245 351 4.9E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 SUPERFAMILY SSF47384 113 196 1.49E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 SUPERFAMILY SSF158472 72 121 1.7E-9 T 14-10-2018 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 297 307 7.6E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 350 7.6E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 332 7.6E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 279 293 7.6E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 Gene3D G3DSA:1.20.1480.50 36 124 3.2E-14 T 14-10-2018 C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 SMART SM00387 242 353 3.4E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_02320 7c1ffdb7ed05d1e29df3bbc8781342d5 358 Gene3D G3DSA:1.10.287.130 125 201 2.2E-17 T 14-10-2018 C2I25_26010 5cdc09e6e2a4f44018f3024c0b7f2204 146 SUPERFAMILY SSF55811 3 144 1.35E-16 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_26010 5cdc09e6e2a4f44018f3024c0b7f2204 146 Pfam PF00293 NUDIX domain 27 131 3.2E-9 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_26010 5cdc09e6e2a4f44018f3024c0b7f2204 146 Gene3D G3DSA:3.90.79.10 1 146 2.1E-33 T 14-10-2018 C2I25_14890 e9bc07efe885abd1aa874e63144c4044 464 SUPERFAMILY SSF56322 29 460 2.09E-104 T 14-10-2018 IPR005801 ADC synthase GO:0009058 C2I25_14890 e9bc07efe885abd1aa874e63144c4044 464 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 110 458 4.7E-105 T 14-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 C2I25_14890 e9bc07efe885abd1aa874e63144c4044 464 Gene3D G3DSA:3.60.120.10 2 463 3.6E-105 T 14-10-2018 IPR005801 ADC synthase GO:0009058 C2I25_14890 e9bc07efe885abd1aa874e63144c4044 464 Pfam PF00425 chorismate binding enzyme 201 451 9.9E-73 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 Gene3D G3DSA:1.20.1250.20 3 394 5.6E-76 T 14-10-2018 C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 SUPERFAMILY SSF103473 8 393 2.35E-76 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 PRINTS PR01035 Tetracycline resistance protein signature 136 158 1.9E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 PRINTS PR01035 Tetracycline resistance protein signature 164 184 1.9E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 PRINTS PR01035 Tetracycline resistance protein signature 21 37 1.9E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 PRINTS PR01035 Tetracycline resistance protein signature 78 102 1.9E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 PRINTS PR01035 Tetracycline resistance protein signature 341 364 1.9E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 Pfam PF07690 Major Facilitator Superfamily 16 357 2.0E-56 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_07150 25ea6c819d8ae2b685410e169ba9e260 400 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_19860 32e5b806d21e873b10debaf1aeae9d4f 263 SUPERFAMILY SSF52151 1 257 5.23E-56 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I25_19860 32e5b806d21e873b10debaf1aeae9d4f 263 Pfam PF01734 Patatin-like phospholipase 8 73 1.5E-10 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I25_19860 32e5b806d21e873b10debaf1aeae9d4f 263 Pfam PF01734 Patatin-like phospholipase 124 164 2.7E-9 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I25_19860 32e5b806d21e873b10debaf1aeae9d4f 263 Gene3D G3DSA:3.40.1090.20 109 177 3.1E-6 T 14-10-2018 C2I25_19860 32e5b806d21e873b10debaf1aeae9d4f 263 Gene3D G3DSA:3.40.1090.10 1 105 7.9E-27 T 14-10-2018 C2I25_07390 c0d475782b892621d9633ad43c679b0b 362 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 358 1.5E-147 T 14-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic C2I25_07390 c0d475782b892621d9633ad43c679b0b 362 SUPERFAMILY SSF50891 246 358 1.06E-40 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_07390 c0d475782b892621d9633ad43c679b0b 362 SUPERFAMILY SSF51445 1 242 9.69E-96 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_07390 c0d475782b892621d9633ad43c679b0b 362 Gene3D G3DSA:3.20.20.70 1 241 1.1E-93 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_07390 c0d475782b892621d9633ad43c679b0b 362 Gene3D G3DSA:2.40.100.10 242 359 1.0E-42 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 Pfam PF01264 Chorismate synthase 1 364 1.3E-126 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 SUPERFAMILY SSF103263 1 388 1.28E-151 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 369 4.7E-133 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 PIRSF PIRSF001456 1 385 1.2E-134 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 37.194 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_03820 5504ab3e3e8e249adb9e8a331cefd352 390 Gene3D G3DSA:3.60.150.10 1 389 2.4E-158 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 Gene3D G3DSA:2.60.120.260 457 589 5.6E-45 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 SMART SM01276 74 370 2.4E-97 T 14-10-2018 IPR031161 Peptidase family M60 domain C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 Pfam PF17291 N-terminal domain of M60-like peptidases 71 149 5.5E-13 T 14-10-2018 IPR035423 M60-like domain, N-terminal C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 Gene3D G3DSA:1.10.390.30 293 456 2.9E-53 T 14-10-2018 C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 Gene3D G3DSA:1.10.1740.210 157 292 1.2E-37 T 14-10-2018 C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 Gene3D G3DSA:2.60.120.1250 36 156 7.8E-42 T 14-10-2018 C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 Pfam PF00754 F5/8 type C domain 465 586 7.3E-24 T 14-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 SUPERFAMILY SSF49785 453 590 1.7E-35 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily C2I25_02265 1fcba8ce245602de7d42880a7d69653c 591 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 151 420 1.0E-52 T 14-10-2018 IPR031161 Peptidase family M60 domain C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 Gene3D G3DSA:1.10.10.60 491 553 8.5E-15 T 14-10-2018 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 SMART SM00382 257 401 2.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 Pfam PF13596 PAS domain 103 201 1.9E-5 T 14-10-2018 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 Gene3D G3DSA:1.10.8.60 410 490 5.1E-23 T 14-10-2018 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 SUPERFAMILY SSF46689 451 552 2.69E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 451 460 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 Pfam PF00158 Sigma-54 interaction domain 238 404 1.1E-70 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 261 274 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 SUPERFAMILY SSF52540 239 480 1.81E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 SUPERFAMILY SSF55785 94 201 1.59E-9 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 Gene3D G3DSA:3.40.50.300 214 409 1.4E-66 T 14-10-2018 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 Pfam PF02954 Bacterial regulatory protein, Fis family 511 550 4.8E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 533 553 5.3E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 516 533 5.3E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 Gene3D G3DSA:3.30.450.20 90 201 1.1E-12 T 14-10-2018 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 324 339 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I25_25400 85eb2b14fa1f339f60a4981dde490432 553 SMART SM00091 98 163 0.0044 T 14-10-2018 IPR000014 PAS domain C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 SUPERFAMILY SSF54980 400 478 6.83E-26 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Gene3D G3DSA:3.30.70.240 602 672 2.5E-95 T 14-10-2018 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 SUPERFAMILY SSF54211 477 597 8.34E-43 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Pfam PF14492 Elongation Factor G, domain II 402 475 2.2E-36 T 14-10-2018 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 5.5E-71 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 SMART SM00838 598 685 2.9E-59 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 3.9E-44 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Pfam PF03764 Elongation factor G, domain IV 477 595 9.6E-47 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Gene3D G3DSA:2.40.30.10 292 403 1.4E-46 T 14-10-2018 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 SUPERFAMILY SSF50447 263 402 8.58E-37 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 SUPERFAMILY SSF52540 6 280 1.69E-112 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Pfam PF00679 Elongation factor G C-terminus 598 684 9.0E-33 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 SMART SM00889 478 596 1.3E-72 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Gene3D G3DSA:3.40.50.300 1 291 4.8E-113 T 14-10-2018 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Gene3D G3DSA:3.30.230.10 482 685 2.5E-95 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 2.6E-16 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 114.098 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 SUPERFAMILY SSF54980 598 688 1.63E-31 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 Gene3D G3DSA:3.30.70.870 404 481 1.1E-33 T 14-10-2018 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.7E-17 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.7E-17 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.7E-17 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.7E-17 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10990 3d7fe1310d18a14c9590177f3a95458c 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.7E-17 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_02550 e14904912b40b5a3c70a24a01f7d29b4 203 Pfam PF13761 Domain of unknown function (DUF4166) 16 199 2.4E-58 T 14-10-2018 IPR025311 Domain of unknown function DUF4166 C2I25_28420 f600c9f6cbcfc4ef7ba9d672f82dcaed 59 Pfam PF14162 YozD-like protein 1 56 6.5E-30 T 14-10-2018 IPR025545 YozD-like protein C2I25_28420 f600c9f6cbcfc4ef7ba9d672f82dcaed 59 ProDom PD052277 YOZD 1 56 1.0E-23 T 14-10-2018 C2I25_19900 769564b8a55abd59772cf3f5bae0cc11 538 Pfam PF10079 Bacillithiol biosynthesis BshC 1 535 1.4E-177 T 14-10-2018 IPR011199 Bacillithiol biosynthesis BshC C2I25_19900 769564b8a55abd59772cf3f5bae0cc11 538 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 538 31.814 T 14-10-2018 IPR011199 Bacillithiol biosynthesis BshC C2I25_19900 769564b8a55abd59772cf3f5bae0cc11 538 PIRSF PIRSF012535 1 538 2.3E-232 T 14-10-2018 IPR011199 Bacillithiol biosynthesis BshC C2I25_19900 769564b8a55abd59772cf3f5bae0cc11 538 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 10 536 3.3E-199 T 14-10-2018 IPR011199 Bacillithiol biosynthesis BshC C2I25_11055 71fa525d791937b1ebe61bdc877cda7e 48 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 48 7.3E-16 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11055 71fa525d791937b1ebe61bdc877cda7e 48 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 48 17.515 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11055 71fa525d791937b1ebe61bdc877cda7e 48 SUPERFAMILY SSF57829 1 48 4.09E-15 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 C2I25_11055 71fa525d791937b1ebe61bdc877cda7e 48 Pfam PF00471 Ribosomal protein L33 3 48 9.2E-18 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11055 71fa525d791937b1ebe61bdc877cda7e 48 Gene3D G3DSA:2.20.28.120 1 48 7.7E-18 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_01705 052c63838fd879e5d8e8ff777380ddbf 412 SUPERFAMILY SSF56801 101 405 5.1E-57 T 14-10-2018 C2I25_01705 052c63838fd879e5d8e8ff777380ddbf 412 Pfam PF13193 AMP-binding enzyme C-terminal domain 328 399 2.4E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_01705 052c63838fd879e5d8e8ff777380ddbf 412 ProSitePatterns PS00455 Putative AMP-binding domain signature. 107 118 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_01705 052c63838fd879e5d8e8ff777380ddbf 412 Gene3D G3DSA:3.30.300.30 313 409 2.7E-19 T 14-10-2018 C2I25_01705 052c63838fd879e5d8e8ff777380ddbf 412 Pfam PF00501 AMP-binding enzyme 83 279 1.9E-20 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_01705 052c63838fd879e5d8e8ff777380ddbf 412 Gene3D G3DSA:3.40.50.12780 1 306 1.2E-28 T 14-10-2018 C2I25_09530 e301bac050119640a674663fa259c2b5 433 Gene3D G3DSA:1.20.1250.20 21 433 2.6E-75 T 14-10-2018 C2I25_09530 e301bac050119640a674663fa259c2b5 433 SUPERFAMILY SSF103473 10 431 4.71E-80 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_09530 e301bac050119640a674663fa259c2b5 433 Pfam PF07690 Major Facilitator Superfamily 29 306 1.0E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_01530 bba50c6b022c527ce3427b3a2d7707f8 63 Pfam PF13035 Protein of unknown function (DUF3896) 1 61 4.5E-42 T 14-10-2018 IPR024994 Protein of unknown function DUF3896 C2I25_22100 ef1cdaf34dc7ddefba81c5f468df8cf1 660 Pfam PF00395 S-layer homology domain 481 524 1.7E-8 T 14-10-2018 IPR001119 S-layer homology domain C2I25_22100 ef1cdaf34dc7ddefba81c5f468df8cf1 660 Pfam PF00395 S-layer homology domain 543 584 8.1E-9 T 14-10-2018 IPR001119 S-layer homology domain C2I25_22100 ef1cdaf34dc7ddefba81c5f468df8cf1 660 Pfam PF00144 Beta-lactamase 46 366 1.2E-58 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_22100 ef1cdaf34dc7ddefba81c5f468df8cf1 660 Gene3D G3DSA:3.40.710.10 36 381 5.5E-84 T 14-10-2018 C2I25_22100 ef1cdaf34dc7ddefba81c5f468df8cf1 660 SUPERFAMILY SSF56601 44 366 3.93E-77 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_05035 b9a034f29e43c778286801d30ce33b1a 428 SUPERFAMILY SSF56601 4 286 1.13E-58 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_05035 b9a034f29e43c778286801d30ce33b1a 428 Gene3D G3DSA:2.60.410.10 301 377 3.5E-5 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_05035 b9a034f29e43c778286801d30ce33b1a 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 125 142 3.1E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_05035 b9a034f29e43c778286801d30ce33b1a 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 152 165 3.1E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_05035 b9a034f29e43c778286801d30ce33b1a 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 75 86 3.1E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_05035 b9a034f29e43c778286801d30ce33b1a 428 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 308 376 6.6E-5 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_05035 b9a034f29e43c778286801d30ce33b1a 428 Gene3D G3DSA:3.40.710.10 38 294 9.4E-71 T 14-10-2018 C2I25_05035 b9a034f29e43c778286801d30ce33b1a 428 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 46 266 2.9E-48 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_07720 16d440140225043d54e2d814e6c4ed32 206 Pfam PF02581 Thiamine monophosphate synthase 10 181 1.0E-39 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_07720 16d440140225043d54e2d814e6c4ed32 206 SUPERFAMILY SSF51391 8 199 1.44E-43 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_07720 16d440140225043d54e2d814e6c4ed32 206 Gene3D G3DSA:3.20.20.70 3 205 3.6E-49 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.6E-52 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.6E-52 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.6E-52 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.6E-52 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 1.6E-52 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 Pfam PF01467 Cytidylyltransferase-like 9 134 1.1E-20 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 78 8.0E-5 T 14-10-2018 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.34 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 3.7E-62 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 64 5.0E-18 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 SUPERFAMILY SSF52374 4 157 1.41E-44 T 14-10-2018 C2I25_19850 726da90d5b782a650819a3f454317b0e 163 Gene3D G3DSA:3.40.50.620 1 161 5.5E-60 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_14300 8196e1bdf251da9b591b6b958e6ace2a 210 SUPERFAMILY SSF46785 7 188 1.17E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_14300 8196e1bdf251da9b591b6b958e6ace2a 210 Gene3D G3DSA:1.10.10.10 4 89 3.2E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_14300 8196e1bdf251da9b591b6b958e6ace2a 210 Pfam PF01022 Bacterial regulatory protein, arsR family 10 52 2.3E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_18290 651db86dd64b598e1523e5f4f4f11e52 337 Gene3D G3DSA:3.80.30.30 111 337 1.2E-93 T 14-10-2018 C2I25_18290 651db86dd64b598e1523e5f4f4f11e52 337 Gene3D G3DSA:3.40.50.12110 1 110 5.1E-47 T 14-10-2018 C2I25_18290 651db86dd64b598e1523e5f4f4f11e52 337 SUPERFAMILY SSF102114 80 228 2.35E-5 T 14-10-2018 C2I25_18290 651db86dd64b598e1523e5f4f4f11e52 337 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 1 337 2.4E-161 T 14-10-2018 IPR023897 Spore photoproduct lyase GO:0003913 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 Gene3D G3DSA:3.30.470.20 223 361 1.4E-50 T 14-10-2018 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 Pfam PF07478 D-ala D-ala ligase C-terminus 143 344 4.6E-79 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 Gene3D G3DSA:3.40.50.20 1 123 3.8E-37 T 14-10-2018 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 290 318 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 PIRSF PIRSF039102 1 356 1.1E-115 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 347 1.8E-114 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 348 41.449 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 Gene3D G3DSA:3.30.1490.20 150 222 1.1E-29 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 102 113 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 Pfam PF01820 D-ala D-ala ligase N-terminus 5 124 7.7E-31 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 SUPERFAMILY SSF56059 135 351 7.6E-61 T 14-10-2018 C2I25_10300 c37439ae265991da2d3beb13220b0d17 361 SUPERFAMILY SSF52440 3 134 1.53E-34 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_08630 72520614992d0e4ff6f3d960d5cb6423 223 Gene3D G3DSA:1.10.10.10 126 223 3.1E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_08630 72520614992d0e4ff6f3d960d5cb6423 223 SUPERFAMILY SSF52172 1 125 4.27E-40 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_08630 72520614992d0e4ff6f3d960d5cb6423 223 SUPERFAMILY SSF46894 123 221 1.39E-25 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_08630 72520614992d0e4ff6f3d960d5cb6423 223 Gene3D G3DSA:3.40.50.2300 1 125 4.6E-37 T 14-10-2018 C2I25_08630 72520614992d0e4ff6f3d960d5cb6423 223 SMART SM00862 145 220 4.0E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_08630 72520614992d0e4ff6f3d960d5cb6423 223 SMART SM00448 1 111 1.5E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_08630 72520614992d0e4ff6f3d960d5cb6423 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 6.8E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_08630 72520614992d0e4ff6f3d960d5cb6423 223 Pfam PF00072 Response regulator receiver domain 4 112 1.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_19605 637672e6af750ac8d353337c0f22448b 70 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 8.0E-33 T 14-10-2018 IPR009907 Protein of unknown function DUF1447 C2I25_19605 637672e6af750ac8d353337c0f22448b 70 Hamap MF_01553 UPF0356 protein . 1 69 22.889 T 14-10-2018 IPR009907 Protein of unknown function DUF1447 C2I25_19605 637672e6af750ac8d353337c0f22448b 70 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 1.2E-27 T 14-10-2018 IPR009907 Protein of unknown function DUF1447 C2I25_19605 637672e6af750ac8d353337c0f22448b 70 Gene3D G3DSA:3.10.20.730 1 58 2.0E-26 T 14-10-2018 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 Gene3D G3DSA:1.10.260.40 3 58 4.7E-23 T 14-10-2018 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 SUPERFAMILY SSF47413 2 59 2.81E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 SUPERFAMILY SSF53822 58 287 2.57E-33 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 SMART SM00354 1 71 4.4E-28 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.0E-20 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 14-10-2018 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 Pfam PF13377 Periplasmic binding protein-like domain 154 282 2.5E-9 T 14-10-2018 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 Gene3D G3DSA:3.40.50.2300 62 281 3.8E-34 T 14-10-2018 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.8E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.8E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_18930 f1b9afb027f6946be56ac1759fc8181c 287 Gene3D G3DSA:3.40.50.2300 142 267 3.8E-34 T 14-10-2018 C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 71 83 - T 14-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 SUPERFAMILY SSF53335 2 409 4.98E-66 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 4 408 5.3E-71 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 Pfam PF00145 C-5 cytosine-specific DNA methylase 3 409 3.9E-68 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 390 408 - T 14-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 3 19 2.5E-14 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 113 127 2.5E-14 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 162 175 2.5E-14 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 C2I25_06775 67241e4ccb3b515b89b99b5d051e6365 427 Gene3D G3DSA:3.40.50.150 1 201 4.8E-54 T 14-10-2018 C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 SUPERFAMILY SSF52518 3 170 1.11E-48 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 8.8E-49 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 Gene3D G3DSA:3.40.50.970 337 550 3.2E-63 T 14-10-2018 C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 Gene3D G3DSA:3.40.50.970 3 180 6.7E-62 T 14-10-2018 C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 SUPERFAMILY SSF52518 358 553 3.4E-63 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 Gene3D G3DSA:3.40.50.1220 182 335 4.4E-49 T 14-10-2018 C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 526 4.5E-40 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 319 2.9E-35 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I25_28050 9cf234591780c84ebb0e2542692c40dc 566 SUPERFAMILY SSF52467 185 350 2.08E-46 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_13520 afb918025e000282d784868a4f0f8472 81 Gene3D G3DSA:3.40.30.10 1 75 1.5E-19 T 14-10-2018 C2I25_13520 afb918025e000282d784868a4f0f8472 81 Pfam PF05768 Glutaredoxin-like domain (DUF836) 2 60 2.3E-18 T 14-10-2018 IPR008554 Glutaredoxin-like C2I25_13520 afb918025e000282d784868a4f0f8472 81 SUPERFAMILY SSF52833 1 78 4.5E-21 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 6.5E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 6.5E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 6.5E-17 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 SUPERFAMILY SSF52768 3 359 2.88E-107 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 Gene3D G3DSA:3.40.800.20 2 353 3.7E-101 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 Pfam PF00850 Histone deacetylase domain 20 314 6.9E-77 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 349 368 1.3E-42 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 272 288 1.3E-42 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 311 330 1.3E-42 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 332 348 1.3E-42 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 1.3E-42 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 14 34 1.3E-42 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I25_15950 850e7338786ad4a99c9a144c6ea27631 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 1.3E-42 T 14-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 PIRSF PIRSF000106 25 398 2.6E-80 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 SUPERFAMILY SSF51735 163 393 2.98E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 PRINTS PR00072 Malic enzyme signature 190 206 7.4E-9 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 PRINTS PR00072 Malic enzyme signature 80 102 7.4E-9 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 PRINTS PR00072 Malic enzyme signature 159 175 7.4E-9 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 Gene3D G3DSA:3.40.50.10380 1 160 6.1E-74 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 Pfam PF03949 Malic enzyme, NAD binding domain 165 385 7.6E-25 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 SMART SM00919 163 386 8.8E-122 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 14-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 SMART SM01274 18 151 3.1E-81 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 Gene3D G3DSA:3.40.50.720 161 398 2.8E-81 T 14-10-2018 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 Pfam PF00390 Malic enzyme, N-terminal domain 20 151 1.6E-28 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I25_08590 281a99229ccb9d6b22df4a078df32f8c 399 SUPERFAMILY SSF53223 10 161 1.94E-55 T 14-10-2018 C2I25_01515 21d1fd6782bd6108156072098fb5b2f1 300 Pfam PF00248 Aldo/keto reductase family 15 290 1.6E-60 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_01515 21d1fd6782bd6108156072098fb5b2f1 300 SUPERFAMILY SSF51430 8 295 1.57E-74 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_01515 21d1fd6782bd6108156072098fb5b2f1 300 PRINTS PR00069 Aldo-keto reductase signature 112 130 1.4E-7 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_01515 21d1fd6782bd6108156072098fb5b2f1 300 PRINTS PR00069 Aldo-keto reductase signature 143 160 1.4E-7 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_01515 21d1fd6782bd6108156072098fb5b2f1 300 Gene3D G3DSA:3.20.20.100 3 300 1.7E-101 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_13240 5a4ae8b70b12fd7e248227f1baa58909 374 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 89 239 5.8E-52 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_13240 5a4ae8b70b12fd7e248227f1baa58909 374 Gene3D G3DSA:1.10.260.150 52 355 6.3E-94 T 14-10-2018 C2I25_13240 5a4ae8b70b12fd7e248227f1baa58909 374 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 239 7.3E-51 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_16815 13fb7e1305141534d4ade18a05c2852c 413 SUPERFAMILY SSF51556 66 370 1.36E-74 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_16815 13fb7e1305141534d4ade18a05c2852c 413 Pfam PF07969 Amidohydrolase family 55 401 6.4E-38 T 14-10-2018 IPR013108 Amidohydrolase 3 C2I25_16815 13fb7e1305141534d4ade18a05c2852c 413 Gene3D G3DSA:3.20.20.140 66 360 3.7E-115 T 14-10-2018 C2I25_16815 13fb7e1305141534d4ade18a05c2852c 413 Gene3D G3DSA:2.30.40.10 28 400 3.7E-115 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_27300 6bcb5711a9e94742b1cb5af0ab04e445 409 SUPERFAMILY SSF46689 306 354 4.48E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_27300 6bcb5711a9e94742b1cb5af0ab04e445 409 SMART SM00342 320 403 1.8E-31 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_27300 6bcb5711a9e94742b1cb5af0ab04e445 409 Pfam PF12833 Helix-turn-helix domain 326 404 3.0E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_27300 6bcb5711a9e94742b1cb5af0ab04e445 409 SUPERFAMILY SSF46689 357 406 2.91E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_27300 6bcb5711a9e94742b1cb5af0ab04e445 409 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 357 399 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I25_27300 6bcb5711a9e94742b1cb5af0ab04e445 409 Gene3D G3DSA:1.10.10.60 354 407 4.9E-18 T 14-10-2018 C2I25_27300 6bcb5711a9e94742b1cb5af0ab04e445 409 Gene3D G3DSA:1.10.10.60 301 353 6.3E-16 T 14-10-2018 C2I25_18295 b93b1f030c8856fcb42efc9a56f16a37 142 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 123 7.7E-18 T 14-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 C2I25_18295 b93b1f030c8856fcb42efc9a56f16a37 142 SMART SM00529 24 123 7.1E-44 T 14-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 C2I25_18295 b93b1f030c8856fcb42efc9a56f16a37 142 SUPERFAMILY SSF46785 3 62 3.97E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_18295 b93b1f030c8856fcb42efc9a56f16a37 142 SUPERFAMILY SSF47979 63 130 3.06E-18 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 C2I25_18295 b93b1f030c8856fcb42efc9a56f16a37 142 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 60 6.8E-25 T 14-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 C2I25_18295 b93b1f030c8856fcb42efc9a56f16a37 142 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 48.072 T 14-10-2018 IPR022897 HTH-type transcription regulator MntR C2I25_18295 b93b1f030c8856fcb42efc9a56f16a37 142 Gene3D G3DSA:1.10.60.10 74 142 7.5E-33 T 14-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 C2I25_18295 b93b1f030c8856fcb42efc9a56f16a37 142 Gene3D G3DSA:1.10.10.10 1 73 2.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23580 43bcf00b09e0524fa2fcf488e8f59c78 370 Gene3D G3DSA:3.40.1830.10 1 162 2.6E-11 T 14-10-2018 IPR035097 Peptidase M29, N-terminal C2I25_23580 43bcf00b09e0524fa2fcf488e8f59c78 370 SUPERFAMILY SSF144052 2 358 2.35E-98 T 14-10-2018 C2I25_23580 43bcf00b09e0524fa2fcf488e8f59c78 370 Pfam PF02073 Thermophilic metalloprotease (M29) 3 334 5.5E-57 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Pfam PF00874 PRD domain 313 401 9.4E-21 T 14-10-2018 IPR011608 PRD domain GO:0006355 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Pfam PF00874 PRD domain 207 286 4.0E-14 T 14-10-2018 IPR011608 PRD domain GO:0006355 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Pfam PF08279 HTH domain 7 64 5.6E-12 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Gene3D G3DSA:3.40.50.2300 412 502 1.5E-8 T 14-10-2018 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Gene3D G3DSA:1.10.10.10 1 157 1.6E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Gene3D G3DSA:3.40.930.10 504 644 5.6E-30 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Gene3D G3DSA:1.10.1790.10 190 290 1.2E-12 T 14-10-2018 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Pfam PF05043 Mga helix-turn-helix domain 89 169 1.2E-10 T 14-10-2018 IPR007737 Mga helix-turn-helix domain C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 SUPERFAMILY SSF55804 505 645 4.19E-31 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 SUPERFAMILY SSF63520 189 286 3.66E-15 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 508 644 1.2E-29 T 14-10-2018 IPR002178 PTS EIIA type-2 domain C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 SUPERFAMILY SSF52794 411 498 8.89E-7 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 SUPERFAMILY SSF63520 302 403 5.1E-23 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I25_07385 c3050c3fdf20f6a929410b713427455b 646 Gene3D G3DSA:1.10.1790.10 304 403 7.5E-21 T 14-10-2018 C2I25_20690 d1e4854fe858e3604ae5b0511927cbe1 639 Gene3D G3DSA:3.40.720.10 241 548 5.6E-74 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_20690 d1e4854fe858e3604ae5b0511927cbe1 639 Pfam PF00884 Sulfatase 248 538 5.4E-38 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I25_20690 d1e4854fe858e3604ae5b0511927cbe1 639 SUPERFAMILY SSF53649 246 619 8.78E-73 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_20690 d1e4854fe858e3604ae5b0511927cbe1 639 PIRSF PIRSF005091 1 623 3.5E-173 T 14-10-2018 IPR012160 Lipoteichoic acid synthase-like C2I25_16285 04efec92dfd0f306625713e19f05e28c 214 Gene3D G3DSA:1.10.10.10 2 72 1.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_16285 04efec92dfd0f306625713e19f05e28c 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 3.5E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_16285 04efec92dfd0f306625713e19f05e28c 214 SUPERFAMILY SSF48008 93 209 6.02E-5 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I25_16285 04efec92dfd0f306625713e19f05e28c 214 SUPERFAMILY SSF46785 4 86 5.55E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_16285 04efec92dfd0f306625713e19f05e28c 214 Gene3D G3DSA:1.20.120.530 79 213 5.6E-6 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I25_16285 04efec92dfd0f306625713e19f05e28c 214 SMART SM00345 12 71 5.1E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_16285 04efec92dfd0f306625713e19f05e28c 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 9.8E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_16285 04efec92dfd0f306625713e19f05e28c 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 9.8E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 Pfam PF04542 Sigma-70 region 2 142 211 3.7E-22 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 138 363 3.2E-39 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 Pfam PF04545 Sigma-70, region 4 310 363 5.2E-20 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 138 374 1.1E-124 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 C2I25_17825 1271be14715514102c560266c26f5747 375 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 11 375 34.044 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 C2I25_17825 1271be14715514102c560266c26f5747 375 Pfam PF00140 Sigma-70 factor, region 1.2 104 137 8.4E-18 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_17825 1271be14715514102c560266c26f5747 375 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 335 361 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 Gene3D G3DSA:1.10.601.10 137 214 8.4E-51 T 14-10-2018 C2I25_17825 1271be14715514102c560266c26f5747 375 Gene3D G3DSA:1.10.601.10 102 136 3.0E-11 T 14-10-2018 C2I25_17825 1271be14715514102c560266c26f5747 375 Pfam PF04539 Sigma-70 region 3 221 297 1.4E-31 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 Gene3D G3DSA:1.10.10.10 215 290 8.1E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17825 1271be14715514102c560266c26f5747 375 SUPERFAMILY SSF88659 215 288 2.43E-22 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_17825 1271be14715514102c560266c26f5747 375 Gene3D G3DSA:1.10.220.120 15 75 3.2E-9 T 14-10-2018 C2I25_17825 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 314 326 3.2E-32 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 190 198 3.2E-32 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 335 350 3.2E-32 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 166 179 3.2E-32 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 350 361 3.2E-32 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 166 179 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 Pfam PF03979 Sigma-70 factor, region 1.1 17 81 5.4E-16 T 14-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 C2I25_17825 1271be14715514102c560266c26f5747 375 Gene3D G3DSA:1.10.10.10 291 375 2.2E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17825 1271be14715514102c560266c26f5747 375 SUPERFAMILY SSF88659 272 373 4.11E-30 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_17825 1271be14715514102c560266c26f5747 375 SUPERFAMILY SSF88946 103 212 1.96E-54 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_00015 09e7a77b06cc20ddf77b6e651571a08e 130 PIRSF PIRSF034303 1 130 2.1E-49 T 14-10-2018 IPR012543 Protein of unknown function DUF1694 C2I25_00015 09e7a77b06cc20ddf77b6e651571a08e 130 Pfam PF07997 Protein of unknown function (DUF1694) 4 119 6.5E-39 T 14-10-2018 IPR012543 Protein of unknown function DUF1694 C2I25_00015 09e7a77b06cc20ddf77b6e651571a08e 130 Gene3D G3DSA:3.30.1330.30 1 130 7.0E-46 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_00015 09e7a77b06cc20ddf77b6e651571a08e 130 SUPERFAMILY SSF160515 4 127 1.7E-39 T 14-10-2018 C2I25_28490 09e7a77b06cc20ddf77b6e651571a08e 130 PIRSF PIRSF034303 1 130 2.1E-49 T 14-10-2018 IPR012543 Protein of unknown function DUF1694 C2I25_28490 09e7a77b06cc20ddf77b6e651571a08e 130 Pfam PF07997 Protein of unknown function (DUF1694) 4 119 6.5E-39 T 14-10-2018 IPR012543 Protein of unknown function DUF1694 C2I25_28490 09e7a77b06cc20ddf77b6e651571a08e 130 Gene3D G3DSA:3.30.1330.30 1 130 7.0E-46 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_28490 09e7a77b06cc20ddf77b6e651571a08e 130 SUPERFAMILY SSF160515 4 127 1.7E-39 T 14-10-2018 C2I25_28535 09e7a77b06cc20ddf77b6e651571a08e 130 PIRSF PIRSF034303 1 130 2.1E-49 T 14-10-2018 IPR012543 Protein of unknown function DUF1694 C2I25_28535 09e7a77b06cc20ddf77b6e651571a08e 130 Pfam PF07997 Protein of unknown function (DUF1694) 4 119 6.5E-39 T 14-10-2018 IPR012543 Protein of unknown function DUF1694 C2I25_28535 09e7a77b06cc20ddf77b6e651571a08e 130 Gene3D G3DSA:3.30.1330.30 1 130 7.0E-46 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_28535 09e7a77b06cc20ddf77b6e651571a08e 130 SUPERFAMILY SSF160515 4 127 1.7E-39 T 14-10-2018 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 ProSitePatterns PS00786 5'-nucleotidase signature 2. 114 125 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 Gene3D G3DSA:3.90.780.10 345 528 1.2E-58 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 Pfam PF00149 Calcineurin-like phosphoesterase 41 269 9.8E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 Gene3D G3DSA:3.60.21.10 35 341 1.2E-85 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 SUPERFAMILY SSF56300 33 341 2.17E-81 T 14-10-2018 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 Pfam PF02872 5'-nucleotidase, C-terminal domain 342 490 1.2E-48 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 SUPERFAMILY SSF55816 339 528 4.05E-57 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 PRINTS PR01607 Apyrase family signature 36 54 8.9E-26 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 PRINTS PR01607 Apyrase family signature 251 274 8.9E-26 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 PRINTS PR01607 Apyrase family signature 465 484 8.9E-26 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 PRINTS PR01607 Apyrase family signature 277 297 8.9E-26 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 PRINTS PR01607 Apyrase family signature 394 417 8.9E-26 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18950 3ea5f6be3073f56aa5dc9be03c8e4dd4 529 PRINTS PR01607 Apyrase family signature 222 239 8.9E-26 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Pfam PF00231 ATP synthase 3 285 1.8E-99 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 285 3.4E-108 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 PRINTS PR00126 ATP synthase gamma subunit signature 263 284 7.9E-40 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 7.9E-40 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 PRINTS PR00126 ATP synthase gamma subunit signature 232 251 7.9E-40 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 7.9E-40 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Gene3D G3DSA:1.10.287.80 6 281 4.9E-102 T 14-10-2018 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 271 284 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 SUPERFAMILY SSF52943 2 285 1.57E-90 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 285 35.93 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12650 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Gene3D G3DSA:3.40.1380.10 61 204 4.9E-102 T 14-10-2018 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 Gene3D G3DSA:3.40.1550.10 239 433 1.6E-45 T 14-10-2018 IPR028976 CheC-like superfamily C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 Gene3D G3DSA:3.40.1550.10 20 215 3.2E-45 T 14-10-2018 IPR028976 CheC-like superfamily C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 476 543 4.7E-17 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 SUPERFAMILY SSF103039 239 430 1.24E-45 T 14-10-2018 IPR028976 CheC-like superfamily C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 PRINTS PR00956 Flagellar motor switch protein FliN signature 492 508 1.2E-7 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 PRINTS PR00956 Flagellar motor switch protein FliN signature 521 536 1.2E-7 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 PRINTS PR00956 Flagellar motor switch protein FliN signature 508 521 1.2E-7 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 PRINTS PR00956 Flagellar motor switch protein FliN signature 475 491 1.2E-7 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 SUPERFAMILY SSF101801 473 543 2.09E-15 T 14-10-2018 IPR036429 SpoA-like superfamily C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF04509 CheC-like family 122 158 5.2E-15 T 14-10-2018 IPR007597 CheC-like protein GO:0016787 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF04509 CheC-like family 26 60 3.0E-11 T 14-10-2018 IPR007597 CheC-like protein GO:0016787 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF04509 CheC-like family 342 377 8.3E-13 T 14-10-2018 IPR007597 CheC-like protein GO:0016787 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF04509 CheC-like family 244 279 9.3E-11 T 14-10-2018 IPR007597 CheC-like protein GO:0016787 C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 Gene3D G3DSA:2.30.330.10 462 545 4.0E-18 T 14-10-2018 IPR036429 SpoA-like superfamily C2I25_03210 f233f1ab9c841448b8d01403b2e4f795 545 SUPERFAMILY SSF103039 20 211 4.19E-45 T 14-10-2018 IPR028976 CheC-like superfamily C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Pfam PF09371 Tex-like protein N-terminal domain 17 199 3.4E-71 T 14-10-2018 IPR018974 Tex-like protein, N-terminal C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 SUPERFAMILY SSF53098 320 467 3.57E-49 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 SUPERFAMILY SSF47781 468 554 5.45E-26 T 14-10-2018 IPR010994 RuvA domain 2-like C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Gene3D G3DSA:1.10.150.310 497 631 8.9E-45 T 14-10-2018 C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Gene3D G3DSA:3.30.420.140 323 449 2.1E-154 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 SUPERFAMILY SSF50249 636 722 8.21E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Gene3D G3DSA:1.10.10.650 6 116 1.7E-37 T 14-10-2018 IPR023319 Tex-like protein, HTH domain superfamily C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 SMART SM00316 650 721 4.5E-22 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Pfam PF12836 Helix-hairpin-helix motif 489 553 6.0E-26 T 14-10-2018 C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Gene3D G3DSA:1.10.3500.10 119 496 2.1E-154 T 14-10-2018 IPR023323 Tex-like domain superfamily C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 SUPERFAMILY SSF47781 559 633 1.69E-14 T 14-10-2018 IPR010994 RuvA domain 2-like C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 SUPERFAMILY SSF158832 11 319 3.01E-115 T 14-10-2018 C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 SMART SM00732 324 422 8.0E-32 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Pfam PF00575 S1 RNA binding domain 650 720 1.3E-16 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Gene3D G3DSA:2.40.50.140 635 722 2.5E-25 T 14-10-2018 C2I25_10250 b1e09626d761ae49699cccc2dcf09aad 724 Pfam PF16921 Tex protein YqgF-like domain 324 449 8.3E-56 T 14-10-2018 IPR032639 Tex protein, YqgF-like domain C2I25_16975 295a3a9c3b2107309b51bf877191fe24 428 Gene3D G3DSA:3.90.1150.10 10 421 3.4E-184 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_16975 295a3a9c3b2107309b51bf877191fe24 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 106.59 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 C2I25_16975 295a3a9c3b2107309b51bf877191fe24 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 425 3.0E-200 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 C2I25_16975 295a3a9c3b2107309b51bf877191fe24 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_16975 295a3a9c3b2107309b51bf877191fe24 428 SUPERFAMILY SSF53383 4 426 1.79E-131 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_16975 295a3a9c3b2107309b51bf877191fe24 428 Gene3D G3DSA:3.40.640.10 72 319 3.4E-184 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_16975 295a3a9c3b2107309b51bf877191fe24 428 Pfam PF00202 Aminotransferase class-III 35 394 3.2E-76 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_26600 54c6dbd0154adf67311344b7b7f10652 413 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 33 366 2.2E-37 T 14-10-2018 IPR006427 Phage portal protein, HK97 C2I25_26600 54c6dbd0154adf67311344b7b7f10652 413 Pfam PF04860 Phage portal protein 40 362 7.3E-32 T 14-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 PIRSF PIRSF001174 1 775 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:2.30.130.40 5 117 5.7E-30 T 14-10-2018 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:1.20.58.1480 120 245 3.9E-41 T 14-10-2018 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:3.40.50.300 314 491 2.5E-69 T 14-10-2018 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 SUPERFAMILY SSF52540 313 588 8.16E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 SUPERFAMILY SSF88697 11 201 1.54E-44 T 14-10-2018 IPR015947 PUA-like superfamily C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 11 201 9.4E-40 T 14-10-2018 IPR003111 Lon, substrate-binding domain C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 489 3.9E-24 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:1.10.8.60 492 584 5.3E-33 T 14-10-2018 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 SUPERFAMILY SSF54211 595 770 1.4E-55 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:3.30.230.10 593 776 1.3E-84 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 8.3E-98 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 SMART SM00464 10 202 1.7E-68 T 14-10-2018 IPR003111 Lon, substrate-binding domain C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 TIGRFAM TIGR00763 lon: endopeptidase La 12 771 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 SMART SM00382 348 493 1.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 Hamap MF_01973 Lon protease [lon]. 11 772 72.904 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 6.3E-53 T 14-10-2018 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 6.3E-53 T 14-10-2018 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 6.3E-53 T 14-10-2018 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 6.3E-53 T 14-10-2018 C2I25_16930 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 6.3E-53 T 14-10-2018 C2I25_04550 7fc526e5b976b9a673d762793115b7b5 389 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 374 1.2E-111 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_04550 7fc526e5b976b9a673d762793115b7b5 389 PIRSF PIRSF005962 6 389 2.3E-127 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_04550 7fc526e5b976b9a673d762793115b7b5 389 Pfam PF07687 Peptidase dimerisation domain 186 278 2.4E-11 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_04550 7fc526e5b976b9a673d762793115b7b5 389 Gene3D G3DSA:3.30.70.360 181 295 3.7E-136 T 14-10-2018 C2I25_04550 7fc526e5b976b9a673d762793115b7b5 389 Pfam PF01546 Peptidase family M20/M25/M40 72 381 3.8E-32 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_04550 7fc526e5b976b9a673d762793115b7b5 389 Gene3D G3DSA:3.40.630.10 14 372 3.7E-136 T 14-10-2018 C2I25_04550 7fc526e5b976b9a673d762793115b7b5 389 SUPERFAMILY SSF53187 12 388 5.66E-78 T 14-10-2018 C2I25_04550 7fc526e5b976b9a673d762793115b7b5 389 SUPERFAMILY SSF55031 181 298 5.1E-29 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_03970 9ad74c8f481f421c545481055c149978 159 Pfam PF01476 LysM domain 104 149 1.7E-11 T 14-10-2018 IPR018392 LysM domain C2I25_03970 9ad74c8f481f421c545481055c149978 159 SMART SM00257 103 149 2.1E-11 T 14-10-2018 IPR018392 LysM domain C2I25_03970 9ad74c8f481f421c545481055c149978 159 SUPERFAMILY SSF54106 102 149 2.35E-8 T 14-10-2018 C2I25_03970 9ad74c8f481f421c545481055c149978 159 Gene3D G3DSA:3.10.350.10 88 159 2.9E-17 T 14-10-2018 IPR036779 LysM domain superfamily C2I25_02305 4ba2c03e902a0c76e8f0eee52dccfb99 319 Pfam PF00581 Rhodanese-like domain 118 212 4.7E-11 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_02305 4ba2c03e902a0c76e8f0eee52dccfb99 319 SMART SM00450 117 218 1.6E-18 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_02305 4ba2c03e902a0c76e8f0eee52dccfb99 319 SUPERFAMILY SSF52821 90 248 4.12E-36 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_02305 4ba2c03e902a0c76e8f0eee52dccfb99 319 Gene3D G3DSA:3.40.250.10 104 253 3.2E-45 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_02305 4ba2c03e902a0c76e8f0eee52dccfb99 319 Gene3D G3DSA:3.30.70.100 2 99 3.0E-29 T 14-10-2018 C2I25_02305 4ba2c03e902a0c76e8f0eee52dccfb99 319 Hamap MF_00469 UPF0176 protein YceA [yceA]. 5 269 39.304 T 14-10-2018 IPR020936 Uncharacterised protein family UPF0176 C2I25_02305 4ba2c03e902a0c76e8f0eee52dccfb99 319 Pfam PF12368 Rhodanase C-terminal 224 290 1.6E-14 T 14-10-2018 IPR022111 Rhodanase, C-terminal C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 2.7E-47 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 SUPERFAMILY SSF51735 136 303 3.19E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 4.9E-83 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 Gene3D G3DSA:3.40.50.720 129 305 2.9E-141 T 14-10-2018 C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 PIRSF PIRSF000183 1 371 1.8E-193 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 SMART SM01002 148 297 6.6E-90 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 SMART SM01003 4 136 8.4E-79 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 Gene3D G3DSA:3.40.50.720 3 353 2.9E-141 T 14-10-2018 C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 SUPERFAMILY SSF52283 1 360 1.45E-68 T 14-10-2018 C2I25_16180 11edd7f9876d2f889b7e90f7beebfc04 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 4.6E-182 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 C2I25_01835 2b788f688682d3b2164f094033ccc170 586 SUPERFAMILY SSF52540 333 578 4.76E-90 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01835 2b788f688682d3b2164f094033ccc170 586 Pfam PF00664 ABC transporter transmembrane region 31 298 1.9E-46 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_01835 2b788f688682d3b2164f094033ccc170 586 Gene3D G3DSA:1.20.1560.10 1 330 9.1E-81 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_01835 2b788f688682d3b2164f094033ccc170 586 SMART SM00382 367 554 1.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_01835 2b788f688682d3b2164f094033ccc170 586 Pfam PF00005 ABC transporter 358 508 4.9E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_01835 2b788f688682d3b2164f094033ccc170 586 Gene3D G3DSA:3.40.50.300 342 582 7.4E-91 T 14-10-2018 C2I25_01835 2b788f688682d3b2164f094033ccc170 586 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_01835 2b788f688682d3b2164f094033ccc170 586 SUPERFAMILY SSF90123 18 325 1.06E-72 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_22850 5a13bbd13afd63a18ca1b00f5928b6e0 245 Pfam PF00925 GTP cyclohydrolase II 72 214 7.6E-47 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_22850 5a13bbd13afd63a18ca1b00f5928b6e0 245 SUPERFAMILY SSF142695 70 217 7.45E-46 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_22850 5a13bbd13afd63a18ca1b00f5928b6e0 245 Gene3D G3DSA:3.40.50.10990 58 217 2.3E-53 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_11720 0691c9408547b4a0ba64425c6c68b231 96 SUPERFAMILY SSF54995 1 95 1.57E-35 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11720 0691c9408547b4a0ba64425c6c68b231 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 14-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I25_11720 0691c9408547b4a0ba64425c6c68b231 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.4E-33 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11720 0691c9408547b4a0ba64425c6c68b231 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 24.045 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I25_11720 0691c9408547b4a0ba64425c6c68b231 96 Gene3D G3DSA:3.30.70.60 1 96 9.6E-37 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 C2I25_11720 0691c9408547b4a0ba64425c6c68b231 96 Pfam PF01250 Ribosomal protein S6 3 92 1.7E-30 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_19550 9687d8553fbc30dbfd63b8d2167d1482 78 SUPERFAMILY SSF143567 2 77 1.16E-27 T 14-10-2018 IPR038073 YkuJ-like superfamily C2I25_19550 9687d8553fbc30dbfd63b8d2167d1482 78 PIRSF PIRSF037356 1 78 5.7E-36 T 14-10-2018 IPR014904 Protein of unknown function DUF1797 C2I25_19550 9687d8553fbc30dbfd63b8d2167d1482 78 Pfam PF08796 Protein of unknown function (DUF1797) 7 77 2.0E-27 T 14-10-2018 IPR014904 Protein of unknown function DUF1797 C2I25_19550 9687d8553fbc30dbfd63b8d2167d1482 78 Gene3D G3DSA:3.30.720.20 1 78 1.3E-33 T 14-10-2018 IPR038073 YkuJ-like superfamily C2I25_20535 b4dd2389dc8ef793647d0d9ecec5bd37 67 Pfam PF14035 YlzJ-like protein 3 65 9.0E-22 T 14-10-2018 IPR025619 YlzJ-like protein C2I25_20580 81d9223d14293ddc33e4b4dd2142157c 428 Gene3D G3DSA:3.30.830.10 7 237 1.6E-61 T 14-10-2018 C2I25_20580 81d9223d14293ddc33e4b4dd2142157c 428 Pfam PF00675 Insulinase (Peptidase family M16) 64 150 5.8E-16 T 14-10-2018 IPR011765 Peptidase M16, N-terminal C2I25_20580 81d9223d14293ddc33e4b4dd2142157c 428 Gene3D G3DSA:3.30.830.10 238 426 1.3E-44 T 14-10-2018 C2I25_20580 81d9223d14293ddc33e4b4dd2142157c 428 Pfam PF05193 Peptidase M16 inactive domain 181 361 4.0E-19 T 14-10-2018 IPR007863 Peptidase M16, C-terminal C2I25_20580 81d9223d14293ddc33e4b4dd2142157c 428 SUPERFAMILY SSF63411 242 426 3.67E-19 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I25_20580 81d9223d14293ddc33e4b4dd2142157c 428 SUPERFAMILY SSF63411 13 219 5.41E-42 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I25_17435 71086b518d2d4b4a4a8bcbac1affcfbd 315 Pfam PF01497 Periplasmic binding protein 62 289 8.5E-35 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_17435 71086b518d2d4b4a4a8bcbac1affcfbd 315 Gene3D G3DSA:3.40.50.1980 35 131 3.4E-16 T 14-10-2018 C2I25_17435 71086b518d2d4b4a4a8bcbac1affcfbd 315 SUPERFAMILY SSF53807 42 309 5.1E-58 T 14-10-2018 C2I25_17435 71086b518d2d4b4a4a8bcbac1affcfbd 315 Gene3D G3DSA:3.40.50.1980 141 312 1.5E-50 T 14-10-2018 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 Pfam PF00905 Penicillin binding protein transpeptidase domain 257 564 1.5E-83 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 Pfam PF03717 Penicillin-binding Protein dimerisation domain 57 207 2.5E-18 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 Gene3D G3DSA:2.20.70.70 55 212 1.5E-39 T 14-10-2018 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 Gene3D G3DSA:3.40.710.10 222 574 1.9E-100 T 14-10-2018 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 SUPERFAMILY SSF56519 55 228 4.32E-38 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 SUPERFAMILY SSF54184 586 644 4.06E-11 T 14-10-2018 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 SMART SM00740 646 701 0.07 T 14-10-2018 IPR005543 PASTA domain C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 SMART SM00740 586 645 0.0073 T 14-10-2018 IPR005543 PASTA domain C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 SUPERFAMILY SSF56601 180 580 6.54E-90 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 Gene3D G3DSA:3.90.1310.10 58 195 1.5E-39 T 14-10-2018 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 Pfam PF03793 PASTA domain 647 699 2.7E-8 T 14-10-2018 IPR005543 PASTA domain C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 Pfam PF03793 PASTA domain 591 641 6.9E-7 T 14-10-2018 IPR005543 PASTA domain C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 SUPERFAMILY SSF54184 647 699 7.46E-12 T 14-10-2018 C2I25_26310 387a1f5990bdf77288ba827df61307e8 712 Gene3D G3DSA:3.30.70.2110 77 151 1.5E-39 T 14-10-2018 C2I25_26070 5b3172b2f1d8101893d31fc1c5c101f6 173 Pfam PF12867 DinB superfamily 33 164 7.0E-13 T 14-10-2018 IPR024775 DinB-like domain C2I25_26070 5b3172b2f1d8101893d31fc1c5c101f6 173 Gene3D G3DSA:1.20.120.450 1 173 1.1E-50 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_26070 5b3172b2f1d8101893d31fc1c5c101f6 173 SUPERFAMILY SSF109854 3 173 5.34E-49 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_26070 5b3172b2f1d8101893d31fc1c5c101f6 173 Hamap MF_01256 Putative metal-dependent hydrolase . 2 173 40.76 T 14-10-2018 IPR023774 Putative metal-dependent hydrolase YfiT C2I25_07500 7614e8d2a6443556f1c5965c8d607729 186 SUPERFAMILY SSF55469 8 179 4.97E-35 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_07500 7614e8d2a6443556f1c5965c8d607729 186 Pfam PF00881 Nitroreductase family 11 164 7.1E-28 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_07500 7614e8d2a6443556f1c5965c8d607729 186 Gene3D G3DSA:3.40.109.10 1 186 5.0E-52 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_25395 7ed856911a572048b3f62046193ffc89 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 8 59 1.3E-11 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain C2I25_25395 7ed856911a572048b3f62046193ffc89 90 Gene3D G3DSA:1.10.10.1100 1 66 5.0E-16 T 14-10-2018 C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 321 333 2.9E-31 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 238 2.9E-31 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 263 2.9E-31 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 371 387 2.9E-31 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 425 442 2.9E-31 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 320 331 - T 14-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 Gene3D G3DSA:1.10.940.10 1 140 6.9E-40 T 14-10-2018 IPR035926 NusB-like superfamily C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 Gene3D G3DSA:3.40.50.150 142 442 1.2E-85 T 14-10-2018 C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 Pfam PF01029 NusB family 4 125 7.2E-32 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 6 443 8.8E-149 T 14-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 SUPERFAMILY SSF48013 2 127 4.06E-39 T 14-10-2018 IPR035926 NusB-like superfamily C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 SUPERFAMILY SSF53335 136 443 4.6E-76 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_20180 e4fd4bb52d1b7c57c8b03fd55d7a9451 444 Pfam PF01189 16S rRNA methyltransferase RsmB/F 242 441 1.2E-59 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 C2I25_04645 eaf69cc9dbb52251670a5f2122db1d03 322 Pfam PF00268 Ribonucleotide reductase, small chain 4 281 3.1E-79 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04645 eaf69cc9dbb52251670a5f2122db1d03 322 PIRSF PIRSF000355 1 316 3.7E-85 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04645 eaf69cc9dbb52251670a5f2122db1d03 322 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 1 320 4.4E-143 T 14-10-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_04645 eaf69cc9dbb52251670a5f2122db1d03 322 Gene3D G3DSA:1.10.620.20 1 290 4.5E-112 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 C2I25_04645 eaf69cc9dbb52251670a5f2122db1d03 322 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 92 108 - T 14-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04645 eaf69cc9dbb52251670a5f2122db1d03 322 SUPERFAMILY SSF47240 2 318 3.1E-91 T 14-10-2018 IPR009078 Ferritin-like superfamily C2I25_16825 cb8957cb8654812e171c05b44751e641 74 SUPERFAMILY SSF46894 7 72 4.76E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_16825 cb8957cb8654812e171c05b44751e641 74 Gene3D G3DSA:1.10.10.10 1 74 8.0E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_16825 cb8957cb8654812e171c05b44751e641 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_16825 cb8957cb8654812e171c05b44751e641 74 SMART SM00421 9 66 4.9E-25 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_16825 cb8957cb8654812e171c05b44751e641 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 64 6.3E-24 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_16825 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 2.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_16825 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 2.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_16825 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 2.6E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 500 506 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Pfam PF00702 haloacid dehalogenase-like hydrolase 495 711 1.5E-48 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 SUPERFAMILY SSF56784 496 797 3.46E-63 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 229 799 3.3E-204 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Gene3D G3DSA:3.40.1110.10 509 629 7.7E-98 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 ProSitePatterns PS01047 Heavy-metal-associated domain. 79 108 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 SUPERFAMILY SSF81665 260 489 2.35E-11 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Gene3D G3DSA:3.30.70.100 1 72 2.1E-22 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 211 800 4.6E-187 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 269 784 3.5E-95 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Gene3D G3DSA:3.40.50.1000 479 749 7.7E-98 T 14-10-2018 IPR023214 HAD superfamily C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 697 716 3.0E-28 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 654 3.0E-28 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 346 360 3.0E-28 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 633 3.0E-28 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 498 512 3.0E-28 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 720 732 3.0E-28 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Pfam PF00122 E1-E2 ATPase 297 476 2.4E-59 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Pfam PF00403 Heavy-metal-associated domain 9 68 3.5E-16 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Pfam PF00403 Heavy-metal-associated domain 77 137 1.1E-16 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 74 138 6.2E-14 T 14-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 8 70 3.8E-9 T 14-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Gene3D G3DSA:3.30.70.100 73 148 9.6E-24 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 32 55 3.3E-15 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 212 237 3.3E-15 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 6 31 3.3E-15 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 SUPERFAMILY SSF55008 4 71 5.63E-20 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00943 Copper-transporting ATPase signature 214 233 8.6E-17 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00943 Copper-transporting ATPase signature 674 691 8.6E-17 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00943 Copper-transporting ATPase signature 286 304 8.6E-17 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00943 Copper-transporting ATPase signature 419 433 8.6E-17 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00943 Copper-transporting ATPase signature 118 138 8.6E-17 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00943 Copper-transporting ATPase signature 481 496 8.6E-17 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 PRINTS PR00943 Copper-transporting ATPase signature 266 285 8.6E-17 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 Gene3D G3DSA:2.70.150.20 289 401 3.2E-44 T 14-10-2018 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 SUPERFAMILY SSF55008 74 145 2.49E-21 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I25_20875 d1f9e739d0a2d07a6977179b11562bce 806 SUPERFAMILY SSF81653 300 396 9.42E-31 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I25_25700 1cfdccaa82c538f2c6f8db13513a8526 332 SUPERFAMILY SSF52518 10 330 4.47E-105 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_25700 1cfdccaa82c538f2c6f8db13513a8526 332 Gene3D G3DSA:3.40.50.970 2 332 1.3E-128 T 14-10-2018 C2I25_25700 1cfdccaa82c538f2c6f8db13513a8526 332 Pfam PF00676 Dehydrogenase E1 component 23 318 6.1E-95 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 C2I25_11750 c2c0264a1627642248aa3b927ab26957 449 SUPERFAMILY SSF52540 183 433 6.2E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11750 c2c0264a1627642248aa3b927ab26957 449 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 5.6E-118 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 C2I25_11750 c2c0264a1627642248aa3b927ab26957 449 Gene3D G3DSA:1.10.860.10 1 166 3.5E-64 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal C2I25_11750 c2c0264a1627642248aa3b927ab26957 449 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 442 3.7E-187 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 C2I25_11750 c2c0264a1627642248aa3b927ab26957 449 Gene3D G3DSA:3.40.50.300 167 448 2.5E-117 T 14-10-2018 C2I25_11750 c2c0264a1627642248aa3b927ab26957 449 SUPERFAMILY SSF48024 8 119 4.97E-38 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 C2I25_11750 c2c0264a1627642248aa3b927ab26957 449 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 2.9E-35 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 ProSitePatterns PS00622 LuxR-type HTH domain signature. 153 180 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 138 191 1.2E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 SMART SM00421 136 193 5.3E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 SMART SM00448 3 116 2.4E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 SUPERFAMILY SSF46894 130 199 1.02E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 6.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 6.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 6.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 SUPERFAMILY SSF52172 2 128 4.98E-27 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_21325 34af43bb644490e03e0f8477abb52607 202 Pfam PF00072 Response regulator receiver domain 6 116 4.9E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_21325 34af43bb644490e03e0f8477abb52607 202 Gene3D G3DSA:3.40.50.12740 3 199 1.2E-52 T 14-10-2018 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 SUPERFAMILY SSF52029 183 374 7.92E-86 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Gene3D G3DSA:3.50.7.10 171 377 7.8E-236 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Hamap MF_00600 60 kDa chaperonin [groL]. 1 543 42.74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 SUPERFAMILY SSF48592 5 518 2.37E-80 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Gene3D G3DSA:3.30.260.10 137 408 7.8E-236 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.3E-103 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Gene3D G3DSA:1.10.560.10 7 518 7.8E-236 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 9.7E-259 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 82 109 4.7E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 348 373 4.7E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 26 52 4.7E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 396 417 4.7E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 266 289 4.7E-73 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I25_10105 c9e652a9d8d8ef1e2c3e6687de8168a3 544 SUPERFAMILY SSF54849 136 204 1.03E-25 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 SMART SM00926 46 108 2.4E-7 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 767 784 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 Gene3D G3DSA:3.40.50.12440 47 1227 0.0 T 14-10-2018 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 8 43 1.7E-10 T 14-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 6 1226 0.0 T 14-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 SUPERFAMILY SSF53706 10 1063 0.0 T 14-10-2018 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 51 69 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 Pfam PF01568 Molydopterin dinucleotide binding domain 1079 1192 8.8E-23 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 Pfam PF00384 Molybdopterin oxidoreductase 111 823 8.0E-173 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_01055 73a989f70fa57de6954ffd13dff7f2f7 1227 SUPERFAMILY SSF50692 1070 1225 5.42E-48 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 239 2.5E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 SUPERFAMILY SSF56645 22 263 2.23E-70 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 SUPERFAMILY SSF47203 257 422 3.22E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 Gene3D G3DSA:1.20.140.10 423 594 1.2E-60 T 14-10-2018 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 32 143 4.0E-29 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 Gene3D G3DSA:1.20.140.10 252 422 8.8E-54 T 14-10-2018 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 Gene3D G3DSA:2.40.110.10 146 251 2.1E-33 T 14-10-2018 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 Gene3D G3DSA:1.10.540.10 1 145 7.2E-48 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_14060 b6a0f0568cd02b45940ce6bce3188899 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 415 1.2E-35 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I25_25280 41f7b35fc46ff661841aa062628185b3 280 SUPERFAMILY SSF109998 28 162 2.2E-14 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I25_25280 41f7b35fc46ff661841aa062628185b3 280 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 279 21.741 T 14-10-2018 IPR023059 Foldase protein PrsA GO:0003755 C2I25_25280 41f7b35fc46ff661841aa062628185b3 280 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 161 182 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 C2I25_25280 41f7b35fc46ff661841aa062628185b3 280 Gene3D G3DSA:3.10.50.40 126 221 5.7E-38 T 14-10-2018 C2I25_25280 41f7b35fc46ff661841aa062628185b3 280 SUPERFAMILY SSF54534 123 222 2.88E-33 T 14-10-2018 C2I25_25280 41f7b35fc46ff661841aa062628185b3 280 Pfam PF13616 PPIC-type PPIASE domain 132 224 2.1E-28 T 14-10-2018 C2I25_19245 678ee3ec3bcd75bf1285b36b8e5a282e 205 SUPERFAMILY SSF55469 5 203 4.58E-52 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_19245 678ee3ec3bcd75bf1285b36b8e5a282e 205 Gene3D G3DSA:3.40.109.10 1 204 7.2E-53 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_19245 678ee3ec3bcd75bf1285b36b8e5a282e 205 Pfam PF00881 Nitroreductase family 12 183 8.2E-30 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_27190 a4a2b1c11363a40148c5d13a3af6ad1e 710 Pfam PF00905 Penicillin binding protein transpeptidase domain 352 686 5.5E-67 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_27190 a4a2b1c11363a40148c5d13a3af6ad1e 710 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 306 1.2E-38 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_27190 a4a2b1c11363a40148c5d13a3af6ad1e 710 Gene3D G3DSA:3.40.710.10 321 681 6.7E-222 T 14-10-2018 C2I25_27190 a4a2b1c11363a40148c5d13a3af6ad1e 710 SUPERFAMILY SSF56601 322 692 5.83E-67 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_27190 a4a2b1c11363a40148c5d13a3af6ad1e 710 SUPERFAMILY SSF56519 57 321 1.14E-37 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_27190 a4a2b1c11363a40148c5d13a3af6ad1e 710 Gene3D G3DSA:1.10.10.1230 88 197 6.7E-222 T 14-10-2018 C2I25_27190 a4a2b1c11363a40148c5d13a3af6ad1e 710 Gene3D G3DSA:3.90.1310.30 63 575 6.7E-222 T 14-10-2018 C2I25_09200 eba056066e383d9c36eb0d028aac09b7 354 TIGRFAM TIGR00378 cax: calcium/proton exchanger 14 352 7.5E-143 T 14-10-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 C2I25_09200 eba056066e383d9c36eb0d028aac09b7 354 Pfam PF01699 Sodium/calcium exchanger protein 31 182 2.6E-19 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 C2I25_09200 eba056066e383d9c36eb0d028aac09b7 354 Pfam PF01699 Sodium/calcium exchanger protein 209 346 4.2E-19 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 C2I25_09200 eba056066e383d9c36eb0d028aac09b7 354 Gene3D G3DSA:1.20.1420.30 61 345 2.1E-23 T 14-10-2018 C2I25_09200 eba056066e383d9c36eb0d028aac09b7 354 Gene3D G3DSA:1.20.58.1130 199 241 2.1E-23 T 14-10-2018 C2I25_09200 eba056066e383d9c36eb0d028aac09b7 354 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 10 351 5.8E-118 T 14-10-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I25_23655 c8d7773934b397a65c317a095f5ea064 228 Pfam PF00072 Response regulator receiver domain 5 114 4.7E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_23655 c8d7773934b397a65c317a095f5ea064 228 Gene3D G3DSA:1.10.10.10 131 228 3.9E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23655 c8d7773934b397a65c317a095f5ea064 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 1.3E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_23655 c8d7773934b397a65c317a095f5ea064 228 SUPERFAMILY SSF46894 128 228 1.33E-29 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_23655 c8d7773934b397a65c317a095f5ea064 228 Gene3D G3DSA:3.40.50.2300 1 130 8.2E-42 T 14-10-2018 C2I25_23655 c8d7773934b397a65c317a095f5ea064 228 SUPERFAMILY SSF52172 2 128 3.13E-44 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_23655 c8d7773934b397a65c317a095f5ea064 228 SMART SM00862 152 228 3.4E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_23655 c8d7773934b397a65c317a095f5ea064 228 SMART SM00448 3 113 1.3E-45 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_07170 94fe6f93bf8289b5286218ba4036c849 119 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_07170 94fe6f93bf8289b5286218ba4036c849 119 SMART SM00422 2 70 9.9E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_07170 94fe6f93bf8289b5286218ba4036c849 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.0E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_07170 94fe6f93bf8289b5286218ba4036c849 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 5.0E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_07170 94fe6f93bf8289b5286218ba4036c849 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 5.0E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_07170 94fe6f93bf8289b5286218ba4036c849 119 Pfam PF13411 MerR HTH family regulatory protein 2 67 1.5E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_07170 94fe6f93bf8289b5286218ba4036c849 119 SUPERFAMILY SSF46955 2 114 1.32E-31 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_07170 94fe6f93bf8289b5286218ba4036c849 119 Gene3D G3DSA:1.10.1660.10 1 119 1.5E-32 T 14-10-2018 C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 Pfam PF00005 ABC transporter 21 189 4.1E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 Pfam PF00005 ABC transporter 338 464 4.7E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 Pfam PF12848 ABC transporter 228 302 4.0E-20 T 14-10-2018 IPR032781 ABC-transporter extension domain C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 SUPERFAMILY SSF52540 309 507 1.99E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 Gene3D G3DSA:3.40.50.300 285 514 2.5E-50 T 14-10-2018 C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 Gene3D G3DSA:3.40.50.300 2 284 7.5E-60 T 14-10-2018 C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 SUPERFAMILY SSF52540 3 254 7.24E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 SMART SM00382 28 233 1.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 SMART SM00382 345 509 5.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_09385 00b9e4f676f817c322f526bbeaee1a69 514 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 SUPERFAMILY SSF52768 4 293 1.04E-92 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 Gene3D G3DSA:3.40.800.10 2 297 8.0E-115 T 14-10-2018 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 PRINTS PR00116 Arginase signature 254 268 1.9E-40 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 PRINTS PR00116 Arginase signature 117 144 1.9E-40 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 PRINTS PR00116 Arginase signature 94 109 1.9E-40 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 PRINTS PR00116 Arginase signature 219 248 1.9E-40 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 PRINTS PR00116 Arginase signature 171 189 1.9E-40 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 TIGRFAM TIGR01229 rocF_arginase: arginase 6 296 9.9E-106 T 14-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 PIRSF PIRSF036979 1 294 6.6E-40 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 Pfam PF00491 Arginase family 4 292 3.9E-80 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_10690 bf2e5c5be57124c8ceab7a82f52cb22a 297 ProSitePatterns PS01053 Arginase family signature. 222 243 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 C2I25_06710 13001c85d99b4965b7be438ef87c540e 261 SUPERFAMILY SSF46785 2 97 2.89E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_06710 13001c85d99b4965b7be438ef87c540e 261 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 76 2.2E-23 T 14-10-2018 IPR002831 Transcription regulator TrmB, N-terminal C2I25_06710 13001c85d99b4965b7be438ef87c540e 261 Pfam PF11495 Archaeal transcriptional regulator TrmB 111 228 1.8E-5 T 14-10-2018 IPR021586 Transcription regulator TrmB, C-terminal C2I25_06710 13001c85d99b4965b7be438ef87c540e 261 Gene3D G3DSA:1.10.10.10 2 102 1.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 2.3E-121 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 Gene3D G3DSA:3.40.50.720 4 260 3.4E-76 T 14-10-2018 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 1.3E-62 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 1.3E-62 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 1.3E-62 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 1.3E-62 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 1.3E-62 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 1.3E-62 T 14-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 SUPERFAMILY SSF51735 7 259 1.37E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.2E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.2E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.2E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28170 b0aade989f927aa75d0178503f0f388a 261 Pfam PF00106 short chain dehydrogenase 9 201 1.2E-59 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 Pfam PF01872 RibD C-terminal domain 148 354 1.2E-55 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 146 356 2.3E-69 T 14-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 356 4.7E-125 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 Gene3D G3DSA:3.40.430.10 137 363 1.6E-78 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 Gene3D G3DSA:3.40.140.10 1 136 1.8E-45 T 14-10-2018 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 PIRSF PIRSF006769 1 362 1.8E-134 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 SUPERFAMILY SSF53927 4 143 5.22E-46 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 SUPERFAMILY SSF53597 145 359 2.66E-63 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I25_22855 ab5a5b3ac3b85e17b0f5d929e4bbfafe 367 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 9.8E-22 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I25_27960 4332965e7c698974997fcb55cf2d5389 169 Gene3D G3DSA:3.40.630.30 2 162 4.1E-37 T 14-10-2018 C2I25_27960 4332965e7c698974997fcb55cf2d5389 169 Pfam PF00583 Acetyltransferase (GNAT) family 44 135 9.3E-20 T 14-10-2018 IPR000182 GNAT domain C2I25_27960 4332965e7c698974997fcb55cf2d5389 169 SUPERFAMILY SSF55729 3 160 2.53E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_22105 1cb59c69b7b8f1494d98c0961f375a79 231 Pfam PF00072 Response regulator receiver domain 5 114 8.8E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_22105 1cb59c69b7b8f1494d98c0961f375a79 231 SUPERFAMILY SSF52172 4 119 4.7E-39 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_22105 1cb59c69b7b8f1494d98c0961f375a79 231 SMART SM00862 152 229 6.6E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_22105 1cb59c69b7b8f1494d98c0961f375a79 231 SMART SM00448 3 113 8.1E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_22105 1cb59c69b7b8f1494d98c0961f375a79 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 1.8E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_22105 1cb59c69b7b8f1494d98c0961f375a79 231 Gene3D G3DSA:3.40.50.2300 1 122 5.8E-36 T 14-10-2018 C2I25_22105 1cb59c69b7b8f1494d98c0961f375a79 231 Gene3D G3DSA:1.10.10.10 127 231 1.3E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22105 1cb59c69b7b8f1494d98c0961f375a79 231 SUPERFAMILY SSF46894 129 229 9.64E-29 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 Gene3D G3DSA:3.40.1110.10 333 463 2.7E-44 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 Gene3D G3DSA:2.70.150.20 123 228 5.5E-27 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 SUPERFAMILY SSF81653 128 224 1.96E-22 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 25 693 0.0 T 14-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 Gene3D G3DSA:3.40.50.1000 464 582 9.9E-28 T 14-10-2018 IPR023214 HAD superfamily C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 SUPERFAMILY SSF81665 52 678 4.05E-13 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 SUPERFAMILY SSF56784 310 576 5.07E-41 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 324 330 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 469 5.5E-26 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 568 5.5E-26 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 5.5E-26 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 490 5.5E-26 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 322 336 5.5E-26 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 171 185 5.5E-26 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 Pfam PF00122 E1-E2 ATPase 126 301 9.2E-35 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 Pfam PF00702 haloacid dehalogenase-like hydrolase 318 547 1.4E-36 T 14-10-2018 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 29 697 39.65 T 14-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 385 618 1.3E-48 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_07660 7584e726c7c1f8cafd3d495b7aea735b 697 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 347 4.1E-32 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 Gene3D G3DSA:3.30.565.10 378 528 4.2E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 324 368 1.2E-8 T 14-10-2018 IPR039506 SpoOB, alpha-helical domain C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 Pfam PF17203 Single cache domain 3 40 170 8.3E-29 T 14-10-2018 IPR033463 Single cache domain 3 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 SUPERFAMILY SSF55874 388 530 1.44E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 428 532 1.2E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 SMART SM00387 422 533 6.2E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 SUPERFAMILY SSF55785 210 311 1.43E-8 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 Gene3D G3DSA:3.30.450.20 202 314 2.3E-21 T 14-10-2018 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 Pfam PF00989 PAS fold 219 290 5.6E-7 T 14-10-2018 IPR013767 PAS fold GO:0006355 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 Gene3D G3DSA:3.30.450.20 33 167 3.0E-49 T 14-10-2018 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 SUPERFAMILY SSF103190 39 169 2.51E-40 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 4.7E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 477 4.7E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 530 4.7E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 491 4.7E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 SMART SM00091 216 283 0.0018 T 14-10-2018 IPR000014 PAS domain C2I25_08695 2596b45788ac6bdd2b9c35fde7f50929 535 SUPERFAMILY SSF55890 325 407 2.09E-9 T 14-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I25_12525 34452d23655a00813c65988d30454050 358 Gene3D G3DSA:3.30.70.1660 113 343 6.0E-96 T 14-10-2018 C2I25_12525 34452d23655a00813c65988d30454050 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 4 358 40.658 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 C2I25_12525 34452d23655a00813c65988d30454050 358 Pfam PF03462 PCRF domain 12 205 1.1E-73 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 C2I25_12525 34452d23655a00813c65988d30454050 358 Gene3D G3DSA:3.30.160.20 212 298 6.0E-96 T 14-10-2018 C2I25_12525 34452d23655a00813c65988d30454050 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 356 3.6E-171 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 C2I25_12525 34452d23655a00813c65988d30454050 358 SUPERFAMILY SSF75620 11 354 2.62E-133 T 14-10-2018 C2I25_12525 34452d23655a00813c65988d30454050 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 C2I25_12525 34452d23655a00813c65988d30454050 358 Gene3D G3DSA:1.20.58.410 1 105 1.1E-7 T 14-10-2018 C2I25_12525 34452d23655a00813c65988d30454050 358 SMART SM00937 66 180 3.8E-65 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 C2I25_12525 34452d23655a00813c65988d30454050 358 Pfam PF00472 RF-1 domain 213 322 2.9E-40 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 C2I25_12815 37eb9418698513335ac8f47a99191671 293 SUPERFAMILY SSF53448 4 278 1.04E-69 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_12815 37eb9418698513335ac8f47a99191671 293 Gene3D G3DSA:3.90.550.10 1 290 7.1E-96 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_12815 37eb9418698513335ac8f47a99191671 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 1.3E-120 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 C2I25_12815 37eb9418698513335ac8f47a99191671 293 Pfam PF00483 Nucleotidyl transferase 6 260 9.3E-35 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_26085 474acc600a52f6a0c6e380eadb9cf154 283 Pfam PF01734 Patatin-like phospholipase 6 170 3.1E-19 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I25_26085 474acc600a52f6a0c6e380eadb9cf154 283 Gene3D G3DSA:3.40.1090.10 1 91 4.2E-14 T 14-10-2018 C2I25_26085 474acc600a52f6a0c6e380eadb9cf154 283 SUPERFAMILY SSF52151 2 274 1.73E-46 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 SUPERFAMILY SSF63380 676 899 2.43E-63 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Pfam PF00067 Cytochrome P450 17 449 2.5E-86 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Gene3D G3DSA:1.10.630.10 4 472 1.9E-169 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Gene3D G3DSA:3.40.50.360 494 644 4.9E-45 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 SUPERFAMILY SSF52343 903 1062 9.95E-46 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Pfam PF00258 Flavodoxin 498 630 6.3E-27 T 14-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 398 407 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 SUPERFAMILY SSF52218 492 648 9.43E-42 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Gene3D G3DSA:3.40.50.80 904 1064 1.5E-56 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 878 887 1.8E-30 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 944 953 1.8E-30 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1011 1019 1.8E-30 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 843 850 1.8E-30 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 988 1004 1.8E-30 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 957 968 1.8E-30 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 709 719 1.8E-30 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 915 934 1.8E-30 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00369 Flavodoxin signature 575 585 5.1E-9 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00369 Flavodoxin signature 600 619 5.1E-9 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PRINTS PR00369 Flavodoxin signature 497 510 5.1E-9 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Gene3D G3DSA:1.20.990.10 719 841 1.4E-68 T 14-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 SUPERFAMILY SSF48264 5 456 1.96E-109 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Pfam PF00175 Oxidoreductase NAD-binding domain 916 1026 8.3E-15 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 PIRSF PIRSF000209 2 1065 0.0 T 14-10-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Pfam PF00667 FAD binding domain 677 883 5.0E-40 T 14-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 C2I25_23625 edad27e8bfbf8d3e53e1af4325d6790d 1065 Gene3D G3DSA:2.40.30.10 684 893 1.4E-68 T 14-10-2018 C2I25_19475 a708433744435543de33687223597245 185 Gene3D G3DSA:1.10.10.10 1 103 3.7E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19475 a708433744435543de33687223597245 185 Pfam PF03551 Transcriptional regulator PadR-like family 7 81 2.8E-9 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_19475 a708433744435543de33687223597245 185 SUPERFAMILY SSF46785 3 171 1.43E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 4.0E-127 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 Gene3D G3DSA:3.30.1360.10 16 221 1.4E-90 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 6.0E-26 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 SUPERFAMILY SSF55257 5 230 7.06E-33 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 Gene3D G3DSA:2.170.120.12 50 170 1.4E-90 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 5.8E-24 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 SMART SM00662 20 227 1.9E-107 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 6.7E-25 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.78 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 SUPERFAMILY SSF47789 247 313 9.29E-25 T 14-10-2018 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 Gene3D G3DSA:1.10.150.20 237 314 1.7E-34 T 14-10-2018 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 SUPERFAMILY SSF56553 50 171 1.31E-44 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_10835 da80a6f8af08c7570750a95ef56c673e 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 2.4E-29 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 Gene3D G3DSA:1.10.287.950 337 643 1.8E-69 T 14-10-2018 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 Gene3D G3DSA:3.30.450.20 47 255 3.6E-31 T 14-10-2018 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 Gene3D G3DSA:3.30.450.20 56 167 3.6E-31 T 14-10-2018 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 SMART SM00319 17 135 6.6E-4 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 SMART SM00283 368 643 2.5E-82 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 SMART SM00304 287 339 8.3E-17 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 SUPERFAMILY SSF58104 307 643 4.19E-75 T 14-10-2018 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 Pfam PF02743 Cache domain 30 249 8.0E-26 T 14-10-2018 IPR033479 Double Cache domain 1 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 Pfam PF00672 HAMP domain 287 335 5.2E-16 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 Gene3D G3DSA:1.10.8.500 287 336 2.3E-9 T 14-10-2018 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 418 594 4.6E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_22010 e1438b256e6b5cd8fd99d7d880da650a 644 SUPERFAMILY SSF103190 79 174 2.47E-7 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 Pfam PF03466 LysR substrate binding domain 90 289 4.7E-39 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 SUPERFAMILY SSF46785 5 111 2.53E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 Gene3D G3DSA:3.40.190.290 92 295 6.1E-41 T 14-10-2018 C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 Gene3D G3DSA:1.10.10.10 1 91 8.4E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 SUPERFAMILY SSF53850 90 293 5.98E-38 T 14-10-2018 C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02930 c56aa9bac01040f513fe9f656e80fc46 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.6E-12 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Pfam PF03144 Elongation factor Tu domain 2 224 294 3.3E-12 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Pfam PF00009 Elongation factor Tu GTP binding domain 7 200 3.4E-57 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 SMART SM00838 400 488 9.8E-5 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 SUPERFAMILY SSF52540 3 211 3.56E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 54 62 2.6E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.6E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.6E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 10 23 2.6E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.6E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:3.30.70.240 394 487 2.1E-128 T 14-10-2018 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:3.40.50.300 5 203 1.3E-66 T 14-10-2018 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:2.40.30.10 204 304 1.2E-33 T 14-10-2018 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Pfam PF00679 Elongation factor G C-terminus 402 482 2.5E-25 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:3.30.70.870 311 595 2.1E-128 T 14-10-2018 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 155 1.3E-22 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Pfam PF14492 Elongation Factor G, domain II 333 382 3.8E-7 T 14-10-2018 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 SUPERFAMILY SSF54980 307 392 4.32E-15 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:2.40.50.250 488 604 2.1E-128 T 14-10-2018 C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 SUPERFAMILY SSF50447 155 304 1.35E-31 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 SUPERFAMILY SSF54980 403 518 3.36E-29 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_19710 940b845aa94eae1e0abf41a9788fab04 614 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 604 4.6E-290 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 C2I25_02815 586a3c64d0d555f336287d6e3335fc52 321 Pfam PF00892 EamA-like transporter family 161 300 1.2E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_02815 586a3c64d0d555f336287d6e3335fc52 321 Pfam PF00892 EamA-like transporter family 7 148 1.0E-23 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_02815 586a3c64d0d555f336287d6e3335fc52 321 SUPERFAMILY SSF103481 44 150 1.28E-9 T 14-10-2018 C2I25_02815 586a3c64d0d555f336287d6e3335fc52 321 SUPERFAMILY SSF103481 214 302 1.44E-9 T 14-10-2018 C2I25_17990 1c6ff254e719ff814a20f049066427eb 370 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 79 294 3.0E-43 T 14-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 C2I25_17990 1c6ff254e719ff814a20f049066427eb 370 Gene3D G3DSA:3.40.50.12710 6 368 1.1E-94 T 14-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 C2I25_17990 1c6ff254e719ff814a20f049066427eb 370 SUPERFAMILY SSF53335 17 361 2.57E-80 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_26955 42006a38cef87c6bc6df3ab6c6bdae2e 238 Gene3D G3DSA:3.40.50.720 1 237 3.0E-43 T 14-10-2018 C2I25_26955 42006a38cef87c6bc6df3ab6c6bdae2e 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 236 6.1E-32 T 14-10-2018 C2I25_26955 42006a38cef87c6bc6df3ab6c6bdae2e 238 SUPERFAMILY SSF51735 5 237 3.46E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_26955 42006a38cef87c6bc6df3ab6c6bdae2e 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_26955 42006a38cef87c6bc6df3ab6c6bdae2e 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_26955 42006a38cef87c6bc6df3ab6c6bdae2e 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_26955 42006a38cef87c6bc6df3ab6c6bdae2e 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_26955 42006a38cef87c6bc6df3ab6c6bdae2e 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.3E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_24255 db5a5ba62dc796742ba473dfa1ca42fa 717 Gene3D G3DSA:3.40.710.10 326 687 3.0E-221 T 14-10-2018 C2I25_24255 db5a5ba62dc796742ba473dfa1ca42fa 717 SUPERFAMILY SSF56519 62 326 2.49E-37 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_24255 db5a5ba62dc796742ba473dfa1ca42fa 717 SUPERFAMILY SSF56601 328 699 5.23E-65 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_24255 db5a5ba62dc796742ba473dfa1ca42fa 717 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 311 2.2E-37 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_24255 db5a5ba62dc796742ba473dfa1ca42fa 717 Gene3D G3DSA:1.10.10.1230 93 202 3.0E-221 T 14-10-2018 C2I25_24255 db5a5ba62dc796742ba473dfa1ca42fa 717 Pfam PF00905 Penicillin binding protein transpeptidase domain 357 693 1.1E-69 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_24255 db5a5ba62dc796742ba473dfa1ca42fa 717 Gene3D G3DSA:3.90.1310.30 68 580 3.0E-221 T 14-10-2018 C2I25_23670 56ed72e50a4ba963a6a8ed6732f43c5d 609 Pfam PF02687 FtsX-like permease family 84 179 1.7E-9 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_23670 56ed72e50a4ba963a6a8ed6732f43c5d 609 PIRSF PIRSF018968 414 607 5.3E-19 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_23670 56ed72e50a4ba963a6a8ed6732f43c5d 609 PIRSF PIRSF018968 1 411 5.6E-34 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_16070 ba7701704a53a592a1b8b9f3ed1f74ae 143 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 136 1.7E-8 T 14-10-2018 IPR028973 PhnB-like C2I25_16070 ba7701704a53a592a1b8b9f3ed1f74ae 143 Gene3D G3DSA:3.10.180.10 9 143 2.9E-44 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_16070 ba7701704a53a592a1b8b9f3ed1f74ae 143 SUPERFAMILY SSF54593 2 137 1.94E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_00085 f0013ed7b79b81de89373fbc2932108f 178 SUPERFAMILY SSF52218 1 160 1.27E-37 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_00085 f0013ed7b79b81de89373fbc2932108f 178 Pfam PF03358 NADPH-dependent FMN reductase 1 136 7.8E-32 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 C2I25_00085 f0013ed7b79b81de89373fbc2932108f 178 Gene3D G3DSA:3.40.50.360 1 171 3.8E-42 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 SUPERFAMILY SSF56655 5 263 8.9E-75 T 14-10-2018 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 1.2E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 1.2E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 1.2E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 1.2E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 1.2E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 1.2E-35 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 Pfam PF00459 Inositol monophosphatase family 8 255 7.2E-62 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 Gene3D G3DSA:3.40.190.80 146 267 1.0E-31 T 14-10-2018 C2I25_19700 615ddbba6d50775e5d6ee025306f26eb 267 Gene3D G3DSA:3.30.540.10 1 144 6.3E-45 T 14-10-2018 C2I25_21115 41ae673960c3a13329ffac665254af7a 251 Pfam PF01925 Sulfite exporter TauE/SafE 4 245 4.5E-39 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I25_20630 85e7cb76631d35058b13bb7a4c5a707f 264 SUPERFAMILY SSF56300 1 256 1.33E-90 T 14-10-2018 C2I25_20630 85e7cb76631d35058b13bb7a4c5a707f 264 PIRSF PIRSF004789 1 263 4.3E-102 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like C2I25_20630 85e7cb76631d35058b13bb7a4c5a707f 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 1.5E-114 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like C2I25_20630 85e7cb76631d35058b13bb7a4c5a707f 264 Pfam PF13277 YmdB-like protein 4 254 3.2E-109 T 14-10-2018 IPR005235 Metallophosphoesterase, YmdB-like C2I25_20630 85e7cb76631d35058b13bb7a4c5a707f 264 Gene3D G3DSA:3.60.21.10 1 264 1.6E-115 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 Gene3D G3DSA:3.90.1150.10 25 385 1.2E-142 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 Pfam PF00155 Aminotransferase class I and II 31 385 2.3E-82 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 2.2E-17 T 14-10-2018 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 2.2E-17 T 14-10-2018 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 2.2E-17 T 14-10-2018 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 2.2E-17 T 14-10-2018 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 2.2E-17 T 14-10-2018 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 Gene3D G3DSA:3.40.640.10 62 284 1.2E-142 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 C2I25_03665 01d307ee276cac0dc0765cdfc72800ca 395 SUPERFAMILY SSF53383 1 390 8.38E-120 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 SMART SM00889 423 538 2.9E-7 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Pfam PF00679 Elongation factor G C-terminus 541 618 7.2E-9 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Pfam PF14492 Elongation Factor G, domain II 347 420 7.3E-9 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Gene3D G3DSA:3.30.70.240 544 614 2.3E-19 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Gene3D G3DSA:3.30.70.870 349 421 7.4E-9 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Pfam PF00009 Elongation factor Tu GTP binding domain 3 241 2.0E-61 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 SUPERFAMILY SSF54211 443 538 4.17E-14 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Gene3D G3DSA:3.40.50.300 1 250 2.4E-79 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Gene3D G3DSA:2.40.30.10 251 348 1.6E-12 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 270 296 4.3E-35 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 461 475 4.3E-35 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 510 527 4.3E-35 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 4.3E-35 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 216 238 4.3E-35 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 476 498 4.3E-35 T 14-10-2018 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 153 3.4E-35 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 SUPERFAMILY SSF52540 4 242 1.73E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 SUPERFAMILY SSF54980 541 619 3.41E-8 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Pfam PF03764 Elongation factor G, domain IV 445 538 1.0E-12 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 Gene3D G3DSA:3.30.230.10 448 618 2.3E-19 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.0E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 SUPERFAMILY SSF54980 347 424 1.19E-12 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_24410 2b40054c036bcea3d8172c43d501cc3a 647 SUPERFAMILY SSF50447 226 339 3.53E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_03780 4a52efc71da1ed7933fb4fd602aff2ce 255 SUPERFAMILY SSF46626 141 252 9.03E-13 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I25_03780 4a52efc71da1ed7933fb4fd602aff2ce 255 Gene3D G3DSA:1.10.760.10 182 253 3.1E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I25_03780 4a52efc71da1ed7933fb4fd602aff2ce 255 SUPERFAMILY SSF81648 21 156 7.46E-30 T 14-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 C2I25_03780 4a52efc71da1ed7933fb4fd602aff2ce 255 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 249 1.6E-12 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_03780 4a52efc71da1ed7933fb4fd602aff2ce 255 PIRSF PIRSF036636 1 255 5.2E-154 T 14-10-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 C2I25_03780 4a52efc71da1ed7933fb4fd602aff2ce 255 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 81 160 1.8E-9 T 14-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 C2I25_03780 4a52efc71da1ed7933fb4fd602aff2ce 255 Gene3D G3DSA:1.20.810.10 14 174 2.8E-25 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 ProSitePatterns PS00761 Signal peptidases I signature 3. 130 143 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 166 2.0E-50 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 125 144 1.6E-17 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 1.6E-17 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 87 1.6E-17 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 Gene3D G3DSA:2.10.109.10 54 173 9.2E-36 T 14-10-2018 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 Pfam PF00717 Peptidase S24-like 30 99 9.9E-20 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 ProSitePatterns PS00760 Signal peptidases I lysine active site. 77 89 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I25_24260 db2b50d3c5b4fce7cfdb5fa2fd574301 173 SUPERFAMILY SSF51306 25 172 4.8E-49 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I25_05475 1c455ba931e4e8638b972eb96581b800 311 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 278 1.2E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_05475 1c455ba931e4e8638b972eb96581b800 311 Gene3D G3DSA:3.40.50.300 6 310 5.6E-95 T 14-10-2018 C2I25_05475 1c455ba931e4e8638b972eb96581b800 311 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_05475 1c455ba931e4e8638b972eb96581b800 311 SMART SM00382 37 231 4.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_05475 1c455ba931e4e8638b972eb96581b800 311 SUPERFAMILY SSF52540 8 253 2.66E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05475 1c455ba931e4e8638b972eb96581b800 311 Pfam PF00005 ABC transporter 29 181 4.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_07215 bffa62ba3ca32975ba7dba538a0e5e75 454 SUPERFAMILY SSF55604 7 82 1.44E-19 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_07215 bffa62ba3ca32975ba7dba538a0e5e75 454 Pfam PF00367 phosphotransferase system, EIIB 9 42 2.9E-15 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_07215 bffa62ba3ca32975ba7dba538a0e5e75 454 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_07215 bffa62ba3ca32975ba7dba538a0e5e75 454 Gene3D G3DSA:3.30.1360.60 1 78 4.7E-23 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_07215 bffa62ba3ca32975ba7dba538a0e5e75 454 Pfam PF02378 Phosphotransferase system, EIIC 121 389 1.7E-34 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 SMART SM00491 766 900 6.3E-32 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 Gene3D G3DSA:3.30.420.10 1 172 6.4E-51 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 SUPERFAMILY SSF53098 4 273 1.45E-55 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_03680 6d5f66270a52b79473337f43f7933080 934 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 168 7.5E-28 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 Gene3D G3DSA:3.40.50.300 718 923 2.5E-44 T 14-10-2018 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 SUPERFAMILY SSF52540 273 894 2.19E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03680 6d5f66270a52b79473337f43f7933080 934 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 4 929 2.0E-266 T 14-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 Pfam PF04851 Type III restriction enzyme, res subunit 257 481 5.5E-6 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 Pfam PF00929 Exonuclease 6 163 1.2E-31 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_03680 6d5f66270a52b79473337f43f7933080 934 SMART SM00479 4 172 1.2E-47 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_03680 6d5f66270a52b79473337f43f7933080 934 Gene3D G3DSA:3.40.50.300 257 520 5.1E-45 T 14-10-2018 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 Hamap MF_02206 3'-5' exonuclease DinG [dinG]. 1 932 27.943 T 14-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 C2I25_03680 6d5f66270a52b79473337f43f7933080 934 SMART SM00487 255 523 0.0057 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_03680 6d5f66270a52b79473337f43f7933080 934 Pfam PF13307 Helicase C-terminal domain 748 913 2.2E-41 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 C2I25_19085 fed432ba7ac59b7b7ecea113d37f3342 116 SUPERFAMILY SSF52091 3 111 3.53E-31 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_19085 fed432ba7ac59b7b7ecea113d37f3342 116 Pfam PF01740 STAS domain 5 107 8.0E-23 T 14-10-2018 IPR002645 STAS domain C2I25_19085 fed432ba7ac59b7b7ecea113d37f3342 116 Gene3D G3DSA:3.30.750.24 2 116 2.0E-33 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_19085 fed432ba7ac59b7b7ecea113d37f3342 116 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 110 8.4E-46 T 14-10-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 C2I25_19085 fed432ba7ac59b7b7ecea113d37f3342 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 106 1.4E-36 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 26 108 4.6E-21 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 15 617 7.7E-259 T 14-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 Gene3D G3DSA:2.60.40.1180 515 619 4.9E-35 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 Gene3D G3DSA:3.20.20.80 125 514 1.4E-147 T 14-10-2018 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 SUPERFAMILY SSF51445 81 508 2.54E-106 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 SUPERFAMILY SSF51011 515 619 6.48E-32 T 14-10-2018 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 1 619 40.71 T 14-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 520 618 4.8E-22 T 14-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 PIRSF PIRSF000463 3 629 3.1E-260 T 14-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 Pfam PF00128 Alpha amylase, catalytic domain 175 250 1.3E-8 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 Pfam PF00128 Alpha amylase, catalytic domain 278 472 4.4E-5 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 SMART SM00642 152 504 1.3E-7 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_14825 844ce44641570d22f0ab0db1d1c04fac 645 Gene3D G3DSA:2.60.40.10 3 122 2.7E-42 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_22680 50ff33a659df97583b9ca86363af2bba 276 Gene3D G3DSA:3.90.1200.10 50 214 3.0E-12 T 14-10-2018 C2I25_22680 50ff33a659df97583b9ca86363af2bba 276 Pfam PF01636 Phosphotransferase enzyme family 23 212 3.6E-8 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_22680 50ff33a659df97583b9ca86363af2bba 276 SUPERFAMILY SSF56112 1 272 8.16E-25 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_22680 50ff33a659df97583b9ca86363af2bba 276 Gene3D G3DSA:3.30.200.150 22 90 3.0E-12 T 14-10-2018 C2I25_27715 4cb5e7d8d21a6cd14ff4aaae84ec5f44 384 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 380 35.833 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 C2I25_27715 4cb5e7d8d21a6cd14ff4aaae84ec5f44 384 Gene3D G3DSA:3.30.420.40 149 340 1.7E-126 T 14-10-2018 C2I25_27715 4cb5e7d8d21a6cd14ff4aaae84ec5f44 384 Gene3D G3DSA:3.30.420.40 8 375 1.7E-126 T 14-10-2018 C2I25_27715 4cb5e7d8d21a6cd14ff4aaae84ec5f44 384 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 2 378 4.3E-95 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 C2I25_27715 4cb5e7d8d21a6cd14ff4aaae84ec5f44 384 SUPERFAMILY SSF53067 1 339 6.47E-17 T 14-10-2018 C2I25_21785 a62aacbc0e6a76ae318fd4b8b4c03a3a 313 TIGRFAM TIGR00688 rarD: protein RarD 9 266 2.7E-80 T 14-10-2018 IPR004626 RarD protein GO:0005887 C2I25_21785 a62aacbc0e6a76ae318fd4b8b4c03a3a 313 SUPERFAMILY SSF103481 46 151 9.81E-11 T 14-10-2018 C2I25_21785 a62aacbc0e6a76ae318fd4b8b4c03a3a 313 Pfam PF00892 EamA-like transporter family 10 150 2.9E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_21785 a62aacbc0e6a76ae318fd4b8b4c03a3a 313 SUPERFAMILY SSF103481 214 291 7.85E-7 T 14-10-2018 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 Pfam PF00248 Aldo/keto reductase family 30 265 3.9E-50 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 PRINTS PR00069 Aldo-keto reductase signature 99 117 1.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 PRINTS PR00069 Aldo-keto reductase signature 163 192 1.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 PRINTS PR00069 Aldo-keto reductase signature 200 224 1.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 PRINTS PR00069 Aldo-keto reductase signature 129 146 1.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 Gene3D G3DSA:3.20.20.100 1 279 2.6E-126 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 PIRSF PIRSF000097 1 124 2.2E-41 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 PIRSF PIRSF000097 119 276 3.1E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 233 248 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 SUPERFAMILY SSF51430 5 274 6.42E-95 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_22830 01d21633128f24afddf944cc00bb1b74 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_00985 40695e777c3ab3e452bb70e24eec07c8 157 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 5 152 1.1E-29 T 14-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_00985 40695e777c3ab3e452bb70e24eec07c8 157 Pfam PF13241 Putative NAD(P)-binding 7 111 4.8E-24 T 14-10-2018 C2I25_00985 40695e777c3ab3e452bb70e24eec07c8 157 SUPERFAMILY SSF75615 107 147 1.96E-6 T 14-10-2018 C2I25_00985 40695e777c3ab3e452bb70e24eec07c8 157 SUPERFAMILY SSF51735 3 102 3.94E-20 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_00985 40695e777c3ab3e452bb70e24eec07c8 157 Gene3D G3DSA:3.40.50.720 4 127 1.8E-35 T 14-10-2018 C2I25_10425 7d291b0f0f528dd9c42f9d2f7d5ac8c4 254 SUPERFAMILY SSF51556 3 251 2.42E-56 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_10425 7d291b0f0f528dd9c42f9d2f7d5ac8c4 254 Pfam PF01026 TatD related DNase 4 251 3.0E-51 T 14-10-2018 IPR001130 TatD family GO:0016788 C2I25_10425 7d291b0f0f528dd9c42f9d2f7d5ac8c4 254 PIRSF PIRSF005902 1 254 2.4E-62 T 14-10-2018 IPR001130 TatD family GO:0016788 C2I25_10425 7d291b0f0f528dd9c42f9d2f7d5ac8c4 254 Gene3D G3DSA:3.20.20.140 1 253 7.0E-64 T 14-10-2018 C2I25_05940 16093d5368fb8708a25b4cd0f6c616db 351 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 167 175 - T 14-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 C2I25_05940 16093d5368fb8708a25b4cd0f6c616db 351 Gene3D G3DSA:3.40.190.10 49 317 2.7E-140 T 14-10-2018 C2I25_05940 16093d5368fb8708a25b4cd0f6c616db 351 SUPERFAMILY SSF53850 44 350 1.06E-92 T 14-10-2018 C2I25_05940 16093d5368fb8708a25b4cd0f6c616db 351 Pfam PF13531 Bacterial extracellular solute-binding protein 57 302 2.2E-44 T 14-10-2018 C2I25_05940 16093d5368fb8708a25b4cd0f6c616db 351 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 42 348 4.8E-153 T 14-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 C2I25_05940 16093d5368fb8708a25b4cd0f6c616db 351 Gene3D G3DSA:3.40.190.10 136 347 2.7E-140 T 14-10-2018 C2I25_12070 2abc9cd1ab6a14a863cf45fd7b1031fd 369 Gene3D G3DSA:3.40.50.2000 167 348 5.7E-67 T 14-10-2018 C2I25_12070 2abc9cd1ab6a14a863cf45fd7b1031fd 369 SUPERFAMILY SSF53756 40 366 8.48E-72 T 14-10-2018 C2I25_12070 2abc9cd1ab6a14a863cf45fd7b1031fd 369 Pfam PF00534 Glycosyl transferases group 1 180 329 7.9E-30 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 C2I25_12070 2abc9cd1ab6a14a863cf45fd7b1031fd 369 Pfam PF13439 Glycosyltransferase Family 4 13 169 8.0E-20 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I25_12070 2abc9cd1ab6a14a863cf45fd7b1031fd 369 Gene3D G3DSA:3.40.50.2000 44 358 5.7E-67 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 Gene3D G3DSA:3.30.390.30 348 468 6.5E-43 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 Gene3D G3DSA:3.50.50.60 152 273 3.0E-127 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 2.9E-75 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 Gene3D G3DSA:3.50.50.60 13 335 3.0E-127 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 7.3E-43 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 7.3E-43 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 7.3E-43 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 7.3E-43 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 7.3E-43 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 SUPERFAMILY SSF55424 346 468 9.28E-40 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 468 1.7E-176 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 7.5E-35 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PIRSF PIRSF000350 3 459 6.8E-100 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 6.5E-76 T 14-10-2018 C2I25_19645 f8e3197af591ccb7be8c4c6bb5f8d27a 470 SUPERFAMILY SSF51905 8 340 2.24E-67 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_01810 8da94c360a68aa72d9692c328c896933 223 Pfam PF01596 O-methyltransferase 31 205 6.0E-43 T 14-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 C2I25_01810 8da94c360a68aa72d9692c328c896933 223 SUPERFAMILY SSF53335 33 222 1.38E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_01810 8da94c360a68aa72d9692c328c896933 223 Gene3D G3DSA:3.40.50.150 1 223 3.7E-80 T 14-10-2018 C2I25_24895 66686a73aad323fc53f4d01587770f4d 181 SUPERFAMILY SSF55729 5 171 1.57E-35 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24895 66686a73aad323fc53f4d01587770f4d 181 Gene3D G3DSA:3.40.630.30 1 179 2.0E-38 T 14-10-2018 C2I25_24895 66686a73aad323fc53f4d01587770f4d 181 Pfam PF13302 Acetyltransferase (GNAT) domain 7 145 1.1E-22 T 14-10-2018 IPR000182 GNAT domain C2I25_12495 4c0a6eaf627705fd638995a447a6ab9d 429 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 42.428 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_12495 4c0a6eaf627705fd638995a447a6ab9d 429 Gene3D G3DSA:3.65.10.10 21 229 1.0E-161 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I25_12495 4c0a6eaf627705fd638995a447a6ab9d 429 SUPERFAMILY SSF55205 1 416 2.29E-134 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 C2I25_12495 4c0a6eaf627705fd638995a447a6ab9d 429 Gene3D G3DSA:3.65.10.10 6 413 1.0E-161 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I25_12495 4c0a6eaf627705fd638995a447a6ab9d 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 3.4E-92 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 C2I25_12495 4c0a6eaf627705fd638995a447a6ab9d 429 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.1E-170 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_03640 3555b30e96660bb2b451cd88f23cbc85 200 TIGRFAM TIGR00648 recU: recombination protein U 29 196 1.8E-77 T 14-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 C2I25_03640 3555b30e96660bb2b451cd88f23cbc85 200 Pfam PF03838 Recombination protein U 30 195 8.8E-68 T 14-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 C2I25_03640 3555b30e96660bb2b451cd88f23cbc85 200 SUPERFAMILY SSF52980 32 198 2.01E-67 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I25_03640 3555b30e96660bb2b451cd88f23cbc85 200 Gene3D G3DSA:3.40.1350.10 33 200 6.6E-68 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 C2I25_03640 3555b30e96660bb2b451cd88f23cbc85 200 PIRSF PIRSF037785 22 200 2.5E-76 T 14-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 C2I25_03640 3555b30e96660bb2b451cd88f23cbc85 200 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 200 102.001 T 14-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 C2I25_15160 e351bfb937f980d4e8597aa7f85de744 192 Gene3D G3DSA:2.40.40.60 61 157 4.5E-42 T 14-10-2018 C2I25_15160 e351bfb937f980d4e8597aa7f85de744 192 Pfam PF17294 Uncharacterised lipoprotein family 28 191 3.3E-51 T 14-10-2018 IPR035253 Putative lipoprotein, bacteria C2I25_15160 e351bfb937f980d4e8597aa7f85de744 192 Gene3D G3DSA:3.30.70.3060 32 180 4.5E-42 T 14-10-2018 C2I25_02200 a21520834c31034cebd4c86952651f81 131 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 8.3E-48 T 14-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 C2I25_02200 a21520834c31034cebd4c86952651f81 131 Gene3D G3DSA:3.40.140.10 1 131 4.9E-55 T 14-10-2018 C2I25_02200 a21520834c31034cebd4c86952651f81 131 SUPERFAMILY SSF53927 2 130 4.52E-48 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_02200 a21520834c31034cebd4c86952651f81 131 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I25_02200 a21520834c31034cebd4c86952651f81 131 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 102 1.6E-19 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I25_05305 6eb5ebf4c57038968b38ce8fadd6354e 256 PIRSF PIRSF000094 1 256 3.2E-103 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I25_05305 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_05305 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_05305 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_05305 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_05305 6eb5ebf4c57038968b38ce8fadd6354e 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.5E-87 T 14-10-2018 C2I25_05305 6eb5ebf4c57038968b38ce8fadd6354e 256 Gene3D G3DSA:3.40.50.720 1 256 2.1E-61 T 14-10-2018 C2I25_05305 6eb5ebf4c57038968b38ce8fadd6354e 256 SUPERFAMILY SSF51735 5 254 9.74E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_10130 635ca96517492580e4618377bdc24e58 647 Pfam PF12848 ABC transporter 237 323 1.7E-24 T 14-10-2018 IPR032781 ABC-transporter extension domain C2I25_10130 635ca96517492580e4618377bdc24e58 647 Pfam PF16326 ABC transporter C-terminal domain 580 645 1.3E-14 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 C2I25_10130 635ca96517492580e4618377bdc24e58 647 Gene3D G3DSA:1.10.287.380 561 647 1.8E-6 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 C2I25_10130 635ca96517492580e4618377bdc24e58 647 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10130 635ca96517492580e4618377bdc24e58 647 SUPERFAMILY SSF52540 319 542 1.55E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10130 635ca96517492580e4618377bdc24e58 647 Gene3D G3DSA:3.40.50.300 296 560 1.0E-59 T 14-10-2018 C2I25_10130 635ca96517492580e4618377bdc24e58 647 SUPERFAMILY SSF52540 7 251 1.35E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10130 635ca96517492580e4618377bdc24e58 647 ProSitePatterns PS00211 ABC transporters family signature. 451 465 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10130 635ca96517492580e4618377bdc24e58 647 Gene3D G3DSA:3.40.50.300 4 292 6.6E-67 T 14-10-2018 C2I25_10130 635ca96517492580e4618377bdc24e58 647 Pfam PF00005 ABC transporter 350 479 6.5E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10130 635ca96517492580e4618377bdc24e58 647 Pfam PF00005 ABC transporter 22 198 3.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10130 635ca96517492580e4618377bdc24e58 647 SMART SM00382 31 243 3.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_10130 635ca96517492580e4618377bdc24e58 647 SMART SM00382 358 523 1.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_03185 fb0cfa1b39cf2e3767c10ee7d6a39004 154 Gene3D G3DSA:1.20.120.490 29 153 2.4E-25 T 14-10-2018 IPR024042 TM1646-like domain superfamily C2I25_03185 fb0cfa1b39cf2e3767c10ee7d6a39004 154 SUPERFAMILY SSF158397 36 153 8.5E-26 T 14-10-2018 IPR024042 TM1646-like domain superfamily C2I25_03185 fb0cfa1b39cf2e3767c10ee7d6a39004 154 Pfam PF03885 Protein of unknown function (DUF327) 26 153 1.3E-24 T 14-10-2018 IPR005585 Protein of unknown function DUF327 C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 SUPERFAMILY SSF52540 816 1043 2.17E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 Gene3D G3DSA:1.20.1560.10 497 809 1.8E-18 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 Gene3D G3DSA:3.40.710.10 29 380 6.8E-99 T 14-10-2018 C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 SUPERFAMILY SSF56601 37 383 1.57E-80 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 Pfam PF00144 Beta-lactamase 42 365 2.5E-67 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 512 1033 5.4E-115 T 14-10-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015833|GO:0016021|GO:1904680 C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 Pfam PF00005 ABC transporter 847 979 2.8E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 SMART SM00382 854 1028 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 SUPERFAMILY SSF90123 511 801 1.7E-24 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_02055 e34d2ad68b54cee611003d6e8a0124e8 1055 Gene3D G3DSA:3.40.50.300 819 1053 3.2E-38 T 14-10-2018 C2I25_08650 f7b3766e56133288723a9bfea4e9c9f2 310 Gene3D G3DSA:1.10.3720.10 68 308 1.1E-67 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_08650 f7b3766e56133288723a9bfea4e9c9f2 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 305 4.7E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_08650 f7b3766e56133288723a9bfea4e9c9f2 310 SUPERFAMILY SSF161098 71 298 1.83E-57 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_00540 aa936f7bdfcab536cc361386c51e09e1 243 Pfam PF12811 Bax inhibitor 1 like 5 240 3.4E-71 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 C2I25_00540 aa936f7bdfcab536cc361386c51e09e1 243 PIRSF PIRSF009160 1 243 5.2E-92 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 C2I25_04385 577231a3807c2157a270c9888715ee83 420 SUPERFAMILY SSF55681 7 328 1.15E-60 T 14-10-2018 C2I25_04385 577231a3807c2157a270c9888715ee83 420 Pfam PF13393 Histidyl-tRNA synthetase 11 320 3.5E-72 T 14-10-2018 C2I25_04385 577231a3807c2157a270c9888715ee83 420 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 13 325 3.4E-104 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 C2I25_04385 577231a3807c2157a270c9888715ee83 420 Gene3D G3DSA:3.30.930.10 2 325 4.6E-88 T 14-10-2018 C2I25_04385 577231a3807c2157a270c9888715ee83 420 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 378 37.037 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 C2I25_04385 577231a3807c2157a270c9888715ee83 420 PIRSF PIRSF001549 2 413 1.9E-74 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 C2I25_04415 4729862d13ef11870e05f8bd7e61bae0 169 Gene3D G3DSA:3.30.70.260 1 80 1.3E-29 T 14-10-2018 C2I25_04415 4729862d13ef11870e05f8bd7e61bae0 169 Pfam PF10369 Small subunit of acetolactate synthase 85 156 4.3E-26 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I25_04415 4729862d13ef11870e05f8bd7e61bae0 169 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 1.0E-28 T 14-10-2018 C2I25_04415 4729862d13ef11870e05f8bd7e61bae0 169 SUPERFAMILY SSF55021 2 77 6.2E-19 T 14-10-2018 C2I25_04415 4729862d13ef11870e05f8bd7e61bae0 169 Gene3D G3DSA:3.30.70.1150 84 164 1.7E-27 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal C2I25_04415 4729862d13ef11870e05f8bd7e61bae0 169 SUPERFAMILY SSF55021 77 157 5.04E-24 T 14-10-2018 C2I25_04415 4729862d13ef11870e05f8bd7e61bae0 169 Pfam PF13710 ACT domain 12 74 8.4E-14 T 14-10-2018 C2I25_04415 4729862d13ef11870e05f8bd7e61bae0 169 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 157 2.9E-59 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I25_00310 086e753ed107b19e0474f318852a07d4 236 Pfam PF00005 ABC transporter 19 152 2.2E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_00310 086e753ed107b19e0474f318852a07d4 236 SMART SM00382 27 201 6.9E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_00310 086e753ed107b19e0474f318852a07d4 236 SUPERFAMILY SSF52540 17 211 6.52E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_00310 086e753ed107b19e0474f318852a07d4 236 Gene3D G3DSA:3.40.50.300 1 222 3.2E-46 T 14-10-2018 C2I25_05935 ee519fa841763d6cfd38923c6c23a046 275 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 4 265 3.3E-99 T 14-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 C2I25_05935 ee519fa841763d6cfd38923c6c23a046 275 SUPERFAMILY SSF161098 13 263 1.68E-58 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05935 ee519fa841763d6cfd38923c6c23a046 275 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 6 269 5.0E-128 T 14-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 C2I25_05935 ee519fa841763d6cfd38923c6c23a046 275 Gene3D G3DSA:1.10.3720.10 12 271 7.8E-71 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05935 ee519fa841763d6cfd38923c6c23a046 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 267 2.5E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 Gene3D G3DSA:3.40.1160.10 1 263 1.1E-78 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 Pfam PF00696 Amino acid kinase family 4 232 1.0E-42 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 PIRSF PIRSF000729 1 367 1.4E-147 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 SUPERFAMILY SSF53633 4 254 1.03E-64 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 Pfam PF01472 PUA domain 277 347 6.2E-21 T 14-10-2018 IPR002478 PUA domain GO:0003723 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 1.8E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 1.8E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 1.8E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 1.8E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 1.8E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 SUPERFAMILY SSF88697 277 366 7.73E-20 T 14-10-2018 IPR015947 PUA-like superfamily C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 Gene3D G3DSA:2.30.130.10 266 366 2.8E-28 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 260 36.151 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 365 2.8E-136 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 14-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I25_24630 b384c0f4ce4220476ed14d0178784a45 367 SMART SM00359 277 359 1.9E-15 T 14-10-2018 IPR002478 PUA domain GO:0003723 C2I25_16985 14d6eff7a9b5b116724df1f8cb28c899 341 Pfam PF01636 Phosphotransferase enzyme family 33 245 5.2E-8 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_16985 14d6eff7a9b5b116724df1f8cb28c899 341 Gene3D G3DSA:3.90.1200.10 99 326 1.7E-22 T 14-10-2018 C2I25_16985 14d6eff7a9b5b116724df1f8cb28c899 341 SUPERFAMILY SSF56112 12 307 5.1E-22 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_16985 14d6eff7a9b5b116724df1f8cb28c899 341 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 9 320 1.8E-135 T 14-10-2018 IPR014253 Spore coat protein YsxE C2I25_16985 14d6eff7a9b5b116724df1f8cb28c899 341 Gene3D G3DSA:3.30.200.20 3 95 6.6E-15 T 14-10-2018 C2I25_18730 28a5e0d19565e7eebfd99072d610f23d 219 Pfam PF01842 ACT domain 149 208 8.6E-11 T 14-10-2018 IPR002912 ACT domain C2I25_18730 28a5e0d19565e7eebfd99072d610f23d 219 Pfam PF03315 Serine dehydratase beta chain 5 81 2.0E-14 T 14-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 C2I25_18730 28a5e0d19565e7eebfd99072d610f23d 219 SUPERFAMILY SSF55021 136 217 4.2E-16 T 14-10-2018 C2I25_18730 28a5e0d19565e7eebfd99072d610f23d 219 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 1.1E-81 T 14-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 C2I25_18730 28a5e0d19565e7eebfd99072d610f23d 219 SUPERFAMILY SSF143548 19 137 3.01E-32 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 C2I25_18730 28a5e0d19565e7eebfd99072d610f23d 219 Gene3D G3DSA:3.30.1330.90 13 136 2.5E-22 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 C2I25_18730 28a5e0d19565e7eebfd99072d610f23d 219 PIRSF PIRSF036692 1 219 2.2E-107 T 14-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 C2I25_18730 28a5e0d19565e7eebfd99072d610f23d 219 Gene3D G3DSA:3.30.70.260 147 219 5.6E-16 T 14-10-2018 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 SUPERFAMILY SSF51735 6 158 3.3E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 342 36.425 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 SMART SM00859 7 123 1.4E-41 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 328 1.6E-54 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 SUPERFAMILY SSF55347 131 329 1.05E-71 T 14-10-2018 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 Gene3D G3DSA:3.40.50.720 8 339 1.6E-135 T 14-10-2018 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 122 3.5E-33 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 14-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 PIRSF PIRSF000148 5 347 2.3E-122 T 14-10-2018 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 Gene3D G3DSA:3.30.360.10 130 325 1.6E-135 T 14-10-2018 C2I25_27885 2d976f3a6d08d2f1326c2fda5ee4c45e 347 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 343 2.2E-143 T 14-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 SUPERFAMILY SSF52540 3 225 4.96E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 SUPERFAMILY SSF52540 256 489 9.8E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 SMART SM00382 29 218 1.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 Gene3D G3DSA:3.40.50.300 1 237 1.1E-56 T 14-10-2018 C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 Gene3D G3DSA:3.40.50.300 251 494 1.5E-41 T 14-10-2018 C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 Pfam PF00005 ABC transporter 21 169 4.3E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 Pfam PF00005 ABC transporter 274 429 1.1E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_20560 8b7bc9abc757a9cb11604021d556a623 510 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_09545 e47445a959866a060b6f0c94b60eac1b 210 Pfam PF04199 Putative cyclase 4 151 3.1E-26 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I25_09545 e47445a959866a060b6f0c94b60eac1b 210 SUPERFAMILY SSF102198 1 208 3.92E-60 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I25_09545 e47445a959866a060b6f0c94b60eac1b 210 Gene3D G3DSA:3.50.30.50 1 209 2.4E-65 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I25_10825 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 SUPERFAMILY SSF52540 26 252 3.96E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10825 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 Pfam PF00005 ABC transporter 43 190 9.8E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10825 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10825 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 27 294 2.9E-119 T 14-10-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 C2I25_10825 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 Gene3D G3DSA:3.40.50.300 22 300 2.9E-80 T 14-10-2018 C2I25_10825 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 SMART SM00382 52 238 6.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_11355 a8f8b656e69ef094e62b52eaae557321 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 C2I25_11355 a8f8b656e69ef094e62b52eaae557321 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 38.653 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 C2I25_11355 a8f8b656e69ef094e62b52eaae557321 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 186 5.6E-73 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 C2I25_11355 a8f8b656e69ef094e62b52eaae557321 186 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 1.1E-61 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 C2I25_11355 a8f8b656e69ef094e62b52eaae557321 186 Gene3D G3DSA:3.40.50.1470 1 186 7.6E-74 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 C2I25_11355 a8f8b656e69ef094e62b52eaae557321 186 SUPERFAMILY SSF53178 1 185 6.54E-73 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 C2I25_11355 a8f8b656e69ef094e62b52eaae557321 186 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 C2I25_01590 2696a5003fae3f2be04d0f2660db688d 115 ProDom PD866859 YTVB PLASMID MEMBRANE TRANSMEMBRANE 3 105 5.0E-53 T 14-10-2018 C2I25_01590 2696a5003fae3f2be04d0f2660db688d 115 Pfam PF14074 Protein of unknown function (DUF4257) 6 86 4.9E-32 T 14-10-2018 IPR025353 Protein of unknown function DUF4257) C2I25_24220 97a4ee159ff7c7f5da5ba51aa800b6a4 237 SMART SM00796 1 211 7.5E-99 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D C2I25_24220 97a4ee159ff7c7f5da5ba51aa800b6a4 237 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 220 8.4E-70 T 14-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I25_24220 97a4ee159ff7c7f5da5ba51aa800b6a4 237 Gene3D G3DSA:2.40.100.10 96 236 3.0E-57 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_24220 97a4ee159ff7c7f5da5ba51aa800b6a4 237 Gene3D G3DSA:3.30.1360.40 1 94 4.4E-26 T 14-10-2018 C2I25_24220 97a4ee159ff7c7f5da5ba51aa800b6a4 237 SUPERFAMILY SSF50891 98 227 9.1E-45 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_24220 97a4ee159ff7c7f5da5ba51aa800b6a4 237 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 210 2.0E-75 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D C2I25_24220 97a4ee159ff7c7f5da5ba51aa800b6a4 237 SUPERFAMILY SSF160467 2 102 3.92E-17 T 14-10-2018 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 Gene3D G3DSA:3.30.930.10 106 461 2.9E-117 T 14-10-2018 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 463 1.3E-191 T 14-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 SUPERFAMILY SSF55681 104 460 2.58E-100 T 14-10-2018 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 378 394 2.9E-12 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 418 432 2.9E-12 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 217 2.9E-12 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 221 234 2.9E-12 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 463 46.365 T 14-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 SUPERFAMILY SSF50249 13 102 7.91E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 Gene3D G3DSA:2.40.50.140 2 105 1.8E-22 T 14-10-2018 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 Pfam PF01336 OB-fold nucleic acid binding domain 21 97 1.4E-10 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I25_16515 fa1be445e81f14560e6ed7bfd22cef47 463 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 457 2.9E-89 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_09170 4d0854d2cb1bd2381184e422d6f5a2bf 287 SMART SM00478 127 286 1.5E-11 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I25_09170 4d0854d2cb1bd2381184e422d6f5a2bf 287 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 124 261 1.3E-16 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I25_09170 4d0854d2cb1bd2381184e422d6f5a2bf 287 Gene3D G3DSA:1.10.1670.40 235 284 1.5E-46 T 14-10-2018 C2I25_09170 4d0854d2cb1bd2381184e422d6f5a2bf 287 Gene3D G3DSA:1.10.340.30 115 234 1.5E-46 T 14-10-2018 C2I25_09170 4d0854d2cb1bd2381184e422d6f5a2bf 287 SUPERFAMILY SSF48150 113 284 8.37E-36 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 C2I25_10565 57bf9afb5355145f0bb371752a46306b 336 Gene3D G3DSA:3.40.50.300 1 335 7.2E-96 T 14-10-2018 C2I25_10565 57bf9afb5355145f0bb371752a46306b 336 Pfam PF00005 ABC transporter 25 182 2.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10565 57bf9afb5355145f0bb371752a46306b 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 2.5E-17 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_10565 57bf9afb5355145f0bb371752a46306b 336 SUPERFAMILY SSF52540 4 254 9.16E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10565 57bf9afb5355145f0bb371752a46306b 336 SMART SM00382 33 232 3.8E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_10565 57bf9afb5355145f0bb371752a46306b 336 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10565 57bf9afb5355145f0bb371752a46306b 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.2E-23 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_05540 d77e3629b809f709583a28acac2ae1c6 290 SUPERFAMILY SSF51735 12 233 2.54E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_05540 d77e3629b809f709583a28acac2ae1c6 290 Gene3D G3DSA:3.40.50.720 9 289 9.7E-19 T 14-10-2018 C2I25_01830 22c0fbebf695c06af7e5332d632afc73 225 SUPERFAMILY SSF46894 128 222 1.67E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_01830 22c0fbebf695c06af7e5332d632afc73 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 4.7E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_01830 22c0fbebf695c06af7e5332d632afc73 225 SUPERFAMILY SSF52172 3 163 1.25E-43 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_01830 22c0fbebf695c06af7e5332d632afc73 225 SMART SM00448 3 113 5.1E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_01830 22c0fbebf695c06af7e5332d632afc73 225 Gene3D G3DSA:1.10.10.10 127 225 1.8E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01830 22c0fbebf695c06af7e5332d632afc73 225 SMART SM00862 146 221 1.1E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_01830 22c0fbebf695c06af7e5332d632afc73 225 Gene3D G3DSA:3.40.50.2300 2 126 1.6E-38 T 14-10-2018 C2I25_01830 22c0fbebf695c06af7e5332d632afc73 225 Pfam PF00072 Response regulator receiver domain 5 113 6.9E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_20390 b68d996f6ce6a17c030a278924b05ae3 185 Pfam PF01765 Ribosome recycling factor 21 183 3.3E-65 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 C2I25_20390 b68d996f6ce6a17c030a278924b05ae3 185 Gene3D G3DSA:1.10.132.20 12 182 1.8E-71 T 14-10-2018 C2I25_20390 b68d996f6ce6a17c030a278924b05ae3 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 1.2E-77 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 C2I25_20390 b68d996f6ce6a17c030a278924b05ae3 185 Gene3D G3DSA:3.30.1360.40 31 105 1.8E-71 T 14-10-2018 C2I25_20390 b68d996f6ce6a17c030a278924b05ae3 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.238 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 C2I25_20390 b68d996f6ce6a17c030a278924b05ae3 185 SUPERFAMILY SSF55194 5 184 2.35E-71 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 C2I25_26835 1f55e12aeb5783dba2fcd7eca1bfd6c4 324 SUPERFAMILY SSF55874 163 324 5.9E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_26835 1f55e12aeb5783dba2fcd7eca1bfd6c4 324 Gene3D G3DSA:3.30.565.10 176 324 2.3E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_26835 1f55e12aeb5783dba2fcd7eca1bfd6c4 324 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 268 1.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26835 1f55e12aeb5783dba2fcd7eca1bfd6c4 324 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 282 1.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26835 1f55e12aeb5783dba2fcd7eca1bfd6c4 324 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 1.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26835 1f55e12aeb5783dba2fcd7eca1bfd6c4 324 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 324 1.1E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26835 1f55e12aeb5783dba2fcd7eca1bfd6c4 324 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 323 3.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_26835 1f55e12aeb5783dba2fcd7eca1bfd6c4 324 SMART SM00387 216 324 1.4E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15835 ecfebf1a0fc5df6cb825724f2a8d61e5 137 SUPERFAMILY SSF46955 2 121 2.82E-27 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_15835 ecfebf1a0fc5df6cb825724f2a8d61e5 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 1.0E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15835 ecfebf1a0fc5df6cb825724f2a8d61e5 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 1.0E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15835 ecfebf1a0fc5df6cb825724f2a8d61e5 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.0E-8 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15835 ecfebf1a0fc5df6cb825724f2a8d61e5 137 SMART SM00422 2 70 2.4E-23 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15835 ecfebf1a0fc5df6cb825724f2a8d61e5 137 Pfam PF13411 MerR HTH family regulatory protein 2 65 5.4E-19 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15835 ecfebf1a0fc5df6cb825724f2a8d61e5 137 Gene3D G3DSA:1.10.1660.10 1 128 9.7E-32 T 14-10-2018 C2I25_22695 37cfc8901e9111e83f1e73f1babb198e 138 SUPERFAMILY SSF55961 1 135 3.49E-37 T 14-10-2018 C2I25_22695 37cfc8901e9111e83f1e73f1babb198e 138 Gene3D G3DSA:3.30.530.20 1 138 3.5E-48 T 14-10-2018 IPR023393 START-like domain superfamily C2I25_22695 37cfc8901e9111e83f1e73f1babb198e 138 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 135 9.0E-25 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 856 919 8.63E-7 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 756 847 1.7E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1685 1777 3.7E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1592 1684 8.7E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 2245 2334 8.3E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 941 1032 5.5E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 2058 2148 9.9E-23 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1778 1869 7.7E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 848 939 1.1E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1130 1218 1.0E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 950 1014 2.59E-9 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1135 1199 8.63E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1786 1851 3.18E-7 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 2065 2129 8.63E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 764 828 3.92E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1043 1107 1.49E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 661 755 1.1E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1414 1479 6.28E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 327 461 4.3E-18 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 2254 2313 3.53E-7 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 482 569 1.5E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1409 1497 9.6E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1316 1408 7.2E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1872 1965 1.8E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1221 1315 1.2E-19 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 2151 2244 1.0E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1966 2057 4.5E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1035 1129 6.5E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 570 660 1.6E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.10 1498 1590 7.7E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.1280 31 175 4.7E-26 T 14-10-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 670 734 1.14E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1693 1758 3.14E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1321 1386 4.71E-9 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Pfam PF11766 Cell-wall agglutinin N-terminal ligand-sugar binding 71 141 2.0E-7 T 14-10-2018 IPR024672 Agglutinin-like protein, N-terminal C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49401 36 170 2.36E-29 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1600 1665 7.06E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1507 1572 2.35E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Gene3D G3DSA:2.60.40.740 328 475 3.5E-22 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1973 2037 2.9E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2392 2424 0.0021 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1228 1293 3.92E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 Pfam PF05737 Collagen binding domain 183 307 2.2E-18 T 14-10-2018 IPR008456 Collagen binding domain GO:0005518 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 1880 1943 2.47E-8 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49401 182 317 3.98E-27 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 491 554 1.57E-6 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 2158 2223 9.02E-9 T 14-10-2018 C2I25_06095 3c37469bd1e0e32173e5bc3d63f298b3 2426 SUPERFAMILY SSF49478 581 645 5.49E-8 T 14-10-2018 C2I25_10145 a1b831eaf94db5a5e1935b00c39abf9c 230 SUPERFAMILY SSF53067 1 101 1.12E-28 T 14-10-2018 C2I25_10145 a1b831eaf94db5a5e1935b00c39abf9c 230 Gene3D G3DSA:3.30.420.40 95 189 5.9E-50 T 14-10-2018 C2I25_10145 a1b831eaf94db5a5e1935b00c39abf9c 230 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 8.6E-56 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 C2I25_10145 a1b831eaf94db5a5e1935b00c39abf9c 230 Gene3D G3DSA:3.30.420.40 3 216 5.9E-50 T 14-10-2018 C2I25_10145 a1b831eaf94db5a5e1935b00c39abf9c 230 Pfam PF00814 Glycoprotease family 32 224 2.8E-37 T 14-10-2018 IPR000905 Gcp-like domain C2I25_10145 a1b831eaf94db5a5e1935b00c39abf9c 230 SUPERFAMILY SSF53067 108 214 5.05E-15 T 14-10-2018 C2I25_19895 65fd87c63d8f020f255f49c64154ff33 296 SUPERFAMILY SSF51735 3 160 7.12E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_19895 65fd87c63d8f020f255f49c64154ff33 296 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 175 293 5.6E-30 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain C2I25_19895 65fd87c63d8f020f255f49c64154ff33 296 SUPERFAMILY SSF48179 174 294 3.13E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_19895 65fd87c63d8f020f255f49c64154ff33 296 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 4 294 2.9E-72 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 C2I25_19895 65fd87c63d8f020f255f49c64154ff33 296 Gene3D G3DSA:1.10.1040.10 174 296 4.9E-40 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_19895 65fd87c63d8f020f255f49c64154ff33 296 Gene3D G3DSA:3.40.50.720 1 173 1.6E-42 T 14-10-2018 C2I25_19895 65fd87c63d8f020f255f49c64154ff33 296 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 147 3.1E-29 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain C2I25_08375 e38e001ff3cad26674c54eb8b6b3e046 140 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_08375 e38e001ff3cad26674c54eb8b6b3e046 140 Gene3D G3DSA:3.90.79.10 2 122 4.7E-28 T 14-10-2018 C2I25_08375 e38e001ff3cad26674c54eb8b6b3e046 140 Pfam PF00293 NUDIX domain 5 112 1.6E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_08375 e38e001ff3cad26674c54eb8b6b3e046 140 SUPERFAMILY SSF55811 2 110 2.71E-26 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_08375 e38e001ff3cad26674c54eb8b6b3e046 140 PRINTS PR00502 NUDIX hydrolase family signature 30 44 3.4E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_08375 e38e001ff3cad26674c54eb8b6b3e046 140 PRINTS PR00502 NUDIX hydrolase family signature 44 59 3.4E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_21515 f738b35eb31c0942c4f603490ea0c288 44 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 1 44 15.192 T 14-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 C2I25_21515 f738b35eb31c0942c4f603490ea0c288 44 Pfam PF08177 Small acid-soluble spore protein N family 1 43 1.8E-21 T 14-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 Gene3D G3DSA:3.40.50.970 314 489 3.5E-66 T 14-10-2018 C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 SUPERFAMILY SSF52518 5 378 5.26E-74 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 278 7.1E-119 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 SUPERFAMILY SSF52922 490 623 1.24E-32 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 Pfam PF02780 Transketolase, C-terminal domain 493 615 3.3E-30 T 14-10-2018 IPR033248 Transketolase, C-terminal domain C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 44.885 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 623 8.4E-295 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 Gene3D G3DSA:3.40.50.920 493 627 1.7E-37 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 SMART SM00861 316 481 1.6E-64 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 1.0E-38 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 SUPERFAMILY SSF52518 317 502 5.17E-53 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_18435 c0b9194f73d3ade40d856ededfee26ca 630 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_05315 24a33d7aec51ec27fed03dae5ebf3caf 323 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 306 6.7E-93 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_05315 24a33d7aec51ec27fed03dae5ebf3caf 323 Gene3D G3DSA:3.90.25.10 192 313 1.3E-129 T 14-10-2018 C2I25_05315 24a33d7aec51ec27fed03dae5ebf3caf 323 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 320 1.1E-151 T 14-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 C2I25_05315 24a33d7aec51ec27fed03dae5ebf3caf 323 SUPERFAMILY SSF51735 1 317 2.94E-92 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_05315 24a33d7aec51ec27fed03dae5ebf3caf 323 Gene3D G3DSA:3.40.50.720 2 305 1.3E-129 T 14-10-2018 C2I25_00805 b2da38040065458347fc7865a87d9833 178 Pfam PF00589 Phage integrase family 9 167 1.7E-24 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_00805 b2da38040065458347fc7865a87d9833 178 Gene3D G3DSA:1.10.443.10 5 178 1.8E-32 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_00805 b2da38040065458347fc7865a87d9833 178 SUPERFAMILY SSF56349 6 177 1.29E-38 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_06850 1742264670efbedb7924bd1636ebd9c3 326 Pfam PF00005 ABC transporter 37 187 1.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_06850 1742264670efbedb7924bd1636ebd9c3 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 305 4.5E-20 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_06850 1742264670efbedb7924bd1636ebd9c3 326 Gene3D G3DSA:3.40.50.300 7 326 1.2E-105 T 14-10-2018 C2I25_06850 1742264670efbedb7924bd1636ebd9c3 326 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_06850 1742264670efbedb7924bd1636ebd9c3 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 325 2.5E-30 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_06850 1742264670efbedb7924bd1636ebd9c3 326 SMART SM00382 45 237 2.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_06850 1742264670efbedb7924bd1636ebd9c3 326 SUPERFAMILY SSF52540 9 259 1.03E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05720 e88d16e606267916e3c9574387762535 187 ProSitePatterns PS00760 Signal peptidases I lysine active site. 81 93 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I25_05720 e88d16e606267916e3c9574387762535 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 2.1E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_05720 e88d16e606267916e3c9574387762535 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 91 2.1E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_05720 e88d16e606267916e3c9574387762535 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 2.1E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_05720 e88d16e606267916e3c9574387762535 187 Gene3D G3DSA:2.10.109.10 59 187 1.5E-50 T 14-10-2018 C2I25_05720 e88d16e606267916e3c9574387762535 187 Pfam PF00717 Peptidase S24-like 36 103 8.4E-22 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I25_05720 e88d16e606267916e3c9574387762535 187 SUPERFAMILY SSF51306 27 180 3.03E-53 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I25_05720 e88d16e606267916e3c9574387762535 187 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 177 7.2E-54 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_05720 e88d16e606267916e3c9574387762535 187 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I25_05720 e88d16e606267916e3c9574387762535 187 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I25_03810 044012053543d4615586a4091d153ed8 370 SUPERFAMILY SSF53383 14 358 5.42E-82 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_03810 044012053543d4615586a4091d153ed8 370 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 357 5.4E-111 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 C2I25_03810 044012053543d4615586a4091d153ed8 370 Gene3D G3DSA:3.40.640.10 43 267 1.6E-113 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_03810 044012053543d4615586a4091d153ed8 370 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 C2I25_03810 044012053543d4615586a4091d153ed8 370 Gene3D G3DSA:3.90.1150.10 20 351 1.6E-113 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_03810 044012053543d4615586a4091d153ed8 370 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 359 61.965 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 C2I25_03810 044012053543d4615586a4091d153ed8 370 Pfam PF00155 Aminotransferase class I and II 30 352 1.0E-58 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_04695 b3081e5dfa8576ac9b6e738d75225a55 165 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 27 138 9.9E-57 T 14-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 C2I25_04695 b3081e5dfa8576ac9b6e738d75225a55 165 Pfam PF14489 QueF-like protein 62 140 8.9E-36 T 14-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 C2I25_04695 b3081e5dfa8576ac9b6e738d75225a55 165 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 165 72.226 T 14-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 C2I25_04695 b3081e5dfa8576ac9b6e738d75225a55 165 SUPERFAMILY SSF55620 27 134 2.89E-28 T 14-10-2018 C2I25_04695 b3081e5dfa8576ac9b6e738d75225a55 165 Gene3D G3DSA:3.30.1130.10 21 165 6.4E-69 T 14-10-2018 C2I25_04695 b3081e5dfa8576ac9b6e738d75225a55 165 PIRSF PIRSF027377 8 147 6.8E-63 T 14-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 C2I25_25045 087052d59dc979e0a490177dd08cebf0 290 SMART SM00382 28 206 1.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_25045 087052d59dc979e0a490177dd08cebf0 290 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_25045 087052d59dc979e0a490177dd08cebf0 290 Gene3D G3DSA:3.40.50.300 2 232 1.5E-42 T 14-10-2018 C2I25_25045 087052d59dc979e0a490177dd08cebf0 290 SUPERFAMILY SSF52540 3 221 1.12E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25045 087052d59dc979e0a490177dd08cebf0 290 Pfam PF00005 ABC transporter 20 156 1.5E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_18980 b7194c95634df31118eb1f343b8b1142 179 PRINTS PR00502 NUDIX hydrolase family signature 72 86 3.5E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_18980 b7194c95634df31118eb1f343b8b1142 179 PRINTS PR00502 NUDIX hydrolase family signature 86 101 3.5E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_18980 b7194c95634df31118eb1f343b8b1142 179 Gene3D G3DSA:3.90.79.10 4 179 5.4E-55 T 14-10-2018 C2I25_18980 b7194c95634df31118eb1f343b8b1142 179 SUPERFAMILY SSF55811 8 178 1.9E-51 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_18980 b7194c95634df31118eb1f343b8b1142 179 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_18980 b7194c95634df31118eb1f343b8b1142 179 Pfam PF00293 NUDIX domain 43 164 2.7E-22 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_05635 aa56eb0c359f999d356f6ebd365a5ccb 319 SUPERFAMILY SSF53800 3 305 8.01E-89 T 14-10-2018 C2I25_05635 aa56eb0c359f999d356f6ebd365a5ccb 319 ProSitePatterns PS00534 Ferrochelatase signature. 176 194 - T 14-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I25_05635 aa56eb0c359f999d356f6ebd365a5ccb 319 Gene3D G3DSA:3.40.50.1400 148 287 7.7E-102 T 14-10-2018 C2I25_05635 aa56eb0c359f999d356f6ebd365a5ccb 319 Gene3D G3DSA:3.40.50.1400 8 302 7.7E-102 T 14-10-2018 C2I25_05635 aa56eb0c359f999d356f6ebd365a5ccb 319 TIGRFAM TIGR00109 hemH: ferrochelatase 2 305 2.6E-91 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I25_05635 aa56eb0c359f999d356f6ebd365a5ccb 319 Hamap MF_00323 Ferrochelatase [hemH]. 4 306 31.554 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I25_05635 aa56eb0c359f999d356f6ebd365a5ccb 319 Pfam PF00762 Ferrochelatase 5 305 6.9E-82 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 4.1E-39 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 4.1E-39 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 4.1E-39 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 4.1E-39 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 4.1E-39 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 151 4.9E-48 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 148 8.0E-81 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 32.877 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 Gene3D G3DSA:3.30.1360.80 1 157 6.6E-59 T 14-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 SUPERFAMILY SSF63411 4 152 1.74E-58 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I25_15225 fe6d3d15bc78938f5e83751d3104569f 157 PIRSF PIRSF006160 1 157 7.8E-59 T 14-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 301 5.2E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 SMART SM00387 346 452 3.7E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 5.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 5.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 5.7E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 SUPERFAMILY SSF55874 292 452 7.47E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 Gene3D G3DSA:1.10.287.130 240 299 5.4E-17 T 14-10-2018 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 SMART SM00304 182 234 5.2E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 Gene3D G3DSA:1.20.1480.50 145 239 5.9E-9 T 14-10-2018 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 Gene3D G3DSA:3.30.565.10 300 452 2.3E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 SUPERFAMILY SSF158472 184 229 7.72E-7 T 14-10-2018 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 SMART SM00388 235 302 2.1E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 SUPERFAMILY SSF47384 218 303 2.16E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_01740 87f10448c7292b9572448a1245e8b98b 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 452 1.7E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_01630 95ffa668c08ae65740bba4ec7d164d49 272 Gene3D G3DSA:3.40.50.620 1 272 5.7E-91 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_01630 95ffa668c08ae65740bba4ec7d164d49 272 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 266 49.693 T 14-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 C2I25_01630 95ffa668c08ae65740bba4ec7d164d49 272 TIGRFAM TIGR00552 nadE: NAD+ synthetase 18 272 2.5E-81 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 C2I25_01630 95ffa668c08ae65740bba4ec7d164d49 272 SUPERFAMILY SSF52402 3 271 8.87E-83 T 14-10-2018 C2I25_01630 95ffa668c08ae65740bba4ec7d164d49 272 Pfam PF02540 NAD synthase 23 263 2.2E-76 T 14-10-2018 IPR022310 NAD/GMP synthase C2I25_17570 580d488facd12195672eb2bcc2da38b8 497 Pfam PF16244 Domain of unknown function (DUF4901) 11 239 4.5E-107 T 14-10-2018 IPR032599 Protein of unknown function DUF4901 C2I25_17115 cda28c5631a6469dc0b01780dcc63c10 180 Gene3D G3DSA:3.30.1340.20 75 180 1.1E-37 T 14-10-2018 IPR035922 3H domain superfamily C2I25_17115 cda28c5631a6469dc0b01780dcc63c10 180 Pfam PF02829 3H domain 82 178 5.4E-36 T 14-10-2018 IPR004173 3H domain GO:0036094 C2I25_17115 cda28c5631a6469dc0b01780dcc63c10 180 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 85 179 8.0E-51 T 14-10-2018 IPR004173 3H domain GO:0036094 C2I25_17115 cda28c5631a6469dc0b01780dcc63c10 180 PIRSF PIRSF037847 9 180 8.2E-68 T 14-10-2018 IPR026043 Transcription repressor NadR C2I25_17115 cda28c5631a6469dc0b01780dcc63c10 180 SUPERFAMILY SSF46785 10 69 3.63E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_17115 cda28c5631a6469dc0b01780dcc63c10 180 SUPERFAMILY SSF75500 77 179 5.49E-38 T 14-10-2018 IPR035922 3H domain superfamily C2I25_17115 cda28c5631a6469dc0b01780dcc63c10 180 Gene3D G3DSA:1.10.10.10 1 69 2.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17115 cda28c5631a6469dc0b01780dcc63c10 180 Pfam PF08279 HTH domain 14 66 2.4E-15 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 C2I25_24730 361c85e2247cabb55a42a7e13a20b9b5 445 Gene3D G3DSA:3.30.43.10 10 88 6.3E-23 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 C2I25_24730 361c85e2247cabb55a42a7e13a20b9b5 445 Pfam PF08031 Berberine and berberine like 399 443 7.8E-21 T 14-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 C2I25_24730 361c85e2247cabb55a42a7e13a20b9b5 445 Pfam PF01565 FAD binding domain 35 169 3.1E-27 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I25_24730 361c85e2247cabb55a42a7e13a20b9b5 445 Gene3D G3DSA:3.30.465.50 93 443 3.9E-89 T 14-10-2018 C2I25_24730 361c85e2247cabb55a42a7e13a20b9b5 445 SUPERFAMILY SSF56176 9 201 2.34E-49 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_24730 361c85e2247cabb55a42a7e13a20b9b5 445 Gene3D G3DSA:3.40.462.20 204 396 3.9E-89 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 Pfam PF08191 LRR adjacent 716 758 0.0041 T 14-10-2018 IPR012569 Leucine-rich repeat-containing adjacent domain C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 Pfam PF08191 LRR adjacent 481 522 0.2 T 14-10-2018 IPR012569 Leucine-rich repeat-containing adjacent domain C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SUPERFAMILY SSF81296 450 524 6.06E-11 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00369 631 652 91.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00369 653 676 110.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00369 393 416 19.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00369 261 283 160.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00369 327 349 80.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 Gene3D G3DSA:2.60.40.1220 670 761 1.1E-14 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 Gene3D G3DSA:2.60.40.1220 427 525 3.3E-15 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 Gene3D G3DSA:2.60.40.1850 40 164 5.2E-36 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 327 348 41.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 261 282 49.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 609 630 390.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 283 304 31.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 305 326 91.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 349 370 12.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 393 414 240.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 371 392 280.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00365 415 436 250.0 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 961 992 3.7E-4 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SUPERFAMILY SSF158911 46 162 4.97E-29 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SUPERFAMILY SSF81296 689 760 4.43E-10 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 Pfam PF05031 Iron Transport-associated domain 44 162 3.7E-29 T 14-10-2018 IPR006635 NEAT domain C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 Gene3D G3DSA:3.80.10.10 171 384 3.9E-45 T 14-10-2018 IPR032675 Leucine-rich repeat domain superfamily C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 Gene3D G3DSA:3.80.10.10 559 669 1.5E-19 T 14-10-2018 IPR032675 Leucine-rich repeat domain superfamily C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SUPERFAMILY SSF52075 560 679 3.66E-22 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SUPERFAMILY SSF52058 216 433 3.29E-40 T 14-10-2018 C2I25_08730 a45b33c035abd3383f8f9805f74d8f47 996 SMART SM00725 44 168 4.4E-15 T 14-10-2018 IPR006635 NEAT domain C2I25_06855 85badf622b7c4fbe06aaa206b4974635 330 SUPERFAMILY SSF52540 33 317 9.35E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_06855 85badf622b7c4fbe06aaa206b4974635 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 1.2E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_06855 85badf622b7c4fbe06aaa206b4974635 330 Gene3D G3DSA:3.40.50.300 3 327 4.5E-97 T 14-10-2018 C2I25_06855 85badf622b7c4fbe06aaa206b4974635 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 1.3E-26 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_06855 85badf622b7c4fbe06aaa206b4974635 330 SMART SM00382 34 241 9.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_06855 85badf622b7c4fbe06aaa206b4974635 330 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_06855 85badf622b7c4fbe06aaa206b4974635 330 Pfam PF00005 ABC transporter 26 183 2.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 9 431 1.1E-121 T 14-10-2018 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 SUPERFAMILY SSF56176 7 185 2.85E-49 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 20 53 - T 14-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 Gene3D G3DSA:3.30.465.10 74 197 2.8E-35 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 Pfam PF01565 FAD binding domain 20 155 5.7E-29 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 Pfam PF04030 D-arabinono-1,4-lactone oxidase 179 429 1.8E-80 T 14-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 Gene3D G3DSA:3.30.70.2520 302 394 4.1E-26 T 14-10-2018 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 Gene3D G3DSA:3.30.43.10 4 72 1.0E-20 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 C2I25_08100 a78d4ad389f011999270038c23f30d2a 438 PIRSF PIRSF000136 1 436 2.9E-161 T 14-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 C2I25_09780 b606e463fb16f5de943b171fde5e71c3 160 SMART SM00347 22 124 6.6E-23 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_09780 b606e463fb16f5de943b171fde5e71c3 160 Gene3D G3DSA:1.10.10.10 11 157 2.3E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_09780 b606e463fb16f5de943b171fde5e71c3 160 Pfam PF01047 MarR family 31 89 1.3E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_09780 b606e463fb16f5de943b171fde5e71c3 160 SUPERFAMILY SSF46785 17 136 2.53E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_09780 b606e463fb16f5de943b171fde5e71c3 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 2.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_09780 b606e463fb16f5de943b171fde5e71c3 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 2.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_09780 b606e463fb16f5de943b171fde5e71c3 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 2.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_09780 b606e463fb16f5de943b171fde5e71c3 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 2.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_25880 1d82c2916991d68f18b9f4e74ff5283f 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 7.5E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_25880 1d82c2916991d68f18b9f4e74ff5283f 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 227 241 7.5E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_25880 1d82c2916991d68f18b9f4e74ff5283f 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 7.5E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_25880 1d82c2916991d68f18b9f4e74ff5283f 284 Pfam PF00561 alpha/beta hydrolase fold 25 266 5.9E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_25880 1d82c2916991d68f18b9f4e74ff5283f 284 Gene3D G3DSA:3.40.50.1820 1 282 1.3E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_25880 1d82c2916991d68f18b9f4e74ff5283f 284 SUPERFAMILY SSF53474 3 279 6.77E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.5E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.1E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.1E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 SUPERFAMILY SSF47413 3 59 2.55E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 309 1.4E-31 T 14-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 Gene3D G3DSA:3.40.50.2300 159 288 6.8E-73 T 14-10-2018 C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 SUPERFAMILY SSF53822 60 330 7.07E-72 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 Gene3D G3DSA:3.40.50.2300 65 307 6.8E-73 T 14-10-2018 C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 Gene3D G3DSA:1.10.260.40 3 59 8.9E-23 T 14-10-2018 C2I25_05975 e3a0557fc8ea9fc073e0c6a759353864 337 SMART SM00354 1 71 6.9E-32 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_11705 5c9cf52d7e50878c89925fb4d72b2029 293 Pfam PF00924 Mechanosensitive ion channel 77 274 6.5E-46 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 C2I25_11705 5c9cf52d7e50878c89925fb4d72b2029 293 Gene3D G3DSA:3.30.70.100 185 272 1.2E-22 T 14-10-2018 C2I25_11705 5c9cf52d7e50878c89925fb4d72b2029 293 SUPERFAMILY SSF82861 30 118 3.79E-14 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 C2I25_11705 5c9cf52d7e50878c89925fb4d72b2029 293 SUPERFAMILY SSF82689 186 284 2.88E-17 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 C2I25_11705 5c9cf52d7e50878c89925fb4d72b2029 293 Gene3D G3DSA:2.30.30.60 135 183 1.9E-21 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily C2I25_11705 5c9cf52d7e50878c89925fb4d72b2029 293 SUPERFAMILY SSF50182 120 182 3.92E-15 T 14-10-2018 IPR010920 LSM domain superfamily C2I25_19430 ee7054fa1caa03cca52c500c2647239f 340 Gene3D G3DSA:1.10.260.40 1 60 7.3E-23 T 14-10-2018 C2I25_19430 ee7054fa1caa03cca52c500c2647239f 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.5E-19 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_19430 ee7054fa1caa03cca52c500c2647239f 340 SMART SM00354 2 72 1.7E-29 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_19430 ee7054fa1caa03cca52c500c2647239f 340 SUPERFAMILY SSF53822 61 337 1.18E-74 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_19430 ee7054fa1caa03cca52c500c2647239f 340 Gene3D G3DSA:3.40.50.2300 167 330 1.0E-92 T 14-10-2018 C2I25_19430 ee7054fa1caa03cca52c500c2647239f 340 Gene3D G3DSA:3.40.50.2300 76 328 1.0E-92 T 14-10-2018 C2I25_19430 ee7054fa1caa03cca52c500c2647239f 340 SUPERFAMILY SSF47413 2 60 1.34E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_19430 ee7054fa1caa03cca52c500c2647239f 340 Pfam PF13377 Periplasmic binding protein-like domain 175 336 1.5E-31 T 14-10-2018 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 Pfam PF02222 ATP-grasp domain 115 284 3.6E-61 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 SUPERFAMILY SSF51246 308 376 1.02E-16 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 Gene3D G3DSA:3.40.50.20 1 115 5.0E-50 T 14-10-2018 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 10 359 43.693 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 SUPERFAMILY SSF56059 106 304 2.12E-64 T 14-10-2018 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 361 3.3E-133 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 Gene3D G3DSA:3.30.470.20 185 374 3.4E-85 T 14-10-2018 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 Gene3D G3DSA:3.30.1490.20 116 184 2.3E-29 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 6 74 8.3E-6 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I25_09935 2933ecf3300678697b39316f3e041e0e 383 SUPERFAMILY SSF52440 8 93 5.04E-27 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 Gene3D G3DSA:3.30.300.30 615 718 6.5E-27 T 14-10-2018 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 Gene3D G3DSA:3.40.50.12780 216 613 2.9E-125 T 14-10-2018 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 Pfam PF00550 Phosphopantetheine attachment site 733 793 5.7E-7 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 Pfam PF07993 Male sterility protein 834 1070 3.8E-52 T 14-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 SUPERFAMILY SSF56801 187 744 1.22E-148 T 14-10-2018 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 Pfam PF13193 AMP-binding enzyme C-terminal domain 629 702 1.6E-7 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 Gene3D G3DSA:3.40.50.720 815 1185 6.5E-75 T 14-10-2018 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 244 645 3.8E-126 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 Gene3D G3DSA:3.40.50.1820 721 814 1.2E-19 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 831 1186 5.3E-64 T 14-10-2018 IPR010080 Thioester reductase-like domain C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 ProSitePatterns PS00012 Phosphopantetheine attachment site. 755 770 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 SUPERFAMILY SSF47336 723 793 1.06E-13 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 SUPERFAMILY SSF51735 831 1106 1.89E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 ProSitePatterns PS00455 Putative AMP-binding domain signature. 358 369 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 PIRSF PIRSF001617 587 675 1.3E-17 T 14-10-2018 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 PIRSF PIRSF001617 661 1134 7.3E-54 T 14-10-2018 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 PIRSF PIRSF001617 328 590 7.6E-23 T 14-10-2018 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 PIRSF PIRSF001617 77 341 1.1E-22 T 14-10-2018 C2I25_09410 1af4bff55e9ae68bdf186e15685d87a4 1193 Pfam PF00501 AMP-binding enzyme 225 621 6.3E-98 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 Gene3D G3DSA:3.40.50.200 9 314 4.9E-114 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 52 63 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 SUPERFAMILY SSF52743 29 313 4.45E-85 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 PRINTS PR00723 Subtilisin serine protease family (S8) signature 89 102 2.2E-22 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 PRINTS PR00723 Subtilisin serine protease family (S8) signature 254 270 2.2E-22 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 PRINTS PR00723 Subtilisin serine protease family (S8) signature 47 66 2.2E-22 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 Pfam PF00082 Subtilase family 47 298 1.3E-55 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 93 103 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I25_01615 0a57bbc8426a9752ce5223a41797da9f 315 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 255 265 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 PIRSF PIRSF002599 1 67 4.9E-25 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 SUPERFAMILY SSF50249 2 66 2.03E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 SMART SM00357 4 67 3.3E-32 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 14-10-2018 IPR019844 Cold-shock conserved site C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 PRINTS PR00050 Cold shock protein signature 25 34 1.5E-19 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 PRINTS PR00050 Cold shock protein signature 5 20 1.5E-19 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 PRINTS PR00050 Cold shock protein signature 40 58 1.5E-19 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 Gene3D G3DSA:2.40.50.140 3 67 2.0E-30 T 14-10-2018 C2I25_13280 86d8cca0fb089969f79aa71fd6b63346 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 6.7E-33 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_09020 94d6c24cd91396509ae36b47bf9545ae 301 Gene3D G3DSA:3.40.50.720 2 300 5.2E-72 T 14-10-2018 C2I25_09020 94d6c24cd91396509ae36b47bf9545ae 301 SUPERFAMILY SSF51735 2 288 4.81E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_09020 94d6c24cd91396509ae36b47bf9545ae 301 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 7.3E-18 T 14-10-2018 IPR013549 Domain of unknown function DUF1731 C2I25_09020 94d6c24cd91396509ae36b47bf9545ae 301 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 2.6E-108 T 14-10-2018 IPR010099 Epimerase family protein SDR39U1 C2I25_09020 94d6c24cd91396509ae36b47bf9545ae 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 215 4.0E-18 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_19210 eabc09993c74fb5559915fa9bcebcccc 268 Gene3D G3DSA:3.30.1240.10 82 188 1.4E-55 T 14-10-2018 C2I25_19210 eabc09993c74fb5559915fa9bcebcccc 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 232 1.5E-27 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_19210 eabc09993c74fb5559915fa9bcebcccc 268 Gene3D G3DSA:3.40.50.1000 5 257 1.4E-55 T 14-10-2018 IPR023214 HAD superfamily C2I25_19210 eabc09993c74fb5559915fa9bcebcccc 268 SUPERFAMILY SSF56784 1 258 9.86E-56 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_19210 eabc09993c74fb5559915fa9bcebcccc 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 257 2.3E-51 T 14-10-2018 C2I25_19210 eabc09993c74fb5559915fa9bcebcccc 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 253 9.9E-50 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 13 38 9.6E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 9.6E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 428 9.6E-20 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 356 531 1.2E-42 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 SMART SM00304 223 274 3.1E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 SMART SM00304 519 575 28.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 SMART SM00283 303 578 3.5E-66 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 Gene3D G3DSA:1.10.287.950 270 578 2.3E-67 T 14-10-2018 C2I25_09415 4bcf414851ed9464824212bf55b629fa 580 SUPERFAMILY SSF58104 250 578 3.66E-66 T 14-10-2018 C2I25_12145 c5bfc833cb6ee7aa6b37324605c51e60 301 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 3.0E-148 T 14-10-2018 C2I25_12145 c5bfc833cb6ee7aa6b37324605c51e60 301 SUPERFAMILY SSF52317 17 297 1.24E-104 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_12145 c5bfc833cb6ee7aa6b37324605c51e60 301 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 299 43.374 T 14-10-2018 IPR033752 MetA family C2I25_12145 c5bfc833cb6ee7aa6b37324605c51e60 301 PIRSF PIRSF000450 1 301 6.5E-147 T 14-10-2018 IPR033752 MetA family C2I25_12145 c5bfc833cb6ee7aa6b37324605c51e60 301 Pfam PF04204 Homoserine O-succinyltransferase 2 299 2.0E-141 T 14-10-2018 IPR033752 MetA family C2I25_12145 c5bfc833cb6ee7aa6b37324605c51e60 301 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 4.5E-134 T 14-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 C2I25_12145 c5bfc833cb6ee7aa6b37324605c51e60 301 Gene3D G3DSA:3.40.50.880 1 301 2.3E-129 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_05570 1e83e3dd45f335bbf1a6c1f6feda8f18 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 7.2E-58 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_05570 1e83e3dd45f335bbf1a6c1f6feda8f18 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 263 6.7E-66 T 14-10-2018 C2I25_05570 1e83e3dd45f335bbf1a6c1f6feda8f18 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 14-10-2018 C2I25_05570 1e83e3dd45f335bbf1a6c1f6feda8f18 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 9.1E-29 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_05570 1e83e3dd45f335bbf1a6c1f6feda8f18 269 SUPERFAMILY SSF56784 2 267 3.08E-68 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_05570 1e83e3dd45f335bbf1a6c1f6feda8f18 269 Gene3D G3DSA:3.40.50.1000 6 260 6.8E-63 T 14-10-2018 IPR023214 HAD superfamily C2I25_05570 1e83e3dd45f335bbf1a6c1f6feda8f18 269 Gene3D G3DSA:3.30.1240.10 86 191 6.8E-63 T 14-10-2018 C2I25_05405 4c766bb4df979150ad4dfdc30cb066e2 192 Pfam PF01928 CYTH domain 4 184 7.4E-31 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 C2I25_05405 4c766bb4df979150ad4dfdc30cb066e2 192 PIRSF PIRSF012526 1 191 1.2E-76 T 14-10-2018 IPR009195 Uncharacterised protein family YjbK C2I25_05405 4c766bb4df979150ad4dfdc30cb066e2 192 SUPERFAMILY SSF55154 5 186 2.29E-30 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 C2I25_05405 4c766bb4df979150ad4dfdc30cb066e2 192 SMART SM01118 4 190 2.0E-23 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 C2I25_05405 4c766bb4df979150ad4dfdc30cb066e2 192 Gene3D G3DSA:2.40.320.10 1 176 2.3E-52 T 14-10-2018 C2I25_23360 41ab827691fea8176567241c3ff677b1 144 Pfam PF01047 MarR family 40 93 2.3E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_23360 41ab827691fea8176567241c3ff677b1 144 SMART SM00347 30 129 3.8E-21 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_23360 41ab827691fea8176567241c3ff677b1 144 Gene3D G3DSA:1.10.10.10 2 144 2.6E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23360 41ab827691fea8176567241c3ff677b1 144 SUPERFAMILY SSF46785 7 144 2.23E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 Pfam PF08343 Ribonucleotide reductase N-terminal 3 81 2.9E-20 T 14-10-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 Gene3D G3DSA:1.10.1650.20 278 332 3.3E-189 T 14-10-2018 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 Pfam PF02867 Ribonucleotide reductase, barrel domain 160 678 1.8E-140 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 Gene3D G3DSA:3.20.70.20 144 680 3.3E-189 T 14-10-2018 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 481 504 3.4E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 370 381 3.4E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 235 254 3.4E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 414 437 3.4E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 563 590 3.4E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 453 475 3.4E-30 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 552 574 - T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 3 694 0.0 T 14-10-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 SUPERFAMILY SSF51998 159 683 3.66E-173 T 14-10-2018 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 SUPERFAMILY SSF48168 5 158 4.58E-39 T 14-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 86 682 1.2E-170 T 14-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_04650 52c4ab58086b83b362d0173ce50e6aa6 694 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 84 155 2.1E-13 T 14-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 SUPERFAMILY SSF52777 1054 1231 2.33E-37 T 14-10-2018 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Gene3D G3DSA:3.30.559.10 8 367 4.7E-69 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 SUPERFAMILY SSF52777 1242 1486 3.89E-35 T 14-10-2018 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Gene3D G3DSA:1.10.1200.10 961 1038 1.6E-20 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Gene3D G3DSA:3.30.559.10 1039 1221 7.4E-57 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Pfam PF00668 Condensation domain 1050 1488 2.3E-84 T 14-10-2018 IPR001242 Condensation domain C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Pfam PF00668 Condensation domain 4 436 5.6E-87 T 14-10-2018 IPR001242 Condensation domain C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Gene3D G3DSA:3.40.50.12780 444 860 9.3E-148 T 14-10-2018 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Pfam PF00550 Phosphopantetheine attachment site 974 1033 7.1E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Gene3D G3DSA:3.30.300.30 861 960 1.2E-34 T 14-10-2018 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 SUPERFAMILY SSF52777 9 182 9.45E-24 T 14-10-2018 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Pfam PF00501 AMP-binding enzyme 458 866 2.6E-111 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 945 6.7E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 SUPERFAMILY SSF56801 414 984 1.83E-169 T 14-10-2018 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 SUPERFAMILY SSF52777 188 421 7.23E-34 T 14-10-2018 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 SUPERFAMILY SSF47336 965 1033 7.49E-17 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 ProSitePatterns PS00455 Putative AMP-binding domain signature. 601 612 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Gene3D G3DSA:3.30.559.30 1222 1488 1.9E-59 T 14-10-2018 C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1363 1508 8.6E-31 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 479 890 8.5E-144 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_27415 94713bb0928dfea6ca98b7c72f770fed 1518 Gene3D G3DSA:3.30.559.30 186 423 4.7E-69 T 14-10-2018 C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 173 185 6.5E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 205 217 6.5E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 82 95 6.5E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 120 6.5E-21 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 Hamap MF_01974 Methionine aminopeptidase [map]. 17 264 35.774 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 SUPERFAMILY SSF55920 14 262 3.01E-70 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 Gene3D G3DSA:3.90.230.10 17 264 1.2E-85 T 14-10-2018 C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 17 263 8.6E-90 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_12385 b9da8b1ef6cd1882d6d974755ba5a761 264 Pfam PF00557 Metallopeptidase family M24 27 254 3.0E-47 T 14-10-2018 IPR000994 Peptidase M24 C2I25_17290 c38cfe63e27123f50d7b250c88b9f0a1 381 Gene3D G3DSA:1.10.260.50 15 278 1.0E-142 T 14-10-2018 C2I25_17290 c38cfe63e27123f50d7b250c88b9f0a1 381 Gene3D G3DSA:3.90.1150.10 4 368 1.0E-142 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_17290 c38cfe63e27123f50d7b250c88b9f0a1 381 Pfam PF00266 Aminotransferase class-V 4 366 3.0E-84 T 14-10-2018 IPR000192 Aminotransferase class V domain C2I25_17290 c38cfe63e27123f50d7b250c88b9f0a1 381 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site C2I25_17290 c38cfe63e27123f50d7b250c88b9f0a1 381 PIRSF PIRSF005572 1 381 5.4E-125 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I25_17290 c38cfe63e27123f50d7b250c88b9f0a1 381 Gene3D G3DSA:3.40.640.10 61 235 1.0E-142 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_17290 c38cfe63e27123f50d7b250c88b9f0a1 381 SUPERFAMILY SSF53383 3 374 6.05E-105 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_22515 b10818d2ef3e23278259dd9589c04501 428 Pfam PF03063 Prismane/CO dehydrogenase family 1 79 3.7E-14 T 14-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 C2I25_22515 b10818d2ef3e23278259dd9589c04501 428 Gene3D G3DSA:1.20.1270.20 27 111 6.5E-30 T 14-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 C2I25_22515 b10818d2ef3e23278259dd9589c04501 428 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 428 16.57 T 14-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 C2I25_22515 b10818d2ef3e23278259dd9589c04501 428 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 23 427 4.6E-170 T 14-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 C2I25_22515 b10818d2ef3e23278259dd9589c04501 428 Gene3D G3DSA:3.40.50.2030 257 427 2.0E-56 T 14-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 C2I25_22515 b10818d2ef3e23278259dd9589c04501 428 SUPERFAMILY SSF56821 1 427 1.26E-149 T 14-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 C2I25_22515 b10818d2ef3e23278259dd9589c04501 428 Gene3D G3DSA:3.40.50.2030 113 256 5.3E-60 T 14-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 C2I25_22515 b10818d2ef3e23278259dd9589c04501 428 Pfam PF03063 Prismane/CO dehydrogenase family 80 423 1.3E-104 T 14-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 C2I25_13870 b443aca10d30c0db82fb77eb46cd9f48 105 Pfam PF01883 Iron-sulfur cluster assembly protein 10 82 5.7E-18 T 14-10-2018 IPR002744 MIP18 family-like C2I25_13870 b443aca10d30c0db82fb77eb46cd9f48 105 Gene3D G3DSA:3.30.300.130 1 105 5.8E-38 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I25_13870 b443aca10d30c0db82fb77eb46cd9f48 105 SUPERFAMILY SSF117916 4 102 5.23E-30 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.011 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 SUPERFAMILY SSF53254 1 230 7.24E-74 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 233 2.6E-108 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 PIRSF PIRSF000709 3 116 6.8E-7 T 14-10-2018 C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 PIRSF PIRSF000709 172 232 0.52 T 14-10-2018 C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 123 4.6E-29 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 SMART SM00855 3 189 8.2E-27 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_27540 9044ed1cf3dfd13817c31e2aab696c57 245 Gene3D G3DSA:3.40.50.1240 1 237 1.5E-84 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_19865 ff14200fa16adeb944030e3317c42e0c 345 Pfam PF13180 PDZ domain 127 194 1.8E-13 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_19865 ff14200fa16adeb944030e3317c42e0c 345 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 233 332 1.0E-11 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 C2I25_19865 ff14200fa16adeb944030e3317c42e0c 345 SUPERFAMILY SSF54211 229 334 1.1E-23 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_19865 ff14200fa16adeb944030e3317c42e0c 345 Gene3D G3DSA:3.30.230.10 218 345 3.0E-21 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_19865 ff14200fa16adeb944030e3317c42e0c 345 SMART SM00228 120 187 0.0038 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_19865 ff14200fa16adeb944030e3317c42e0c 345 Gene3D G3DSA:2.30.42.10 123 217 3.3E-25 T 14-10-2018 C2I25_19865 ff14200fa16adeb944030e3317c42e0c 345 SUPERFAMILY SSF50156 128 214 2.23E-15 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I25_23785 cbee05399718483c0b908024dd760f1a 298 Pfam PF00892 EamA-like transporter family 6 135 1.1E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_23785 cbee05399718483c0b908024dd760f1a 298 Pfam PF00892 EamA-like transporter family 144 276 1.8E-23 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_23785 cbee05399718483c0b908024dd760f1a 298 SUPERFAMILY SSF103481 39 138 1.12E-10 T 14-10-2018 C2I25_23785 cbee05399718483c0b908024dd760f1a 298 SUPERFAMILY SSF103481 186 277 2.75E-17 T 14-10-2018 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Gene3D G3DSA:1.10.150.20 85 150 1.9E-19 T 14-10-2018 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SMART SM00481 338 417 1.5E-21 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 PIRSF PIRSF005047 3 572 2.3E-242 T 14-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SUPERFAMILY SSF81301 154 316 2.16E-45 T 14-10-2018 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SUPERFAMILY SSF47802 2 79 7.19E-20 T 14-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SMART SM00278 90 109 56.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SMART SM00278 50 69 5.8 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SMART SM00278 125 144 6.8 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Gene3D G3DSA:3.20.20.140 327 572 1.6E-78 T 14-10-2018 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Pfam PF14791 DNA polymerase beta thumb 255 316 1.8E-19 T 14-10-2018 IPR029398 DNA polymerase beta, thumb domain C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SMART SM00483 2 316 6.3E-86 T 14-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Pfam PF02811 PHP domain 339 466 3.9E-10 T 14-10-2018 IPR004013 PHP domain GO:0003824 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Gene3D G3DSA:1.10.150.110 1 84 1.4E-19 T 14-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SUPERFAMILY SSF89550 338 567 9.29E-57 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Pfam PF14716 Helix-hairpin-helix domain 6 71 8.7E-20 T 14-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Gene3D G3DSA:3.30.460.10 154 260 1.4E-22 T 14-10-2018 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Pfam PF14520 Helix-hairpin-helix domain 92 145 2.5E-6 T 14-10-2018 C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 Gene3D G3DSA:3.30.210.10 261 326 1.1E-18 T 14-10-2018 IPR037160 DNA polymerase, thumb domain superfamily C2I25_16550 46f94d435363fb298d740d7a05c56e44 572 SUPERFAMILY SSF158702 48 145 1.78E-8 T 14-10-2018 C2I25_17585 ac62bb7657d7a5369f687a66c3ff6322 262 Pfam PF02666 Phosphatidylserine decarboxylase 59 256 5.1E-58 T 14-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 C2I25_17585 ac62bb7657d7a5369f687a66c3ff6322 262 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 257 4.7E-52 T 14-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 C2I25_17585 ac62bb7657d7a5369f687a66c3ff6322 262 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 259 40.52 T 14-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.5E-94 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 SMART SM00322 59 124 3.2E-7 T 14-10-2018 IPR004087 K Homology domain GO:0003676 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 SUPERFAMILY SSF54821 107 205 2.88E-37 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 3.6E-39 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 SUPERFAMILY SSF54814 2 105 1.33E-37 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 Pfam PF07650 KH domain 37 109 2.0E-20 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 Gene3D G3DSA:3.30.300.20 17 106 6.4E-32 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 Gene3D G3DSA:3.30.1140.32 107 207 2.4E-39 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10940 122c52b97e2cada8071572a9d4cae8d9 219 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.365 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 C2I25_26540 c43cfce7ac22ac06e38a3b4c9d036a47 141 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 13 137 2.4E-31 T 14-10-2018 IPR006480 Bacteriophage holin family C2I25_26540 c43cfce7ac22ac06e38a3b4c9d036a47 141 Pfam PF05105 Bacteriophage holin family 18 127 6.8E-40 T 14-10-2018 IPR006480 Bacteriophage holin family C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.8E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.8E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 Gene3D G3DSA:3.40.50.2300 162 284 3.6E-66 T 14-10-2018 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 Gene3D G3DSA:1.10.260.40 4 60 2.7E-17 T 14-10-2018 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 Pfam PF13377 Periplasmic binding protein-like domain 169 325 3.0E-28 T 14-10-2018 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 SMART SM00354 2 71 2.3E-28 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 Gene3D G3DSA:3.40.50.2300 65 306 3.6E-66 T 14-10-2018 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 SUPERFAMILY SSF47413 3 59 1.63E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 1.4E-15 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_07550 9e104ca63bce550a2b8da8119211ed77 328 SUPERFAMILY SSF53822 59 311 2.67E-63 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_17110 24ce035a051fc7ffdb73d85ba03ec4eb 215 SUPERFAMILY SSF50800 5 213 1.41E-67 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily C2I25_17110 24ce035a051fc7ffdb73d85ba03ec4eb 215 Gene3D G3DSA:2.40.33.20 2 215 1.2E-68 T 14-10-2018 C2I25_17110 24ce035a051fc7ffdb73d85ba03ec4eb 215 Pfam PF03475 3-alpha domain 171 213 2.6E-12 T 14-10-2018 IPR005163 3-alpha domain C2I25_17110 24ce035a051fc7ffdb73d85ba03ec4eb 215 Pfam PF03473 MOSC domain 50 161 1.3E-20 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 C2I25_21265 01c2faa51d3be41b7659c0e4aa0bc5f3 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 2.7E-34 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_21265 01c2faa51d3be41b7659c0e4aa0bc5f3 312 SUPERFAMILY SSF54593 5 278 1.32E-46 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21265 01c2faa51d3be41b7659c0e4aa0bc5f3 312 Gene3D G3DSA:3.10.180.10 7 303 4.8E-123 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21265 01c2faa51d3be41b7659c0e4aa0bc5f3 312 Gene3D G3DSA:3.10.180.10 67 210 4.8E-123 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_12690 4cbea32544d84444e4d7792948b3bc7f 415 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 296 409 3.5E-37 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12690 4cbea32544d84444e4d7792948b3bc7f 415 SUPERFAMILY SSF143243 266 412 1.27E-41 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12690 4cbea32544d84444e4d7792948b3bc7f 415 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 294 409 1.8E-40 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12690 4cbea32544d84444e4d7792948b3bc7f 415 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 346 401 1.0E-26 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12690 4cbea32544d84444e4d7792948b3bc7f 415 Gene3D G3DSA:3.30.460.80 242 392 2.1E-35 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_15005 1786ef014e2618df072e930f953badc3 231 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_15005 1786ef014e2618df072e930f953badc3 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 4.9E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_15005 1786ef014e2618df072e930f953badc3 231 SMART SM00448 2 112 1.7E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_15005 1786ef014e2618df072e930f953badc3 231 Gene3D G3DSA:3.40.50.2300 2 121 3.9E-32 T 14-10-2018 C2I25_15005 1786ef014e2618df072e930f953badc3 231 Gene3D G3DSA:1.10.10.10 124 228 6.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15005 1786ef014e2618df072e930f953badc3 231 SMART SM00862 149 225 5.6E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_15005 1786ef014e2618df072e930f953badc3 231 SUPERFAMILY SSF46894 128 227 1.25E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_15005 1786ef014e2618df072e930f953badc3 231 SUPERFAMILY SSF52172 1 123 6.83E-35 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_05850 05a778cbe64ab324fa087ae39edc642b 325 Gene3D G3DSA:1.10.3210.10 2 258 3.6E-42 T 14-10-2018 C2I25_05850 05a778cbe64ab324fa087ae39edc642b 325 Pfam PF01966 HD domain 49 116 5.5E-9 T 14-10-2018 IPR006674 HD domain C2I25_05850 05a778cbe64ab324fa087ae39edc642b 325 SUPERFAMILY SSF109604 3 259 6.87E-48 T 14-10-2018 C2I25_05850 05a778cbe64ab324fa087ae39edc642b 325 SMART SM00471 45 159 5.7E-8 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_22655 04769c84eea7dfc87785a6a2c38b99cc 167 SUPERFAMILY SSF52833 65 154 1.52E-5 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_22655 04769c84eea7dfc87785a6a2c38b99cc 167 Gene3D G3DSA:3.40.30.10 39 167 1.2E-5 T 14-10-2018 C2I25_19255 2131219789ccfaf1a53eb179110840c0 371 Pfam PF00144 Beta-lactamase 72 354 3.1E-56 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_19255 2131219789ccfaf1a53eb179110840c0 371 SUPERFAMILY SSF56601 54 358 1.23E-75 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_19255 2131219789ccfaf1a53eb179110840c0 371 Gene3D G3DSA:3.40.710.10 55 359 2.2E-78 T 14-10-2018 C2I25_20185 135ad44ac1a4340184fffb5e7dc0e541 362 SUPERFAMILY SSF102114 102 320 9.42E-14 T 14-10-2018 C2I25_20185 135ad44ac1a4340184fffb5e7dc0e541 362 Pfam PF04055 Radical SAM superfamily 119 289 1.7E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_20185 135ad44ac1a4340184fffb5e7dc0e541 362 Gene3D G3DSA:1.10.150.530 1 77 4.6E-21 T 14-10-2018 C2I25_20185 135ad44ac1a4340184fffb5e7dc0e541 362 PIRSF PIRSF006004 8 362 1.1E-134 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 C2I25_20185 135ad44ac1a4340184fffb5e7dc0e541 362 Gene3D G3DSA:3.20.20.70 80 343 1.3E-98 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_20185 135ad44ac1a4340184fffb5e7dc0e541 362 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 13 362 2.3E-159 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 C2I25_20185 135ad44ac1a4340184fffb5e7dc0e541 362 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 16 358 71.209 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 C2I25_20185 135ad44ac1a4340184fffb5e7dc0e541 362 Pfam PF13394 4Fe-4S single cluster domain 124 217 7.9E-5 T 14-10-2018 C2I25_01085 14609ced81adb950a65a23a66157f016 323 Pfam PF00753 Metallo-beta-lactamase superfamily 32 228 2.9E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_01085 14609ced81adb950a65a23a66157f016 323 SUPERFAMILY SSF56281 4 270 7.34E-46 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_01085 14609ced81adb950a65a23a66157f016 323 Gene3D G3DSA:3.60.15.10 8 270 9.3E-54 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_01085 14609ced81adb950a65a23a66157f016 323 SMART SM00849 24 228 1.8E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_03835 33cbe30bc5ee98dc4b9705015d885bab 237 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 36.486 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 C2I25_03835 33cbe30bc5ee98dc4b9705015d885bab 237 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I25_03835 33cbe30bc5ee98dc4b9705015d885bab 237 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I25_03835 33cbe30bc5ee98dc4b9705015d885bab 237 SUPERFAMILY SSF53335 3 229 2.74E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_03835 33cbe30bc5ee98dc4b9705015d885bab 237 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 2.6E-135 T 14-10-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I25_03835 33cbe30bc5ee98dc4b9705015d885bab 237 Gene3D G3DSA:3.40.50.150 15 234 2.6E-66 T 14-10-2018 C2I25_03835 33cbe30bc5ee98dc4b9705015d885bab 237 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 1.6E-102 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 C2I25_03835 33cbe30bc5ee98dc4b9705015d885bab 237 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 3.5E-81 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 C2I25_22065 769cc91105273eeadb44976adfd58772 497 PIRSF PIRSF005690 11 496 8.0E-167 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_22065 769cc91105273eeadb44976adfd58772 497 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 30 484 2.6E-166 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_22740 36876d10d9dcf7911bbe1d29430a56bd 131 Gene3D G3DSA:3.40.30.10 1 120 4.1E-44 T 14-10-2018 C2I25_22740 36876d10d9dcf7911bbe1d29430a56bd 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 114 9.4E-36 T 14-10-2018 IPR006504 Transcriptional regulator Spx/MgsR C2I25_22740 36876d10d9dcf7911bbe1d29430a56bd 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.128 T 14-10-2018 IPR023731 Regulatory protein Spx GO:0045892 C2I25_22740 36876d10d9dcf7911bbe1d29430a56bd 131 SUPERFAMILY SSF52833 1 125 3.79E-38 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_22740 36876d10d9dcf7911bbe1d29430a56bd 131 Pfam PF03960 ArsC family 31 113 6.1E-22 T 14-10-2018 IPR006660 Arsenate reductase-like C2I25_00110 51f0e98ee7fec01ec2d7593465c0a612 452 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 8 451 6.4E-156 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_00110 51f0e98ee7fec01ec2d7593465c0a612 452 PIRSF PIRSF002746 2 452 3.2E-157 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_00110 51f0e98ee7fec01ec2d7593465c0a612 452 Pfam PF02447 GntP family permease 5 449 8.6E-167 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_10845 5a5ac4b79e6fbc309aa47345e607ddff 121 Gene3D G3DSA:1.10.8.50 1 71 9.5E-29 T 14-10-2018 C2I25_10845 5a5ac4b79e6fbc309aa47345e607ddff 121 SUPERFAMILY SSF46946 2 120 1.44E-44 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 C2I25_10845 5a5ac4b79e6fbc309aa47345e607ddff 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.4E-32 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10845 5a5ac4b79e6fbc309aa47345e607ddff 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.473 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10845 5a5ac4b79e6fbc309aa47345e607ddff 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10845 5a5ac4b79e6fbc309aa47345e607ddff 121 PIRSF PIRSF002134 1 121 5.2E-42 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10845 5a5ac4b79e6fbc309aa47345e607ddff 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.3E-52 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10845 5a5ac4b79e6fbc309aa47345e607ddff 121 Gene3D G3DSA:4.10.910.10 72 121 6.3E-25 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 PRINTS PR00944 Copper ion binding protein signature 15 28 1.4E-5 T 14-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 PRINTS PR00944 Copper ion binding protein signature 54 67 1.4E-5 T 14-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 PRINTS PR00944 Copper ion binding protein signature 28 41 1.4E-5 T 14-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 PRINTS PR00944 Copper ion binding protein signature 3 15 1.4E-5 T 14-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 SUPERFAMILY SSF55008 1 67 8.9E-22 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 67 1.9E-22 T 14-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 Gene3D G3DSA:3.30.70.100 1 68 6.2E-29 T 14-10-2018 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I25_20870 21c47d6e30df539b813b08aecc0f20a1 68 Pfam PF00403 Heavy-metal-associated domain 5 66 1.8E-19 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I25_09240 1df215d8822efba2626bb8b18783d7cf 316 SUPERFAMILY SSF103481 210 305 1.96E-11 T 14-10-2018 C2I25_09240 1df215d8822efba2626bb8b18783d7cf 316 SUPERFAMILY SSF103481 54 157 9.29E-13 T 14-10-2018 C2I25_09240 1df215d8822efba2626bb8b18783d7cf 316 Pfam PF00892 EamA-like transporter family 15 154 1.8E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_09240 1df215d8822efba2626bb8b18783d7cf 316 Pfam PF00892 EamA-like transporter family 167 301 2.6E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_23140 e0e5f53932cec44a5d5c4f1ab52d2a2c 165 Gene3D G3DSA:1.20.120.450 25 153 8.2E-10 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_23140 e0e5f53932cec44a5d5c4f1ab52d2a2c 165 SUPERFAMILY SSF109854 28 152 1.63E-14 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_23140 e0e5f53932cec44a5d5c4f1ab52d2a2c 165 Pfam PF12867 DinB superfamily 35 146 1.5E-6 T 14-10-2018 IPR024775 DinB-like domain C2I25_04340 89ad13d64d8f45542a32f8b46a8b6da3 338 SUPERFAMILY SSF89550 63 330 1.44E-34 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I25_04340 89ad13d64d8f45542a32f8b46a8b6da3 338 Gene3D G3DSA:3.20.20.140 56 333 6.2E-58 T 14-10-2018 C2I25_04340 89ad13d64d8f45542a32f8b46a8b6da3 338 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 60 301 3.2E-28 T 14-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 SUPERFAMILY SSF47384 221 304 5.3E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 SUPERFAMILY SSF55874 294 457 1.26E-46 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 Gene3D G3DSA:3.30.565.10 309 463 4.7E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 SMART SM00387 349 461 4.5E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 303 2.5E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 Pfam PF00672 HAMP domain 187 233 2.2E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 SMART SM00388 238 304 2.9E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 SUPERFAMILY SSF158472 186 233 1.29E-11 T 14-10-2018 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 Gene3D G3DSA:1.10.287.130 234 304 2.0E-23 T 14-10-2018 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 458 3.2E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 3.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 3.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 3.0E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 Gene3D G3DSA:1.10.8.500 186 233 3.0E-10 T 14-10-2018 C2I25_04915 ff7f6e836ed9e76fabc98d4dd476eed9 466 SMART SM00304 185 237 5.4E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 Gene3D G3DSA:3.20.20.60 10 336 5.5E-130 T 14-10-2018 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 SUPERFAMILY SSF51621 9 334 4.89E-84 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 SUPERFAMILY SSF50800 69 164 5.58E-26 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 Gene3D G3DSA:2.40.33.10 70 164 5.5E-130 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 PRINTS PR01050 Pyruvate kinase family signature 266 290 3.0E-56 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 PRINTS PR01050 Pyruvate kinase family signature 58 74 3.0E-56 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 PRINTS PR01050 Pyruvate kinase family signature 310 326 3.0E-56 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 PRINTS PR01050 Pyruvate kinase family signature 214 240 3.0E-56 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 PRINTS PR01050 Pyruvate kinase family signature 183 197 3.0E-56 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 PRINTS PR01050 Pyruvate kinase family signature 291 309 3.0E-56 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 PRINTS PR01050 Pyruvate kinase family signature 241 265 3.0E-56 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 Pfam PF00224 Pyruvate kinase, barrel domain 10 334 5.7E-114 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_23195 19512de3dcdf29800dbc4f738ea5c615 356 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 10 337 1.2E-132 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_26595 3c179bfb6a35322d39910fa428372f54 209 Pfam PF00574 Clp protease 27 159 9.9E-30 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA C2I25_26595 3c179bfb6a35322d39910fa428372f54 209 PRINTS PR00127 Clp protease catalytic subunit P signature 136 155 2.2E-9 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_26595 3c179bfb6a35322d39910fa428372f54 209 PRINTS PR00127 Clp protease catalytic subunit P signature 29 49 2.2E-9 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_26595 3c179bfb6a35322d39910fa428372f54 209 PRINTS PR00127 Clp protease catalytic subunit P signature 60 77 2.2E-9 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_26595 3c179bfb6a35322d39910fa428372f54 209 SUPERFAMILY SSF52096 14 162 2.53E-41 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_26595 3c179bfb6a35322d39910fa428372f54 209 Gene3D G3DSA:3.90.226.10 8 168 6.4E-45 T 14-10-2018 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 Pfam PF06463 Molybdenum Cofactor Synthesis C 189 316 1.1E-38 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 337 40.818 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 SUPERFAMILY SSF102114 7 304 6.93E-84 T 14-10-2018 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 SMART SM00729 14 222 6.4E-16 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 337 8.5E-120 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 Pfam PF13353 4Fe-4S single cluster domain 21 106 4.1E-7 T 14-10-2018 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 Gene3D G3DSA:3.20.20.70 2 337 6.3E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_15625 fd72580e674a83281e3192cd1fe13647 337 Pfam PF04055 Radical SAM superfamily 19 180 1.5E-30 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 SUPERFAMILY SSF51735 3 246 6.67E-94 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 2.2E-5 T 14-10-2018 C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 Gene3D G3DSA:3.40.50.720 1 246 9.6E-93 T 14-10-2018 C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 2.0E-71 T 14-10-2018 C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20255 aaa988bb8e2a3beb679c6d66694bfbe6 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 2.1E-107 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 PIRSF PIRSF000149 1 334 1.3E-137 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 8.9E-42 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 8.9E-42 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 8.9E-42 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 8.9E-42 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 8.9E-42 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 7.8E-135 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 SMART SM00846 2 151 8.6E-86 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 101 4.7E-38 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 SUPERFAMILY SSF51735 3 167 8.95E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 SUPERFAMILY SSF55347 151 313 5.95E-73 T 14-10-2018 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 Gene3D G3DSA:3.40.50.720 3 327 3.8E-152 T 14-10-2018 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 Gene3D G3DSA:3.30.360.10 150 314 3.8E-152 T 14-10-2018 C2I25_16390 868077dd60fd27a975acbdb3904887ff 342 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 9.0E-69 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Gene3D G3DSA:3.40.50.800 543 645 2.4E-34 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Pfam PF03129 Anticodon binding domain 551 640 2.9E-25 T 14-10-2018 IPR004154 Anticodon-binding C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 223 3.1E-16 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 642 4.0E-239 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Gene3D G3DSA:3.10.20.30 3 65 2.8E-25 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 SMART SM00863 174 223 1.2E-25 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Gene3D G3DSA:3.30.980.10 73 226 1.9E-62 T 14-10-2018 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 474 502 1.7E-47 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 335 363 1.7E-47 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 517 530 1.7E-47 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 368 391 1.7E-47 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 544 556 1.7E-47 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 SUPERFAMILY SSF81271 5 64 9.16E-17 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 SUPERFAMILY SSF52954 537 640 3.93E-32 T 14-10-2018 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Pfam PF02824 TGS domain 5 64 1.5E-11 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 328 539 9.7E-35 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Gene3D G3DSA:3.30.930.10 229 542 2.2E-116 T 14-10-2018 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Gene3D G3DSA:3.30.54.20 135 191 1.9E-62 T 14-10-2018 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 645 35.225 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 SUPERFAMILY SSF55681 247 536 2.28E-95 T 14-10-2018 C2I25_16430 b8da5a4d24da5762806259d0fb1bae29 645 SUPERFAMILY SSF55186 66 245 3.92E-64 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 C2I25_23265 5cf2b3bd1d44bddcfda18dbf88b06682 638 Gene3D G3DSA:3.10.20.490 32 132 1.2E-14 T 14-10-2018 C2I25_23265 5cf2b3bd1d44bddcfda18dbf88b06682 638 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 604 636 3.9E-4 T 14-10-2018 C2I25_23265 5cf2b3bd1d44bddcfda18dbf88b06682 638 Pfam PF14478 Domain of unknown function (DUF4430) 60 129 1.2E-16 T 14-10-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 C2I25_23265 5cf2b3bd1d44bddcfda18dbf88b06682 638 SUPERFAMILY SSF48239 351 526 1.08E-26 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid C2I25_23265 5cf2b3bd1d44bddcfda18dbf88b06682 638 Gene3D G3DSA:1.50.10.20 260 538 7.7E-24 T 14-10-2018 C2I25_02005 329b95fd4a80e5c178cd3a89210a6ef4 536 Gene3D G3DSA:3.90.1300.10 24 536 7.8E-211 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_02005 329b95fd4a80e5c178cd3a89210a6ef4 536 Pfam PF01425 Amidase 89 517 9.6E-77 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_02005 329b95fd4a80e5c178cd3a89210a6ef4 536 SUPERFAMILY SSF75304 67 532 1.57E-95 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_27255 fd8bcf5b1c79ba6c7ac1584a5c066444 155 PIRSF PIRSF021320 2 154 1.6E-47 T 14-10-2018 IPR009326 Protein of unknown function DUF984 C2I25_27255 fd8bcf5b1c79ba6c7ac1584a5c066444 155 SMART SM01022 27 151 6.1E-32 T 14-10-2018 IPR007374 ASCH domain C2I25_27255 fd8bcf5b1c79ba6c7ac1584a5c066444 155 SUPERFAMILY SSF88697 4 151 2.98E-50 T 14-10-2018 IPR015947 PUA-like superfamily C2I25_27255 fd8bcf5b1c79ba6c7ac1584a5c066444 155 Gene3D G3DSA:3.10.400.10 2 155 1.5E-57 T 14-10-2018 C2I25_27255 fd8bcf5b1c79ba6c7ac1584a5c066444 155 Pfam PF04266 ASCH domain 36 150 1.0E-21 T 14-10-2018 IPR007374 ASCH domain C2I25_06925 283ba96dcf1383aa401cc0adcb7d754c 262 Gene3D G3DSA:1.10.12.10 205 262 5.5E-19 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I25_06925 283ba96dcf1383aa401cc0adcb7d754c 262 SUPERFAMILY SSF52096 6 261 9.27E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_06925 283ba96dcf1383aa401cc0adcb7d754c 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 6.1E-50 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I25_06925 283ba96dcf1383aa401cc0adcb7d754c 262 Gene3D G3DSA:3.90.226.10 2 200 1.9E-51 T 14-10-2018 C2I25_01455 f45b907d197e5707a221dca3598c0ae0 203 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 C2I25_01455 f45b907d197e5707a221dca3598c0ae0 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 198 9.8E-60 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_01455 f45b907d197e5707a221dca3598c0ae0 203 PIRSF PIRSF000709 1 175 1.0E-23 T 14-10-2018 C2I25_01455 f45b907d197e5707a221dca3598c0ae0 203 SMART SM00855 4 158 2.7E-19 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_01455 f45b907d197e5707a221dca3598c0ae0 203 Gene3D G3DSA:3.40.50.1240 2 203 2.3E-67 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_01455 f45b907d197e5707a221dca3598c0ae0 203 SUPERFAMILY SSF53254 1 202 6.55E-60 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 Gene3D G3DSA:3.40.47.10 256 400 5.1E-56 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 SMART SM00825 Beta-ketoacyl synthase 6 412 9.5E-16 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 4.5E-198 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 PIRSF PIRSF000447 1 412 2.5E-183 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 Gene3D G3DSA:3.40.47.10 1 254 4.2E-105 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 SUPERFAMILY SSF53901 4 251 3.84E-77 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 9.3E-40 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 5.6E-62 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal C2I25_05525 9a7085a5d7ec7d35c4f794c277beded5 412 SUPERFAMILY SSF53901 214 411 6.11E-77 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_16700 8efe031aa2ef0ee16c97fea5fa81060e 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 3.3E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16700 8efe031aa2ef0ee16c97fea5fa81060e 195 Pfam PF08359 YsiA-like protein, C-terminal region 58 189 1.9E-61 T 14-10-2018 IPR013570 Transcription regulator YsiA, C-terminal C2I25_16700 8efe031aa2ef0ee16c97fea5fa81060e 195 Gene3D G3DSA:1.10.10.60 1 49 3.4E-23 T 14-10-2018 C2I25_16700 8efe031aa2ef0ee16c97fea5fa81060e 195 SUPERFAMILY SSF46689 5 80 1.64E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_16700 8efe031aa2ef0ee16c97fea5fa81060e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.0E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16700 8efe031aa2ef0ee16c97fea5fa81060e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.0E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16700 8efe031aa2ef0ee16c97fea5fa81060e 195 SUPERFAMILY SSF48498 78 189 7.51E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_16700 8efe031aa2ef0ee16c97fea5fa81060e 195 Gene3D G3DSA:1.10.357.10 50 191 1.4E-33 T 14-10-2018 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 SUPERFAMILY SSF46689 174 225 2.96E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 258 7.0E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 274 7.0E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 Pfam PF12833 Helix-turn-helix domain 197 275 3.1E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 SUPERFAMILY SSF46689 228 278 6.27E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 Gene3D G3DSA:1.10.10.60 171 224 5.1E-13 T 14-10-2018 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 228 270 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 SMART SM00342 191 274 6.4E-30 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_27010 f3c2ae2d4a68330af9eac9ce26f6e617 280 Gene3D G3DSA:1.10.10.60 225 278 1.6E-17 T 14-10-2018 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Pfam PF13181 Tetratricopeptide repeat 914 943 9.4E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SUPERFAMILY SSF48452 732 980 5.81E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Gene3D G3DSA:1.25.40.10 513 823 5.9E-38 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Gene3D G3DSA:1.25.40.10 824 1123 5.9E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SUPERFAMILY SSF48452 123 246 3.5E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Gene3D G3DSA:1.25.40.10 71 180 4.2E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SUPERFAMILY SSF48452 563 714 6.01E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Pfam PF09295 ChAPs (Chs5p-Arf1p-binding proteins) 1191 1312 2.4E-4 T 14-10-2018 IPR015374 Chs5p-Arf1p binding C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Pfam PF13432 Tetratricopeptide repeat 635 697 7.6E-4 T 14-10-2018 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Pfam PF13432 Tetratricopeptide repeat 738 786 0.013 T 14-10-2018 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 664 697 15.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 189 222 410.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 1011 1044 180.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 123 156 100.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 912 944 0.13 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 1245 1278 270.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 1279 1312 0.048 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 733 766 0.23 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 1313 1346 47.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 563 596 49.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 878 911 21.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 1347 1380 160.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 767 803 310.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SMART SM00028 597 630 14.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SUPERFAMILY SSF48452 1016 1208 2.96E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 SUPERFAMILY SSF48452 1212 1378 4.32E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Gene3D G3DSA:1.25.40.10 192 300 3.5E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Gene3D G3DSA:1.25.40.10 1274 1384 9.1E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Gene3D G3DSA:1.25.40.10 1142 1273 9.7E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Pfam PF13529 Peptidase_C39 like family 312 418 1.3E-15 T 14-10-2018 IPR039564 Peptidase C39-like C2I25_00490 7271bdf7c2b0af326f7220a296dae7ec 1400 Gene3D G3DSA:3.90.70.10 315 454 2.4E-13 T 14-10-2018 C2I25_18905 81d3e7dd146dd39cd789193c54321f35 88 PIRSF PIRSF037158 1 88 4.5E-61 T 14-10-2018 IPR017122 Uncharacterised conserved protein UCP037158 C2I25_18905 81d3e7dd146dd39cd789193c54321f35 88 Gene3D G3DSA:3.40.5.90 22 84 1.1E-13 T 14-10-2018 C2I25_18905 81d3e7dd146dd39cd789193c54321f35 88 Pfam PF09360 Iron-binding zinc finger CDGSH type 31 75 1.0E-16 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 C2I25_18905 81d3e7dd146dd39cd789193c54321f35 88 SMART SM00704 35 80 0.0016 T 14-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 SUPERFAMILY SSF52540 15 571 8.78E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13395 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:3.30.190.20 134 243 4.9E-256 T 14-10-2018 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:1.10.8.280 288 405 4.9E-256 T 14-10-2018 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:1.20.1580.10 94 494 4.9E-256 T 14-10-2018 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:3.40.50.300 9 597 4.9E-256 T 14-10-2018 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:1.20.1580.10 693 830 5.8E-146 T 14-10-2018 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 Pfam PF00005 ABC transporter 624 860 1.5E-9 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 Hamap MF_00205 UvrABC system protein A [uvrA]. 5 940 23.5 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 SUPERFAMILY SSF52540 619 909 2.6E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13395 e1d6d281091f35459bdb886428c84725 958 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 8 924 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 C2I25_13395 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:3.40.50.300 615 936 5.8E-146 T 14-10-2018 C2I25_18400 76a3ad343f9c051302708639db145614 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 3.6E-81 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_18400 76a3ad343f9c051302708639db145614 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 1.9E-240 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 C2I25_18400 76a3ad343f9c051302708639db145614 450 Gene3D G3DSA:3.30.470.130 1 450 1.4E-201 T 14-10-2018 C2I25_18400 76a3ad343f9c051302708639db145614 450 Pfam PF02785 Biotin carboxylase C-terminal domain 337 444 7.5E-45 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_18400 76a3ad343f9c051302708639db145614 450 SUPERFAMILY SSF52440 1 113 2.59E-51 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_18400 76a3ad343f9c051302708639db145614 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.0E-47 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_18400 76a3ad343f9c051302708639db145614 450 SUPERFAMILY SSF51246 332 445 1.73E-48 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I25_18400 76a3ad343f9c051302708639db145614 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_18400 76a3ad343f9c051302708639db145614 450 SUPERFAMILY SSF56059 83 349 4.24E-67 T 14-10-2018 C2I25_18400 76a3ad343f9c051302708639db145614 450 SMART SM00878 337 443 2.6E-72 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_18400 76a3ad343f9c051302708639db145614 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_14205 37e9095b37896162a880fc2e2ae442c7 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 8.2E-76 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 C2I25_14205 37e9095b37896162a880fc2e2ae442c7 465 SUPERFAMILY SSF101960 32 462 1.03E-139 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily C2I25_14205 37e9095b37896162a880fc2e2ae442c7 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 1.3E-231 T 14-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 C2I25_11985 4268141fdb36305bc309317d8a3b4d1e 230 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 1 230 35.072 T 14-10-2018 IPR024891 Antiholin-like protein LrgB C2I25_11985 4268141fdb36305bc309317d8a3b4d1e 230 Pfam PF04172 LrgB-like family 14 227 5.1E-69 T 14-10-2018 IPR007300 CidB/LrgB family C2I25_24030 b041b197115885088dc74eaab0e6034d 147 Gene3D G3DSA:1.10.10.10 4 144 1.2E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24030 b041b197115885088dc74eaab0e6034d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 2.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24030 b041b197115885088dc74eaab0e6034d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 2.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24030 b041b197115885088dc74eaab0e6034d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 2.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24030 b041b197115885088dc74eaab0e6034d 147 SMART SM00347 30 130 6.0E-23 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24030 b041b197115885088dc74eaab0e6034d 147 SUPERFAMILY SSF46785 6 141 4.14E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_24030 b041b197115885088dc74eaab0e6034d 147 Pfam PF01047 MarR family 37 94 3.7E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_06815 fac1924b5bcb527e4dd19f7a3ba3ab3f 440 SUPERFAMILY SSF103473 13 420 1.7E-65 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_06815 fac1924b5bcb527e4dd19f7a3ba3ab3f 440 Gene3D G3DSA:1.20.1250.20 13 428 8.2E-70 T 14-10-2018 C2I25_06815 fac1924b5bcb527e4dd19f7a3ba3ab3f 440 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_06815 fac1924b5bcb527e4dd19f7a3ba3ab3f 440 ProSitePatterns PS00216 Sugar transport proteins signature 1. 291 308 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_06815 fac1924b5bcb527e4dd19f7a3ba3ab3f 440 Pfam PF00083 Sugar (and other) transporter 17 235 8.0E-28 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 C2I25_06815 fac1924b5bcb527e4dd19f7a3ba3ab3f 440 Pfam PF07690 Major Facilitator Superfamily 251 426 4.4E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 Pfam PF00226 DnaJ domain 5 66 1.0E-27 T 14-10-2018 IPR001623 DnaJ domain C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 14-10-2018 IPR018253 DnaJ domain, conserved site C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF49493 113 259 2.09E-19 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 SMART SM00271 4 61 2.7E-31 T 14-10-2018 IPR001623 DnaJ domain C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 353 1.0E-142 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 Gene3D G3DSA:2.60.260.20 116 252 7.1E-36 T 14-10-2018 C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 Pfam PF01556 DnaJ C terminal domain 119 336 1.5E-43 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF57938 133 214 1.31E-18 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 Pfam PF00684 DnaJ central domain 146 210 6.1E-14 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 Gene3D G3DSA:2.10.230.10 146 210 7.1E-36 T 14-10-2018 C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 PRINTS PR00625 DnaJ domain signature 41 61 2.8E-31 T 14-10-2018 IPR001623 DnaJ domain C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 PRINTS PR00625 DnaJ domain signature 61 80 2.8E-31 T 14-10-2018 IPR001623 DnaJ domain C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 PRINTS PR00625 DnaJ domain signature 25 40 2.8E-31 T 14-10-2018 IPR001623 DnaJ domain C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 PRINTS PR00625 DnaJ domain signature 7 25 2.8E-31 T 14-10-2018 IPR001623 DnaJ domain C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 Gene3D G3DSA:1.10.287.110 1 110 4.9E-38 T 14-10-2018 IPR036869 Chaperone J-domain superfamily C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 Gene3D G3DSA:2.60.260.20 256 336 3.3E-30 T 14-10-2018 C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF46565 1 104 8.9E-38 T 14-10-2018 IPR036869 Chaperone J-domain superfamily C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF49493 261 347 4.32E-25 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 C2I25_17710 9861a44e442a2309c9b3e8b55a4801ce 371 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 367 41.629 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 C2I25_19040 6477c36cd54d4cfcb2166b08cc43e136 223 Gene3D G3DSA:3.30.110.170 25 220 4.3E-50 T 14-10-2018 C2I25_19040 6477c36cd54d4cfcb2166b08cc43e136 223 Pfam PF04402 Protein of unknown function (DUF541) 23 220 1.2E-38 T 14-10-2018 IPR007497 Protein of unknown function DUF541 C2I25_19040 6477c36cd54d4cfcb2166b08cc43e136 223 Gene3D G3DSA:3.30.70.2970 35 141 4.3E-50 T 14-10-2018 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 548 564 1.9E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 534 548 1.9E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 564 576 1.9E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 PIRSF PIRSF037435 1 595 0.0 T 14-10-2018 IPR017206 Signal transduction histidine kinase, hybrid-type, BC3207, predicted C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 Pfam PF00196 Bacterial regulatory proteins, luxR family 534 588 2.2E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 SUPERFAMILY SSF52172 383 547 1.71E-32 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 SUPERFAMILY SSF46894 527 594 5.78E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 Pfam PF00072 Response regulator receiver domain 386 496 9.5E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 SMART SM00448 383 496 2.1E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 Gene3D G3DSA:3.30.565.10 248 379 1.2E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 Gene3D G3DSA:3.40.50.12740 383 594 1.5E-61 T 14-10-2018 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 SMART SM00421 531 588 4.5E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 Pfam PF07730 Histidine kinase 184 245 7.7E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I25_23675 62ee6ce594e1f442c5a4a2d219c3b0b0 595 SUPERFAMILY SSF55874 252 373 4.19E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_14530 8eb92c709433908e863a905bd0e17bd6 219 Pfam PF06725 3D domain 126 187 6.8E-19 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I25_14530 8eb92c709433908e863a905bd0e17bd6 219 SUPERFAMILY SSF50685 126 168 4.53E-7 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 Gene3D G3DSA:1.10.260.40 3 59 1.5E-23 T 14-10-2018 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 Gene3D G3DSA:3.40.50.2300 156 282 1.9E-81 T 14-10-2018 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 8.7E-21 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 SMART SM00354 1 71 9.9E-36 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 SUPERFAMILY SSF47413 2 59 8.04E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 Pfam PF13377 Periplasmic binding protein-like domain 166 322 2.2E-35 T 14-10-2018 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 14-10-2018 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 Gene3D G3DSA:3.40.50.2300 62 302 1.9E-81 T 14-10-2018 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 SUPERFAMILY SSF53822 60 323 2.9E-81 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.1E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_08180 cc75060497b15a75f6c720e0fe267ac6 323 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.1E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_25825 6f820c5e35b17698a201f21c747934c5 110 Pfam PF13028 Protein of unknown function (DUF3889) 27 106 1.7E-30 T 14-10-2018 IPR024987 Protein of unknown function DUF3889 C2I25_25825 6f820c5e35b17698a201f21c747934c5 110 Gene3D G3DSA:3.10.450.390 24 109 6.8E-31 T 14-10-2018 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 Pfam PF11798 IMS family HHH motif 181 213 1.3E-6 T 14-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 SUPERFAMILY SSF56672 10 249 8.18E-52 T 14-10-2018 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 Gene3D G3DSA:2.30.40.20 29 82 2.7E-47 T 14-10-2018 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 Pfam PF11799 impB/mucB/samB family C-terminal domain 254 364 3.8E-12 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 SUPERFAMILY SSF100879 264 357 1.06E-9 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 Pfam PF00817 impB/mucB/samB family 15 165 1.1E-27 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 Gene3D G3DSA:3.30.70.270 12 246 2.7E-47 T 14-10-2018 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 Gene3D G3DSA:3.30.1490.100 262 366 5.8E-9 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I25_24085 ccd99347f7bd0129afe86b1edfaa3e94 421 Gene3D G3DSA:1.10.150.20 190 243 2.7E-47 T 14-10-2018 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 404 568 9.7E-50 T 14-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 133 7.2E-12 T 14-10-2018 IPR011096 FTP domain C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Pfam PF00746 LPXTG cell wall anchor motif 856 890 2.2E-4 T 14-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 248 401 1.6E-32 T 14-10-2018 IPR013856 Peptidase M4 domain GO:0004222 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Gene3D G3DSA:3.10.450.490 54 144 8.0E-6 T 14-10-2018 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 413 424 2.2E-13 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 392 408 2.2E-13 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 483 499 2.2E-13 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Gene3D G3DSA:2.60.40.10 749 824 5.2E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Gene3D G3DSA:2.60.40.10 666 742 9.1E-33 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Gene3D G3DSA:2.60.40.10 583 658 2.9E-25 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 SUPERFAMILY SSF55486 247 568 1.36E-67 T 14-10-2018 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Pfam PF16403 Domain of unknown function (DUF5011) 591 656 2.6E-14 T 14-10-2018 IPR032179 Domain of unknown function DUF5011 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Pfam PF16403 Domain of unknown function (DUF5011) 756 818 1.2E-13 T 14-10-2018 IPR032179 Domain of unknown function DUF5011 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Pfam PF16403 Domain of unknown function (DUF5011) 676 739 6.2E-16 T 14-10-2018 IPR032179 Domain of unknown function DUF5011 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Gene3D G3DSA:3.10.170.10 247 405 5.9E-37 T 14-10-2018 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 857 890 6.9E-5 T 14-10-2018 C2I25_27015 033d76e2111b2d4572dd9a17dfac56e6 893 Gene3D G3DSA:1.10.390.10 406 568 4.2E-47 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily C2I25_26340 b01ec978c7eabb87cddeacf56a23a607 156 Pfam PF00293 NUDIX domain 25 142 1.0E-20 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_26340 b01ec978c7eabb87cddeacf56a23a607 156 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_26340 b01ec978c7eabb87cddeacf56a23a607 156 PRINTS PR00502 NUDIX hydrolase family signature 61 76 2.6E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_26340 b01ec978c7eabb87cddeacf56a23a607 156 PRINTS PR00502 NUDIX hydrolase family signature 47 61 2.6E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_26340 b01ec978c7eabb87cddeacf56a23a607 156 Gene3D G3DSA:3.90.79.10 3 146 1.7E-39 T 14-10-2018 C2I25_26340 b01ec978c7eabb87cddeacf56a23a607 156 SUPERFAMILY SSF55811 8 151 1.49E-34 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_04360 92ba60d5f25db0aa8fb97e33c035a446 239 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 231 8.8E-87 T 14-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 C2I25_04360 92ba60d5f25db0aa8fb97e33c035a446 239 SUPERFAMILY SSF51366 1 235 3.7E-74 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I25_04360 92ba60d5f25db0aa8fb97e33c035a446 239 Pfam PF00977 Histidine biosynthesis protein 2 227 1.5E-78 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 C2I25_04360 92ba60d5f25db0aa8fb97e33c035a446 239 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 235 36.326 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 C2I25_04360 92ba60d5f25db0aa8fb97e33c035a446 239 Gene3D G3DSA:3.20.20.70 1 238 7.7E-87 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_03850 9ef78c0a5fb71fd4c0c6bf512476a659 90 Gene3D G3DSA:4.10.520.10 1 90 8.2E-42 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I25_03850 9ef78c0a5fb71fd4c0c6bf512476a659 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 C2I25_03850 9ef78c0a5fb71fd4c0c6bf512476a659 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.0E-38 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_03850 9ef78c0a5fb71fd4c0c6bf512476a659 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.7E-22 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_03850 9ef78c0a5fb71fd4c0c6bf512476a659 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.7E-22 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_03850 9ef78c0a5fb71fd4c0c6bf512476a659 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.7E-22 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_03850 9ef78c0a5fb71fd4c0c6bf512476a659 90 SMART SM00411 1 90 8.2E-53 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_03850 9ef78c0a5fb71fd4c0c6bf512476a659 90 SUPERFAMILY SSF47729 1 90 4.27E-36 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I25_04585 52c9e56acfca88f1e0a18b4540400469 306 Pfam PF02016 LD-carboxypeptidase 13 287 2.9E-81 T 14-10-2018 IPR003507 Peptidase family S66 C2I25_04585 52c9e56acfca88f1e0a18b4540400469 306 Gene3D G3DSA:3.40.50.10740 1 152 1.0E-53 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal C2I25_04585 52c9e56acfca88f1e0a18b4540400469 306 PIRSF PIRSF028757 1 299 1.7E-89 T 14-10-2018 IPR003507 Peptidase family S66 C2I25_04585 52c9e56acfca88f1e0a18b4540400469 306 SUPERFAMILY SSF52317 1 157 3.89E-50 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_04585 52c9e56acfca88f1e0a18b4540400469 306 SUPERFAMILY SSF141986 141 293 1.57E-42 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I25_04585 52c9e56acfca88f1e0a18b4540400469 306 Gene3D G3DSA:3.50.30.60 163 295 3.4E-43 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I25_08275 aa67026ec220b0eebd3581641e02eda2 125 Pfam PF02566 OsmC-like protein 22 118 4.8E-21 T 14-10-2018 IPR003718 OsmC/Ohr family C2I25_08275 aa67026ec220b0eebd3581641e02eda2 125 Gene3D G3DSA:3.30.300.20 2 124 1.0E-27 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_08275 aa67026ec220b0eebd3581641e02eda2 125 SUPERFAMILY SSF82784 22 124 3.27E-25 T 14-10-2018 IPR036102 OsmC/Ohr superfamily C2I25_18785 9ee649ee2af43196ea3e5893f1e18833 311 Pfam PF06013 Proteins of 100 residues with WXG 3 88 2.3E-11 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_18785 9ee649ee2af43196ea3e5893f1e18833 311 Pfam PF14410 HNH/ENDO VII superfamily nuclease with conserved GHE residues 237 311 4.0E-24 T 14-10-2018 IPR026835 UPF0720 protein yqcG C2I25_18785 9ee649ee2af43196ea3e5893f1e18833 311 SUPERFAMILY SSF140453 3 93 2.62E-12 T 14-10-2018 IPR036689 ESAT-6-like superfamily C2I25_18785 9ee649ee2af43196ea3e5893f1e18833 311 Gene3D G3DSA:1.10.287.850 1 89 6.1E-27 T 14-10-2018 C2I25_18785 9ee649ee2af43196ea3e5893f1e18833 311 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 90 1.2E-19 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_18785 9ee649ee2af43196ea3e5893f1e18833 311 Pfam PF14449 Pre-toxin TG 114 173 1.2E-15 T 14-10-2018 IPR027797 Pre-toxin TG domain C2I25_28280 65a4e7060a73f5b9fe40c2a0ab6ff390 832 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 636 2.6E-44 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_28280 65a4e7060a73f5b9fe40c2a0ab6ff390 832 Gene3D G3DSA:3.90.1310.20 79 536 5.1E-206 T 14-10-2018 C2I25_28280 65a4e7060a73f5b9fe40c2a0ab6ff390 832 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 94 640 1.8E-177 T 14-10-2018 C2I25_28280 65a4e7060a73f5b9fe40c2a0ab6ff390 832 SUPERFAMILY SSF53955 73 286 6.19E-74 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily C2I25_28280 65a4e7060a73f5b9fe40c2a0ab6ff390 832 Pfam PF00912 Transglycosylase 84 260 1.7E-65 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_28280 65a4e7060a73f5b9fe40c2a0ab6ff390 832 Gene3D G3DSA:1.10.3810.10 94 288 5.1E-206 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_28280 65a4e7060a73f5b9fe40c2a0ab6ff390 832 SUPERFAMILY SSF56601 245 654 2.41E-105 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_28280 65a4e7060a73f5b9fe40c2a0ab6ff390 832 Gene3D G3DSA:3.40.710.10 326 650 5.1E-206 T 14-10-2018 C2I25_15760 0a00dee1c0fa33a7afc15119cee18a40 217 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 27 210 1.0E-62 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 C2I25_15760 0a00dee1c0fa33a7afc15119cee18a40 217 Pfam PF02390 Putative methyltransferase 39 206 2.0E-50 T 14-10-2018 C2I25_15760 0a00dee1c0fa33a7afc15119cee18a40 217 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 30.136 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 C2I25_15760 0a00dee1c0fa33a7afc15119cee18a40 217 Gene3D G3DSA:3.40.50.150 1 213 3.6E-71 T 14-10-2018 C2I25_15760 0a00dee1c0fa33a7afc15119cee18a40 217 SUPERFAMILY SSF53335 25 209 2.67E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_10555 2b7707817f76f859026b1e859f367a23 536 Gene3D G3DSA:3.10.105.10 290 508 6.6E-159 T 14-10-2018 C2I25_10555 2b7707817f76f859026b1e859f367a23 536 SUPERFAMILY SSF53850 32 521 7.74E-131 T 14-10-2018 C2I25_10555 2b7707817f76f859026b1e859f367a23 536 Gene3D G3DSA:3.40.190.10 48 520 6.6E-159 T 14-10-2018 C2I25_10555 2b7707817f76f859026b1e859f367a23 536 PIRSF PIRSF002741 1 528 1.8E-119 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_10555 2b7707817f76f859026b1e859f367a23 536 Gene3D G3DSA:3.90.76.10 68 190 6.6E-159 T 14-10-2018 C2I25_10555 2b7707817f76f859026b1e859f367a23 536 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 84 106 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site C2I25_10555 2b7707817f76f859026b1e859f367a23 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 457 3.8E-86 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_09455 04a753a3350497db7888eab120da6238 554 SUPERFAMILY SSF51011 476 553 1.39E-17 T 14-10-2018 C2I25_09455 04a753a3350497db7888eab120da6238 554 Gene3D G3DSA:2.60.40.1180 477 554 2.1E-21 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_09455 04a753a3350497db7888eab120da6238 554 SMART SM00642 13 415 2.4E-162 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_09455 04a753a3350497db7888eab120da6238 554 Gene3D G3DSA:3.20.20.80 1 109 1.1E-48 T 14-10-2018 C2I25_09455 04a753a3350497db7888eab120da6238 554 Gene3D G3DSA:3.20.20.80 171 476 1.8E-117 T 14-10-2018 C2I25_09455 04a753a3350497db7888eab120da6238 554 Gene3D G3DSA:3.90.400.10 110 170 1.8E-34 T 14-10-2018 C2I25_09455 04a753a3350497db7888eab120da6238 554 Pfam PF00128 Alpha amylase, catalytic domain 28 373 1.8E-116 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_09455 04a753a3350497db7888eab120da6238 554 Pfam PF16657 Maltogenic Amylase, C-terminal domain 476 548 7.4E-9 T 14-10-2018 IPR032091 Maltogenic Amylase, C-terminal C2I25_09455 04a753a3350497db7888eab120da6238 554 SUPERFAMILY SSF51445 4 473 6.58E-155 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_27805 a6d087381c32129ff0bf0901d0859ee4 185 Gene3D G3DSA:1.10.260.40 2 75 2.2E-18 T 14-10-2018 C2I25_27805 a6d087381c32129ff0bf0901d0859ee4 185 SUPERFAMILY SSF47413 3 72 1.74E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_27805 a6d087381c32129ff0bf0901d0859ee4 185 Pfam PF01381 Helix-turn-helix 12 64 1.5E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_27805 a6d087381c32129ff0bf0901d0859ee4 185 Pfam PF07883 Cupin domain 117 176 2.0E-12 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_27805 a6d087381c32129ff0bf0901d0859ee4 185 SMART SM00530 11 66 7.7E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_27805 a6d087381c32129ff0bf0901d0859ee4 185 SUPERFAMILY SSF51182 51 183 1.98E-25 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_27805 a6d087381c32129ff0bf0901d0859ee4 185 Gene3D G3DSA:2.60.120.10 91 184 1.1E-29 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_19495 affe7e6d6d6035ab338e3ee558de9513 217 SUPERFAMILY SSF55073 74 216 1.49E-11 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_19495 affe7e6d6d6035ab338e3ee558de9513 217 Pfam PF00990 Diguanylate cyclase, GGDEF domain 88 216 4.1E-10 T 14-10-2018 IPR000160 GGDEF domain C2I25_19495 affe7e6d6d6035ab338e3ee558de9513 217 Gene3D G3DSA:3.30.70.270 68 213 8.2E-13 T 14-10-2018 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 6.7E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 6.7E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 6.7E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 6.7E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 Gene3D G3DSA:4.10.640.10 2 77 1.0E-31 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 SUPERFAMILY SSF46911 5 75 4.58E-31 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 14-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 7.7E-37 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 Pfam PF01084 Ribosomal protein S18 23 72 1.4E-28 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 77 22.816 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11730 9661c8c3063cfe890c3436e87bdab330 77 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 77 9.0E-24 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 SUPERFAMILY SSF53681 112 265 1.96E-40 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 216 2.1E-43 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 SUPERFAMILY SSF53681 6 108 9.81E-37 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 Gene3D G3DSA:3.40.50.1860 96 208 9.3E-102 T 14-10-2018 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 255 2.1E-89 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 Hamap MF_00258 Glutamate racemase [murI]. 5 257 40.8 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 Gene3D G3DSA:3.40.50.1860 7 256 9.3E-102 T 14-10-2018 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_16850 54411a24e32b747eaf5231484a09c438 269 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 Gene3D G3DSA:2.30.22.10 132 188 2.2E-25 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 SUPERFAMILY SSF58014 38 132 7.32E-26 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 PRINTS PR00773 GrpE protein signature 58 74 1.3E-30 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 PRINTS PR00773 GrpE protein signature 86 101 1.3E-30 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 PRINTS PR00773 GrpE protein signature 140 155 1.3E-30 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 PRINTS PR00773 GrpE protein signature 167 186 1.3E-30 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 Hamap MF_01151 Protein GrpE [grpE]. 2 188 21.368 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 SUPERFAMILY SSF51064 133 188 4.58E-19 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 ProSitePatterns PS01071 grpE protein signature. 143 186 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 Gene3D G3DSA:3.90.20.20 1 131 9.9E-26 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 C2I25_17700 6007ac0640b5e40a826e697faeed7680 188 Pfam PF01025 GrpE 25 188 3.0E-55 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I25_04795 b8afb5aa0dcb62a8ff71292b8bd7b50f 583 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 23 583 9.0E-251 T 14-10-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative C2I25_04795 b8afb5aa0dcb62a8ff71292b8bd7b50f 583 Gene3D G3DSA:1.10.3720.10 311 574 7.4E-33 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_04795 b8afb5aa0dcb62a8ff71292b8bd7b50f 583 Gene3D G3DSA:1.10.3720.10 24 290 8.9E-57 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_04795 b8afb5aa0dcb62a8ff71292b8bd7b50f 583 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 283 2.6E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_04795 b8afb5aa0dcb62a8ff71292b8bd7b50f 583 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 395 572 6.0E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_04795 b8afb5aa0dcb62a8ff71292b8bd7b50f 583 SUPERFAMILY SSF161098 313 568 1.59E-33 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_04795 b8afb5aa0dcb62a8ff71292b8bd7b50f 583 SUPERFAMILY SSF161098 21 287 2.34E-50 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_19910 9adf1d6aac21f7247409c8f6d8a68af2 120 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 38 118 2.8E-24 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 C2I25_19910 9adf1d6aac21f7247409c8f6d8a68af2 120 Pfam PF04977 Septum formation initiator 45 111 7.8E-14 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC C2I25_19910 9adf1d6aac21f7247409c8f6d8a68af2 120 Hamap MF_00910 Cell division protein FtsL [ftsL]. 38 120 13.276 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 C2I25_25520 bd114e2bcda0e07048bf60e561e94faa 247 Gene3D G3DSA:2.20.25.110 142 193 3.3E-20 T 14-10-2018 C2I25_25520 bd114e2bcda0e07048bf60e561e94faa 247 Gene3D G3DSA:3.40.50.150 22 214 3.3E-20 T 14-10-2018 C2I25_25520 bd114e2bcda0e07048bf60e561e94faa 247 SUPERFAMILY SSF53335 7 215 1.89E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_25520 bd114e2bcda0e07048bf60e561e94faa 247 Pfam PF13649 Methyltransferase domain 46 135 1.4E-8 T 14-10-2018 C2I25_17040 973d302fd92bbc925f9f79a9c9ada924 248 Pfam PF01551 Peptidase family M23 148 241 1.7E-21 T 14-10-2018 IPR016047 Peptidase M23 C2I25_17040 973d302fd92bbc925f9f79a9c9ada924 248 SUPERFAMILY SSF51261 92 244 2.3E-20 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_17040 973d302fd92bbc925f9f79a9c9ada924 248 Gene3D G3DSA:2.70.70.10 117 246 4.7E-22 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 Gene3D G3DSA:1.10.1200.10 220 293 4.2E-24 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 SUPERFAMILY SSF47336 219 293 1.44E-11 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 Pfam PF00857 Isochorismatase family 32 203 8.2E-40 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 Gene3D G3DSA:3.40.50.850 1 207 3.7E-76 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 SUPERFAMILY SSF52499 1 217 1.06E-62 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 PIRSF PIRSF001111 1 297 5.2E-135 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 Pfam PF00550 Phosphopantetheine attachment site 224 287 9.6E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 PRINTS PR01398 Isochorismatase signature 112 134 1.3E-45 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 PRINTS PR01398 Isochorismatase signature 63 80 1.3E-45 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 PRINTS PR01398 Isochorismatase signature 186 203 1.3E-45 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 PRINTS PR01398 Isochorismatase signature 80 99 1.3E-45 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 PRINTS PR01398 Isochorismatase signature 168 186 1.3E-45 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 C2I25_28155 f9ea25797c7426cd628bdbd0e8b92ab6 297 PRINTS PR01398 Isochorismatase signature 2 14 1.3E-45 T 14-10-2018 IPR016291 Isochorismatase GO:0008908 C2I25_25455 5ee87998b9fb41ee6837a4e52896e4b7 309 Gene3D G3DSA:3.90.1640.10 1 188 6.7E-83 T 14-10-2018 C2I25_25455 5ee87998b9fb41ee6837a4e52896e4b7 309 Pfam PF02833 DHHA2 domain 183 306 5.8E-22 T 14-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_25455 5ee87998b9fb41ee6837a4e52896e4b7 309 SUPERFAMILY SSF64182 1 307 9.03E-88 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily C2I25_25455 5ee87998b9fb41ee6837a4e52896e4b7 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 46.708 T 14-10-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_25455 5ee87998b9fb41ee6837a4e52896e4b7 309 SMART SM01131 181 307 3.7E-54 T 14-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_25455 5ee87998b9fb41ee6837a4e52896e4b7 309 Gene3D G3DSA:3.10.310.20 190 309 8.2E-38 T 14-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_25455 5ee87998b9fb41ee6837a4e52896e4b7 309 Pfam PF01368 DHH family 3 146 1.1E-31 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_01215 68c26cbcd94bd3a67b653eccb3ae0798 140 Pfam PF00583 Acetyltransferase (GNAT) family 35 129 2.4E-13 T 14-10-2018 IPR000182 GNAT domain C2I25_01215 68c26cbcd94bd3a67b653eccb3ae0798 140 SUPERFAMILY SSF55729 7 134 1.33E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01215 68c26cbcd94bd3a67b653eccb3ae0798 140 Gene3D G3DSA:3.40.630.30 5 140 2.5E-23 T 14-10-2018 C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 SUPERFAMILY SSF63882 7 184 9.81E-50 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 Pfam PF03453 MoeA N-terminal region (domain I and II) 7 175 1.1E-37 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 Pfam PF03454 MoeA C-terminal region (domain IV) 339 410 2.1E-15 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 Pfam PF00994 Probable molybdopterin binding domain 190 325 1.4E-23 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 Gene3D G3DSA:2.40.340.10 337 403 7.0E-115 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 Gene3D G3DSA:3.90.105.10 26 182 7.0E-115 T 14-10-2018 C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 SUPERFAMILY SSF63867 336 412 9.68E-17 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 Gene3D G3DSA:3.40.980.10 183 336 7.0E-115 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 185 322 3.4E-30 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 Gene3D G3DSA:2.170.190.11 49 149 7.0E-115 T 14-10-2018 C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 SMART SM00852 188 326 1.3E-34 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_21750 715c097ef8c9d3e6c5e8d8962f2d3295 435 SUPERFAMILY SSF53218 186 327 1.02E-37 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_04780 f37fbc83eeacd5274dfd85b39bdcd7e4 394 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 125 378 7.9E-19 T 14-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 C2I25_04780 f37fbc83eeacd5274dfd85b39bdcd7e4 394 SUPERFAMILY SSF51735 2 157 1.19E-12 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_04780 f37fbc83eeacd5274dfd85b39bdcd7e4 394 Gene3D G3DSA:3.40.50.720 1 111 1.2E-8 T 14-10-2018 C2I25_04780 f37fbc83eeacd5274dfd85b39bdcd7e4 394 Gene3D G3DSA:3.40.50.720 321 393 7.7E-10 T 14-10-2018 C2I25_04780 f37fbc83eeacd5274dfd85b39bdcd7e4 394 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 101 2.3E-14 T 14-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 C2I25_04780 f37fbc83eeacd5274dfd85b39bdcd7e4 394 Gene3D G3DSA:3.30.360.10 127 317 3.4E-39 T 14-10-2018 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 Gene3D G3DSA:3.30.499.20 3 283 2.0E-97 T 14-10-2018 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 SUPERFAMILY SSF53732 2 454 2.75E-160 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 454 8.6E-214 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 ProSitePatterns PS01244 Aconitase family signature 2. 389 402 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 ProSitePatterns PS00450 Aconitase family signature 1. 329 345 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 118 131 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 132 147 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 333 344 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 107 115 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 208 221 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 389 402 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 81 94 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 283 297 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 PRINTS PR00415 Aconitase family signature 194 207 1.7E-44 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 456 57.029 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 Pfam PF00330 Aconitase family (aconitate hydratase) 7 447 5.4E-152 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_04395 c6d1c6b74d19267ffa4dbd5cec0f8377 464 Gene3D G3DSA:3.30.499.10 317 462 2.6E-50 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 85 93 1.5E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 220 235 1.5E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 61 74 1.5E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 203 215 1.5E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 235 246 1.5E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 Gene3D G3DSA:1.10.10.10 105 160 2.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19095 1df9d779279633f438bfd41efb634b79 252 Gene3D G3DSA:1.20.120.1810 2 104 2.1E-27 T 14-10-2018 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 SUPERFAMILY SSF88946 6 105 7.98E-34 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 Pfam PF04542 Sigma-70 region 2 38 105 4.2E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 Gene3D G3DSA:1.10.10.10 179 252 2.3E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19095 1df9d779279633f438bfd41efb634b79 252 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 249 9.7E-39 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 250 1.5E-88 T 14-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 SUPERFAMILY SSF88659 109 184 5.67E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_19095 1df9d779279633f438bfd41efb634b79 252 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 250 9.2E-118 T 14-10-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 Pfam PF04545 Sigma-70, region 4 199 247 2.3E-15 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 220 246 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 PIRSF PIRSF000770 10 252 3.1E-35 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 Pfam PF04539 Sigma-70 region 3 115 184 1.5E-14 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 C2I25_19095 1df9d779279633f438bfd41efb634b79 252 SUPERFAMILY SSF88659 171 250 3.18E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_27905 452db2692dc270b84346b53da4f7cda0 213 Gene3D G3DSA:3.40.50.300 2 197 1.3E-14 T 14-10-2018 C2I25_27905 452db2692dc270b84346b53da4f7cda0 213 Pfam PF13521 AAA domain 4 157 1.0E-6 T 14-10-2018 IPR038727 NadR/Ttd14, AAA domain C2I25_27905 452db2692dc270b84346b53da4f7cda0 213 SUPERFAMILY SSF52540 3 158 6.28E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 2.6E-68 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 SUPERFAMILY SSF50249 2 137 1.37E-49 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 9.6E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 9.6E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 9.6E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 9.6E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 9.6E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 9.6E-59 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 PIRSF PIRSF002133 1 137 4.4E-49 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.775 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 Pfam PF00164 Ribosomal protein S12/S23 32 136 1.8E-38 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 Gene3D G3DSA:2.40.50.140 1 140 5.8E-63 T 14-10-2018 C2I25_11000 f9858db140009cfbdfdc3d4864a3f9b3 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10460 2a55c05ecaea61cbe4a85192e9d28368 31 Pfam PF13134 Protein of unknown function (DUF3948) 1 26 5.2E-12 T 14-10-2018 IPR025034 Protein of unknown function DUF3948 C2I25_08310 9a24a545d4d884906347e7dba31177f9 323 SUPERFAMILY SSF56112 12 305 2.95E-43 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_08310 9a24a545d4d884906347e7dba31177f9 323 Gene3D G3DSA:3.90.1200.10 125 308 3.1E-19 T 14-10-2018 C2I25_08310 9a24a545d4d884906347e7dba31177f9 323 Pfam PF01636 Phosphotransferase enzyme family 31 253 1.7E-23 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_24275 eb775c50b715cc80cce3db30a68393b0 174 Gene3D G3DSA:3.90.79.10 2 160 4.5E-29 T 14-10-2018 C2I25_24275 eb775c50b715cc80cce3db30a68393b0 174 SUPERFAMILY SSF55811 5 145 2.3E-22 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_24275 eb775c50b715cc80cce3db30a68393b0 174 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_24275 eb775c50b715cc80cce3db30a68393b0 174 Pfam PF00293 NUDIX domain 6 99 5.5E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_06010 8a056f410f3df1cf9d1d8079c7809c0e 637 Pfam PF05569 BlaR1 peptidase M56 17 327 8.2E-61 T 14-10-2018 IPR008756 Peptidase M56 C2I25_06010 8a056f410f3df1cf9d1d8079c7809c0e 637 Gene3D G3DSA:1.10.3950.10 381 531 2.5E-5 T 14-10-2018 IPR038267 Putative ECF-type sigma factor negative effector C2I25_15480 688bdb204eb9921b105487fd70def071 220 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 212 9.2E-39 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_15480 688bdb204eb9921b105487fd70def071 220 Gene3D G3DSA:3.40.50.1860 105 204 8.5E-51 T 14-10-2018 C2I25_15480 688bdb204eb9921b105487fd70def071 220 Gene3D G3DSA:3.40.50.1860 2 210 8.5E-51 T 14-10-2018 C2I25_15480 688bdb204eb9921b105487fd70def071 220 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_15480 688bdb204eb9921b105487fd70def071 220 SUPERFAMILY SSF53681 116 217 2.35E-18 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_15480 688bdb204eb9921b105487fd70def071 220 SUPERFAMILY SSF53681 1 112 8.5E-27 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_15480 688bdb204eb9921b105487fd70def071 220 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 219 5.4E-39 T 14-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 SUPERFAMILY SSF55021 326 400 3.97E-20 T 14-10-2018 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 Pfam PF01842 ACT domain 272 321 9.3E-7 T 14-10-2018 IPR002912 ACT domain C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 SUPERFAMILY SSF55021 250 322 5.19E-13 T 14-10-2018 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 Pfam PF13840 ACT domain 333 396 1.4E-11 T 14-10-2018 IPR027795 CASTOR, ACT domain C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 399 2.2E-118 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 Gene3D G3DSA:3.30.70.260 260 335 1.1E-44 T 14-10-2018 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 Gene3D G3DSA:3.40.1160.10 1 254 1.1E-88 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 Gene3D G3DSA:3.30.70.260 255 398 1.1E-44 T 14-10-2018 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 Pfam PF00696 Amino acid kinase family 3 226 2.4E-52 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 PIRSF PIRSF000726 53 405 3.9E-128 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 PIRSF PIRSF000726 1 61 5.5E-19 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 399 5.2E-143 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_02565 f5dfc036f502e93a682518da6ba2f749 409 SUPERFAMILY SSF53633 3 243 1.96E-72 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_10505 39910123b584443eb890ac454eaac605 268 SUPERFAMILY SSF53850 42 265 1.24E-67 T 14-10-2018 C2I25_10505 39910123b584443eb890ac454eaac605 268 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 48 263 8.0E-70 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 C2I25_10505 39910123b584443eb890ac454eaac605 268 Gene3D G3DSA:3.40.190.10 45 264 1.2E-83 T 14-10-2018 C2I25_10505 39910123b584443eb890ac454eaac605 268 Pfam PF13531 Bacterial extracellular solute-binding protein 43 264 9.0E-49 T 14-10-2018 C2I25_10505 39910123b584443eb890ac454eaac605 268 PIRSF PIRSF004846 1 268 3.3E-90 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 C2I25_10505 39910123b584443eb890ac454eaac605 268 Gene3D G3DSA:3.40.190.10 122 227 1.2E-83 T 14-10-2018 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 4.1E-90 T 14-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 Pfam PF00365 Phosphofructokinase 3 275 2.8E-115 T 14-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 SUPERFAMILY SSF53784 1 316 9.55E-121 T 14-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 2.6E-141 T 14-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 PIRSF PIRSF000532 1 319 1.8E-124 T 14-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 Gene3D G3DSA:3.40.50.460 142 251 4.6E-121 T 14-10-2018 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 Gene3D G3DSA:3.40.50.450 3 278 4.6E-121 T 14-10-2018 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 14-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I25_16300 d6a01d071edc45cc2409cf42b058fda4 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 50.017 T 14-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I25_10930 4d3f43dba4db11a4460bfa8f5c071032 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 14-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10930 4d3f43dba4db11a4460bfa8f5c071032 66 SUPERFAMILY SSF46561 1 64 9.42E-24 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10930 4d3f43dba4db11a4460bfa8f5c071032 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.193 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10930 4d3f43dba4db11a4460bfa8f5c071032 66 Gene3D G3DSA:1.10.287.310 1 66 4.3E-30 T 14-10-2018 C2I25_10930 4d3f43dba4db11a4460bfa8f5c071032 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 1.5E-24 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10930 4d3f43dba4db11a4460bfa8f5c071032 66 Pfam PF00831 Ribosomal L29 protein 4 60 2.6E-26 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_09865 c9354deb3270cd025dc9738f13585945 281 Gene3D G3DSA:3.30.479.30 85 216 3.1E-10 T 14-10-2018 C2I25_09865 c9354deb3270cd025dc9738f13585945 281 SMART SM00244 49 214 3.1E-11 T 14-10-2018 IPR001107 Band 7 domain C2I25_09865 c9354deb3270cd025dc9738f13585945 281 Pfam PF01145 SPFH domain / Band 7 family 53 228 1.3E-22 T 14-10-2018 IPR001107 Band 7 domain C2I25_09865 c9354deb3270cd025dc9738f13585945 281 SUPERFAMILY SSF117892 87 217 1.96E-12 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily C2I25_20410 b9ad7804f33b0ff327e4a5fa0250fe6d 420 Pfam PF02163 Peptidase family M50 8 406 6.6E-82 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 C2I25_20410 b9ad7804f33b0ff327e4a5fa0250fe6d 420 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 419 4.1E-113 T 14-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 C2I25_20410 b9ad7804f33b0ff327e4a5fa0250fe6d 420 Gene3D G3DSA:2.30.42.10 201 289 1.7E-23 T 14-10-2018 C2I25_20410 b9ad7804f33b0ff327e4a5fa0250fe6d 420 Pfam PF13180 PDZ domain 203 267 1.2E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_20410 b9ad7804f33b0ff327e4a5fa0250fe6d 420 SUPERFAMILY SSF50156 174 268 3.42E-20 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I25_20410 b9ad7804f33b0ff327e4a5fa0250fe6d 420 SMART SM00228 185 259 1.1E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_03940 e02200de2a1f658b2bdf34ff4bbd3194 78 Pfam PF13106 Domain of unknown function (DUF3961) 35 73 7.4E-31 T 14-10-2018 IPR025081 Domain of unknown function DUF3961 C2I25_12390 5e8832075e51333ab3577f4bce999bb8 300 Pfam PF00005 ABC transporter 20 156 3.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_12390 5e8832075e51333ab3577f4bce999bb8 300 SUPERFAMILY SSF52540 3 220 1.38E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12390 5e8832075e51333ab3577f4bce999bb8 300 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_12390 5e8832075e51333ab3577f4bce999bb8 300 Gene3D G3DSA:3.40.50.300 1 231 8.0E-67 T 14-10-2018 C2I25_12390 5e8832075e51333ab3577f4bce999bb8 300 SMART SM00382 29 205 2.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26785 8b0a7161610815f7c547b849242af709 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 9.5E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26785 8b0a7161610815f7c547b849242af709 482 Gene3D G3DSA:1.10.10.10 6 87 7.3E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_26785 8b0a7161610815f7c547b849242af709 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26785 8b0a7161610815f7c547b849242af709 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26785 8b0a7161610815f7c547b849242af709 482 Gene3D G3DSA:3.40.640.10 153 372 9.8E-98 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_26785 8b0a7161610815f7c547b849242af709 482 Pfam PF00155 Aminotransferase class I and II 146 469 1.7E-27 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_26785 8b0a7161610815f7c547b849242af709 482 SUPERFAMILY SSF53383 109 478 1.79E-85 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_26785 8b0a7161610815f7c547b849242af709 482 SMART SM00345 17 76 3.6E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26785 8b0a7161610815f7c547b849242af709 482 SUPERFAMILY SSF46785 7 84 8.44E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_26785 8b0a7161610815f7c547b849242af709 482 Gene3D G3DSA:3.90.1150.10 115 473 9.8E-98 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_14910 8336376d2b786b67f4f1a8f159afa2b8 482 SUPERFAMILY SSF56801 4 481 1.44E-138 T 14-10-2018 C2I25_14910 8336376d2b786b67f4f1a8f159afa2b8 482 Pfam PF00501 AMP-binding enzyme 14 387 8.4E-89 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_14910 8336376d2b786b67f4f1a8f159afa2b8 482 Pfam PF13193 AMP-binding enzyme C-terminal domain 397 469 3.9E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_14910 8336376d2b786b67f4f1a8f159afa2b8 482 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_14910 8336376d2b786b67f4f1a8f159afa2b8 482 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 30 475 2.2E-144 T 14-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 C2I25_14910 8336376d2b786b67f4f1a8f159afa2b8 482 Gene3D G3DSA:3.30.300.310 385 482 6.3E-36 T 14-10-2018 C2I25_14910 8336376d2b786b67f4f1a8f159afa2b8 482 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 5 478 48.996 T 14-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 C2I25_14910 8336376d2b786b67f4f1a8f159afa2b8 482 Gene3D G3DSA:3.40.50.12780 1 384 4.1E-121 T 14-10-2018 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 SUPERFAMILY SSF81338 2 234 1.83E-73 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 Pfam PF00230 Major intrinsic protein 3 230 2.1E-47 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 230 1.7E-63 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 2 21 6.1E-53 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 81 100 6.1E-53 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 44 68 6.1E-53 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 136 154 6.1E-53 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 213 233 6.1E-53 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 166 188 6.1E-53 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 ProSitePatterns PS00221 MIP family signature. 62 70 - T 14-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 C2I25_06275 7ede0d2ea4b9bd77c23fdec3a9e90145 273 Gene3D G3DSA:1.20.1080.10 1 242 1.2E-75 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 119 138 8.8E-5 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 8.8E-5 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 216 234 8.8E-5 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 SUPERFAMILY SSF101801 259 325 2.35E-8 T 14-10-2018 IPR036429 SpoA-like superfamily C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 258 325 4.6E-13 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 PIRSF PIRSF002888 2 328 8.8E-58 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 Pfam PF02154 Flagellar motor switch protein FliM 40 234 1.9E-23 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 Gene3D G3DSA:3.40.1550.10 46 236 8.5E-36 T 14-10-2018 IPR028976 CheC-like superfamily C2I25_03045 ef638c35bdf8e19ee9b01cd8174b895f 328 SUPERFAMILY SSF103039 47 234 2.17E-5 T 14-10-2018 IPR028976 CheC-like superfamily C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 SMART SM00448 3 116 1.1E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.2E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.2E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.2E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 Pfam PF00072 Response regulator receiver domain 6 116 1.2E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 SUPERFAMILY SSF46894 138 209 2.75E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 2.1E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 SUPERFAMILY SSF52172 2 132 1.57E-35 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 SMART SM00421 148 205 1.9E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_00145 2a561df9f40ee40aa1d3a5701f36b633 213 Gene3D G3DSA:3.40.50.12740 3 210 3.4E-74 T 14-10-2018 C2I25_02020 e89034e9c11a97a1ebba097d80923550 216 SUPERFAMILY SSF52833 1 200 3.8E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_02020 e89034e9c11a97a1ebba097d80923550 216 Pfam PF01323 DSBA-like thioredoxin domain 6 193 4.1E-30 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 C2I25_02020 e89034e9c11a97a1ebba097d80923550 216 Gene3D G3DSA:3.40.30.10 1 196 3.0E-39 T 14-10-2018 C2I25_02020 e89034e9c11a97a1ebba097d80923550 216 ProSitePatterns PS00195 Glutaredoxin active site. 7 23 - T 14-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 C2I25_22715 0ad4640b5f12e3c3b581315d5469c3b9 390 SUPERFAMILY SSF53335 4 330 1.0E-79 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_22715 0ad4640b5f12e3c3b581315d5469c3b9 390 Pfam PF02353 Mycolic acid cyclopropane synthetase 104 371 2.6E-103 T 14-10-2018 C2I25_22715 0ad4640b5f12e3c3b581315d5469c3b9 390 PIRSF PIRSF003085 6 389 3.1E-130 T 14-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 C2I25_22715 0ad4640b5f12e3c3b581315d5469c3b9 390 Gene3D G3DSA:3.40.50.150 112 379 5.6E-99 T 14-10-2018 C2I25_11740 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Gene3D G3DSA:3.90.1640.10 317 532 1.8E-50 T 14-10-2018 C2I25_11740 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 SUPERFAMILY SSF64182 339 641 8.24E-70 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily C2I25_11740 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Pfam PF02272 DHHA1 domain 518 644 2.1E-11 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I25_11740 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 PIRSF PIRSF026583 1 657 1.6E-277 T 14-10-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA C2I25_11740 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Gene3D G3DSA:3.10.310.30 533 652 4.5E-7 T 14-10-2018 C2I25_11740 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 SMART SM00267 132 299 3.4E-5 T 14-10-2018 IPR000160 GGDEF domain C2I25_11740 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Pfam PF01368 DHH family 339 496 1.9E-22 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_11740 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Gene3D G3DSA:3.30.450.20 53 161 7.9E-32 T 14-10-2018 C2I25_13805 9beb976163161a77b5e4612bf83859af 192 Gene3D G3DSA:3.40.50.450 1 191 1.2E-77 T 14-10-2018 C2I25_13805 9beb976163161a77b5e4612bf83859af 192 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 179 1.2E-62 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG C2I25_13805 9beb976163161a77b5e4612bf83859af 192 Pfam PF03641 Possible lysine decarboxylase 46 175 5.0E-41 T 14-10-2018 IPR031100 LOG family C2I25_13805 9beb976163161a77b5e4612bf83859af 192 SUPERFAMILY SSF102405 1 179 1.24E-58 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.10 3633 4001 7.4E-124 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF13193 AMP-binding enzyme C-terminal domain 869 942 9.4E-6 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF13193 AMP-binding enzyme C-terminal domain 3446 3519 9.5E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 192 454 3.89E-37 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.300.30 2382 2488 8.2E-27 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.300.30 3433 3533 4.7E-29 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00550 Phosphopantetheine attachment site 968 1033 7.3E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00550 Phosphopantetheine attachment site 2499 2560 3.3E-12 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00550 Phosphopantetheine attachment site 3548 3611 2.0E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.40.50.12780 461 853 8.7E-120 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.40.50.12780 1972 2380 1.6E-125 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF47336 959 1034 5.76E-17 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 1055 1224 1.19E-34 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.10 2587 2945 2.5E-133 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 2588 2751 1.41E-38 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.30 193 443 7.9E-109 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF56801 2995 3559 3.01E-134 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 ProSitePatterns PS00455 Putative AMP-binding domain signature. 613 624 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.30 1697 1955 5.3E-115 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 15 191 9.78E-39 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF56801 1945 2510 2.22E-135 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.30 1215 1486 8.2E-54 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:1.10.1200.10 3534 3619 7.2E-22 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:1.10.1200.10 957 1039 1.8E-21 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:1.10.1200.10 2489 2570 4.6E-20 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 3817 4055 5.0E-44 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 2764 3002 6.23E-53 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.40.50.12780 3021 3432 2.2E-111 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 1696 1943 1.02E-41 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00501 AMP-binding enzyme 3035 3438 4.0E-89 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00501 AMP-binding enzyme 1980 2388 3.4E-84 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00501 AMP-binding enzyme 468 861 4.3E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.300.30 856 956 1.4E-26 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.30 3811 4056 7.4E-124 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3174 3185 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2122 2133 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.30 2755 3000 2.5E-133 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF47336 3539 3611 1.44E-16 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 3633 3807 4.52E-38 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 1230 1484 2.89E-27 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3056 3462 6.1E-113 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 489 885 5.4E-118 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2001 2412 1.4E-119 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1352 1505 4.5E-42 T 14-10-2018 IPR010060 Non-ribosomal peptide synthase C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF56801 426 980 4.45E-145 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.10 1040 1214 4.5E-43 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF52777 1518 1695 2.22E-43 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SUPERFAMILY SSF47336 2491 2563 1.7E-15 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SMART SM01294 968 1033 0.0016 T 14-10-2018 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.10 1518 1891 5.3E-115 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SMART SM00823 Phosphopantetheine attachment site 3546 3615 0.79 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SMART SM00823 Phosphopantetheine attachment site 2498 2567 0.0047 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 SMART SM00823 Phosphopantetheine attachment site 967 1037 4.8E-6 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 ProSitePatterns PS00012 Phosphopantetheine attachment site. 993 1008 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00668 Condensation domain 10 448 6.3E-95 T 14-10-2018 IPR001242 Condensation domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00668 Condensation domain 3630 4061 1.6E-103 T 14-10-2018 IPR001242 Condensation domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00668 Condensation domain 1051 1492 3.4E-73 T 14-10-2018 IPR001242 Condensation domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00668 Condensation domain 1513 1957 8.3E-82 T 14-10-2018 IPR001242 Condensation domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Pfam PF00668 Condensation domain 2582 3015 4.6E-118 T 14-10-2018 IPR001242 Condensation domain C2I25_02050 4a3825e9ed7a1ec87c5c2335a5abb19b 4079 Gene3D G3DSA:3.30.559.10 15 379 7.9E-109 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 4.4E-85 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 Gene3D G3DSA:3.90.230.10 1 248 5.8E-96 T 14-10-2018 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 36.696 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 Pfam PF00557 Metallopeptidase family M24 12 239 6.4E-49 T 14-10-2018 IPR000994 Peptidase M24 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 2.3E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 2.3E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 2.3E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 2.3E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_03560 dd3adfdee50ee0027e10c55fc72b727f 248 SUPERFAMILY SSF55920 1 247 2.62E-78 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I25_01620 1342fbcfccc56a785aed37425c06c834 95 SMART SM00966 8 51 4.8E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_01620 1342fbcfccc56a785aed37425c06c834 95 SUPERFAMILY SSF89447 1 51 1.23E-15 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I25_01620 1342fbcfccc56a785aed37425c06c834 95 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 49 2.6E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_01620 1342fbcfccc56a785aed37425c06c834 95 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 7 48 1.3E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_01620 1342fbcfccc56a785aed37425c06c834 95 Gene3D G3DSA:2.10.260.10 1 54 4.2E-24 T 14-10-2018 C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 SMART SM01134 73 231 1.1E-61 T 14-10-2018 C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 Pfam PF00455 DeoR C terminal sensor domain 75 228 1.7E-46 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.9E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.9E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 5.4E-17 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 SUPERFAMILY SSF46785 5 78 4.42E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 Gene3D G3DSA:1.10.10.10 8 66 4.7E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 SMART SM00420 6 58 3.6E-18 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 SUPERFAMILY SSF100950 74 231 6.91E-36 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_20935 b2a8bb7e551ac2ed20a30bcbb8ca4e6b 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.0E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.0E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.0E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 8.0E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 8.0E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 8.0E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 Pfam PF00106 short chain dehydrogenase 8 193 1.3E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.7E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 SUPERFAMILY SSF51735 6 259 6.53E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22880 d8576857ca4ffccfa3f37db00b75e808 264 Gene3D G3DSA:3.40.50.720 1 264 1.1E-80 T 14-10-2018 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 Gene3D G3DSA:3.90.840.10 51 386 9.8E-140 T 14-10-2018 IPR036363 Thiol-activated cytolysin, alpha-beta domain superfamily GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 SUPERFAMILY SSF56978 44 511 9.29E-205 T 14-10-2018 IPR036359 Thiol-activated cytolysin superfamily GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 Pfam PF17440 Thiol-activated cytolysin beta sandwich domain 406 506 1.1E-40 T 14-10-2018 IPR035390 Thiol-activated cytolysin C-terminal C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 116 132 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 190 205 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 271 294 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 324 341 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 486 506 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 372 399 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 428 444 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 411 428 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 132 150 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 58 75 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 88 110 9.6E-104 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 Gene3D G3DSA:3.40.30.40 192 362 9.8E-140 T 14-10-2018 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 Pfam PF01289 Thiol-activated cytolysin 51 402 1.4E-145 T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 ProSitePatterns PS00481 Thiol-activated cytolysins signature. 470 481 - T 14-10-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 Gene3D G3DSA:2.60.40.1430 404 512 5.1E-48 T 14-10-2018 IPR038700 Thiol-activated cytolysin, C-terminal domain superfamily C2I25_13635 cff2232d1e1feec08ba30394f14d33d0 512 Gene3D G3DSA:3.30.1040.20 67 398 9.8E-140 T 14-10-2018 C2I25_21550 8e32ffa432677e0a3fa358af40e97e31 225 Gene3D G3DSA:3.40.50.2300 1 121 4.0E-39 T 14-10-2018 C2I25_21550 8e32ffa432677e0a3fa358af40e97e31 225 SMART SM00862 150 223 3.0E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_21550 8e32ffa432677e0a3fa358af40e97e31 225 Gene3D G3DSA:1.10.10.10 122 225 2.0E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_21550 8e32ffa432677e0a3fa358af40e97e31 225 Pfam PF00072 Response regulator receiver domain 5 113 2.3E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_21550 8e32ffa432677e0a3fa358af40e97e31 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 4.2E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_21550 8e32ffa432677e0a3fa358af40e97e31 225 SUPERFAMILY SSF52172 3 182 8.64E-42 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_21550 8e32ffa432677e0a3fa358af40e97e31 225 SMART SM00448 3 113 2.2E-45 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 SUPERFAMILY SSF88659 80 157 2.62E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 SUPERFAMILY SSF54427 169 285 6.19E-9 T 14-10-2018 IPR032710 NTF2-like domain superfamily C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 Pfam PF04542 Sigma-70 region 2 6 71 8.3E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 6 285 1.8E-122 T 14-10-2018 IPR014303 RNA polymerase sigma-70, ECF type C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 SUPERFAMILY SSF88946 4 91 4.87E-19 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 Pfam PF08281 Sigma-70, region 4 106 157 3.2E-11 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 159 3.5E-22 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 Gene3D G3DSA:1.10.1740.10 1 74 1.4E-12 T 14-10-2018 C2I25_27765 049089e3cdb86c825f2b87bc2839d88d 289 Gene3D G3DSA:1.10.10.10 109 161 1.1E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_12110 267b460e4417b156458e5a24e72f599b 523 SMART SM00065 197 326 0.0031 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_12110 267b460e4417b156458e5a24e72f599b 523 SMART SM00065 25 176 9.9E-4 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_12110 267b460e4417b156458e5a24e72f599b 523 SUPERFAMILY SSF55874 403 522 9.45E-12 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_12110 267b460e4417b156458e5a24e72f599b 523 SUPERFAMILY SSF55781 28 179 3.27E-19 T 14-10-2018 C2I25_12110 267b460e4417b156458e5a24e72f599b 523 Gene3D G3DSA:3.30.565.10 404 522 1.7E-23 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_12110 267b460e4417b156458e5a24e72f599b 523 Pfam PF07730 Histidine kinase 333 400 7.7E-21 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I25_12110 267b460e4417b156458e5a24e72f599b 523 SUPERFAMILY SSF55781 185 344 3.71E-13 T 14-10-2018 C2I25_12110 267b460e4417b156458e5a24e72f599b 523 Pfam PF13492 GAF domain 203 318 1.9E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_12110 267b460e4417b156458e5a24e72f599b 523 Pfam PF13185 GAF domain 29 166 6.6E-13 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_12110 267b460e4417b156458e5a24e72f599b 523 Gene3D G3DSA:3.30.450.40 7 178 2.9E-22 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_12110 267b460e4417b156458e5a24e72f599b 523 Gene3D G3DSA:3.30.450.40 200 333 1.8E-13 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_03655 09d8ac516af54123974008fd69b968bd 215 SUPERFAMILY SSF48150 1 210 1.73E-74 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 Gene3D G3DSA:1.10.1670.10 16 205 3.6E-80 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 SMART SM00478 39 187 6.5E-68 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 Gene3D G3DSA:1.10.340.30 22 133 3.6E-80 T 14-10-2018 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 170 6.1E-25 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.462 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 TIGRFAM TIGR01083 nth: endonuclease III 6 196 1.8E-86 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 Pfam PF00633 Helix-hairpin-helix motif 101 128 2.3E-9 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 PIRSF PIRSF001435 1 213 2.5E-59 T 14-10-2018 C2I25_03655 09d8ac516af54123974008fd69b968bd 215 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 C2I25_19205 2c4363d057c9302ff77c906081410954 243 SMART SM00866 95 234 9.8E-51 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_19205 2c4363d057c9302ff77c906081410954 243 SUPERFAMILY SSF46785 4 78 2.73E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19205 2c4363d057c9302ff77c906081410954 243 Gene3D G3DSA:3.40.1410.10 75 243 8.5E-59 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_19205 2c4363d057c9302ff77c906081410954 243 Gene3D G3DSA:1.10.10.10 8 74 3.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19205 2c4363d057c9302ff77c906081410954 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.1E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_19205 2c4363d057c9302ff77c906081410954 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.0E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_19205 2c4363d057c9302ff77c906081410954 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.0E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_19205 2c4363d057c9302ff77c906081410954 243 SUPERFAMILY SSF64288 62 241 3.61E-58 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_19205 2c4363d057c9302ff77c906081410954 243 SMART SM00345 15 74 7.6E-24 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_19205 2c4363d057c9302ff77c906081410954 243 Pfam PF07702 UTRA domain 95 234 3.4E-47 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_04760 837e9cdbb1b23dcef5b3325b158132de 209 SUPERFAMILY SSF53639 7 204 3.14E-28 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I25_04760 837e9cdbb1b23dcef5b3325b158132de 209 Gene3D G3DSA:3.40.225.10 6 207 3.7E-22 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I25_04760 837e9cdbb1b23dcef5b3325b158132de 209 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 193 1.6E-20 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I25_04760 837e9cdbb1b23dcef5b3325b158132de 209 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 204 70.525 T 14-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 C2I25_04760 837e9cdbb1b23dcef5b3325b158132de 209 SMART SM01007 9 196 2.7E-16 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 SUPERFAMILY SSF46906 67 140 3.79E-27 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 2.5E-31 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 Gene3D G3DSA:1.10.10.250 72 140 2.9E-29 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 SUPERFAMILY SSF54747 3 72 1.83E-30 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.8E-65 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.9E-25 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 SMART SM00649 9 140 2.3E-87 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 Gene3D G3DSA:3.30.1550.10 2 71 3.3E-34 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-16 T 14-10-2018 C2I25_11040 3c6bbedfc44a957c95a670e0f61b8a91 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.612 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 C2I25_00730 e6ce7ec2fe2ca787538330f8eedadb7c 400 Pfam PF14550 Putative phage serine protease XkdF 44 158 9.0E-42 T 14-10-2018 IPR027924 Phage-like element PBSX protein, XkdF C2I25_17535 233e2bb18eaeeeb454fc1c229df50e41 294 Gene3D G3DSA:3.40.50.1820 26 287 1.5E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_17535 233e2bb18eaeeeb454fc1c229df50e41 294 Pfam PF00561 alpha/beta hydrolase fold 190 273 2.5E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_17535 233e2bb18eaeeeb454fc1c229df50e41 294 Pfam PF00561 alpha/beta hydrolase fold 65 164 1.5E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_17535 233e2bb18eaeeeb454fc1c229df50e41 294 SUPERFAMILY SSF53474 43 287 2.5E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_17535 233e2bb18eaeeeb454fc1c229df50e41 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 105 2.6E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_17535 233e2bb18eaeeeb454fc1c229df50e41 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 2.6E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_17535 233e2bb18eaeeeb454fc1c229df50e41 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 162 2.6E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 126 1.1E-25 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 248 4.6E-32 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 SMART SM00480 17 371 3.0E-107 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 374 4.9E-24 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 PIRSF PIRSF000804 1 376 7.5E-94 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 SUPERFAMILY SSF55979 251 374 1.0E-22 T 14-10-2018 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 1.3E-91 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 SUPERFAMILY SSF55979 132 248 4.56E-27 T 14-10-2018 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 SUPERFAMILY SSF55979 1 127 1.4E-22 T 14-10-2018 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 Gene3D G3DSA:3.10.150.10 1 247 8.5E-108 T 14-10-2018 C2I25_26140 67c00617d71ff79b29a6690e093d9716 376 Gene3D G3DSA:3.70.10.10 144 373 8.5E-108 T 14-10-2018 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SMART SM00487 620 810 3.7E-36 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SUPERFAMILY SSF143517 1015 1168 1.23E-34 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Gene3D G3DSA:3.90.1150.50 1020 1175 1.1E-39 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Gene3D G3DSA:2.30.30.840 503 561 8.9E-247 T 14-10-2018 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SUPERFAMILY SSF52540 802 1008 4.44E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Pfam PF00270 DEAD/DEAH box helicase 625 784 2.1E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Pfam PF03461 TRCF domain 1025 1117 5.0E-26 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Pfam PF00271 Helicase conserved C-terminal domain 828 929 2.0E-17 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Gene3D G3DSA:3.40.50.11180 36 326 5.0E-63 T 14-10-2018 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 27 1118 28.895 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SMART SM00982 1024 1124 3.4E-38 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Gene3D G3DSA:3.40.50.300 562 801 8.9E-247 T 14-10-2018 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SUPERFAMILY SSF52540 377 490 2.6E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SUPERFAMILY SSF141259 490 568 1.7E-26 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SUPERFAMILY SSF52540 543 803 1.46E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Pfam PF02559 CarD-like/TRCF domain 500 595 7.0E-32 T 14-10-2018 IPR003711 CarD-like/TRCF domain C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SMART SM00490 846 930 2.7E-19 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SUPERFAMILY SSF52540 13 366 9.93E-90 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 SMART SM01058 499 596 5.8E-50 T 14-10-2018 IPR003711 CarD-like/TRCF domain C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Gene3D G3DSA:3.30.2060.10 140 225 5.0E-63 T 14-10-2018 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 Gene3D G3DSA:3.40.50.300 498 1008 8.9E-247 T 14-10-2018 C2I25_11345 5cbf1066ce269b75cf0af6694e3c14f2 1176 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1098 0.0 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 SUPERFAMILY SSF81338 2 219 3.27E-57 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 Gene3D G3DSA:1.20.1080.10 1 219 8.9E-64 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 PRINTS PR00783 Major intrinsic protein family signature 3 22 8.9E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 PRINTS PR00783 Major intrinsic protein family signature 78 97 8.9E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 PRINTS PR00783 Major intrinsic protein family signature 41 65 8.9E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 PRINTS PR00783 Major intrinsic protein family signature 196 216 8.9E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 PRINTS PR00783 Major intrinsic protein family signature 127 145 8.9E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 PRINTS PR00783 Major intrinsic protein family signature 157 179 8.9E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 Pfam PF00230 Major intrinsic protein 2 212 1.4E-46 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I25_16795 16649cfb27a9dc7b50e66663a05cc56e 221 ProSitePatterns PS00221 MIP family signature. 59 67 - T 14-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 TIGRFAM TIGR00235 udk: uridine kinase 2 207 9.7E-91 T 14-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 8 193 2.3E-40 T 14-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 Hamap MF_00551 Uridine kinase [udk]. 3 207 40.893 T 14-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 SUPERFAMILY SSF52540 4 198 3.93E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 36 47 1.4E-36 T 14-10-2018 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 173 186 1.4E-36 T 14-10-2018 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 6 23 1.4E-36 T 14-10-2018 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 137 147 1.4E-36 T 14-10-2018 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 81 96 1.4E-36 T 14-10-2018 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 151 162 1.4E-36 T 14-10-2018 C2I25_17375 bca9c1ccea591a946729d86e30851eff 212 Gene3D G3DSA:3.40.50.300 2 211 1.1E-65 T 14-10-2018 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 1.8E-18 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.8E-18 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 PRINTS PR00139 Asparaginase/glutaminase family signature 80 98 1.8E-18 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 PIRSF PIRSF001220 1 324 1.1E-97 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 SMART SM00870 3 318 2.0E-144 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 81 91 - T 14-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 PIRSF PIRSF500176 1 324 1.9E-93 T 14-10-2018 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 SUPERFAMILY SSF53774 2 322 2.62E-103 T 14-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 14-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 Gene3D G3DSA:3.40.50.40 208 322 3.5E-31 T 14-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 Gene3D G3DSA:3.40.50.1170 1 207 5.5E-67 T 14-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 C2I25_03925 247d219c850ce85025bdeb0cc5946843 324 Pfam PF00710 Asparaginase, N-terminal 3 191 1.7E-60 T 14-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 C2I25_18995 f629674358ce6e10eea253c289d46ae6 151 SUPERFAMILY SSF46785 6 142 5.14E-38 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_18995 f629674358ce6e10eea253c289d46ae6 151 Pfam PF01475 Ferric uptake regulator family 16 136 1.2E-38 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 C2I25_18995 f629674358ce6e10eea253c289d46ae6 151 Gene3D G3DSA:1.10.10.10 1 88 5.8E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_18995 f629674358ce6e10eea253c289d46ae6 151 Gene3D G3DSA:3.30.1490.190 93 150 1.8E-18 T 14-10-2018 C2I25_22725 fda1f43d9067f6a617d8d995a2ce8ffb 245 SMART SM00345 13 72 8.8E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_22725 fda1f43d9067f6a617d8d995a2ce8ffb 245 SMART SM00866 93 232 7.1E-27 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_22725 fda1f43d9067f6a617d8d995a2ce8ffb 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.2E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_22725 fda1f43d9067f6a617d8d995a2ce8ffb 245 SUPERFAMILY SSF46785 7 76 2.73E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22725 fda1f43d9067f6a617d8d995a2ce8ffb 245 SUPERFAMILY SSF64288 60 237 3.0E-40 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_22725 fda1f43d9067f6a617d8d995a2ce8ffb 245 Pfam PF07702 UTRA domain 95 231 1.2E-27 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_22725 fda1f43d9067f6a617d8d995a2ce8ffb 245 Gene3D G3DSA:1.10.10.10 9 75 5.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22725 fda1f43d9067f6a617d8d995a2ce8ffb 245 Gene3D G3DSA:3.40.1410.10 90 232 1.8E-32 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_03670 aac7f1fe30bf49f625cdea83be1c47ca 167 SUPERFAMILY SSF54403 94 164 4.76E-17 T 14-10-2018 C2I25_03670 aac7f1fe30bf49f625cdea83be1c47ca 167 Pfam PF03413 Peptidase propeptide and YPEB domain 95 162 1.7E-5 T 14-10-2018 IPR025711 PepSY domain C2I25_03670 aac7f1fe30bf49f625cdea83be1c47ca 167 Gene3D G3DSA:3.10.450.40 23 93 8.9E-21 T 14-10-2018 C2I25_03670 aac7f1fe30bf49f625cdea83be1c47ca 167 SUPERFAMILY SSF54403 33 94 1.53E-17 T 14-10-2018 C2I25_03670 aac7f1fe30bf49f625cdea83be1c47ca 167 Gene3D G3DSA:3.10.450.40 94 164 4.7E-23 T 14-10-2018 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 2.8E-52 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 SUPERFAMILY SSF47928 3 105 1.15E-27 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 4.1E-53 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 21.658 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 Gene3D G3DSA:1.10.520.20 3 106 2.1E-16 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 74 85 2.7E-28 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 151 169 2.7E-28 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 136 151 2.7E-28 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 85 99 2.7E-28 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 6 25 2.7E-28 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12640 72a52279f24ffd1d302ac09dff7a5914 180 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 14-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_15190 1c741981ec596b8b341c10d88c987c5f 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 19 221 1.1E-48 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_15190 1c741981ec596b8b341c10d88c987c5f 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 227 281 2.2E-19 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_15190 1c741981ec596b8b341c10d88c987c5f 290 PIRSF PIRSF006483 1 289 9.8E-76 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_15190 1c741981ec596b8b341c10d88c987c5f 290 Gene3D G3DSA:3.30.70.120 199 273 2.8E-15 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 39.116 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 Gene3D G3DSA:3.40.50.10990 204 374 3.6E-78 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 208 395 8.8E-81 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 42.045 T 14-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 55.766 T 14-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 2.5E-86 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 SUPERFAMILY SSF55821 2 201 8.47E-87 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 SUPERFAMILY SSF142695 203 373 6.02E-74 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 PIRSF PIRSF001259 1 397 1.9E-190 T 14-10-2018 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 1.9E-82 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 Pfam PF00925 GTP cyclohydrolase II 206 370 8.8E-77 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I25_18890 6eaa4a11b9365f2298961a7c5e6400b1 397 Gene3D G3DSA:3.90.870.10 1 203 1.4E-91 T 14-10-2018 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Gene3D G3DSA:1.10.3060.10 570 775 0.0 T 14-10-2018 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 SUPERFAMILY SSF52540 397 568 3.6E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Pfam PF01043 SecA preprotein cross-linking domain 230 338 3.9E-41 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 SUPERFAMILY SSF52540 5 395 2.73E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Pfam PF07517 SecA DEAD-like domain 6 382 8.7E-131 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Gene3D G3DSA:3.40.50.300 397 569 0.0 T 14-10-2018 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 779 19.741 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 SUPERFAMILY SSF81767 225 348 1.31E-47 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 14-10-2018 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 SMART SM00957 5 382 8.4E-288 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 SUPERFAMILY SSF81886 570 823 4.71E-80 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Gene3D G3DSA:3.40.50.300 14 396 0.0 T 14-10-2018 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Pfam PF02810 SEC-C motif 815 832 4.6E-8 T 14-10-2018 IPR004027 SEC-C motif C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Pfam PF00271 Helicase conserved C-terminal domain 419 529 8.0E-6 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 SMART SM00958 226 338 6.1E-65 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 PRINTS PR00906 SecA protein signature 99 113 2.2E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 PRINTS PR00906 SecA protein signature 115 125 2.2E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 PRINTS PR00906 SecA protein signature 168 188 2.2E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 PRINTS PR00906 SecA protein signature 393 406 2.2E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 PRINTS PR00906 SecA protein signature 61 85 2.2E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 PRINTS PR00906 SecA protein signature 319 341 2.2E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 PRINTS PR00906 SecA protein signature 356 373 2.2E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 499 1.1E-243 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Gene3D G3DSA:1.10.1200.230 620 703 0.0 T 14-10-2018 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 ProSitePatterns PS01312 SecA family signature. 480 495 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 C2I25_13290 c019a89d588a2fe4173cabea45b40f9d 835 Pfam PF07516 SecA Wing and Scaffold domain 567 776 2.1E-64 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 C2I25_11110 f75f31b3e70d166158d9f97e7fc5657b 357 Pfam PF10635 DisA bacterial checkpoint controller linker region 143 281 8.7E-51 T 14-10-2018 IPR018906 DNA integrity scanning, DisA, linker region C2I25_11110 f75f31b3e70d166158d9f97e7fc5657b 357 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 26 137 1.4E-26 T 14-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal C2I25_11110 f75f31b3e70d166158d9f97e7fc5657b 357 Gene3D G3DSA:1.20.1260.110 144 289 2.9E-46 T 14-10-2018 IPR038331 DisA, linker domain superfamily C2I25_11110 f75f31b3e70d166158d9f97e7fc5657b 357 Gene3D G3DSA:3.40.1700.10 8 143 2.3E-56 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I25_11110 f75f31b3e70d166158d9f97e7fc5657b 357 SUPERFAMILY SSF143597 17 143 2.88E-28 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I25_11110 f75f31b3e70d166158d9f97e7fc5657b 357 Gene3D G3DSA:1.10.150.20 290 351 5.2E-21 T 14-10-2018 C2I25_11110 f75f31b3e70d166158d9f97e7fc5657b 357 SUPERFAMILY SSF47781 241 345 8.53E-13 T 14-10-2018 IPR010994 RuvA domain 2-like C2I25_11110 f75f31b3e70d166158d9f97e7fc5657b 357 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 6 354 44.958 T 14-10-2018 IPR023763 DNA integrity scanning protein, DisA C2I25_22980 0b2436a21896b237a8d3b1346cac1977 351 SUPERFAMILY SSF51735 9 331 2.3E-68 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22980 0b2436a21896b237a8d3b1346cac1977 351 Pfam PF16363 GDP-mannose 4,6 dehydratase 13 321 2.8E-39 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_22980 0b2436a21896b237a8d3b1346cac1977 351 Gene3D G3DSA:3.40.50.720 2 189 8.2E-50 T 14-10-2018 C2I25_22980 0b2436a21896b237a8d3b1346cac1977 351 Gene3D G3DSA:3.90.25.10 190 351 3.7E-60 T 14-10-2018 C2I25_22980 0b2436a21896b237a8d3b1346cac1977 351 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 6 348 3.4E-149 T 14-10-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.3E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.3E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.3E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.3E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 562 2.3E-244 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 SUPERFAMILY SSF55826 218 386 1.31E-33 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 Gene3D G3DSA:3.90.960.10 240 386 2.7E-257 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 2.0E-56 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 Gene3D G3DSA:3.30.930.10 11 462 2.7E-257 T 14-10-2018 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 Gene3D G3DSA:3.40.50.800 4 550 2.7E-257 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 PIRSF PIRSF001535 1 566 2.9E-269 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 Pfam PF03129 Anticodon binding domain 472 563 1.2E-20 T 14-10-2018 IPR004154 Anticodon-binding C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 Pfam PF04073 Aminoacyl-tRNA editing domain 257 374 4.2E-28 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 SUPERFAMILY SSF55681 9 475 7.47E-104 T 14-10-2018 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 41.512 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 C2I25_20415 10bfc8bb4b37d3fc6dbcffa834384ad2 566 SUPERFAMILY SSF52954 460 565 1.15E-30 T 14-10-2018 C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 SMART SM00893 5 195 7.0E-46 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 Pfam PF01012 Electron transfer flavoprotein domain 5 179 4.2E-43 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 SUPERFAMILY SSF52402 4 191 2.58E-50 T 14-10-2018 C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 Gene3D G3DSA:3.40.50.1220 195 325 2.9E-57 T 14-10-2018 C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 Gene3D G3DSA:3.40.50.620 1 194 1.0E-54 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 SUPERFAMILY SSF52467 198 317 2.12E-48 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 PIRSF PIRSF000089 1 323 2.3E-113 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 1.5E-35 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 C2I25_16715 e1a4958bd67b0b19d03738a616c277d9 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 C2I25_03075 76069d3824d3f20da969f42842ec7f45 266 PRINTS PR00207 Flagellin signature 35 52 1.3E-14 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03075 76069d3824d3f20da969f42842ec7f45 266 PRINTS PR00207 Flagellin signature 74 93 1.3E-14 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03075 76069d3824d3f20da969f42842ec7f45 266 PRINTS PR00207 Flagellin signature 109 132 1.3E-14 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03075 76069d3824d3f20da969f42842ec7f45 266 Gene3D G3DSA:1.20.1330.10 48 216 3.7E-44 T 14-10-2018 C2I25_03075 76069d3824d3f20da969f42842ec7f45 266 Pfam PF00700 Bacterial flagellin C-terminal helical region 181 264 2.3E-19 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_03075 76069d3824d3f20da969f42842ec7f45 266 SUPERFAMILY SSF64518 1 265 9.68E-73 T 14-10-2018 C2I25_03075 76069d3824d3f20da969f42842ec7f45 266 Gene3D G3DSA:1.10.8.410 217 265 8.1E-13 T 14-10-2018 C2I25_03075 76069d3824d3f20da969f42842ec7f45 266 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 4.2E-35 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:3.40.50.300 1 203 4.7E-71 T 14-10-2018 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 60.149 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF50447 203 300 1.3E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 3.4E-15 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 4.6E-60 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 9.2E-18 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:2.40.30.10 206 335 1.1E-52 T 14-10-2018 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF52540 6 219 9.26E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.4E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.4E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.4E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.4E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.4E-24 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:2.40.30.10 339 394 9.6E-27 T 14-10-2018 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 3.7E-32 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.4E-230 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I25_10985 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF50465 303 395 1.35E-34 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal C2I25_22230 28104f0a4d2434345d237d872be753db 395 SUPERFAMILY SSF103473 4 394 8.11E-60 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_22230 28104f0a4d2434345d237d872be753db 395 Pfam PF07690 Major Facilitator Superfamily 22 359 8.8E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_22230 28104f0a4d2434345d237d872be753db 395 Gene3D G3DSA:1.20.1250.20 3 193 1.4E-29 T 14-10-2018 C2I25_22230 28104f0a4d2434345d237d872be753db 395 Gene3D G3DSA:1.20.1250.20 202 395 8.3E-23 T 14-10-2018 C2I25_16500 342746e2c0ec1982a875f52d1b691860 254 Pfam PF00588 SpoU rRNA Methylase family 108 245 1.7E-37 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 C2I25_16500 342746e2c0ec1982a875f52d1b691860 254 SMART SM00967 31 99 3.8E-9 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 C2I25_16500 342746e2c0ec1982a875f52d1b691860 254 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 97 3.0E-11 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 C2I25_16500 342746e2c0ec1982a875f52d1b691860 254 Gene3D G3DSA:3.40.1280.10 96 253 2.4E-53 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I25_16500 342746e2c0ec1982a875f52d1b691860 254 SUPERFAMILY SSF55315 3 96 1.04E-24 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_16500 342746e2c0ec1982a875f52d1b691860 254 Gene3D G3DSA:3.30.1330.30 2 95 1.6E-23 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_16500 342746e2c0ec1982a875f52d1b691860 254 SUPERFAMILY SSF75217 105 248 1.67E-43 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I25_12700 10a170e92a8720ce989066d747ba9caf 333 Pfam PF00146 NADH dehydrogenase 23 326 2.0E-124 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12700 10a170e92a8720ce989066d747ba9caf 333 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 15 332 25.055 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12700 10a170e92a8720ce989066d747ba9caf 333 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 Gene3D G3DSA:3.90.780.10 346 553 3.4E-33 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 Pfam PF02872 5'-nucleotidase, C-terminal domain 357 508 2.2E-23 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 PRINTS PR01607 Apyrase family signature 241 264 3.8E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 PRINTS PR01607 Apyrase family signature 268 288 3.8E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 PRINTS PR01607 Apyrase family signature 214 231 3.8E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 PRINTS PR01607 Apyrase family signature 37 55 3.8E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 Gene3D G3DSA:3.60.21.10 30 333 2.5E-78 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 SUPERFAMILY SSF55816 356 569 9.42E-27 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 SUPERFAMILY SSF56300 31 343 3.6E-75 T 14-10-2018 C2I25_25915 120231f218f8f78d7cbac8bfc599074f 650 Pfam PF00149 Calcineurin-like phosphoesterase 40 258 1.4E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_11815 d50b68545d4aadb3728c0102bf3a4f4e 159 PIRSF PIRSF004505 1 159 6.0E-52 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 C2I25_11815 d50b68545d4aadb3728c0102bf3a4f4e 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.048 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 C2I25_11815 d50b68545d4aadb3728c0102bf3a4f4e 159 Gene3D G3DSA:3.40.1280.10 1 159 6.1E-65 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I25_11815 d50b68545d4aadb3728c0102bf3a4f4e 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 1.4E-56 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 C2I25_11815 d50b68545d4aadb3728c0102bf3a4f4e 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 1.9E-67 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 C2I25_11815 d50b68545d4aadb3728c0102bf3a4f4e 159 SUPERFAMILY SSF75217 2 157 4.58E-60 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 SUPERFAMILY SSF56300 52 315 2.81E-36 T 14-10-2018 C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 508 654 2.0E-16 T 14-10-2018 C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 SUPERFAMILY SSF49265 350 444 1.28E-6 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 SUPERFAMILY SSF49899 457 659 1.8E-27 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 Pfam PF00149 Calcineurin-like phosphoesterase 57 248 2.0E-13 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 Gene3D G3DSA:3.60.21.10 33 315 2.7E-34 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 Gene3D G3DSA:1.20.1270.90 670 749 1.2E-8 T 14-10-2018 C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 Gene3D G3DSA:2.60.40.10 347 442 9.8E-8 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_07255 b9d4df2fb43f41fbb4aaa01018143139 824 Gene3D G3DSA:2.60.120.200 443 661 3.4E-25 T 14-10-2018 C2I25_07645 dab547b60ff520b0aff561c1e3c5e840 393 Gene3D G3DSA:1.20.1720.10 9 348 9.9E-77 T 14-10-2018 C2I25_07645 dab547b60ff520b0aff561c1e3c5e840 393 Pfam PF07690 Major Facilitator Superfamily 13 198 3.9E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_07645 dab547b60ff520b0aff561c1e3c5e840 393 Pfam PF07690 Major Facilitator Superfamily 213 380 6.6E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_07645 dab547b60ff520b0aff561c1e3c5e840 393 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 6.7E-7 T 14-10-2018 C2I25_07645 dab547b60ff520b0aff561c1e3c5e840 393 PRINTS PR01036 Tetracycline resistance protein TetB signature 358 378 6.7E-7 T 14-10-2018 C2I25_07645 dab547b60ff520b0aff561c1e3c5e840 393 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 6.7E-7 T 14-10-2018 C2I25_07645 dab547b60ff520b0aff561c1e3c5e840 393 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 6.7E-7 T 14-10-2018 C2I25_07645 dab547b60ff520b0aff561c1e3c5e840 393 SUPERFAMILY SSF103473 5 383 5.62E-71 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_11430 ac960d660881eda7af52f36c6c581b42 291 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 92 103 - T 14-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 C2I25_11430 ac960d660881eda7af52f36c6c581b42 291 SUPERFAMILY SSF53790 12 230 3.14E-82 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I25_11430 ac960d660881eda7af52f36c6c581b42 291 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 14 232 36.35 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 C2I25_11430 ac960d660881eda7af52f36c6c581b42 291 Gene3D G3DSA:3.30.950.10 122 236 3.6E-41 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I25_11430 ac960d660881eda7af52f36c6c581b42 291 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 213 3.5E-28 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I25_11430 ac960d660881eda7af52f36c6c581b42 291 PIRSF PIRSF005917 3 291 4.4E-104 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 C2I25_11430 ac960d660881eda7af52f36c6c581b42 291 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 287 5.9E-81 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 C2I25_11430 ac960d660881eda7af52f36c6c581b42 291 Gene3D G3DSA:3.40.1010.10 1 121 2.4E-48 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I25_15700 e1660f754e76a405cfc3b90fab25e0e8 143 SUPERFAMILY SSF55961 3 143 1.67E-42 T 14-10-2018 C2I25_15700 e1660f754e76a405cfc3b90fab25e0e8 143 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 142 7.8E-12 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like C2I25_15700 e1660f754e76a405cfc3b90fab25e0e8 143 Gene3D G3DSA:3.30.530.20 1 143 1.6E-42 T 14-10-2018 IPR023393 START-like domain superfamily C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 PIRSF PIRSF001553 1 291 9.8E-134 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 1.9E-147 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 Pfam PF02629 CoA binding domain 6 99 1.4E-32 T 14-10-2018 IPR003781 CoA-binding GO:0048037 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 SMART SM00881 4 100 8.7E-37 T 14-10-2018 IPR003781 CoA-binding GO:0048037 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 Gene3D G3DSA:3.40.50.261 124 289 2.3E-71 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.8E-40 T 14-10-2018 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.8E-40 T 14-10-2018 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.8E-40 T 14-10-2018 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.8E-40 T 14-10-2018 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.943 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 Pfam PF00549 CoA-ligase 151 268 5.2E-18 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 SUPERFAMILY SSF52210 123 287 9.03E-55 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 Gene3D G3DSA:3.40.50.720 1 123 1.2E-52 T 14-10-2018 C2I25_20335 36a9d133f07d823f73627e0431f160cf 300 SUPERFAMILY SSF51735 1 122 3.94E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 SMART SM00267 468 640 1.1E-61 T 14-10-2018 IPR000160 GGDEF domain C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 SUPERFAMILY SSF141868 655 904 6.02E-84 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 SMART SM00091 356 422 1.2E-7 T 14-10-2018 IPR000014 PAS domain C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 Gene3D G3DSA:3.20.20.450 654 904 6.3E-92 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 476 637 3.6E-40 T 14-10-2018 IPR000160 GGDEF domain C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 SMART SM00086 427 468 9.2E-4 T 14-10-2018 IPR001610 PAC motif C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 SUPERFAMILY SSF55785 344 466 1.1E-21 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 Gene3D G3DSA:3.30.450.20 353 476 1.5E-21 T 14-10-2018 C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 Pfam PF00563 EAL domain 656 891 3.8E-67 T 14-10-2018 IPR001633 EAL domain C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 SUPERFAMILY SSF55073 484 641 2.35E-47 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 SMART SM00052 650 896 3.5E-107 T 14-10-2018 IPR001633 EAL domain C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 Pfam PF00990 Diguanylate cyclase, GGDEF domain 479 635 9.2E-50 T 14-10-2018 IPR000160 GGDEF domain C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 Pfam PF13426 PAS domain 366 467 1.3E-11 T 14-10-2018 IPR000014 PAS domain C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 Gene3D G3DSA:3.30.70.270 477 653 1.5E-60 T 14-10-2018 C2I25_12675 b3d5ba2ce3aadd13d048b3262d53fc8f 909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 355 474 9.7E-18 T 14-10-2018 IPR000014 PAS domain C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 Pfam PF01022 Bacterial regulatory protein, arsR family 48 93 1.1E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.4E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 1.4E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 73 1.4E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 1.4E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 SUPERFAMILY SSF46785 29 122 4.89E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 SMART SM00418 41 119 8.8E-31 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 64 82 - T 14-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 C2I25_08505 b88d0e10b9a11fe97b92fbe4f6082af1 125 Gene3D G3DSA:1.10.10.10 8 125 2.9E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_05145 e345f3546f5971eeb319078eda302f41 162 SUPERFAMILY SSF55729 5 134 4.87E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_05145 e345f3546f5971eeb319078eda302f41 162 Gene3D G3DSA:3.40.630.30 2 146 1.3E-11 T 14-10-2018 C2I25_05145 e345f3546f5971eeb319078eda302f41 162 Pfam PF00583 Acetyltransferase (GNAT) family 49 134 3.6E-10 T 14-10-2018 IPR000182 GNAT domain C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 2.8E-29 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 SMART SM00357 4 67 1.1E-27 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 PIRSF PIRSF002599 1 67 1.3E-25 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 SUPERFAMILY SSF50249 3 66 5.14E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 14-10-2018 IPR019844 Cold-shock conserved site C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 PRINTS PR00050 Cold shock protein signature 5 20 1.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 PRINTS PR00050 Cold shock protein signature 40 58 1.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 PRINTS PR00050 Cold shock protein signature 25 34 1.4E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_05745 ebbca6b9885bd8a775f826d620bc2984 67 Gene3D G3DSA:2.40.50.140 2 65 1.3E-28 T 14-10-2018 C2I25_12205 004990cd20126f9963cbadf3983c761b 95 ProDom PD705231 YWDI GROUP-SPECIFIC 1 95 1.0E-39 T 14-10-2018 IPR035218 Protein of unknown function DUF5327 C2I25_12205 004990cd20126f9963cbadf3983c761b 95 Pfam PF17261 Family of unknown function (DUF5327) 1 95 1.0E-22 T 14-10-2018 IPR035218 Protein of unknown function DUF5327 C2I25_00205 81a5488100f66f3692824a003189c1b4 633 Gene3D G3DSA:3.60.20.10 7 192 1.9E-64 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_00205 81a5488100f66f3692824a003189c1b4 633 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 6.5E-171 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I25_00205 81a5488100f66f3692824a003189c1b4 633 Pfam PF00733 Asparagine synthase 241 610 8.8E-114 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 C2I25_00205 81a5488100f66f3692824a003189c1b4 633 SUPERFAMILY SSF56235 1 224 3.26E-62 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_00205 81a5488100f66f3692824a003189c1b4 633 Pfam PF13537 Glutamine amidotransferase domain 51 168 4.7E-46 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I25_00205 81a5488100f66f3692824a003189c1b4 633 PIRSF PIRSF001589 1 630 4.1E-196 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I25_00205 81a5488100f66f3692824a003189c1b4 633 SUPERFAMILY SSF52402 231 605 2.0E-90 T 14-10-2018 C2I25_12415 e4df2cfa3de8a51be4285420a5ea7fba 285 Pfam PF01381 Helix-turn-helix 10 60 2.3E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_12415 e4df2cfa3de8a51be4285420a5ea7fba 285 SUPERFAMILY SSF47413 5 64 1.6E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_12415 e4df2cfa3de8a51be4285420a5ea7fba 285 SMART SM00530 9 63 3.0E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_12415 e4df2cfa3de8a51be4285420a5ea7fba 285 SUPERFAMILY SSF48452 158 253 1.4E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_12415 e4df2cfa3de8a51be4285420a5ea7fba 285 Gene3D G3DSA:1.25.40.10 1 285 5.6E-106 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_21425 09dc055efb7285715bc8d620d49d75eb 487 SUPERFAMILY SSF56801 9 481 1.83E-107 T 14-10-2018 C2I25_21425 09dc055efb7285715bc8d620d49d75eb 487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_21425 09dc055efb7285715bc8d620d49d75eb 487 Gene3D G3DSA:3.30.300.310 387 484 2.1E-26 T 14-10-2018 C2I25_21425 09dc055efb7285715bc8d620d49d75eb 487 Pfam PF13193 AMP-binding enzyme C-terminal domain 398 469 5.2E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_21425 09dc055efb7285715bc8d620d49d75eb 487 Gene3D G3DSA:3.40.50.12780 3 386 3.7E-76 T 14-10-2018 C2I25_21425 09dc055efb7285715bc8d620d49d75eb 487 Pfam PF00501 AMP-binding enzyme 9 387 6.6E-64 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_21330 f038a26ff55dc483f5c0db835ee19a56 713 Gene3D G3DSA:3.30.565.10 563 705 8.0E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21330 f038a26ff55dc483f5c0db835ee19a56 713 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 605 699 2.2E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21330 f038a26ff55dc483f5c0db835ee19a56 713 SUPERFAMILY SSF55874 574 698 1.05E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21330 f038a26ff55dc483f5c0db835ee19a56 713 SMART SM00387 603 701 1.0E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_12085 0a10032204c034193a0c2df5882a4d16 238 SUPERFAMILY SSF52172 1 169 1.57E-14 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_12085 0a10032204c034193a0c2df5882a4d16 238 Pfam PF00072 Response regulator receiver domain 5 109 3.4E-7 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12085 0a10032204c034193a0c2df5882a4d16 238 Gene3D G3DSA:2.40.50.1020 130 238 5.5E-14 T 14-10-2018 C2I25_12085 0a10032204c034193a0c2df5882a4d16 238 Pfam PF04397 LytTr DNA-binding domain 138 236 1.6E-27 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_12085 0a10032204c034193a0c2df5882a4d16 238 Gene3D G3DSA:3.40.50.2300 1 129 2.1E-12 T 14-10-2018 C2I25_12085 0a10032204c034193a0c2df5882a4d16 238 SMART SM00448 1 112 0.0042 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12085 0a10032204c034193a0c2df5882a4d16 238 SMART SM00850 136 237 1.4E-29 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 Gene3D G3DSA:3.10.580.10 195 347 4.7E-51 T 14-10-2018 C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF00571 CBS domain 284 338 3.3E-4 T 14-10-2018 IPR000644 CBS domain C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF00571 CBS domain 222 271 1.2E-7 T 14-10-2018 IPR000644 CBS domain C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 SUPERFAMILY SSF54631 204 341 5.94E-33 T 14-10-2018 C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF01595 Domain of unknown function DUF21 8 201 3.2E-48 T 14-10-2018 IPR002550 CNNM, transmembrane domain C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 Gene3D G3DSA:3.30.465.10 348 434 1.3E-14 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF03471 Transporter associated domain 355 429 8.1E-14 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 SMART SM01091 354 431 1.4E-18 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_28545 6bbc51c87ef36900403e7fa34a572c10 451 SUPERFAMILY SSF56176 351 429 2.34E-14 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 Gene3D G3DSA:3.10.580.10 195 347 4.7E-51 T 14-10-2018 C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF00571 CBS domain 284 338 3.3E-4 T 14-10-2018 IPR000644 CBS domain C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF00571 CBS domain 222 271 1.2E-7 T 14-10-2018 IPR000644 CBS domain C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 SUPERFAMILY SSF54631 204 341 5.94E-33 T 14-10-2018 C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF01595 Domain of unknown function DUF21 8 201 3.2E-48 T 14-10-2018 IPR002550 CNNM, transmembrane domain C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 Gene3D G3DSA:3.30.465.10 348 434 1.3E-14 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF03471 Transporter associated domain 355 429 8.1E-14 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 SMART SM01091 354 431 1.4E-18 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_28500 6bbc51c87ef36900403e7fa34a572c10 451 SUPERFAMILY SSF56176 351 429 2.34E-14 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 Gene3D G3DSA:3.10.580.10 195 347 4.7E-51 T 14-10-2018 C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF00571 CBS domain 284 338 3.3E-4 T 14-10-2018 IPR000644 CBS domain C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF00571 CBS domain 222 271 1.2E-7 T 14-10-2018 IPR000644 CBS domain C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 SUPERFAMILY SSF54631 204 341 5.94E-33 T 14-10-2018 C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF01595 Domain of unknown function DUF21 8 201 3.2E-48 T 14-10-2018 IPR002550 CNNM, transmembrane domain C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 Gene3D G3DSA:3.30.465.10 348 434 1.3E-14 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 Pfam PF03471 Transporter associated domain 355 429 8.1E-14 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 SMART SM01091 354 431 1.4E-18 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_00025 6bbc51c87ef36900403e7fa34a572c10 451 SUPERFAMILY SSF56176 351 429 2.34E-14 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_20295 55a3ea6a781956a5b176c020de2a6f73 75 Pfam PF13083 KH domain 2 74 7.6E-23 T 14-10-2018 C2I25_20295 55a3ea6a781956a5b176c020de2a6f73 75 Gene3D G3DSA:3.30.300.20 1 72 2.5E-6 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_20295 55a3ea6a781956a5b176c020de2a6f73 75 SUPERFAMILY SSF54814 15 58 1.96E-7 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I25_20295 55a3ea6a781956a5b176c020de2a6f73 75 Hamap MF_00088 UPF0109 protein . 1 75 21.45 T 14-10-2018 IPR020627 Uncharacterised protein family UPF0109 C2I25_11070 2f296062777f7ebc122bbc900b3fadd9 247 SUPERFAMILY SSF75217 67 243 1.05E-48 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I25_11070 2f296062777f7ebc122bbc900b3fadd9 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 3.6E-22 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 C2I25_11070 2f296062777f7ebc122bbc900b3fadd9 247 Gene3D G3DSA:3.40.1280.10 75 243 2.6E-54 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I25_11070 2f296062777f7ebc122bbc900b3fadd9 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 242 8.8E-83 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 C2I25_11070 2f296062777f7ebc122bbc900b3fadd9 247 Gene3D G3DSA:3.30.1330.30 1 74 9.3E-12 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_11070 2f296062777f7ebc122bbc900b3fadd9 247 SUPERFAMILY SSF55315 3 76 4.0E-18 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_11070 2f296062777f7ebc122bbc900b3fadd9 247 Pfam PF00588 SpoU rRNA Methylase family 96 236 1.8E-38 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 C2I25_11070 2f296062777f7ebc122bbc900b3fadd9 247 SMART SM00967 5 79 5.1E-22 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 C2I25_16335 0083a186b5ed9b5e6e9bd226ae8ea89a 435 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 27 422 1.3E-123 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I25_16335 0083a186b5ed9b5e6e9bd226ae8ea89a 435 SUPERFAMILY SSF53659 6 427 6.84E-142 T 14-10-2018 C2I25_16335 0083a186b5ed9b5e6e9bd226ae8ea89a 435 SMART SM01329 26 423 2.0E-185 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I25_16335 0083a186b5ed9b5e6e9bd226ae8ea89a 435 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 6 428 1.5E-220 T 14-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 C2I25_16335 0083a186b5ed9b5e6e9bd226ae8ea89a 435 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 312 331 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 C2I25_16335 0083a186b5ed9b5e6e9bd226ae8ea89a 435 Gene3D G3DSA:3.40.718.10 2 428 2.9E-182 T 14-10-2018 C2I25_01925 d8310b509579a5046b53b1889e0852af 351 Pfam PF00296 Luciferase-like monooxygenase 27 308 1.1E-43 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I25_01925 d8310b509579a5046b53b1889e0852af 351 Gene3D G3DSA:3.20.20.30 7 351 8.5E-69 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_01925 d8310b509579a5046b53b1889e0852af 351 SUPERFAMILY SSF51679 22 347 3.93E-66 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_20340 db90a97c24a7582369cd8832214032ac 289 SUPERFAMILY SSF102405 80 287 5.26E-33 T 14-10-2018 C2I25_20340 db90a97c24a7582369cd8832214032ac 289 Gene3D G3DSA:3.40.50.450 17 288 3.0E-90 T 14-10-2018 C2I25_20340 db90a97c24a7582369cd8832214032ac 289 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 286 7.6E-71 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 C2I25_20340 db90a97c24a7582369cd8832214032ac 289 Pfam PF02481 DNA recombination-mediator protein A 71 278 2.3E-75 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 SUPERFAMILY SSF55816 371 611 2.49E-42 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 Pfam PF02872 5'-nucleotidase, C-terminal domain 372 568 3.2E-22 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 Pfam PF00149 Calcineurin-like phosphoesterase 40 288 1.7E-12 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 Pfam PF00746 LPXTG cell wall anchor motif 750 784 5.1E-6 T 14-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor C2I25_18830 c700a892baac4e73683908ac484bdcde 786 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 753 783 1.1E-5 T 14-10-2018 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 ProSitePatterns PS00786 5'-nucleotidase signature 2. 131 142 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 PRINTS PR01607 Apyrase family signature 271 294 1.9E-24 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 PRINTS PR01607 Apyrase family signature 242 259 1.9E-24 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 PRINTS PR01607 Apyrase family signature 38 56 1.9E-24 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 PRINTS PR01607 Apyrase family signature 445 468 1.9E-24 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 PRINTS PR01607 Apyrase family signature 548 567 1.9E-24 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 PRINTS PR01607 Apyrase family signature 297 317 1.9E-24 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 Gene3D G3DSA:3.60.21.10 33 370 1.6E-110 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_18830 c700a892baac4e73683908ac484bdcde 786 SUPERFAMILY SSF56300 35 380 3.8E-77 T 14-10-2018 C2I25_18830 c700a892baac4e73683908ac484bdcde 786 Gene3D G3DSA:3.90.780.10 428 610 8.6E-54 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 358 1.0E-28 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 260 7.0E-98 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 Gene3D G3DSA:2.40.30.110 282 364 3.9E-32 T 14-10-2018 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 Gene3D G3DSA:3.30.70.1400 53 138 6.2E-94 T 14-10-2018 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 Gene3D G3DSA:3.30.1360.120 6 237 6.2E-94 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 364 48.658 T 14-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 SUPERFAMILY SSF103025 4 283 1.57E-101 T 14-10-2018 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 364 8.7E-146 T 14-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 Gene3D G3DSA:4.10.1250.10 238 281 6.5E-18 T 14-10-2018 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 PIRSF PIRSF006487 1 366 3.9E-109 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 C2I25_18170 399a30e8c7fabf25eb039f893dcba44f 366 SUPERFAMILY SSF101790 275 364 3.92E-27 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal C2I25_13910 9e0d1724d0673209f82c35df42d3a342 221 Pfam PF00072 Response regulator receiver domain 4 112 1.9E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_13910 9e0d1724d0673209f82c35df42d3a342 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 2.4E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_13910 9e0d1724d0673209f82c35df42d3a342 221 SUPERFAMILY SSF52172 1 179 9.08E-39 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_13910 9e0d1724d0673209f82c35df42d3a342 221 SMART SM00448 2 112 5.6E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_13910 9e0d1724d0673209f82c35df42d3a342 221 Gene3D G3DSA:3.40.50.2300 1 131 1.9E-36 T 14-10-2018 C2I25_13910 9e0d1724d0673209f82c35df42d3a342 221 SMART SM00862 148 219 7.2E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_13910 9e0d1724d0673209f82c35df42d3a342 221 Gene3D G3DSA:1.10.10.10 132 221 1.1E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_14190 abb7ea2181889c4b72f9a984427904fa 430 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 147 420 3.0E-75 T 14-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 C2I25_14190 abb7ea2181889c4b72f9a984427904fa 430 Pfam PF01458 Uncharacterized protein family (UPF0051) 181 404 1.2E-61 T 14-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 C2I25_14190 abb7ea2181889c4b72f9a984427904fa 430 SUPERFAMILY SSF101960 11 429 3.4E-117 T 14-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily C2I25_23150 ae7ae3a37e37bdc80452c3a071e4de18 67 SMART SM00530 6 61 9.9E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_23150 ae7ae3a37e37bdc80452c3a071e4de18 67 Gene3D G3DSA:1.10.260.40 3 67 1.5E-26 T 14-10-2018 C2I25_23150 ae7ae3a37e37bdc80452c3a071e4de18 67 Pfam PF01381 Helix-turn-helix 7 60 3.0E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_23150 ae7ae3a37e37bdc80452c3a071e4de18 67 SUPERFAMILY SSF47413 5 65 8.31E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 SUPERFAMILY SSF52467 191 359 2.91E-58 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 332 3.9E-41 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 Gene3D G3DSA:3.40.50.970 1 184 1.1E-70 T 14-10-2018 C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 Gene3D G3DSA:3.40.50.970 361 539 7.4E-125 T 14-10-2018 C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 Gene3D G3DSA:3.40.50.1220 200 360 7.4E-125 T 14-10-2018 C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 173 3.0E-58 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 SUPERFAMILY SSF52518 4 183 3.77E-62 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 SUPERFAMILY SSF52518 368 561 6.28E-65 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 11 561 5.8E-254 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I25_04420 401aa04c3623ec6e1abb05e74f87d1fd 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 539 9.2E-49 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 32 45 - T 14-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 SMART SM00640 32 451 3.8E-139 T 14-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 SUPERFAMILY SSF49899 333 475 1.11E-25 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 Gene3D G3DSA:2.115.10.20 2 349 2.7E-115 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 SUPERFAMILY SSF75005 23 334 1.13E-112 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 336 476 6.9E-26 T 14-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 Gene3D G3DSA:2.60.120.560 353 487 4.8E-22 T 14-10-2018 C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 32 333 4.2E-105 T 14-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal C2I25_07560 1bac84ada9f38c68baccdc7403184297 491 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 19 461 8.4E-164 T 14-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 C2I25_09830 235f9da42ed2699883be2558c3dcc968 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 74.357 T 14-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 C2I25_09830 235f9da42ed2699883be2558c3dcc968 515 Gene3D G3DSA:3.40.309.10 289 479 1.3E-186 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_09830 235f9da42ed2699883be2558c3dcc968 515 SUPERFAMILY SSF53720 4 511 5.5E-154 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_09830 235f9da42ed2699883be2558c3dcc968 515 Pfam PF00171 Aldehyde dehydrogenase family 50 510 4.2E-154 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_09830 235f9da42ed2699883be2558c3dcc968 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 514 2.9E-249 T 14-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 C2I25_09830 235f9da42ed2699883be2558c3dcc968 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I25_09830 235f9da42ed2699883be2558c3dcc968 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I25_09830 235f9da42ed2699883be2558c3dcc968 515 Gene3D G3DSA:3.40.605.10 39 502 1.3E-186 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_10645 4f1e7096e3c538479f56bc8976041b14 433 Gene3D G3DSA:2.60.40.4170 72 245 2.5E-10 T 14-10-2018 C2I25_10645 4f1e7096e3c538479f56bc8976041b14 433 Pfam PF16781 Domain of unknown function (DUF5068) 71 236 3.3E-14 T 14-10-2018 IPR031888 Protein of unknown function DUF5068 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 Gene3D G3DSA:3.40.50.11610 726 935 9.9E-150 T 14-10-2018 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 PIRSF PIRSF000157 1 939 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 SMART SM00861 590 786 1.2E-42 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 SUPERFAMILY SSF52518 152 522 6.54E-72 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 SUPERFAMILY SSF52518 572 791 5.99E-43 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 935 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 791 937 6.6E-37 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 1 939 23.402 T 14-10-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 Gene3D G3DSA:3.40.50.970 155 526 6.5E-135 T 14-10-2018 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 Pfam PF00676 Dehydrogenase E1 component 223 520 6.2E-63 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 Gene3D G3DSA:3.40.50.12470 548 808 9.9E-150 T 14-10-2018 C2I25_05115 70eb30ed075c476474da2eb74e7f73fa 955 Pfam PF02779 Transketolase, pyrimidine binding domain 589 787 1.1E-54 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_19565 09b20e15f87958a275aae98b5636314b 63 ProDom PD054279 YKZF 7 58 3.0E-8 T 14-10-2018 C2I25_19565 09b20e15f87958a275aae98b5636314b 63 Pfam PF14156 Antirepressor AbbA 1 61 1.8E-29 T 14-10-2018 IPR025446 Antirepressor AbbA C2I25_19965 e96578891391965b0b7dee1559543d6c 384 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 1.0E-45 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 373 39.692 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 SMART SM00864 13 205 1.9E-119 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 Gene3D G3DSA:3.40.50.1440 3 220 3.3E-86 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 5 332 6.9E-139 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 SMART SM00865 207 324 5.7E-52 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 Pfam PF12327 FtsZ family, C-terminal domain 222 316 5.2E-32 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal C2I25_19965 e96578891391965b0b7dee1559543d6c 384 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 SUPERFAMILY SSF55307 204 319 3.43E-43 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 SUPERFAMILY SSF52490 12 208 6.8E-74 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 Gene3D G3DSA:3.30.1330.20 221 326 7.9E-41 T 14-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.5E-52 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.5E-52 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.5E-52 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I25_19965 e96578891391965b0b7dee1559543d6c 384 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.5E-52 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 2887 3064 8.2E-8 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 1182 1310 1.2E-11 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 3210 3244 1.4E-4 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1191 1296 5.9E-9 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 2631 2738 9.8E-10 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 633 766 3.2E-8 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1450 1553 3.5E-8 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 798 903 2.3E-9 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1579 1685 1.7E-10 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 2104 2211 1.4E-7 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1319 1427 8.5E-10 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 2499 2607 1.5E-8 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1059 1165 1.4E-8 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1974 2077 1.4E-9 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 2366 2473 1.7E-8 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1710 1817 5.1E-9 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 2765 2872 6.1E-10 T 14-10-2018 IPR026466 Fimbrial isopeptide formation D2 domain C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF00746 LPXTG cell wall anchor motif 3204 3244 1.0E-4 T 14-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 SUPERFAMILY SSF49401 2776 2881 1.12E-7 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 931 981 8.4E-5 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1713 1765 1.9E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1974 2026 7.9E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2502 2554 2.3E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2369 2421 1.3E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2105 2152 1.6E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1061 1113 2.0E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2238 2290 8.4E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1192 1242 1.4E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1582 1634 3.2E-12 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 799 851 6.6E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1453 1505 7.7E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2633 2685 5.2E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2766 2818 7.5E-5 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2899 2949 9.6E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1322 1374 3.2E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1843 1895 6.6E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 1973 2067 2.7E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 1712 1762 5.0E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 2368 2470 1.3E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 2632 2695 7.1E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 1321 1410 4.2E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 1060 1111 2.9E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 2898 2954 8.6E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 1581 1674 2.2E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 1843 1895 4.4E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 1452 1544 2.7E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Pfam PF01345 Domain of unknown function DUF11 1191 1251 4.8E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 2102 2228 6.5E-11 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 1840 1964 1.7E-10 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 1578 1703 6.6E-13 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 2499 2623 9.8E-12 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 633 788 3.3E-6 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 925 1051 2.6E-10 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 1710 1833 5.8E-12 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 2235 2359 1.6E-11 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 794 920 2.9E-12 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 2366 2491 1.4E-12 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 2630 2755 1.9E-13 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 1058 1181 1.4E-11 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 1450 1571 2.4E-11 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 1318 1442 1.3E-12 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 1969 2095 5.2E-12 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 Gene3D G3DSA:2.60.40.740 2763 2886 3.4E-13 T 14-10-2018 C2I25_14505 1ba64bf7ab29f2d20b2a9bd77038c530 3245 SUPERFAMILY SSF49401 1331 1441 1.76E-5 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_00280 e0496f76a6d4bd44837109eec95cee36 485 Pfam PF00144 Beta-lactamase 13 337 6.1E-62 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_00280 e0496f76a6d4bd44837109eec95cee36 485 Pfam PF11954 Domain of unknown function (DUF3471) 385 481 3.8E-19 T 14-10-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal C2I25_00280 e0496f76a6d4bd44837109eec95cee36 485 Gene3D G3DSA:2.40.128.600 381 467 2.5E-7 T 14-10-2018 C2I25_00280 e0496f76a6d4bd44837109eec95cee36 485 SUPERFAMILY SSF56601 9 352 1.41E-85 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_00280 e0496f76a6d4bd44837109eec95cee36 485 Gene3D G3DSA:3.40.710.10 2 349 1.1E-92 T 14-10-2018 C2I25_07065 ae98c8dbfa3ae8d3ebb9ade784fbda90 265 Gene3D G3DSA:3.40.190.10 42 254 2.9E-72 T 14-10-2018 C2I25_07065 ae98c8dbfa3ae8d3ebb9ade784fbda90 265 SMART SM00062 43 262 2.5E-73 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_07065 ae98c8dbfa3ae8d3ebb9ade784fbda90 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 66 79 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site C2I25_07065 ae98c8dbfa3ae8d3ebb9ade784fbda90 265 SMART SM00079 43 261 8.6E-4 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 C2I25_07065 ae98c8dbfa3ae8d3ebb9ade784fbda90 265 SUPERFAMILY SSF53850 1 262 7.25E-68 T 14-10-2018 C2I25_07065 ae98c8dbfa3ae8d3ebb9ade784fbda90 265 Gene3D G3DSA:3.40.190.10 126 223 2.9E-72 T 14-10-2018 C2I25_07065 ae98c8dbfa3ae8d3ebb9ade784fbda90 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 261 1.3E-61 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 313 2.3E-120 T 14-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 430 752 4.0E-149 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 SUPERFAMILY SSF51726 5 391 2.62E-98 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 757 34.415 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 SUPERFAMILY SSF51726 395 754 1.31E-109 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 Gene3D G3DSA:3.20.20.210 7 523 0.0 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 756 0.0 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 PIRSF PIRSF000382 2 762 0.0 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I25_19470 1fae68eb736218182500b14b85fe0a6b 762 Gene3D G3DSA:3.20.20.210 388 755 0.0 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 3 241 4.6E-92 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 163 338 2.7E-9 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 Gene3D G3DSA:3.40.50.800 362 458 1.8E-31 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 Pfam PF03129 Anticodon binding domain 367 454 1.0E-22 T 14-10-2018 IPR004154 Anticodon-binding C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 402 421 5.9E-53 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 146 158 5.9E-53 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 199 216 5.9E-53 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 323 335 5.9E-53 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 167 184 5.9E-53 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 23 37 5.9E-53 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 216 226 5.9E-53 T 14-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 SUPERFAMILY SSF55681 2 370 2.49E-124 T 14-10-2018 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 SUPERFAMILY SSF52954 354 456 1.36E-33 T 14-10-2018 C2I25_14570 eaa3e0e308ff9c84f88f49a9cf36297c 458 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 1 457 53.009 T 14-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 C2I25_04800 087bf5b2ef91434ff3be176a750f0ebb 333 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_04800 087bf5b2ef91434ff3be176a750f0ebb 333 SUPERFAMILY SSF52540 5 241 6.28E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_04800 087bf5b2ef91434ff3be176a750f0ebb 333 Pfam PF08402 TOBE domain 249 324 2.0E-6 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 C2I25_04800 087bf5b2ef91434ff3be176a750f0ebb 333 SUPERFAMILY SSF50331 245 324 6.8E-6 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I25_04800 087bf5b2ef91434ff3be176a750f0ebb 333 Gene3D G3DSA:3.40.50.300 2 299 6.9E-81 T 14-10-2018 C2I25_04800 087bf5b2ef91434ff3be176a750f0ebb 333 SMART SM00382 29 212 3.0E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_04800 087bf5b2ef91434ff3be176a750f0ebb 333 Pfam PF00005 ABC transporter 20 162 2.2E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_04800 087bf5b2ef91434ff3be176a750f0ebb 333 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 2 248 2.7E-138 T 14-10-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 C2I25_22430 f69fe88ffad23f2fe8d932ee53a76cfe 399 Gene3D G3DSA:1.20.1720.10 9 388 6.2E-89 T 14-10-2018 C2I25_22430 f69fe88ffad23f2fe8d932ee53a76cfe 399 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 386 2.0E-70 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 C2I25_22430 f69fe88ffad23f2fe8d932ee53a76cfe 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_22430 f69fe88ffad23f2fe8d932ee53a76cfe 399 Pfam PF07690 Major Facilitator Superfamily 21 350 5.7E-42 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_22430 f69fe88ffad23f2fe8d932ee53a76cfe 399 SUPERFAMILY SSF103473 6 389 5.23E-57 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_22430 f69fe88ffad23f2fe8d932ee53a76cfe 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 71 93 4.8E-10 T 14-10-2018 C2I25_22430 f69fe88ffad23f2fe8d932ee53a76cfe 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 4.8E-10 T 14-10-2018 C2I25_22430 f69fe88ffad23f2fe8d932ee53a76cfe 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 4.8E-10 T 14-10-2018 C2I25_07155 7253472ca217b8dbcd8c2240ca324d30 192 SUPERFAMILY SSF46689 3 62 1.3E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_07155 7253472ca217b8dbcd8c2240ca324d30 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 9.8E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_07155 7253472ca217b8dbcd8c2240ca324d30 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 9.8E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_07155 7253472ca217b8dbcd8c2240ca324d30 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 48 2.4E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_07155 7253472ca217b8dbcd8c2240ca324d30 192 SUPERFAMILY SSF48498 77 172 1.61E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_07155 7253472ca217b8dbcd8c2240ca324d30 192 Gene3D G3DSA:1.10.357.10 1 190 2.8E-53 T 14-10-2018 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 523 7.2E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 320 366 3.5E-9 T 14-10-2018 IPR039506 SpoOB, alpha-helical domain C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 Gene3D G3DSA:3.30.450.20 204 312 4.3E-22 T 14-10-2018 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 Pfam PF13188 PAS domain 223 276 1.5E-4 T 14-10-2018 IPR000014 PAS domain C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 503 2.1E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 2.1E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 484 2.1E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 470 2.1E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 Gene3D G3DSA:3.30.565.10 383 527 4.4E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 Pfam PF17203 Single cache domain 3 42 172 6.8E-15 T 14-10-2018 IPR033463 Single cache domain 3 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 SUPERFAMILY SSF55890 324 368 1.57E-9 T 14-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 SUPERFAMILY SSF55785 218 309 3.98E-7 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 Gene3D G3DSA:3.30.450.20 33 169 3.0E-27 T 14-10-2018 C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 SUPERFAMILY SSF55874 394 521 1.96E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 SMART SM00091 218 283 7.3E-4 T 14-10-2018 IPR000014 PAS domain C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 SUPERFAMILY SSF103190 42 172 4.71E-26 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_06810 c5d2155e04bcfb8ca5e25dadce91ed49 529 SMART SM00387 417 525 1.1E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_02340 319382182c3abea72314276543600d86 435 SUPERFAMILY SSF51338 4 433 3.05E-32 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_02340 319382182c3abea72314276543600d86 435 Gene3D G3DSA:3.20.20.140 60 352 1.5E-147 T 14-10-2018 C2I25_02340 319382182c3abea72314276543600d86 435 SUPERFAMILY SSF51556 59 358 7.83E-95 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_02340 319382182c3abea72314276543600d86 435 Gene3D G3DSA:2.30.40.10 10 426 1.5E-147 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_02340 319382182c3abea72314276543600d86 435 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 434 44.006 T 14-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 C2I25_02340 319382182c3abea72314276543600d86 435 Pfam PF01979 Amidohydrolase family 56 408 2.2E-74 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 Gene3D G3DSA:3.40.50.720 1 149 3.8E-63 T 14-10-2018 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 Gene3D G3DSA:3.90.110.10 150 310 7.6E-62 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 5.8E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 5.8E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 5.8E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 5.8E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 5.8E-31 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 47.449 T 14-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 8.8E-28 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 4.4E-163 T 14-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 SUPERFAMILY SSF51735 2 147 5.65E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 SUPERFAMILY SSF56327 151 309 6.77E-52 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 PIRSF PIRSF000102 2 311 9.5E-106 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_16340 193c4602f60c756b2c666286c2f57e29 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 3.8E-42 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_01325 dd6a6519b4abccf780294cc12b00e459 384 SUPERFAMILY SSF53187 232 377 8.79E-11 T 14-10-2018 C2I25_01325 dd6a6519b4abccf780294cc12b00e459 384 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 97 372 4.1E-69 T 14-10-2018 IPR010897 Sporulation stage II, protein P C2I25_01325 dd6a6519b4abccf780294cc12b00e459 384 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 173 377 2.6E-72 T 14-10-2018 IPR010897 Sporulation stage II, protein P C2I25_01325 dd6a6519b4abccf780294cc12b00e459 384 Gene3D G3DSA:3.40.630.40 213 380 1.2E-5 T 14-10-2018 C2I25_11320 8875d8cb2d1fadbf6db08196d8c2d09c 102 Gene3D G3DSA:2.60.40.2000 27 84 1.3E-24 T 14-10-2018 IPR038705 YabP superfamily C2I25_11320 8875d8cb2d1fadbf6db08196d8c2d09c 102 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 19 102 2.6E-35 T 14-10-2018 IPR012504 Sporulation protein YabP C2I25_11320 8875d8cb2d1fadbf6db08196d8c2d09c 102 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 18 102 5.0E-34 T 14-10-2018 IPR012504 Sporulation protein YabP C2I25_11320 8875d8cb2d1fadbf6db08196d8c2d09c 102 Pfam PF07873 YabP family 19 84 3.6E-20 T 14-10-2018 IPR022476 Sporulation protein YabP/YqfC C2I25_11320 8875d8cb2d1fadbf6db08196d8c2d09c 102 PIRSF PIRSF011576 1 102 1.6E-58 T 14-10-2018 IPR012504 Sporulation protein YabP C2I25_11335 4fb038c93453677ed6b65e455f549faf 533 Pfam PF01943 Polysaccharide biosynthesis protein 9 307 8.8E-39 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I25_11335 4fb038c93453677ed6b65e455f549faf 533 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 360 510 9.3E-29 T 14-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I25_11335 4fb038c93453677ed6b65e455f549faf 533 PIRSF PIRSF038958 4 527 1.7E-85 T 14-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I25_13825 45833aca8846d0b387a5ec8b1355f479 477 Pfam PF01235 Sodium:alanine symporter family 56 451 2.9E-158 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13825 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 184 202 6.4E-59 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13825 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 348 370 6.4E-59 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13825 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 303 321 6.4E-59 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13825 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 212 231 6.4E-59 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13825 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 94 116 6.4E-59 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13825 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 408 428 6.4E-59 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13825 45833aca8846d0b387a5ec8b1355f479 477 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 439 1.7E-153 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_16065 feb65bd610fcc140fd748b4a2065649d 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_16065 feb65bd610fcc140fd748b4a2065649d 528 Pfam PF00501 AMP-binding enzyme 25 424 6.6E-79 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_16065 feb65bd610fcc140fd748b4a2065649d 528 SUPERFAMILY SSF56801 24 524 1.57E-137 T 14-10-2018 C2I25_16065 feb65bd610fcc140fd748b4a2065649d 528 Gene3D G3DSA:3.40.50.12780 8 420 4.4E-109 T 14-10-2018 C2I25_16065 feb65bd610fcc140fd748b4a2065649d 528 Gene3D G3DSA:3.30.300.310 421 525 4.5E-29 T 14-10-2018 C2I25_16065 feb65bd610fcc140fd748b4a2065649d 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 512 1.7E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_28370 4cccd9235b78283f32ded41f39f92da8 83 Pfam PF13135 Protein of unknown function (DUF3947) 2 83 3.1E-42 T 14-10-2018 IPR025039 Protein of unknown function DUF3947 C2I25_25730 131be2b86bb4ba06340902e4041aa0e8 133 SUPERFAMILY SSF46785 2 129 2.84E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_25730 131be2b86bb4ba06340902e4041aa0e8 133 Gene3D G3DSA:1.10.10.10 1 132 3.2E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25730 131be2b86bb4ba06340902e4041aa0e8 133 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 127 2.1E-38 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type C2I25_25730 131be2b86bb4ba06340902e4041aa0e8 133 Pfam PF02082 Transcriptional regulator 1 83 7.2E-29 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 SUPERFAMILY SSF53850 93 287 1.86E-21 T 14-10-2018 C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 Gene3D G3DSA:1.10.10.10 1 91 8.9E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 SUPERFAMILY SSF46785 4 104 1.24E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 Pfam PF03466 LysR substrate binding domain 93 285 3.2E-22 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.4E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 Gene3D G3DSA:3.40.190.290 92 291 5.8E-18 T 14-10-2018 C2I25_02175 46112590b3a4f0515b19d5f8d7892c9f 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 1.0E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_05595 76d6fba4d64cb365200e29575e3314cf 285 SUPERFAMILY SSF109998 28 164 5.89E-17 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I25_05595 76d6fba4d64cb365200e29575e3314cf 285 Pfam PF13616 PPIC-type PPIASE domain 132 226 1.3E-24 T 14-10-2018 C2I25_05595 76d6fba4d64cb365200e29575e3314cf 285 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 281 21.571 T 14-10-2018 IPR023059 Foldase protein PrsA GO:0003755 C2I25_05595 76d6fba4d64cb365200e29575e3314cf 285 Gene3D G3DSA:3.10.50.40 127 248 3.5E-35 T 14-10-2018 C2I25_05595 76d6fba4d64cb365200e29575e3314cf 285 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 163 184 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 C2I25_05595 76d6fba4d64cb365200e29575e3314cf 285 SUPERFAMILY SSF54534 123 224 1.18E-31 T 14-10-2018 C2I25_01050 aa99e9c4959c11a4d464c540e311b15c 491 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 357 436 9.0E-29 T 14-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 C2I25_01050 aa99e9c4959c11a4d464c540e311b15c 491 SUPERFAMILY SSF54862 2 489 6.91E-165 T 14-10-2018 C2I25_01050 aa99e9c4959c11a4d464c540e311b15c 491 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 486 1.3E-276 T 14-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 C2I25_01050 aa99e9c4959c11a4d464c540e311b15c 491 Pfam PF13247 4Fe-4S dicluster domain 173 270 3.2E-37 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_01050 aa99e9c4959c11a4d464c540e311b15c 491 Gene3D G3DSA:1.10.3650.10 357 435 3.5E-27 T 14-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 C2I25_01050 aa99e9c4959c11a4d464c540e311b15c 491 Gene3D G3DSA:3.30.70.20 1 303 3.1E-98 T 14-10-2018 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 SMART SM00304 303 355 1.1E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 SMART SM00304 579 656 94.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 SUPERFAMILY SSF58104 323 659 2.62E-77 T 14-10-2018 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 Gene3D G3DSA:3.30.450.20 64 273 1.1E-38 T 14-10-2018 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 Pfam PF02743 Cache domain 47 264 4.2E-29 T 14-10-2018 IPR033479 Double Cache domain 1 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 Pfam PF00672 HAMP domain 304 351 7.7E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 Gene3D G3DSA:1.10.287.950 369 659 3.0E-69 T 14-10-2018 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 SUPERFAMILY SSF103190 89 190 1.1E-8 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 SMART SM00283 363 659 1.5E-78 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 Gene3D G3DSA:1.10.8.500 302 354 4.3E-12 T 14-10-2018 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 430 610 1.9E-51 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_01575 7a611c2edc7b60ca6eb8af45e8c99b1e 660 Gene3D G3DSA:3.30.450.20 76 183 1.1E-38 T 14-10-2018 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 Gene3D G3DSA:3.40.50.720 3 89 1.2E-20 T 14-10-2018 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 Gene3D G3DSA:3.40.1190.10 91 292 2.1E-53 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 35.303 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 SUPERFAMILY SSF53244 294 428 2.01E-35 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 Pfam PF01225 Mur ligase family, catalytic domain 4 101 3.0E-22 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 Gene3D G3DSA:3.90.190.20 293 436 1.1E-40 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 Pfam PF08245 Mur ligase middle domain 106 275 1.6E-23 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 SUPERFAMILY SSF53623 87 293 2.62E-58 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 SUPERFAMILY SSF51984 4 88 5.89E-20 T 14-10-2018 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 378 3.4E-18 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I25_15820 bb3c9d7715a0110397c9c9a171715ae5 436 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 425 1.3E-134 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10510 e46e844d59ca961f54cdda849f22eda9 224 SUPERFAMILY SSF161098 6 217 2.75E-48 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10510 e46e844d59ca961f54cdda849f22eda9 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 222 7.5E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_10510 e46e844d59ca961f54cdda849f22eda9 224 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 220 1.8E-79 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 C2I25_10510 e46e844d59ca961f54cdda849f22eda9 224 Gene3D G3DSA:1.10.3720.10 1 222 3.2E-55 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_21375 a6947d462595d4649c48a73e8565a08c 244 Gene3D G3DSA:3.40.50.300 1 244 4.5E-61 T 14-10-2018 C2I25_21375 a6947d462595d4649c48a73e8565a08c 244 Pfam PF00005 ABC transporter 23 167 5.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21375 a6947d462595d4649c48a73e8565a08c 244 SUPERFAMILY SSF52540 4 232 4.78E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21375 a6947d462595d4649c48a73e8565a08c 244 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_21375 a6947d462595d4649c48a73e8565a08c 244 SMART SM00382 31 215 1.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_17295 33465c0856648347d2cf1422f7199977 371 Pfam PF03054 tRNA methyl transferase 9 357 1.9E-145 T 14-10-2018 C2I25_17295 33465c0856648347d2cf1422f7199977 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 357 2.6E-138 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 C2I25_17295 33465c0856648347d2cf1422f7199977 371 SUPERFAMILY SSF52402 7 244 6.4E-59 T 14-10-2018 C2I25_17295 33465c0856648347d2cf1422f7199977 371 Gene3D G3DSA:2.40.30.10 279 370 9.9E-30 T 14-10-2018 C2I25_17295 33465c0856648347d2cf1422f7199977 371 Gene3D G3DSA:2.30.30.280 214 277 1.2E-22 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 C2I25_17295 33465c0856648347d2cf1422f7199977 371 Gene3D G3DSA:3.40.50.620 1 213 2.5E-98 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_17295 33465c0856648347d2cf1422f7199977 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 358 40.474 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 C2I25_05345 5e12669365f69233f02c2f03daa8b279 365 SUPERFAMILY SSF48452 196 347 1.06E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_05345 5e12669365f69233f02c2f03daa8b279 365 Gene3D G3DSA:1.25.40.10 186 262 6.4E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_05345 5e12669365f69233f02c2f03daa8b279 365 Gene3D G3DSA:3.90.550.10 2 184 9.0E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_05345 5e12669365f69233f02c2f03daa8b279 365 Pfam PF13176 Tetratricopeptide repeat 235 258 0.018 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_05345 5e12669365f69233f02c2f03daa8b279 365 Pfam PF00535 Glycosyl transferase family 2 10 147 8.0E-18 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_05345 5e12669365f69233f02c2f03daa8b279 365 Pfam PF13181 Tetratricopeptide repeat 269 295 9.9E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_05345 5e12669365f69233f02c2f03daa8b279 365 SUPERFAMILY SSF53448 8 160 2.81E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_05345 5e12669365f69233f02c2f03daa8b279 365 Gene3D G3DSA:1.25.40.10 266 364 4.8E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_22275 ecf1386c8b3914137f7824c715e7d4bb 595 Pfam PF01432 Peptidase family M3 203 582 1.3E-67 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 C2I25_22275 ecf1386c8b3914137f7824c715e7d4bb 595 SUPERFAMILY SSF55486 6 579 2.75E-115 T 14-10-2018 C2I25_22275 ecf1386c8b3914137f7824c715e7d4bb 595 Gene3D G3DSA:1.10.287.830 180 225 1.2E-14 T 14-10-2018 C2I25_22275 ecf1386c8b3914137f7824c715e7d4bb 595 Gene3D G3DSA:1.20.140.70 25 178 2.5E-42 T 14-10-2018 C2I25_22275 ecf1386c8b3914137f7824c715e7d4bb 595 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 10 593 1.5E-180 T 14-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 C2I25_22275 ecf1386c8b3914137f7824c715e7d4bb 595 Pfam PF08439 Oligopeptidase F 114 182 5.5E-18 T 14-10-2018 IPR013647 Oligopeptidase F, N-terminal domain C2I25_22275 ecf1386c8b3914137f7824c715e7d4bb 595 Gene3D G3DSA:1.10.1370.20 227 595 2.2E-128 T 14-10-2018 C2I25_24180 7d83605744a3bd88111d8f00c8ff105f 195 SUPERFAMILY SSF55729 2 173 1.26E-39 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24180 7d83605744a3bd88111d8f00c8ff105f 195 Gene3D G3DSA:3.40.630.30 1 189 4.7E-45 T 14-10-2018 C2I25_24180 7d83605744a3bd88111d8f00c8ff105f 195 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 3.1E-19 T 14-10-2018 IPR000182 GNAT domain C2I25_22300 6639ec087908cf436800ab25f0b5c9cd 174 Gene3D G3DSA:3.40.630.30 1 174 1.8E-44 T 14-10-2018 C2I25_22300 6639ec087908cf436800ab25f0b5c9cd 174 Pfam PF13527 Acetyltransferase (GNAT) domain 4 132 3.7E-10 T 14-10-2018 C2I25_22300 6639ec087908cf436800ab25f0b5c9cd 174 SUPERFAMILY SSF55729 1 138 5.05E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27375 1e6c3c48f6757bf5496b0856e351e8dc 326 SUPERFAMILY SSF56601 15 326 1.31E-118 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_27375 1e6c3c48f6757bf5496b0856e351e8dc 326 Pfam PF04960 Glutaminase 31 326 2.3E-107 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I25_27375 1e6c3c48f6757bf5496b0856e351e8dc 326 Hamap MF_00313 Glutaminase [glsA]. 13 326 44.979 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I25_27375 1e6c3c48f6757bf5496b0856e351e8dc 326 Gene3D G3DSA:3.40.710.10 44 326 7.3E-123 T 14-10-2018 C2I25_27375 1e6c3c48f6757bf5496b0856e351e8dc 326 TIGRFAM TIGR03814 Gln_ase: glutaminase A 17 326 2.2E-121 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I25_27375 1e6c3c48f6757bf5496b0856e351e8dc 326 Gene3D G3DSA:1.10.1500.10 70 207 7.3E-123 T 14-10-2018 C2I25_11305 ab46386bdbc2eca4073eb994aa2be081 161 Gene3D G3DSA:2.40.50.140 1 84 1.4E-29 T 14-10-2018 C2I25_11305 ab46386bdbc2eca4073eb994aa2be081 161 Pfam PF00575 S1 RNA binding domain 4 74 3.4E-22 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_11305 ab46386bdbc2eca4073eb994aa2be081 161 SMART SM00316 4 74 6.8E-27 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_11305 ab46386bdbc2eca4073eb994aa2be081 161 SUPERFAMILY SSF50249 4 81 1.39E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_04270 8286a2780cdac5812c2eac0054645de3 251 Pfam PF01903 CbiX 9 110 2.5E-26 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 C2I25_04270 8286a2780cdac5812c2eac0054645de3 251 Pfam PF01903 CbiX 133 232 1.9E-20 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 C2I25_04270 8286a2780cdac5812c2eac0054645de3 251 SUPERFAMILY SSF53800 1 239 3.05E-43 T 14-10-2018 C2I25_04270 8286a2780cdac5812c2eac0054645de3 251 Gene3D G3DSA:3.40.50.1400 124 240 3.9E-19 T 14-10-2018 C2I25_04270 8286a2780cdac5812c2eac0054645de3 251 Gene3D G3DSA:3.40.50.1400 1 114 3.2E-21 T 14-10-2018 C2I25_00505 1ca8f6f85f172559fb919638a2105047 258 SUPERFAMILY SSF53335 2 256 1.61E-55 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_00505 1ca8f6f85f172559fb919638a2105047 258 Gene3D G3DSA:3.40.50.150 71 255 4.4E-41 T 14-10-2018 C2I25_00505 1ca8f6f85f172559fb919638a2105047 258 Pfam PF04445 Putative SAM-dependent methyltransferase 42 250 1.3E-16 T 14-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 C2I25_12030 2b92c64a6740cad9ec21d5bec76bb2fd 470 Pfam PF01943 Polysaccharide biosynthesis protein 6 267 6.2E-14 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I25_12030 2b92c64a6740cad9ec21d5bec76bb2fd 470 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 324 448 3.4E-9 T 14-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:3.30.559.30 12 253 1.5E-22 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 SUPERFAMILY SSF52777 868 1030 1.67E-40 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 SUPERFAMILY SSF56801 1273 1831 1.27E-149 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:3.40.50.12780 254 666 3.8E-119 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:3.40.50.12780 1300 1702 2.0E-126 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 SUPERFAMILY SSF52777 1036 1283 1.67E-50 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:3.30.559.10 866 1224 2.4E-124 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Pfam PF00501 AMP-binding enzyme 268 672 3.4E-91 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Pfam PF00501 AMP-binding enzyme 1315 1707 1.3E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Pfam PF00668 Condensation domain 863 1294 1.6E-104 T 14-10-2018 IPR001242 Condensation domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Pfam PF00668 Condensation domain 6 246 1.7E-11 T 14-10-2018 IPR001242 Condensation domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 PRINTS PR00154 AMP-binding signature 1461 1469 4.5E-5 T 14-10-2018 IPR020459 AMP-binding C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 PRINTS PR00154 AMP-binding signature 1449 1460 4.5E-5 T 14-10-2018 IPR020459 AMP-binding C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:1.10.1200.10 767 853 7.9E-22 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:1.10.1200.10 1806 1889 4.8E-22 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:3.30.559.30 1034 1279 2.4E-124 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 ProSitePatterns PS00455 Putative AMP-binding domain signature. 411 422 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Pfam PF00550 Phosphopantetheine attachment site 1821 1882 2.0E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Pfam PF00550 Phosphopantetheine attachment site 782 845 3.8E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:3.30.300.30 1703 1805 9.1E-30 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 SUPERFAMILY SSF52777 13 252 8.78E-18 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 SUPERFAMILY SSF47336 772 845 1.11E-16 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 SUPERFAMILY SSF56801 227 793 1.24E-140 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Pfam PF13193 AMP-binding enzyme C-terminal domain 680 753 2.0E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Pfam PF13193 AMP-binding enzyme C-terminal domain 1716 1789 4.6E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 Gene3D G3DSA:3.30.300.30 667 766 4.6E-29 T 14-10-2018 C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 SUPERFAMILY SSF47336 1810 1883 1.57E-17 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 289 696 3.2E-120 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1336 1732 1.4E-127 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_02070 169a97b130f920c3c1915f591d4f7978 1922 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1454 1465 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_04330 46cbbb1e00befc451b646d1e511250fa 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 284 2.1E-59 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I25_04330 46cbbb1e00befc451b646d1e511250fa 323 Gene3D G3DSA:3.40.50.720 3 311 1.1E-120 T 14-10-2018 C2I25_04330 46cbbb1e00befc451b646d1e511250fa 323 Gene3D G3DSA:3.40.50.720 96 285 1.1E-120 T 14-10-2018 C2I25_04330 46cbbb1e00befc451b646d1e511250fa 323 SUPERFAMILY SSF51735 98 284 1.01E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_04330 46cbbb1e00befc451b646d1e511250fa 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 316 2.9E-35 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 C2I25_04330 46cbbb1e00befc451b646d1e511250fa 323 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site C2I25_04330 46cbbb1e00befc451b646d1e511250fa 323 SUPERFAMILY SSF52283 3 136 1.04E-34 T 14-10-2018 C2I25_18175 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 PIRSF PIRSF006815 3 447 6.7E-194 T 14-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 C2I25_18175 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 Gene3D G3DSA:3.90.1150.10 73 442 1.7E-169 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_18175 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 Pfam PF02347 Glycine cleavage system P-protein 3 442 7.4E-164 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 C2I25_18175 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 SUPERFAMILY SSF53383 3 445 1.88E-120 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_18175 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 Gene3D G3DSA:3.40.640.10 84 349 1.7E-169 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_18175 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 51.776 T 14-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 C2I25_21620 10bda7355be43f2e0928d63be8403289 345 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 97 253 1.2E-39 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_21620 10bda7355be43f2e0928d63be8403289 345 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 98 253 4.1E-33 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_21620 10bda7355be43f2e0928d63be8403289 345 Gene3D G3DSA:1.10.260.150 56 345 2.1E-75 T 14-10-2018 C2I25_19365 86734a9162318d55962342d7ae47ab9a 241 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 151 196 2.8E-7 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_19365 86734a9162318d55962342d7ae47ab9a 241 Gene3D G3DSA:3.40.50.300 109 216 1.5E-9 T 14-10-2018 C2I25_19365 86734a9162318d55962342d7ae47ab9a 241 SMART SM00382 39 208 1.3E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_19365 86734a9162318d55962342d7ae47ab9a 241 Gene3D G3DSA:3.40.50.300 15 108 8.6E-10 T 14-10-2018 C2I25_19365 86734a9162318d55962342d7ae47ab9a 241 Pfam PF13476 AAA domain 34 93 3.3E-10 T 14-10-2018 IPR038729 Rad50/SbcC-type AAA domain C2I25_19365 86734a9162318d55962342d7ae47ab9a 241 SUPERFAMILY SSF52540 34 213 6.08E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 PIRSF PIRSF000429 1 391 1.0E-132 T 14-10-2018 IPR002155 Thiolase GO:0016747 C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 Pfam PF00108 Thiolase, N-terminal domain 4 261 1.7E-89 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 1.4E-147 T 14-10-2018 IPR002155 Thiolase GO:0016747 C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 SUPERFAMILY SSF53901 3 268 4.1E-85 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 Gene3D G3DSA:3.40.47.10 126 388 5.0E-167 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 Gene3D G3DSA:3.40.47.10 5 274 5.0E-167 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 Pfam PF02803 Thiolase, C-terminal domain 269 389 7.2E-47 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I25_19360 49abaa2a67b039b4322529308a5669b9 391 SUPERFAMILY SSF53901 269 389 5.35E-41 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_25625 8cabe4ae4dd9443ab7374a3a9be0eb1d 228 Gene3D G3DSA:1.10.1740.10 13 88 3.0E-8 T 14-10-2018 C2I25_25625 8cabe4ae4dd9443ab7374a3a9be0eb1d 228 SUPERFAMILY SSF88946 22 81 7.85E-9 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_25625 8cabe4ae4dd9443ab7374a3a9be0eb1d 228 Pfam PF08281 Sigma-70, region 4 109 160 5.4E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_25625 8cabe4ae4dd9443ab7374a3a9be0eb1d 228 Gene3D G3DSA:1.10.10.10 104 166 9.3E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25625 8cabe4ae4dd9443ab7374a3a9be0eb1d 228 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 161 4.1E-15 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_25625 8cabe4ae4dd9443ab7374a3a9be0eb1d 228 Pfam PF04542 Sigma-70 region 2 24 84 8.6E-6 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_25625 8cabe4ae4dd9443ab7374a3a9be0eb1d 228 SUPERFAMILY SSF88659 101 166 5.79E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_00380 ffba50caa8ff98c517526532ca02294e 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 2.3E-12 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_00380 ffba50caa8ff98c517526532ca02294e 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 2.3E-12 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_00380 ffba50caa8ff98c517526532ca02294e 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 2.3E-12 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_00380 ffba50caa8ff98c517526532ca02294e 446 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_00380 ffba50caa8ff98c517526532ca02294e 446 Pfam PF00209 Sodium:neurotransmitter symporter family 5 122 5.9E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_00380 ffba50caa8ff98c517526532ca02294e 446 Pfam PF00209 Sodium:neurotransmitter symporter family 136 441 5.1E-30 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_00380 ffba50caa8ff98c517526532ca02294e 446 SUPERFAMILY SSF161070 5 443 1.57E-131 T 14-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 C2I25_27660 5798b80d023037ace348d586bdabcf19 458 SUPERFAMILY SSF52540 73 360 3.82E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_27660 5798b80d023037ace348d586bdabcf19 458 Pfam PF00270 DEAD/DEAH box helicase 29 196 7.6E-51 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_27660 5798b80d023037ace348d586bdabcf19 458 SMART SM00487 24 222 6.2E-62 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_27660 5798b80d023037ace348d586bdabcf19 458 SMART SM00490 258 339 2.7E-34 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_27660 5798b80d023037ace348d586bdabcf19 458 Gene3D G3DSA:3.40.50.300 210 453 4.6E-52 T 14-10-2018 C2I25_27660 5798b80d023037ace348d586bdabcf19 458 Pfam PF00271 Helicase conserved C-terminal domain 241 339 8.8E-30 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_27660 5798b80d023037ace348d586bdabcf19 458 Gene3D G3DSA:3.40.50.300 5 209 1.5E-74 T 14-10-2018 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 Gene3D G3DSA:1.25.40.10 780 886 8.4E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 Pfam PF00069 Protein kinase domain 36 234 9.0E-12 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 Gene3D G3DSA:1.25.40.10 667 777 1.1E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SUPERFAMILY SSF56112 36 240 1.08E-15 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 Gene3D G3DSA:1.10.510.10 34 308 2.2E-14 T 14-10-2018 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SUPERFAMILY SSF48452 537 665 1.26E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SUPERFAMILY SSF81901 647 870 2.17E-18 T 14-10-2018 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SMART SM00028 803 836 0.88 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SMART SM00028 602 635 15.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SMART SM00028 676 709 16.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SMART SM00028 756 795 200.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SMART SM00028 837 870 90.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 SMART SM00028 565 598 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 Pfam PF13432 Tetratricopeptide repeat 569 632 2.1E-4 T 14-10-2018 C2I25_00425 be32031785a3bfa1e00a5efb20ac4027 890 Gene3D G3DSA:1.25.40.10 526 666 1.7E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 889 1131 3.7E-51 T 14-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 PIRSF PIRSF000381 1 1132 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 SMART SM01018 618 701 3.4E-38 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Gene3D G3DSA:3.20.20.330 1 314 4.7E-110 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Pfam PF00809 Pterin binding enzyme 334 567 4.3E-40 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Gene3D G3DSA:3.20.20.20 315 610 8.3E-106 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Pfam PF02310 B12 binding domain 707 796 3.7E-21 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 SUPERFAMILY SSF47644 617 700 6.28E-24 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Gene3D G3DSA:1.10.1240.10 611 698 1.7E-26 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Gene3D G3DSA:3.40.50.280 703 853 1.8E-46 T 14-10-2018 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Pfam PF02607 B12 binding domain 621 694 2.9E-22 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 SUPERFAMILY SSF56507 865 1131 3.4E-83 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 SUPERFAMILY SSF51717 331 596 9.55E-80 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 SUPERFAMILY SSF82282 2 373 4.45E-111 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Gene3D G3DSA:3.10.196.10 873 1131 1.9E-57 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Gene3D G3DSA:1.10.288.10 885 941 1.9E-57 T 14-10-2018 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 Pfam PF02574 Homocysteine S-methyltransferase 13 299 8.1E-76 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 TIGRFAM TIGR02082 metH: methionine synthase 8 1131 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_18020 64a5978ede8df3857424c662e13c1160 1132 SUPERFAMILY SSF52242 702 842 6.8E-39 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I25_09190 86b3512418163ddb37b2650855c7bab8 375 Pfam PF13353 4Fe-4S single cluster domain 41 119 8.9E-7 T 14-10-2018 C2I25_09190 86b3512418163ddb37b2650855c7bab8 375 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 9 370 3.1E-192 T 14-10-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB C2I25_09190 86b3512418163ddb37b2650855c7bab8 375 SUPERFAMILY SSF102114 34 329 3.79E-26 T 14-10-2018 C2I25_09190 86b3512418163ddb37b2650855c7bab8 375 Pfam PF08756 YfkB-like domain 221 370 7.0E-75 T 14-10-2018 IPR014866 YfkB-like domain C2I25_09190 86b3512418163ddb37b2650855c7bab8 375 Pfam PF04055 Radical SAM superfamily 37 175 1.6E-10 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_09190 86b3512418163ddb37b2650855c7bab8 375 Gene3D G3DSA:3.20.20.70 28 341 2.1E-22 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_13150 eb824834e6e5524522c6b68f7c9dcd67 405 SUPERFAMILY SSF118215 7 392 6.93E-84 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_13150 eb824834e6e5524522c6b68f7c9dcd67 405 PRINTS PR00173 Glutamate-aspartate symporter signature 182 201 8.0E-16 T 14-10-2018 C2I25_13150 eb824834e6e5524522c6b68f7c9dcd67 405 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 8.0E-16 T 14-10-2018 C2I25_13150 eb824834e6e5524522c6b68f7c9dcd67 405 PRINTS PR00173 Glutamate-aspartate symporter signature 284 310 8.0E-16 T 14-10-2018 C2I25_13150 eb824834e6e5524522c6b68f7c9dcd67 405 PRINTS PR00173 Glutamate-aspartate symporter signature 135 157 8.0E-16 T 14-10-2018 C2I25_13150 eb824834e6e5524522c6b68f7c9dcd67 405 PRINTS PR00173 Glutamate-aspartate symporter signature 347 367 8.0E-16 T 14-10-2018 C2I25_13150 eb824834e6e5524522c6b68f7c9dcd67 405 Pfam PF00375 Sodium:dicarboxylate symporter family 10 392 1.1E-95 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I25_13150 eb824834e6e5524522c6b68f7c9dcd67 405 Gene3D G3DSA:1.10.3860.10 1 397 1.7E-80 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_20700 83d9d54afbb57fbb512db2221d23d264 445 SUPERFAMILY SSF51905 1 442 1.71E-24 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_20700 83d9d54afbb57fbb512db2221d23d264 445 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 34 1.1E-4 T 14-10-2018 C2I25_20700 83d9d54afbb57fbb512db2221d23d264 445 Gene3D G3DSA:3.50.50.60 104 218 3.2E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_20700 83d9d54afbb57fbb512db2221d23d264 445 PIRSF PIRSF038984 122 443 3.7E-12 T 14-10-2018 IPR028348 FAD dependent protein C2I25_20700 83d9d54afbb57fbb512db2221d23d264 445 PIRSF PIRSF038984 2 100 0.012 T 14-10-2018 IPR028348 FAD dependent protein C2I25_20700 83d9d54afbb57fbb512db2221d23d264 445 Gene3D G3DSA:3.50.50.60 1 102 3.5E-12 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 244 9.7E-91 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.3E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.3E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.3E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.3E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.3E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.3E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 SUPERFAMILY SSF51735 5 244 2.35E-88 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 Gene3D G3DSA:3.40.50.720 2 246 6.0E-90 T 14-10-2018 C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 0.0074 T 14-10-2018 C2I25_21805 406035192f4c17b53dcfa7bd0e059927 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 1.5E-73 T 14-10-2018 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 SUPERFAMILY SSF50341 7 150 1.44E-34 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 SMART SM00260 13 149 1.5E-29 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 SMART SM00448 174 297 9.0E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 Gene3D G3DSA:2.40.50.180 34 149 3.3E-34 T 14-10-2018 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 Pfam PF00072 Response regulator receiver domain 176 296 4.7E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 Gene3D G3DSA:3.40.50.2300 168 302 1.1E-23 T 14-10-2018 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 Pfam PF01584 CheW-like domain 18 149 4.1E-36 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 Gene3D G3DSA:2.30.30.40 19 143 3.3E-34 T 14-10-2018 C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 PIRSF PIRSF002867 1 302 1.8E-94 T 14-10-2018 IPR024181 Chemotaxis response regulator CheV C2I25_03085 c59f30705ac12442f96c595aa03c63bb 302 SUPERFAMILY SSF52172 173 300 2.28E-23 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_08800 3b0ce688696d5cec0104abb49158b25c 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.842 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_08800 3b0ce688696d5cec0104abb49158b25c 239 Gene3D G3DSA:1.10.10.200 2 79 3.7E-24 T 14-10-2018 IPR017856 Integrase-like, N-terminal C2I25_08800 3b0ce688696d5cec0104abb49158b25c 239 Pfam PF01709 Transcriptional regulator 4 235 1.6E-80 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_08800 3b0ce688696d5cec0104abb49158b25c 239 Gene3D G3DSA:3.30.70.980 131 201 2.9E-44 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_08800 3b0ce688696d5cec0104abb49158b25c 239 Gene3D G3DSA:3.30.70.980 83 234 2.9E-44 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_08800 3b0ce688696d5cec0104abb49158b25c 239 SUPERFAMILY SSF75625 1 238 4.32E-80 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_08800 3b0ce688696d5cec0104abb49158b25c 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 4.8E-71 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_08800 3b0ce688696d5cec0104abb49158b25c 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 55.025 T 14-10-2018 IPR026562 Probable transcriptional regulatory protein YeeN C2I25_21920 9c13e68ab62eea71e6ef342889afb39c 172 SUPERFAMILY SSF55729 3 154 4.96E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_21920 9c13e68ab62eea71e6ef342889afb39c 172 Gene3D G3DSA:3.40.630.30 13 152 3.5E-22 T 14-10-2018 C2I25_21920 9c13e68ab62eea71e6ef342889afb39c 172 Pfam PF13302 Acetyltransferase (GNAT) domain 21 150 1.0E-11 T 14-10-2018 IPR000182 GNAT domain C2I25_27625 bcf96c0d7bcf61e92907c9b0540f8d1e 367 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 62 116 2.9E-10 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I25_27625 bcf96c0d7bcf61e92907c9b0540f8d1e 367 Gene3D G3DSA:1.10.443.10 160 363 1.3E-55 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_27625 bcf96c0d7bcf61e92907c9b0540f8d1e 367 Pfam PF14657 Arm DNA-binding domain 15 54 7.7E-10 T 14-10-2018 IPR028259 AP2-like integrase, N-terminal domain C2I25_27625 bcf96c0d7bcf61e92907c9b0540f8d1e 367 Gene3D G3DSA:1.10.150.130 60 159 9.7E-22 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I25_27625 bcf96c0d7bcf61e92907c9b0540f8d1e 367 SUPERFAMILY SSF56349 61 358 2.88E-69 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_27625 bcf96c0d7bcf61e92907c9b0540f8d1e 367 Pfam PF00589 Phage integrase family 170 350 5.6E-30 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_17475 018c5dcf7ea63f4dc13388332ba19e9b 181 Pfam PF07883 Cupin domain 102 169 8.8E-13 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_17475 018c5dcf7ea63f4dc13388332ba19e9b 181 SMART SM00530 6 61 5.0E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_17475 018c5dcf7ea63f4dc13388332ba19e9b 181 Gene3D G3DSA:1.10.260.40 1 89 4.0E-17 T 14-10-2018 C2I25_17475 018c5dcf7ea63f4dc13388332ba19e9b 181 Gene3D G3DSA:2.60.120.10 90 180 9.1E-15 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_17475 018c5dcf7ea63f4dc13388332ba19e9b 181 SUPERFAMILY SSF47413 1 66 2.76E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_17475 018c5dcf7ea63f4dc13388332ba19e9b 181 SUPERFAMILY SSF51182 54 171 7.36E-22 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_17475 018c5dcf7ea63f4dc13388332ba19e9b 181 Pfam PF12844 Helix-turn-helix domain 4 62 3.3E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_01440 a38ecf608de31e2fd4295910420afdae 205 Gene3D G3DSA:3.90.79.10 41 205 7.3E-48 T 14-10-2018 C2I25_01440 a38ecf608de31e2fd4295910420afdae 205 SUPERFAMILY SSF55811 22 200 2.17E-28 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_01440 a38ecf608de31e2fd4295910420afdae 205 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 4 58 1.5E-26 T 14-10-2018 C2I25_01440 a38ecf608de31e2fd4295910420afdae 205 Pfam PF00293 NUDIX domain 72 177 2.4E-11 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 SUPERFAMILY SSF81333 2 71 6.28E-21 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Gene3D G3DSA:1.20.20.10 1 72 1.0E-28 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Hamap MF_01396 ATP synthase subunit c [atpH]. 5 70 16.107 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Pfam PF00137 ATP synthase subunit C 6 68 2.1E-15 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 7 26 1.4E-20 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 45 70 1.4E-20 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 28 43 1.4E-20 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 ProSitePatterns PS00605 ATP synthase c subunit signature. 35 56 - T 14-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12630 cf1e8b5bebfc95161e321eb0aabaf5f3 72 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 16 70 8.9E-24 T 14-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 307 409 4.8E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 198 257 2.4E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 SUPERFAMILY SSF55874 255 413 1.14E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 Gene3D G3DSA:3.30.565.10 263 411 7.4E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 SMART SM00388 196 261 2.7E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 SMART SM00091 82 149 0.008 T 14-10-2018 IPR000014 PAS domain C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 Gene3D G3DSA:1.10.287.130 200 257 7.1E-13 T 14-10-2018 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 Gene3D G3DSA:3.30.450.20 76 183 4.0E-12 T 14-10-2018 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 409 9.1E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 9.1E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 9.1E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 9.1E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 80 181 8.6E-6 T 14-10-2018 IPR000014 PAS domain C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 SUPERFAMILY SSF47384 187 258 2.55E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 SMART SM00387 306 412 9.3E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 SUPERFAMILY SSF55785 78 182 1.05E-10 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_04115 55ea1a6221ef8ec6a12b993da553f854 423 Pfam PF13426 PAS domain 96 183 3.0E-6 T 14-10-2018 IPR000014 PAS domain C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 PIRSF PIRSF001456 1 385 1.5E-131 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 Gene3D G3DSA:3.60.150.10 1 390 2.5E-156 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 36.992 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 370 3.0E-131 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 SUPERFAMILY SSF103263 1 389 7.06E-152 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_24805 fcd0e2ab6d1ab332c870773571602c4f 390 Pfam PF01264 Chorismate synthase 1 364 6.6E-125 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I25_22210 632dc1a28681a0844c5107e446003689 539 SUPERFAMILY SSF51905 7 373 3.56E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_22210 632dc1a28681a0844c5107e446003689 539 Gene3D G3DSA:3.50.50.60 7 363 1.0E-106 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_22210 632dc1a28681a0844c5107e446003689 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 5.1E-41 T 14-10-2018 C2I25_22210 632dc1a28681a0844c5107e446003689 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 5.1E-41 T 14-10-2018 C2I25_22210 632dc1a28681a0844c5107e446003689 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 355 5.1E-41 T 14-10-2018 C2I25_22210 632dc1a28681a0844c5107e446003689 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 5.1E-41 T 14-10-2018 C2I25_22210 632dc1a28681a0844c5107e446003689 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 355 371 5.1E-41 T 14-10-2018 C2I25_22210 632dc1a28681a0844c5107e446003689 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 5.1E-41 T 14-10-2018 C2I25_22210 632dc1a28681a0844c5107e446003689 539 Pfam PF01494 FAD binding domain 5 367 8.5E-100 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 C2I25_22210 632dc1a28681a0844c5107e446003689 539 Gene3D G3DSA:3.40.30.120 396 537 5.9E-39 T 14-10-2018 C2I25_22210 632dc1a28681a0844c5107e446003689 539 Gene3D G3DSA:3.30.9.50 74 301 1.0E-106 T 14-10-2018 C2I25_01965 c523133388fc02824258d8cd8852bb7e 233 SUPERFAMILY SSF52540 3 229 1.36E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01965 c523133388fc02824258d8cd8852bb7e 233 Pfam PF00005 ABC transporter 19 161 6.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_01965 c523133388fc02824258d8cd8852bb7e 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_01965 c523133388fc02824258d8cd8852bb7e 233 Gene3D G3DSA:3.40.50.300 2 233 1.1E-55 T 14-10-2018 C2I25_01965 c523133388fc02824258d8cd8852bb7e 233 SMART SM00382 28 217 2.0E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_27545 456ea348d78a23466520dabcd3370c69 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 9.2E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_27545 456ea348d78a23466520dabcd3370c69 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 9.2E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_27545 456ea348d78a23466520dabcd3370c69 160 Pfam PF12802 MarR family 35 92 5.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_27545 456ea348d78a23466520dabcd3370c69 160 Gene3D G3DSA:1.10.10.10 1 144 2.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_27545 456ea348d78a23466520dabcd3370c69 160 SMART SM00347 29 129 1.2E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_27545 456ea348d78a23466520dabcd3370c69 160 SUPERFAMILY SSF46785 8 143 4.97E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_27545 456ea348d78a23466520dabcd3370c69 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I25_27180 d5e30633f17db1e29f5ef5c93b51bec4 186 Gene3D G3DSA:3.40.630.30 1 185 7.8E-47 T 14-10-2018 C2I25_27180 d5e30633f17db1e29f5ef5c93b51bec4 186 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 4.2E-29 T 14-10-2018 IPR000182 GNAT domain C2I25_27180 d5e30633f17db1e29f5ef5c93b51bec4 186 SUPERFAMILY SSF55729 8 179 5.04E-44 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_17185 064cb929d8987b8358931c556db63793 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 373 1.2E-184 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I25_17185 064cb929d8987b8358931c556db63793 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 373 1.3E-173 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I25_17185 064cb929d8987b8358931c556db63793 379 Gene3D G3DSA:3.20.20.105 1 373 2.9E-170 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I25_17185 064cb929d8987b8358931c556db63793 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.369 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I25_17185 064cb929d8987b8358931c556db63793 379 SUPERFAMILY SSF51713 2 369 3.4E-161 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I25_17185 064cb929d8987b8358931c556db63793 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 2.2E-92 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 Hamap MF_01694 Biotin synthase [bioB]. 21 328 40.537 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 SUPERFAMILY SSF102114 23 328 2.62E-74 T 14-10-2018 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 SMART SM00729 61 269 1.8E-35 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 SMART SM00876 237 327 3.6E-35 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 Pfam PF04055 Radical SAM superfamily 70 226 1.9E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 TIGRFAM TIGR00433 bioB: biotin synthase 33 326 2.9E-121 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 PIRSF PIRSF001619 4 332 3.7E-125 T 14-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 Gene3D G3DSA:3.20.20.70 22 330 8.8E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_18875 dbb25c3899aace53aaafac7afe84c5df 332 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 237 326 3.2E-14 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I25_26390 27f0aa439f96f2fcdeb6fcae0e8b2d86 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 8 31 2.9E-12 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_26390 27f0aa439f96f2fcdeb6fcae0e8b2d86 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 7 29 9.8E-11 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_11245 3e16335538871946d303093a8db559a5 290 Gene3D G3DSA:3.20.10.10 125 275 2.7E-45 T 14-10-2018 C2I25_11245 3e16335538871946d303093a8db559a5 290 Gene3D G3DSA:3.30.470.10 1 124 2.3E-37 T 14-10-2018 C2I25_11245 3e16335538871946d303093a8db559a5 290 Pfam PF01063 Amino-transferase class IV 29 250 6.5E-56 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 C2I25_11245 3e16335538871946d303093a8db559a5 290 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 C2I25_11245 3e16335538871946d303093a8db559a5 290 SUPERFAMILY SSF56752 1 272 1.23E-73 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 SUPERFAMILY SSF55874 396 526 2.36E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 Gene3D G3DSA:1.10.287.130 318 377 1.7E-5 T 14-10-2018 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 488 1.4E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 526 1.4E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 474 1.4E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 507 1.4E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 SMART SM00387 422 529 3.0E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 SUPERFAMILY SSF103190 40 171 1.96E-39 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 SUPERFAMILY SSF55785 215 314 6.75E-8 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 527 1.6E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 Pfam PF00989 PAS fold 216 315 4.4E-8 T 14-10-2018 IPR013767 PAS fold GO:0006355 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 SUPERFAMILY SSF55890 326 396 5.1E-14 T 14-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 329 374 3.8E-11 T 14-10-2018 IPR039506 SpoOB, alpha-helical domain C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 Pfam PF17203 Single cache domain 3 39 173 8.8E-23 T 14-10-2018 IPR033463 Single cache domain 3 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 Gene3D G3DSA:3.30.450.20 201 317 4.4E-23 T 14-10-2018 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 Gene3D G3DSA:3.30.450.20 33 174 1.2E-44 T 14-10-2018 C2I25_08605 8d7b1bace69ee20e1d1351746b5de2ad 534 Gene3D G3DSA:3.30.565.10 393 533 9.9E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_26685 5f1aa36b0433af09fb79e32d0a9326d4 151 PIRSF PIRSF006639 29 149 1.3E-44 T 14-10-2018 IPR011379 NTP Pyrophosphohydrolase MazG-related, GP37 C2I25_26685 5f1aa36b0433af09fb79e32d0a9326d4 151 SUPERFAMILY SSF101386 29 139 7.2E-20 T 14-10-2018 C2I25_26685 5f1aa36b0433af09fb79e32d0a9326d4 151 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 57 139 5.5E-13 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core C2I25_26685 5f1aa36b0433af09fb79e32d0a9326d4 151 Gene3D G3DSA:1.10.287.1080 12 136 2.2E-19 T 14-10-2018 C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 SUPERFAMILY SSF51395 448 1170 3.97E-161 T 14-10-2018 C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 Pfam PF01493 GXGXG motif 1230 1396 8.7E-20 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 Pfam PF01645 Conserved region in glutamate synthase 791 1151 5.1E-100 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 Pfam PF00310 Glutamine amidotransferases class-II 24 392 5.3E-48 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 SUPERFAMILY SSF69336 1213 1474 1.7E-43 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 Gene3D G3DSA:3.60.20.10 24 536 0.0 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 SUPERFAMILY SSF56235 24 398 3.38E-76 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 Gene3D G3DSA:2.160.20.60 1196 1478 2.2E-59 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 Pfam PF04898 Glutamate synthase central domain 449 729 5.5E-70 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 Gene3D G3DSA:3.20.20.70 474 1166 0.0 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_08950 ebf9846588f24986b66b5dc98a2fd8c8 1478 Gene3D G3DSA:3.20.20.70 423 776 0.0 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_24860 6a61c6322d328bf23e9986f8ff18b140 275 Pfam PF01522 Polysaccharide deacetylase 68 175 3.4E-27 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_24860 6a61c6322d328bf23e9986f8ff18b140 275 SUPERFAMILY SSF88713 65 264 1.68E-52 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_24860 6a61c6322d328bf23e9986f8ff18b140 275 Gene3D G3DSA:3.20.20.370 32 265 6.2E-63 T 14-10-2018 C2I25_03330 064801c53a429e94fab1b5d1cedd1c51 450 PIRSF PIRSF000521 28 450 2.6E-37 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_03330 064801c53a429e94fab1b5d1cedd1c51 450 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_03330 064801c53a429e94fab1b5d1cedd1c51 450 SUPERFAMILY SSF53383 20 448 2.23E-123 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_03330 064801c53a429e94fab1b5d1cedd1c51 450 Pfam PF00202 Aminotransferase class-III 31 446 1.0E-110 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_03330 064801c53a429e94fab1b5d1cedd1c51 450 Gene3D G3DSA:3.40.640.10 65 339 1.7E-152 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_03330 064801c53a429e94fab1b5d1cedd1c51 450 Gene3D G3DSA:3.90.1150.10 14 447 1.7E-152 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_15230 ed168f7c3e5990266ce77364348b0c40 253 SUPERFAMILY SSF46955 4 107 3.55E-29 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_15230 ed168f7c3e5990266ce77364348b0c40 253 Gene3D G3DSA:1.10.1660.10 2 113 4.0E-32 T 14-10-2018 C2I25_15230 ed168f7c3e5990266ce77364348b0c40 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 1.1E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15230 ed168f7c3e5990266ce77364348b0c40 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 1.1E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15230 ed168f7c3e5990266ce77364348b0c40 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 1.1E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15230 ed168f7c3e5990266ce77364348b0c40 253 SMART SM00422 4 73 1.0E-26 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15230 ed168f7c3e5990266ce77364348b0c40 253 Pfam PF13411 MerR HTH family regulatory protein 4 72 2.8E-22 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_15230 ed168f7c3e5990266ce77364348b0c40 253 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_06965 2584afd7da45e67fc0d0796ef1c5c251 518 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 503 7.8E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_06965 2584afd7da45e67fc0d0796ef1c5c251 518 SUPERFAMILY SSF56801 3 514 1.96E-145 T 14-10-2018 C2I25_06965 2584afd7da45e67fc0d0796ef1c5c251 518 Gene3D G3DSA:3.30.300.310 415 517 2.5E-33 T 14-10-2018 C2I25_06965 2584afd7da45e67fc0d0796ef1c5c251 518 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_06965 2584afd7da45e67fc0d0796ef1c5c251 518 Gene3D G3DSA:3.40.50.12780 8 414 6.6E-113 T 14-10-2018 C2I25_06965 2584afd7da45e67fc0d0796ef1c5c251 518 Pfam PF00501 AMP-binding enzyme 12 418 2.2E-99 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_13970 629e6ab6190bf3cc0f3f90e1c829bf02 297 Gene3D G3DSA:3.30.70.120 206 285 3.0E-19 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_13970 629e6ab6190bf3cc0f3f90e1c829bf02 297 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 238 292 8.4E-22 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_13970 629e6ab6190bf3cc0f3f90e1c829bf02 297 PIRSF PIRSF006483 13 297 1.3E-98 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_13970 629e6ab6190bf3cc0f3f90e1c829bf02 297 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 32 232 1.9E-59 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 Gene3D G3DSA:3.40.1110.10 347 466 1.1E-89 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 108 610 6.9E-85 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00941 Cadmium-transporting ATPase signature 65 77 5.8E-13 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00941 Cadmium-transporting ATPase signature 140 156 5.8E-13 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00941 Cadmium-transporting ATPase signature 220 234 5.8E-13 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00941 Cadmium-transporting ATPase signature 201 217 5.8E-13 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00941 Cadmium-transporting ATPase signature 120 140 5.8E-13 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 Pfam PF00122 E1-E2 ATPase 136 316 1.0E-50 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 85 636 2.7E-187 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 185 199 4.4E-29 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 470 4.4E-29 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 4.4E-29 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 4.4E-29 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 491 4.4E-29 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 4.4E-29 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 ProSitePatterns PS01229 Hypothetical cof family signature 2. 534 556 - T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 SUPERFAMILY SSF81665 87 617 4.58E-17 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 Gene3D G3DSA:3.40.50.1000 317 585 1.1E-89 T 14-10-2018 IPR023214 HAD superfamily C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 Gene3D G3DSA:2.70.150.20 129 240 1.0E-35 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 SUPERFAMILY SSF56784 335 633 9.16E-58 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 547 2.1E-41 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 85 388 2.5E-96 T 14-10-2018 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 SUPERFAMILY SSF81653 138 235 1.96E-24 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 338 344 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I25_09245 c99b9060b9606de11f7a100a975bacc7 641 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 97 636 2.6E-121 T 14-10-2018 C2I25_12320 05cc85e9ff8d0ff589d33e4088e972e0 290 Pfam PF00491 Arginase family 23 285 5.4E-80 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_12320 05cc85e9ff8d0ff589d33e4088e972e0 290 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 C2I25_12320 05cc85e9ff8d0ff589d33e4088e972e0 290 SUPERFAMILY SSF52768 12 289 2.52E-87 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily C2I25_12320 05cc85e9ff8d0ff589d33e4088e972e0 290 Gene3D G3DSA:3.40.800.10 16 289 1.2E-95 T 14-10-2018 C2I25_12320 05cc85e9ff8d0ff589d33e4088e972e0 290 TIGRFAM TIGR01230 agmatinase: agmatinase 10 286 2.2E-114 T 14-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 C2I25_12320 05cc85e9ff8d0ff589d33e4088e972e0 290 PIRSF PIRSF036979 1 290 5.8E-104 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_07405 8b52d81939e6be0960c520ae2a237a6b 551 Gene3D G3DSA:1.20.58.220 450 546 9.0E-23 T 14-10-2018 IPR038078 PhoU-like domain superfamily C2I25_07405 8b52d81939e6be0960c520ae2a237a6b 551 SUPERFAMILY SSF109755 336 539 1.26E-48 T 14-10-2018 C2I25_07405 8b52d81939e6be0960c520ae2a237a6b 551 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 9 316 1.4E-74 T 14-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 C2I25_07405 8b52d81939e6be0960c520ae2a237a6b 551 Gene3D G3DSA:1.20.58.220 338 446 4.1E-14 T 14-10-2018 IPR038078 PhoU-like domain superfamily C2I25_07405 8b52d81939e6be0960c520ae2a237a6b 551 Pfam PF02690 Na+/Pi-cotransporter 148 253 5.3E-19 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 C2I25_07405 8b52d81939e6be0960c520ae2a237a6b 551 Pfam PF02690 Na+/Pi-cotransporter 18 153 1.0E-50 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 C2I25_07405 8b52d81939e6be0960c520ae2a237a6b 551 Pfam PF01895 PhoU domain 453 536 4.7E-19 T 14-10-2018 IPR026022 PhoU domain C2I25_07405 8b52d81939e6be0960c520ae2a237a6b 551 Pfam PF01895 PhoU domain 348 434 2.9E-11 T 14-10-2018 IPR026022 PhoU domain C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PIRSF PIRSF006641 1 366 8.8E-167 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Gene3D G3DSA:3.40.50.300 4 281 7.6E-159 T 14-10-2018 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.5E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.5E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.5E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.5E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 SUPERFAMILY SSF52540 3 304 1.21E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.273 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 1.1E-160 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 8.7E-41 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Gene3D G3DSA:3.10.20.30 48 364 7.6E-159 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Pfam PF01926 50S ribosome-binding GTPase 5 123 9.7E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Gene3D G3DSA:1.10.150.300 113 200 7.6E-159 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 C2I25_11715 a94bd8ce1ea39c9ef8f297c797fbc11a 366 SUPERFAMILY SSF81271 282 363 6.1E-37 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 SUPERFAMILY SSF52540 64 291 5.59E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 SUPERFAMILY SSF50249 1 63 4.28E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Gene3D G3DSA:3.40.50.300 62 225 7.8E-47 T 14-10-2018 C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Pfam PF16745 RsgA N-terminal domain 3 56 1.0E-24 T 14-10-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Gene3D G3DSA:2.40.50.140 1 61 6.0E-26 T 14-10-2018 C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 283 3.1E-88 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 290 39.727 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Gene3D G3DSA:1.10.40.50 226 293 3.1E-24 T 14-10-2018 C2I25_20200 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Pfam PF03193 RsgA GTPase 59 225 1.3E-62 T 14-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 Gene3D G3DSA:3.30.9.10 102 343 2.3E-134 T 14-10-2018 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 Gene3D G3DSA:3.50.50.60 18 379 2.3E-134 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 SUPERFAMILY SSF54373 249 342 5.23E-11 T 14-10-2018 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 8.5E-31 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 336 342 8.5E-31 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 366 378 8.5E-31 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 8.5E-31 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 8.5E-31 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 8.5E-31 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 SUPERFAMILY SSF51905 16 237 6.8E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 Pfam PF01266 FAD dependent oxidoreductase 21 344 4.1E-51 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 531 3.2E-21 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 371 381 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_06265 42b22e8bba7fb4c17d5f49992644e81a 560 Gene3D G3DSA:1.10.8.870 421 551 9.9E-39 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_18440 f21b61d473885b9bf1550381169b447c 279 Gene3D G3DSA:3.10.290.10 2 64 3.4E-24 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_18440 f21b61d473885b9bf1550381169b447c 279 PIRSF PIRSF005578 1 269 6.3E-105 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 C2I25_18440 f21b61d473885b9bf1550381169b447c 279 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 1.7E-94 T 14-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 C2I25_18440 f21b61d473885b9bf1550381169b447c 279 Gene3D G3DSA:3.40.50.150 65 279 3.2E-85 T 14-10-2018 C2I25_18440 f21b61d473885b9bf1550381169b447c 279 SUPERFAMILY SSF55174 5 71 3.83E-13 T 14-10-2018 C2I25_18440 f21b61d473885b9bf1550381169b447c 279 SMART SM00363 6 71 1.1E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_18440 f21b61d473885b9bf1550381169b447c 279 Pfam PF01728 FtsJ-like methyltransferase 62 244 1.2E-18 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 C2I25_18440 f21b61d473885b9bf1550381169b447c 279 SUPERFAMILY SSF53335 54 246 4.48E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_18440 f21b61d473885b9bf1550381169b447c 279 Pfam PF01479 S4 domain 6 52 7.6E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_09265 2491fa965eacfa9cdebe2d9f9b228d4f 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 145 5.3E-42 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I25_09265 2491fa965eacfa9cdebe2d9f9b228d4f 154 Gene3D G3DSA:3.40.50.2300 1 154 6.7E-60 T 14-10-2018 C2I25_09265 2491fa965eacfa9cdebe2d9f9b228d4f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 5.4E-17 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I25_09265 2491fa965eacfa9cdebe2d9f9b228d4f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 5.4E-17 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I25_09265 2491fa965eacfa9cdebe2d9f9b228d4f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 5.4E-17 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I25_09265 2491fa965eacfa9cdebe2d9f9b228d4f 154 SMART SM00226 2 147 6.1E-52 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I25_09265 2491fa965eacfa9cdebe2d9f9b228d4f 154 SUPERFAMILY SSF52788 1 148 4.06E-47 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily C2I25_15100 465bfcda1d16c0fd98fb3d34d4dfde02 300 Gene3D G3DSA:3.40.50.10330 10 128 6.8E-101 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 C2I25_15100 465bfcda1d16c0fd98fb3d34d4dfde02 300 SUPERFAMILY SSF111331 6 297 4.84E-75 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily C2I25_15100 465bfcda1d16c0fd98fb3d34d4dfde02 300 SMART SM00046 8 134 4.7E-15 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 C2I25_15100 465bfcda1d16c0fd98fb3d34d4dfde02 300 Gene3D G3DSA:2.60.200.40 129 281 6.8E-101 T 14-10-2018 C2I25_15100 465bfcda1d16c0fd98fb3d34d4dfde02 300 Pfam PF00781 Diacylglycerol kinase catalytic domain 8 130 8.6E-35 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 C2I25_15100 465bfcda1d16c0fd98fb3d34d4dfde02 300 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 7 293 3.0E-80 T 14-10-2018 IPR005218 Diacylglycerol/lipid kinase C2I25_08055 55e9212cd51c281bcf4c283c9511fe4a 210 SUPERFAMILY SSF63817 12 206 1.57E-45 T 14-10-2018 IPR023365 Sortase domain superfamily C2I25_08055 55e9212cd51c281bcf4c283c9511fe4a 210 Gene3D G3DSA:2.40.260.10 53 210 1.8E-47 T 14-10-2018 IPR023365 Sortase domain superfamily C2I25_08055 55e9212cd51c281bcf4c283c9511fe4a 210 TIGRFAM TIGR01076 sortase_fam: sortase 81 205 4.0E-25 T 14-10-2018 IPR005754 Sortase family C2I25_08055 55e9212cd51c281bcf4c283c9511fe4a 210 Pfam PF04203 Sortase family 83 204 5.1E-29 T 14-10-2018 IPR005754 Sortase family C2I25_17660 2be63ee5b32b488799c4b05a2c7819ca 336 Gene3D G3DSA:3.40.50.300 1 140 1.3E-39 T 14-10-2018 C2I25_17660 2be63ee5b32b488799c4b05a2c7819ca 336 Gene3D G3DSA:1.20.272.10 211 335 5.8E-41 T 14-10-2018 C2I25_17660 2be63ee5b32b488799c4b05a2c7819ca 336 Gene3D G3DSA:1.10.8.60 141 210 5.4E-11 T 14-10-2018 C2I25_17660 2be63ee5b32b488799c4b05a2c7819ca 336 SUPERFAMILY SSF52540 10 210 5.84E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17660 2be63ee5b32b488799c4b05a2c7819ca 336 SUPERFAMILY SSF48019 214 333 1.67E-26 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 C2I25_17660 2be63ee5b32b488799c4b05a2c7819ca 336 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 14 333 3.3E-100 T 14-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 C2I25_17660 2be63ee5b32b488799c4b05a2c7819ca 336 Pfam PF06144 DNA polymerase III, delta subunit 17 191 3.9E-47 T 14-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 SUPERFAMILY SSF75553 484 687 3.14E-56 T 14-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 SMART SM00968 519 638 6.0E-40 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 638 1.6E-29 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 PIRSF PIRSF005719 1 1186 0.0 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 Gene3D G3DSA:3.30.70.1620 579 667 4.0E-67 T 14-10-2018 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 24.312 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1172 2.3E-64 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 Gene3D G3DSA:3.40.50.300 968 1188 1.4E-53 T 14-10-2018 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 Gene3D G3DSA:3.40.50.300 1 244 2.3E-59 T 14-10-2018 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 Gene3D G3DSA:1.20.1060.20 495 680 4.0E-67 T 14-10-2018 C2I25_20270 bf75d34124e5ea9766fbeefd78edf1ae 1189 SUPERFAMILY SSF52540 2 1174 7.36E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02910 670c586816cbafd70f03e78358cf36d3 436 SMART SM01027 252 363 3.2E-7 T 14-10-2018 IPR022712 Beta-Casp domain C2I25_02910 670c586816cbafd70f03e78358cf36d3 436 SMART SM00849 30 239 3.2E-10 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_02910 670c586816cbafd70f03e78358cf36d3 436 Gene3D G3DSA:3.40.50.10890 220 379 4.5E-84 T 14-10-2018 C2I25_02910 670c586816cbafd70f03e78358cf36d3 436 Gene3D G3DSA:3.60.15.10 24 407 4.5E-84 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_02910 670c586816cbafd70f03e78358cf36d3 436 Pfam PF00753 Metallo-beta-lactamase superfamily 27 197 6.3E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_02910 670c586816cbafd70f03e78358cf36d3 436 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 372 425 1.1E-6 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain C2I25_02910 670c586816cbafd70f03e78358cf36d3 436 SUPERFAMILY SSF56281 18 422 1.87E-69 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_02910 670c586816cbafd70f03e78358cf36d3 436 Pfam PF10996 Beta-Casp domain 227 362 5.6E-7 T 14-10-2018 IPR022712 Beta-Casp domain C2I25_21580 20434daa8bf27459fcd570c1ab3ce28c 343 SUPERFAMILY SSF51735 2 197 5.29E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_21580 20434daa8bf27459fcd570c1ab3ce28c 343 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 240 9.6E-17 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 C2I25_21580 20434daa8bf27459fcd570c1ab3ce28c 343 Gene3D G3DSA:3.30.360.10 122 335 2.6E-125 T 14-10-2018 C2I25_21580 20434daa8bf27459fcd570c1ab3ce28c 343 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 2.0E-22 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I25_21580 20434daa8bf27459fcd570c1ab3ce28c 343 Gene3D G3DSA:3.40.50.720 6 312 2.6E-125 T 14-10-2018 C2I25_21090 aff5d2302a5e0021793402e1e0295393 587 SMART SM00382 368 554 3.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_21090 aff5d2302a5e0021793402e1e0295393 587 Pfam PF00005 ABC transporter 359 508 3.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21090 aff5d2302a5e0021793402e1e0295393 587 Pfam PF00664 ABC transporter transmembrane region 24 297 2.2E-45 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_21090 aff5d2302a5e0021793402e1e0295393 587 Gene3D G3DSA:3.40.50.300 339 586 3.1E-90 T 14-10-2018 C2I25_21090 aff5d2302a5e0021793402e1e0295393 587 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_21090 aff5d2302a5e0021793402e1e0295393 587 SUPERFAMILY SSF90123 11 325 4.71E-79 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_21090 aff5d2302a5e0021793402e1e0295393 587 SUPERFAMILY SSF52540 335 578 1.74E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21090 aff5d2302a5e0021793402e1e0295393 587 Gene3D G3DSA:1.20.1560.10 1 326 1.8E-87 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 234 782 6.3E-176 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00941 Cadmium-transporting ATPase signature 349 365 6.1E-15 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00941 Cadmium-transporting ATPase signature 268 288 6.1E-15 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00941 Cadmium-transporting ATPase signature 368 382 6.1E-15 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00941 Cadmium-transporting ATPase signature 88 97 6.1E-15 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00941 Cadmium-transporting ATPase signature 99 120 6.1E-15 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Pfam PF00122 E1-E2 ATPase 284 464 1.3E-50 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 ProSitePatterns PS01047 Heavy-metal-associated domain. 12 41 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 SUPERFAMILY SSF56784 483 780 1.84E-60 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Gene3D G3DSA:3.40.50.1000 466 732 1.4E-82 T 14-10-2018 IPR023214 HAD superfamily C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 485 499 4.1E-21 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 333 347 4.1E-21 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 698 4.1E-21 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 703 715 4.1E-21 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 633 4.1E-21 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 SUPERFAMILY SSF55008 85 160 6.68E-12 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Pfam PF00403 Heavy-metal-associated domain 87 135 3.6E-10 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Pfam PF00403 Heavy-metal-associated domain 10 71 2.9E-10 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 SUPERFAMILY SSF81665 234 777 2.09E-13 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 234 784 4.1E-163 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Gene3D G3DSA:2.70.150.20 270 387 7.1E-32 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 487 493 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 ProSitePatterns PS01047 Heavy-metal-associated domain. 90 119 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Pfam PF00702 haloacid dehalogenase-like hydrolase 481 693 6.2E-35 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 SUPERFAMILY SSF55008 6 71 7.2E-12 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 SUPERFAMILY SSF81653 286 383 5.49E-25 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Gene3D G3DSA:3.30.70.100 87 172 5.4E-12 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Gene3D G3DSA:3.30.70.100 7 86 8.5E-11 T 14-10-2018 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 Gene3D G3DSA:3.40.1110.10 496 607 1.4E-82 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_08500 7c422d6953e0f955e911dac97791bced 788 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 257 759 1.7E-78 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_26125 e51ce4ec55817585f5f01aa0f6dec447 325 Pfam PF14528 LAGLIDADG-like domain 78 143 2.6E-5 T 14-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 C2I25_26125 e51ce4ec55817585f5f01aa0f6dec447 325 Pfam PF14528 LAGLIDADG-like domain 169 237 3.4E-6 T 14-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 C2I25_26125 e51ce4ec55817585f5f01aa0f6dec447 325 SUPERFAMILY SSF55608 161 252 5.48E-15 T 14-10-2018 IPR027434 Homing endonuclease C2I25_26125 e51ce4ec55817585f5f01aa0f6dec447 325 SUPERFAMILY SSF55608 76 145 2.76E-9 T 14-10-2018 IPR027434 Homing endonuclease C2I25_26125 e51ce4ec55817585f5f01aa0f6dec447 325 Gene3D G3DSA:3.10.28.10 74 235 2.5E-21 T 14-10-2018 IPR027434 Homing endonuclease C2I25_00320 2a19f6f8b7a0c5057a716513ac04eb2e 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 138 8.9E-24 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 C2I25_00320 2a19f6f8b7a0c5057a716513ac04eb2e 175 SUPERFAMILY SSF56784 2 173 6.8E-38 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_00320 2a19f6f8b7a0c5057a716513ac04eb2e 175 Pfam PF13242 HAD-hyrolase-like 91 167 1.4E-17 T 14-10-2018 C2I25_00320 2a19f6f8b7a0c5057a716513ac04eb2e 175 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 134 9.8E-28 T 14-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 C2I25_00320 2a19f6f8b7a0c5057a716513ac04eb2e 175 PIRSF PIRSF004682 1 172 3.3E-39 T 14-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 C2I25_00320 2a19f6f8b7a0c5057a716513ac04eb2e 175 Gene3D G3DSA:3.40.50.1000 4 175 3.9E-45 T 14-10-2018 IPR023214 HAD superfamily C2I25_13540 81faaeee3b65cc7d5d01c892312ece82 251 SUPERFAMILY SSF51351 1 249 1.57E-92 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13540 81faaeee3b65cc7d5d01c892312ece82 251 Gene3D G3DSA:3.20.20.70 2 250 2.2E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_13540 81faaeee3b65cc7d5d01c892312ece82 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.0E-60 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13540 81faaeee3b65cc7d5d01c892312ece82 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13540 81faaeee3b65cc7d5d01c892312ece82 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 59.456 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13540 81faaeee3b65cc7d5d01c892312ece82 251 Pfam PF00121 Triosephosphate isomerase 5 246 1.9E-91 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_04275 c12e43002a49c15437f37f9c628ee54f 258 Gene3D G3DSA:3.40.1010.10 1 117 4.0E-45 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I25_04275 c12e43002a49c15437f37f9c628ee54f 258 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 2.4E-52 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I25_04275 c12e43002a49c15437f37f9c628ee54f 258 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_04275 c12e43002a49c15437f37f9c628ee54f 258 SUPERFAMILY SSF53790 1 246 4.84E-84 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I25_04275 c12e43002a49c15437f37f9c628ee54f 258 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_04275 c12e43002a49c15437f37f9c628ee54f 258 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 2.0E-102 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_04275 c12e43002a49c15437f37f9c628ee54f 258 Gene3D G3DSA:3.30.950.10 118 257 4.1E-52 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 Gene3D G3DSA:2.40.50.140 1 66 1.8E-31 T 14-10-2018 C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 14-10-2018 IPR019844 Cold-shock conserved site C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 PIRSF PIRSF002599 1 66 6.7E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 SMART SM00357 3 66 3.7E-30 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.2E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 PRINTS PR00050 Cold shock protein signature 39 57 4.3E-19 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 PRINTS PR00050 Cold shock protein signature 4 19 4.3E-19 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 PRINTS PR00050 Cold shock protein signature 24 33 4.3E-19 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_14875 346f9ddffafaf6fabe18f9aac7cfc312 66 SUPERFAMILY SSF50249 1 64 6.38E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_16460 0a7fb20eb1dfa3eb01ead6a2d5f46b37 205 SUPERFAMILY SSF46689 9 76 1.1E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_16460 0a7fb20eb1dfa3eb01ead6a2d5f46b37 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 2.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16460 0a7fb20eb1dfa3eb01ead6a2d5f46b37 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.3E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16460 0a7fb20eb1dfa3eb01ead6a2d5f46b37 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.3E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16460 0a7fb20eb1dfa3eb01ead6a2d5f46b37 205 Gene3D G3DSA:1.10.357.10 6 197 4.8E-46 T 14-10-2018 C2I25_16460 0a7fb20eb1dfa3eb01ead6a2d5f46b37 205 Pfam PF14278 Transcriptional regulator C-terminal region 95 173 4.7E-14 T 14-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 PIRSF PIRSF036500 1 326 1.8E-200 T 14-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 310 1.1E-68 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 SMART SM01240 3 327 4.0E-119 T 14-10-2018 C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 4 324 3.7E-205 T 14-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 SUPERFAMILY SSF51412 4 314 1.57E-93 T 14-10-2018 C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 Gene3D G3DSA:3.20.20.70 1 327 2.8E-111 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 165 177 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 Hamap MF_01511 GMP reductase [guaC]. 2 325 64.85 T 14-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 C2I25_11835 94805437b5d9bcb3eabfbfcd5c3f3042 327 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 204 224 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 C2I25_24810 43b3494d68d84958ece64bc079e63def 366 Gene3D G3DSA:3.40.640.10 43 267 2.1E-106 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_24810 43b3494d68d84958ece64bc079e63def 366 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 353 57.334 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 C2I25_24810 43b3494d68d84958ece64bc079e63def 366 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 351 5.7E-102 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 C2I25_24810 43b3494d68d84958ece64bc079e63def 366 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 C2I25_24810 43b3494d68d84958ece64bc079e63def 366 Pfam PF00155 Aminotransferase class I and II 31 346 2.2E-50 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_24810 43b3494d68d84958ece64bc079e63def 366 Gene3D G3DSA:3.90.1150.10 8 344 2.1E-106 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_24810 43b3494d68d84958ece64bc079e63def 366 SUPERFAMILY SSF53383 4 349 3.2E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_06550 72daec5263a3e11e7bfef7aa7fc79fbc 332 Gene3D G3DSA:3.40.50.10440 12 186 7.9E-57 T 14-10-2018 C2I25_06550 72daec5263a3e11e7bfef7aa7fc79fbc 332 Pfam PF02733 Dak1 domain 18 328 3.1E-97 T 14-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_06550 72daec5263a3e11e7bfef7aa7fc79fbc 332 TIGRFAM TIGR02362 dhaK1b: probable dihydroxyacetone kinase DhaK1b subunit 3 332 1.2E-132 T 14-10-2018 IPR012735 Dihydroxyacetone kinase DhaK, subunit 1b C2I25_06550 72daec5263a3e11e7bfef7aa7fc79fbc 332 Gene3D G3DSA:3.30.1180.20 187 332 1.1E-42 T 14-10-2018 C2I25_06550 72daec5263a3e11e7bfef7aa7fc79fbc 332 SUPERFAMILY SSF82549 1 332 1.33E-103 T 14-10-2018 C2I25_20075 74f8fa4fb3b06bed8ffea23e0b15afe1 309 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 302 1.7E-127 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 C2I25_20075 74f8fa4fb3b06bed8ffea23e0b15afe1 309 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 239 259 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 C2I25_20075 74f8fa4fb3b06bed8ffea23e0b15afe1 309 SUPERFAMILY SSF51395 1 301 2.43E-88 T 14-10-2018 C2I25_20075 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 301 41.908 T 14-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 C2I25_20075 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Pfam PF01180 Dihydroorotate dehydrogenase 4 286 2.6E-96 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 C2I25_20075 74f8fa4fb3b06bed8ffea23e0b15afe1 309 PIRSF PIRSF000164 1 303 8.7E-86 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 C2I25_20075 74f8fa4fb3b06bed8ffea23e0b15afe1 309 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 C2I25_20075 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Gene3D G3DSA:3.20.20.70 1 303 1.1E-100 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 4 381 70.076 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 378 2.2E-152 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 Pfam PF00202 Aminotransferase class-III 14 378 1.6E-122 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 PIRSF PIRSF000521 155 381 1.2E-42 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 PIRSF PIRSF000521 4 115 2.0E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 PIRSF PIRSF000521 107 146 0.0085 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 205 242 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 Gene3D G3DSA:3.40.640.10 48 287 1.6E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 SUPERFAMILY SSF53383 4 378 1.67E-125 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_18775 a7cf8c81c3f1e34fe1b457f413fa517c 386 Gene3D G3DSA:3.90.1150.10 15 371 1.6E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_22310 c2d0989e79c5b99499a6e72cbdb630ce 321 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 C2I25_22310 c2d0989e79c5b99499a6e72cbdb630ce 321 SUPERFAMILY SSF51735 112 272 2.59E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22310 c2d0989e79c5b99499a6e72cbdb630ce 321 Gene3D G3DSA:3.40.50.720 123 265 9.5E-95 T 14-10-2018 C2I25_22310 c2d0989e79c5b99499a6e72cbdb630ce 321 SMART SM00829 10 319 6.9E-22 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_22310 c2d0989e79c5b99499a6e72cbdb630ce 321 SUPERFAMILY SSF50129 1 144 1.67E-35 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_22310 c2d0989e79c5b99499a6e72cbdb630ce 321 Pfam PF00107 Zinc-binding dehydrogenase 151 259 5.5E-27 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_22310 c2d0989e79c5b99499a6e72cbdb630ce 321 Gene3D G3DSA:3.90.180.10 9 318 9.5E-95 T 14-10-2018 C2I25_22310 c2d0989e79c5b99499a6e72cbdb630ce 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 4.1E-10 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_05870 1dbb53ff3a9dcf4b3e8b0542bea2df10 336 Pfam PF07968 Leukocidin/Hemolysin toxin family 65 329 8.6E-85 T 14-10-2018 IPR016183 Leukocidin/Hemolysin toxin GO:0005576|GO:0051715 C2I25_05870 1dbb53ff3a9dcf4b3e8b0542bea2df10 336 SUPERFAMILY SSF56959 32 335 9.32E-88 T 14-10-2018 IPR036435 Leukocidin/porin MspA superfamily C2I25_05870 1dbb53ff3a9dcf4b3e8b0542bea2df10 336 PRINTS PR01468 Staphylococcal bi-component toxin signature 68 87 3.4E-8 T 14-10-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 C2I25_05870 1dbb53ff3a9dcf4b3e8b0542bea2df10 336 PRINTS PR01468 Staphylococcal bi-component toxin signature 135 156 3.4E-8 T 14-10-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 C2I25_05870 1dbb53ff3a9dcf4b3e8b0542bea2df10 336 PRINTS PR01468 Staphylococcal bi-component toxin signature 261 278 3.4E-8 T 14-10-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 C2I25_05870 1dbb53ff3a9dcf4b3e8b0542bea2df10 336 TIGRFAM TIGR01002 hlyII: beta-channel forming cytolysin 11 332 8.1E-75 T 14-10-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 C2I25_05870 1dbb53ff3a9dcf4b3e8b0542bea2df10 336 Gene3D G3DSA:2.70.240.10 31 333 4.2E-95 T 14-10-2018 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 7 189 2.6E-63 T 14-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 PIRSF PIRSF000110 1 490 1.8E-190 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 3.6E-44 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 3.6E-44 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 3.6E-44 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 3.6E-44 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 3.6E-44 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 SUPERFAMILY SSF55347 179 490 8.5E-104 T 14-10-2018 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 487 2.9E-178 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 SUPERFAMILY SSF51735 2 185 1.97E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 486 6.4E-105 T 14-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 Gene3D G3DSA:3.40.50.720 2 177 5.4E-61 T 14-10-2018 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 3 488 80.577 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22910 e1c6f87b525e595bd74390d8ac5bb6ac 494 Gene3D G3DSA:3.30.360.10 178 489 6.4E-114 T 14-10-2018 C2I25_16035 2345438f446b6fcaeffbc651eaa9fe8f 314 SUPERFAMILY SSF103481 196 303 1.28E-6 T 14-10-2018 C2I25_16035 2345438f446b6fcaeffbc651eaa9fe8f 314 Pfam PF00892 EamA-like transporter family 162 298 1.9E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_16035 2345438f446b6fcaeffbc651eaa9fe8f 314 Pfam PF00892 EamA-like transporter family 8 145 8.1E-23 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_16035 2345438f446b6fcaeffbc651eaa9fe8f 314 SUPERFAMILY SSF103481 48 148 2.22E-5 T 14-10-2018 C2I25_02190 d5d3ac3021db6461193b81cbff3c3ba8 76 SUPERFAMILY SSF158221 1 40 6.02E-12 T 14-10-2018 C2I25_02190 d5d3ac3021db6461193b81cbff3c3ba8 76 Gene3D G3DSA:1.10.287.540 1 54 6.1E-16 T 14-10-2018 C2I25_02190 d5d3ac3021db6461193b81cbff3c3ba8 76 Pfam PF05979 Bacterial protein of unknown function (DUF896) 4 64 7.2E-24 T 14-10-2018 IPR009242 Protein of unknown function DUF896 C2I25_02190 d5d3ac3021db6461193b81cbff3c3ba8 76 Hamap MF_01103 UPF0291 protein . 1 58 13.56 T 14-10-2018 IPR009242 Protein of unknown function DUF896 C2I25_13860 1420340ae2572196ef7be188a5c828ea 232 Gene3D G3DSA:2.60.120.10 11 134 2.4E-79 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_13860 1420340ae2572196ef7be188a5c828ea 232 Gene3D G3DSA:2.60.120.10 9 229 2.4E-79 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_13860 1420340ae2572196ef7be188a5c828ea 232 SUPERFAMILY SSF51182 5 229 2.22E-68 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_13860 1420340ae2572196ef7be188a5c828ea 232 Pfam PF02678 Pirin 12 118 2.7E-33 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 C2I25_13860 1420340ae2572196ef7be188a5c828ea 232 PIRSF PIRSF006232 1 230 1.6E-58 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 3190 3223 2.3E-4 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2958 3022 3.61E-8 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.740 448 584 3.8E-8 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1838 1899 3.81E-7 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49401 447 582 7.33E-28 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1552 1616 1.88E-6 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1642 1704 4.32E-6 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2123 2181 1.69E-5 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2772 2836 3.26E-7 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1167 1228 4.32E-7 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2304 2366 1.92E-5 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2024 2088 1.14E-7 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2865 2927 7.45E-8 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2586 2650 3.92E-6 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49401 303 442 2.24E-29 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.1280 299 441 1.1E-22 T 14-10-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.1280 25 179 3.1E-15 T 14-10-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1358 1421 7.06E-6 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1928 1993 4.71E-7 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1451 1521 9.42E-6 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Pfam PF05737 Collagen binding domain 865 987 2.6E-19 T 14-10-2018 IPR008456 Collagen binding domain GO:0005518 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Pfam PF05737 Collagen binding domain 730 847 8.7E-5 T 14-10-2018 IPR008456 Collagen binding domain GO:0005518 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Pfam PF05737 Collagen binding domain 1012 1133 4.2E-13 T 14-10-2018 IPR008456 Collagen binding domain GO:0005518 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Pfam PF05737 Collagen binding domain 446 572 1.6E-20 T 14-10-2018 IPR008456 Collagen binding domain GO:0005518 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Pfam PF05737 Collagen binding domain 585 721 1.1E-10 T 14-10-2018 IPR008456 Collagen binding domain GO:0005518 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2683 2743 2.55E-6 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49401 34 176 7.12E-23 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2490 2556 1.49E-7 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49401 722 851 9.44E-18 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2210 2276 1.53E-7 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1264 1326 1.22E-6 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 3057 3119 1.14E-5 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49401 1006 1139 4.97E-26 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49401 864 990 4.06E-25 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 1738 1799 4.32E-6 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49478 2397 2458 2.08E-7 T 14-10-2018 C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1440 1534 5.9E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2292 2385 2.2E-26 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1915 2011 2.3E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2854 2947 4.2E-30 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2478 2571 2.3E-28 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2199 2291 2.5E-26 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2572 2666 1.7E-26 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2386 2477 1.1E-27 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1631 1726 1.5E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2105 2198 4.6E-26 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1155 1251 1.3E-15 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2667 2758 5.8E-26 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1727 1815 8.9E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2948 3040 3.5E-29 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1346 1439 2.1E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1535 1630 3.5E-26 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2759 2853 7.8E-29 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1252 1345 1.0E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 1819 1912 2.8E-27 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 3041 3141 6.2E-27 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 Gene3D G3DSA:2.60.40.10 2012 2104 1.5E-28 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_12380 4851539a14ba21a398ef87f554a4fbde 3224 SUPERFAMILY SSF49401 582 719 3.35E-23 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_20300 97b091df03da9b7fec46ac4a5306a916 171 Gene3D G3DSA:2.40.30.60 5 93 3.9E-21 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 C2I25_20300 97b091df03da9b7fec46ac4a5306a916 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 170 6.6E-54 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 C2I25_20300 97b091df03da9b7fec46ac4a5306a916 171 SUPERFAMILY SSF50346 100 170 2.43E-21 T 14-10-2018 IPR011033 PRC-barrel-like superfamily C2I25_20300 97b091df03da9b7fec46ac4a5306a916 171 SUPERFAMILY SSF50447 3 92 1.66E-21 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_20300 97b091df03da9b7fec46ac4a5306a916 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 170 24.865 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 C2I25_20300 97b091df03da9b7fec46ac4a5306a916 171 Gene3D G3DSA:2.30.30.240 95 171 1.0E-21 T 14-10-2018 C2I25_20300 97b091df03da9b7fec46ac4a5306a916 171 Pfam PF05239 PRC-barrel domain 97 170 1.1E-14 T 14-10-2018 IPR027275 PRC-barrel domain C2I25_20300 97b091df03da9b7fec46ac4a5306a916 171 Pfam PF01782 RimM N-terminal domain 7 91 3.8E-23 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Pfam PF05192 MutS domain III 261 551 6.4E-44 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Gene3D G3DSA:3.30.420.110 124 251 1.3E-11 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Gene3D G3DSA:3.40.50.300 560 870 1.4E-101 T 14-10-2018 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 SUPERFAMILY SSF52540 559 791 9.41E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 PIRSF PIRSF037677 158 837 6.0E-128 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 PIRSF PIRSF037677 1 179 8.5E-30 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 SUPERFAMILY SSF53150 114 270 1.03E-28 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Pfam PF00488 MutS domain V 604 790 4.3E-84 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Gene3D G3DSA:1.10.1420.10 256 551 6.1E-100 T 14-10-2018 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 SUPERFAMILY SSF55271 2 112 2.35E-42 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 879 25.537 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 SMART SM00533 274 583 7.0E-99 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 SMART SM00534 600 787 1.8E-117 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Pfam PF05190 MutS family domain IV 419 510 9.7E-27 T 14-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Pfam PF01624 MutS domain I 5 115 1.4E-46 T 14-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 807 0.0 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 SUPERFAMILY SSF48334 257 556 1.7E-86 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Pfam PF05188 MutS domain II 125 243 6.5E-7 T 14-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Gene3D G3DSA:1.10.1420.10 391 527 6.1E-100 T 14-10-2018 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 681 697 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_20670 91676878374a9ffbe6943ae1a4ed459d 890 Gene3D G3DSA:3.40.1170.10 1 117 3.1E-48 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1171 0.0 T 14-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1170 67.194 T 14-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 Gene3D G3DSA:3.40.50.300 1 133 1.8E-34 T 14-10-2018 C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 Gene3D G3DSA:3.40.50.300 135 278 4.8E-33 T 14-10-2018 C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 Pfam PF12705 PD-(D/E)XK nuclease superfamily 795 1139 2.6E-54 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 Gene3D G3DSA:3.40.50.300 282 422 1.5E-29 T 14-10-2018 C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 Gene3D G3DSA:3.40.50.300 558 701 2.4E-45 T 14-10-2018 C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 SUPERFAMILY SSF52540 309 754 5.42E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05715 e0b2752277b5013fd65db5d0e184545f 1171 Pfam PF13361 UvrD-like helicase C-terminal domain 300 670 6.6E-10 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 C2I25_04325 cc277edc432cfe68aed77ea423fc89bf 233 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 11 168 5.6E-40 T 14-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 C2I25_04325 cc277edc432cfe68aed77ea423fc89bf 233 Gene3D G3DSA:1.20.120.1760 3 170 1.5E-12 T 14-10-2018 C2I25_04325 cc277edc432cfe68aed77ea423fc89bf 233 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I25_04325 cc277edc432cfe68aed77ea423fc89bf 233 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 69 3.5E-13 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I25_13310 853568710c4d7892d839fb77b3c2a71b 228 Pfam PF00005 ABC transporter 20 165 1.4E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_13310 853568710c4d7892d839fb77b3c2a71b 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 1.6E-87 T 14-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 C2I25_13310 853568710c4d7892d839fb77b3c2a71b 228 SMART SM00382 27 221 1.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_13310 853568710c4d7892d839fb77b3c2a71b 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_13310 853568710c4d7892d839fb77b3c2a71b 228 Gene3D G3DSA:3.40.50.300 1 221 8.2E-66 T 14-10-2018 C2I25_13310 853568710c4d7892d839fb77b3c2a71b 228 SUPERFAMILY SSF52540 1 218 6.36E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25775 78f62b95dd246ef49f69fd0333fd4895 365 Gene3D G3DSA:2.120.10.30 9 359 3.2E-119 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I25_25775 78f62b95dd246ef49f69fd0333fd4895 365 SUPERFAMILY SSF63829 23 333 1.05E-21 T 14-10-2018 C2I25_25775 78f62b95dd246ef49f69fd0333fd4895 365 Pfam PF03022 Major royal jelly protein 80 340 8.4E-34 T 14-10-2018 IPR017996 Major royal jelly protein/protein yellow C2I25_23385 6e47fca12d35bd0c6c2076d5176348c3 411 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 77 323 4.3E-71 T 14-10-2018 IPR019079 Capsule synthesis protein, CapA C2I25_23385 6e47fca12d35bd0c6c2076d5176348c3 411 SMART SM00854 76 323 3.1E-86 T 14-10-2018 IPR019079 Capsule synthesis protein, CapA C2I25_23385 6e47fca12d35bd0c6c2076d5176348c3 411 SUPERFAMILY SSF56300 76 329 4.85E-42 T 14-10-2018 C2I25_23385 6e47fca12d35bd0c6c2076d5176348c3 411 Gene3D G3DSA:3.60.21.10 161 328 3.8E-6 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_02335 a8f8ab1db4be584dd20cb44e81836ce9 542 Gene3D G3DSA:3.40.190.10 49 529 4.8E-173 T 14-10-2018 C2I25_02335 a8f8ab1db4be584dd20cb44e81836ce9 542 SUPERFAMILY SSF53850 34 536 1.43E-127 T 14-10-2018 C2I25_02335 a8f8ab1db4be584dd20cb44e81836ce9 542 Gene3D G3DSA:3.10.105.10 290 512 4.8E-173 T 14-10-2018 C2I25_02335 a8f8ab1db4be584dd20cb44e81836ce9 542 PIRSF PIRSF002741 1 542 1.5E-109 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_02335 a8f8ab1db4be584dd20cb44e81836ce9 542 Gene3D G3DSA:3.90.76.10 68 190 4.8E-173 T 14-10-2018 C2I25_02335 a8f8ab1db4be584dd20cb44e81836ce9 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 460 7.3E-78 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_02710 6e936d29699c62a9198bb5f974891d64 228 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 225 2.5E-9 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I25_09615 546da03da4596a27234f056fde3057cc 335 SUPERFAMILY SSF81345 5 333 2.62E-78 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_09615 546da03da4596a27234f056fde3057cc 335 Gene3D G3DSA:1.10.3470.10 6 335 3.0E-90 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_09615 546da03da4596a27234f056fde3057cc 335 Pfam PF01032 FecCD transport family 20 333 1.4E-87 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_28395 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 289 1.1E-68 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I25_28395 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 SUPERFAMILY SSF161111 10 210 9.42E-54 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I25_28395 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 Gene3D G3DSA:3.30.70.1350 209 290 1.8E-17 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I25_28395 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 Pfam PF01545 Cation efflux family 17 208 2.3E-49 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I25_28395 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 Gene3D G3DSA:1.20.1510.10 12 208 2.5E-57 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I25_28395 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 Pfam PF16916 Dimerisation domain of Zinc Transporter 213 288 1.5E-19 T 14-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain C2I25_28395 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 SUPERFAMILY SSF160240 212 290 9.55E-22 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I25_10440 b60f9cd3f76dd327c9f7e21b4404fa2f 278 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 213 2.0E-65 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_10440 b60f9cd3f76dd327c9f7e21b4404fa2f 278 Gene3D G3DSA:3.30.70.120 189 265 2.0E-26 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_10440 b60f9cd3f76dd327c9f7e21b4404fa2f 278 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 218 272 2.8E-23 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_10440 b60f9cd3f76dd327c9f7e21b4404fa2f 278 PIRSF PIRSF006483 1 278 4.5E-89 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_06895 48abbd8c355a477323dc87863e59d7f0 317 Pfam PF01170 Putative RNA methylase family UPF0020 158 263 1.0E-6 T 14-10-2018 IPR000241 Putative RNA methylase domain C2I25_06895 48abbd8c355a477323dc87863e59d7f0 317 SUPERFAMILY SSF53335 72 296 3.77E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_06895 48abbd8c355a477323dc87863e59d7f0 317 Gene3D G3DSA:3.40.50.150 154 317 1.5E-20 T 14-10-2018 C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 SMART SM00490 323 401 0.62 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 SMART SM00490 488 573 5.0E-22 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 Gene3D G3DSA:3.40.50.300 441 613 6.3E-57 T 14-10-2018 C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 SUPERFAMILY SSF52540 376 585 7.1E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 SMART SM00487 253 442 3.3E-33 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 Pfam PF17191 RecG wedge domain 12 164 4.5E-14 T 14-10-2018 IPR033454 RecG, wedge domain C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 648 3.0E-245 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 SUPERFAMILY SSF50249 6 168 1.05E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 SUPERFAMILY SSF52540 173 436 5.33E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 Gene3D G3DSA:3.40.50.300 198 434 1.5E-86 T 14-10-2018 C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 Gene3D G3DSA:2.40.50.140 46 139 4.1E-9 T 14-10-2018 C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 Pfam PF00271 Helicase conserved C-terminal domain 455 572 5.0E-20 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_20235 c868cfd3641ac88e58db399864c6439f 682 Pfam PF00270 DEAD/DEAH box helicase 260 415 2.3E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_06790 71cad2055d94bba8e15dd50aa2070fbc 336 Pfam PF13020 Domain of unknown function (DUF3883) 217 309 7.9E-18 T 14-10-2018 IPR024975 Domain of unknown function DUF3883 C2I25_06790 71cad2055d94bba8e15dd50aa2070fbc 336 Pfam PF11907 Domain of unknown function (DUF3427) 3 144 3.4E-11 T 14-10-2018 IPR021835 Protein of unknown function DUF3427 C2I25_04320 eba01514e74b31882c1f69a7417f3bac 628 PIRSF PIRSF005091 1 616 5.1E-176 T 14-10-2018 IPR012160 Lipoteichoic acid synthase-like C2I25_04320 eba01514e74b31882c1f69a7417f3bac 628 Gene3D G3DSA:3.40.720.10 236 543 4.7E-77 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_04320 eba01514e74b31882c1f69a7417f3bac 628 SUPERFAMILY SSF53649 242 614 6.87E-72 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_04320 eba01514e74b31882c1f69a7417f3bac 628 Pfam PF00884 Sulfatase 244 533 5.5E-38 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 Pfam PF13089 Polyphosphate kinase N-terminal domain 17 122 4.7E-40 T 14-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 SUPERFAMILY SSF56024 332 512 5.97E-57 T 14-10-2018 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 Gene3D G3DSA:3.30.1840.10 10 325 1.3E-111 T 14-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 Hamap MF_00347 Polyphosphate kinase [ppk]. 14 697 29.422 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 16 693 3.4E-286 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 Gene3D G3DSA:3.30.870.10 333 515 7.8E-74 T 14-10-2018 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 Pfam PF02503 Polyphosphate kinase middle domain 132 337 1.8E-70 T 14-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 SUPERFAMILY SSF140356 14 117 4.45E-39 T 14-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 SUPERFAMILY SSF56024 516 698 4.71E-72 T 14-10-2018 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 Pfam PF13090 Polyphosphate kinase C-terminal domain 346 692 8.0E-156 T 14-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 SUPERFAMILY SSF143724 121 318 4.51E-61 T 14-10-2018 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 Gene3D G3DSA:3.30.870.10 516 702 1.6E-72 T 14-10-2018 C2I25_19515 eaa44cd8aee1c7de94213ef328defd87 702 PIRSF PIRSF015589 3 702 4.1E-280 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 C2I25_06040 2a441a75a29e8e49930a32401d18dd38 473 Gene3D G3DSA:1.10.3110.10 107 200 6.6E-147 T 14-10-2018 C2I25_06040 2a441a75a29e8e49930a32401d18dd38 473 Gene3D G3DSA:3.50.50.60 6 451 6.6E-147 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_06040 2a441a75a29e8e49930a32401d18dd38 473 SUPERFAMILY SSF51905 3 459 1.4E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_06040 2a441a75a29e8e49930a32401d18dd38 473 Pfam PF01593 Flavin containing amine oxidoreductase 12 459 3.8E-70 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I25_06040 2a441a75a29e8e49930a32401d18dd38 473 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 463 5.6E-129 T 14-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 C2I25_06040 2a441a75a29e8e49930a32401d18dd38 473 SUPERFAMILY SSF54373 301 409 8.34E-35 T 14-10-2018 C2I25_06040 2a441a75a29e8e49930a32401d18dd38 473 Gene3D G3DSA:3.90.660.20 41 408 6.6E-147 T 14-10-2018 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 458 1.2E-130 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 123 1.1E-39 T 14-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 Pfam PF01926 50S ribosome-binding GTPase 224 335 9.1E-26 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 Gene3D G3DSA:3.40.50.300 221 386 7.7E-108 T 14-10-2018 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 SUPERFAMILY SSF52540 77 375 1.33E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 SUPERFAMILY SSF116878 124 458 1.7E-51 T 14-10-2018 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 372 5.5E-28 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 Gene3D G3DSA:3.30.1360.120 1 123 6.9E-46 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 Gene3D G3DSA:1.20.120.430 124 458 7.7E-108 T 14-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 Pfam PF12631 MnmE helical domain 126 455 9.3E-61 T 14-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 C2I25_11670 bfbbca6ce30784d49b30a06327f039ce 458 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 458 34.228 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 C2I25_06940 a40729f0da5e463489f7833b8d8c0a6b 362 Pfam PF04230 Polysaccharide pyruvyl transferase 13 287 9.2E-52 T 14-10-2018 IPR007345 Polysaccharide pyruvyl transferase C2I25_06940 a40729f0da5e463489f7833b8d8c0a6b 362 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 2 305 1.5E-100 T 14-10-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB C2I25_06940 a40729f0da5e463489f7833b8d8c0a6b 362 SUPERFAMILY SSF53756 13 284 9.26E-14 T 14-10-2018 C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 SMART SM00861 355 526 4.8E-66 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 Pfam PF02780 Transketolase, C-terminal domain 549 658 8.9E-14 T 14-10-2018 IPR033248 Transketolase, C-terminal domain C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 665 8.4E-303 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 339 2.5E-158 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 SUPERFAMILY SSF52922 532 666 3.4E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 SUPERFAMILY SSF52518 4 326 6.63E-118 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 Gene3D G3DSA:3.40.50.970 4 331 7.7E-127 T 14-10-2018 C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 Gene3D G3DSA:3.40.50.970 332 539 1.1E-81 T 14-10-2018 C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 Pfam PF02779 Transketolase, pyrimidine binding domain 354 525 2.5E-43 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 SUPERFAMILY SSF52518 342 528 6.06E-69 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_21070 66dbe4514b6f00ee7a7b912ccc195f60 666 Gene3D G3DSA:3.40.50.920 541 666 1.3E-44 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_12860 b837ee1e546e2e01f92685602ced8ea8 473 Pfam PF01943 Polysaccharide biosynthesis protein 9 280 9.2E-7 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 SMART SM00421 160 209 0.0091 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 Pfam PF04542 Sigma-70 region 2 36 105 5.5E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 SUPERFAMILY SSF88659 123 210 1.57E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 PIRSF PIRSF002939 5 216 3.4E-111 T 14-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 Pfam PF08281 Sigma-70, region 4 162 205 1.1E-9 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 210 2.9E-117 T 14-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 SUPERFAMILY SSF88946 17 105 9.03E-22 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_11060 a6727c7cfbd4d74359595b6d82480aed 219 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 209 4.3E-27 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 SMART SM01390 3 91 6.9E-47 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 1.3E-29 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 14-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 Pfam PF01479 S4 domain 93 139 7.4E-20 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 SUPERFAMILY SSF55174 2 200 5.5E-68 T 14-10-2018 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 35.903 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 4.1E-84 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 Gene3D G3DSA:3.10.290.10 98 176 3.6E-31 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 Gene3D G3DSA:1.10.1050.10 1 97 1.6E-36 T 14-10-2018 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 SMART SM00363 92 156 8.6E-21 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_16010 52395cdfd9a9de6baa918f7a97730bcd 200 Gene3D G3DSA:1.10.1050.10 177 200 3.5E-5 T 14-10-2018 C2I25_18735 1e5806bea3fedf621c857d8fbd642188 292 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 288 3.6E-132 T 14-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 C2I25_18735 1e5806bea3fedf621c857d8fbd642188 292 Pfam PF03313 Serine dehydratase alpha chain 14 274 9.5E-72 T 14-10-2018 IPR005130 Serine dehydratase-like, alpha subunit C2I25_19800 194a3920c5ae9aa397d329ddc12f2829 332 SUPERFAMILY SSF56317 16 274 8.37E-59 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I25_19800 194a3920c5ae9aa397d329ddc12f2829 332 Hamap MF_01243 Formamidase [amiF]. 1 332 69.745 T 14-10-2018 IPR022843 Formamidase GO:0004328|GO:0006807 KEGG: 00460+3.5.1.49|KEGG: 00630+3.5.1.49|KEGG: 00910+3.5.1.49|MetaCyc: PWY-7142 C2I25_19800 194a3920c5ae9aa397d329ddc12f2829 332 Pfam PF00795 Carbon-nitrogen hydrolase 16 266 4.7E-36 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 C2I25_19800 194a3920c5ae9aa397d329ddc12f2829 332 Gene3D G3DSA:3.60.110.10 1 305 8.1E-119 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I25_21860 41eed5d92950be6c5dd63949163a9dbc 113 Pfam PF04266 ASCH domain 6 112 3.0E-16 T 14-10-2018 IPR007374 ASCH domain C2I25_21860 41eed5d92950be6c5dd63949163a9dbc 113 SUPERFAMILY SSF88697 1 112 3.64E-35 T 14-10-2018 IPR015947 PUA-like superfamily C2I25_21860 41eed5d92950be6c5dd63949163a9dbc 113 SMART SM01022 5 113 1.6E-16 T 14-10-2018 IPR007374 ASCH domain C2I25_21860 41eed5d92950be6c5dd63949163a9dbc 113 Gene3D G3DSA:2.30.130.30 1 113 5.8E-31 T 14-10-2018 C2I25_21860 41eed5d92950be6c5dd63949163a9dbc 113 PIRSF PIRSF016134 1 113 9.6E-44 T 14-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 C2I25_21545 11ec269a4c81a492cc502855aff626bc 150 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 14-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 C2I25_21545 11ec269a4c81a492cc502855aff626bc 150 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 2 149 5.6E-50 T 14-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 C2I25_21545 11ec269a4c81a492cc502855aff626bc 150 Gene3D G3DSA:3.20.20.70 1 150 5.9E-36 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_21545 11ec269a4c81a492cc502855aff626bc 150 Pfam PF13353 4Fe-4S single cluster domain 12 146 4.2E-37 T 14-10-2018 C2I25_21545 11ec269a4c81a492cc502855aff626bc 150 SUPERFAMILY SSF102114 22 101 7.59E-12 T 14-10-2018 C2I25_21545 11ec269a4c81a492cc502855aff626bc 150 Pfam PF04055 Radical SAM superfamily 20 108 4.4E-12 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_21545 11ec269a4c81a492cc502855aff626bc 150 PIRSF PIRSF000368 1 150 8.0E-55 T 14-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 C2I25_03220 f026b4a2f8d6849e711eb5a0133ed0e2 122 SMART SM00448 3 116 5.9E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_03220 f026b4a2f8d6849e711eb5a0133ed0e2 122 Gene3D G3DSA:3.40.50.12740 4 122 5.1E-37 T 14-10-2018 C2I25_03220 f026b4a2f8d6849e711eb5a0133ed0e2 122 Pfam PF00072 Response regulator receiver domain 5 116 8.8E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_03220 f026b4a2f8d6849e711eb5a0133ed0e2 122 SUPERFAMILY SSF52172 4 120 7.68E-36 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_04085 7a12acca1493d548e7fe4599846ebb5e 235 Gene3D G3DSA:3.40.50.1580 1 235 5.6E-80 T 14-10-2018 C2I25_04085 7a12acca1493d548e7fe4599846ebb5e 235 SUPERFAMILY SSF53167 2 233 1.83E-94 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I25_04085 7a12acca1493d548e7fe4599846ebb5e 235 Pfam PF01048 Phosphorylase superfamily 16 222 1.8E-43 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I25_04085 7a12acca1493d548e7fe4599846ebb5e 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 233 4.8E-109 T 14-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 C2I25_04085 7a12acca1493d548e7fe4599846ebb5e 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 14-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_04085 7a12acca1493d548e7fe4599846ebb5e 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 49.249 T 14-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 SMART SM00434 13 466 1.6E-294 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 706 2.0E-14 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 613 657 1.4E-9 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 711 757 4.7E-15 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 509 552 7.5E-13 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 761 805 1.8E-13 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 597 8.7E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 809 25.213 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Gene3D G3DSA:3.90.199.10 34 487 2.0E-219 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 SUPERFAMILY SSF101904 501 821 3.14E-116 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 34 473 2.7E-161 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Gene3D G3DSA:1.10.268.10 371 460 2.0E-219 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 808 0.0 T 14-10-2018 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Gene3D G3DSA:3.30.1360.40 238 334 2.0E-219 T 14-10-2018 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 SUPERFAMILY SSF56719 32 488 1.44E-183 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I25_11620 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Gene3D G3DSA:2.120.10.90 498 808 1.7E-133 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal C2I25_20240 a2bec94e433f86c76476ed25bcf4f57d 197 Gene3D G3DSA:3.10.129.10 70 189 2.8E-40 T 14-10-2018 C2I25_20240 a2bec94e433f86c76476ed25bcf4f57d 197 SUPERFAMILY SSF54637 76 185 4.16E-26 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_20240 a2bec94e433f86c76476ed25bcf4f57d 197 Gene3D G3DSA:1.10.10.10 1 62 1.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20240 a2bec94e433f86c76476ed25bcf4f57d 197 PIRSF PIRSF037733 1 193 1.1E-84 T 14-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 C2I25_20240 a2bec94e433f86c76476ed25bcf4f57d 197 Hamap MF_01814 Transcription factor FapR [fapR]. 3 190 41.082 T 14-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 C2I25_20240 a2bec94e433f86c76476ed25bcf4f57d 197 Pfam PF03061 Thioesterase superfamily 113 171 3.2E-6 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I25_20240 a2bec94e433f86c76476ed25bcf4f57d 197 SUPERFAMILY SSF46785 7 57 4.23E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 133 4.4E-13 T 14-10-2018 IPR011096 FTP domain C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 Gene3D G3DSA:3.10.170.10 247 403 8.1E-38 T 14-10-2018 C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 402 566 4.4E-51 T 14-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 Gene3D G3DSA:3.10.450.490 53 143 1.6E-5 T 14-10-2018 C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 390 406 2.4E-14 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 411 422 2.4E-14 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 481 497 2.4E-14 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 Pfam PF03413 Peptidase propeptide and YPEB domain 150 219 2.0E-5 T 14-10-2018 IPR025711 PepSY domain C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 248 399 3.1E-34 T 14-10-2018 IPR013856 Peptidase M4 domain GO:0004222 C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 SUPERFAMILY SSF55486 246 566 3.48E-68 T 14-10-2018 C2I25_25920 ba8ca1cbf11bd1e47e020aa71e8a44b6 567 Gene3D G3DSA:1.10.390.10 404 566 3.8E-48 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily C2I25_25885 391d64996243a7d5238c9415bb738b46 308 Pfam PF13602 Zinc-binding dehydrogenase 187 305 3.7E-25 T 14-10-2018 C2I25_25885 391d64996243a7d5238c9415bb738b46 308 Gene3D G3DSA:3.40.50.720 125 274 4.1E-96 T 14-10-2018 C2I25_25885 391d64996243a7d5238c9415bb738b46 308 SUPERFAMILY SSF51735 117 239 5.11E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_25885 391d64996243a7d5238c9415bb738b46 308 SMART SM00829 10 305 9.7E-30 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_25885 391d64996243a7d5238c9415bb738b46 308 Gene3D G3DSA:3.90.180.10 8 305 4.1E-96 T 14-10-2018 C2I25_25885 391d64996243a7d5238c9415bb738b46 308 SUPERFAMILY SSF50129 1 144 3.2E-36 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_25885 391d64996243a7d5238c9415bb738b46 308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 6.1E-11 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 SUPERFAMILY SSF102114 7 306 7.46E-79 T 14-10-2018 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 337 40.886 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 Pfam PF04055 Radical SAM superfamily 19 183 1.1E-30 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 Gene3D G3DSA:3.20.20.70 1 337 1.6E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 Pfam PF13353 4Fe-4S single cluster domain 21 128 1.6E-7 T 14-10-2018 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 SMART SM00729 14 225 4.9E-15 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 Pfam PF06463 Molybdenum Cofactor Synthesis C 189 316 2.4E-36 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_01030 b18adfad0c08b2b1ac37e28f71f49f80 337 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 337 6.4E-120 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 Pfam PF00067 Cytochrome P450 3 373 3.8E-38 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 SUPERFAMILY SSF48264 22 391 6.02E-86 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 PRINTS PR00359 B-class P450 signature 88 99 9.0E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 PRINTS PR00359 B-class P450 signature 320 335 9.0E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 PRINTS PR00359 B-class P450 signature 134 150 9.0E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 PRINTS PR00359 B-class P450 signature 194 216 9.0E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 PRINTS PR00359 B-class P450 signature 342 351 9.0E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 PRINTS PR00359 B-class P450 signature 351 362 9.0E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 PRINTS PR00359 B-class P450 signature 292 319 9.0E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 PRINTS PR00359 B-class P450 signature 151 166 9.0E-42 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 C2I25_26445 386573a5ed37093bb76994b28aba2bf5 404 Gene3D G3DSA:1.10.630.10 4 404 5.1E-110 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 SUPERFAMILY SSF81464 14 116 5.72E-21 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 Pfam PF00034 Cytochrome c 254 346 1.9E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 150 227 1.8E-15 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 48 107 3.7E-10 T 14-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 Gene3D G3DSA:1.10.287.90 27 113 1.8E-25 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 Gene3D G3DSA:2.60.40.2600 126 349 7.3E-69 T 14-10-2018 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 SUPERFAMILY SSF49503 124 289 4.52E-43 T 14-10-2018 IPR008972 Cupredoxin C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 SUPERFAMILY SSF46626 249 346 1.07E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 210 227 1.2E-14 T 14-10-2018 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 192 209 1.2E-14 T 14-10-2018 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 96 116 1.2E-14 T 14-10-2018 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 172 192 1.2E-14 T 14-10-2018 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 84 96 1.2E-14 T 14-10-2018 C2I25_19775 299ec4f23fc2823c2169d2a4b93aa948 349 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 31 237 5.1E-55 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 Gene3D G3DSA:2.130.10.30 212 291 2.3E-19 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 Gene3D G3DSA:2.130.10.30 16 211 2.0E-36 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 217 227 - T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 252 281 1.1E-5 T 14-10-2018 C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 214 243 1.6E-7 T 14-10-2018 C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 100 128 2.9E-5 T 14-10-2018 C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 138 167 1.7E-5 T 14-10-2018 C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 18 43 1.8E-5 T 14-10-2018 C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 SUPERFAMILY SSF50985 68 293 3.47E-44 T 14-10-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II C2I25_02450 d154eb2756a65b125725a61f9bcd5018 295 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 18 28 - T 14-10-2018 IPR000408 Regulator of chromosome condensation, RCC1 C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 Gene3D G3DSA:1.10.10.10 1 90 1.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 SUPERFAMILY SSF53850 91 246 1.02E-8 T 14-10-2018 C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.6E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 Gene3D G3DSA:3.40.190.10 114 153 2.5E-5 T 14-10-2018 C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 Gene3D G3DSA:3.40.190.10 154 226 2.5E-5 T 14-10-2018 C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_01950 0b0bba45933bdcdb8288ad7af7ebeaaa 262 SUPERFAMILY SSF46785 2 106 2.2E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_03695 7775ee716505df849375f890a7b75a4a 278 SUPERFAMILY SSF51621 3 263 5.1E-109 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I25_03695 7775ee716505df849375f890a7b75a4a 278 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 43.469 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 C2I25_03695 7775ee716505df849375f890a7b75a4a 278 Gene3D G3DSA:3.20.20.60 2 273 1.2E-118 T 14-10-2018 C2I25_03695 7775ee716505df849375f890a7b75a4a 278 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 263 2.1E-119 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 C2I25_03695 7775ee716505df849375f890a7b75a4a 278 PIRSF PIRSF000388 1 266 2.2E-110 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 C2I25_03695 7775ee716505df849375f890a7b75a4a 278 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 259 8.6E-114 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 C2I25_07360 c7e22b3f634a1ff51c6e7d6466a69bc5 361 Gene3D G3DSA:2.40.100.10 243 361 5.9E-43 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_07360 c7e22b3f634a1ff51c6e7d6466a69bc5 361 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 358 1.9E-139 T 14-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic C2I25_07360 c7e22b3f634a1ff51c6e7d6466a69bc5 361 Gene3D G3DSA:3.20.20.70 1 242 6.6E-98 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_07360 c7e22b3f634a1ff51c6e7d6466a69bc5 361 SUPERFAMILY SSF51445 2 243 4.02E-92 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_07360 c7e22b3f634a1ff51c6e7d6466a69bc5 361 SUPERFAMILY SSF50891 246 360 1.44E-34 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_13140 ffdcf5b898a1bbcf84b9a4f609cd46e9 126 Gene3D G3DSA:3.10.180.10 1 125 6.6E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_13140 ffdcf5b898a1bbcf84b9a4f609cd46e9 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 117 1.9E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_13140 ffdcf5b898a1bbcf84b9a4f609cd46e9 126 SUPERFAMILY SSF54593 1 125 3.66E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_28575 e168965579d00cef08bbd1d7cc40c54f 475 PIRSF PIRSF006060 4 469 3.6E-59 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_28575 e168965579d00cef08bbd1d7cc40c54f 475 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 9 474 3.6E-171 T 14-10-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 C2I25_28575 e168965579d00cef08bbd1d7cc40c54f 475 Pfam PF13520 Amino acid permease 12 414 2.7E-68 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_28575 e168965579d00cef08bbd1d7cc40c54f 475 Gene3D G3DSA:1.20.1740.10 7 461 9.5E-66 T 14-10-2018 C2I25_21535 adca56b29d97e8128613f7a61514cb69 198 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 192 20.22 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I25_21535 adca56b29d97e8128613f7a61514cb69 198 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 183 4.7E-52 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I25_21535 adca56b29d97e8128613f7a61514cb69 198 SMART SM01207 9 184 3.7E-82 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I25_21535 adca56b29d97e8128613f7a61514cb69 198 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 6 191 4.6E-63 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 Gene3D G3DSA:3.30.70.270 266 439 1.9E-43 T 14-10-2018 C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 260 6.9E-18 T 14-10-2018 IPR000014 PAS domain C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 SUPERFAMILY SSF55785 152 260 1.52E-17 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 SUPERFAMILY SSF55785 24 133 3.84E-9 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 Gene3D G3DSA:3.20.20.450 440 689 7.8E-94 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 SMART SM00267 259 427 1.1E-38 T 14-10-2018 IPR000160 GGDEF domain C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 SMART SM00052 437 682 1.7E-112 T 14-10-2018 IPR001633 EAL domain C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 Pfam PF00563 EAL domain 443 677 2.5E-71 T 14-10-2018 IPR001633 EAL domain C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 Pfam PF08448 PAS fold 25 135 7.7E-26 T 14-10-2018 IPR013656 PAS fold-4 C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 Pfam PF08448 PAS fold 157 260 1.7E-10 T 14-10-2018 IPR013656 PAS fold-4 C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 Pfam PF00990 Diguanylate cyclase, GGDEF domain 271 422 2.9E-36 T 14-10-2018 IPR000160 GGDEF domain C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 Gene3D G3DSA:3.30.450.20 146 261 4.4E-17 T 14-10-2018 C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 Gene3D G3DSA:3.30.450.20 21 145 2.1E-14 T 14-10-2018 C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 SUPERFAMILY SSF141868 442 688 9.29E-85 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 SMART SM00091 19 88 16.0 T 14-10-2018 IPR000014 PAS domain C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 SMART SM00091 147 213 1.6E-8 T 14-10-2018 IPR000014 PAS domain C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 424 3.2E-27 T 14-10-2018 IPR000160 GGDEF domain C2I25_08760 b9aeaaf5c82c18d126e50d1f67b2729f 689 SUPERFAMILY SSF55073 276 427 2.04E-36 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_27840 20fccde627724609856ff0641ca3855e 598 Pfam PF00664 ABC transporter transmembrane region 43 314 3.4E-56 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_27840 20fccde627724609856ff0641ca3855e 598 Gene3D G3DSA:1.20.1560.10 9 346 9.0E-102 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_27840 20fccde627724609856ff0641ca3855e 598 Pfam PF00005 ABC transporter 376 525 4.5E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_27840 20fccde627724609856ff0641ca3855e 598 Gene3D G3DSA:3.40.50.300 356 598 1.8E-87 T 14-10-2018 C2I25_27840 20fccde627724609856ff0641ca3855e 598 SMART SM00382 385 571 4.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_27840 20fccde627724609856ff0641ca3855e 598 SUPERFAMILY SSF52540 349 596 8.91E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_27840 20fccde627724609856ff0641ca3855e 598 SUPERFAMILY SSF90123 31 343 9.68E-82 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_27840 20fccde627724609856ff0641ca3855e 598 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_01685 d17b41d2bd7575016d0f740b14d4c123 68 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_01685 d17b41d2bd7575016d0f740b14d4c123 68 Gene3D G3DSA:1.10.8.910 8 68 4.1E-30 T 14-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I25_01685 d17b41d2bd7575016d0f740b14d4c123 68 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 9 62 1.6E-21 T 14-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I25_01685 d17b41d2bd7575016d0f740b14d4c123 68 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_23060 f47b82932f5a91362e41a4bd86d52673 153 SUPERFAMILY SSF55729 30 138 9.45E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_23060 f47b82932f5a91362e41a4bd86d52673 153 Gene3D G3DSA:3.40.630.30 2 135 5.9E-18 T 14-10-2018 C2I25_23060 f47b82932f5a91362e41a4bd86d52673 153 Pfam PF13673 Acetyltransferase (GNAT) domain 50 148 3.7E-14 T 14-10-2018 IPR000182 GNAT domain C2I25_21695 ac5933fdfd1cd01a4fa3055fbe35ebfc 365 Gene3D G3DSA:1.20.1740.10 3 365 3.6E-7 T 14-10-2018 C2I25_21695 ac5933fdfd1cd01a4fa3055fbe35ebfc 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 362 1.1E-106 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_21695 ac5933fdfd1cd01a4fa3055fbe35ebfc 365 Pfam PF03845 Spore germination protein 9 321 6.0E-59 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 9.5E-16 T 14-10-2018 C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.5E-16 T 14-10-2018 C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 308 330 9.5E-16 T 14-10-2018 C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 9.5E-16 T 14-10-2018 C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 Gene3D G3DSA:3.50.50.60 285 342 2.3E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 Gene3D G3DSA:3.50.50.60 3 111 6.8E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 Gene3D G3DSA:3.50.50.60 112 169 6.8E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 Gene3D G3DSA:3.50.50.60 233 284 2.3E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.5E-9 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 318 336 1.5E-9 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 SUPERFAMILY SSF51905 1 354 1.03E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25385 82196e9d57cfb35b381fdd1cbe074ecb 415 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 342 1.0E-16 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_01485 804af63e8490884bed5a601ec43157b6 345 Hamap MF_01614 NADPH dehydrogenase [namA]. 2 338 67.404 T 14-10-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 C2I25_01485 804af63e8490884bed5a601ec43157b6 345 Gene3D G3DSA:3.20.20.70 1 339 2.2E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_01485 804af63e8490884bed5a601ec43157b6 345 SUPERFAMILY SSF51395 3 333 1.72E-113 T 14-10-2018 C2I25_01485 804af63e8490884bed5a601ec43157b6 345 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 320 6.1E-90 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 C2I25_13015 e18b6d186159dd93bb766e39e4d40948 433 SUPERFAMILY SSF53448 64 340 8.44E-54 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_13015 e18b6d186159dd93bb766e39e4d40948 433 Pfam PF13641 Glycosyltransferase like family 2 69 294 1.3E-33 T 14-10-2018 C2I25_13015 e18b6d186159dd93bb766e39e4d40948 433 Gene3D G3DSA:3.90.550.10 58 280 3.0E-45 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_25230 e13b8e013baef898d026af8026ee4f89 286 Gene3D G3DSA:3.40.50.10170 1 153 8.4E-44 T 14-10-2018 C2I25_25230 e13b8e013baef898d026af8026ee4f89 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 283 2.3E-82 T 14-10-2018 IPR003797 DegV C2I25_25230 e13b8e013baef898d026af8026ee4f89 286 SUPERFAMILY SSF82549 1 284 1.23E-88 T 14-10-2018 C2I25_25230 e13b8e013baef898d026af8026ee4f89 286 Gene3D G3DSA:3.30.1180.10 157 285 3.0E-48 T 14-10-2018 C2I25_25230 e13b8e013baef898d026af8026ee4f89 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 281 3.5E-95 T 14-10-2018 IPR003797 DegV C2I25_27365 396795f86fcb7611040e2313b9be766d 314 SUPERFAMILY SSF52172 5 135 1.71E-24 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_27365 396795f86fcb7611040e2313b9be766d 314 Gene3D G3DSA:3.40.50.12740 3 164 3.0E-23 T 14-10-2018 C2I25_27365 396795f86fcb7611040e2313b9be766d 314 Pfam PF08664 YcbB domain 166 302 1.3E-49 T 14-10-2018 IPR013972 YcbB domain C2I25_27365 396795f86fcb7611040e2313b9be766d 314 Pfam PF00072 Response regulator receiver domain 4 114 6.1E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_27365 396795f86fcb7611040e2313b9be766d 314 SMART SM00448 1 114 3.3E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_20900 1c851ef0d03889f9d47da9c143aa0206 360 ProSitePatterns PS01095 Chitinases family 18 active site. 137 145 - T 14-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 C2I25_20900 1c851ef0d03889f9d47da9c143aa0206 360 Pfam PF00704 Glycosyl hydrolases family 18 36 338 2.2E-29 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 C2I25_20900 1c851ef0d03889f9d47da9c143aa0206 360 Gene3D G3DSA:3.20.20.80 28 360 1.9E-110 T 14-10-2018 C2I25_20900 1c851ef0d03889f9d47da9c143aa0206 360 SMART SM00636 34 338 1.3E-7 T 14-10-2018 IPR011583 Chitinase II GO:0008061 C2I25_20900 1c851ef0d03889f9d47da9c143aa0206 360 SUPERFAMILY SSF51445 33 347 1.13E-59 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_00405 0a58174e96f18fca3945e01fec057d2f 461 SUPERFAMILY SSF140453 2 92 9.55E-17 T 14-10-2018 IPR036689 ESAT-6-like superfamily C2I25_00405 0a58174e96f18fca3945e01fec057d2f 461 Pfam PF14449 Pre-toxin TG 108 174 3.6E-18 T 14-10-2018 IPR027797 Pre-toxin TG domain C2I25_00405 0a58174e96f18fca3945e01fec057d2f 461 Gene3D G3DSA:1.10.287.850 1 96 1.0E-26 T 14-10-2018 C2I25_00405 0a58174e96f18fca3945e01fec057d2f 461 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 2 90 6.6E-22 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_00405 0a58174e96f18fca3945e01fec057d2f 461 Pfam PF06013 Proteins of 100 residues with WXG 3 87 1.3E-18 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 2.3E-136 T 14-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 Gene3D G3DSA:3.90.110.10 148 313 5.3E-65 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 Gene3D G3DSA:3.40.50.720 2 147 1.2E-59 T 14-10-2018 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 SUPERFAMILY SSF56327 146 312 1.21E-59 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 SUPERFAMILY SSF51735 4 145 2.14E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 311 5.3E-39 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 14-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 9.3E-50 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 9.3E-50 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 9.3E-50 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 9.3E-50 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 9.3E-50 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 314 48.631 T 14-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 3.8E-49 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_14805 2a586501bda77ff906a35aecfcc1d86c 314 PIRSF PIRSF000102 2 313 1.3E-117 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_08450 b2f84b686006fbb25d8bfea7dc832013 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 125 5.8E-18 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_08450 b2f84b686006fbb25d8bfea7dc832013 128 SUPERFAMILY SSF54593 1 127 1.18E-30 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_08450 b2f84b686006fbb25d8bfea7dc832013 128 Gene3D G3DSA:3.10.180.10 8 127 4.9E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_03845 9c35b383b0f59639f9e4d665d89b4ca5 189 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 5.5E-77 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I25_03845 9c35b383b0f59639f9e4d665d89b4ca5 189 SUPERFAMILY SSF55620 3 187 2.08E-77 T 14-10-2018 C2I25_03845 9c35b383b0f59639f9e4d665d89b4ca5 189 Gene3D G3DSA:1.10.286.10 1 54 1.5E-22 T 14-10-2018 C2I25_03845 9c35b383b0f59639f9e4d665d89b4ca5 189 Gene3D G3DSA:3.30.1130.10 55 189 2.3E-60 T 14-10-2018 C2I25_03845 9c35b383b0f59639f9e4d665d89b4ca5 189 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 41.873 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I25_03845 9c35b383b0f59639f9e4d665d89b4ca5 189 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I25_03845 9c35b383b0f59639f9e4d665d89b4ca5 189 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I25_03845 9c35b383b0f59639f9e4d665d89b4ca5 189 Pfam PF01227 GTP cyclohydrolase I 9 186 1.4E-79 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I25_05210 3291ff816b1b5ae7ab914914ec35a930 253 SUPERFAMILY SSF51366 3 248 1.41E-74 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I25_05210 3291ff816b1b5ae7ab914914ec35a930 253 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 44 62 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 C2I25_05210 3291ff816b1b5ae7ab914914ec35a930 253 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 251 32.758 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 C2I25_05210 3291ff816b1b5ae7ab914914ec35a930 253 Gene3D G3DSA:3.20.20.70 1 251 5.1E-92 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_05210 3291ff816b1b5ae7ab914914ec35a930 253 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 245 5.3E-82 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 C2I25_02095 97ae172c202b4c9b610fa8534a8c6495 279 SUPERFAMILY SSF55909 5 279 1.2E-65 T 14-10-2018 C2I25_02095 97ae172c202b4c9b610fa8534a8c6495 279 Pfam PF02274 Amidinotransferase 77 278 6.2E-43 T 14-10-2018 C2I25_02095 97ae172c202b4c9b610fa8534a8c6495 279 Gene3D G3DSA:3.75.10.10 3 279 7.7E-72 T 14-10-2018 C2I25_13270 ed14e260dcfc30470c1966b2399eeb93 449 SMART SM00490 329 410 3.8E-11 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_13270 ed14e260dcfc30470c1966b2399eeb93 449 SMART SM00487 103 285 2.4E-13 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_13270 ed14e260dcfc30470c1966b2399eeb93 449 Gene3D G3DSA:3.40.50.300 292 426 3.4E-20 T 14-10-2018 C2I25_13270 ed14e260dcfc30470c1966b2399eeb93 449 Pfam PF04851 Type III restriction enzyme, res subunit 108 254 1.2E-7 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 C2I25_13270 ed14e260dcfc30470c1966b2399eeb93 449 SUPERFAMILY SSF52540 118 422 1.05E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13270 ed14e260dcfc30470c1966b2399eeb93 449 Pfam PF00271 Helicase conserved C-terminal domain 312 408 2.7E-9 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_13270 ed14e260dcfc30470c1966b2399eeb93 449 Gene3D G3DSA:3.40.50.300 106 270 3.1E-20 T 14-10-2018 C2I25_13025 e8447abbde085040b1350695e4732958 403 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 196 401 2.5E-71 T 14-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I25_13025 e8447abbde085040b1350695e4732958 403 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 401 2.5E-138 T 14-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 C2I25_13025 e8447abbde085040b1350695e4732958 403 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 9 81 4.2E-22 T 14-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 390 421 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 23 451 2.9E-176 T 14-10-2018 C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 Pfam PF01938 TRAM domain 10 65 1.2E-12 T 14-10-2018 IPR002792 TRAM domain C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 SUPERFAMILY SSF53335 75 458 1.21E-82 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 95 458 2.5E-18 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 SUPERFAMILY SSF50249 3 66 4.85E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 Gene3D G3DSA:2.40.50.140 2 86 4.0E-24 T 14-10-2018 C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 Gene3D G3DSA:3.40.1350.30 136 291 3.3E-117 T 14-10-2018 C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 441 451 - T 14-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site C2I25_09165 47fcf45412a6708478697bf48ab15d10 459 Gene3D G3DSA:3.40.50.150 88 453 3.3E-117 T 14-10-2018 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 SMART SM00155 422 449 3.6E-7 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 SMART SM00155 238 265 3.2E-6 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 Pfam PF13396 Phospholipase_D-nuclease N-terminal 39 81 1.4E-9 T 14-10-2018 IPR027379 Cardiolipin synthase N-terminal C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 SUPERFAMILY SSF56024 290 493 8.52E-44 T 14-10-2018 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 Gene3D G3DSA:3.30.870.10 336 486 1.3E-27 T 14-10-2018 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 36 509 8.0E-148 T 14-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 SUPERFAMILY SSF56024 95 338 6.59E-51 T 14-10-2018 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 Pfam PF13091 PLD-like domain 351 476 6.5E-26 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 Pfam PF13091 PLD-like domain 155 298 9.9E-15 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 Hamap MF_01916 Cardiolipin synthase. 33 509 40.997 T 14-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 C2I25_08360 dd5731c878508f1fa0a238cb05b33c19 509 Gene3D G3DSA:3.30.870.10 133 335 1.6E-46 T 14-10-2018 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 SMART SM00530 11 65 2.3E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 SUPERFAMILY SSF47413 7 65 8.16E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 Pfam PF13424 Tetratricopeptide repeat 234 301 4.7E-8 T 14-10-2018 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 Pfam PF01381 Helix-turn-helix 15 62 1.0E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 SMART SM00028 270 303 0.0011 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 SMART SM00028 151 184 85.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 SMART SM00028 308 341 45.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 SMART SM00028 229 262 24.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 Gene3D G3DSA:1.10.260.40 4 64 1.3E-12 T 14-10-2018 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 SUPERFAMILY SSF48452 227 351 1.82E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 Gene3D G3DSA:1.25.40.10 167 419 5.2E-53 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_08490 a2c05a7e3311cfe2f598c66876b585db 419 Gene3D G3DSA:1.25.40.1000 65 166 4.7E-56 T 14-10-2018 C2I25_09060 3e6b1d2114a638ab1d5628cfa62243b7 518 Gene3D G3DSA:3.90.550.10 1 238 9.0E-25 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09060 3e6b1d2114a638ab1d5628cfa62243b7 518 SUPERFAMILY SSF53448 5 167 8.59E-23 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09060 3e6b1d2114a638ab1d5628cfa62243b7 518 Pfam PF00535 Glycosyl transferase family 2 10 124 6.3E-16 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_09060 3e6b1d2114a638ab1d5628cfa62243b7 518 Pfam PF00535 Glycosyl transferase family 2 278 390 1.3E-16 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_09060 3e6b1d2114a638ab1d5628cfa62243b7 518 SUPERFAMILY SSF53448 276 434 2.22E-21 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09060 3e6b1d2114a638ab1d5628cfa62243b7 518 Gene3D G3DSA:3.90.550.10 267 414 5.0E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 PRINTS PR00072 Malic enzyme signature 193 215 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 PRINTS PR00072 Malic enzyme signature 277 293 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 PRINTS PR00072 Malic enzyme signature 417 433 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 PRINTS PR00072 Malic enzyme signature 157 186 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 PRINTS PR00072 Malic enzyme signature 95 119 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 PRINTS PR00072 Malic enzyme signature 308 324 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 PRINTS PR00072 Malic enzyme signature 252 270 3.9E-71 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 SMART SM00919 281 539 1.1E-128 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 SMART SM01274 89 271 1.4E-98 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 Pfam PF00390 Malic enzyme, N-terminal domain 89 271 2.2E-73 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 Gene3D G3DSA:3.40.50.720 279 575 2.7E-111 T 14-10-2018 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 Pfam PF03949 Malic enzyme, NAD binding domain 281 538 3.6E-107 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 ProSitePatterns PS00331 Malic enzymes signature. 277 293 - T 14-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 SUPERFAMILY SSF53223 8 280 4.03E-107 T 14-10-2018 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 PIRSF PIRSF000106 3 572 1.9E-229 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 Gene3D G3DSA:3.40.50.10380 23 278 3.4E-108 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 C2I25_02610 2b495dc82ba4a9ef41017e0f24d24ac5 577 SUPERFAMILY SSF51735 281 571 1.61E-97 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_05665 39b11e702433d444208c03e91882f10a 302 SUPERFAMILY SSF56529 82 301 7.59E-75 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I25_05665 39b11e702433d444208c03e91882f10a 302 Gene3D G3DSA:3.90.850.10 88 302 1.7E-87 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I25_05665 39b11e702433d444208c03e91882f10a 302 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 94 301 1.7E-70 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 C2I25_26270 fe61a27d893750afd09302d28de66f8e 141 Pfam PF16219 Domain of unknown function (DUF4879) 30 140 1.0E-26 T 14-10-2018 IPR032624 Protein of unknown function DUF4879 C2I25_16650 171f7b2a70f61a22fc00eac385b35f76 236 Pfam PF12730 ABC-2 family transporter protein 4 182 3.0E-9 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I25_27770 e2352d230afee4d2baf26eb236f9ffea 436 SUPERFAMILY SSF51905 1 423 1.76E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_27770 e2352d230afee4d2baf26eb236f9ffea 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 376 398 7.3E-5 T 14-10-2018 C2I25_27770 e2352d230afee4d2baf26eb236f9ffea 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.3E-5 T 14-10-2018 C2I25_27770 e2352d230afee4d2baf26eb236f9ffea 436 Pfam PF01593 Flavin containing amine oxidoreductase 13 251 3.9E-22 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I25_27770 e2352d230afee4d2baf26eb236f9ffea 436 Gene3D G3DSA:3.50.50.60 8 398 1.0E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_27770 e2352d230afee4d2baf26eb236f9ffea 436 Gene3D G3DSA:3.90.660.50 83 369 1.0E-32 T 14-10-2018 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:1.10.8.60 347 482 6.3E-53 T 14-10-2018 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:3.40.50.300 153 344 4.2E-72 T 14-10-2018 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 SMART SM01086 715 804 5.2E-39 T 14-10-2018 IPR019489 Clp ATPase, C-terminal C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF02151 UvrB/uvrC motif 419 452 3.9E-7 T 14-10-2018 IPR001943 UVR domain GO:0005515 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 SUPERFAMILY SSF81923 5 150 6.75E-33 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF07724 AAA domain (Cdc48 subfamily) 537 709 1.6E-58 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 587 605 7.2E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 663 7.2E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 542 560 7.2E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 616 634 7.2E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 572 590 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 318 1.8E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:4.10.860.10 410 468 6.3E-53 T 14-10-2018 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:1.10.1780.10 1 150 9.8E-62 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:3.40.50.300 491 713 9.5E-91 T 14-10-2018 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:1.10.8.60 715 811 3.5E-28 T 14-10-2018 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 715 793 1.5E-27 T 14-10-2018 IPR019489 Clp ATPase, C-terminal C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 SUPERFAMILY SSF52540 162 470 6.91E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 SMART SM00382 201 345 4.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 SMART SM00382 538 678 7.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.0E-18 T 14-10-2018 IPR004176 Clp, N-terminal C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 69 4.4E-15 T 14-10-2018 IPR004176 Clp, N-terminal C2I25_11120 27dce9a0ddc806a648f863a3ce998893 811 SUPERFAMILY SSF52540 487 804 1.8E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24995 08e1cc2a3ab033c080a019e200df504b 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 9.2E-20 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_24995 08e1cc2a3ab033c080a019e200df504b 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 5.1E-23 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 PIRSF PIRSF002599 1 65 3.1E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 SMART SM00357 2 65 1.7E-30 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 SUPERFAMILY SSF50249 1 64 4.63E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 14-10-2018 IPR019844 Cold-shock conserved site C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 3 18 1.5E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 23 32 1.5E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 38 56 1.5E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 64 1.0E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_03365 ed6a91e3e4f24ef594cc16cead55dd1e 65 Gene3D G3DSA:2.40.50.140 1 64 3.1E-30 T 14-10-2018 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 Gene3D G3DSA:1.20.140.10 428 569 9.8E-27 T 14-10-2018 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 368 387 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 409 6.7E-39 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 SUPERFAMILY SSF56645 19 260 2.09E-73 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 Gene3D G3DSA:1.10.540.10 36 143 8.5E-130 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 141 3.5E-26 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 SUPERFAMILY SSF47203 254 425 4.51E-47 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 147 159 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 237 2.9E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 Gene3D G3DSA:2.40.110.10 144 248 8.5E-130 T 14-10-2018 C2I25_28245 e6bd097838a75cea056759c1d796bfe7 569 Gene3D G3DSA:1.20.140.10 249 406 8.5E-130 T 14-10-2018 C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 360 6.0E-147 T 14-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 Pfam PF00483 Nucleotidyl transferase 9 261 2.1E-71 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 371 48.726 T 14-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 191 201 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 SUPERFAMILY SSF53448 5 342 1.64E-85 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 SUPERFAMILY SSF51161 234 375 4.4E-15 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 Gene3D G3DSA:2.160.10.10 276 375 1.7E-27 T 14-10-2018 C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 100 108 - T 14-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I25_14830 a824ef92cb26b1a250e23a7441b1ae07 376 Gene3D G3DSA:3.90.550.10 1 275 8.0E-94 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 193 212 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 181 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 132 5.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 SUPERFAMILY SSF51735 43 286 9.86E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 Gene3D G3DSA:3.40.50.720 2 284 1.1E-86 T 14-10-2018 C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 180 208 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 231 1.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 132 1.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 212 1.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 63 1.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 183 1.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 248 268 1.1E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07580 2f3449fe23bb168a477c68b1ac444119 288 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 54 284 1.1E-58 T 14-10-2018 C2I25_00470 cfe05fe6214652a49b46eed9e12fb3fc 503 Pfam PF03413 Peptidase propeptide and YPEB domain 122 192 1.5E-8 T 14-10-2018 IPR025711 PepSY domain C2I25_00470 cfe05fe6214652a49b46eed9e12fb3fc 503 SUPERFAMILY SSF55486 242 500 2.38E-40 T 14-10-2018 C2I25_00470 cfe05fe6214652a49b46eed9e12fb3fc 503 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 75 104 1.3E-6 T 14-10-2018 IPR011096 FTP domain C2I25_00470 cfe05fe6214652a49b46eed9e12fb3fc 503 Pfam PF02128 Fungalysin metallopeptidase (M36) 334 501 3.1E-13 T 14-10-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 C2I25_00470 cfe05fe6214652a49b46eed9e12fb3fc 503 Gene3D G3DSA:1.10.390.10 362 503 1.6E-9 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 Gene3D G3DSA:1.10.287.40 1 105 4.2E-26 T 14-10-2018 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 SUPERFAMILY SSF46589 1 113 2.2E-31 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 PIRSF PIRSF001529 1 424 4.8E-193 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 SUPERFAMILY SSF55681 117 423 9.52E-108 T 14-10-2018 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 4.2E-183 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 Gene3D G3DSA:3.30.930.10 106 424 6.1E-132 T 14-10-2018 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.354 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 6.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 6.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 6.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 6.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 6.1E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 3.3E-33 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 C2I25_11565 a4c98779c0c83e0064ce00d4a4316ed3 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 1.1E-39 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_06050 bcbff5822fc57928798f9121ccf8e58e 348 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I25_06050 bcbff5822fc57928798f9121ccf8e58e 348 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I25_06050 bcbff5822fc57928798f9121ccf8e58e 348 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 341 1.5E-124 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I25_06050 bcbff5822fc57928798f9121ccf8e58e 348 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 340 4.0E-126 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I25_06050 bcbff5822fc57928798f9121ccf8e58e 348 Gene3D G3DSA:3.20.20.210 2 347 1.5E-143 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I25_06050 bcbff5822fc57928798f9121ccf8e58e 348 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 342 47.204 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I25_06050 bcbff5822fc57928798f9121ccf8e58e 348 SUPERFAMILY SSF51726 4 343 9.03E-105 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I25_27110 e7644b9afc2d82bc97f3ec7649732183 513 SUPERFAMILY SSF52096 215 490 4.84E-81 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_27110 e7644b9afc2d82bc97f3ec7649732183 513 Gene3D G3DSA:3.90.226.10 249 512 3.7E-83 T 14-10-2018 C2I25_27110 e7644b9afc2d82bc97f3ec7649732183 513 SUPERFAMILY SSF52096 8 253 1.57E-67 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_27110 e7644b9afc2d82bc97f3ec7649732183 513 Pfam PF01039 Carboxyl transferase domain 30 510 3.2E-158 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 C2I25_27110 e7644b9afc2d82bc97f3ec7649732183 513 Gene3D G3DSA:3.90.226.10 2 248 4.6E-77 T 14-10-2018 C2I25_14870 94d51723acdf588ae2add19e36eea4d6 260 Pfam PF01987 Mitochondrial biogenesis AIM24 8 225 9.6E-70 T 14-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 C2I25_14870 94d51723acdf588ae2add19e36eea4d6 260 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 7 232 2.5E-34 T 14-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 C2I25_14870 94d51723acdf588ae2add19e36eea4d6 260 Gene3D G3DSA:3.60.160.10 1 248 3.4E-104 T 14-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily C2I25_14870 94d51723acdf588ae2add19e36eea4d6 260 SUPERFAMILY SSF51219 6 241 7.06E-84 T 14-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily C2I25_22030 c8d789584642458b74684f4ac89ae5ee 362 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 10 360 7.0E-162 T 14-10-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 C2I25_22030 c8d789584642458b74684f4ac89ae5ee 362 Gene3D G3DSA:3.40.50.720 6 196 1.1E-49 T 14-10-2018 C2I25_22030 c8d789584642458b74684f4ac89ae5ee 362 Gene3D G3DSA:3.90.25.10 197 361 1.1E-63 T 14-10-2018 C2I25_22030 c8d789584642458b74684f4ac89ae5ee 362 Pfam PF16363 GDP-mannose 4,6 dehydratase 16 332 1.2E-34 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_22030 c8d789584642458b74684f4ac89ae5ee 362 SUPERFAMILY SSF51735 12 340 1.75E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 Pfam PF07690 Major Facilitator Superfamily 25 273 6.2E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 SUPERFAMILY SSF103473 17 404 1.31E-63 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 PRINTS PR01035 Tetracycline resistance protein signature 60 79 2.0E-39 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 PRINTS PR01035 Tetracycline resistance protein signature 357 380 2.0E-39 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 PRINTS PR01035 Tetracycline resistance protein signature 148 170 2.0E-39 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 PRINTS PR01035 Tetracycline resistance protein signature 265 285 2.0E-39 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 PRINTS PR01035 Tetracycline resistance protein signature 30 46 2.0E-39 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 PRINTS PR01035 Tetracycline resistance protein signature 176 196 2.0E-39 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 PRINTS PR01035 Tetracycline resistance protein signature 118 139 2.0E-39 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 PRINTS PR01035 Tetracycline resistance protein signature 91 115 2.0E-39 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_27685 e9fb9561677c4dc880dd66b61a55c771 411 Gene3D G3DSA:1.20.1250.20 14 405 1.0E-66 T 14-10-2018 C2I25_17360 6042cfdccee3be20d2d85c823f8865cb 213 SUPERFAMILY SSF53335 3 212 1.22E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_17360 6042cfdccee3be20d2d85c823f8865cb 213 Pfam PF01596 O-methyltransferase 40 211 5.4E-35 T 14-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 C2I25_17360 6042cfdccee3be20d2d85c823f8865cb 213 Gene3D G3DSA:3.40.50.150 1 212 2.6E-64 T 14-10-2018 C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Gene3D G3DSA:1.10.10.10 4 70 2.3E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 SMART SM00116 200 248 0.078 T 14-10-2018 IPR000644 CBS domain C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 SMART SM00116 259 307 4.7E-8 T 14-10-2018 IPR000644 CBS domain C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 SUPERFAMILY SSF54637 335 436 3.44E-16 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 SUPERFAMILY SSF46785 5 54 1.7E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 SUPERFAMILY SSF54631 182 306 2.4E-30 T 14-10-2018 C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Pfam PF00571 CBS domain 191 246 1.6E-6 T 14-10-2018 IPR000644 CBS domain C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Pfam PF00571 CBS domain 254 307 2.9E-9 T 14-10-2018 IPR000644 CBS domain C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 SUPERFAMILY SSF75138 72 185 2.49E-29 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Gene3D G3DSA:3.10.580.10 186 314 1.4E-25 T 14-10-2018 C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Gene3D G3DSA:3.40.1390.20 71 178 4.1E-26 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Gene3D G3DSA:3.10.129.10 318 433 1.4E-9 T 14-10-2018 C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Pfam PF03061 Thioesterase superfamily 352 425 7.3E-10 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Pfam PF07085 DRTGG domain 76 178 8.6E-30 T 14-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I25_16245 58538d0e78f65135d3281d65f610e8fb 437 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 58 1.0E-4 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01125 c154c804df281d4cd0dace7f01962e2b 389 Pfam PF00271 Helicase conserved C-terminal domain 232 329 1.8E-25 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_01125 c154c804df281d4cd0dace7f01962e2b 389 Pfam PF00270 DEAD/DEAH box helicase 22 186 2.0E-43 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_01125 c154c804df281d4cd0dace7f01962e2b 389 Gene3D G3DSA:3.40.50.300 204 383 3.9E-42 T 14-10-2018 C2I25_01125 c154c804df281d4cd0dace7f01962e2b 389 SUPERFAMILY SSF52540 66 347 1.18E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01125 c154c804df281d4cd0dace7f01962e2b 389 Gene3D G3DSA:3.40.50.300 3 202 5.2E-63 T 14-10-2018 C2I25_01125 c154c804df281d4cd0dace7f01962e2b 389 SMART SM00490 248 329 6.9E-30 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_01125 c154c804df281d4cd0dace7f01962e2b 389 SMART SM00487 17 213 3.1E-52 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF52777 1058 1230 3.34E-43 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF00668 Condensation domain 1054 1503 3.0E-97 T 14-10-2018 IPR001242 Condensation domain C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF00668 Condensation domain 10 444 1.2E-70 T 14-10-2018 IPR001242 Condensation domain C2I25_28150 952ff048b33645af38021a21e9800706 2385 SMART SM00824 Thioesterase 2135 2293 6.3E-4 T 14-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 C2I25_28150 952ff048b33645af38021a21e9800706 2385 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1672 1683 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF00550 Phosphopantetheine attachment site 975 1036 7.4E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF00550 Phosphopantetheine attachment site 2048 2110 1.7E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF13193 AMP-binding enzyme C-terminal domain 1945 2020 1.1E-12 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 947 1.1E-11 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF53474 2113 2376 5.25E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.30.559.30 207 431 3.7E-60 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.40.50.12780 1512 1931 1.3E-147 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.40.50.12780 452 858 1.3E-135 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF47336 967 1037 4.71E-19 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF00501 AMP-binding enzyme 1525 1937 6.9E-109 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF00501 AMP-binding enzyme 465 864 6.0E-109 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.30.559.10 11 206 9.8E-54 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF56801 1484 2058 4.58E-168 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF56801 431 985 2.49E-159 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.30.300.30 859 961 7.9E-36 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.30.559.10 1057 1429 1.7E-142 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Pfam PF00975 Thioesterase domain 2133 2289 1.0E-30 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.40.50.1820 2036 2378 3.0E-114 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:1.10.1200.10 962 1044 4.8E-25 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF47336 2040 2110 2.09E-20 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF52777 1244 1497 2.11E-59 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.30.559.30 1234 1491 1.7E-142 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF52777 11 184 6.45E-32 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 SMART SM00823 Phosphopantetheine attachment site 2045 2114 1.4E-5 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_28150 952ff048b33645af38021a21e9800706 2385 SMART SM00823 Phosphopantetheine attachment site 972 1041 0.0011 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_28150 952ff048b33645af38021a21e9800706 2385 SUPERFAMILY SSF52777 190 427 2.78E-34 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 Gene3D G3DSA:3.30.300.30 1932 2035 1.1E-36 T 14-10-2018 C2I25_28150 952ff048b33645af38021a21e9800706 2385 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1546 1961 7.5E-140 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_28150 952ff048b33645af38021a21e9800706 2385 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 888 7.5E-137 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 2.4E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 2.4E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 2.4E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 Gene3D G3DSA:1.10.287.130 251 323 1.8E-12 T 14-10-2018 C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 323 8.6E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 SUPERFAMILY SSF47384 244 325 1.26E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 SMART SM00387 369 480 1.4E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 SMART SM00388 258 324 1.9E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 SUPERFAMILY SSF55874 315 478 1.7E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 459 3.5E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_13905 bfb7e7c505384e9b4b652892a674cdfc 480 Gene3D G3DSA:3.30.565.10 329 480 6.4E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_20780 1647b1ed3775cb6f310e42323103551d 354 SUPERFAMILY SSF53756 3 336 4.19E-88 T 14-10-2018 C2I25_20780 1647b1ed3775cb6f310e42323103551d 354 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 353 26.666 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_20780 1647b1ed3775cb6f310e42323103551d 354 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 139 9.7E-34 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_20780 1647b1ed3775cb6f310e42323103551d 354 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 186 334 2.9E-28 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 C2I25_20780 1647b1ed3775cb6f310e42323103551d 354 Gene3D G3DSA:3.40.50.2000 6 161 6.2E-87 T 14-10-2018 C2I25_20780 1647b1ed3775cb6f310e42323103551d 354 Gene3D G3DSA:3.40.50.2000 162 318 6.2E-87 T 14-10-2018 C2I25_17005 8e161812f80ccfe89269c74eedd52dbe 191 PIRSF PIRSF006305 1 190 1.4E-64 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 C2I25_17005 8e161812f80ccfe89269c74eedd52dbe 191 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 182 1.7E-65 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 C2I25_17005 8e161812f80ccfe89269c74eedd52dbe 191 Pfam PF02545 Maf-like protein 3 183 4.3E-61 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 C2I25_17005 8e161812f80ccfe89269c74eedd52dbe 191 Gene3D G3DSA:3.90.950.10 1 188 7.4E-75 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I25_17005 8e161812f80ccfe89269c74eedd52dbe 191 SUPERFAMILY SSF52972 2 183 5.62E-63 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I25_17005 8e161812f80ccfe89269c74eedd52dbe 191 Hamap MF_00528 Septum formation protein Maf [maf]. 3 188 33.374 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 C2I25_09735 dbff3196968ae71931c4e474663f2ca6 483 SUPERFAMILY SSF53720 13 482 2.36E-173 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_09735 dbff3196968ae71931c4e474663f2ca6 483 Pfam PF00171 Aldehyde dehydrogenase family 25 478 1.9E-173 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_09735 dbff3196968ae71931c4e474663f2ca6 483 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 477 1.1E-203 T 14-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 C2I25_09735 dbff3196968ae71931c4e474663f2ca6 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I25_09735 dbff3196968ae71931c4e474663f2ca6 483 Gene3D G3DSA:3.40.309.10 261 451 1.0E-182 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_09735 dbff3196968ae71931c4e474663f2ca6 483 Gene3D G3DSA:3.40.605.10 21 474 1.0E-182 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_10335 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 14-10-2018 IPR025034 Protein of unknown function DUF3948 C2I25_10350 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 14-10-2018 IPR025034 Protein of unknown function DUF3948 C2I25_10345 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 14-10-2018 IPR025034 Protein of unknown function DUF3948 C2I25_08655 adc0ef90633e0c77202a9f39717b9243 365 SUPERFAMILY SSF52540 1 241 7.91E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08655 adc0ef90633e0c77202a9f39717b9243 365 Gene3D G3DSA:3.40.50.300 1 221 6.0E-68 T 14-10-2018 C2I25_08655 adc0ef90633e0c77202a9f39717b9243 365 Gene3D G3DSA:2.40.50.940 222 345 4.9E-25 T 14-10-2018 C2I25_08655 adc0ef90633e0c77202a9f39717b9243 365 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_08655 adc0ef90633e0c77202a9f39717b9243 365 Gene3D G3DSA:2.40.50.140 284 336 4.9E-25 T 14-10-2018 C2I25_08655 adc0ef90633e0c77202a9f39717b9243 365 Pfam PF00005 ABC transporter 20 161 1.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_08655 adc0ef90633e0c77202a9f39717b9243 365 SMART SM00382 28 211 3.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08655 adc0ef90633e0c77202a9f39717b9243 365 SUPERFAMILY SSF50331 236 352 7.78E-21 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I25_14595 507215c385e6b8fb5092aed60a59f5dc 207 SUPERFAMILY SSF53098 4 178 3.52E-31 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_14595 507215c385e6b8fb5092aed60a59f5dc 207 SMART SM00479 5 182 3.0E-32 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_14595 507215c385e6b8fb5092aed60a59f5dc 207 Gene3D G3DSA:3.30.420.10 2 197 3.9E-40 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_14595 507215c385e6b8fb5092aed60a59f5dc 207 Pfam PF00929 Exonuclease 8 173 1.9E-22 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_10090 a6aa99ec225d778e4151be121515ddc7 233 Gene3D G3DSA:1.10.10.10 131 233 3.0E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_10090 a6aa99ec225d778e4151be121515ddc7 233 SUPERFAMILY SSF52172 5 188 9.81E-41 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_10090 a6aa99ec225d778e4151be121515ddc7 233 SMART SM00862 153 229 2.7E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_10090 a6aa99ec225d778e4151be121515ddc7 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 6.3E-30 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_10090 a6aa99ec225d778e4151be121515ddc7 233 Gene3D G3DSA:3.40.50.2300 2 130 1.2E-37 T 14-10-2018 C2I25_10090 a6aa99ec225d778e4151be121515ddc7 233 SMART SM00448 4 114 2.1E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_10090 a6aa99ec225d778e4151be121515ddc7 233 Pfam PF00072 Response regulator receiver domain 6 115 8.1E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_05860 97941fab1d50f9b1ce9de031a4093a19 368 Pfam PF00149 Calcineurin-like phosphoesterase 148 311 5.2E-12 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_05860 97941fab1d50f9b1ce9de031a4093a19 368 Gene3D G3DSA:3.60.21.10 146 338 1.7E-22 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_05860 97941fab1d50f9b1ce9de031a4093a19 368 SUPERFAMILY SSF56300 145 366 1.22E-33 T 14-10-2018 C2I25_09870 e15b1e899b72d91b042440538dc04f28 54 Gene3D G3DSA:1.10.1220.10 1 50 1.1E-11 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 C2I25_09870 e15b1e899b72d91b042440538dc04f28 54 SUPERFAMILY SSF47598 2 47 2.06E-11 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 C2I25_09870 e15b1e899b72d91b042440538dc04f28 54 Pfam PF05534 HicB family 4 38 3.9E-5 T 14-10-2018 IPR008651 Uncharacterised protein family HicB C2I25_20455 699b3bd8dbe230381f7a7773d7a68f6f 93 Pfam PF04456 Protein of unknown function (DUF503) 3 87 1.4E-29 T 14-10-2018 IPR007546 Protein of unknown function DUF503 C2I25_20455 699b3bd8dbe230381f7a7773d7a68f6f 93 SUPERFAMILY SSF103007 1 93 7.19E-32 T 14-10-2018 IPR036746 TT1725-like superfamily C2I25_20455 699b3bd8dbe230381f7a7773d7a68f6f 93 Gene3D G3DSA:3.30.70.1120 1 93 1.4E-23 T 14-10-2018 IPR036746 TT1725-like superfamily C2I25_22250 413162285311610a29852c207f6f2495 140 Hamap MF_01048 Protein PsiE [psiE]. 5 138 26.008 T 14-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 C2I25_22250 413162285311610a29852c207f6f2495 140 Pfam PF06146 Phosphate-starvation-inducible E 60 124 7.6E-17 T 14-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like C2I25_22250 413162285311610a29852c207f6f2495 140 PIRSF PIRSF029598 4 140 3.5E-52 T 14-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 C2I25_15325 01fe37c9a0f904b0a80fa647e58ad9f7 689 Pfam PF00884 Sulfatase 327 622 1.0E-32 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I25_15325 01fe37c9a0f904b0a80fa647e58ad9f7 689 Gene3D G3DSA:3.40.720.10 320 628 1.2E-41 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_15325 01fe37c9a0f904b0a80fa647e58ad9f7 689 SUPERFAMILY SSF53649 399 577 5.45E-20 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_21290 ea1878160895abf2970ee627161502e9 269 Gene3D G3DSA:3.30.70.120 181 257 2.1E-21 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_21290 ea1878160895abf2970ee627161502e9 269 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 4 204 4.3E-62 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_21290 ea1878160895abf2970ee627161502e9 269 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 210 264 1.3E-21 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_21290 ea1878160895abf2970ee627161502e9 269 PIRSF PIRSF006483 1 269 4.9E-87 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_19675 c3b72507932329ed9bf72882080fc018 276 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 247 55.419 T 14-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 C2I25_19675 c3b72507932329ed9bf72882080fc018 276 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 24 238 3.0E-124 T 14-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 C2I25_24130 29e4fc82c51e70a55010125da26a513b 868 Gene3D G3DSA:3.30.470.20 185 314 2.5E-46 T 14-10-2018 C2I25_24130 29e4fc82c51e70a55010125da26a513b 868 Pfam PF00391 PEP-utilising enzyme, mobile domain 792 863 1.6E-21 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 C2I25_24130 29e4fc82c51e70a55010125da26a513b 868 Gene3D G3DSA:3.50.30.10 765 868 3.8E-32 T 14-10-2018 C2I25_24130 29e4fc82c51e70a55010125da26a513b 868 SUPERFAMILY SSF56059 1 341 8.71E-95 T 14-10-2018 C2I25_24130 29e4fc82c51e70a55010125da26a513b 868 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 314 6.7E-94 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 C2I25_24130 29e4fc82c51e70a55010125da26a513b 868 Gene3D G3DSA:3.30.1490.20 1 184 1.7E-68 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I25_24130 29e4fc82c51e70a55010125da26a513b 868 SUPERFAMILY SSF52009 759 866 1.27E-27 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 SUPERFAMILY SSF55785 334 451 3.43E-15 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 Gene3D G3DSA:3.20.20.450 639 890 1.9E-96 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 SMART SM00267 453 625 6.6E-75 T 14-10-2018 IPR000160 GGDEF domain C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 SUPERFAMILY SSF55073 469 627 9.42E-55 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 Pfam PF00989 PAS fold 342 450 6.3E-9 T 14-10-2018 IPR013767 PAS fold GO:0006355 C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 SUPERFAMILY SSF141868 640 888 2.48E-86 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 Gene3D G3DSA:3.30.450.20 328 451 9.3E-17 T 14-10-2018 C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 Pfam PF00990 Diguanylate cyclase, GGDEF domain 464 621 7.0E-54 T 14-10-2018 IPR000160 GGDEF domain C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 Pfam PF13321 Domain of unknown function (DUF4084) 1 304 2.9E-180 T 14-10-2018 IPR025152 Domain of unknown function DUF4084 C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 Pfam PF00563 EAL domain 642 876 4.1E-73 T 14-10-2018 IPR001633 EAL domain C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 338 458 2.1E-12 T 14-10-2018 IPR000014 PAS domain C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 Gene3D G3DSA:3.30.70.270 458 638 5.3E-66 T 14-10-2018 C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 461 623 1.1E-48 T 14-10-2018 IPR000160 GGDEF domain C2I25_12425 24524316721d14a2fa3b6ad5a973ad1c 892 SMART SM00052 635 881 2.5E-117 T 14-10-2018 IPR001633 EAL domain C2I25_27455 d875594daa7aa6d3656ee8120287920c 92 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 52 1.6E-11 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_27455 d875594daa7aa6d3656ee8120287920c 92 SMART SM00966 8 51 2.0E-8 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_27455 d875594daa7aa6d3656ee8120287920c 92 SUPERFAMILY SSF89447 1 50 4.32E-14 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I25_27455 d875594daa7aa6d3656ee8120287920c 92 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 48 1.9E-9 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_27455 d875594daa7aa6d3656ee8120287920c 92 Gene3D G3DSA:2.10.260.10 1 54 1.3E-21 T 14-10-2018 C2I25_04805 51c08a3d87dcf9b36e645bc1666a23ef 358 SUPERFAMILY SSF53850 40 348 1.13E-70 T 14-10-2018 C2I25_04805 51c08a3d87dcf9b36e645bc1666a23ef 358 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 8 355 8.0E-163 T 14-10-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative C2I25_04805 51c08a3d87dcf9b36e645bc1666a23ef 358 Gene3D G3DSA:3.40.190.10 145 332 2.3E-90 T 14-10-2018 C2I25_04805 51c08a3d87dcf9b36e645bc1666a23ef 358 Gene3D G3DSA:3.40.190.10 44 319 2.3E-90 T 14-10-2018 C2I25_04805 51c08a3d87dcf9b36e645bc1666a23ef 358 Pfam PF13343 Bacterial extracellular solute-binding protein 90 334 1.5E-31 T 14-10-2018 C2I25_04805 51c08a3d87dcf9b36e645bc1666a23ef 358 PIRSF PIRSF002825 1 351 3.1E-93 T 14-10-2018 IPR026045 Ferric binding protein C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 SUPERFAMILY SSF103473 6 564 1.03E-66 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 Gene3D G3DSA:1.20.1720.10 9 218 2.9E-42 T 14-10-2018 C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 Gene3D G3DSA:1.20.1250.20 261 454 2.0E-13 T 14-10-2018 C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 8.2E-11 T 14-10-2018 C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 8.2E-11 T 14-10-2018 C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 8.2E-11 T 14-10-2018 C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 8.2E-11 T 14-10-2018 C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 Pfam PF07690 Major Facilitator Superfamily 14 405 5.2E-49 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_02520 472af7af33e880e9349ba1ad19157fbf 582 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 455 1.2E-74 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_13495 6d9374df287699d931e58d8b82b2e39a 158 Gene3D G3DSA:1.20.1250.20 8 156 7.7E-6 T 14-10-2018 C2I25_13495 6d9374df287699d931e58d8b82b2e39a 158 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 13 152 4.2E-64 T 14-10-2018 IPR014203 Sporulation stage V, protein AC C2I25_13495 6d9374df287699d931e58d8b82b2e39a 158 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 31 148 3.3E-38 T 14-10-2018 IPR005562 SpoVA C2I25_10910 b00cbd747107e84b39e53669dd31a287 179 Gene3D G3DSA:3.30.1440.10 1 179 1.0E-83 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10910 b00cbd747107e84b39e53669dd31a287 179 SUPERFAMILY SSF55282 3 178 6.12E-78 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10910 b00cbd747107e84b39e53669dd31a287 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.015 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10910 b00cbd747107e84b39e53669dd31a287 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.0E-42 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10910 b00cbd747107e84b39e53669dd31a287 179 PIRSF PIRSF002161 1 179 1.9E-69 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10910 b00cbd747107e84b39e53669dd31a287 179 Pfam PF00281 Ribosomal protein L5 24 80 2.0E-28 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10910 b00cbd747107e84b39e53669dd31a287 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 14-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_13020 8ff51454ba1051f0df33bb154ccb9243 251 Pfam PF00990 Diguanylate cyclase, GGDEF domain 132 227 9.0E-5 T 14-10-2018 IPR000160 GGDEF domain C2I25_13020 8ff51454ba1051f0df33bb154ccb9243 251 Gene3D G3DSA:3.30.70.270 114 242 1.9E-6 T 14-10-2018 C2I25_13020 8ff51454ba1051f0df33bb154ccb9243 251 SUPERFAMILY SSF55073 131 227 1.8E-5 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 Gene3D G3DSA:1.20.1480.50 291 388 3.6E-14 T 14-10-2018 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 Gene3D G3DSA:3.30.565.10 468 617 4.3E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 Pfam PF00672 HAMP domain 331 378 5.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 Pfam PF00512 His Kinase A (phospho-acceptor) domain 398 462 6.3E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 Gene3D G3DSA:1.10.287.130 389 467 3.1E-19 T 14-10-2018 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 SMART SM00388 397 462 1.5E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 SUPERFAMILY SSF47384 383 462 2.35E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 508 615 6.5E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 SMART SM00387 506 617 8.7E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 SMART SM00304 330 382 9.9E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 SUPERFAMILY SSF158472 331 381 4.45E-9 T 14-10-2018 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 SUPERFAMILY SSF55874 452 615 7.33E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 571 8.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 614 8.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 557 8.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15135 193d83f7326bc2612a84ebe91125c156 617 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 596 8.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_10360 b31f0319a70b207b13387c35e7ce19a7 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 1.6E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_10360 b31f0319a70b207b13387c35e7ce19a7 321 Pfam PF00005 ABC transporter 33 184 3.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10360 b31f0319a70b207b13387c35e7ce19a7 321 Gene3D G3DSA:3.40.50.300 3 321 9.4E-102 T 14-10-2018 C2I25_10360 b31f0319a70b207b13387c35e7ce19a7 321 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10360 b31f0319a70b207b13387c35e7ce19a7 321 SMART SM00382 41 233 8.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_10360 b31f0319a70b207b13387c35e7ce19a7 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 1.9E-29 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_10360 b31f0319a70b207b13387c35e7ce19a7 321 SUPERFAMILY SSF52540 40 316 1.01E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23095 4641e59f7bd905bec9c83064a9156f09 350 Pfam PF00480 ROK family 129 243 1.0E-16 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I25_23095 4641e59f7bd905bec9c83064a9156f09 350 SUPERFAMILY SSF53067 93 261 2.53E-17 T 14-10-2018 C2I25_23095 4641e59f7bd905bec9c83064a9156f09 350 Gene3D G3DSA:1.10.10.10 20 86 1.3E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23095 4641e59f7bd905bec9c83064a9156f09 350 Gene3D G3DSA:3.30.420.40 208 246 1.9E-28 T 14-10-2018 C2I25_23095 4641e59f7bd905bec9c83064a9156f09 350 Gene3D G3DSA:3.30.420.40 95 207 1.9E-28 T 14-10-2018 C2I25_23095 4641e59f7bd905bec9c83064a9156f09 350 SUPERFAMILY SSF46785 22 86 8.53E-8 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_24265 908a2d72455c4124b7f1117e9f3f547f 191 SUPERFAMILY SSF53335 2 188 1.87E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_24265 908a2d72455c4124b7f1117e9f3f547f 191 Pfam PF04989 Cephalosporin hydroxylase 3 190 1.0E-69 T 14-10-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 C2I25_24265 908a2d72455c4124b7f1117e9f3f547f 191 Gene3D G3DSA:3.40.50.150 15 180 5.5E-38 T 14-10-2018 C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 14-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 14-10-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 PIRSF PIRSF000303 1 160 1.1E-68 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 SUPERFAMILY SSF52833 1 158 5.99E-64 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 Gene3D G3DSA:3.40.30.10 1 160 8.3E-73 T 14-10-2018 C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 Pfam PF00255 Glutathione peroxidase 3 109 6.3E-44 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.1E-21 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.1E-21 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I25_01075 2aca70a57d40829106af8b56858b4ade 160 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.1E-21 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I25_18560 998fc4ecd6e044d5a07d824def70fac7 242 Gene3D G3DSA:3.20.20.190 1 239 4.0E-83 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_18560 998fc4ecd6e044d5a07d824def70fac7 242 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 233 2.7E-42 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I25_18560 998fc4ecd6e044d5a07d824def70fac7 242 SUPERFAMILY SSF51695 1 237 6.54E-74 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_21645 ae049f25b10d671923f860d2ad607a9d 568 SUPERFAMILY SSF53850 54 563 2.64E-125 T 14-10-2018 C2I25_21645 ae049f25b10d671923f860d2ad607a9d 568 Gene3D G3DSA:3.40.190.10 69 553 3.2E-183 T 14-10-2018 C2I25_21645 ae049f25b10d671923f860d2ad607a9d 568 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 485 4.7E-80 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_21645 ae049f25b10d671923f860d2ad607a9d 568 Gene3D G3DSA:3.10.105.10 311 538 3.2E-183 T 14-10-2018 C2I25_21645 ae049f25b10d671923f860d2ad607a9d 568 Gene3D G3DSA:3.90.76.10 88 210 3.2E-183 T 14-10-2018 C2I25_21645 ae049f25b10d671923f860d2ad607a9d 568 PIRSF PIRSF002741 2 568 1.4E-107 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 Gene3D G3DSA:3.30.565.10 318 470 1.1E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 471 6.3E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 SUPERFAMILY SSF47384 233 313 1.96E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 SUPERFAMILY SSF55874 304 470 6.02E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 Gene3D G3DSA:1.10.287.130 240 316 4.9E-15 T 14-10-2018 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 311 2.7E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 SMART SM00388 246 313 7.4E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 SMART SM00304 186 238 2.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 Pfam PF00672 HAMP domain 187 234 1.7E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 SMART SM00387 363 474 3.8E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 Gene3D G3DSA:1.20.1480.50 148 239 5.8E-7 T 14-10-2018 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 4.8E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 4.8E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 4.8E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21405 26824e9b3cbf4c3026ca17297c746c6c 484 SUPERFAMILY SSF158472 188 235 1.12E-8 T 14-10-2018 C2I25_23165 dfab9b6b7a6a74b4e6b76e8e216286b0 241 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_23165 dfab9b6b7a6a74b4e6b76e8e216286b0 241 SUPERFAMILY SSF52540 1 225 3.85E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23165 dfab9b6b7a6a74b4e6b76e8e216286b0 241 Gene3D G3DSA:3.40.50.300 1 239 1.2E-61 T 14-10-2018 C2I25_23165 dfab9b6b7a6a74b4e6b76e8e216286b0 241 SMART SM00382 27 211 2.3E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_23165 dfab9b6b7a6a74b4e6b76e8e216286b0 241 Pfam PF00005 ABC transporter 19 161 7.9E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_12770 8a7d990fd2a34c221d96df6b875254a6 301 SUPERFAMILY SSF51261 105 215 4.29E-27 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_12770 8a7d990fd2a34c221d96df6b875254a6 301 Gene3D G3DSA:2.70.70.10 70 227 4.7E-46 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_12770 8a7d990fd2a34c221d96df6b875254a6 301 Pfam PF01551 Peptidase family M23 113 211 9.6E-23 T 14-10-2018 IPR016047 Peptidase M23 C2I25_27975 9dc3ac1da81cc644ac5d332b8a15e87b 216 SMART SM01059 1 205 1.5E-110 T 14-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 C2I25_27975 9dc3ac1da81cc644ac5d332b8a15e87b 216 PIRSF PIRSF000440 1 214 1.7E-85 T 14-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 C2I25_27975 9dc3ac1da81cc644ac5d332b8a15e87b 216 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 9 204 3.0E-106 T 14-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 C2I25_27975 9dc3ac1da81cc644ac5d332b8a15e87b 216 SUPERFAMILY SSF52777 1 211 1.52E-73 T 14-10-2018 C2I25_27975 9dc3ac1da81cc644ac5d332b8a15e87b 216 Gene3D G3DSA:3.30.559.10 1 208 5.7E-68 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27975 9dc3ac1da81cc644ac5d332b8a15e87b 216 Pfam PF00302 Chloramphenicol acetyltransferase 3 205 3.6E-85 T 14-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 C2I25_06880 aebbbba529a02f8fa8c54a2b826f984b 325 SUPERFAMILY SSF51735 1 325 3.03E-96 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_06880 aebbbba529a02f8fa8c54a2b826f984b 325 PIRSF PIRSF001439 1 325 2.9E-93 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 C2I25_06880 aebbbba529a02f8fa8c54a2b826f984b 325 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 4 317 1.5E-85 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 C2I25_06880 aebbbba529a02f8fa8c54a2b826f984b 325 Gene3D G3DSA:3.40.50.720 124 298 6.0E-102 T 14-10-2018 C2I25_06880 aebbbba529a02f8fa8c54a2b826f984b 325 Gene3D G3DSA:3.30.1780.10 5 320 6.0E-102 T 14-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 C2I25_23610 9654755f9905cb5156fa60ec61d941b9 596 Pfam PF00326 Prolyl oligopeptidase family 390 595 2.3E-42 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 C2I25_23610 9654755f9905cb5156fa60ec61d941b9 596 SUPERFAMILY SSF69304 22 294 3.01E-16 T 14-10-2018 C2I25_23610 9654755f9905cb5156fa60ec61d941b9 596 Gene3D G3DSA:2.120.10.30 12 203 4.0E-8 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I25_23610 9654755f9905cb5156fa60ec61d941b9 596 Gene3D G3DSA:3.40.50.1820 303 596 8.8E-66 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_23610 9654755f9905cb5156fa60ec61d941b9 596 SUPERFAMILY SSF53474 345 595 7.13E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_21275 6f907201586388b2131efd474ae59c6b 510 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 397 502 1.4E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21275 6f907201586388b2131efd474ae59c6b 510 Gene3D G3DSA:3.30.450.20 29 139 5.5E-16 T 14-10-2018 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 280 2.3E-10 T 14-10-2018 IPR000014 PAS domain C2I25_21275 6f907201586388b2131efd474ae59c6b 510 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 150 8.8E-17 T 14-10-2018 IPR000014 PAS domain C2I25_21275 6f907201586388b2131efd474ae59c6b 510 SMART SM00387 396 503 1.3E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21275 6f907201586388b2131efd474ae59c6b 510 Pfam PF08448 PAS fold 162 276 3.1E-11 T 14-10-2018 IPR013656 PAS fold-4 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 3.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 462 3.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 500 3.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 448 3.2E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 SUPERFAMILY SSF55874 348 501 1.44E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21275 6f907201586388b2131efd474ae59c6b 510 SUPERFAMILY SSF47384 283 351 8.04E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 SMART SM00388 290 354 1.8E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 Gene3D G3DSA:1.10.287.130 278 353 9.6E-19 T 14-10-2018 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 Gene3D G3DSA:3.30.450.20 144 277 1.8E-17 T 14-10-2018 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 Pfam PF00512 His Kinase A (phospho-acceptor) domain 292 350 2.1E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_21275 6f907201586388b2131efd474ae59c6b 510 SMART SM00091 32 98 1.9E-11 T 14-10-2018 IPR000014 PAS domain C2I25_21275 6f907201586388b2131efd474ae59c6b 510 SMART SM00091 156 221 0.19 T 14-10-2018 IPR000014 PAS domain C2I25_21275 6f907201586388b2131efd474ae59c6b 510 SUPERFAMILY SSF55785 17 137 1.08E-15 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_21275 6f907201586388b2131efd474ae59c6b 510 Gene3D G3DSA:3.30.565.10 355 507 8.3E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21275 6f907201586388b2131efd474ae59c6b 510 SUPERFAMILY SSF55785 145 273 1.52E-15 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_21275 6f907201586388b2131efd474ae59c6b 510 Pfam PF13426 PAS domain 42 138 9.7E-9 T 14-10-2018 IPR000014 PAS domain C2I25_17840 ba5a2a61c421627eb7a9575934230159 373 SUPERFAMILY SSF102705 6 372 5.1E-136 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily C2I25_17840 ba5a2a61c421627eb7a9575934230159 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 352 6.5E-85 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 C2I25_17840 ba5a2a61c421627eb7a9575934230159 373 Gene3D G3DSA:3.30.70.120 133 242 3.1E-47 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_17840 ba5a2a61c421627eb7a9575934230159 373 PIRSF PIRSF037489 4 373 2.4E-162 T 14-10-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria C2I25_17840 ba5a2a61c421627eb7a9575934230159 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 6 368 2.2E-88 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 C2I25_17840 ba5a2a61c421627eb7a9575934230159 373 Gene3D G3DSA:3.40.1390.30 5 129 7.5E-40 T 14-10-2018 C2I25_00365 5a4e7a14c82e88e0e242630b2ab59150 265 Hamap MF_02077 Lipid II flippase Amj [amj]. 2 262 25.528 T 14-10-2018 IPR021260 Lipid II flippase Amj C2I25_00365 5a4e7a14c82e88e0e242630b2ab59150 265 Pfam PF10997 Alternate to MurJ 11 260 2.5E-92 T 14-10-2018 IPR021260 Lipid II flippase Amj C2I25_21440 bbff613cd9d320c045d578c7744208aa 147 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_21440 bbff613cd9d320c045d578c7744208aa 147 PRINTS PR00502 NUDIX hydrolase family signature 45 60 3.8E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_21440 bbff613cd9d320c045d578c7744208aa 147 PRINTS PR00502 NUDIX hydrolase family signature 31 45 3.8E-9 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_21440 bbff613cd9d320c045d578c7744208aa 147 SUPERFAMILY SSF55811 9 126 2.98E-24 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_21440 bbff613cd9d320c045d578c7744208aa 147 Gene3D G3DSA:3.90.79.10 6 146 2.2E-40 T 14-10-2018 C2I25_21440 bbff613cd9d320c045d578c7744208aa 147 Pfam PF00293 NUDIX domain 8 118 6.0E-18 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_09500 307d5c02591153d3abefa62adf198946 430 Gene3D G3DSA:1.20.1480.50 43 126 2.3E-10 T 14-10-2018 C2I25_09500 307d5c02591153d3abefa62adf198946 430 SMART SM00283 147 429 1.8E-52 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_09500 307d5c02591153d3abefa62adf198946 430 SUPERFAMILY SSF58104 101 428 4.97E-64 T 14-10-2018 C2I25_09500 307d5c02591153d3abefa62adf198946 430 SMART SM00304 72 125 5.7E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_09500 307d5c02591153d3abefa62adf198946 430 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 227 382 4.4E-38 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_09500 307d5c02591153d3abefa62adf198946 430 Gene3D G3DSA:1.10.287.950 127 429 5.3E-61 T 14-10-2018 C2I25_09500 307d5c02591153d3abefa62adf198946 430 Pfam PF00672 HAMP domain 74 121 2.9E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_02270 775a3c2ff99369be865eba0498017d73 359 SUPERFAMILY SSF58100 34 356 8.89E-99 T 14-10-2018 C2I25_02270 775a3c2ff99369be865eba0498017d73 359 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 47 223 2.2E-59 T 14-10-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 C2I25_02270 775a3c2ff99369be865eba0498017d73 359 Gene3D G3DSA:1.20.1170.10 41 359 6.0E-111 T 14-10-2018 C2I25_25410 a21fc437c322ef525b6163ab399590ab 345 PIRSF PIRSF029792 1 334 9.1E-144 T 14-10-2018 IPR008794 Proline racemase family C2I25_25410 a21fc437c322ef525b6163ab399590ab 345 Pfam PF05544 Proline racemase 10 331 9.9E-119 T 14-10-2018 IPR008794 Proline racemase family C2I25_25410 a21fc437c322ef525b6163ab399590ab 345 Gene3D G3DSA:3.10.310.10 146 310 6.5E-125 T 14-10-2018 C2I25_25410 a21fc437c322ef525b6163ab399590ab 345 SUPERFAMILY SSF54506 1 331 4.57E-113 T 14-10-2018 C2I25_25410 a21fc437c322ef525b6163ab399590ab 345 Gene3D G3DSA:3.10.310.10 7 333 6.5E-125 T 14-10-2018 C2I25_05770 64b8293c9897905f943c42c095cb61c7 220 Pfam PF00395 S-layer homology domain 42 84 1.1E-10 T 14-10-2018 IPR001119 S-layer homology domain C2I25_05770 64b8293c9897905f943c42c095cb61c7 220 Pfam PF00395 S-layer homology domain 162 205 6.6E-10 T 14-10-2018 IPR001119 S-layer homology domain C2I25_05770 64b8293c9897905f943c42c095cb61c7 220 Pfam PF00395 S-layer homology domain 102 146 5.5E-11 T 14-10-2018 IPR001119 S-layer homology domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Gene3D G3DSA:2.60.40.1850 179 322 8.9E-45 T 14-10-2018 C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Gene3D G3DSA:2.60.40.1850 376 515 9.9E-51 T 14-10-2018 C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Gene3D G3DSA:2.60.40.1850 20 153 3.7E-48 T 14-10-2018 C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Gene3D G3DSA:2.60.40.1850 580 708 1.2E-49 T 14-10-2018 C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Gene3D G3DSA:2.60.40.1850 732 859 6.5E-50 T 14-10-2018 C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SUPERFAMILY SSF158911 15 160 7.85E-50 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SUPERFAMILY SSF158911 734 864 1.44E-47 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SUPERFAMILY SSF158911 582 717 9.29E-48 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Pfam PF05031 Iron Transport-associated domain 194 310 7.0E-33 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Pfam PF05031 Iron Transport-associated domain 589 704 4.4E-37 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Pfam PF05031 Iron Transport-associated domain 740 856 1.7E-36 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Pfam PF05031 Iron Transport-associated domain 32 147 4.1E-37 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 Pfam PF05031 Iron Transport-associated domain 393 509 5.4E-38 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SUPERFAMILY SSF158911 185 323 3.4E-43 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 915 943 5.3E-13 T 14-10-2018 IPR017502 Sortase B cell surface sorting signal C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SUPERFAMILY SSF158911 391 522 1.44E-48 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SMART SM00725 741 862 6.7E-42 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SMART SM00725 395 516 3.1E-45 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SMART SM00725 590 711 3.0E-43 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SMART SM00725 196 317 4.3E-31 T 14-10-2018 IPR006635 NEAT domain C2I25_16585 7ad228877a0e94f908067b1f6c5a372b 947 SMART SM00725 33 154 9.1E-47 T 14-10-2018 IPR006635 NEAT domain C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 Gene3D G3DSA:3.30.450.20 61 274 8.9E-36 T 14-10-2018 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 Pfam PF02743 Cache domain 47 266 8.6E-30 T 14-10-2018 IPR033479 Double Cache domain 1 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 Gene3D G3DSA:1.10.8.500 302 355 5.7E-12 T 14-10-2018 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 1.2E-5 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 511 540 1.2E-5 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 Gene3D G3DSA:3.30.450.20 72 183 8.9E-36 T 14-10-2018 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 Pfam PF00672 HAMP domain 303 352 4.4E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 SMART SM00304 303 355 5.8E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 432 611 1.7E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 SMART SM00283 384 659 4.3E-75 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 Gene3D G3DSA:1.10.287.950 364 659 3.6E-70 T 14-10-2018 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 SUPERFAMILY SSF58104 323 659 3.14E-72 T 14-10-2018 C2I25_08610 9b97e4fc9fda98e6038eba049b4b5120 660 SUPERFAMILY SSF103190 98 190 2.12E-13 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_04830 4ea15276bcc24057c85acbd7d1ae2c91 397 Gene3D G3DSA:3.50.50.60 30 386 5.5E-59 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_04830 4ea15276bcc24057c85acbd7d1ae2c91 397 Gene3D G3DSA:3.30.9.10 122 343 5.5E-59 T 14-10-2018 C2I25_04830 4ea15276bcc24057c85acbd7d1ae2c91 397 SUPERFAMILY SSF51905 28 387 9.06E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_04830 4ea15276bcc24057c85acbd7d1ae2c91 397 Pfam PF01266 FAD dependent oxidoreductase 29 380 1.2E-42 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I25_12685 0db198c027c4dec5dda5d401879abbb5 172 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 20 161 7.4E-73 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12685 0db198c027c4dec5dda5d401879abbb5 172 Gene3D G3DSA:3.40.50.12280 5 172 1.1E-77 T 14-10-2018 C2I25_12685 0db198c027c4dec5dda5d401879abbb5 172 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 10 160 43.172 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12685 0db198c027c4dec5dda5d401879abbb5 172 SUPERFAMILY SSF56770 18 164 4.19E-67 T 14-10-2018 C2I25_12685 0db198c027c4dec5dda5d401879abbb5 172 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 155 3.4E-26 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12465 8198f2de2843536af9cb6a303b265147 209 SUPERFAMILY SSF48498 92 203 1.26E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_12465 8198f2de2843536af9cb6a303b265147 209 SUPERFAMILY SSF46689 18 88 4.14E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_12465 8198f2de2843536af9cb6a303b265147 209 Gene3D G3DSA:1.10.357.10 61 205 7.8E-17 T 14-10-2018 C2I25_12465 8198f2de2843536af9cb6a303b265147 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 6.4E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_12465 8198f2de2843536af9cb6a303b265147 209 Gene3D G3DSA:1.10.10.60 17 59 3.7E-15 T 14-10-2018 C2I25_12465 8198f2de2843536af9cb6a303b265147 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_12465 8198f2de2843536af9cb6a303b265147 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.7E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_17345 a175795613beff871f303cd61bca28c0 137 SMART SM00732 1 103 2.2E-42 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 C2I25_17345 a175795613beff871f303cd61bca28c0 137 Gene3D G3DSA:3.30.420.140 1 137 1.7E-53 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 C2I25_17345 a175795613beff871f303cd61bca28c0 137 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 137 25.841 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 C2I25_17345 a175795613beff871f303cd61bca28c0 137 SUPERFAMILY SSF53098 1 136 5.01E-47 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_17345 a175795613beff871f303cd61bca28c0 137 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 9.8E-53 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 C2I25_17345 a175795613beff871f303cd61bca28c0 137 Pfam PF03652 Holliday junction resolvase 1 135 1.6E-47 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 C2I25_08145 8ac714e12fd07d5f4e48b6b36f143abe 799 Pfam PF05547 Immune inhibitor A peptidase M6 153 795 0.0 T 14-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I25_08145 8ac714e12fd07d5f4e48b6b36f143abe 799 PIRSF PIRSF007519 1 799 0.0 T 14-10-2018 IPR012300 Peptidase M6, InhA C2I25_08145 8ac714e12fd07d5f4e48b6b36f143abe 799 SUPERFAMILY SSF55486 266 435 3.04E-17 T 14-10-2018 C2I25_08145 8ac714e12fd07d5f4e48b6b36f143abe 799 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 188 497 9.9E-86 T 14-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 Gene3D G3DSA:3.40.640.10 93 457 2.9E-116 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 9.1E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 9.1E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 Pfam PF00155 Aminotransferase class I and II 135 456 5.0E-13 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 SUPERFAMILY SSF46785 9 83 1.3E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 9.6E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 SMART SM00345 20 79 5.4E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 Gene3D G3DSA:1.10.10.10 2 90 3.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_08575 c89abb274c1154c2259609f84b896aa1 466 SUPERFAMILY SSF53383 75 462 2.27E-73 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 250 8.1E-72 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 Gene3D G3DSA:3.30.420.40 5 251 2.4E-83 T 14-10-2018 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 368 388 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 PIRSF PIRSF000538 5 506 1.2E-149 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 SUPERFAMILY SSF53067 259 502 1.21E-67 T 14-10-2018 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 SUPERFAMILY SSF53067 7 253 9.88E-72 T 14-10-2018 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 7 511 1.1E-197 T 14-10-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 455 6.4E-38 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 C2I25_00115 e0cadbd7270d3ae4c53ea577acc9f931 513 Gene3D G3DSA:3.30.420.40 253 513 2.7E-88 T 14-10-2018 C2I25_23925 47ca794060750b634ab3c34f1aeeff5a 185 PRINTS PR01754 Streptothricin acetyltransferase signature 103 118 1.2E-19 T 14-10-2018 IPR008125 Streptothricin acetyltransferase C2I25_23925 47ca794060750b634ab3c34f1aeeff5a 185 PRINTS PR01754 Streptothricin acetyltransferase signature 127 142 1.2E-19 T 14-10-2018 IPR008125 Streptothricin acetyltransferase C2I25_23925 47ca794060750b634ab3c34f1aeeff5a 185 PRINTS PR01754 Streptothricin acetyltransferase signature 171 184 1.2E-19 T 14-10-2018 IPR008125 Streptothricin acetyltransferase C2I25_23925 47ca794060750b634ab3c34f1aeeff5a 185 PRINTS PR01754 Streptothricin acetyltransferase signature 148 164 1.2E-19 T 14-10-2018 IPR008125 Streptothricin acetyltransferase C2I25_23925 47ca794060750b634ab3c34f1aeeff5a 185 Pfam PF00583 Acetyltransferase (GNAT) family 56 156 7.3E-23 T 14-10-2018 IPR000182 GNAT domain C2I25_23925 47ca794060750b634ab3c34f1aeeff5a 185 Gene3D G3DSA:3.40.630.30 1 185 1.1E-59 T 14-10-2018 C2I25_23925 47ca794060750b634ab3c34f1aeeff5a 185 SUPERFAMILY SSF55729 1 167 5.15E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 398 417 4.3E-11 T 14-10-2018 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 300 324 4.3E-11 T 14-10-2018 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 4.3E-11 T 14-10-2018 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 4.3E-11 T 14-10-2018 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 4.3E-11 T 14-10-2018 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 Gene3D G3DSA:1.20.1720.10 12 199 2.1E-49 T 14-10-2018 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 Pfam PF07690 Major Facilitator Superfamily 16 407 2.9E-54 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 SUPERFAMILY SSF103473 6 528 8.24E-79 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 510 3.1E-90 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 Gene3D G3DSA:1.20.1250.20 254 427 7.8E-23 T 14-10-2018 C2I25_08185 02181c281c8a048e8c8c1308f99d3d73 537 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 Gene3D G3DSA:1.10.8.540 497 586 1.0E-13 T 14-10-2018 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 Gene3D G3DSA:1.10.490.80 590 687 1.7E-5 T 14-10-2018 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 PIRSF PIRSF005419 4 688 4.8E-182 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 Pfam PF00771 FHIPEP family 20 679 9.9E-199 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 173 190 5.6E-44 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 224 238 5.6E-44 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 26 39 5.6E-44 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 63 82 5.6E-44 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 124 140 5.6E-44 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 161 5.6E-44 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I25_03010 e7e20c8d69f23acdf45e02de270bde30 688 Gene3D G3DSA:3.40.30.60 352 496 4.5E-36 T 14-10-2018 C2I25_00510 330c50e5eeb4125a7dcf46609b17ec41 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 4.2E-64 T 14-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family C2I25_00510 330c50e5eeb4125a7dcf46609b17ec41 144 Pfam PF06491 Disulphide isomerase 8 144 6.7E-61 T 14-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family C2I25_00510 330c50e5eeb4125a7dcf46609b17ec41 144 Gene3D G3DSA:3.40.30.10 25 144 7.5E-52 T 14-10-2018 C2I25_10125 0876f7d72d7fb3ffce51d06e5edf7583 209 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 208 38.744 T 14-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 C2I25_10125 0876f7d72d7fb3ffce51d06e5edf7583 209 SMART SM00881 79 179 1.5E-19 T 14-10-2018 IPR003781 CoA-binding GO:0048037 C2I25_10125 0876f7d72d7fb3ffce51d06e5edf7583 209 SUPERFAMILY SSF46785 7 78 5.9E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_10125 0876f7d72d7fb3ffce51d06e5edf7583 209 Gene3D G3DSA:3.40.50.720 81 208 2.7E-45 T 14-10-2018 C2I25_10125 0876f7d72d7fb3ffce51d06e5edf7583 209 Pfam PF02629 CoA binding domain 82 177 8.0E-31 T 14-10-2018 IPR003781 CoA-binding GO:0048037 C2I25_10125 0876f7d72d7fb3ffce51d06e5edf7583 209 SUPERFAMILY SSF51735 82 206 6.89E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_10125 0876f7d72d7fb3ffce51d06e5edf7583 209 Gene3D G3DSA:1.10.10.10 1 80 4.9E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_10125 0876f7d72d7fb3ffce51d06e5edf7583 209 Pfam PF06971 Putative DNA-binding protein N-terminus 5 53 3.5E-18 T 14-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 C2I25_01730 9641360ac1f484829ae6c4dee98a05ef 218 Gene3D G3DSA:1.20.120.570 12 207 1.4E-37 T 14-10-2018 IPR036785 YkyA-like superfamily C2I25_01730 9641360ac1f484829ae6c4dee98a05ef 218 Pfam PF10368 Putative cell-wall binding lipoprotein 12 212 3.1E-60 T 14-10-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like C2I25_01730 9641360ac1f484829ae6c4dee98a05ef 218 SUPERFAMILY SSF140423 20 209 2.09E-57 T 14-10-2018 IPR036785 YkyA-like superfamily C2I25_16730 be5568548a7e67fa0676f83e4a82340c 149 SUPERFAMILY SSF111126 16 128 3.14E-24 T 14-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily C2I25_16730 be5568548a7e67fa0676f83e4a82340c 149 Pfam PF10702 Protein of unknown function (DUF2507) 18 140 6.1E-49 T 14-10-2018 IPR019642 Protein of unknown function DUF2507 C2I25_16730 be5568548a7e67fa0676f83e4a82340c 149 Gene3D G3DSA:3.30.1380.20 1 147 2.2E-54 T 14-10-2018 C2I25_03430 234808727baea093fbb9526520f35ce0 350 SUPERFAMILY SSF53756 5 347 5.23E-71 T 14-10-2018 C2I25_03430 234808727baea093fbb9526520f35ce0 350 Gene3D G3DSA:3.40.50.2000 13 343 1.2E-66 T 14-10-2018 C2I25_03430 234808727baea093fbb9526520f35ce0 350 Pfam PF00534 Glycosyl transferases group 1 161 327 2.1E-35 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 C2I25_03430 234808727baea093fbb9526520f35ce0 350 Gene3D G3DSA:3.40.50.2000 160 333 1.2E-66 T 14-10-2018 C2I25_21880 7c359ff58c58b1c007a9754aa4db4e06 299 Gene3D G3DSA:2.130.10.10 41 250 5.2E-7 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_21880 7c359ff58c58b1c007a9754aa4db4e06 299 SUPERFAMILY SSF110296 6 120 5.89E-15 T 14-10-2018 C2I25_21880 7c359ff58c58b1c007a9754aa4db4e06 299 SUPERFAMILY SSF82171 51 266 5.89E-5 T 14-10-2018 C2I25_03320 d2df5c5cc64a77b641c1d697f72b1be6 387 Gene3D G3DSA:1.20.1530.20 2 386 7.8E-107 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily C2I25_03320 d2df5c5cc64a77b641c1d697f72b1be6 387 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 13 281 2.6E-78 T 14-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 C2I25_03320 d2df5c5cc64a77b641c1d697f72b1be6 387 Pfam PF00999 Sodium/hydrogen exchanger family 10 373 4.4E-76 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 SUPERFAMILY SSF53244 310 449 8.47E-44 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 377 2.5E-10 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 449 35.847 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 SUPERFAMILY SSF51984 10 100 1.1E-17 T 14-10-2018 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 SUPERFAMILY SSF53623 103 308 3.51E-49 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 Gene3D G3DSA:3.40.50.720 10 95 2.9E-28 T 14-10-2018 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 Gene3D G3DSA:3.40.1190.10 102 308 8.7E-63 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 447 7.7E-138 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 Gene3D G3DSA:3.90.190.20 315 448 2.2E-43 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_19935 ce031025b4dc3af1ef69906e9f7426fe 450 Pfam PF08245 Mur ligase middle domain 117 290 4.2E-31 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 SUPERFAMILY SSF47384 237 317 1.94E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 Gene3D G3DSA:1.20.1480.50 143 236 2.0E-11 T 14-10-2018 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 468 3.1E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 SMART SM00304 177 229 1.7E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 SMART SM00387 362 475 1.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 Gene3D G3DSA:1.10.287.130 244 318 3.7E-16 T 14-10-2018 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 SUPERFAMILY SSF158472 177 226 1.01E-9 T 14-10-2018 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 429 2.2E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 2.2E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 2.2E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 Gene3D G3DSA:3.30.565.10 322 482 2.7E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 SMART SM00388 251 317 3.8E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 Pfam PF00672 HAMP domain 177 226 7.3E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 316 5.1E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_25970 199c79ee76161dbba49e435e53a26bbe 483 SUPERFAMILY SSF55874 307 474 1.83E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 SUPERFAMILY SSF52777 188 417 4.45E-87 T 14-10-2018 C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 Gene3D G3DSA:3.30.559.10 187 418 6.2E-92 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 Pfam PF00364 Biotin-requiring enzyme 3 75 5.1E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 Gene3D G3DSA:4.10.320.10 125 163 5.2E-15 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 Gene3D G3DSA:2.40.50.100 1 104 8.8E-26 T 14-10-2018 C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 2 418 4.6E-173 T 14-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 187 417 2.3E-80 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 SUPERFAMILY SSF51230 1 94 4.95E-25 T 14-10-2018 IPR011053 Single hybrid motif C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 Pfam PF02817 e3 binding domain 125 159 5.0E-12 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 C2I25_05120 471e46c0d0e7b9320c2f591cc71a2caa 419 SUPERFAMILY SSF47005 119 162 9.02E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 Gene3D G3DSA:3.40.50.620 14 615 6.3E-252 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 623 7.0E-191 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 Pfam PF08264 Anticodon-binding domain of tRNA 675 817 1.7E-30 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 SUPERFAMILY SSF52374 12 637 1.19E-136 T 14-10-2018 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1026 13.918 T 14-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 SUPERFAMILY SSF47323 645 878 9.35E-50 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 Gene3D G3DSA:3.90.740.10 196 388 6.3E-252 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 3.0E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 382 397 3.0E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 558 3.0E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 220 243 3.0E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 509 522 3.0E-30 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 Gene3D G3DSA:1.10.730.10 631 811 1.5E-50 T 14-10-2018 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 SUPERFAMILY SSF47323 946 1014 8.5E-6 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 SUPERFAMILY SSF50677 200 384 1.15E-51 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I25_00485 83187622b5487a8623db56ad4f3599cb 1033 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 830 9.8E-292 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I25_00305 b65d176f830201ca5d39f98b543eb9ab 404 Pfam PF05975 Bacterial ABC transporter protein EcsB 4 388 2.8E-64 T 14-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 C2I25_10275 e2b878ca60009a80e47ec35dd312a33e 119 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 116 6.8E-31 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I25_10275 e2b878ca60009a80e47ec35dd312a33e 119 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 118 2.3E-37 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I25_10275 e2b878ca60009a80e47ec35dd312a33e 119 Gene3D G3DSA:3.90.470.20 1 119 1.4E-39 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_10275 e2b878ca60009a80e47ec35dd312a33e 119 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 11 116 3.0E-54 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I25_10275 e2b878ca60009a80e47ec35dd312a33e 119 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 110 1.5E-19 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_10275 e2b878ca60009a80e47ec35dd312a33e 119 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 25.146 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I25_10275 e2b878ca60009a80e47ec35dd312a33e 119 SUPERFAMILY SSF56214 1 115 2.49E-34 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_13455 93bcbf956b112933ab8c32ec4b577a3f 317 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 316 5.5E-124 T 14-10-2018 IPR010119 Gluconeogenesis factor C2I25_13455 93bcbf956b112933ab8c32ec4b577a3f 317 Hamap MF_00973 Gluconeogenesis factor. 5 312 33.992 T 14-10-2018 IPR010119 Gluconeogenesis factor C2I25_13455 93bcbf956b112933ab8c32ec4b577a3f 317 Pfam PF01933 Uncharacterised protein family UPF0052 9 292 4.9E-104 T 14-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 C2I25_13455 93bcbf956b112933ab8c32ec4b577a3f 317 Gene3D G3DSA:3.40.50.12300 3 316 8.8E-129 T 14-10-2018 IPR038136 Gluconeogenesis factor superfamily C2I25_13455 93bcbf956b112933ab8c32ec4b577a3f 317 SUPERFAMILY SSF142338 6 314 1.7E-106 T 14-10-2018 C2I25_15775 c9ca81a8fba575c12870b876ce48c1cb 357 SUPERFAMILY SSF53187 4 351 1.86E-70 T 14-10-2018 C2I25_15775 c9ca81a8fba575c12870b876ce48c1cb 357 PIRSF PIRSF001123 2 356 3.8E-153 T 14-10-2018 IPR008007 Peptidase M42 C2I25_15775 c9ca81a8fba575c12870b876ce48c1cb 357 Gene3D G3DSA:3.40.630.10 11 340 1.2E-118 T 14-10-2018 C2I25_15775 c9ca81a8fba575c12870b876ce48c1cb 357 SUPERFAMILY SSF101821 71 180 5.49E-31 T 14-10-2018 C2I25_15775 c9ca81a8fba575c12870b876ce48c1cb 357 Gene3D G3DSA:2.40.30.40 75 162 1.2E-118 T 14-10-2018 IPR023367 Peptidase M42, domain 2 C2I25_15775 c9ca81a8fba575c12870b876ce48c1cb 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 4.4E-112 T 14-10-2018 IPR008007 Peptidase M42 C2I25_07310 4058e52e055ef7b91974c43aa3790d4a 189 Pfam PF05067 Manganese containing catalase 1 184 6.2E-76 T 14-10-2018 IPR007760 Manganese catalase C2I25_07310 4058e52e055ef7b91974c43aa3790d4a 189 Gene3D G3DSA:1.20.1260.10 1 184 4.6E-65 T 14-10-2018 IPR012347 Ferritin-like C2I25_07310 4058e52e055ef7b91974c43aa3790d4a 189 SUPERFAMILY SSF47240 1 187 3.78E-69 T 14-10-2018 IPR009078 Ferritin-like superfamily C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 5.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 5.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 5.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 5.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 5.0E-36 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:3.40.50.140 1 134 6.1E-54 T 14-10-2018 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 SUPERFAMILY SSF57783 576 613 3.57E-13 T 14-10-2018 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 643 56.314 T 14-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:1.10.460.10 135 550 2.4E-168 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 SUPERFAMILY SSF56712 4 589 1.96E-202 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 2.1E-265 T 14-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 SMART SM00493 3 103 7.7E-34 T 14-10-2018 IPR006171 TOPRIM domain C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:1.10.290.10 250 385 2.4E-168 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:3.30.65.10 559 617 8.3E-14 T 14-10-2018 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 SMART SM00436 104 192 1.6E-52 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 SMART SM00437 242 510 1.9E-123 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01131 DNA topoisomerase 128 547 1.5E-136 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01751 Toprim domain 5 113 4.4E-30 T 14-10-2018 IPR006171 TOPRIM domain C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:2.70.20.10 184 457 2.4E-168 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 686 0.023 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 576 612 9.8E-15 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 C2I25_20345 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 617 656 8.5E-12 T 14-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 1.2E-39 T 14-10-2018 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 1.2E-39 T 14-10-2018 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 1.2E-39 T 14-10-2018 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 458 480 1.2E-39 T 14-10-2018 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 1.2E-39 T 14-10-2018 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 Pfam PF13192 Thioredoxin domain 125 193 2.4E-7 T 14-10-2018 IPR012336 Thioredoxin-like fold C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 SUPERFAMILY SSF52833 2 100 1.83E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 SUPERFAMILY SSF51905 194 504 2.78E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 468 486 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 5.9E-65 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 483 2.9E-45 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 Gene3D G3DSA:3.50.50.60 209 498 5.0E-106 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 SUPERFAMILY SSF52833 104 194 2.96E-21 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 PIRSF PIRSF000238 2 508 9.9E-259 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 Gene3D G3DSA:3.40.30.80 2 198 7.4E-61 T 14-10-2018 C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 Gene3D G3DSA:3.50.50.60 319 441 5.0E-106 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_09640 ba35c76cbb0e2c4ac38586d580ceaa7d 508 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 508 1.9E-242 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 C2I25_09450 506de531c568a896ba232e89a9136f17 545 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 2 545 0.0 T 14-10-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199 C2I25_09450 506de531c568a896ba232e89a9136f17 545 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 482 499 - T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_09450 506de531c568a896ba232e89a9136f17 545 Gene3D G3DSA:3.30.1360.60 466 545 4.5E-25 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_09450 506de531c568a896ba232e89a9136f17 545 SUPERFAMILY SSF55604 469 544 2.09E-19 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_09450 506de531c568a896ba232e89a9136f17 545 Pfam PF02378 Phosphotransferase system, EIIC 13 377 8.6E-57 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_09450 506de531c568a896ba232e89a9136f17 545 Pfam PF00367 phosphotransferase system, EIIB 472 499 4.0E-14 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_09450 506de531c568a896ba232e89a9136f17 545 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 437 529 1.4E-16 T 14-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I25_15010 4b78641c4dcd4f12ebfb1fb41c3222bf 194 SUPERFAMILY SSF88659 111 176 1.07E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_15010 4b78641c4dcd4f12ebfb1fb41c3222bf 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 177 7.6E-24 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_15010 4b78641c4dcd4f12ebfb1fb41c3222bf 194 SUPERFAMILY SSF88946 3 105 1.81E-17 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_15010 4b78641c4dcd4f12ebfb1fb41c3222bf 194 Pfam PF04542 Sigma-70 region 2 31 83 8.0E-6 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_15010 4b78641c4dcd4f12ebfb1fb41c3222bf 194 Pfam PF04545 Sigma-70, region 4 128 176 1.0E-15 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_15010 4b78641c4dcd4f12ebfb1fb41c3222bf 194 Gene3D G3DSA:1.10.1740.10 3 114 3.3E-14 T 14-10-2018 C2I25_15010 4b78641c4dcd4f12ebfb1fb41c3222bf 194 Gene3D G3DSA:1.10.10.10 115 179 4.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_11575 6ac9c80438a2a9cf52e6f6d4573775e9 295 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 10 295 1.0E-156 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11575 6ac9c80438a2a9cf52e6f6d4573775e9 295 PIRSF PIRSF029271 1 295 1.5E-154 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11575 6ac9c80438a2a9cf52e6f6d4573775e9 295 ProSitePatterns PS01235 PdxS/SNZ family signature. 206 224 - T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11575 6ac9c80438a2a9cf52e6f6d4573775e9 295 SUPERFAMILY SSF51366 19 267 2.21E-69 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I25_11575 6ac9c80438a2a9cf52e6f6d4573775e9 295 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 5 295 54.923 T 14-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11575 6ac9c80438a2a9cf52e6f6d4573775e9 295 Pfam PF01680 SOR/SNZ family 8 213 2.7E-106 T 14-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I25_11575 6ac9c80438a2a9cf52e6f6d4573775e9 295 Gene3D G3DSA:3.20.20.70 2 295 1.5E-147 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_19540 e41b9cb372388571a717ecb7aef189bb 162 Pfam PF13158 Protein of unknown function (DUF3993) 9 124 1.3E-47 T 14-10-2018 IPR025056 Protein of unknown function DUF3993 C2I25_01775 da3a319217df7f62c0922ec50c97f982 352 SUPERFAMILY SSF53686 6 349 9.95E-106 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_01775 da3a319217df7f62c0922ec50c97f982 352 Gene3D G3DSA:3.40.50.1100 12 322 5.5E-122 T 14-10-2018 C2I25_01775 da3a319217df7f62c0922ec50c97f982 352 Gene3D G3DSA:3.40.50.1100 58 154 5.5E-122 T 14-10-2018 C2I25_01775 da3a319217df7f62c0922ec50c97f982 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 C2I25_01775 da3a319217df7f62c0922ec50c97f982 352 PIRSF PIRSF038945 1 347 1.2E-155 T 14-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 C2I25_01775 da3a319217df7f62c0922ec50c97f982 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 1.3E-79 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_01775 da3a319217df7f62c0922ec50c97f982 352 TIGRFAM TIGR00260 thrC: threonine synthase 8 322 1.8E-100 T 14-10-2018 IPR004450 Threonine synthase-like C2I25_17190 03012ac1048f448769603602fd030141 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 84 7.1E-30 T 14-10-2018 IPR003849 Preprotein translocase YajC C2I25_17190 03012ac1048f448769603602fd030141 86 SMART SM01323 3 84 7.0E-41 T 14-10-2018 IPR003849 Preprotein translocase YajC C2I25_17190 03012ac1048f448769603602fd030141 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 5 25 7.0E-15 T 14-10-2018 IPR003849 Preprotein translocase YajC C2I25_17190 03012ac1048f448769603602fd030141 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 43 61 7.0E-15 T 14-10-2018 IPR003849 Preprotein translocase YajC C2I25_17190 03012ac1048f448769603602fd030141 86 Pfam PF02699 Preprotein translocase subunit 7 81 9.1E-30 T 14-10-2018 IPR003849 Preprotein translocase YajC C2I25_14635 487b5cc897946c58e0b0965bcf406b6a 396 Pfam PF00155 Aminotransferase class I and II 30 378 3.2E-71 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_14635 487b5cc897946c58e0b0965bcf406b6a 396 Gene3D G3DSA:3.90.1150.10 25 379 3.1E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_14635 487b5cc897946c58e0b0965bcf406b6a 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 C2I25_14635 487b5cc897946c58e0b0965bcf406b6a 396 Gene3D G3DSA:3.40.640.10 61 282 3.1E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_14635 487b5cc897946c58e0b0965bcf406b6a 396 SUPERFAMILY SSF53383 7 385 2.55E-118 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_04570 4d0fdb155fca348888af3f62e1a658ba 79 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 5 77 1.4E-35 T 14-10-2018 IPR003230 D-alanyl carrier protein GO:0019350|GO:0036370 C2I25_04570 4d0fdb155fca348888af3f62e1a658ba 79 Hamap MF_00565 D-alanyl carrier protein [dltC]. 1 79 45.497 T 14-10-2018 IPR003230 D-alanyl carrier protein GO:0019350|GO:0036370 C2I25_04570 4d0fdb155fca348888af3f62e1a658ba 79 SUPERFAMILY SSF47336 2 77 2.36E-13 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_04570 4d0fdb155fca348888af3f62e1a658ba 79 Pfam PF00550 Phosphopantetheine attachment site 6 71 9.6E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_04570 4d0fdb155fca348888af3f62e1a658ba 79 Gene3D G3DSA:1.10.1200.10 2 79 1.5E-21 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02280 90eb263f845a7d52dc120843238a481c 386 Gene3D G3DSA:1.20.1170.10 45 386 1.2E-128 T 14-10-2018 C2I25_02280 90eb263f845a7d52dc120843238a481c 386 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 42 215 2.0E-55 T 14-10-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 C2I25_02280 90eb263f845a7d52dc120843238a481c 386 SUPERFAMILY SSF58100 39 385 9.68E-71 T 14-10-2018 C2I25_10140 68b5a84f058c084d09b1eb7ce94c0f92 145 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 11 141 2.5E-45 T 14-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 C2I25_10140 68b5a84f058c084d09b1eb7ce94c0f92 145 Pfam PF00583 Acetyltransferase (GNAT) family 14 121 1.1E-20 T 14-10-2018 IPR000182 GNAT domain C2I25_10140 68b5a84f058c084d09b1eb7ce94c0f92 145 Gene3D G3DSA:3.40.630.30 2 145 4.6E-45 T 14-10-2018 C2I25_10140 68b5a84f058c084d09b1eb7ce94c0f92 145 SUPERFAMILY SSF55729 1 135 5.15E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26205 7b86925e176d14b56c55fb999a499b97 304 Pfam PF00892 EamA-like transporter family 16 142 4.9E-29 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_26205 7b86925e176d14b56c55fb999a499b97 304 Pfam PF00892 EamA-like transporter family 152 284 1.4E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_26205 7b86925e176d14b56c55fb999a499b97 304 SUPERFAMILY SSF103481 43 144 1.7E-18 T 14-10-2018 C2I25_26205 7b86925e176d14b56c55fb999a499b97 304 SUPERFAMILY SSF103481 188 287 1.31E-12 T 14-10-2018 C2I25_15735 1ec1149792239192354f4999976b1421 468 Gene3D G3DSA:3.40.630.10 16 466 1.1E-173 T 14-10-2018 C2I25_15735 1ec1149792239192354f4999976b1421 468 Gene3D G3DSA:3.30.70.360 206 293 1.1E-173 T 14-10-2018 C2I25_15735 1ec1149792239192354f4999976b1421 468 Pfam PF01546 Peptidase family M20/M25/M40 87 464 2.1E-34 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_15735 1ec1149792239192354f4999976b1421 468 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 14 463 1.7E-173 T 14-10-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 C2I25_15735 1ec1149792239192354f4999976b1421 468 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 117 156 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 C2I25_15735 1ec1149792239192354f4999976b1421 468 Gene3D G3DSA:3.30.70.360 187 382 1.1E-173 T 14-10-2018 C2I25_15735 1ec1149792239192354f4999976b1421 468 SUPERFAMILY SSF53187 5 467 1.63E-63 T 14-10-2018 C2I25_15735 1ec1149792239192354f4999976b1421 468 SUPERFAMILY SSF55031 187 377 2.21E-54 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_23040 c34fb4d2a9898d1a15d289e66cc857da 251 Pfam PF13489 Methyltransferase domain 41 148 8.5E-18 T 14-10-2018 C2I25_23040 c34fb4d2a9898d1a15d289e66cc857da 251 Gene3D G3DSA:3.40.50.150 39 251 3.6E-46 T 14-10-2018 C2I25_23040 c34fb4d2a9898d1a15d289e66cc857da 251 SUPERFAMILY SSF53335 13 249 8.89E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_24370 3ac3630d1cf119c4483a97385a1460e9 156 Pfam PF00583 Acetyltransferase (GNAT) family 22 124 5.0E-17 T 14-10-2018 IPR000182 GNAT domain C2I25_24370 3ac3630d1cf119c4483a97385a1460e9 156 PIRSF PIRSF037663 1 156 5.5E-75 T 14-10-2018 IPR017255 Acetyltransferase, GNAT, predicted C2I25_24370 3ac3630d1cf119c4483a97385a1460e9 156 Gene3D G3DSA:3.40.630.30 1 156 6.4E-42 T 14-10-2018 C2I25_24370 3ac3630d1cf119c4483a97385a1460e9 156 SUPERFAMILY SSF55729 1 154 4.58E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_23855 68065ae03668c90820ff3a0bf91b0153 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 6.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_23855 68065ae03668c90820ff3a0bf91b0153 198 SUPERFAMILY SSF46689 3 70 9.48E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_23855 68065ae03668c90820ff3a0bf91b0153 198 Gene3D G3DSA:1.10.357.10 73 195 9.3E-15 T 14-10-2018 C2I25_23855 68065ae03668c90820ff3a0bf91b0153 198 Gene3D G3DSA:1.10.10.60 2 68 2.2E-24 T 14-10-2018 C2I25_23855 68065ae03668c90820ff3a0bf91b0153 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 7.5E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_23855 68065ae03668c90820ff3a0bf91b0153 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 7.5E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_23855 68065ae03668c90820ff3a0bf91b0153 198 SUPERFAMILY SSF48498 83 194 7.87E-17 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_19115 013b0584cfc86aaefbf1835caa78ed4b 138 Pfam PF13782 Stage V sporulation protein AB 26 134 3.6E-35 T 14-10-2018 IPR020144 Stage V sporulation protein AB C2I25_19115 013b0584cfc86aaefbf1835caa78ed4b 138 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 1 138 7.0E-63 T 14-10-2018 IPR020144 Stage V sporulation protein AB C2I25_28210 03add432c636914d061494de5d065ecc 385 Pfam PF00149 Calcineurin-like phosphoesterase 1 182 6.1E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_28210 03add432c636914d061494de5d065ecc 385 SUPERFAMILY SSF56300 1 318 9.12E-53 T 14-10-2018 C2I25_28210 03add432c636914d061494de5d065ecc 385 Gene3D G3DSA:3.60.21.10 1 269 9.7E-75 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_28210 03add432c636914d061494de5d065ecc 385 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 249 6.2E-46 T 14-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 C2I25_28210 03add432c636914d061494de5d065ecc 385 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 272 357 4.2E-9 T 14-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain C2I25_21245 5c852ebcb8427f2cde2525bf6a0d2676 158 SMART SM01058 6 116 1.7E-30 T 14-10-2018 IPR003711 CarD-like/TRCF domain C2I25_21245 5c852ebcb8427f2cde2525bf6a0d2676 158 Gene3D G3DSA:2.30.30.840 2 66 3.4E-25 T 14-10-2018 C2I25_21245 5c852ebcb8427f2cde2525bf6a0d2676 158 Gene3D G3DSA:1.20.58.1290 67 158 2.3E-27 T 14-10-2018 C2I25_21245 5c852ebcb8427f2cde2525bf6a0d2676 158 Pfam PF02559 CarD-like/TRCF domain 7 115 1.8E-17 T 14-10-2018 IPR003711 CarD-like/TRCF domain C2I25_21245 5c852ebcb8427f2cde2525bf6a0d2676 158 SUPERFAMILY SSF141259 7 63 2.75E-12 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 SUPERFAMILY SSF52540 316 508 7.05E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 SMART SM00382 349 514 1.1E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 SMART SM00382 28 236 1.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 Gene3D G3DSA:3.40.50.300 3 285 3.0E-63 T 14-10-2018 C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 Gene3D G3DSA:3.40.50.300 288 516 7.5E-43 T 14-10-2018 C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 Pfam PF12848 ABC transporter 230 315 6.8E-21 T 14-10-2018 IPR032781 ABC-transporter extension domain C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 Pfam PF00005 ABC transporter 20 191 1.6E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 SUPERFAMILY SSF52540 4 232 1.62E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12025 7f265dca9d7b3ce6abf8aee2c8de5966 517 Pfam PF00005 ABC transporter 342 468 5.2E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_19825 f12eb022d06d6c0285123df5e9ff96b5 190 PIRSF PIRSF000709 2 79 0.0012 T 14-10-2018 C2I25_19825 f12eb022d06d6c0285123df5e9ff96b5 190 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 184 3.1E-44 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_19825 f12eb022d06d6c0285123df5e9ff96b5 190 SUPERFAMILY SSF53254 1 188 2.08E-47 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_19825 f12eb022d06d6c0285123df5e9ff96b5 190 SMART SM00855 3 147 1.0E-18 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_19825 f12eb022d06d6c0285123df5e9ff96b5 190 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 C2I25_19825 f12eb022d06d6c0285123df5e9ff96b5 190 Gene3D G3DSA:3.40.50.1240 1 190 1.4E-47 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 Pfam PF00155 Aminotransferase class I and II 118 465 5.4E-35 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 Gene3D G3DSA:1.10.10.10 1 73 4.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 SUPERFAMILY SSF46785 3 80 4.93E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 SUPERFAMILY SSF53383 103 475 9.14E-95 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 Gene3D G3DSA:3.90.1150.10 109 473 2.0E-111 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 SMART SM00345 13 72 7.4E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 4.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 4.6E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 1.5E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_26210 4a848571a658aafa1b549e524f7a0530 477 Gene3D G3DSA:3.40.640.10 149 369 2.0E-111 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Pfam PF02811 PHP domain 333 691 9.3E-52 T 14-10-2018 IPR004013 PHP domain GO:0003824 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Gene3D G3DSA:2.40.50.140 216 317 4.5E-35 T 14-10-2018 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 SUPERFAMILY SSF53098 417 873 1.25E-105 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 823 1230 1.5E-94 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Gene3D G3DSA:3.30.1900.20 969 1091 9.2E-58 T 14-10-2018 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Gene3D G3DSA:3.20.20.140 552 798 7.8E-59 T 14-10-2018 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 SMART SM00481 332 399 2.1E-26 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Gene3D G3DSA:1.10.150.870 1284 1419 9.6E-52 T 14-10-2018 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Pfam PF00929 Exonuclease 419 573 7.7E-42 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 227 1433 0.0 T 14-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Gene3D G3DSA:1.10.100.20 991 1038 9.2E-58 T 14-10-2018 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Gene3D G3DSA:1.10.150.700 1203 1282 1.3E-13 T 14-10-2018 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Gene3D G3DSA:1.10.150.700 1092 1181 3.7E-36 T 14-10-2018 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Pfam PF14480 DNA polymerase III polC-type N-terminus I 10 80 1.6E-19 T 14-10-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 410 631 1.0E-64 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 SUPERFAMILY SSF50249 236 317 1.09E-9 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Gene3D G3DSA:3.30.420.10 407 551 9.1E-45 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1433 450.448 T 14-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 SUPERFAMILY SSF160975 1372 1412 6.28E-6 T 14-10-2018 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Pfam PF14579 Helix-hairpin-helix motif 1348 1424 2.0E-8 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 SMART SM00479 417 583 2.8E-55 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_20425 9facac7559cd5a11d3014186f49feac0 1433 Pfam PF11490 DNA polymerase III polC-type N-terminus II 96 205 6.3E-23 T 14-10-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_03285 4284a69144b7d56dbe616a1737bcb525 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 173 1.2E-16 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_03285 4284a69144b7d56dbe616a1737bcb525 179 Gene3D G3DSA:1.10.10.10 102 176 1.5E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_03285 4284a69144b7d56dbe616a1737bcb525 179 Gene3D G3DSA:1.10.1740.10 5 91 2.2E-13 T 14-10-2018 C2I25_03285 4284a69144b7d56dbe616a1737bcb525 179 Pfam PF08281 Sigma-70, region 4 119 171 6.5E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_03285 4284a69144b7d56dbe616a1737bcb525 179 SUPERFAMILY SSF88659 119 176 5.05E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_03285 4284a69144b7d56dbe616a1737bcb525 179 SUPERFAMILY SSF88946 5 107 5.49E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_03285 4284a69144b7d56dbe616a1737bcb525 179 Pfam PF04542 Sigma-70 region 2 25 92 5.9E-6 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_25980 a0da5c710d641150a858bd460a9b9246 231 SUPERFAMILY SSF56784 4 223 3.41E-41 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_25980 a0da5c710d641150a858bd460a9b9246 231 Gene3D G3DSA:1.10.150.240 17 97 2.2E-52 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_25980 a0da5c710d641150a858bd460a9b9246 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 195 1.0E-30 T 14-10-2018 C2I25_25980 a0da5c710d641150a858bd460a9b9246 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 111 190 3.6E-17 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_25980 a0da5c710d641150a858bd460a9b9246 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 100 195 8.1E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_25980 a0da5c710d641150a858bd460a9b9246 231 Gene3D G3DSA:3.40.50.1000 6 219 2.2E-52 T 14-10-2018 IPR023214 HAD superfamily C2I25_03550 7aa978dfd0b126686c2ff0b655eb2b72 440 Pfam PF00860 Permease family 7 385 2.7E-114 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I25_03550 7aa978dfd0b126686c2ff0b655eb2b72 440 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 332 352 - T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I25_03550 7aa978dfd0b126686c2ff0b655eb2b72 440 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 6 415 3.7E-138 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I25_03550 7aa978dfd0b126686c2ff0b655eb2b72 440 TIGRFAM TIGR03173 pbuX: xanthine permease 11 417 1.5E-167 T 14-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 C2I25_18515 bb938f946a6ce41edc291bd7c1a41e44 135 Pfam PF06199 Phage tail tube protein 5 131 1.7E-30 T 14-10-2018 IPR011855 Phage major tail protein TP901-1 C2I25_18515 bb938f946a6ce41edc291bd7c1a41e44 135 TIGRFAM TIGR02126 phgtail_TP901_1: phage major tail protein, TP901-1 family 3 128 4.5E-20 T 14-10-2018 IPR011855 Phage major tail protein TP901-1 C2I25_18515 bb938f946a6ce41edc291bd7c1a41e44 135 PRINTS PR01996 Phage major tail protein 1 family signature 108 132 6.0E-5 T 14-10-2018 IPR022344 Gene transfer agent, major tail protein C2I25_18515 bb938f946a6ce41edc291bd7c1a41e44 135 PRINTS PR01996 Phage major tail protein 1 family signature 20 49 6.0E-5 T 14-10-2018 IPR022344 Gene transfer agent, major tail protein C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 Gene3D G3DSA:3.30.565.10 262 415 9.4E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 SUPERFAMILY SSF47384 183 259 1.14E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 SMART SM00387 303 414 1.3E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 303 412 2.6E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 SMART SM00388 191 258 5.0E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 5.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 5.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 354 5.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 368 5.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 Gene3D G3DSA:1.10.287.130 179 260 3.8E-18 T 14-10-2018 C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 SUPERFAMILY SSF55874 248 412 4.19E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08625 572ebbdd4ba03c471803d5e29664238b 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 192 257 4.7E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_09150 17b46af994538afedd75011abf269bc3 467 Pfam PF02954 Bacterial regulatory protein, Fis family 423 463 3.1E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_09150 17b46af994538afedd75011abf269bc3 467 SUPERFAMILY SSF52540 148 385 3.08E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09150 17b46af994538afedd75011abf269bc3 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 446 466 8.1E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_09150 17b46af994538afedd75011abf269bc3 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 446 8.1E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_09150 17b46af994538afedd75011abf269bc3 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I25_09150 17b46af994538afedd75011abf269bc3 467 Gene3D G3DSA:1.10.10.60 386 467 2.4E-16 T 14-10-2018 C2I25_09150 17b46af994538afedd75011abf269bc3 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I25_09150 17b46af994538afedd75011abf269bc3 467 Pfam PF00158 Sigma-54 interaction domain 149 314 1.3E-62 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I25_09150 17b46af994538afedd75011abf269bc3 467 SMART SM00382 169 311 4.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_09150 17b46af994538afedd75011abf269bc3 467 Gene3D G3DSA:1.10.8.60 319 385 1.7E-22 T 14-10-2018 C2I25_09150 17b46af994538afedd75011abf269bc3 467 Gene3D G3DSA:3.40.50.300 136 318 1.0E-59 T 14-10-2018 C2I25_09150 17b46af994538afedd75011abf269bc3 467 Gene3D G3DSA:3.30.450.20 5 125 1.9E-7 T 14-10-2018 C2I25_09150 17b46af994538afedd75011abf269bc3 467 SUPERFAMILY SSF46689 361 465 1.3E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_09150 17b46af994538afedd75011abf269bc3 467 SUPERFAMILY SSF55785 9 121 1.39E-6 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_09150 17b46af994538afedd75011abf269bc3 467 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 SUPERFAMILY SSF51735 13 285 1.3E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 6.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 6.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 6.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 6.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 6.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 6.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 Gene3D G3DSA:3.40.50.720 12 275 4.1E-71 T 14-10-2018 C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 Pfam PF00106 short chain dehydrogenase 14 201 2.9E-49 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 3.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 3.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25690 158e51fab93264fbc72fc2232a356ce9 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.1E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_08070 22f4485ab5e0c8c69a2720113619b17d 426 SUPERFAMILY SSF50685 366 406 2.16E-7 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_08070 22f4485ab5e0c8c69a2720113619b17d 426 Gene3D G3DSA:2.40.40.10 263 404 4.4E-5 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_08070 22f4485ab5e0c8c69a2720113619b17d 426 Pfam PF06725 3D domain 367 426 3.5E-19 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I25_08070 22f4485ab5e0c8c69a2720113619b17d 426 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 45 242 8.0E-4 T 14-10-2018 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 Gene3D G3DSA:3.30.450.40 18 203 2.8E-61 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_25765 e02e1241a0bf008927049b06678feccb 616 Gene3D G3DSA:1.10.8.60 480 553 2.4E-15 T 14-10-2018 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 395 410 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 Gene3D G3DSA:1.10.10.60 557 616 9.9E-12 T 14-10-2018 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 517 526 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I25_25765 e02e1241a0bf008927049b06678feccb 616 Pfam PF02954 Bacterial regulatory protein, Fis family 574 614 7.6E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 SMART SM00382 328 472 2.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_25765 e02e1241a0bf008927049b06678feccb 616 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 332 345 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 SUPERFAMILY SSF52540 308 545 4.0E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25765 e02e1241a0bf008927049b06678feccb 616 Gene3D G3DSA:3.40.50.300 303 479 7.2E-63 T 14-10-2018 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 597 616 1.3E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 580 597 1.3E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 Pfam PF00158 Sigma-54 interaction domain 309 475 2.3E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 SUPERFAMILY SSF46689 572 616 7.89E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_25765 e02e1241a0bf008927049b06678feccb 616 Pfam PF01590 GAF domain 106 201 2.8E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_14360 f7cef017783b77b142fc26773c02064e 102 PIRSF PIRSF010603 1 102 9.1E-48 T 14-10-2018 IPR009190 Protein of unknown function DUF1462 C2I25_14360 f7cef017783b77b142fc26773c02064e 102 Pfam PF07315 Protein of unknown function (DUF1462) 6 99 5.6E-41 T 14-10-2018 IPR009190 Protein of unknown function DUF1462 C2I25_14360 f7cef017783b77b142fc26773c02064e 102 Gene3D G3DSA:3.40.30.30 1 102 2.6E-38 T 14-10-2018 IPR038218 YuzD-like superfamily C2I25_14360 f7cef017783b77b142fc26773c02064e 102 SUPERFAMILY SSF52833 2 101 3.8E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_25010 95c0e04e773812349c3aa9361730c03e 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 2.0E-21 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_25010 95c0e04e773812349c3aa9361730c03e 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 2.4E-25 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_17775 b3284ed905f1ca8e66b4939f3b240e06 117 Pfam PF01219 Prokaryotic diacylglycerol kinase 11 112 2.2E-37 T 14-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 C2I25_17775 b3284ed905f1ca8e66b4939f3b240e06 117 Gene3D G3DSA:1.10.3830.10 1 116 7.4E-41 T 14-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 C2I25_17775 b3284ed905f1ca8e66b4939f3b240e06 117 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 65 76 - T 14-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 C2I25_16750 7d5a53c063bc56e8a40600b55eff6909 148 Gene3D G3DSA:3.10.129.10 7 148 1.1E-34 T 14-10-2018 C2I25_16750 7d5a53c063bc56e8a40600b55eff6909 148 Pfam PF03061 Thioesterase superfamily 33 118 5.1E-15 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I25_16750 7d5a53c063bc56e8a40600b55eff6909 148 SUPERFAMILY SSF54637 15 147 2.59E-34 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_06635 bb4f624574309b42993fbc973bcaa985 41 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 10 33 7.6E-12 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_06635 bb4f624574309b42993fbc973bcaa985 41 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 12 35 4.4E-12 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_08965 a558af6c83f942f5d35b4c222077052f 176 Gene3D G3DSA:2.40.380.10 19 169 1.7E-11 T 14-10-2018 IPR035930 FomD-like superfamily C2I25_08965 a558af6c83f942f5d35b4c222077052f 176 Pfam PF04167 Protein of unknown function (DUF402) 60 124 6.4E-17 T 14-10-2018 IPR007295 Domain of unknown function DUF402 C2I25_08965 a558af6c83f942f5d35b4c222077052f 176 SUPERFAMILY SSF159234 3 171 7.59E-31 T 14-10-2018 IPR035930 FomD-like superfamily C2I25_08965 a558af6c83f942f5d35b4c222077052f 176 PIRSF PIRSF028345 1 176 1.9E-80 T 14-10-2018 IPR016882 Uncharacterised protein family UPF0374 C2I25_08965 a558af6c83f942f5d35b4c222077052f 176 Hamap MF_01568 UPF0374 protein . 1 175 51.707 T 14-10-2018 IPR016882 Uncharacterised protein family UPF0374 C2I25_11075 430952e4987f847c757b58f7d5713081 135 Gene3D G3DSA:1.10.1520.10 1 135 1.7E-52 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 C2I25_11075 430952e4987f847c757b58f7d5713081 135 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 1 127 30.398 T 14-10-2018 IPR008226 Mini-ribonuclease 3 family C2I25_11075 430952e4987f847c757b58f7d5713081 135 SMART SM00535 1 128 0.003 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I25_11075 430952e4987f847c757b58f7d5713081 135 Pfam PF00636 Ribonuclease III domain 11 108 5.4E-15 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I25_11075 430952e4987f847c757b58f7d5713081 135 SUPERFAMILY SSF69065 3 126 5.76E-44 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 C2I25_11075 430952e4987f847c757b58f7d5713081 135 PIRSF PIRSF005520 1 132 8.0E-54 T 14-10-2018 IPR008226 Mini-ribonuclease 3 family C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 SMART SM00490 563 660 8.9E-8 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 SUPERFAMILY SSF52540 187 445 3.27E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 800 24.993 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 SMART SM00487 261 460 5.7E-25 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 TIGRFAM TIGR00595 priA: primosomal protein N' 289 797 3.7E-219 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 SUPERFAMILY SSF52540 529 705 9.31E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 Pfam PF00271 Helicase conserved C-terminal domain 563 659 1.6E-7 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 Gene3D G3DSA:3.40.50.300 252 447 8.4E-77 T 14-10-2018 C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 Pfam PF04851 Type III restriction enzyme, res subunit 264 428 2.0E-16 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 C2I25_20165 a8e3cb77c9a266e18b2ff39caeab6d22 801 Gene3D G3DSA:1.10.8.630 3 115 6.2E-27 T 14-10-2018 C2I25_28475 8959336622d0c22cbf56089772427d35 436 Gene3D G3DSA:3.90.1150.10 15 424 1.0E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_28475 8959336622d0c22cbf56089772427d35 436 SUPERFAMILY SSF53383 9 427 1.99E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_28475 8959336622d0c22cbf56089772427d35 436 Gene3D G3DSA:3.40.640.10 49 324 1.0E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_28475 8959336622d0c22cbf56089772427d35 436 PIRSF PIRSF000521 16 427 4.3E-42 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_28475 8959336622d0c22cbf56089772427d35 436 Pfam PF00202 Aminotransferase class-III 16 422 3.4E-103 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_28475 8959336622d0c22cbf56089772427d35 436 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_15965 f9034e8fae720b8016ee0832bb3bfda4 572 Gene3D G3DSA:3.30.300.30 458 571 6.0E-28 T 14-10-2018 C2I25_15965 f9034e8fae720b8016ee0832bb3bfda4 572 Pfam PF00501 AMP-binding enzyme 55 462 4.9E-91 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_15965 f9034e8fae720b8016ee0832bb3bfda4 572 SUPERFAMILY SSF56801 21 562 3.01E-161 T 14-10-2018 C2I25_15965 f9034e8fae720b8016ee0832bb3bfda4 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 549 4.7E-24 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_15965 f9034e8fae720b8016ee0832bb3bfda4 572 Gene3D G3DSA:3.40.50.12780 17 455 4.3E-121 T 14-10-2018 C2I25_15965 f9034e8fae720b8016ee0832bb3bfda4 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_02580 3cd1b1e541a043f39b6f3bb9e198ddee 327 PIRSF PIRSF001555 1 327 1.8E-161 T 14-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 C2I25_02580 3cd1b1e541a043f39b6f3bb9e198ddee 327 SUPERFAMILY SSF55681 8 320 9.49E-88 T 14-10-2018 C2I25_02580 3cd1b1e541a043f39b6f3bb9e198ddee 327 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 12 318 2.5E-102 T 14-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 C2I25_02580 3cd1b1e541a043f39b6f3bb9e198ddee 327 Pfam PF03590 Aspartate-ammonia ligase 12 237 1.6E-106 T 14-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 C2I25_02580 3cd1b1e541a043f39b6f3bb9e198ddee 327 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 4 323 50.334 T 14-10-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 C2I25_02580 3cd1b1e541a043f39b6f3bb9e198ddee 327 Gene3D G3DSA:3.30.930.10 5 322 4.6E-142 T 14-10-2018 C2I25_16605 9a42fd53a57d35f70bc574f09270c439 254 PIRSF PIRSF030150 7 252 4.3E-104 T 14-10-2018 IPR015986 Sortase B, Firmicutes C2I25_16605 9a42fd53a57d35f70bc574f09270c439 254 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 11 246 1.9E-99 T 14-10-2018 IPR009835 Sortase B family C2I25_16605 9a42fd53a57d35f70bc574f09270c439 254 SUPERFAMILY SSF63817 21 253 7.98E-89 T 14-10-2018 IPR023365 Sortase domain superfamily C2I25_16605 9a42fd53a57d35f70bc574f09270c439 254 Pfam PF04203 Sortase family 85 251 4.4E-23 T 14-10-2018 IPR005754 Sortase family C2I25_16605 9a42fd53a57d35f70bc574f09270c439 254 Gene3D G3DSA:2.40.260.10 33 254 7.7E-82 T 14-10-2018 IPR023365 Sortase domain superfamily C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 194 211 1.6E-58 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 91 106 1.6E-58 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 143 162 1.6E-58 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 271 283 1.6E-58 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 211 230 1.6E-58 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 129 143 1.6E-58 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 173 185 1.6E-58 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 51 65 1.6E-58 T 14-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 Gene3D G3DSA:3.40.50.300 26 223 4.3E-58 T 14-10-2018 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 48 309 1.1E-134 T 14-10-2018 IPR014232 Sporulation stage V, protein K C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 Gene3D G3DSA:1.10.8.60 224 314 4.9E-18 T 14-10-2018 C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 SMART SM00382 88 226 3.8E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 SUPERFAMILY SSF52540 53 300 8.9E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20985 923d8c9bcd3e67db950db9e0dafd07bc 318 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 92 222 1.0E-19 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_28485 51ea768d23294ed0b979513b4298e694 377 SMART SM00387 271 377 6.7E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_28485 51ea768d23294ed0b979513b4298e694 377 Gene3D G3DSA:1.10.490.70 11 163 2.0E-53 T 14-10-2018 IPR038284 Histidine kinase, N-terminal domain superfamily C2I25_28485 51ea768d23294ed0b979513b4298e694 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 325 6.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_28485 51ea768d23294ed0b979513b4298e694 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 339 6.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_28485 51ea768d23294ed0b979513b4298e694 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 6.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_28485 51ea768d23294ed0b979513b4298e694 377 Pfam PF00512 His Kinase A (phospho-acceptor) domain 168 227 2.8E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_28485 51ea768d23294ed0b979513b4298e694 377 SUPERFAMILY SSF47384 156 227 1.67E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_28485 51ea768d23294ed0b979513b4298e694 377 SUPERFAMILY SSF55874 226 374 3.14E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_28485 51ea768d23294ed0b979513b4298e694 377 Gene3D G3DSA:3.30.565.10 231 377 7.7E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_28485 51ea768d23294ed0b979513b4298e694 377 SMART SM00388 167 229 3.3E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_28485 51ea768d23294ed0b979513b4298e694 377 Pfam PF09385 Histidine kinase N terminal 17 144 1.7E-49 T 14-10-2018 IPR018984 Histidine kinase, N-terminal C2I25_28485 51ea768d23294ed0b979513b4298e694 377 Gene3D G3DSA:1.10.287.130 170 225 1.2E-10 T 14-10-2018 C2I25_28485 51ea768d23294ed0b979513b4298e694 377 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 373 1.0E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_18860 65baab9803165b9caf94d9a77d723290 395 SUPERFAMILY SSF53383 5 390 1.25E-112 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_18860 65baab9803165b9caf94d9a77d723290 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 239 248 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 C2I25_18860 65baab9803165b9caf94d9a77d723290 395 Gene3D G3DSA:3.90.1150.10 39 381 1.1E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_18860 65baab9803165b9caf94d9a77d723290 395 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 21 384 1.1E-137 T 14-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 C2I25_18860 65baab9803165b9caf94d9a77d723290 395 Pfam PF00155 Aminotransferase class I and II 42 384 6.9E-67 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_18860 65baab9803165b9caf94d9a77d723290 395 Gene3D G3DSA:3.40.640.10 57 292 1.1E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 Gene3D G3DSA:1.10.287.130 76 156 3.4E-17 T 14-10-2018 C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 203 306 6.6E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 Gene3D G3DSA:3.30.565.10 158 310 6.2E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 SMART SM00387 198 310 3.5E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 SUPERFAMILY SSF47384 73 153 1.61E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 SMART SM00388 85 152 2.0E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 307 2.0E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 288 2.0E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 235 249 2.0E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 263 2.0E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 SUPERFAMILY SSF55874 143 306 3.27E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_16635 13693692be891b8d17d280bc3501ddbd 311 Pfam PF00512 His Kinase A (phospho-acceptor) domain 85 152 8.2E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 105 269 9.5E-20 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 Gene3D G3DSA:3.30.110.30 403 476 1.1E-23 T 14-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 SUPERFAMILY SSF64586 404 476 1.02E-22 T 14-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 476 6.8E-189 T 14-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 Gene3D G3DSA:3.40.50.800 285 400 1.1E-34 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 SUPERFAMILY SSF52954 279 401 7.2E-33 T 14-10-2018 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 Pfam PF03129 Anticodon binding domain 291 381 3.2E-19 T 14-10-2018 IPR004154 Anticodon-binding C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 Gene3D G3DSA:3.30.930.10 3 284 3.3E-108 T 14-10-2018 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 409 476 1.1E-22 T 14-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 SUPERFAMILY SSF55681 13 277 5.5E-81 T 14-10-2018 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 Hamap MF_01571 Proline--tRNA ligase [proS]. 9 476 44.772 T 14-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 4.1E-10 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 108 119 4.1E-10 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 147 158 4.1E-10 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 67 85 4.1E-10 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I25_09320 646832c07fbbd7cf109bbfef5f40e5dd 476 SMART SM00946 409 476 5.7E-31 T 14-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 C2I25_04675 3eaaf7d1e8f8dfcc225f18cb77b96428 192 SUPERFAMILY SSF55729 2 183 2.13E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_04675 3eaaf7d1e8f8dfcc225f18cb77b96428 192 Gene3D G3DSA:3.40.630.30 1 190 1.5E-43 T 14-10-2018 C2I25_04675 3eaaf7d1e8f8dfcc225f18cb77b96428 192 Pfam PF00583 Acetyltransferase (GNAT) family 36 165 1.5E-14 T 14-10-2018 IPR000182 GNAT domain C2I25_11260 81d1e2bf963d95606828f75b3ac47113 307 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 303 6.4E-147 T 14-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 C2I25_11260 81d1e2bf963d95606828f75b3ac47113 307 Gene3D G3DSA:3.40.50.1100 45 143 8.7E-127 T 14-10-2018 C2I25_11260 81d1e2bf963d95606828f75b3ac47113 307 Gene3D G3DSA:3.40.50.1100 6 299 8.7E-127 T 14-10-2018 C2I25_11260 81d1e2bf963d95606828f75b3ac47113 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 291 1.7E-71 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_11260 81d1e2bf963d95606828f75b3ac47113 307 SUPERFAMILY SSF53686 1 304 4.32E-106 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_11260 81d1e2bf963d95606828f75b3ac47113 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 C2I25_11260 81d1e2bf963d95606828f75b3ac47113 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 303 1.2E-137 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 C2I25_27955 308ffbd7fb24d71eb2080a24d759f9cf 302 Pfam PF00892 EamA-like transporter family 152 286 2.7E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_27955 308ffbd7fb24d71eb2080a24d759f9cf 302 Pfam PF00892 EamA-like transporter family 8 139 4.1E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_27955 308ffbd7fb24d71eb2080a24d759f9cf 302 SUPERFAMILY SSF103481 38 143 9.94E-19 T 14-10-2018 C2I25_27955 308ffbd7fb24d71eb2080a24d759f9cf 302 SUPERFAMILY SSF103481 197 289 1.57E-11 T 14-10-2018 C2I25_19100 2cf0022a91c537b26516c610229cfb78 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 9.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_19100 2cf0022a91c537b26516c610229cfb78 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 9.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_19100 2cf0022a91c537b26516c610229cfb78 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 9.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_19100 2cf0022a91c537b26516c610229cfb78 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 85 111 9.7E-25 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_19100 2cf0022a91c537b26516c610229cfb78 508 Pfam PF00209 Sodium:neurotransmitter symporter family 124 482 3.3E-78 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_19100 2cf0022a91c537b26516c610229cfb78 508 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_19100 2cf0022a91c537b26516c610229cfb78 508 SUPERFAMILY SSF161070 4 486 1.7E-143 T 14-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 C2I25_11050 46040fe68869878276491486e8873e3c 59 Gene3D G3DSA:1.20.5.1030 1 57 3.8E-19 T 14-10-2018 IPR038379 SecE superfamily C2I25_11050 46040fe68869878276491486e8873e3c 59 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 4 59 2.4E-22 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 C2I25_11050 46040fe68869878276491486e8873e3c 59 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 6 34 - T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_11050 46040fe68869878276491486e8873e3c 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 56 12.419 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_11050 46040fe68869878276491486e8873e3c 59 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 5 57 5.1E-21 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_08420 8b1c5ff37376c80e7c1b21351892884b 461 Pfam PF00854 POT family 243 428 6.7E-33 T 14-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 C2I25_08420 8b1c5ff37376c80e7c1b21351892884b 461 Pfam PF00854 POT family 94 214 4.6E-27 T 14-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 C2I25_08420 8b1c5ff37376c80e7c1b21351892884b 461 Gene3D G3DSA:1.20.1250.20 10 235 1.6E-66 T 14-10-2018 C2I25_08420 8b1c5ff37376c80e7c1b21351892884b 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 239 460 4.6E-45 T 14-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 C2I25_08420 8b1c5ff37376c80e7c1b21351892884b 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 214 5.7E-53 T 14-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 C2I25_08420 8b1c5ff37376c80e7c1b21351892884b 461 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 156 168 - T 14-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 C2I25_08420 8b1c5ff37376c80e7c1b21351892884b 461 Gene3D G3DSA:1.20.1250.20 236 461 5.5E-56 T 14-10-2018 C2I25_08420 8b1c5ff37376c80e7c1b21351892884b 461 SUPERFAMILY SSF103473 13 455 6.8E-39 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_15455 203a33190559ff9203285d36f4f4bd5c 277 SUPERFAMILY SSF53474 13 264 2.41E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_15455 203a33190559ff9203285d36f4f4bd5c 277 Gene3D G3DSA:3.40.50.1820 3 273 1.5E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_15455 203a33190559ff9203285d36f4f4bd5c 277 Pfam PF12146 Serine aminopeptidase, S33 18 252 5.3E-58 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 C2I25_02705 ec668affb0102f122e889817fe3ac5eb 364 Gene3D G3DSA:1.25.40.10 7 364 5.9E-89 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_02705 ec668affb0102f122e889817fe3ac5eb 364 SUPERFAMILY SSF48452 130 266 8.54E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_02705 ec668affb0102f122e889817fe3ac5eb 364 SMART SM00028 92 125 64.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_02705 ec668affb0102f122e889817fe3ac5eb 364 SMART SM00028 213 246 52.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_02705 ec668affb0102f122e889817fe3ac5eb 364 SMART SM00028 173 206 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_02705 ec668affb0102f122e889817fe3ac5eb 364 SMART SM00028 132 165 260.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_02705 ec668affb0102f122e889817fe3ac5eb 364 Pfam PF13424 Tetratricopeptide repeat 177 236 2.5E-7 T 14-10-2018 C2I25_17890 ec789b25312b7e191fa0834df0f679fa 370 Gene3D G3DSA:3.20.20.20 1 259 2.0E-110 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_17890 ec789b25312b7e191fa0834df0f679fa 370 Gene3D G3DSA:3.30.413.10 261 360 4.3E-35 T 14-10-2018 C2I25_17890 ec789b25312b7e191fa0834df0f679fa 370 PIRSF PIRSF004640 1 365 2.0E-154 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 C2I25_17890 ec789b25312b7e191fa0834df0f679fa 370 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 2.3E-132 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 C2I25_17890 ec789b25312b7e191fa0834df0f679fa 370 SUPERFAMILY SSF51717 15 214 2.28E-15 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_17890 ec789b25312b7e191fa0834df0f679fa 370 Pfam PF04551 GcpE protein 10 351 9.2E-141 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 C2I25_17890 ec789b25312b7e191fa0834df0f679fa 370 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 35.042 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 C2I25_17890 ec789b25312b7e191fa0834df0f679fa 370 SUPERFAMILY SSF56014 263 352 2.78E-14 T 14-10-2018 C2I25_23390 b1a8c1a01286676c9a9f63368ccc2f7b 243 Gene3D G3DSA:3.30.1380.10 47 239 1.2E-63 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_23390 b1a8c1a01286676c9a9f63368ccc2f7b 243 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 78 219 5.1E-45 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 C2I25_23390 b1a8c1a01286676c9a9f63368ccc2f7b 243 SUPERFAMILY SSF55166 76 226 2.88E-31 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_15470 930f1f05c63b6729ce6bd975d1d3bcd4 433 Pfam PF03929 PepSY-associated TM region 12 376 3.4E-57 T 14-10-2018 IPR005625 PepSY-associated TM protein C2I25_13195 e2b02851318955e708e71dc95a57e914 441 SUPERFAMILY SSF51735 3 167 4.47E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_13195 e2b02851318955e708e71dc95a57e914 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 411 3.5E-52 T 14-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 Gene3D G3DSA:3.90.110.10 170 441 1.2E-107 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 8.0E-50 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 8.0E-50 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 8.0E-50 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 8.0E-50 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 8.0E-50 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 8.0E-50 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 8.0E-50 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 140 171 - T 14-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 Gene3D G3DSA:3.40.50.720 2 169 5.4E-73 T 14-10-2018 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 SUPERFAMILY SSF56327 172 438 6.48E-101 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_13195 e2b02851318955e708e71dc95a57e914 441 Pfam PF02056 Family 4 glycosyl hydrolase 5 186 7.8E-72 T 14-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 Pfam PF12833 Helix-turn-helix domain 28 107 1.8E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 SUPERFAMILY SSF46689 7 56 8.96E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 SUPERFAMILY SSF55136 133 300 5.41E-32 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 SUPERFAMILY SSF46689 58 115 1.34E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 Gene3D G3DSA:1.10.10.60 59 115 3.1E-20 T 14-10-2018 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 SMART SM00342 22 105 4.2E-31 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 74 89 8.2E-7 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 89 105 8.2E-7 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 Gene3D G3DSA:3.20.80.10 133 300 1.0E-45 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 Pfam PF14526 Integron-associated effector binding protein 136 297 1.8E-31 T 14-10-2018 IPR029441 Integron-associated effector binding protein C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 59 101 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 SMART SM00871 133 298 4.4E-40 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_05825 d96c04097d531f45001ae8caa2ce2b82 300 Gene3D G3DSA:1.10.10.60 1 58 4.4E-14 T 14-10-2018 C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 SMART SM00116 86 134 0.0038 T 14-10-2018 IPR000644 CBS domain C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 SMART SM00116 153 204 0.41 T 14-10-2018 IPR000644 CBS domain C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 Gene3D G3DSA:3.10.580.10 63 210 3.0E-57 T 14-10-2018 C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 SUPERFAMILY SSF46785 5 79 3.37E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 SUPERFAMILY SSF54631 74 205 8.46E-23 T 14-10-2018 C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 Gene3D G3DSA:1.10.10.10 5 62 8.5E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 PIRSF PIRSF026546 4 210 1.1E-101 T 14-10-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 Pfam PF08279 HTH domain 9 61 5.7E-12 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 Pfam PF00571 CBS domain 82 134 1.2E-5 T 14-10-2018 IPR000644 CBS domain C2I25_17800 fc5b06577451dbbe2ba03569d5ae9dbd 210 Pfam PF00571 CBS domain 147 204 2.4E-5 T 14-10-2018 IPR000644 CBS domain C2I25_09895 e782bb3db07c64eb2f9c2f14a5c0cf3f 195 Pfam PF00551 Formyl transferase 3 182 1.0E-61 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I25_09895 e782bb3db07c64eb2f9c2f14a5c0cf3f 195 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 189 6.5E-73 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 C2I25_09895 e782bb3db07c64eb2f9c2f14a5c0cf3f 195 SUPERFAMILY SSF53328 3 187 7.46E-62 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I25_09895 e782bb3db07c64eb2f9c2f14a5c0cf3f 195 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I25_09895 e782bb3db07c64eb2f9c2f14a5c0cf3f 195 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 32.406 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 C2I25_09895 e782bb3db07c64eb2f9c2f14a5c0cf3f 195 Gene3D G3DSA:3.40.50.170 1 195 2.2E-75 T 14-10-2018 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 SUPERFAMILY SSF55060 156 280 2.72E-33 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 SUPERFAMILY SSF54211 5 146 3.95E-30 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 Gene3D G3DSA:3.30.70.890 151 257 5.4E-81 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 PRINTS PR00958 Homoserine kinase signature 11 26 7.4E-40 T 14-10-2018 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 PRINTS PR00958 Homoserine kinase signature 122 135 7.4E-40 T 14-10-2018 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 PRINTS PR00958 Homoserine kinase signature 160 177 7.4E-40 T 14-10-2018 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 PRINTS PR00958 Homoserine kinase signature 88 103 7.4E-40 T 14-10-2018 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 PRINTS PR00958 Homoserine kinase signature 240 255 7.4E-40 T 14-10-2018 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 Gene3D G3DSA:3.30.230.10 6 150 5.4E-81 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 81 92 - T 14-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 Pfam PF00288 GHMP kinases N terminal domain 75 135 1.3E-13 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 PIRSF PIRSF000676 1 292 2.2E-94 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 Pfam PF08544 GHMP kinases C terminal 196 272 1.3E-12 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 TIGRFAM TIGR00191 thrB: homoserine kinase 4 291 9.9E-80 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 C2I25_01770 15a61d62fef9dd1c4b1f88117c0e8550 297 Hamap MF_00384 Homoserine kinase [thrB]. 6 290 31.222 T 14-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 C2I25_21755 f38e574f19f4913d3b88d8b388ce903d 154 Gene3D G3DSA:3.90.1170.40 3 147 4.5E-55 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_21755 f38e574f19f4913d3b88d8b388ce903d 154 Pfam PF02391 MoaE protein 9 119 6.3E-38 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_21755 f38e574f19f4913d3b88d8b388ce903d 154 SUPERFAMILY SSF54690 5 138 1.83E-46 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 SUPERFAMILY SSF53067 1 194 7.77E-74 T 14-10-2018 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 197.039 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 PIRSF PIRSF000722 1 396 4.8E-154 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 PRINTS PR00471 Acetate kinase family signature 172 185 3.7E-47 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 PRINTS PR00471 Acetate kinase family signature 202 223 3.7E-47 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 PRINTS PR00471 Acetate kinase family signature 299 312 3.7E-47 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 PRINTS PR00471 Acetate kinase family signature 321 337 3.7E-47 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 PRINTS PR00471 Acetate kinase family signature 4 15 3.7E-47 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 PRINTS PR00471 Acetate kinase family signature 375 387 3.7E-47 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 Gene3D G3DSA:3.30.420.40 2 194 9.7E-77 T 14-10-2018 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 Gene3D G3DSA:3.30.420.40 195 395 1.8E-81 T 14-10-2018 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 Pfam PF00871 Acetokinase family 3 388 8.1E-172 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 SUPERFAMILY SSF53067 156 393 1.02E-93 T 14-10-2018 C2I25_16110 5ddf8b757262b04307d931a08e02dfb1 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 393 1.2E-178 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_01040 21e73ee91888c5878bc7c88518f0c61e 229 Pfam PF02665 Nitrate reductase gamma subunit 3 222 1.6E-87 T 14-10-2018 IPR023234 NarG-like domain C2I25_01040 21e73ee91888c5878bc7c88518f0c61e 229 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 222 5.0E-85 T 14-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 C2I25_01040 21e73ee91888c5878bc7c88518f0c61e 229 SUPERFAMILY SSF103501 1 222 1.83E-69 T 14-10-2018 IPR036197 NarG-like superfamily C2I25_01040 21e73ee91888c5878bc7c88518f0c61e 229 Gene3D G3DSA:1.20.950.20 1 214 8.0E-82 T 14-10-2018 C2I25_20320 46e9cb71361afff831b7b72687b380dc 296 SUPERFAMILY SSF52540 9 192 3.58E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20320 46e9cb71361afff831b7b72687b380dc 296 Gene3D G3DSA:1.10.1580.10 180 272 4.1E-31 T 14-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily C2I25_20320 46e9cb71361afff831b7b72687b380dc 296 Gene3D G3DSA:3.40.50.300 12 179 1.9E-49 T 14-10-2018 C2I25_20320 46e9cb71361afff831b7b72687b380dc 296 PIRSF PIRSF006230 1 283 2.2E-106 T 14-10-2018 IPR016478 GTPase, MTG1 C2I25_20320 46e9cb71361afff831b7b72687b380dc 296 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 9.0E-120 T 14-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis C2I25_20320 46e9cb71361afff831b7b72687b380dc 296 Pfam PF01926 50S ribosome-binding GTPase 123 213 2.9E-17 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_20735 449adde9038257a6393fd12e4cdde578 477 SUPERFAMILY SSF53383 108 475 4.89E-95 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_20735 449adde9038257a6393fd12e4cdde578 477 Gene3D G3DSA:1.10.10.10 5 77 8.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20735 449adde9038257a6393fd12e4cdde578 477 Pfam PF00155 Aminotransferase class I and II 118 460 2.9E-35 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_20735 449adde9038257a6393fd12e4cdde578 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20735 449adde9038257a6393fd12e4cdde578 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20735 449adde9038257a6393fd12e4cdde578 477 SUPERFAMILY SSF46785 6 77 4.17E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_20735 449adde9038257a6393fd12e4cdde578 477 SMART SM00345 17 76 7.0E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20735 449adde9038257a6393fd12e4cdde578 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 8.2E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20735 449adde9038257a6393fd12e4cdde578 477 Gene3D G3DSA:3.40.640.10 151 371 2.3E-106 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_20735 449adde9038257a6393fd12e4cdde578 477 Gene3D G3DSA:3.90.1150.10 114 473 2.3E-106 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 Gene3D G3DSA:3.30.565.10 205 356 2.4E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 SUPERFAMILY SSF47384 120 200 5.89E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 137 201 4.2E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 Gene3D G3DSA:1.20.1480.50 48 131 1.5E-5 T 14-10-2018 C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 SMART SM00388 136 203 1.9E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 314 2.0E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 338 2.0E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 251 346 7.7E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 SUPERFAMILY SSF55874 207 348 4.73E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 SMART SM00387 249 357 1.6E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 SUPERFAMILY SSF158472 83 127 1.57E-6 T 14-10-2018 C2I25_23660 9403b48df01e91e0c5f39f9c2c5720fd 358 Gene3D G3DSA:1.10.287.130 132 202 3.9E-20 T 14-10-2018 C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 Gene3D G3DSA:3.40.50.720 5 228 2.7E-53 T 14-10-2018 C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 SUPERFAMILY SSF51735 7 207 9.82E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 Pfam PF00106 short chain dehydrogenase 8 195 1.3E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_28300 b6af88aafd71961d134949fb43ac5241 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04055 1bde3274893a30623e6e4adfcfa75c8a 386 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 278 358 2.7E-6 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_04055 1bde3274893a30623e6e4adfcfa75c8a 386 Gene3D G3DSA:3.40.710.10 42 277 3.7E-86 T 14-10-2018 C2I25_04055 1bde3274893a30623e6e4adfcfa75c8a 386 SUPERFAMILY SSF56601 13 276 2.39E-65 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_04055 1bde3274893a30623e6e4adfcfa75c8a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 118 135 2.6E-15 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_04055 1bde3274893a30623e6e4adfcfa75c8a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 2.6E-15 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_04055 1bde3274893a30623e6e4adfcfa75c8a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 145 158 2.6E-15 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_04055 1bde3274893a30623e6e4adfcfa75c8a 386 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 39 261 8.2E-67 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_04055 1bde3274893a30623e6e4adfcfa75c8a 386 Gene3D G3DSA:2.30.140.30 278 361 3.0E-9 T 14-10-2018 C2I25_22380 556b8e45ae1f85022060930da5adfc0b 441 PRINTS PR00758 Arsenical pump membrane protein signature 227 252 1.3E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_22380 556b8e45ae1f85022060930da5adfc0b 441 PRINTS PR00758 Arsenical pump membrane protein signature 378 403 1.3E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_22380 556b8e45ae1f85022060930da5adfc0b 441 PRINTS PR00758 Arsenical pump membrane protein signature 286 310 1.3E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_22380 556b8e45ae1f85022060930da5adfc0b 441 PRINTS PR00758 Arsenical pump membrane protein signature 110 134 1.3E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_22380 556b8e45ae1f85022060930da5adfc0b 441 PRINTS PR00758 Arsenical pump membrane protein signature 411 435 1.3E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_22380 556b8e45ae1f85022060930da5adfc0b 441 Pfam PF03600 Citrate transporter 26 382 7.9E-51 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 C2I25_16360 51d1a19cfbe45d77319eb3cf03eb2df2 239 SMART SM00448 3 114 4.6E-48 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_16360 51d1a19cfbe45d77319eb3cf03eb2df2 239 SMART SM00862 156 232 2.8E-29 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_16360 51d1a19cfbe45d77319eb3cf03eb2df2 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 3.6E-30 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_16360 51d1a19cfbe45d77319eb3cf03eb2df2 239 Gene3D G3DSA:3.40.50.2300 1 135 4.4E-40 T 14-10-2018 C2I25_16360 51d1a19cfbe45d77319eb3cf03eb2df2 239 SUPERFAMILY SSF46894 134 233 8.22E-31 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_16360 51d1a19cfbe45d77319eb3cf03eb2df2 239 Pfam PF00072 Response regulator receiver domain 5 114 7.6E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_16360 51d1a19cfbe45d77319eb3cf03eb2df2 239 SUPERFAMILY SSF52172 2 129 5.83E-44 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_16360 51d1a19cfbe45d77319eb3cf03eb2df2 239 Gene3D G3DSA:1.10.10.10 136 238 1.9E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01790 6c52a482162a7088144429cb86377792 202 Gene3D G3DSA:3.90.79.10 1 177 2.0E-31 T 14-10-2018 C2I25_01790 6c52a482162a7088144429cb86377792 202 Pfam PF00293 NUDIX domain 30 144 4.6E-7 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_01790 6c52a482162a7088144429cb86377792 202 SUPERFAMILY SSF55811 3 154 7.76E-22 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:3.40.50.12780 1521 1912 2.2E-136 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:3.40.50.12780 460 863 2.7E-141 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SUPERFAMILY SSF52777 1249 1512 1.78E-63 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1549 1943 7.5E-136 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 488 894 1.2E-141 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:3.30.559.10 1065 1437 1.1E-150 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:3.30.559.30 1247 1490 1.1E-150 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SUPERFAMILY SSF56801 1485 2036 2.09E-163 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SUPERFAMILY SSF52777 191 454 1.33E-54 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:3.30.300.30 1913 2014 1.2E-34 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:3.30.300.30 864 964 2.8E-34 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SUPERFAMILY SSF47336 2016 2090 2.49E-19 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Pfam PF13193 AMP-binding enzyme C-terminal domain 1927 1998 1.6E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Pfam PF13193 AMP-binding enzyme C-terminal domain 878 949 6.2E-9 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2048 2063 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:3.30.559.30 192 443 2.1E-130 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:1.10.1200.10 965 1049 1.3E-25 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SUPERFAMILY SSF47336 969 1076 1.83E-22 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SMART SM00823 Phosphopantetheine attachment site 975 1044 1.4E-4 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SMART SM00823 Phosphopantetheine attachment site 2024 2093 0.1 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Pfam PF00501 AMP-binding enzyme 1528 1919 2.5E-105 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Pfam PF00501 AMP-binding enzyme 467 870 1.4E-106 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SUPERFAMILY SSF52777 10 190 9.56E-42 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1671 1682 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SUPERFAMILY SSF52777 1066 1243 1.01E-46 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Pfam PF00668 Condensation domain 1061 1508 7.0E-119 T 14-10-2018 IPR001242 Condensation domain C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Pfam PF00668 Condensation domain 6 447 6.9E-96 T 14-10-2018 IPR001242 Condensation domain C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 ProSitePatterns PS00455 Putative AMP-binding domain signature. 609 620 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:3.30.559.10 10 378 2.1E-130 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 SUPERFAMILY SSF56801 431 987 7.59E-165 T 14-10-2018 C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Pfam PF00550 Phosphopantetheine attachment site 2026 2089 1.3E-13 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Pfam PF00550 Phosphopantetheine attachment site 977 1040 5.9E-14 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_27410 3ff3988da9b0cdcd8360543466bdc6b2 2156 Gene3D G3DSA:1.10.1200.10 2015 2094 4.4E-25 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_06525 df01156fc752f0f03331f3e7e24115e2 183 Gene3D G3DSA:2.60.40.1240 65 181 2.2E-10 T 14-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily C2I25_06525 df01156fc752f0f03331f3e7e24115e2 183 Pfam PF11611 Domain of unknown function (DUF4352) 78 164 3.5E-7 T 14-10-2018 IPR029051 Domain of unknown function DUF4352 C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 SUPERFAMILY SSF51230 3 92 1.44E-25 T 14-10-2018 IPR011053 Single hybrid motif C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 199 426 1.1E-88 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Pfam PF02817 e3 binding domain 122 156 9.7E-16 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 SUPERFAMILY SSF52777 190 426 7.56E-88 T 14-10-2018 C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Gene3D G3DSA:4.10.320.10 98 164 9.8E-21 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Pfam PF00364 Biotin-requiring enzyme 4 75 1.2E-22 T 14-10-2018 IPR000089 Biotin/lipoyl attachment C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 SUPERFAMILY SSF47005 119 161 8.89E-13 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Gene3D G3DSA:3.30.559.10 184 427 2.6E-90 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_19640 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Gene3D G3DSA:2.40.50.100 2 81 2.1E-25 T 14-10-2018 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:3.30.70.2570 489 563 1.0E-35 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 SUPERFAMILY SSF54980 408 503 1.25E-27 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.8E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 SUPERFAMILY SSF52540 6 239 1.91E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:2.40.30.10 195 294 1.7E-36 T 14-10-2018 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:3.30.70.870 295 376 6.3E-36 T 14-10-2018 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 315.482 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 SUPERFAMILY SSF54980 301 379 1.58E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:3.30.70.3380 377 488 3.9E-44 T 14-10-2018 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Pfam PF03144 Elongation factor Tu domain 2 214 284 1.5E-12 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:3.40.50.300 9 194 5.1E-75 T 14-10-2018 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 2.3E-53 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 SMART SM00838 410 495 1.4E-4 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Pfam PF00679 Elongation factor G C-terminus 408 495 1.9E-25 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 183 1.1E-19 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_17680 c22ab38158e808d5a6ebb8259546cb6c 607 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 3.1E-52 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal C2I25_25205 5fc73cf2d2110858d6079875a8ce8a3e 143 Gene3D G3DSA:3.40.630.30 2 136 8.3E-16 T 14-10-2018 C2I25_25205 5fc73cf2d2110858d6079875a8ce8a3e 143 SUPERFAMILY SSF55729 1 117 1.15E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25205 5fc73cf2d2110858d6079875a8ce8a3e 143 Pfam PF00583 Acetyltransferase (GNAT) family 32 109 3.9E-7 T 14-10-2018 IPR000182 GNAT domain C2I25_26215 fb131bacb7169d2d39eed59a2551d51a 176 Pfam PF14091 Domain of unknown function (DUF4269) 21 167 1.5E-60 T 14-10-2018 IPR025365 Protein of unknown function DUF4269 C2I25_25255 3f5b733e3ce4aff5a8cecf38320c0b90 227 SUPERFAMILY SSF56784 1 216 1.05E-40 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_25255 3f5b733e3ce4aff5a8cecf38320c0b90 227 Gene3D G3DSA:1.10.150.240 16 89 2.1E-31 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_25255 3f5b733e3ce4aff5a8cecf38320c0b90 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 185 1.5E-15 T 14-10-2018 C2I25_25255 3f5b733e3ce4aff5a8cecf38320c0b90 227 Gene3D G3DSA:3.40.50.1000 5 205 2.1E-31 T 14-10-2018 IPR023214 HAD superfamily C2I25_24520 92ddb94651ee1fbaee594597a8902fab 193 Gene3D G3DSA:3.40.50.300 4 193 1.0E-48 T 14-10-2018 C2I25_24520 92ddb94651ee1fbaee594597a8902fab 193 SUPERFAMILY SSF52540 15 192 1.68E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_19030 2a589e60259cb1d181c440de3d3aeefd 316 Gene3D G3DSA:1.20.58.340 239 315 5.4E-30 T 14-10-2018 C2I25_19030 2a589e60259cb1d181c440de3d3aeefd 316 Gene3D G3DSA:3.30.460.20 3 125 3.5E-28 T 14-10-2018 C2I25_19030 2a589e60259cb1d181c440de3d3aeefd 316 Pfam PF01544 CorA-like Mg2+ transporter protein 29 311 9.1E-74 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I25_19030 2a589e60259cb1d181c440de3d3aeefd 316 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 11 315 4.2E-87 T 14-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 C2I25_19030 2a589e60259cb1d181c440de3d3aeefd 316 SUPERFAMILY SSF143865 15 249 4.18E-57 T 14-10-2018 C2I25_19030 2a589e60259cb1d181c440de3d3aeefd 316 SUPERFAMILY SSF144083 251 312 5.23E-21 T 14-10-2018 C2I25_19030 2a589e60259cb1d181c440de3d3aeefd 316 Gene3D G3DSA:1.20.58.340 126 237 1.2E-25 T 14-10-2018 C2I25_16580 682e1ae6b41756df9d17beaba3d07120 152 SUPERFAMILY SSF158911 27 152 3.27E-43 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_16580 682e1ae6b41756df9d17beaba3d07120 152 Pfam PF05031 Iron Transport-associated domain 32 147 9.6E-39 T 14-10-2018 IPR006635 NEAT domain C2I25_16580 682e1ae6b41756df9d17beaba3d07120 152 SMART SM00725 33 152 7.9E-36 T 14-10-2018 IPR006635 NEAT domain C2I25_16580 682e1ae6b41756df9d17beaba3d07120 152 Gene3D G3DSA:2.60.40.1850 23 151 1.2E-46 T 14-10-2018 C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 Pfam PF00005 ABC transporter 18 169 3.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 Pfam PF00005 ABC transporter 269 422 6.7E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 SUPERFAMILY SSF52540 267 480 1.25E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 Gene3D G3DSA:3.40.50.300 251 489 5.2E-46 T 14-10-2018 C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 SMART SM00382 277 471 9.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 SMART SM00382 27 223 1.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 SUPERFAMILY SSF52540 2 219 3.77E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 ProSitePatterns PS00211 ABC transporters family signature. 395 409 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_08165 bc52134aa65b2ccb261024c56a2b5962 494 Gene3D G3DSA:3.40.50.300 1 234 2.5E-58 T 14-10-2018 C2I25_17595 a8543b65b8dfbeaf584598301d30b47a 170 Gene3D G3DSA:3.40.50.1000 15 161 9.5E-24 T 14-10-2018 IPR023214 HAD superfamily C2I25_17595 a8543b65b8dfbeaf584598301d30b47a 170 SUPERFAMILY SSF56784 14 147 5.29E-25 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_17595 a8543b65b8dfbeaf584598301d30b47a 170 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 59 129 1.4E-5 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_17595 a8543b65b8dfbeaf584598301d30b47a 170 Pfam PF13242 HAD-hyrolase-like 90 135 1.8E-11 T 14-10-2018 C2I25_17595 a8543b65b8dfbeaf584598301d30b47a 170 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 2 163 1.1E-57 T 14-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like C2I25_17595 a8543b65b8dfbeaf584598301d30b47a 170 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 35 135 7.1E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_17595 a8543b65b8dfbeaf584598301d30b47a 170 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 27 137 1.1E-23 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 C2I25_17595 a8543b65b8dfbeaf584598301d30b47a 170 Pfam PF08282 haloacid dehalogenase-like hydrolase 29 84 1.3E-4 T 14-10-2018 C2I25_14165 553fa308328b991a038888ddd66b57f1 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_14165 553fa308328b991a038888ddd66b57f1 341 Pfam PF09383 NIL domain 265 337 3.5E-18 T 14-10-2018 IPR018449 NIL domain C2I25_14165 553fa308328b991a038888ddd66b57f1 341 SMART SM00930 263 338 7.1E-26 T 14-10-2018 IPR018449 NIL domain C2I25_14165 553fa308328b991a038888ddd66b57f1 341 SUPERFAMILY SSF55021 249 340 8.81E-21 T 14-10-2018 C2I25_14165 553fa308328b991a038888ddd66b57f1 341 Gene3D G3DSA:3.30.70.260 245 341 1.5E-32 T 14-10-2018 C2I25_14165 553fa308328b991a038888ddd66b57f1 341 SUPERFAMILY SSF52540 1 240 1.69E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_14165 553fa308328b991a038888ddd66b57f1 341 SMART SM00382 30 218 4.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_14165 553fa308328b991a038888ddd66b57f1 341 Gene3D G3DSA:3.40.50.300 1 244 3.9E-75 T 14-10-2018 C2I25_14165 553fa308328b991a038888ddd66b57f1 341 Pfam PF00005 ABC transporter 22 169 2.3E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 Gene3D G3DSA:1.10.8.60 183 257 8.5E-31 T 14-10-2018 C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 332 2.0E-41 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 5.3E-118 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 SUPERFAMILY SSF52540 21 253 1.88E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 3.2E-34 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 SUPERFAMILY SSF46785 257 331 5.71E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 SMART SM00382 52 183 5.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 Gene3D G3DSA:3.40.50.300 21 182 3.1E-41 T 14-10-2018 C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 175.253 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 328 9.9E-149 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 C2I25_17170 14829dc41869d8550f0e6026fd1a03c9 333 Gene3D G3DSA:1.10.10.10 258 333 7.8E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01725 bc51a49fe6f175445d21b5d1a78bd1f2 226 Pfam PF02308 MgtC family 9 138 1.3E-34 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_01725 bc51a49fe6f175445d21b5d1a78bd1f2 226 PRINTS PR01837 MgtC/SapB protein signature 93 117 3.7E-40 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_01725 bc51a49fe6f175445d21b5d1a78bd1f2 226 PRINTS PR01837 MgtC/SapB protein signature 12 31 3.7E-40 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_01725 bc51a49fe6f175445d21b5d1a78bd1f2 226 PRINTS PR01837 MgtC/SapB protein signature 65 87 3.7E-40 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_01725 bc51a49fe6f175445d21b5d1a78bd1f2 226 PRINTS PR01837 MgtC/SapB protein signature 31 49 3.7E-40 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_17845 1ede4bee8478694aa3f920017465beb7 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 31.968 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 C2I25_17845 1ede4bee8478694aa3f920017465beb7 316 Pfam PF02401 LytB protein 4 284 3.7E-81 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 C2I25_17845 1ede4bee8478694aa3f920017465beb7 316 Gene3D G3DSA:3.40.1010.20 7 284 3.4E-95 T 14-10-2018 C2I25_17845 1ede4bee8478694aa3f920017465beb7 316 Gene3D G3DSA:3.40.1010.20 104 197 3.4E-95 T 14-10-2018 C2I25_17845 1ede4bee8478694aa3f920017465beb7 316 Gene3D G3DSA:3.40.50.11270 12 103 3.4E-95 T 14-10-2018 C2I25_17845 1ede4bee8478694aa3f920017465beb7 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 286 9.8E-92 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 C2I25_15055 08fe06fb27e0679693cce094e1368ccf 192 SUPERFAMILY SSF53335 5 168 1.89E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_15055 08fe06fb27e0679693cce094e1368ccf 192 Pfam PF00398 Ribosomal RNA adenine dimethylase 25 141 4.5E-11 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm C2I25_15055 08fe06fb27e0679693cce094e1368ccf 192 Gene3D G3DSA:3.40.50.150 14 185 3.2E-18 T 14-10-2018 C2I25_23480 5547190f62f025f88df09fa3b3df315c 136 Gene3D G3DSA:2.40.350.10 1 128 2.1E-23 T 14-10-2018 IPR023159 SO1590-like superfamily C2I25_23480 5547190f62f025f88df09fa3b3df315c 136 SUPERFAMILY SSF159238 2 131 2.35E-31 T 14-10-2018 IPR023159 SO1590-like superfamily C2I25_23480 5547190f62f025f88df09fa3b3df315c 136 Pfam PF11528 Protein of unknown function (DUF3224) 4 123 5.0E-21 T 14-10-2018 IPR021607 Protein of unknown function DUF3224 C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 Gene3D G3DSA:3.20.20.80 132 419 1.1E-119 T 14-10-2018 C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 SMART SM00636 104 412 7.6E-28 T 14-10-2018 IPR011583 Chitinase II GO:0008061 C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 Gene3D G3DSA:3.10.350.10 2 51 3.7E-11 T 14-10-2018 IPR036779 LysM domain superfamily C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 SMART SM00257 53 97 1.4E-10 T 14-10-2018 IPR018392 LysM domain C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 SMART SM00257 4 48 2.1E-8 T 14-10-2018 IPR018392 LysM domain C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 SUPERFAMILY SSF54106 54 97 3.79E-10 T 14-10-2018 C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 Gene3D G3DSA:3.10.350.10 52 104 1.1E-14 T 14-10-2018 IPR036779 LysM domain superfamily C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 SUPERFAMILY SSF54106 4 48 9.55E-8 T 14-10-2018 C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 Gene3D G3DSA:3.10.50.10 324 383 1.1E-119 T 14-10-2018 IPR029070 Chitinase insertion domain superfamily C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 Pfam PF01476 LysM domain 5 47 5.5E-9 T 14-10-2018 IPR018392 LysM domain C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 Pfam PF01476 LysM domain 54 97 6.2E-10 T 14-10-2018 IPR018392 LysM domain C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 SUPERFAMILY SSF51445 130 427 2.58E-46 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_21520 4772d2e8d59d08abb3a51b109b7d1ddc 430 Pfam PF00704 Glycosyl hydrolases family 18 176 410 8.7E-24 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 C2I25_08305 f3569d47d5747e084cd95d611e88b8cb 486 Pfam PF01235 Sodium:alanine symporter family 50 460 5.9E-158 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_08305 f3569d47d5747e084cd95d611e88b8cb 486 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 448 2.5E-145 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_08305 f3569d47d5747e084cd95d611e88b8cb 486 PRINTS PR00175 Sodium/alanine symporter signature 204 223 8.2E-56 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_08305 f3569d47d5747e084cd95d611e88b8cb 486 PRINTS PR00175 Sodium/alanine symporter signature 417 437 8.2E-56 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_08305 f3569d47d5747e084cd95d611e88b8cb 486 PRINTS PR00175 Sodium/alanine symporter signature 176 194 8.2E-56 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_08305 f3569d47d5747e084cd95d611e88b8cb 486 PRINTS PR00175 Sodium/alanine symporter signature 86 108 8.2E-56 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_08305 f3569d47d5747e084cd95d611e88b8cb 486 PRINTS PR00175 Sodium/alanine symporter signature 354 376 8.2E-56 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_08305 f3569d47d5747e084cd95d611e88b8cb 486 PRINTS PR00175 Sodium/alanine symporter signature 295 313 8.2E-56 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_16865 29a3a20d2307f07b10655ad00d86debd 205 Hamap MF_01405 dITP/XTP pyrophosphatase. 5 200 50.212 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 C2I25_16865 29a3a20d2307f07b10655ad00d86debd 205 SUPERFAMILY SSF52972 3 199 2.35E-72 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I25_16865 29a3a20d2307f07b10655ad00d86debd 205 Gene3D G3DSA:3.90.950.10 2 203 1.0E-79 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I25_16865 29a3a20d2307f07b10655ad00d86debd 205 Pfam PF01725 Ham1 family 7 196 3.3E-60 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 C2I25_16865 29a3a20d2307f07b10655ad00d86debd 205 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 197 6.0E-63 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 C2I25_09505 68788c4d7f8f5f1b9097b033213dd6b7 240 PIRSF PIRSF039085 1 240 9.9E-117 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 C2I25_09505 68788c4d7f8f5f1b9097b033213dd6b7 240 Pfam PF00005 ABC transporter 17 165 1.2E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_09505 68788c4d7f8f5f1b9097b033213dd6b7 240 SMART SM00382 26 213 7.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_09505 68788c4d7f8f5f1b9097b033213dd6b7 240 SUPERFAMILY SSF52540 1 235 4.75E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09505 68788c4d7f8f5f1b9097b033213dd6b7 240 Gene3D G3DSA:3.40.50.300 1 239 9.3E-78 T 14-10-2018 C2I25_09505 68788c4d7f8f5f1b9097b033213dd6b7 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 SUPERFAMILY SSF81330 10 119 6.8E-35 T 14-10-2018 IPR036019 Gated mechanosensitive channel C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 2.3E-11 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 2.3E-11 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.3E-11 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 125 1.3E-49 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 14-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 Gene3D G3DSA:1.10.1200.120 1 126 9.1E-42 T 14-10-2018 IPR036019 Gated mechanosensitive channel C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 124 23.534 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I25_15915 e30c779558344bb338ebdfa9472a2e90 132 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 123 2.7E-46 T 14-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 SUPERFAMILY SSF50249 154 213 4.66E-5 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 Gene3D G3DSA:2.40.50.140 73 149 1.7E-22 T 14-10-2018 C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 Gene3D G3DSA:1.10.10.10 221 282 1.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 SMART SM00316 4 64 1.9 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 SMART SM00316 69 136 36.0 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 SMART SM00316 151 213 4.5 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 Gene3D G3DSA:2.40.50.140 153 219 9.3E-17 T 14-10-2018 C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 PIRSF PIRSF012524 1 284 2.3E-105 T 14-10-2018 IPR014464 Conserved virulence factor B C2I25_05600 64453a25801bc69b820b8ed3e7d6424b 284 Pfam PF13509 S1 domain 5 64 1.1E-20 T 14-10-2018 IPR039566 Conserved virulence factor B, S1 domain C2I25_08750 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 Pfam PF08298 PrkA AAA domain 22 369 6.7E-150 T 14-10-2018 IPR013153 PrkA AAA domain C2I25_08750 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 SMART SM00763 21 371 3.9E-197 T 14-10-2018 IPR013153 PrkA AAA domain C2I25_08750 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 1.9E-93 T 14-10-2018 IPR010650 PrkA C-terminal domain C2I25_08750 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 SUPERFAMILY SSF52540 67 459 2.48E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08750 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 PIRSF PIRSF000549 1 631 7.2E-266 T 14-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 Gene3D G3DSA:1.10.260.30 328 446 1.6E-44 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 SMART SM00962 101 297 4.1E-122 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 Pfam PF02978 Signal peptide binding domain 329 427 8.7E-34 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 SUPERFAMILY SSF47446 329 430 1.8E-37 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 8.8E-191 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 SMART SM00963 2 87 4.9E-34 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 445 35.923 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 SUPERFAMILY SSF52540 43 355 4.48E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.8E-22 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 SMART SM00382 100 302 2.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 Gene3D G3DSA:3.40.50.300 91 286 3.1E-130 T 14-10-2018 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 Gene3D G3DSA:1.20.120.140 6 307 3.1E-130 T 14-10-2018 C2I25_20285 66b9bed48dfb6f7c7615b61153269fa1 449 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 6.8E-80 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_12935 60bdd277539e48d7b4b808c2647f2345 156 SUPERFAMILY SSF88659 92 155 1.5E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_12935 60bdd277539e48d7b4b808c2647f2345 156 SUPERFAMILY SSF88946 8 73 6.8E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_12935 60bdd277539e48d7b4b808c2647f2345 156 Pfam PF04545 Sigma-70, region 4 104 152 1.5E-5 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_12935 60bdd277539e48d7b4b808c2647f2345 156 Gene3D G3DSA:1.20.140.160 70 155 2.3E-7 T 14-10-2018 C2I25_12935 60bdd277539e48d7b4b808c2647f2345 156 Pfam PF04542 Sigma-70 region 2 24 75 2.0E-9 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_12935 60bdd277539e48d7b4b808c2647f2345 156 Gene3D G3DSA:1.10.1740.10 7 69 5.8E-7 T 14-10-2018 C2I25_12935 60bdd277539e48d7b4b808c2647f2345 156 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 152 1.4E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_18885 3dda4f8d99ea7f63dbcdb6aec12ed81c 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 11 149 4.9E-60 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18885 3dda4f8d99ea7f63dbcdb6aec12ed81c 153 Gene3D G3DSA:3.40.50.960 1 153 3.4E-67 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18885 3dda4f8d99ea7f63dbcdb6aec12ed81c 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 7 152 31.399 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18885 3dda4f8d99ea7f63dbcdb6aec12ed81c 153 SUPERFAMILY SSF52121 2 152 1.09E-63 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18885 3dda4f8d99ea7f63dbcdb6aec12ed81c 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 12 147 4.0E-60 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_15385 849565644d85d4bf6b8de9327b757490 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 8.1E-23 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I25_15385 849565644d85d4bf6b8de9327b757490 107 SUPERFAMILY SSF89360 1 104 9.29E-25 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I25_15385 849565644d85d4bf6b8de9327b757490 107 Gene3D G3DSA:2.60.300.12 1 102 2.6E-6 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I25_17675 dd9828a6b202f1c45c14e108290cd4cf 121 Pfam PF12438 Protein of unknown function (DUF3679) 16 70 2.9E-22 T 14-10-2018 IPR020534 Uncharacterised protein family YqxA C2I25_17675 dd9828a6b202f1c45c14e108290cd4cf 121 ProDom PD072942 YQXA ORF79 9 98 1.0E-44 T 14-10-2018 IPR020534 Uncharacterised protein family YqxA C2I25_24935 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 SMART SM00028 37 72 85.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_24935 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 SMART SM00028 74 107 0.12 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_24935 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 SUPERFAMILY SSF48452 7 132 4.17E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_24935 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 Pfam PF12688 Tetratrico peptide repeat 40 155 1.2E-13 T 14-10-2018 C2I25_24935 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 Gene3D G3DSA:1.25.40.10 48 153 1.3E-18 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_22365 be452ff54d20004cdae941782fb804f7 302 Gene3D G3DSA:3.40.50.1980 24 141 8.1E-17 T 14-10-2018 C2I25_22365 be452ff54d20004cdae941782fb804f7 302 SUPERFAMILY SSF53807 40 300 4.32E-48 T 14-10-2018 C2I25_22365 be452ff54d20004cdae941782fb804f7 302 Pfam PF01497 Periplasmic binding protein 51 279 4.1E-31 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_22365 be452ff54d20004cdae941782fb804f7 302 Gene3D G3DSA:3.40.50.1980 142 302 8.7E-38 T 14-10-2018 C2I25_20210 b093b9a45a9c2eadb5b149f3aab3fac6 213 SUPERFAMILY SSF63862 133 211 3.79E-16 T 14-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I25_20210 b093b9a45a9c2eadb5b149f3aab3fac6 213 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 209 7.7E-58 T 14-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I25_20210 b093b9a45a9c2eadb5b149f3aab3fac6 213 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 142 206 2.7E-19 T 14-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I25_20210 b093b9a45a9c2eadb5b149f3aab3fac6 213 SUPERFAMILY SSF63999 3 130 9.29E-33 T 14-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I25_20210 b093b9a45a9c2eadb5b149f3aab3fac6 213 Gene3D G3DSA:3.40.50.10240 1 213 2.9E-73 T 14-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I25_20210 b093b9a45a9c2eadb5b149f3aab3fac6 213 SMART SM00983 141 207 1.3E-25 T 14-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I25_20210 b093b9a45a9c2eadb5b149f3aab3fac6 213 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 19 127 4.1E-20 T 14-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I25_12915 36f75c159626c37db37e5148dbecf6c6 397 Gene3D G3DSA:2.40.30.170 226 319 7.2E-8 T 14-10-2018 C2I25_12915 36f75c159626c37db37e5148dbecf6c6 397 Pfam PF13533 Biotin-lipoyl like 82 119 1.2E-7 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain C2I25_12915 36f75c159626c37db37e5148dbecf6c6 397 Pfam PF13437 HlyD family secretion protein 195 309 2.8E-6 T 14-10-2018 C2I25_12915 36f75c159626c37db37e5148dbecf6c6 397 SUPERFAMILY SSF111369 82 164 9.68E-5 T 14-10-2018 C2I25_12915 36f75c159626c37db37e5148dbecf6c6 397 Gene3D G3DSA:2.40.420.20 320 384 1.1E-12 T 14-10-2018 C2I25_12915 36f75c159626c37db37e5148dbecf6c6 397 Gene3D G3DSA:2.40.50.100 79 219 1.2E-6 T 14-10-2018 C2I25_23990 e59078b5fca3a3dce681020c6c235c25 367 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 367 1.9E-57 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_23990 e59078b5fca3a3dce681020c6c235c25 367 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 196 364 2.1E-25 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_23990 e59078b5fca3a3dce681020c6c235c25 367 Gene3D G3DSA:3.30.300.210 213 367 1.0E-22 T 14-10-2018 IPR038501 Spore germination GerAC superfamily C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 Gene3D G3DSA:1.20.140.10 235 379 6.0E-59 T 14-10-2018 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 PIRSF PIRSF016578 3 377 1.1E-21 T 14-10-2018 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 SUPERFAMILY SSF47203 227 378 9.67E-62 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.5E-28 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 SUPERFAMILY SSF56645 2 242 1.83E-97 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 Gene3D G3DSA:1.10.540.10 1 120 4.0E-48 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 Gene3D G3DSA:2.40.110.10 121 234 2.3E-47 T 14-10-2018 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.2E-44 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 9.6E-54 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I25_12460 63136f3c19deebf286e1699e0cb30fde 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_27935 dcf1188336189f633c3bb7a2bf2ed0bd 463 Gene3D G3DSA:3.90.660.20 40 407 2.2E-113 T 14-10-2018 C2I25_27935 dcf1188336189f633c3bb7a2bf2ed0bd 463 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 1 459 3.4E-82 T 14-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 C2I25_27935 dcf1188336189f633c3bb7a2bf2ed0bd 463 Gene3D G3DSA:3.50.50.60 5 449 2.2E-113 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_27935 dcf1188336189f633c3bb7a2bf2ed0bd 463 SUPERFAMILY SSF51905 2 458 5.67E-41 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_27935 dcf1188336189f633c3bb7a2bf2ed0bd 463 Pfam PF01593 Flavin containing amine oxidoreductase 31 458 2.5E-41 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I25_27935 dcf1188336189f633c3bb7a2bf2ed0bd 463 Gene3D G3DSA:1.10.3110.10 106 199 2.2E-113 T 14-10-2018 C2I25_27935 dcf1188336189f633c3bb7a2bf2ed0bd 463 SUPERFAMILY SSF54373 300 407 1.8E-20 T 14-10-2018 C2I25_20305 33b48eeb2b3dc375a5934b9d174c6d93 244 PIRSF PIRSF000386 1 244 4.7E-107 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I25_20305 33b48eeb2b3dc375a5934b9d174c6d93 244 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 5.5E-104 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I25_20305 33b48eeb2b3dc375a5934b9d174c6d93 244 SUPERFAMILY SSF75217 1 243 4.91E-106 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I25_20305 33b48eeb2b3dc375a5934b9d174c6d93 244 Gene3D G3DSA:1.10.1270.20 166 244 2.4E-35 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I25_20305 33b48eeb2b3dc375a5934b9d174c6d93 244 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 244 116.808 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I25_20305 33b48eeb2b3dc375a5934b9d174c6d93 244 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 1.0E-74 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I25_20305 33b48eeb2b3dc375a5934b9d174c6d93 244 Gene3D G3DSA:3.40.1280.10 1 165 5.4E-71 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I25_01785 27574bd4c8575097c98ddd6cf1a87fec 212 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 16 212 1.2E-80 T 14-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent C2I25_01785 27574bd4c8575097c98ddd6cf1a87fec 212 Gene3D G3DSA:2.30.110.10 29 156 2.6E-24 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I25_01785 27574bd4c8575097c98ddd6cf1a87fec 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 37 131 4.7E-13 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 C2I25_01785 27574bd4c8575097c98ddd6cf1a87fec 212 SUPERFAMILY SSF50475 26 180 5.61E-20 T 14-10-2018 C2I25_00260 ee816acc398dbaa9a00a908b90cadae7 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 30.138 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 C2I25_00260 ee816acc398dbaa9a00a908b90cadae7 211 Gene3D G3DSA:3.40.50.360 1 211 7.6E-67 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_00260 ee816acc398dbaa9a00a908b90cadae7 211 SUPERFAMILY SSF52218 1 211 1.35E-54 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_00260 ee816acc398dbaa9a00a908b90cadae7 211 Pfam PF02525 Flavodoxin-like fold 2 206 3.9E-48 T 14-10-2018 IPR003680 Flavodoxin-like fold C2I25_17355 4c9e5f59e163b9cab8fc532f6c774e56 356 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 13 355 6.0E-98 T 14-10-2018 IPR003770 Endolytic murein transglycosylase C2I25_17355 4c9e5f59e163b9cab8fc532f6c774e56 356 Pfam PF02618 YceG-like family 49 349 8.0E-78 T 14-10-2018 IPR003770 Endolytic murein transglycosylase C2I25_17355 4c9e5f59e163b9cab8fc532f6c774e56 356 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 15 355 32.735 T 14-10-2018 IPR003770 Endolytic murein transglycosylase C2I25_17355 4c9e5f59e163b9cab8fc532f6c774e56 356 Gene3D G3DSA:1.10.8.1150 43 117 1.1E-23 T 14-10-2018 C2I25_02310 5ec018027b84a659f24fe27455870797 431 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 19 429 38.758 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I25_02310 5ec018027b84a659f24fe27455870797 431 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 34 397 9.5E-126 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I25_02310 5ec018027b84a659f24fe27455870797 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 167 188 1.4E-33 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I25_02310 5ec018027b84a659f24fe27455870797 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 217 240 1.4E-33 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I25_02310 5ec018027b84a659f24fe27455870797 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 114 140 1.4E-33 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I25_02310 5ec018027b84a659f24fe27455870797 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 319 338 1.4E-33 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I25_02310 5ec018027b84a659f24fe27455870797 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 142 161 1.4E-33 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I25_02310 5ec018027b84a659f24fe27455870797 431 Pfam PF01566 Natural resistance-associated macrophage protein 55 403 1.5E-118 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I25_11410 814d7fb757e276d12d30b44b4a249667 185 SUPERFAMILY SSF110455 1 114 3.4E-36 T 14-10-2018 C2I25_11410 814d7fb757e276d12d30b44b4a249667 185 Pfam PF13331 Domain of unknown function (DUF4093) 93 175 5.0E-27 T 14-10-2018 IPR025156 Ribonuclease M5, C-terminal domain C2I25_11410 814d7fb757e276d12d30b44b4a249667 185 Pfam PF13662 Toprim domain 4 70 2.4E-7 T 14-10-2018 IPR006171 TOPRIM domain C2I25_11410 814d7fb757e276d12d30b44b4a249667 185 SMART SM00493 4 77 2.6E-7 T 14-10-2018 IPR006171 TOPRIM domain C2I25_11410 814d7fb757e276d12d30b44b4a249667 185 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 173 1.4E-64 T 14-10-2018 IPR004466 Ribonuclease M5 GO:0043822 C2I25_11410 814d7fb757e276d12d30b44b4a249667 185 Hamap MF_01469 Ribonuclease M5 [rnmV]. 3 178 32.948 T 14-10-2018 IPR004466 Ribonuclease M5 GO:0043822 C2I25_11410 814d7fb757e276d12d30b44b4a249667 185 Gene3D G3DSA:3.40.1360.20 1 119 8.1E-26 T 14-10-2018 C2I25_10515 b145713cb545fc29d34693d9d0b59a4a 283 SUPERFAMILY SSF103481 187 278 2.62E-6 T 14-10-2018 C2I25_10515 b145713cb545fc29d34693d9d0b59a4a 283 SUPERFAMILY SSF103481 36 138 2.09E-7 T 14-10-2018 C2I25_10515 b145713cb545fc29d34693d9d0b59a4a 283 Pfam PF06800 Sugar transport protein 4 280 1.2E-99 T 14-10-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 C2I25_04480 5ded4cd33cf3eac38e0f8b5897abe116 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 6.6E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04480 5ded4cd33cf3eac38e0f8b5897abe116 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 76 6.6E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04480 5ded4cd33cf3eac38e0f8b5897abe116 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 44 60 6.6E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04480 5ded4cd33cf3eac38e0f8b5897abe116 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 6.6E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04480 5ded4cd33cf3eac38e0f8b5897abe116 131 Gene3D G3DSA:1.10.10.10 1 131 1.6E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04480 5ded4cd33cf3eac38e0f8b5897abe116 131 SUPERFAMILY SSF46785 4 130 1.37E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_04480 5ded4cd33cf3eac38e0f8b5897abe116 131 Pfam PF01047 MarR family 28 85 7.3E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04480 5ded4cd33cf3eac38e0f8b5897abe116 131 SMART SM00347 21 120 7.6E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_26130 3524eb579d3531a85de6a78ebcf7a279 320 PIRSF PIRSF038896 2 309 3.4E-93 T 14-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 C2I25_26130 3524eb579d3531a85de6a78ebcf7a279 320 SUPERFAMILY SSF56281 55 306 2.49E-37 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_26130 3524eb579d3531a85de6a78ebcf7a279 320 Pfam PF12706 Beta-lactamase superfamily domain 72 267 1.9E-41 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_26130 3524eb579d3531a85de6a78ebcf7a279 320 Gene3D G3DSA:3.60.15.10 43 316 1.4E-80 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_24390 8f1e565a176b6d501bd8a5fcc8a08438 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 82 221 3.2E-5 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_24390 8f1e565a176b6d501bd8a5fcc8a08438 345 SUPERFAMILY SSF51735 1 320 3.56E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_24390 8f1e565a176b6d501bd8a5fcc8a08438 345 Gene3D G3DSA:3.40.50.720 1 265 2.6E-32 T 14-10-2018 C2I25_00245 5a46e4c51dddfe0bc324d3b26e5b78ed 61 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 60 18.949 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 C2I25_00245 5a46e4c51dddfe0bc324d3b26e5b78ed 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.2E-6 T 14-10-2018 C2I25_00245 5a46e4c51dddfe0bc324d3b26e5b78ed 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.2E-6 T 14-10-2018 C2I25_00245 5a46e4c51dddfe0bc324d3b26e5b78ed 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.2E-6 T 14-10-2018 C2I25_00245 5a46e4c51dddfe0bc324d3b26e5b78ed 61 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 7.1E-20 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 C2I25_00245 5a46e4c51dddfe0bc324d3b26e5b78ed 61 Pfam PF02416 mttA/Hcf106 family 5 56 5.5E-22 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 C2I25_21000 d1ba069256a9cf38ac74e970b8121d70 423 Gene3D G3DSA:3.40.640.10 58 271 1.3E-185 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_21000 d1ba069256a9cf38ac74e970b8121d70 423 SUPERFAMILY SSF53383 60 398 1.31E-48 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_21000 d1ba069256a9cf38ac74e970b8121d70 423 Gene3D G3DSA:3.90.1150.60 17 411 1.3E-185 T 14-10-2018 C2I25_21000 d1ba069256a9cf38ac74e970b8121d70 423 Pfam PF06838 Methionine gamma-lyase 14 414 2.4E-210 T 14-10-2018 IPR009651 Putative methionine gamma-lyase C2I25_01200 b3da021194c38d0e3cec04e954a622d8 188 SUPERFAMILY SSF55729 4 176 6.45E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01200 b3da021194c38d0e3cec04e954a622d8 188 Gene3D G3DSA:3.40.630.30 1 186 1.8E-38 T 14-10-2018 C2I25_01200 b3da021194c38d0e3cec04e954a622d8 188 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 4.4E-20 T 14-10-2018 IPR000182 GNAT domain C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 Pfam PF13393 Histidyl-tRNA synthetase 8 323 6.7E-37 T 14-10-2018 C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 SUPERFAMILY SSF52954 338 425 1.19E-18 T 14-10-2018 C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 PIRSF PIRSF001549 1 425 1.4E-129 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 417 3.5E-111 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 Pfam PF03129 Anticodon binding domain 340 425 2.4E-12 T 14-10-2018 IPR004154 Anticodon-binding C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 Gene3D G3DSA:3.40.50.800 337 425 3.1E-21 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 423 24.712 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 SUPERFAMILY SSF55681 5 331 4.98E-71 T 14-10-2018 C2I25_23225 0d2c6b90acbc574657ea7ba0b56947c4 425 Gene3D G3DSA:3.30.930.10 1 336 3.9E-100 T 14-10-2018 C2I25_06195 f6fb715fbad3c84208bfc3163923c078 111 Gene3D G3DSA:1.10.3750.10 1 111 8.1E-35 T 14-10-2018 IPR035945 YhaI-like superfamily C2I25_06195 f6fb715fbad3c84208bfc3163923c078 111 SUPERFAMILY SSF109915 1 110 1.18E-48 T 14-10-2018 IPR035945 YhaI-like superfamily C2I25_06195 f6fb715fbad3c84208bfc3163923c078 111 ProDom PD073069 YHAI 3D-STRUCTURE 11 100 4.0E-45 T 14-10-2018 IPR015058 Protein of unknown function DUF1878 C2I25_06195 f6fb715fbad3c84208bfc3163923c078 111 Pfam PF08963 Protein of unknown function (DUF1878) 2 108 2.4E-43 T 14-10-2018 IPR015058 Protein of unknown function DUF1878 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 615 1.2E-38 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 SUPERFAMILY SSF56601 244 659 2.5E-100 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 SMART SM00060 677 751 7.2E-8 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 Gene3D G3DSA:3.40.710.10 326 653 2.0E-203 T 14-10-2018 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 Gene3D G3DSA:3.90.1310.20 80 536 2.0E-203 T 14-10-2018 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 SUPERFAMILY SSF49265 678 759 7.96E-12 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 Pfam PF00912 Transglycosylase 84 260 2.0E-65 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 Gene3D G3DSA:1.10.3810.10 94 287 2.0E-203 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 Gene3D G3DSA:2.60.40.10 672 762 3.0E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 94 642 2.7E-171 T 14-10-2018 C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 SUPERFAMILY SSF53955 73 285 5.34E-74 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily C2I25_03645 7b7016eb3893ca3a9f78e12aa01046e1 897 Pfam PF00041 Fibronectin type III domain 678 752 2.4E-10 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 165 1.1E-32 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 Pfam PF02464 Competence-damaged protein 258 408 3.7E-50 T 14-10-2018 IPR008136 CinA, C-terminal C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 SMART SM00852 4 170 4.0E-42 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 SUPERFAMILY SSF142433 249 410 6.02E-46 T 14-10-2018 IPR036653 CinA-like, C-terminal C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 PIRSF PIRSF006728 1 412 1.2E-165 T 14-10-2018 IPR008135 Competence-induced protein CinA C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 264 409 1.6E-43 T 14-10-2018 IPR008136 CinA, C-terminal C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 412 166.668 T 14-10-2018 IPR008135 Competence-induced protein CinA C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 Gene3D G3DSA:3.40.980.10 1 169 4.4E-51 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 Pfam PF00994 Probable molybdopterin binding domain 4 169 3.7E-37 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 Gene3D G3DSA:3.90.950.20 252 412 3.0E-49 T 14-10-2018 IPR036653 CinA-like, C-terminal C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 SUPERFAMILY SSF53218 1 205 3.27E-41 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_20610 6ab02600c3a11cb5d39cd0482f5b6424 412 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 410 5.0E-154 T 14-10-2018 IPR008135 Competence-induced protein CinA C2I25_01600 e398802831040341708db02d18f3f498 391 Gene3D G3DSA:1.20.1250.20 1 377 1.6E-58 T 14-10-2018 C2I25_01600 e398802831040341708db02d18f3f498 391 Pfam PF07690 Major Facilitator Superfamily 9 318 2.5E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_01600 e398802831040341708db02d18f3f498 391 SUPERFAMILY SSF103473 2 382 4.32E-67 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_01600 e398802831040341708db02d18f3f498 391 PRINTS PR01035 Tetracycline resistance protein signature 129 151 1.7E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_01600 e398802831040341708db02d18f3f498 391 PRINTS PR01035 Tetracycline resistance protein signature 14 30 1.7E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_01600 e398802831040341708db02d18f3f498 391 PRINTS PR01035 Tetracycline resistance protein signature 324 347 1.7E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_01600 e398802831040341708db02d18f3f498 391 PRINTS PR01035 Tetracycline resistance protein signature 157 177 1.7E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_25405 cfaca39b7906f20ebcfecf6124905009 391 Pfam PF01266 FAD dependent oxidoreductase 5 365 1.2E-67 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I25_25405 cfaca39b7906f20ebcfecf6124905009 391 Gene3D G3DSA:3.50.50.60 6 369 2.2E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25405 cfaca39b7906f20ebcfecf6124905009 391 SUPERFAMILY SSF54373 270 326 1.7E-11 T 14-10-2018 C2I25_25405 cfaca39b7906f20ebcfecf6124905009 391 Gene3D G3DSA:3.30.9.10 85 326 2.2E-88 T 14-10-2018 C2I25_25405 cfaca39b7906f20ebcfecf6124905009 391 SUPERFAMILY SSF51905 3 386 5.61E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25405 cfaca39b7906f20ebcfecf6124905009 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 7.2E-8 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_25405 cfaca39b7906f20ebcfecf6124905009 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 319 325 7.2E-8 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_25405 cfaca39b7906f20ebcfecf6124905009 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 7.2E-8 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 SMART SM00382 103 252 4.8E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 SUPERFAMILY SSF46785 16 61 8.14E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 Gene3D G3DSA:3.40.50.510 535 668 2.2E-37 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 Pfam PF00874 PRD domain 442 528 7.7E-22 T 14-10-2018 IPR011608 PRD domain GO:0006355 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 Pfam PF00874 PRD domain 799 884 3.3E-14 T 14-10-2018 IPR011608 PRD domain GO:0006355 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 Gene3D G3DSA:3.40.50.300 68 255 1.8E-39 T 14-10-2018 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 SUPERFAMILY SSF53062 539 660 5.76E-20 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 175 190 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 Pfam PF03610 PTS system fructose IIA component 541 653 6.4E-8 T 14-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 Gene3D G3DSA:1.10.1790.10 433 530 8.1E-25 T 14-10-2018 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 Gene3D G3DSA:1.10.1790.10 791 887 5.1E-8 T 14-10-2018 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 Pfam PF00158 Sigma-54 interaction domain 83 244 5.2E-45 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 SUPERFAMILY SSF63520 428 528 6.28E-24 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 SUPERFAMILY SSF52540 98 322 9.0E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13215 6b71eae62bb74b5784383dec65df918e 891 SUPERFAMILY SSF63520 792 885 1.1E-15 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I25_08935 773974cbb718005d545eacac3b3880a6 263 Pfam PF06182 ABC-2 family transporter protein 31 258 2.3E-22 T 14-10-2018 IPR010390 Protein of unknown function DUF990 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 SUPERFAMILY SSF55120 61 225 1.53E-39 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 Gene3D G3DSA:3.10.290.10 3 57 6.5E-19 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 SUPERFAMILY SSF55174 4 57 1.68E-12 T 14-10-2018 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 Gene3D G3DSA:3.30.70.1560 129 202 3.4E-54 T 14-10-2018 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 Gene3D G3DSA:3.30.70.580 65 223 3.4E-54 T 14-10-2018 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 Pfam PF00849 RNA pseudouridylate synthase 64 190 3.3E-14 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 SMART SM00363 4 64 3.4E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 221 2.1E-47 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I25_28085 d4083a3be605f2d80ccd7c86dc4022bb 238 Pfam PF01479 S4 domain 5 49 1.5E-11 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10875 573d609e860643eae11d1f68ef6f605f 146 Gene3D G3DSA:3.100.10.10 66 146 1.2E-28 T 14-10-2018 C2I25_10875 573d609e860643eae11d1f68ef6f605f 146 SUPERFAMILY SSF52080 4 144 1.7E-50 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily C2I25_10875 573d609e860643eae11d1f68ef6f605f 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 3.1E-38 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P C2I25_10875 573d609e860643eae11d1f68ef6f605f 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 2.8E-56 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10875 573d609e860643eae11d1f68ef6f605f 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 14-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10875 573d609e860643eae11d1f68ef6f605f 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.824 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 C2I25_03520 d8c7b6a56c0bd718cb6905565b22c64a 90 Pfam PF10752 Protein of unknown function (DUF2533) 1 83 5.0E-38 T 14-10-2018 IPR019688 Protein of unknown function DUF2533 C2I25_12130 52fa4844372714a3e6247036ec0bdaf0 231 Gene3D G3DSA:1.10.150.240 17 100 1.3E-78 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_12130 52fa4844372714a3e6247036ec0bdaf0 231 SUPERFAMILY SSF56784 3 229 2.21E-44 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_12130 52fa4844372714a3e6247036ec0bdaf0 231 Gene3D G3DSA:3.40.50.1000 6 223 1.3E-78 T 14-10-2018 IPR023214 HAD superfamily C2I25_12130 52fa4844372714a3e6247036ec0bdaf0 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 199 3.3E-22 T 14-10-2018 C2I25_12130 52fa4844372714a3e6247036ec0bdaf0 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 194 2.0E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_12130 52fa4844372714a3e6247036ec0bdaf0 231 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 225 2.0E-84 T 14-10-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PIRSF PIRSF000724 1 394 2.3E-159 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 Pfam PF00162 Phosphoglycerate kinase 6 383 2.0E-166 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 Gene3D G3DSA:3.40.50.1260 1 170 2.6E-76 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 SUPERFAMILY SSF53748 1 393 1.1E-163 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.102 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 Gene3D G3DSA:3.40.50.1260 177 381 1.7E-88 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13535 9db47b7ff49996d679349e5bfb9c8224 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 3.8E-97 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.2E-69 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 Gene3D G3DSA:3.50.50.60 163 285 1.4E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-36 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.7E-36 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.7E-36 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.7E-36 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.7E-36 T 14-10-2018 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 SUPERFAMILY SSF55424 350 472 2.58E-41 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 8.3E-38 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 Gene3D G3DSA:3.50.50.60 5 341 1.4E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 3.0E-177 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 2.5E-61 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 Gene3D G3DSA:3.30.390.30 353 473 4.5E-46 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 PIRSF PIRSF000350 1 469 8.8E-86 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 C2I25_18595 bb465ab4e22be2b6ec1176df25f77548 473 SUPERFAMILY SSF51905 1 377 3.05E-59 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 Gene3D G3DSA:3.30.565.10 347 499 3.1E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 SUPERFAMILY SSF55874 332 498 8.38E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 SUPERFAMILY SSF47384 259 343 6.08E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 390 488 2.3E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 SMART SM00387 389 500 1.0E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 SMART SM00304 216 268 4.5E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 Gene3D G3DSA:1.10.287.130 272 343 1.9E-20 T 14-10-2018 C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 9.1E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 9.1E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 SMART SM00388 276 343 4.4E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 341 2.5E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 SUPERFAMILY SSF158472 221 266 2.22E-6 T 14-10-2018 C2I25_10085 8ee400c0ba93757d89487e6af971eb02 501 Gene3D G3DSA:1.20.1480.50 198 271 3.6E-8 T 14-10-2018 C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 Pfam PF07702 UTRA domain 92 225 1.1E-32 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 2.0E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 2.0E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 Gene3D G3DSA:3.40.1410.10 74 228 4.4E-39 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 7.2E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 SUPERFAMILY SSF46785 4 71 3.7E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 SUPERFAMILY SSF64288 77 229 5.34E-40 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 SMART SM00345 8 67 9.4E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 Gene3D G3DSA:1.10.10.10 1 67 9.7E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20725 47b66c6f3c3c1f0eb11ecd915605aea7 235 SMART SM00866 90 227 1.3E-31 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_17770 ae6fca62d534baba9646cbb2cfe83f16 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 152 1.3E-43 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 C2I25_17770 ae6fca62d534baba9646cbb2cfe83f16 156 Gene3D G3DSA:3.40.390.30 3 156 5.0E-47 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 C2I25_17770 ae6fca62d534baba9646cbb2cfe83f16 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 156 24.703 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 C2I25_17770 ae6fca62d534baba9646cbb2cfe83f16 156 Pfam PF02130 Uncharacterized protein family UPF0054 13 151 6.6E-51 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 C2I25_17770 ae6fca62d534baba9646cbb2cfe83f16 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 14-10-2018 IPR020549 Endoribonuclease YbeY, conserved site C2I25_17770 ae6fca62d534baba9646cbb2cfe83f16 156 SUPERFAMILY SSF55486 2 155 1.42E-46 T 14-10-2018 C2I25_10820 130d703805aef3ddf286cbee1bcbd8ea 293 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10820 130d703805aef3ddf286cbee1bcbd8ea 293 SMART SM00382 32 223 6.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_10820 130d703805aef3ddf286cbee1bcbd8ea 293 Pfam PF00005 ABC transporter 24 174 1.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10820 130d703805aef3ddf286cbee1bcbd8ea 293 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 1.4E-122 T 14-10-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 C2I25_10820 130d703805aef3ddf286cbee1bcbd8ea 293 SUPERFAMILY SSF52540 19 237 1.7E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10820 130d703805aef3ddf286cbee1bcbd8ea 293 Gene3D G3DSA:3.40.50.300 2 287 7.9E-76 T 14-10-2018 C2I25_21295 f95b0d7571b3e765a6047f6ebf642746 267 Gene3D G3DSA:3.60.40.10 1 267 1.1E-21 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_21295 f95b0d7571b3e765a6047f6ebf642746 267 Pfam PF13672 Protein phosphatase 2C 14 221 6.7E-16 T 14-10-2018 C2I25_21295 f95b0d7571b3e765a6047f6ebf642746 267 SMART SM00332 1 265 8.6E-4 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_21295 f95b0d7571b3e765a6047f6ebf642746 267 SUPERFAMILY SSF81606 4 267 2.88E-20 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 7 361 5.2E-140 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 PIRSF PIRSF006809 1 418 3.8E-146 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 Pfam PF01926 50S ribosome-binding GTPase 200 325 8.7E-18 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 Hamap MF_00900 GTPase HflX [hflX]. 25 391 47.221 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 Pfam PF16360 GTP-binding GTPase Middle Region 112 192 3.0E-26 T 14-10-2018 IPR032305 GTP-binding protein, middle domain C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 SUPERFAMILY SSF52540 198 372 8.24E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 1.7E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 274 292 1.7E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 Pfam PF13167 GTP-binding GTPase N-terminal 23 110 4.5E-35 T 14-10-2018 IPR025121 GTPase HflX, N-terminal C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 Gene3D G3DSA:3.40.50.11060 16 136 9.6E-42 T 14-10-2018 C2I25_02505 3b716b4c60def3235c1d797262ee47c3 419 Gene3D G3DSA:3.40.50.300 197 368 4.1E-36 T 14-10-2018 C2I25_06280 19d031cac56d67625f641416f352366e 186 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 8 180 1.7E-62 T 14-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 C2I25_06280 19d031cac56d67625f641416f352366e 186 PIRSF PIRSF016897 1 186 1.3E-64 T 14-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 C2I25_06280 19d031cac56d67625f641416f352366e 186 Gene3D G3DSA:3.20.20.400 1 186 5.2E-70 T 14-10-2018 IPR035928 GlpP-like superfamily C2I25_06280 19d031cac56d67625f641416f352366e 186 SUPERFAMILY SSF110391 8 181 1.31E-62 T 14-10-2018 IPR035928 GlpP-like superfamily C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 176 8.4E-77 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 325 1.4E-140 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 PIRSF PIRSF000116 200 330 5.6E-15 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 PIRSF PIRSF000116 2 203 6.6E-44 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 327 44.645 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 SUPERFAMILY SSF51735 1 181 4.44E-73 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 SUPERFAMILY SSF48179 182 328 1.87E-70 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 Gene3D G3DSA:1.10.3730.40 181 335 3.2E-71 T 14-10-2018 C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 182 325 9.1E-67 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_02410 f9fe817cdb3964898aab1f73b93a2ae4 335 Gene3D G3DSA:3.40.50.720 1 180 3.5E-79 T 14-10-2018 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 PIRSF PIRSF000770 2 237 1.4E-92 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 Gene3D G3DSA:1.10.10.10 159 235 1.5E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 211 222 7.6E-14 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 77 90 7.6E-14 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 196 211 7.6E-14 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 175 187 7.6E-14 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 Gene3D G3DSA:1.20.120.1810 19 119 4.2E-24 T 14-10-2018 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 222 1.6E-30 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 Pfam PF04545 Sigma-70, region 4 172 222 2.9E-16 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 Pfam PF04542 Sigma-70 region 2 53 120 1.9E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 196 222 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 SUPERFAMILY SSF88946 10 118 8.9E-34 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 SUPERFAMILY SSF88659 138 223 2.24E-19 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_17580 27dce26354d3e86b8e4f9c675754002d 237 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 3 226 1.1E-112 T 14-10-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_09035 2f0c3d03209b1a3eb4fb3d6a66f4151d 39 Pfam PF14152 YfhE-like protein 2 37 2.5E-19 T 14-10-2018 IPR025437 YfhE-like protein C2I25_15275 e12ccf049c7140fd9d1b83f736ce568d 159 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 157 7.9E-75 T 14-10-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 C2I25_15275 e12ccf049c7140fd9d1b83f736ce568d 159 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.4E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_15275 e12ccf049c7140fd9d1b83f736ce568d 159 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.4E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_15275 e12ccf049c7140fd9d1b83f736ce568d 159 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_15275 e12ccf049c7140fd9d1b83f736ce568d 159 Gene3D G3DSA:3.90.79.10 1 157 8.6E-47 T 14-10-2018 C2I25_15275 e12ccf049c7140fd9d1b83f736ce568d 159 Pfam PF00293 NUDIX domain 28 95 9.2E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_15275 e12ccf049c7140fd9d1b83f736ce568d 159 SUPERFAMILY SSF55811 27 109 5.15E-22 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_05070 860f5ac1aaefb5102f7702cd63c973c2 299 Pfam PF00005 ABC transporter 19 158 1.7E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_05070 860f5ac1aaefb5102f7702cd63c973c2 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_05070 860f5ac1aaefb5102f7702cd63c973c2 299 SMART SM00382 27 231 3.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_05070 860f5ac1aaefb5102f7702cd63c973c2 299 SUPERFAMILY SSF52540 3 223 2.72E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05070 860f5ac1aaefb5102f7702cd63c973c2 299 Pfam PF13732 Domain of unknown function (DUF4162) 212 294 5.3E-18 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 C2I25_05070 860f5ac1aaefb5102f7702cd63c973c2 299 Gene3D G3DSA:3.40.50.300 1 232 5.2E-62 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 SUPERFAMILY SSF103491 1 422 1.31E-129 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 427 2.9E-147 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 431 29.636 T 14-10-2018 IPR026593 Protein translocase subunit SecY C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PIRSF PIRSF004557 1 433 2.1E-130 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 Pfam PF00344 SecY translocase 68 415 2.9E-114 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 Gene3D G3DSA:1.10.3370.10 1 427 2.3E-161 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 271 290 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 311 333 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 400 418 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 366 384 1.3E-101 T 14-10-2018 C2I25_10870 84895a7e7b893e1e7a2c487411595b69 433 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_16505 7414121f63dbf68542820c5e1a72d4f3 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 5.2E-112 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 C2I25_16505 7414121f63dbf68542820c5e1a72d4f3 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 5.4E-24 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 C2I25_16505 7414121f63dbf68542820c5e1a72d4f3 344 SUPERFAMILY SSF46589 16 100 1.15E-21 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 C2I25_16505 7414121f63dbf68542820c5e1a72d4f3 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 48.957 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 C2I25_16505 7414121f63dbf68542820c5e1a72d4f3 344 SUPERFAMILY SSF55681 93 342 1.49E-83 T 14-10-2018 C2I25_16505 7414121f63dbf68542820c5e1a72d4f3 344 Gene3D G3DSA:3.30.930.10 8 343 3.5E-126 T 14-10-2018 C2I25_16505 7414121f63dbf68542820c5e1a72d4f3 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 1.1E-115 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 C2I25_18100 a13cdb2ead7922bf9e35dc420b224e45 99 Gene3D G3DSA:3.30.700.10 7 98 2.6E-8 T 14-10-2018 C2I25_18100 a13cdb2ead7922bf9e35dc420b224e45 99 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 2.7E-6 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I25_18100 a13cdb2ead7922bf9e35dc420b224e45 99 SUPERFAMILY SSF54523 7 82 8.63E-14 T 14-10-2018 C2I25_18100 a13cdb2ead7922bf9e35dc420b224e45 99 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 2.1E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I25_18100 a13cdb2ead7922bf9e35dc420b224e45 99 PIRSF PIRSF029928 1 97 3.7E-34 T 14-10-2018 IPR016940 ComG operon protein C GO:0030420 C2I25_18100 a13cdb2ead7922bf9e35dc420b224e45 99 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 1.9E-10 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 C2I25_18100 a13cdb2ead7922bf9e35dc420b224e45 99 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 1.9E-10 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 C2I25_18100 a13cdb2ead7922bf9e35dc420b224e45 99 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I25_24125 d0e09c28ecf7cf7b759c102b88e7d89a 285 SUPERFAMILY SSF56281 25 254 7.99E-43 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_24125 d0e09c28ecf7cf7b759c102b88e7d89a 285 SMART SM00849 38 248 3.3E-32 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_24125 d0e09c28ecf7cf7b759c102b88e7d89a 285 Gene3D G3DSA:3.60.15.10 16 271 3.0E-38 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_24125 d0e09c28ecf7cf7b759c102b88e7d89a 285 Pfam PF00753 Metallo-beta-lactamase superfamily 39 248 2.6E-34 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 PIRSF PIRSF000193 2 268 2.5E-83 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 1.9E-39 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 1.9E-85 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 SUPERFAMILY SSF51735 3 160 2.85E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 Gene3D G3DSA:1.10.3730.10 165 266 5.6E-39 T 14-10-2018 C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 4.2E-18 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 26.633 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 SUPERFAMILY SSF48179 161 268 2.21E-38 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_27335 2401cbfc8855363b07c72d99270eeab7 272 Gene3D G3DSA:3.40.50.720 1 164 1.3E-49 T 14-10-2018 C2I25_14330 24fd1301aae7c42412ddf73d03439789 367 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 348 2.3E-124 T 14-10-2018 IPR039480 C-C bond lyase-like C2I25_14330 24fd1301aae7c42412ddf73d03439789 367 Gene3D G3DSA:3.20.20.60 12 353 2.1E-14 T 14-10-2018 C2I25_14330 24fd1301aae7c42412ddf73d03439789 367 SUPERFAMILY SSF51621 34 292 3.14E-21 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I25_14330 24fd1301aae7c42412ddf73d03439789 367 PIRSF PIRSF015582 14 358 3.3E-84 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like C2I25_22545 29f5e3cb1e9e3c8dcff434b89f94a7cc 159 SMART SM00871 2 157 1.4E-4 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_22545 29f5e3cb1e9e3c8dcff434b89f94a7cc 159 Pfam PF14526 Integron-associated effector binding protein 5 156 1.3E-30 T 14-10-2018 IPR029441 Integron-associated effector binding protein C2I25_22545 29f5e3cb1e9e3c8dcff434b89f94a7cc 159 Gene3D G3DSA:3.20.80.10 2 159 6.8E-16 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_28555 d262c6ca968a71b5ab2fa7e1f33d54fd 198 SUPERFAMILY SSF55729 33 150 3.01E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_28555 d262c6ca968a71b5ab2fa7e1f33d54fd 198 Gene3D G3DSA:3.40.630.30 17 162 3.7E-7 T 14-10-2018 C2I25_28510 d262c6ca968a71b5ab2fa7e1f33d54fd 198 SUPERFAMILY SSF55729 33 150 3.01E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_28510 d262c6ca968a71b5ab2fa7e1f33d54fd 198 Gene3D G3DSA:3.40.630.30 17 162 3.7E-7 T 14-10-2018 C2I25_00035 d262c6ca968a71b5ab2fa7e1f33d54fd 198 SUPERFAMILY SSF55729 33 150 3.01E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_00035 d262c6ca968a71b5ab2fa7e1f33d54fd 198 Gene3D G3DSA:3.40.630.30 17 162 3.7E-7 T 14-10-2018 C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 SMART SM00387 302 406 5.2E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 303 405 6.7E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 366 2.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 385 2.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 352 2.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 404 2.5E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 SUPERFAMILY SSF55874 258 405 4.98E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 Gene3D G3DSA:3.30.565.10 260 406 3.0E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15345 ec94ee13bb326f63fbe874b88b13c392 406 Gene3D G3DSA:1.10.287.130 182 259 3.1E-5 T 14-10-2018 C2I25_19790 80ea5a3ec277b64599b3aa90cced1260 110 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 5 109 4.8E-45 T 14-10-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 C2I25_19790 80ea5a3ec277b64599b3aa90cced1260 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 28 101 8.9E-14 T 14-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 C2I25_22240 540ea491d554974454b88233949b13e1 375 Pfam PF00144 Beta-lactamase 76 359 4.1E-56 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_22240 540ea491d554974454b88233949b13e1 375 SUPERFAMILY SSF56601 56 360 9.66E-78 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_22240 540ea491d554974454b88233949b13e1 375 Gene3D G3DSA:3.40.710.10 60 365 4.0E-78 T 14-10-2018 C2I25_09230 99ad9e5c5f2110d56b47b20fb959513a 178 ProSitePatterns PS00761 Signal peptidases I signature 3. 135 148 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I25_09230 99ad9e5c5f2110d56b47b20fb959513a 178 Pfam PF00717 Peptidase S24-like 34 99 1.8E-16 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I25_09230 99ad9e5c5f2110d56b47b20fb959513a 178 SUPERFAMILY SSF51306 27 177 4.97E-45 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I25_09230 99ad9e5c5f2110d56b47b20fb959513a 178 Gene3D G3DSA:2.10.109.10 37 168 1.2E-32 T 14-10-2018 C2I25_09230 99ad9e5c5f2110d56b47b20fb959513a 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 76 88 4.5E-19 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_09230 99ad9e5c5f2110d56b47b20fb959513a 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 130 149 4.5E-19 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_09230 99ad9e5c5f2110d56b47b20fb959513a 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 4.5E-19 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_09230 99ad9e5c5f2110d56b47b20fb959513a 178 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 171 8.3E-49 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_00375 716a1997baf953acce0352418f532deb 304 SUPERFAMILY SSF53474 11 304 2.68E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_00375 716a1997baf953acce0352418f532deb 304 Pfam PF00561 alpha/beta hydrolase fold 32 291 3.0E-26 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_00375 716a1997baf953acce0352418f532deb 304 Gene3D G3DSA:3.40.50.1820 9 304 1.9E-52 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_00375 716a1997baf953acce0352418f532deb 304 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 62 73 9.6E-10 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 C2I25_00375 716a1997baf953acce0352418f532deb 304 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 34 42 9.6E-10 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 C2I25_00375 716a1997baf953acce0352418f532deb 304 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 105 119 9.6E-10 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 C2I25_02015 b6a448a7aaab31f83a7a19eb5b2ef19a 200 Gene3D G3DSA:3.40.109.10 5 200 6.5E-79 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_02015 b6a448a7aaab31f83a7a19eb5b2ef19a 200 SUPERFAMILY SSF55469 7 200 2.22E-65 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_02015 b6a448a7aaab31f83a7a19eb5b2ef19a 200 Pfam PF00881 Nitroreductase family 12 179 1.8E-22 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_25995 b35a97bbde48e8161488d462e8bdccbf 255 SUPERFAMILY SSF54001 3 254 9.57E-64 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_25995 b35a97bbde48e8161488d462e8bdccbf 255 Pfam PF00797 N-acetyltransferase 23 255 7.3E-43 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_25995 b35a97bbde48e8161488d462e8bdccbf 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 102 127 2.7E-8 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_25995 b35a97bbde48e8161488d462e8bdccbf 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 2.7E-8 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_25995 b35a97bbde48e8161488d462e8bdccbf 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 2.7E-8 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_25995 b35a97bbde48e8161488d462e8bdccbf 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 2.7E-8 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_25995 b35a97bbde48e8161488d462e8bdccbf 255 Gene3D G3DSA:3.30.2140.20 1 255 4.4E-78 T 14-10-2018 C2I25_01105 2322fd7687b966b994ca0322c3ea2105 328 Gene3D G3DSA:3.40.50.720 122 267 1.5E-100 T 14-10-2018 C2I25_01105 2322fd7687b966b994ca0322c3ea2105 328 SUPERFAMILY SSF51735 111 271 5.97E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_01105 2322fd7687b966b994ca0322c3ea2105 328 SUPERFAMILY SSF50129 1 148 5.17E-37 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_01105 2322fd7687b966b994ca0322c3ea2105 328 SMART SM00829 10 322 1.1E-57 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_01105 2322fd7687b966b994ca0322c3ea2105 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 6.3E-11 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_01105 2322fd7687b966b994ca0322c3ea2105 328 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 C2I25_01105 2322fd7687b966b994ca0322c3ea2105 328 Pfam PF00107 Zinc-binding dehydrogenase 150 278 4.5E-31 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_01105 2322fd7687b966b994ca0322c3ea2105 328 Gene3D G3DSA:3.90.180.10 10 318 1.5E-100 T 14-10-2018 C2I25_18385 e45547010857acbabf53942a6f456457 214 Gene3D G3DSA:3.30.300.270 98 213 7.7E-34 T 14-10-2018 IPR038503 Stage III sporulation protein AH-like superfamily C2I25_18385 e45547010857acbabf53942a6f456457 214 Pfam PF12685 SpoIIIAH-like protein 5 201 5.7E-36 T 14-10-2018 IPR024232 Stage III sporulation protein AH-like C2I25_07695 8d7ca91316a02895aa50a26ee2d2b071 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 261 2.9E-109 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_07695 8d7ca91316a02895aa50a26ee2d2b071 270 SUPERFAMILY SSF53613 1 263 9.51E-86 T 14-10-2018 IPR029056 Ribokinase-like C2I25_07695 8d7ca91316a02895aa50a26ee2d2b071 270 Pfam PF08543 Phosphomethylpyrimidine kinase 13 259 5.5E-102 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 C2I25_07695 8d7ca91316a02895aa50a26ee2d2b071 270 Gene3D G3DSA:3.40.1190.20 1 268 7.1E-108 T 14-10-2018 IPR029056 Ribokinase-like C2I25_17260 939422cc6232ada2da4d496b7e91cf45 255 SUPERFAMILY SSF69572 4 241 9.29E-63 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I25_17260 939422cc6232ada2da4d496b7e91cf45 255 Gene3D G3DSA:3.40.50.720 1 255 4.1E-82 T 14-10-2018 C2I25_17260 939422cc6232ada2da4d496b7e91cf45 255 Pfam PF00899 ThiF family 6 158 1.5E-37 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I25_21080 297a9687c09626043dcd6de851f1269b 73 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 69 3.1E-30 T 14-10-2018 IPR005359 Protein with unknown function UPF0154 C2I25_21080 297a9687c09626043dcd6de851f1269b 73 Hamap MF_00363 UPF0154 protein . 2 72 21.922 T 14-10-2018 IPR005359 Protein with unknown function UPF0154 C2I25_21080 297a9687c09626043dcd6de851f1269b 73 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 41 1.0E-7 T 14-10-2018 IPR005359 Protein with unknown function UPF0154 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 6.7E-32 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 1.5E-140 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 14-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 Gene3D G3DSA:3.30.590.10 108 444 4.0E-147 T 14-10-2018 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 SUPERFAMILY SSF55931 105 442 1.37E-130 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 SUPERFAMILY SSF54368 5 104 6.93E-35 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 SMART SM01230 105 354 1.2E-141 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 2.7E-185 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I25_21010 b919b615a5531a56dcbffbab349d1fa9 444 Gene3D G3DSA:3.10.20.70 2 107 1.2E-44 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I25_13740 85e5fe8ab1755f3434163b5a8a4d4e24 404 Pfam PF07690 Major Facilitator Superfamily 24 331 6.2E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_13740 85e5fe8ab1755f3434163b5a8a4d4e24 404 PRINTS PR01035 Tetracycline resistance protein signature 114 135 5.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_13740 85e5fe8ab1755f3434163b5a8a4d4e24 404 PRINTS PR01035 Tetracycline resistance protein signature 26 42 5.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_13740 85e5fe8ab1755f3434163b5a8a4d4e24 404 PRINTS PR01035 Tetracycline resistance protein signature 378 397 5.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_13740 85e5fe8ab1755f3434163b5a8a4d4e24 404 PRINTS PR01035 Tetracycline resistance protein signature 56 75 5.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_13740 85e5fe8ab1755f3434163b5a8a4d4e24 404 PRINTS PR01035 Tetracycline resistance protein signature 174 194 5.6E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_13740 85e5fe8ab1755f3434163b5a8a4d4e24 404 Gene3D G3DSA:1.20.1250.20 9 396 2.0E-49 T 14-10-2018 C2I25_13740 85e5fe8ab1755f3434163b5a8a4d4e24 404 SUPERFAMILY SSF103473 12 396 1.2E-60 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_02845 59f2e5afae35aa223bb5aec97df192db 188 Pfam PF08281 Sigma-70, region 4 121 174 6.6E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_02845 59f2e5afae35aa223bb5aec97df192db 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 177 4.9E-27 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_02845 59f2e5afae35aa223bb5aec97df192db 188 Gene3D G3DSA:1.10.1740.10 5 90 8.1E-15 T 14-10-2018 C2I25_02845 59f2e5afae35aa223bb5aec97df192db 188 Pfam PF04542 Sigma-70 region 2 24 94 1.8E-10 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_02845 59f2e5afae35aa223bb5aec97df192db 188 Gene3D G3DSA:1.10.10.10 105 180 1.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02845 59f2e5afae35aa223bb5aec97df192db 188 SUPERFAMILY SSF88946 4 111 4.97E-17 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_02845 59f2e5afae35aa223bb5aec97df192db 188 SUPERFAMILY SSF88659 105 178 4.49E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_02215 700e4c4010e1fd95fa5a13e236bc9b85 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 37.316 T 14-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 C2I25_02215 700e4c4010e1fd95fa5a13e236bc9b85 223 SUPERFAMILY SSF51569 1 214 3.87E-83 T 14-10-2018 C2I25_02215 700e4c4010e1fd95fa5a13e236bc9b85 223 Gene3D G3DSA:3.20.20.70 1 218 1.2E-96 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_02215 700e4c4010e1fd95fa5a13e236bc9b85 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 211 6.2E-93 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I25_02215 700e4c4010e1fd95fa5a13e236bc9b85 223 PIRSF PIRSF001357 1 223 2.9E-80 T 14-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I25_02215 700e4c4010e1fd95fa5a13e236bc9b85 223 Pfam PF01791 DeoC/LacD family aldolase 4 205 4.0E-23 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I25_02215 700e4c4010e1fd95fa5a13e236bc9b85 223 SMART SM01133 2 214 1.2E-104 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 1.6E-5 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 1.6E-5 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 SMART SM01134 75 241 1.3E-56 T 14-10-2018 C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 Pfam PF00455 DeoR C terminal sensor domain 77 240 4.2E-43 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 Gene3D G3DSA:1.10.10.10 1 56 2.6E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 SMART SM00420 8 60 4.6E-11 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 SUPERFAMILY SSF46785 6 62 3.24E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 3.9E-12 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_04775 4fbb8594907f62de6deec6c3bb669387 260 SUPERFAMILY SSF100950 75 241 6.51E-32 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_24945 bb6728da85c916135b4d23306de83d8c 169 Pfam PF04167 Protein of unknown function (DUF402) 64 129 1.3E-13 T 14-10-2018 IPR007295 Domain of unknown function DUF402 C2I25_24945 bb6728da85c916135b4d23306de83d8c 169 SUPERFAMILY SSF159234 23 145 4.71E-28 T 14-10-2018 IPR035930 FomD-like superfamily C2I25_24945 bb6728da85c916135b4d23306de83d8c 169 Gene3D G3DSA:2.40.380.10 21 144 2.5E-6 T 14-10-2018 IPR035930 FomD-like superfamily C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 Pfam PF00318 Ribosomal protein S2 9 224 3.9E-102 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.0E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.0E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.0E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.0E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.0E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.0E-40 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 SUPERFAMILY SSF52313 6 227 3.66E-100 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 1.8E-113 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 Gene3D G3DSA:3.40.50.10490 10 215 1.3E-95 T 14-10-2018 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 Gene3D G3DSA:1.10.287.610 97 152 1.3E-95 T 14-10-2018 C2I25_20375 3da42f77a941a2e1b2ff08736aec3b60 233 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 43.783 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 TIGRFAM TIGR00767 rho: transcription termination factor Rho 4 412 1.1E-204 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 SMART SM00382 168 353 1.2E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 SMART SM00357 54 119 1.2E-19 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 SUPERFAMILY SSF50249 51 114 3.48E-7 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 Pfam PF07498 Rho termination factor, N-terminal domain 8 49 4.5E-15 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 Gene3D G3DSA:3.40.50.300 131 413 8.4E-123 T 14-10-2018 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 222.558 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 Gene3D G3DSA:1.10.720.10 1 47 1.6E-20 T 14-10-2018 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 Gene3D G3DSA:2.40.50.140 48 124 1.0E-29 T 14-10-2018 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 SUPERFAMILY SSF68912 4 49 1.1E-10 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 SMART SM00959 7 49 3.1E-15 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 158 361 2.5E-18 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 SUPERFAMILY SSF52540 91 369 6.64E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12505 079fb7631f2b5d33344d11484b27fa8a 423 Pfam PF07497 Rho termination factor, RNA-binding domain 53 126 2.3E-31 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 C2I25_09670 b5fe610dd5c4a636bc1a450bf9f6693d 231 Gene3D G3DSA:3.40.630.30 18 176 2.5E-6 T 14-10-2018 C2I25_09670 b5fe610dd5c4a636bc1a450bf9f6693d 231 SUPERFAMILY SSF55729 18 165 2.61E-9 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_00565 3342d36d2217af83dd80e7bc2bb0c75c 429 Pfam PF01391 Collagen triple helix repeat (20 copies) 202 260 6.0E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_00565 3342d36d2217af83dd80e7bc2bb0c75c 429 TIGRFAM TIGR03721 exospore_TM: BclB C-terminal domain 259 427 3.5E-50 T 14-10-2018 IPR021210 Exosporium BclB, C-terminal C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.8E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 SUPERFAMILY SSF53383 87 464 3.38E-86 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 Gene3D G3DSA:1.10.10.10 3 78 1.4E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 SUPERFAMILY SSF46785 11 83 7.22E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 Pfam PF00155 Aminotransferase class I and II 107 460 4.2E-23 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 Gene3D G3DSA:3.40.640.10 92 459 5.9E-119 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 9.1E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_10040 6f3c382d1d3993258232e48c9a88066f 470 SMART SM00345 18 77 2.1E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_17070 83aa2c3d3931b294369ee17b909cd430 182 Gene3D G3DSA:1.10.287.130 1 57 2.0E-20 T 14-10-2018 C2I25_17070 83aa2c3d3931b294369ee17b909cd430 182 SMART SM01317 59 171 2.2E-61 T 14-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal C2I25_17070 83aa2c3d3931b294369ee17b909cd430 182 Gene3D G3DSA:3.30.565.30 58 174 1.1E-30 T 14-10-2018 IPR037100 Sporulation initiation phosphotransferase B, C-terminal domain superfamily C2I25_17070 83aa2c3d3931b294369ee17b909cd430 182 SUPERFAMILY SSF55890 2 173 2.09E-62 T 14-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I25_17070 83aa2c3d3931b294369ee17b909cd430 182 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 60 169 5.3E-37 T 14-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal C2I25_17070 83aa2c3d3931b294369ee17b909cd430 182 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 5 56 2.8E-17 T 14-10-2018 IPR039506 SpoOB, alpha-helical domain C2I25_08960 f9750387699f02c3e8612a5803f4a805 586 SUPERFAMILY SSF90123 5 324 2.22E-78 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_08960 f9750387699f02c3e8612a5803f4a805 586 Gene3D G3DSA:3.40.50.300 331 583 3.9E-91 T 14-10-2018 C2I25_08960 f9750387699f02c3e8612a5803f4a805 586 Pfam PF00664 ABC transporter transmembrane region 20 294 1.1E-39 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_08960 f9750387699f02c3e8612a5803f4a805 586 SUPERFAMILY SSF52540 331 578 6.01E-95 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08960 f9750387699f02c3e8612a5803f4a805 586 Gene3D G3DSA:1.20.1560.10 4 324 1.5E-110 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_08960 f9750387699f02c3e8612a5803f4a805 586 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_08960 f9750387699f02c3e8612a5803f4a805 586 Pfam PF00005 ABC transporter 358 507 1.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_08960 f9750387699f02c3e8612a5803f4a805 586 SMART SM00382 367 553 2.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_28225 17c75237921c1b33f16dc39f1b03b5a2 351 SUPERFAMILY SSF52096 3 332 3.22E-59 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_28225 17c75237921c1b33f16dc39f1b03b5a2 351 Pfam PF16113 Enoyl-CoA hydratase/isomerase 15 346 3.2E-119 T 14-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 C2I25_28225 17c75237921c1b33f16dc39f1b03b5a2 351 Gene3D G3DSA:3.90.226.40 1 351 6.3E-116 T 14-10-2018 C2I25_11990 b441203347c4cf31c2731c470a693db9 344 Pfam PF01594 AI-2E family transporter 16 333 1.2E-44 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like C2I25_03875 1277e154159be6984b2a068b71016358 340 Gene3D G3DSA:1.10.1040.10 190 336 4.2E-54 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_03875 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 3.2E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 3.2E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 3.2E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 3.2E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 3.2E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 3.2E-47 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 PIRSF PIRSF000114 1 333 9.5E-111 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 SUPERFAMILY SSF51735 3 179 2.02E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_03875 1277e154159be6984b2a068b71016358 340 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 161 4.8E-57 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 Gene3D G3DSA:3.40.50.720 1 188 4.7E-66 T 14-10-2018 C2I25_03875 1277e154159be6984b2a068b71016358 340 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 1.3E-55 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_03875 1277e154159be6984b2a068b71016358 340 SUPERFAMILY SSF48179 181 332 9.52E-59 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_03875 1277e154159be6984b2a068b71016358 340 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 39.147 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 Gene3D G3DSA:2.60.120.1250 42 169 1.2E-45 T 14-10-2018 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 Gene3D G3DSA:1.10.390.30 303 463 2.6E-56 T 14-10-2018 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 SMART SM00495 697 743 3.7E-4 T 14-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 SMART SM00060 606 679 3.1E-8 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 Pfam PF03272 Putative mucin or carbohydrate-binding module 477 590 2.8E-27 T 14-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 165 425 1.6E-55 T 14-10-2018 IPR031161 Peptidase family M60 domain C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 Pfam PF17291 N-terminal domain of M60-like peptidases 82 153 3.2E-15 T 14-10-2018 IPR035423 M60-like domain, N-terminal C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 Gene3D G3DSA:1.10.1740.210 170 301 8.2E-42 T 14-10-2018 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 SUPERFAMILY SSF49265 600 691 4.06E-14 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 SUPERFAMILY SSF51055 699 741 1.7E-5 T 14-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 Gene3D G3DSA:2.60.40.10 604 690 4.5E-23 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 Gene3D G3DSA:2.10.10.20 696 744 7.8E-8 T 14-10-2018 C2I25_21985 13fe3908ae04f9fc443dcd710b7e0146 746 SMART SM01276 82 375 8.5E-104 T 14-10-2018 IPR031161 Peptidase family M60 domain C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 14-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 Gene3D G3DSA:3.20.20.150 1 298 2.0E-102 T 14-10-2018 C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 SMART SM00518 3 286 3.5E-121 T 14-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 283 6.2E-97 T 14-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 214 230 - T 14-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 286 40.735 T 14-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 176 183 - T 14-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 Pfam PF01261 Xylose isomerase-like TIM barrel 22 238 8.6E-35 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain C2I25_17860 c6b3af3d9eeecd41d7e70c0f561ac7e9 298 SUPERFAMILY SSF51658 2 295 2.23E-99 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily C2I25_09635 412d226f80e22b3919f7badfda5b5689 187 SUPERFAMILY SSF52833 1 187 9.78E-55 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_09635 412d226f80e22b3919f7badfda5b5689 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 2.7E-105 T 14-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I25_09635 412d226f80e22b3919f7badfda5b5689 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 7.1E-5 T 14-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I25_09635 412d226f80e22b3919f7badfda5b5689 187 Gene3D G3DSA:3.40.30.10 1 186 2.0E-59 T 14-10-2018 C2I25_09635 412d226f80e22b3919f7badfda5b5689 187 PIRSF PIRSF000239 1 187 1.5E-49 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I25_09635 412d226f80e22b3919f7badfda5b5689 187 Pfam PF00578 AhpC/TSA family 4 133 3.6E-32 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I25_04790 84838905618ccd30156fd4de79c8f7de 264 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 264 131.188 T 14-10-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 C2I25_04790 84838905618ccd30156fd4de79c8f7de 264 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 195 3.5E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_04790 84838905618ccd30156fd4de79c8f7de 264 Gene3D G3DSA:1.10.150.240 21 98 9.4E-115 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_04790 84838905618ccd30156fd4de79c8f7de 264 SUPERFAMILY SSF56784 2 255 8.12E-66 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_04790 84838905618ccd30156fd4de79c8f7de 264 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 201 3.8E-17 T 14-10-2018 C2I25_04790 84838905618ccd30156fd4de79c8f7de 264 Gene3D G3DSA:3.40.50.1000 3 253 9.4E-115 T 14-10-2018 IPR023214 HAD superfamily C2I25_04790 84838905618ccd30156fd4de79c8f7de 264 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 2 254 2.6E-116 T 14-10-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 SUPERFAMILY SSF54211 189 326 7.97E-38 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 643 27.42 T 14-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 Gene3D G3DSA:3.30.230.10 214 325 1.1E-33 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 4.1E-37 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 SMART SM01340 208 326 2.0E-56 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 SUPERFAMILY SSF118116 457 645 1.7E-54 T 14-10-2018 IPR037198 MutL, C-terminal domain superfamily C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 Pfam PF08676 MutL C terminal dimerisation domain 461 603 5.2E-46 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 SUPERFAMILY SSF55874 3 212 6.16E-52 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 3.1E-99 T 14-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 Gene3D G3DSA:3.30.565.10 1 212 1.1E-63 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 14-10-2018 IPR014762 DNA mismatch repair, conserved site C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 SMART SM00853 461 603 3.8E-52 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 Gene3D G3DSA:3.30.1370.100 503 596 2.7E-63 T 14-10-2018 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 120 4.3E-12 T 14-10-2018 C2I25_20675 2cc1d38621e66de58afb1b1d83f94639 647 Gene3D G3DSA:2.30.42.20 462 645 2.7E-63 T 14-10-2018 C2I25_01800 c82bc69c6dea383ad2675f354ffca6cb 287 Pfam PF01522 Polysaccharide deacetylase 79 196 3.5E-34 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_01800 c82bc69c6dea383ad2675f354ffca6cb 287 SUPERFAMILY SSF88713 41 268 1.09E-67 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_01800 c82bc69c6dea383ad2675f354ffca6cb 287 Gene3D G3DSA:3.20.20.370 61 280 4.4E-91 T 14-10-2018 C2I25_18585 bb214655324a41e1675668584a565504 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 134 156 2.3E-22 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_18585 bb214655324a41e1675668584a565504 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 288 299 2.3E-22 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_18585 bb214655324a41e1675668584a565504 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 68 82 2.3E-22 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_18585 bb214655324a41e1675668584a565504 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 178 198 2.3E-22 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_18585 bb214655324a41e1675668584a565504 366 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 17 132 1.2E-26 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_18585 bb214655324a41e1675668584a565504 366 SUPERFAMILY SSF53223 6 145 8.64E-48 T 14-10-2018 C2I25_18585 bb214655324a41e1675668584a565504 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 150 202 1.2E-5 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_18585 bb214655324a41e1675668584a565504 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 220 349 2.1E-10 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_18585 bb214655324a41e1675668584a565504 366 PIRSF PIRSF000188 3 355 4.1E-166 T 14-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 C2I25_18585 bb214655324a41e1675668584a565504 366 Gene3D G3DSA:3.40.50.720 136 338 4.2E-153 T 14-10-2018 C2I25_18585 bb214655324a41e1675668584a565504 366 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 76 89 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_18585 bb214655324a41e1675668584a565504 366 SUPERFAMILY SSF51735 143 349 1.3E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_18585 bb214655324a41e1675668584a565504 366 Gene3D G3DSA:3.40.50.10860 12 345 4.2E-153 T 14-10-2018 C2I25_18585 bb214655324a41e1675668584a565504 366 SMART SM00839 146 353 5.5E-70 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_27370 3de1502d5328dbd5a50bc5bae2f2775c 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 429 1.3E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_27370 3de1502d5328dbd5a50bc5bae2f2775c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 430 7.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27370 3de1502d5328dbd5a50bc5bae2f2775c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 7.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27370 3de1502d5328dbd5a50bc5bae2f2775c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 7.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27370 3de1502d5328dbd5a50bc5bae2f2775c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 386 7.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27370 3de1502d5328dbd5a50bc5bae2f2775c 438 Gene3D G3DSA:3.30.565.10 282 432 9.0E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_27370 3de1502d5328dbd5a50bc5bae2f2775c 438 SMART SM00387 321 433 1.3E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_27370 3de1502d5328dbd5a50bc5bae2f2775c 438 SUPERFAMILY SSF55874 283 429 3.01E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_06485 388d1b383fb8b07271fef341ad10230c 302 Pfam PF12697 Alpha/beta hydrolase family 63 280 2.5E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_06485 388d1b383fb8b07271fef341ad10230c 302 Gene3D G3DSA:3.40.50.1820 9 299 1.7E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_06485 388d1b383fb8b07271fef341ad10230c 302 SUPERFAMILY SSF53474 32 297 4.05E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_15000 04ebb29cf9a052527e406d16c8b31445 340 SUPERFAMILY SSF55874 162 323 5.5E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15000 04ebb29cf9a052527e406d16c8b31445 340 SMART SM00387 215 327 4.4E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15000 04ebb29cf9a052527e406d16c8b31445 340 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 216 322 4.4E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15000 04ebb29cf9a052527e406d16c8b31445 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 324 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15000 04ebb29cf9a052527e406d16c8b31445 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 267 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15000 04ebb29cf9a052527e406d16c8b31445 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 305 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15000 04ebb29cf9a052527e406d16c8b31445 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 281 4.8E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15000 04ebb29cf9a052527e406d16c8b31445 340 Gene3D G3DSA:3.30.565.10 145 323 7.6E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_03790 9192694ec1755a6cf8d247a5e815efba 170 SUPERFAMILY SSF50022 6 160 1.57E-30 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I25_03790 9192694ec1755a6cf8d247a5e815efba 170 Pfam PF00355 Rieske [2Fe-2S] domain 51 149 4.2E-14 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 C2I25_03790 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 121 133 1.5E-5 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I25_03790 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 97 108 1.5E-5 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I25_03790 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 133 145 1.5E-5 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I25_03790 9192694ec1755a6cf8d247a5e815efba 170 Gene3D G3DSA:2.102.10.10 40 166 5.2E-27 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I25_08200 0a6675ca4f2b796dd542147aa2bd467d 339 SUPERFAMILY SSF52540 5 255 8.24E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08200 0a6675ca4f2b796dd542147aa2bd467d 339 Gene3D G3DSA:3.40.50.300 3 336 1.9E-98 T 14-10-2018 C2I25_08200 0a6675ca4f2b796dd542147aa2bd467d 339 SMART SM00382 34 241 2.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08200 0a6675ca4f2b796dd542147aa2bd467d 339 Pfam PF00005 ABC transporter 26 183 2.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_08200 0a6675ca4f2b796dd542147aa2bd467d 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 4.6E-23 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_08200 0a6675ca4f2b796dd542147aa2bd467d 339 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_08200 0a6675ca4f2b796dd542147aa2bd467d 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 292 4.2E-16 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Gene3D G3DSA:3.30.930.10 495 699 1.7E-62 T 14-10-2018 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Gene3D G3DSA:2.40.50.140 40 161 1.1E-68 T 14-10-2018 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 799 46.822 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Gene3D G3DSA:3.30.56.10 4 189 1.1E-68 T 14-10-2018 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Pfam PF03484 tRNA synthetase B5 domain 414 479 1.2E-17 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Pfam PF03483 B3/4 domain 222 394 2.8E-67 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 SMART SM00874 411 479 9.7E-26 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 805 1.3E-268 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Pfam PF03147 Ferredoxin-fold anticodon binding domain 712 805 6.3E-31 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 SUPERFAMILY SSF54991 708 805 2.09E-32 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 SUPERFAMILY SSF56037 208 405 8.37E-72 T 14-10-2018 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 SUPERFAMILY SSF55681 475 695 4.92E-51 T 14-10-2018 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Gene3D G3DSA:3.30.56.10 410 483 1.0E-23 T 14-10-2018 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Gene3D G3DSA:3.50.40.10 204 405 5.4E-83 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 SMART SM00896 712 805 4.0E-46 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Pfam PF01588 Putative tRNA binding domain 46 152 8.2E-27 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 Gene3D G3DSA:3.30.70.380 713 806 2.7E-32 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 SUPERFAMILY SSF50249 36 199 5.39E-49 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 SUPERFAMILY SSF46955 412 483 7.23E-18 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_16510 a590f88a4eeb2ebc2e0f756dace202a7 806 SMART SM00873 221 394 6.7E-92 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 C2I25_24315 dffa31734c56b6f8d9d3e82437211dc0 265 Gene3D G3DSA:3.10.180.10 166 249 1.1E-5 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24315 dffa31734c56b6f8d9d3e82437211dc0 265 Gene3D G3DSA:3.10.180.10 1 159 1.8E-53 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24315 dffa31734c56b6f8d9d3e82437211dc0 265 SUPERFAMILY SSF54593 2 148 1.0E-7 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24315 dffa31734c56b6f8d9d3e82437211dc0 265 Pfam PF13468 Glyoxalase-like domain 4 193 4.2E-45 T 14-10-2018 IPR025870 Glyoxalase-like domain C2I25_20205 90713fc8264d2984e3efed21b885733b 214 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 1.1E-92 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I25_20205 90713fc8264d2984e3efed21b885733b 214 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I25_20205 90713fc8264d2984e3efed21b885733b 214 SUPERFAMILY SSF51366 1 213 2.09E-81 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I25_20205 90713fc8264d2984e3efed21b885733b 214 Gene3D G3DSA:3.20.20.70 1 214 7.3E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_20205 90713fc8264d2984e3efed21b885733b 214 PIRSF PIRSF001461 1 214 1.1E-101 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I25_20205 90713fc8264d2984e3efed21b885733b 214 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 2.3E-97 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I25_20205 90713fc8264d2984e3efed21b885733b 214 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I25_12680 66d81141deeb12609a39f5ec0064317c 122 Gene3D G3DSA:1.20.58.1610 1 121 2.0E-43 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12680 66d81141deeb12609a39f5ec0064317c 122 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 5 122 19.659 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 C2I25_12680 66d81141deeb12609a39f5ec0064317c 122 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 121 7.9E-38 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_16445 61ae229658a51ef01d55a09302983729 118 Gene3D G3DSA:1.10.720.90 2 55 1.3E-26 T 14-10-2018 C2I25_16445 61ae229658a51ef01d55a09302983729 118 Pfam PF00453 Ribosomal protein L20 3 109 1.2E-50 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16445 61ae229658a51ef01d55a09302983729 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.563 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16445 61ae229658a51ef01d55a09302983729 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 4.0E-14 T 14-10-2018 C2I25_16445 61ae229658a51ef01d55a09302983729 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16445 61ae229658a51ef01d55a09302983729 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.8E-51 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16445 61ae229658a51ef01d55a09302983729 118 SUPERFAMILY SSF74731 2 116 1.2E-50 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16445 61ae229658a51ef01d55a09302983729 118 Gene3D G3DSA:1.10.1900.20 56 118 2.4E-29 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16445 61ae229658a51ef01d55a09302983729 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.5E-41 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16445 61ae229658a51ef01d55a09302983729 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.5E-41 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16445 61ae229658a51ef01d55a09302983729 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.5E-41 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_05470 0eeb105e9f3345c02d60738b7611fbc3 464 Pfam PF01554 MatE 22 182 4.2E-26 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_05470 0eeb105e9f3345c02d60738b7611fbc3 464 Pfam PF01554 MatE 247 407 7.2E-29 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_05470 0eeb105e9f3345c02d60738b7611fbc3 464 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 421 1.7E-65 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_05470 0eeb105e9f3345c02d60738b7611fbc3 464 PIRSF PIRSF006603 1 457 3.7E-85 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_09050 dd79e0326f51e7b3b6ecd0a3837416b9 749 SUPERFAMILY SSF51998 8 749 1.05E-287 T 14-10-2018 C2I25_09050 dd79e0326f51e7b3b6ecd0a3837416b9 749 PIRSF PIRSF000379 8 749 0.0 T 14-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 C2I25_09050 dd79e0326f51e7b3b6ecd0a3837416b9 749 Gene3D G3DSA:3.20.70.20 2 749 0.0 T 14-10-2018 C2I25_09050 dd79e0326f51e7b3b6ecd0a3837416b9 749 Pfam PF02901 Pyruvate formate lyase-like 24 608 2.2E-209 T 14-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 C2I25_09050 dd79e0326f51e7b3b6ecd0a3837416b9 749 Pfam PF01228 Glycine radical 624 730 3.8E-44 T 14-10-2018 IPR001150 Glycine radical domain GO:0003824 C2I25_09050 dd79e0326f51e7b3b6ecd0a3837416b9 749 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 11 749 0.0 T 14-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 C2I25_09050 dd79e0326f51e7b3b6ecd0a3837416b9 749 ProSitePatterns PS00850 Glycine radical domain signature. 719 727 - T 14-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site C2I25_12135 925fc663adabcc82c83cd95ad8047336 409 Gene3D G3DSA:1.10.3080.10 1 401 1.3E-30 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 C2I25_12135 925fc663adabcc82c83cd95ad8047336 409 SUPERFAMILY SSF81340 8 399 2.62E-50 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 C2I25_12135 925fc663adabcc82c83cd95ad8047336 409 Pfam PF00654 Voltage gated chloride channel 62 398 4.8E-40 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 C2I25_21595 f12ae10c0a3833a77a5b89c1eaba04cd 197 SUPERFAMILY SSF46689 5 84 2.64E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_21595 f12ae10c0a3833a77a5b89c1eaba04cd 197 Gene3D G3DSA:1.10.357.10 4 193 3.0E-28 T 14-10-2018 C2I25_21595 f12ae10c0a3833a77a5b89c1eaba04cd 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 2.9E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_21595 f12ae10c0a3833a77a5b89c1eaba04cd 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.5E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_21595 f12ae10c0a3833a77a5b89c1eaba04cd 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.5E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_07290 27b09862e90c78c29725e5e99cbcfedf 259 SUPERFAMILY SSF158430 4 123 1.11E-35 T 14-10-2018 C2I25_07290 27b09862e90c78c29725e5e99cbcfedf 259 SUPERFAMILY SSF158430 125 258 7.72E-42 T 14-10-2018 C2I25_07290 27b09862e90c78c29725e5e99cbcfedf 259 Pfam PF11155 Domain of unknown function (DUF2935) 8 114 1.4E-20 T 14-10-2018 IPR021328 Protein of unknown function DUF2935 C2I25_07290 27b09862e90c78c29725e5e99cbcfedf 259 Pfam PF11155 Domain of unknown function (DUF2935) 127 245 1.8E-26 T 14-10-2018 IPR021328 Protein of unknown function DUF2935 C2I25_07290 27b09862e90c78c29725e5e99cbcfedf 259 Gene3D G3DSA:1.20.1260.120 1 259 3.1E-103 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 7 115 2.3E-42 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 SUPERFAMILY SSF52440 4 118 4.82E-44 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Gene3D G3DSA:3.10.600.10 510 1062 2.5E-298 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Pfam PF00682 HMGL-like 535 807 1.2E-27 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 SUPERFAMILY SSF56059 89 332 2.47E-68 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Pfam PF00364 Biotin-requiring enzyme 1080 1146 3.0E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 PIRSF PIRSF001594 2 1148 0.0 T 14-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Gene3D G3DSA:2.40.50.100 1071 1147 6.9E-26 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 159 173 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 SUPERFAMILY SSF89000 835 1012 9.42E-60 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 347 454 3.2E-33 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Gene3D G3DSA:3.30.470.130 1 461 4.6E-194 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 121 327 1.1E-79 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 9 1146 0.0 T 14-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 SUPERFAMILY SSF51230 1072 1146 8.64E-23 T 14-10-2018 IPR011053 Single hybrid motif C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 SMART SM00878 347 454 7.3E-52 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Gene3D G3DSA:1.10.472.90 820 944 2.5E-298 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Gene3D G3DSA:3.20.20.70 515 819 2.5E-298 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 SUPERFAMILY SSF51569 527 838 4.76E-86 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Gene3D G3DSA:3.10.600.10 464 509 1.2E-5 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Gene3D G3DSA:1.10.10.2790 945 980 2.5E-298 T 14-10-2018 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 SUPERFAMILY SSF51246 342 460 1.94E-37 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I25_19760 054fc824a14a26a74d05f152bc65d938 1148 Pfam PF02436 Conserved carboxylase domain 830 1030 6.3E-77 T 14-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 C2I25_01025 0480bdd5f9354220cb5f4a04ff49fea1 337 Pfam PF00899 ThiF family 5 240 1.2E-62 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I25_01025 0480bdd5f9354220cb5f4a04ff49fea1 337 Gene3D G3DSA:3.40.50.720 1 249 2.8E-75 T 14-10-2018 C2I25_01025 0480bdd5f9354220cb5f4a04ff49fea1 337 SUPERFAMILY SSF69572 3 328 5.36E-87 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 SUPERFAMILY SSF116726 255 330 3.27E-20 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 Pfam PF02254 TrkA-N domain 114 226 9.8E-33 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 Gene3D G3DSA:1.10.287.70 2 112 9.4E-24 T 14-10-2018 C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 Gene3D G3DSA:3.30.70.1450 257 333 1.5E-19 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 SUPERFAMILY SSF51735 110 248 3.27E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 Gene3D G3DSA:3.40.50.720 113 256 7.8E-39 T 14-10-2018 C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 Pfam PF07885 Ion channel 16 90 1.1E-15 T 14-10-2018 IPR013099 Potassium channel domain C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 Pfam PF02080 TrkA-C domain 261 330 9.1E-15 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I25_12200 0be54a9c4213de3ff9cd6ea1247af27d 334 SUPERFAMILY SSF81324 7 132 5.23E-28 T 14-10-2018 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 Pfam PF08245 Mur ligase middle domain 106 311 2.0E-56 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 417 1.1E-22 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 SUPERFAMILY SSF63418 1 97 1.11E-25 T 14-10-2018 IPR035911 MurE/MurF, N-terminal C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 Gene3D G3DSA:3.40.1190.10 97 336 2.2E-90 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 Gene3D G3DSA:3.40.1390.10 3 96 5.3E-27 T 14-10-2018 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 483 1.1E-171 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 Pfam PF01225 Mur ligase family, catalytic domain 22 93 1.1E-13 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 483 36.768 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 SUPERFAMILY SSF53244 332 486 1.7E-50 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 Gene3D G3DSA:3.90.190.20 337 491 1.2E-60 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_19925 76babebfacd72a757dd7eee946f8bd86 491 SUPERFAMILY SSF53623 97 331 3.4E-76 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_07970 ec1dc688af58023107b06a57275aa12d 468 Pfam PF00324 Amino acid permease 18 456 4.3E-128 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I25_07970 ec1dc688af58023107b06a57275aa12d 468 PIRSF PIRSF006060 1 468 2.8E-84 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_07970 ec1dc688af58023107b06a57275aa12d 468 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I25_07970 ec1dc688af58023107b06a57275aa12d 468 Gene3D G3DSA:1.20.1740.10 9 467 4.7E-68 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 Gene3D G3DSA:3.50.50.60 5 325 3.2E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 9.4E-66 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 Gene3D G3DSA:3.30.390.30 339 459 7.3E-39 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 Gene3D G3DSA:3.50.50.60 146 265 3.2E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 SUPERFAMILY SSF51905 4 366 4.49E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 458 3.9E-167 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 448 4.0E-32 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PIRSF PIRSF000350 1 455 7.3E-87 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 SUPERFAMILY SSF55424 336 458 3.09E-37 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.9E-37 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 1.9E-37 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.9E-37 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 1.9E-37 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.9E-37 T 14-10-2018 C2I25_25715 475e2f0e74cfb0c198469f5247ffa7dd 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 321 5.8E-66 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_25890 1603f78593ab7f36dbd17a502371a269 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.1E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_25890 1603f78593ab7f36dbd17a502371a269 477 SUPERFAMILY SSF53383 86 473 1.1E-88 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_25890 1603f78593ab7f36dbd17a502371a269 477 SUPERFAMILY SSF46785 7 78 3.67E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_25890 1603f78593ab7f36dbd17a502371a269 477 Pfam PF00155 Aminotransferase class I and II 145 468 3.2E-34 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_25890 1603f78593ab7f36dbd17a502371a269 477 Gene3D G3DSA:3.90.1150.10 109 472 3.0E-97 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_25890 1603f78593ab7f36dbd17a502371a269 477 SMART SM00345 17 76 1.8E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_25890 1603f78593ab7f36dbd17a502371a269 477 Gene3D G3DSA:1.10.10.10 4 77 1.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25890 1603f78593ab7f36dbd17a502371a269 477 Gene3D G3DSA:3.40.640.10 147 368 3.0E-97 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 9.0E-70 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 SUPERFAMILY SSF55973 125 246 6.28E-53 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 2.2E-185 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 Gene3D G3DSA:3.30.300.10 13 284 3.8E-181 T 14-10-2018 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 PIRSF PIRSF000497 1 398 1.8E-177 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 SUPERFAMILY SSF55973 247 397 3.34E-70 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 SUPERFAMILY SSF55973 5 111 2.28E-47 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 1.1E-49 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 Gene3D G3DSA:3.30.300.10 104 389 3.8E-181 T 14-10-2018 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 58.755 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 Gene3D G3DSA:3.30.300.10 7 247 3.8E-181 T 14-10-2018 C2I25_15415 7d47a5697a63643f199938e815aebb01 399 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 7.2E-44 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I25_12235 da307adea1ec60b14061946319cf9c07 323 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 319 1.5E-128 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I25_12235 da307adea1ec60b14061946319cf9c07 323 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 1.0E-126 T 14-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I25_12235 da307adea1ec60b14061946319cf9c07 323 SUPERFAMILY SSF53659 5 322 4.52E-93 T 14-10-2018 C2I25_12235 da307adea1ec60b14061946319cf9c07 323 PIRSF PIRSF000428 1 323 2.2E-110 T 14-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I25_12235 da307adea1ec60b14061946319cf9c07 323 Gene3D G3DSA:3.40.50.10750 142 295 4.2E-134 T 14-10-2018 C2I25_12235 da307adea1ec60b14061946319cf9c07 323 Gene3D G3DSA:3.40.50.10950 19 319 4.2E-134 T 14-10-2018 C2I25_27730 002dde706cc276350a203d0ee3d84bde 101 Gene3D G3DSA:3.40.50.2300 1 101 7.3E-30 T 14-10-2018 C2I25_27730 002dde706cc276350a203d0ee3d84bde 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 1.4E-16 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I25_27730 002dde706cc276350a203d0ee3d84bde 101 SUPERFAMILY SSF52794 1 100 3.14E-27 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 SMART SM00245 184 375 1.7E-65 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 Gene3D G3DSA:1.10.101.10 380 464 9.0E-16 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 Gene3D G3DSA:2.30.42.10 111 198 4.9E-90 T 14-10-2018 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 SMART SM00228 111 182 9.9E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 Pfam PF03572 Peptidase family S41 212 374 8.6E-51 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 64 380 3.2E-120 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 Pfam PF13180 PDZ domain 112 184 2.0E-13 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 Pfam PF01471 Putative peptidoglycan binding domain 399 452 2.4E-15 T 14-10-2018 IPR002477 Peptidoglycan binding-like C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 SUPERFAMILY SSF50156 82 204 1.97E-21 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 Gene3D G3DSA:3.30.750.44 61 350 4.9E-90 T 14-10-2018 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 Gene3D G3DSA:3.90.226.10 199 372 4.9E-90 T 14-10-2018 C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 SUPERFAMILY SSF52096 48 379 1.7E-69 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_13320 064dcec36aaf3ef0f04411e5306bc44f 478 SUPERFAMILY SSF47090 384 454 1.02E-15 T 14-10-2018 IPR036365 PGBD-like superfamily C2I25_02920 bcb0ea4c0d29a61e97793d912c7405f2 341 SUPERFAMILY SSF53850 42 336 5.26E-69 T 14-10-2018 C2I25_02920 bcb0ea4c0d29a61e97793d912c7405f2 341 Gene3D G3DSA:3.40.190.10 45 310 5.8E-72 T 14-10-2018 C2I25_02920 bcb0ea4c0d29a61e97793d912c7405f2 341 PIRSF PIRSF002825 1 340 3.3E-61 T 14-10-2018 IPR026045 Ferric binding protein C2I25_02920 bcb0ea4c0d29a61e97793d912c7405f2 341 Pfam PF13343 Bacterial extracellular solute-binding protein 89 327 1.7E-40 T 14-10-2018 C2I25_02920 bcb0ea4c0d29a61e97793d912c7405f2 341 Gene3D G3DSA:3.40.190.10 144 323 5.8E-72 T 14-10-2018 C2I25_25925 57691c96e33257654811c77533d31e38 849 SMART SM00642 354 753 7.6E-8 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_25925 57691c96e33257654811c77533d31e38 849 Gene3D G3DSA:3.20.20.80 339 762 9.5E-180 T 14-10-2018 C2I25_25925 57691c96e33257654811c77533d31e38 849 Gene3D G3DSA:2.60.40.10 230 338 1.1E-29 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_25925 57691c96e33257654811c77533d31e38 849 SUPERFAMILY SSF49452 40 134 1.31E-26 T 14-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 C2I25_25925 57691c96e33257654811c77533d31e38 849 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 228 826 5.8E-278 T 14-10-2018 IPR011840 Pullulanase, type I C2I25_25925 57691c96e33257654811c77533d31e38 849 Pfam PF00128 Alpha amylase, catalytic domain 390 485 6.1E-10 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_25925 57691c96e33257654811c77533d31e38 849 Pfam PF00128 Alpha amylase, catalytic domain 517 714 3.3E-5 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_25925 57691c96e33257654811c77533d31e38 849 Gene3D G3DSA:2.60.40.1110 38 135 4.9E-27 T 14-10-2018 C2I25_25925 57691c96e33257654811c77533d31e38 849 SUPERFAMILY SSF51445 336 760 1.11E-127 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_25925 57691c96e33257654811c77533d31e38 849 Gene3D G3DSA:2.60.40.2320 141 229 3.1E-5 T 14-10-2018 C2I25_25925 57691c96e33257654811c77533d31e38 849 Pfam PF03714 Bacterial pullanase-associated domain 42 132 4.7E-22 T 14-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 C2I25_25925 57691c96e33257654811c77533d31e38 849 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 239 316 2.1E-13 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I25_25925 57691c96e33257654811c77533d31e38 849 Gene3D G3DSA:2.60.40.1180 763 848 1.4E-19 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_25925 57691c96e33257654811c77533d31e38 849 PIRSF PIRSF000463 641 834 1.3 T 14-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I25_25925 57691c96e33257654811c77533d31e38 849 PIRSF PIRSF000463 128 550 1.7E-31 T 14-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I25_25925 57691c96e33257654811c77533d31e38 849 SUPERFAMILY SSF81296 232 337 2.4E-20 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_05270 8382cd4e7508ecbb6985bdb2a73d1104 688 Gene3D G3DSA:3.40.50.300 319 674 9.8E-73 T 14-10-2018 C2I25_05270 8382cd4e7508ecbb6985bdb2a73d1104 688 Pfam PF13361 UvrD-like helicase C-terminal domain 314 659 7.6E-44 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 C2I25_05270 8382cd4e7508ecbb6985bdb2a73d1104 688 Gene3D G3DSA:3.40.50.300 51 309 1.5E-79 T 14-10-2018 C2I25_05270 8382cd4e7508ecbb6985bdb2a73d1104 688 SUPERFAMILY SSF52540 45 682 1.75E-129 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05270 8382cd4e7508ecbb6985bdb2a73d1104 688 Gene3D G3DSA:1.10.486.10 421 578 9.8E-73 T 14-10-2018 C2I25_05270 8382cd4e7508ecbb6985bdb2a73d1104 688 Pfam PF00580 UvrD/REP helicase N-terminal domain 156 309 7.6E-35 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 C2I25_05270 8382cd4e7508ecbb6985bdb2a73d1104 688 Gene3D G3DSA:1.10.10.160 150 226 1.5E-79 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily C2I25_00480 d6ca8f7a0e98093435efda1ad2b0b5d7 367 Pfam PF07786 Protein of unknown function (DUF1624) 12 213 3.4E-18 T 14-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 C2I25_03985 a46a3ddeacdaefebb597d775d2a5c981 353 PIRSF PIRSF021350 1 353 1.0E-136 T 14-10-2018 IPR008308 Uncharacterised conserved protein UCP021350 C2I25_03985 a46a3ddeacdaefebb597d775d2a5c981 353 Pfam PF14493 Helix-turn-helix domain 257 344 3.2E-23 T 14-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 Pfam PF03466 LysR substrate binding domain 89 289 4.9E-45 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 5.9E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 SUPERFAMILY SSF46785 1 111 7.72E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 Gene3D G3DSA:3.40.190.290 91 296 5.2E-44 T 14-10-2018 C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 Gene3D G3DSA:1.10.10.10 1 90 1.6E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 SUPERFAMILY SSF53850 90 294 2.72E-44 T 14-10-2018 C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_13355 162bf4a988ebc93c06e7774fcefc4e05 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_11220 adddaa9b39d8ad1415c4ae2fb52c447e 332 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I25_11220 adddaa9b39d8ad1415c4ae2fb52c447e 332 SUPERFAMILY SSF51395 11 322 4.76E-90 T 14-10-2018 C2I25_11220 adddaa9b39d8ad1415c4ae2fb52c447e 332 Gene3D G3DSA:1.10.1200.80 254 330 7.9E-19 T 14-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 C2I25_11220 adddaa9b39d8ad1415c4ae2fb52c447e 332 Pfam PF01207 Dihydrouridine synthase (Dus) 14 319 1.3E-110 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I25_11220 adddaa9b39d8ad1415c4ae2fb52c447e 332 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 322 1.5E-134 T 14-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 C2I25_11220 adddaa9b39d8ad1415c4ae2fb52c447e 332 Gene3D G3DSA:3.20.20.70 7 250 4.4E-81 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_11220 adddaa9b39d8ad1415c4ae2fb52c447e 332 PIRSF PIRSF006621 1 330 1.4E-106 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I25_07105 3cc876f089ee42d87b5d590b3457da0d 361 Pfam PF12294 Protein of unknown function (DUF3626) 55 355 2.7E-147 T 14-10-2018 IPR022074 Protein of unknown function DUF3626 C2I25_13590 0315ade4a361f824ac72c94765610b97 155 SUPERFAMILY SSF74982 4 132 4.45E-55 T 14-10-2018 IPR023620 Small protein B C2I25_13590 0315ade4a361f824ac72c94765610b97 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 2.0E-60 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 C2I25_13590 0315ade4a361f824ac72c94765610b97 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 8 149 7.1E-62 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 C2I25_13590 0315ade4a361f824ac72c94765610b97 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site C2I25_13590 0315ade4a361f824ac72c94765610b97 155 Gene3D G3DSA:2.40.280.10 3 129 3.5E-53 T 14-10-2018 IPR023620 Small protein B C2I25_13590 0315ade4a361f824ac72c94765610b97 155 Pfam PF01668 SmpB protein 9 150 1.6E-64 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 C2I25_13590 0315ade4a361f824ac72c94765610b97 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 78.148 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 C2I25_20230 c5bb05c8e5222a90a0a60a9ed1d3b526 558 SMART SM01121 240 558 2.6E-186 T 14-10-2018 IPR033470 Uncharacterised protein, DhaK domain C2I25_20230 c5bb05c8e5222a90a0a60a9ed1d3b526 558 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 558 6.3E-210 T 14-10-2018 IPR019986 DAK2 domain-containing protein YloV C2I25_20230 c5bb05c8e5222a90a0a60a9ed1d3b526 558 Gene3D G3DSA:1.25.40.340 6 175 1.4E-10 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_20230 c5bb05c8e5222a90a0a60a9ed1d3b526 558 Pfam PF02734 DAK2 domain 36 200 2.9E-40 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_20230 c5bb05c8e5222a90a0a60a9ed1d3b526 558 SUPERFAMILY SSF101473 2 200 1.57E-44 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_20230 c5bb05c8e5222a90a0a60a9ed1d3b526 558 SMART SM01120 36 201 1.8E-68 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_20230 c5bb05c8e5222a90a0a60a9ed1d3b526 558 Pfam PF13684 Dihydroxyacetone kinase family 240 558 9.0E-123 T 14-10-2018 IPR033470 Uncharacterised protein, DhaK domain C2I25_24115 4f0fc3da4f150b894d2630050bd49dc1 171 Gene3D G3DSA:1.20.1260.10 1 157 4.2E-62 T 14-10-2018 IPR012347 Ferritin-like C2I25_24115 4f0fc3da4f150b894d2630050bd49dc1 171 Pfam PF11553 Protein of unknown function (DUF3231) 2 167 2.0E-45 T 14-10-2018 IPR021617 Protein of unknown function DUF3231 C2I25_24535 914f78a1ec8176e52fe26c96ff58d4bc 227 PIRSF PIRSF033101 1 227 2.1E-70 T 14-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 C2I25_24535 914f78a1ec8176e52fe26c96ff58d4bc 227 Pfam PF10086 Putative membrane peptidase family (DUF2324) 12 136 5.2E-28 T 14-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 C2I25_24535 914f78a1ec8176e52fe26c96ff58d4bc 227 Pfam PF10086 Putative membrane peptidase family (DUF2324) 139 204 3.5E-11 T 14-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 402 563 1.3E-49 T 14-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 Gene3D G3DSA:3.10.170.10 244 402 2.3E-37 T 14-10-2018 C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 81 129 1.6E-13 T 14-10-2018 IPR011096 FTP domain C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 480 496 1.4E-18 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 411 422 1.4E-18 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 390 406 1.4E-18 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 361 381 1.4E-18 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 245 398 4.4E-34 T 14-10-2018 IPR013856 Peptidase M4 domain GO:0004222 C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 Pfam PF03413 Peptidase propeptide and YPEB domain 146 216 2.2E-5 T 14-10-2018 IPR025711 PepSY domain C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 Gene3D G3DSA:1.10.390.10 404 565 3.7E-47 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily C2I25_22870 d63d749aeaf4b32dbb8215def1d3d487 565 SUPERFAMILY SSF55486 244 562 2.75E-69 T 14-10-2018 C2I25_03525 7038dbb85a14b2bc0497603a5653e8df 152 Pfam PF00583 Acetyltransferase (GNAT) family 33 116 8.9E-15 T 14-10-2018 IPR000182 GNAT domain C2I25_03525 7038dbb85a14b2bc0497603a5653e8df 152 SUPERFAMILY SSF55729 17 151 1.42E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_03525 7038dbb85a14b2bc0497603a5653e8df 152 Gene3D G3DSA:3.40.630.30 1 152 2.1E-47 T 14-10-2018 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 Gene3D G3DSA:3.40.50.1970 457 649 3.0E-64 T 14-10-2018 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 SUPERFAMILY SSF53720 16 460 7.59E-80 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 Pfam PF00171 Aldehyde dehydrogenase family 13 407 8.0E-23 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 Gene3D G3DSA:3.40.605.10 19 451 9.2E-182 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 Gene3D G3DSA:3.40.309.10 227 412 9.2E-182 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 638 666 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 PIRSF PIRSF000111 1 867 0.0 T 14-10-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 Pfam PF00465 Iron-containing alcohol dehydrogenase 464 851 2.2E-121 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 SUPERFAMILY SSF56796 455 866 6.28E-127 T 14-10-2018 C2I25_17420 0ffb4b0973a4df2bce42cf0f78e1b144 867 Gene3D G3DSA:1.20.1090.10 651 867 1.8E-72 T 14-10-2018 C2I25_21220 a755d8c6811c0c2c5c0930d6e7414f81 146 Gene3D G3DSA:3.40.1510.10 2 146 7.7E-63 T 14-10-2018 IPR036482 Hut operon regulatory protein HutP superfamily C2I25_21220 a755d8c6811c0c2c5c0930d6e7414f81 146 Hamap MF_00779 Hut operon positive regulatory protein [hutP]. 1 146 45.628 T 14-10-2018 IPR023552 Hut operon regulatory protein HutP, bacillales C2I25_21220 a755d8c6811c0c2c5c0930d6e7414f81 146 SUPERFAMILY SSF111064 7 146 1.31E-62 T 14-10-2018 IPR036482 Hut operon regulatory protein HutP superfamily C2I25_21220 a755d8c6811c0c2c5c0930d6e7414f81 146 Pfam PF09021 HutP 9 144 3.0E-38 T 14-10-2018 IPR015111 Hut operon regulatory protein HutP C2I25_26745 30e2df138cf57019e1fe14b987bc66d5 369 SUPERFAMILY SSF56349 63 360 2.27E-72 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_26745 30e2df138cf57019e1fe14b987bc66d5 369 Pfam PF00589 Phage integrase family 172 352 9.3E-31 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_26745 30e2df138cf57019e1fe14b987bc66d5 369 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 64 118 2.6E-10 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I25_26745 30e2df138cf57019e1fe14b987bc66d5 369 Gene3D G3DSA:1.10.443.10 166 365 2.9E-58 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_26745 30e2df138cf57019e1fe14b987bc66d5 369 Pfam PF14657 Arm DNA-binding domain 14 56 2.5E-10 T 14-10-2018 IPR028259 AP2-like integrase, N-terminal domain C2I25_26745 30e2df138cf57019e1fe14b987bc66d5 369 Gene3D G3DSA:1.10.150.130 58 165 2.6E-25 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 SUPERFAMILY SSF55031 211 322 2.2E-38 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 PIRSF PIRSF037215 1 410 8.2E-194 T 14-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 58.329 T 14-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 Gene3D G3DSA:3.40.630.10 5 402 8.9E-186 T 14-10-2018 C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 SUPERFAMILY SSF53187 3 406 1.8E-82 T 14-10-2018 C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 Pfam PF01546 Peptidase family M20/M25/M40 141 404 3.0E-12 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 Gene3D G3DSA:3.30.70.360 211 321 8.9E-186 T 14-10-2018 C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 Pfam PF07687 Peptidase dimerisation domain 209 308 1.2E-11 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_20810 5e47771f003c55ed8631fa07156aa33d 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 410 6.5E-201 T 14-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 C2I25_10620 e82a9312ffc2428131bd721c1f2b06e0 302 SMART SM00829 10 299 1.9E-10 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_10620 e82a9312ffc2428131bd721c1f2b06e0 302 SUPERFAMILY SSF51735 127 276 1.13E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_10620 e82a9312ffc2428131bd721c1f2b06e0 302 Gene3D G3DSA:3.90.180.10 14 297 2.3E-89 T 14-10-2018 C2I25_10620 e82a9312ffc2428131bd721c1f2b06e0 302 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 99 3.5E-6 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_10620 e82a9312ffc2428131bd721c1f2b06e0 302 Gene3D G3DSA:3.40.50.720 145 251 2.3E-89 T 14-10-2018 C2I25_10620 e82a9312ffc2428131bd721c1f2b06e0 302 Pfam PF00107 Zinc-binding dehydrogenase 166 259 1.1E-13 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_10620 e82a9312ffc2428131bd721c1f2b06e0 302 SUPERFAMILY SSF50129 1 161 8.67E-30 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_16575 2050026dd4ab9d0330242d7c5e96a6bd 237 SMART SM00725 32 153 9.4E-47 T 14-10-2018 IPR006635 NEAT domain C2I25_16575 2050026dd4ab9d0330242d7c5e96a6bd 237 Gene3D G3DSA:2.60.40.1850 23 152 6.6E-46 T 14-10-2018 C2I25_16575 2050026dd4ab9d0330242d7c5e96a6bd 237 Pfam PF05031 Iron Transport-associated domain 31 146 1.2E-39 T 14-10-2018 IPR006635 NEAT domain C2I25_16575 2050026dd4ab9d0330242d7c5e96a6bd 237 TIGRFAM TIGR03656 IsdC: heme uptake protein IsdC 1 236 1.2E-98 T 14-10-2018 IPR019909 Haem uptake protein IsdC GO:0009274|GO:0015886|GO:0030492 C2I25_16575 2050026dd4ab9d0330242d7c5e96a6bd 237 SUPERFAMILY SSF158911 24 155 2.62E-43 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_16575 2050026dd4ab9d0330242d7c5e96a6bd 237 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 206 234 7.5E-15 T 14-10-2018 IPR017502 Sortase B cell surface sorting signal C2I25_16075 cb3ec99c385732c635136d3aab6da076 522 SUPERFAMILY SSF51338 4 519 4.32E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_16075 cb3ec99c385732c635136d3aab6da076 522 Pfam PF07969 Amidohydrolase family 48 518 1.2E-133 T 14-10-2018 IPR013108 Amidohydrolase 3 C2I25_16075 cb3ec99c385732c635136d3aab6da076 522 Gene3D G3DSA:3.10.310.70 77 196 2.0E-130 T 14-10-2018 C2I25_16075 cb3ec99c385732c635136d3aab6da076 522 Gene3D G3DSA:2.30.40.10 7 494 2.0E-130 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_16075 cb3ec99c385732c635136d3aab6da076 522 Gene3D G3DSA:3.20.20.140 59 477 2.0E-130 T 14-10-2018 C2I25_16075 cb3ec99c385732c635136d3aab6da076 522 SUPERFAMILY SSF51556 58 477 1.93E-35 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 SUPERFAMILY SSF82693 156 308 1.36E-10 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Pfam PF00873 AcrB/AcrD/AcrF family 5 992 1.2E-208 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 SUPERFAMILY SSF82714 688 770 2.35E-11 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Gene3D G3DSA:3.30.2090.10 686 774 2.9E-257 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 SUPERFAMILY SSF82866 286 483 1.01E-37 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Gene3D G3DSA:1.20.1640.10 11 492 2.9E-257 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Gene3D G3DSA:3.30.2090.10 177 262 2.9E-257 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Gene3D G3DSA:3.30.70.1320 133 319 2.9E-257 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Gene3D G3DSA:1.20.1640.10 493 989 2.9E-257 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 SUPERFAMILY SSF82714 183 258 1.12E-8 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.3E-35 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 431 454 1.3E-35 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.3E-35 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 323 346 1.3E-35 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 456 479 1.3E-35 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 378 402 1.3E-35 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 350 371 1.3E-35 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 SUPERFAMILY SSF82693 41 132 1.73E-17 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Gene3D G3DSA:3.30.70.1430 539 636 2.9E-257 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 SUPERFAMILY SSF82866 773 995 8.11E-48 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Gene3D G3DSA:3.30.70.1440 637 831 2.9E-257 T 14-10-2018 C2I25_07890 1280af92ea3dd107cc28ce554d85afdc 1014 Gene3D G3DSA:3.30.70.1430 41 782 2.9E-257 T 14-10-2018 C2I25_07920 636df3dfcaf912f622764d1984e51eb1 240 Pfam PF02421 Ferrous iron transport protein B 5 157 1.4E-60 T 14-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 C2I25_07920 636df3dfcaf912f622764d1984e51eb1 240 SUPERFAMILY SSF52540 5 210 5.32E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07920 636df3dfcaf912f622764d1984e51eb1 240 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 7.9E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_07920 636df3dfcaf912f622764d1984e51eb1 240 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 54 69 7.9E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_07920 636df3dfcaf912f622764d1984e51eb1 240 Gene3D G3DSA:3.40.50.300 2 193 1.4E-43 T 14-10-2018 C2I25_24440 3c6411273ac0bbe3d67dee32039dcef4 388 SUPERFAMILY SSF56601 52 377 3.42E-81 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_24440 3c6411273ac0bbe3d67dee32039dcef4 388 Gene3D G3DSA:3.40.710.10 45 388 4.5E-128 T 14-10-2018 C2I25_24440 3c6411273ac0bbe3d67dee32039dcef4 388 Pfam PF00144 Beta-lactamase 60 371 2.3E-67 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_14290 59db1db68c4c6500bf30f92f2971be01 323 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 322 1.1E-128 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I25_14290 59db1db68c4c6500bf30f92f2971be01 323 Gene3D G3DSA:3.30.540.10 7 311 2.0E-134 T 14-10-2018 C2I25_14290 59db1db68c4c6500bf30f92f2971be01 323 PIRSF PIRSF004532 1 322 2.8E-150 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I25_14290 59db1db68c4c6500bf30f92f2971be01 323 SUPERFAMILY SSF56655 2 314 6.41E-106 T 14-10-2018 C2I25_14290 59db1db68c4c6500bf30f92f2971be01 323 Gene3D G3DSA:3.40.190.90 122 284 2.0E-134 T 14-10-2018 C2I25_14290 59db1db68c4c6500bf30f92f2971be01 323 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 311 3.3E-142 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I25_23000 3e130aa0ce6f63e645ac91d23605f67a 442 SUPERFAMILY SSF56176 352 437 3.82E-19 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_23000 3e130aa0ce6f63e645ac91d23605f67a 442 Pfam PF00571 CBS domain 288 338 5.1E-7 T 14-10-2018 IPR000644 CBS domain C2I25_23000 3e130aa0ce6f63e645ac91d23605f67a 442 SMART SM01091 354 431 2.5E-22 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_23000 3e130aa0ce6f63e645ac91d23605f67a 442 Gene3D G3DSA:3.10.580.10 195 347 1.0E-50 T 14-10-2018 C2I25_23000 3e130aa0ce6f63e645ac91d23605f67a 442 Gene3D G3DSA:3.30.465.10 348 439 2.5E-19 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_23000 3e130aa0ce6f63e645ac91d23605f67a 442 Pfam PF03471 Transporter associated domain 356 429 1.2E-18 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_23000 3e130aa0ce6f63e645ac91d23605f67a 442 Pfam PF01595 Domain of unknown function DUF21 9 201 2.5E-50 T 14-10-2018 IPR002550 CNNM, transmembrane domain C2I25_23000 3e130aa0ce6f63e645ac91d23605f67a 442 SUPERFAMILY SSF54631 204 341 1.52E-30 T 14-10-2018 C2I25_23355 28a16306d0b8a5750a36fceffdf12c5e 399 Gene3D G3DSA:1.20.1250.20 6 380 4.7E-62 T 14-10-2018 C2I25_23355 28a16306d0b8a5750a36fceffdf12c5e 399 Pfam PF07690 Major Facilitator Superfamily 15 347 5.8E-59 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_23355 28a16306d0b8a5750a36fceffdf12c5e 399 SUPERFAMILY SSF103473 1 391 2.09E-70 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_16470 13728a398c94c3ee3bdef6c8660b3beb 599 Gene3D G3DSA:1.20.1720.10 99 303 9.4E-44 T 14-10-2018 C2I25_16470 13728a398c94c3ee3bdef6c8660b3beb 599 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 100 587 1.7E-137 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_16470 13728a398c94c3ee3bdef6c8660b3beb 599 Pfam PF07690 Major Facilitator Superfamily 103 494 2.6E-53 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_16470 13728a398c94c3ee3bdef6c8660b3beb 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 387 411 9.6E-12 T 14-10-2018 C2I25_16470 13728a398c94c3ee3bdef6c8660b3beb 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 102 126 9.6E-12 T 14-10-2018 C2I25_16470 13728a398c94c3ee3bdef6c8660b3beb 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 193 213 9.6E-12 T 14-10-2018 C2I25_16470 13728a398c94c3ee3bdef6c8660b3beb 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 223 247 9.6E-12 T 14-10-2018 C2I25_16470 13728a398c94c3ee3bdef6c8660b3beb 599 SUPERFAMILY SSF103473 87 593 2.22E-68 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_27735 1b6234869bedf6b47bc0cc48121fe710 519 SUPERFAMILY SSF51445 66 327 6.78E-23 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_27735 1b6234869bedf6b47bc0cc48121fe710 519 Gene3D G3DSA:3.20.20.70 53 239 2.3E-6 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_27735 1b6234869bedf6b47bc0cc48121fe710 519 Pfam PF02638 Glycosyl hydrolase-like 10 39 359 1.1E-108 T 14-10-2018 IPR003790 Glycosyl hydrolase-like 10 C2I25_27735 1b6234869bedf6b47bc0cc48121fe710 519 Gene3D G3DSA:2.60.40.10 420 519 1.2E-9 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_23755 6386903e53a56a84f01bcce84e6ca96b 213 Pfam PF00005 ABC transporter 2 137 2.5E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_23755 6386903e53a56a84f01bcce84e6ca96b 213 SUPERFAMILY SSF52540 1 197 3.44E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23755 6386903e53a56a84f01bcce84e6ca96b 213 Gene3D G3DSA:3.40.50.300 1 212 1.3E-44 T 14-10-2018 C2I25_23755 6386903e53a56a84f01bcce84e6ca96b 213 SMART SM00382 11 186 6.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_22925 c8d4fef4a743708c3b2dcc26bf366c4b 222 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 219 1.4E-81 T 14-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I25_22925 c8d4fef4a743708c3b2dcc26bf366c4b 222 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 216 4.5E-57 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I25_22925 c8d4fef4a743708c3b2dcc26bf366c4b 222 Gene3D G3DSA:3.20.20.70 1 221 2.1E-85 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_22925 c8d4fef4a743708c3b2dcc26bf366c4b 222 SUPERFAMILY SSF51569 1 219 4.5E-74 T 14-10-2018 C2I25_22925 c8d4fef4a743708c3b2dcc26bf366c4b 222 Hamap MF_00494 Probable transaldolase [tal]. 1 221 45.62 T 14-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I25_22925 c8d4fef4a743708c3b2dcc26bf366c4b 222 ProSitePatterns PS00958 Transaldolase active site. 87 104 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I25_22925 c8d4fef4a743708c3b2dcc26bf366c4b 222 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.2E-7 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.2E-7 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.3E-13 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.3E-13 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.3E-13 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.2E-88 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 SUPERFAMILY SSF52317 1 187 1.53E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 Pfam PF00117 Glutamine amidotransferase class-I 4 186 3.5E-55 T 14-10-2018 IPR017926 Glutamine amidotransferase C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 Gene3D G3DSA:3.40.50.880 1 188 2.5E-64 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 8.0E-36 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 8.0E-36 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 8.0E-36 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 8.0E-36 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 8.0E-36 T 14-10-2018 C2I25_11250 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 164 177 8.0E-36 T 14-10-2018 C2I25_13885 7ee282fd399ad00f97b2e7f6ec851bad 272 Gene3D G3DSA:3.40.50.150 41 264 1.2E-27 T 14-10-2018 C2I25_13885 7ee282fd399ad00f97b2e7f6ec851bad 272 SUPERFAMILY SSF53335 19 241 5.22E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_13885 7ee282fd399ad00f97b2e7f6ec851bad 272 Pfam PF08241 Methyltransferase domain 66 155 5.9E-13 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 SMART SM00244 20 178 2.5E-58 T 14-10-2018 IPR001107 Band 7 domain C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 SUPERFAMILY SSF117892 51 185 3.53E-40 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 Pfam PF01145 SPFH domain / Band 7 family 24 194 4.3E-34 T 14-10-2018 IPR001107 Band 7 domain C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 27 49 1.1E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 75 96 1.1E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 154 172 1.1E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 110 127 1.1E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 130 153 1.1E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 173 194 1.1E-28 T 14-10-2018 IPR001972 Stomatin family GO:0016020 C2I25_01285 0242e7a9996cd620d0090201a7e5d25c 322 Gene3D G3DSA:3.30.479.30 48 180 2.3E-44 T 14-10-2018 C2I25_04075 d336143bc516f968cd059122ccce46ab 859 SUPERFAMILY SSF55729 656 833 1.36E-12 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_04075 d336143bc516f968cd059122ccce46ab 859 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 200 302 2.6E-16 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD C2I25_04075 d336143bc516f968cd059122ccce46ab 859 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 18 297 1.8E-17 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD C2I25_04075 d336143bc516f968cd059122ccce46ab 859 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 545 836 1.6E-93 T 14-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal C2I25_20820 477ff405619a7781f51122b42677a748 176 Gene3D G3DSA:1.10.10.10 89 174 2.0E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20820 477ff405619a7781f51122b42677a748 176 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 169 1.5E-34 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 C2I25_20820 477ff405619a7781f51122b42677a748 176 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 8 86 3.1E-8 T 14-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 C2I25_20820 477ff405619a7781f51122b42677a748 176 SUPERFAMILY SSF46767 89 172 5.23E-31 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 C2I25_20820 477ff405619a7781f51122b42677a748 176 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 92 171 7.6E-31 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 C2I25_20820 477ff405619a7781f51122b42677a748 176 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 C2I25_20820 477ff405619a7781f51122b42677a748 176 SUPERFAMILY SSF53155 8 86 6.08E-13 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 C2I25_03240 0486ff294018bd2d856ade0c7c4be2c8 62 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 3 61 9.3E-22 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I25_03240 0486ff294018bd2d856ade0c7c4be2c8 62 SUPERFAMILY SSF50182 3 61 5.11E-19 T 14-10-2018 IPR010920 LSM domain superfamily C2I25_03240 0486ff294018bd2d856ade0c7c4be2c8 62 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 62 25.134 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I25_03240 0486ff294018bd2d856ade0c7c4be2c8 62 Pfam PF17209 Hfq protein 4 61 1.7E-19 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I25_03240 0486ff294018bd2d856ade0c7c4be2c8 62 Gene3D G3DSA:2.30.30.100 1 62 2.0E-21 T 14-10-2018 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 Gene3D G3DSA:3.50.50.60 136 253 6.7E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 SUPERFAMILY SSF51905 3 268 4.96E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 Gene3D G3DSA:3.50.50.60 6 298 6.7E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 294 1.3E-101 T 14-10-2018 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.3E-14 T 14-10-2018 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 9.3E-14 T 14-10-2018 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 9.3E-14 T 14-10-2018 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 9.3E-14 T 14-10-2018 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 290 308 3.2E-16 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 132 3.2E-16 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 3.2E-16 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 159 183 3.2E-16 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_03930 6003cfe04f93a7ad2d90a1e785bc339c 326 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 323 9.3E-140 T 14-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA C2I25_27695 db6ad5f243a9f5b06c85635890661a62 333 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 311 7.4E-81 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_27695 db6ad5f243a9f5b06c85635890661a62 333 Gene3D G3DSA:3.40.50.1100 13 316 8.8E-126 T 14-10-2018 C2I25_27695 db6ad5f243a9f5b06c85635890661a62 333 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 27 325 3.1E-122 T 14-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 C2I25_27695 db6ad5f243a9f5b06c85635890661a62 333 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 48 61 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 C2I25_27695 db6ad5f243a9f5b06c85635890661a62 333 Gene3D G3DSA:3.40.50.1100 56 152 8.8E-126 T 14-10-2018 C2I25_27695 db6ad5f243a9f5b06c85635890661a62 333 SUPERFAMILY SSF53686 9 319 4.98E-98 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 895 982 3.9E-23 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 532 616 4.6E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 902 968 7.46E-10 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 347 441 1.5E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 1177 1241 2.12E-8 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 1170 1258 3.8E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 804 894 2.3E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 1077 1169 2.2E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 442 531 3.1E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 1085 1157 1.14E-8 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 721 792 1.22E-8 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 708 803 2.4E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 617 707 3.6E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 53 334 4.0E-22 T 14-10-2018 IPR026588 Choice-of-anchor A domain C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 632 696 6.28E-9 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 1269 1334 4.32E-9 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 813 877 3.61E-9 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 983 1076 1.4E-23 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 Gene3D G3DSA:2.60.40.10 1259 1358 1.4E-23 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 540 612 9.81E-9 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 352 422 1.57E-9 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 999 1063 1.14E-7 T 14-10-2018 C2I25_06980 3fcfe835f94a728a1ff6e12077c88919 1491 SUPERFAMILY SSF49478 448 516 2.39E-9 T 14-10-2018 C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 Pfam PF00176 SNF2 family N-terminal domain 470 735 8.2E-59 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 Gene3D G3DSA:1.20.120.850 689 912 7.3E-90 T 14-10-2018 C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 SMART SM00487 447 637 6.2E-31 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 Gene3D G3DSA:3.40.50.300 675 877 7.3E-90 T 14-10-2018 C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 SUPERFAMILY SSF52540 670 917 3.82E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 Gene3D G3DSA:3.40.50.10810 430 664 2.6E-71 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 SMART SM00490 780 863 2.3E-24 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 Pfam PF00271 Helicase conserved C-terminal domain 751 863 1.0E-22 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 SUPERFAMILY SSF52540 426 665 8.4E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12965 209e3860be33b61bd7b2714f7db7bf8f 918 Pfam PF12419 SNF2 Helicase protein 270 398 8.0E-34 T 14-10-2018 IPR022138 Helicase SWF/SNF-related C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 292 1.9E-118 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 Gene3D G3DSA:3.30.479.20 155 273 5.1E-42 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 Gene3D G3DSA:3.30.479.20 56 146 4.1E-23 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 Gene3D G3DSA:1.10.8.10 1 55 9.7E-29 T 14-10-2018 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 Gene3D G3DSA:1.10.286.20 193 239 5.1E-42 T 14-10-2018 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 SUPERFAMILY SSF46934 1 55 1.1E-21 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 SUPERFAMILY SSF54713 151 293 2.62E-52 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 Pfam PF00889 Elongation factor TS 70 274 8.3E-75 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 SUPERFAMILY SSF54713 55 144 4.91E-21 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 C2I25_20380 67be4f6ec89753fea0426bbf638b3141 295 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 82.601 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I25_22570 e93c0fdfd04273534da1470e85f73faa 207 Pfam PF01810 LysE type translocator 12 203 5.7E-35 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_22570 e93c0fdfd04273534da1470e85f73faa 207 PIRSF PIRSF006324 1 206 3.8E-48 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_06440 0bea8455caf09795bbc89295b71aef74 111 Gene3D G3DSA:3.30.750.24 1 110 8.4E-27 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_06440 0bea8455caf09795bbc89295b71aef74 111 SUPERFAMILY SSF52091 3 106 5.89E-25 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_06440 0bea8455caf09795bbc89295b71aef74 111 Pfam PF01740 STAS domain 14 101 9.3E-17 T 14-10-2018 IPR002645 STAS domain C2I25_06440 0bea8455caf09795bbc89295b71aef74 111 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 8.1E-29 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 C2I25_12375 aa020202d695d3de1a9f70fe14848f75 466 SUPERFAMILY SSF52025 127 227 8.5E-10 T 14-10-2018 C2I25_12375 aa020202d695d3de1a9f70fe14848f75 466 Pfam PF02225 PA domain 130 219 3.7E-10 T 14-10-2018 IPR003137 PA domain C2I25_12375 aa020202d695d3de1a9f70fe14848f75 466 Gene3D G3DSA:3.50.30.30 105 236 1.4E-99 T 14-10-2018 C2I25_12375 aa020202d695d3de1a9f70fe14848f75 466 Pfam PF04389 Peptidase family M28 246 446 3.0E-39 T 14-10-2018 IPR007484 Peptidase M28 C2I25_12375 aa020202d695d3de1a9f70fe14848f75 466 Gene3D G3DSA:3.40.630.10 64 444 1.4E-99 T 14-10-2018 C2I25_12375 aa020202d695d3de1a9f70fe14848f75 466 SUPERFAMILY SSF53187 39 452 1.4E-54 T 14-10-2018 C2I25_14590 3430be307ded4ac6d59d12b1f31253c0 444 PRINTS PR00758 Arsenical pump membrane protein signature 113 137 1.5E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_14590 3430be307ded4ac6d59d12b1f31253c0 444 PRINTS PR00758 Arsenical pump membrane protein signature 289 313 1.5E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_14590 3430be307ded4ac6d59d12b1f31253c0 444 PRINTS PR00758 Arsenical pump membrane protein signature 230 255 1.5E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_14590 3430be307ded4ac6d59d12b1f31253c0 444 PRINTS PR00758 Arsenical pump membrane protein signature 381 406 1.5E-10 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_14590 3430be307ded4ac6d59d12b1f31253c0 444 Pfam PF03600 Citrate transporter 27 385 2.3E-50 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 C2I25_27440 19ef2c718471a6d84f7d75801bb82216 219 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I25_27440 19ef2c718471a6d84f7d75801bb82216 219 Gene3D G3DSA:2.160.10.10 3 218 5.0E-67 T 14-10-2018 C2I25_27440 19ef2c718471a6d84f7d75801bb82216 219 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 8.0E-11 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_27440 19ef2c718471a6d84f7d75801bb82216 219 SUPERFAMILY SSF51161 31 212 1.66E-43 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 Gene3D G3DSA:2.40.500.20 183 302 7.7E-45 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 259 266 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 SUPERFAMILY SSF54719 182 296 9.95E-42 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 103 183 2.6E-28 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 Gene3D G3DSA:1.10.287.990 120 182 1.7E-24 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 SUPERFAMILY SSF46609 99 183 1.03E-31 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 190 292 1.5E-35 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 106 117 2.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 257 269 2.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 219 227 2.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 166 179 2.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_04060 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 127 140 2.0E-21 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_21055 3556ab143843a9f6fbf745698841dfb8 257 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_21055 3556ab143843a9f6fbf745698841dfb8 257 SMART SM00382 27 223 9.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_21055 3556ab143843a9f6fbf745698841dfb8 257 Pfam PF00005 ABC transporter 18 174 2.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21055 3556ab143843a9f6fbf745698841dfb8 257 SUPERFAMILY SSF52540 1 237 2.05E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21055 3556ab143843a9f6fbf745698841dfb8 257 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 243 7.2E-108 T 14-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 C2I25_21055 3556ab143843a9f6fbf745698841dfb8 257 Gene3D G3DSA:3.40.50.300 1 254 1.9E-61 T 14-10-2018 C2I25_26005 d6517fe4e576fe00270359135bd9f372 371 Gene3D G3DSA:3.30.9.10 88 311 7.4E-84 T 14-10-2018 C2I25_26005 d6517fe4e576fe00270359135bd9f372 371 SUPERFAMILY SSF51905 2 366 2.46E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_26005 d6517fe4e576fe00270359135bd9f372 371 Gene3D G3DSA:3.50.50.60 5 351 7.4E-84 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_26005 d6517fe4e576fe00270359135bd9f372 371 SUPERFAMILY SSF54373 224 311 4.45E-17 T 14-10-2018 C2I25_26005 d6517fe4e576fe00270359135bd9f372 371 Pfam PF01266 FAD dependent oxidoreductase 4 351 3.5E-55 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 52 66 9.2E-7 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 82 98 9.2E-7 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 11 25 9.2E-7 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 Pfam PF00117 Glutamine amidotransferase class-I 13 192 1.1E-45 T 14-10-2018 IPR017926 Glutamine amidotransferase C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 Gene3D G3DSA:3.30.300.10 396 515 1.7E-51 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 SUPERFAMILY SSF52317 6 230 2.21E-63 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 515 1.2E-157 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 11 197 1.7E-84 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 SUPERFAMILY SSF52402 190 408 5.95E-63 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 Pfam PF02540 NAD synthase 212 285 5.2E-6 T 14-10-2018 IPR022310 NAD/GMP synthase C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 Gene3D G3DSA:3.40.50.620 203 395 4.4E-76 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 Pfam PF00958 GMP synthase C terminal domain 423 514 1.8E-44 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00097 Anthranilate synthase component II signature 55 64 1.2E-5 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00097 Anthranilate synthase component II signature 170 183 1.2E-5 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00097 Anthranilate synthase component II signature 82 93 1.2E-5 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 8 515 55.601 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 55 64 6.8E-8 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 82 93 6.8E-8 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 170 183 6.8E-8 T 14-10-2018 C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 Gene3D G3DSA:3.40.50.880 7 202 5.9E-59 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_10100 c008a3552fab5a090c0d1f4f1b01463a 515 SUPERFAMILY SSF54810 395 515 4.05E-51 T 14-10-2018 C2I25_06180 b25abbc5738d1d156976426497900c59 144 ProSitePatterns PS00892 HIT domain signature. 90 108 - T 14-10-2018 IPR019808 Histidine triad, conserved site C2I25_06180 b25abbc5738d1d156976426497900c59 144 Gene3D G3DSA:1.20.5.1170 118 144 2.4E-21 T 14-10-2018 C2I25_06180 b25abbc5738d1d156976426497900c59 144 Pfam PF01230 HIT domain 16 110 9.0E-28 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_06180 b25abbc5738d1d156976426497900c59 144 SUPERFAMILY SSF54197 6 140 2.78E-47 T 14-10-2018 IPR036265 HIT-like superfamily C2I25_06180 b25abbc5738d1d156976426497900c59 144 Gene3D G3DSA:3.30.428.10 1 117 1.0E-40 T 14-10-2018 IPR036265 HIT-like superfamily C2I25_06180 b25abbc5738d1d156976426497900c59 144 PRINTS PR00332 Histidine triad family signature 97 107 1.9E-17 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_06180 b25abbc5738d1d156976426497900c59 144 PRINTS PR00332 Histidine triad family signature 30 48 1.9E-17 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_06180 b25abbc5738d1d156976426497900c59 144 PRINTS PR00332 Histidine triad family signature 9 25 1.9E-17 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_12240 1750a8d737319f15206f49462a023381 281 SUPERFAMILY SSF55681 7 266 1.08E-68 T 14-10-2018 C2I25_12240 1750a8d737319f15206f49462a023381 281 Pfam PF03099 Biotin/lipoate A/B protein ligase family 75 182 3.5E-13 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I25_12240 1750a8d737319f15206f49462a023381 281 Gene3D G3DSA:3.30.930.10 5 280 1.8E-78 T 14-10-2018 C2I25_12240 1750a8d737319f15206f49462a023381 281 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 6 278 51.335 T 14-10-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 MetaCyc: PWY-6987 C2I25_06185 9a0f1b50df53eabe94a48efbe8c5f35f 120 Pfam PF12732 YtxH-like protein 9 83 1.8E-10 T 14-10-2018 IPR024623 Uncharacterised protein family YtxH C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 Gene3D G3DSA:1.10.3370.10 1 426 3.8E-155 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 SUPERFAMILY SSF103491 1 421 9.02E-125 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PIRSF PIRSF004557 1 434 2.2E-124 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 Pfam PF00344 SecY translocase 68 414 7.5E-110 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 9.0E-97 T 14-10-2018 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 426 4.9E-143 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 430 28.527 T 14-10-2018 IPR026593 Protein translocase subunit SecY C2I25_25900 3fe3eaff1955b48edbd2eb17b56269f0 434 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I25_27990 ab1d023eff8bdd89615fe2bccf9fd2aa 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 7.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_27990 ab1d023eff8bdd89615fe2bccf9fd2aa 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 7.9E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_27990 ab1d023eff8bdd89615fe2bccf9fd2aa 209 SUPERFAMILY SSF46689 13 98 2.62E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_27990 ab1d023eff8bdd89615fe2bccf9fd2aa 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 9.2E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_27990 ab1d023eff8bdd89615fe2bccf9fd2aa 209 Gene3D G3DSA:1.10.357.10 70 208 1.4E-12 T 14-10-2018 C2I25_27990 ab1d023eff8bdd89615fe2bccf9fd2aa 209 SUPERFAMILY SSF48498 124 206 1.27E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_27990 ab1d023eff8bdd89615fe2bccf9fd2aa 209 Gene3D G3DSA:1.10.10.60 11 69 2.1E-16 T 14-10-2018 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 SUPERFAMILY SSF52540 4 414 5.87E-143 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Gene3D G3DSA:3.40.50.300 263 413 3.4E-54 T 14-10-2018 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Gene3D G3DSA:3.40.50.300 414 595 2.5E-53 T 14-10-2018 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Pfam PF00271 Helicase conserved C-terminal domain 440 544 6.0E-19 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 SUPERFAMILY SSF52540 32 593 3.38E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 SMART SM00487 9 425 1.3E-24 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Pfam PF02151 UvrB/uvrC motif 622 656 4.8E-9 T 14-10-2018 IPR001943 UVR domain GO:0005515 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 657 44.914 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 SMART SM00490 459 545 2.9E-20 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Gene3D G3DSA:3.40.50.300 1 243 3.4E-83 T 14-10-2018 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 655 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 SUPERFAMILY SSF46600 613 656 5.1E-10 T 14-10-2018 IPR036876 UVR domain superfamily C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Pfam PF04851 Type III restriction enzyme, res subunit 16 115 5.0E-10 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Gene3D G3DSA:4.10.860.10 606 657 9.2E-6 T 14-10-2018 C2I25_13390 a5756ca53bb8ce8b47cd809006279e18 658 Pfam PF12344 Ultra-violet resistance protein B 551 592 1.4E-22 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain C2I25_07020 a1404d0d9ecad1a066ea49a0670a9db6 140 Gene3D G3DSA:3.10.180.10 3 139 2.4E-54 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_07020 a1404d0d9ecad1a066ea49a0670a9db6 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 128 2.3E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_07020 a1404d0d9ecad1a066ea49a0670a9db6 140 SUPERFAMILY SSF54593 8 131 2.28E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 ProSitePatterns PS00501 Signal peptidases I serine active site. 36 43 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 Gene3D G3DSA:2.10.109.10 36 168 4.0E-34 T 14-10-2018 C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 SUPERFAMILY SSF51306 30 175 4.06E-44 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 ProSitePatterns PS00761 Signal peptidases I signature 3. 133 146 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 Pfam PF00717 Peptidase S24-like 34 102 1.7E-17 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 27 43 3.8E-15 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 3.8E-15 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 128 147 3.8E-15 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_26420 df1afe111c678bf513ba9a8b3cf3fd89 176 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 170 4.4E-51 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_01135 850dee136e4c019ed2fd5450d11aa095 562 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 334 345 - T 14-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I25_01135 850dee136e4c019ed2fd5450d11aa095 562 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 109 119 - T 14-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I25_01135 850dee136e4c019ed2fd5450d11aa095 562 Gene3D G3DSA:3.10.410.10 449 538 1.3E-36 T 14-10-2018 C2I25_01135 850dee136e4c019ed2fd5450d11aa095 562 SUPERFAMILY SSF52540 10 560 1.63E-249 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01135 850dee136e4c019ed2fd5450d11aa095 562 Gene3D G3DSA:3.30.1510.10 135 253 7.0E-208 T 14-10-2018 C2I25_01135 850dee136e4c019ed2fd5450d11aa095 562 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 562 49.357 T 14-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I25_01135 850dee136e4c019ed2fd5450d11aa095 562 Pfam PF01268 Formate--tetrahydrofolate ligase 8 562 1.6E-273 T 14-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I25_01135 850dee136e4c019ed2fd5450d11aa095 562 Gene3D G3DSA:3.40.50.300 12 444 7.0E-208 T 14-10-2018 C2I25_05830 9cd619e68185f802c3c23f946ee9043b 161 Pfam PF04542 Sigma-70 region 2 10 76 2.2E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_05830 9cd619e68185f802c3c23f946ee9043b 161 SUPERFAMILY SSF88659 103 155 3.18E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_05830 9cd619e68185f802c3c23f946ee9043b 161 Gene3D G3DSA:1.10.1740.10 1 78 7.1E-20 T 14-10-2018 C2I25_05830 9cd619e68185f802c3c23f946ee9043b 161 Gene3D G3DSA:1.10.10.10 102 160 3.6E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_05830 9cd619e68185f802c3c23f946ee9043b 161 Pfam PF08281 Sigma-70, region 4 107 154 5.8E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_05830 9cd619e68185f802c3c23f946ee9043b 161 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 7 159 2.5E-67 T 14-10-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_05830 9cd619e68185f802c3c23f946ee9043b 161 SUPERFAMILY SSF88946 5 94 1.57E-20 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_05830 9cd619e68185f802c3c23f946ee9043b 161 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 157 7.7E-24 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_03235 091fba9d12c0170293c751ce181fd6c1 200 Pfam PF13023 HD domain 12 169 1.3E-48 T 14-10-2018 IPR006674 HD domain C2I25_03235 091fba9d12c0170293c751ce181fd6c1 200 SUPERFAMILY SSF109604 3 175 2.67E-36 T 14-10-2018 C2I25_03235 091fba9d12c0170293c751ce181fd6c1 200 Gene3D G3DSA:1.10.3210.10 2 191 8.3E-48 T 14-10-2018 C2I25_08415 aefe1d426b216a52572fa16e00fd5c8b 322 Pfam PF01497 Periplasmic binding protein 62 296 1.4E-36 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_08415 aefe1d426b216a52572fa16e00fd5c8b 322 Gene3D G3DSA:3.40.50.1980 149 322 1.8E-72 T 14-10-2018 C2I25_08415 aefe1d426b216a52572fa16e00fd5c8b 322 SUPERFAMILY SSF53807 44 316 1.28E-71 T 14-10-2018 C2I25_08415 aefe1d426b216a52572fa16e00fd5c8b 322 Gene3D G3DSA:3.40.50.1980 42 148 1.2E-38 T 14-10-2018 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 SMART SM00839 197 426 3.0E-98 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 106 120 3.8E-30 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 228 248 3.8E-30 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 186 208 3.8E-30 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 3.8E-30 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 195 426 1.2E-79 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 SUPERFAMILY SSF51735 195 427 5.49E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 51 177 2.1E-54 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 Gene3D G3DSA:3.40.50.720 195 428 5.8E-88 T 14-10-2018 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 SUPERFAMILY SSF53223 18 197 4.8E-66 T 14-10-2018 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 PIRSF PIRSF000185 7 428 1.3E-176 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 Gene3D G3DSA:3.40.50.10860 47 182 3.1E-63 T 14-10-2018 C2I25_03950 3d8d7a55be670b7445597d9c677d0ada 428 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 114 127 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I25_03100 cf1ac28a3c494851afcb4d567af0a1f7 437 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 358 435 3.8E-14 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I25_03100 cf1ac28a3c494851afcb4d567af0a1f7 437 SUPERFAMILY SSF117143 94 397 2.75E-51 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like C2I25_03100 cf1ac28a3c494851afcb4d567af0a1f7 437 Pfam PF00460 Flagella basal body rod protein 5 35 3.8E-10 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I25_03100 cf1ac28a3c494851afcb4d567af0a1f7 437 Pfam PF07559 Flagellar basal body protein FlaE 186 312 1.2E-6 T 14-10-2018 IPR011491 Flagellar hook protein FlgE C2I25_03100 cf1ac28a3c494851afcb4d567af0a1f7 437 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 418 6.0E-69 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G C2I25_09855 e5f2df39f5f42610c99f239c46c7ebf8 229 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 28.157 T 14-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 C2I25_09855 e5f2df39f5f42610c99f239c46c7ebf8 229 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 9 223 1.1E-75 T 14-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 C2I25_09855 e5f2df39f5f42610c99f239c46c7ebf8 229 SUPERFAMILY SSF51395 6 223 9.16E-56 T 14-10-2018 C2I25_09855 e5f2df39f5f42610c99f239c46c7ebf8 229 Pfam PF01884 PcrB family 2 226 3.6E-87 T 14-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 C2I25_09855 e5f2df39f5f42610c99f239c46c7ebf8 229 Gene3D G3DSA:3.20.20.390 1 229 4.0E-98 T 14-10-2018 IPR038597 GGGP/HepGP synthase superfamily C2I25_05100 1145373c6383d73d00f5156d31fc6263 60 Pfam PF13121 Domain of unknown function (DUF3976) 17 56 3.9E-29 T 14-10-2018 IPR025008 Domain of unknown function DUF3976 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 Pfam PF00347 Ribosomal protein L6 91 165 2.2E-21 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 Pfam PF00347 Ribosomal protein L6 11 83 3.4E-23 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 SUPERFAMILY SSF56053 1 83 7.67E-27 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.4E-34 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.4E-34 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.4E-34 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 39.269 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 PIRSF PIRSF002162 1 178 5.8E-50 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 6.0E-77 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 Gene3D G3DSA:3.90.930.12 1 83 7.7E-32 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 Gene3D G3DSA:3.90.930.12 84 179 4.4E-41 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10895 3fb7e44f20606291de31e782260accc9 179 SUPERFAMILY SSF56053 84 177 2.65E-35 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 Pfam PF13354 Beta-lactamase enzyme family 79 284 4.1E-32 T 14-10-2018 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 Gene3D G3DSA:3.40.710.10 42 311 3.5E-82 T 14-10-2018 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 SUPERFAMILY SSF56601 57 308 1.35E-72 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 ProSitePatterns PS00146 Beta-lactamase class-A active site. 91 106 - T 14-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 PRINTS PR00118 Beta-lactamase class A signature 58 82 1.2E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 PRINTS PR00118 Beta-lactamase class A signature 191 216 1.2E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 PRINTS PR00118 Beta-lactamase class A signature 227 242 1.2E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 PRINTS PR00118 Beta-lactamase class A signature 89 106 1.2E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 PRINTS PR00118 Beta-lactamase class A signature 244 259 1.2E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 PRINTS PR00118 Beta-lactamase class A signature 129 154 1.2E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_27185 5846553e0f4aad18daa22fc848a9b0a7 312 PRINTS PR00118 Beta-lactamase class A signature 165 189 1.2E-68 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 SUPERFAMILY SSF53901 13 430 2.65E-78 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Gene3D G3DSA:3.30.70.3290 450 862 8.0E-141 T 14-10-2018 C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 SUPERFAMILY SSF51735 1037 1311 6.4E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Pfam PF07993 Male sterility protein 1039 1281 8.6E-47 T 14-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 267 383 2.7E-40 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 SUPERFAMILY SSF52151 530 818 1.07E-68 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 387 495 3.4E-18 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Gene3D G3DSA:3.40.47.10 12 436 1.3E-150 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 259 8.0E-66 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Gene3D G3DSA:3.40.50.720 1029 1407 7.6E-74 T 14-10-2018 C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 SUPERFAMILY SSF55048 660 719 2.75E-7 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Pfam PF00698 Acyl transferase domain 531 815 6.5E-49 T 14-10-2018 IPR014043 Acyl transferase C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 SMART SM00825 Beta-ketoacyl synthase 15 436 8.2E-165 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Pfam PF00550 Phosphopantetheine attachment site 915 975 1.8E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 SUPERFAMILY SSF47336 908 976 7.33E-13 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 172 188 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Gene3D G3DSA:3.40.366.10 529 831 8.0E-141 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Gene3D G3DSA:1.10.1200.10 905 983 4.2E-16 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 533 830 1.0E-90 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 ProSitePatterns PS00012 Phosphopantetheine attachment site. 937 952 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_02065 c0e14e2aa8f35f84755f505998c7ad50 1408 Gene3D G3DSA:3.30.70.250 661 721 8.0E-141 T 14-10-2018 C2I25_10905 0a8b9c4db87204f6ab3c67991aa791df 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 3.4E-25 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10905 0a8b9c4db87204f6ab3c67991aa791df 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 14-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10905 0a8b9c4db87204f6ab3c67991aa791df 61 SUPERFAMILY SSF57716 3 61 5.42E-22 T 14-10-2018 C2I25_10905 0a8b9c4db87204f6ab3c67991aa791df 61 Gene3D G3DSA:4.10.830.10 1 61 4.8E-31 T 14-10-2018 C2I25_10905 0a8b9c4db87204f6ab3c67991aa791df 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.091 T 14-10-2018 IPR023053 Ribosomal protein S14, type Z C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 164 175 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 207 234 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 358 371 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 281 296 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 302 319 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 69 87 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 264 279 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 130 142 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 33 49 2.8E-62 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 Gene3D G3DSA:3.20.20.10 15 230 2.7E-134 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 SUPERFAMILY SSF50621 243 381 1.12E-52 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 TIGRFAM TIGR00492 alr: alanine racemase 7 375 2.9E-122 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 SUPERFAMILY SSF51419 13 249 1.13E-66 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 Pfam PF01168 Alanine racemase, N-terminal domain 13 234 8.6E-68 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 SMART SM01005 248 376 1.1E-70 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 Hamap MF_01201 Alanine racemase. 6 376 34.626 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 Gene3D G3DSA:2.40.37.10 11 375 2.7E-134 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 Pfam PF00842 Alanine racemase, C-terminal domain 248 375 3.3E-47 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_01250 313766fc8aa383a8adbdd31f0398335f 391 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 PIRSF PIRSF036643 1 968 0.0 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 SUPERFAMILY SSF53706 255 788 3.66E-194 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Gene3D G3DSA:3.40.50.740 323 782 9.5E-164 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 SUPERFAMILY SSF54862 136 218 9.42E-17 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Pfam PF00384 Molybdopterin oxidoreductase 318 742 1.0E-86 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 262 315 1.6E-18 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 124 2.3E-10 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 SMART SM00926 261 315 3.3E-18 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 SMART SM00929 85 126 1.9E-12 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 SUPERFAMILY SSF50692 789 936 3.62E-35 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Gene3D G3DSA:3.40.228.10 396 595 9.5E-164 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Pfam PF12838 4Fe-4S dicluster domain 150 208 2.8E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Pfam PF01568 Molydopterin dinucleotide binding domain 824 931 8.1E-21 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Gene3D G3DSA:3.30.70.20 130 212 2.6E-20 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 77 4.9E-18 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Gene3D G3DSA:3.10.20.740 5 126 1.1E-30 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Gene3D G3DSA:2.20.25.90 261 316 4.6E-19 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 Gene3D G3DSA:2.40.40.20 816 942 4.3E-27 T 14-10-2018 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 SUPERFAMILY SSF54292 5 128 6.77E-32 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I25_21710 5ff56a6d8d8bb2726b03b49d29adcb20 979 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 266 934 1.4E-247 T 14-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 C2I25_14200 312d289306dcfc76384e1dfb8a99ff7c 143 SUPERFAMILY SSF82649 2 141 2.72E-52 T 14-10-2018 C2I25_14200 312d289306dcfc76384e1dfb8a99ff7c 143 Gene3D G3DSA:3.90.1010.10 2 143 5.7E-61 T 14-10-2018 C2I25_14200 312d289306dcfc76384e1dfb8a99ff7c 143 Pfam PF01592 NifU-like N terminal domain 10 127 2.5E-37 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 C2I25_14200 312d289306dcfc76384e1dfb8a99ff7c 143 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 139 1.6E-56 T 14-10-2018 C2I25_09875 d1963136ee00c06e71a50e4078701555 289 Gene3D G3DSA:3.40.190.290 82 282 2.6E-35 T 14-10-2018 C2I25_09875 d1963136ee00c06e71a50e4078701555 289 SUPERFAMILY SSF53850 85 282 2.95E-33 T 14-10-2018 C2I25_09875 d1963136ee00c06e71a50e4078701555 289 Gene3D G3DSA:1.10.10.10 1 81 9.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_09875 d1963136ee00c06e71a50e4078701555 289 Pfam PF03466 LysR substrate binding domain 86 282 3.6E-37 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_09875 d1963136ee00c06e71a50e4078701555 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.8E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_09875 d1963136ee00c06e71a50e4078701555 289 SUPERFAMILY SSF46785 1 110 6.54E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 SUPERFAMILY SSF53448 743 1016 6.1E-61 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 SUPERFAMILY SSF51445 108 410 4.77E-39 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 Gene3D G3DSA:3.20.20.370 466 686 2.7E-68 T 14-10-2018 C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 Gene3D G3DSA:3.20.20.80 131 405 8.9E-75 T 14-10-2018 C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 Pfam PF01522 Polysaccharide deacetylase 479 586 2.1E-29 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 Gene3D G3DSA:3.10.50.10 316 371 8.9E-75 T 14-10-2018 IPR029070 Chitinase insertion domain superfamily C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 Gene3D G3DSA:3.90.550.10 733 965 1.0E-52 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 SMART SM00636 108 400 8.3E-11 T 14-10-2018 IPR011583 Chitinase II GO:0008061 C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 SUPERFAMILY SSF88713 466 679 2.72E-56 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 Pfam PF00704 Glycosyl hydrolases family 18 113 399 3.3E-22 T 14-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 C2I25_22590 3c65b33b5f8261f62799be26bff58810 1115 Pfam PF13641 Glycosyltransferase like family 2 754 976 4.1E-36 T 14-10-2018 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 SUPERFAMILY SSF53067 253 501 4.56E-69 T 14-10-2018 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 250 4.1E-72 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 PIRSF PIRSF000538 4 506 2.9E-140 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 Gene3D G3DSA:3.30.420.40 252 512 7.0E-91 T 14-10-2018 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 6 510 2.1E-251 T 14-10-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 Gene3D G3DSA:3.30.420.40 2 251 3.4E-80 T 14-10-2018 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 SUPERFAMILY SSF53067 5 252 1.12E-69 T 14-10-2018 C2I25_22935 f8d761f8766eccf8734c62caf56b5c8e 513 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 454 7.4E-36 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 91 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 34 50 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 124 140 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 186 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 293 319 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 149 163 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 106 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 204 223 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 248 267 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 50 71 6.3E-49 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 PIRSF PIRSF019574 1 348 7.0E-108 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 Gene3D G3DSA:3.40.190.10 32 311 1.4E-111 T 14-10-2018 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 Gene3D G3DSA:3.40.190.10 134 341 1.4E-111 T 14-10-2018 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 SUPERFAMILY SSF53850 28 345 5.85E-90 T 14-10-2018 C2I25_04975 7e93cfa87858d423769fe79c68764eba 349 Pfam PF13416 Bacterial extracellular solute-binding protein 45 311 9.2E-43 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I25_10005 ef77517af6130e86bea8880717a2e465 240 SUPERFAMILY SSF53335 100 176 2.05E-14 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_10005 ef77517af6130e86bea8880717a2e465 240 Pfam PF08241 Methyltransferase domain 98 149 2.3E-13 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_10005 ef77517af6130e86bea8880717a2e465 240 Gene3D G3DSA:3.40.50.150 75 217 1.8E-15 T 14-10-2018 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 PIRSF PIRSF000513 4 268 4.1E-96 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 12 255 8.9E-95 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 260 33.235 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 SUPERFAMILY SSF53613 11 267 5.86E-61 T 14-10-2018 IPR029056 Ribokinase-like C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 Pfam PF02110 Hydroxyethylthiazole kinase family 12 253 1.2E-91 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 Gene3D G3DSA:3.40.1190.20 1 269 1.6E-99 T 14-10-2018 IPR029056 Ribokinase-like C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 2.8E-41 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 2.8E-41 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 2.8E-41 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 2.8E-41 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 2.8E-41 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09430 01bd27f480354fb8b65e74e15f8dc8a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 163 180 2.8E-41 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09175 063f8cb2517a716b8ee5fad80944c903 260 SUPERFAMILY SSF88713 45 255 8.9E-67 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_09175 063f8cb2517a716b8ee5fad80944c903 260 Gene3D G3DSA:3.20.20.370 20 260 1.9E-98 T 14-10-2018 C2I25_09175 063f8cb2517a716b8ee5fad80944c903 260 Pfam PF01522 Polysaccharide deacetylase 64 185 9.2E-35 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_09175 063f8cb2517a716b8ee5fad80944c903 260 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 32 254 1.2E-115 T 14-10-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA C2I25_03005 39780681e4eeb3c148962703465af5c7 436 SMART SM00962 241 434 7.7E-40 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_03005 39780681e4eeb3c148962703465af5c7 436 Gene3D G3DSA:3.40.50.300 237 422 1.7E-50 T 14-10-2018 C2I25_03005 39780681e4eeb3c148962703465af5c7 436 SUPERFAMILY SSF52540 239 426 1.96E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03005 39780681e4eeb3c148962703465af5c7 436 Pfam PF00448 SRP54-type protein, GTPase domain 243 433 7.4E-40 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_03005 39780681e4eeb3c148962703465af5c7 436 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 10 330 7.6E-52 T 14-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 C2I25_03005 39780681e4eeb3c148962703465af5c7 436 SMART SM00382 240 378 2.1E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_03005 39780681e4eeb3c148962703465af5c7 436 Gene3D G3DSA:1.20.120.1380 187 424 1.7E-50 T 14-10-2018 C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 SUPERFAMILY SSF52540 277 484 1.4E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 Gene3D G3DSA:3.40.50.300 1 216 4.5E-48 T 14-10-2018 C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 Gene3D G3DSA:3.40.50.300 254 511 5.7E-50 T 14-10-2018 C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 Pfam PF00005 ABC transporter 20 134 5.2E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 SMART SM00382 318 488 4.5E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 SMART SM00382 29 186 1.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 Pfam PF00005 ABC transporter 310 437 3.1E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 SUPERFAMILY SSF52540 3 214 4.63E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_26825 65cb4f061993090e2fd47cc6374fd00b 542 Pfam PF12848 ABC transporter 174 268 8.6E-10 T 14-10-2018 IPR032781 ABC-transporter extension domain C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 Pfam PF08239 Bacterial SH3 domain 48 94 8.0E-8 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 Pfam PF08239 Bacterial SH3 domain 188 237 1.1E-12 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 Pfam PF08239 Bacterial SH3 domain 114 163 1.5E-14 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 SUPERFAMILY SSF51261 242 382 1.1E-41 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 SMART SM00287 105 167 1.2E-11 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 SMART SM00287 38 99 0.045 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 SMART SM00287 179 241 6.1E-8 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 Pfam PF01551 Peptidase family M23 275 372 1.9E-29 T 14-10-2018 IPR016047 Peptidase M23 C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 Gene3D G3DSA:2.30.30.500 46 110 2.2E-15 T 14-10-2018 C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 Gene3D G3DSA:2.70.70.10 235 384 1.6E-37 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 Gene3D G3DSA:2.30.30.40 111 163 9.9E-16 T 14-10-2018 C2I25_07745 d14799f2ef4bbbce4def76b0834c0231 384 Gene3D G3DSA:2.30.30.40 178 234 5.1E-17 T 14-10-2018 C2I25_17960 913a3a66222b921a0141cea94d9abfd9 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.663 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17960 913a3a66222b921a0141cea94d9abfd9 49 SUPERFAMILY SSF57829 1 49 9.16E-18 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 C2I25_17960 913a3a66222b921a0141cea94d9abfd9 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17960 913a3a66222b921a0141cea94d9abfd9 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 2.3E-18 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17960 913a3a66222b921a0141cea94d9abfd9 49 Gene3D G3DSA:2.20.28.120 1 49 1.4E-22 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17960 913a3a66222b921a0141cea94d9abfd9 49 Pfam PF00471 Ribosomal protein L33 3 49 1.9E-20 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_02290 e67dd5999a897885893208c1c98159e9 608 Gene3D G3DSA:1.20.1740.10 21 465 1.9E-24 T 14-10-2018 C2I25_02290 e67dd5999a897885893208c1c98159e9 608 Pfam PF13520 Amino acid permease 29 444 5.1E-33 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_10660 a7c25becb7bb9a87511052b529048e2b 655 Gene3D G3DSA:2.120.10.30 168 310 4.1E-7 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I25_10660 a7c25becb7bb9a87511052b529048e2b 655 Pfam PF00326 Prolyl oligopeptidase family 447 644 8.3E-41 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 C2I25_10660 a7c25becb7bb9a87511052b529048e2b 655 Gene3D G3DSA:2.120.10.30 11 160 4.1E-17 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I25_10660 a7c25becb7bb9a87511052b529048e2b 655 SUPERFAMILY SSF82171 20 357 1.44E-32 T 14-10-2018 C2I25_10660 a7c25becb7bb9a87511052b529048e2b 655 Gene3D G3DSA:3.40.50.1820 339 645 1.0E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_10660 a7c25becb7bb9a87511052b529048e2b 655 SUPERFAMILY SSF53474 388 643 3.62E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_10660 a7c25becb7bb9a87511052b529048e2b 655 Pfam PF07676 WD40-like Beta Propeller Repeat 63 98 0.032 T 14-10-2018 IPR011659 WD40-like Beta Propeller C2I25_05515 d40d573ff4acdd9e277985715917b2fb 248 Pfam PF12227 Protein of unknown function (DUF3603) 35 248 4.2E-113 T 14-10-2018 IPR020909 UPF0736 C2I25_05515 d40d573ff4acdd9e277985715917b2fb 248 Hamap MF_01860 UPF0736 protein . 1 248 51.639 T 14-10-2018 IPR020909 UPF0736 C2I25_11135 102a1d61c6e09308f2075b549ebb19cc 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 5.7E-58 T 14-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 C2I25_11135 102a1d61c6e09308f2075b549ebb19cc 153 PIRSF PIRSF010607 1 153 1.1E-66 T 14-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 C2I25_11135 102a1d61c6e09308f2075b549ebb19cc 153 Gene3D G3DSA:1.10.10.1240 2 72 2.7E-35 T 14-10-2018 C2I25_11135 102a1d61c6e09308f2075b549ebb19cc 153 Gene3D G3DSA:1.10.1200.150 73 153 3.5E-31 T 14-10-2018 C2I25_01610 adaeb7776b1cb9283566a3711ce0cb2c 102 SUPERFAMILY SSF46785 2 93 7.17E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01610 adaeb7776b1cb9283566a3711ce0cb2c 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 6.9E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_01610 adaeb7776b1cb9283566a3711ce0cb2c 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 6.9E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_01610 adaeb7776b1cb9283566a3711ce0cb2c 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 6.9E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_01610 adaeb7776b1cb9283566a3711ce0cb2c 102 SMART SM00418 16 93 8.0E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_01610 adaeb7776b1cb9283566a3711ce0cb2c 102 Gene3D G3DSA:1.10.10.10 3 97 2.1E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01610 adaeb7776b1cb9283566a3711ce0cb2c 102 Pfam PF01022 Bacterial regulatory protein, arsR family 23 65 2.6E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_13315 5a76c8a6754147fcc54072d137c5bf66 297 Pfam PF02687 FtsX-like permease family 202 286 1.0E-5 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_13315 5a76c8a6754147fcc54072d137c5bf66 297 PIRSF PIRSF003097 1 297 1.6E-88 T 14-10-2018 IPR004513 Cell division protein FtsX GO:0016021 C2I25_13315 5a76c8a6754147fcc54072d137c5bf66 297 Gene3D G3DSA:3.30.70.3040 47 156 5.7E-6 T 14-10-2018 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 SMART SM00357 75 137 2.1E-12 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 SMART SM00357 139 206 0.0078 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 SUPERFAMILY SSF50249 130 229 3.94E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 Gene3D G3DSA:2.40.50.140 633 740 2.6E-25 T 14-10-2018 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 SUPERFAMILY SSF50249 630 710 2.33E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 Pfam PF00575 S1 RNA binding domain 629 711 1.1E-14 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 SUPERFAMILY SSF50249 212 629 4.11E-149 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 SMART SM00955 252 582 1.1E-179 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 Pfam PF08206 Ribonuclease B OB domain 151 205 2.0E-7 T 14-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 Pfam PF08206 Ribonuclease B OB domain 76 136 2.0E-21 T 14-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 Gene3D G3DSA:2.40.50.140 61 138 8.0E-18 T 14-10-2018 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 Gene3D G3DSA:2.40.50.140 139 207 5.8E-8 T 14-10-2018 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 ProSitePatterns PS01175 Ribonuclease II family signature. 549 573 - T 14-10-2018 IPR022966 Ribonuclease II/R, conserved site C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 SMART SM00316 630 712 3.6E-19 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 TIGRFAM TIGR02063 RNase_R: ribonuclease R 11 712 1.1E-285 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 Hamap MF_01895 Ribonuclease R [rnr]. 27 712 60.827 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 SUPERFAMILY SSF50249 57 139 3.94E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 Pfam PF00773 RNB domain 252 580 5.9E-113 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 C2I25_13580 d72f62cc3299a29c72faf8911d7f7ea4 812 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 63 712 8.8E-250 T 14-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 C2I25_07000 662dd4d984df07e01d14e17bb5f693c7 252 PIRSF PIRSF001332 5 250 2.2E-105 T 14-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 C2I25_07000 662dd4d984df07e01d14e17bb5f693c7 252 Gene3D G3DSA:3.30.1330.80 20 236 1.0E-87 T 14-10-2018 C2I25_07000 662dd4d984df07e01d14e17bb5f693c7 252 SUPERFAMILY SSF117856 18 249 1.73E-88 T 14-10-2018 C2I25_07000 662dd4d984df07e01d14e17bb5f693c7 252 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 18 249 3.4E-98 T 14-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 C2I25_07000 662dd4d984df07e01d14e17bb5f693c7 252 Pfam PF03306 Alpha-acetolactate decarboxylase 20 237 2.9E-89 T 14-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 C2I25_07000 662dd4d984df07e01d14e17bb5f693c7 252 Gene3D G3DSA:3.30.1330.80 95 217 1.0E-87 T 14-10-2018 C2I25_11370 81e573045aac7cf1746daa9af704f03e 97 SUPERFAMILY SSF160537 1 86 2.09E-33 T 14-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 C2I25_11370 81e573045aac7cf1746daa9af704f03e 97 Gene3D G3DSA:3.30.1120.40 1 97 1.9E-39 T 14-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 C2I25_11370 81e573045aac7cf1746daa9af704f03e 97 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 95 28.22 T 14-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 C2I25_11370 81e573045aac7cf1746daa9af704f03e 97 Pfam PF04026 SpoVG 1 81 9.0E-36 T 14-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 C2I25_00970 5b10b15640aa17cdafd57418fa00cf75 105 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 7 103 2.6E-25 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 C2I25_00970 5b10b15640aa17cdafd57418fa00cf75 105 Gene3D G3DSA:2.102.10.10 3 105 3.0E-28 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I25_00970 5b10b15640aa17cdafd57418fa00cf75 105 Pfam PF13806 Rieske-like [2Fe-2S] domain 9 103 2.0E-14 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 C2I25_00970 5b10b15640aa17cdafd57418fa00cf75 105 SUPERFAMILY SSF50022 7 105 5.5E-31 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I25_21045 4f06f13625ec0560710780b70939d438 527 ProSitePatterns PS00786 5'-nucleotidase signature 2. 91 102 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 Gene3D G3DSA:3.60.21.10 7 317 2.0E-90 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_21045 4f06f13625ec0560710780b70939d438 527 Pfam PF00149 Calcineurin-like phosphoesterase 9 243 6.6E-13 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_21045 4f06f13625ec0560710780b70939d438 527 SUPERFAMILY SSF55816 315 526 6.8E-51 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 PRINTS PR01607 Apyrase family signature 373 396 2.2E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 PRINTS PR01607 Apyrase family signature 226 249 2.2E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 PRINTS PR01607 Apyrase family signature 7 25 2.2E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 PRINTS PR01607 Apyrase family signature 463 482 2.2E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 PRINTS PR01607 Apyrase family signature 191 208 2.2E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 PRINTS PR01607 Apyrase family signature 253 273 2.2E-25 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 Gene3D G3DSA:3.90.780.10 319 527 8.2E-70 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 Pfam PF02872 5'-nucleotidase, C-terminal domain 320 489 1.1E-29 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_21045 4f06f13625ec0560710780b70939d438 527 SUPERFAMILY SSF56300 3 317 6.33E-84 T 14-10-2018 C2I25_23595 435862397ecc941dab8d1e24c1b154e2 331 Gene3D G3DSA:3.40.50.1100 16 324 1.2E-109 T 14-10-2018 C2I25_23595 435862397ecc941dab8d1e24c1b154e2 331 Gene3D G3DSA:3.40.50.1100 48 156 1.2E-109 T 14-10-2018 C2I25_23595 435862397ecc941dab8d1e24c1b154e2 331 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 14 326 2.4E-98 T 14-10-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 C2I25_23595 435862397ecc941dab8d1e24c1b154e2 331 PIRSF PIRSF006278 1 331 9.9E-93 T 14-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase C2I25_23595 435862397ecc941dab8d1e24c1b154e2 331 SUPERFAMILY SSF53686 4 325 5.21E-90 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_23595 435862397ecc941dab8d1e24c1b154e2 331 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 318 6.2E-57 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 SUPERFAMILY SSF52540 3 162 4.91E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 Pfam PF07670 Nucleoside recognition 508 631 9.6E-34 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 Pfam PF07670 Nucleoside recognition 347 440 1.4E-15 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 Pfam PF02421 Ferrous iron transport protein B 3 153 6.1E-59 T 14-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 Gene3D G3DSA:3.40.50.300 1 170 5.0E-41 T 14-10-2018 C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 Pfam PF07664 Ferrous iron transport protein B C terminus 451 503 1.8E-18 T 14-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 628 7.5E-195 T 14-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 50 65 5.5E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_15150 0f900142ba6f9fa6cc34f1cd25297848 662 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 5.5E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_24615 bc2fc430c2b659bdb7da862ebfc897ef 546 PIRSF PIRSF010386 1 545 2.3E-238 T 14-10-2018 IPR012166 Uncharacterised protein family RocB C2I25_24615 bc2fc430c2b659bdb7da862ebfc897ef 546 SUPERFAMILY SSF53187 6 530 3.02E-34 T 14-10-2018 C2I25_24615 bc2fc430c2b659bdb7da862ebfc897ef 546 Pfam PF01546 Peptidase family M20/M25/M40 109 438 1.8E-11 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_24615 bc2fc430c2b659bdb7da862ebfc897ef 546 Gene3D G3DSA:3.40.630.10 4 229 5.0E-40 T 14-10-2018 C2I25_09750 7ff14c0f10bfffba8f34e9037845c737 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 201 4.9E-27 T 14-10-2018 C2I25_09750 7ff14c0f10bfffba8f34e9037845c737 248 Gene3D G3DSA:3.40.50.1000 7 228 5.8E-29 T 14-10-2018 IPR023214 HAD superfamily C2I25_09750 7ff14c0f10bfffba8f34e9037845c737 248 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 201 2.6E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_09750 7ff14c0f10bfffba8f34e9037845c737 248 Gene3D G3DSA:1.10.150.240 19 106 5.8E-29 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_09750 7ff14c0f10bfffba8f34e9037845c737 248 SUPERFAMILY SSF56784 1 232 1.44E-41 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_14365 3b1c3ab38f885050379210cce86f4292 292 Pfam PF01909 Nucleotidyltransferase domain 52 107 5.8E-5 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 C2I25_14365 3b1c3ab38f885050379210cce86f4292 292 Gene3D G3DSA:3.30.460.10 30 137 1.8E-6 T 14-10-2018 C2I25_14365 3b1c3ab38f885050379210cce86f4292 292 SUPERFAMILY SSF81301 60 107 4.91E-7 T 14-10-2018 C2I25_14365 3b1c3ab38f885050379210cce86f4292 292 Pfam PF13427 Domain of unknown function (DUF4111) 181 270 1.7E-5 T 14-10-2018 IPR025184 Domain of unknown function DUF4111 C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 Gene3D G3DSA:2.30.30.40 83 142 2.0E-14 T 14-10-2018 C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 SUPERFAMILY SSF50685 248 299 1.5E-10 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 Pfam PF08239 Bacterial SH3 domain 32 81 5.2E-11 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 Pfam PF08239 Bacterial SH3 domain 91 138 7.5E-10 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 SMART SM00287 23 84 1.6E-9 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 SMART SM00287 85 144 3.6E-9 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 Pfam PF06725 3D domain 249 309 7.8E-20 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 Gene3D G3DSA:2.40.40.10 158 302 3.2E-8 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_20955 98fc4cf214233f20fd4aadc442025576 310 Gene3D G3DSA:2.30.30.40 19 82 1.9E-15 T 14-10-2018 C2I25_17225 3616b32e768a45ea35f7a45e48b7a9d2 779 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 29 562 1.8E-183 T 14-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 C2I25_17225 3616b32e768a45ea35f7a45e48b7a9d2 779 Gene3D G3DSA:3.90.1640.30 57 318 3.6E-95 T 14-10-2018 C2I25_17225 3616b32e768a45ea35f7a45e48b7a9d2 779 SUPERFAMILY SSF64182 57 452 2.35E-123 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily C2I25_17225 3616b32e768a45ea35f7a45e48b7a9d2 779 Pfam PF01368 DHH family 83 209 1.8E-9 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_17225 3616b32e768a45ea35f7a45e48b7a9d2 779 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 568 766 1.1E-65 T 14-10-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal C2I25_17225 3616b32e768a45ea35f7a45e48b7a9d2 779 Pfam PF02272 DHHA1 domain 315 439 1.1E-20 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I25_17225 3616b32e768a45ea35f7a45e48b7a9d2 779 Gene3D G3DSA:3.10.310.30 320 444 3.6E-35 T 14-10-2018 C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 10 138 1.6E-39 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 4.3E-27 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 4.3E-27 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 4.3E-27 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 4.3E-27 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 4.3E-27 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 SUPERFAMILY SSF50891 14 138 9.64E-47 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 Gene3D G3DSA:2.40.100.10 1 145 2.2E-58 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_19155 5b49f8b8315535586a4110c9d665302b 145 PIRSF PIRSF001467 6 145 1.7E-40 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 C2I25_14010 e8e54a5261023ca304ea8486c568d26c 252 Pfam PF11495 Archaeal transcriptional regulator TrmB 102 222 7.0E-6 T 14-10-2018 IPR021586 Transcription regulator TrmB, C-terminal C2I25_14010 e8e54a5261023ca304ea8486c568d26c 252 SUPERFAMILY SSF46785 1 70 3.83E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_14010 e8e54a5261023ca304ea8486c568d26c 252 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 70 8.1E-21 T 14-10-2018 IPR002831 Transcription regulator TrmB, N-terminal C2I25_14010 e8e54a5261023ca304ea8486c568d26c 252 Gene3D G3DSA:1.10.10.10 1 95 1.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22525 adbd3dc144ba6a2aaacdafb1587bdcf4 113 PIRSF PIRSF029876 3 111 7.7E-46 T 14-10-2018 IPR008316 Uncharacterised conserved protein UCP029876 C2I25_22525 adbd3dc144ba6a2aaacdafb1587bdcf4 113 Gene3D G3DSA:1.10.1900.10 1 109 1.5E-39 T 14-10-2018 C2I25_22525 adbd3dc144ba6a2aaacdafb1587bdcf4 113 SUPERFAMILY SSF158560 1 108 1.7E-35 T 14-10-2018 C2I25_22525 adbd3dc144ba6a2aaacdafb1587bdcf4 113 Pfam PF06304 Protein of unknown function (DUF1048) 7 106 2.5E-42 T 14-10-2018 IPR008316 Uncharacterised conserved protein UCP029876 C2I25_11800 2ef2d411ce7b8a0316fb8bcf0be14c7b 264 SUPERFAMILY SSF56281 3 251 1.27E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_11800 2ef2d411ce7b8a0316fb8bcf0be14c7b 264 Pfam PF00753 Metallo-beta-lactamase superfamily 12 218 6.1E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_11800 2ef2d411ce7b8a0316fb8bcf0be14c7b 264 SMART SM00849 13 193 5.4E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_11800 2ef2d411ce7b8a0316fb8bcf0be14c7b 264 Gene3D G3DSA:3.60.15.10 9 249 1.1E-41 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 SUPERFAMILY SSF48179 161 268 1.38E-38 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 5.8E-87 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 3.2E-40 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 Gene3D G3DSA:1.10.3730.10 164 271 2.2E-39 T 14-10-2018 C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 SUPERFAMILY SSF51735 3 160 2.51E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 Gene3D G3DSA:3.40.50.720 1 163 1.4E-52 T 14-10-2018 C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 27.24 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 PIRSF PIRSF000193 2 269 3.1E-86 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_24620 704596a836ae89a5c982808bb4f9981b 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 2.8E-17 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I25_15675 a0560875694b4d0757b0bc55ff43dbf2 164 Pfam PF02559 CarD-like/TRCF domain 7 115 6.6E-21 T 14-10-2018 IPR003711 CarD-like/TRCF domain C2I25_15675 a0560875694b4d0757b0bc55ff43dbf2 164 SUPERFAMILY SSF141259 7 70 3.01E-14 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily C2I25_15675 a0560875694b4d0757b0bc55ff43dbf2 164 SMART SM01058 6 116 3.7E-35 T 14-10-2018 IPR003711 CarD-like/TRCF domain C2I25_15675 a0560875694b4d0757b0bc55ff43dbf2 164 Gene3D G3DSA:2.30.30.840 2 67 8.2E-27 T 14-10-2018 C2I25_15675 a0560875694b4d0757b0bc55ff43dbf2 164 Gene3D G3DSA:1.20.58.1290 68 164 8.2E-29 T 14-10-2018 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 16 185 31.483 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 SUPERFAMILY SSF55200 97 186 2.35E-33 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 22 91 7.8E-34 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 Gene3D G3DSA:3.30.110.10 94 186 6.3E-38 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 22 184 1.5E-76 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 Gene3D G3DSA:3.10.20.80 16 93 1.4E-35 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 SUPERFAMILY SSF54364 20 93 2.35E-30 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 98 183 1.8E-38 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 C2I25_16435 db67300f0426f43b9f08eb4627bfe413 186 ProSitePatterns PS00938 Initiation factor 3 signature. 73 86 - T 14-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 C2I25_12585 dd08e9054e2210ee2fac8bcd2d69fd12 147 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 146 1.2E-59 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I25_12585 dd08e9054e2210ee2fac8bcd2d69fd12 147 SUPERFAMILY SSF89623 1 145 4.71E-57 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I25_12585 dd08e9054e2210ee2fac8bcd2d69fd12 147 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 1.8E-48 T 14-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 C2I25_12585 dd08e9054e2210ee2fac8bcd2d69fd12 147 Gene3D G3DSA:3.40.1400.10 1 147 8.0E-58 T 14-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I25_12585 dd08e9054e2210ee2fac8bcd2d69fd12 147 Pfam PF02502 Ribose/Galactose Isomerase 3 141 5.5E-54 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I25_12585 dd08e9054e2210ee2fac8bcd2d69fd12 147 PIRSF PIRSF005384 1 147 3.5E-57 T 14-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I25_03830 dc944d54789872f53e3b017c806471e3 320 Pfam PF00348 Polyprenyl synthetase 31 268 8.5E-64 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 C2I25_03830 dc944d54789872f53e3b017c806471e3 320 Gene3D G3DSA:1.10.600.10 7 320 4.3E-97 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I25_03830 dc944d54789872f53e3b017c806471e3 320 SUPERFAMILY SSF48576 7 319 3.2E-84 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I25_03830 dc944d54789872f53e3b017c806471e3 320 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 320 4.2E-172 T 14-10-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 C2I25_03830 dc944d54789872f53e3b017c806471e3 320 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site C2I25_03830 dc944d54789872f53e3b017c806471e3 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site C2I25_17950 bf2bd6d57ea51b3b4f442762f40fb9da 218 PIRSF PIRSF003107 1 218 1.9E-61 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 C2I25_17950 bf2bd6d57ea51b3b4f442762f40fb9da 218 Gene3D G3DSA:1.20.58.220 2 218 1.0E-70 T 14-10-2018 IPR038078 PhoU-like domain superfamily C2I25_17950 bf2bd6d57ea51b3b4f442762f40fb9da 218 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 213 1.7E-69 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 C2I25_17950 bf2bd6d57ea51b3b4f442762f40fb9da 218 SUPERFAMILY SSF109755 3 215 4.4E-63 T 14-10-2018 C2I25_17950 bf2bd6d57ea51b3b4f442762f40fb9da 218 Pfam PF01895 PhoU domain 18 104 1.9E-20 T 14-10-2018 IPR026022 PhoU domain C2I25_17950 bf2bd6d57ea51b3b4f442762f40fb9da 218 Pfam PF01895 PhoU domain 120 204 1.5E-19 T 14-10-2018 IPR026022 PhoU domain C2I25_05030 d5f2eb403853c81243eeafe78b9f4ba2 189 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 105 116 6.2E-7 T 14-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 C2I25_05030 d5f2eb403853c81243eeafe78b9f4ba2 189 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 47 62 6.2E-7 T 14-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 C2I25_05030 d5f2eb403853c81243eeafe78b9f4ba2 189 SUPERFAMILY SSF51306 41 118 9.42E-11 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I25_05030 d5f2eb403853c81243eeafe78b9f4ba2 189 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 167 3.7E-58 T 14-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 C2I25_05030 d5f2eb403853c81243eeafe78b9f4ba2 189 Pfam PF00717 Peptidase S24-like 47 104 3.1E-11 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I25_05030 d5f2eb403853c81243eeafe78b9f4ba2 189 Gene3D G3DSA:2.10.109.10 45 98 1.0E-5 T 14-10-2018 C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 Gene3D G3DSA:1.25.40.20 30 225 3.2E-55 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 Pfam PF12796 Ankyrin repeats (3 copies) 103 199 3.2E-12 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 Pfam PF12796 Ankyrin repeats (3 copies) 14 94 1.0E-12 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 SUPERFAMILY SSF48403 25 223 1.1E-51 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 PRINTS PR01415 Ankyrin repeat signature 130 145 3.8E-6 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 PRINTS PR01415 Ankyrin repeat signature 184 198 3.8E-6 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 SMART SM00248 63 92 5.0E-6 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 SMART SM00248 163 197 0.29 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 SMART SM00248 30 59 9.8 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 SMART SM00248 129 159 100.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_15925 6b3ea113e8ddce21cde24084ea4d5e3a 226 SMART SM00248 96 125 84.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_04690 5457be7c0d3c472dadb37591557995b5 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 3 57 3.2E-25 T 14-10-2018 IPR018690 Protein of unknown function DUF2187 C2I25_02595 7285956df5718dac83e895035d58559e 1064 Gene3D G3DSA:3.40.50.10810 583 817 3.0E-60 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily C2I25_02595 7285956df5718dac83e895035d58559e 1064 Gene3D G3DSA:3.40.50.300 821 1022 2.9E-85 T 14-10-2018 C2I25_02595 7285956df5718dac83e895035d58559e 1064 Pfam PF08455 Bacterial SNF2 helicase associated 235 606 3.4E-84 T 14-10-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial C2I25_02595 7285956df5718dac83e895035d58559e 1064 Pfam PF00271 Helicase conserved C-terminal domain 897 1008 3.5E-22 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_02595 7285956df5718dac83e895035d58559e 1064 Gene3D G3DSA:1.20.120.850 836 1058 2.9E-85 T 14-10-2018 C2I25_02595 7285956df5718dac83e895035d58559e 1064 Pfam PF00176 SNF2 family N-terminal domain 568 886 2.8E-49 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 C2I25_02595 7285956df5718dac83e895035d58559e 1064 SMART SM00490 926 1008 1.9E-24 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_02595 7285956df5718dac83e895035d58559e 1064 SMART SM00487 609 795 1.7E-29 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_02595 7285956df5718dac83e895035d58559e 1064 SUPERFAMILY SSF52540 592 814 2.92E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02595 7285956df5718dac83e895035d58559e 1064 SUPERFAMILY SSF52540 816 1063 3.33E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02595 7285956df5718dac83e895035d58559e 1064 Pfam PF04434 SWIM zinc finger 53 91 1.0E-4 T 14-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 C2I25_18855 59a7fca5114fe9391b5708ed4f7fc5e7 242 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 172 8.1E-51 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 C2I25_18855 59a7fca5114fe9391b5708ed4f7fc5e7 242 PIRSF PIRSF006755 1 230 2.8E-62 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 C2I25_18855 59a7fca5114fe9391b5708ed4f7fc5e7 242 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 219 29.458 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 C2I25_18855 59a7fca5114fe9391b5708ed4f7fc5e7 242 Gene3D G3DSA:3.40.50.300 2 219 1.6E-60 T 14-10-2018 C2I25_18855 59a7fca5114fe9391b5708ed4f7fc5e7 242 SUPERFAMILY SSF52540 1 206 7.19E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18855 59a7fca5114fe9391b5708ed4f7fc5e7 242 Pfam PF13500 AAA domain 4 203 4.5E-45 T 14-10-2018 C2I25_26875 881c8e779331ee0ec2dfbe3b4fa8d883 165 Gene3D G3DSA:3.30.240.20 75 148 1.2E-17 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_26875 881c8e779331ee0ec2dfbe3b4fa8d883 165 Pfam PF04239 Protein of unknown function (DUF421) 82 154 2.6E-17 T 14-10-2018 IPR007353 Protein of unknown function DUF421 C2I25_24380 9920ad8a3c809df556a04ab0e98deb8c 313 Gene3D G3DSA:3.40.710.10 2 303 2.5E-73 T 14-10-2018 C2I25_24380 9920ad8a3c809df556a04ab0e98deb8c 313 Pfam PF00144 Beta-lactamase 21 290 8.3E-32 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_24380 9920ad8a3c809df556a04ab0e98deb8c 313 SUPERFAMILY SSF56601 14 309 7.84E-75 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_16490 93e5d6f3707785c77401368e904b4cab 185 Gene3D G3DSA:1.10.3210.10 4 181 5.9E-14 T 14-10-2018 C2I25_16490 93e5d6f3707785c77401368e904b4cab 185 SUPERFAMILY SSF109604 19 137 5.76E-17 T 14-10-2018 C2I25_16490 93e5d6f3707785c77401368e904b4cab 185 Pfam PF01966 HD domain 26 135 6.2E-11 T 14-10-2018 IPR006674 HD domain C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 SUPERFAMILY SSF51230 1 84 1.83E-21 T 14-10-2018 IPR011053 Single hybrid motif C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 SUPERFAMILY SSF52777 172 399 3.11E-79 T 14-10-2018 C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 Pfam PF02817 e3 binding domain 119 154 1.1E-14 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 SUPERFAMILY SSF47005 116 157 4.05E-10 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 Gene3D G3DSA:2.40.50.100 2 100 1.2E-22 T 14-10-2018 C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 Gene3D G3DSA:3.30.559.10 161 397 2.8E-84 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 171 398 3.9E-82 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 Gene3D G3DSA:4.10.320.10 112 160 3.1E-16 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I25_25710 c4d41fab20359848450e7f893c04c24d 399 Pfam PF00364 Biotin-requiring enzyme 4 76 2.7E-16 T 14-10-2018 IPR000089 Biotin/lipoyl attachment C2I25_04290 bde488a70254e00c8d396f6fb745f961 203 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 7 191 1.0E-87 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I25_04290 bde488a70254e00c8d396f6fb745f961 203 Gene3D G3DSA:3.40.50.300 1 199 3.6E-85 T 14-10-2018 C2I25_04290 bde488a70254e00c8d396f6fb745f961 203 Pfam PF01583 Adenylylsulphate kinase 25 177 6.8E-74 T 14-10-2018 C2I25_04290 bde488a70254e00c8d396f6fb745f961 203 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 23 195 39.09 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I25_04290 bde488a70254e00c8d396f6fb745f961 203 SUPERFAMILY SSF52540 23 194 1.12E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09420 5331328b086c800847ce724fc642b0eb 437 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 369 2.5E-158 T 14-10-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 C2I25_09420 5331328b086c800847ce724fc642b0eb 437 PIRSF PIRSF004539 1 437 1.5E-192 T 14-10-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 C2I25_09420 5331328b086c800847ce724fc642b0eb 437 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 436 3.7E-173 T 14-10-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 SUPERFAMILY SSF101967 534 646 1.07E-7 T 14-10-2018 C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 SUPERFAMILY SSF58104 376 588 3.92E-7 T 14-10-2018 C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 1.0E-61 T 14-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 520 541 1.8E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 203 230 1.3E-6 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 563 586 4.2E-5 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 584 611 5.0E-7 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 282 305 2.5E-5 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 303 330 2.3E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 231 258 1.7E-6 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 612 639 3.5E-8 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 542 565 2.6E-6 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 Pfam PF12698 ABC-2 family transporter protein 686 872 2.2E-16 T 14-10-2018 C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 Pfam PF12698 ABC-2 family transporter protein 24 169 3.1E-15 T 14-10-2018 C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 SUPERFAMILY SSF58104 169 381 2.54E-5 T 14-10-2018 C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 Gene3D G3DSA:1.10.287.950 275 431 1.3E-5 T 14-10-2018 C2I25_06000 dd60aa88cdd070d87427b6a9dd324ed2 897 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 679 881 3.1E-66 T 14-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal C2I25_20520 e2d87095570d152a954094cade22ba4a 292 PIRSF PIRSF001365 1 292 5.5E-98 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 SUPERFAMILY SSF51569 2 289 9.11E-103 T 14-10-2018 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 Gene3D G3DSA:3.20.20.70 1 292 6.3E-125 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 2.3E-107 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 SMART SM01130 3 291 3.1E-138 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 63.496 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 289 1.9E-109 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 1.7E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 1.7E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 1.7E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_20520 e2d87095570d152a954094cade22ba4a 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 1.7E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_06375 9fea3a2e6c0fba40fd8e858c2aca9a63 338 SUPERFAMILY SSF51735 124 299 1.92E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_06375 9fea3a2e6c0fba40fd8e858c2aca9a63 338 Gene3D G3DSA:3.90.180.10 19 323 3.2E-111 T 14-10-2018 C2I25_06375 9fea3a2e6c0fba40fd8e858c2aca9a63 338 SMART SM00829 21 335 1.4E-8 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_06375 9fea3a2e6c0fba40fd8e858c2aca9a63 338 SUPERFAMILY SSF50129 14 155 2.28E-32 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_06375 9fea3a2e6c0fba40fd8e858c2aca9a63 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 39 97 2.3E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_06375 9fea3a2e6c0fba40fd8e858c2aca9a63 338 Pfam PF00107 Zinc-binding dehydrogenase 162 273 2.9E-15 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_06375 9fea3a2e6c0fba40fd8e858c2aca9a63 338 Gene3D G3DSA:3.40.50.720 146 271 3.2E-111 T 14-10-2018 C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 2.1E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 Gene3D G3DSA:3.10.20.580 449 555 4.3E-40 T 14-10-2018 C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 SMART SM00849 21 215 4.9E-26 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 SUPERFAMILY SSF56281 11 423 1.9E-96 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 48.256 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 397 1.0E-8 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 Gene3D G3DSA:3.60.15.10 12 442 5.2E-194 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 1.2E-232 T 14-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 PIRSF PIRSF004803 1 555 3.9E-249 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 14-10-2018 IPR001587 Ribonuclease J, conserved site C2I25_19600 2951399b93b721c4c8cd41e324e694f8 555 Gene3D G3DSA:3.40.50.10710 207 357 5.2E-194 T 14-10-2018 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 Gene3D G3DSA:1.50.10.10 70 426 8.7E-151 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 244 261 8.6E-31 T 14-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 412 426 8.6E-31 T 14-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 287 298 8.6E-31 T 14-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 316 325 8.6E-31 T 14-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 181 199 8.6E-31 T 14-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 119 132 8.6E-31 T 14-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 Pfam PF01270 Glycosyl hydrolases family 8 82 424 2.8E-28 T 14-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 SUPERFAMILY SSF48208 51 433 8.93E-106 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 C2I25_26200 94439eff56775d8d342fe1de3c5b8d52 453 ProSitePatterns PS00812 Glycosyl hydrolases family 8 signature. 181 199 - T 14-10-2018 IPR019834 Glycoside hydrolase, family 8, conserved site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 C2I25_27690 5c9addf5a8bba9f068a8dc7e77bca32b 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I25_27690 5c9addf5a8bba9f068a8dc7e77bca32b 156 Pfam PF01047 MarR family 36 91 9.7E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_27690 5c9addf5a8bba9f068a8dc7e77bca32b 156 Gene3D G3DSA:1.10.10.10 1 145 9.2E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_27690 5c9addf5a8bba9f068a8dc7e77bca32b 156 SMART SM00347 26 129 1.6E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_27690 5c9addf5a8bba9f068a8dc7e77bca32b 156 SUPERFAMILY SSF46785 6 147 1.75E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_06210 a2a3caab112bce6cd502c05dfc6d1b1c 289 Hamap MF_01145 Foldase protein PrsA [prsA]. 1 280 22.867 T 14-10-2018 IPR023059 Foldase protein PrsA GO:0003755 C2I25_06210 a2a3caab112bce6cd502c05dfc6d1b1c 289 Gene3D G3DSA:3.10.50.40 129 223 2.0E-39 T 14-10-2018 C2I25_06210 a2a3caab112bce6cd502c05dfc6d1b1c 289 SUPERFAMILY SSF54534 122 223 7.85E-35 T 14-10-2018 C2I25_06210 a2a3caab112bce6cd502c05dfc6d1b1c 289 SUPERFAMILY SSF109998 34 163 1.96E-19 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I25_06210 a2a3caab112bce6cd502c05dfc6d1b1c 289 Pfam PF13616 PPIC-type PPIASE domain 132 224 4.8E-29 T 14-10-2018 C2I25_06210 a2a3caab112bce6cd502c05dfc6d1b1c 289 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 162 183 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 C2I25_06210 a2a3caab112bce6cd502c05dfc6d1b1c 289 Gene3D G3DSA:1.10.3120.10 20 128 4.4E-7 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 C2I25_10500 36d1b506499e271395a171993eacce4e 315 Pfam PF12728 Helix-turn-helix domain 15 62 8.3E-16 T 14-10-2018 C2I25_10500 36d1b506499e271395a171993eacce4e 315 SUPERFAMILY SSF46955 15 62 5.31E-6 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_10500 36d1b506499e271395a171993eacce4e 315 Gene3D G3DSA:1.10.1660.10 12 64 5.4E-11 T 14-10-2018 C2I25_10500 36d1b506499e271395a171993eacce4e 315 SUPERFAMILY SSF53850 158 302 2.17E-18 T 14-10-2018 C2I25_10500 36d1b506499e271395a171993eacce4e 315 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 15 62 5.0E-20 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 C2I25_10500 36d1b506499e271395a171993eacce4e 315 Gene3D G3DSA:3.40.190.10 168 267 1.9E-6 T 14-10-2018 C2I25_10500 36d1b506499e271395a171993eacce4e 315 Pfam PF12727 PBP superfamily domain 98 282 6.0E-53 T 14-10-2018 IPR024370 PBP domain C2I25_16405 acff3b8507ee703139e8946486aac255 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 86.645 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 C2I25_16405 acff3b8507ee703139e8946486aac255 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 1.0E-67 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 C2I25_16405 acff3b8507ee703139e8946486aac255 153 Pfam PF03477 ATP cone domain 50 136 1.8E-20 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 C2I25_17610 18c0d306628ac3a0c17e89ce8603c9ed 97 SUPERFAMILY SSF75471 1 95 1.2E-31 T 14-10-2018 IPR035920 YhbY-like superfamily C2I25_17610 18c0d306628ac3a0c17e89ce8603c9ed 97 Gene3D G3DSA:3.30.110.60 1 97 1.8E-36 T 14-10-2018 IPR035920 YhbY-like superfamily C2I25_17610 18c0d306628ac3a0c17e89ce8603c9ed 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 97 2.0E-44 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 C2I25_17610 18c0d306628ac3a0c17e89ce8603c9ed 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 97 3.7E-41 T 14-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 C2I25_17610 18c0d306628ac3a0c17e89ce8603c9ed 97 SMART SM01103 2 85 1.5E-41 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 C2I25_17610 18c0d306628ac3a0c17e89ce8603c9ed 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 2.3E-22 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 PIRSF PIRSF006485 2 436 3.5E-172 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.883 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 SUPERFAMILY SSF52540 138 434 1.93E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 9.6E-34 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 6.2E-26 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 1.1E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 Gene3D G3DSA:3.40.50.300 170 352 9.7E-56 T 14-10-2018 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 4.6E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 4.6E-6 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 4.4E-179 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 339 2.3E-23 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 144 2.1E-23 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 Gene3D G3DSA:3.30.300.20 353 436 3.4E-35 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 Gene3D G3DSA:3.40.50.300 1 162 2.0E-46 T 14-10-2018 C2I25_03880 463d6d3a45a2b32202a1441d88569951 436 SUPERFAMILY SSF52540 5 167 6.97E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 SUPERFAMILY SSF53649 39 452 1.02E-130 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 Gene3D G3DSA:3.40.720.10 48 444 2.0E-148 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 Pfam PF00245 Alkaline phosphatase 44 450 1.0E-133 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 ProSitePatterns PS00123 Alkaline phosphatase active site. 99 107 - T 14-10-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 SMART SM00098 45 454 1.6E-198 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 252 281 1.2E-45 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 99 114 1.2E-45 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 44 64 1.2E-45 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 136 156 1.2E-45 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 186 196 1.2E-45 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_17545 2c84e4d7102bb11b282b785c14521a61 461 Gene3D G3DSA:1.10.60.40 328 413 2.0E-148 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Gene3D G3DSA:3.10.20.740 5 127 8.7E-28 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 SMART SM00926 261 315 6.8E-17 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 SMART SM00929 85 126 4.4E-13 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 78 2.4E-12 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 266 283 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 263 315 2.0E-17 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 266 934 7.1E-251 T 14-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Gene3D G3DSA:2.20.25.90 261 316 1.8E-18 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 SUPERFAMILY SSF50692 797 935 9.27E-34 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 SUPERFAMILY SSF53706 255 775 1.96E-193 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 SUPERFAMILY SSF54292 6 128 3.73E-29 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Pfam PF01568 Molydopterin dinucleotide binding domain 824 931 2.4E-20 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Gene3D G3DSA:3.40.50.740 323 782 5.0E-162 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Pfam PF00037 4Fe-4S binding domain 188 209 9.7E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Pfam PF00037 4Fe-4S binding domain 145 162 4.8E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 PIRSF PIRSF036643 1 968 0.0 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Gene3D G3DSA:2.40.40.20 817 943 9.3E-28 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 SUPERFAMILY SSF54862 136 218 1.15E-16 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 124 1.4E-10 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Gene3D G3DSA:3.40.228.10 396 595 5.0E-162 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Gene3D G3DSA:3.30.70.20 130 212 1.5E-19 T 14-10-2018 C2I25_08540 acf09b08998e7824f19513dfa87f2dd0 978 Pfam PF00384 Molybdopterin oxidoreductase 318 741 4.8E-81 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_04500 a55bb6b72e806260e25b05fb3791c250 452 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 1.5E-107 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_04500 a55bb6b72e806260e25b05fb3791c250 452 Pfam PF01554 MatE 20 180 4.0E-34 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_04500 a55bb6b72e806260e25b05fb3791c250 452 Pfam PF01554 MatE 247 408 1.3E-37 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_04500 a55bb6b72e806260e25b05fb3791c250 452 PIRSF PIRSF006603 1 452 3.4E-74 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_05080 9c76cb5d1114854ebd7d0a38e13d3d24 200 Pfam PF12870 Domain of unknown function (DUF4878) 28 109 2.9E-5 T 14-10-2018 IPR024267 Domain of unknown function (DUF4878) C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 Pfam PF00694 Aconitase C-terminal domain 701 828 2.1E-46 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 SUPERFAMILY SSF52016 640 898 1.37E-87 T 14-10-2018 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 219 234 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 440 451 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 147 160 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 502 515 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 281 294 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 171 179 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 375 389 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 295 308 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 PRINTS PR00415 Aconitase family signature 205 218 4.2E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 899 0.0 T 14-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 Gene3D G3DSA:1.10.1440.20 600 660 1.9E-23 T 14-10-2018 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 Pfam PF00330 Aconitase family (aconitate hydratase) 77 571 7.1E-176 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 Gene3D G3DSA:3.20.19.10 664 901 2.4E-103 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 SUPERFAMILY SSF53732 4 636 9.68E-227 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 Gene3D G3DSA:3.30.499.20 4 375 2.4E-158 T 14-10-2018 C2I25_21485 11c41360e159025fbc1a5daa6641e3a2 907 Gene3D G3DSA:3.30.499.10 376 599 1.3E-100 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 C2I25_17690 1753d2010443336b150588245bed4572 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 365 1.4E-128 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 C2I25_17690 1753d2010443336b150588245bed4572 379 Pfam PF04055 Radical SAM superfamily 7 177 1.4E-26 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_17690 1753d2010443336b150588245bed4572 379 Pfam PF06969 HemN C-terminal domain 303 365 9.4E-18 T 14-10-2018 IPR010723 HemN, C-terminal C2I25_17690 1753d2010443336b150588245bed4572 379 SMART SM00729 2 223 7.4E-65 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_17690 1753d2010443336b150588245bed4572 379 Gene3D G3DSA:3.80.30.20 3 301 1.2E-104 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I25_17690 1753d2010443336b150588245bed4572 379 SUPERFAMILY SSF102114 5 377 2.49E-121 T 14-10-2018 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 SMART SM00363 16 75 8.0E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 Pfam PF00849 RNA pseudouridylate synthase 89 242 2.5E-36 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 SUPERFAMILY SSF55174 16 102 6.73E-15 T 14-10-2018 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 SUPERFAMILY SSF55120 74 301 1.67E-80 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 Gene3D G3DSA:3.30.2350.10 81 302 8.7E-77 T 14-10-2018 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 Gene3D G3DSA:3.10.290.10 4 71 3.5E-20 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 Pfam PF01479 S4 domain 16 62 8.4E-11 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_20035 da433cfcbdb4442a6073e9b653cfa07b 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 301 6.7E-107 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_02840 9cce1a8c677125347f6091050af62ce5 368 Gene3D G3DSA:2.60.40.1640 222 368 5.2E-53 T 14-10-2018 C2I25_02840 9cce1a8c677125347f6091050af62ce5 368 Pfam PF13786 Domain of unknown function (DUF4179) 44 136 2.1E-18 T 14-10-2018 IPR025436 Domain of unknown function DUF4179 C2I25_02840 9cce1a8c677125347f6091050af62ce5 368 Gene3D G3DSA:2.60.40.1630 75 221 1.2E-51 T 14-10-2018 C2I25_14420 f0ce36312e7b7fc99c39690eb25eb988 265 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 9 257 5.3E-56 T 14-10-2018 IPR005226 UPF0014 family C2I25_14420 f0ce36312e7b7fc99c39690eb25eb988 265 Pfam PF03649 Uncharacterised protein family (UPF0014) 10 251 4.5E-84 T 14-10-2018 IPR005226 UPF0014 family C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 SUPERFAMILY SSF55874 258 407 1.83E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 Gene3D G3DSA:1.10.287.130 183 258 2.6E-11 T 14-10-2018 C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 SUPERFAMILY SSF47384 191 257 4.71E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 Gene3D G3DSA:3.30.565.10 261 408 1.5E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 SMART SM00388 197 260 3.1E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 354 5.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 5.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 368 5.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 406 5.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 302 406 4.6E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 SMART SM00387 302 408 6.8E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_09555 a31f0a6b291a5a6962f0cce23307282c 408 Pfam PF00512 His Kinase A (phospho-acceptor) domain 200 256 3.7E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_21505 26d28221797754ba4ce7ff33f77a81d8 315 SUPERFAMILY SSF53098 7 184 2.63E-55 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_21505 26d28221797754ba4ce7ff33f77a81d8 315 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 10 178 5.7E-30 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_21505 26d28221797754ba4ce7ff33f77a81d8 315 Pfam PF00929 Exonuclease 11 165 2.4E-35 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_21505 26d28221797754ba4ce7ff33f77a81d8 315 SMART SM00479 9 174 4.5E-49 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_21505 26d28221797754ba4ce7ff33f77a81d8 315 Gene3D G3DSA:3.30.420.10 8 175 1.5E-52 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_15530 8f790ef01ee7b2ff85037f8e4c4f7a89 619 PIRSF PIRSF018968 1 617 9.6E-59 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_15530 8f790ef01ee7b2ff85037f8e4c4f7a89 619 Pfam PF02687 FtsX-like permease family 84 179 6.0E-10 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_04730 fc9303bf17b65bafb7c9bc13404dd4ae 564 Gene3D G3DSA:1.10.1370.30 1 564 6.2E-236 T 14-10-2018 C2I25_04730 fc9303bf17b65bafb7c9bc13404dd4ae 564 SUPERFAMILY SSF55486 33 558 1.95E-124 T 14-10-2018 C2I25_04730 fc9303bf17b65bafb7c9bc13404dd4ae 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 13 560 4.0E-253 T 14-10-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related C2I25_17160 d489f881ca1e8aa32ff911345ae25680 314 Gene3D G3DSA:3.40.50.1980 160 314 1.7E-33 T 14-10-2018 C2I25_17160 d489f881ca1e8aa32ff911345ae25680 314 Pfam PF01497 Periplasmic binding protein 61 284 3.2E-31 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_17160 d489f881ca1e8aa32ff911345ae25680 314 SUPERFAMILY SSF53807 38 307 1.06E-59 T 14-10-2018 C2I25_17160 d489f881ca1e8aa32ff911345ae25680 314 Gene3D G3DSA:3.40.50.1980 35 158 2.2E-30 T 14-10-2018 C2I25_05485 d3d2bfc0912599badb6314bd699a9e76 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 154 338 2.5E-32 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_05485 d3d2bfc0912599badb6314bd699a9e76 338 SUPERFAMILY SSF161098 129 318 2.22E-31 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05485 d3d2bfc0912599badb6314bd699a9e76 338 Gene3D G3DSA:1.10.3720.10 125 337 2.6E-26 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05485 d3d2bfc0912599badb6314bd699a9e76 338 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 83 2.6E-14 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I25_06985 561a8240b9473c9daf2ae50a7ff85a2d 290 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 268 5.0E-48 T 14-10-2018 C2I25_06985 561a8240b9473c9daf2ae50a7ff85a2d 290 Gene3D G3DSA:3.30.1240.10 83 196 8.0E-70 T 14-10-2018 C2I25_06985 561a8240b9473c9daf2ae50a7ff85a2d 290 Gene3D G3DSA:3.40.50.1000 5 264 8.0E-70 T 14-10-2018 IPR023214 HAD superfamily C2I25_06985 561a8240b9473c9daf2ae50a7ff85a2d 290 SUPERFAMILY SSF56784 2 273 1.54E-52 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_26150 dcae9e5162f71edf723d42ab68e95c79 138 Pfam PF00583 Acetyltransferase (GNAT) family 20 116 3.4E-15 T 14-10-2018 IPR000182 GNAT domain C2I25_26150 dcae9e5162f71edf723d42ab68e95c79 138 SUPERFAMILY SSF55729 4 138 7.25E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26150 dcae9e5162f71edf723d42ab68e95c79 138 Gene3D G3DSA:3.40.630.30 35 138 3.6E-29 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01955 Frankia sp. LanC-like protein signature 355 375 2.4E-38 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01955 Frankia sp. LanC-like protein signature 110 126 2.4E-38 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01955 Frankia sp. LanC-like protein signature 306 329 2.4E-38 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01955 Frankia sp. LanC-like protein signature 62 77 2.4E-38 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01955 Frankia sp. LanC-like protein signature 165 181 2.4E-38 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01955 Frankia sp. LanC-like protein signature 259 279 2.4E-38 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01955 Frankia sp. LanC-like protein signature 235 259 2.4E-38 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 SMART SM01260 58 449 6.0E-56 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 Gene3D G3DSA:1.50.10.20 35 451 9.3E-115 T 14-10-2018 C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 Pfam PF05147 Lanthionine synthetase C-like protein 58 449 2.2E-75 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01950 LanC-like protein superfamily signature 61 79 4.5E-22 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01950 LanC-like protein superfamily signature 166 181 4.5E-22 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01950 LanC-like protein superfamily signature 306 326 4.5E-22 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01950 LanC-like protein superfamily signature 356 369 4.5E-22 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01950 LanC-like protein superfamily signature 238 254 4.5E-22 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 PRINTS PR01950 LanC-like protein superfamily signature 419 436 4.5E-22 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_21365 1d01b44f7b84414d79e0dd0160f29ce7 451 SUPERFAMILY SSF158745 55 451 1.18E-84 T 14-10-2018 C2I25_08925 730800585cd9d93f76bbe0796ec02a04 134 Gene3D G3DSA:1.10.287.70 21 132 2.6E-12 T 14-10-2018 C2I25_08925 730800585cd9d93f76bbe0796ec02a04 134 SUPERFAMILY SSF81324 25 123 7.2E-12 T 14-10-2018 C2I25_08925 730800585cd9d93f76bbe0796ec02a04 134 Pfam PF07885 Ion channel 44 126 3.8E-11 T 14-10-2018 IPR013099 Potassium channel domain C2I25_26260 79147b2e6d67e8e8c1900589bee8dcd0 419 Gene3D G3DSA:1.20.1250.20 11 404 8.7E-31 T 14-10-2018 C2I25_26260 79147b2e6d67e8e8c1900589bee8dcd0 419 Pfam PF05977 Transmembrane secretion effector 26 416 8.4E-22 T 14-10-2018 IPR010290 Transmembrane secretion effector C2I25_26260 79147b2e6d67e8e8c1900589bee8dcd0 419 SUPERFAMILY SSF103473 11 401 1.83E-34 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_26260 79147b2e6d67e8e8c1900589bee8dcd0 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 86 104 4.8E-7 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_26260 79147b2e6d67e8e8c1900589bee8dcd0 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 152 173 4.8E-7 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_26260 79147b2e6d67e8e8c1900589bee8dcd0 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 179 196 4.8E-7 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_26260 79147b2e6d67e8e8c1900589bee8dcd0 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 374 397 4.8E-7 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_26260 79147b2e6d67e8e8c1900589bee8dcd0 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 60 78 4.8E-7 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_16925 d32c963d11a955595df598db12f576c6 557 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 443 451 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 C2I25_16925 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 353 369 3.0E-32 T 14-10-2018 C2I25_16925 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 493 511 3.0E-32 T 14-10-2018 C2I25_16925 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 98 117 3.0E-32 T 14-10-2018 C2I25_16925 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 470 489 3.0E-32 T 14-10-2018 C2I25_16925 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 440 459 3.0E-32 T 14-10-2018 C2I25_16925 d32c963d11a955595df598db12f576c6 557 Gene3D G3DSA:3.40.50.300 53 264 4.6E-31 T 14-10-2018 C2I25_16925 d32c963d11a955595df598db12f576c6 557 SMART SM00382 90 268 1.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_16925 d32c963d11a955595df598db12f576c6 557 SUPERFAMILY SSF52540 56 329 1.17E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16925 d32c963d11a955595df598db12f576c6 557 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 94 267 3.9E-19 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_16925 d32c963d11a955595df598db12f576c6 557 SUPERFAMILY SSF54211 352 533 1.1E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_16925 d32c963d11a955595df598db12f576c6 557 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 351 534 1.9E-32 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 C2I25_16925 d32c963d11a955595df598db12f576c6 557 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 6 533 2.1E-279 T 14-10-2018 IPR014251 Sporulation protease LonB C2I25_16925 d32c963d11a955595df598db12f576c6 557 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 174 189 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I25_16925 d32c963d11a955595df598db12f576c6 557 Gene3D G3DSA:3.30.230.10 348 552 1.8E-49 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_04245 db25078c11965febab4e96c2e2a54401 424 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 5.0E-36 T 14-10-2018 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 5.0E-36 T 14-10-2018 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 5.0E-36 T 14-10-2018 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 5.0E-36 T 14-10-2018 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 5.0E-36 T 14-10-2018 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 5.0E-36 T 14-10-2018 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 5.0E-36 T 14-10-2018 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I25_04245 db25078c11965febab4e96c2e2a54401 424 Gene3D G3DSA:1.10.3860.10 1 418 1.2E-139 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 SUPERFAMILY SSF118215 6 402 4.84E-129 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 2.9E-126 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I25_04245 db25078c11965febab4e96c2e2a54401 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I25_11405 cf13ea748add0df282064a99d3e20b9d 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 78 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 C2I25_11405 cf13ea748add0df282064a99d3e20b9d 292 SMART SM00650 35 211 1.1E-85 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 C2I25_11405 cf13ea748add0df282064a99d3e20b9d 292 SUPERFAMILY SSF53335 16 286 5.23E-77 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_11405 cf13ea748add0df282064a99d3e20b9d 292 Gene3D G3DSA:1.10.8.100 219 288 1.7E-23 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 C2I25_11405 cf13ea748add0df282064a99d3e20b9d 292 Gene3D G3DSA:3.40.50.150 1 215 1.0E-74 T 14-10-2018 C2I25_11405 cf13ea748add0df282064a99d3e20b9d 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 19 280 2.5E-76 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm C2I25_11405 cf13ea748add0df282064a99d3e20b9d 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 19 287 56.956 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 C2I25_11405 cf13ea748add0df282064a99d3e20b9d 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 19 286 1.3E-88 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 SUPERFAMILY SSF48179 205 324 1.02E-20 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 204 1.3E-42 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 SUPERFAMILY SSF51735 1 205 3.15E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_14045 315cb6a1355e170360eacd931e230f75 793 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 207 304 9.5E-10 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 Gene3D G3DSA:3.40.50.720 1 207 4.7E-65 T 14-10-2018 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 Gene3D G3DSA:1.10.1040.10 208 333 2.0E-18 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 Pfam PF00378 Enoyl-CoA hydratase/isomerase 489 621 1.2E-11 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 SUPERFAMILY SSF48179 356 458 3.74E-19 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 Gene3D G3DSA:1.10.1040.10 364 435 1.2E-6 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_14045 315cb6a1355e170360eacd931e230f75 793 SUPERFAMILY SSF52096 482 790 2.84E-38 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_14045 315cb6a1355e170360eacd931e230f75 793 Gene3D G3DSA:3.90.226.10 484 670 4.7E-28 T 14-10-2018 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 180 9.3E-41 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 495 556 2.5E-11 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 SUPERFAMILY SSF53738 306 457 6.28E-32 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 SUPERFAMILY SSF53738 29 238 9.03E-47 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 Gene3D G3DSA:3.40.120.10 327 454 1.7E-37 T 14-10-2018 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 SUPERFAMILY SSF55957 470 556 3.27E-15 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 Gene3D G3DSA:3.30.310.50 464 570 1.8E-9 T 14-10-2018 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 317 1.4E-22 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 Gene3D G3DSA:3.40.120.10 209 326 1.1E-21 T 14-10-2018 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 SUPERFAMILY SSF53738 209 319 7.85E-20 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 Gene3D G3DSA:3.40.120.10 33 190 1.6E-46 T 14-10-2018 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 453 1.6E-22 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 1.1E-5 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_14545 9fce37a2a9ce0b116fb193411bf9c5ba 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 1.1E-5 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_18395 b9264b36127ad44f5b7083ccee255493 162 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 3 161 6.7E-55 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I25_18395 b9264b36127ad44f5b7083ccee255493 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 90 103 1.2E-15 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I25_18395 b9264b36127ad44f5b7083ccee255493 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 107 121 1.2E-15 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I25_18395 b9264b36127ad44f5b7083ccee255493 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 122 135 1.2E-15 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I25_18395 b9264b36127ad44f5b7083ccee255493 162 Pfam PF00364 Biotin-requiring enzyme 87 158 8.0E-22 T 14-10-2018 IPR000089 Biotin/lipoyl attachment C2I25_18395 b9264b36127ad44f5b7083ccee255493 162 Gene3D G3DSA:2.40.50.100 83 160 1.6E-28 T 14-10-2018 C2I25_18395 b9264b36127ad44f5b7083ccee255493 162 SUPERFAMILY SSF51230 84 160 3.53E-23 T 14-10-2018 IPR011053 Single hybrid motif C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 497 8.2E-36 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 Gene3D G3DSA:3.30.160.270 393 499 1.4E-10 T 14-10-2018 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 SMART SM00917 368 499 1.6E-31 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 Pfam PF00682 HMGL-like 4 272 1.3E-91 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 Gene3D G3DSA:1.10.238.260 279 392 2.4E-37 T 14-10-2018 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 506 41.092 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 494 1.5E-207 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 Gene3D G3DSA:3.20.20.70 1 275 2.0E-107 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 SUPERFAMILY SSF110921 397 496 6.28E-19 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 SUPERFAMILY SSF51569 1 290 3.22E-91 T 14-10-2018 C2I25_04405 d05e89afece76d4cec500d22de47c4c2 506 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I25_15630 0f1726e4e548933642e213f59971c7fd 337 SUPERFAMILY SSF69572 3 329 6.41E-88 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I25_15630 0f1726e4e548933642e213f59971c7fd 337 Pfam PF00899 ThiF family 5 240 2.4E-63 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I25_15630 0f1726e4e548933642e213f59971c7fd 337 Gene3D G3DSA:3.40.50.720 1 248 1.3E-75 T 14-10-2018 C2I25_04655 85a1871898ff855c72312b48a4f24688 119 Pfam PF07972 NrdI Flavodoxin like 3 110 3.1E-32 T 14-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI C2I25_04655 85a1871898ff855c72312b48a4f24688 119 SUPERFAMILY SSF52218 1 117 1.32E-24 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_04655 85a1871898ff855c72312b48a4f24688 119 Gene3D G3DSA:3.40.50.360 1 119 4.5E-44 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_04655 85a1871898ff855c72312b48a4f24688 119 TIGRFAM TIGR00333 nrdI: nrdI protein 3 117 7.5E-40 T 14-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI C2I25_04655 85a1871898ff855c72312b48a4f24688 119 PIRSF PIRSF005087 1 119 1.3E-41 T 14-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI C2I25_04655 85a1871898ff855c72312b48a4f24688 119 Hamap MF_00128 Protein NrdI [nrdI]. 1 119 26.56 T 14-10-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 SMART SM00766 466 591 1.2E-19 T 14-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 TIGRFAM TIGR01391 dnaG: DNA primase 4 419 1.2E-151 T 14-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Gene3D G3DSA:3.40.1360.10 244 367 9.2E-41 T 14-10-2018 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 255 1.0E-43 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Pfam PF01807 CHC2 zinc finger 6 98 1.0E-37 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Gene3D G3DSA:3.90.580.10 1 102 4.5E-42 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Pfam PF13155 Toprim-like 265 349 8.1E-20 T 14-10-2018 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Gene3D G3DSA:3.90.980.10 114 243 6.1E-47 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 PIRSF PIRSF002811 2 598 3.3E-186 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 SMART SM00400 36 90 3.7E-34 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 SMART SM00493 262 333 1.2E-18 T 14-10-2018 IPR006171 TOPRIM domain C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Gene3D G3DSA:1.10.860.10 463 558 1.9E-21 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Pfam PF10410 DnaB-helicase binding domain of primase 371 420 2.7E-6 T 14-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 Hamap MF_00974 DNA primase [dnaG]. 4 589 29.235 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 SUPERFAMILY SSF57783 4 97 6.29E-36 T 14-10-2018 C2I25_17820 deb6ad802b8952a8c05e6f00881392ed 598 SUPERFAMILY SSF56731 118 425 6.28E-105 T 14-10-2018 C2I25_14880 6360b25d48e6c04a17451a9ea7e9ea66 243 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 87 114 2.3E-10 T 14-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 C2I25_14880 6360b25d48e6c04a17451a9ea7e9ea66 243 SUPERFAMILY SSF109635 2 88 2.88E-15 T 14-10-2018 IPR037187 DksA, N-terminal domain superfamily C2I25_14880 6360b25d48e6c04a17451a9ea7e9ea66 243 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 5 160 5.4E-66 T 14-10-2018 IPR014240 Regulatory protein, YteA family C2I25_14880 6360b25d48e6c04a17451a9ea7e9ea66 243 SUPERFAMILY SSF57716 89 118 3.85E-6 T 14-10-2018 C2I25_14880 6360b25d48e6c04a17451a9ea7e9ea66 243 Gene3D G3DSA:1.20.120.910 1 126 3.9E-34 T 14-10-2018 C2I25_12755 53ee5f7997ff39672c2593f1790f2c3b 335 Gene3D G3DSA:3.40.50.300 6 228 9.4E-26 T 14-10-2018 C2I25_12755 53ee5f7997ff39672c2593f1790f2c3b 335 Pfam PF00005 ABC transporter 18 148 3.4E-9 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_12755 53ee5f7997ff39672c2593f1790f2c3b 335 SUPERFAMILY SSF52540 14 199 2.1E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12755 53ee5f7997ff39672c2593f1790f2c3b 335 Pfam PF04397 LytTr DNA-binding domain 235 333 3.5E-25 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_12755 53ee5f7997ff39672c2593f1790f2c3b 335 SMART SM00850 235 334 5.9E-32 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_12755 53ee5f7997ff39672c2593f1790f2c3b 335 PIRSF PIRSF036612 1 335 1.4E-153 T 14-10-2018 IPR012046 LytTR transcriptional regulator with ABC transporter ATP-binding domain C2I25_12755 53ee5f7997ff39672c2593f1790f2c3b 335 Gene3D G3DSA:2.40.50.40 229 295 8.1E-14 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Gene3D G3DSA:1.10.10.1100 414 469 6.6E-11 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 3.0E-13 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 3.0E-13 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 3.0E-13 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.0E-13 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 554 616 4.1E-10 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 SUPERFAMILY SSF51905 2 191 1.62E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Gene3D G3DSA:3.30.413.10 624 790 1.9E-34 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 8.0E-20 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.0E-20 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 8.0E-20 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 8.0E-20 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 8.0E-20 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 SUPERFAMILY SSF51905 141 305 9.5E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 280 7.2E-58 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Gene3D G3DSA:3.30.390.30 316 395 1.5E-9 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Pfam PF04324 BFD-like [2Fe-2S] binding domain 480 529 1.4E-10 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Pfam PF04324 BFD-like [2Fe-2S] binding domain 414 463 4.0E-15 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00397 Sirohaem Fe-binding site signature 628 646 6.5E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PRINTS PR00397 Sirohaem Fe-binding site signature 671 689 6.5E-6 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 SUPERFAMILY SSF56014 625 761 1.3E-45 T 14-10-2018 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Gene3D G3DSA:3.50.50.60 6 302 3.3E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 789 9.0E-301 T 14-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 671 687 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 PIRSF PIRSF037149 1 800 0.0 T 14-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Gene3D G3DSA:3.50.50.60 114 238 3.3E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 SUPERFAMILY SSF55124 492 615 2.13E-23 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_00965 2c2e502cf0d0823ad816adfcf2939793 801 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 625 758 1.3E-25 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_08300 c31e92598eed41e6694db8b15941a003 262 PIRSF PIRSF039085 18 261 8.3E-115 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 C2I25_08300 c31e92598eed41e6694db8b15941a003 262 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_08300 c31e92598eed41e6694db8b15941a003 262 SUPERFAMILY SSF52540 21 254 6.93E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08300 c31e92598eed41e6694db8b15941a003 262 Gene3D G3DSA:3.40.50.300 19 260 7.1E-78 T 14-10-2018 C2I25_08300 c31e92598eed41e6694db8b15941a003 262 SMART SM00382 46 233 7.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08300 c31e92598eed41e6694db8b15941a003 262 Pfam PF00005 ABC transporter 37 185 5.5E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_01060 fa869376b83aa03d4a27626de30cfad3 320 Gene3D G3DSA:3.40.50.300 22 188 8.1E-46 T 14-10-2018 C2I25_01060 fa869376b83aa03d4a27626de30cfad3 320 SUPERFAMILY SSF52540 8 285 2.06E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01060 fa869376b83aa03d4a27626de30cfad3 320 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 1.2E-63 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 C2I25_01060 fa869376b83aa03d4a27626de30cfad3 320 Gene3D G3DSA:1.10.8.300 202 310 6.1E-37 T 14-10-2018 C2I25_01060 fa869376b83aa03d4a27626de30cfad3 320 PIRSF PIRSF002849 1 315 2.0E-135 T 14-10-2018 C2I25_27325 ed78865be61d40a1bfa5583e49425213 213 SUPERFAMILY SSF82771 21 91 4.05E-8 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I25_27325 ed78865be61d40a1bfa5583e49425213 213 Gene3D G3DSA:3.40.1440.10 8 100 2.0E-12 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 PIRSF PIRSF039088 1 501 5.8E-251 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 SUPERFAMILY SSF47917 372 500 1.62E-46 T 14-10-2018 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 51.655 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 SUPERFAMILY SSF52540 95 370 2.42E-99 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Gene3D G3DSA:2.40.30.20 1 93 2.6E-37 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 SUPERFAMILY SSF50615 10 94 7.46E-31 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 486 7.7E-46 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.2E-20 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Gene3D G3DSA:3.40.50.300 94 371 5.5E-128 T 14-10-2018 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Gene3D G3DSA:1.20.150.20 372 499 6.6E-51 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 3.2E-258 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12645 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 2.0E-73 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 SUPERFAMILY SSF158472 308 358 4.32E-8 T 14-10-2018 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 2.3E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 2.3E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 2.3E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 Gene3D G3DSA:3.30.565.10 448 602 2.0E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 SMART SM00388 381 445 1.3E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 Gene3D G3DSA:1.20.1480.50 269 364 8.7E-12 T 14-10-2018 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 Pfam PF00512 His Kinase A (phospho-acceptor) domain 382 445 1.9E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 SMART SM00387 490 601 6.4E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 Gene3D G3DSA:1.10.287.130 372 447 7.3E-20 T 14-10-2018 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 SUPERFAMILY SSF55874 435 589 5.63E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 492 584 3.0E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 SUPERFAMILY SSF47384 367 445 3.73E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_04095 59a2d68caea280230a0a594aa2b314db 604 SMART SM00304 307 359 5.4E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 Pfam PF00199 Catalase 27 384 5.3E-131 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 Gene3D G3DSA:2.40.180.10 18 459 4.6E-157 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 Pfam PF06628 Catalase-related immune-responsive 394 454 2.7E-14 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 ProSitePatterns PS00438 Catalase proximal active site signature. 54 70 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 SMART SM01060 18 393 3.1E-176 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 PIRSF PIRSF038928 7 390 1.2E-151 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 PIRSF PIRSF038928 383 459 6.3E-10 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 SUPERFAMILY SSF56634 28 456 4.58E-152 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 PRINTS PR00067 Catalase signature 94 112 6.0E-51 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 PRINTS PR00067 Catalase signature 134 152 6.0E-51 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 PRINTS PR00067 Catalase signature 331 357 6.0E-51 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 PRINTS PR00067 Catalase signature 31 54 6.0E-51 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 PRINTS PR00067 Catalase signature 115 132 6.0E-51 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_24460 a11ca1c3cdf3d214e70e73666b3fbc98 459 PRINTS PR00067 Catalase signature 299 326 6.0E-51 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_17630 26915e4c0691d0b471dae0bcb96ecd2c 249 Gene3D G3DSA:3.40.50.150 5 245 8.7E-87 T 14-10-2018 C2I25_17630 26915e4c0691d0b471dae0bcb96ecd2c 249 Gene3D G3DSA:2.20.25.110 143 206 8.7E-87 T 14-10-2018 C2I25_17630 26915e4c0691d0b471dae0bcb96ecd2c 249 SUPERFAMILY SSF53335 3 247 5.18E-53 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_17630 26915e4c0691d0b471dae0bcb96ecd2c 249 Pfam PF13649 Methyltransferase domain 40 135 2.9E-19 T 14-10-2018 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 ProSitePatterns PS00737 Thiolases signature 2. 307 323 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 PIRSF PIRSF000429 1 362 4.3E-113 T 14-10-2018 IPR002155 Thiolase GO:0016747 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 SUPERFAMILY SSF53901 239 359 2.02E-36 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 Gene3D G3DSA:3.40.47.10 121 357 5.0E-121 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 Pfam PF00108 Thiolase, N-terminal domain 5 230 5.7E-48 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 Gene3D G3DSA:3.40.47.10 5 244 5.0E-121 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 359 1.1E-114 T 14-10-2018 IPR002155 Thiolase GO:0016747 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 SUPERFAMILY SSF53901 4 237 1.25E-52 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_21430 27cc0378b2649d3e60e5fc6fdebc9240 363 Pfam PF02803 Thiolase, C-terminal domain 239 360 2.1E-37 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 Pfam PF09383 NIL domain 263 333 1.7E-17 T 14-10-2018 IPR018449 NIL domain C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 Gene3D G3DSA:3.40.50.300 1 232 9.3E-74 T 14-10-2018 C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 SUPERFAMILY SSF52540 1 240 2.81E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 SMART SM00930 260 335 5.2E-23 T 14-10-2018 IPR018449 NIL domain C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 Pfam PF00005 ABC transporter 21 169 2.3E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 SUPERFAMILY SSF55021 248 333 2.4E-18 T 14-10-2018 C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 Gene3D G3DSA:3.30.70.260 233 335 1.0E-26 T 14-10-2018 C2I25_10630 6508385dfe111e357fcdcb1a80fafc5f 346 SMART SM00382 30 218 8.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 452 474 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 136 153 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 102 120 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 81 100 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 160 178 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 430 446 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 207 224 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 365 383 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 252 271 2.5E-49 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 PIRSF PIRSF016599 2 487 1.3E-190 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 Pfam PF01546 Peptidase family M20/M25/M40 74 472 7.5E-19 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_27490 47f551b7169c3650b339833a067d4976 489 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 9 483 8.4E-178 T 14-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I25_27490 47f551b7169c3650b339833a067d4976 489 SUPERFAMILY SSF53187 13 482 1.63E-53 T 14-10-2018 C2I25_27490 47f551b7169c3650b339833a067d4976 489 Gene3D G3DSA:3.40.630.10 345 487 5.7E-20 T 14-10-2018 C2I25_27490 47f551b7169c3650b339833a067d4976 489 SUPERFAMILY SSF55031 213 302 3.59E-5 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_27490 47f551b7169c3650b339833a067d4976 489 Gene3D G3DSA:3.40.630.10 2 269 2.3E-55 T 14-10-2018 C2I25_27490 47f551b7169c3650b339833a067d4976 489 Pfam PF07687 Peptidase dimerisation domain 213 292 3.4E-9 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 Pfam PF08264 Anticodon-binding domain of tRNA 416 510 1.3E-8 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 Pfam PF09334 tRNA synthetases class I (M) 4 393 7.5E-139 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 Gene3D G3DSA:2.20.28.20 137 170 1.2E-147 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 Gene3D G3DSA:1.10.730.10 376 538 6.2E-40 T 14-10-2018 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 SUPERFAMILY SSF52374 4 380 8.73E-92 T 14-10-2018 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 528 6.4E-159 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 Gene3D G3DSA:3.40.50.620 3 375 1.2E-147 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 SUPERFAMILY SSF57770 137 170 4.19E-8 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 287 302 1.2E-18 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 37 51 1.2E-18 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 1.2E-18 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 85 96 1.2E-18 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 380 391 1.2E-18 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 1.2E-18 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 SUPERFAMILY SSF47323 385 537 1.63E-37 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 538 38.491 T 14-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_13890 3af74787788eb3c2c93544c1e8bfb6b5 544 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_25240 3802da377f96055608183d6e062aa103 250 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 2 245 58.36 T 14-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 C2I25_25240 3802da377f96055608183d6e062aa103 250 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 62 236 7.4E-48 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 C2I25_25240 3802da377f96055608183d6e062aa103 250 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 65 230 2.3E-54 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 C2I25_18250 7f005195a9a6fd2c6a64a0c3c4c48584 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 1.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_18250 7f005195a9a6fd2c6a64a0c3c4c48584 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 1.2E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_18250 7f005195a9a6fd2c6a64a0c3c4c48584 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 49 4.0E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_18250 7f005195a9a6fd2c6a64a0c3c4c48584 191 Gene3D G3DSA:1.10.357.10 51 189 6.8E-17 T 14-10-2018 C2I25_18250 7f005195a9a6fd2c6a64a0c3c4c48584 191 Gene3D G3DSA:1.10.10.60 1 50 1.1E-15 T 14-10-2018 C2I25_18250 7f005195a9a6fd2c6a64a0c3c4c48584 191 SUPERFAMILY SSF46689 2 63 2.28E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 1.4E-218 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 SMART SM01192 139 428 8.5E-227 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 366 383 1.5E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 107 123 1.5E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 314 325 1.5E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 337 351 1.5E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 37 51 1.5E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 161 174 1.5E-46 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 SMART SM01193 4 134 4.3E-101 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 PIRSF PIRSF001400 1 428 4.5E-198 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 ProSitePatterns PS00164 Enolase signature. 337 350 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 SUPERFAMILY SSF51604 138 428 2.4E-133 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 SUPERFAMILY SSF54826 3 138 3.98E-61 T 14-10-2018 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 Gene3D G3DSA:3.20.20.120 128 431 2.5E-139 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 Hamap MF_00318 Enolase [eno]. 2 414 46.27 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 3.4E-142 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 Gene3D G3DSA:3.30.390.10 1 127 2.2E-59 T 14-10-2018 IPR029017 Enolase-like, N-terminal C2I25_13550 39ac911f45dcc424720dd7e6f84f9b0d 431 Pfam PF03952 Enolase, N-terminal domain 4 134 2.0E-62 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_16745 f1adeede25b2b3a2ef9baec68f200b34 253 SUPERFAMILY SSF54292 2 111 3.13E-22 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I25_16745 f1adeede25b2b3a2ef9baec68f200b34 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 154 165 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I25_16745 f1adeede25b2b3a2ef9baec68f200b34 253 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 117 8.7E-29 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16745 f1adeede25b2b3a2ef9baec68f200b34 253 SUPERFAMILY SSF46548 113 238 2.44E-26 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I25_16745 f1adeede25b2b3a2ef9baec68f200b34 253 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 233 1.2E-40 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16745 f1adeede25b2b3a2ef9baec68f200b34 253 Gene3D G3DSA:3.10.20.30 1 111 1.1E-29 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_16745 f1adeede25b2b3a2ef9baec68f200b34 253 Pfam PF13183 4Fe-4S dicluster domain 150 225 4.2E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_16745 f1adeede25b2b3a2ef9baec68f200b34 253 Gene3D G3DSA:1.10.1060.10 113 247 1.2E-28 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 541 661 3.8E-48 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 Pfam PF00367 phosphotransferase system, EIIB 442 475 3.4E-12 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 603 615 - T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 Pfam PF02378 Phosphotransferase system, EIIC 13 355 5.0E-100 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 515 1.6E-270 T 14-10-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0016021|GO:1904659 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 540 663 3.6E-53 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 Gene3D G3DSA:3.30.1360.60 436 516 6.9E-27 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 SUPERFAMILY SSF55604 442 513 6.41E-20 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 64 366 7.7E-88 T 14-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 453 470 - T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 Gene3D G3DSA:2.70.70.10 527 687 2.2E-64 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 SUPERFAMILY SSF51261 533 683 4.19E-57 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_19220 6f3a4efabaee07dc2cfcd46828699b45 687 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 415 499 1.4E-20 T 14-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 Gene3D G3DSA:1.25.40.340 366 583 1.7E-55 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 Gene3D G3DSA:3.30.1180.20 183 328 3.8E-52 T 14-10-2018 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 327 4.0E-136 T 14-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 SUPERFAMILY SSF82549 1 329 2.59E-121 T 14-10-2018 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 Pfam PF02733 Dak1 domain 18 326 6.0E-126 T 14-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 Pfam PF02734 DAK2 domain 398 579 3.6E-52 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 SMART SM01120 397 580 1.2E-58 T 14-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 SUPERFAMILY SSF101473 356 580 1.31E-45 T 14-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 Gene3D G3DSA:3.40.50.10440 13 182 4.4E-64 T 14-10-2018 C2I25_06535 433105da7dec5f398aa711b1e2d62037 583 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 376 579 2.5E-41 T 14-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 C2I25_13685 5933422f48842070252954f4d176a663 79 Pfam PF13135 Protein of unknown function (DUF3947) 2 79 2.5E-30 T 14-10-2018 IPR025039 Protein of unknown function DUF3947 C2I25_05135 35eef760964243a26548b845fd815210 513 SUPERFAMILY SSF55469 417 501 6.54E-9 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_05135 35eef760964243a26548b845fd815210 513 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 59 227 1.6E-54 T 14-10-2018 IPR020051 SagB-type dehydrogenase domain C2I25_05135 35eef760964243a26548b845fd815210 513 Gene3D G3DSA:3.40.109.10 284 502 2.4E-22 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_05135 35eef760964243a26548b845fd815210 513 Pfam PF00881 Nitroreductase family 410 499 8.2E-8 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_05135 35eef760964243a26548b845fd815210 513 Gene3D G3DSA:3.40.109.10 22 283 4.6E-55 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_28030 abba4f6e958393dec32df1d979b723bf 317 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 7 306 8.4E-44 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain C2I25_28030 abba4f6e958393dec32df1d979b723bf 317 Gene3D G3DSA:3.90.245.10 6 317 1.5E-106 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_28030 abba4f6e958393dec32df1d979b723bf 317 SUPERFAMILY SSF53590 5 313 5.49E-80 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_22905 457d7663145aa77f9ee6eb0e938ebfd0 182 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 182 1.5E-5 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22905 457d7663145aa77f9ee6eb0e938ebfd0 182 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 1.5E-5 T 14-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22905 457d7663145aa77f9ee6eb0e938ebfd0 182 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 8 182 8.6E-49 T 14-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I25_22905 457d7663145aa77f9ee6eb0e938ebfd0 182 Gene3D G3DSA:3.40.50.720 1 182 5.5E-49 T 14-10-2018 C2I25_22905 457d7663145aa77f9ee6eb0e938ebfd0 182 SUPERFAMILY SSF51735 2 182 9.45E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_17605 8ab1bff932a2071391b8180096991316 277 Gene3D G3DSA:3.40.50.720 101 241 7.2E-100 T 14-10-2018 C2I25_17605 8ab1bff932a2071391b8180096991316 277 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 1.3E-32 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 C2I25_17605 8ab1bff932a2071391b8180096991316 277 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 273 36.46 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 C2I25_17605 8ab1bff932a2071391b8180096991316 277 Gene3D G3DSA:3.40.50.10860 5 262 7.2E-100 T 14-10-2018 C2I25_17605 8ab1bff932a2071391b8180096991316 277 SUPERFAMILY SSF51735 102 274 9.86E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_17605 8ab1bff932a2071391b8180096991316 277 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 116 209 4.8E-12 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase C2I25_17605 8ab1bff932a2071391b8180096991316 277 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 275 7.5E-94 T 14-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 C2I25_17605 8ab1bff932a2071391b8180096991316 277 SUPERFAMILY SSF53223 3 101 3.8E-37 T 14-10-2018 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 Gene3D G3DSA:3.40.50.2300 161 291 8.5E-94 T 14-10-2018 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 SMART SM00354 2 72 1.2E-39 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 TIGRFAM TIGR01481 ccpA: catabolite control protein A 1 332 9.8E-166 T 14-10-2018 IPR006377 Catabolite control protein A GO:0006355 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 SUPERFAMILY SSF53822 62 332 2.55E-90 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 Gene3D G3DSA:1.10.260.40 1 60 2.8E-29 T 14-10-2018 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 Gene3D G3DSA:3.40.50.2300 63 310 8.5E-94 T 14-10-2018 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 2.8E-19 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 Pfam PF13377 Periplasmic binding protein-like domain 170 331 4.3E-37 T 14-10-2018 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 SUPERFAMILY SSF47413 2 60 8.44E-20 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.3E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.3E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_15895 3d18046ad35b71aaa00bea67191a6752 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 14-10-2018 C2I25_17740 7ce1cc738a9e071bbc2669590770ab00 147 Pfam PF09424 Yqey-like protein 6 146 1.5E-53 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 C2I25_17740 7ce1cc738a9e071bbc2669590770ab00 147 Gene3D G3DSA:1.10.1510.10 1 90 4.6E-29 T 14-10-2018 C2I25_17740 7ce1cc738a9e071bbc2669590770ab00 147 SUPERFAMILY SSF89095 1 146 1.83E-42 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 C2I25_17740 7ce1cc738a9e071bbc2669590770ab00 147 Gene3D G3DSA:1.10.10.410 91 147 7.6E-24 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal C2I25_10280 8801be19bac24b5fb3c4aeee9a84978b 190 SUPERFAMILY SSF144091 14 183 2.88E-37 T 14-10-2018 C2I25_10280 8801be19bac24b5fb3c4aeee9a84978b 190 Pfam PF01694 Rhomboid family 43 182 1.6E-31 T 14-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 C2I25_10280 8801be19bac24b5fb3c4aeee9a84978b 190 Gene3D G3DSA:1.20.1540.10 3 188 2.6E-34 T 14-10-2018 IPR035952 Rhomboid-like superfamily C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 Pfam PF00248 Aldo/keto reductase family 30 263 3.9E-52 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 Gene3D G3DSA:3.20.20.100 3 277 1.5E-123 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 SUPERFAMILY SSF51430 9 271 2.88E-95 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 PIRSF PIRSF000097 3 274 4.6E-91 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 45 62 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 PRINTS PR00069 Aldo-keto reductase signature 127 144 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 PRINTS PR00069 Aldo-keto reductase signature 97 115 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 PRINTS PR00069 Aldo-keto reductase signature 198 222 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 PRINTS PR00069 Aldo-keto reductase signature 41 65 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_10530 460025aa86b03fef0053b9c53808fe08 277 PRINTS PR00069 Aldo-keto reductase signature 161 190 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_03785 61a3c4ca03785def2693a12e00d6f10e 224 PIRSF PIRSF000032 2 224 9.2E-103 T 14-10-2018 C2I25_03785 61a3c4ca03785def2693a12e00d6f10e 224 Gene3D G3DSA:1.20.810.10 1 224 3.1E-89 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 C2I25_03785 61a3c4ca03785def2693a12e00d6f10e 224 SUPERFAMILY SSF81342 6 224 1.01E-61 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 C2I25_03785 61a3c4ca03785def2693a12e00d6f10e 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 5.1E-49 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 414 6.6E-27 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 Gene3D G3DSA:3.40.50.20 2 93 9.2E-36 T 14-10-2018 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.8E-35 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 SMART SM01209 101 293 3.6E-133 T 14-10-2018 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 Gene3D G3DSA:3.30.1490.20 119 188 1.6E-29 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 SUPERFAMILY SSF52440 1 101 7.63E-35 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 SUPERFAMILY SSF56059 102 312 2.12E-62 T 14-10-2018 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 SUPERFAMILY SSF51246 324 416 9.42E-28 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 SMART SM01210 325 416 9.6E-44 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 42.549 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 14-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 1.2E-84 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 Gene3D G3DSA:3.30.470.20 189 324 1.9E-56 T 14-10-2018 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 416 1.5E-169 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09885 6b529e8ea8e1b63a57a1b9e0936cfaf0 423 Gene3D G3DSA:3.90.600.10 325 422 2.2E-32 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_13555 d84f09e1e48cbdc9d970e5fe90baf938 316 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 305 2.0E-58 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain C2I25_13555 d84f09e1e48cbdc9d970e5fe90baf938 316 SUPERFAMILY SSF53590 1 311 5.49E-75 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_13555 d84f09e1e48cbdc9d970e5fe90baf938 316 Gene3D G3DSA:3.90.245.10 1 314 2.6E-67 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 2.3E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.3E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 2.3E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 2.3E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 187 3.2E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 186 5.0E-16 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 188 1.4E-36 T 14-10-2018 C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 Gene3D G3DSA:3.40.50.1000 4 195 1.9E-48 T 14-10-2018 IPR023214 HAD superfamily C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 Gene3D G3DSA:1.10.150.520 16 92 1.9E-48 T 14-10-2018 C2I25_15285 aef0fcfe9b208c8983a446c2df08a18c 223 SUPERFAMILY SSF56784 1 216 1.17E-42 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_12625 951194ed8efecf005b120b636888d0d1 239 Pfam PF00119 ATP synthase A chain 20 231 4.8E-58 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 14 234 1.6E-48 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 PRINTS PR00123 ATP synthase A subunit signature 149 164 1.4E-18 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 PRINTS PR00123 ATP synthase A subunit signature 165 187 1.4E-18 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 PRINTS PR00123 ATP synthase A subunit signature 218 233 1.4E-18 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 PRINTS PR00123 ATP synthase A subunit signature 77 93 1.4E-18 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 Gene3D G3DSA:1.20.120.220 70 239 5.1E-42 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 SUPERFAMILY SSF81336 69 231 8.5E-42 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 Hamap MF_01393 ATP synthase subunit a [atpB]. 7 238 13.84 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_12625 951194ed8efecf005b120b636888d0d1 239 ProSitePatterns PS00449 ATP synthase a subunit signature. 168 177 - T 14-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I25_07125 83f42a43253571e26b986dbda2f60df0 171 Pfam PF01965 DJ-1/PfpI family 3 167 2.4E-52 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I25_07125 83f42a43253571e26b986dbda2f60df0 171 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 170 9.3E-57 T 14-10-2018 IPR006286 Deglycase PfpI C2I25_07125 83f42a43253571e26b986dbda2f60df0 171 Gene3D G3DSA:3.40.50.880 1 171 4.1E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_07125 83f42a43253571e26b986dbda2f60df0 171 SUPERFAMILY SSF52317 1 170 2.37E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_18265 e1ab3bb6a5116180a03eb4f56b22b498 127 SUPERFAMILY SSF52821 11 121 1.83E-33 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_18265 e1ab3bb6a5116180a03eb4f56b22b498 127 Pfam PF00581 Rhodanese-like domain 43 121 7.8E-19 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_18265 e1ab3bb6a5116180a03eb4f56b22b498 127 SMART SM00450 31 126 2.6E-26 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_18265 e1ab3bb6a5116180a03eb4f56b22b498 127 Gene3D G3DSA:3.40.250.10 32 127 1.7E-28 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_08410 4a5fa3217d2fec199523dc18e3ada0bf 334 SUPERFAMILY SSF81345 5 329 2.22E-81 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_08410 4a5fa3217d2fec199523dc18e3ada0bf 334 Pfam PF01032 FecCD transport family 20 329 5.3E-93 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_08410 4a5fa3217d2fec199523dc18e3ada0bf 334 Gene3D G3DSA:1.10.3470.10 6 333 2.2E-93 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 PIRSF PIRSF004749 2 184 2.3E-47 T 14-10-2018 IPR023635 Peptide deformylase C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 SUPERFAMILY SSF56420 2 178 8.24E-62 T 14-10-2018 IPR036821 Peptide deformylase superfamily C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 177 1.8E-50 T 14-10-2018 IPR023635 Peptide deformylase C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 PRINTS PR01576 Peptide deformylase signature 121 139 6.6E-33 T 14-10-2018 IPR023635 Peptide deformylase C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 PRINTS PR01576 Peptide deformylase signature 47 76 6.6E-33 T 14-10-2018 IPR023635 Peptide deformylase C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 PRINTS PR01576 Peptide deformylase signature 140 169 6.6E-33 T 14-10-2018 IPR023635 Peptide deformylase C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 PRINTS PR01576 Peptide deformylase signature 108 119 6.6E-33 T 14-10-2018 IPR023635 Peptide deformylase C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 Gene3D G3DSA:3.90.45.10 1 184 2.1E-72 T 14-10-2018 IPR036821 Peptide deformylase superfamily C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 28.08 T 14-10-2018 IPR023635 Peptide deformylase C2I25_19620 5bfca35a4be59cdc29c6524c1147aa2c 184 Pfam PF01327 Polypeptide deformylase 4 171 7.6E-46 T 14-10-2018 IPR023635 Peptide deformylase C2I25_06005 9992f00c18639964d988682c962100ad 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 3.2E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06005 9992f00c18639964d988682c962100ad 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_06005 9992f00c18639964d988682c962100ad 190 Gene3D G3DSA:1.10.10.60 4 51 2.8E-17 T 14-10-2018 C2I25_06005 9992f00c18639964d988682c962100ad 190 SUPERFAMILY SSF48498 76 189 4.14E-14 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_06005 9992f00c18639964d988682c962100ad 190 SUPERFAMILY SSF46689 4 78 2.96E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_06005 9992f00c18639964d988682c962100ad 190 Gene3D G3DSA:1.10.357.10 52 190 8.3E-20 T 14-10-2018 C2I25_06005 9992f00c18639964d988682c962100ad 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 6.5E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06005 9992f00c18639964d988682c962100ad 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 6.5E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 Gene3D G3DSA:3.40.710.10 29 306 1.1E-91 T 14-10-2018 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 SMART SM00936 306 408 2.6E-18 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 285 1.7E-83 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 Gene3D G3DSA:2.60.410.10 307 408 2.7E-18 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 1.5E-14 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 1.5E-14 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 1.5E-14 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 306 408 5.5E-16 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 SUPERFAMILY SSF56601 4 306 3.03E-78 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_11580 bfcfbe65f57cfafe66317a201fdd5528 438 SUPERFAMILY SSF69189 298 387 5.1E-17 T 14-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_14520 fb20687ee2b21cc5707d8226bbb56e96 168 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_14520 fb20687ee2b21cc5707d8226bbb56e96 168 Gene3D G3DSA:3.90.79.10 9 147 1.7E-25 T 14-10-2018 C2I25_14520 fb20687ee2b21cc5707d8226bbb56e96 168 SUPERFAMILY SSF55811 6 129 1.76E-26 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_14520 fb20687ee2b21cc5707d8226bbb56e96 168 PRINTS PR00502 NUDIX hydrolase family signature 36 50 2.7E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_14520 fb20687ee2b21cc5707d8226bbb56e96 168 PRINTS PR00502 NUDIX hydrolase family signature 50 65 2.7E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_14520 fb20687ee2b21cc5707d8226bbb56e96 168 Pfam PF00293 NUDIX domain 9 118 2.3E-17 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_02725 235acb00a25b99b62be84dad88bd97b3 270 Gene3D G3DSA:3.30.2010.10 87 157 1.7E-6 T 14-10-2018 C2I25_02725 235acb00a25b99b62be84dad88bd97b3 270 Pfam PF05569 BlaR1 peptidase M56 52 232 5.4E-13 T 14-10-2018 IPR008756 Peptidase M56 C2I25_20555 6b18ea176f28fddfd17571d7e7b84b9e 361 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 43 348 1.8E-86 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 C2I25_20555 6b18ea176f28fddfd17571d7e7b84b9e 361 Gene3D G3DSA:3.40.50.2300 147 343 1.2E-109 T 14-10-2018 C2I25_20555 6b18ea176f28fddfd17571d7e7b84b9e 361 Gene3D G3DSA:3.40.50.2300 44 307 1.2E-109 T 14-10-2018 C2I25_20555 6b18ea176f28fddfd17571d7e7b84b9e 361 SUPERFAMILY SSF53822 54 267 3.85E-15 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_20790 dbe770964e1796f47c935f2314bf56fa 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.2E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_20790 dbe770964e1796f47c935f2314bf56fa 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 1.2E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_20790 dbe770964e1796f47c935f2314bf56fa 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 1.2E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_20790 dbe770964e1796f47c935f2314bf56fa 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 1.2E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_20790 dbe770964e1796f47c935f2314bf56fa 271 Gene3D G3DSA:3.40.50.1820 3 268 1.4E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_20790 dbe770964e1796f47c935f2314bf56fa 271 Pfam PF12146 Serine aminopeptidase, S33 21 131 1.2E-8 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 C2I25_20790 dbe770964e1796f47c935f2314bf56fa 271 SUPERFAMILY SSF53474 4 263 1.32E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_01885 384c3f8d16f289a05f4808af0e3421a7 188 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I25_01885 384c3f8d16f289a05f4808af0e3421a7 188 SUPERFAMILY SSF51161 18 178 6.02E-30 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_01885 384c3f8d16f289a05f4808af0e3421a7 188 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 119 150 6.9E-4 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_01885 384c3f8d16f289a05f4808af0e3421a7 188 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 37 66 2.6E-4 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_01885 384c3f8d16f289a05f4808af0e3421a7 188 Gene3D G3DSA:2.160.10.10 1 171 1.6E-46 T 14-10-2018 C2I25_21310 3e5a08fc25d723208a2ec76df8f68735 70 Pfam PF05532 CsbD-like 10 61 6.6E-18 T 14-10-2018 IPR008462 CsbD-like domain C2I25_21310 3e5a08fc25d723208a2ec76df8f68735 70 Gene3D G3DSA:1.10.1470.10 9 69 1.4E-7 T 14-10-2018 IPR036629 YjbJ superfamily C2I25_21310 3e5a08fc25d723208a2ec76df8f68735 70 SUPERFAMILY SSF69047 9 63 2.48E-12 T 14-10-2018 IPR036629 YjbJ superfamily C2I25_01580 34840e675015d395213d45368aaecf5f 349 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 66 316 3.8E-50 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 C2I25_01580 34840e675015d395213d45368aaecf5f 349 Pfam PF03193 RsgA GTPase 86 261 1.0E-49 T 14-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 C2I25_01580 34840e675015d395213d45368aaecf5f 349 SUPERFAMILY SSF50249 26 90 6.85E-8 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_01580 34840e675015d395213d45368aaecf5f 349 SUPERFAMILY SSF52540 103 322 2.37E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01580 34840e675015d395213d45368aaecf5f 349 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 24 324 33.016 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 C2I25_01580 34840e675015d395213d45368aaecf5f 349 Gene3D G3DSA:3.40.50.300 89 260 3.8E-47 T 14-10-2018 C2I25_01580 34840e675015d395213d45368aaecf5f 349 Gene3D G3DSA:1.10.40.50 262 333 6.8E-22 T 14-10-2018 C2I25_27505 f27ffe7f2928994b5ec5467f212f6596 326 SUPERFAMILY SSF140453 3 93 3.4E-12 T 14-10-2018 IPR036689 ESAT-6-like superfamily C2I25_27505 f27ffe7f2928994b5ec5467f212f6596 326 Gene3D G3DSA:1.10.287.850 1 94 1.4E-28 T 14-10-2018 C2I25_27505 f27ffe7f2928994b5ec5467f212f6596 326 Pfam PF06013 Proteins of 100 residues with WXG 3 86 6.0E-14 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_27505 f27ffe7f2928994b5ec5467f212f6596 326 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 4.7E-17 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 637 655 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Gene3D G3DSA:1.10.1780.10 1 151 3.6E-36 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Gene3D G3DSA:3.40.50.300 152 345 7.1E-75 T 14-10-2018 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 SUPERFAMILY SSF52540 552 864 2.12E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 774 854 6.4E-25 T 14-10-2018 IPR019489 Clp ATPase, C-terminal C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Gene3D G3DSA:3.40.50.300 346 550 1.5E-70 T 14-10-2018 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Gene3D G3DSA:1.10.8.60 774 866 2.9E-29 T 14-10-2018 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 2.0E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 714 728 2.0E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 2.0E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 2.0E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 SUPERFAMILY SSF81923 4 158 3.14E-41 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 SMART SM00382 603 754 1.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 SMART SM00382 201 347 1.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 602 768 1.0E-56 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 339 1.1E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 297 309 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 SMART SM01086 774 863 1.9E-36 T 14-10-2018 IPR019489 Clp ATPase, C-terminal C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 SUPERFAMILY SSF52540 160 551 2.43E-96 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Gene3D G3DSA:3.40.50.300 556 772 2.2E-88 T 14-10-2018 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 863 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.0E-16 T 14-10-2018 IPR004176 Clp, N-terminal C2I25_05555 65443909a57f95411b1ccd2916d6e23a 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 148 8.2E-11 T 14-10-2018 IPR004176 Clp, N-terminal C2I25_15840 39b824102ec47452fff7dd897a501b1d 301 SUPERFAMILY SSF103481 189 286 1.28E-7 T 14-10-2018 C2I25_15840 39b824102ec47452fff7dd897a501b1d 301 SUPERFAMILY SSF103481 38 141 1.57E-16 T 14-10-2018 C2I25_15840 39b824102ec47452fff7dd897a501b1d 301 Pfam PF00892 EamA-like transporter family 153 287 2.0E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_15840 39b824102ec47452fff7dd897a501b1d 301 Pfam PF00892 EamA-like transporter family 9 139 7.2E-25 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_10965 9449923bc88e8a1500a28c380f65608d 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 38.224 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10965 9449923bc88e8a1500a28c380f65608d 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 6.9E-84 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10965 9449923bc88e8a1500a28c380f65608d 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 7.6E-74 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 C2I25_10965 9449923bc88e8a1500a28c380f65608d 207 Gene3D G3DSA:3.40.1370.10 2 207 2.2E-85 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_10965 9449923bc88e8a1500a28c380f65608d 207 SUPERFAMILY SSF52166 1 206 4.71E-86 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_10320 a7ab615b11bf9520885e3e5a1b1364a4 318 SUPERFAMILY SSF56529 77 299 7.98E-70 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I25_10320 a7ab615b11bf9520885e3e5a1b1364a4 318 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 80 298 2.4E-64 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 C2I25_10320 a7ab615b11bf9520885e3e5a1b1364a4 318 Gene3D G3DSA:3.90.850.10 25 301 2.9E-88 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I25_21225 c2373c5412e8064e7e84b4da38629634 505 Gene3D G3DSA:1.20.200.10 196 500 1.2E-122 T 14-10-2018 C2I25_21225 c2373c5412e8064e7e84b4da38629634 505 SUPERFAMILY SSF48557 1 493 4.08E-194 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I25_21225 c2373c5412e8064e7e84b4da38629634 505 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 44.761 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21225 c2373c5412e8064e7e84b4da38629634 505 Gene3D G3DSA:1.10.275.10 1 195 3.0E-68 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I25_21225 c2373c5412e8064e7e84b4da38629634 505 Pfam PF00221 Aromatic amino acid lyase 9 466 8.3E-195 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 C2I25_21225 c2373c5412e8064e7e84b4da38629634 505 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 14-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 C2I25_21225 c2373c5412e8064e7e84b4da38629634 505 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 493 8.3E-215 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_14215 a7f5b57c50b44ef406443f0c823f5a0d 463 Gene3D G3DSA:3.60.21.10 1 271 4.6E-46 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_14215 a7f5b57c50b44ef406443f0c823f5a0d 463 PIRSF PIRSF036361 1 459 1.9E-160 T 14-10-2018 IPR011240 Phosphoesterase-related protein YunD C2I25_14215 a7f5b57c50b44ef406443f0c823f5a0d 463 SUPERFAMILY SSF56300 1 247 4.6E-54 T 14-10-2018 C2I25_14215 a7f5b57c50b44ef406443f0c823f5a0d 463 Pfam PF02872 5'-nucleotidase, C-terminal domain 284 421 3.2E-13 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_14215 a7f5b57c50b44ef406443f0c823f5a0d 463 Gene3D G3DSA:3.90.780.10 277 462 1.9E-12 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_14215 a7f5b57c50b44ef406443f0c823f5a0d 463 SUPERFAMILY SSF55816 278 457 3.27E-25 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I25_14215 a7f5b57c50b44ef406443f0c823f5a0d 463 Pfam PF00149 Calcineurin-like phosphoesterase 3 200 3.5E-7 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_12825 496265474847173c2404c6d8a209703a 405 Gene3D G3DSA:3.90.1150.10 279 405 3.9E-25 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_12825 496265474847173c2404c6d8a209703a 405 SUPERFAMILY SSF53383 8 404 5.42E-98 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_12825 496265474847173c2404c6d8a209703a 405 PIRSF PIRSF000390 5 405 5.0E-84 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase C2I25_12825 496265474847173c2404c6d8a209703a 405 Gene3D G3DSA:3.40.640.10 1 277 1.6E-87 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_12825 496265474847173c2404c6d8a209703a 405 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 398 1.2E-88 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase C2I25_09480 4e6b6435a1b5d733e0cee8b5e44933e4 471 Pfam PF13520 Amino acid permease 7 443 2.1E-76 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_09480 4e6b6435a1b5d733e0cee8b5e44933e4 471 Gene3D G3DSA:1.20.1740.10 2 465 1.8E-67 T 14-10-2018 C2I25_09480 4e6b6435a1b5d733e0cee8b5e44933e4 471 PIRSF PIRSF006060 1 470 1.3E-56 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_09480 4e6b6435a1b5d733e0cee8b5e44933e4 471 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 5 471 2.9E-222 T 14-10-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 C2I25_09480 4e6b6435a1b5d733e0cee8b5e44933e4 471 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 4 471 2.4E-188 T 14-10-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 C2I25_16600 9a317754a8595bd5c38382ec397174a8 256 SMART SM00382 26 215 8.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_16600 9a317754a8595bd5c38382ec397174a8 256 Pfam PF00005 ABC transporter 17 165 3.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_16600 9a317754a8595bd5c38382ec397174a8 256 Gene3D G3DSA:3.40.50.300 1 253 2.4E-65 T 14-10-2018 C2I25_16600 9a317754a8595bd5c38382ec397174a8 256 SUPERFAMILY SSF52540 1 224 9.06E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16600 9a317754a8595bd5c38382ec397174a8 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_25780 bb36dfcac31cc4448aa85dbf507e757b 259 SUPERFAMILY SSF54001 4 248 1.25E-40 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_25780 bb36dfcac31cc4448aa85dbf507e757b 259 Gene3D G3DSA:3.30.2140.20 4 241 2.5E-15 T 14-10-2018 C2I25_25780 bb36dfcac31cc4448aa85dbf507e757b 259 Pfam PF00797 N-acetyltransferase 23 151 1.2E-5 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_14845 4e8acdbb47ae2883de06306265c0da70 802 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 5 795 0.0 T 14-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 C2I25_14845 4e8acdbb47ae2883de06306265c0da70 802 Gene3D G3DSA:3.40.50.2000 461 788 0.0 T 14-10-2018 C2I25_14845 4e8acdbb47ae2883de06306265c0da70 802 SUPERFAMILY SSF53756 4 795 3.37E-301 T 14-10-2018 C2I25_14845 4e8acdbb47ae2883de06306265c0da70 802 PIRSF PIRSF000460 3 801 2.8E-234 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 C2I25_14845 4e8acdbb47ae2883de06306265c0da70 802 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 639 651 - T 14-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 C2I25_14845 4e8acdbb47ae2883de06306265c0da70 802 Gene3D G3DSA:3.40.50.2000 15 795 0.0 T 14-10-2018 C2I25_14845 4e8acdbb47ae2883de06306265c0da70 802 Pfam PF00343 Carbohydrate phosphorylase 93 795 0.0 T 14-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 C2I25_00140 6f6ff84d586beafe8f52b985b0a5d22c 284 SUPERFAMILY SSF46689 8 80 2.69E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_00140 6f6ff84d586beafe8f52b985b0a5d22c 284 SUPERFAMILY SSF53697 94 281 5.75E-47 T 14-10-2018 C2I25_00140 6f6ff84d586beafe8f52b985b0a5d22c 284 Gene3D G3DSA:1.10.10.10 3 84 1.7E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_00140 6f6ff84d586beafe8f52b985b0a5d22c 284 Gene3D G3DSA:3.40.50.10490 98 283 8.8E-54 T 14-10-2018 C2I25_00140 6f6ff84d586beafe8f52b985b0a5d22c 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 78 3.9E-20 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 C2I25_00140 6f6ff84d586beafe8f52b985b0a5d22c 284 Pfam PF01380 SIS domain 130 258 3.7E-24 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I25_09645 381e7ce9fecc771d086605da29cb6ec6 201 Pfam PF13679 Methyltransferase domain 46 103 1.2E-7 T 14-10-2018 IPR025714 Methyltransferase domain C2I25_09645 381e7ce9fecc771d086605da29cb6ec6 201 Gene3D G3DSA:3.40.50.150 24 198 8.4E-16 T 14-10-2018 C2I25_09645 381e7ce9fecc771d086605da29cb6ec6 201 SUPERFAMILY SSF53335 24 154 3.01E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_20145 c3cca543446ff4e5da6aa879e24955d4 87 Hamap MF_01503 UPF0296 protein . 3 86 28.228 T 14-10-2018 IPR007169 Extracellular matrix regulatory protein A C2I25_20145 c3cca543446ff4e5da6aa879e24955d4 87 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 6 78 2.0E-36 T 14-10-2018 IPR007169 Extracellular matrix regulatory protein A C2I25_20145 c3cca543446ff4e5da6aa879e24955d4 87 Pfam PF04025 Domain of unknown function (DUF370) 5 77 5.3E-36 T 14-10-2018 IPR007169 Extracellular matrix regulatory protein A C2I25_04345 9f6a989d0a0e04ad40a966e4f65d2e94 107 Gene3D G3DSA:1.10.287.1080 1 95 3.6E-33 T 14-10-2018 C2I25_04345 9f6a989d0a0e04ad40a966e4f65d2e94 107 SUPERFAMILY SSF101386 8 93 4.94E-25 T 14-10-2018 C2I25_04345 9f6a989d0a0e04ad40a966e4f65d2e94 107 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 8 92 6.7E-20 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 C2I25_04345 9f6a989d0a0e04ad40a966e4f65d2e94 107 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 88 20.795 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 C2I25_04345 9f6a989d0a0e04ad40a966e4f65d2e94 107 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 6 87 4.3E-33 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 105 116 2.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 2.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 2.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 SUPERFAMILY SSF51735 15 265 1.06E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 165 193 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 2.7E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 2.7E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 2.7E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 2.7E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 2.7E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 116 2.7E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 265 6.9E-43 T 14-10-2018 C2I25_10640 de7412f8916e7e2498f3cbace0b2ed7f 267 Gene3D G3DSA:3.40.50.720 3 267 3.7E-66 T 14-10-2018 C2I25_08190 d8b898616e90fcfb0ce91b79f3158dbf 152 SUPERFAMILY SSF46785 3 143 1.09E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08190 d8b898616e90fcfb0ce91b79f3158dbf 152 Pfam PF01047 MarR family 35 93 2.0E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_08190 d8b898616e90fcfb0ce91b79f3158dbf 152 SMART SM00347 28 128 6.3E-28 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_08190 d8b898616e90fcfb0ce91b79f3158dbf 152 Gene3D G3DSA:1.10.10.10 5 146 3.9E-43 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_08190 d8b898616e90fcfb0ce91b79f3158dbf 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.8E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_08190 d8b898616e90fcfb0ce91b79f3158dbf 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.8E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_08190 d8b898616e90fcfb0ce91b79f3158dbf 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.8E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_18920 158c41884f069388d1aed4643d697bb2 307 Pfam PF12146 Serine aminopeptidase, S33 80 189 7.0E-10 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 C2I25_18920 158c41884f069388d1aed4643d697bb2 307 Gene3D G3DSA:3.40.50.1820 53 307 5.9E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_18920 158c41884f069388d1aed4643d697bb2 307 SUPERFAMILY SSF53474 20 305 1.39E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_27700 a18733a8bf05c9c8a257eeaa25249a56 527 Gene3D G3DSA:3.40.630.30 3 164 1.1E-16 T 14-10-2018 C2I25_27700 a18733a8bf05c9c8a257eeaa25249a56 527 Pfam PF00266 Aminotransferase class-V 200 473 1.6E-13 T 14-10-2018 IPR000192 Aminotransferase class V domain C2I25_27700 a18733a8bf05c9c8a257eeaa25249a56 527 Gene3D G3DSA:3.90.1150.10 184 518 6.9E-73 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_27700 a18733a8bf05c9c8a257eeaa25249a56 527 Gene3D G3DSA:3.40.640.10 192 424 6.9E-73 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_27700 a18733a8bf05c9c8a257eeaa25249a56 527 SUPERFAMILY SSF55729 5 164 3.48E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27700 a18733a8bf05c9c8a257eeaa25249a56 527 Pfam PF13444 Acetyltransferase (GNAT) domain 20 112 6.4E-10 T 14-10-2018 C2I25_27700 a18733a8bf05c9c8a257eeaa25249a56 527 SUPERFAMILY SSF53383 180 520 5.37E-57 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_07540 b5644c90ab6250b5ace18b53e16fc2cb 151 Gene3D G3DSA:3.40.30.10 47 147 6.0E-23 T 14-10-2018 C2I25_07540 b5644c90ab6250b5ace18b53e16fc2cb 151 Pfam PF00085 Thioredoxin 59 148 3.2E-16 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I25_07540 b5644c90ab6250b5ace18b53e16fc2cb 151 SUPERFAMILY SSF52833 52 149 3.05E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_20635 81c04c342a3ba675e6d0197d487c04f1 86 Gene3D G3DSA:3.30.110.20 1 86 7.2E-35 T 14-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 C2I25_20635 81c04c342a3ba675e6d0197d487c04f1 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 1.7E-38 T 14-10-2018 IPR007347 Sporulation stage V, protein S C2I25_20635 81c04c342a3ba675e6d0197d487c04f1 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 1.0E-40 T 14-10-2018 IPR007347 Sporulation stage V, protein S C2I25_13575 9ed5ecb7a2e81f4a0a647e88041f2d59 247 PIRSF PIRSF017388 2 247 2.7E-94 T 14-10-2018 IPR012354 Esterase/lipase GO:0052689 C2I25_13575 9ed5ecb7a2e81f4a0a647e88041f2d59 247 Gene3D G3DSA:3.40.50.1820 1 247 1.6E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_13575 9ed5ecb7a2e81f4a0a647e88041f2d59 247 SUPERFAMILY SSF53474 12 246 4.3E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_13575 9ed5ecb7a2e81f4a0a647e88041f2d59 247 Pfam PF12146 Serine aminopeptidase, S33 17 229 5.7E-17 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 C2I25_24420 ca0a656fd7cf87cd618a2b04d540fae1 142 Gene3D G3DSA:1.10.10.10 6 142 6.8E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24420 ca0a656fd7cf87cd618a2b04d540fae1 142 Pfam PF01047 MarR family 33 89 1.7E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24420 ca0a656fd7cf87cd618a2b04d540fae1 142 SMART SM00347 25 125 2.0E-26 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24420 ca0a656fd7cf87cd618a2b04d540fae1 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 3.2E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24420 ca0a656fd7cf87cd618a2b04d540fae1 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 3.2E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24420 ca0a656fd7cf87cd618a2b04d540fae1 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 3.2E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24420 ca0a656fd7cf87cd618a2b04d540fae1 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 3.2E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_24420 ca0a656fd7cf87cd618a2b04d540fae1 142 SUPERFAMILY SSF46785 21 140 1.66E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.6E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.6E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.6E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.6E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.6E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.6E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 Gene3D G3DSA:3.40.50.720 1 252 2.8E-85 T 14-10-2018 C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 249 1.3E-55 T 14-10-2018 C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_02430 836832f3a59896b1d7f2a73e97990dbc 252 SUPERFAMILY SSF51735 3 250 1.48E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_03385 7844855f49070cc517da74d23851b867 161 Pfam PF06177 QueT transporter 7 153 3.8E-31 T 14-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 C2I25_03385 7844855f49070cc517da74d23851b867 161 PIRSF PIRSF031501 1 161 1.2E-54 T 14-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 C2I25_25830 e2500fe8032c4a07c4a4c782bcd232d3 259 Gene3D G3DSA:1.10.10.2520 144 223 9.8E-32 T 14-10-2018 C2I25_25830 e2500fe8032c4a07c4a4c782bcd232d3 259 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 32 259 1.3E-101 T 14-10-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 C2I25_25830 e2500fe8032c4a07c4a4c782bcd232d3 259 SUPERFAMILY SSF47090 34 100 2.62E-20 T 14-10-2018 IPR036365 PGBD-like superfamily C2I25_25830 e2500fe8032c4a07c4a4c782bcd232d3 259 Gene3D G3DSA:1.10.101.10 28 111 9.7E-22 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I25_25830 e2500fe8032c4a07c4a4c782bcd232d3 259 Pfam PF07486 Cell Wall Hydrolase 160 258 1.6E-28 T 14-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I25_25830 e2500fe8032c4a07c4a4c782bcd232d3 259 Gene3D G3DSA:2.40.10.420 224 259 3.6E-23 T 14-10-2018 C2I25_25830 e2500fe8032c4a07c4a4c782bcd232d3 259 Pfam PF01471 Putative peptidoglycan binding domain 43 99 2.0E-17 T 14-10-2018 IPR002477 Peptidoglycan binding-like C2I25_24835 7bc7ef1b8d8df448dc5705a23039ef22 1038 Gene3D G3DSA:1.20.1640.10 143 339 2.9E-8 T 14-10-2018 C2I25_24835 7bc7ef1b8d8df448dc5705a23039ef22 1038 SUPERFAMILY SSF82866 828 1026 1.03E-23 T 14-10-2018 C2I25_24835 7bc7ef1b8d8df448dc5705a23039ef22 1038 Pfam PF03176 MMPL family 719 1028 5.2E-42 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I25_24835 7bc7ef1b8d8df448dc5705a23039ef22 1038 Pfam PF03176 MMPL family 43 366 3.2E-60 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I25_24835 7bc7ef1b8d8df448dc5705a23039ef22 1038 SUPERFAMILY SSF82866 146 337 5.75E-30 T 14-10-2018 C2I25_24835 7bc7ef1b8d8df448dc5705a23039ef22 1038 SUPERFAMILY SSF58104 500 750 4.45E-7 T 14-10-2018 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.2E-5 T 14-10-2018 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 1.2E-5 T 14-10-2018 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 SUPERFAMILY SSF51905 7 261 2.4E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 Gene3D G3DSA:3.50.50.60 2 224 3.3E-83 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 Gene3D G3DSA:3.50.50.60 296 458 1.0E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 Pfam PF01134 Glucose inhibited division protein A 9 398 1.8E-172 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.588 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 Gene3D G3DSA:1.10.10.1800 459 549 2.5E-26 T 14-10-2018 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 Pfam PF13932 GidA associated domain 401 615 3.3E-79 T 14-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 Gene3D G3DSA:1.10.150.570 568 620 1.2E-23 T 14-10-2018 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 4.7E-295 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 C2I25_11675 b7222066a32c834877725f6ba24b0de9 629 SMART SM01228 545 616 6.0E-43 T 14-10-2018 C2I25_13165 26549611278b12ddd95e513b049e0ac4 105 Gene3D G3DSA:1.20.58.280 1 104 9.5E-42 T 14-10-2018 C2I25_13165 26549611278b12ddd95e513b049e0ac4 105 PIRSF PIRSF000699 1 105 2.7E-40 T 14-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I25_13165 26549611278b12ddd95e513b049e0ac4 105 SUPERFAMILY SSF46973 2 100 2.22E-38 T 14-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 C2I25_13165 26549611278b12ddd95e513b049e0ac4 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 99 1.3E-39 T 14-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I25_02985 86a8c1eb40826481ff6ced9591569e4b 278 Gene3D G3DSA:1.10.10.10 1 101 3.6E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02985 86a8c1eb40826481ff6ced9591569e4b 278 SUPERFAMILY SSF46785 2 97 3.19E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02985 86a8c1eb40826481ff6ced9591569e4b 278 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 74 5.5E-24 T 14-10-2018 IPR002831 Transcription regulator TrmB, N-terminal C2I25_02985 86a8c1eb40826481ff6ced9591569e4b 278 Pfam PF11495 Archaeal transcriptional regulator TrmB 108 227 1.5E-7 T 14-10-2018 IPR021586 Transcription regulator TrmB, C-terminal C2I25_17020 91db80e8afb7017b7b00109a45f771f7 283 Gene3D G3DSA:2.40.10.350 186 261 4.2E-30 T 14-10-2018 C2I25_17020 91db80e8afb7017b7b00109a45f771f7 283 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 7 277 1.3E-59 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I25_17020 91db80e8afb7017b7b00109a45f771f7 283 Pfam PF04085 rod shape-determining protein MreC 123 273 5.5E-43 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I25_17020 91db80e8afb7017b7b00109a45f771f7 283 PIRSF PIRSF038471 2 283 1.8E-64 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I25_17020 91db80e8afb7017b7b00109a45f771f7 283 Gene3D G3DSA:2.40.10.340 113 185 1.9E-24 T 14-10-2018 C2I25_08795 e1e1ccc6d87c5efcb48587298206ff7f 153 Pfam PF00293 NUDIX domain 8 112 9.9E-21 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_08795 e1e1ccc6d87c5efcb48587298206ff7f 153 PRINTS PR00502 NUDIX hydrolase family signature 49 64 1.7E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_08795 e1e1ccc6d87c5efcb48587298206ff7f 153 PRINTS PR00502 NUDIX hydrolase family signature 35 49 1.7E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_08795 e1e1ccc6d87c5efcb48587298206ff7f 153 SUPERFAMILY SSF55811 4 140 1.02E-28 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_08795 e1e1ccc6d87c5efcb48587298206ff7f 153 Gene3D G3DSA:3.90.79.10 3 137 6.4E-30 T 14-10-2018 C2I25_08795 e1e1ccc6d87c5efcb48587298206ff7f 153 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_15145 158d411d0358f72795ae38649bc0c138 75 Pfam PF04023 FeoA domain 1 73 3.2E-15 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 C2I25_15145 158d411d0358f72795ae38649bc0c138 75 SUPERFAMILY SSF50037 3 73 5.8E-15 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal C2I25_15145 158d411d0358f72795ae38649bc0c138 75 SMART SM00899 1 74 7.3E-18 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 C2I25_15145 158d411d0358f72795ae38649bc0c138 75 Gene3D G3DSA:2.30.30.90 1 75 2.0E-17 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain C2I25_15980 fcfac68dc6e8c992fb0792a1a0126cbe 181 Pfam PF08281 Sigma-70, region 4 115 167 1.4E-17 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_15980 fcfac68dc6e8c992fb0792a1a0126cbe 181 Gene3D G3DSA:1.10.10.10 110 178 5.9E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15980 fcfac68dc6e8c992fb0792a1a0126cbe 181 SUPERFAMILY SSF88659 108 172 2.62E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_15980 fcfac68dc6e8c992fb0792a1a0126cbe 181 SUPERFAMILY SSF88946 7 109 7.06E-20 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_15980 fcfac68dc6e8c992fb0792a1a0126cbe 181 Gene3D G3DSA:1.10.1740.10 7 89 2.4E-16 T 14-10-2018 C2I25_15980 fcfac68dc6e8c992fb0792a1a0126cbe 181 Pfam PF04542 Sigma-70 region 2 30 92 4.0E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_15980 fcfac68dc6e8c992fb0792a1a0126cbe 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 171 2.1E-25 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_19930 8992a61a6fbeb257df32748549bf5ea4 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19930 8992a61a6fbeb257df32748549bf5ea4 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 24.131 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19930 8992a61a6fbeb257df32748549bf5ea4 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 59 4.3E-5 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19930 8992a61a6fbeb257df32748549bf5ea4 324 Pfam PF00953 Glycosyl transferase family 4 83 248 1.0E-37 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 C2I25_19930 8992a61a6fbeb257df32748549bf5ea4 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 320 9.1E-120 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_13485 7a5b97843eb767a08f4ead31eddb399b 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 110 8.4E-40 T 14-10-2018 IPR005562 SpoVA C2I25_13485 7a5b97843eb767a08f4ead31eddb399b 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 6.5E-51 T 14-10-2018 IPR014204 Sporulation stage V, protein AE C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 Gene3D G3DSA:3.30.360.10 130 326 9.9E-145 T 14-10-2018 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 344 3.2E-160 T 14-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 122 1.5E-34 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 343 38.655 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 SMART SM00859 8 123 2.1E-44 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 329 3.9E-58 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 SUPERFAMILY SSF55347 131 330 6.25E-75 T 14-10-2018 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 14-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 PIRSF PIRSF000148 6 348 3.4E-130 T 14-10-2018 C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 SUPERFAMILY SSF51735 7 158 2.38E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_20510 148777ecbcb272639b2153dbc80e69ab 348 Gene3D G3DSA:3.40.50.720 9 340 9.9E-145 T 14-10-2018 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 2 83 3.1E-15 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 5 562 1.6E-155 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 Pfam PF00750 tRNA synthetases class I (R) 94 435 1.5E-99 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 SUPERFAMILY SSF55190 7 105 3.01E-23 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 SMART SM00836 450 562 1.6E-40 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 Gene3D G3DSA:1.10.730.10 444 562 3.7E-35 T 14-10-2018 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 5.4E-20 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 5.4E-20 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 5.4E-20 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 5.4E-20 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 Hamap MF_00123 Arginine--tRNA ligase [argS]. 1 562 25.616 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 SUPERFAMILY SSF52374 112 444 5.0E-97 T 14-10-2018 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 Pfam PF05746 DALR anticodon binding domain 450 562 7.8E-32 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 Gene3D G3DSA:3.30.1360.70 2 105 3.0E-28 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 SUPERFAMILY SSF47323 444 562 3.4E-33 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 SMART SM01016 1 84 5.5E-19 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_00500 f269ca3b5c854dc09a703dbcd51299e8 562 Gene3D G3DSA:3.40.50.620 108 443 8.8E-124 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_12335 b82209e303bddee281f739ffca279188 120 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 2 116 5.6E-10 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_12335 b82209e303bddee281f739ffca279188 120 Gene3D G3DSA:2.40.50.480 33 118 2.5E-17 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_12335 b82209e303bddee281f739ffca279188 120 Pfam PF06486 Protein of unknown function (DUF1093) 43 107 2.8E-10 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_12335 b82209e303bddee281f739ffca279188 120 SUPERFAMILY SSF159121 39 118 4.71E-19 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Gene3D G3DSA:3.30.70.250 1 84 5.5E-38 T 14-10-2018 C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 SUPERFAMILY SSF51161 88 226 1.26E-51 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 46.565 T 14-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 5.5E-10 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 119 2.5E-5 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 9.5E-118 T 14-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 200 3.0E-9 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Gene3D G3DSA:2.160.10.10 85 236 4.3E-52 T 14-10-2018 C2I25_19580 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 3.6E-36 T 14-10-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 C2I25_05620 438f2396b1cde454081402d82796bb96 413 Gene3D G3DSA:3.20.20.80 9 124 3.6E-40 T 14-10-2018 C2I25_05620 438f2396b1cde454081402d82796bb96 413 Gene3D G3DSA:3.20.20.80 125 296 2.5E-28 T 14-10-2018 C2I25_05620 438f2396b1cde454081402d82796bb96 413 Pfam PF00128 Alpha amylase, catalytic domain 163 265 8.0E-7 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_05620 438f2396b1cde454081402d82796bb96 413 Pfam PF00128 Alpha amylase, catalytic domain 50 118 8.4E-24 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_05620 438f2396b1cde454081402d82796bb96 413 SUPERFAMILY SSF51011 301 382 3.34E-11 T 14-10-2018 C2I25_05620 438f2396b1cde454081402d82796bb96 413 Gene3D G3DSA:2.60.40.1180 297 391 8.3E-34 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_05620 438f2396b1cde454081402d82796bb96 413 SMART SM00642 22 292 8.0E-10 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_05620 438f2396b1cde454081402d82796bb96 413 SUPERFAMILY SSF51445 12 301 1.41E-49 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_21610 510854c9ae5ed51ee67e18ede131462f 177 Pfam PF04542 Sigma-70 region 2 35 95 6.8E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_21610 510854c9ae5ed51ee67e18ede131462f 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 174 1.4E-24 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_21610 510854c9ae5ed51ee67e18ede131462f 177 SUPERFAMILY SSF88946 14 111 1.29E-19 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_21610 510854c9ae5ed51ee67e18ede131462f 177 Pfam PF08281 Sigma-70, region 4 122 170 2.9E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_21610 510854c9ae5ed51ee67e18ede131462f 177 Gene3D G3DSA:1.10.10.10 112 176 9.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_21610 510854c9ae5ed51ee67e18ede131462f 177 Gene3D G3DSA:1.10.1740.10 10 110 3.1E-20 T 14-10-2018 C2I25_21610 510854c9ae5ed51ee67e18ede131462f 177 SUPERFAMILY SSF88659 114 174 5.05E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_09675 18459d1d73a406e10cdab81411508573 235 Pfam PF01863 Protein of unknown function DUF45 20 227 1.4E-60 T 14-10-2018 IPR002725 Protein of unknown function DUF45 C2I25_09675 18459d1d73a406e10cdab81411508573 235 Gene3D G3DSA:3.30.2010.10 135 230 3.9E-17 T 14-10-2018 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Gene3D G3DSA:1.10.8.500 195 245 4.9E-11 T 14-10-2018 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SUPERFAMILY SSF55785 243 356 7.44E-8 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SMART SM00387 477 590 4.8E-41 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Gene3D G3DSA:3.30.565.10 438 589 1.3E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Gene3D G3DSA:1.10.287.130 356 436 1.0E-25 T 14-10-2018 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 588 1.3E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SUPERFAMILY SSF47384 348 432 4.51E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 2.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 2.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 568 2.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 574 587 2.2E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SUPERFAMILY SSF55874 420 587 2.1E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SMART SM00091 255 324 1.8E-4 T 14-10-2018 IPR000014 PAS domain C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 431 1.3E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Gene3D G3DSA:3.30.450.20 246 355 8.6E-18 T 14-10-2018 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SUPERFAMILY SSF158472 197 244 4.58E-9 T 14-10-2018 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Pfam PF00672 HAMP domain 197 243 6.7E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SMART SM00304 196 248 1.2E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_04015 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SMART SM00388 364 431 5.4E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_15645 7f2715a918d47d94c645106e4507e408 171 Gene3D G3DSA:3.40.50.300 3 171 9.3E-52 T 14-10-2018 C2I25_15645 7f2715a918d47d94c645106e4507e408 171 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 7 138 4.5E-31 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 C2I25_15645 7f2715a918d47d94c645106e4507e408 171 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 7 137 3.2E-34 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 C2I25_15645 7f2715a918d47d94c645106e4507e408 171 SUPERFAMILY SSF52540 6 137 8.91E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10695 8a4c503c69cb0d3f0d13d5ab360e3afd 381 Pfam PF02595 Glycerate kinase family 3 374 2.3E-148 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 C2I25_10695 8a4c503c69cb0d3f0d13d5ab360e3afd 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 3.0E-157 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 C2I25_10695 8a4c503c69cb0d3f0d13d5ab360e3afd 381 SUPERFAMILY SSF110738 2 375 7.85E-139 T 14-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 C2I25_10695 8a4c503c69cb0d3f0d13d5ab360e3afd 381 PIRSF PIRSF006078 1 378 2.9E-140 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 C2I25_10695 8a4c503c69cb0d3f0d13d5ab360e3afd 381 Gene3D G3DSA:3.40.50.10350 2 362 9.1E-140 T 14-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold C2I25_10695 8a4c503c69cb0d3f0d13d5ab360e3afd 381 Gene3D G3DSA:3.90.1510.10 42 276 9.1E-140 T 14-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 C2I25_25950 a394bf711167b425cfece8d11651b361 476 Pfam PF02687 FtsX-like permease family 342 468 9.7E-13 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_24890 4b53727092093b42ab98f6137f7ee276 233 Gene3D G3DSA:3.30.460.10 5 113 2.3E-10 T 14-10-2018 C2I25_24890 4b53727092093b42ab98f6137f7ee276 233 SUPERFAMILY SSF81301 4 109 2.94E-11 T 14-10-2018 C2I25_24890 4b53727092093b42ab98f6137f7ee276 233 Pfam PF01909 Nucleotidyltransferase domain 23 43 2.4E-5 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 Gene3D G3DSA:2.40.340.10 337 406 3.7E-115 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 SUPERFAMILY SSF63882 8 184 6.02E-50 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 Pfam PF03454 MoeA C-terminal region (domain IV) 341 411 1.8E-17 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 176 9.8E-39 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 Gene3D G3DSA:2.170.190.11 50 150 3.7E-115 T 14-10-2018 C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 2.3E-33 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 Gene3D G3DSA:3.40.980.10 184 336 3.7E-115 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 SUPERFAMILY SSF63867 338 412 2.62E-16 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 SUPERFAMILY SSF53218 186 329 2.75E-40 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 Pfam PF00994 Probable molybdopterin binding domain 189 326 9.4E-26 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 SMART SM00852 189 327 6.7E-39 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_15640 24e1bf111b93ed133f6c28d8406243aa 429 Gene3D G3DSA:3.90.105.10 26 183 3.7E-115 T 14-10-2018 C2I25_11885 c168cb9036a6ab4db4f17a9876bfb86e 867 SUPERFAMILY SSF158745 510 842 4.58E-27 T 14-10-2018 C2I25_11885 c168cb9036a6ab4db4f17a9876bfb86e 867 SMART SM01260 515 838 9.0E-5 T 14-10-2018 IPR007822 Lanthionine synthetase C-like C2I25_11885 c168cb9036a6ab4db4f17a9876bfb86e 867 Gene3D G3DSA:1.10.510.10 310 419 1.5E-18 T 14-10-2018 C2I25_11885 c168cb9036a6ab4db4f17a9876bfb86e 867 SMART SM00220 223 477 0.0019 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_11885 c168cb9036a6ab4db4f17a9876bfb86e 867 SUPERFAMILY SSF56112 221 422 1.26E-24 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_11885 c168cb9036a6ab4db4f17a9876bfb86e 867 Pfam PF00069 Protein kinase domain 234 411 3.2E-16 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_11885 c168cb9036a6ab4db4f17a9876bfb86e 867 Gene3D G3DSA:3.30.200.20 221 309 1.5E-18 T 14-10-2018 C2I25_08455 52985610d86a2e856ea861f699458671 392 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 391 5.9E-58 T 14-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I25_08455 52985610d86a2e856ea861f699458671 392 Pfam PF07670 Nucleoside recognition 91 188 1.0E-5 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I25_08455 52985610d86a2e856ea861f699458671 392 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.2E-20 T 14-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I25_26300 96f56f0e20194a2ab2c6b1333ecd5cd4 341 Gene3D G3DSA:3.40.710.10 7 341 3.2E-110 T 14-10-2018 C2I25_26300 96f56f0e20194a2ab2c6b1333ecd5cd4 341 Pfam PF00144 Beta-lactamase 9 331 3.9E-43 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_26300 96f56f0e20194a2ab2c6b1333ecd5cd4 341 SUPERFAMILY SSF56601 5 330 3.7E-75 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_01860 26b6a228a6e32f21e5bbe37fcc4e2265 317 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 61 296 3.1E-65 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_01860 26b6a228a6e32f21e5bbe37fcc4e2265 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 91 102 8.5E-14 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_01860 26b6a228a6e32f21e5bbe37fcc4e2265 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 171 184 8.5E-14 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_01860 26b6a228a6e32f21e5bbe37fcc4e2265 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 161 8.5E-14 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_01860 26b6a228a6e32f21e5bbe37fcc4e2265 317 Gene3D G3DSA:3.40.710.10 41 314 8.6E-84 T 14-10-2018 C2I25_01860 26b6a228a6e32f21e5bbe37fcc4e2265 317 SUPERFAMILY SSF56601 9 313 2.89E-68 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 PIRSF PIRSF000097 2 117 3.7E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 PIRSF PIRSF000097 113 273 8.7E-55 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 SUPERFAMILY SSF51430 5 266 1.1E-96 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 Gene3D G3DSA:3.20.20.100 1 274 1.5E-123 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 228 243 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 Pfam PF00248 Aldo/keto reductase family 24 259 8.1E-50 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 PRINTS PR00069 Aldo-keto reductase signature 157 186 4.3E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.3E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 PRINTS PR00069 Aldo-keto reductase signature 93 111 4.3E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 PRINTS PR00069 Aldo-keto reductase signature 123 140 4.3E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_18965 d0790284ebaaadd7b94e99e44d209603 275 PRINTS PR00069 Aldo-keto reductase signature 195 219 4.3E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_26155 1bb1629f780cc29f509b7d44f6fcb891 208 Pfam PF03596 Cadmium resistance transporter 42 205 3.5E-29 T 14-10-2018 IPR004676 Cadmium resistance transporter C2I25_15430 06ef4b51b4576aba4563c546d1794dab 169 Gene3D G3DSA:3.40.980.10 1 168 9.2E-54 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_15430 06ef4b51b4576aba4563c546d1794dab 169 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 157 3.0E-39 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_15430 06ef4b51b4576aba4563c546d1794dab 169 Pfam PF00994 Probable molybdopterin binding domain 18 161 1.3E-38 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_15430 06ef4b51b4576aba4563c546d1794dab 169 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 C2I25_15430 06ef4b51b4576aba4563c546d1794dab 169 SMART SM00852 17 162 1.9E-34 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_15430 06ef4b51b4576aba4563c546d1794dab 169 PIRSF PIRSF006443 1 169 1.9E-69 T 14-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 C2I25_15430 06ef4b51b4576aba4563c546d1794dab 169 SUPERFAMILY SSF53218 8 163 4.58E-45 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_13105 3ca1ea1bbe272afb42b4cf4c66ca3e6b 586 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 128 554 99.345 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I25_13105 3ca1ea1bbe272afb42b4cf4c66ca3e6b 586 Pfam PF01964 Radical SAM ThiC family 129 549 7.4E-205 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I25_13105 3ca1ea1bbe272afb42b4cf4c66ca3e6b 586 Pfam PF13667 ThiC-associated domain 16 88 6.8E-28 T 14-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I25_13105 3ca1ea1bbe272afb42b4cf4c66ca3e6b 586 Gene3D G3DSA:3.20.20.540 172 485 3.9E-156 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I25_13105 3ca1ea1bbe272afb42b4cf4c66ca3e6b 586 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 128 552 2.7E-222 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I25_14550 ece365489351b970ed097dc4531b659c 295 Gene3D G3DSA:3.90.550.10 1 292 1.5E-95 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_14550 ece365489351b970ed097dc4531b659c 295 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 1.7E-122 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 C2I25_14550 ece365489351b970ed097dc4531b659c 295 Pfam PF00483 Nucleotidyl transferase 6 258 1.7E-35 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_14550 ece365489351b970ed097dc4531b659c 295 SUPERFAMILY SSF53448 4 275 3.76E-70 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_00790 fd5113381cc82a2f724495abff25899d 310 SUPERFAMILY SSF101908 33 301 2.75E-23 T 14-10-2018 C2I25_00790 fd5113381cc82a2f724495abff25899d 310 Gene3D G3DSA:2.130.10.10 207 302 1.2E-6 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_00790 fd5113381cc82a2f724495abff25899d 310 Gene3D G3DSA:2.130.10.10 28 201 5.7E-9 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_20495 19ef9ec0b5564b20ffcefdd1d91d0577 83 Pfam PF05239 PRC-barrel domain 1 77 4.3E-13 T 14-10-2018 IPR027275 PRC-barrel domain C2I25_20495 19ef9ec0b5564b20ffcefdd1d91d0577 83 Gene3D G3DSA:2.30.30.240 1 76 6.2E-8 T 14-10-2018 C2I25_20495 19ef9ec0b5564b20ffcefdd1d91d0577 83 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 75 1.9E-28 T 14-10-2018 IPR014238 Sporulation protein YlmC/YmxH C2I25_20495 19ef9ec0b5564b20ffcefdd1d91d0577 83 SUPERFAMILY SSF50346 1 77 1.1E-11 T 14-10-2018 IPR011033 PRC-barrel-like superfamily C2I25_13115 075691304bf42073ac86e6a149f84157 341 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 331 6.7E-37 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I25_21630 ecf6a936feae70325b652940c66ffd1a 568 SUPERFAMILY SSF53850 52 561 2.53E-124 T 14-10-2018 C2I25_21630 ecf6a936feae70325b652940c66ffd1a 568 Gene3D G3DSA:3.40.190.10 68 552 7.2E-182 T 14-10-2018 C2I25_21630 ecf6a936feae70325b652940c66ffd1a 568 PIRSF PIRSF002741 2 568 3.1E-108 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_21630 ecf6a936feae70325b652940c66ffd1a 568 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 484 7.7E-79 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_21630 ecf6a936feae70325b652940c66ffd1a 568 Gene3D G3DSA:3.10.105.10 310 537 7.2E-182 T 14-10-2018 C2I25_21630 ecf6a936feae70325b652940c66ffd1a 568 Gene3D G3DSA:3.90.76.10 87 209 7.2E-182 T 14-10-2018 C2I25_03245 66f7debd86b3362c19ac051910c03ff7 72 Gene3D G3DSA:1.20.58.990 19 72 2.6E-27 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_03245 66f7debd86b3362c19ac051910c03ff7 72 Pfam PF09388 Spo0E like sporulation regulatory protein 24 65 1.6E-12 T 14-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I25_03245 66f7debd86b3362c19ac051910c03ff7 72 SUPERFAMILY SSF140500 19 70 1.05E-14 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_25805 5606d482ff9ce64a27ca0736367bb287 209 Pfam PF04199 Putative cyclase 7 152 4.4E-22 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I25_25805 5606d482ff9ce64a27ca0736367bb287 209 Gene3D G3DSA:3.50.30.50 1 209 2.4E-83 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I25_25805 5606d482ff9ce64a27ca0736367bb287 209 TIGRFAM TIGR03035 trp_arylform: arylformamidase 6 209 5.1E-100 T 14-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I25_25805 5606d482ff9ce64a27ca0736367bb287 209 SUPERFAMILY SSF102198 4 206 2.62E-61 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I25_25805 5606d482ff9ce64a27ca0736367bb287 209 Hamap MF_01969 Kynurenine formamidase [kynB]. 5 209 43.502 T 14-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I25_09460 ce5391b8c6d0142877f4f37dfdad34ef 444 SUPERFAMILY SSF56176 6 204 3.22E-49 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_09460 ce5391b8c6d0142877f4f37dfdad34ef 444 Gene3D G3DSA:3.30.43.10 8 86 6.7E-21 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 C2I25_09460 ce5391b8c6d0142877f4f37dfdad34ef 444 Gene3D G3DSA:3.30.465.50 90 441 2.5E-100 T 14-10-2018 C2I25_09460 ce5391b8c6d0142877f4f37dfdad34ef 444 Pfam PF08031 Berberine and berberine like 397 440 6.4E-21 T 14-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 C2I25_09460 ce5391b8c6d0142877f4f37dfdad34ef 444 Pfam PF01565 FAD binding domain 35 163 2.3E-26 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I25_09460 ce5391b8c6d0142877f4f37dfdad34ef 444 Gene3D G3DSA:3.40.462.20 206 395 2.5E-100 T 14-10-2018 C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 3.2E-5 T 14-10-2018 C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 3.2E-5 T 14-10-2018 C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 3.2E-5 T 14-10-2018 C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 3.2E-5 T 14-10-2018 C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 Gene3D G3DSA:1.20.1250.20 256 462 1.0E-22 T 14-10-2018 C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 Gene3D G3DSA:1.20.1720.10 12 244 2.1E-50 T 14-10-2018 C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 Pfam PF07690 Major Facilitator Superfamily 17 406 1.0E-50 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 SUPERFAMILY SSF103473 11 451 2.88E-70 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_28140 f1b837f90e987fa93cd31ed3b3e06c65 476 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 10 415 1.6E-98 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_27725 63367c15e440b7a3bba828d48a5b635c 427 Pfam PF02378 Phosphotransferase system, EIIC 29 344 3.5E-57 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_27725 63367c15e440b7a3bba828d48a5b635c 427 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 17 418 2.7E-120 T 14-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 C2I25_27725 63367c15e440b7a3bba828d48a5b635c 427 PIRSF PIRSF006351 1 425 1.1E-148 T 14-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 256 1.6E-64 T 14-10-2018 C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 SUPERFAMILY SSF51735 4 257 5.53E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 Gene3D G3DSA:3.40.50.720 1 258 3.8E-80 T 14-10-2018 C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 258 6.4E-111 T 14-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19320 ff23a7fc64381f9674442f7810a43b16 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.8E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16680 dd768466c6256de8a12b4a6c6405c168 678 SUPERFAMILY SSF81345 5 329 1.15E-71 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_16680 dd768466c6256de8a12b4a6c6405c168 678 Gene3D G3DSA:1.10.3470.10 8 336 2.0E-87 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_16680 dd768466c6256de8a12b4a6c6405c168 678 Pfam PF01032 FecCD transport family 20 329 7.5E-88 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_16680 dd768466c6256de8a12b4a6c6405c168 678 Pfam PF01032 FecCD transport family 364 672 1.3E-87 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_16680 dd768466c6256de8a12b4a6c6405c168 678 SUPERFAMILY SSF81345 351 672 4.71E-79 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_16680 dd768466c6256de8a12b4a6c6405c168 678 Gene3D G3DSA:1.10.3470.10 353 678 7.4E-91 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 SUPERFAMILY SSF53092 1 136 9.42E-37 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 138 9.7E-29 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 4.1E-9 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 4.1E-9 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 209 4.1E-9 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 Pfam PF00557 Metallopeptidase family M24 147 348 1.8E-65 T 14-10-2018 IPR000994 Peptidase M24 C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 SUPERFAMILY SSF55920 137 363 7.85E-82 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 Gene3D G3DSA:3.90.230.10 137 362 3.2E-84 T 14-10-2018 C2I25_16230 cedf2ecb04548c32d4b8ed915b68859e 365 Gene3D G3DSA:3.40.350.10 2 136 5.0E-42 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I25_09070 08e05f708143e237d403364520a9a8d7 414 PIRSF PIRSF500136 1 414 2.4E-150 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 Gene3D G3DSA:3.40.50.720 205 414 2.9E-53 T 14-10-2018 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 406 1.9E-134 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 187 1.8E-39 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 SMART SM00984 317 411 3.5E-28 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 SUPERFAMILY SSF52413 314 410 1.96E-18 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 PIRSF PIRSF000124 5 413 2.1E-65 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 SUPERFAMILY SSF51735 6 196 5.34E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_09070 08e05f708143e237d403364520a9a8d7 414 Gene3D G3DSA:3.40.50.720 1 200 1.1E-57 T 14-10-2018 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 SUPERFAMILY SSF48179 205 298 1.33E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 410 1.3E-19 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I25_09070 08e05f708143e237d403364520a9a8d7 414 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 296 1.7E-26 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I25_04350 6c5c3ff4f35c7420b415471156334b99 101 SUPERFAMILY SSF141734 7 99 1.31E-44 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 C2I25_04350 6c5c3ff4f35c7420b415471156334b99 101 Gene3D G3DSA:3.10.20.400 1 88 2.0E-39 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 C2I25_04350 6c5c3ff4f35c7420b415471156334b99 101 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 47 101 2.0E-26 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 C2I25_04350 6c5c3ff4f35c7420b415471156334b99 101 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 24 97 2.7E-35 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 C2I25_04350 6c5c3ff4f35c7420b415471156334b99 101 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 101 28.514 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 C2I25_27280 888e4f7baa354c4c13096590346cffac 466 SUPERFAMILY SSF58100 32 367 1.49E-94 T 14-10-2018 C2I25_27280 888e4f7baa354c4c13096590346cffac 466 Gene3D G3DSA:1.20.1170.10 39 372 2.7E-108 T 14-10-2018 C2I25_27280 888e4f7baa354c4c13096590346cffac 466 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 46 223 5.6E-58 T 14-10-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 C2I25_05000 eb5cfe1f1ee3d8d7def9bf536f050a35 796 SUPERFAMILY SSF55486 281 430 4.81E-17 T 14-10-2018 C2I25_05000 eb5cfe1f1ee3d8d7def9bf536f050a35 796 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 183 493 5.6E-86 T 14-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I25_05000 eb5cfe1f1ee3d8d7def9bf536f050a35 796 PIRSF PIRSF007519 1 796 0.0 T 14-10-2018 IPR012300 Peptidase M6, InhA C2I25_05000 eb5cfe1f1ee3d8d7def9bf536f050a35 796 Pfam PF05547 Immune inhibitor A peptidase M6 150 792 0.0 T 14-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I25_13375 3b201ff8d9716d16e412d42a57507a1b 254 SMART SM00422 5 74 1.1E-27 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13375 3b201ff8d9716d16e412d42a57507a1b 254 Gene3D G3DSA:1.10.1660.10 3 136 1.6E-33 T 14-10-2018 C2I25_13375 3b201ff8d9716d16e412d42a57507a1b 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 6.8E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13375 3b201ff8d9716d16e412d42a57507a1b 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 6.8E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13375 3b201ff8d9716d16e412d42a57507a1b 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 6.8E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13375 3b201ff8d9716d16e412d42a57507a1b 254 SUPERFAMILY SSF46955 6 117 1.43E-27 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_13375 3b201ff8d9716d16e412d42a57507a1b 254 Pfam PF13411 MerR HTH family regulatory protein 6 71 8.7E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_17280 1b13cc858d0c06619c935bea17566479 428 SMART SM00382 38 150 1.9E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_17280 1b13cc858d0c06619c935bea17566479 428 Gene3D G3DSA:1.10.3710.10 332 427 1.7E-25 T 14-10-2018 C2I25_17280 1b13cc858d0c06619c935bea17566479 428 Gene3D G3DSA:1.20.272.10 228 331 1.0E-40 T 14-10-2018 C2I25_17280 1b13cc858d0c06619c935bea17566479 428 SUPERFAMILY SSF52540 3 228 2.85E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17280 1b13cc858d0c06619c935bea17566479 428 Gene3D G3DSA:1.10.8.60 150 225 4.4E-17 T 14-10-2018 C2I25_17280 1b13cc858d0c06619c935bea17566479 428 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 418 5.5E-66 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal C2I25_17280 1b13cc858d0c06619c935bea17566479 428 SUPERFAMILY SSF48019 238 419 2.89E-70 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 C2I25_17280 1b13cc858d0c06619c935bea17566479 428 Gene3D G3DSA:3.40.50.300 1 149 2.6E-40 T 14-10-2018 C2I25_17280 1b13cc858d0c06619c935bea17566479 428 Pfam PF16193 AAA C-terminal domain 172 252 1.3E-24 T 14-10-2018 IPR032423 AAA C-terminal domain C2I25_17280 1b13cc858d0c06619c935bea17566479 428 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 144 6.2E-15 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 Gene3D G3DSA:1.20.1720.10 35 270 4.0E-38 T 14-10-2018 C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 34 466 2.1E-121 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 Pfam PF07690 Major Facilitator Superfamily 39 432 4.0E-53 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 SUPERFAMILY SSF103473 27 500 2.09E-67 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 Gene3D G3DSA:1.20.1250.20 283 508 3.1E-23 T 14-10-2018 C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 150 8.3E-11 T 14-10-2018 C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 38 62 8.3E-11 T 14-10-2018 C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 160 184 8.3E-11 T 14-10-2018 C2I25_23620 f69806fbbda4aa4809d92c32dcad6e9f 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 325 349 8.3E-11 T 14-10-2018 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 SUPERFAMILY SSF53901 4 269 1.52E-84 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 Gene3D G3DSA:3.40.47.10 5 276 1.1E-148 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 Pfam PF00108 Thiolase, N-terminal domain 5 263 5.7E-99 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 SUPERFAMILY SSF53901 271 392 5.26E-39 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 PIRSF PIRSF000429 1 393 1.8E-124 T 14-10-2018 IPR002155 Thiolase GO:0016747 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 4.4E-45 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 2.6E-141 T 14-10-2018 IPR002155 Thiolase GO:0016747 C2I25_12445 7194e4737283a6e3acfae9c7bc3b0fd0 393 Gene3D G3DSA:3.40.47.10 126 390 1.1E-148 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_28455 a8956be4a1493621af981068c87ac819 299 SUPERFAMILY SSF55729 129 279 1.45E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_28455 a8956be4a1493621af981068c87ac819 299 Gene3D G3DSA:3.40.630.30 121 276 5.2E-16 T 14-10-2018 C2I25_28455 a8956be4a1493621af981068c87ac819 299 Pfam PF13527 Acetyltransferase (GNAT) domain 130 241 4.7E-10 T 14-10-2018 C2I25_28455 a8956be4a1493621af981068c87ac819 299 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 18 279 3.9E-103 T 14-10-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 C2I25_05480 096db44fb4bfa3456e2706ff82a81a32 347 SMART SM00382 33 241 1.3E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_05480 096db44fb4bfa3456e2706ff82a81a32 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 297 6.9E-15 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_05480 096db44fb4bfa3456e2706ff82a81a32 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 2.6E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_05480 096db44fb4bfa3456e2706ff82a81a32 347 Pfam PF00005 ABC transporter 25 183 5.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_05480 096db44fb4bfa3456e2706ff82a81a32 347 SUPERFAMILY SSF52540 4 254 3.55E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05480 096db44fb4bfa3456e2706ff82a81a32 347 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_05480 096db44fb4bfa3456e2706ff82a81a32 347 Gene3D G3DSA:3.40.50.300 1 330 2.8E-103 T 14-10-2018 C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 Pfam PF00106 short chain dehydrogenase 3 201 1.0E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 Gene3D G3DSA:3.40.50.720 1 248 4.2E-53 T 14-10-2018 C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 SUPERFAMILY SSF51735 2 248 2.09E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_21845 8784943c0a5d5f0136035aa561a2aa96 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_25445 509373afab4cc4c5134338e3467dcfff 167 SUPERFAMILY SSF55729 13 165 1.01E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25445 509373afab4cc4c5134338e3467dcfff 167 Pfam PF00583 Acetyltransferase (GNAT) family 46 139 6.4E-14 T 14-10-2018 IPR000182 GNAT domain C2I25_25445 509373afab4cc4c5134338e3467dcfff 167 Gene3D G3DSA:3.40.630.30 5 167 1.2E-44 T 14-10-2018 C2I25_19280 8a64468a63a6049824875cbfc5e5b1d8 212 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 203 101.17 T 14-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 C2I25_19280 8a64468a63a6049824875cbfc5e5b1d8 212 SUPERFAMILY SSF53639 5 201 2.75E-44 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I25_19280 8a64468a63a6049824875cbfc5e5b1d8 212 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 11 199 4.6E-63 T 14-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 C2I25_19280 8a64468a63a6049824875cbfc5e5b1d8 212 SMART SM01007 9 195 2.7E-39 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I25_19280 8a64468a63a6049824875cbfc5e5b1d8 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 193 4.3E-39 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I25_19280 8a64468a63a6049824875cbfc5e5b1d8 212 Gene3D G3DSA:3.40.225.10 7 206 5.3E-49 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I25_25540 8839e14ee7f430c0570d455113aec6bb 111 Gene3D G3DSA:3.20.170.20 1 110 4.1E-30 T 14-10-2018 C2I25_25540 8839e14ee7f430c0570d455113aec6bb 111 Pfam PF06108 Protein of unknown function (DUF952) 6 93 1.2E-22 T 14-10-2018 IPR009297 Protein of unknown function DUF952 C2I25_25540 8839e14ee7f430c0570d455113aec6bb 111 SUPERFAMILY SSF56399 2 105 6.91E-28 T 14-10-2018 C2I25_04160 0fc48c503a222d121cf009777f7f797f 170 SUPERFAMILY SSF51206 3 113 1.96E-19 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like C2I25_04160 0fc48c503a222d121cf009777f7f797f 170 Gene3D G3DSA:2.60.120.1460 2 168 4.4E-25 T 14-10-2018 C2I25_04160 0fc48c503a222d121cf009777f7f797f 170 SUPERFAMILY SSF46785 120 163 7.26E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_04160 0fc48c503a222d121cf009777f7f797f 170 Pfam PF00027 Cyclic nucleotide-binding domain 3 81 2.0E-10 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_13475 c18b8ef40a6561511c75bbd81b9b3fc0 289 Gene3D G3DSA:3.30.240.20 84 157 1.5E-23 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_13475 c18b8ef40a6561511c75bbd81b9b3fc0 289 Gene3D G3DSA:3.30.240.20 173 231 3.8E-13 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_13475 c18b8ef40a6561511c75bbd81b9b3fc0 289 Pfam PF07870 Protein of unknown function (DUF1657) 240 283 1.8E-15 T 14-10-2018 IPR012452 Protein of unknown function DUF1657 C2I25_13475 c18b8ef40a6561511c75bbd81b9b3fc0 289 Pfam PF04239 Protein of unknown function (DUF421) 92 206 5.4E-32 T 14-10-2018 IPR007353 Protein of unknown function DUF421 C2I25_06235 4d647e330d9e67085a8f7dc89573be99 177 SUPERFAMILY SSF88946 12 101 1.88E-22 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_06235 4d647e330d9e67085a8f7dc89573be99 177 Pfam PF08281 Sigma-70, region 4 119 171 7.4E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_06235 4d647e330d9e67085a8f7dc89573be99 177 SUPERFAMILY SSF88659 115 177 4.67E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_06235 4d647e330d9e67085a8f7dc89573be99 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 174 1.3E-31 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_06235 4d647e330d9e67085a8f7dc89573be99 177 Gene3D G3DSA:1.10.10.10 98 177 1.7E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_06235 4d647e330d9e67085a8f7dc89573be99 177 Pfam PF04542 Sigma-70 region 2 23 84 8.8E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_06235 4d647e330d9e67085a8f7dc89573be99 177 Gene3D G3DSA:1.10.1740.10 1 97 6.0E-25 T 14-10-2018 C2I25_23425 0820e81e5a4bc73f47997fd460df90b5 796 SUPERFAMILY SSF56235 54 790 9.77E-230 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_23425 0820e81e5a4bc73f47997fd460df90b5 796 PIRSF PIRSF001227 15 795 7.2E-210 T 14-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 C2I25_23425 0820e81e5a4bc73f47997fd460df90b5 796 Gene3D G3DSA:1.10.439.10 29 193 9.5E-56 T 14-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 C2I25_23425 0820e81e5a4bc73f47997fd460df90b5 796 Pfam PF01804 Penicillin amidase 58 786 5.7E-226 T 14-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 C2I25_23425 0820e81e5a4bc73f47997fd460df90b5 796 Gene3D G3DSA:3.60.20.10 257 774 3.0E-171 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_23425 0820e81e5a4bc73f47997fd460df90b5 796 Gene3D G3DSA:1.10.1400.10 551 683 3.0E-171 T 14-10-2018 C2I25_23425 0820e81e5a4bc73f47997fd460df90b5 796 Gene3D G3DSA:2.30.120.10 329 402 3.0E-171 T 14-10-2018 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 Gene3D G3DSA:1.10.10.60 62 118 3.8E-17 T 14-10-2018 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 SUPERFAMILY SSF46689 65 115 3.58E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 Gene3D G3DSA:1.10.10.60 3 61 1.7E-16 T 14-10-2018 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 SUPERFAMILY SSF55136 135 294 1.73E-36 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 SMART SM00871 136 294 2.9E-35 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 Pfam PF14526 Integron-associated effector binding protein 139 293 4.0E-32 T 14-10-2018 IPR029441 Integron-associated effector binding protein C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 65 108 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 Pfam PF12833 Helix-turn-helix domain 34 114 5.2E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 SUPERFAMILY SSF46689 12 62 2.11E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 81 96 2.5E-7 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 96 112 2.5E-7 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 Gene3D G3DSA:3.20.80.10 137 295 1.2E-41 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_24375 f27c9eae54c7915588b85443814a3eee 296 SMART SM00342 28 112 4.4E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 Gene3D G3DSA:3.30.450.20 188 275 1.9E-27 T 14-10-2018 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 Pfam PF00672 HAMP domain 307 354 8.8E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 SUPERFAMILY SSF58104 327 663 4.32E-71 T 14-10-2018 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 Pfam PF02743 Cache domain 40 269 9.2E-29 T 14-10-2018 IPR033479 Double Cache domain 1 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 Gene3D G3DSA:1.10.287.950 368 663 2.3E-65 T 14-10-2018 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 Gene3D G3DSA:1.20.1480.50 276 366 2.4E-17 T 14-10-2018 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 SMART SM00283 388 663 1.5E-67 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 SUPERFAMILY SSF103190 99 198 4.71E-7 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_14015 80fbd20f34eda9effb1115061f806052 666 SMART SM00304 307 359 2.1E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 486 513 8.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 409 438 8.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 515 544 8.1E-22 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 462 606 6.6E-37 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_14015 80fbd20f34eda9effb1115061f806052 666 Gene3D G3DSA:3.30.450.20 93 187 1.9E-27 T 14-10-2018 C2I25_26160 406da50b402894c96d7fb45c3595dc05 402 SUPERFAMILY SSF103473 7 393 5.75E-50 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_26160 406da50b402894c96d7fb45c3595dc05 402 Gene3D G3DSA:1.20.1250.20 1 393 6.4E-43 T 14-10-2018 C2I25_26160 406da50b402894c96d7fb45c3595dc05 402 Pfam PF07690 Major Facilitator Superfamily 20 323 2.1E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_19070 f1aa75b5f82e22ce64b1879824dd73dc 139 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 4.6E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_19070 f1aa75b5f82e22ce64b1879824dd73dc 139 SUPERFAMILY SSF46785 6 78 1.31E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19070 f1aa75b5f82e22ce64b1879824dd73dc 139 Gene3D G3DSA:1.10.10.10 9 131 9.1E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19070 f1aa75b5f82e22ce64b1879824dd73dc 139 SMART SM00345 17 76 9.1E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_27055 03ab80ddf68db753316cc5a8244a167b 231 Pfam PF00072 Response regulator receiver domain 5 114 2.2E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_27055 03ab80ddf68db753316cc5a8244a167b 231 SMART SM00448 3 113 3.5E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_27055 03ab80ddf68db753316cc5a8244a167b 231 Gene3D G3DSA:1.10.10.10 130 231 3.2E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_27055 03ab80ddf68db753316cc5a8244a167b 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 5.6E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_27055 03ab80ddf68db753316cc5a8244a167b 231 SMART SM00862 153 229 1.2E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_27055 03ab80ddf68db753316cc5a8244a167b 231 Gene3D G3DSA:3.40.50.2300 1 129 2.3E-37 T 14-10-2018 C2I25_27055 03ab80ddf68db753316cc5a8244a167b 231 SUPERFAMILY SSF52172 2 129 6.97E-41 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_27055 03ab80ddf68db753316cc5a8244a167b 231 SUPERFAMILY SSF46894 128 229 2.3E-29 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 Pfam PF00989 PAS fold 113 198 2.8E-9 T 14-10-2018 IPR013767 PAS fold GO:0006355 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 1.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 533 1.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 571 1.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 552 1.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 Pfam PF08448 PAS fold 245 348 2.8E-17 T 14-10-2018 IPR013656 PAS fold-4 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 SMART SM00091 113 182 2.1E-6 T 14-10-2018 IPR000014 PAS domain C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 SMART SM00091 239 305 0.85 T 14-10-2018 IPR000014 PAS domain C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 SUPERFAMILY SSF47384 358 423 7.46E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 SUPERFAMILY SSF55785 108 225 2.62E-14 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 Gene3D G3DSA:3.30.565.10 424 579 1.3E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 Gene3D G3DSA:1.10.287.130 365 421 4.9E-16 T 14-10-2018 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 SMART SM00387 467 574 1.5E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 Gene3D G3DSA:3.30.450.20 237 358 2.9E-15 T 14-10-2018 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 SUPERFAMILY SSF55785 224 345 6.0E-14 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 Gene3D G3DSA:3.30.450.20 110 236 1.4E-14 T 14-10-2018 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 SUPERFAMILY SSF55874 416 573 1.3E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 110 234 7.4E-12 T 14-10-2018 IPR000014 PAS domain C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 572 8.1E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 423 1.2E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_26430 fce724303dbd1dec56c1756e4103eb50 595 SMART SM00388 362 425 6.9E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_06900 5ae58e8755d4e24d07bc1e06e0b3ddf5 530 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 337 516 3.2E-48 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_06900 5ae58e8755d4e24d07bc1e06e0b3ddf5 530 SUPERFAMILY SSF53187 335 521 8.79E-50 T 14-10-2018 C2I25_06900 5ae58e8755d4e24d07bc1e06e0b3ddf5 530 Gene3D G3DSA:3.40.630.40 333 525 5.6E-57 T 14-10-2018 C2I25_06900 5ae58e8755d4e24d07bc1e06e0b3ddf5 530 Pfam PF00395 S-layer homology domain 28 71 1.7E-14 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06900 5ae58e8755d4e24d07bc1e06e0b3ddf5 530 Pfam PF00395 S-layer homology domain 151 192 2.3E-7 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06900 5ae58e8755d4e24d07bc1e06e0b3ddf5 530 Pfam PF00395 S-layer homology domain 89 131 4.8E-10 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06900 5ae58e8755d4e24d07bc1e06e0b3ddf5 530 SMART SM00646 402 516 3.0E-40 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 1.8E-83 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.5E-180 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 SMART SM01003 4 136 1.2E-77 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 6.3E-47 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 SMART SM01002 148 297 4.2E-90 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 Gene3D G3DSA:3.40.50.720 129 305 4.8E-141 T 14-10-2018 C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 Gene3D G3DSA:3.40.50.720 3 353 4.8E-141 T 14-10-2018 C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 SUPERFAMILY SSF51735 136 303 2.05E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 SUPERFAMILY SSF52283 1 360 2.13E-67 T 14-10-2018 C2I25_08525 ed3d3d437e66009179599d14a8843c57 377 PIRSF PIRSF000183 1 371 3.0E-192 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 14-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 Gene3D G3DSA:1.10.10.60 138 186 2.3E-5 T 14-10-2018 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 Pfam PF00239 Resolvase, N terminal domain 2 135 6.3E-46 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 SUPERFAMILY SSF53041 1 135 4.97E-45 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 SUPERFAMILY SSF46689 138 185 8.51E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 Pfam PF02796 Helix-turn-helix domain of resolvase 138 181 5.0E-13 T 14-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 SMART SM00857 2 136 1.7E-57 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I25_00760 715231151e7d31202b52f408f3fd5444 190 Gene3D G3DSA:3.40.50.1390 1 124 1.5E-49 T 14-10-2018 C2I25_00975 6eeae6356785b08040543b872da30c09 474 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 238 1.3E-90 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_00975 6eeae6356785b08040543b872da30c09 474 Gene3D G3DSA:3.40.1010.10 1 118 3.0E-41 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I25_00975 6eeae6356785b08040543b872da30c09 474 SUPERFAMILY SSF53790 1 252 1.19E-74 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I25_00975 6eeae6356785b08040543b872da30c09 474 SUPERFAMILY SSF69618 252 329 1.96E-6 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_00975 6eeae6356785b08040543b872da30c09 474 PIRSF PIRSF036426 1 255 2.2E-96 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_00975 6eeae6356785b08040543b872da30c09 474 Gene3D G3DSA:3.30.950.10 119 268 9.5E-45 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I25_00975 6eeae6356785b08040543b872da30c09 474 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 83 116 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_00975 6eeae6356785b08040543b872da30c09 474 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 214 8.0E-43 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 SUPERFAMILY SSF55653 57 147 3.66E-28 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 Gene3D G3DSA:3.10.430.100 60 148 3.2E-32 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 Gene3D G3DSA:3.40.5.10 1 52 7.8E-25 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 9.4E-22 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 5.3E-30 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 SUPERFAMILY SSF55658 1 56 6.98E-18 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.2E-50 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11745 2ae912f391671dfc7b151f15508ce296 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.086 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_24105 4fc7b2ff63a4d5ae14484f277c2b135c 377 SUPERFAMILY SSF50129 1 176 1.14E-60 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_24105 4fc7b2ff63a4d5ae14484f277c2b135c 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 1.9E-30 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_24105 4fc7b2ff63a4d5ae14484f277c2b135c 377 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 7.7E-11 T 14-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated C2I25_24105 4fc7b2ff63a4d5ae14484f277c2b135c 377 Pfam PF00107 Zinc-binding dehydrogenase 188 255 3.1E-10 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_24105 4fc7b2ff63a4d5ae14484f277c2b135c 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 C2I25_24105 4fc7b2ff63a4d5ae14484f277c2b135c 377 Gene3D G3DSA:3.90.180.10 4 364 3.0E-125 T 14-10-2018 C2I25_24105 4fc7b2ff63a4d5ae14484f277c2b135c 377 SUPERFAMILY SSF51735 155 338 3.16E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_24105 4fc7b2ff63a4d5ae14484f277c2b135c 377 Gene3D G3DSA:3.40.50.720 168 337 3.0E-125 T 14-10-2018 C2I25_05375 f36ccd4e0b84b2f1bdbf22164a74eb85 246 SUPERFAMILY SSF56300 1 220 9.74E-41 T 14-10-2018 C2I25_05375 f36ccd4e0b84b2f1bdbf22164a74eb85 246 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 9.6E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_05375 f36ccd4e0b84b2f1bdbf22164a74eb85 246 Hamap MF_01443 Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical] [prpE]. 1 246 63.225 T 14-10-2018 IPR023937 Bis(5'-nucleosyl)-tetraphosphatase PrpE GO:0004081|GO:0016151 KEGG: 00230+3.6.1.17|KEGG: 00240+3.6.1.17 C2I25_05375 f36ccd4e0b84b2f1bdbf22164a74eb85 246 Gene3D G3DSA:3.60.21.10 1 241 4.7E-61 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_06225 f6449f5effb5269da8bed62c89bfa3d1 417 Pfam PF01098 Cell cycle protein 80 407 7.1E-30 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_23375 8263c6a1061ef3411753a5000c7588dc 398 Gene3D G3DSA:1.20.1250.20 2 187 5.2E-24 T 14-10-2018 C2I25_23375 8263c6a1061ef3411753a5000c7588dc 398 Pfam PF07690 Major Facilitator Superfamily 13 236 3.3E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_23375 8263c6a1061ef3411753a5000c7588dc 398 Gene3D G3DSA:1.20.1250.20 192 396 1.5E-24 T 14-10-2018 C2I25_23375 8263c6a1061ef3411753a5000c7588dc 398 SUPERFAMILY SSF103473 5 381 6.8E-53 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_26465 941fdeb5bcc0719cc553e585172e01b6 427 Gene3D G3DSA:1.20.1250.20 16 406 4.0E-38 T 14-10-2018 C2I25_26465 941fdeb5bcc0719cc553e585172e01b6 427 SUPERFAMILY SSF103473 19 406 1.28E-47 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_26465 941fdeb5bcc0719cc553e585172e01b6 427 Pfam PF07690 Major Facilitator Superfamily 30 241 1.5E-19 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_27780 009199cef2f9b4d215ef26d1c70461a3 210 Pfam PF00190 Cupin 32 131 4.1E-10 T 14-10-2018 IPR006045 Cupin 1 GO:0045735 C2I25_27780 009199cef2f9b4d215ef26d1c70461a3 210 SMART SM00835 21 158 6.4E-14 T 14-10-2018 IPR006045 Cupin 1 GO:0045735 C2I25_27780 009199cef2f9b4d215ef26d1c70461a3 210 SUPERFAMILY SSF51182 30 173 4.03E-27 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_27780 009199cef2f9b4d215ef26d1c70461a3 210 Gene3D G3DSA:2.60.120.10 2 173 2.1E-25 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_03170 abc9bff8107c9bd2dfc5a6c278f81fba 287 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 163 9.0E-49 T 14-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 C2I25_03170 abc9bff8107c9bd2dfc5a6c278f81fba 287 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 1.2E-10 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_03170 abc9bff8107c9bd2dfc5a6c278f81fba 287 Pfam PF00700 Bacterial flagellin C-terminal helical region 212 287 4.9E-6 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_03170 abc9bff8107c9bd2dfc5a6c278f81fba 287 SUPERFAMILY SSF64518 1 287 1.31E-47 T 14-10-2018 C2I25_03170 abc9bff8107c9bd2dfc5a6c278f81fba 287 Gene3D G3DSA:1.20.1330.10 39 234 9.6E-42 T 14-10-2018 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 Gene3D G3DSA:1.10.580.10 33 357 2.3E-112 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 Gene3D G3DSA:1.10.230.10 225 324 2.3E-112 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 PIRSF PIRSF001369 1 371 2.8E-139 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 330 344 3.2E-34 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 177 192 3.2E-34 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 252 272 3.2E-34 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 128 141 3.2E-34 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 199 227 3.2E-34 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 310 326 3.2E-34 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 ProSitePatterns PS00480 Citrate synthase signature. 259 272 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 SUPERFAMILY SSF48256 6 367 1.31E-121 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 C2I25_28260 c73ee89eb1632a96832c7e5d0ae76ef4 372 Pfam PF00285 Citrate synthase, C-terminal domain 10 360 5.6E-114 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_15565 7b32ab2f15c833cde1f1a27cb85aa09a 140 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 14 93 9.7E-24 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 C2I25_15565 7b32ab2f15c833cde1f1a27cb85aa09a 140 Gene3D G3DSA:1.10.3420.10 57 137 1.8E-37 T 14-10-2018 IPR023292 NTP pyrophosphohydrolase-like domain superfamily C2I25_15565 7b32ab2f15c833cde1f1a27cb85aa09a 140 Gene3D G3DSA:1.10.3420.10 5 56 3.3E-9 T 14-10-2018 IPR023292 NTP pyrophosphohydrolase-like domain superfamily C2I25_14920 76adaeb8f991284b4b7cfdadbde5e494 232 SMART SM00862 154 230 2.6E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_14920 76adaeb8f991284b4b7cfdadbde5e494 232 Gene3D G3DSA:1.10.10.10 131 232 2.0E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_14920 76adaeb8f991284b4b7cfdadbde5e494 232 SUPERFAMILY SSF52172 1 189 1.57E-44 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_14920 76adaeb8f991284b4b7cfdadbde5e494 232 Gene3D G3DSA:3.40.50.2300 1 130 7.5E-41 T 14-10-2018 C2I25_14920 76adaeb8f991284b4b7cfdadbde5e494 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 2.3E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_14920 76adaeb8f991284b4b7cfdadbde5e494 232 SMART SM00448 4 114 3.3E-46 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_14920 76adaeb8f991284b4b7cfdadbde5e494 232 Pfam PF00072 Response regulator receiver domain 6 115 6.6E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_07705 8e669eed3f2b310bc631be45bd93dcd0 256 Gene3D G3DSA:3.20.20.70 1 256 8.8E-114 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_07705 8e669eed3f2b310bc631be45bd93dcd0 256 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 41.674 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 C2I25_07705 8e669eed3f2b310bc631be45bd93dcd0 256 SUPERFAMILY SSF110399 1 239 8.37E-80 T 14-10-2018 C2I25_07705 8e669eed3f2b310bc631be45bd93dcd0 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 5 248 4.4E-107 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 C2I25_22460 ae9ca020debb8f5544b9d73916172371 230 SUPERFAMILY SSF46785 151 226 1.25E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22460 ae9ca020debb8f5544b9d73916172371 230 Gene3D G3DSA:1.10.10.10 151 227 2.8E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22460 ae9ca020debb8f5544b9d73916172371 230 Gene3D G3DSA:2.60.120.10 9 146 6.9E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_22460 ae9ca020debb8f5544b9d73916172371 230 SUPERFAMILY SSF51206 21 140 1.57E-26 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like C2I25_22460 ae9ca020debb8f5544b9d73916172371 230 Pfam PF00027 Cyclic nucleotide-binding domain 35 117 8.3E-13 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_22460 ae9ca020debb8f5544b9d73916172371 230 Pfam PF13545 Crp-like helix-turn-helix domain 154 224 2.3E-7 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I25_00795 7b246e8d38b8c74e26656dd34577ac7d 349 SUPERFAMILY SSF56219 24 348 6.15E-28 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_00795 7b246e8d38b8c74e26656dd34577ac7d 349 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 35 338 1.0E-12 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase C2I25_00795 7b246e8d38b8c74e26656dd34577ac7d 349 Gene3D G3DSA:3.60.10.10 27 345 5.0E-35 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_06475 2a9014e2fac280c825b27eeb42c6cddb 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 9 32 3.5E-12 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_06475 2a9014e2fac280c825b27eeb42c6cddb 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 11 34 1.2E-10 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_21300 d8153f435cd67ca0f3406f9c1125216e 150 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 18 137 4.8E-28 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_21300 d8153f435cd67ca0f3406f9c1125216e 150 Gene3D G3DSA:3.40.80.10 10 148 1.6E-40 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_21300 d8153f435cd67ca0f3406f9c1125216e 150 SMART SM00701 1 129 3.2E-8 T 14-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_21300 d8153f435cd67ca0f3406f9c1125216e 150 SUPERFAMILY SSF55846 14 140 1.44E-38 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_21300 d8153f435cd67ca0f3406f9c1125216e 150 SMART SM00644 9 137 9.2E-17 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_17520 18c68029eb22776c08262e4d4aaf295e 200 Gene3D G3DSA:3.40.50.1240 1 199 4.4E-21 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_17520 18c68029eb22776c08262e4d4aaf295e 200 SMART SM00855 2 166 6.1E-6 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_17520 18c68029eb22776c08262e4d4aaf295e 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 73 1.8E-10 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_17520 18c68029eb22776c08262e4d4aaf295e 200 SUPERFAMILY SSF53254 1 193 6.55E-20 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_03015 1b4f73c660cd4f4cb0ad6f987fbad095 348 Pfam PF01312 FlhB HrpN YscU SpaS Family 5 339 1.2E-110 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I25_03015 1b4f73c660cd4f4cb0ad6f987fbad095 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 265 280 5.8E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I25_03015 1b4f73c660cd4f4cb0ad6f987fbad095 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 295 316 5.8E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I25_03015 1b4f73c660cd4f4cb0ad6f987fbad095 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 7 29 5.8E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I25_03015 1b4f73c660cd4f4cb0ad6f987fbad095 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 221 238 5.8E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I25_03015 1b4f73c660cd4f4cb0ad6f987fbad095 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 201 219 5.8E-37 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I25_03015 1b4f73c660cd4f4cb0ad6f987fbad095 348 SUPERFAMILY SSF160544 237 344 3.66E-33 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal C2I25_03015 1b4f73c660cd4f4cb0ad6f987fbad095 348 Gene3D G3DSA:3.40.1690.10 211 347 1.9E-47 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal C2I25_03990 922a921c0ab99fa50c504c5d19b060f7 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 3.8E-21 T 14-10-2018 C2I25_03990 922a921c0ab99fa50c504c5d19b060f7 82 Gene3D G3DSA:3.30.70.20 2 82 2.3E-34 T 14-10-2018 C2I25_03990 922a921c0ab99fa50c504c5d19b060f7 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.9E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I25_03990 922a921c0ab99fa50c504c5d19b060f7 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 2.9E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I25_03990 922a921c0ab99fa50c504c5d19b060f7 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.9E-8 T 14-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I25_03990 922a921c0ab99fa50c504c5d19b060f7 82 SUPERFAMILY SSF54862 4 72 1.82E-13 T 14-10-2018 C2I25_11470 9c6ad6d099d2645e96a3ebf5cfa2cf33 59 Pfam PF10764 Inhibitor of sigma-G Gin 8 52 2.4E-18 T 14-10-2018 IPR019700 Anti-sigma-G factor Gin C2I25_17490 9256c85dc347f1b870f1fd72fec4408d 104 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 93 5.7E-23 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 C2I25_17490 9256c85dc347f1b870f1fd72fec4408d 104 Gene3D G3DSA:3.30.1360.20 3 101 2.2E-29 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 C2I25_17490 9256c85dc347f1b870f1fd72fec4408d 104 SUPERFAMILY SSF55248 4 94 1.96E-25 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 SMART SM00267 135 302 5.9E-56 T 14-10-2018 IPR000160 GGDEF domain C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 Gene3D G3DSA:3.30.450.20 12 144 6.6E-36 T 14-10-2018 C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 SUPERFAMILY SSF55785 26 125 2.79E-31 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 SMART SM00052 312 558 2.1E-93 T 14-10-2018 IPR001633 EAL domain C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 Pfam PF00990 Diguanylate cyclase, GGDEF domain 146 297 6.3E-42 T 14-10-2018 IPR000160 GGDEF domain C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 144 299 4.0E-36 T 14-10-2018 IPR000160 GGDEF domain C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 Gene3D G3DSA:3.30.70.270 145 315 1.3E-56 T 14-10-2018 C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 Pfam PF13426 PAS domain 26 126 3.9E-16 T 14-10-2018 IPR000014 PAS domain C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 135 4.9E-19 T 14-10-2018 IPR000014 PAS domain C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 Gene3D G3DSA:3.20.20.450 316 566 1.2E-90 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 SUPERFAMILY SSF141868 319 563 8.37E-85 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 SUPERFAMILY SSF55073 151 304 4.87E-46 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 Pfam PF00563 EAL domain 319 553 3.4E-70 T 14-10-2018 IPR001633 EAL domain C2I25_08350 e8689ee9cf5f2e5d7c4da00864933781 567 SMART SM00086 86 128 9.4E-11 T 14-10-2018 IPR001610 PAC motif C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 4.3E-185 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 SUPERFAMILY SSF53448 5 307 2.7E-66 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 2.0E-6 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 2.1E-7 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 300 7.8E-9 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 SUPERFAMILY SSF51161 254 446 1.74E-51 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 Pfam PF00483 Nucleotidyl transferase 6 211 2.2E-25 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 Gene3D G3DSA:3.90.550.10 1 252 3.4E-78 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.813 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 C2I25_11365 c8b6232b7a07537139ee6d1a7278113d 459 Gene3D G3DSA:2.160.10.10 253 439 5.9E-54 T 14-10-2018 C2I25_10315 5e58d52d2c35efa86e174aeff5256ad1 390 Pfam PF04209 homogentisate 1,2-dioxygenase 103 382 2.7E-19 T 14-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 C2I25_10315 5e58d52d2c35efa86e174aeff5256ad1 390 SUPERFAMILY SSF51182 5 382 6.41E-100 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_10315 5e58d52d2c35efa86e174aeff5256ad1 390 Gene3D G3DSA:2.60.120.10 78 175 4.3E-8 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_10315 5e58d52d2c35efa86e174aeff5256ad1 390 Gene3D G3DSA:2.60.120.10 267 360 1.5E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.1E-35 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.1E-35 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.1E-35 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.1E-35 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00097 Anthranilate synthase component II signature 165 178 4.1E-35 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.1E-35 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 3.3E-70 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 Pfam PF00117 Glutamine amidotransferase class-I 3 188 2.4E-53 T 14-10-2018 IPR017926 Glutamine amidotransferase C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 Gene3D G3DSA:3.40.50.880 1 188 1.0E-62 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.8E-14 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.8E-14 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.8E-14 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 SUPERFAMILY SSF52317 1 187 1.64E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.2E-8 T 14-10-2018 C2I25_05220 0980a9dc53438020f09ba78b54dbc748 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.2E-8 T 14-10-2018 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Gene3D G3DSA:3.30.450.40 246 412 3.1E-13 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 SMART SM00387 610 734 5.3E-38 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 SMART SM00448 776 890 2.7E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Gene3D G3DSA:1.20.1440.210 50 169 1.1E-11 T 14-10-2018 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Pfam PF05227 CHASE3 domain 46 172 2.1E-20 T 14-10-2018 IPR007891 CHASE3 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Gene3D G3DSA:1.10.287.130 460 561 1.5E-24 T 14-10-2018 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Pfam PF00072 Response regulator receiver domain 778 888 5.7E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 SMART SM00388 495 563 4.7E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Pfam PF00512 His Kinase A (phospho-acceptor) domain 496 563 9.5E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Gene3D G3DSA:3.30.565.10 562 733 2.0E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 SUPERFAMILY SSF55874 552 734 1.13E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Pfam PF13185 GAF domain 275 410 9.7E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Gene3D G3DSA:3.40.50.12740 775 894 1.6E-39 T 14-10-2018 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 610 731 1.1E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 SUPERFAMILY SSF55781 255 439 2.32E-22 T 14-10-2018 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 SUPERFAMILY SSF47384 481 564 2.35E-21 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 694 712 6.8E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 718 731 6.8E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 673 6.8E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 677 687 6.8E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_06410 a430e0bf337cfbbba3b857a115757f99 896 SUPERFAMILY SSF52172 773 893 1.18E-36 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_05785 5e0320379994403909b612fe7960d862 575 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 342 525 2.2E-48 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_05785 5e0320379994403909b612fe7960d862 575 SUPERFAMILY SSF58104 236 571 3.4E-71 T 14-10-2018 C2I25_05785 5e0320379994403909b612fe7960d862 575 SMART SM00304 216 268 1.2E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_05785 5e0320379994403909b612fe7960d862 575 SMART SM00283 297 572 5.0E-73 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_05785 5e0320379994403909b612fe7960d862 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 59 74 4.2E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_05785 5e0320379994403909b612fe7960d862 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 395 422 4.2E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_05785 5e0320379994403909b612fe7960d862 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 424 453 4.2E-21 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 C2I25_05785 5e0320379994403909b612fe7960d862 575 Pfam PF00672 HAMP domain 217 264 9.3E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_05785 5e0320379994403909b612fe7960d862 575 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 188 4.9E-15 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain C2I25_05785 5e0320379994403909b612fe7960d862 575 Gene3D G3DSA:1.10.287.950 222 572 1.5E-70 T 14-10-2018 C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 Gene3D G3DSA:3.10.20.580 450 556 1.5E-37 T 14-10-2018 C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 SUPERFAMILY SSF56281 10 424 5.66E-98 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 363 409 2.6E-11 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 Gene3D G3DSA:3.60.15.10 12 443 2.4E-185 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 Hamap MF_01491 Ribonuclease J [rnj]. 4 556 48.406 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 SMART SM00849 21 216 7.9E-24 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 PIRSF PIRSF004803 1 556 5.3E-244 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 2.1E-14 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 Gene3D G3DSA:3.40.50.10710 208 358 2.4E-185 T 14-10-2018 C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 365 393 - T 14-10-2018 IPR001587 Ribonuclease J, conserved site C2I25_20525 f996df28b480b6f2214d0a5064d97bf6 556 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 554 4.1E-214 T 14-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 C2I25_04300 942727d8a5c8029f6f61d63ef18e2801 234 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 37 209 2.5E-49 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 C2I25_04300 942727d8a5c8029f6f61d63ef18e2801 234 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 233 42.181 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 C2I25_04300 942727d8a5c8029f6f61d63ef18e2801 234 SUPERFAMILY SSF52402 16 197 1.67E-50 T 14-10-2018 C2I25_04300 942727d8a5c8029f6f61d63ef18e2801 234 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 43 231 3.7E-71 T 14-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 C2I25_04300 942727d8a5c8029f6f61d63ef18e2801 234 Gene3D G3DSA:3.40.50.620 6 234 5.1E-74 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_04300 942727d8a5c8029f6f61d63ef18e2801 234 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 24 232 1.5E-87 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 C2I25_04300 942727d8a5c8029f6f61d63ef18e2801 234 PIRSF PIRSF000857 3 234 8.0E-88 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 C2I25_06720 d401b32c57ffb8f7facc73e2b90db8ed 431 Gene3D G3DSA:3.40.50.300 148 431 2.2E-101 T 14-10-2018 C2I25_06720 d401b32c57ffb8f7facc73e2b90db8ed 431 SUPERFAMILY SSF48024 6 105 2.35E-20 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 C2I25_06720 d401b32c57ffb8f7facc73e2b90db8ed 431 Pfam PF03796 DnaB-like helicase C terminal domain 171 428 1.3E-92 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 C2I25_06720 d401b32c57ffb8f7facc73e2b90db8ed 431 Pfam PF00772 DnaB-like helicase N terminal domain 7 102 1.7E-19 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 C2I25_06720 d401b32c57ffb8f7facc73e2b90db8ed 431 Gene3D G3DSA:1.10.860.10 1 143 2.6E-31 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal C2I25_06720 d401b32c57ffb8f7facc73e2b90db8ed 431 SUPERFAMILY SSF52540 169 423 1.11E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_06720 d401b32c57ffb8f7facc73e2b90db8ed 431 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 6 429 2.1E-124 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 C2I25_08285 90d8b72355d46829b098d17aaa9f491a 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 109 9.5E-29 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I25_08285 90d8b72355d46829b098d17aaa9f491a 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 211 5.1E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_08285 90d8b72355d46829b098d17aaa9f491a 214 SUPERFAMILY SSF161098 15 209 3.01E-44 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_08285 90d8b72355d46829b098d17aaa9f491a 214 Gene3D G3DSA:1.10.3720.10 10 214 1.1E-51 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_26275 4bf9868eea3f6d728a6187ebe2c8575f 141 Pfam PF07366 SnoaL-like polyketide cyclase 7 134 2.3E-26 T 14-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 C2I25_26275 4bf9868eea3f6d728a6187ebe2c8575f 141 Gene3D G3DSA:3.10.450.50 2 137 1.4E-22 T 14-10-2018 C2I25_26275 4bf9868eea3f6d728a6187ebe2c8575f 141 SUPERFAMILY SSF54427 3 134 9.61E-27 T 14-10-2018 IPR032710 NTF2-like domain superfamily C2I25_05810 58d5a0972dd8fdfd521cdeb8d7dbef3f 234 SUPERFAMILY SSF46894 129 232 1.39E-27 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_05810 58d5a0972dd8fdfd521cdeb8d7dbef3f 234 Gene3D G3DSA:1.10.10.10 133 234 2.5E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_05810 58d5a0972dd8fdfd521cdeb8d7dbef3f 234 SUPERFAMILY SSF52172 3 126 8.11E-37 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_05810 58d5a0972dd8fdfd521cdeb8d7dbef3f 234 SMART SM00448 4 115 3.8E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_05810 58d5a0972dd8fdfd521cdeb8d7dbef3f 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 231 2.7E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_05810 58d5a0972dd8fdfd521cdeb8d7dbef3f 234 Pfam PF00072 Response regulator receiver domain 6 115 4.1E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_05810 58d5a0972dd8fdfd521cdeb8d7dbef3f 234 SMART SM00862 154 231 1.2E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_05810 58d5a0972dd8fdfd521cdeb8d7dbef3f 234 Gene3D G3DSA:3.40.50.2300 2 132 1.8E-34 T 14-10-2018 C2I25_10010 23d88d51a558a0d3ba1324e79209d520 290 Pfam PF08241 Methyltransferase domain 89 185 1.2E-14 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_10010 23d88d51a558a0d3ba1324e79209d520 290 Gene3D G3DSA:3.40.50.150 46 239 9.9E-26 T 14-10-2018 C2I25_10010 23d88d51a558a0d3ba1324e79209d520 290 SUPERFAMILY SSF53335 70 232 4.41E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_15300 dca1f488626c7e6fa8a6d3a0e124b444 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 259 1.8E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_15300 dca1f488626c7e6fa8a6d3a0e124b444 268 Gene3D G3DSA:1.10.3720.10 64 261 1.5E-24 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_15300 dca1f488626c7e6fa8a6d3a0e124b444 268 SUPERFAMILY SSF161098 67 249 7.59E-30 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 Pfam PF02274 Amidinotransferase 19 407 1.0E-113 T 14-10-2018 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 Gene3D G3DSA:1.10.3930.10 69 152 6.6E-163 T 14-10-2018 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 SUPERFAMILY SSF55909 1 410 7.67E-137 T 14-10-2018 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 Hamap MF_00242 Arginine deiminase [arcA]. 2 410 48.152 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 PRINTS PR01466 Bacterial arginine deiminase signature 152 170 6.1E-58 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 PRINTS PR01466 Bacterial arginine deiminase signature 389 407 6.1E-58 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 PRINTS PR01466 Bacterial arginine deiminase signature 180 195 6.1E-58 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 PRINTS PR01466 Bacterial arginine deiminase signature 346 363 6.1E-58 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 PRINTS PR01466 Bacterial arginine deiminase signature 366 380 6.1E-58 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 6.1E-58 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 TIGRFAM TIGR01078 arcA: arginine deiminase 5 410 2.1E-168 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 PIRSF PIRSF006356 1 410 1.2E-163 T 14-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 C2I25_09490 98279a0560ff076d9f5b801dc4d6ba18 410 Gene3D G3DSA:3.75.10.10 6 405 6.6E-163 T 14-10-2018 C2I25_25070 861d392e7d9109f37465fcb30634d581 273 SUPERFAMILY SSF53067 5 271 9.96E-55 T 14-10-2018 C2I25_25070 861d392e7d9109f37465fcb30634d581 273 PIRSF PIRSF036940 1 272 7.1E-133 T 14-10-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 C2I25_25070 861d392e7d9109f37465fcb30634d581 273 Pfam PF03630 Fumble 5 269 3.4E-34 T 14-10-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 C2I25_25070 861d392e7d9109f37465fcb30634d581 273 Gene3D G3DSA:3.30.420.40 5 268 1.0E-86 T 14-10-2018 C2I25_25070 861d392e7d9109f37465fcb30634d581 273 TIGRFAM TIGR00555 panK_eukar: pantothenate kinase 4 269 1.9E-85 T 14-10-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 C2I25_25070 861d392e7d9109f37465fcb30634d581 273 Gene3D G3DSA:3.30.420.40 76 256 1.0E-86 T 14-10-2018 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 Gene3D G3DSA:3.40.50.300 25 266 4.7E-81 T 14-10-2018 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 SMART SM00382 56 227 3.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 321 3.1E-174 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 Pfam PF00154 recA bacterial DNA recombination protein 7 267 7.1E-146 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 Gene3D G3DSA:3.30.250.10 267 341 9.6E-27 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 ProSitePatterns PS00321 recA signature. 212 220 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 Hamap MF_00268 Protein RecA [recA]. 4 328 52.836 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 92 121 1.2E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 242 271 1.2E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 296 313 1.2E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 209 237 1.2E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 164 193 1.2E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 126 155 1.2E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 SUPERFAMILY SSF54752 267 325 7.72E-21 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal C2I25_20615 d4a8c22acea0bd6832bd18d60545ebf4 343 SUPERFAMILY SSF52540 3 266 4.24E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25810 152914b2473b15875a0cf8ef999fb212 279 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 17 279 41.988 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 C2I25_25810 152914b2473b15875a0cf8ef999fb212 279 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 16 279 1.6E-133 T 14-10-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 C2I25_25810 152914b2473b15875a0cf8ef999fb212 279 Gene3D G3DSA:1.20.58.480 20 279 5.2E-101 T 14-10-2018 C2I25_25810 152914b2473b15875a0cf8ef999fb212 279 SUPERFAMILY SSF140959 22 279 2.09E-102 T 14-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 C2I25_25810 152914b2473b15875a0cf8ef999fb212 279 Pfam PF03301 Tryptophan 2,3-dioxygenase 14 278 2.8E-69 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 C2I25_09900 460983f80807a224c43ea42b25a7d441 346 SUPERFAMILY SSF55326 3 167 9.87E-53 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I25_09900 460983f80807a224c43ea42b25a7d441 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 161 2.0E-18 T 14-10-2018 IPR016188 PurM-like, N-terminal domain C2I25_09900 460983f80807a224c43ea42b25a7d441 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 333 3.7E-143 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09900 460983f80807a224c43ea42b25a7d441 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 340 48.485 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09900 460983f80807a224c43ea42b25a7d441 346 SUPERFAMILY SSF56042 168 338 6.73E-58 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I25_09900 460983f80807a224c43ea42b25a7d441 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 338 7.7E-38 T 14-10-2018 IPR010918 PurM-like, C-terminal domain C2I25_09900 460983f80807a224c43ea42b25a7d441 346 Gene3D G3DSA:3.30.1330.10 1 167 9.0E-72 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I25_09900 460983f80807a224c43ea42b25a7d441 346 Gene3D G3DSA:3.90.650.10 168 346 3.2E-76 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I25_08265 490a7e12353e29244913ed228b585681 313 Pfam PF08279 HTH domain 6 61 3.3E-16 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 C2I25_08265 490a7e12353e29244913ed228b585681 313 SUPERFAMILY SSF46785 3 60 7.61E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08265 490a7e12353e29244913ed228b585681 313 Gene3D G3DSA:1.10.10.10 1 63 4.9E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_08265 490a7e12353e29244913ed228b585681 313 PIRSF PIRSF016838 2 313 1.2E-18 T 14-10-2018 IPR028349 Protein PafC C2I25_08265 490a7e12353e29244913ed228b585681 313 Pfam PF13280 WYL domain 139 307 6.0E-27 T 14-10-2018 IPR026881 WYL domain C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 SUPERFAMILY SSF54909 67 137 5.36E-15 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 Gene3D G3DSA:1.10.10.10 1 50 7.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 SMART SM00344 3 109 9.3E-38 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 Gene3D G3DSA:3.30.70.920 51 140 6.8E-21 T 14-10-2018 C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.4E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.4E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.4E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 9.9E-18 T 14-10-2018 C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 Pfam PF01037 Lrp/AsnC ligand binding domain 70 136 4.4E-12 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I25_04605 55906d2b9d1bc34fd370252407fe8194 150 SUPERFAMILY SSF46785 2 62 8.08E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01180 132abdf5785d486d3d8ccea303b20437 142 SUPERFAMILY SSF55729 1 138 1.52E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01180 132abdf5785d486d3d8ccea303b20437 142 Pfam PF00583 Acetyltransferase (GNAT) family 45 132 2.1E-14 T 14-10-2018 IPR000182 GNAT domain C2I25_01180 132abdf5785d486d3d8ccea303b20437 142 Gene3D G3DSA:3.40.630.30 1 140 1.8E-23 T 14-10-2018 C2I25_25465 020c2c040ba7547203ff78839e462e32 548 SUPERFAMILY SSF55486 20 545 1.52E-64 T 14-10-2018 C2I25_25465 020c2c040ba7547203ff78839e462e32 548 Pfam PF01432 Peptidase family M3 155 512 6.5E-30 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 C2I25_25465 020c2c040ba7547203ff78839e462e32 548 Gene3D G3DSA:1.10.1370.30 2 548 9.3E-120 T 14-10-2018 C2I25_25465 020c2c040ba7547203ff78839e462e32 548 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 3 548 8.4E-212 T 14-10-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 66 503 74.325 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 67 502 8.3E-201 T 14-10-2018 C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 Gene3D G3DSA:3.80.30.20 210 443 7.0E-91 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 215 235 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 SMART SM00729 211 429 5.4E-66 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 Pfam PF04055 Radical SAM superfamily 215 386 5.4E-33 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 Pfam PF00919 Uncharacterized protein family UPF0004 67 168 2.5E-30 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 SUPERFAMILY SSF102114 198 431 1.57E-64 T 14-10-2018 C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 Pfam PF01938 TRAM domain 441 502 4.0E-13 T 14-10-2018 IPR002792 TRAM domain C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 67 499 6.9E-162 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 C2I25_20655 4bc9ccdb6de5e567fa2d1f8f252cf4ff 509 Gene3D G3DSA:3.40.50.12160 66 201 1.9E-34 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily C2I25_03815 59151f88828dea9b63716ca87c250a32 361 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 349 4.2E-110 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 C2I25_03815 59151f88828dea9b63716ca87c250a32 361 SUPERFAMILY SSF56796 7 356 1.44E-97 T 14-10-2018 C2I25_03815 59151f88828dea9b63716ca87c250a32 361 Gene3D G3DSA:1.20.1090.10 173 358 3.5E-52 T 14-10-2018 C2I25_03815 59151f88828dea9b63716ca87c250a32 361 Gene3D G3DSA:3.40.50.1970 2 172 5.4E-58 T 14-10-2018 C2I25_03815 59151f88828dea9b63716ca87c250a32 361 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 359 64.004 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 C2I25_03815 59151f88828dea9b63716ca87c250a32 361 PIRSF PIRSF001455 3 360 1.2E-100 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 C2I25_03815 59151f88828dea9b63716ca87c250a32 361 Pfam PF01761 3-dehydroquinate synthase 68 323 1.1E-95 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 C2I25_25020 80c21224d2b57af31269913adf640635 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 1.7E-22 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_25020 80c21224d2b57af31269913adf640635 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 1.1E-18 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_09715 c028b02902dc410fd31995b4c600b3f1 360 Pfam PF01522 Polysaccharide deacetylase 195 316 9.7E-17 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_09715 c028b02902dc410fd31995b4c600b3f1 360 Gene3D G3DSA:2.60.40.3760 45 141 1.1E-43 T 14-10-2018 C2I25_09715 c028b02902dc410fd31995b4c600b3f1 360 Gene3D G3DSA:3.20.20.370 142 360 1.2E-64 T 14-10-2018 C2I25_09715 c028b02902dc410fd31995b4c600b3f1 360 SUPERFAMILY SSF88713 162 332 7.51E-27 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_18320 58f996f7f3b834b01d1ddb671160914a 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 142 4.0E-65 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I25_18320 58f996f7f3b834b01d1ddb671160914a 146 Gene3D G3DSA:3.40.50.9100 1 146 4.2E-65 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I25_18320 58f996f7f3b834b01d1ddb671160914a 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 65.985 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I25_18320 58f996f7f3b834b01d1ddb671160914a 146 Pfam PF01220 Dehydroquinase class II 3 139 1.8E-61 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I25_18320 58f996f7f3b834b01d1ddb671160914a 146 PIRSF PIRSF001399 1 146 8.0E-63 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I25_18320 58f996f7f3b834b01d1ddb671160914a 146 SUPERFAMILY SSF52304 3 144 7.72E-59 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I25_18320 58f996f7f3b834b01d1ddb671160914a 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I25_18320 58f996f7f3b834b01d1ddb671160914a 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 141 2.0E-65 T 14-10-2018 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 2.4E-38 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 2.4E-38 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 2.4E-38 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 2.4E-38 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 2.4E-38 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 Gene3D G3DSA:3.90.226.10 28 282 1.3E-88 T 14-10-2018 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 16 280 1.5E-129 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 281 38.962 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 SUPERFAMILY SSF52096 29 281 3.65E-84 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_16290 cc78c252364dd661c658930ed3ef1d9e 289 Pfam PF01039 Carboxyl transferase domain 62 242 5.6E-21 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 C2I25_28115 73bc98a5cea2f7c6fbe42a5fcf30eca0 174 SUPERFAMILY SSF109854 7 165 1.3E-29 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_28115 73bc98a5cea2f7c6fbe42a5fcf30eca0 174 Pfam PF05163 DinB family 5 170 8.6E-32 T 14-10-2018 IPR007837 DNA damage-inducible protein DinB C2I25_28115 73bc98a5cea2f7c6fbe42a5fcf30eca0 174 Gene3D G3DSA:1.20.120.450 1 170 1.9E-41 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_26840 6b0ab6a9926e179d092f85a417c5bdea 235 SMART SM00448 2 112 1.8E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_26840 6b0ab6a9926e179d092f85a417c5bdea 235 Gene3D G3DSA:3.40.50.2300 2 123 5.4E-28 T 14-10-2018 C2I25_26840 6b0ab6a9926e179d092f85a417c5bdea 235 Gene3D G3DSA:1.10.10.10 124 227 1.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_26840 6b0ab6a9926e179d092f85a417c5bdea 235 SMART SM00862 150 225 1.5E-16 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_26840 6b0ab6a9926e179d092f85a417c5bdea 235 Pfam PF00072 Response regulator receiver domain 4 112 5.5E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_26840 6b0ab6a9926e179d092f85a417c5bdea 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 2.7E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_26840 6b0ab6a9926e179d092f85a417c5bdea 235 SUPERFAMILY SSF46894 128 226 3.12E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_26840 6b0ab6a9926e179d092f85a417c5bdea 235 SUPERFAMILY SSF52172 3 118 7.26E-33 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_04835 b34bf2831a8f5407ae95ffd77d05bd36 361 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 9 359 8.3E-137 T 14-10-2018 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 C2I25_04835 b34bf2831a8f5407ae95ffd77d05bd36 361 Pfam PF00561 alpha/beta hydrolase fold 71 338 2.8E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_04835 b34bf2831a8f5407ae95ffd77d05bd36 361 Gene3D G3DSA:3.40.50.1820 262 360 8.6E-7 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_04835 b34bf2831a8f5407ae95ffd77d05bd36 361 Gene3D G3DSA:3.40.50.1820 52 243 3.5E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_04835 b34bf2831a8f5407ae95ffd77d05bd36 361 SUPERFAMILY SSF53474 56 357 7.29E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_20290 e8b4fd42a7bab738b66bda14ed8e2e08 90 SUPERFAMILY SSF54565 2 86 2.62E-35 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20290 e8b4fd42a7bab738b66bda14ed8e2e08 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 14-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20290 e8b4fd42a7bab738b66bda14ed8e2e08 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.0E-35 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20290 e8b4fd42a7bab738b66bda14ed8e2e08 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.217 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20290 e8b4fd42a7bab738b66bda14ed8e2e08 90 Pfam PF00886 Ribosomal protein S16 9 67 1.2E-26 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20290 e8b4fd42a7bab738b66bda14ed8e2e08 90 Gene3D G3DSA:3.30.1320.10 1 90 1.4E-37 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_04190 bf73ba21abf9d34b9bdfe71f7a916bd1 258 SUPERFAMILY SSF53335 4 195 4.71E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_04190 bf73ba21abf9d34b9bdfe71f7a916bd1 258 Gene3D G3DSA:3.40.50.150 3 257 4.0E-40 T 14-10-2018 C2I25_04190 bf73ba21abf9d34b9bdfe71f7a916bd1 258 Pfam PF08241 Methyltransferase domain 40 134 8.1E-27 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_09745 c8ccbe4bc6f9be218376a78a7ceda8cc 479 SUPERFAMILY SSF53383 59 468 8.76E-138 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_09745 c8ccbe4bc6f9be218376a78a7ceda8cc 479 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 49 468 2.0E-198 T 14-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 C2I25_09745 c8ccbe4bc6f9be218376a78a7ceda8cc 479 PIRSF PIRSF000521 8 169 7.4E-11 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_09745 c8ccbe4bc6f9be218376a78a7ceda8cc 479 PIRSF PIRSF000521 162 470 1.1E-40 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_09745 c8ccbe4bc6f9be218376a78a7ceda8cc 479 Gene3D G3DSA:3.90.1150.10 45 463 2.2E-168 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_09745 c8ccbe4bc6f9be218376a78a7ceda8cc 479 Gene3D G3DSA:3.40.640.10 98 365 2.2E-168 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_09745 c8ccbe4bc6f9be218376a78a7ceda8cc 479 Pfam PF00202 Aminotransferase class-III 62 465 3.5E-134 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_09745 c8ccbe4bc6f9be218376a78a7ceda8cc 479 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 282 319 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_14185 21ae25bd201e55049ae3cfc929cbf3d9 261 SMART SM00382 30 225 2.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_14185 21ae25bd201e55049ae3cfc929cbf3d9 261 Pfam PF00005 ABC transporter 21 173 8.9E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_14185 21ae25bd201e55049ae3cfc929cbf3d9 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 2.2E-113 T 14-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 C2I25_14185 21ae25bd201e55049ae3cfc929cbf3d9 261 SUPERFAMILY SSF52540 6 233 5.45E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_14185 21ae25bd201e55049ae3cfc929cbf3d9 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_14185 21ae25bd201e55049ae3cfc929cbf3d9 261 Gene3D G3DSA:3.40.50.300 4 253 2.5E-55 T 14-10-2018 C2I25_23460 1481ed10f80c89330e6eb2ab85abbd27 360 Pfam PF00266 Aminotransferase class-V 4 348 7.5E-53 T 14-10-2018 IPR000192 Aminotransferase class V domain C2I25_23460 1481ed10f80c89330e6eb2ab85abbd27 360 Gene3D G3DSA:3.40.640.10 17 256 3.5E-91 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_23460 1481ed10f80c89330e6eb2ab85abbd27 360 PIRSF PIRSF000525 1 360 3.5E-156 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 C2I25_23460 1481ed10f80c89330e6eb2ab85abbd27 360 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 357 1.4E-160 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 C2I25_23460 1481ed10f80c89330e6eb2ab85abbd27 360 SUPERFAMILY SSF53383 1 356 8.54E-115 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_23460 1481ed10f80c89330e6eb2ab85abbd27 360 Gene3D G3DSA:3.90.1150.10 257 359 4.6E-40 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_23460 1481ed10f80c89330e6eb2ab85abbd27 360 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 206 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site C2I25_23460 1481ed10f80c89330e6eb2ab85abbd27 360 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 359 50.984 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 C2I25_10480 a8de9235ddca643372eb39003cefdf28 317 Pfam PF00892 EamA-like transporter family 3 141 1.1E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_10480 a8de9235ddca643372eb39003cefdf28 317 Pfam PF00892 EamA-like transporter family 157 291 9.2E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_15375 c863d5b10a57c5708f1fb66b93d2723f 306 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 54 293 2.4E-33 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 C2I25_15375 c863d5b10a57c5708f1fb66b93d2723f 306 Gene3D G3DSA:3.40.1390.30 53 283 1.8E-27 T 14-10-2018 C2I25_15375 c863d5b10a57c5708f1fb66b93d2723f 306 Gene3D G3DSA:3.40.1390.30 134 275 1.8E-27 T 14-10-2018 C2I25_15375 c863d5b10a57c5708f1fb66b93d2723f 306 SUPERFAMILY SSF102705 53 303 2.75E-42 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily C2I25_15215 9d59defc0ed22597f034bbe83860d514 187 SMART SM00947 26 182 1.0E-40 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 C2I25_15215 9d59defc0ed22597f034bbe83860d514 187 Gene3D G3DSA:3.40.1050.10 2 183 1.2E-47 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 C2I25_15215 9d59defc0ed22597f034bbe83860d514 187 Pfam PF00484 Carbonic anhydrase 33 178 2.3E-20 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 C2I25_15215 9d59defc0ed22597f034bbe83860d514 187 SUPERFAMILY SSF53056 1 181 1.96E-43 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 C2I25_22480 a638166269b48277b1cb6f03907bc80e 345 Pfam PF00144 Beta-lactamase 8 327 8.6E-42 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_22480 a638166269b48277b1cb6f03907bc80e 345 SUPERFAMILY SSF56601 7 326 1.23E-63 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_22480 a638166269b48277b1cb6f03907bc80e 345 Gene3D G3DSA:3.40.710.10 5 334 1.5E-59 T 14-10-2018 C2I25_02405 93697ebdeb24c08cf5c0053a7e26b7d7 557 SUPERFAMILY SSF143975 1 373 7.59E-140 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I25_02405 93697ebdeb24c08cf5c0053a7e26b7d7 557 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 460 471 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I25_02405 93697ebdeb24c08cf5c0053a7e26b7d7 557 Pfam PF00920 Dehydratase family 31 549 4.5E-227 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I25_02405 93697ebdeb24c08cf5c0053a7e26b7d7 557 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I25_02405 93697ebdeb24c08cf5c0053a7e26b7d7 557 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 552 5.1E-253 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I25_02405 93697ebdeb24c08cf5c0053a7e26b7d7 557 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 552 47.236 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I25_02405 93697ebdeb24c08cf5c0053a7e26b7d7 557 SUPERFAMILY SSF52016 374 552 2.9E-60 T 14-10-2018 C2I25_02405 93697ebdeb24c08cf5c0053a7e26b7d7 557 Gene3D G3DSA:3.50.30.80 374 523 1.2E-52 T 14-10-2018 C2I25_17060 5fcd4015d330b583100b802295c75fb3 114 SUPERFAMILY SSF118010 1 110 1.7E-30 T 14-10-2018 IPR036764 Cysteine protease Prp superfamily C2I25_17060 5fcd4015d330b583100b802295c75fb3 114 Pfam PF04327 Cysteine protease Prp 1 105 3.4E-25 T 14-10-2018 IPR007422 Cysteine protease Prp C2I25_17060 5fcd4015d330b583100b802295c75fb3 114 Gene3D G3DSA:3.30.70.1490 1 112 2.6E-33 T 14-10-2018 IPR036764 Cysteine protease Prp superfamily C2I25_02715 868a675429aac3299718b43bf0650b89 184 ProSitePatterns PS00194 Thioredoxin family active site. 74 92 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 C2I25_02715 868a675429aac3299718b43bf0650b89 184 Gene3D G3DSA:3.40.30.10 17 184 6.6E-44 T 14-10-2018 C2I25_02715 868a675429aac3299718b43bf0650b89 184 Pfam PF00578 AhpC/TSA family 46 162 3.7E-26 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I25_02715 868a675429aac3299718b43bf0650b89 184 SUPERFAMILY SSF52833 43 183 4.73E-43 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_23290 9573ac10a3f8b9e8f331dd4c1a0fa02b 240 Pfam PF14256 YwiC-like protein 5 130 1.1E-41 T 14-10-2018 IPR025576 YwiC-like protein C2I25_23965 602e7ce9b5a992e9e034855c1516a54c 153 Gene3D G3DSA:1.20.1260.100 3 153 7.3E-29 T 14-10-2018 IPR038330 TspO/MBR-related superfamily C2I25_23965 602e7ce9b5a992e9e034855c1516a54c 153 PIRSF PIRSF005859 1 153 1.1E-39 T 14-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 C2I25_23965 602e7ce9b5a992e9e034855c1516a54c 153 Pfam PF03073 TspO/MBR family 11 150 8.8E-29 T 14-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 C2I25_01970 a7d2d6d03f0b1d4558aa516822b62701 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 6.4E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal C2I25_01970 a7d2d6d03f0b1d4558aa516822b62701 257 SUPERFAMILY SSF52540 3 246 1.44E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01970 a7d2d6d03f0b1d4558aa516822b62701 257 SMART SM00382 29 225 2.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_01970 a7d2d6d03f0b1d4558aa516822b62701 257 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_01970 a7d2d6d03f0b1d4558aa516822b62701 257 Pfam PF00005 ABC transporter 21 176 5.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_01970 a7d2d6d03f0b1d4558aa516822b62701 257 Gene3D G3DSA:3.40.50.300 2 249 4.1E-59 T 14-10-2018 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 Gene3D G3DSA:2.30.30.30 1 62 1.5E-31 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 SMART SM00841 129 184 3.2E-34 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 SUPERFAMILY SSF50249 128 185 3.22E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 Gene3D G3DSA:2.40.50.140 128 185 2.6E-27 T 14-10-2018 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 Gene3D G3DSA:2.40.50.140 64 127 1.8E-27 T 14-10-2018 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 1.6E-22 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.0E-82 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.9E-26 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 SUPERFAMILY SSF50249 65 129 5.14E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.128 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 SUPERFAMILY SSF50104 1 63 4.21E-22 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 SMART SM01185 67 121 3.7E-25 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 14-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 4.3E-28 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like C2I25_18330 443e3829c5aa1dd77163ca39b2d0c45d 185 PIRSF PIRSF005901 1 185 1.5E-72 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP C2I25_24575 b42a2e439069104c8e7df42dfcd9933e 795 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 183 492 4.7E-88 T 14-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I25_24575 b42a2e439069104c8e7df42dfcd9933e 795 Pfam PF05547 Immune inhibitor A peptidase M6 148 791 7.4E-299 T 14-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I25_24575 b42a2e439069104c8e7df42dfcd9933e 795 SUPERFAMILY SSF55486 262 429 8.1E-17 T 14-10-2018 C2I25_24575 b42a2e439069104c8e7df42dfcd9933e 795 PIRSF PIRSF007519 1 795 0.0 T 14-10-2018 IPR012300 Peptidase M6, InhA C2I25_23535 664e9c7aa298829a4964e4f94608c794 207 Gene3D G3DSA:1.10.10.10 5 84 2.6E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23535 664e9c7aa298829a4964e4f94608c794 207 SMART SM00418 11 126 0.0017 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_23535 664e9c7aa298829a4964e4f94608c794 207 SUPERFAMILY SSF46785 3 157 1.14E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23535 664e9c7aa298829a4964e4f94608c794 207 Pfam PF12840 Helix-turn-helix domain 12 65 3.4E-8 T 14-10-2018 C2I25_04440 97e7ed358817a6b97c2d705d9aad3a30 82 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 4 50 3.0E-20 T 14-10-2018 IPR005370 Uncharacterised protein family UPF0180 C2I25_04440 97e7ed358817a6b97c2d705d9aad3a30 82 Pfam PF03698 Uncharacterised protein family (UPF0180) 6 81 3.1E-30 T 14-10-2018 IPR005370 Uncharacterised protein family UPF0180 C2I25_04440 97e7ed358817a6b97c2d705d9aad3a30 82 Hamap MF_00506 UPF0180 protein . 4 82 29.096 T 14-10-2018 IPR005370 Uncharacterised protein family UPF0180 C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 SMART SM00387 295 402 1.0E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 3.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 399 3.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 361 3.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 347 3.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 Gene3D G3DSA:1.10.287.130 194 249 6.5E-10 T 14-10-2018 C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 SUPERFAMILY SSF55874 254 400 1.7E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 296 400 9.4E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 SUPERFAMILY SSF47384 182 248 1.47E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 Gene3D G3DSA:3.30.565.10 255 410 5.2E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 SMART SM00388 191 253 0.0029 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_15340 5dda20ab1f9168aaeb8ab989b8c4804d 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 193 248 1.6E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_18915 77f57f2bcad8e0d34172409fd044aba1 81 ProDom PD058987 CYTOSOLIC YQKC 21 81 9.0E-30 T 14-10-2018 IPR020157 Uncharacterised protein family YqkC C2I25_18915 77f57f2bcad8e0d34172409fd044aba1 81 Pfam PF10827 Protein of unknown function (DUF2552) 1 79 2.3E-44 T 14-10-2018 IPR020157 Uncharacterised protein family YqkC C2I25_19260 a127e2802c2457bcfda93b34782c36fa 292 Gene3D G3DSA:3.40.50.720 1 166 8.3E-52 T 14-10-2018 C2I25_19260 a127e2802c2457bcfda93b34782c36fa 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 163 2.4E-54 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I25_19260 a127e2802c2457bcfda93b34782c36fa 292 PIRSF PIRSF000103 1 291 2.6E-71 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 C2I25_19260 a127e2802c2457bcfda93b34782c36fa 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 169 285 8.8E-36 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 C2I25_19260 a127e2802c2457bcfda93b34782c36fa 292 SUPERFAMILY SSF48179 167 289 1.47E-39 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_19260 a127e2802c2457bcfda93b34782c36fa 292 Gene3D G3DSA:1.10.1040.10 167 291 6.1E-41 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_19260 a127e2802c2457bcfda93b34782c36fa 292 SUPERFAMILY SSF51735 6 167 6.11E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_26435 524345d80a9bd6f5a7f3add7e8867b0d 283 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 251 1.2E-26 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_26435 524345d80a9bd6f5a7f3add7e8867b0d 283 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 278 4.5E-77 T 14-10-2018 C2I25_26435 524345d80a9bd6f5a7f3add7e8867b0d 283 SUPERFAMILY SSF56784 2 282 5.66E-68 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_26435 524345d80a9bd6f5a7f3add7e8867b0d 283 Gene3D G3DSA:3.40.50.1000 2 275 4.6E-84 T 14-10-2018 IPR023214 HAD superfamily C2I25_26435 524345d80a9bd6f5a7f3add7e8867b0d 283 Gene3D G3DSA:3.30.1240.10 80 207 4.6E-84 T 14-10-2018 C2I25_26435 524345d80a9bd6f5a7f3add7e8867b0d 283 ProSitePatterns PS01229 Hypothetical cof family signature 2. 232 254 - T 14-10-2018 C2I25_26435 524345d80a9bd6f5a7f3add7e8867b0d 283 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 278 8.6E-57 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_26435 524345d80a9bd6f5a7f3add7e8867b0d 283 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 14-10-2018 C2I25_13305 f9ec63a193ac0222e9f80ec6f5e3a4e7 107 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 36 103 6.5E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_13305 f9ec63a193ac0222e9f80ec6f5e3a4e7 107 SUPERFAMILY SSF46626 8 105 1.86E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I25_13305 f9ec63a193ac0222e9f80ec6f5e3a4e7 107 Gene3D G3DSA:1.10.760.10 38 107 7.0E-25 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I25_13305 f9ec63a193ac0222e9f80ec6f5e3a4e7 107 PIRSF PIRSF000025 1 107 1.0E-34 T 14-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 C2I25_18970 1e02506b28c541acf49b8616be85abfb 304 SUPERFAMILY SSF51430 1 298 1.57E-79 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_18970 1e02506b28c541acf49b8616be85abfb 304 Gene3D G3DSA:3.20.20.100 1 296 5.6E-108 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_18970 1e02506b28c541acf49b8616be85abfb 304 Pfam PF00248 Aldo/keto reductase family 15 295 2.9E-66 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_18970 1e02506b28c541acf49b8616be85abfb 304 PRINTS PR00069 Aldo-keto reductase signature 37 61 8.1E-7 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_18970 1e02506b28c541acf49b8616be85abfb 304 PRINTS PR00069 Aldo-keto reductase signature 103 121 8.1E-7 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_18970 1e02506b28c541acf49b8616be85abfb 304 PRINTS PR00069 Aldo-keto reductase signature 134 151 8.1E-7 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.7E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 Pfam PF03466 LysR substrate binding domain 91 286 2.0E-29 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 SUPERFAMILY SSF53850 93 286 2.61E-28 T 14-10-2018 C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.3E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 Gene3D G3DSA:3.40.190.290 91 291 7.3E-30 T 14-10-2018 C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 Gene3D G3DSA:1.10.10.10 1 90 2.2E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24035 f6afb8a61edec19ac292bb8e9bb0bdd9 292 SUPERFAMILY SSF46785 1 85 5.44E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_10535 7931df6f83badb25bddfeaab9fe5be98 546 Gene3D G3DSA:3.90.76.10 74 195 1.5E-173 T 14-10-2018 C2I25_10535 7931df6f83badb25bddfeaab9fe5be98 546 SUPERFAMILY SSF53850 36 531 1.45E-120 T 14-10-2018 C2I25_10535 7931df6f83badb25bddfeaab9fe5be98 546 Gene3D G3DSA:3.10.105.10 295 517 1.5E-173 T 14-10-2018 C2I25_10535 7931df6f83badb25bddfeaab9fe5be98 546 Gene3D G3DSA:3.40.190.10 55 530 1.5E-173 T 14-10-2018 C2I25_10535 7931df6f83badb25bddfeaab9fe5be98 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 463 3.2E-74 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_10535 7931df6f83badb25bddfeaab9fe5be98 546 PIRSF PIRSF002741 2 546 2.2E-104 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_21420 5d9464402ab89146e5bd8d09745ea7cf 191 Pfam PF02632 BioY family 29 171 7.0E-36 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I25_21420 5d9464402ab89146e5bd8d09745ea7cf 191 Gene3D G3DSA:1.10.1760.20 1 178 2.7E-50 T 14-10-2018 C2I25_21420 5d9464402ab89146e5bd8d09745ea7cf 191 PIRSF PIRSF016661 1 179 1.7E-48 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I25_27850 11eb2e3560a7d2036e7b9d42276eff0b 198 SUPERFAMILY SSF49899 35 197 4.35E-29 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I25_27850 11eb2e3560a7d2036e7b9d42276eff0b 198 PIRSF PIRSF022704 2 198 3.2E-71 T 14-10-2018 IPR015987 Uncharacterised conserved protein UCP022704 C2I25_27850 11eb2e3560a7d2036e7b9d42276eff0b 198 Pfam PF07081 Protein of unknown function (DUF1349) 16 197 2.0E-54 T 14-10-2018 IPR009784 Protein of unknown function DUF1349 C2I25_27850 11eb2e3560a7d2036e7b9d42276eff0b 198 Gene3D G3DSA:2.60.120.200 9 198 5.0E-47 T 14-10-2018 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 Pfam PF03705 CheR methyltransferase, all-alpha domain 21 70 7.8E-12 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 SUPERFAMILY SSF47757 15 87 1.16E-8 T 14-10-2018 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 PRINTS PR00996 Glutamate methyltransferase family signature 78 90 1.8E-26 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 PRINTS PR00996 Glutamate methyltransferase family signature 146 162 1.8E-26 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 PRINTS PR00996 Glutamate methyltransferase family signature 220 234 1.8E-26 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 PRINTS PR00996 Glutamate methyltransferase family signature 41 54 1.8E-26 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 PRINTS PR00996 Glutamate methyltransferase family signature 114 134 1.8E-26 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 PRINTS PR00996 Glutamate methyltransferase family signature 239 262 1.8E-26 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 Pfam PF01739 CheR methyltransferase, SAM binding domain 85 263 1.4E-41 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 SMART SM00138 19 282 8.9E-41 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 SUPERFAMILY SSF53335 85 266 1.59E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_06415 653d668b145f21d3dc304a1d119401ca 285 Gene3D G3DSA:3.40.50.150 84 284 1.6E-58 T 14-10-2018 C2I25_13250 b8bb7ccdfda04a0ce48722a1af683e32 280 Gene3D G3DSA:3.40.50.10170 1 151 1.4E-53 T 14-10-2018 C2I25_13250 b8bb7ccdfda04a0ce48722a1af683e32 280 SUPERFAMILY SSF82549 1 280 8.37E-97 T 14-10-2018 C2I25_13250 b8bb7ccdfda04a0ce48722a1af683e32 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 3.8E-106 T 14-10-2018 IPR003797 DegV C2I25_13250 b8bb7ccdfda04a0ce48722a1af683e32 280 Gene3D G3DSA:3.30.1180.10 152 280 2.7E-46 T 14-10-2018 C2I25_13250 b8bb7ccdfda04a0ce48722a1af683e32 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 3.1E-99 T 14-10-2018 IPR003797 DegV C2I25_02650 6e2df16a82268079c435182577e248c2 366 SUPERFAMILY SSF55874 262 366 9.61E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_02650 6e2df16a82268079c435182577e248c2 366 Gene3D G3DSA:3.30.565.10 250 365 1.9E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_02650 6e2df16a82268079c435182577e248c2 366 Pfam PF07730 Histidine kinase 177 243 7.8E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I25_06590 5c00530a05ea68314ee224527058d5eb 152 Pfam PF12802 MarR family 32 90 1.2E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_06590 5c00530a05ea68314ee224527058d5eb 152 Gene3D G3DSA:1.10.10.10 2 144 5.0E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_06590 5c00530a05ea68314ee224527058d5eb 152 SUPERFAMILY SSF46785 4 139 6.65E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_06590 5c00530a05ea68314ee224527058d5eb 152 SMART SM00347 26 126 2.8E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_26225 824f34832d4dc5db5a5a51fdc122fb2f 281 Pfam PF08239 Bacterial SH3 domain 155 199 5.6E-7 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_26225 824f34832d4dc5db5a5a51fdc122fb2f 281 Gene3D G3DSA:2.30.30.40 152 210 5.5E-9 T 14-10-2018 C2I25_26225 824f34832d4dc5db5a5a51fdc122fb2f 281 Gene3D G3DSA:2.30.30.40 224 279 1.9E-10 T 14-10-2018 C2I25_26225 824f34832d4dc5db5a5a51fdc122fb2f 281 SUPERFAMILY SSF55166 9 120 7.06E-23 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_26225 824f34832d4dc5db5a5a51fdc122fb2f 281 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 56 120 5.3E-17 T 14-10-2018 IPR039561 Peptidase M15C GO:0008233 C2I25_26225 824f34832d4dc5db5a5a51fdc122fb2f 281 SMART SM00287 220 281 0.04 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_26225 824f34832d4dc5db5a5a51fdc122fb2f 281 SMART SM00287 147 201 0.1 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_26225 824f34832d4dc5db5a5a51fdc122fb2f 281 Gene3D G3DSA:3.30.1380.10 1 119 1.1E-23 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_05585 18d932db9170d81a6fc04d767cb88b6f 285 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 226 280 2.1E-19 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_05585 18d932db9170d81a6fc04d767cb88b6f 285 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 14 220 6.0E-58 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_05585 18d932db9170d81a6fc04d767cb88b6f 285 PIRSF PIRSF006483 1 285 1.2E-93 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_05585 18d932db9170d81a6fc04d767cb88b6f 285 Gene3D G3DSA:3.30.70.120 198 272 1.9E-19 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_12405 a965aeab74e97ca09902bd014a593707 200 SUPERFAMILY SSF52172 1 128 2.28E-30 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_12405 a965aeab74e97ca09902bd014a593707 200 Gene3D G3DSA:3.40.50.12740 2 200 3.5E-58 T 14-10-2018 C2I25_12405 a965aeab74e97ca09902bd014a593707 200 SUPERFAMILY SSF46894 129 199 7.14E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_12405 a965aeab74e97ca09902bd014a593707 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 3.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12405 a965aeab74e97ca09902bd014a593707 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 3.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12405 a965aeab74e97ca09902bd014a593707 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 3.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12405 a965aeab74e97ca09902bd014a593707 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 4.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12405 a965aeab74e97ca09902bd014a593707 200 SMART SM00421 137 194 2.5E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12405 a965aeab74e97ca09902bd014a593707 200 Pfam PF00072 Response regulator receiver domain 4 116 3.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12405 a965aeab74e97ca09902bd014a593707 200 SMART SM00448 2 115 4.3E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_17715 587d3d8957af6dcee98bced51a76b5b0 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 5.0E-96 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 C2I25_17715 587d3d8957af6dcee98bced51a76b5b0 312 PIRSF PIRSF000401 1 312 1.5E-119 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 C2I25_17715 587d3d8957af6dcee98bced51a76b5b0 312 SUPERFAMILY SSF53335 66 309 5.53E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_17715 587d3d8957af6dcee98bced51a76b5b0 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 310 5.3E-106 T 14-10-2018 C2I25_17715 587d3d8957af6dcee98bced51a76b5b0 312 Gene3D G3DSA:3.40.50.150 116 311 2.0E-62 T 14-10-2018 C2I25_17715 587d3d8957af6dcee98bced51a76b5b0 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 37.164 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 C2I25_21360 a5745ab3cb56f24cd6e4f4b26df5604f 627 ProSitePatterns PS00211 ABC transporters family signature. 515 529 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_21360 a5745ab3cb56f24cd6e4f4b26df5604f 627 Gene3D G3DSA:1.20.1560.10 29 348 3.4E-17 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_21360 a5745ab3cb56f24cd6e4f4b26df5604f 627 SMART SM00382 398 595 5.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_21360 a5745ab3cb56f24cd6e4f4b26df5604f 627 SUPERFAMILY SSF90123 29 331 6.02E-28 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_21360 a5745ab3cb56f24cd6e4f4b26df5604f 627 SUPERFAMILY SSF52540 368 613 4.33E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21360 a5745ab3cb56f24cd6e4f4b26df5604f 627 Gene3D G3DSA:3.40.50.300 366 623 1.4E-74 T 14-10-2018 C2I25_21360 a5745ab3cb56f24cd6e4f4b26df5604f 627 Pfam PF00005 ABC transporter 389 543 1.3E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 Gene3D G3DSA:1.20.120.1810 26 131 2.2E-25 T 14-10-2018 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 Pfam PF04542 Sigma-70 region 2 62 131 2.1E-18 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 PIRSF PIRSF000770 2 239 3.9E-79 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 3.9E-35 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 SUPERFAMILY SSF88946 24 130 4.97E-35 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 Gene3D G3DSA:1.10.10.10 168 239 4.2E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 Pfam PF04545 Sigma-70, region 4 180 233 1.8E-17 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 7 239 6.5E-138 T 14-10-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 7.1E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 7.1E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 7.1E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 7.1E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19975 09cdbafcc4851eefd0e17c8916c77fc5 239 SUPERFAMILY SSF88659 143 237 3.36E-22 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_01980 60940a9d7246cc2f2709c8f1e0cda742 307 Gene3D G3DSA:3.30.1220.10 200 303 1.3E-11 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily C2I25_01980 60940a9d7246cc2f2709c8f1e0cda742 307 SUPERFAMILY SSF90002 218 301 7.72E-15 T 14-10-2018 C2I25_01980 60940a9d7246cc2f2709c8f1e0cda742 307 SUPERFAMILY SSF52540 2 208 3.06E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01980 60940a9d7246cc2f2709c8f1e0cda742 307 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 218 301 1.2E-16 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I25_01980 60940a9d7246cc2f2709c8f1e0cda742 307 Gene3D G3DSA:3.40.50.300 1 199 3.1E-50 T 14-10-2018 C2I25_01980 60940a9d7246cc2f2709c8f1e0cda742 307 SMART SM00833 218 303 7.8E-20 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I25_01980 60940a9d7246cc2f2709c8f1e0cda742 307 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 184 1.5E-44 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 Gene3D G3DSA:3.40.50.620 1 222 1.6E-91 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 44.465 T 14-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 4.0E-29 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 4.0E-29 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 4.0E-29 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 4.0E-29 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 SUPERFAMILY SSF55174 321 417 3.93E-23 T 14-10-2018 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 SMART SM00363 352 410 0.0074 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 SUPERFAMILY SSF52374 1 323 7.41E-113 T 14-10-2018 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 417 3.3E-132 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 Gene3D G3DSA:1.10.240.10 223 325 1.6E-39 T 14-10-2018 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 Pfam PF01479 S4 domain 356 395 1.2E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 1.1E-83 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_13720 9f252879ff6ca5f39537a2b5218b1d14 420 Gene3D G3DSA:3.10.290.10 326 420 1.6E-31 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_21100 f04fe85afb6b9562757ae6daabe0af14 336 Pfam PF08378 Nuclease-related domain 149 276 6.1E-7 T 14-10-2018 IPR011528 Nuclease-related domain, NERD C2I25_12960 48bfc9fce09ac3ec92eb3dd768fe57d6 161 Pfam PF04892 VanZ like family 7 154 2.6E-23 T 14-10-2018 IPR006976 VanZ-like C2I25_12960 48bfc9fce09ac3ec92eb3dd768fe57d6 161 PIRSF PIRSF019083 1 161 1.7E-55 T 14-10-2018 IPR016747 Phosphotransbutyrylase C2I25_04710 3d94ac13810f1a1e0df020e3053def7d 220 PIRSF PIRSF006293 2 218 4.6E-78 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 C2I25_04710 3d94ac13810f1a1e0df020e3053def7d 220 Pfam PF06508 Queuosine biosynthesis protein QueC 5 211 4.0E-86 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 C2I25_04710 3d94ac13810f1a1e0df020e3053def7d 220 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 204 1.7E-84 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 C2I25_04710 3d94ac13810f1a1e0df020e3053def7d 220 Gene3D G3DSA:3.40.50.620 1 218 4.8E-75 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_04710 3d94ac13810f1a1e0df020e3053def7d 220 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 217 52.531 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 C2I25_04710 3d94ac13810f1a1e0df020e3053def7d 220 SUPERFAMILY SSF52402 3 211 6.4E-70 T 14-10-2018 C2I25_06075 a465b7f566aec7409c175cd8f2f88075 313 SUPERFAMILY SSF103481 192 292 2.48E-12 T 14-10-2018 C2I25_06075 a465b7f566aec7409c175cd8f2f88075 313 Pfam PF00892 EamA-like transporter family 158 289 3.4E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_06075 a465b7f566aec7409c175cd8f2f88075 313 Pfam PF00892 EamA-like transporter family 14 143 3.1E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_06075 a465b7f566aec7409c175cd8f2f88075 313 SUPERFAMILY SSF103481 45 145 1.57E-14 T 14-10-2018 C2I25_09985 abf283f5f12ff6578e82bc3809930eea 643 SUPERFAMILY SSF53448 368 612 6.19E-40 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09985 abf283f5f12ff6578e82bc3809930eea 643 Gene3D G3DSA:3.40.50.2000 111 166 7.9E-24 T 14-10-2018 C2I25_09985 abf283f5f12ff6578e82bc3809930eea 643 Gene3D G3DSA:3.90.550.10 323 639 9.4E-43 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09985 abf283f5f12ff6578e82bc3809930eea 643 Pfam PF00534 Glycosyl transferases group 1 180 335 1.3E-14 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 C2I25_09985 abf283f5f12ff6578e82bc3809930eea 643 SUPERFAMILY SSF53756 7 363 3.14E-43 T 14-10-2018 C2I25_09985 abf283f5f12ff6578e82bc3809930eea 643 Gene3D G3DSA:3.40.50.2000 167 313 7.9E-24 T 14-10-2018 C2I25_09985 abf283f5f12ff6578e82bc3809930eea 643 Pfam PF00535 Glycosyl transferase family 2 370 481 2.8E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_09520 ce83dbbfc44dc33d84ca1affea5df5fc 361 Pfam PF00487 Fatty acid desaturase 54 299 1.4E-37 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 C2I25_03960 0f9f525c3db8d2da06ff53b3afda7212 292 SUPERFAMILY SSF46955 9 82 1.37E-15 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_03960 0f9f525c3db8d2da06ff53b3afda7212 292 Pfam PF13411 MerR HTH family regulatory protein 9 77 2.0E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_03960 0f9f525c3db8d2da06ff53b3afda7212 292 SMART SM00422 9 78 2.3E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_03960 0f9f525c3db8d2da06ff53b3afda7212 292 Gene3D G3DSA:1.10.1660.10 4 77 2.5E-23 T 14-10-2018 C2I25_13005 74caccea9d37a8e83a3f9bf3c16eaf11 505 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 9 499 7.0E-191 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I25_13005 74caccea9d37a8e83a3f9bf3c16eaf11 505 ProSitePatterns PS01303 BCCT family of transporters signature. 315 324 - T 14-10-2018 IPR018093 BCCT transporter, conserved site C2I25_13005 74caccea9d37a8e83a3f9bf3c16eaf11 505 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 499 9.6E-161 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I25_16590 6ee3580a13c3d55d41decccf89f8a06b 291 Gene3D G3DSA:3.40.50.1980 33 120 5.2E-33 T 14-10-2018 C2I25_16590 6ee3580a13c3d55d41decccf89f8a06b 291 TIGRFAM TIGR03659 IsdE: heme ABC transporter, heme-binding protein isdE 2 290 3.8E-134 T 14-10-2018 IPR019957 ABC transporter, high-affinity heme uptake system protein IsdE GO:0015886|GO:0016020|GO:0020037 C2I25_16590 6ee3580a13c3d55d41decccf89f8a06b 291 Gene3D G3DSA:3.40.50.1980 121 291 3.1E-59 T 14-10-2018 C2I25_16590 6ee3580a13c3d55d41decccf89f8a06b 291 SUPERFAMILY SSF53807 36 291 7.46E-53 T 14-10-2018 C2I25_16590 6ee3580a13c3d55d41decccf89f8a06b 291 Pfam PF01497 Periplasmic binding protein 39 267 2.0E-40 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_12580 f184d1b1c0906bb0824067c673b9ac5c 146 SUPERFAMILY SSF52788 1 142 1.83E-42 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily C2I25_12580 f184d1b1c0906bb0824067c673b9ac5c 146 SMART SM00226 2 142 4.5E-40 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I25_12580 f184d1b1c0906bb0824067c673b9ac5c 146 Gene3D G3DSA:3.40.50.2300 2 145 4.3E-50 T 14-10-2018 C2I25_12580 f184d1b1c0906bb0824067c673b9ac5c 146 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 140 7.8E-34 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I25_12580 f184d1b1c0906bb0824067c673b9ac5c 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 41 57 6.4E-10 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I25_12580 f184d1b1c0906bb0824067c673b9ac5c 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 6.4E-10 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I25_12580 f184d1b1c0906bb0824067c673b9ac5c 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 114 129 6.4E-10 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I25_12580 f184d1b1c0906bb0824067c673b9ac5c 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 74 89 6.4E-10 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I25_26330 b9c77597f1aac5e4e8d6faeeb00f6576 293 Pfam PF00069 Protein kinase domain 76 244 1.6E-8 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_26330 b9c77597f1aac5e4e8d6faeeb00f6576 293 SUPERFAMILY SSF56112 71 286 6.39E-20 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_26330 b9c77597f1aac5e4e8d6faeeb00f6576 293 Gene3D G3DSA:1.10.510.10 75 291 2.1E-15 T 14-10-2018 C2I25_27115 ac7f320d3382e78c9820ae02c80c7061 262 Gene3D G3DSA:3.90.226.10 1 202 1.8E-73 T 14-10-2018 C2I25_27115 ac7f320d3382e78c9820ae02c80c7061 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I25_27115 ac7f320d3382e78c9820ae02c80c7061 262 SUPERFAMILY SSF52096 4 261 1.56E-84 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_27115 ac7f320d3382e78c9820ae02c80c7061 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 7.1E-71 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I25_27115 ac7f320d3382e78c9820ae02c80c7061 262 Gene3D G3DSA:1.10.12.10 203 262 1.0E-27 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I25_03865 9cb8d892f38ce2f0a8b5502a5365ed1d 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 1.7E-24 T 14-10-2018 IPR020076 Protein of unknown function DUF2768 C2I25_03865 9cb8d892f38ce2f0a8b5502a5365ed1d 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 1.0E-30 T 14-10-2018 IPR020076 Protein of unknown function DUF2768 C2I25_26915 2f9526ed82beaae35bbe67942845eea9 563 SUPERFAMILY SSF55486 32 558 2.08E-95 T 14-10-2018 C2I25_26915 2f9526ed82beaae35bbe67942845eea9 563 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 13 561 2.3E-242 T 14-10-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related C2I25_26915 2f9526ed82beaae35bbe67942845eea9 563 Pfam PF01432 Peptidase family M3 163 549 3.0E-44 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 C2I25_26915 2f9526ed82beaae35bbe67942845eea9 563 Gene3D G3DSA:1.10.1370.30 5 563 2.8E-153 T 14-10-2018 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Gene3D G3DSA:3.30.200.20 1 90 2.0E-33 T 14-10-2018 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 SUPERFAMILY SSF56112 7 269 3.91E-84 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 14-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Gene3D G3DSA:3.30.10.20 433 501 4.3E-9 T 14-10-2018 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Pfam PF03793 PASTA domain 438 499 6.7E-11 T 14-10-2018 IPR005543 PASTA domain C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Pfam PF03793 PASTA domain 369 431 3.1E-12 T 14-10-2018 IPR005543 PASTA domain C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Pfam PF03793 PASTA domain 508 565 1.7E-12 T 14-10-2018 IPR005543 PASTA domain C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 SMART SM00740 433 499 1.5E-5 T 14-10-2018 IPR005543 PASTA domain C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 SMART SM00740 365 432 3.2E-11 T 14-10-2018 IPR005543 PASTA domain C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 SMART SM00740 500 566 3.3E-12 T 14-10-2018 IPR005543 PASTA domain C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Pfam PF00069 Protein kinase domain 11 264 1.7E-54 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Gene3D G3DSA:2.60.40.2560 573 654 2.3E-15 T 14-10-2018 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Gene3D G3DSA:3.30.10.20 507 569 1.6E-14 T 14-10-2018 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Gene3D G3DSA:1.10.510.10 92 279 5.0E-53 T 14-10-2018 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 14-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 Gene3D G3DSA:3.30.10.20 366 432 1.1E-13 T 14-10-2018 C2I25_20195 f4e8620e751f0510b71d020d11022d06 657 SMART SM00220 11 271 5.9E-68 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 Hamap MF_01201 Alanine racemase. 7 374 34.281 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 TIGRFAM TIGR00492 alr: alanine racemase 8 374 2.5E-117 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 Gene3D G3DSA:3.20.20.10 16 229 1.1E-135 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 Pfam PF00842 Alanine racemase, C-terminal domain 249 372 5.1E-41 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 SUPERFAMILY SSF50621 244 385 1.46E-49 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 Gene3D G3DSA:2.40.37.10 11 373 1.1E-135 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 SMART SM01005 249 374 3.2E-67 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 33 49 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 69 87 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 356 369 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 207 234 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 164 175 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 282 297 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 265 280 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 129 141 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 302 319 2.3E-64 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 Pfam PF01168 Alanine racemase, N-terminal domain 14 234 3.3E-65 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_10265 2a78c3b305fdd74f8b7c425d7678695b 389 SUPERFAMILY SSF51419 14 250 7.2E-63 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 66 199 1.6E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 Gene3D G3DSA:1.10.150.240 16 100 2.1E-68 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 SUPERFAMILY SSF56784 2 226 1.22E-44 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 225 3.7E-65 T 14-10-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 198 1.2E-25 T 14-10-2018 C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 Gene3D G3DSA:3.40.50.1000 5 221 2.1E-68 T 14-10-2018 IPR023214 HAD superfamily C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 3.8E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 3.8E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 3.8E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 3.8E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_23135 69de4efc040e16d6292e62e7af33ea53 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 191 9.0E-17 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 Gene3D G3DSA:2.170.8.10 38 330 3.2E-227 T 14-10-2018 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 17 526 3.8E-249 T 14-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 528 56.333 T 14-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 Pfam PF01293 Phosphoenolpyruvate carboxykinase 20 481 4.2E-229 T 14-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 SUPERFAMILY SSF53795 213 524 2.52E-137 T 14-10-2018 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 Gene3D G3DSA:3.40.449.10 28 213 3.2E-227 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 SUPERFAMILY SSF68923 8 212 3.49E-81 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 PIRSF PIRSF006294 3 527 1.2E-246 T 14-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 250 265 - T 14-10-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I25_15405 89748338c240a4373633b16bd2010f7b 528 Gene3D G3DSA:3.90.228.20 214 513 3.2E-227 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 C2I25_21250 3eb67eb89f1c93a453f902dbe3d5a598 375 Gene3D G3DSA:3.20.20.70 21 373 6.4E-119 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_21250 3eb67eb89f1c93a453f902dbe3d5a598 375 SUPERFAMILY SSF51395 29 366 1.44E-111 T 14-10-2018 C2I25_21250 3eb67eb89f1c93a453f902dbe3d5a598 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 30 359 1.1E-89 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 C2I25_17230 2af948393385837709dae5b269c1eebf 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 167 1.0E-67 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 C2I25_17230 2af948393385837709dae5b269c1eebf 170 SUPERFAMILY SSF53271 3 163 3.12E-48 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_17230 2af948393385837709dae5b269c1eebf 170 Gene3D G3DSA:3.40.50.2020 1 169 8.4E-59 T 14-10-2018 C2I25_17230 2af948393385837709dae5b269c1eebf 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.436 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 C2I25_17230 2af948393385837709dae5b269c1eebf 170 Pfam PF00156 Phosphoribosyl transferase domain 31 148 7.8E-15 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 Gene3D G3DSA:3.30.565.10 273 424 1.3E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 6.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 6.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 6.5E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 SMART SM00387 314 421 2.8E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 419 8.7E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 270 8.9E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 SMART SM00388 209 273 3.8E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 SUPERFAMILY SSF55874 263 420 2.1E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 SUPERFAMILY SSF47384 200 271 5.49E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_19445 6f33dd0b3d2096dcbb2b998833504dd1 424 Gene3D G3DSA:1.10.287.130 212 270 2.1E-17 T 14-10-2018 C2I25_27530 3fd8140cdb0b15d2a7e6eac9ed3050bb 245 Pfam PF14171 Toxin SpoIISA, type II toxin-antitoxin system 10 243 7.6E-70 T 14-10-2018 IPR025940 Toxin SpoIISA, type II toxin-antitoxin system GO:0009405|GO:0016021 C2I25_27530 3fd8140cdb0b15d2a7e6eac9ed3050bb 245 ProDom PD120066 SPORULATION STAGE SA II SPOIISA TRANSMEMBRANE MEMBRANE KILLER 24 156 0.001 T 14-10-2018 C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.7E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.7E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.7E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.7E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.7E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 Pfam PF00106 short chain dehydrogenase 3 199 1.2E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 Gene3D G3DSA:3.40.50.720 1 233 7.6E-56 T 14-10-2018 C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 6.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 6.0E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02770 21be96ad2055e3885f283697693bf8b9 236 SUPERFAMILY SSF51735 3 236 4.41E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 SUPERFAMILY SSF50249 4 108 7.81E-32 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 SUPERFAMILY SSF55261 294 421 7.85E-44 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 559 2.3E-111 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 Gene3D G3DSA:2.40.50.140 1 110 4.5E-34 T 14-10-2018 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 Gene3D G3DSA:3.30.930.10 121 584 1.9E-195 T 14-10-2018 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 6.1E-27 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 6.1E-27 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 6.1E-27 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 6.1E-27 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 586 9.0E-261 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 1.3E-17 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 SUPERFAMILY SSF55681 113 585 5.77E-109 T 14-10-2018 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 586 34.82 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 Pfam PF02938 GAD domain 313 407 1.2E-31 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 C2I25_17255 5ed0e7c39c9f74bc8afa4863eb8e3e12 591 Gene3D G3DSA:3.30.1360.30 277 421 1.9E-195 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 321 340 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 Gene3D G3DSA:1.10.10.1330 81 206 1.6E-24 T 14-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 PIRSF PIRSF000774 1 434 8.5E-134 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 413 420 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 Pfam PF04552 Sigma-54, DNA binding domain 274 432 2.8E-62 T 14-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 Pfam PF04963 Sigma-54 factor, core binding domain 78 261 3.1E-54 T 14-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 Gene3D G3DSA:1.10.10.60 373 433 1.0E-23 T 14-10-2018 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 PRINTS PR00045 Sigma-54 factor signature 408 426 2.0E-26 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 PRINTS PR00045 Sigma-54 factor signature 147 164 2.0E-26 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 PRINTS PR00045 Sigma-54 factor signature 333 345 2.0E-26 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 PRINTS PR00045 Sigma-54 factor signature 349 360 2.0E-26 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 2.2E-13 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_13515 021bf6aff214084fb2fa6b30d8d21d24 435 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 432 6.6E-139 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 343 2.1E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 Gene3D G3DSA:3.30.565.10 208 366 3.4E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 SUPERFAMILY SSF55874 197 362 2.49E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 SMART SM00388 141 208 3.7E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 Gene3D G3DSA:1.10.287.130 137 207 1.6E-16 T 14-10-2018 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 SMART SM00304 81 133 2.7E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 362 8.3E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 206 2.4E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 SUPERFAMILY SSF47384 127 208 2.75E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 SMART SM00387 253 364 3.7E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 Gene3D G3DSA:1.20.1480.50 49 136 1.1E-5 T 14-10-2018 C2I25_14925 1e1e112de819b2c9439a86a4abdf2c37 368 SUPERFAMILY SSF158472 89 132 1.96E-5 T 14-10-2018 C2I25_05930 aeb2b2a92095fdbe8e6e5b60b40501b7 285 Gene3D G3DSA:1.10.3720.10 25 283 3.2E-65 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05930 aeb2b2a92095fdbe8e6e5b60b40501b7 285 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 19 280 8.4E-98 T 14-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 C2I25_05930 aeb2b2a92095fdbe8e6e5b60b40501b7 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 282 5.4E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_05930 aeb2b2a92095fdbe8e6e5b60b40501b7 285 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 26 282 7.5E-122 T 14-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 C2I25_05930 aeb2b2a92095fdbe8e6e5b60b40501b7 285 SUPERFAMILY SSF161098 23 277 1.57E-56 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_26315 7d8010d57fb29a3d0002e28dcd8ce2fb 199 Pfam PF01569 PAP2 superfamily 59 167 2.1E-18 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_26315 7d8010d57fb29a3d0002e28dcd8ce2fb 199 SMART SM00014 57 165 2.0E-14 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_26315 7d8010d57fb29a3d0002e28dcd8ce2fb 199 Gene3D G3DSA:1.20.144.10 1 180 1.9E-20 T 14-10-2018 C2I25_26315 7d8010d57fb29a3d0002e28dcd8ce2fb 199 SUPERFAMILY SSF48317 4 193 7.85E-38 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I25_07895 5f1929b50fea323fb88dc486f57e7395 174 Gene3D G3DSA:3.40.50.300 2 174 6.7E-24 T 14-10-2018 C2I25_07895 5f1929b50fea323fb88dc486f57e7395 174 SUPERFAMILY SSF52540 5 172 8.62E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07895 5f1929b50fea323fb88dc486f57e7395 174 Pfam PF13671 AAA domain 6 140 4.7E-13 T 14-10-2018 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 Pfam PF13365 Trypsin-like peptidase domain 104 251 2.7E-30 T 14-10-2018 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 Gene3D G3DSA:2.30.42.10 289 390 6.0E-21 T 14-10-2018 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 Pfam PF13180 PDZ domain 289 386 4.3E-15 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 SMART SM00228 289 377 1.3E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 SUPERFAMILY SSF50156 271 386 3.42E-20 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 SUPERFAMILY SSF50494 69 286 6.59E-56 T 14-10-2018 IPR009003 Peptidase S1, PA clan C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 Gene3D G3DSA:2.40.10.10 170 288 9.5E-38 T 14-10-2018 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 Gene3D G3DSA:2.40.10.10 58 169 3.5E-27 T 14-10-2018 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 PRINTS PR00834 HtrA/DegQ protease family signature 178 202 7.0E-36 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 PRINTS PR00834 HtrA/DegQ protease family signature 137 157 7.0E-36 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 7.0E-36 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 7.0E-36 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 PRINTS PR00834 HtrA/DegQ protease family signature 335 347 7.0E-36 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_11805 5f22202a1bcd241782e185c5d1ab7360 391 PRINTS PR00834 HtrA/DegQ protease family signature 116 128 7.0E-36 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_25675 1380dd7582974f614f73cc907ed3d9ce 145 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_25675 1380dd7582974f614f73cc907ed3d9ce 145 SUPERFAMILY SSF55811 5 125 2.03E-20 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_25675 1380dd7582974f614f73cc907ed3d9ce 145 PRINTS PR00502 NUDIX hydrolase family signature 31 45 9.5E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_25675 1380dd7582974f614f73cc907ed3d9ce 145 PRINTS PR00502 NUDIX hydrolase family signature 45 60 9.5E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_25675 1380dd7582974f614f73cc907ed3d9ce 145 Pfam PF00293 NUDIX domain 10 121 1.7E-10 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_25675 1380dd7582974f614f73cc907ed3d9ce 145 Gene3D G3DSA:3.90.79.10 2 141 4.4E-23 T 14-10-2018 C2I25_00045 c11dc027515d165cde43d4fe0466f123 606 Gene3D G3DSA:3.40.50.300 267 448 1.2E-15 T 14-10-2018 C2I25_00045 c11dc027515d165cde43d4fe0466f123 606 SUPERFAMILY SSF52540 280 447 5.4E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_00045 c11dc027515d165cde43d4fe0466f123 606 Pfam PF07728 AAA domain (dynein-related subfamily) 284 436 4.2E-7 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 C2I25_03295 e7b702a2e58fbc0528e32e4e66945e62 105 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 105 1.0E-53 T 14-10-2018 C2I25_03295 e7b702a2e58fbc0528e32e4e66945e62 105 Pfam PF09685 Domain of unknown function (DUF4870) 6 101 1.3E-6 T 14-10-2018 IPR019109 Protein of unknown function DUF4870 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Gene3D G3DSA:2.40.30.130 466 555 3.7E-10 T 14-10-2018 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 699 2.0E-16 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 SMART SM00863 656 699 8.1E-19 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Pfam PF01411 tRNA synthetases class II (A) 8 558 8.7E-212 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Gene3D G3DSA:3.10.310.40 768 877 1.6E-36 T 14-10-2018 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Gene3D G3DSA:3.30.980.10 565 700 6.2E-51 T 14-10-2018 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 SUPERFAMILY SSF50447 457 555 7.77E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Pfam PF02272 DHHA1 domain 736 875 3.0E-30 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 858 0.0 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Gene3D G3DSA:3.30.930.10 4 242 6.0E-94 T 14-10-2018 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 SUPERFAMILY SSF55681 5 245 1.86E-88 T 14-10-2018 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 SUPERFAMILY SSF101353 246 439 4.32E-68 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 184.536 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 Gene3D G3DSA:3.30.54.20 627 680 6.2E-51 T 14-10-2018 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 SUPERFAMILY SSF55186 555 720 5.23E-51 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 8.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 8.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 301 314 8.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 8.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I25_17335 6d93e60a7f82ef32d655cd82a175e107 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 277 293 8.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I25_28135 7a05cee70671c1236aca2a3a34442276 249 SUPERFAMILY SSF56214 18 113 2.79E-16 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_28135 7a05cee70671c1236aca2a3a34442276 249 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 121 206 3.0E-13 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_28135 7a05cee70671c1236aca2a3a34442276 249 SUPERFAMILY SSF56214 121 234 4.71E-21 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_28135 7a05cee70671c1236aca2a3a34442276 249 Gene3D G3DSA:3.90.470.20 33 236 7.3E-37 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_28135 7a05cee70671c1236aca2a3a34442276 249 Gene3D G3DSA:3.90.470.20 122 229 7.3E-37 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_28400 6ce4214dad17fba2adac38addc84f75b 213 SMART SM00014 87 200 6.5E-25 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_28400 6ce4214dad17fba2adac38addc84f75b 213 Gene3D G3DSA:1.20.144.10 3 118 1.9E-8 T 14-10-2018 C2I25_28400 6ce4214dad17fba2adac38addc84f75b 213 Gene3D G3DSA:1.20.144.10 119 212 8.0E-26 T 14-10-2018 C2I25_28400 6ce4214dad17fba2adac38addc84f75b 213 SUPERFAMILY SSF48317 5 205 1.7E-39 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I25_28400 6ce4214dad17fba2adac38addc84f75b 213 Pfam PF01569 PAP2 superfamily 97 205 8.5E-22 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_23570 9d612c2386623995cca2629141a107db 319 Pfam PF01139 tRNA-splicing ligase RtcB 53 317 2.0E-54 T 14-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 C2I25_23570 9d612c2386623995cca2629141a107db 319 SUPERFAMILY SSF103365 2 318 7.06E-80 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 C2I25_23570 9d612c2386623995cca2629141a107db 319 Gene3D G3DSA:3.90.1860.10 2 318 2.8E-54 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 C2I25_24155 94e1da24137cae1130e41a920ce12ca4 144 SUPERFAMILY SSF47240 10 139 1.06E-29 T 14-10-2018 IPR009078 Ferritin-like superfamily C2I25_24155 94e1da24137cae1130e41a920ce12ca4 144 Pfam PF02915 Rubrerythrin 92 140 3.5E-5 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 C2I25_24155 94e1da24137cae1130e41a920ce12ca4 144 Gene3D G3DSA:1.20.1260.10 10 92 1.1E-6 T 14-10-2018 IPR012347 Ferritin-like C2I25_24155 94e1da24137cae1130e41a920ce12ca4 144 Gene3D G3DSA:1.20.5.420 93 138 2.9E-10 T 14-10-2018 C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 SUPERFAMILY SSF51338 1 424 3.05E-31 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 SUPERFAMILY SSF51556 54 367 8.6E-114 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 Pfam PF01979 Amidohydrolase family 51 419 4.7E-53 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 Gene3D G3DSA:2.30.40.10 7 419 3.0E-174 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 423 45.816 T 14-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 422 5.1E-155 T 14-10-2018 C2I25_20055 abea9ae4e7c322b10aef045b9daaf0cc 428 Gene3D G3DSA:3.20.20.140 54 366 3.0E-174 T 14-10-2018 C2I25_03855 f111d4e8ea20a37d591bf39b4aa8da69 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 1.7E-226 T 14-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 C2I25_03855 f111d4e8ea20a37d591bf39b4aa8da69 492 Gene3D G3DSA:3.40.50.300 12 235 3.9E-10 T 14-10-2018 C2I25_03855 f111d4e8ea20a37d591bf39b4aa8da69 492 SUPERFAMILY SSF52540 21 236 2.83E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03855 f111d4e8ea20a37d591bf39b4aa8da69 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 7.0E-263 T 14-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 C2I25_03855 f111d4e8ea20a37d591bf39b4aa8da69 492 PIRSF PIRSF007466 1 492 2.2E-274 T 14-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 C2I25_25440 e61a8bc5003e83493be78f2d0cb78d21 213 SUPERFAMILY SSF109604 11 149 1.72E-14 T 14-10-2018 C2I25_25440 e61a8bc5003e83493be78f2d0cb78d21 213 Gene3D G3DSA:1.10.3210.10 9 192 2.6E-9 T 14-10-2018 C2I25_25440 e61a8bc5003e83493be78f2d0cb78d21 213 Pfam PF01966 HD domain 26 84 1.5E-6 T 14-10-2018 IPR006674 HD domain C2I25_25440 e61a8bc5003e83493be78f2d0cb78d21 213 SMART SM00471 21 160 1.0E-5 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 SUPERFAMILY SSF88659 114 190 1.92E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 1.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 1.6E-12 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 1.2E-157 T 14-10-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 255 8.9E-35 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 Gene3D G3DSA:1.20.140.160 113 258 5.2E-24 T 14-10-2018 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 Gene3D G3DSA:1.10.601.10 11 110 5.1E-27 T 14-10-2018 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 PIRSF PIRSF000770 159 259 5.9E-15 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 PIRSF PIRSF000770 115 157 0.37 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 PIRSF PIRSF000770 15 123 4.3E-18 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 1.5E-84 T 14-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 SUPERFAMILY SSF88659 175 258 8.04E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 SUPERFAMILY SSF88946 6 110 2.75E-33 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 Pfam PF04542 Sigma-70 region 2 42 110 2.4E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_19980 33972a883238293f706c4d9c1cea5e1d 259 Pfam PF04545 Sigma-70, region 4 207 253 1.7E-13 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_05310 7091728a443b5389a8f113b5c22a3d18 284 Pfam PF04321 RmlD substrate binding domain 4 279 1.2E-100 T 14-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 C2I25_05310 7091728a443b5389a8f113b5c22a3d18 284 Gene3D G3DSA:3.40.50.720 5 268 1.2E-113 T 14-10-2018 C2I25_05310 7091728a443b5389a8f113b5c22a3d18 284 Gene3D G3DSA:3.90.25.10 161 274 1.2E-113 T 14-10-2018 C2I25_05310 7091728a443b5389a8f113b5c22a3d18 284 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 4 278 3.2E-100 T 14-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 C2I25_05310 7091728a443b5389a8f113b5c22a3d18 284 SUPERFAMILY SSF51735 4 278 1.75E-90 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 Gene3D G3DSA:3.30.360.10 137 344 8.9E-149 T 14-10-2018 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 2.0E-21 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 Pfam PF00742 Homoserine dehydrogenase 138 316 9.5E-65 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 Gene3D G3DSA:3.40.50.720 5 336 8.9E-149 T 14-10-2018 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 Gene3D G3DSA:3.30.70.260 345 414 8.9E-149 T 14-10-2018 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 PIRSF PIRSF000098 2 427 1.4E-174 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 SUPERFAMILY SSF55347 138 303 3.27E-53 T 14-10-2018 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 SUPERFAMILY SSF55021 349 414 3.88E-8 T 14-10-2018 C2I25_01780 e037a8e3aec92e7321f94f600ef02243 431 SUPERFAMILY SSF51735 1 159 2.03E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_11035 549f817711fc77745411a28abcd3cfda 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 6.0E-107 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 C2I25_11035 549f817711fc77745411a28abcd3cfda 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 44.962 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 C2I25_11035 549f817711fc77745411a28abcd3cfda 230 PIRSF PIRSF002155 1 227 1.8E-82 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_11035 549f817711fc77745411a28abcd3cfda 230 Gene3D G3DSA:3.30.190.20 21 225 1.5E-85 T 14-10-2018 C2I25_11035 549f817711fc77745411a28abcd3cfda 230 SUPERFAMILY SSF56808 6 226 1.28E-85 T 14-10-2018 IPR023674 Ribosomal protein L1-like C2I25_11035 549f817711fc77745411a28abcd3cfda 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_11035 549f817711fc77745411a28abcd3cfda 230 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 8.6E-57 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein C2I25_11035 549f817711fc77745411a28abcd3cfda 230 Gene3D G3DSA:3.40.50.790 68 159 1.5E-85 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich C2I25_23500 2d1b16fd622b1e31a64814c078d5aeb8 227 Gene3D G3DSA:1.10.10.10 128 227 1.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23500 2d1b16fd622b1e31a64814c078d5aeb8 227 SMART SM00862 149 222 3.5E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_23500 2d1b16fd622b1e31a64814c078d5aeb8 227 SUPERFAMILY SSF52172 1 176 4.84E-39 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_23500 2d1b16fd622b1e31a64814c078d5aeb8 227 SMART SM00448 2 114 9.0E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_23500 2d1b16fd622b1e31a64814c078d5aeb8 227 Gene3D G3DSA:3.40.50.2300 1 127 8.2E-37 T 14-10-2018 C2I25_23500 2d1b16fd622b1e31a64814c078d5aeb8 227 Pfam PF00072 Response regulator receiver domain 4 114 7.6E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_23500 2d1b16fd622b1e31a64814c078d5aeb8 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 5.2E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00725 47 171 1.5E-10 T 14-10-2018 IPR006635 NEAT domain C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Gene3D G3DSA:2.60.40.1220 480 575 2.2E-15 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Gene3D G3DSA:3.80.10.10 356 479 1.3E-17 T 14-10-2018 IPR032675 Leucine-rich repeat domain superfamily C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SUPERFAMILY SSF52058 222 498 3.74E-50 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Pfam PF05031 Iron Transport-associated domain 48 164 3.7E-29 T 14-10-2018 IPR006635 NEAT domain C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Pfam PF00395 S-layer homology domain 594 636 4.2E-10 T 14-10-2018 IPR001119 S-layer homology domain C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Pfam PF00395 S-layer homology domain 654 695 7.5E-11 T 14-10-2018 IPR001119 S-layer homology domain C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Pfam PF00395 S-layer homology domain 714 757 1.3E-11 T 14-10-2018 IPR001119 S-layer homology domain C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SUPERFAMILY SSF158911 49 167 1.44E-29 T 14-10-2018 IPR037250 NEAT domain superfamily C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00369 313 334 75.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00369 291 311 23.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00369 444 467 9.1 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00369 335 358 54.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00369 422 443 390.0 T 14-10-2018 IPR003591 Leucine-rich repeat, typical subtype C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Pfam PF12799 Leucine Rich repeats (2 copies) 337 377 3.0E-7 T 14-10-2018 IPR025875 Leucine rich repeat 4 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Pfam PF12799 Leucine Rich repeats (2 copies) 423 464 1.2E-6 T 14-10-2018 IPR025875 Leucine rich repeat 4 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Pfam PF12799 Leucine Rich repeats (2 copies) 293 333 2.4E-10 T 14-10-2018 IPR025875 Leucine rich repeat 4 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 378 399 410.0 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 357 375 220.0 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 313 331 39.0 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 422 443 94.0 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 335 356 110.0 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 466 487 81.0 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 291 312 0.17 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 444 465 24.0 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SMART SM00365 400 421 3.4 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Gene3D G3DSA:2.60.40.1850 40 168 2.3E-36 T 14-10-2018 C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 Gene3D G3DSA:3.80.10.10 195 355 1.3E-34 T 14-10-2018 IPR032675 Leucine-rich repeat domain superfamily C2I25_04765 0ad8eb0d863ef22513bf44ceeb9d66b7 766 SUPERFAMILY SSF81296 500 575 4.01E-11 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_08975 a1a764634d5e301409286c2c0efb4f24 93 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 11 89 5.4E-31 T 14-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 C2I25_08975 a1a764634d5e301409286c2c0efb4f24 93 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 18 89 5.0E-28 T 14-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 C2I25_11545 54d8294f764d16b68c66a04e91aae5d5 211 Pfam PF01712 Deoxynucleoside kinase 7 204 4.3E-45 T 14-10-2018 IPR031314 Deoxynucleoside kinase domain C2I25_11545 54d8294f764d16b68c66a04e91aae5d5 211 Gene3D G3DSA:3.40.50.300 5 207 2.3E-46 T 14-10-2018 C2I25_11545 54d8294f764d16b68c66a04e91aae5d5 211 SUPERFAMILY SSF52540 5 205 1.36E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11545 54d8294f764d16b68c66a04e91aae5d5 211 PIRSF PIRSF000705 2 210 5.7E-56 T 14-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 C2I25_07430 4d6d9c1f4ddbc500eeae5e578e23bfce 159 Gene3D G3DSA:3.40.1260.10 1 159 1.1E-65 T 14-10-2018 IPR027396 DsrEFH-like C2I25_07430 4d6d9c1f4ddbc500eeae5e578e23bfce 159 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 158 1.1E-67 T 14-10-2018 IPR032836 DsrE2-like family C2I25_07430 4d6d9c1f4ddbc500eeae5e578e23bfce 159 SUPERFAMILY SSF75169 5 157 2.88E-23 T 14-10-2018 IPR027396 DsrEFH-like C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 428 9.4E-127 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 Pfam PF08245 Mur ligase middle domain 47 273 4.6E-12 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 Gene3D G3DSA:3.90.190.20 301 433 6.7E-34 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 Gene3D G3DSA:3.40.1190.10 1 298 5.3E-98 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 PIRSF PIRSF001563 1 433 6.1E-156 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 Pfam PF02875 Mur ligase family, glutamate ligase domain 301 373 2.7E-11 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 SUPERFAMILY SSF53244 301 431 1.47E-30 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_16995 be2b28b390e55e1f53131b20b89493ee 433 SUPERFAMILY SSF53623 3 299 1.22E-94 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_02355 4dded991f601cd05008830f22a2bfa1d 504 SUPERFAMILY SSF100950 227 496 2.18E-86 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_02355 4dded991f601cd05008830f22a2bfa1d 504 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 13 217 6.5E-23 T 14-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 C2I25_02355 4dded991f601cd05008830f22a2bfa1d 504 Gene3D G3DSA:3.30.750.70 247 326 5.4E-7 T 14-10-2018 C2I25_02355 4dded991f601cd05008830f22a2bfa1d 504 Gene3D G3DSA:3.40.1080.10 8 172 2.4E-11 T 14-10-2018 C2I25_02355 4dded991f601cd05008830f22a2bfa1d 504 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 322 465 5.0E-44 T 14-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain C2I25_02355 4dded991f601cd05008830f22a2bfa1d 504 Gene3D G3DSA:3.40.1080.20 338 478 1.0E-41 T 14-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily C2I25_02355 4dded991f601cd05008830f22a2bfa1d 504 SUPERFAMILY SSF100950 6 224 2.98E-62 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_02355 4dded991f601cd05008830f22a2bfa1d 504 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 13 496 4.0E-224 T 14-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 C2I25_03070 d096f4c1d879e8e03ae93261887b10d9 272 SUPERFAMILY SSF64518 1 272 8.76E-82 T 14-10-2018 C2I25_03070 d096f4c1d879e8e03ae93261887b10d9 272 PRINTS PR00207 Flagellin signature 109 132 2.0E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03070 d096f4c1d879e8e03ae93261887b10d9 272 PRINTS PR00207 Flagellin signature 35 52 2.0E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03070 d096f4c1d879e8e03ae93261887b10d9 272 PRINTS PR00207 Flagellin signature 74 93 2.0E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03070 d096f4c1d879e8e03ae93261887b10d9 272 Pfam PF00700 Bacterial flagellin C-terminal helical region 186 271 5.7E-24 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_03070 d096f4c1d879e8e03ae93261887b10d9 272 Gene3D G3DSA:1.20.1330.10 42 233 3.6E-50 T 14-10-2018 C2I25_03070 d096f4c1d879e8e03ae93261887b10d9 272 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 4.2E-37 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_03070 d096f4c1d879e8e03ae93261887b10d9 272 Gene3D G3DSA:1.20.120.2000 234 272 1.5E-12 T 14-10-2018 C2I25_24020 593a07d417bcc00a4d5de9d10185a1af 341 SUPERFAMILY SSF53067 5 166 3.11E-7 T 14-10-2018 C2I25_24020 593a07d417bcc00a4d5de9d10185a1af 341 Gene3D G3DSA:3.30.420.40 171 308 9.5E-27 T 14-10-2018 C2I25_24020 593a07d417bcc00a4d5de9d10185a1af 341 Gene3D G3DSA:3.30.420.40 6 324 9.5E-27 T 14-10-2018 C2I25_28460 d773cfccdbc449f93175e791eae42dba 422 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 409 6.2E-117 T 14-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase C2I25_28460 d773cfccdbc449f93175e791eae42dba 422 Gene3D G3DSA:3.30.70.360 204 330 2.3E-139 T 14-10-2018 C2I25_28460 d773cfccdbc449f93175e791eae42dba 422 SUPERFAMILY SSF53187 5 419 3.83E-63 T 14-10-2018 C2I25_28460 d773cfccdbc449f93175e791eae42dba 422 Pfam PF07687 Peptidase dimerisation domain 202 310 2.2E-17 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_28460 d773cfccdbc449f93175e791eae42dba 422 Gene3D G3DSA:3.40.630.10 27 418 2.3E-139 T 14-10-2018 C2I25_28460 d773cfccdbc449f93175e791eae42dba 422 Pfam PF01546 Peptidase family M20/M25/M40 97 415 4.4E-38 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_28460 d773cfccdbc449f93175e791eae42dba 422 SUPERFAMILY SSF55031 203 310 1.64E-13 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_06545 411b790140b845cdd22a1aedf6284052 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 54 1.6E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06545 411b790140b845cdd22a1aedf6284052 188 Pfam PF14278 Transcriptional regulator C-terminal region 78 157 4.4E-15 T 14-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type C2I25_06545 411b790140b845cdd22a1aedf6284052 188 Gene3D G3DSA:1.10.357.10 1 187 1.3E-52 T 14-10-2018 C2I25_06545 411b790140b845cdd22a1aedf6284052 188 TIGRFAM TIGR02366 DHAK_reg: probable dihydroxyacetone kinase regulator 4 179 3.1E-79 T 14-10-2018 IPR012738 Transcription regulator DhaS C2I25_06545 411b790140b845cdd22a1aedf6284052 188 SUPERFAMILY SSF46689 5 63 6.67E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_03130 25c7134231c694afcd748a35946d143f 334 Gene3D G3DSA:1.10.220.30 2 87 2.7E-16 T 14-10-2018 C2I25_03130 25c7134231c694afcd748a35946d143f 334 Pfam PF01706 FliG C-terminal domain 218 324 8.0E-31 T 14-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal C2I25_03130 25c7134231c694afcd748a35946d143f 334 SUPERFAMILY SSF48029 115 326 3.27E-49 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical C2I25_03130 25c7134231c694afcd748a35946d143f 334 Gene3D G3DSA:1.10.220.30 196 334 3.5E-36 T 14-10-2018 C2I25_03130 25c7134231c694afcd748a35946d143f 334 Pfam PF14841 FliG middle domain 118 186 1.6E-18 T 14-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain C2I25_03130 25c7134231c694afcd748a35946d143f 334 Pfam PF14842 FliG N-terminal domain 5 101 1.9E-16 T 14-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain C2I25_03130 25c7134231c694afcd748a35946d143f 334 Gene3D G3DSA:1.10.220.30 102 194 4.4E-22 T 14-10-2018 C2I25_03130 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 5 21 5.9E-40 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I25_03130 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 114 137 5.9E-40 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I25_03130 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 195 220 5.9E-40 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I25_03130 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 226 246 5.9E-40 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I25_03130 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 273 299 5.9E-40 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I25_03130 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 34 60 5.9E-40 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I25_03130 25c7134231c694afcd748a35946d143f 334 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 2 333 1.6E-68 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I25_03130 25c7134231c694afcd748a35946d143f 334 SUPERFAMILY SSF48029 8 112 4.84E-15 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical C2I25_11995 4cece655b465437877d7e2582a78db2a 321 Pfam PF01625 Peptide methionine sulfoxide reductase 10 159 2.2E-59 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_11995 4cece655b465437877d7e2582a78db2a 321 Gene3D G3DSA:2.170.150.20 177 319 5.6E-59 T 14-10-2018 C2I25_11995 4cece655b465437877d7e2582a78db2a 321 SUPERFAMILY SSF55068 3 171 6.02E-71 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_11995 4cece655b465437877d7e2582a78db2a 321 Gene3D G3DSA:3.30.1060.10 1 172 1.2E-63 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_11995 4cece655b465437877d7e2582a78db2a 321 Pfam PF01641 SelR domain 183 301 3.8E-48 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 C2I25_11995 4cece655b465437877d7e2582a78db2a 321 SUPERFAMILY SSF51316 178 317 7.85E-60 T 14-10-2018 IPR011057 Mss4-like superfamily C2I25_11995 4cece655b465437877d7e2582a78db2a 321 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 172 302 37.917 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 C2I25_11995 4cece655b465437877d7e2582a78db2a 321 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 7 166 35.874 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_11995 4cece655b465437877d7e2582a78db2a 321 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 8 159 1.8E-59 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_11995 4cece655b465437877d7e2582a78db2a 321 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 179 310 2.0E-64 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 C2I25_26605 df0c31d9a6b17a64f968095e442c389b 556 Pfam PF03354 Phage Terminase 73 511 4.5E-35 T 14-10-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type C2I25_26605 df0c31d9a6b17a64f968095e442c389b 556 Gene3D G3DSA:3.40.50.300 16 250 1.3E-13 T 14-10-2018 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Gene3D G3DSA:2.30.30.940 598 677 3.8E-140 T 14-10-2018 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Pfam PF13604 AAA domain 341 548 1.2E-49 T 14-10-2018 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Gene3D G3DSA:1.10.150.20 94 157 2.2E-5 T 14-10-2018 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Gene3D G3DSA:1.10.10.2220 198 307 1.9E-14 T 14-10-2018 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Gene3D G3DSA:3.40.50.300 512 740 3.8E-140 T 14-10-2018 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 14 753 29.633 T 14-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Pfam PF14490 Helix-hairpin-helix containing domain 156 247 5.1E-29 T 14-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 SUPERFAMILY SSF52540 335 729 1.89E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Gene3D G3DSA:3.40.50.300 325 746 3.8E-140 T 14-10-2018 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 20 750 9.2E-246 T 14-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 C2I25_17305 e8460e10d5096bed29650ceff1bc54bf 778 Pfam PF13538 UvrD-like helicase C-terminal domain 676 724 3.7E-16 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain C2I25_19680 c117e85fb51ee360cbbcb193fb2caf8f 493 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 224 238 - T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 C2I25_19680 c117e85fb51ee360cbbcb193fb2caf8f 493 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 9 372 6.2E-114 T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 C2I25_19680 c117e85fb51ee360cbbcb193fb2caf8f 493 SUPERFAMILY SSF55904 345 488 1.96E-39 T 14-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 C2I25_19680 c117e85fb51ee360cbbcb193fb2caf8f 493 Gene3D G3DSA:3.90.1150.10 312 410 2.6E-6 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_19680 c117e85fb51ee360cbbcb193fb2caf8f 493 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 406 463 7.0E-10 T 14-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 C2I25_19680 c117e85fb51ee360cbbcb193fb2caf8f 493 SUPERFAMILY SSF53383 9 388 2.15E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_19680 c117e85fb51ee360cbbcb193fb2caf8f 493 Gene3D G3DSA:3.90.105.10 423 480 1.3E-18 T 14-10-2018 C2I25_19680 c117e85fb51ee360cbbcb193fb2caf8f 493 Gene3D G3DSA:3.40.640.10 9 285 3.9E-94 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Pfam PF14450 Cell division protein FtsA 9 188 4.5E-10 T 14-10-2018 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 SUPERFAMILY SSF53067 197 368 1.08E-41 T 14-10-2018 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Pfam PF14450 Cell division protein FtsA 205 366 2.9E-22 T 14-10-2018 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Gene3D G3DSA:3.30.420.40 195 349 1.1E-107 T 14-10-2018 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Gene3D G3DSA:3.30.1490.110 83 167 1.1E-107 T 14-10-2018 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 370 435 1.3E-8 T 14-10-2018 IPR021873 Cell division protein FtsA, C-terminal C2I25_19960 82ebb5c6a9af57005d25258349328445 435 PIRSF PIRSF003101 1 434 1.1E-144 T 14-10-2018 IPR020823 Cell division protein FtsA C2I25_19960 82ebb5c6a9af57005d25258349328445 435 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 3.2E-121 T 14-10-2018 IPR020823 Cell division protein FtsA C2I25_19960 82ebb5c6a9af57005d25258349328445 435 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 206 219 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Gene3D G3DSA:3.90.640.10 233 298 1.1E-107 T 14-10-2018 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 434 30.519 T 14-10-2018 IPR020823 Cell division protein FtsA C2I25_19960 82ebb5c6a9af57005d25258349328445 435 SUPERFAMILY SSF53067 6 192 8.43E-57 T 14-10-2018 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Pfam PF02491 SHS2 domain inserted in FTSA 83 160 5.9E-24 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 SMART SM00842 7 194 2.2E-92 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 C2I25_19960 82ebb5c6a9af57005d25258349328445 435 Gene3D G3DSA:3.30.420.40 10 354 1.1E-107 T 14-10-2018 C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.0E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.0E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.0E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.0E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.0E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.0E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 236 1.5E-45 T 14-10-2018 C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 Gene3D G3DSA:3.40.50.720 1 237 2.4E-61 T 14-10-2018 C2I25_20585 50008c7b45b96165e806eb7e0116232a 237 SUPERFAMILY SSF51735 2 236 1.69E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_14935 808d2b8699f871a6b3bebbb364b5f4c1 366 SUPERFAMILY SSF51338 5 363 7.13E-13 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_14935 808d2b8699f871a6b3bebbb364b5f4c1 366 Gene3D G3DSA:3.20.20.140 52 316 4.0E-114 T 14-10-2018 C2I25_14935 808d2b8699f871a6b3bebbb364b5f4c1 366 Gene3D G3DSA:2.30.40.10 7 361 4.0E-114 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_14935 808d2b8699f871a6b3bebbb364b5f4c1 366 SUPERFAMILY SSF51556 52 316 2.34E-65 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_14935 808d2b8699f871a6b3bebbb364b5f4c1 366 PIRSF PIRSF039004 1 366 2.4E-137 T 14-10-2018 IPR020043 Deacetylase Atu3266-like GO:0019213 C2I25_14935 808d2b8699f871a6b3bebbb364b5f4c1 366 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 4 364 1.6E-174 T 14-10-2018 IPR020043 Deacetylase Atu3266-like GO:0019213 C2I25_06565 b82fecab805c3e43389c98511033a366 103 SMART SM00418 5 100 5.3E-4 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_06565 b82fecab805c3e43389c98511033a366 103 Gene3D G3DSA:1.10.10.10 2 103 2.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_06565 b82fecab805c3e43389c98511033a366 103 SUPERFAMILY SSF46785 4 101 1.43E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01815 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.3E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_01815 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_01815 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.3E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_01815 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.3E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_01815 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.3E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_01815 1bbce933c1ee9393685515675152b089 242 PIRSF PIRSF000126 4 241 6.9E-64 T 14-10-2018 C2I25_01815 1bbce933c1ee9393685515675152b089 242 Pfam PF00106 short chain dehydrogenase 11 199 2.0E-66 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_01815 1bbce933c1ee9393685515675152b089 242 SUPERFAMILY SSF51735 8 228 1.68E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_01815 1bbce933c1ee9393685515675152b089 242 Gene3D G3DSA:3.40.50.720 5 239 5.0E-74 T 14-10-2018 C2I25_01815 1bbce933c1ee9393685515675152b089 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_01815 1bbce933c1ee9393685515675152b089 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.4E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_01815 1bbce933c1ee9393685515675152b089 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.4E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_01815 1bbce933c1ee9393685515675152b089 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.4E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15105 55d1845b72952caf467861e11a52d991 175 Gene3D G3DSA:3.40.50.2020 1 175 2.4E-66 T 14-10-2018 C2I25_15105 55d1845b72952caf467861e11a52d991 175 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 172 1.2E-64 T 14-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 C2I25_15105 55d1845b72952caf467861e11a52d991 175 Pfam PF00156 Phosphoribosyl transferase domain 13 158 2.5E-25 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_15105 55d1845b72952caf467861e11a52d991 175 SUPERFAMILY SSF53271 4 174 8.07E-54 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Gene3D G3DSA:3.40.50.300 1 202 1.4E-75 T 14-10-2018 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 SMART SM00490 243 324 5.5E-28 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Pfam PF14493 Helix-turn-helix domain 614 701 4.5E-27 T 14-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 SUPERFAMILY SSF52540 58 345 1.17E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 5 583 3.6E-233 T 14-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Pfam PF00271 Helicase conserved C-terminal domain 218 323 3.3E-18 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 SMART SM00341 512 592 5.0E-20 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 SMART SM00956 404 507 1.1E-41 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Pfam PF09382 RQC domain 400 509 8.0E-32 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 SMART SM00487 14 211 1.8E-28 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Pfam PF00570 HRDC domain 517 582 3.7E-22 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 SUPERFAMILY SSF47819 515 589 4.36E-24 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 453 4.3E-145 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 SUPERFAMILY SSF46785 395 537 9.33E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Pfam PF00270 DEAD/DEAH box helicase 21 181 1.0E-20 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Gene3D G3DSA:1.10.150.80 511 591 1.3E-24 T 14-10-2018 C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Gene3D G3DSA:1.10.10.10 334 510 9.1E-47 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Pfam PF16124 RecQ zinc-binding 336 396 4.1E-16 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain C2I25_25510 5e848b1d651a724482cbab8a3e09c0b2 705 Gene3D G3DSA:3.40.50.300 203 333 7.6E-41 T 14-10-2018 C2I25_25555 a1ce29922e2ec4e840a094f33adf9794 170 Gene3D G3DSA:3.40.630.30 1 170 8.4E-53 T 14-10-2018 C2I25_25555 a1ce29922e2ec4e840a094f33adf9794 170 Pfam PF13420 Acetyltransferase (GNAT) domain 2 153 8.7E-24 T 14-10-2018 C2I25_25555 a1ce29922e2ec4e840a094f33adf9794 170 SUPERFAMILY SSF55729 1 163 3.6E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_00150 f449933d4d90c689541d8bdde8174103 372 Pfam PF13185 GAF domain 25 168 5.1E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_00150 f449933d4d90c689541d8bdde8174103 372 Gene3D G3DSA:3.30.565.10 243 372 3.1E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_00150 f449933d4d90c689541d8bdde8174103 372 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 371 5.7E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_00150 f449933d4d90c689541d8bdde8174103 372 SUPERFAMILY SSF55874 252 371 1.31E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_00150 f449933d4d90c689541d8bdde8174103 372 Gene3D G3DSA:3.30.450.40 9 178 1.9E-22 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_00150 f449933d4d90c689541d8bdde8174103 372 SMART SM00065 26 177 0.0013 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_00150 f449933d4d90c689541d8bdde8174103 372 SUPERFAMILY SSF55781 27 172 5.67E-19 T 14-10-2018 C2I25_00150 f449933d4d90c689541d8bdde8174103 372 Pfam PF07730 Histidine kinase 184 248 2.6E-15 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I25_13940 ac432e64a95b4a0181bd32e2eae656ae 235 Pfam PF11368 Protein of unknown function (DUF3169) 44 228 3.9E-13 T 14-10-2018 IPR021509 Protein of unknown function DUF3169 C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 SUPERFAMILY SSF49478 294 357 7.85E-10 T 14-10-2018 C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 SUPERFAMILY SSF49478 478 538 7.06E-8 T 14-10-2018 C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 Gene3D G3DSA:2.60.40.10 373 460 1.0E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 Gene3D G3DSA:2.60.40.10 461 549 4.9E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 Gene3D G3DSA:2.60.40.10 284 372 2.4E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 Gene3D G3DSA:2.60.40.10 550 651 3.6E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 Pfam PF00746 LPXTG cell wall anchor motif 1060 1092 6.2E-4 T 14-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1060 1092 2.8E-6 T 14-10-2018 C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 Gene3D G3DSA:2.60.40.3930 652 775 1.1E-25 T 14-10-2018 C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 Gene3D G3DSA:2.60.40.3930 776 897 3.5E-25 T 14-10-2018 C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 Gene3D G3DSA:2.60.40.3930 898 1022 8.7E-25 T 14-10-2018 C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 SUPERFAMILY SSF49478 563 630 7.06E-9 T 14-10-2018 C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 89 128 1.8E-11 T 14-10-2018 IPR023849 Uncharacterised domain CHP03934, TQXA C2I25_21950 6902b5e8aaeb4e46b52083be14e6a490 1093 SUPERFAMILY SSF49478 383 443 1.33E-7 T 14-10-2018 C2I25_21810 ce4134e0ffc2a27d62cc8dc026facfb3 494 Gene3D G3DSA:3.40.309.10 270 459 2.0E-202 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_21810 ce4134e0ffc2a27d62cc8dc026facfb3 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I25_21810 ce4134e0ffc2a27d62cc8dc026facfb3 494 Pfam PF00171 Aldehyde dehydrogenase family 29 489 7.6E-192 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_21810 ce4134e0ffc2a27d62cc8dc026facfb3 494 Gene3D G3DSA:3.40.605.10 24 487 2.0E-202 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_21810 ce4134e0ffc2a27d62cc8dc026facfb3 494 SUPERFAMILY SSF53720 15 492 5.89E-183 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_08340 189c482053559c7357d9f95308b9129d 236 Gene3D G3DSA:3.40.1410.10 74 231 1.2E-33 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_08340 189c482053559c7357d9f95308b9129d 236 SMART SM00866 89 228 3.5E-32 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_08340 189c482053559c7357d9f95308b9129d 236 Pfam PF07702 UTRA domain 90 227 7.7E-37 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_08340 189c482053559c7357d9f95308b9129d 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 5.2E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_08340 189c482053559c7357d9f95308b9129d 236 SMART SM00345 8 67 4.3E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_08340 189c482053559c7357d9f95308b9129d 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.3E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_08340 189c482053559c7357d9f95308b9129d 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.3E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_08340 189c482053559c7357d9f95308b9129d 236 SUPERFAMILY SSF64288 55 235 1.88E-43 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_08340 189c482053559c7357d9f95308b9129d 236 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 4 235 2.2E-106 T 14-10-2018 IPR012770 Trehalose operon transcriptional repressor C2I25_08340 189c482053559c7357d9f95308b9129d 236 SUPERFAMILY SSF46785 2 71 2.45E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08340 189c482053559c7357d9f95308b9129d 236 Gene3D G3DSA:1.10.10.10 1 67 2.4E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_27560 45bc4b9ddf62dbf9a0ca176b74b4e0d4 135 Gene3D G3DSA:3.30.720.100 10 74 1.6E-33 T 14-10-2018 C2I25_27560 45bc4b9ddf62dbf9a0ca176b74b4e0d4 135 SUPERFAMILY SSF54593 6 132 2.97E-40 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_27560 45bc4b9ddf62dbf9a0ca176b74b4e0d4 135 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 132 4.2E-45 T 14-10-2018 IPR028973 PhnB-like C2I25_27560 45bc4b9ddf62dbf9a0ca176b74b4e0d4 135 Gene3D G3DSA:3.30.720.110 75 135 3.7E-32 T 14-10-2018 C2I25_27560 45bc4b9ddf62dbf9a0ca176b74b4e0d4 135 PIRSF PIRSF500687 1 135 3.3E-70 T 14-10-2018 IPR027259 Predicted 3-demethylubiquinone-9 3-methyltransferase, bacterial C2I25_27560 45bc4b9ddf62dbf9a0ca176b74b4e0d4 135 PIRSF PIRSF021700 3 135 3.9E-45 T 14-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase C2I25_10900 3a58915a4d26a51e2837a10f56cbee63 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10900 3a58915a4d26a51e2837a10f56cbee63 132 Gene3D G3DSA:3.30.1370.30 4 74 2.8E-34 T 14-10-2018 C2I25_10900 3a58915a4d26a51e2837a10f56cbee63 132 Gene3D G3DSA:3.30.1490.10 75 132 9.9E-26 T 14-10-2018 C2I25_10900 3a58915a4d26a51e2837a10f56cbee63 132 SUPERFAMILY SSF56047 2 132 3.27E-49 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10900 3a58915a4d26a51e2837a10f56cbee63 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.966 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10900 3a58915a4d26a51e2837a10f56cbee63 132 Pfam PF00410 Ribosomal protein S8 5 132 3.9E-54 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_17995 45e6087d52e0c1c78b4dc85d5766924c 96 SUPERFAMILY SSF46785 5 95 1.37E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_17995 45e6087d52e0c1c78b4dc85d5766924c 96 SMART SM00418 17 96 6.4E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_17995 45e6087d52e0c1c78b4dc85d5766924c 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 2.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_17995 45e6087d52e0c1c78b4dc85d5766924c 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_17995 45e6087d52e0c1c78b4dc85d5766924c 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 2.3E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_17995 45e6087d52e0c1c78b4dc85d5766924c 96 Pfam PF12840 Helix-turn-helix domain 16 75 9.0E-10 T 14-10-2018 C2I25_17995 45e6087d52e0c1c78b4dc85d5766924c 96 Gene3D G3DSA:1.10.10.10 2 95 5.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04265 76a387642ac59e4a2b2ce0ae0786e432 204 Gene3D G3DSA:3.40.50.720 1 127 2.5E-38 T 14-10-2018 C2I25_04265 76a387642ac59e4a2b2ce0ae0786e432 204 SUPERFAMILY SSF75615 106 194 1.12E-20 T 14-10-2018 C2I25_04265 76a387642ac59e4a2b2ce0ae0786e432 204 Gene3D G3DSA:1.10.8.610 128 201 2.3E-24 T 14-10-2018 C2I25_04265 76a387642ac59e4a2b2ce0ae0786e432 204 Pfam PF13241 Putative NAD(P)-binding 4 112 1.8E-26 T 14-10-2018 C2I25_04265 76a387642ac59e4a2b2ce0ae0786e432 204 SUPERFAMILY SSF51735 1 107 2.58E-18 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_04265 76a387642ac59e4a2b2ce0ae0786e432 204 Pfam PF14824 Sirohaem biosynthesis protein central 116 142 6.9E-11 T 14-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_04265 76a387642ac59e4a2b2ce0ae0786e432 204 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 187 4.1E-40 T 14-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I25_21005 8aa5855df8f7d507612735144aa915bf 129 Pfam PF13411 MerR HTH family regulatory protein 13 76 3.7E-18 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_21005 8aa5855df8f7d507612735144aa915bf 129 SMART SM00422 11 79 6.8E-24 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_21005 8aa5855df8f7d507612735144aa915bf 129 Gene3D G3DSA:1.10.1660.10 2 83 8.2E-24 T 14-10-2018 C2I25_21005 8aa5855df8f7d507612735144aa915bf 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 14 36 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_21005 8aa5855df8f7d507612735144aa915bf 129 SUPERFAMILY SSF46955 11 90 3.85E-18 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_07325 cb9b8b8bb5f112b59acf6e1e2aa39b19 279 Gene3D G3DSA:1.10.3720.10 57 271 5.9E-10 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07325 cb9b8b8bb5f112b59acf6e1e2aa39b19 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 275 2.0E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_07325 cb9b8b8bb5f112b59acf6e1e2aa39b19 279 SUPERFAMILY SSF161098 61 263 7.85E-10 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_15505 4a3c84c07afa55ed20278bcc4ea908fd 319 SUPERFAMILY SSF102114 5 308 1.15E-52 T 14-10-2018 C2I25_15505 4a3c84c07afa55ed20278bcc4ea908fd 319 Pfam PF04055 Radical SAM superfamily 52 214 1.5E-14 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_15505 4a3c84c07afa55ed20278bcc4ea908fd 319 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 15 312 1.1E-127 T 14-10-2018 IPR005911 Protein YhcC-like GO:0051536 C2I25_15505 4a3c84c07afa55ed20278bcc4ea908fd 319 Gene3D G3DSA:3.20.20.70 49 258 1.4E-13 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_15505 4a3c84c07afa55ed20278bcc4ea908fd 319 SMART SM00729 32 259 2.8E-42 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_15505 4a3c84c07afa55ed20278bcc4ea908fd 319 Pfam PF16199 Radical_SAM C-terminal domain 220 302 4.2E-25 T 14-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 C2I25_12620 fd91fe82b749c9e0e0ec8011a675d45b 130 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 130 1.0E-47 T 14-10-2018 C2I25_12620 fd91fe82b749c9e0e0ec8011a675d45b 130 Pfam PF03899 ATP synthase I chain 11 109 5.6E-15 T 14-10-2018 IPR005598 ATP synthase protein I C2I25_22660 c1e40466a6884b9a673d5256c569f980 488 Pfam PF00005 ABC transporter 259 413 1.3E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_22660 c1e40466a6884b9a673d5256c569f980 488 Gene3D G3DSA:3.40.50.300 230 485 4.6E-75 T 14-10-2018 C2I25_22660 c1e40466a6884b9a673d5256c569f980 488 SUPERFAMILY SSF52540 240 483 1.61E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_22660 c1e40466a6884b9a673d5256c569f980 488 Gene3D G3DSA:1.20.1560.10 1 223 9.9E-11 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_22660 c1e40466a6884b9a673d5256c569f980 488 SMART SM00382 268 459 6.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_22660 c1e40466a6884b9a673d5256c569f980 488 SUPERFAMILY SSF90123 14 212 6.41E-15 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_22660 c1e40466a6884b9a673d5256c569f980 488 ProSitePatterns PS00211 ABC transporters family signature. 385 399 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_24140 1e4fa10054be6e591383f13f9e8e600f 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 8.1E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24140 1e4fa10054be6e591383f13f9e8e600f 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 8.1E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24140 1e4fa10054be6e591383f13f9e8e600f 211 Gene3D G3DSA:1.10.357.10 13 199 5.0E-53 T 14-10-2018 C2I25_24140 1e4fa10054be6e591383f13f9e8e600f 211 SUPERFAMILY SSF46689 14 77 1.85E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_24140 1e4fa10054be6e591383f13f9e8e600f 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 4.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24140 1e4fa10054be6e591383f13f9e8e600f 211 Pfam PF14278 Transcriptional regulator C-terminal region 105 181 3.5E-21 T 14-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type C2I25_14220 c1829891cc3c701f142511dc6db01eec 100 Gene3D G3DSA:3.30.1980.10 1 100 1.5E-24 T 14-10-2018 IPR036493 Hypothetical protein YunC superfamily C2I25_14220 c1829891cc3c701f142511dc6db01eec 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 3.8E-23 T 14-10-2018 IPR014931 Protein of unknown function DUF1805 C2I25_14220 c1829891cc3c701f142511dc6db01eec 100 SUPERFAMILY SSF102891 1 99 1.7E-34 T 14-10-2018 IPR036493 Hypothetical protein YunC superfamily C2I25_18425 ef2c8d90885b437630c6543b6af4ceef 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 15.072 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I25_18425 ef2c8d90885b437630c6543b6af4ceef 76 Pfam PF02609 Exonuclease VII small subunit 7 57 3.2E-20 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I25_18425 ef2c8d90885b437630c6543b6af4ceef 76 PIRSF PIRSF006488 1 76 1.1E-19 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I25_18425 ef2c8d90885b437630c6543b6af4ceef 76 SUPERFAMILY SSF116842 3 66 3.4E-21 T 14-10-2018 C2I25_18425 ef2c8d90885b437630c6543b6af4ceef 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 47 9.0E-20 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I25_18425 ef2c8d90885b437630c6543b6af4ceef 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 61 4.6E-22 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I25_18425 ef2c8d90885b437630c6543b6af4ceef 76 Gene3D G3DSA:1.10.287.1040 1 75 7.4E-22 T 14-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 C2I25_28000 01aa6322327bd8db11a2ae21c853349d 135 Gene3D G3DSA:3.40.630.30 5 130 2.3E-24 T 14-10-2018 C2I25_28000 01aa6322327bd8db11a2ae21c853349d 135 Pfam PF13673 Acetyltransferase (GNAT) domain 35 125 1.9E-11 T 14-10-2018 IPR000182 GNAT domain C2I25_28000 01aa6322327bd8db11a2ae21c853349d 135 SUPERFAMILY SSF55729 10 127 1.08E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26945 d8d2d56e0d3ec69e346e86eeab38f414 250 Pfam PF13649 Methyltransferase domain 50 131 1.1E-12 T 14-10-2018 C2I25_26945 d8d2d56e0d3ec69e346e86eeab38f414 250 SUPERFAMILY SSF53335 39 204 2.39E-22 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_26945 d8d2d56e0d3ec69e346e86eeab38f414 250 Gene3D G3DSA:3.40.50.150 21 229 2.8E-19 T 14-10-2018 C2I25_07210 19835b7bc702395002de3fff2661f3fe 357 Gene3D G3DSA:2.40.100.10 243 356 4.4E-38 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_07210 19835b7bc702395002de3fff2661f3fe 357 Gene3D G3DSA:3.20.20.70 1 236 1.6E-86 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_07210 19835b7bc702395002de3fff2661f3fe 357 SUPERFAMILY SSF50891 242 350 1.1E-32 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_07210 19835b7bc702395002de3fff2661f3fe 357 SUPERFAMILY SSF51445 1 234 1.26E-77 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_07210 19835b7bc702395002de3fff2661f3fe 357 Pfam PF05913 Bacterial protein of unknown function (DUF871) 1 349 2.6E-120 T 14-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic C2I25_11825 9b78159abdf52e7abb8444ef36062568 292 Pfam PF13186 Iron-sulfur cluster-binding domain 219 284 4.4E-12 T 14-10-2018 IPR023885 4Fe4S-binding SPASM domain C2I25_11825 9b78159abdf52e7abb8444ef36062568 292 Pfam PF04055 Radical SAM superfamily 10 113 6.0E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_11825 9b78159abdf52e7abb8444ef36062568 292 SUPERFAMILY SSF102114 7 287 8.11E-36 T 14-10-2018 C2I25_11825 9b78159abdf52e7abb8444ef36062568 292 Pfam PF13394 4Fe-4S single cluster domain 12 89 3.5E-5 T 14-10-2018 C2I25_16980 83a422c2d2c9035fcb1d29e483b9050e 326 TIGRFAM TIGR02907 spore_VI_D: stage VI sporulation protein D 7 319 9.6E-131 T 14-10-2018 IPR014256 Sporulation stage VI, protein D C2I25_16980 83a422c2d2c9035fcb1d29e483b9050e 326 Pfam PF01476 LysM domain 277 319 1.1E-6 T 14-10-2018 IPR018392 LysM domain C2I25_16980 83a422c2d2c9035fcb1d29e483b9050e 326 Gene3D G3DSA:3.10.350.10 264 325 1.4E-10 T 14-10-2018 IPR036779 LysM domain superfamily C2I25_16980 83a422c2d2c9035fcb1d29e483b9050e 326 SUPERFAMILY SSF54106 275 320 3.14E-9 T 14-10-2018 C2I25_16980 83a422c2d2c9035fcb1d29e483b9050e 326 SMART SM00257 276 319 6.7E-5 T 14-10-2018 IPR018392 LysM domain C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 324 8.7E-119 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 Gene3D G3DSA:1.10.240.10 183 293 8.0E-141 T 14-10-2018 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 SUPERFAMILY SSF52374 3 324 4.03E-101 T 14-10-2018 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 325 42.98 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 2.1E-29 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 160 2.1E-29 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 2.1E-29 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 2.1E-29 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 Pfam PF00579 tRNA synthetases class I (W and Y) 3 278 3.9E-85 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_05510 55ec7a64ecc6f00deb35be3d4aef02b5 329 Gene3D G3DSA:3.40.50.620 4 323 8.0E-141 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_03120 4f244d6ee44fdeea82abb221f51d5153 434 SUPERFAMILY SSF52540 93 358 7.36E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03120 4f244d6ee44fdeea82abb221f51d5153 434 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 3 433 2.4E-144 T 14-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_03120 4f244d6ee44fdeea82abb221f51d5153 434 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 25 433 2.0E-190 T 14-10-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_03120 4f244d6ee44fdeea82abb221f51d5153 434 Gene3D G3DSA:3.40.50.12240 17 434 3.4E-121 T 14-10-2018 C2I25_03120 4f244d6ee44fdeea82abb221f51d5153 434 SMART SM00382 157 337 2.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_03120 4f244d6ee44fdeea82abb221f51d5153 434 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 353 7.2E-62 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_20850 8339fd2536bf0ad3af2444af2c158097 273 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_20850 8339fd2536bf0ad3af2444af2c158097 273 SUPERFAMILY SSF52540 3 231 2.92E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20850 8339fd2536bf0ad3af2444af2c158097 273 Pfam PF00005 ABC transporter 20 167 1.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_20850 8339fd2536bf0ad3af2444af2c158097 273 Gene3D G3DSA:3.40.50.300 1 254 3.1E-68 T 14-10-2018 C2I25_20850 8339fd2536bf0ad3af2444af2c158097 273 SMART SM00382 28 217 1.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26485 db044d0341a989e3e88aac51120740b3 334 Pfam PF12395 Protein of unknown function 224 329 7.7E-31 T 14-10-2018 IPR022123 Protein of unknown function DUF3658 C2I25_26485 db044d0341a989e3e88aac51120740b3 334 Pfam PF08874 Domain of unknown function (DUF1835) 66 187 8.6E-31 T 14-10-2018 IPR014973 Protein of unknown function DUF1835 C2I25_08570 e49324439e954041cd8c14dbd35f6abe 170 Pfam PF00583 Acetyltransferase (GNAT) family 37 140 2.1E-19 T 14-10-2018 IPR000182 GNAT domain C2I25_08570 e49324439e954041cd8c14dbd35f6abe 170 Gene3D G3DSA:3.40.630.30 1 170 5.6E-43 T 14-10-2018 C2I25_08570 e49324439e954041cd8c14dbd35f6abe 170 SUPERFAMILY SSF55729 6 168 6.08E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27400 4fc86d2cb8e9d5133a94ce0826d471e1 234 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 97 199 8.1E-15 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I25_27400 4fc86d2cb8e9d5133a94ce0826d471e1 234 Gene3D G3DSA:3.90.470.20 9 212 4.4E-76 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_27400 4fc86d2cb8e9d5133a94ce0826d471e1 234 SUPERFAMILY SSF56214 7 91 2.77E-22 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_27400 4fc86d2cb8e9d5133a94ce0826d471e1 234 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 99 195 3.6E-18 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_27400 4fc86d2cb8e9d5133a94ce0826d471e1 234 SUPERFAMILY SSF56214 98 213 1.7E-26 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_27400 4fc86d2cb8e9d5133a94ce0826d471e1 234 Gene3D G3DSA:3.90.470.20 99 200 4.4E-76 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_17620 02cd2d9c30e7aa23bef11e85d05d0124 189 Gene3D G3DSA:1.10.3210.10 1 186 1.6E-59 T 14-10-2018 C2I25_17620 02cd2d9c30e7aa23bef11e85d05d0124 189 Pfam PF01966 HD domain 18 130 4.4E-15 T 14-10-2018 IPR006674 HD domain C2I25_17620 02cd2d9c30e7aa23bef11e85d05d0124 189 TIGRFAM TIGR00277 HDIG: HDIG domain 15 94 5.8E-8 T 14-10-2018 IPR006675 HDIG domain C2I25_17620 02cd2d9c30e7aa23bef11e85d05d0124 189 SMART SM00471 14 141 4.5E-9 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_17620 02cd2d9c30e7aa23bef11e85d05d0124 189 SUPERFAMILY SSF109604 7 181 1.43E-37 T 14-10-2018 C2I25_17620 02cd2d9c30e7aa23bef11e85d05d0124 189 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 180 4.8E-64 T 14-10-2018 IPR005249 Conserved hypothetical protein CHP00488 C2I25_00030 64881a7689d15b7be35f0264862817de 180 SUPERFAMILY SSF58064 67 130 2.39E-5 T 14-10-2018 C2I25_00030 64881a7689d15b7be35f0264862817de 180 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 3 180 18.721 T 14-10-2018 IPR023522 Chromosome-anchoring protein RacA C2I25_00030 64881a7689d15b7be35f0264862817de 180 Gene3D G3DSA:1.10.1660.10 4 67 5.3E-10 T 14-10-2018 C2I25_28505 64881a7689d15b7be35f0264862817de 180 SUPERFAMILY SSF58064 67 130 2.39E-5 T 14-10-2018 C2I25_28505 64881a7689d15b7be35f0264862817de 180 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 3 180 18.721 T 14-10-2018 IPR023522 Chromosome-anchoring protein RacA C2I25_28505 64881a7689d15b7be35f0264862817de 180 Gene3D G3DSA:1.10.1660.10 4 67 5.3E-10 T 14-10-2018 C2I25_28550 64881a7689d15b7be35f0264862817de 180 SUPERFAMILY SSF58064 67 130 2.39E-5 T 14-10-2018 C2I25_28550 64881a7689d15b7be35f0264862817de 180 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 3 180 18.721 T 14-10-2018 IPR023522 Chromosome-anchoring protein RacA C2I25_28550 64881a7689d15b7be35f0264862817de 180 Gene3D G3DSA:1.10.1660.10 4 67 5.3E-10 T 14-10-2018 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 PIRSF PIRSF000194 1 162 1.4E-61 T 14-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 SUPERFAMILY SSF53597 1 161 8.77E-60 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 PRINTS PR00070 Dihydrofolate reductase signature 14 24 1.4E-12 T 14-10-2018 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.4E-12 T 14-10-2018 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.4E-12 T 14-10-2018 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 PRINTS PR00070 Dihydrofolate reductase signature 92 106 1.4E-12 T 14-10-2018 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 Pfam PF00186 Dihydrofolate reductase 3 160 1.1E-61 T 14-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 Gene3D G3DSA:3.40.430.10 1 162 2.4E-61 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I25_00270 e4c8db113edf67ac0b72ba9ec661bbc8 162 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 14-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 3.1E-40 T 14-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 284 614 1.6E-121 T 14-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 171 252 5.7E-30 T 14-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 171 260 2.3E-17 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 Gene3D G3DSA:3.40.50.2300 158 269 2.6E-41 T 14-10-2018 C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 148 3.8E-38 T 14-10-2018 IPR002178 PTS EIIA type-2 domain C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 SUPERFAMILY SSF52794 169 269 3.84E-36 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 Gene3D G3DSA:3.40.930.10 1 150 7.0E-48 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I25_20945 b91db38f9fdb7715aac88562572a1e2f 618 SUPERFAMILY SSF55804 1 148 6.8E-43 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 SUPERFAMILY SSF55124 270 401 8.18E-22 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 62 125 2.7E-19 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 313 375 1.4E-16 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 393 529 4.4E-11 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 PRINTS PR00397 Sirohaem Fe-binding site signature 434 452 2.7E-8 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 PRINTS PR00397 Sirohaem Fe-binding site signature 390 408 2.7E-8 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 SUPERFAMILY SSF56014 135 293 7.33E-41 T 14-10-2018 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 SUPERFAMILY SSF55124 14 134 6.21E-30 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 Gene3D G3DSA:3.30.413.10 127 307 2.0E-138 T 14-10-2018 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 Gene3D G3DSA:3.30.413.10 389 527 1.2E-33 T 14-10-2018 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 Gene3D G3DSA:3.90.480.20 13 378 2.0E-138 T 14-10-2018 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 434 450 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 SUPERFAMILY SSF56014 388 526 3.53E-32 T 14-10-2018 C2I25_04285 63e913b40369956c9f4bd3c168b39628 540 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 135 290 6.6E-34 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 26.561 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 Pfam PF01016 Ribosomal L27 protein 10 89 5.4E-34 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 5.0E-17 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 12 36 1.8E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 62 86 1.8E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 37 61 1.8E-37 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 3.7E-39 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 Gene3D G3DSA:2.40.50.100 28 93 1.2E-25 T 14-10-2018 C2I25_17065 b64a514b5f6a2a0cda12989078f57a28 96 SUPERFAMILY SSF110324 10 91 1.6E-31 T 14-10-2018 C2I25_24165 508d739f0705189b17ebe25b4cf4ce03 171 Pfam PF00583 Acetyltransferase (GNAT) family 52 150 1.3E-9 T 14-10-2018 IPR000182 GNAT domain C2I25_24165 508d739f0705189b17ebe25b4cf4ce03 171 SUPERFAMILY SSF55729 8 159 1.73E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24165 508d739f0705189b17ebe25b4cf4ce03 171 Gene3D G3DSA:3.40.630.30 2 169 1.1E-36 T 14-10-2018 C2I25_21510 a6f7aae9bdc3c238bd4c719f254a2901 47 Pfam PF13040 Fur-regulated basic protein B 2 40 2.7E-17 T 14-10-2018 IPR025004 Transcriptional regulatory protein SenN/SenS C2I25_24555 3aaa15f520cd1b9c4c882ca6932f27ce 71 SUPERFAMILY SSF47413 1 68 9.57E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_24555 3aaa15f520cd1b9c4c882ca6932f27ce 71 SMART SM00530 6 62 2.2E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_24555 3aaa15f520cd1b9c4c882ca6932f27ce 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 1.6E-24 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_24555 3aaa15f520cd1b9c4c882ca6932f27ce 71 Gene3D G3DSA:1.10.260.40 1 71 3.2E-10 T 14-10-2018 C2I25_21260 5e472ca973ac0538829b5f56c4545573 493 Pfam PF00474 Sodium:solute symporter family 34 432 6.2E-109 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_21260 5e472ca973ac0538829b5f56c4545573 493 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 5 487 9.8E-222 T 14-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 C2I25_21260 5e472ca973ac0538829b5f56c4545573 493 Gene3D G3DSA:1.20.1730.10 22 492 5.8E-103 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I25_21260 5e472ca973ac0538829b5f56c4545573 493 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 432 5.2E-101 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 Pfam PF13183 4Fe-4S dicluster domain 309 375 2.9E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 311 322 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 Gene3D G3DSA:3.40.50.10420 131 293 2.7E-11 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 SUPERFAMILY SSF46548 280 391 3.49E-17 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 Pfam PF02589 LUD domain 71 293 3.9E-54 T 14-10-2018 IPR003741 LUD domain C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 SUPERFAMILY SSF100950 64 294 3.31E-36 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 Pfam PF11870 Domain of unknown function (DUF3390) 383 469 5.1E-22 T 14-10-2018 IPR024569 4Fe-4S binding protein, C-terminal C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 453 5.6E-206 T 14-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 C2I25_04900 65cf56b51ffcfcf8986e87a00a13a3d0 473 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 473 65.05 T 14-10-2018 IPR022825 Lactate utilization protein B C2I25_18310 4637914c01120bf1f6d2955da21b8fe6 306 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 56 297 4.0E-139 T 14-10-2018 IPR010787 Protein of unknown function DUF1385 C2I25_18310 4637914c01120bf1f6d2955da21b8fe6 306 Pfam PF07136 Protein of unknown function (DUF1385) 56 300 8.0E-79 T 14-10-2018 IPR010787 Protein of unknown function DUF1385 C2I25_27995 bad0bc89b067bfeed6395631e20b6910 220 Gene3D G3DSA:3.60.15.10 4 219 1.6E-42 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_27995 bad0bc89b067bfeed6395631e20b6910 220 Pfam PF00753 Metallo-beta-lactamase superfamily 22 202 6.7E-24 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_27995 bad0bc89b067bfeed6395631e20b6910 220 SMART SM00849 18 202 2.1E-29 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_27995 bad0bc89b067bfeed6395631e20b6910 220 SUPERFAMILY SSF56281 2 211 9.43E-44 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_03420 90136716aa85b406f983801efa965f0e 5017 SUPERFAMILY SSF49401 3407 3508 1.14E-5 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 752 804 2.4E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1542 1594 2.0E-15 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 488 540 2.9E-19 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2871 2922 8.0E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1674 1726 3.1E-19 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4450 4501 1.2E-16 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 883 935 1.6E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3003 3054 9.7E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3137 3189 1.0E-19 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2215 2267 5.3E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4582 4634 5.5E-13 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1806 1857 8.5E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1014 1066 9.1E-15 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1954 1993 6.9E-12 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2607 2659 2.5E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3533 3584 7.9E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 620 671 4.1E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2347 2399 3.3E-20 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4853 4904 1.7E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4193 4245 3.3E-16 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2083 2134 9.4E-20 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4721 4772 3.3E-14 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 356 408 1.7E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3271 3321 4.2E-13 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3929 3981 6.6E-16 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4061 4112 2.3E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1410 1461 3.4E-19 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1278 1330 3.3E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4326 4370 4.6E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3401 3453 1.4E-15 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3797 3849 2.0E-15 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2479 2531 4.1E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2739 2790 2.8E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3665 3717 3.4E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1146 1197 3.4E-16 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Gene3D G3DSA:2.60.40.740 3127 3272 7.8E-6 T 14-10-2018 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Gene3D G3DSA:2.60.40.740 2076 2210 1.0E-6 T 14-10-2018 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Gene3D G3DSA:2.60.40.740 1528 1665 4.4E-6 T 14-10-2018 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 SUPERFAMILY SSF49401 4592 4683 2.39E-6 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 2611 2694 1.0E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 2346 2440 8.9E-12 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 3797 3890 4.5E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 3272 3359 7.7E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 619 710 1.1E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 1144 1233 2.1E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 3402 3484 5.2E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 2870 2954 6.3E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 1805 1893 3.7E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 4851 4949 9.0E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 4193 4286 1.6E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 2479 2566 5.5E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 750 844 8.8E-14 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 2738 2823 2.5E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 1672 1761 2.4E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 1013 1102 5.9E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 487 576 9.8E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 3136 3232 1.9E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 3006 3088 3.9E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 2083 2167 8.8E-13 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 1278 1365 1.5E-6 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 3663 3755 6.1E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 355 450 1.1E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 1409 1497 7.2E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 1541 1636 1.9E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 2214 2299 1.7E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 881 968 4.7E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 4719 4811 8.4E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 3533 3620 5.3E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 4582 4675 7.5E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 Pfam PF01345 Domain of unknown function DUF11 4450 4545 8.2E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_03420 90136716aa85b406f983801efa965f0e 5017 SUPERFAMILY SSF49401 3146 3237 5.22E-5 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 566 666 3.7E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 SMART SM00388 457 522 1.6E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 Gene3D G3DSA:3.30.450.20 332 442 3.9E-19 T 14-10-2018 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 SUPERFAMILY SSF47384 454 516 3.34E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 Gene3D G3DSA:3.30.565.10 522 672 7.4E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 SUPERFAMILY SSF55781 6 189 4.58E-21 T 14-10-2018 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 SUPERFAMILY SSF55781 261 322 7.85E-5 T 14-10-2018 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 Pfam PF13185 GAF domain 23 164 1.8E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 SMART SM00065 24 173 4.5E-14 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 615 1.3E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 629 1.3E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 648 1.3E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 Gene3D G3DSA:3.30.450.40 3 175 1.4E-23 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 SUPERFAMILY SSF55874 519 665 2.88E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 Gene3D G3DSA:1.10.287.130 460 517 7.6E-17 T 14-10-2018 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 SMART SM00387 563 669 5.0E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 Gene3D G3DSA:3.30.450.40 180 324 4.8E-7 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 Pfam PF00512 His Kinase A (phospho-acceptor) domain 459 516 5.1E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_11820 14dfa7a0c34dd403131bb37790a42602 672 SUPERFAMILY SSF55785 348 451 6.98E-12 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_14455 7b4213be46ecbe6dc4a122133f312801 187 SUPERFAMILY SSF55729 10 186 2.41E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_14455 7b4213be46ecbe6dc4a122133f312801 187 Gene3D G3DSA:3.40.630.30 7 186 1.1E-39 T 14-10-2018 C2I25_14455 7b4213be46ecbe6dc4a122133f312801 187 Pfam PF13302 Acetyltransferase (GNAT) domain 16 160 8.9E-23 T 14-10-2018 IPR000182 GNAT domain C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 Pfam PF02779 Transketolase, pyrimidine binding domain 352 523 1.1E-46 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 SUPERFAMILY SSF52922 531 663 3.8E-38 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 SUPERFAMILY SSF52518 6 324 3.17E-115 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 336 5.9E-147 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 Gene3D G3DSA:3.40.50.970 335 536 1.6E-75 T 14-10-2018 C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 Pfam PF02780 Transketolase, C-terminal domain 546 654 4.9E-12 T 14-10-2018 IPR033248 Transketolase, C-terminal domain C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 SMART SM00861 353 524 6.2E-70 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 Gene3D G3DSA:3.40.50.920 537 659 9.8E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 663 3.4E-275 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 SUPERFAMILY SSF52518 345 525 3.65E-68 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_22915 8c63a4fa259cd0761e4f682533182388 664 Gene3D G3DSA:3.40.50.970 1 334 3.5E-128 T 14-10-2018 C2I25_24200 0ffcd7671eb169d6fdc8f9d833fe74d2 235 Pfam PF12840 Helix-turn-helix domain 10 68 2.3E-10 T 14-10-2018 C2I25_24200 0ffcd7671eb169d6fdc8f9d833fe74d2 235 Gene3D G3DSA:1.10.10.10 3 90 6.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24200 0ffcd7671eb169d6fdc8f9d833fe74d2 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 7.1E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_24200 0ffcd7671eb169d6fdc8f9d833fe74d2 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 7.1E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_24200 0ffcd7671eb169d6fdc8f9d833fe74d2 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 7.1E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_24200 0ffcd7671eb169d6fdc8f9d833fe74d2 235 SUPERFAMILY SSF46785 5 86 1.84E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_24200 0ffcd7671eb169d6fdc8f9d833fe74d2 235 SMART SM00418 9 88 1.4E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_01305 88f5d1fa0129bd4e8a886d238811d9ee 148 SUPERFAMILY SSF55811 2 132 5.42E-17 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_01305 88f5d1fa0129bd4e8a886d238811d9ee 148 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_01305 88f5d1fa0129bd4e8a886d238811d9ee 148 Gene3D G3DSA:3.90.79.10 5 146 5.8E-17 T 14-10-2018 C2I25_01305 88f5d1fa0129bd4e8a886d238811d9ee 148 PRINTS PR00502 NUDIX hydrolase family signature 36 50 8.9E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_01305 88f5d1fa0129bd4e8a886d238811d9ee 148 PRINTS PR00502 NUDIX hydrolase family signature 50 65 8.9E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_01305 88f5d1fa0129bd4e8a886d238811d9ee 148 Pfam PF00293 NUDIX domain 6 139 5.9E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 Pfam PF00204 DNA gyrase B 222 392 1.7E-58 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 Gene3D G3DSA:3.30.230.10 221 402 1.9E-73 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 Pfam PF01751 Toprim domain 423 523 5.5E-16 T 14-10-2018 IPR006171 TOPRIM domain C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 SUPERFAMILY SSF55874 7 219 4.06E-69 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 72 85 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 114 128 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 572 588 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 424 438 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 508 525 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 528 540 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 37 52 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 490 506 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 268 281 2.2E-69 T 14-10-2018 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 Gene3D G3DSA:3.30.565.10 5 220 1.2E-86 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 SUPERFAMILY SSF56719 398 633 4.71E-86 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 SMART SM00387 33 177 2.0E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 6 638 48.571 T 14-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 Gene3D G3DSA:3.40.50.670 410 642 1.2E-101 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 SUPERFAMILY SSF54211 222 392 8.54E-55 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 176 1.1E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 SMART SM00433 37 633 0.0 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 568 629 7.6E-30 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 474 483 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 609 625 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 376 396 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 182 197 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 593 605 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 8 18 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 362 376 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 221 243 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 312 328 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 197 210 1.9E-60 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 7 642 0.0 T 14-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I25_21570 f0f73b61d2ef69659be88254cce11fc7 654 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 632 1.4E-266 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I25_02365 78e8a32bef9b0f0aa8fd9dea1badedb7 229 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 225 1.4E-39 T 14-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_02365 78e8a32bef9b0f0aa8fd9dea1badedb7 229 Pfam PF01048 Phosphorylase superfamily 3 224 7.8E-39 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I25_02365 78e8a32bef9b0f0aa8fd9dea1badedb7 229 SUPERFAMILY SSF53167 1 227 1.44E-51 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I25_02365 78e8a32bef9b0f0aa8fd9dea1badedb7 229 Gene3D G3DSA:3.40.50.1580 2 227 8.3E-54 T 14-10-2018 C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 3.6E-31 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 SUPERFAMILY SSF63867 338 412 1.01E-16 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 176 5.0E-39 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 SUPERFAMILY SSF53218 186 331 3.4E-38 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 SUPERFAMILY SSF63882 8 184 7.19E-51 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 SMART SM00852 189 327 1.7E-35 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 Gene3D G3DSA:2.170.190.11 50 150 5.2E-115 T 14-10-2018 C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 Pfam PF00994 Probable molybdopterin binding domain 189 325 8.6E-24 T 14-10-2018 IPR001453 MoaB/Mog domain C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 Gene3D G3DSA:3.90.105.10 26 183 5.2E-115 T 14-10-2018 C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 Gene3D G3DSA:3.40.980.10 184 336 5.2E-115 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 Pfam PF03454 MoeA C-terminal region (domain IV) 341 411 8.3E-18 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_01020 471ec9b57afb6f071c32d5cfe262c554 429 Gene3D G3DSA:2.40.340.10 337 405 5.2E-115 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_05980 b14b6d5fe82b44bbdabe50e170ec2e41 169 SUPERFAMILY SSF55729 1 165 9.29E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_05980 b14b6d5fe82b44bbdabe50e170ec2e41 169 Gene3D G3DSA:3.40.630.30 1 168 1.6E-36 T 14-10-2018 C2I25_05980 b14b6d5fe82b44bbdabe50e170ec2e41 169 Pfam PF00583 Acetyltransferase (GNAT) family 45 141 7.7E-17 T 14-10-2018 IPR000182 GNAT domain C2I25_25365 25a9408677f16336a6bb45bfa8b7aab3 254 Pfam PF08876 Domain of unknown function (DUF1836) 70 166 3.4E-16 T 14-10-2018 IPR014975 Protein of unknown function DUF1836 C2I25_14035 53b0199956f1a8e4ef9573884e0bb697 279 SUPERFAMILY SSF56601 7 277 1.25E-52 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_14035 53b0199956f1a8e4ef9573884e0bb697 279 Gene3D G3DSA:3.40.710.10 19 279 7.4E-70 T 14-10-2018 C2I25_14035 53b0199956f1a8e4ef9573884e0bb697 279 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 257 5.9E-46 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_14035 53b0199956f1a8e4ef9573884e0bb697 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 155 1.6E-8 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_14035 53b0199956f1a8e4ef9573884e0bb697 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 132 1.6E-8 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_14035 53b0199956f1a8e4ef9573884e0bb697 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 1.6E-8 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_23085 2b563e549aaf1d0365e6bec0a6a9d265 187 SMART SM01266 5 59 2.3E-18 T 14-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 C2I25_23085 2b563e549aaf1d0365e6bec0a6a9d265 187 Gene3D G3DSA:2.160.10.10 1 187 8.6E-76 T 14-10-2018 C2I25_23085 2b563e549aaf1d0365e6bec0a6a9d265 187 Pfam PF12464 Maltose acetyltransferase 7 56 2.3E-14 T 14-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 C2I25_23085 2b563e549aaf1d0365e6bec0a6a9d265 187 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 140 168 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I25_23085 2b563e549aaf1d0365e6bec0a6a9d265 187 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 131 166 1.4E-9 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_23085 2b563e549aaf1d0365e6bec0a6a9d265 187 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 87 111 0.16 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_23085 2b563e549aaf1d0365e6bec0a6a9d265 187 SUPERFAMILY SSF51161 1 185 1.8E-53 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_17220 b11f5cb687dafe438f718284214b1fa5 297 Gene3D G3DSA:1.20.1510.10 12 213 6.0E-62 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I25_17220 b11f5cb687dafe438f718284214b1fa5 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 218 294 2.6E-17 T 14-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain C2I25_17220 b11f5cb687dafe438f718284214b1fa5 297 Gene3D G3DSA:3.30.70.1350 222 293 1.1E-14 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I25_17220 b11f5cb687dafe438f718284214b1fa5 297 SUPERFAMILY SSF160240 218 295 6.54E-17 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I25_17220 b11f5cb687dafe438f718284214b1fa5 297 SUPERFAMILY SSF161111 7 214 9.94E-53 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I25_17220 b11f5cb687dafe438f718284214b1fa5 297 Pfam PF01545 Cation efflux family 15 209 3.3E-45 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I25_17220 b11f5cb687dafe438f718284214b1fa5 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 294 1.2E-74 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I25_04705 6598dcbb746d500992b5ed75c0da0855 163 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 34 158 3.2E-35 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 C2I25_04705 6598dcbb746d500992b5ed75c0da0855 163 SUPERFAMILY SSF55620 29 158 2.33E-37 T 14-10-2018 C2I25_04705 6598dcbb746d500992b5ed75c0da0855 163 Gene3D G3DSA:3.30.479.10 104 162 1.3E-9 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 C2I25_04705 6598dcbb746d500992b5ed75c0da0855 163 Gene3D G3DSA:3.30.479.10 29 103 5.8E-23 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 C2I25_04705 6598dcbb746d500992b5ed75c0da0855 163 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 34 123 2.0E-30 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 C2I25_17880 1f5bf3fe687c8188aeaa96d292445087 277 SUPERFAMILY SSF81345 3 267 1.01E-37 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_17880 1f5bf3fe687c8188aeaa96d292445087 277 Pfam PF00950 ABC 3 transport family 7 270 5.4E-64 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 C2I25_17880 1f5bf3fe687c8188aeaa96d292445087 277 Gene3D G3DSA:1.10.3470.10 38 276 5.1E-10 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_02485 4b1a7b4880745a9c1afbe3d3be1450b3 275 Pfam PF13228 Domain of unknown function (DUF4037) 115 210 4.1E-13 T 14-10-2018 IPR025117 Domain of unknown function DUF4037 C2I25_02485 4b1a7b4880745a9c1afbe3d3be1450b3 275 Gene3D G3DSA:3.30.460.10 5 130 4.1E-11 T 14-10-2018 C2I25_02485 4b1a7b4880745a9c1afbe3d3be1450b3 275 SUPERFAMILY SSF81301 9 82 8.18E-9 T 14-10-2018 C2I25_12880 9266f1283a555d5df79757d4d5341e1c 223 SMART SM00862 148 221 8.7E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_12880 9266f1283a555d5df79757d4d5341e1c 223 Gene3D G3DSA:1.10.10.10 129 223 5.5E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_12880 9266f1283a555d5df79757d4d5341e1c 223 SUPERFAMILY SSF52172 1 175 5.12E-41 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_12880 9266f1283a555d5df79757d4d5341e1c 223 Pfam PF00072 Response regulator receiver domain 3 111 7.1E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12880 9266f1283a555d5df79757d4d5341e1c 223 SMART SM00448 1 111 7.8E-45 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12880 9266f1283a555d5df79757d4d5341e1c 223 Gene3D G3DSA:3.40.50.2300 1 128 9.3E-38 T 14-10-2018 C2I25_12880 9266f1283a555d5df79757d4d5341e1c 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 4.6E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_17130 69ce5cc23ccf6183d3bc2e8c91163efe 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 273 3.6E-63 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 C2I25_17130 69ce5cc23ccf6183d3bc2e8c91163efe 277 Gene3D G3DSA:3.20.20.70 123 265 5.7E-104 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_17130 69ce5cc23ccf6183d3bc2e8c91163efe 277 PIRSF PIRSF006250 1 277 4.0E-97 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 C2I25_17130 69ce5cc23ccf6183d3bc2e8c91163efe 277 SUPERFAMILY SSF54675 2 108 3.3E-29 T 14-10-2018 C2I25_17130 69ce5cc23ccf6183d3bc2e8c91163efe 277 SUPERFAMILY SSF51690 109 275 5.1E-59 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 C2I25_17130 69ce5cc23ccf6183d3bc2e8c91163efe 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 107 4.3E-25 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 C2I25_17130 69ce5cc23ccf6183d3bc2e8c91163efe 277 Gene3D G3DSA:3.90.1170.20 14 272 5.7E-104 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 C2I25_17130 69ce5cc23ccf6183d3bc2e8c91163efe 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 275 1.1E-101 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 C2I25_20460 2f3d653a796a23fc91c76db9a022e54f 118 Pfam PF02033 Ribosome-binding factor A 4 107 3.7E-35 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 C2I25_20460 2f3d653a796a23fc91c76db9a022e54f 118 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 107 28.378 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 C2I25_20460 2f3d653a796a23fc91c76db9a022e54f 118 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 14-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 C2I25_20460 2f3d653a796a23fc91c76db9a022e54f 118 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 3.0E-44 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 C2I25_20460 2f3d653a796a23fc91c76db9a022e54f 118 Gene3D G3DSA:3.30.300.20 1 115 9.1E-41 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_20460 2f3d653a796a23fc91c76db9a022e54f 118 SUPERFAMILY SSF89919 3 110 3.14E-37 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily C2I25_20460 2f3d653a796a23fc91c76db9a022e54f 118 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 7.0E-44 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 C2I25_23840 d5ac962f5322832b605eefa08e01973b 404 Gene3D G3DSA:3.30.70.360 175 292 3.6E-137 T 14-10-2018 C2I25_23840 d5ac962f5322832b605eefa08e01973b 404 SUPERFAMILY SSF55031 178 283 1.2E-23 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_23840 d5ac962f5322832b605eefa08e01973b 404 PIRSF PIRSF037226 3 402 3.2E-177 T 14-10-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted C2I25_23840 d5ac962f5322832b605eefa08e01973b 404 Pfam PF01546 Peptidase family M20/M25/M40 89 354 3.6E-9 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_23840 d5ac962f5322832b605eefa08e01973b 404 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 349 2.8E-71 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_23840 d5ac962f5322832b605eefa08e01973b 404 Gene3D G3DSA:3.40.630.10 26 370 3.6E-137 T 14-10-2018 C2I25_23840 d5ac962f5322832b605eefa08e01973b 404 Pfam PF07687 Peptidase dimerisation domain 182 269 5.0E-8 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_23840 d5ac962f5322832b605eefa08e01973b 404 SUPERFAMILY SSF53187 11 384 3.64E-60 T 14-10-2018 C2I25_24900 a8964fffbf252b1bf4112384dad46dce 166 Pfam PF13420 Acetyltransferase (GNAT) domain 2 158 8.6E-23 T 14-10-2018 C2I25_24900 a8964fffbf252b1bf4112384dad46dce 166 SUPERFAMILY SSF55729 1 164 8.97E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24900 a8964fffbf252b1bf4112384dad46dce 166 Gene3D G3DSA:3.40.630.30 1 165 1.0E-44 T 14-10-2018 C2I25_22900 efc3f593c8bd20138770a6f53d116acf 317 Pfam PF13602 Zinc-binding dehydrogenase 187 313 6.4E-23 T 14-10-2018 C2I25_22900 efc3f593c8bd20138770a6f53d116acf 317 SMART SM00829 10 313 5.4E-26 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_22900 efc3f593c8bd20138770a6f53d116acf 317 Gene3D G3DSA:3.40.50.720 128 262 2.1E-101 T 14-10-2018 C2I25_22900 efc3f593c8bd20138770a6f53d116acf 317 SUPERFAMILY SSF50129 1 150 1.35E-41 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_22900 efc3f593c8bd20138770a6f53d116acf 317 SUPERFAMILY SSF51735 117 244 7.77E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22900 efc3f593c8bd20138770a6f53d116acf 317 Gene3D G3DSA:3.90.180.10 8 312 2.1E-101 T 14-10-2018 C2I25_22900 efc3f593c8bd20138770a6f53d116acf 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 2.8E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_01230 9bc2f7638764595605258566eb17cddf 402 Gene3D G3DSA:3.40.50.2000 216 379 1.4E-127 T 14-10-2018 C2I25_01230 9bc2f7638764595605258566eb17cddf 402 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 7 394 3.9E-121 T 14-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 C2I25_01230 9bc2f7638764595605258566eb17cddf 402 Gene3D G3DSA:3.40.50.2000 5 390 1.4E-127 T 14-10-2018 C2I25_01230 9bc2f7638764595605258566eb17cddf 402 SUPERFAMILY SSF53756 1 392 5.8E-82 T 14-10-2018 C2I25_01230 9bc2f7638764595605258566eb17cddf 402 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 230 371 2.1E-24 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 C2I25_24875 635584099f108aeca37a2a6146cca399 129 Gene3D G3DSA:3.10.180.10 2 129 5.1E-52 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24875 635584099f108aeca37a2a6146cca399 129 SUPERFAMILY SSF54593 6 125 2.48E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24875 635584099f108aeca37a2a6146cca399 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 122 2.4E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_06035 2663bc13f7669109db036d04b579e548 450 Pfam PF13218 Protein of unknown function (DUF4026) 17 339 6.1E-162 T 14-10-2018 IPR025102 Protein of unknown function DUF4026 C2I25_06035 2663bc13f7669109db036d04b579e548 450 Pfam PF10077 Uncharacterized protein conserved in bacteria (DUF2314) 347 436 2.1E-9 T 14-10-2018 IPR018756 Domain of unknown function DUF2314 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 Gene3D G3DSA:3.20.20.10 38 297 5.7E-156 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 SUPERFAMILY SSF50621 274 431 6.7E-51 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 10 429 2.8E-153 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 Gene3D G3DSA:2.40.37.10 17 427 5.7E-156 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 1.6E-25 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 1.6E-25 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 1.6E-25 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 1.6E-25 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 39.573 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 297 5.3E-66 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 3.9E-15 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 3.9E-15 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 3.9E-15 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 3.9E-15 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 SUPERFAMILY SSF51419 30 299 4.94E-83 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_04310 3222bbeb7a8bd2ee25bcf3be6354ced6 438 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 34 388 8.3E-16 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 C2I25_11030 a8b7f44ad6c48ade403a9e0f8e205173 166 SUPERFAMILY SSF160369 5 160 1.22E-54 T 14-10-2018 C2I25_11030 a8b7f44ad6c48ade403a9e0f8e205173 166 Gene3D G3DSA:3.30.70.1730 1 165 7.6E-43 T 14-10-2018 C2I25_11030 a8b7f44ad6c48ade403a9e0f8e205173 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 26 143 0.002 T 14-10-2018 C2I25_11030 a8b7f44ad6c48ade403a9e0f8e205173 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.24 T 14-10-2018 IPR022973 Ribosomal protein L10 C2I25_11030 a8b7f44ad6c48ade403a9e0f8e205173 166 Pfam PF00466 Ribosomal protein L10 6 100 2.0E-29 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 C2I25_11030 a8b7f44ad6c48ade403a9e0f8e205173 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 14-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_12475 0ba5ba0f4154bf6e499744b0655c057b 535 Pfam PF00117 Glutamine amidotransferase class-I 302 526 3.4E-60 T 14-10-2018 IPR017926 Glutamine amidotransferase C2I25_12475 0ba5ba0f4154bf6e499744b0655c057b 535 SUPERFAMILY SSF52540 1 269 2.01E-127 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12475 0ba5ba0f4154bf6e499744b0655c057b 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 5.9E-265 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 C2I25_12475 0ba5ba0f4154bf6e499744b0655c057b 535 Gene3D G3DSA:3.40.50.880 286 535 1.3E-102 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_12475 0ba5ba0f4154bf6e499744b0655c057b 535 Hamap MF_01227 CTP synthase [pyrG]. 2 532 53.019 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 C2I25_12475 0ba5ba0f4154bf6e499744b0655c057b 535 Pfam PF06418 CTP synthase N-terminus 3 267 4.2E-131 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 C2I25_12475 0ba5ba0f4154bf6e499744b0655c057b 535 Gene3D G3DSA:3.40.50.300 1 285 1.0E-135 T 14-10-2018 C2I25_12475 0ba5ba0f4154bf6e499744b0655c057b 535 SUPERFAMILY SSF52317 289 533 5.77E-84 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_22045 c463c4876d86b743a871d9b8de564333 249 Pfam PF00483 Nucleotidyl transferase 2 241 1.9E-15 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_22045 c463c4876d86b743a871d9b8de564333 249 Gene3D G3DSA:3.90.550.10 1 248 5.7E-63 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_22045 c463c4876d86b743a871d9b8de564333 249 SUPERFAMILY SSF53448 1 245 1.1E-56 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_22840 5429f6258089e29097e198cc088c9a6b 199 SUPERFAMILY SSF55469 4 198 2.22E-72 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_22840 5429f6258089e29097e198cc088c9a6b 199 Pfam PF00881 Nitroreductase family 10 177 7.5E-17 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_22840 5429f6258089e29097e198cc088c9a6b 199 Gene3D G3DSA:3.40.109.10 2 199 8.4E-91 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_11100 e9c346f1d96f7ae4e68e5335e7576e5e 226 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 221 44.822 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 C2I25_11100 e9c346f1d96f7ae4e68e5335e7576e5e 226 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 99 106 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 C2I25_11100 e9c346f1d96f7ae4e68e5335e7576e5e 226 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 221 4.1E-78 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 C2I25_11100 e9c346f1d96f7ae4e68e5335e7576e5e 226 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 220 2.5E-77 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 C2I25_11100 e9c346f1d96f7ae4e68e5335e7576e5e 226 Gene3D G3DSA:3.90.550.10 1 224 9.3E-83 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_11100 e9c346f1d96f7ae4e68e5335e7576e5e 226 SUPERFAMILY SSF53448 2 221 4.96E-62 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 84 182 8.2E-21 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 219 355 3.3E-29 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 465 559 2.3E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 584 701 1.5E-36 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 523 4.1E-43 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 544 4.1E-43 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 638 650 4.1E-43 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 633 4.1E-43 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 162 176 4.1E-43 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 329 343 4.1E-43 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 SUPERFAMILY SSF81653 115 228 3.92E-30 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 SMART SM00831 3 77 1.4E-27 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 Pfam PF00689 Cation transporting ATPase, C-terminus 699 885 2.5E-51 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 Gene3D G3DSA:2.70.150.10 16 232 0.0 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 249 271 1.0E-8 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 322 343 1.0E-8 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 SUPERFAMILY SSF81660 336 516 3.92E-53 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 SUPERFAMILY SSF81665 2 887 2.09E-137 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 SUPERFAMILY SSF56784 327 718 7.42E-64 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 Gene3D G3DSA:1.20.1110.10 55 884 0.0 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 72 5.4E-20 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 Gene3D G3DSA:3.40.1110.10 339 519 0.0 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 Gene3D G3DSA:3.40.50.1000 326 659 0.0 T 14-10-2018 IPR023214 HAD superfamily C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 Pfam PF00122 E1-E2 ATPase 112 309 1.3E-55 T 14-10-2018 C2I25_09275 dea0a2f7578b497d8d962ea8946268db 888 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 628 8.9E-24 T 14-10-2018 C2I25_12895 61167514a9d28e96124fe091edc7e4ab 344 Gene3D G3DSA:3.40.190.10 45 313 3.6E-68 T 14-10-2018 C2I25_12895 61167514a9d28e96124fe091edc7e4ab 344 SUPERFAMILY SSF53850 42 307 5.55E-49 T 14-10-2018 C2I25_12895 61167514a9d28e96124fe091edc7e4ab 344 Gene3D G3DSA:3.40.190.10 142 262 3.6E-68 T 14-10-2018 C2I25_12895 61167514a9d28e96124fe091edc7e4ab 344 Pfam PF13343 Bacterial extracellular solute-binding protein 88 329 4.5E-50 T 14-10-2018 C2I25_27160 f1f64f53abeb60809c3d0f60875955e2 241 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_27160 f1f64f53abeb60809c3d0f60875955e2 241 Pfam PF00005 ABC transporter 21 162 3.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_27160 f1f64f53abeb60809c3d0f60875955e2 241 Gene3D G3DSA:3.40.50.300 1 237 4.5E-66 T 14-10-2018 C2I25_27160 f1f64f53abeb60809c3d0f60875955e2 241 SUPERFAMILY SSF52540 4 223 6.23E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_27160 f1f64f53abeb60809c3d0f60875955e2 241 SMART SM00382 30 209 6.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_27395 5be2b4308e27b948d0cb2eccb7ecb785 240 Gene3D G3DSA:3.40.50.1820 3 237 2.5E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_27395 5be2b4308e27b948d0cb2eccb7ecb785 240 Pfam PF00975 Thioesterase domain 5 230 7.2E-46 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 C2I25_27395 5be2b4308e27b948d0cb2eccb7ecb785 240 SUPERFAMILY SSF53474 3 230 9.59E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_20250 7f8175ad5991be7833d8788de5338cc6 314 SUPERFAMILY SSF52151 4 307 7.06E-80 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I25_20250 7f8175ad5991be7833d8788de5338cc6 314 PIRSF PIRSF000446 1 311 1.6E-116 T 14-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 C2I25_20250 7f8175ad5991be7833d8788de5338cc6 314 Pfam PF00698 Acyl transferase domain 6 282 9.7E-43 T 14-10-2018 IPR014043 Acyl transferase C2I25_20250 7f8175ad5991be7833d8788de5338cc6 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 9.8E-53 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain C2I25_20250 7f8175ad5991be7833d8788de5338cc6 314 SUPERFAMILY SSF55048 128 193 4.19E-14 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding C2I25_20250 7f8175ad5991be7833d8788de5338cc6 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 1.8E-112 T 14-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 C2I25_20250 7f8175ad5991be7833d8788de5338cc6 314 Gene3D G3DSA:3.40.366.10 6 285 2.5E-98 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 C2I25_20250 7f8175ad5991be7833d8788de5338cc6 314 Gene3D G3DSA:3.30.70.250 126 199 2.5E-98 T 14-10-2018 C2I25_15500 dd23050a6cdf0b6a5d9f2e366f0e9e59 190 Gene3D G3DSA:3.40.50.150 1 190 9.1E-70 T 14-10-2018 C2I25_15500 dd23050a6cdf0b6a5d9f2e366f0e9e59 190 Pfam PF06962 Putative rRNA methylase 48 188 2.0E-50 T 14-10-2018 IPR010719 Putative rRNA methylase C2I25_15500 dd23050a6cdf0b6a5d9f2e366f0e9e59 190 SUPERFAMILY SSF53335 12 163 1.57E-21 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_05195 ea084f4c10457a5b888fe0f29339616d 258 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 46 59 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I25_05195 ea084f4c10457a5b888fe0f29339616d 258 SUPERFAMILY SSF51366 6 250 3.77E-84 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I25_05195 ea084f4c10457a5b888fe0f29339616d 258 Gene3D G3DSA:3.20.20.70 3 257 2.2E-94 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_05195 ea084f4c10457a5b888fe0f29339616d 258 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 11 244 4.4E-78 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I25_05195 ea084f4c10457a5b888fe0f29339616d 258 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 11 255 33.612 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I25_05195 ea084f4c10457a5b888fe0f29339616d 258 Pfam PF00290 Tryptophan synthase alpha chain 10 249 6.6E-90 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 4.1E-72 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 PIRSF PIRSF000149 1 333 1.5E-142 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 5.1E-141 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 SUPERFAMILY SSF51735 3 167 1.28E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 6.5E-43 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 SUPERFAMILY SSF55347 151 313 4.17E-75 T 14-10-2018 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 Gene3D G3DSA:3.30.360.10 150 314 6.4E-161 T 14-10-2018 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 Gene3D G3DSA:3.40.50.720 3 328 6.4E-161 T 14-10-2018 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 SMART SM00846 2 151 3.6E-98 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 5.1E-40 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 5.1E-40 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 5.1E-40 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 5.1E-40 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_13530 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 5.1E-40 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 Gene3D G3DSA:3.30.70.141 1 148 4.2E-65 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 SMART SM00562 1 138 2.4E-89 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 36.505 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 Pfam PF00334 Nucleoside diphosphate kinase 2 135 3.1E-58 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 SUPERFAMILY SSF54919 1 148 6.55E-61 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 8.7E-51 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 8.7E-51 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 8.7E-51 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 8.7E-51 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 8.7E-51 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I25_03825 a804f71c0a5f5ec571cdb838e1cbee08 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 14-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I25_28215 e36685214ce7ef1c37b3525f598e36f3 79 SUPERFAMILY SSF88697 1 79 1.04E-19 T 14-10-2018 IPR015947 PUA-like superfamily C2I25_28215 e36685214ce7ef1c37b3525f598e36f3 79 Pfam PF10763 Protein of unknown function (DUF2584) 1 79 3.8E-27 T 14-10-2018 IPR019699 Protein of unknown function DUF2584 C2I25_28215 e36685214ce7ef1c37b3525f598e36f3 79 Gene3D G3DSA:2.40.240.20 1 76 3.2E-27 T 14-10-2018 C2I25_09095 d5bdc9bc920683a6bb2d8bfe4608a35a 500 Pfam PF02378 Phosphotransferase system, EIIC 9 342 5.8E-79 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_09095 d5bdc9bc920683a6bb2d8bfe4608a35a 500 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 439 456 - T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_09095 d5bdc9bc920683a6bb2d8bfe4608a35a 500 Pfam PF00367 phosphotransferase system, EIIB 430 461 3.6E-13 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_09095 d5bdc9bc920683a6bb2d8bfe4608a35a 500 Gene3D G3DSA:3.30.1360.60 426 500 3.8E-25 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_09095 d5bdc9bc920683a6bb2d8bfe4608a35a 500 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 497 4.9E-186 T 14-10-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 C2I25_09095 d5bdc9bc920683a6bb2d8bfe4608a35a 500 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 399 486 1.1E-20 T 14-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I25_09095 d5bdc9bc920683a6bb2d8bfe4608a35a 500 SUPERFAMILY SSF55604 428 499 1.01E-19 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_09280 786d8c02bf87963e27c579cd2a482fa5 360 Pfam PF05816 Toxic anion resistance protein (TelA) 31 359 2.0E-102 T 14-10-2018 IPR008863 Toxic anion resistance C2I25_09280 786d8c02bf87963e27c579cd2a482fa5 360 PIRSF PIRSF026508 1 360 3.5E-125 T 14-10-2018 IPR008863 Toxic anion resistance C2I25_13175 3129140aa6e71d2e2e9a002e4624d9d9 369 SUPERFAMILY SSF53335 93 311 8.44E-54 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_13175 3129140aa6e71d2e2e9a002e4624d9d9 369 Gene3D G3DSA:3.40.50.150 125 360 1.3E-54 T 14-10-2018 C2I25_13175 3129140aa6e71d2e2e9a002e4624d9d9 369 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 149 162 - T 14-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I25_13175 3129140aa6e71d2e2e9a002e4624d9d9 369 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 78 337 26.303 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I25_13175 3129140aa6e71d2e2e9a002e4624d9d9 369 Pfam PF01564 Spermine/spermidine synthase domain 128 302 4.9E-35 T 14-10-2018 C2I25_18765 ddda19c66ebc3de2f03ce31b56acea9a 408 Gene3D G3DSA:3.10.20.340 280 408 1.6E-48 T 14-10-2018 C2I25_18765 ddda19c66ebc3de2f03ce31b56acea9a 408 SUPERFAMILY SSF56266 18 404 9.42E-139 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I25_18765 ddda19c66ebc3de2f03ce31b56acea9a 408 Gene3D G3DSA:3.60.70.12 4 194 2.8E-69 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I25_18765 ddda19c66ebc3de2f03ce31b56acea9a 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 14 408 1.4E-153 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I25_18765 ddda19c66ebc3de2f03ce31b56acea9a 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 141.888 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I25_18765 ddda19c66ebc3de2f03ce31b56acea9a 408 Pfam PF01960 ArgJ family 25 408 4.7E-147 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I25_18765 ddda19c66ebc3de2f03ce31b56acea9a 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 35 408 0.0 T 14-10-2018 C2I25_18765 ddda19c66ebc3de2f03ce31b56acea9a 408 Gene3D G3DSA:3.30.2330.10 195 279 5.4E-32 T 14-10-2018 C2I25_21725 ff056e1bfa7fdc9313744f174df6de3c 265 Gene3D G3DSA:3.10.20.10 28 110 9.0E-14 T 14-10-2018 C2I25_21725 ff056e1bfa7fdc9313744f174df6de3c 265 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 262 32.308 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I25_21725 ff056e1bfa7fdc9313744f174df6de3c 265 Gene3D G3DSA:3.40.140.10 116 265 8.2E-48 T 14-10-2018 C2I25_21725 ff056e1bfa7fdc9313744f174df6de3c 265 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 262 6.1E-73 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I25_21725 ff056e1bfa7fdc9313744f174df6de3c 265 Pfam PF02634 FdhD/NarQ family 26 261 2.5E-80 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I25_21725 ff056e1bfa7fdc9313744f174df6de3c 265 PIRSF PIRSF015626 1 264 8.3E-80 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I25_21725 ff056e1bfa7fdc9313744f174df6de3c 265 SUPERFAMILY SSF53927 5 261 2.32E-77 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_16380 501e8242f97856d3b28b41ed776c6531 210 Pfam PF02659 Putative manganese efflux pump 127 208 2.1E-10 T 14-10-2018 IPR003810 Putative manganese efflux pump C2I25_16380 501e8242f97856d3b28b41ed776c6531 210 Pfam PF02659 Putative manganese efflux pump 6 83 6.4E-10 T 14-10-2018 IPR003810 Putative manganese efflux pump C2I25_16380 501e8242f97856d3b28b41ed776c6531 210 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 5 210 2.4E-74 T 14-10-2018 IPR014205 Sporulation protein YtaF C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 Gene3D G3DSA:1.10.287.950 381 657 4.4E-68 T 14-10-2018 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 SMART SM00283 382 657 1.4E-78 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 SUPERFAMILY SSF103190 90 186 3.92E-12 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 Pfam PF00672 HAMP domain 302 349 4.7E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 Pfam PF02743 Cache domain 42 263 1.8E-26 T 14-10-2018 IPR033479 Double Cache domain 1 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 Gene3D G3DSA:1.20.1480.50 271 359 5.0E-14 T 14-10-2018 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 Gene3D G3DSA:3.30.450.20 70 181 1.8E-37 T 14-10-2018 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 SMART SM00304 598 654 11.0 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 SMART SM00304 301 353 5.8E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 607 8.7E-46 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 Gene3D G3DSA:3.30.450.20 59 270 1.8E-37 T 14-10-2018 C2I25_08700 1b3d4d94cb4e390f6238611294f6e56e 658 SUPERFAMILY SSF58104 321 657 6.41E-74 T 14-10-2018 C2I25_12600 13629198758d8e0fab49852ea8d6ec6c 414 Pfam PF00464 Serine hydroxymethyltransferase 5 381 2.5E-180 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 C2I25_12600 13629198758d8e0fab49852ea8d6ec6c 414 SUPERFAMILY SSF53383 3 412 3.85E-184 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_12600 13629198758d8e0fab49852ea8d6ec6c 414 PIRSF PIRSF000412 2 414 6.4E-172 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 C2I25_12600 13629198758d8e0fab49852ea8d6ec6c 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 412 54.077 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 C2I25_12600 13629198758d8e0fab49852ea8d6ec6c 414 Gene3D G3DSA:3.90.1150.10 7 391 4.6E-189 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_12600 13629198758d8e0fab49852ea8d6ec6c 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 C2I25_12600 13629198758d8e0fab49852ea8d6ec6c 414 Gene3D G3DSA:3.40.640.10 34 284 4.6E-189 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_22020 35c69e9febac7d04c4a7dbc2adedd657 371 Gene3D G3DSA:1.25.40.10 3 370 1.0E-92 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_22020 35c69e9febac7d04c4a7dbc2adedd657 371 SMART SM00028 253 286 40.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_22020 35c69e9febac7d04c4a7dbc2adedd657 371 SMART SM00028 138 171 77.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_22020 35c69e9febac7d04c4a7dbc2adedd657 371 SMART SM00028 179 212 4.1 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_22020 35c69e9febac7d04c4a7dbc2adedd657 371 SMART SM00028 219 252 140.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_22020 35c69e9febac7d04c4a7dbc2adedd657 371 SUPERFAMILY SSF48452 130 272 1.52E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_04615 29596bffed30143617abfaff00396648 337 Pfam PF02517 CAAX protease self-immunity 130 213 4.7E-21 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_25000 e4085f7b859caa8ab024b605c5f59e85 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 4.3E-25 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_25000 e4085f7b859caa8ab024b605c5f59e85 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 5.0E-21 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_11725 9daf13c9dcbc67e45b3a85cba61b561b 173 SUPERFAMILY SSF50249 2 173 5.48E-58 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_11725 9daf13c9dcbc67e45b3a85cba61b561b 173 Gene3D G3DSA:2.40.50.140 1 110 3.6E-46 T 14-10-2018 C2I25_11725 9daf13c9dcbc67e45b3a85cba61b561b 173 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.567 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 C2I25_11725 9daf13c9dcbc67e45b3a85cba61b561b 173 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 173 9.4E-49 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 C2I25_11725 9daf13c9dcbc67e45b3a85cba61b561b 173 Pfam PF00436 Single-strand binding protein family 2 103 7.2E-39 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 C2I25_20325 f4f70e429d096f7bf24035f20573644e 257 Pfam PF01351 Ribonuclease HII 75 249 4.1E-35 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain C2I25_20325 f4f70e429d096f7bf24035f20573644e 257 SUPERFAMILY SSF53098 62 256 1.02E-71 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_20325 f4f70e429d096f7bf24035f20573644e 257 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 251 37.059 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 C2I25_20325 f4f70e429d096f7bf24035f20573644e 257 Gene3D G3DSA:3.30.420.10 49 257 9.1E-84 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_14500 7ff07a5f0c33757fe1b1b9afc99238b9 159 SMART SM00871 3 159 2.9E-36 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_14500 7ff07a5f0c33757fe1b1b9afc99238b9 159 SUPERFAMILY SSF55136 6 158 3.14E-24 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_14500 7ff07a5f0c33757fe1b1b9afc99238b9 159 Pfam PF14526 Integron-associated effector binding protein 7 157 2.3E-29 T 14-10-2018 IPR029441 Integron-associated effector binding protein C2I25_14500 7ff07a5f0c33757fe1b1b9afc99238b9 159 Gene3D G3DSA:3.20.80.10 1 158 7.3E-45 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_11090 4791a362ad53560b86a38260b43001dc 485 SUPERFAMILY SSF52374 4 316 1.02E-113 T 14-10-2018 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 Gene3D G3DSA:3.40.50.620 1 332 1.5E-140 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_11090 4791a362ad53560b86a38260b43001dc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 2.8E-29 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 2.8E-29 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 2.8E-29 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 2.8E-29 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 2.8E-29 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 2.5E-123 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 SUPERFAMILY SSF48163 298 483 1.01E-48 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 33.787 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 482 6.0E-190 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 C2I25_11090 4791a362ad53560b86a38260b43001dc 485 Gene3D G3DSA:1.10.10.350 390 485 6.1E-32 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 SUPERFAMILY SSF52374 6 576 1.1E-145 T 14-10-2018 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 Pfam PF08264 Anticodon-binding domain of tRNA 609 755 2.2E-45 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 SUPERFAMILY SSF50677 196 347 1.44E-64 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 SUPERFAMILY SSF47323 577 829 4.67E-79 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 Gene3D G3DSA:1.10.730.10 8 743 0.0 T 14-10-2018 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 SUPERFAMILY SSF46589 815 879 3.92E-17 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 TIGRFAM TIGR00422 valS: valine--tRNA ligase 9 862 0.0 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 PRINTS PR00986 Valyl-tRNA synthetase signature 446 467 2.2E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 2.2E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 2.2E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 2.2E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 PRINTS PR00986 Valyl-tRNA synthetase signature 478 496 2.2E-38 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 566 6.2E-224 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 Gene3D G3DSA:3.90.740.10 181 347 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 880 16.228 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 Gene3D G3DSA:1.10.287.380 808 880 2.0E-23 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 Gene3D G3DSA:3.40.50.620 28 527 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_16990 ca7b6f10388c91905a223ff05c3bab7d 881 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 815 879 4.4E-25 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 SUPERFAMILY SSF50249 3 66 4.98E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 Gene3D G3DSA:2.40.50.140 2 66 2.3E-29 T 14-10-2018 C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 PIRSF PIRSF002599 1 67 1.1E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 SMART SM00357 4 67 2.8E-31 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 14-10-2018 IPR019844 Cold-shock conserved site C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 PRINTS PR00050 Cold shock protein signature 5 20 1.0E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 PRINTS PR00050 Cold shock protein signature 25 34 1.0E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 PRINTS PR00050 Cold shock protein signature 40 58 1.0E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_27915 f6b8702516c7cd239dec56f4f2081ff6 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 1.3E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I25_26895 9bfd2514e54282cc12f50d7eb558c94b 477 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 270 6.3E-72 T 14-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal C2I25_26895 9bfd2514e54282cc12f50d7eb558c94b 477 PIRSF PIRSF000331 3 477 1.3E-125 T 14-10-2018 IPR004925 HpaB/PvcC/4-BUDH C2I25_26895 9bfd2514e54282cc12f50d7eb558c94b 477 SUPERFAMILY SSF56645 7 271 1.13E-58 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I25_26895 9bfd2514e54282cc12f50d7eb558c94b 477 Gene3D G3DSA:2.40.110.10 144 271 1.6E-37 T 14-10-2018 C2I25_26895 9bfd2514e54282cc12f50d7eb558c94b 477 Gene3D G3DSA:1.10.3140.10 1 142 9.8E-32 T 14-10-2018 C2I25_26895 9bfd2514e54282cc12f50d7eb558c94b 477 SUPERFAMILY SSF47203 261 476 2.3E-59 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I25_26895 9bfd2514e54282cc12f50d7eb558c94b 477 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 285 476 2.5E-61 T 14-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal C2I25_26895 9bfd2514e54282cc12f50d7eb558c94b 477 Gene3D G3DSA:1.20.140.10 276 477 1.4E-75 T 14-10-2018 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 Gene3D G3DSA:3.40.50.920 466 579 1.9E-30 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 574 6.8E-213 T 14-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 SUPERFAMILY SSF53323 1 221 4.32E-46 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 SUPERFAMILY SSF52922 468 576 4.19E-24 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 476 570 5.8E-12 T 14-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 449 1.4E-61 T 14-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 174 4.2E-41 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 Gene3D G3DSA:3.40.50.970 186 386 1.8E-76 T 14-10-2018 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 Gene3D G3DSA:3.40.920.10 1 185 2.0E-27 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 C2I25_20645 bfe4b62dd13d94f7f572ef7047b5dda5 585 SUPERFAMILY SSF52518 196 458 3.66E-73 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_02220 23e6deab5e1c505eb8747d4753b72d8e 315 SUPERFAMILY SSF100950 56 312 1.4E-74 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_02220 23e6deab5e1c505eb8747d4753b72d8e 315 Gene3D G3DSA:1.10.10.60 1 52 3.1E-22 T 14-10-2018 C2I25_02220 23e6deab5e1c505eb8747d4753b72d8e 315 SUPERFAMILY SSF88659 11 47 1.9E-7 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_02220 23e6deab5e1c505eb8747d4753b72d8e 315 Pfam PF04198 Putative sugar-binding domain 57 310 5.4E-77 T 14-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 C2I25_02220 23e6deab5e1c505eb8747d4753b72d8e 315 Pfam PF04545 Sigma-70, region 4 14 47 1.4E-6 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_02220 23e6deab5e1c505eb8747d4753b72d8e 315 Gene3D G3DSA:3.40.50.1360 53 311 1.8E-83 T 14-10-2018 C2I25_10855 655b431335a7bd76b1d6c7d3440f8898 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.9E-29 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 C2I25_10855 655b431335a7bd76b1d6c7d3440f8898 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.88 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 C2I25_10855 655b431335a7bd76b1d6c7d3440f8898 72 Gene3D G3DSA:2.40.50.140 1 72 6.1E-38 T 14-10-2018 C2I25_10855 655b431335a7bd76b1d6c7d3440f8898 72 SMART SM00316 4 72 6.8E-6 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_10855 655b431335a7bd76b1d6c7d3440f8898 72 SUPERFAMILY SSF50249 1 71 7.89E-29 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_10855 655b431335a7bd76b1d6c7d3440f8898 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 4.4E-39 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 Pfam PF00696 Amino acid kinase family 2 235 2.2E-47 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 58 401 3.5E-96 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 Gene3D G3DSA:3.40.1160.10 1 253 4.0E-84 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 SUPERFAMILY SSF55021 335 404 3.44E-17 T 14-10-2018 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 Gene3D G3DSA:3.30.2130.10 254 409 4.8E-36 T 14-10-2018 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 SUPERFAMILY SSF55021 260 346 7.56E-14 T 14-10-2018 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 Pfam PF13840 ACT domain 336 398 8.4E-22 T 14-10-2018 IPR027795 CASTOR, ACT domain C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 PIRSF PIRSF000726 61 409 6.4E-95 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 PIRSF PIRSF000726 1 65 4.0E-9 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.3E-139 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I25_20515 a08b83ab49cfa910e656fdda40acf418 410 SUPERFAMILY SSF53633 3 246 6.28E-68 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_24215 872e2e0d8df367355d560739b84b0243 250 SUPERFAMILY SSF46785 6 75 5.77E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_24215 872e2e0d8df367355d560739b84b0243 250 Pfam PF01614 Bacterial transcriptional regulator 120 244 2.0E-33 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal C2I25_24215 872e2e0d8df367355d560739b84b0243 250 Gene3D G3DSA:3.30.450.40 76 249 2.1E-50 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_24215 872e2e0d8df367355d560739b84b0243 250 SUPERFAMILY SSF55781 60 248 3.73E-46 T 14-10-2018 C2I25_24215 872e2e0d8df367355d560739b84b0243 250 Pfam PF09339 IclR helix-turn-helix domain 7 55 1.6E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I25_24215 872e2e0d8df367355d560739b84b0243 250 SMART SM00346 4 92 1.1E-22 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I25_24215 872e2e0d8df367355d560739b84b0243 250 Gene3D G3DSA:1.10.10.10 4 75 1.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25955 0bcd60c22d89af2d816be5d28e7792c5 225 Gene3D G3DSA:3.40.50.300 1 224 7.5E-64 T 14-10-2018 C2I25_25955 0bcd60c22d89af2d816be5d28e7792c5 225 Pfam PF00005 ABC transporter 24 170 6.3E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_25955 0bcd60c22d89af2d816be5d28e7792c5 225 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_25955 0bcd60c22d89af2d816be5d28e7792c5 225 SUPERFAMILY SSF52540 3 221 1.77E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25955 0bcd60c22d89af2d816be5d28e7792c5 225 SMART SM00382 33 219 3.8E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_22025 5446ce2c2a64a97aa954d54bd97e9da4 373 Pfam PF01385 Probable transposase 166 275 9.2E-27 T 14-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 C2I25_22025 5446ce2c2a64a97aa954d54bd97e9da4 373 Pfam PF07282 Putative transposase DNA-binding domain 289 358 1.2E-24 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal C2I25_22025 5446ce2c2a64a97aa954d54bd97e9da4 373 Pfam PF12323 Helix-turn-helix domain 2 48 1.7E-20 T 14-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain C2I25_22025 5446ce2c2a64a97aa954d54bd97e9da4 373 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 244 316 1.3E-14 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal C2I25_02370 a6d11281f68e71c14d24dbc370242fc1 307 SUPERFAMILY SSF53474 2 305 1.03E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_02370 a6d11281f68e71c14d24dbc370242fc1 307 Pfam PF12146 Serine aminopeptidase, S33 26 289 1.3E-51 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 C2I25_02370 a6d11281f68e71c14d24dbc370242fc1 307 Gene3D G3DSA:3.40.50.1820 2 306 5.5E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_08195 bb53bf341a07dfb21a555273de3d3cbe 449 ProSitePatterns PS00942 glpT family of transporters signature. 155 171 - T 14-10-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site Reactome: R-HSA-3229133|Reactome: R-HSA-70263 C2I25_08195 bb53bf341a07dfb21a555273de3d3cbe 449 Gene3D G3DSA:1.20.1250.20 244 448 8.8E-56 T 14-10-2018 C2I25_08195 bb53bf341a07dfb21a555273de3d3cbe 449 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 37 421 3.7E-155 T 14-10-2018 C2I25_08195 bb53bf341a07dfb21a555273de3d3cbe 449 SUPERFAMILY SSF103473 13 439 6.15E-80 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_08195 bb53bf341a07dfb21a555273de3d3cbe 449 Pfam PF07690 Major Facilitator Superfamily 36 403 8.0E-51 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_08195 bb53bf341a07dfb21a555273de3d3cbe 449 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 5 442 2.1E-227 T 14-10-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 C2I25_08195 bb53bf341a07dfb21a555273de3d3cbe 449 Gene3D G3DSA:1.20.1250.20 20 229 1.4E-56 T 14-10-2018 C2I25_08195 bb53bf341a07dfb21a555273de3d3cbe 449 PIRSF PIRSF002808 7 449 2.2E-164 T 14-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 Pfam PF00005 ABC transporter 21 162 2.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 Gene3D G3DSA:2.40.50.100 240 363 4.3E-35 T 14-10-2018 C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 SUPERFAMILY SSF50331 237 365 2.07E-28 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 SMART SM00382 29 212 4.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 Gene3D G3DSA:2.40.50.140 304 349 4.3E-35 T 14-10-2018 C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 Pfam PF08402 TOBE domain 282 357 6.2E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 SUPERFAMILY SSF52540 4 243 2.26E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_19400 e24f462619ecb33c40754af0a9dad2d9 366 Gene3D G3DSA:3.40.50.300 1 239 8.7E-76 T 14-10-2018 C2I25_16805 69bd8ae5f23121a754e80860d6e32b84 190 SUPERFAMILY SSF47413 12 76 1.27E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_16805 69bd8ae5f23121a754e80860d6e32b84 190 Pfam PF07883 Cupin domain 126 182 4.3E-10 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_16805 69bd8ae5f23121a754e80860d6e32b84 190 SMART SM00530 19 74 2.3E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_16805 69bd8ae5f23121a754e80860d6e32b84 190 SUPERFAMILY SSF51182 68 186 5.73E-16 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_16805 69bd8ae5f23121a754e80860d6e32b84 190 Gene3D G3DSA:2.60.120.10 98 190 1.5E-21 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_16805 69bd8ae5f23121a754e80860d6e32b84 190 Pfam PF01381 Helix-turn-helix 20 72 1.6E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_16805 69bd8ae5f23121a754e80860d6e32b84 190 Gene3D G3DSA:1.10.260.40 6 81 1.9E-18 T 14-10-2018 C2I25_12725 52a0585b04cb77c9c2bb5e9e25710dbd 500 Pfam PF00361 Proton-conducting membrane transporter 139 437 7.0E-67 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12725 52a0585b04cb77c9c2bb5e9e25710dbd 500 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 496 8.0E-136 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12725 52a0585b04cb77c9c2bb5e9e25710dbd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 254 278 7.4E-34 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12725 52a0585b04cb77c9c2bb5e9e25710dbd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 394 420 7.4E-34 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12725 52a0585b04cb77c9c2bb5e9e25710dbd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 361 7.4E-34 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12725 52a0585b04cb77c9c2bb5e9e25710dbd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 7.4E-34 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12725 52a0585b04cb77c9c2bb5e9e25710dbd 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 7.4E-34 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_10975 35868332db1e892ba7188e536bd58957 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.4E-36 T 14-10-2018 IPR027486 Ribosomal protein S10 domain C2I25_10975 35868332db1e892ba7188e536bd58957 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10975 35868332db1e892ba7188e536bd58957 102 SUPERFAMILY SSF54999 5 102 1.2E-38 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily C2I25_10975 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.3E-20 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10975 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.3E-20 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10975 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.3E-20 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10975 35868332db1e892ba7188e536bd58957 102 SMART SM01403 7 101 8.1E-60 T 14-10-2018 IPR027486 Ribosomal protein S10 domain C2I25_10975 35868332db1e892ba7188e536bd58957 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.5E-46 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10975 35868332db1e892ba7188e536bd58957 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.164 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10975 35868332db1e892ba7188e536bd58957 102 Gene3D G3DSA:3.30.70.600 1 102 5.3E-38 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily C2I25_15600 40086c1db341f44d0c4f551b190b1a55 101 SMART SM00450 7 101 5.6E-12 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_15600 40086c1db341f44d0c4f551b190b1a55 101 Gene3D G3DSA:3.40.250.10 4 100 7.1E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_15600 40086c1db341f44d0c4f551b190b1a55 101 SUPERFAMILY SSF52821 3 97 1.17E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_15600 40086c1db341f44d0c4f551b190b1a55 101 Pfam PF00581 Rhodanese-like domain 8 97 9.7E-12 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_02230 fbe54ba6d3665a712f924298d9cea602 221 Pfam PF02517 CAAX protease self-immunity 125 212 9.2E-9 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_25105 55a3063706f21e00104741aa54b2a35e 50 SUPERFAMILY SSF160059 1 48 9.81E-20 T 14-10-2018 C2I25_25105 55a3063706f21e00104741aa54b2a35e 50 Pfam PF14553 YqbF, hypothetical protein domain 7 47 7.5E-17 T 14-10-2018 IPR027926 Uncharacterised protein YqbF domain C2I25_25105 55a3063706f21e00104741aa54b2a35e 50 Gene3D G3DSA:3.40.5.20 1 46 1.2E-11 T 14-10-2018 IPR036840 YqbF domain superfamily C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 Gene3D G3DSA:3.40.50.2300 59 150 2.0E-17 T 14-10-2018 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.2E-19 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.7E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.7E-6 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 Gene3D G3DSA:3.40.50.2300 151 325 2.9E-42 T 14-10-2018 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 321 8.4E-33 T 14-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 SUPERFAMILY SSF47413 1 60 5.55E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 Gene3D G3DSA:1.10.260.40 1 58 2.5E-21 T 14-10-2018 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 14-10-2018 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 SMART SM00354 1 71 5.4E-33 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I25_10450 671561d5cfde6cea0eb9c0ba645ddc33 325 SUPERFAMILY SSF53822 61 325 5.14E-61 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_08805 dc8d91e1a6f5b670a45ba995cae82bed 106 Pfam PF13024 Protein of unknown function (DUF3884) 20 96 1.1E-28 T 14-10-2018 IPR024979 Protein of unknown function DUF3884 C2I25_24865 8158b9099b52d48fad774aeeb3628255 215 Gene3D G3DSA:3.40.50.880 1 215 1.8E-59 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_24865 8158b9099b52d48fad774aeeb3628255 215 SUPERFAMILY SSF52317 1 185 4.07E-42 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_24865 8158b9099b52d48fad774aeeb3628255 215 Pfam PF01965 DJ-1/PfpI family 2 165 1.0E-22 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 SUPERFAMILY SSF55186 100 240 1.03E-34 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 Pfam PF02272 DHHA1 domain 271 403 3.6E-12 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 SUPERFAMILY SSF50447 14 92 6.36E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 Gene3D G3DSA:3.30.980.10 97 250 7.7E-42 T 14-10-2018 C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 SMART SM00863 192 234 4.6E-9 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 Gene3D G3DSA:3.10.310.40 305 408 5.6E-12 T 14-10-2018 C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 Pfam PF01411 tRNA synthetases class II (A) 27 86 1.9E-8 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 192 232 5.5E-8 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_21445 6d8d0ae1d5d0310aa5601f8741678d1b 411 Gene3D G3DSA:2.40.30.130 12 96 2.2E-25 T 14-10-2018 C2I25_05380 0679b45c61484d8fdd0ece435f84c345 462 Pfam PF11962 Peptidase_G2, IMC autoproteolytic cleavage domain 264 452 2.1E-44 T 14-10-2018 IPR021865 Peptidase G2, IMC autoproteolytic cleavage domain C2I25_05380 0679b45c61484d8fdd0ece435f84c345 462 Gene3D G3DSA:2.150.10.10 138 285 6.5E-10 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal C2I25_05380 0679b45c61484d8fdd0ece435f84c345 462 SUPERFAMILY SSF101967 148 280 6.67E-13 T 14-10-2018 C2I25_05380 0679b45c61484d8fdd0ece435f84c345 462 Gene3D G3DSA:2.40.300.10 307 450 7.2E-47 T 14-10-2018 C2I25_05380 0679b45c61484d8fdd0ece435f84c345 462 Gene3D G3DSA:4.10.80.40 362 397 7.2E-47 T 14-10-2018 C2I25_04355 43c415d7fe70747df1c3519f23c17055 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 2.8E-114 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 C2I25_04355 43c415d7fe70747df1c3519f23c17055 252 SUPERFAMILY SSF51366 1 251 7.85E-81 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I25_04355 43c415d7fe70747df1c3519f23c17055 252 Pfam PF00977 Histidine biosynthesis protein 5 234 1.8E-90 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 C2I25_04355 43c415d7fe70747df1c3519f23c17055 252 Gene3D G3DSA:3.20.20.70 1 252 3.1E-107 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_04355 43c415d7fe70747df1c3519f23c17055 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 48.903 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 C2I25_09015 fc61422271465e4e0e57c611552db190 270 Gene3D G3DSA:1.10.10.2800 1 111 9.3E-33 T 14-10-2018 C2I25_09015 fc61422271465e4e0e57c611552db190 270 Hamap MF_01114 Regulatory protein RecX [recX]. 46 213 15.866 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 C2I25_09015 fc61422271465e4e0e57c611552db190 270 Gene3D G3DSA:1.10.10.10 215 270 2.2E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_09015 fc61422271465e4e0e57c611552db190 270 Gene3D G3DSA:1.10.10.10 158 208 2.0E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_09015 fc61422271465e4e0e57c611552db190 270 Pfam PF02631 RecX family 88 210 3.7E-26 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 C2I25_09015 fc61422271465e4e0e57c611552db190 270 Gene3D G3DSA:1.10.10.10 112 156 1.3E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 Pfam PF01225 Mur ligase family, catalytic domain 22 84 1.6E-6 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 SUPERFAMILY SSF53244 335 491 3.27E-50 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 489 35.513 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 Pfam PF08245 Mur ligase middle domain 109 315 1.4E-55 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 Pfam PF02875 Mur ligase family, glutamate ligase domain 336 421 1.7E-23 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 Gene3D G3DSA:3.40.1390.10 2 98 1.2E-27 T 14-10-2018 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 SUPERFAMILY SSF53623 100 333 8.37E-71 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 489 5.1E-160 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 107 130 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 Gene3D G3DSA:3.90.190.20 339 492 1.6E-62 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 SUPERFAMILY SSF63418 3 100 4.05E-21 T 14-10-2018 IPR035911 MurE/MurF, N-terminal C2I25_26865 42b5d5a4c0dfa6aee0a60dfd4dad9a10 492 Gene3D G3DSA:3.40.1190.10 100 338 4.1E-88 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_09160 b3fc27f3f838aef1f9e6e15eea6ea8c2 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 240 7.7E-63 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_09160 b3fc27f3f838aef1f9e6e15eea6ea8c2 245 Gene3D G3DSA:3.30.70.660 107 244 7.9E-47 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 C2I25_09160 b3fc27f3f838aef1f9e6e15eea6ea8c2 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 35.703 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_09160 b3fc27f3f838aef1f9e6e15eea6ea8c2 245 SUPERFAMILY SSF55120 1 245 5.18E-78 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_09160 b3fc27f3f838aef1f9e6e15eea6ea8c2 245 Gene3D G3DSA:3.30.70.580 1 106 1.3E-34 T 14-10-2018 C2I25_09160 b3fc27f3f838aef1f9e6e15eea6ea8c2 245 PIRSF PIRSF001430 1 245 8.7E-81 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_09160 b3fc27f3f838aef1f9e6e15eea6ea8c2 245 Pfam PF01416 tRNA pseudouridine synthase 9 105 9.2E-9 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_09160 b3fc27f3f838aef1f9e6e15eea6ea8c2 245 Pfam PF01416 tRNA pseudouridine synthase 144 245 2.1E-27 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_22290 00ad1ac0564bdc5b28fdf472054b4e5a 259 SUPERFAMILY SSF49842 141 244 2.07E-5 T 14-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I25_22290 00ad1ac0564bdc5b28fdf472054b4e5a 259 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 13 31 7.2E-7 T 14-10-2018 IPR021201 Leader peptide, exosporium C2I25_05495 d01283883b32b7815f4eed99b339f623 551 Gene3D G3DSA:3.90.76.10 77 199 3.2E-173 T 14-10-2018 C2I25_05495 d01283883b32b7815f4eed99b339f623 551 SUPERFAMILY SSF53850 40 545 3.98E-119 T 14-10-2018 C2I25_05495 d01283883b32b7815f4eed99b339f623 551 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 469 2.7E-77 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_05495 d01283883b32b7815f4eed99b339f623 551 PIRSF PIRSF002741 1 551 4.3E-99 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_05495 d01283883b32b7815f4eed99b339f623 551 Gene3D G3DSA:3.40.190.10 58 533 3.2E-173 T 14-10-2018 C2I25_05495 d01283883b32b7815f4eed99b339f623 551 Gene3D G3DSA:3.10.105.10 299 521 3.2E-173 T 14-10-2018 C2I25_01915 4631a1041896c24afb9780e05e9bec58 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 326 3.2E-104 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I25_01915 4631a1041896c24afb9780e05e9bec58 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 226 6.1E-85 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I25_01915 4631a1041896c24afb9780e05e9bec58 338 PIRSF PIRSF000267 1 338 3.4E-113 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 82 132 1.5E-11 T 14-10-2018 IPR011096 FTP domain C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 Gene3D G3DSA:1.10.390.10 385 548 1.9E-61 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 Pfam PF03413 Peptidase propeptide and YPEB domain 147 219 7.4E-12 T 14-10-2018 IPR025711 PepSY domain C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 226 380 4.7E-45 T 14-10-2018 IPR013856 Peptidase M4 domain GO:0004222 C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 371 387 4.0E-26 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 463 479 4.0E-26 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 392 403 4.0E-26 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 335 355 4.0E-26 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 383 548 1.1E-59 T 14-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 Gene3D G3DSA:3.10.170.10 225 384 5.8E-52 T 14-10-2018 C2I25_13865 3f12ed6c420a6dc12f11030055382794 549 SUPERFAMILY SSF55486 225 549 3.11E-89 T 14-10-2018 C2I25_12490 fa54b268b152e0322cdb4db51ea3c5ab 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 1.5E-105 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I25_12490 fa54b268b152e0322cdb4db51ea3c5ab 285 SUPERFAMILY SSF51569 1 285 2.78E-105 T 14-10-2018 C2I25_12490 fa54b268b152e0322cdb4db51ea3c5ab 285 Gene3D G3DSA:3.20.20.70 1 285 2.2E-115 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_12490 fa54b268b152e0322cdb4db51ea3c5ab 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 1.2E-129 T 14-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 C2I25_12490 fa54b268b152e0322cdb4db51ea3c5ab 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I25_12490 fa54b268b152e0322cdb4db51ea3c5ab 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 2.0E-113 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I25_12490 fa54b268b152e0322cdb4db51ea3c5ab 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I25_12490 fa54b268b152e0322cdb4db51ea3c5ab 285 PIRSF PIRSF001359 1 285 2.5E-125 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I25_01365 85e1d60eb3b3c2d329cc84374f6894e1 195 Gene3D G3DSA:1.10.357.10 3 190 9.3E-22 T 14-10-2018 C2I25_01365 85e1d60eb3b3c2d329cc84374f6894e1 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_01365 85e1d60eb3b3c2d329cc84374f6894e1 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 2.0E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_01365 85e1d60eb3b3c2d329cc84374f6894e1 195 SUPERFAMILY SSF46689 8 71 3.13E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_01365 85e1d60eb3b3c2d329cc84374f6894e1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 6.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_01365 85e1d60eb3b3c2d329cc84374f6894e1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 6.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 PRINTS PR00173 Glutamate-aspartate symporter signature 47 67 2.8E-51 T 14-10-2018 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 PRINTS PR00173 Glutamate-aspartate symporter signature 326 345 2.8E-51 T 14-10-2018 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 PRINTS PR00173 Glutamate-aspartate symporter signature 353 373 2.8E-51 T 14-10-2018 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 2.8E-51 T 14-10-2018 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 PRINTS PR00173 Glutamate-aspartate symporter signature 291 317 2.8E-51 T 14-10-2018 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 2.8E-51 T 14-10-2018 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 PRINTS PR00173 Glutamate-aspartate symporter signature 189 208 2.8E-51 T 14-10-2018 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 PRINTS PR00173 Glutamate-aspartate symporter signature 224 243 2.8E-51 T 14-10-2018 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 Pfam PF00375 Sodium:dicarboxylate symporter family 6 398 5.8E-132 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 Gene3D G3DSA:1.10.3860.10 1 405 1.2E-134 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_04470 e51015333f0951b2f53597dedd3b3c3a 411 SUPERFAMILY SSF118215 6 400 8.76E-120 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Pfam PF03272 Putative mucin or carbohydrate-binding module 735 852 4.4E-25 T 14-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Pfam PF03272 Putative mucin or carbohydrate-binding module 935 1054 9.4E-28 T 14-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Pfam PF03272 Putative mucin or carbohydrate-binding module 531 652 7.4E-20 T 14-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Gene3D G3DSA:2.60.40.3600 656 729 8.4E-24 T 14-10-2018 C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Gene3D G3DSA:2.60.40.3600 448 525 4.3E-32 T 14-10-2018 C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Gene3D G3DSA:2.60.40.3600 856 929 1.7E-23 T 14-10-2018 C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Gene3D G3DSA:1.10.1740.210 153 287 9.8E-51 T 14-10-2018 C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Gene3D G3DSA:1.10.390.30 288 447 2.4E-69 T 14-10-2018 C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Pfam PF17291 N-terminal domain of M60-like peptidases 68 144 1.6E-13 T 14-10-2018 IPR035423 M60-like domain, N-terminal C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 SMART SM01276 70 358 3.4E-110 T 14-10-2018 IPR031161 Peptidase family M60 domain C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 148 408 8.8E-65 T 14-10-2018 IPR031161 Peptidase family M60 domain C2I25_13760 f2e3362ae1e7e6c462e031b0986a5efb 1058 Gene3D G3DSA:2.60.120.1250 30 152 3.3E-50 T 14-10-2018 C2I25_15665 0f2b080337958ad92f442c78b7563a73 285 SUPERFAMILY SSF103481 36 137 1.2E-10 T 14-10-2018 C2I25_15665 0f2b080337958ad92f442c78b7563a73 285 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 1 284 7.2E-115 T 14-10-2018 C2I25_15665 0f2b080337958ad92f442c78b7563a73 285 Pfam PF06800 Sugar transport protein 5 282 9.5E-110 T 14-10-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 C2I25_15665 0f2b080337958ad92f442c78b7563a73 285 SUPERFAMILY SSF103481 189 271 6.8E-7 T 14-10-2018 C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 Gene3D G3DSA:1.10.10.60 6 65 5.5E-17 T 14-10-2018 C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 Gene3D G3DSA:1.10.357.10 66 188 1.3E-9 T 14-10-2018 C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 Pfam PF08360 QacR-like protein, C-terminal region 67 168 2.5E-4 T 14-10-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 SUPERFAMILY SSF46689 5 65 1.64E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.5E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.5E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 1.3E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06130 445dbaac139dfa3347420cffe642de6e 193 SUPERFAMILY SSF48498 94 191 1.6E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_23530 1ed5d02518a4858239304c46e62cb45b 419 SUPERFAMILY SSF103473 5 392 9.94E-33 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_23530 1ed5d02518a4858239304c46e62cb45b 419 Gene3D G3DSA:1.20.1250.20 3 388 6.7E-23 T 14-10-2018 C2I25_23530 1ed5d02518a4858239304c46e62cb45b 419 Pfam PF05977 Transmembrane secretion effector 4 406 8.1E-26 T 14-10-2018 IPR010290 Transmembrane secretion effector C2I25_16770 4cb4d08b16eaadea217dd144d01b99ad 262 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 8 61 2.5E-21 T 14-10-2018 IPR025713 Motility protein B, N-terminal domain C2I25_16770 4cb4d08b16eaadea217dd144d01b99ad 262 Gene3D G3DSA:3.30.1330.60 89 260 3.8E-46 T 14-10-2018 IPR036737 OmpA-like domain superfamily C2I25_16770 4cb4d08b16eaadea217dd144d01b99ad 262 SUPERFAMILY SSF103088 135 257 6.8E-29 T 14-10-2018 IPR036737 OmpA-like domain superfamily C2I25_16770 4cb4d08b16eaadea217dd144d01b99ad 262 Pfam PF00691 OmpA family 148 248 3.4E-16 T 14-10-2018 IPR006665 OmpA-like domain C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 5.2E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 5.2E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 5.2E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 Gene3D G3DSA:3.30.70.920 55 142 1.6E-14 T 14-10-2018 C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 Gene3D G3DSA:1.10.10.10 5 53 2.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 SUPERFAMILY SSF54909 71 139 4.56E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 SUPERFAMILY SSF46785 6 65 1.4E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 3.1E-14 T 14-10-2018 C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 Pfam PF01037 Lrp/AsnC ligand binding domain 79 126 1.4E-10 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I25_23845 0a35f2ccc1b1bf6d712bd0c30f3625b7 146 SMART SM00344 7 111 6.0E-30 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 Gene3D G3DSA:3.30.1490.100 250 358 5.4E-23 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 SUPERFAMILY SSF100879 249 349 4.24E-24 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 Pfam PF11799 impB/mucB/samB family C-terminal domain 249 351 1.2E-17 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 Hamap MF_01113 DNA polymerase IV [dinB]. 9 361 36.791 T 14-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 Gene3D G3DSA:3.30.70.270 12 172 5.0E-60 T 14-10-2018 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 Gene3D G3DSA:1.10.150.20 177 244 3.0E-14 T 14-10-2018 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 Pfam PF00817 impB/mucB/samB family 15 162 1.0E-49 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 SUPERFAMILY SSF56672 6 242 3.65E-79 T 14-10-2018 C2I25_18695 898ead581f530bcf60e86f1caabbdf97 412 Gene3D G3DSA:2.30.40.20 29 82 5.0E-60 T 14-10-2018 C2I25_16935 2290dd23db01d014d4093d8f06874adc 198 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 6.4E-70 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 C2I25_16935 2290dd23db01d014d4093d8f06874adc 198 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.006 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 C2I25_16935 2290dd23db01d014d4093d8f06874adc 198 SUPERFAMILY SSF52540 16 193 4.83E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16935 2290dd23db01d014d4093d8f06874adc 198 Pfam PF01926 50S ribosome-binding GTPase 25 143 3.6E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_16935 2290dd23db01d014d4093d8f06874adc 198 Gene3D G3DSA:3.40.50.300 1 198 1.8E-55 T 14-10-2018 C2I25_07050 5a7a6881b434df7e2d066c700acead3a 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_07050 5a7a6881b434df7e2d066c700acead3a 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 1.1E-22 T 14-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I25_07050 5a7a6881b434df7e2d066c700acead3a 67 Gene3D G3DSA:1.10.8.910 8 67 7.6E-31 T 14-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I25_07050 5a7a6881b434df7e2d066c700acead3a 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_19670 24449481e848fb9894bfad374df9a7a6 42 Pfam PF13790 SR1 protein 1 38 1.4E-16 T 14-10-2018 IPR025236 SR1 protein C2I25_17485 ae06b665ca824cebca93d2715680b380 285 Gene3D G3DSA:3.10.180.10 166 284 9.6E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_17485 ae06b665ca824cebca93d2715680b380 285 Gene3D G3DSA:3.10.180.10 9 135 3.5E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_17485 ae06b665ca824cebca93d2715680b380 285 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 124 2.8E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_17485 ae06b665ca824cebca93d2715680b380 285 SUPERFAMILY SSF54593 167 278 5.64E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_17485 ae06b665ca824cebca93d2715680b380 285 SUPERFAMILY SSF54593 2 156 2.55E-36 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_09755 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 2 294 1.6E-106 T 14-10-2018 IPR005218 Diacylglycerol/lipid kinase C2I25_09755 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 127 4.7E-38 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 C2I25_09755 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 SUPERFAMILY SSF111331 1 296 2.35E-89 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily C2I25_09755 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 Gene3D G3DSA:3.40.50.10330 1 130 5.2E-48 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 C2I25_09755 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 Gene3D G3DSA:2.60.200.40 131 286 6.6E-44 T 14-10-2018 C2I25_09755 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 SMART SM00046 4 126 1.3E-9 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 C2I25_07485 a1e201d3966a9176dfc5658aa9e1e902 156 Gene3D G3DSA:1.10.10.10 2 153 9.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_07485 a1e201d3966a9176dfc5658aa9e1e902 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 102 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I25_07485 a1e201d3966a9176dfc5658aa9e1e902 156 SMART SM00347 30 129 1.6E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_07485 a1e201d3966a9176dfc5658aa9e1e902 156 SUPERFAMILY SSF46785 10 140 1.92E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_07485 a1e201d3966a9176dfc5658aa9e1e902 156 Pfam PF12802 MarR family 54 93 5.6E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_07485 a1e201d3966a9176dfc5658aa9e1e902 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_07485 a1e201d3966a9176dfc5658aa9e1e902 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_07485 a1e201d3966a9176dfc5658aa9e1e902 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01505 9e8dc84a3f312288fd67778015b10756 316 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 3 183 9.8E-56 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain C2I25_01505 9e8dc84a3f312288fd67778015b10756 316 Gene3D G3DSA:3.30.1220.10 204 316 5.0E-35 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily C2I25_01505 9e8dc84a3f312288fd67778015b10756 316 SUPERFAMILY SSF52540 2 209 4.47E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01505 9e8dc84a3f312288fd67778015b10756 316 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 221 315 2.4E-22 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I25_01505 9e8dc84a3f312288fd67778015b10756 316 SMART SM00833 221 315 3.3E-8 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I25_01505 9e8dc84a3f312288fd67778015b10756 316 Gene3D G3DSA:3.40.50.300 1 202 2.8E-72 T 14-10-2018 C2I25_01505 9e8dc84a3f312288fd67778015b10756 316 SUPERFAMILY SSF90002 221 315 2.09E-25 T 14-10-2018 C2I25_21875 f30a57d323b91a83c454cbbfa126f461 147 Pfam PF00258 Flavodoxin 6 133 2.2E-28 T 14-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 C2I25_21875 f30a57d323b91a83c454cbbfa126f461 147 SUPERFAMILY SSF52218 3 146 1.27E-39 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_21875 f30a57d323b91a83c454cbbfa126f461 147 PRINTS PR00369 Flavodoxin signature 5 18 4.6E-5 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I25_21875 f30a57d323b91a83c454cbbfa126f461 147 PRINTS PR00369 Flavodoxin signature 82 92 4.6E-5 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I25_21875 f30a57d323b91a83c454cbbfa126f461 147 PRINTS PR00369 Flavodoxin signature 53 64 4.6E-5 T 14-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I25_21875 f30a57d323b91a83c454cbbfa126f461 147 TIGRFAM TIGR01753 flav_short: flavodoxin 4 143 6.0E-47 T 14-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 C2I25_21875 f30a57d323b91a83c454cbbfa126f461 147 Gene3D G3DSA:3.40.50.360 2 146 2.3E-38 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_20565 210bab35fcf445f7d45cad5e9040356b 352 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 334 3.7E-43 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I25_11265 e0e82cf061ac72b43d3cf04252d7bf1e 291 SUPERFAMILY SSF64397 2 241 4.71E-79 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 C2I25_11265 e0e82cf061ac72b43d3cf04252d7bf1e 291 PIRSF PIRSF005261 1 291 5.3E-77 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 C2I25_11265 e0e82cf061ac72b43d3cf04252d7bf1e 291 Gene3D G3DSA:3.55.30.10 2 233 2.9E-90 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 C2I25_11265 e0e82cf061ac72b43d3cf04252d7bf1e 291 Gene3D G3DSA:3.90.1280.10 234 291 4.0E-23 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 C2I25_11265 e0e82cf061ac72b43d3cf04252d7bf1e 291 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 40.754 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 C2I25_11265 e0e82cf061ac72b43d3cf04252d7bf1e 291 SUPERFAMILY SSF118352 232 290 6.15E-20 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 C2I25_11265 e0e82cf061ac72b43d3cf04252d7bf1e 291 Pfam PF01430 Hsp33 protein 3 280 8.8E-91 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 C2I25_16050 75ea2fa31084872f70f6ddb7c12983e1 380 Pfam PF00266 Aminotransferase class-V 2 364 7.6E-75 T 14-10-2018 IPR000192 Aminotransferase class V domain C2I25_16050 75ea2fa31084872f70f6ddb7c12983e1 380 PIRSF PIRSF005572 1 378 1.9E-115 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I25_16050 75ea2fa31084872f70f6ddb7c12983e1 380 SUPERFAMILY SSF53383 1 372 1.16E-100 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_16050 75ea2fa31084872f70f6ddb7c12983e1 380 Gene3D G3DSA:3.40.640.10 13 255 8.6E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_16050 75ea2fa31084872f70f6ddb7c12983e1 380 Gene3D G3DSA:3.90.1150.10 2 370 8.6E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_04370 939760690805faed529953661f51d9fb 194 Gene3D G3DSA:3.30.230.40 90 194 2.0E-37 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 C2I25_04370 939760690805faed529953661f51d9fb 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 C2I25_04370 939760690805faed529953661f51d9fb 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 40.301 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 C2I25_04370 939760690805faed529953661f51d9fb 194 SUPERFAMILY SSF54211 87 179 1.77E-35 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_04370 939760690805faed529953661f51d9fb 194 SUPERFAMILY SSF54211 2 85 1.52E-29 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_04370 939760690805faed529953661f51d9fb 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 3.9E-65 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 C2I25_04370 939760690805faed529953661f51d9fb 194 Gene3D G3DSA:3.30.230.40 1 89 5.4E-34 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 C2I25_04370 939760690805faed529953661f51d9fb 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 C2I25_20605 869251d5c04d73132cdb222c5949b76e 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 187 7.7E-63 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 C2I25_20605 869251d5c04d73132cdb222c5949b76e 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I25_20605 869251d5c04d73132cdb222c5949b76e 192 PIRSF PIRSF000847 1 192 8.1E-51 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 C2I25_20605 869251d5c04d73132cdb222c5949b76e 192 Gene3D G3DSA:1.20.120.1760 3 187 1.3E-9 T 14-10-2018 C2I25_20605 869251d5c04d73132cdb222c5949b76e 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 1.6E-17 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I25_11700 41c3b49ee3e83c3e1f995259c0439a56 198 Pfam PF06866 Protein of unknown function (DUF1256) 19 180 5.5E-65 T 14-10-2018 IPR009665 Protein of unknown function DUF1256 C2I25_11700 41c3b49ee3e83c3e1f995259c0439a56 198 SUPERFAMILY SSF53163 10 195 1.83E-55 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily C2I25_11700 41c3b49ee3e83c3e1f995259c0439a56 198 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 44 182 2.7E-69 T 14-10-2018 IPR009665 Protein of unknown function DUF1256 C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 SUPERFAMILY SSF89260 503 612 4.71E-32 T 14-10-2018 C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 534 599 1.5E-5 T 14-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 Gene3D G3DSA:3.40.50.200 168 487 4.8E-35 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 Pfam PF00082 Subtilase family 202 468 8.2E-18 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 Gene3D G3DSA:2.60.120.380 497 613 7.5E-26 T 14-10-2018 C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 422 432 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 SUPERFAMILY SSF52743 180 465 2.49E-36 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 PRINTS PR00723 Subtilisin serine protease family (S8) signature 421 437 1.6E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 1.6E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_20710 574220e3953e0fab63eebe443c5834f5 613 PRINTS PR00723 Subtilisin serine protease family (S8) signature 234 247 1.6E-8 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 SUPERFAMILY SSF53383 111 479 7.32E-89 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 1.2E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 7.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 7.2E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 Gene3D G3DSA:3.40.640.10 156 375 5.2E-106 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 SMART SM00345 20 79 5.8E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 Gene3D G3DSA:3.90.1150.10 120 478 5.2E-106 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 SUPERFAMILY SSF46785 13 83 8.19E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 Pfam PF00155 Aminotransferase class I and II 122 473 5.1E-33 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_01670 15c4cfcdfc4d79a15cb796bced797c1d 480 Gene3D G3DSA:1.10.10.10 9 80 3.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02625 a2f86c1131037db71d457eb17836a8a8 247 SUPERFAMILY SSF53633 3 237 7.72E-59 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_02625 a2f86c1131037db71d457eb17836a8a8 247 PIRSF PIRSF005650 1 247 4.7E-82 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 C2I25_02625 a2f86c1131037db71d457eb17836a8a8 247 Pfam PF00696 Amino acid kinase family 5 216 2.9E-24 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I25_02625 a2f86c1131037db71d457eb17836a8a8 247 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 4 237 1.2E-94 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 C2I25_02625 a2f86c1131037db71d457eb17836a8a8 247 Gene3D G3DSA:3.40.1160.10 1 247 5.7E-76 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_02625 a2f86c1131037db71d457eb17836a8a8 247 Hamap MF_01220_B Uridylate kinase [pyrH]. 2 237 36.834 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 C2I25_14945 02a48932dfd5cf7e4f62395337e35905 251 Gene3D G3DSA:3.20.20.70 1 251 1.7E-116 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_14945 02a48932dfd5cf7e4f62395337e35905 251 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 9 245 7.3E-119 T 14-10-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 C2I25_14945 02a48932dfd5cf7e4f62395337e35905 251 Pfam PF07071 KDGP aldolase 9 227 3.5E-106 T 14-10-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 C2I25_09270 b17dc852a81e40f240a746e3a3c4f3fa 74 Hamap MF_00829 UPF0435 protein . 6 73 20.475 T 14-10-2018 IPR009507 Protein of unknown function UPF0435 C2I25_09270 b17dc852a81e40f240a746e3a3c4f3fa 74 Pfam PF06569 Protein of unknown function (DUF1128) 3 71 8.9E-32 T 14-10-2018 IPR009507 Protein of unknown function UPF0435 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Gene3D G3DSA:3.30.1360.40 68 149 1.4E-24 T 14-10-2018 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 68 4.5E-21 T 14-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 7.0E-17 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 7.0E-17 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 7.0E-17 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 7.0E-17 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 SUPERFAMILY SSF55252 80 145 1.03E-18 T 14-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 53.441 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 147 8.2E-40 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 SUPERFAMILY SSF46785 1 70 2.04E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 127 3.0E-18 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Pfam PF02863 Arginine repressor, C-terminal domain 80 145 8.3E-22 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 C2I25_09495 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Gene3D G3DSA:1.10.10.10 1 64 7.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 Gene3D G3DSA:3.40.710.10 283 478 1.1E-110 T 14-10-2018 C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 SUPERFAMILY SSF56601 235 567 4.54E-98 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 SMART SM00740 580 638 2.9E-14 T 14-10-2018 IPR005543 PASTA domain C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 SUPERFAMILY SSF54184 584 637 2.49E-11 T 14-10-2018 C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 Gene3D G3DSA:3.30.450.330 222 560 1.1E-110 T 14-10-2018 C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 11 638 0.0 T 14-10-2018 IPR011927 Stage V sporulation protein D C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 2.4E-88 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 Gene3D G3DSA:3.90.1310.30 49 220 3.0E-45 T 14-10-2018 C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 Gene3D G3DSA:3.30.10.20 581 637 3.1E-8 T 14-10-2018 C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 SUPERFAMILY SSF56519 51 220 1.57E-43 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 Pfam PF03793 PASTA domain 584 637 1.4E-11 T 14-10-2018 IPR005543 PASTA domain C2I25_19920 b76ea556f3b66c38958f28145b07b2a5 638 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 202 4.1E-22 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_24870 20fca6406b51015e030b392978c1a924 273 SMART SM00849 75 245 2.5E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_24870 20fca6406b51015e030b392978c1a924 273 SUPERFAMILY SSF56281 58 226 4.33E-25 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_24870 20fca6406b51015e030b392978c1a924 273 Pfam PF00753 Metallo-beta-lactamase superfamily 76 228 1.5E-5 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_24870 20fca6406b51015e030b392978c1a924 273 Gene3D G3DSA:3.60.15.10 43 271 4.7E-11 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_10685 d36f412a6f6288874c6eb42288a9edd2 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 3 254 1.4E-96 T 14-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 C2I25_10685 d36f412a6f6288874c6eb42288a9edd2 273 Gene3D G3DSA:3.40.1700.10 102 254 2.3E-60 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I25_10685 d36f412a6f6288874c6eb42288a9edd2 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 236 1.5E-43 T 14-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal C2I25_10685 d36f412a6f6288874c6eb42288a9edd2 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 254 33.734 T 14-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 C2I25_10685 d36f412a6f6288874c6eb42288a9edd2 273 PIRSF PIRSF004793 3 269 1.2E-98 T 14-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 C2I25_10685 d36f412a6f6288874c6eb42288a9edd2 273 SUPERFAMILY SSF143597 40 240 7.45E-70 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 267 22.319 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 265 2.5E-67 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 265 1.5E-30 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 Gene3D G3DSA:1.10.3730.10 165 267 1.3E-30 T 14-10-2018 C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 SUPERFAMILY SSF51735 6 158 5.29E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 SUPERFAMILY SSF48179 164 265 2.72E-26 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 Gene3D G3DSA:3.40.50.720 3 164 1.2E-37 T 14-10-2018 C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 2.1E-18 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I25_10525 8312c1e7db2abb00ddb403011242be74 267 PIRSF PIRSF000193 4 267 1.2E-66 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_00095 81a97630a51d5d3fb422edfd0b035015 406 Gene3D G3DSA:3.90.550.10 1 114 2.7E-13 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_00095 81a97630a51d5d3fb422edfd0b035015 406 SUPERFAMILY SSF48452 215 340 3.7E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00095 81a97630a51d5d3fb422edfd0b035015 406 Pfam PF00535 Glycosyl transferase family 2 17 109 5.2E-8 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_00095 81a97630a51d5d3fb422edfd0b035015 406 SUPERFAMILY SSF53448 15 114 2.44E-15 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_00095 81a97630a51d5d3fb422edfd0b035015 406 Gene3D G3DSA:1.25.40.10 167 341 1.2E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.9E-84 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 2.9E-84 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.9E-84 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 2.9E-84 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.9E-84 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 2.9E-84 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.9E-84 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 SUPERFAMILY SSF51735 122 279 1.63E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 Gene3D G3DSA:3.40.50.720 6 258 2.9E-115 T 14-10-2018 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.3E-42 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.043 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 1.1E-72 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 SUPERFAMILY SSF53223 1 121 1.06E-40 T 14-10-2018 C2I25_18415 4641a267db7ab3fc4b0518fd863be48b 286 Gene3D G3DSA:3.40.50.10860 8 276 2.9E-115 T 14-10-2018 C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 Gene3D G3DSA:3.40.1360.10 77 198 3.2E-50 T 14-10-2018 C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 14-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 SUPERFAMILY SSF111304 1 198 5.23E-79 T 14-10-2018 IPR023627 Recombination protein RecR C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 Gene3D G3DSA:1.10.8.420 1 53 1.6E-20 T 14-10-2018 C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 Pfam PF13662 Toprim domain 80 171 1.5E-26 T 14-10-2018 IPR006171 TOPRIM domain C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 Pfam PF02132 RecR protein 40 78 1.3E-15 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 SMART SM00493 80 165 3.8E-18 T 14-10-2018 IPR006171 TOPRIM domain C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 110.865 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 C2I25_11510 0de2c9d36102a34005c0078a53d9d313 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 7.0E-90 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 C2I25_16735 5ff55492d2a7ae7643a61bdaded4a901 208 SUPERFAMILY SSF81343 4 203 7.85E-63 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16735 5ff55492d2a7ae7643a61bdaded4a901 208 PIRSF PIRSF000170 1 204 6.8E-105 T 14-10-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute C2I25_16735 5ff55492d2a7ae7643a61bdaded4a901 208 Gene3D G3DSA:1.20.1300.10 1 208 9.0E-48 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_16735 5ff55492d2a7ae7643a61bdaded4a901 208 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 5 200 1.7E-55 T 14-10-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit C2I25_16735 5ff55492d2a7ae7643a61bdaded4a901 208 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 91 190 1.3E-12 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_22535 a7826ed2e6792cb685491ff446bf91a6 249 Pfam PF01061 ABC-2 type transporter 5 214 1.9E-24 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 C2I25_22535 a7826ed2e6792cb685491ff446bf91a6 249 PIRSF PIRSF006648 1 249 9.0E-67 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 C2I25_15130 d4e33af70ecbdb91d82f64b9b80c69d0 229 SUPERFAMILY SSF52172 3 179 5.73E-41 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_15130 d4e33af70ecbdb91d82f64b9b80c69d0 229 SMART SM00862 152 225 1.7E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_15130 d4e33af70ecbdb91d82f64b9b80c69d0 229 Gene3D G3DSA:3.40.50.2300 1 131 1.3E-37 T 14-10-2018 C2I25_15130 d4e33af70ecbdb91d82f64b9b80c69d0 229 Gene3D G3DSA:1.10.10.10 132 228 1.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15130 d4e33af70ecbdb91d82f64b9b80c69d0 229 Pfam PF00072 Response regulator receiver domain 5 112 3.5E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_15130 d4e33af70ecbdb91d82f64b9b80c69d0 229 SMART SM00448 3 113 1.0E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_15130 d4e33af70ecbdb91d82f64b9b80c69d0 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 225 2.8E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_19730 a677d1b9bfb85063bc3213ff03d878e9 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 94 1.0E-8 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 C2I25_19730 a677d1b9bfb85063bc3213ff03d878e9 151 Gene3D G3DSA:2.30.110.10 1 149 1.4E-60 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I25_19730 a677d1b9bfb85063bc3213ff03d878e9 151 SUPERFAMILY SSF50475 6 96 3.49E-10 T 14-10-2018 C2I25_07590 415a81d01721c62a4535189986a4b504 371 Pfam PF13407 Periplasmic binding protein domain 63 316 2.4E-43 T 14-10-2018 IPR025997 Periplasmic binding protein C2I25_07590 415a81d01721c62a4535189986a4b504 371 Gene3D G3DSA:3.40.50.2300 59 324 1.7E-89 T 14-10-2018 C2I25_07590 415a81d01721c62a4535189986a4b504 371 SUPERFAMILY SSF53822 55 334 1.01E-57 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_07590 415a81d01721c62a4535189986a4b504 371 Gene3D G3DSA:3.40.50.2300 158 331 1.7E-89 T 14-10-2018 C2I25_24195 37ccbe3ce9b5e3d9dad9469e878d18fd 156 SUPERFAMILY SSF109854 9 156 4.03E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_24195 37ccbe3ce9b5e3d9dad9469e878d18fd 156 Gene3D G3DSA:1.20.120.450 4 147 1.4E-22 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_24195 37ccbe3ce9b5e3d9dad9469e878d18fd 156 Pfam PF12867 DinB superfamily 11 139 1.1E-11 T 14-10-2018 IPR024775 DinB-like domain C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 123 136 6.5E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 324 338 6.5E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 172 187 6.5E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 194 222 6.5E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 247 267 6.5E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 304 320 6.5E-41 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 PIRSF PIRSF001369 1 371 2.1E-150 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 SUPERFAMILY SSF48256 2 371 2.22E-134 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 Gene3D G3DSA:1.10.230.10 220 318 4.0E-124 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 7.4E-159 T 14-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 1.2E-126 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 C2I25_16330 56cc0531edd086ea7ae2c00c090635b6 371 Gene3D G3DSA:1.10.580.10 23 343 4.0E-124 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 C2I25_04525 3176967b381132cc5f0559e9b77a65cf 300 Pfam PF01636 Phosphotransferase enzyme family 23 247 1.5E-25 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_04525 3176967b381132cc5f0559e9b77a65cf 300 Gene3D G3DSA:3.30.200.20 1 96 9.3E-23 T 14-10-2018 C2I25_04525 3176967b381132cc5f0559e9b77a65cf 300 Gene3D G3DSA:3.90.1200.10 97 299 1.2E-49 T 14-10-2018 C2I25_04525 3176967b381132cc5f0559e9b77a65cf 300 SUPERFAMILY SSF56112 7 260 3.86E-31 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 2 463 43.557 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 SUPERFAMILY SSF52540 6 460 1.71E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 137 3.0E-6 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 SMART SM00382 50 352 9.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 355 425 5.4E-7 T 14-10-2018 IPR019489 Clp ATPase, C-terminal C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 Gene3D G3DSA:1.10.8.60 355 460 1.2E-39 T 14-10-2018 C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 Pfam PF07724 AAA domain (Cdc48 subfamily) 192 349 4.6E-41 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 463 9.1E-210 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 C2I25_20365 24d80dd8a85e8817b79fb7fc5f9c6535 463 SMART SM01086 355 449 3.2E-23 T 14-10-2018 IPR019489 Clp ATPase, C-terminal C2I25_01355 392e4bd2f9abbf11579e82f0ed1ba9da 215 PIRSF PIRSF035040 1 208 7.2E-88 T 14-10-2018 IPR017036 Uncharacterised conserved protein UCP035040, CBS-type C2I25_01355 392e4bd2f9abbf11579e82f0ed1ba9da 215 SUPERFAMILY SSF54631 1 121 1.12E-20 T 14-10-2018 C2I25_01355 392e4bd2f9abbf11579e82f0ed1ba9da 215 Pfam PF00571 CBS domain 9 59 2.8E-6 T 14-10-2018 IPR000644 CBS domain C2I25_01355 392e4bd2f9abbf11579e82f0ed1ba9da 215 Gene3D G3DSA:3.10.580.10 1 124 1.2E-20 T 14-10-2018 C2I25_24055 9d8536f1d685622ef1e1e8c399746e41 214 Gene3D G3DSA:3.40.50.850 1 209 2.4E-51 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_24055 9d8536f1d685622ef1e1e8c399746e41 214 Pfam PF00857 Isochorismatase family 14 165 2.8E-21 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_24055 9d8536f1d685622ef1e1e8c399746e41 214 SUPERFAMILY SSF52499 4 204 8.77E-53 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_09395 a781ddabdc608574fc1af47ce433fa72 332 Pfam PF09084 NMT1/THI5 like 44 258 8.9E-78 T 14-10-2018 IPR015168 SsuA/THI5-like C2I25_09395 a781ddabdc608574fc1af47ce433fa72 332 SUPERFAMILY SSF53850 37 320 1.59E-44 T 14-10-2018 C2I25_09395 a781ddabdc608574fc1af47ce433fa72 332 Gene3D G3DSA:3.40.190.10 39 327 1.4E-100 T 14-10-2018 C2I25_09395 a781ddabdc608574fc1af47ce433fa72 332 Gene3D G3DSA:3.40.190.10 116 218 1.4E-100 T 14-10-2018 C2I25_13125 2ffed0ff9cb345f871685d8d88a54b9c 364 SUPERFAMILY SSF48208 11 351 1.18E-47 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 C2I25_13125 2ffed0ff9cb345f871685d8d88a54b9c 364 Gene3D G3DSA:1.50.10.10 26 361 7.6E-97 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 C2I25_09140 dd55f590da302589997fe14bccb25204 473 Pfam PF00324 Amino acid permease 16 450 1.2E-127 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I25_09140 dd55f590da302589997fe14bccb25204 473 PIRSF PIRSF006060 1 469 8.5E-85 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_09140 dd55f590da302589997fe14bccb25204 473 ProSitePatterns PS00218 Amino acid permeases signature. 41 72 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I25_09140 dd55f590da302589997fe14bccb25204 473 Gene3D G3DSA:1.20.1740.10 7 471 2.2E-68 T 14-10-2018 C2I25_23260 14d248baf5d4775a974bd2e868779f65 159 Pfam PF03737 Aldolase/RraA 4 152 1.0E-41 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein C2I25_23260 14d248baf5d4775a974bd2e868779f65 159 SUPERFAMILY SSF89562 3 157 2.22E-43 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily C2I25_23260 14d248baf5d4775a974bd2e868779f65 159 TIGRFAM TIGR01935 NOT-MenG: RraA family 4 153 6.4E-54 T 14-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 C2I25_23260 14d248baf5d4775a974bd2e868779f65 159 Gene3D G3DSA:3.50.30.40 1 159 5.0E-59 T 14-10-2018 C2I25_16840 6394e8cb9a811be91584d0d85b7e5082 227 Gene3D G3DSA:3.40.50.880 2 226 1.1E-68 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_16840 6394e8cb9a811be91584d0d85b7e5082 227 Pfam PF01965 DJ-1/PfpI family 28 182 4.6E-10 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I25_16840 6394e8cb9a811be91584d0d85b7e5082 227 SUPERFAMILY SSF52317 1 225 6.3E-71 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_17760 a754cf391dbee4724081db8ff6d68f68 319 SUPERFAMILY SSF52540 98 279 6.4E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17760 a754cf391dbee4724081db8ff6d68f68 319 Gene3D G3DSA:3.40.50.300 109 316 1.6E-75 T 14-10-2018 C2I25_17760 a754cf391dbee4724081db8ff6d68f68 319 Pfam PF02562 PhoH-like protein 113 316 3.0E-95 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 C2I25_27550 63be6ea83e866546281486c4d375045e 558 SUPERFAMILY SSF52518 5 182 4.71E-47 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_27550 63be6ea83e866546281486c4d375045e 558 Gene3D G3DSA:3.40.50.970 356 549 2.2E-58 T 14-10-2018 C2I25_27550 63be6ea83e866546281486c4d375045e 558 PIRSF PIRSF036565 1 558 4.2E-221 T 14-10-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 C2I25_27550 63be6ea83e866546281486c4d375045e 558 SUPERFAMILY SSF52467 166 339 6.78E-37 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_27550 63be6ea83e866546281486c4d375045e 558 SUPERFAMILY SSF52518 365 553 8.94E-42 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_27550 63be6ea83e866546281486c4d375045e 558 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 179 6.8E-37 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I25_27550 63be6ea83e866546281486c4d375045e 558 Gene3D G3DSA:3.40.50.970 1 186 6.5E-81 T 14-10-2018 C2I25_27550 63be6ea83e866546281486c4d375045e 558 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 314 9.2E-29 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I25_27550 63be6ea83e866546281486c4d375045e 558 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 403 535 6.7E-18 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I25_27550 63be6ea83e866546281486c4d375045e 558 Gene3D G3DSA:3.40.50.1220 189 347 1.7E-52 T 14-10-2018 C2I25_13800 a8dbc2ee5cebf2ce40967222ec64761a 107 PIRSF PIRSF036521 1 107 5.9E-54 T 14-10-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related C2I25_13800 a8dbc2ee5cebf2ce40967222ec64761a 107 Gene3D G3DSA:1.10.287.1080 2 102 9.8E-24 T 14-10-2018 C2I25_13800 a8dbc2ee5cebf2ce40967222ec64761a 107 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 29 102 2.6E-11 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core C2I25_13800 a8dbc2ee5cebf2ce40967222ec64761a 107 SUPERFAMILY SSF101386 1 104 1.8E-24 T 14-10-2018 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 Gene3D G3DSA:3.20.20.70 93 356 3.2E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 Pfam PF00793 DAHP synthetase I family 110 351 1.2E-81 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 Gene3D G3DSA:1.20.59.10 8 92 3.7E-29 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 1.2E-122 T 14-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 SMART SM00830 10 89 3.3E-24 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 101 2.2E-43 T 14-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 SUPERFAMILY SSF48600 5 88 1.68E-21 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 SUPERFAMILY SSF51569 58 352 7.05E-102 T 14-10-2018 C2I25_24795 250acfbef897c7165ccbe6d3427224ef 358 Pfam PF01817 Chorismate mutase type II 10 87 1.3E-18 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 Pfam PF07690 Major Facilitator Superfamily 9 402 4.9E-59 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 8 32 3.2E-6 T 14-10-2018 C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 153 3.2E-6 T 14-10-2018 C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 67 89 3.2E-6 T 14-10-2018 C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 392 411 3.2E-6 T 14-10-2018 C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 SUPERFAMILY SSF103473 2 472 6.41E-72 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 414 6.6E-69 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 Gene3D G3DSA:1.20.1250.20 258 479 4.3E-20 T 14-10-2018 C2I25_15710 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 Gene3D G3DSA:1.20.1720.10 5 215 1.7E-57 T 14-10-2018 C2I25_25160 07e7635506f798f3aea530217c499df3 404 Gene3D G3DSA:1.20.1250.20 237 403 7.2E-16 T 14-10-2018 C2I25_25160 07e7635506f798f3aea530217c499df3 404 Gene3D G3DSA:1.20.1250.20 14 196 5.7E-26 T 14-10-2018 C2I25_25160 07e7635506f798f3aea530217c499df3 404 SUPERFAMILY SSF103473 9 394 2.49E-53 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_25160 07e7635506f798f3aea530217c499df3 404 Pfam PF07690 Major Facilitator Superfamily 250 390 3.3E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_25160 07e7635506f798f3aea530217c499df3 404 Pfam PF07690 Major Facilitator Superfamily 17 234 9.0E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 472 8.3E-182 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 SMART SM00845 325 472 6.0E-77 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 SUPERFAMILY SSF55931 4 293 1.11E-121 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 473 39.034 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 Gene3D G3DSA:1.10.150.380 297 410 3.1E-37 T 14-10-2018 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 Pfam PF02637 GatB domain 325 472 6.6E-56 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 SUPERFAMILY SSF89095 294 400 8.2E-36 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 Gene3D G3DSA:1.10.10.410 412 475 6.1E-26 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal C2I25_09760 bb977c461ee29e9251269488469a15c9 475 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 141 155 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 C2I25_09760 bb977c461ee29e9251269488469a15c9 475 Pfam PF02934 GatB/GatE catalytic domain 6 285 3.5E-112 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 C2I25_16400 252d43aca23c47c20b2300a2898b168d 130 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 32.254 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I25_16400 252d43aca23c47c20b2300a2898b168d 130 Gene3D G3DSA:3.30.360.110 4 65 8.4E-26 T 14-10-2018 C2I25_16400 252d43aca23c47c20b2300a2898b168d 130 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 3.0E-42 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I25_16400 252d43aca23c47c20b2300a2898b168d 130 SUPERFAMILY SSF56276 6 117 8.83E-42 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 C2I25_16400 252d43aca23c47c20b2300a2898b168d 130 Gene3D G3DSA:3.30.160.750 66 129 1.0E-19 T 14-10-2018 C2I25_16400 252d43aca23c47c20b2300a2898b168d 130 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 7.7E-37 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I25_09560 4c6b98fa2d3b48f1959721be8cec516e 421 Gene3D G3DSA:3.40.50.720 6 178 1.8E-12 T 14-10-2018 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 SUPERFAMILY SSF54814 181 297 2.12E-43 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 169 1.1E-31 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 1.4E-109 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 Gene3D G3DSA:3.40.50.300 4 185 1.2E-51 T 14-10-2018 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 Gene3D G3DSA:3.30.300.20 186 300 1.0E-43 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 SUPERFAMILY SSF52540 11 206 1.96E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 Pfam PF07650 KH domain 208 285 1.5E-21 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 3.0E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 3.0E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 8.0E-26 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17785 218f4936ab5f4d07a108a61a8f1d0e93 301 Hamap MF_00367 GTPase Era [era]. 6 296 39.463 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PRINTS PR00083 Histidinol dehydrogenase signature 168 194 1.5E-90 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PRINTS PR00083 Histidinol dehydrogenase signature 198 223 1.5E-90 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PRINTS PR00083 Histidinol dehydrogenase signature 249 268 1.5E-90 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 1.5E-90 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PRINTS PR00083 Histidinol dehydrogenase signature 359 377 1.5E-90 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PRINTS PR00083 Histidinol dehydrogenase signature 227 248 1.5E-90 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 1.5E-90 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PRINTS PR00083 Histidinol dehydrogenase signature 318 343 1.5E-90 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 227 259 - T 14-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 425 43.676 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 Pfam PF00815 Histidinol dehydrogenase 26 425 1.6E-177 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 SUPERFAMILY SSF53720 27 425 1.96E-84 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 PIRSF PIRSF000099 2 428 2.7E-184 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 424 4.9E-171 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 Gene3D G3DSA:3.40.50.1980 231 347 2.9E-129 T 14-10-2018 C2I25_04375 53e5ebb1e40bfe737ee1753c9b9cf3f9 429 Gene3D G3DSA:3.40.50.1980 30 229 2.9E-129 T 14-10-2018 C2I25_18600 de5f718f4cbb07d508cb4319bd8ee0f2 333 Gene3D G3DSA:3.40.50.970 2 333 3.4E-119 T 14-10-2018 C2I25_18600 de5f718f4cbb07d508cb4319bd8ee0f2 333 SUPERFAMILY SSF52518 10 333 6.14E-104 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_18600 de5f718f4cbb07d508cb4319bd8ee0f2 333 Pfam PF00676 Dehydrogenase E1 component 24 323 7.8E-105 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 C2I25_07135 632b89e7ed235b76953264f068656762 182 Pfam PF02525 Flavodoxin-like fold 2 168 1.1E-36 T 14-10-2018 IPR003680 Flavodoxin-like fold C2I25_07135 632b89e7ed235b76953264f068656762 182 Gene3D G3DSA:3.40.50.360 1 181 1.9E-54 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_07135 632b89e7ed235b76953264f068656762 182 SUPERFAMILY SSF52218 1 180 4.79E-42 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_18945 8f5fe1b415eb4a03a345911a3b64c014 158 Pfam PF12651 Ribbon-helix-helix domain 106 149 1.6E-11 T 14-10-2018 IPR038733 Predicted DNA-binding protein, ribbon-helix-helix domain C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 Gene3D G3DSA:3.40.1010.10 3 117 2.5E-8 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 SUPERFAMILY SSF53790 3 263 3.34E-33 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 SUPERFAMILY SSF101386 232 332 4.25E-25 T 14-10-2018 C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 Gene3D G3DSA:1.10.287.1080 356 485 6.7E-44 T 14-10-2018 C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 PIRSF PIRSF002845 1 486 1.5E-237 T 14-10-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 Gene3D G3DSA:1.10.287.1080 229 352 8.2E-45 T 14-10-2018 C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 TIGRFAM TIGR00444 mazG: MazG family protein 239 482 3.3E-101 T 14-10-2018 IPR011551 NTP pyrophosphohydrolase MazG C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 392 451 1.6E-7 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 255 328 1.5E-28 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 204 4.9E-24 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I25_11330 e3e557dcb023c6d3083aa62692c6f8b1 486 SUPERFAMILY SSF101386 362 460 4.22E-23 T 14-10-2018 C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 Pfam PF00288 GHMP kinases N terminal domain 90 147 2.3E-13 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 Gene3D G3DSA:3.30.230.10 1 162 2.2E-62 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 288 7.3E-111 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 PIRSF PIRSF010376 5 290 1.4E-99 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 282 36.28 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 Pfam PF08544 GHMP kinases C terminal 204 272 1.9E-7 T 14-10-2018 IPR013750 GHMP kinase, C-terminal domain C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 SUPERFAMILY SSF55060 164 284 2.16E-32 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 SUPERFAMILY SSF54211 6 160 1.52E-48 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_11385 2c1929e19f8088c666386db3cb7829b3 292 Gene3D G3DSA:3.30.70.890 165 287 2.4E-28 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I25_10625 c15311da7530ab85a47d6a5199a51d39 270 Pfam PF03180 NLPA lipoprotein 35 270 2.5E-87 T 14-10-2018 IPR004872 Lipoprotein NlpA family C2I25_10625 c15311da7530ab85a47d6a5199a51d39 270 Gene3D G3DSA:3.40.190.10 35 266 5.6E-88 T 14-10-2018 C2I25_10625 c15311da7530ab85a47d6a5199a51d39 270 Gene3D G3DSA:3.40.190.10 116 220 5.6E-88 T 14-10-2018 C2I25_10625 c15311da7530ab85a47d6a5199a51d39 270 SUPERFAMILY SSF53850 34 270 2.9E-78 T 14-10-2018 C2I25_10625 c15311da7530ab85a47d6a5199a51d39 270 PIRSF PIRSF002854 1 270 6.1E-92 T 14-10-2018 IPR004872 Lipoprotein NlpA family C2I25_22340 c49ca88a344af364086ce42b860260e0 151 SUPERFAMILY SSF109854 7 148 1.79E-24 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_22340 c49ca88a344af364086ce42b860260e0 151 Gene3D G3DSA:1.20.120.450 4 150 4.4E-15 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_22340 c49ca88a344af364086ce42b860260e0 151 Pfam PF12867 DinB superfamily 9 141 2.4E-20 T 14-10-2018 IPR024775 DinB-like domain C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 Pfam PF08239 Bacterial SH3 domain 234 277 4.7E-7 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 SMART SM00641 9 113 6.4E-19 T 14-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 Gene3D G3DSA:2.30.30.40 217 281 4.3E-9 T 14-10-2018 C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 Gene3D G3DSA:2.30.30.40 282 344 2.8E-7 T 14-10-2018 C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 SUPERFAMILY SSF51445 7 197 8.43E-57 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 Pfam PF01183 Glycosyl hydrolases family 25 12 190 3.6E-57 T 14-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 SMART SM00287 286 343 0.27 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 SMART SM00287 225 279 0.0029 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_21095 70f8bf004a6f94b2e111a6c6ebdce9c7 348 Gene3D G3DSA:3.20.20.80 1 208 8.4E-65 T 14-10-2018 C2I25_28470 3d67d93a3e0efe43eea0981ff01629ea 232 SMART SM00882 11 222 5.0E-67 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I25_28470 3d67d93a3e0efe43eea0981ff01629ea 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 12 222 1.4E-60 T 14-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 C2I25_28470 3d67d93a3e0efe43eea0981ff01629ea 232 Pfam PF01144 Coenzyme A transferase 13 220 3.1E-64 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I25_28470 3d67d93a3e0efe43eea0981ff01629ea 232 SUPERFAMILY SSF100950 10 224 1.56E-73 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_28470 3d67d93a3e0efe43eea0981ff01629ea 232 Gene3D G3DSA:3.40.1080.10 9 224 9.0E-76 T 14-10-2018 C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 SUPERFAMILY SSF46785 1 86 7.27E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 SUPERFAMILY SSF53850 89 291 5.32E-35 T 14-10-2018 C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 Gene3D G3DSA:1.10.10.10 1 85 5.1E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.3E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 Gene3D G3DSA:3.40.190.10 162 267 2.3E-65 T 14-10-2018 C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 Gene3D G3DSA:3.40.190.10 88 285 2.3E-65 T 14-10-2018 C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_21140 b7d48abd59bcbfffdf4f65a6797badda 300 Pfam PF03466 LysR substrate binding domain 87 291 8.4E-41 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_06320 21b3e054d94d583c0871014339dc8375 325 SUPERFAMILY SSF54593 3 303 3.12E-46 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_06320 21b3e054d94d583c0871014339dc8375 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 167 264 2.0E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_06320 21b3e054d94d583c0871014339dc8375 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 124 2.6E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_06320 21b3e054d94d583c0871014339dc8375 325 Gene3D G3DSA:3.10.180.10 5 309 1.1E-109 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_06320 21b3e054d94d583c0871014339dc8375 325 Gene3D G3DSA:3.10.180.10 66 217 1.1E-109 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_01470 93c8993cb8658e8453095558037d2714 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 470 3.3E-77 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_01470 93c8993cb8658e8453095558037d2714 553 Gene3D G3DSA:3.40.190.10 56 540 2.1E-177 T 14-10-2018 C2I25_01470 93c8993cb8658e8453095558037d2714 553 Gene3D G3DSA:3.10.105.10 298 523 2.1E-177 T 14-10-2018 C2I25_01470 93c8993cb8658e8453095558037d2714 553 PIRSF PIRSF002741 1 553 8.7E-101 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_01470 93c8993cb8658e8453095558037d2714 553 SUPERFAMILY SSF53850 38 549 5.43E-118 T 14-10-2018 C2I25_01470 93c8993cb8658e8453095558037d2714 553 Gene3D G3DSA:3.90.76.10 75 196 2.1E-177 T 14-10-2018 C2I25_22835 ba83a3a82c892b2266cef45eb2d9d3ea 357 SUPERFAMILY SSF110296 19 343 6.15E-46 T 14-10-2018 C2I25_22835 ba83a3a82c892b2266cef45eb2d9d3ea 357 Gene3D G3DSA:2.130.10.10 6 341 5.7E-61 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_06725 b5b91af374b04a36b562d5182f71c25b 287 Gene3D G3DSA:1.10.10.630 167 239 2.2E-19 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_06725 b5b91af374b04a36b562d5182f71c25b 287 Pfam PF07261 Replication initiation and membrane attachment 171 239 1.4E-16 T 14-10-2018 IPR006343 DnaD domain C2I25_06725 b5b91af374b04a36b562d5182f71c25b 287 SUPERFAMILY SSF158499 170 231 7.19E-17 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_06725 b5b91af374b04a36b562d5182f71c25b 287 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 171 238 1.3E-18 T 14-10-2018 IPR006343 DnaD domain C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 Gene3D G3DSA:1.20.210.10 2 527 4.1E-207 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 375 394 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 242 263 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 191 210 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 312 333 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 303 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 114 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 144 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 16 41 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 86 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 180 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 425 446 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 365 7.3E-106 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 468 5.9E-148 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 244 298 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 17 519 7.8E-207 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 C2I25_19780 cf6792c3f87901fdbc1991ee33535219 620 SUPERFAMILY SSF81442 14 521 1.7E-181 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_08245 91344cb329f5b758e0f7dc2bec343cfe 225 SMART SM00862 143 220 3.4E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_08245 91344cb329f5b758e0f7dc2bec343cfe 225 SMART SM00448 2 112 2.2E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_08245 91344cb329f5b758e0f7dc2bec343cfe 225 Pfam PF00072 Response regulator receiver domain 4 113 4.5E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_08245 91344cb329f5b758e0f7dc2bec343cfe 225 Gene3D G3DSA:1.10.10.10 126 224 3.2E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_08245 91344cb329f5b758e0f7dc2bec343cfe 225 Gene3D G3DSA:3.40.50.2300 1 125 2.9E-41 T 14-10-2018 C2I25_08245 91344cb329f5b758e0f7dc2bec343cfe 225 SUPERFAMILY SSF52172 1 172 5.41E-44 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_08245 91344cb329f5b758e0f7dc2bec343cfe 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 6.1E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_12190 7cecf55c34d0c49d1cef937a8f7987ec 273 Gene3D G3DSA:3.30.1240.10 87 191 1.3E-88 T 14-10-2018 C2I25_12190 7cecf55c34d0c49d1cef937a8f7987ec 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 216 238 - T 14-10-2018 C2I25_12190 7cecf55c34d0c49d1cef937a8f7987ec 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 261 2.8E-70 T 14-10-2018 C2I25_12190 7cecf55c34d0c49d1cef937a8f7987ec 273 Gene3D G3DSA:3.40.50.1000 4 263 1.3E-88 T 14-10-2018 IPR023214 HAD superfamily C2I25_12190 7cecf55c34d0c49d1cef937a8f7987ec 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 3.7E-27 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_12190 7cecf55c34d0c49d1cef937a8f7987ec 273 SUPERFAMILY SSF56784 1 267 1.4E-76 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_12190 7cecf55c34d0c49d1cef937a8f7987ec 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 261 1.3E-69 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_15310 128d43b0563d5302d680372bc1873480 325 SUPERFAMILY SSF53850 22 249 3.51E-34 T 14-10-2018 C2I25_15310 128d43b0563d5302d680372bc1873480 325 Gene3D G3DSA:3.40.190.10 135 324 9.0E-31 T 14-10-2018 C2I25_15310 128d43b0563d5302d680372bc1873480 325 Pfam PF13379 NMT1-like family 24 255 1.6E-27 T 14-10-2018 C2I25_15310 128d43b0563d5302d680372bc1873480 325 Gene3D G3DSA:3.40.190.10 18 119 3.9E-17 T 14-10-2018 C2I25_03595 56397bbd4d54c82f3a6f66ca35126062 111 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 4.0E-16 T 14-10-2018 IPR019933 DivIVA domain C2I25_03595 56397bbd4d54c82f3a6f66ca35126062 111 PIRSF PIRSF029938 1 111 2.1E-48 T 14-10-2018 IPR011229 Cell cycle protein GpsB C2I25_03595 56397bbd4d54c82f3a6f66ca35126062 111 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 107 23.874 T 14-10-2018 IPR011229 Cell cycle protein GpsB C2I25_03595 56397bbd4d54c82f3a6f66ca35126062 111 Pfam PF05103 DivIVA protein 8 66 3.2E-19 T 14-10-2018 IPR007793 DivIVA family C2I25_12555 782de983eac5cd0715d14225810a9813 92 Pfam PF13071 Protein of unknown function (DUF3935) 2 71 6.1E-48 T 14-10-2018 IPR025176 Protein of unknown function DUF3935 C2I25_18820 2c6ff6da182c9d6c153f51f1bd76cf25 148 SMART SM00347 29 129 3.2E-19 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_18820 2c6ff6da182c9d6c153f51f1bd76cf25 148 Pfam PF01047 MarR family 39 93 3.7E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_18820 2c6ff6da182c9d6c153f51f1bd76cf25 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 9.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_18820 2c6ff6da182c9d6c153f51f1bd76cf25 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 9.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_18820 2c6ff6da182c9d6c153f51f1bd76cf25 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 9.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_18820 2c6ff6da182c9d6c153f51f1bd76cf25 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 9.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_18820 2c6ff6da182c9d6c153f51f1bd76cf25 148 SUPERFAMILY SSF46785 28 143 5.17E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_18820 2c6ff6da182c9d6c153f51f1bd76cf25 148 Gene3D G3DSA:1.10.10.10 1 143 2.9E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_28110 e3d6c838b80c0d9d203ff656ad3c4fc7 397 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 331 341 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I25_28110 e3d6c838b80c0d9d203ff656ad3c4fc7 397 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 142 153 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I25_28110 e3d6c838b80c0d9d203ff656ad3c4fc7 397 Pfam PF00082 Subtilase family 139 369 1.9E-50 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I25_28110 e3d6c838b80c0d9d203ff656ad3c4fc7 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 137 156 8.7E-22 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_28110 e3d6c838b80c0d9d203ff656ad3c4fc7 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 330 346 8.7E-22 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_28110 e3d6c838b80c0d9d203ff656ad3c4fc7 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 175 188 8.7E-22 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_28110 e3d6c838b80c0d9d203ff656ad3c4fc7 397 SUPERFAMILY SSF52743 119 390 5.89E-92 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_28110 e3d6c838b80c0d9d203ff656ad3c4fc7 397 Gene3D G3DSA:3.40.50.200 109 387 3.7E-101 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_09765 35fb31b804804e9ae5f164082cf9498b 485 Pfam PF01425 Amidase 24 465 2.3E-162 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_09765 35fb31b804804e9ae5f164082cf9498b 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 98.156 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_09765 35fb31b804804e9ae5f164082cf9498b 485 SUPERFAMILY SSF75304 1 480 2.22E-167 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_09765 35fb31b804804e9ae5f164082cf9498b 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 1.1E-203 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_09765 35fb31b804804e9ae5f164082cf9498b 485 ProSitePatterns PS00571 Amidases signature. 151 182 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 C2I25_09765 35fb31b804804e9ae5f164082cf9498b 485 Gene3D G3DSA:3.90.1300.10 2 485 4.5E-200 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 Pfam PF13354 Beta-lactamase enzyme family 78 287 4.3E-36 T 14-10-2018 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 Gene3D G3DSA:3.40.710.10 42 312 1.2E-77 T 14-10-2018 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 ProSitePatterns PS00146 Beta-lactamase class-A active site. 91 106 - T 14-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 PRINTS PR00118 Beta-lactamase class A signature 247 262 4.2E-54 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 PRINTS PR00118 Beta-lactamase class A signature 191 216 4.2E-54 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 PRINTS PR00118 Beta-lactamase class A signature 89 106 4.2E-54 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 PRINTS PR00118 Beta-lactamase class A signature 58 82 4.2E-54 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 PRINTS PR00118 Beta-lactamase class A signature 129 154 4.2E-54 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 PRINTS PR00118 Beta-lactamase class A signature 165 189 4.2E-54 T 14-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I25_23650 9ec0b6852de97a0d08560536c56ecb0d 319 SUPERFAMILY SSF56601 57 315 1.4E-75 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_10775 18e6486417f6fbf64382b613efbec4e2 203 SMART SM01251 17 196 2.2E-119 T 14-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 C2I25_10775 18e6486417f6fbf64382b613efbec4e2 203 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 195 6.3E-79 T 14-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 C2I25_10775 18e6486417f6fbf64382b613efbec4e2 203 PIRSF PIRSF029886 1 199 1.7E-78 T 14-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 C2I25_17615 9cf50914db181c75b0ca69a2f435cd1a 189 SUPERFAMILY SSF52374 3 187 4.69E-50 T 14-10-2018 C2I25_17615 9cf50914db181c75b0ca69a2f435cd1a 189 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 8.3E-56 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 C2I25_17615 9cf50914db181c75b0ca69a2f435cd1a 189 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 30.858 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 C2I25_17615 9cf50914db181c75b0ca69a2f435cd1a 189 Gene3D G3DSA:3.40.50.620 1 188 6.3E-64 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_17615 9cf50914db181c75b0ca69a2f435cd1a 189 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 67 9.0E-11 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I25_17615 9cf50914db181c75b0ca69a2f435cd1a 189 Pfam PF01467 Cytidylyltransferase-like 6 162 1.4E-31 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 219 5.3E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 SUPERFAMILY SSF47384 141 221 2.35E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 SMART SM00388 156 223 7.7E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 7.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 7.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 357 7.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 Gene3D G3DSA:3.30.565.10 227 383 6.2E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 SMART SM00387 268 378 1.6E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 SUPERFAMILY SSF55874 213 378 7.73E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 Gene3D G3DSA:1.10.287.130 120 221 6.8E-15 T 14-10-2018 C2I25_22110 5dbc47b44251a9aa38dc30cba4559411 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 376 2.6E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08385 150157954d749189cdd52934d38f4799 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 240 2.1E-27 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_08385 150157954d749189cdd52934d38f4799 321 Gene3D G3DSA:3.40.50.720 1 317 2.1E-104 T 14-10-2018 C2I25_08385 150157954d749189cdd52934d38f4799 321 SUPERFAMILY SSF51735 1 313 1.69E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_07555 a4d0690efecb337330515291caa2e8d6 458 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 3 452 7.7E-192 T 14-10-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 C2I25_07555 a4d0690efecb337330515291caa2e8d6 458 Pfam PF00367 phosphotransferase system, EIIB 9 41 2.1E-14 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_07555 a4d0690efecb337330515291caa2e8d6 458 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 153 441 9.4E-90 T 14-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 C2I25_07555 a4d0690efecb337330515291caa2e8d6 458 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_07555 a4d0690efecb337330515291caa2e8d6 458 Pfam PF02378 Phosphotransferase system, EIIC 110 396 2.2E-53 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_07555 a4d0690efecb337330515291caa2e8d6 458 Gene3D G3DSA:3.30.1360.60 1 78 8.9E-27 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_07555 a4d0690efecb337330515291caa2e8d6 458 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 111 1.9E-16 T 14-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I25_07555 a4d0690efecb337330515291caa2e8d6 458 SUPERFAMILY SSF55604 6 82 3.53E-21 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_03275 c24dbd2af84c95fc0f9b12abe274d8f2 241 Pfam PF01925 Sulfite exporter TauE/SafE 8 233 2.6E-31 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I25_07525 707331b5b4bac5b2f8d0c004faf12b53 170 Pfam PF13798 Protein of unknown function with PCYCGC motif 9 168 1.3E-72 T 14-10-2018 IPR025673 Protein of unknown function with PCYCGC motif C2I25_24775 6d6deec40ebc902cec372cba2695ee73 176 SUPERFAMILY SSF52499 2 158 4.84E-48 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_24775 6d6deec40ebc902cec372cba2695ee73 176 Gene3D G3DSA:3.40.50.850 1 176 8.5E-50 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_24775 6d6deec40ebc902cec372cba2695ee73 176 Pfam PF00857 Isochorismatase family 4 144 1.1E-40 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_03575 c413d566f13742eb56ab779a9e99eb1e 645 SMART SM00491 503 627 1.9E-7 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 C2I25_03575 c413d566f13742eb56ab779a9e99eb1e 645 Pfam PF13307 Helicase C-terminal domain 488 621 1.2E-24 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 C2I25_03575 c413d566f13742eb56ab779a9e99eb1e 645 Gene3D G3DSA:3.40.50.300 38 320 2.3E-28 T 14-10-2018 C2I25_03575 c413d566f13742eb56ab779a9e99eb1e 645 Gene3D G3DSA:3.40.50.300 463 631 3.4E-27 T 14-10-2018 C2I25_03575 c413d566f13742eb56ab779a9e99eb1e 645 SUPERFAMILY SSF52540 53 623 1.01E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02210 48dd40db41ed279c065205876ea5ccd6 393 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 392 6.0E-139 T 14-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 C2I25_02210 48dd40db41ed279c065205876ea5ccd6 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 3.7E-62 T 14-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I25_02210 48dd40db41ed279c065205876ea5ccd6 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 1.2E-23 T 14-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I25_10285 ced903e83b04148ee509a1480f69793c 320 Gene3D G3DSA:3.20.20.150 2 309 3.8E-100 T 14-10-2018 C2I25_10285 ced903e83b04148ee509a1480f69793c 320 SUPERFAMILY SSF51658 49 294 6.53E-14 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily C2I25_10285 ced903e83b04148ee509a1480f69793c 320 Pfam PF03851 UV-endonuclease UvdE 5 274 8.8E-92 T 14-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 C2I25_10285 ced903e83b04148ee509a1480f69793c 320 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 2 303 2.6E-70 T 14-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 C2I25_26820 5d216ea5b127dae4d5e3ee183a17365d 194 SUPERFAMILY SSF55729 11 184 2.66E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26820 5d216ea5b127dae4d5e3ee183a17365d 194 Gene3D G3DSA:3.40.630.30 9 194 5.3E-34 T 14-10-2018 C2I25_26820 5d216ea5b127dae4d5e3ee183a17365d 194 Pfam PF13302 Acetyltransferase (GNAT) domain 17 168 1.3E-21 T 14-10-2018 IPR000182 GNAT domain C2I25_00155 6cad3407cc66e6959d518799a6ddb2d6 297 SUPERFAMILY SSF82861 22 104 1.83E-11 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 C2I25_00155 6cad3407cc66e6959d518799a6ddb2d6 297 SUPERFAMILY SSF50182 106 169 7.85E-10 T 14-10-2018 IPR010920 LSM domain superfamily C2I25_00155 6cad3407cc66e6959d518799a6ddb2d6 297 SUPERFAMILY SSF82689 171 281 2.48E-9 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 C2I25_00155 6cad3407cc66e6959d518799a6ddb2d6 297 Pfam PF00924 Mechanosensitive ion channel 65 272 2.3E-33 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 C2I25_00155 6cad3407cc66e6959d518799a6ddb2d6 297 Gene3D G3DSA:2.30.30.60 121 171 1.5E-17 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily C2I25_00155 6cad3407cc66e6959d518799a6ddb2d6 297 Gene3D G3DSA:3.30.70.100 173 271 7.2E-9 T 14-10-2018 C2I25_13925 56bd8bedee6a6b66684afda6357baa64 204 Pfam PF09335 SNARE associated Golgi protein 29 154 6.4E-18 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_08725 0f6c41996ecc1b12f7429867c44ed948 287 Gene3D G3DSA:3.40.630.30 2 145 7.6E-6 T 14-10-2018 C2I25_08725 0f6c41996ecc1b12f7429867c44ed948 287 SUPERFAMILY SSF55729 153 283 6.35E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_08725 0f6c41996ecc1b12f7429867c44ed948 287 Gene3D G3DSA:3.40.630.30 152 287 3.3E-22 T 14-10-2018 C2I25_08725 0f6c41996ecc1b12f7429867c44ed948 287 Pfam PF00583 Acetyltransferase (GNAT) family 183 275 1.5E-13 T 14-10-2018 IPR000182 GNAT domain C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 Gene3D G3DSA:2.40.50.140 96 180 3.9E-12 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 Gene3D G3DSA:2.40.50.140 184 263 3.2E-31 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 SUPERFAMILY SSF50249 259 347 1.79E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 Gene3D G3DSA:2.40.50.140 3 95 4.7E-18 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 SUPERFAMILY SSF50249 186 271 6.08E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 SUPERFAMILY SSF50249 5 107 3.43E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 SUPERFAMILY SSF50249 88 170 4.03E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 Pfam PF00575 S1 RNA binding domain 100 168 8.5E-15 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 Pfam PF00575 S1 RNA binding domain 15 82 3.7E-14 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 Pfam PF00575 S1 RNA binding domain 271 343 4.5E-24 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 Pfam PF00575 S1 RNA binding domain 186 257 9.2E-26 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 SMART SM00316 272 343 3.2E-26 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 SMART SM00316 101 168 1.0E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 SMART SM00316 16 85 5.5E-14 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 SMART SM00316 187 257 1.0E-28 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 82 101 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 18 36 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 209 230 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 36 50 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 152 172 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 326 344 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 106 122 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 123 140 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 PRINTS PR00681 Ribosomal protein S1 signature 287 306 4.7E-56 T 14-10-2018 C2I25_03910 df388df6c7ea3bce517d5cba050d27b1 382 Gene3D G3DSA:2.40.50.140 264 347 2.0E-26 T 14-10-2018 C2I25_03980 9ecfe56d420a80088265c50186420195 509 Gene3D G3DSA:3.40.50.300 1 197 6.8E-66 T 14-10-2018 C2I25_03980 9ecfe56d420a80088265c50186420195 509 SMART SM00490 241 323 1.8E-23 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_03980 9ecfe56d420a80088265c50186420195 509 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 348 1.1E-102 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 C2I25_03980 9ecfe56d420a80088265c50186420195 509 SUPERFAMILY SSF52540 55 344 9.69E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03980 9ecfe56d420a80088265c50186420195 509 SMART SM00487 12 207 5.2E-28 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_03980 9ecfe56d420a80088265c50186420195 509 Pfam PF00270 DEAD/DEAH box helicase 18 176 1.3E-21 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_03980 9ecfe56d420a80088265c50186420195 509 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 130 139 - T 14-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site C2I25_03980 9ecfe56d420a80088265c50186420195 509 Pfam PF00271 Helicase conserved C-terminal domain 227 322 1.5E-16 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 454 2.6E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 Gene3D G3DSA:1.20.1480.50 146 233 2.2E-17 T 14-10-2018 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 1.3E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 1.3E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 1.3E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 1.3E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 Pfam PF00672 HAMP domain 181 228 1.0E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 SMART SM00304 181 233 8.9E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 SMART SM00388 234 300 4.4E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 SMART SM00387 345 457 2.2E-41 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 Gene3D G3DSA:3.30.565.10 299 462 2.9E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 SUPERFAMILY SSF55874 290 455 1.83E-48 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 Gene3D G3DSA:1.10.287.130 234 298 1.3E-18 T 14-10-2018 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 SUPERFAMILY SSF158472 181 229 1.57E-10 T 14-10-2018 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 SUPERFAMILY SSF47384 218 301 2.55E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_08250 71352c1a69748d951c79f0ef1b5739e8 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 8.5E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_12820 ae3d04ef3447e54f5fbd5df895334537 602 Gene3D G3DSA:3.40.50.720 133 260 3.2E-38 T 14-10-2018 C2I25_12820 ae3d04ef3447e54f5fbd5df895334537 602 SUPERFAMILY SSF51735 276 540 4.0E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_12820 ae3d04ef3447e54f5fbd5df895334537 602 Pfam PF13727 CoA-binding domain 71 234 4.7E-19 T 14-10-2018 C2I25_12820 ae3d04ef3447e54f5fbd5df895334537 602 Gene3D G3DSA:3.90.25.30 442 541 7.1E-118 T 14-10-2018 C2I25_12820 ae3d04ef3447e54f5fbd5df895334537 602 Pfam PF02719 Polysaccharide biosynthesis protein 279 560 8.5E-124 T 14-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain C2I25_12820 ae3d04ef3447e54f5fbd5df895334537 602 SUPERFAMILY SSF53335 102 302 1.66E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_12820 ae3d04ef3447e54f5fbd5df895334537 602 Gene3D G3DSA:3.40.50.720 277 558 7.1E-118 T 14-10-2018 C2I25_06620 e4bbed2c6bc0e0a0d138dabab250379e 469 SUPERFAMILY SSF53474 106 448 2.15E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_06620 e4bbed2c6bc0e0a0d138dabab250379e 469 Gene3D G3DSA:3.40.50.1820 104 468 1.9E-73 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_06620 e4bbed2c6bc0e0a0d138dabab250379e 469 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 283 416 2.5E-10 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 C2I25_06620 e4bbed2c6bc0e0a0d138dabab250379e 469 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 107 247 1.0E-8 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 C2I25_23475 286cc8ffa961205b18466ff53385636a 125 Gene3D G3DSA:3.10.129.10 1 124 9.4E-19 T 14-10-2018 C2I25_23475 286cc8ffa961205b18466ff53385636a 125 SUPERFAMILY SSF54637 3 122 5.93E-17 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_21970 77ff3a2580fc7bc0805d3c27ec776592 412 Pfam PF07968 Leukocidin/Hemolysin toxin family 62 313 4.0E-79 T 14-10-2018 IPR016183 Leukocidin/Hemolysin toxin GO:0005576|GO:0051715 C2I25_21970 77ff3a2580fc7bc0805d3c27ec776592 412 TIGRFAM TIGR01002 hlyII: beta-channel forming cytolysin 3 318 2.1E-124 T 14-10-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 C2I25_21970 77ff3a2580fc7bc0805d3c27ec776592 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 66 85 1.5E-5 T 14-10-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 C2I25_21970 77ff3a2580fc7bc0805d3c27ec776592 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 126 147 1.5E-5 T 14-10-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 C2I25_21970 77ff3a2580fc7bc0805d3c27ec776592 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 249 266 1.5E-5 T 14-10-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 C2I25_21970 77ff3a2580fc7bc0805d3c27ec776592 412 Gene3D G3DSA:2.70.240.10 29 317 2.9E-96 T 14-10-2018 C2I25_21970 77ff3a2580fc7bc0805d3c27ec776592 412 SUPERFAMILY SSF56959 36 328 8.01E-91 T 14-10-2018 IPR036435 Leukocidin/porin MspA superfamily C2I25_09990 2e24930a474adfe908783f09e5bd98dd 258 SUPERFAMILY SSF53335 49 214 1.16E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_09990 2e24930a474adfe908783f09e5bd98dd 258 Pfam PF08242 Methyltransferase domain 80 174 1.5E-12 T 14-10-2018 IPR013217 Methyltransferase type 12 C2I25_09990 2e24930a474adfe908783f09e5bd98dd 258 Gene3D G3DSA:3.40.50.150 45 213 3.7E-19 T 14-10-2018 C2I25_19110 eba8ba9efefcc50d41b056b0694652ac 206 Pfam PF12164 Stage V sporulation protein AA 2 88 1.9E-20 T 14-10-2018 IPR021997 Stage V sporulation protein AA C2I25_19110 eba8ba9efefcc50d41b056b0694652ac 206 Gene3D G3DSA:2.60.480.10 1 97 3.2E-15 T 14-10-2018 IPR038548 Stage V sporulation protein AA, N-terminal domain superfamily C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 Gene3D G3DSA:1.10.1760.20 79 218 6.3E-6 T 14-10-2018 C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 SUPERFAMILY SSF55781 237 361 5.89E-9 T 14-10-2018 C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 SMART SM00387 468 577 1.4E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 474 575 6.1E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 SMART SM00065 235 370 1.8E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 SUPERFAMILY SSF55874 430 574 9.3E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 Pfam PF06580 Histidine kinase 375 453 1.2E-24 T 14-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 238 361 5.1E-7 T 14-10-2018 IPR039472 Sporulation stage V protein T, GAF domain C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 Gene3D G3DSA:3.30.450.40 238 361 5.6E-7 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 Pfam PF07694 5TMR of 5TMR-LYT 26 204 2.2E-49 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I25_11970 624242e6ff8f8634e0a58f1770c5f6a6 589 Gene3D G3DSA:3.30.565.10 425 578 3.6E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_14940 cf9e084ee838c5e9fd2ef3ec34585e8c 367 Gene3D G3DSA:3.40.640.10 24 277 3.7E-48 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_14940 cf9e084ee838c5e9fd2ef3ec34585e8c 367 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 6 364 5.4E-168 T 14-10-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 C2I25_14940 cf9e084ee838c5e9fd2ef3ec34585e8c 367 Pfam PF03841 L-seryl-tRNA selenium transferase 57 277 2.2E-12 T 14-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 C2I25_14940 cf9e084ee838c5e9fd2ef3ec34585e8c 367 SUPERFAMILY SSF53383 10 363 1.53E-37 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_10945 c4d4b3e291d33e5ac0c9919282ebc665 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.666 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10945 c4d4b3e291d33e5ac0c9919282ebc665 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.3E-53 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10945 c4d4b3e291d33e5ac0c9919282ebc665 113 SUPERFAMILY SSF54843 1 112 5.76E-45 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_10945 c4d4b3e291d33e5ac0c9919282ebc665 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 5.2E-38 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 C2I25_10945 c4d4b3e291d33e5ac0c9919282ebc665 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10945 c4d4b3e291d33e5ac0c9919282ebc665 113 Gene3D G3DSA:3.90.470.10 1 113 3.0E-51 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_22595 5b251abebe9916316417d88794a73600 91 Gene3D G3DSA:1.10.10.10 1 91 3.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22595 5b251abebe9916316417d88794a73600 91 SUPERFAMILY SSF46785 4 90 8.2E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22595 5b251abebe9916316417d88794a73600 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 9.0E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22595 5b251abebe9916316417d88794a73600 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 9.0E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22595 5b251abebe9916316417d88794a73600 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 9.0E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22595 5b251abebe9916316417d88794a73600 91 Pfam PF12840 Helix-turn-helix domain 12 71 1.4E-8 T 14-10-2018 C2I25_22595 5b251abebe9916316417d88794a73600 91 SMART SM00418 13 91 3.8E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_11795 ea6f8e35e19ae087ec73482907ff1293 280 Pfam PF09648 YycH protein 33 252 9.0E-60 T 14-10-2018 IPR018604 Regulatory protein YycH-like GO:0016021 C2I25_11795 ea6f8e35e19ae087ec73482907ff1293 280 Gene3D G3DSA:3.10.450.660 47 256 3.1E-61 T 14-10-2018 C2I25_11795 ea6f8e35e19ae087ec73482907ff1293 280 Gene3D G3DSA:3.30.310.160 70 179 3.1E-61 T 14-10-2018 C2I25_18340 2c27b849e08117fe372f7f903b76e424 192 Gene3D G3DSA:3.40.630.30 1 167 8.8E-26 T 14-10-2018 C2I25_18340 2c27b849e08117fe372f7f903b76e424 192 SUPERFAMILY SSF55729 3 138 7.19E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_18340 2c27b849e08117fe372f7f903b76e424 192 Pfam PF13302 Acetyltransferase (GNAT) domain 4 138 4.2E-17 T 14-10-2018 IPR000182 GNAT domain C2I25_10655 6239cc423471428c0c585e93bfc810f3 188 Pfam PF14066 Protein of unknown function (DUF4256) 16 188 5.1E-93 T 14-10-2018 IPR025352 Protein of unknown function DUF4256 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 Gene3D G3DSA:1.10.275.10 26 230 5.6E-199 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 Gene3D G3DSA:1.10.40.30 361 433 5.6E-199 T 14-10-2018 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 1.2E-29 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 1.2E-29 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 1.2E-29 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 1.2E-29 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 2.3E-70 T 14-10-2018 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 2.3E-70 T 14-10-2018 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 2.3E-70 T 14-10-2018 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 2.3E-70 T 14-10-2018 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 2.3E-70 T 14-10-2018 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 2.3E-70 T 14-10-2018 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 Gene3D G3DSA:1.20.200.10 120 448 5.6E-199 T 14-10-2018 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 Pfam PF00206 Lyase 7 301 1.4E-83 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 453 5.4E-214 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 5.7E-24 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 45.248 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_16150 3ef7b3c59389db2449a5a6227d6eb6e9 462 SUPERFAMILY SSF48557 7 456 5.81E-155 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I25_20715 3443d44fc7791e969479b8fcf37fb669 329 SUPERFAMILY SSF51695 33 324 7.32E-63 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_20715 3443d44fc7791e969479b8fcf37fb669 329 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 59 194 3.5E-15 T 14-10-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain C2I25_20715 3443d44fc7791e969479b8fcf37fb669 329 Gene3D G3DSA:3.20.20.190 32 329 1.2E-122 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_20715 3443d44fc7791e969479b8fcf37fb669 329 SMART SM00148 50 194 5.2E-58 T 14-10-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain C2I25_18865 9f659fe093df1614220eecc541d9fb14 246 Gene3D G3DSA:3.40.50.1820 4 232 2.0E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_18865 9f659fe093df1614220eecc541d9fb14 246 SUPERFAMILY SSF53474 6 232 1.77E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_18865 9f659fe093df1614220eecc541d9fb14 246 Pfam PF12146 Serine aminopeptidase, S33 42 215 9.9E-11 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 C2I25_05950 50a534096dbf46e8d5b9b4ebf899c57c 510 SUPERFAMILY SSF56801 2 509 3.53E-164 T 14-10-2018 C2I25_05950 50a534096dbf46e8d5b9b4ebf899c57c 510 Gene3D G3DSA:3.40.50.12780 1 407 2.6E-130 T 14-10-2018 C2I25_05950 50a534096dbf46e8d5b9b4ebf899c57c 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_05950 50a534096dbf46e8d5b9b4ebf899c57c 510 Pfam PF00501 AMP-binding enzyme 8 414 4.6E-117 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_05950 50a534096dbf46e8d5b9b4ebf899c57c 510 PRINTS PR00154 AMP-binding signature 164 175 6.5E-5 T 14-10-2018 IPR020459 AMP-binding C2I25_05950 50a534096dbf46e8d5b9b4ebf899c57c 510 PRINTS PR00154 AMP-binding signature 176 184 6.5E-5 T 14-10-2018 IPR020459 AMP-binding C2I25_05950 50a534096dbf46e8d5b9b4ebf899c57c 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 497 3.4E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_05950 50a534096dbf46e8d5b9b4ebf899c57c 510 Gene3D G3DSA:3.30.300.310 410 510 2.5E-34 T 14-10-2018 C2I25_17400 20a3856a80a5f8d9a345a4eabca28601 212 Hamap MF_02100 Uncharacterized methyltransferase . 2 212 45.639 T 14-10-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 C2I25_17400 20a3856a80a5f8d9a345a4eabca28601 212 Pfam PF08241 Methyltransferase domain 50 143 2.2E-14 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_17400 20a3856a80a5f8d9a345a4eabca28601 212 SUPERFAMILY SSF53335 8 199 7.63E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_17400 20a3856a80a5f8d9a345a4eabca28601 212 Gene3D G3DSA:3.40.50.150 24 212 3.8E-55 T 14-10-2018 C2I25_02805 cf3edc2ec7f4d60a39820a724d66d1a3 395 Gene3D G3DSA:3.40.50.300 1 228 1.2E-73 T 14-10-2018 C2I25_02805 cf3edc2ec7f4d60a39820a724d66d1a3 395 SMART SM00833 256 371 7.3E-52 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I25_02805 cf3edc2ec7f4d60a39820a724d66d1a3 395 Gene3D G3DSA:3.30.1220.10 238 371 1.0E-5 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily C2I25_02805 cf3edc2ec7f4d60a39820a724d66d1a3 395 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 209 2.6E-57 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain C2I25_02805 cf3edc2ec7f4d60a39820a724d66d1a3 395 SUPERFAMILY SSF52540 2 309 4.38E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02805 cf3edc2ec7f4d60a39820a724d66d1a3 395 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 256 371 1.8E-27 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I25_17415 0eb2aca2a959ffe0ecec34c92e154648 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_17415 0eb2aca2a959ffe0ecec34c92e154648 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 376 1.2E-158 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_17415 0eb2aca2a959ffe0ecec34c92e154648 377 Gene3D G3DSA:3.90.1150.10 246 377 2.2E-53 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_17415 0eb2aca2a959ffe0ecec34c92e154648 377 PIRSF PIRSF001434 1 377 2.3E-149 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_17415 0eb2aca2a959ffe0ecec34c92e154648 377 Gene3D G3DSA:3.40.640.10 1 245 4.6E-93 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_17415 0eb2aca2a959ffe0ecec34c92e154648 377 SUPERFAMILY SSF53383 16 376 9.38E-120 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_05605 3829c0054ea091f3dda93fefd1a3ff88 163 Gene3D G3DSA:3.30.70.990 12 101 7.5E-63 T 14-10-2018 IPR035570 UPF0234, N-terminal C2I25_05605 3829c0054ea091f3dda93fefd1a3ff88 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.975 T 14-10-2018 IPR007551 Protein of unknown function DUF520 C2I25_05605 3829c0054ea091f3dda93fefd1a3ff88 163 SUPERFAMILY SSF89963 91 163 1.41E-25 T 14-10-2018 IPR036183 YajQ-like superfamily C2I25_05605 3829c0054ea091f3dda93fefd1a3ff88 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 1.8E-62 T 14-10-2018 IPR007551 Protein of unknown function DUF520 C2I25_05605 3829c0054ea091f3dda93fefd1a3ff88 163 SUPERFAMILY SSF89963 6 90 1.07E-30 T 14-10-2018 IPR036183 YajQ-like superfamily C2I25_05605 3829c0054ea091f3dda93fefd1a3ff88 163 Gene3D G3DSA:3.30.70.860 6 163 7.5E-63 T 14-10-2018 IPR035571 UPF0234-like, C-terminal C2I25_19140 2e133c6278e3e33d2b49fb86c65d3aa7 490 PIRSF PIRSF005690 8 490 4.6E-137 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_19140 2e133c6278e3e33d2b49fb86c65d3aa7 490 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 22 479 1.3E-152 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 Pfam PF00248 Aldo/keto reductase family 30 265 5.7E-51 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_13745 b670ca18dead58de1069bd04b5612547 279 PRINTS PR00069 Aldo-keto reductase signature 99 117 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 PRINTS PR00069 Aldo-keto reductase signature 200 224 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 PRINTS PR00069 Aldo-keto reductase signature 129 146 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 PRINTS PR00069 Aldo-keto reductase signature 163 192 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 PRINTS PR00069 Aldo-keto reductase signature 39 63 2.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 233 248 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 PIRSF PIRSF000097 118 276 1.0E-52 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 PIRSF PIRSF000097 1 124 1.5E-40 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 SUPERFAMILY SSF51430 6 274 1.44E-95 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_13745 b670ca18dead58de1069bd04b5612547 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I25_13745 b670ca18dead58de1069bd04b5612547 279 Gene3D G3DSA:3.20.20.100 1 279 3.9E-126 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_12050 edfab0fac57d44908ca7f81e4ab4124f 437 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 129 272 4.3E-11 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like C2I25_05435 913654b4046f908e31ac86a9264f371a 514 Pfam PF13396 Phospholipase_D-nuclease N-terminal 57 93 1.6E-8 T 14-10-2018 IPR027379 Cardiolipin synthase N-terminal C2I25_05435 913654b4046f908e31ac86a9264f371a 514 SMART SM00155 249 276 8.4E-5 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 SMART SM00155 427 454 4.2E-7 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 Gene3D G3DSA:3.30.870.10 343 486 2.8E-30 T 14-10-2018 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 SUPERFAMILY SSF56024 301 500 2.92E-51 T 14-10-2018 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 43 514 1.6E-187 T 14-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 SUPERFAMILY SSF56024 144 344 1.19E-49 T 14-10-2018 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 Gene3D G3DSA:3.30.870.10 145 333 4.9E-47 T 14-10-2018 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 Pfam PF13091 PLD-like domain 167 309 6.2E-11 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 Pfam PF13091 PLD-like domain 356 480 2.4E-28 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_05435 913654b4046f908e31ac86a9264f371a 514 Hamap MF_01916 Cardiolipin synthase. 45 514 43.927 T 14-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 C2I25_05415 297b356c08adce3c6e918e61b1ea8dd9 297 Pfam PF13743 Thioredoxin 25 219 3.6E-73 T 14-10-2018 C2I25_05415 297b356c08adce3c6e918e61b1ea8dd9 297 SUPERFAMILY SSF52833 22 227 1.15E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_05415 297b356c08adce3c6e918e61b1ea8dd9 297 Gene3D G3DSA:1.10.472.60 62 188 3.3E-23 T 14-10-2018 C2I25_05415 297b356c08adce3c6e918e61b1ea8dd9 297 Gene3D G3DSA:3.40.30.10 27 213 3.3E-23 T 14-10-2018 C2I25_22700 24a376ca9975eabf07dcfb256367a79b 336 Gene3D G3DSA:3.20.20.100 2 322 6.4E-65 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_22700 24a376ca9975eabf07dcfb256367a79b 336 Pfam PF00248 Aldo/keto reductase family 8 321 1.1E-52 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_22700 24a376ca9975eabf07dcfb256367a79b 336 SUPERFAMILY SSF51430 7 328 7.86E-63 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_06330 3567a2268a72eda0c3e08855b584f3dd 208 Pfam PF01810 LysE type translocator 14 206 2.6E-40 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_06330 3567a2268a72eda0c3e08855b584f3dd 208 PIRSF PIRSF006324 1 208 1.9E-59 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_07400 9672939ca6def47b25a033b469fd6916 400 SUPERFAMILY SSF103473 13 390 2.35E-63 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_07400 9672939ca6def47b25a033b469fd6916 400 Gene3D G3DSA:1.20.1250.20 10 387 3.4E-57 T 14-10-2018 C2I25_07400 9672939ca6def47b25a033b469fd6916 400 Pfam PF03209 PUCC protein 276 396 3.4E-5 T 14-10-2018 IPR004896 PucC-related C2I25_07400 9672939ca6def47b25a033b469fd6916 400 Pfam PF07690 Major Facilitator Superfamily 20 239 3.4E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 Pfam PF13353 4Fe-4S single cluster domain 21 128 5.6E-9 T 14-10-2018 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 338 6.4E-117 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 SUPERFAMILY SSF102114 7 282 9.55E-77 T 14-10-2018 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 SMART SM00729 14 222 1.6E-8 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 Gene3D G3DSA:3.20.20.70 4 338 3.9E-103 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 338 40.101 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 Pfam PF06463 Molybdenum Cofactor Synthesis C 191 316 2.3E-37 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I25_21730 2342563a43b323462dd5da46f74cff5d 338 Pfam PF04055 Radical SAM superfamily 18 183 1.0E-27 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 SUPERFAMILY SSF52743 200 675 3.67E-85 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 221 232 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 Pfam PF02225 PA domain 461 537 6.8E-17 T 14-10-2018 IPR003137 PA domain C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 Pfam PF05922 Peptidase inhibitor I9 87 183 5.7E-8 T 14-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 216 235 6.3E-20 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 293 306 6.3E-20 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 614 630 6.3E-20 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 615 625 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 Pfam PF00082 Subtilase family 216 665 1.4E-66 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 297 307 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 Gene3D G3DSA:3.50.30.30 444 546 5.7E-33 T 14-10-2018 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 SUPERFAMILY SSF52025 457 549 1.11E-16 T 14-10-2018 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 Pfam PF06280 Fn3-like domain 736 809 3.3E-6 T 14-10-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 SUPERFAMILY SSF63446 1320 1375 6.54E-7 T 14-10-2018 IPR036439 Dockerin domain superfamily GO:0000272 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 PIRSF PIRSF037844 1 1407 0.0 T 14-10-2018 IPR017292 Peptidase S8A, Vpr C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 Gene3D G3DSA:2.60.40.4130 1230 1384 1.8E-13 T 14-10-2018 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 Gene3D G3DSA:3.40.50.200 547 678 5.7E-29 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_14815 dcbe7d458dec47d9d89cd380216829d8 1407 Gene3D G3DSA:3.40.50.200 189 443 4.8E-54 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_17100 b76d6a2decd423050587a56d92908978 637 PIRSF PIRSF018968 1 636 5.1E-100 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_17100 b76d6a2decd423050587a56d92908978 637 Pfam PF02687 FtsX-like permease family 84 178 1.5E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_01120 a8eb2289f4ff7ba0f0d38030fa745bbc 269 SUPERFAMILY SSF51658 18 265 1.87E-31 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily C2I25_01120 a8eb2289f4ff7ba0f0d38030fa745bbc 269 Gene3D G3DSA:3.20.20.150 2 266 8.1E-43 T 14-10-2018 C2I25_01120 a8eb2289f4ff7ba0f0d38030fa745bbc 269 Pfam PF01261 Xylose isomerase-like TIM barrel 46 221 8.0E-18 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain C2I25_18125 d0efbc984391133db5643e6d1a5c98f4 232 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 130 227 1.7E-17 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 C2I25_18125 d0efbc984391133db5643e6d1a5c98f4 232 Gene3D G3DSA:2.60.120.620 36 228 2.2E-69 T 14-10-2018 C2I25_18125 d0efbc984391133db5643e6d1a5c98f4 232 SMART SM00702 55 227 9.9E-46 T 14-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 SUPERFAMILY SSF49401 486 579 1.32E-5 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 1935 2028 9.6E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 346 437 1.0E-13 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 743 836 1.3E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 478 564 1.5E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 1006 1096 1.9E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 2067 2162 1.9E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 1405 1499 1.3E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 873 963 3.5E-8 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 1269 1366 5.0E-10 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 1671 1766 1.9E-14 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 610 704 9.3E-13 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 1803 1898 2.6E-11 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 1138 1232 5.4E-15 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Pfam PF01345 Domain of unknown function DUF11 2331 2428 1.1E-9 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2067 2119 2.7E-16 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1935 1987 2.5E-16 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1671 1723 3.5E-19 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1539 1591 1.2E-16 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1271 1322 6.2E-15 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1803 1854 3.8E-16 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2333 2384 3.4E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1139 1191 2.2E-20 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2199 2250 5.0E-14 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 347 399 2.6E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 479 531 9.3E-20 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 611 663 1.3E-19 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 743 795 4.2E-19 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1406 1458 3.0E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 875 927 1.6E-17 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1007 1058 9.2E-18 T 14-10-2018 IPR001434 Domain of unknown function DUF11 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Gene3D G3DSA:2.60.40.740 1400 1530 9.9E-6 T 14-10-2018 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Gene3D G3DSA:2.60.40.740 341 447 1.6E-7 T 14-10-2018 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Gene3D G3DSA:2.60.40.740 1134 1277 1.2E-5 T 14-10-2018 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Gene3D G3DSA:2.60.40.740 996 1111 3.8E-5 T 14-10-2018 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 Gene3D G3DSA:2.60.40.740 465 604 5.0E-7 T 14-10-2018 C2I25_21850 bed624fd9d6011b024f67464a4252ccd 2490 SUPERFAMILY SSF49401 355 447 1.54E-5 T 14-10-2018 IPR008966 Adhesion domain superfamily C2I25_24560 afc6c0eb02c6a8c92e3362f948a67dd0 160 Pfam PF11188 Protein of unknown function (DUF2975) 32 160 3.6E-40 T 14-10-2018 IPR021354 Protein of unknown function DUF2975 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 1.5E-50 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 SMART SM00363 2 59 1.5E-16 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 Gene3D G3DSA:3.30.70.1560 123 215 9.2E-56 T 14-10-2018 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 Gene3D G3DSA:3.10.290.10 1 63 2.6E-23 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 Pfam PF00849 RNA pseudouridylate synthase 62 196 6.0E-24 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 Gene3D G3DSA:3.30.70.580 64 223 9.2E-56 T 14-10-2018 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 SUPERFAMILY SSF55120 61 230 1.15E-44 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 Pfam PF01479 S4 domain 2 48 3.1E-17 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_04040 c0f9e4d5628186bcf41217cb10f65a94 242 SUPERFAMILY SSF55174 2 67 2.35E-17 T 14-10-2018 C2I25_23250 3b53cbe19a658c50e71978acf36ddcd0 275 Pfam PF04231 Endonuclease I 59 268 8.1E-45 T 14-10-2018 IPR007346 Endonuclease I GO:0004518 C2I25_23250 3b53cbe19a658c50e71978acf36ddcd0 275 SUPERFAMILY SSF54060 57 268 8.0E-60 T 14-10-2018 C2I25_21060 bf54d93b6b48f39c7eae062b7f32ccec 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 259 4.4E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_21060 bf54d93b6b48f39c7eae062b7f32ccec 264 SUPERFAMILY SSF161098 70 256 2.88E-34 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_21060 bf54d93b6b48f39c7eae062b7f32ccec 264 Gene3D G3DSA:1.10.3720.10 64 264 2.0E-32 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_21060 bf54d93b6b48f39c7eae062b7f32ccec 264 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 17 264 6.5E-92 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 C2I25_01635 e0461af336ae75ed5b69f9e33cf85031 153 PRINTS PR00502 NUDIX hydrolase family signature 44 58 4.4E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_01635 e0461af336ae75ed5b69f9e33cf85031 153 PRINTS PR00502 NUDIX hydrolase family signature 58 73 4.4E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_01635 e0461af336ae75ed5b69f9e33cf85031 153 Gene3D G3DSA:3.90.79.10 1 145 1.9E-40 T 14-10-2018 C2I25_01635 e0461af336ae75ed5b69f9e33cf85031 153 SUPERFAMILY SSF55811 4 147 3.67E-34 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_01635 e0461af336ae75ed5b69f9e33cf85031 153 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_01635 e0461af336ae75ed5b69f9e33cf85031 153 Pfam PF00293 NUDIX domain 22 141 4.7E-22 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_24350 45a93d9e0590b9f50873913d14124849 483 SMART SM00345 17 76 2.1E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_24350 45a93d9e0590b9f50873913d14124849 483 Gene3D G3DSA:3.90.1150.10 113 475 8.6E-104 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_24350 45a93d9e0590b9f50873913d14124849 483 Gene3D G3DSA:1.10.10.10 3 77 6.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24350 45a93d9e0590b9f50873913d14124849 483 Pfam PF00155 Aminotransferase class I and II 128 471 2.5E-33 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_24350 45a93d9e0590b9f50873913d14124849 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.7E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_24350 45a93d9e0590b9f50873913d14124849 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.7E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_24350 45a93d9e0590b9f50873913d14124849 483 Gene3D G3DSA:3.40.640.10 152 372 8.6E-104 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_24350 45a93d9e0590b9f50873913d14124849 483 SUPERFAMILY SSF53383 111 475 9.84E-94 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_24350 45a93d9e0590b9f50873913d14124849 483 SUPERFAMILY SSF46785 6 79 1.85E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_24350 45a93d9e0590b9f50873913d14124849 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.8E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_02465 cf51656e85dfcaaf3b3aea83a185af07 228 Gene3D G3DSA:3.30.240.20 170 228 4.4E-19 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_02465 cf51656e85dfcaaf3b3aea83a185af07 228 Gene3D G3DSA:3.30.240.20 80 156 3.0E-25 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_02465 cf51656e85dfcaaf3b3aea83a185af07 228 Pfam PF04239 Protein of unknown function (DUF421) 88 205 1.3E-31 T 14-10-2018 IPR007353 Protein of unknown function DUF421 C2I25_10325 9b7cd2f91f49551104c1591c8b6c8ddd 372 Gene3D G3DSA:3.10.180.10 4 172 7.6E-55 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_10325 9b7cd2f91f49551104c1591c8b6c8ddd 372 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 25 153 3.7E-6 T 14-10-2018 C2I25_10325 9b7cd2f91f49551104c1591c8b6c8ddd 372 SUPERFAMILY SSF54593 12 359 3.67E-91 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_10325 9b7cd2f91f49551104c1591c8b6c8ddd 372 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 21 372 1.9E-146 T 14-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 C2I25_10325 9b7cd2f91f49551104c1591c8b6c8ddd 372 Gene3D G3DSA:3.10.180.10 175 372 1.9E-83 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_10325 9b7cd2f91f49551104c1591c8b6c8ddd 372 PIRSF PIRSF009283 7 372 4.2E-141 T 14-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 C2I25_10325 9b7cd2f91f49551104c1591c8b6c8ddd 372 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 179 326 9.4E-18 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Pfam PF13429 Tetratricopeptide repeat 219 400 4.9E-8 T 14-10-2018 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SUPERFAMILY SSF48452 34 199 1.42E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Gene3D G3DSA:1.25.40.10 170 419 3.2E-42 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Pfam PF14559 Tetratricopeptide repeat 49 104 4.1E-6 T 14-10-2018 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Pfam PF13176 Tetratricopeptide repeat 140 163 0.0084 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Pfam PF13176 Tetratricopeptide repeat 174 201 1.0E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Gene3D G3DSA:1.25.40.10 3 166 3.0E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SUPERFAMILY SSF48452 176 408 4.55E-28 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 339 372 14.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 373 406 47.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 134 167 41.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 237 270 14.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 170 203 2.5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_03805 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 271 304 4.1E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_11915 996322509d2cd913ab402f209ded75a8 59 SUPERFAMILY SSF53098 1 55 1.5E-5 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_11915 996322509d2cd913ab402f209ded75a8 59 Pfam PF13333 Integrase core domain 2 57 3.2E-14 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 C2I25_07280 6ee65d6cc4c9e5b4d56d49c824bd0083 93 PIRSF PIRSF029962 1 93 9.7E-48 T 14-10-2018 IPR016941 Uncharacterised conserved protein UCP029962 C2I25_07280 6ee65d6cc4c9e5b4d56d49c824bd0083 93 Pfam PF06803 Protein of unknown function (DUF1232) 36 71 3.0E-11 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 C2I25_16085 f1eac589e7f34d4e0db5f60de7dddede 267 Pfam PF01513 ATP-NAD kinase 39 252 2.1E-16 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I25_16085 f1eac589e7f34d4e0db5f60de7dddede 267 Gene3D G3DSA:3.40.50.10330 39 267 7.8E-72 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 C2I25_16085 f1eac589e7f34d4e0db5f60de7dddede 267 Hamap MF_00361 NAD kinase [nadK]. 5 264 20.08 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I25_16085 f1eac589e7f34d4e0db5f60de7dddede 267 Gene3D G3DSA:2.60.200.30 109 245 7.8E-72 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I25_16085 f1eac589e7f34d4e0db5f60de7dddede 267 SUPERFAMILY SSF111331 6 266 7.03E-56 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily C2I25_17755 cd8cd3a7b33401d3816e1b362c213b14 399 PIRSF PIRSF029895 1 398 1.6E-171 T 14-10-2018 IPR010690 Putative stage IV sporulation YqfD C2I25_17755 cd8cd3a7b33401d3816e1b362c213b14 399 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 387 3.8E-148 T 14-10-2018 IPR010690 Putative stage IV sporulation YqfD C2I25_17755 cd8cd3a7b33401d3816e1b362c213b14 399 Pfam PF06898 Putative stage IV sporulation protein YqfD 9 385 1.5E-120 T 14-10-2018 IPR010690 Putative stage IV sporulation YqfD C2I25_17765 964cf4a626a02ecd66f04461637c5f97 714 Pfam PF07698 7TM receptor with intracellular HD hydrolase 277 476 6.7E-44 T 14-10-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain C2I25_17765 964cf4a626a02ecd66f04461637c5f97 714 SMART SM00471 497 653 3.8E-10 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_17765 964cf4a626a02ecd66f04461637c5f97 714 SUPERFAMILY SSF109604 500 678 5.34E-13 T 14-10-2018 C2I25_17765 964cf4a626a02ecd66f04461637c5f97 714 Pfam PF01966 HD domain 501 643 5.1E-17 T 14-10-2018 IPR006674 HD domain C2I25_17765 964cf4a626a02ecd66f04461637c5f97 714 TIGRFAM TIGR00277 HDIG: HDIG domain 498 596 2.4E-26 T 14-10-2018 IPR006675 HDIG domain C2I25_17765 964cf4a626a02ecd66f04461637c5f97 714 Gene3D G3DSA:1.10.3210.10 473 670 7.5E-25 T 14-10-2018 C2I25_17765 964cf4a626a02ecd66f04461637c5f97 714 Pfam PF07697 7TM-HD extracellular 51 270 2.4E-33 T 14-10-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain C2I25_17250 776736599046f212f2bbacfa320de03b 423 Pfam PF13393 Histidyl-tRNA synthetase 8 313 4.1E-45 T 14-10-2018 C2I25_17250 776736599046f212f2bbacfa320de03b 423 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 2.3E-155 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 C2I25_17250 776736599046f212f2bbacfa320de03b 423 Gene3D G3DSA:3.30.930.10 1 324 6.7E-115 T 14-10-2018 C2I25_17250 776736599046f212f2bbacfa320de03b 423 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 33.73 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 C2I25_17250 776736599046f212f2bbacfa320de03b 423 SUPERFAMILY SSF55681 3 318 7.85E-96 T 14-10-2018 C2I25_17250 776736599046f212f2bbacfa320de03b 423 PIRSF PIRSF001549 1 422 7.5E-122 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 C2I25_17250 776736599046f212f2bbacfa320de03b 423 SUPERFAMILY SSF52954 329 421 3.62E-26 T 14-10-2018 C2I25_17250 776736599046f212f2bbacfa320de03b 423 Gene3D G3DSA:3.40.50.800 327 423 1.3E-26 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily C2I25_17250 776736599046f212f2bbacfa320de03b 423 Pfam PF03129 Anticodon binding domain 331 420 5.1E-18 T 14-10-2018 IPR004154 Anticodon-binding C2I25_25790 c8ffbcdeb6c51d1d6e4f6b851fe398ac 145 PRINTS PR00502 NUDIX hydrolase family signature 59 74 4.1E-10 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_25790 c8ffbcdeb6c51d1d6e4f6b851fe398ac 145 PRINTS PR00502 NUDIX hydrolase family signature 45 59 4.1E-10 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_25790 c8ffbcdeb6c51d1d6e4f6b851fe398ac 145 Pfam PF00293 NUDIX domain 22 131 1.1E-17 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_25790 c8ffbcdeb6c51d1d6e4f6b851fe398ac 145 Gene3D G3DSA:3.90.79.10 1 145 1.4E-45 T 14-10-2018 C2I25_25790 c8ffbcdeb6c51d1d6e4f6b851fe398ac 145 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_25790 c8ffbcdeb6c51d1d6e4f6b851fe398ac 145 SUPERFAMILY SSF55811 15 142 5.01E-29 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_05505 8513c9e501dcc6a55bc3be8cc0787222 126 Pfam PF13038 Domain of unknown function (DUF3899) 35 122 5.7E-22 T 14-10-2018 IPR025007 Domain of unknown function DUF3899 C2I25_03435 ef4890884397ffe2aebe7399e27c49c6 266 SUPERFAMILY SSF53448 12 230 1.78E-55 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_03435 ef4890884397ffe2aebe7399e27c49c6 266 Gene3D G3DSA:3.90.550.10 3 258 5.4E-59 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_03435 ef4890884397ffe2aebe7399e27c49c6 266 Pfam PF00535 Glycosyl transferase family 2 15 139 1.0E-33 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_24250 1b50ef2c13a2a5dc0bd2aa32d99ce51a 245 Pfam PF02146 Sir2 family 25 196 7.7E-51 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 C2I25_24250 1b50ef2c13a2a5dc0bd2aa32d99ce51a 245 Gene3D G3DSA:3.40.50.1220 16 239 1.9E-71 T 14-10-2018 C2I25_24250 1b50ef2c13a2a5dc0bd2aa32d99ce51a 245 Gene3D G3DSA:3.30.1600.10 34 168 1.9E-71 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily C2I25_24250 1b50ef2c13a2a5dc0bd2aa32d99ce51a 245 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 9 242 62.373 T 14-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 C2I25_24250 1b50ef2c13a2a5dc0bd2aa32d99ce51a 245 SUPERFAMILY SSF52467 5 241 9.35E-76 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_25075 d7c5130aa12e841f09cd8b0336119c24 132 SUPERFAMILY SSF54637 3 126 8.71E-29 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_25075 d7c5130aa12e841f09cd8b0336119c24 132 Pfam PF07977 FabA-like domain 7 123 3.2E-15 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I25_25075 d7c5130aa12e841f09cd8b0336119c24 132 Gene3D G3DSA:3.10.129.10 1 131 7.2E-32 T 14-10-2018 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 442 6.1E-158 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 97 112 - T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 PRINTS PR00175 Sodium/alanine symporter signature 215 234 5.2E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 PRINTS PR00175 Sodium/alanine symporter signature 351 373 5.2E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 PRINTS PR00175 Sodium/alanine symporter signature 187 205 5.2E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 PRINTS PR00175 Sodium/alanine symporter signature 97 119 5.2E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 PRINTS PR00175 Sodium/alanine symporter signature 411 431 5.2E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 PRINTS PR00175 Sodium/alanine symporter signature 306 324 5.2E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13775 68dfdbea9a52cf30d7a4d8dd50775f9d 480 Pfam PF01235 Sodium:alanine symporter family 59 454 9.0E-164 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 Pfam PF00005 ABC transporter 334 469 3.6E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 Pfam PF16326 ABC transporter C-terminal domain 559 624 5.3E-18 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 Gene3D G3DSA:1.10.287.380 551 629 1.8E-11 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 SUPERFAMILY SSF52540 4 240 4.17E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 SUPERFAMILY SSF52540 313 516 9.28E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 Gene3D G3DSA:3.40.50.300 282 550 1.6E-63 T 14-10-2018 C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 Pfam PF00005 ABC transporter 20 187 4.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 Gene3D G3DSA:3.40.50.300 1 281 6.2E-73 T 14-10-2018 C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 Pfam PF12848 ABC transporter 226 302 1.2E-16 T 14-10-2018 IPR032781 ABC-transporter extension domain C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 SMART SM00382 343 514 4.4E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_00545 1d801e3cb75c2ff4f2229c5f87ab1ba6 631 SMART SM00382 28 231 3.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_23340 cd3c71aadb0b691a05ed62a1b0f445c0 299 SUPERFAMILY SSF52540 3 219 1.07E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23340 cd3c71aadb0b691a05ed62a1b0f445c0 299 Pfam PF13732 Domain of unknown function (DUF4162) 211 298 5.6E-8 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 C2I25_23340 cd3c71aadb0b691a05ed62a1b0f445c0 299 Pfam PF00005 ABC transporter 19 157 2.0E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_23340 cd3c71aadb0b691a05ed62a1b0f445c0 299 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_23340 cd3c71aadb0b691a05ed62a1b0f445c0 299 SMART SM00382 27 204 3.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_23340 cd3c71aadb0b691a05ed62a1b0f445c0 299 Gene3D G3DSA:3.40.50.300 1 234 2.0E-68 T 14-10-2018 C2I25_24540 07307f99d2115c4634e7da1f6cd468b9 128 Gene3D G3DSA:3.10.450.590 23 126 2.6E-14 T 14-10-2018 C2I25_24540 07307f99d2115c4634e7da1f6cd468b9 128 Pfam PF13026 Protein of unknown function (DUF3887) 37 125 1.4E-19 T 14-10-2018 IPR024981 Domain of unknown function DUF3887 KEGG: 00983+3.1.1.1|MetaCyc: PWY-6303|MetaCyc: PWY-6857 C2I25_16095 295c669840b080dc2887301e49c92805 131 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 2 122 2.2E-50 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_16095 295c669840b080dc2887301e49c92805 131 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 30 113 1.7E-29 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_16095 295c669840b080dc2887301e49c92805 131 PIRSF PIRSF021377 1 130 7.2E-55 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_04365 8d660be1405b7ef24ab132d1123e64f9 209 Gene3D G3DSA:3.40.50.880 1 207 6.0E-71 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_04365 8d660be1405b7ef24ab132d1123e64f9 209 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 198 35.91 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 C2I25_04365 8d660be1405b7ef24ab132d1123e64f9 209 PIRSF PIRSF000495 1 201 2.8E-70 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 C2I25_04365 8d660be1405b7ef24ab132d1123e64f9 209 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 196 2.8E-72 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 C2I25_04365 8d660be1405b7ef24ab132d1123e64f9 209 Pfam PF00117 Glutamine amidotransferase class-I 4 195 3.0E-20 T 14-10-2018 IPR017926 Glutamine amidotransferase C2I25_04365 8d660be1405b7ef24ab132d1123e64f9 209 SUPERFAMILY SSF52317 2 198 1.81E-55 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 SMART SM00966 8 52 1.1E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 Gene3D G3DSA:3.30.450.40 56 178 5.1E-45 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 3.1E-94 T 14-10-2018 IPR014213 Sporulation stage V, protein T C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 4.3E-45 T 14-10-2018 IPR039472 Sporulation stage V protein T, GAF domain C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 Gene3D G3DSA:2.10.260.10 1 49 3.8E-24 T 14-10-2018 C2I25_11340 6eb3963e4ca89528853eb2867aab7767 178 PIRSF PIRSF026579 1 178 2.9E-96 T 14-10-2018 IPR014213 Sporulation stage V, protein T C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 Gene3D G3DSA:3.40.50.150 74 265 6.3E-60 T 14-10-2018 C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 SUPERFAMILY SSF53335 75 248 1.05E-44 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 Pfam PF03705 CheR methyltransferase, all-alpha domain 10 62 6.3E-9 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 SMART SM00138 9 263 4.1E-79 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 PRINTS PR00996 Glutamate methyltransferase family signature 68 80 2.7E-37 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 PRINTS PR00996 Glutamate methyltransferase family signature 204 218 2.7E-37 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 PRINTS PR00996 Glutamate methyltransferase family signature 106 126 2.7E-37 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 PRINTS PR00996 Glutamate methyltransferase family signature 223 246 2.7E-37 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 PRINTS PR00996 Glutamate methyltransferase family signature 31 44 2.7E-37 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 PRINTS PR00996 Glutamate methyltransferase family signature 138 154 2.7E-37 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 Pfam PF01739 CheR methyltransferase, SAM binding domain 75 250 7.4E-56 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal C2I25_03195 23ee288ddfe7a80e5ca15aeeb44b561f 265 SUPERFAMILY SSF47757 9 74 5.36E-10 T 14-10-2018 C2I25_02250 e1d003997d7c2a32825fd91aec0df3a0 194 SUPERFAMILY SSF46689 13 72 3.99E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_02250 e1d003997d7c2a32825fd91aec0df3a0 194 Gene3D G3DSA:1.10.357.10 3 189 1.5E-38 T 14-10-2018 C2I25_02250 e1d003997d7c2a32825fd91aec0df3a0 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 8.4E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 SUPERFAMILY SSF55486 256 565 4.4E-105 T 14-10-2018 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 84 134 4.0E-14 T 14-10-2018 IPR011096 FTP domain C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 Gene3D G3DSA:1.10.390.10 405 565 2.6E-74 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 355 375 4.9E-31 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 391 407 4.9E-31 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 480 496 4.9E-31 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 412 423 4.9E-31 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 Gene3D G3DSA:3.10.450.40 142 225 2.1E-5 T 14-10-2018 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 257 400 1.1E-52 T 14-10-2018 IPR013856 Peptidase M4 domain GO:0004222 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 Gene3D G3DSA:3.10.450.490 62 141 6.1E-6 T 14-10-2018 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 403 565 1.4E-64 T 14-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 Pfam PF03413 Peptidase propeptide and YPEB domain 151 220 2.3E-8 T 14-10-2018 IPR025711 PepSY domain C2I25_08485 2076c310d440648aad2eab5902fc4f14 566 Gene3D G3DSA:3.10.170.10 255 404 2.4E-66 T 14-10-2018 C2I25_17275 da9cca3ad7ba8155a6771dfc1aa45498 213 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 81 4.1E-45 T 14-10-2018 IPR014243 Transcription factor, RsfA C2I25_17275 da9cca3ad7ba8155a6771dfc1aa45498 213 Pfam PF13921 Myb-like DNA-binding domain 8 62 6.5E-6 T 14-10-2018 C2I25_01920 96997db6a3fc36518d46392f6bade293 467 PIRSF PIRSF006446 1 467 3.2E-179 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I25_01920 96997db6a3fc36518d46392f6bade293 467 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 441 3.4E-170 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I25_26280 b963bf80c82bc4371f788589f23c6370 268 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 268 5.3E-53 T 14-10-2018 IPR003797 DegV C2I25_26280 b963bf80c82bc4371f788589f23c6370 268 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 7 268 2.0E-57 T 14-10-2018 IPR003797 DegV C2I25_26280 b963bf80c82bc4371f788589f23c6370 268 Gene3D G3DSA:3.40.50.10170 1 147 3.3E-32 T 14-10-2018 C2I25_26280 b963bf80c82bc4371f788589f23c6370 268 Gene3D G3DSA:3.30.1180.10 149 268 1.4E-21 T 14-10-2018 C2I25_26280 b963bf80c82bc4371f788589f23c6370 268 SUPERFAMILY SSF82549 1 268 6.54E-62 T 14-10-2018 C2I25_14270 92e9c9651e88b606b1ce5c5335ba00e5 103 PIRSF PIRSF012565 1 103 7.7E-51 T 14-10-2018 IPR009370 Protein of unknown function DUF1027 C2I25_14270 92e9c9651e88b606b1ce5c5335ba00e5 103 Gene3D G3DSA:3.50.4.20 2 103 5.6E-43 T 14-10-2018 IPR038141 YutD-like superfamily C2I25_14270 92e9c9651e88b606b1ce5c5335ba00e5 103 Pfam PF06265 Protein of unknown function (DUF1027) 16 99 2.1E-38 T 14-10-2018 IPR009370 Protein of unknown function DUF1027 C2I25_05655 2670d8e281115467afde675caee9cae2 396 Pfam PF00202 Aminotransferase class-III 15 395 4.6E-133 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_05655 2670d8e281115467afde675caee9cae2 396 PIRSF PIRSF000521 175 396 8.5E-31 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_05655 2670d8e281115467afde675caee9cae2 396 PIRSF PIRSF000521 2 160 4.8E-8 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_05655 2670d8e281115467afde675caee9cae2 396 Gene3D G3DSA:3.40.640.10 58 306 4.5E-155 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_05655 2670d8e281115467afde675caee9cae2 396 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 4 395 2.1E-164 T 14-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I25_05655 2670d8e281115467afde675caee9cae2 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_05655 2670d8e281115467afde675caee9cae2 396 Gene3D G3DSA:3.90.1150.10 23 385 4.5E-155 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_05655 2670d8e281115467afde675caee9cae2 396 SUPERFAMILY SSF53383 3 395 1.67E-124 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_05655 2670d8e281115467afde675caee9cae2 396 Hamap MF_01689 Ornithine aminotransferase [rocD]. 4 396 68.036 T 14-10-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 C2I25_14840 f5efb479a11004c6cae328deb2efac07 476 Gene3D G3DSA:3.40.50.2000 250 458 2.2E-184 T 14-10-2018 C2I25_14840 f5efb479a11004c6cae328deb2efac07 476 Hamap MF_00484 Glycogen synthase [glgA]. 1 474 46.514 T 14-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 C2I25_14840 f5efb479a11004c6cae328deb2efac07 476 SUPERFAMILY SSF53756 3 476 2.69E-133 T 14-10-2018 C2I25_14840 f5efb479a11004c6cae328deb2efac07 476 Pfam PF08323 Starch synthase catalytic domain 2 237 4.9E-83 T 14-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 C2I25_14840 f5efb479a11004c6cae328deb2efac07 476 Pfam PF00534 Glycosyl transferases group 1 287 437 6.0E-19 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 C2I25_14840 f5efb479a11004c6cae328deb2efac07 476 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 2 474 1.2E-178 T 14-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 C2I25_14840 f5efb479a11004c6cae328deb2efac07 476 Gene3D G3DSA:3.40.50.2000 3 472 2.2E-184 T 14-10-2018 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 Gene3D G3DSA:1.10.275.10 12 145 4.6E-58 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 12 473 1.2E-233 T 14-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 ProSitePatterns PS00163 Fumarate lyases signature. 323 332 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 PRINTS PR00145 Argininosuccinate lyase family signature 140 162 2.6E-7 T 14-10-2018 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 PRINTS PR00145 Argininosuccinate lyase family signature 181 201 2.6E-7 T 14-10-2018 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 PRINTS PR00145 Argininosuccinate lyase family signature 323 339 2.6E-7 T 14-10-2018 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 Gene3D G3DSA:1.10.40.30 414 465 2.3E-22 T 14-10-2018 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 3.5E-32 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 PRINTS PR00149 Fumarate lyase superfamily signature 186 204 3.5E-32 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 PRINTS PR00149 Fumarate lyase superfamily signature 277 304 3.5E-32 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 PRINTS PR00149 Fumarate lyase superfamily signature 323 339 3.5E-32 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 SUPERFAMILY SSF48557 12 468 1.52E-148 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 Pfam PF10415 Fumarase C C-terminus 414 467 1.1E-20 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 Gene3D G3DSA:1.20.200.10 146 413 5.5E-114 T 14-10-2018 C2I25_02615 da3d6764d30f698297a4e52b9b0b7ef3 479 Pfam PF00206 Lyase 19 348 4.5E-110 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 192 402 6.1E-51 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 558 721 9.1E-48 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 409 2.3E-99 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Gene3D G3DSA:1.20.1640.10 229 426 3.3E-10 T 14-10-2018 C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 SUPERFAMILY SSF82866 213 414 7.19E-38 T 14-10-2018 C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 478 724 3.7E-67 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 449 735 25.878 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Pfam PF02355 Protein export membrane protein 242 406 1.6E-14 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Pfam PF02355 Protein export membrane protein 555 733 1.2E-62 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Gene3D G3DSA:1.20.1640.10 557 753 4.7E-11 T 14-10-2018 C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 PRINTS PR01755 Bacterial translocase SecF protein signature 476 491 3.6E-22 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 PRINTS PR01755 Bacterial translocase SecF protein signature 672 687 3.6E-22 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 PRINTS PR01755 Bacterial translocase SecF protein signature 636 654 3.6E-22 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 PRINTS PR01755 Bacterial translocase SecF protein signature 588 602 3.6E-22 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 423 32.38 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Gene3D G3DSA:3.30.70.3400 35 123 4.4E-23 T 14-10-2018 C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Pfam PF07549 SecD/SecF GG Motif 471 498 1.3E-7 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 Pfam PF07549 SecD/SecF GG Motif 30 51 0.017 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site C2I25_17215 524c58695f17873066b9c46578cfbc8b 754 SUPERFAMILY SSF82866 557 737 6.02E-37 T 14-10-2018 C2I25_01865 0beff3e16a333384caf8aa3a78d2bce4 333 SUPERFAMILY SSF52317 1 160 1.1E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_01865 0beff3e16a333384caf8aa3a78d2bce4 333 Gene3D G3DSA:3.40.50.10740 1 164 6.3E-63 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal C2I25_01865 0beff3e16a333384caf8aa3a78d2bce4 333 PIRSF PIRSF028757 1 333 4.7E-86 T 14-10-2018 IPR003507 Peptidase family S66 C2I25_01865 0beff3e16a333384caf8aa3a78d2bce4 333 SUPERFAMILY SSF141986 176 325 1.1E-41 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I25_01865 0beff3e16a333384caf8aa3a78d2bce4 333 Gene3D G3DSA:3.50.30.60 165 333 2.1E-63 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I25_01865 0beff3e16a333384caf8aa3a78d2bce4 333 Pfam PF02016 LD-carboxypeptidase 13 317 3.5E-70 T 14-10-2018 IPR003507 Peptidase family S66 C2I25_11790 17d491961a5a043593c979d73cd6c8e0 438 Gene3D G3DSA:3.30.310.160 223 359 1.9E-39 T 14-10-2018 C2I25_11790 17d491961a5a043593c979d73cd6c8e0 438 Gene3D G3DSA:3.10.450.310 201 406 1.9E-39 T 14-10-2018 C2I25_11790 17d491961a5a043593c979d73cd6c8e0 438 Pfam PF07435 YycH protein 4 414 1.2E-70 T 14-10-2018 IPR009996 Regulatory protein YycH C2I25_05395 f1c741d7c3f1ab28560fce7db4280132 212 Gene3D G3DSA:3.30.460.10 1 147 3.7E-51 T 14-10-2018 C2I25_05395 f1c741d7c3f1ab28560fce7db4280132 212 SMART SM00954 44 165 3.9E-38 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I25_05395 f1c741d7c3f1ab28560fce7db4280132 212 SUPERFAMILY SSF81301 3 198 8.83E-60 T 14-10-2018 C2I25_05395 f1c741d7c3f1ab28560fce7db4280132 212 Gene3D G3DSA:1.10.287.860 148 211 1.0E-28 T 14-10-2018 C2I25_05395 f1c741d7c3f1ab28560fce7db4280132 212 Pfam PF04607 Region found in RelA / SpoT proteins 44 162 1.4E-37 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I25_08155 7a198c7563a3673b580d02fdaa2e62c3 308 Gene3D G3DSA:3.40.50.2300 139 273 1.7E-92 T 14-10-2018 C2I25_08155 7a198c7563a3673b580d02fdaa2e62c3 308 SUPERFAMILY SSF53822 33 307 3.6E-91 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_08155 7a198c7563a3673b580d02fdaa2e62c3 308 Gene3D G3DSA:3.40.50.2300 44 292 1.7E-92 T 14-10-2018 C2I25_08155 7a198c7563a3673b580d02fdaa2e62c3 308 Pfam PF13407 Periplasmic binding protein domain 41 292 2.5E-66 T 14-10-2018 IPR025997 Periplasmic binding protein C2I25_12100 9894c15200e5b12af2dab5c6571fcf82 351 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 188 348 2.7E-44 T 14-10-2018 IPR000160 GGDEF domain C2I25_12100 9894c15200e5b12af2dab5c6571fcf82 351 Gene3D G3DSA:3.30.70.270 179 350 9.6E-48 T 14-10-2018 C2I25_12100 9894c15200e5b12af2dab5c6571fcf82 351 SMART SM00267 180 350 2.4E-45 T 14-10-2018 IPR000160 GGDEF domain C2I25_12100 9894c15200e5b12af2dab5c6571fcf82 351 Pfam PF00990 Diguanylate cyclase, GGDEF domain 191 346 8.5E-37 T 14-10-2018 IPR000160 GGDEF domain C2I25_12100 9894c15200e5b12af2dab5c6571fcf82 351 Pfam PF07694 5TMR of 5TMR-LYT 28 167 2.9E-12 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I25_12100 9894c15200e5b12af2dab5c6571fcf82 351 SUPERFAMILY SSF55073 196 348 1.57E-39 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_20760 7b802903bf1e5f9851155e5e1f6d9250 392 Pfam PF10720 Protein of unknown function (DUF2515) 51 381 1.3E-127 T 14-10-2018 IPR019658 Protein of unknown function DUF2515 C2I25_12900 3f0505b80afcaf148bc7c1051551b752 444 PIRSF PIRSF002808 6 443 3.0E-126 T 14-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 C2I25_12900 3f0505b80afcaf148bc7c1051551b752 444 Gene3D G3DSA:1.20.1250.20 19 226 2.2E-49 T 14-10-2018 C2I25_12900 3f0505b80afcaf148bc7c1051551b752 444 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 415 4.0E-126 T 14-10-2018 C2I25_12900 3f0505b80afcaf148bc7c1051551b752 444 Pfam PF07690 Major Facilitator Superfamily 35 397 1.3E-47 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_12900 3f0505b80afcaf148bc7c1051551b752 444 SUPERFAMILY SSF103473 13 439 4.19E-80 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_12900 3f0505b80afcaf148bc7c1051551b752 444 ProSitePatterns PS00942 glpT family of transporters signature. 150 166 - T 14-10-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site Reactome: R-HSA-3229133|Reactome: R-HSA-70263 C2I25_12900 3f0505b80afcaf148bc7c1051551b752 444 Gene3D G3DSA:1.20.1250.20 241 441 8.9E-50 T 14-10-2018 C2I25_16900 ea1338bdd0c8375f497e7c770c72c651 204 Gene3D G3DSA:2.30.29.50 12 115 8.1E-47 T 14-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily C2I25_16900 ea1338bdd0c8375f497e7c770c72c651 204 Gene3D G3DSA:1.10.287.210 116 204 4.4E-36 T 14-10-2018 C2I25_16900 ea1338bdd0c8375f497e7c770c72c651 204 Pfam PF11724 YvbH-like oligomerisation region 144 204 1.1E-26 T 14-10-2018 IPR021722 Uncharacterised domain YvbH-like, oligomerisation domain C2I25_16900 ea1338bdd0c8375f497e7c770c72c651 204 SUPERFAMILY SSF50729 14 203 3.01E-68 T 14-10-2018 C2I25_16900 ea1338bdd0c8375f497e7c770c72c651 204 Pfam PF08000 Bacterial PH domain 11 131 2.8E-37 T 14-10-2018 IPR012544 Bacterial Pleckstrin homology domain C2I25_14490 03420f391583e78e0045dd2bb8729f30 293 SUPERFAMILY SSF46785 63 110 6.3E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_14490 03420f391583e78e0045dd2bb8729f30 293 Gene3D G3DSA:1.10.10.10 16 133 5.2E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_14490 03420f391583e78e0045dd2bb8729f30 293 Pfam PF13730 Helix-turn-helix domain 34 92 8.5E-12 T 14-10-2018 C2I25_06335 b21813ffb5ca2dae49054e887685ca5b 110 SUPERFAMILY SSF55331 1 108 6.23E-35 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_06335 b21813ffb5ca2dae49054e887685ca5b 110 Gene3D G3DSA:3.30.429.10 1 108 1.1E-37 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_06335 b21813ffb5ca2dae49054e887685ca5b 110 Pfam PF08921 Domain of unknown function (DUF1904) 1 107 8.7E-31 T 14-10-2018 IPR015017 Protein of unknown function DUF1904 C2I25_16315 2f1099f2c6053642ed66da984cd80a84 372 Pfam PF01594 AI-2E family transporter 12 354 1.7E-69 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like C2I25_16315 2f1099f2c6053642ed66da984cd80a84 372 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 359 1.8E-124 T 14-10-2018 IPR014227 Putative transport protein YtvI-like C2I25_17240 3be8987a2522f36eb8d2a51c5d446d5a 146 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.493 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 C2I25_17240 3be8987a2522f36eb8d2a51c5d446d5a 146 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 1.6E-58 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 C2I25_17240 3be8987a2522f36eb8d2a51c5d446d5a 146 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.4E-60 T 14-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 C2I25_17240 3be8987a2522f36eb8d2a51c5d446d5a 146 Gene3D G3DSA:3.50.80.10 1 146 3.7E-60 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily C2I25_17240 3be8987a2522f36eb8d2a51c5d446d5a 146 SUPERFAMILY SSF69500 1 144 4.58E-60 T 14-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily C2I25_12340 a9210886f8977faa903d2120e6fe4c6b 328 Pfam PF02016 LD-carboxypeptidase 12 314 9.7E-76 T 14-10-2018 IPR003507 Peptidase family S66 C2I25_12340 a9210886f8977faa903d2120e6fe4c6b 328 SUPERFAMILY SSF141986 166 318 1.57E-35 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I25_12340 a9210886f8977faa903d2120e6fe4c6b 328 PIRSF PIRSF028757 1 328 1.3E-80 T 14-10-2018 IPR003507 Peptidase family S66 C2I25_12340 a9210886f8977faa903d2120e6fe4c6b 328 SUPERFAMILY SSF52317 2 165 4.3E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_12340 a9210886f8977faa903d2120e6fe4c6b 328 Gene3D G3DSA:3.40.50.10740 1 158 1.5E-61 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal C2I25_12340 a9210886f8977faa903d2120e6fe4c6b 328 Gene3D G3DSA:3.50.30.60 159 328 1.3E-62 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I25_19465 5cbfc69fc0f979b6438c307263ff3394 129 Pfam PF11033 Competence protein J (ComJ) 2 126 8.7E-52 T 14-10-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ C2I25_19465 5cbfc69fc0f979b6438c307263ff3394 129 ProDom PD081734 COMPETENCE J NIN DNA-ENTRY MEMBRANE INHIBITOR NUCLEASE 3 106 2.0E-54 T 14-10-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ C2I25_19465 5cbfc69fc0f979b6438c307263ff3394 129 Gene3D G3DSA:2.60.34.30 1 124 6.0E-40 T 14-10-2018 IPR038691 DNA-entry nuclease inhibitor, ComJ superfamily C2I25_26815 5c3a8fe6874ceb06254d121e17aaf5f7 256 Gene3D G3DSA:3.40.50.300 1 243 1.5E-64 T 14-10-2018 C2I25_26815 5c3a8fe6874ceb06254d121e17aaf5f7 256 SUPERFAMILY SSF52540 3 224 8.35E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_26815 5c3a8fe6874ceb06254d121e17aaf5f7 256 SMART SM00382 31 226 1.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26815 5c3a8fe6874ceb06254d121e17aaf5f7 256 Pfam PF00005 ABC transporter 24 170 9.0E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 Gene3D G3DSA:3.90.78.10 217 301 1.9E-34 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 Pfam PF01565 FAD binding domain 35 163 4.7E-23 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 Gene3D G3DSA:3.30.43.10 1 88 2.7E-26 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 4.0E-97 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 2.3E-28 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 301 89.731 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 SUPERFAMILY SSF56194 197 300 4.58E-37 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 Gene3D G3DSA:3.30.465.10 89 216 4.2E-45 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_19950 9206dae72ee18164bf11852992c4c64a 301 SUPERFAMILY SSF56176 14 193 1.76E-40 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 SUPERFAMILY SSF52540 154 396 2.17E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 SUPERFAMILY SSF46689 366 457 7.53E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 366 375 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 Gene3D G3DSA:1.10.8.60 324 390 3.6E-26 T 14-10-2018 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 SMART SM00382 174 317 4.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 SUPERFAMILY SSF55785 9 114 9.77E-13 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 439 3.0E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 439 459 3.0E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 Pfam PF02954 Bacterial regulatory protein, Fis family 416 456 5.0E-14 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 Pfam PF08448 PAS fold 18 118 7.0E-7 T 14-10-2018 IPR013656 PAS fold-4 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 Gene3D G3DSA:3.40.50.300 139 323 1.5E-60 T 14-10-2018 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 Gene3D G3DSA:1.10.10.60 391 459 4.0E-16 T 14-10-2018 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 Pfam PF00158 Sigma-54 interaction domain 154 319 1.7E-62 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 178 191 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 Gene3D G3DSA:3.30.450.20 6 119 2.0E-13 T 14-10-2018 C2I25_28450 d42ecece32ca9cb22e750bb45354cde1 461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 125 8.9E-7 T 14-10-2018 IPR000014 PAS domain C2I25_19845 c5fc60b3ff52f1292c7ba6df47978e13 188 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 C2I25_19845 c5fc60b3ff52f1292c7ba6df47978e13 188 Gene3D G3DSA:3.40.50.150 1 187 1.4E-56 T 14-10-2018 C2I25_19845 c5fc60b3ff52f1292c7ba6df47978e13 188 PIRSF PIRSF004553 1 184 2.3E-50 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 C2I25_19845 c5fc60b3ff52f1292c7ba6df47978e13 188 SUPERFAMILY SSF53335 1 181 1.32E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_19845 c5fc60b3ff52f1292c7ba6df47978e13 188 Pfam PF03602 Conserved hypothetical protein 95 1 181 5.7E-58 T 14-10-2018 C2I25_19845 c5fc60b3ff52f1292c7ba6df47978e13 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 3.8E-53 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 C2I25_03390 c51e76608d51dc5ebb2b4e79a30b1eee 290 SUPERFAMILY SSF74650 4 289 1.38E-57 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 C2I25_03390 c51e76608d51dc5ebb2b4e79a30b1eee 290 Gene3D G3DSA:2.70.98.10 2 290 1.7E-107 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 C2I25_03390 c51e76608d51dc5ebb2b4e79a30b1eee 290 Pfam PF01263 Aldose 1-epimerase 2 282 3.1E-34 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 C2I25_14615 41605fde073a71b1472006ae3cec448c 83 ProDom PD062625 YUGE 1 83 6.0E-43 T 14-10-2018 IPR015053 Protein of unknown function DUF1871 C2I25_14615 41605fde073a71b1472006ae3cec448c 83 SUPERFAMILY SSF116922 3 78 2.09E-27 T 14-10-2018 IPR023162 Apc36109-like domain superfamily C2I25_14615 41605fde073a71b1472006ae3cec448c 83 Pfam PF08958 Domain of unknown function (DUF1871) 6 82 2.0E-37 T 14-10-2018 IPR015053 Protein of unknown function DUF1871 C2I25_14615 41605fde073a71b1472006ae3cec448c 83 Gene3D G3DSA:1.10.340.20 2 83 1.0E-29 T 14-10-2018 IPR023162 Apc36109-like domain superfamily C2I25_10790 7b49d40d808fd501ef5e1b0ae4f87292 237 SMART SM00646 115 226 7.4E-32 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_10790 7b49d40d808fd501ef5e1b0ae4f87292 237 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 40 228 1.7E-83 T 14-10-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD MetaCyc: PWY-7883 C2I25_10790 7b49d40d808fd501ef5e1b0ae4f87292 237 Gene3D G3DSA:3.40.630.40 38 235 2.9E-54 T 14-10-2018 C2I25_10790 7b49d40d808fd501ef5e1b0ae4f87292 237 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 42 226 5.6E-47 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_10790 7b49d40d808fd501ef5e1b0ae4f87292 237 SUPERFAMILY SSF53187 40 231 5.34E-52 T 14-10-2018 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 SUPERFAMILY SSF55174 1 59 6.48E-12 T 14-10-2018 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 SMART SM00363 1 59 4.3E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 Pfam PF01479 S4 domain 1 45 3.7E-11 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 Gene3D G3DSA:3.30.70.580 62 230 1.2E-55 T 14-10-2018 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 SUPERFAMILY SSF55120 46 235 6.84E-43 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 Pfam PF00849 RNA pseudouridylate synthase 62 195 1.0E-18 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 227 2.5E-45 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 Gene3D G3DSA:3.10.290.10 1 58 1.1E-16 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_15725 0426907fe61b8804615531a0d3eaede0 242 Gene3D G3DSA:3.30.70.1560 129 212 1.2E-55 T 14-10-2018 C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 Gene3D G3DSA:3.40.140.20 378 511 1.0E-56 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 SUPERFAMILY SSF53927 206 511 6.72E-130 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 Gene3D G3DSA:3.40.50.1380 1 198 5.5E-87 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 SMART SM00798 134 446 7.9E-203 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 Gene3D G3DSA:3.40.140.20 203 360 6.0E-62 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 SUPERFAMILY SSF52335 2 194 1.83E-69 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 PIRSF PIRSF000414 1 511 3.0E-216 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 511 45.924 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 SMART SM00851 14 129 5.8E-56 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 444 2.7E-124 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 Pfam PF02142 MGS-like domain 14 129 6.8E-27 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I25_09890 a0e32c1df38e3ffcafe882dab0cebd66 511 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 511 9.5E-245 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_08790 114bf5d002d319c527b0cc9de9f1cb1f 258 SUPERFAMILY SSF53955 61 239 2.22E-69 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily C2I25_08790 114bf5d002d319c527b0cc9de9f1cb1f 258 Gene3D G3DSA:1.10.3810.10 61 238 1.3E-78 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_08790 114bf5d002d319c527b0cc9de9f1cb1f 258 Pfam PF00912 Transglycosylase 60 217 2.2E-60 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_03415 ff631a5795557502a8abf5cf995a869d 286 Gene3D G3DSA:3.40.630.30 2 129 2.0E-16 T 14-10-2018 C2I25_03415 ff631a5795557502a8abf5cf995a869d 286 Gene3D G3DSA:3.40.630.90 130 286 6.8E-10 T 14-10-2018 C2I25_03415 ff631a5795557502a8abf5cf995a869d 286 Pfam PF13673 Acetyltransferase (GNAT) domain 33 123 5.6E-10 T 14-10-2018 IPR000182 GNAT domain C2I25_03415 ff631a5795557502a8abf5cf995a869d 286 SUPERFAMILY SSF55729 6 265 3.37E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 43.073 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 Gene3D G3DSA:3.90.230.10 1 248 3.1E-109 T 14-10-2018 C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 SUPERFAMILY SSF55920 1 246 4.97E-93 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 Pfam PF00557 Metallopeptidase family M24 12 239 8.4E-58 T 14-10-2018 IPR000994 Peptidase M24 C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.8E-103 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 3.5E-23 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 3.5E-23 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 3.5E-23 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_10860 0c0b59c0a98903b50aa889eaba7c5bfb 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 3.5E-23 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_04950 093ce1e26d9089d43b8ddcf95fdea759 201 Pfam PF07853 Protein of unknown function (DUF1648) 10 56 3.8E-16 T 14-10-2018 IPR012867 Domain of unknown function DUF1648 C2I25_16235 3727bd0645a48c3d54bf843cd4b59661 227 SUPERFAMILY SSF56281 1 220 2.1E-41 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_16235 3727bd0645a48c3d54bf843cd4b59661 227 SMART SM00849 7 193 5.1E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_16235 3727bd0645a48c3d54bf843cd4b59661 227 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 227 38.425 T 14-10-2018 IPR022877 Protein of unknown funcion UPF0173 C2I25_16235 3727bd0645a48c3d54bf843cd4b59661 227 Gene3D G3DSA:3.60.15.10 1 227 4.7E-77 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_16235 3727bd0645a48c3d54bf843cd4b59661 227 Pfam PF13483 Beta-lactamase superfamily domain 2 193 9.4E-28 T 14-10-2018 C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 Pfam PF00294 pfkB family carbohydrate kinase 1 286 3.2E-69 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 Hamap MF_01987 Ribokinase [rbsK]. 2 293 24.79 T 14-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 291 3.2E-100 T 14-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 SUPERFAMILY SSF53613 4 292 5.61E-77 T 14-10-2018 IPR029056 Ribokinase-like C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 Gene3D G3DSA:3.40.1190.20 2 293 1.4E-90 T 14-10-2018 IPR029056 Ribokinase-like C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 PRINTS PR00990 Ribokinase signature 33 52 5.5E-33 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 PRINTS PR00990 Ribokinase signature 172 187 5.5E-33 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 PRINTS PR00990 Ribokinase signature 6 27 5.5E-33 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 PRINTS PR00990 Ribokinase signature 104 117 5.5E-33 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 PRINTS PR00990 Ribokinase signature 209 220 5.5E-33 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I25_08175 ebc0365437a431aba33a571aa131b2ba 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 238 251 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I25_19090 8db145a7de6970741cc54bf3a0e68c2f 146 SMART SM00387 35 140 2.1E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_19090 8db145a7de6970741cc54bf3a0e68c2f 146 Gene3D G3DSA:3.30.565.10 1 142 4.2E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_19090 8db145a7de6970741cc54bf3a0e68c2f 146 SUPERFAMILY SSF55874 28 135 1.7E-22 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_19090 8db145a7de6970741cc54bf3a0e68c2f 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 136 1.3E-70 T 14-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 C2I25_19090 8db145a7de6970741cc54bf3a0e68c2f 146 Pfam PF13581 Histidine kinase-like ATPase domain 10 136 1.9E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_19090 8db145a7de6970741cc54bf3a0e68c2f 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 34.938 T 14-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 C2I25_23545 c9b7f45b43d50fbc96048726d605a818 223 Gene3D G3DSA:3.40.50.300 1 223 1.4E-69 T 14-10-2018 C2I25_23545 c9b7f45b43d50fbc96048726d605a818 223 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_23545 c9b7f45b43d50fbc96048726d605a818 223 SMART SM00382 33 220 1.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_23545 c9b7f45b43d50fbc96048726d605a818 223 SUPERFAMILY SSF52540 4 222 6.36E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23545 c9b7f45b43d50fbc96048726d605a818 223 Pfam PF00005 ABC transporter 24 173 2.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_24685 c0fd98ade4c12825d07867daa839b9a7 310 Gene3D G3DSA:3.40.50.1360 58 310 2.5E-70 T 14-10-2018 C2I25_24685 c0fd98ade4c12825d07867daa839b9a7 310 Gene3D G3DSA:1.10.10.10 1 54 7.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24685 c0fd98ade4c12825d07867daa839b9a7 310 SUPERFAMILY SSF100950 62 306 1.02E-61 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_24685 c0fd98ade4c12825d07867daa839b9a7 310 Pfam PF04198 Putative sugar-binding domain 62 304 6.6E-65 T 14-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 C2I25_22435 33c93445b094d7ae166868876f1ec57f 472 Pfam PF00324 Amino acid permease 23 433 1.4E-102 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I25_22435 33c93445b094d7ae166868876f1ec57f 472 Gene3D G3DSA:1.20.1740.10 14 469 1.7E-60 T 14-10-2018 C2I25_22435 33c93445b094d7ae166868876f1ec57f 472 ProSitePatterns PS00218 Amino acid permeases signature. 48 78 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I25_22435 33c93445b094d7ae166868876f1ec57f 472 PIRSF PIRSF006060 7 471 6.2E-67 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_05960 b3e692a5bdeeb400462883cbbdb97041 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 47 151 1.7E-10 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I25_05960 b3e692a5bdeeb400462883cbbdb97041 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 327 7.5E-30 T 14-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 C2I25_05960 b3e692a5bdeeb400462883cbbdb97041 329 Gene3D G3DSA:3.30.390.50 243 329 9.5E-31 T 14-10-2018 C2I25_05960 b3e692a5bdeeb400462883cbbdb97041 329 SUPERFAMILY SSF82649 243 329 5.75E-27 T 14-10-2018 C2I25_05960 b3e692a5bdeeb400462883cbbdb97041 329 Gene3D G3DSA:3.30.930.10 3 242 1.5E-79 T 14-10-2018 C2I25_05960 b3e692a5bdeeb400462883cbbdb97041 329 SUPERFAMILY SSF55681 2 241 1.49E-81 T 14-10-2018 C2I25_05960 b3e692a5bdeeb400462883cbbdb97041 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 323 1.9E-130 T 14-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 C2I25_12265 5641df0c918a48e63170dcb895e3fee9 270 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_12265 5641df0c918a48e63170dcb895e3fee9 270 Pfam PF00005 ABC transporter 20 167 1.7E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_12265 5641df0c918a48e63170dcb895e3fee9 270 SUPERFAMILY SSF52540 4 232 9.61E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12265 5641df0c918a48e63170dcb895e3fee9 270 Gene3D G3DSA:3.40.50.300 3 255 3.8E-68 T 14-10-2018 C2I25_12265 5641df0c918a48e63170dcb895e3fee9 270 SMART SM00382 28 217 1.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_13460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Gene3D G3DSA:1.10.10.10 215 309 2.6E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_13460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 3.0E-37 T 14-10-2018 IPR039518 WhiA, LAGLIDADG-like domain C2I25_13460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.2E-35 T 14-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal C2I25_13460 fc7bcac20d2cd0a0c85fc7cce1985948 316 SUPERFAMILY SSF55608 120 221 2.89E-20 T 14-10-2018 IPR027434 Homing endonuclease C2I25_13460 fc7bcac20d2cd0a0c85fc7cce1985948 316 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 2.6E-137 T 14-10-2018 IPR033981 Sporulation regulator WhiA-like C2I25_13460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Gene3D G3DSA:3.10.28.10 1 214 4.4E-68 T 14-10-2018 IPR027434 Homing endonuclease C2I25_13460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 18 103 4.0E-37 T 14-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain C2I25_13460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 35.693 T 14-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 Gene3D G3DSA:1.10.3210.10 319 473 2.6E-19 T 14-10-2018 C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 SUPERFAMILY SSF54791 209 305 3.42E-16 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 TIGRFAM TIGR00277 HDIG: HDIG domain 333 410 3.1E-26 T 14-10-2018 IPR006675 HDIG domain C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 Pfam PF00013 KH domain 214 268 3.5E-6 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 Pfam PF01966 HD domain 338 429 4.1E-19 T 14-10-2018 IPR006674 HD domain C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 9 521 5.6E-247 T 14-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 SUPERFAMILY SSF109604 317 468 1.59E-30 T 14-10-2018 C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 SMART SM00322 209 276 1.1E-6 T 14-10-2018 IPR004087 K Homology domain GO:0003676 C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 SMART SM00471 333 439 4.7E-14 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 Pfam PF12072 Domain of unknown function (DUF3552) 7 206 4.0E-77 T 14-10-2018 IPR022711 Ribonuclease Y, N-terminal C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 Hamap MF_00335 Ribonuclease Y [rny]. 6 521 25.926 T 14-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 C2I25_20625 7d3c6501fab5089433d7f6cbcb7df1c4 521 Gene3D G3DSA:3.30.1370.10 208 304 1.1E-8 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I25_13445 3e162f3621902e7f561b36351ae7a61c 152 Gene3D G3DSA:3.90.79.10 1 152 1.7E-41 T 14-10-2018 C2I25_13445 3e162f3621902e7f561b36351ae7a61c 152 PRINTS PR00502 NUDIX hydrolase family signature 26 40 9.1E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_13445 3e162f3621902e7f561b36351ae7a61c 152 PRINTS PR00502 NUDIX hydrolase family signature 40 55 9.1E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_13445 3e162f3621902e7f561b36351ae7a61c 152 Pfam PF00293 NUDIX domain 4 124 1.5E-16 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_13445 3e162f3621902e7f561b36351ae7a61c 152 SUPERFAMILY SSF55811 3 128 3.01E-29 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_22945 0a8c9dcb1136fbbc03dcd62153ca2544 58 Pfam PF06906 Protein of unknown function (DUF1272) 2 56 3.9E-26 T 14-10-2018 IPR010696 Protein of unknown function DUF1272 C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 Gene3D G3DSA:3.40.50.720 1 246 1.0E-81 T 14-10-2018 C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 SUPERFAMILY SSF51735 4 246 2.82E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 6.1E-68 T 14-10-2018 C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22395 bd1b77165fb55bd72329a29bf9c13e8b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 Gene3D G3DSA:3.40.430.10 136 361 1.8E-77 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 Gene3D G3DSA:3.40.140.10 1 135 1.8E-42 T 14-10-2018 C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 Pfam PF01872 RibD C-terminal domain 147 354 8.9E-59 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 SUPERFAMILY SSF53927 3 145 2.34E-44 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 PIRSF PIRSF006769 1 362 1.3E-133 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 355 1.3E-124 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 88 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 3.3E-21 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 145 357 2.0E-72 T 14-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 C2I25_18900 621efdb4ee11b9e108bb5fd77595443c 370 SUPERFAMILY SSF53597 147 356 6.64E-62 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I25_12120 278f9208885cb524f7979d2fe77698fd 208 SUPERFAMILY SSF52218 1 208 5.64E-47 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_12120 278f9208885cb524f7979d2fe77698fd 208 Pfam PF02525 Flavodoxin-like fold 3 203 3.5E-41 T 14-10-2018 IPR003680 Flavodoxin-like fold C2I25_12120 278f9208885cb524f7979d2fe77698fd 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 28.916 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 C2I25_12120 278f9208885cb524f7979d2fe77698fd 208 Gene3D G3DSA:3.40.50.360 1 208 5.5E-60 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_19015 29b0063f167d7d599718c48a0ed80c65 394 Hamap MF_00740 Phosphopentomutase [deoB]. 4 389 57.431 T 14-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I25_19015 29b0063f167d7d599718c48a0ed80c65 394 SUPERFAMILY SSF53649 3 392 1.31E-79 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_19015 29b0063f167d7d599718c48a0ed80c65 394 SUPERFAMILY SSF143856 101 217 6.41E-53 T 14-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I25_19015 29b0063f167d7d599718c48a0ed80c65 394 Pfam PF01676 Metalloenzyme superfamily 5 380 3.6E-43 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 C2I25_19015 29b0063f167d7d599718c48a0ed80c65 394 Gene3D G3DSA:3.30.70.1250 99 217 1.1E-179 T 14-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I25_19015 29b0063f167d7d599718c48a0ed80c65 394 PIRSF PIRSF001491 3 393 1.2E-170 T 14-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I25_19015 29b0063f167d7d599718c48a0ed80c65 394 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 387 4.3E-207 T 14-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I25_19015 29b0063f167d7d599718c48a0ed80c65 394 Gene3D G3DSA:3.40.720.10 5 389 1.1E-179 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_09180 90623a0e3a202fa1a5cc38a700916d87 506 Pfam PF05681 Fumarate hydratase (Fumerase) 6 282 6.7E-71 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 C2I25_09180 90623a0e3a202fa1a5cc38a700916d87 506 Pfam PF05683 Fumarase C-terminus 289 488 1.4E-63 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 C2I25_09180 90623a0e3a202fa1a5cc38a700916d87 506 PIRSF PIRSF001394 1 505 1.3E-200 T 14-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 C2I25_09180 90623a0e3a202fa1a5cc38a700916d87 506 SUPERFAMILY SSF117457 316 486 5.23E-53 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 C2I25_09180 90623a0e3a202fa1a5cc38a700916d87 506 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 325 486 1.3E-51 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 C2I25_09180 90623a0e3a202fa1a5cc38a700916d87 506 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 5 280 1.6E-60 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 C2I25_09180 90623a0e3a202fa1a5cc38a700916d87 506 Gene3D G3DSA:3.20.130.10 299 487 1.3E-65 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 C2I25_04865 0f763ae0de64b66598b7ff44570b517f 61 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_04865 0f763ae0de64b66598b7ff44570b517f 61 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 1.8E-22 T 14-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I25_04865 0f763ae0de64b66598b7ff44570b517f 61 Gene3D G3DSA:1.10.8.910 5 61 7.5E-29 T 14-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I25_04865 0f763ae0de64b66598b7ff44570b517f 61 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_15590 1abcc9e87e18cd103a898d39add0f266 374 Gene3D G3DSA:3.40.50.1820 1 374 5.5E-121 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_15590 1abcc9e87e18cd103a898d39add0f266 374 PIRSF PIRSF000443 1 374 6.1E-122 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 C2I25_15590 1abcc9e87e18cd103a898d39add0f266 374 SUPERFAMILY SSF53474 4 368 1.25E-68 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_15590 1abcc9e87e18cd103a898d39add0f266 374 Pfam PF00561 alpha/beta hydrolase fold 40 327 5.7E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_15590 1abcc9e87e18cd103a898d39add0f266 374 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 1 367 23.835 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 C2I25_18015 b09ebda820ba3819c903488185b81ea5 610 Gene3D G3DSA:3.20.20.220 309 598 1.5E-56 T 14-10-2018 C2I25_18015 b09ebda820ba3819c903488185b81ea5 610 Pfam PF02219 Methylenetetrahydrofolate reductase 316 575 8.5E-31 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I25_18015 b09ebda820ba3819c903488185b81ea5 610 SUPERFAMILY SSF51730 316 600 3.53E-71 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like C2I25_18015 b09ebda820ba3819c903488185b81ea5 610 SUPERFAMILY SSF82282 3 360 1.09E-93 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I25_18015 b09ebda820ba3819c903488185b81ea5 610 Pfam PF02574 Homocysteine S-methyltransferase 12 281 3.3E-50 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 C2I25_18015 b09ebda820ba3819c903488185b81ea5 610 Gene3D G3DSA:3.20.20.330 1 293 1.4E-82 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I25_06970 3640d57f00018093b4bc02765699e43d 495 Pfam PF04055 Radical SAM superfamily 178 350 1.4E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_06970 3640d57f00018093b4bc02765699e43d 495 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 89 489 3.5E-148 T 14-10-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ C2I25_06970 3640d57f00018093b4bc02765699e43d 495 Gene3D G3DSA:3.80.30.20 132 485 3.8E-66 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I25_06970 3640d57f00018093b4bc02765699e43d 495 SMART SM00729 170 394 1.9E-46 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_06970 3640d57f00018093b4bc02765699e43d 495 SUPERFAMILY SSF102114 163 477 6.15E-70 T 14-10-2018 C2I25_10920 1eb48b86857d2cdaf3958ecbace7a682 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 7.9E-54 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 C2I25_10920 1eb48b86857d2cdaf3958ecbace7a682 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10920 1eb48b86857d2cdaf3958ecbace7a682 122 Gene3D G3DSA:2.40.150.20 1 122 4.4E-53 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_10920 1eb48b86857d2cdaf3958ecbace7a682 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.791 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 C2I25_10920 1eb48b86857d2cdaf3958ecbace7a682 122 SMART SM01374 1 122 1.9E-86 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 C2I25_10920 1eb48b86857d2cdaf3958ecbace7a682 122 SUPERFAMILY SSF50193 1 122 3.01E-50 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_10920 1eb48b86857d2cdaf3958ecbace7a682 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.8E-57 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 C2I25_02665 a5a66ced019e9a61b07a01503995b5dd 162 SUPERFAMILY SSF88659 88 157 2.06E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_02665 a5a66ced019e9a61b07a01503995b5dd 162 SUPERFAMILY SSF88946 2 73 1.57E-17 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_02665 a5a66ced019e9a61b07a01503995b5dd 162 Pfam PF08281 Sigma-70, region 4 101 151 9.7E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_02665 a5a66ced019e9a61b07a01503995b5dd 162 Gene3D G3DSA:1.10.10.10 95 158 6.8E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02665 a5a66ced019e9a61b07a01503995b5dd 162 Pfam PF04542 Sigma-70 region 2 2 68 1.5E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_02665 a5a66ced019e9a61b07a01503995b5dd 162 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 155 4.6E-26 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_02665 a5a66ced019e9a61b07a01503995b5dd 162 Gene3D G3DSA:1.10.1740.10 1 94 6.5E-20 T 14-10-2018 C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 SUPERFAMILY SSF51735 13 254 2.51E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.4E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.4E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 2.4E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 254 4.4E-50 T 14-10-2018 C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 4.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 4.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 4.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 4.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 4.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 4.8E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_16175 cc12922faf0410c551f9619acd62cf38 263 Gene3D G3DSA:3.40.50.720 12 263 3.3E-72 T 14-10-2018 C2I25_24045 6999b58ae16107f0d4e723fc4fa86836 197 Pfam PF03992 Antibiotic biosynthesis monooxygenase 22 91 3.9E-7 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I25_24045 6999b58ae16107f0d4e723fc4fa86836 197 Gene3D G3DSA:3.30.70.100 21 116 8.6E-9 T 14-10-2018 C2I25_24045 6999b58ae16107f0d4e723fc4fa86836 197 SUPERFAMILY SSF54909 15 113 2.77E-18 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_04595 89feb4e395885e9a77b89b728e798353 184 Gene3D G3DSA:3.40.50.850 2 184 4.3E-51 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_04595 89feb4e395885e9a77b89b728e798353 184 Pfam PF00857 Isochorismatase family 6 178 6.5E-34 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_04595 89feb4e395885e9a77b89b728e798353 184 SUPERFAMILY SSF52499 3 182 1.7E-44 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_03145 3c8df21b2a4f106e4e8fde3b1f3bb624 137 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 89 130 9.8E-10 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I25_03145 3c8df21b2a4f106e4e8fde3b1f3bb624 137 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 2 136 6.6E-39 T 14-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 C2I25_03145 3c8df21b2a4f106e4e8fde3b1f3bb624 137 Pfam PF00460 Flagella basal body rod protein 5 32 4.9E-5 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I25_23870 8fafe2796cfbaf5ff3fe32ad9e092a24 618 Pfam PF07993 Male sterility protein 6 239 1.4E-40 T 14-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 C2I25_23870 8fafe2796cfbaf5ff3fe32ad9e092a24 618 Pfam PF12697 Alpha/beta hydrolase family 382 607 1.1E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_23870 8fafe2796cfbaf5ff3fe32ad9e092a24 618 SUPERFAMILY SSF51735 1 294 1.77E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_23870 8fafe2796cfbaf5ff3fe32ad9e092a24 618 Gene3D G3DSA:3.40.50.720 1 314 1.3E-40 T 14-10-2018 C2I25_23870 8fafe2796cfbaf5ff3fe32ad9e092a24 618 Gene3D G3DSA:3.40.50.1820 352 615 6.5E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_23870 8fafe2796cfbaf5ff3fe32ad9e092a24 618 SUPERFAMILY SSF53474 373 611 3.85E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 SMART SM00382 492 673 0.4 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 SMART SM00382 829 1278 2.1 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 Gene3D G3DSA:3.40.50.300 1082 1320 5.1E-30 T 14-10-2018 C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 Gene3D G3DSA:3.40.50.300 435 735 3.4E-83 T 14-10-2018 C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 Pfam PF01580 FtsK/SpoIIIE family 486 676 4.7E-29 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 Pfam PF01580 FtsK/SpoIIIE family 807 1001 9.1E-25 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 Pfam PF01580 FtsK/SpoIIIE family 1103 1253 2.2E-16 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 9 1313 0.0 T 14-10-2018 IPR023839 Firmicutes EssC, C-terminal C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 SUPERFAMILY SSF52540 773 1016 1.29E-18 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 Gene3D G3DSA:3.40.50.300 778 1073 6.4E-62 T 14-10-2018 C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 SUPERFAMILY SSF52540 451 711 5.87E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_00435 85eda9b8fdc9211a91258edbe5d12c45 1342 SUPERFAMILY SSF52540 1095 1250 1.25E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 Gene3D G3DSA:3.30.450.20 346 475 1.3E-19 T 14-10-2018 C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 SUPERFAMILY SSF55073 487 643 2.2E-42 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 Pfam PF00563 EAL domain 658 893 7.9E-70 T 14-10-2018 IPR001633 EAL domain C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 Gene3D G3DSA:3.20.20.450 655 907 1.3E-93 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 355 477 8.9E-18 T 14-10-2018 IPR000014 PAS domain C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 SMART SM00267 470 642 9.4E-49 T 14-10-2018 IPR000160 GGDEF domain C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 SUPERFAMILY SSF55785 345 468 3.84E-17 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 479 640 4.9E-36 T 14-10-2018 IPR000160 GGDEF domain C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 Pfam PF08448 PAS fold 368 471 9.2E-10 T 14-10-2018 IPR013656 PAS fold-4 C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 SUPERFAMILY SSF141868 657 905 1.31E-83 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 SMART SM00091 358 424 1.0E-6 T 14-10-2018 IPR000014 PAS domain C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 Pfam PF00990 Diguanylate cyclase, GGDEF domain 481 636 1.9E-41 T 14-10-2018 IPR000160 GGDEF domain C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 SMART SM00052 652 898 6.2E-109 T 14-10-2018 IPR001633 EAL domain C2I25_20785 d67c413865211ebe8a41a49dd36fc85c 909 Gene3D G3DSA:3.30.70.270 476 654 4.5E-51 T 14-10-2018 C2I25_00250 c4049d5e866d7fd1e666e00a2f6419b4 218 Pfam PF03006 Haemolysin-III related 13 206 1.9E-42 T 14-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 C2I25_00250 c4049d5e866d7fd1e666e00a2f6419b4 218 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 14 214 9.3E-74 T 14-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 C2I25_09840 16e6d4e427896d9b20ba36bdff456547 398 Pfam PF07537 CamS sex pheromone cAM373 precursor 57 390 1.3E-112 T 14-10-2018 IPR011426 CamS sex pheromone cAM373 C2I25_09840 16e6d4e427896d9b20ba36bdff456547 398 PIRSF PIRSF012509 1 398 3.2E-149 T 14-10-2018 IPR011426 CamS sex pheromone cAM373 C2I25_09840 16e6d4e427896d9b20ba36bdff456547 398 Gene3D G3DSA:3.10.570.10 53 398 3.4E-118 T 14-10-2018 C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 SUPERFAMILY SSF52540 1 240 1.4E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 Pfam PF00005 ABC transporter 22 169 1.6E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 Pfam PF09383 NIL domain 263 326 2.5E-19 T 14-10-2018 IPR018449 NIL domain C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 SMART SM00382 30 226 4.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 Gene3D G3DSA:3.30.70.260 233 336 3.6E-28 T 14-10-2018 C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 SUPERFAMILY SSF55021 252 332 4.12E-20 T 14-10-2018 C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 Gene3D G3DSA:3.40.50.300 1 232 2.3E-78 T 14-10-2018 C2I25_09810 adade2381b9a1414a75c33ccedaf46a1 339 SMART SM00930 260 334 7.4E-27 T 14-10-2018 IPR018449 NIL domain C2I25_01735 84b81428de121f8776a9b060cfd073a7 273 Gene3D G3DSA:3.20.20.370 24 261 1.4E-64 T 14-10-2018 C2I25_01735 84b81428de121f8776a9b060cfd073a7 273 Pfam PF01522 Polysaccharide deacetylase 64 170 1.1E-28 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_01735 84b81428de121f8776a9b060cfd073a7 273 SUPERFAMILY SSF88713 63 264 2.47E-55 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_16385 11a05e499e56ce90669c84012dfa95f3 200 SUPERFAMILY SSF52540 1 194 8.88E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16385 11a05e499e56ce90669c84012dfa95f3 200 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 199 29.866 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 C2I25_16385 11a05e499e56ce90669c84012dfa95f3 200 Pfam PF01121 Dephospho-CoA kinase 4 182 4.5E-69 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 C2I25_16385 11a05e499e56ce90669c84012dfa95f3 200 Gene3D G3DSA:3.40.50.300 1 199 2.0E-80 T 14-10-2018 C2I25_16385 11a05e499e56ce90669c84012dfa95f3 200 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 1.4E-69 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 C2I25_17925 67c83eb348e1b32c9da19f6ba73ce2b6 305 Gene3D G3DSA:3.40.190.10 34 286 5.2E-78 T 14-10-2018 C2I25_17925 67c83eb348e1b32c9da19f6ba73ce2b6 305 SUPERFAMILY SSF53850 32 301 4.11E-63 T 14-10-2018 C2I25_17925 67c83eb348e1b32c9da19f6ba73ce2b6 305 Gene3D G3DSA:3.40.190.10 113 249 5.2E-78 T 14-10-2018 C2I25_17925 67c83eb348e1b32c9da19f6ba73ce2b6 305 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 32 288 6.3E-80 T 14-10-2018 IPR011862 Phosphate binding protein GO:0042301 C2I25_17925 67c83eb348e1b32c9da19f6ba73ce2b6 305 Pfam PF12849 PBP superfamily domain 32 256 3.8E-22 T 14-10-2018 IPR024370 PBP domain C2I25_08905 857ee86c00797c996c3dacfea35dcd47 118 Pfam PF11023 Zinc-ribbon containing domain 4 114 4.3E-59 T 14-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 C2I25_08905 857ee86c00797c996c3dacfea35dcd47 118 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 4 114 3.0E-61 T 14-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 C2I25_08905 857ee86c00797c996c3dacfea35dcd47 118 Hamap MF_01502 UPF0295 protein . 2 116 37.405 T 14-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 SUPERFAMILY SSF46785 5 85 5.88E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 43 2.1E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.1E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 2.1E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.1E-19 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 Pfam PF01022 Bacterial regulatory protein, arsR family 17 62 5.4E-18 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 Gene3D G3DSA:1.10.10.10 2 90 1.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 34 52 - T 14-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 C2I25_23900 0cb638d0a847c2fc29c0864432e89b12 101 SMART SM00418 10 89 3.1E-30 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_18755 e4fbe7e88d939a6bc2e34f7f5a47c857 62 Pfam PF14164 YqzH-like protein 1 60 6.5E-23 T 14-10-2018 IPR025546 YqzH-like protein C2I25_24040 d5d7e840b910540890183ca883778784 613 Gene3D G3DSA:3.10.310.70 83 206 2.6E-81 T 14-10-2018 C2I25_24040 d5d7e840b910540890183ca883778784 613 Gene3D G3DSA:2.30.40.10 12 511 2.6E-81 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_24040 d5d7e840b910540890183ca883778784 613 SUPERFAMILY SSF51556 63 496 2.08E-43 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_24040 d5d7e840b910540890183ca883778784 613 Gene3D G3DSA:3.20.20.140 64 495 2.6E-81 T 14-10-2018 C2I25_24040 d5d7e840b910540890183ca883778784 613 SUPERFAMILY SSF51338 5 540 1.92E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_24040 d5d7e840b910540890183ca883778784 613 Pfam PF07969 Amidohydrolase family 54 536 3.1E-107 T 14-10-2018 IPR013108 Amidohydrolase 3 C2I25_17135 f34f1fbb741721defaf6e843e26ac30e 368 Gene3D G3DSA:3.40.50.10800 29 348 1.1E-81 T 14-10-2018 C2I25_17135 f34f1fbb741721defaf6e843e26ac30e 368 Gene3D G3DSA:3.40.50.10800 112 366 1.1E-81 T 14-10-2018 C2I25_17135 f34f1fbb741721defaf6e843e26ac30e 368 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 21 366 1.2E-116 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I25_17135 f34f1fbb741721defaf6e843e26ac30e 368 Hamap MF_00569 Quinolinate synthase A [nadA]. 22 367 56.788 T 14-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I25_17135 f34f1fbb741721defaf6e843e26ac30e 368 Pfam PF02445 Quinolinate synthetase A protein 29 366 9.0E-107 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I25_17135 f34f1fbb741721defaf6e843e26ac30e 368 SUPERFAMILY SSF142754 34 366 8.24E-98 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I25_17135 f34f1fbb741721defaf6e843e26ac30e 368 Gene3D G3DSA:3.40.50.10800 230 315 1.1E-81 T 14-10-2018 C2I25_28335 7a323e9cdd47660ee027911fe7eabb7c 283 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 161 182 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 C2I25_28335 7a323e9cdd47660ee027911fe7eabb7c 283 SUPERFAMILY SSF54534 124 222 2.81E-31 T 14-10-2018 C2I25_28335 7a323e9cdd47660ee027911fe7eabb7c 283 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 281 21.804 T 14-10-2018 IPR023059 Foldase protein PrsA GO:0003755 C2I25_28335 7a323e9cdd47660ee027911fe7eabb7c 283 SUPERFAMILY SSF109998 43 162 1.26E-12 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I25_28335 7a323e9cdd47660ee027911fe7eabb7c 283 Pfam PF13616 PPIC-type PPIASE domain 131 224 1.7E-27 T 14-10-2018 C2I25_28335 7a323e9cdd47660ee027911fe7eabb7c 283 Gene3D G3DSA:3.10.50.40 124 246 1.7E-35 T 14-10-2018 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 SUPERFAMILY SSF158472 194 245 2.48E-11 T 14-10-2018 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 Pfam PF00672 HAMP domain 194 242 3.6E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 SMART SM00387 367 480 1.2E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 Gene3D G3DSA:3.30.565.10 326 478 1.7E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 477 6.6E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 SMART SM00388 254 321 5.3E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 Gene3D G3DSA:1.10.287.130 250 320 3.8E-20 T 14-10-2018 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 319 8.6E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 SUPERFAMILY SSF55874 310 476 3.41E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 SMART SM00304 194 246 5.7E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 SUPERFAMILY SSF47384 241 321 3.73E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 3.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 477 3.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 3.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 3.4E-17 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_15930 f285d21c26ee61dd383e9b352d159e80 484 Gene3D G3DSA:1.20.1480.50 158 249 1.8E-16 T 14-10-2018 C2I25_18455 ea871f5e6fa722640f92538f1fc2ebca 432 Pfam PF05580 SpoIVB peptidase S55 209 417 4.1E-85 T 14-10-2018 IPR008763 Peptidase S55, SpoIVB C2I25_18455 ea871f5e6fa722640f92538f1fc2ebca 432 SMART SM00228 116 192 5.2E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_18455 ea871f5e6fa722640f92538f1fc2ebca 432 SUPERFAMILY SSF50494 354 416 7.63E-7 T 14-10-2018 IPR009003 Peptidase S1, PA clan C2I25_18455 ea871f5e6fa722640f92538f1fc2ebca 432 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 7 422 7.5E-182 T 14-10-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B C2I25_18455 ea871f5e6fa722640f92538f1fc2ebca 432 Gene3D G3DSA:2.30.42.10 140 218 2.0E-15 T 14-10-2018 C2I25_18455 ea871f5e6fa722640f92538f1fc2ebca 432 Pfam PF13180 PDZ domain 141 194 2.7E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_18455 ea871f5e6fa722640f92538f1fc2ebca 432 SUPERFAMILY SSF50156 143 228 5.39E-11 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I25_21390 2c036d8682e765f214c55e70a9053114 259 SMART SM00382 32 219 8.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_21390 2c036d8682e765f214c55e70a9053114 259 SUPERFAMILY SSF52540 3 224 3.12E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21390 2c036d8682e765f214c55e70a9053114 259 Gene3D G3DSA:3.40.50.300 1 248 1.1E-65 T 14-10-2018 C2I25_21390 2c036d8682e765f214c55e70a9053114 259 Pfam PF00005 ABC transporter 23 171 2.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21390 2c036d8682e765f214c55e70a9053114 259 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_19145 1b1fa043bc6a5df194f7fb2a47e3e905 261 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 231 5.2E-28 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_19145 1b1fa043bc6a5df194f7fb2a47e3e905 261 Gene3D G3DSA:3.30.1240.10 82 188 2.1E-54 T 14-10-2018 C2I25_19145 1b1fa043bc6a5df194f7fb2a47e3e905 261 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 252 1.5E-48 T 14-10-2018 C2I25_19145 1b1fa043bc6a5df194f7fb2a47e3e905 261 Gene3D G3DSA:3.40.50.1000 3 252 2.1E-54 T 14-10-2018 IPR023214 HAD superfamily C2I25_19145 1b1fa043bc6a5df194f7fb2a47e3e905 261 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 252 1.2E-47 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_19145 1b1fa043bc6a5df194f7fb2a47e3e905 261 SUPERFAMILY SSF56784 1 252 4.49E-56 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_03905 17c479950f88a363a71912ac0e3cc2b6 349 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 3.9E-120 T 14-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 C2I25_03905 17c479950f88a363a71912ac0e3cc2b6 349 Pfam PF01070 FMN-dependent dehydrogenase 167 323 6.9E-18 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 C2I25_03905 17c479950f88a363a71912ac0e3cc2b6 349 SMART SM01240 21 336 0.0079 T 14-10-2018 C2I25_03905 17c479950f88a363a71912ac0e3cc2b6 349 SUPERFAMILY SSF51395 22 348 1.41E-84 T 14-10-2018 C2I25_03905 17c479950f88a363a71912ac0e3cc2b6 349 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 38.427 T 14-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 C2I25_03905 17c479950f88a363a71912ac0e3cc2b6 349 PIRSF PIRSF003314 2 340 1.0E-122 T 14-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 C2I25_03905 17c479950f88a363a71912ac0e3cc2b6 349 Gene3D G3DSA:3.20.20.70 3 349 6.7E-127 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_26710 cf4ad78cbba63bb0193edfb0470b0569 303 Pfam PF07261 Replication initiation and membrane attachment 166 232 5.3E-17 T 14-10-2018 IPR006343 DnaD domain C2I25_26710 cf4ad78cbba63bb0193edfb0470b0569 303 SUPERFAMILY SSF158499 165 227 1.19E-17 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_26710 cf4ad78cbba63bb0193edfb0470b0569 303 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 165 232 4.2E-23 T 14-10-2018 IPR006343 DnaD domain C2I25_26710 cf4ad78cbba63bb0193edfb0470b0569 303 Gene3D G3DSA:1.10.10.630 162 233 6.5E-22 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_23365 e5c490b210594af6691d32f31f45cc07 299 SUPERFAMILY SSF53474 6 299 3.35E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_23365 e5c490b210594af6691d32f31f45cc07 299 Gene3D G3DSA:3.40.50.1820 11 299 4.6E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_23365 e5c490b210594af6691d32f31f45cc07 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 9.0E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_23365 e5c490b210594af6691d32f31f45cc07 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 9.0E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_23365 e5c490b210594af6691d32f31f45cc07 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 9.0E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_23365 e5c490b210594af6691d32f31f45cc07 299 Pfam PF00561 alpha/beta hydrolase fold 31 285 1.2E-28 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_16775 ebb8954efa6292421d889ddee0f8f6d0 275 PIRSF PIRSF019271 1 275 1.3E-108 T 14-10-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 C2I25_16775 ebb8954efa6292421d889ddee0f8f6d0 275 SUPERFAMILY SSF56784 58 250 7.6E-45 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_16775 ebb8954efa6292421d889ddee0f8f6d0 275 Gene3D G3DSA:3.40.50.1000 24 275 1.1E-95 T 14-10-2018 IPR023214 HAD superfamily C2I25_16775 ebb8954efa6292421d889ddee0f8f6d0 275 TIGRFAM TIGR01533 lipo_e_P4: 5'-nucleotidase, lipoprotein e(P4) family 9 272 1.8E-93 T 14-10-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 C2I25_16775 ebb8954efa6292421d889ddee0f8f6d0 275 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 33 245 1.2E-48 T 14-10-2018 IPR005519 Acid phosphatase, class B-like C2I25_14245 6ebca376c8ad317d51f8ec92243f3942 184 SUPERFAMILY SSF53254 1 175 2.06E-30 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_14245 6ebca376c8ad317d51f8ec92243f3942 184 SMART SM00855 3 143 2.2E-4 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_14245 6ebca376c8ad317d51f8ec92243f3942 184 Gene3D G3DSA:3.40.50.1240 1 177 1.1E-25 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_14245 6ebca376c8ad317d51f8ec92243f3942 184 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 173 1.3E-21 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_04880 abc6c08a168c973780184910e0f4ce8e 283 Gene3D G3DSA:1.20.1080.10 2 264 1.9E-83 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I25_04880 abc6c08a168c973780184910e0f4ce8e 283 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 76 85 - T 14-10-2018 IPR024002 Formate/nitrite transporter, conserved site C2I25_04880 abc6c08a168c973780184910e0f4ce8e 283 Pfam PF01226 Formate/nitrite transporter 9 251 9.2E-68 T 14-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 C2I25_04880 abc6c08a168c973780184910e0f4ce8e 283 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 160 170 - T 14-10-2018 IPR024002 Formate/nitrite transporter, conserved site C2I25_16450 4de5c6eacd94e12aa681e97e79e56a1f 163 SUPERFAMILY SSF101386 1 163 8.94E-49 T 14-10-2018 C2I25_16450 4de5c6eacd94e12aa681e97e79e56a1f 163 Pfam PF08761 dUTPase 2 163 9.7E-53 T 14-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 C2I25_16450 4de5c6eacd94e12aa681e97e79e56a1f 163 PIRSF PIRSF030140 1 163 1.5E-59 T 14-10-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 C2I25_16450 4de5c6eacd94e12aa681e97e79e56a1f 163 Gene3D G3DSA:1.10.4010.10 1 163 2.4E-15 T 14-10-2018 C2I25_00430 76096b6312e6b214d2da152efdbd025d 90 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 4.2E-27 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_00430 76096b6312e6b214d2da152efdbd025d 90 Pfam PF06013 Proteins of 100 residues with WXG 3 88 1.1E-22 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_00430 76096b6312e6b214d2da152efdbd025d 90 SUPERFAMILY SSF158414 5 79 1.11E-22 T 14-10-2018 IPR029013 HP0062-like domain superfamily C2I25_00430 76096b6312e6b214d2da152efdbd025d 90 Gene3D G3DSA:1.10.287.850 1 90 7.0E-35 T 14-10-2018 C2I25_10540 bf88b1020fc2e432d1fc323597b0d4fb 546 Gene3D G3DSA:3.10.105.10 295 517 6.0E-176 T 14-10-2018 C2I25_10540 bf88b1020fc2e432d1fc323597b0d4fb 546 Gene3D G3DSA:3.40.190.10 55 534 6.0E-176 T 14-10-2018 C2I25_10540 bf88b1020fc2e432d1fc323597b0d4fb 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 465 6.5E-77 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_10540 bf88b1020fc2e432d1fc323597b0d4fb 546 Gene3D G3DSA:3.90.76.10 74 195 6.0E-176 T 14-10-2018 C2I25_10540 bf88b1020fc2e432d1fc323597b0d4fb 546 SUPERFAMILY SSF53850 35 541 4.71E-122 T 14-10-2018 C2I25_10540 bf88b1020fc2e432d1fc323597b0d4fb 546 PIRSF PIRSF002741 1 546 1.1E-105 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_03585 31805541007cf9e86547a98eab331146 379 SUPERFAMILY SSF53335 144 361 3.47E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_03585 31805541007cf9e86547a98eab331146 379 Pfam PF02926 THUMP domain 20 154 1.7E-16 T 14-10-2018 IPR004114 THUMP domain GO:0003723 C2I25_03585 31805541007cf9e86547a98eab331146 379 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 14-10-2018 IPR000241 Putative RNA methylase domain C2I25_03585 31805541007cf9e86547a98eab331146 379 Gene3D G3DSA:3.30.2130.30 8 246 9.1E-122 T 14-10-2018 C2I25_03585 31805541007cf9e86547a98eab331146 379 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 C2I25_03585 31805541007cf9e86547a98eab331146 379 Gene3D G3DSA:3.40.50.150 161 365 9.1E-122 T 14-10-2018 C2I25_03585 31805541007cf9e86547a98eab331146 379 Pfam PF01170 Putative RNA methylase family UPF0020 163 367 4.4E-65 T 14-10-2018 IPR000241 Putative RNA methylase domain C2I25_03585 31805541007cf9e86547a98eab331146 379 SMART SM00981 57 155 2.5E-8 T 14-10-2018 IPR004114 THUMP domain GO:0003723 C2I25_16630 30fa38a39b3ec0380dc1bc3af9628cd9 230 SUPERFAMILY SSF52172 2 128 4.98E-40 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_16630 30fa38a39b3ec0380dc1bc3af9628cd9 230 SMART SM00448 3 113 1.8E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_16630 30fa38a39b3ec0380dc1bc3af9628cd9 230 Gene3D G3DSA:3.40.50.2300 1 130 1.2E-37 T 14-10-2018 C2I25_16630 30fa38a39b3ec0380dc1bc3af9628cd9 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 3.3E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_16630 30fa38a39b3ec0380dc1bc3af9628cd9 230 Gene3D G3DSA:1.10.10.10 131 230 5.4E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_16630 30fa38a39b3ec0380dc1bc3af9628cd9 230 SUPERFAMILY SSF46894 130 228 3.4E-32 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_16630 30fa38a39b3ec0380dc1bc3af9628cd9 230 Pfam PF00072 Response regulator receiver domain 5 113 2.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_16630 30fa38a39b3ec0380dc1bc3af9628cd9 230 SMART SM00862 151 227 2.9E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_01715 b6d295491164a0f91c4ce6694363bda3 602 Gene3D G3DSA:1.10.510.40 407 542 2.8E-12 T 14-10-2018 C2I25_01715 b6d295491164a0f91c4ce6694363bda3 602 Pfam PF04183 IucA / IucC family 153 387 1.8E-54 T 14-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 C2I25_01715 b6d295491164a0f91c4ce6694363bda3 602 Pfam PF06276 Ferric iron reductase FhuF-like transporter 419 578 4.2E-39 T 14-10-2018 IPR022770 Ferric iron reductase FhuF domain C2I25_11095 d77b76ae6beb08b01c89fcd32dd50ed6 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.293 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I25_11095 d77b76ae6beb08b01c89fcd32dd50ed6 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 8.7E-74 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I25_11095 d77b76ae6beb08b01c89fcd32dd50ed6 158 SUPERFAMILY SSF69765 1 157 2.09E-67 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I25_11095 d77b76ae6beb08b01c89fcd32dd50ed6 158 Pfam PF02542 YgbB family 2 156 2.3E-67 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I25_11095 d77b76ae6beb08b01c89fcd32dd50ed6 158 Gene3D G3DSA:3.30.1330.50 1 158 8.9E-70 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I25_11095 d77b76ae6beb08b01c89fcd32dd50ed6 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I25_24320 2520ab60b096d24bd2e69b159b2de8ad 308 Gene3D G3DSA:3.90.1200.10 100 292 2.1E-22 T 14-10-2018 C2I25_24320 2520ab60b096d24bd2e69b159b2de8ad 308 SUPERFAMILY SSF56112 21 259 2.04E-34 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_24320 2520ab60b096d24bd2e69b159b2de8ad 308 Pfam PF01636 Phosphotransferase enzyme family 20 249 2.1E-29 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_20120 0494002f48349340fc6d35369137eeca 356 Gene3D G3DSA:3.90.230.10 127 354 2.4E-85 T 14-10-2018 C2I25_20120 0494002f48349340fc6d35369137eeca 356 SUPERFAMILY SSF55920 86 348 6.28E-83 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I25_20120 0494002f48349340fc6d35369137eeca 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 284 296 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site C2I25_20120 0494002f48349340fc6d35369137eeca 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 306 318 6.9E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_20120 0494002f48349340fc6d35369137eeca 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 208 224 6.9E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_20120 0494002f48349340fc6d35369137eeca 356 SUPERFAMILY SSF53092 1 127 7.32E-26 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I25_20120 0494002f48349340fc6d35369137eeca 356 Pfam PF00557 Metallopeptidase family M24 136 338 1.6E-68 T 14-10-2018 IPR000994 Peptidase M24 C2I25_20120 0494002f48349340fc6d35369137eeca 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 128 6.6E-24 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 C2I25_20120 0494002f48349340fc6d35369137eeca 356 Gene3D G3DSA:3.40.350.10 1 126 4.8E-34 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I25_13200 4a15b0e5f12e166c1a8fc1ad15516ea5 234 Pfam PF04794 YdjC-like protein 3 228 7.5E-61 T 14-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like C2I25_13200 4a15b0e5f12e166c1a8fc1ad15516ea5 234 SUPERFAMILY SSF88713 1 229 1.58E-72 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_13200 4a15b0e5f12e166c1a8fc1ad15516ea5 234 Gene3D G3DSA:3.20.20.370 2 234 2.7E-79 T 14-10-2018 C2I25_13200 4a15b0e5f12e166c1a8fc1ad15516ea5 234 Hamap MF_01246 Chitooligosaccharide deacetylase [chbG]. 2 234 40.827 T 14-10-2018 IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria GO:0000272|GO:0016811 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 SUPERFAMILY SSF158472 211 259 2.09E-10 T 14-10-2018 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 SUPERFAMILY SSF55785 257 374 2.62E-11 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 SMART SM00304 210 262 2.9E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 SMART SM00387 494 606 4.0E-42 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 267 382 1.6E-6 T 14-10-2018 IPR000014 PAS domain C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 SUPERFAMILY SSF47384 368 448 1.2E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Pfam PF00672 HAMP domain 211 259 1.8E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:3.30.450.20 32 188 2.1E-38 T 14-10-2018 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 495 604 4.6E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Pfam PF00512 His Kinase A (phospho-acceptor) domain 383 448 6.9E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 SUPERFAMILY SSF55874 438 608 2.75E-49 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Pfam PF00989 PAS fold 271 319 6.6E-8 T 14-10-2018 IPR013767 PAS fold GO:0006355 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:1.10.287.130 374 453 3.8E-29 T 14-10-2018 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 584 1.1E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 545 1.1E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 603 1.1E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 559 1.1E-20 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:3.30.565.10 454 612 2.4E-49 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:3.30.450.20 281 373 5.4E-22 T 14-10-2018 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:1.10.287.130 208 280 1.7E-11 T 14-10-2018 C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 SMART SM00091 269 335 6.2E-7 T 14-10-2018 IPR000014 PAS domain C2I25_11785 9d151ff160d221b4c39e36116d0b1946 613 SMART SM00388 382 449 6.2E-20 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_05260 2a9d7c4ffcb6c1b6c0ff24923d2b836b 172 Pfam PF13563 2'-5' RNA ligase superfamily 13 153 1.6E-24 T 14-10-2018 C2I25_05260 2a9d7c4ffcb6c1b6c0ff24923d2b836b 172 Gene3D G3DSA:3.90.1140.10 2 171 3.5E-44 T 14-10-2018 C2I25_05260 2a9d7c4ffcb6c1b6c0ff24923d2b836b 172 Hamap MF_01444 Putative phosphoesterase . 1 168 39.296 T 14-10-2018 IPR022932 Putative phosphoesterase YjcG C2I25_05260 2a9d7c4ffcb6c1b6c0ff24923d2b836b 172 SUPERFAMILY SSF55144 1 170 2.62E-33 T 14-10-2018 IPR009097 Cyclic phosphodiesterase C2I25_19190 92bffebc60d83926fcb8727deebd1887 300 SMART SM00849 56 249 3.4E-5 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_19190 92bffebc60d83926fcb8727deebd1887 300 Pfam PF00753 Metallo-beta-lactamase superfamily 54 247 1.2E-10 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_19190 92bffebc60d83926fcb8727deebd1887 300 Gene3D G3DSA:3.60.15.10 44 291 1.5E-69 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_19190 92bffebc60d83926fcb8727deebd1887 300 SUPERFAMILY SSF56281 46 289 1.06E-47 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_19480 0338210822d0234082cf05835e1a635d 513 Gene3D G3DSA:1.20.1720.10 17 224 1.5E-53 T 14-10-2018 C2I25_19480 0338210822d0234082cf05835e1a635d 513 SUPERFAMILY SSF103473 5 498 1.31E-74 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_19480 0338210822d0234082cf05835e1a635d 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 490 3.5E-79 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_19480 0338210822d0234082cf05835e1a635d 513 Pfam PF07690 Major Facilitator Superfamily 20 411 3.2E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_01005 fd869408bfe0ed4db83be63ac3e04960 389 Gene3D G3DSA:1.20.1250.20 2 178 1.3E-37 T 14-10-2018 C2I25_01005 fd869408bfe0ed4db83be63ac3e04960 389 SUPERFAMILY SSF103473 16 379 7.46E-60 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_01005 fd869408bfe0ed4db83be63ac3e04960 389 Gene3D G3DSA:1.20.1250.20 186 384 4.0E-51 T 14-10-2018 C2I25_01005 fd869408bfe0ed4db83be63ac3e04960 389 Pfam PF07690 Major Facilitator Superfamily 16 340 2.9E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_18895 dba8d92694b118bc38de459a8b7e60f5 214 Gene3D G3DSA:2.40.30.20 1 88 2.1E-32 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_18895 dba8d92694b118bc38de459a8b7e60f5 214 SUPERFAMILY SSF63380 1 89 4.59E-27 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I25_18895 dba8d92694b118bc38de459a8b7e60f5 214 Gene3D G3DSA:2.40.30.20 101 202 6.5E-32 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_18895 dba8d92694b118bc38de459a8b7e60f5 214 Pfam PF00677 Lumazine binding domain 3 86 1.3E-24 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18895 dba8d92694b118bc38de459a8b7e60f5 214 Pfam PF00677 Lumazine binding domain 99 183 7.9E-21 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18895 dba8d92694b118bc38de459a8b7e60f5 214 PIRSF PIRSF000498 1 208 2.2E-76 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_18895 dba8d92694b118bc38de459a8b7e60f5 214 SUPERFAMILY SSF63380 92 195 2.81E-31 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I25_18895 dba8d92694b118bc38de459a8b7e60f5 214 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 1.4E-78 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I25_16090 e828d268e118bae6e6ba4f313a1a9296 212 Pfam PF11167 Protein of unknown function (DUF2953) 121 173 1.5E-19 T 14-10-2018 IPR021338 Protein of unknown function DUF2953 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 Gene3D G3DSA:2.70.210.12 1 157 1.5E-59 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 SUPERFAMILY SSF82051 1 157 2.35E-54 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 Gene3D G3DSA:2.40.240.60 356 428 2.9E-18 T 14-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 426 2.2E-26 T 14-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 SUPERFAMILY SSF52540 160 334 2.7E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.4E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.4E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.4E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.4E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 PIRSF PIRSF002401 1 375 1.0E-141 T 14-10-2018 IPR035101 GTP-binding protein, Obg-type C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 SUPERFAMILY SSF102741 357 428 1.96E-23 T 14-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 48.065 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 4.0E-14 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.4E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 6.2E-25 T 14-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 1.0E-142 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 Gene3D G3DSA:3.40.50.300 158 340 1.6E-61 T 14-10-2018 C2I25_17075 226e0bc15a4fe6e89b7008c11524ada2 428 Pfam PF01018 GTP1/OBG 3 157 3.0E-59 T 14-10-2018 IPR006169 GTP1/OBG domain C2I25_21035 b97ed95957dfc40fdd36d416bbeee28a 218 Gene3D G3DSA:3.40.50.1390 1 156 5.4E-27 T 14-10-2018 C2I25_21035 b97ed95957dfc40fdd36d416bbeee28a 218 SUPERFAMILY SSF53041 1 149 1.7E-25 T 14-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 C2I25_21035 b97ed95957dfc40fdd36d416bbeee28a 218 Pfam PF00239 Resolvase, N terminal domain 3 147 2.1E-26 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I25_21035 b97ed95957dfc40fdd36d416bbeee28a 218 SMART SM00857 3 149 2.3E-34 T 14-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I25_24880 2d5d88ac69f3fc941c0f1b095d20165c 318 SUPERFAMILY SSF53686 5 302 7.33E-58 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_24880 2d5d88ac69f3fc941c0f1b095d20165c 318 Gene3D G3DSA:3.40.50.1100 13 301 6.3E-67 T 14-10-2018 C2I25_24880 2d5d88ac69f3fc941c0f1b095d20165c 318 Gene3D G3DSA:3.40.50.1100 46 145 6.3E-67 T 14-10-2018 C2I25_24880 2d5d88ac69f3fc941c0f1b095d20165c 318 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 298 2.2E-40 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_24880 2d5d88ac69f3fc941c0f1b095d20165c 318 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 36 49 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 C2I25_24880 2d5d88ac69f3fc941c0f1b095d20165c 318 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 C2I25_01310 20cda6ff26a2d5955399493299f30327 246 Gene3D G3DSA:3.30.1380.10 37 246 3.7E-76 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_01310 20cda6ff26a2d5955399493299f30327 246 SUPERFAMILY SSF55166 91 236 9.94E-37 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_01310 20cda6ff26a2d5955399493299f30327 246 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 99 227 1.8E-45 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 C2I25_10255 d95592253238e9a153de8361b9d6b4da 116 Gene3D G3DSA:2.30.30.110 1 116 6.7E-53 T 14-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor C2I25_10255 d95592253238e9a153de8361b9d6b4da 116 PIRSF PIRSF033490 1 113 4.9E-39 T 14-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 C2I25_10255 d95592253238e9a153de8361b9d6b4da 116 SUPERFAMILY SSF50118 2 113 7.68E-41 T 14-10-2018 C2I25_10255 d95592253238e9a153de8361b9d6b4da 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 1.8E-32 T 14-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 C2I25_05275 f198921e4588736d035ddd02a656f98a 155 Pfam PF10612 Spore coat protein Z 4 152 2.4E-41 T 14-10-2018 IPR019593 Spore coat protein Z/Y C2I25_28250 fe4d97be4034558cfdbc358e96a3432f 302 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 16 295 2.7E-130 T 14-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 C2I25_28250 fe4d97be4034558cfdbc358e96a3432f 302 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 256 1.5E-53 T 14-10-2018 C2I25_28250 fe4d97be4034558cfdbc358e96a3432f 302 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 296 48.521 T 14-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 C2I25_28250 fe4d97be4034558cfdbc358e96a3432f 302 SUPERFAMILY SSF51621 9 294 4.49E-99 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I25_28250 fe4d97be4034558cfdbc358e96a3432f 302 Gene3D G3DSA:3.20.20.60 1 302 3.3E-115 T 14-10-2018 C2I25_28250 fe4d97be4034558cfdbc358e96a3432f 302 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 C2I25_24290 1819302f17670b488689a26ff5ad0f22 256 Gene3D G3DSA:1.25.40.290 126 245 4.4E-31 T 14-10-2018 C2I25_24290 1819302f17670b488689a26ff5ad0f22 256 SUPERFAMILY SSF48371 10 246 1.68E-44 T 14-10-2018 IPR016024 Armadillo-type fold C2I25_24290 1819302f17670b488689a26ff5ad0f22 256 Pfam PF08713 DNA alkylation repair enzyme 125 239 2.7E-10 T 14-10-2018 IPR014825 DNA alkylation repair enzyme C2I25_22755 496e05d14ea4b5e30bb2742516e84783 137 Pfam PF02082 Transcriptional regulator 2 79 1.0E-20 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type C2I25_22755 496e05d14ea4b5e30bb2742516e84783 137 SUPERFAMILY SSF46785 2 131 5.79E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22755 496e05d14ea4b5e30bb2742516e84783 137 Gene3D G3DSA:1.10.10.10 1 137 2.6E-40 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_11290 39997b6ef67d0e5dc44844afc51349c9 808 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 605 790 4.1E-36 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_11290 39997b6ef67d0e5dc44844afc51349c9 808 Gene3D G3DSA:3.60.40.10 572 808 6.8E-52 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_11290 39997b6ef67d0e5dc44844afc51349c9 808 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 28 790 9.1E-255 T 14-10-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_11290 39997b6ef67d0e5dc44844afc51349c9 808 SMART SM00331 578 790 4.7E-51 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_11290 39997b6ef67d0e5dc44844afc51349c9 808 SMART SM00332 587 788 6.5E-4 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_11290 39997b6ef67d0e5dc44844afc51349c9 808 SUPERFAMILY SSF81606 579 791 2.35E-21 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_06055 40b6f446edeeb9e9fac354ec146f24dd 705 Pfam PF00912 Transglycosylase 51 225 8.2E-67 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_06055 40b6f446edeeb9e9fac354ec146f24dd 705 Gene3D G3DSA:3.90.1310.20 46 499 1.4E-184 T 14-10-2018 C2I25_06055 40b6f446edeeb9e9fac354ec146f24dd 705 Gene3D G3DSA:3.40.710.10 291 604 1.4E-184 T 14-10-2018 C2I25_06055 40b6f446edeeb9e9fac354ec146f24dd 705 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 62 593 1.8E-171 T 14-10-2018 C2I25_06055 40b6f446edeeb9e9fac354ec146f24dd 705 Gene3D G3DSA:1.10.3810.10 61 249 1.4E-184 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_06055 40b6f446edeeb9e9fac354ec146f24dd 705 SUPERFAMILY SSF56601 207 609 2.54E-96 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_06055 40b6f446edeeb9e9fac354ec146f24dd 705 SUPERFAMILY SSF53955 40 244 2.17E-74 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily C2I25_06055 40b6f446edeeb9e9fac354ec146f24dd 705 Pfam PF00905 Penicillin binding protein transpeptidase domain 317 589 5.4E-36 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_22620 b0767554792337d4171c69d2b33c5561 86 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 17 83 2.5E-10 T 14-10-2018 IPR008792 Coenzyme PQQ synthesis D C2I25_28265 bc5a356843fbbf673c148cf3e53ea6db 96 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 92 9.8E-7 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I25_28265 bc5a356843fbbf673c148cf3e53ea6db 96 PIRSF PIRSF034852 1 96 1.5E-35 T 14-10-2018 IPR008326 Uncharacterised conserved protein UCP034852 C2I25_28265 bc5a356843fbbf673c148cf3e53ea6db 96 SUPERFAMILY SSF89360 1 94 6.67E-9 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I25_09700 761fcac6977379dd453f3d32a2144352 458 SUPERFAMILY SSF50249 3 65 1.43E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_09700 761fcac6977379dd453f3d32a2144352 458 Gene3D G3DSA:3.40.1350.30 134 289 6.3E-127 T 14-10-2018 C2I25_09700 761fcac6977379dd453f3d32a2144352 458 Pfam PF02475 Met-10+ like-protein 211 360 4.2E-9 T 14-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 C2I25_09700 761fcac6977379dd453f3d32a2144352 458 Gene3D G3DSA:2.40.50.140 3 85 4.6E-21 T 14-10-2018 C2I25_09700 761fcac6977379dd453f3d32a2144352 458 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 383 456 8.1E-13 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 C2I25_09700 761fcac6977379dd453f3d32a2144352 458 Pfam PF01938 TRAM domain 12 64 2.8E-11 T 14-10-2018 IPR002792 TRAM domain C2I25_09700 761fcac6977379dd453f3d32a2144352 458 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 440 450 - T 14-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site C2I25_09700 761fcac6977379dd453f3d32a2144352 458 Gene3D G3DSA:3.40.50.150 87 452 6.3E-127 T 14-10-2018 C2I25_09700 761fcac6977379dd453f3d32a2144352 458 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 22 450 4.0E-188 T 14-10-2018 C2I25_09700 761fcac6977379dd453f3d32a2144352 458 SUPERFAMILY SSF53335 74 455 2.39E-89 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_09700 761fcac6977379dd453f3d32a2144352 458 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 388 419 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site C2I25_15870 afb4cc2f53e1ede1f0cec69e8fc3470a 340 PIRSF PIRSF012509 1 340 5.0E-94 T 14-10-2018 IPR011426 CamS sex pheromone cAM373 C2I25_15870 afb4cc2f53e1ede1f0cec69e8fc3470a 340 Gene3D G3DSA:3.30.300.190 224 340 7.3E-41 T 14-10-2018 C2I25_15870 afb4cc2f53e1ede1f0cec69e8fc3470a 340 Gene3D G3DSA:3.10.570.10 54 223 1.3E-56 T 14-10-2018 C2I25_15870 afb4cc2f53e1ede1f0cec69e8fc3470a 340 Pfam PF07537 CamS sex pheromone cAM373 precursor 120 333 9.0E-47 T 14-10-2018 IPR011426 CamS sex pheromone cAM373 C2I25_15870 afb4cc2f53e1ede1f0cec69e8fc3470a 340 Pfam PF07537 CamS sex pheromone cAM373 precursor 70 116 7.6E-6 T 14-10-2018 IPR011426 CamS sex pheromone cAM373 C2I25_26760 610b0838f2cc09182718b382f3fccea8 111 TIGRFAM TIGR03601 B_an_ocin: bacteriocin, heterocycloanthracin/sonorensin family 3 93 1.1E-40 T 14-10-2018 IPR019890 Bacteriocin, heterocycloanthracin/sonorensin family C2I25_20400 f511d7cfcd8064d924c5643222a4466c 263 Pfam PF01148 Cytidylyltransferase family 2 262 7.2E-71 T 14-10-2018 C2I25_20400 f511d7cfcd8064d924c5643222a4466c 263 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 221 247 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 C2I25_23110 eefe3e0e2f0ce01efb644a227e621dd0 279 Pfam PF10978 Protein of unknown function (DUF2785) 80 253 4.9E-49 T 14-10-2018 IPR021247 Protein of unknown function DUF2785 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 Pfam PF00012 Hsp70 protein 76 573 8.4E-217 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 SUPERFAMILY SSF100920 354 510 2.88E-60 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 Gene3D G3DSA:1.20.1270.10 477 577 9.8E-24 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 Gene3D G3DSA:3.30.420.40 158 337 2.1E-151 T 14-10-2018 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 Gene3D G3DSA:3.30.420.40 5 346 2.1E-151 T 14-10-2018 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 3.6E-281 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 607 36.817 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 Gene3D G3DSA:3.90.640.10 198 279 2.1E-151 T 14-10-2018 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 Gene3D G3DSA:2.60.34.10 348 476 3.4E-57 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 53 61 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 358 377 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 439 455 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 112 132 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 PRINTS PR00301 70kDa heat shock protein signature 335 355 5.3E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 SUPERFAMILY SSF53067 161 352 2.22E-66 T 14-10-2018 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 SUPERFAMILY SSF53067 1 157 6.31E-58 T 14-10-2018 C2I25_17705 de3f74b1340c41e292d774533407f66e 611 SUPERFAMILY SSF100934 477 575 5.1E-11 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 C2I25_01280 16c983beda9ed8c69980013d8aec1212 384 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 176 376 1.4E-64 T 14-10-2018 IPR010897 Sporulation stage II, protein P C2I25_01280 16c983beda9ed8c69980013d8aec1212 384 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 101 371 3.5E-69 T 14-10-2018 IPR010897 Sporulation stage II, protein P C2I25_01280 16c983beda9ed8c69980013d8aec1212 384 SUPERFAMILY SSF53187 209 376 1.38E-6 T 14-10-2018 C2I25_16940 d9c6f262b83493c96f53cf07a982e6ca 138 Gene3D G3DSA:3.30.300.20 45 138 2.8E-35 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_16940 d9c6f262b83493c96f53cf07a982e6ca 138 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 3.2E-56 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 C2I25_16940 d9c6f262b83493c96f53cf07a982e6ca 138 Gene3D G3DSA:2.20.25.10 1 44 3.0E-19 T 14-10-2018 C2I25_16940 d9c6f262b83493c96f53cf07a982e6ca 138 Pfam PF02566 OsmC-like protein 40 135 4.8E-18 T 14-10-2018 IPR003718 OsmC/Ohr family C2I25_16940 d9c6f262b83493c96f53cf07a982e6ca 138 SUPERFAMILY SSF82784 1 137 1.44E-42 T 14-10-2018 IPR036102 OsmC/Ohr superfamily C2I25_13660 0690530806be201afee300507acc1f88 185 Pfam PF00857 Isochorismatase family 4 148 6.7E-40 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_13660 0690530806be201afee300507acc1f88 185 Gene3D G3DSA:3.40.50.850 1 185 5.6E-48 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_13660 0690530806be201afee300507acc1f88 185 SUPERFAMILY SSF52499 2 181 4.06E-49 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_17015 0af65f59cab7268581594fc017611dec 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 335 4.8E-161 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_17015 0af65f59cab7268581594fc017611dec 339 Gene3D G3DSA:3.30.420.40 153 316 3.5E-131 T 14-10-2018 C2I25_17015 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 46 64 3.1E-60 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_17015 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 66 89 3.1E-60 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_17015 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 186 206 3.1E-60 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_17015 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 299 325 3.1E-60 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_17015 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 131 150 3.1E-60 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_17015 0af65f59cab7268581594fc017611dec 339 Pfam PF06723 MreB/Mbl protein 9 334 6.5E-152 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_17015 0af65f59cab7268581594fc017611dec 339 SUPERFAMILY SSF53067 8 146 3.11E-39 T 14-10-2018 C2I25_17015 0af65f59cab7268581594fc017611dec 339 SUPERFAMILY SSF53067 149 332 6.79E-51 T 14-10-2018 C2I25_17015 0af65f59cab7268581594fc017611dec 339 Gene3D G3DSA:3.90.640.10 185 258 3.5E-131 T 14-10-2018 C2I25_17015 0af65f59cab7268581594fc017611dec 339 Gene3D G3DSA:3.30.420.40 11 326 3.5E-131 T 14-10-2018 C2I25_23940 bc117f4f1814b6eac12daea17af8c276 120 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 112 8.6E-40 T 14-10-2018 IPR018745 Domain of unknown function DUF2294 C2I25_17090 3413efb4b2b6acb6685cacbb3366ac72 258 SMART SM00382 33 221 1.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_17090 3413efb4b2b6acb6685cacbb3366ac72 258 Pfam PF00005 ABC transporter 24 172 2.5E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_17090 3413efb4b2b6acb6685cacbb3366ac72 258 SUPERFAMILY SSF52540 3 225 2.5E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17090 3413efb4b2b6acb6685cacbb3366ac72 258 Gene3D G3DSA:3.40.50.300 1 252 4.0E-66 T 14-10-2018 C2I25_18240 6d3aaa6ae64c9c2a04d9d6bc45c51a63 104 Gene3D G3DSA:1.10.3730.20 1 104 5.7E-30 T 14-10-2018 C2I25_18240 6d3aaa6ae64c9c2a04d9d6bc45c51a63 104 Pfam PF00893 Small Multidrug Resistance protein 1 92 3.4E-27 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I25_18240 6d3aaa6ae64c9c2a04d9d6bc45c51a63 104 SUPERFAMILY SSF103481 5 102 1.44E-18 T 14-10-2018 C2I25_15435 7ffc11e3da49eb1225c61e9eccd611e4 200 Gene3D G3DSA:3.90.550.10 7 200 1.8E-49 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_15435 7ffc11e3da49eb1225c61e9eccd611e4 200 SUPERFAMILY SSF53448 1 193 3.38E-30 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_15435 7ffc11e3da49eb1225c61e9eccd611e4 200 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 2 193 23.337 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 C2I25_15435 7ffc11e3da49eb1225c61e9eccd611e4 200 Pfam PF12804 MobA-like NTP transferase domain 6 155 2.0E-30 T 14-10-2018 IPR025877 MobA-like NTP transferase C2I25_08345 b2edcff90c9a11c2077056cd908915fd 465 Pfam PF13520 Amino acid permease 7 429 7.8E-51 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_08345 b2edcff90c9a11c2077056cd908915fd 465 PIRSF PIRSF006060 1 463 9.2E-56 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_08345 b2edcff90c9a11c2077056cd908915fd 465 Gene3D G3DSA:1.20.1740.10 1 465 6.0E-63 T 14-10-2018 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 Gene3D G3DSA:3.30.470.20 1 234 7.5E-98 T 14-10-2018 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 SUPERFAMILY SSF56059 1 238 4.52E-86 T 14-10-2018 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 Pfam PF00549 CoA-ligase 262 381 1.3E-26 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.951 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 Gene3D G3DSA:3.30.1490.20 21 104 7.5E-98 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 SUPERFAMILY SSF52210 240 385 5.49E-55 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 PIRSF PIRSF001554 1 386 1.3E-156 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 2.6E-166 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 Gene3D G3DSA:3.40.50.261 240 386 2.9E-57 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I25_20330 92c8c5ff1d6f08e8b1fa4482d558dcb7 386 Pfam PF08442 ATP-grasp domain 2 202 1.3E-83 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_09025 f64987fcc5aee8ef397e53dd4fb75f10 376 Pfam PF01979 Amidohydrolase family 52 368 3.0E-19 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I25_09025 f64987fcc5aee8ef397e53dd4fb75f10 376 SUPERFAMILY SSF51338 3 371 5.81E-21 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_09025 f64987fcc5aee8ef397e53dd4fb75f10 376 SUPERFAMILY SSF51556 54 336 9.08E-43 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_09025 f64987fcc5aee8ef397e53dd4fb75f10 376 Gene3D G3DSA:2.30.40.10 5 366 6.5E-104 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_09025 f64987fcc5aee8ef397e53dd4fb75f10 376 Gene3D G3DSA:3.20.20.140 55 332 6.5E-104 T 14-10-2018 C2I25_14000 6547b29d7bbc189163e483873d495975 390 Pfam PF07690 Major Facilitator Superfamily 8 340 2.9E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_14000 6547b29d7bbc189163e483873d495975 390 Gene3D G3DSA:1.20.1250.20 3 198 4.6E-26 T 14-10-2018 C2I25_14000 6547b29d7bbc189163e483873d495975 390 Gene3D G3DSA:1.20.1250.20 199 382 9.6E-24 T 14-10-2018 C2I25_14000 6547b29d7bbc189163e483873d495975 390 SUPERFAMILY SSF103473 4 377 3.66E-61 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_10960 e4f8ed7e0459f9ad9bdf9874e879add0 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 20.572 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 C2I25_10960 e4f8ed7e0459f9ad9bdf9874e879add0 96 SUPERFAMILY SSF54189 1 91 1.73E-30 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10960 e4f8ed7e0459f9ad9bdf9874e879add0 96 Pfam PF00276 Ribosomal protein L23 6 88 3.9E-31 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 C2I25_10960 e4f8ed7e0459f9ad9bdf9874e879add0 96 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 14-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10960 e4f8ed7e0459f9ad9bdf9874e879add0 96 Gene3D G3DSA:3.30.70.330 1 96 1.6E-31 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily C2I25_22175 67e98a2fe69489c07978bed8c4ec0bbd 175 Pfam PF04229 GrpB protein 5 173 4.2E-45 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase C2I25_22175 67e98a2fe69489c07978bed8c4ec0bbd 175 SUPERFAMILY SSF81301 7 174 3.27E-43 T 14-10-2018 C2I25_22175 67e98a2fe69489c07978bed8c4ec0bbd 175 Gene3D G3DSA:3.30.460.10 2 175 2.5E-49 T 14-10-2018 C2I25_14225 8e2f7b2e63731cf46f88b45cf81062b0 243 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 17 231 2.2E-81 T 14-10-2018 IPR014197 Sporulation protein YunB C2I25_14225 8e2f7b2e63731cf46f88b45cf81062b0 243 PIRSF PIRSF021383 3 236 3.9E-66 T 14-10-2018 IPR014197 Sporulation protein YunB C2I25_14225 8e2f7b2e63731cf46f88b45cf81062b0 243 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 138 227 7.8E-30 T 14-10-2018 IPR014197 Sporulation protein YunB C2I25_03515 f2683cf7e41ce68f6cc028dd9c472800 277 SUPERFAMILY SSF52821 2 150 2.75E-41 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_03515 f2683cf7e41ce68f6cc028dd9c472800 277 Gene3D G3DSA:3.40.250.10 145 277 8.0E-33 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_03515 f2683cf7e41ce68f6cc028dd9c472800 277 SMART SM00450 153 270 8.1E-17 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_03515 f2683cf7e41ce68f6cc028dd9c472800 277 SMART SM00450 3 129 1.2E-21 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_03515 f2683cf7e41ce68f6cc028dd9c472800 277 Pfam PF00581 Rhodanese-like domain 155 265 1.6E-14 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_03515 f2683cf7e41ce68f6cc028dd9c472800 277 Pfam PF00581 Rhodanese-like domain 4 125 8.1E-22 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_03515 f2683cf7e41ce68f6cc028dd9c472800 277 Gene3D G3DSA:3.40.250.10 1 144 5.1E-47 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_03515 f2683cf7e41ce68f6cc028dd9c472800 277 SUPERFAMILY SSF52821 147 273 7.99E-33 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_08020 3f5f75607170e77a841dba71f1c01a6a 430 PIRSF PIRSF005353 1 430 3.4E-146 T 14-10-2018 IPR026033 Purine permease PbuG-like C2I25_08020 3f5f75607170e77a841dba71f1c01a6a 430 Pfam PF00860 Permease family 13 393 6.9E-45 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I25_07285 9d2d4c0f823360aeb0100f698cca2504 270 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 255 29.277 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type C2I25_07285 9d2d4c0f823360aeb0100f698cca2504 270 SUPERFAMILY SSF100939 2 260 1.53E-39 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily C2I25_07285 9d2d4c0f823360aeb0100f698cca2504 270 PIRSF PIRSF006493 1 270 9.7E-78 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type C2I25_07285 9d2d4c0f823360aeb0100f698cca2504 270 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 258 1.1E-74 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type C2I25_07285 9d2d4c0f823360aeb0100f698cca2504 270 Gene3D G3DSA:2.40.290.10 2 181 1.3E-16 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily C2I25_07285 9d2d4c0f823360aeb0100f698cca2504 270 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 193 8.2E-32 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 C2I25_07285 9d2d4c0f823360aeb0100f698cca2504 270 SMART SM00559 53 182 2.8E-22 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 Gene3D G3DSA:3.30.930.10 103 432 6.4E-103 T 14-10-2018 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 Pfam PF01336 OB-fold nucleic acid binding domain 21 93 7.2E-10 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 SUPERFAMILY SSF50249 12 101 9.26E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 16 432 1.9E-136 T 14-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 Pfam PF00152 tRNA synthetases class II (D, K and N) 114 425 1.4E-83 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 387 401 3.4E-22 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 199 212 3.4E-22 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 3.4E-22 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 347 363 3.4E-22 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 SUPERFAMILY SSF55681 90 430 1.09E-86 T 14-10-2018 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 5 432 40.229 T 14-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I25_00455 d9ffe14412af4cdfa04e8385cdc921f8 432 Gene3D G3DSA:2.40.50.140 6 99 3.3E-20 T 14-10-2018 C2I25_13415 964704253da8b465307b33d5a04a5f5f 270 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 265 1.1E-85 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I25_13415 964704253da8b465307b33d5a04a5f5f 270 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 256 1.7E-78 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I25_13415 964704253da8b465307b33d5a04a5f5f 270 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 261 17.709 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I25_13415 964704253da8b465307b33d5a04a5f5f 270 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 137 149 - T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I25_13425 0aed9db63bfa0d509135309e187c8c72 170 SUPERFAMILY SSF51161 11 158 2.77E-32 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_13425 0aed9db63bfa0d509135309e187c8c72 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 107 140 3.2E-9 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_13425 0aed9db63bfa0d509135309e187c8c72 170 Gene3D G3DSA:2.160.10.10 13 168 6.5E-28 T 14-10-2018 C2I25_13210 42fc61788cbc6c7102e436fc7a50974a 137 Pfam PF07452 CHRD domain 5 132 3.9E-22 T 14-10-2018 IPR010895 CHRD C2I25_13210 42fc61788cbc6c7102e436fc7a50974a 137 SMART SM00754 3 134 1.2E-39 T 14-10-2018 IPR010895 CHRD C2I25_16545 d079cb9e5de1cd43e8c177abbcc88efb 179 Pfam PF02674 Colicin V production protein 2 159 5.4E-34 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 239 266 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 Gene3D G3DSA:3.30.470.20 94 289 7.4E-77 T 14-10-2018 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 SUPERFAMILY SSF56059 94 292 2.73E-49 T 14-10-2018 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 Pfam PF01820 D-ala D-ala ligase N-terminus 2 84 5.8E-22 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 Gene3D G3DSA:3.30.1490.20 109 175 7.4E-77 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 295 4.7E-89 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 61 72 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 Gene3D G3DSA:3.40.50.20 1 82 2.4E-32 T 14-10-2018 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 296 35.595 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 PIRSF PIRSF039102 1 48 2.6E-11 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 PIRSF PIRSF039102 41 303 1.7E-101 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 SMART SM01209 93 263 0.0011 T 14-10-2018 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 Pfam PF07478 D-ala D-ala ligase C-terminus 104 293 1.4E-52 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_26780 2f85b53d9257c713083a271fc6e01c84 304 SUPERFAMILY SSF52440 1 94 2.59E-28 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_17395 9b3dc97b91da5d5ba5f7e46181393cba 71 Pfam PF10750 Protein of unknown function (DUF2536) 1 68 5.2E-37 T 14-10-2018 IPR019686 Protein of unknown function DUF2536 C2I25_22305 ad82238b6c942aacce9425438bdfabc2 236 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 15 223 4.0E-32 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_22305 ad82238b6c942aacce9425438bdfabc2 236 PIRSF PIRSF000709 7 113 3.0E-6 T 14-10-2018 C2I25_22305 ad82238b6c942aacce9425438bdfabc2 236 SMART SM00855 14 188 4.9E-16 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_22305 ad82238b6c942aacce9425438bdfabc2 236 Gene3D G3DSA:3.40.50.1240 2 236 9.3E-65 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_22305 ad82238b6c942aacce9425438bdfabc2 236 SUPERFAMILY SSF53254 14 232 9.56E-45 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_25155 32a84c04c8870e4211273f7f85eba537 223 Pfam PF14172 Domain of unknown function (DUF4309) 86 212 1.8E-43 T 14-10-2018 IPR025453 Protein of unknown function DUF4309 C2I25_16020 da32cb7dcfda7318d147bc77f1ef607a 391 Gene3D G3DSA:3.90.1150.10 258 391 3.8E-47 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_16020 da32cb7dcfda7318d147bc77f1ef607a 391 PIRSF PIRSF001434 1 387 9.6E-144 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_16020 da32cb7dcfda7318d147bc77f1ef607a 391 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 4 385 3.1E-167 T 14-10-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 C2I25_16020 da32cb7dcfda7318d147bc77f1ef607a 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 384 6.0E-141 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_16020 da32cb7dcfda7318d147bc77f1ef607a 391 SUPERFAMILY SSF53383 26 386 6.19E-118 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_16020 da32cb7dcfda7318d147bc77f1ef607a 391 Gene3D G3DSA:3.40.640.10 1 257 1.1E-93 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_20015 dd3c1380208e56c9945d1f3258ae974f 168 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.7E-17 T 14-10-2018 IPR019933 DivIVA domain C2I25_20015 dd3c1380208e56c9945d1f3258ae974f 168 Pfam PF05103 DivIVA protein 3 133 6.8E-52 T 14-10-2018 IPR007793 DivIVA family C2I25_28035 0e5d8dbefe1a97d086f97fb5d78de0e2 216 SMART SM00860 32 173 3.4E-8 T 14-10-2018 IPR018958 Knr4/Smi1-like domain C2I25_28035 0e5d8dbefe1a97d086f97fb5d78de0e2 216 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 34 172 3.2E-14 T 14-10-2018 IPR018958 Knr4/Smi1-like domain C2I25_28035 0e5d8dbefe1a97d086f97fb5d78de0e2 216 SUPERFAMILY SSF160631 7 187 3.79E-20 T 14-10-2018 C2I25_28035 0e5d8dbefe1a97d086f97fb5d78de0e2 216 Gene3D G3DSA:3.40.1580.10 16 178 1.6E-17 T 14-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I25_11695 fb9c28c136dff49d54367b606b816cf6 273 Gene3D G3DSA:3.90.1530.30 28 90 1.1E-27 T 14-10-2018 C2I25_11695 fb9c28c136dff49d54367b606b816cf6 273 SMART SM00470 15 104 4.7E-35 T 14-10-2018 IPR003115 ParB/Sulfiredoxin C2I25_11695 fb9c28c136dff49d54367b606b816cf6 273 SUPERFAMILY SSF110849 16 106 1.62E-27 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily C2I25_11695 fb9c28c136dff49d54367b606b816cf6 273 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 12 189 1.2E-61 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 C2I25_11695 fb9c28c136dff49d54367b606b816cf6 273 Pfam PF01381 Helix-turn-helix 121 154 1.2E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_11695 fb9c28c136dff49d54367b606b816cf6 273 Pfam PF02195 ParB-like nuclease domain 16 103 8.5E-28 T 14-10-2018 IPR003115 ParB/Sulfiredoxin C2I25_11695 fb9c28c136dff49d54367b606b816cf6 273 SUPERFAMILY SSF109709 96 207 2.28E-36 T 14-10-2018 C2I25_11695 fb9c28c136dff49d54367b606b816cf6 273 Gene3D G3DSA:1.10.10.2830 91 205 2.8E-38 T 14-10-2018 C2I25_19690 e238803fb19c017596aa5d48bd058e10 208 Gene3D G3DSA:3.30.930.20 1 208 1.1E-86 T 14-10-2018 C2I25_19690 e238803fb19c017596aa5d48bd058e10 208 PIRSF PIRSF021332 1 208 6.5E-95 T 14-10-2018 IPR009403 Protein of unknown function UPF0637 C2I25_19690 e238803fb19c017596aa5d48bd058e10 208 Hamap MF_01851 UPF0637 protein . 5 205 39.443 T 14-10-2018 IPR009403 Protein of unknown function UPF0637 C2I25_19690 e238803fb19c017596aa5d48bd058e10 208 Pfam PF06335 Protein of unknown function (DUF1054) 6 203 1.0E-85 T 14-10-2018 IPR009403 Protein of unknown function UPF0637 C2I25_19690 e238803fb19c017596aa5d48bd058e10 208 SUPERFAMILY SSF142913 3 206 5.23E-83 T 14-10-2018 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 266 29.619 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 Gene3D G3DSA:3.40.50.720 5 263 2.1E-73 T 14-10-2018 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 128 9.1E-32 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 Gene3D G3DSA:3.30.360.10 130 235 2.1E-73 T 14-10-2018 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 131 264 1.9E-32 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 PIRSF PIRSF000161 2 266 1.5E-67 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 SUPERFAMILY SSF55347 129 237 4.36E-38 T 14-10-2018 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 266 6.0E-85 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 SUPERFAMILY SSF51735 4 155 6.68E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_03735 3b7b39e922c3c7576cbf06e9aae94d4e 266 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00690 Adhesin family signature 65 78 4.5E-11 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00690 Adhesin family signature 78 95 4.5E-11 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00690 Adhesin family signature 34 52 4.5E-11 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00690 Adhesin family signature 201 222 4.5E-11 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 SUPERFAMILY SSF53807 16 314 2.65E-86 T 14-10-2018 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 Gene3D G3DSA:3.40.50.1980 24 203 7.6E-61 T 14-10-2018 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 Gene3D G3DSA:3.40.50.1980 204 316 3.4E-39 T 14-10-2018 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 Pfam PF01297 Zinc-uptake complex component A periplasmic 37 314 5.1E-79 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00691 Adhesin B signature 145 164 1.6E-11 T 14-10-2018 IPR006129 Adhesin B GO:0007155 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00691 Adhesin B signature 294 312 1.6E-11 T 14-10-2018 IPR006129 Adhesin B GO:0007155 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00691 Adhesin B signature 34 55 1.6E-11 T 14-10-2018 IPR006129 Adhesin B GO:0007155 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00691 Adhesin B signature 59 77 1.6E-11 T 14-10-2018 IPR006129 Adhesin B GO:0007155 C2I25_01495 fa58cd1f36db21ed6407a7cb858d5928 316 PRINTS PR00691 Adhesin B signature 201 218 1.6E-11 T 14-10-2018 IPR006129 Adhesin B GO:0007155 C2I25_14960 2a0e696baf9a32d8a193270461ed23bd 441 PIRSF PIRSF002746 1 441 4.1E-145 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_14960 2a0e696baf9a32d8a193270461ed23bd 441 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 5 441 5.2E-138 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_14960 2a0e696baf9a32d8a193270461ed23bd 441 Pfam PF02447 GntP family permease 5 439 1.4E-145 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_06805 207a3705285f283918ae00a21f6af21b 225 PIRSF PIRSF006171 1 224 2.7E-78 T 14-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 C2I25_06805 207a3705285f283918ae00a21f6af21b 225 Pfam PF00072 Response regulator receiver domain 4 115 8.1E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_06805 207a3705285f283918ae00a21f6af21b 225 SUPERFAMILY SSF52172 1 140 2.13E-27 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_06805 207a3705285f283918ae00a21f6af21b 225 SMART SM00448 2 115 1.5E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_06805 207a3705285f283918ae00a21f6af21b 225 Gene3D G3DSA:3.40.50.12740 2 205 5.9E-28 T 14-10-2018 C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 SUPERFAMILY SSF54211 80 159 3.79E-26 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.7E-31 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 7.8E-73 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 Gene3D G3DSA:3.30.230.10 74 166 2.3E-37 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 SUPERFAMILY SSF54768 9 76 1.36E-25 T 14-10-2018 C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.021 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 4.2E-33 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 C2I25_10885 3149f812515dc415e17f9e6c3d36ddcc 166 Gene3D G3DSA:3.30.160.20 1 73 6.4E-36 T 14-10-2018 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 ProSitePatterns PS00517 Ribonuclease III family signature. 58 66 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 Pfam PF00035 Double-stranded RNA binding motif 175 241 2.0E-17 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 22 241 6.8E-82 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 SUPERFAMILY SSF69065 15 177 2.27E-54 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 Gene3D G3DSA:3.30.160.20 173 244 5.4E-23 T 14-10-2018 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 Hamap MF_00104 Ribonuclease 3 [rnc]. 22 238 32.024 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 Pfam PF14622 Ribonuclease-III-like 32 160 3.8E-38 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 SMART SM00535 34 169 2.6E-60 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 Gene3D G3DSA:1.10.1520.10 15 168 2.3E-50 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 SMART SM00358 175 242 2.1E-22 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain C2I25_20265 fb68139ee259d26026f4e20bbacc3075 245 SUPERFAMILY SSF54768 131 241 1.51E-24 T 14-10-2018 C2I25_02090 c52cb9b590583e22150230f99659e868 239 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 113 218 2.4E-19 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_02090 c52cb9b590583e22150230f99659e868 239 Gene3D G3DSA:3.90.470.20 27 229 2.2E-56 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_02090 c52cb9b590583e22150230f99659e868 239 Gene3D G3DSA:3.90.470.20 114 219 2.2E-56 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_02090 c52cb9b590583e22150230f99659e868 239 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 113 207 1.8E-13 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I25_02090 c52cb9b590583e22150230f99659e868 239 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 118 171 1.0E-4 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I25_02090 c52cb9b590583e22150230f99659e868 239 SUPERFAMILY SSF56214 113 223 6.8E-27 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_02090 c52cb9b590583e22150230f99659e868 239 SUPERFAMILY SSF56214 11 105 3.01E-19 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I25_24225 7b0a32213d07c781a5fc10ed189c3804 329 SMART SM00797 24 317 1.9E-135 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I25_24225 7b0a32213d07c781a5fc10ed189c3804 329 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 300 1.0E-86 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I25_24225 7b0a32213d07c781a5fc10ed189c3804 329 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 324 2.3E-92 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I25_24225 7b0a32213d07c781a5fc10ed189c3804 329 SUPERFAMILY SSF50891 193 307 3.22E-12 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_24225 7b0a32213d07c781a5fc10ed189c3804 329 Gene3D G3DSA:2.40.100.10 190 326 1.0E-49 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I25_06555 8fa59786536be27edfdf13ca7f14f7e6 211 Pfam PF04892 VanZ like family 43 161 5.7E-24 T 14-10-2018 IPR006976 VanZ-like C2I25_14975 dcaa328e9bd68941dba3afff02b74c1b 63 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 19 38 6.3E-10 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_14975 dcaa328e9bd68941dba3afff02b74c1b 63 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 19 40 1.1E-9 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_02115 b69ef6d16dd94476e45aa8786951d7f1 457 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 20 427 3.0E-157 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_02115 b69ef6d16dd94476e45aa8786951d7f1 457 Pfam PF05525 Branched-chain amino acid transport protein 16 438 1.8E-162 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_21020 f47e6544ef2dbbda888fbc5a37efe4da 180 Pfam PF08006 Protein of unknown function (DUF1700) 1 179 2.9E-71 T 14-10-2018 IPR012963 Protein of unknown function DUF1700 C2I25_14020 97974a3112806163b93067b865b5697c 100 SUPERFAMILY SSF89957 1 100 1.3E-32 T 14-10-2018 IPR029756 MTH1187/YkoF-like C2I25_14020 97974a3112806163b93067b865b5697c 100 Gene3D G3DSA:3.30.70.930 1 100 9.8E-39 T 14-10-2018 IPR029756 MTH1187/YkoF-like C2I25_14020 97974a3112806163b93067b865b5697c 100 Pfam PF01910 Thiamine-binding protein 4 97 6.2E-35 T 14-10-2018 IPR002767 Thiamine-binding protein C2I25_14020 97974a3112806163b93067b865b5697c 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 100 1.2E-33 T 14-10-2018 IPR002767 Thiamine-binding protein C2I25_20640 f2ac545156860177fd47824facf5b817 307 SUPERFAMILY SSF51556 1 304 6.29E-75 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_20640 f2ac545156860177fd47824facf5b817 307 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 305 1.2E-102 T 14-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 C2I25_20640 f2ac545156860177fd47824facf5b817 307 Gene3D G3DSA:3.20.20.140 1 306 5.3E-108 T 14-10-2018 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 Gene3D G3DSA:3.90.1170.30 336 423 5.3E-34 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 305 2.8E-48 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 SUPERFAMILY SSF47648 1 69 1.44E-24 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 SUPERFAMILY SSF52418 69 329 1.44E-92 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.6E-24 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 7.2E-27 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 Gene3D G3DSA:3.40.1030.10 69 335 4.8E-118 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 14-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 SMART SM00941 345 418 2.3E-30 T 14-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 Gene3D G3DSA:1.20.970.10 1 67 3.3E-31 T 14-10-2018 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 SUPERFAMILY SSF54680 331 431 1.44E-29 T 14-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 PIRSF PIRSF000478 1 432 9.9E-171 T 14-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_02205 b5059e26bd2bbd393faecdcb154c1bb2 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 5.5E-186 T 14-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_22495 8ff6b95be24cabb97d26ca81af1e6d61 96 Pfam PF12650 Domain of unknown function (DUF3784) 10 93 3.7E-12 T 14-10-2018 IPR017259 Uncharacterised conserved protein UCP037672 C2I25_27205 c9188b6a151101927a71c1cbcfc082f0 179 Pfam PF04542 Sigma-70 region 2 20 83 1.0E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_27205 c9188b6a151101927a71c1cbcfc082f0 179 SUPERFAMILY SSF88946 12 91 9.02E-19 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_27205 c9188b6a151101927a71c1cbcfc082f0 179 Gene3D G3DSA:1.10.1740.10 3 82 2.1E-20 T 14-10-2018 C2I25_27205 c9188b6a151101927a71c1cbcfc082f0 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 169 2.7E-31 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_27205 c9188b6a151101927a71c1cbcfc082f0 179 Pfam PF08281 Sigma-70, region 4 117 166 5.1E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_27205 c9188b6a151101927a71c1cbcfc082f0 179 SUPERFAMILY SSF88659 104 171 6.54E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_27205 c9188b6a151101927a71c1cbcfc082f0 179 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 41 72 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_27205 c9188b6a151101927a71c1cbcfc082f0 179 Gene3D G3DSA:1.10.10.10 95 173 1.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20575 d1f5f81b8de89366d45baee28b019903 424 SUPERFAMILY SSF63411 243 411 7.5E-33 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I25_20575 d1f5f81b8de89366d45baee28b019903 424 Pfam PF05193 Peptidase M16 inactive domain 184 356 5.4E-27 T 14-10-2018 IPR007863 Peptidase M16, C-terminal C2I25_20575 d1f5f81b8de89366d45baee28b019903 424 SUPERFAMILY SSF63411 12 232 1.75E-25 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I25_20575 d1f5f81b8de89366d45baee28b019903 424 Gene3D G3DSA:3.30.830.10 239 424 7.1E-44 T 14-10-2018 C2I25_20575 d1f5f81b8de89366d45baee28b019903 424 Gene3D G3DSA:3.30.830.10 7 236 1.3E-62 T 14-10-2018 C2I25_04870 4e1915400949b2b9b6064331b96829a6 439 Pfam PF02386 Cation transport protein 17 423 7.8E-60 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 C2I25_04870 4e1915400949b2b9b6064331b96829a6 439 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 28 410 1.7E-110 T 14-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 C2I25_24110 d71454c22c44dcf117407a5643649add 70 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 43 57 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_24110 d71454c22c44dcf117407a5643649add 70 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 64 5.7E-23 T 14-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I25_24110 d71454c22c44dcf117407a5643649add 70 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_24110 d71454c22c44dcf117407a5643649add 70 Gene3D G3DSA:1.10.8.910 10 70 1.5E-31 T 14-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I25_09965 fd0ca15149cdba7a698a45f78853e508 306 SUPERFAMILY SSF103481 186 286 6.67E-14 T 14-10-2018 C2I25_09965 fd0ca15149cdba7a698a45f78853e508 306 SUPERFAMILY SSF103481 38 140 3.53E-14 T 14-10-2018 C2I25_09965 fd0ca15149cdba7a698a45f78853e508 306 Pfam PF00892 EamA-like transporter family 2 136 6.5E-23 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_09965 fd0ca15149cdba7a698a45f78853e508 306 Pfam PF00892 EamA-like transporter family 149 284 7.5E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_12480 9f6738bd0437b4efb931d8d72408dcec 174 Gene3D G3DSA:3.40.50.10490 1 174 1.8E-58 T 14-10-2018 C2I25_12480 9f6738bd0437b4efb931d8d72408dcec 174 SUPERFAMILY SSF53697 22 169 2.26E-5 T 14-10-2018 C2I25_12480 9f6738bd0437b4efb931d8d72408dcec 174 Pfam PF10740 Domain of unknown function (DUF2529) 1 171 1.3E-66 T 14-10-2018 IPR019676 Domain of unknown function (DUF2529) C2I25_24070 900a4319d53c32442dc0cf0c28c946ab 443 PIRSF PIRSF036794 23 443 2.5E-160 T 14-10-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type C2I25_24070 900a4319d53c32442dc0cf0c28c946ab 443 SUPERFAMILY SSF159501 41 441 7.59E-117 T 14-10-2018 C2I25_24070 900a4319d53c32442dc0cf0c28c946ab 443 Gene3D G3DSA:3.40.1660.10 45 436 9.4E-153 T 14-10-2018 C2I25_24070 900a4319d53c32442dc0cf0c28c946ab 443 Gene3D G3DSA:1.20.1440.30 176 302 9.4E-153 T 14-10-2018 C2I25_24070 900a4319d53c32442dc0cf0c28c946ab 443 Gene3D G3DSA:3.30.1870.10 104 175 9.4E-153 T 14-10-2018 C2I25_24070 900a4319d53c32442dc0cf0c28c946ab 443 Pfam PF05139 Erythromycin esterase 102 435 8.8E-69 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 C2I25_05760 70c9f4a7583e135c586a8fb2df0a906a 425 Pfam PF00463 Isocitrate lyase family 11 250 7.5E-57 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 C2I25_05760 70c9f4a7583e135c586a8fb2df0a906a 425 Gene3D G3DSA:3.20.20.60 4 406 1.4E-172 T 14-10-2018 C2I25_05760 70c9f4a7583e135c586a8fb2df0a906a 425 PIRSF PIRSF001362 1 425 5.8E-241 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 C2I25_05760 70c9f4a7583e135c586a8fb2df0a906a 425 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 6 248 2.3E-108 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 C2I25_05760 70c9f4a7583e135c586a8fb2df0a906a 425 SUPERFAMILY SSF51621 5 423 1.93E-156 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I25_05760 70c9f4a7583e135c586a8fb2df0a906a 425 ProSitePatterns PS00161 Isocitrate lyase signature. 184 189 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 C2I25_12255 38556ba1b7e40eb13baac9e2d5148070 351 Gene3D G3DSA:1.10.3470.10 23 349 1.8E-89 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_12255 38556ba1b7e40eb13baac9e2d5148070 351 Pfam PF01032 FecCD transport family 35 344 2.1E-88 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_12255 38556ba1b7e40eb13baac9e2d5148070 351 SUPERFAMILY SSF81345 22 344 1.83E-83 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_05235 cbea454c53e6213820e2e811a9a2a9c9 492 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site C2I25_05235 cbea454c53e6213820e2e811a9a2a9c9 492 Gene3D G3DSA:1.20.1730.10 22 491 3.2E-105 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I25_05235 cbea454c53e6213820e2e811a9a2a9c9 492 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 433 6.3E-101 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_05235 cbea454c53e6213820e2e811a9a2a9c9 492 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 487 1.6E-221 T 14-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 C2I25_05235 cbea454c53e6213820e2e811a9a2a9c9 492 Pfam PF00474 Sodium:solute symporter family 35 433 7.3E-108 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_02645 3bde71f2f13a541812d503ede49994ca 312 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_02645 3bde71f2f13a541812d503ede49994ca 312 SUPERFAMILY SSF52540 3 222 7.77E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02645 3bde71f2f13a541812d503ede49994ca 312 Pfam PF00005 ABC transporter 19 162 4.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_02645 3bde71f2f13a541812d503ede49994ca 312 SMART SM00382 28 210 9.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_02645 3bde71f2f13a541812d503ede49994ca 312 Pfam PF13732 Domain of unknown function (DUF4162) 217 304 5.9E-7 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 C2I25_02645 3bde71f2f13a541812d503ede49994ca 312 Gene3D G3DSA:3.40.50.300 1 231 1.1E-71 T 14-10-2018 C2I25_12075 bb0ec3acbac5093452ec28c42f24ac2e 246 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 64 231 1.3E-61 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 C2I25_12075 bb0ec3acbac5093452ec28c42f24ac2e 246 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 62 236 1.2E-55 T 14-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 C2I25_12075 bb0ec3acbac5093452ec28c42f24ac2e 246 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 4 246 64.036 T 14-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 C2I25_28580 b770e8e9652baf2a5ca2e9e0d341862b 503 SUPERFAMILY SSF53850 233 501 2.58E-75 T 14-10-2018 C2I25_28580 b770e8e9652baf2a5ca2e9e0d341862b 503 Gene3D G3DSA:3.40.190.10 244 502 1.4E-97 T 14-10-2018 C2I25_28580 b770e8e9652baf2a5ca2e9e0d341862b 503 SUPERFAMILY SSF161098 15 198 6.02E-42 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_28580 b770e8e9652baf2a5ca2e9e0d341862b 503 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 233 498 2.4E-69 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 C2I25_28580 b770e8e9652baf2a5ca2e9e0d341862b 503 Gene3D G3DSA:1.10.3720.10 12 206 8.2E-38 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_28580 b770e8e9652baf2a5ca2e9e0d341862b 503 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 202 1.2E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_28580 b770e8e9652baf2a5ca2e9e0d341862b 503 Gene3D G3DSA:3.40.190.120 337 440 1.4E-97 T 14-10-2018 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 327 3.4E-65 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 4 330 45.45 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 SUPERFAMILY SSF51735 5 184 1.29E-73 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 Gene3D G3DSA:1.10.3730.40 184 336 4.2E-69 T 14-10-2018 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 Gene3D G3DSA:3.40.50.720 3 183 2.1E-79 T 14-10-2018 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 PIRSF PIRSF000116 2 206 6.4E-40 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 PIRSF PIRSF000116 203 334 6.1E-13 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 SUPERFAMILY SSF48179 185 330 2.61E-69 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 2.2E-78 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_04410 2a2823fca8e0139edbb68b1e0f327d82 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 17 328 9.4E-142 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I25_10635 7657eee2b1f2e167e48d74f48fd1afbf 222 SUPERFAMILY SSF161098 13 206 4.71E-43 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10635 7657eee2b1f2e167e48d74f48fd1afbf 222 Gene3D G3DSA:1.10.3720.10 9 222 1.2E-48 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10635 7657eee2b1f2e167e48d74f48fd1afbf 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 205 1.0E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 PIRSF PIRSF004803 2 557 1.3E-240 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 366 394 - T 14-10-2018 IPR001587 Ribonuclease J, conserved site C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 SUPERFAMILY SSF56281 9 426 3.2E-97 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 Gene3D G3DSA:3.40.50.10710 207 357 3.6E-183 T 14-10-2018 C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 Pfam PF00753 Metallo-beta-lactamase superfamily 20 166 2.8E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 SMART SM00849 20 223 2.1E-28 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 Gene3D G3DSA:3.10.20.580 451 557 4.7E-36 T 14-10-2018 C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 555 5.0E-203 T 14-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 Hamap MF_01491 Ribonuclease J [rnj]. 3 557 46.673 T 14-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 365 407 4.3E-11 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain C2I25_24095 b14c0d6a1f40918d9fa095aa55bd71ef 557 Gene3D G3DSA:3.60.15.10 11 444 3.6E-183 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_17180 26fa109eb50e46d9d5cde96bd57834ee 350 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 2.2E-152 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 C2I25_17180 26fa109eb50e46d9d5cde96bd57834ee 350 Gene3D G3DSA:3.40.1780.10 14 341 7.9E-138 T 14-10-2018 C2I25_17180 26fa109eb50e46d9d5cde96bd57834ee 350 Pfam PF02547 Queuosine biosynthesis protein 5 341 3.5E-144 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 C2I25_17180 26fa109eb50e46d9d5cde96bd57834ee 350 SUPERFAMILY SSF111337 1 341 2.09E-141 T 14-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 C2I25_17180 26fa109eb50e46d9d5cde96bd57834ee 350 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.592 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 C2I25_17180 26fa109eb50e46d9d5cde96bd57834ee 350 Gene3D G3DSA:2.40.10.240 64 162 7.9E-138 T 14-10-2018 C2I25_12295 9b3e5adc894e5b7ae4cc06ba1f1a0ffe 683 Gene3D G3DSA:3.40.710.10 256 663 1.1E-116 T 14-10-2018 C2I25_12295 9b3e5adc894e5b7ae4cc06ba1f1a0ffe 683 Pfam PF00905 Penicillin binding protein transpeptidase domain 325 597 2.2E-33 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_12295 9b3e5adc894e5b7ae4cc06ba1f1a0ffe 683 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 70 603 7.3E-182 T 14-10-2018 C2I25_12295 9b3e5adc894e5b7ae4cc06ba1f1a0ffe 683 SUPERFAMILY SSF56601 216 657 2.0E-120 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_12295 9b3e5adc894e5b7ae4cc06ba1f1a0ffe 683 Pfam PF00912 Transglycosylase 61 234 2.1E-61 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_12295 9b3e5adc894e5b7ae4cc06ba1f1a0ffe 683 SUPERFAMILY SSF53955 47 260 6.19E-74 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily C2I25_12295 9b3e5adc894e5b7ae4cc06ba1f1a0ffe 683 Gene3D G3DSA:1.10.3810.10 52 250 8.4E-74 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_07510 dc0dba872e805873424427eb09872d54 505 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 25 481 6.8E-148 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_07510 dc0dba872e805873424427eb09872d54 505 PIRSF PIRSF005690 6 496 4.8E-134 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 SUPERFAMILY SSF46785 4 60 6.38E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.5E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.5E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 SMART SM00420 6 58 1.9E-12 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 Pfam PF00455 DeoR C terminal sensor domain 82 231 1.5E-31 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 SMART SM01134 74 232 9.7E-40 T 14-10-2018 C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 8.5E-15 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 Gene3D G3DSA:1.10.10.10 1 92 1.7E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25745 e051eeb0aab498bb051f8a711fdd5631 261 SUPERFAMILY SSF100950 82 231 2.93E-21 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_22610 9ea8f8024c1b7d684b82c71233aecad6 178 Gene3D G3DSA:3.40.50.360 1 177 4.8E-54 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_22610 9ea8f8024c1b7d684b82c71233aecad6 178 SUPERFAMILY SSF52218 1 172 1.36E-44 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_22610 9ea8f8024c1b7d684b82c71233aecad6 178 Pfam PF02525 Flavodoxin-like fold 2 168 4.5E-43 T 14-10-2018 IPR003680 Flavodoxin-like fold C2I25_07495 d6357e1ef1771cc806bc4e926989b64f 470 Pfam PF04293 SpoVR like protein 7 408 1.4E-162 T 14-10-2018 IPR007390 Sporulation stage V, protein R C2I25_26610 98f3aa0f51ff0e25ddf0076702784cab 166 Pfam PF13384 Homeodomain-like domain 11 44 1.4E-6 T 14-10-2018 C2I25_26610 98f3aa0f51ff0e25ddf0076702784cab 166 Pfam PF05119 Phage terminase, small subunit 76 156 1.5E-6 T 14-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family C2I25_11530 a8b80fbcb8f0ea7b5a8d82cd398bb5f0 166 Pfam PF14437 MafB19-like deaminase 5 151 5.1E-43 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 C2I25_11530 a8b80fbcb8f0ea7b5a8d82cd398bb5f0 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I25_11530 a8b80fbcb8f0ea7b5a8d82cd398bb5f0 166 SUPERFAMILY SSF53927 3 155 2.17E-56 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_11530 a8b80fbcb8f0ea7b5a8d82cd398bb5f0 166 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 151 47.012 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 C2I25_11530 a8b80fbcb8f0ea7b5a8d82cd398bb5f0 166 Gene3D G3DSA:3.40.140.10 1 166 2.5E-63 T 14-10-2018 C2I25_27585 569a49aa28d4cb1e0a10ef3d968ae1ca 169 Pfam PF08761 dUTPase 2 169 1.9E-44 T 14-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 C2I25_27585 569a49aa28d4cb1e0a10ef3d968ae1ca 169 Gene3D G3DSA:1.10.4010.10 1 169 3.1E-15 T 14-10-2018 C2I25_27585 569a49aa28d4cb1e0a10ef3d968ae1ca 169 SUPERFAMILY SSF101386 2 169 7.85E-43 T 14-10-2018 C2I25_27585 569a49aa28d4cb1e0a10ef3d968ae1ca 169 PIRSF PIRSF030140 1 169 5.4E-52 T 14-10-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 C2I25_11395 e4108df975925ba716565dd6586ba65f 86 Pfam PF06257 Biofilm formation stimulator VEG 4 74 1.1E-29 T 14-10-2018 IPR009366 Protein Veg GO:0006355 C2I25_11395 e4108df975925ba716565dd6586ba65f 86 Gene3D G3DSA:2.30.30.100 1 78 1.4E-25 T 14-10-2018 C2I25_11395 e4108df975925ba716565dd6586ba65f 86 PIRSF PIRSF037257 1 85 1.7E-35 T 14-10-2018 IPR009366 Protein Veg GO:0006355 C2I25_26640 3b92fa2d3a37a63f3a77acf732a6c0bc 389 Pfam PF00144 Beta-lactamase 63 372 4.4E-66 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_26640 3b92fa2d3a37a63f3a77acf732a6c0bc 389 SUPERFAMILY SSF56601 53 380 5.2E-80 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_26640 3b92fa2d3a37a63f3a77acf732a6c0bc 389 Gene3D G3DSA:3.40.710.10 47 389 5.7E-138 T 14-10-2018 C2I25_15210 0c5abd1e44d2f3f973f9857e7d2bdc4e 449 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 433 7.0E-175 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I25_15210 0c5abd1e44d2f3f973f9857e7d2bdc4e 449 PIRSF PIRSF006446 1 448 6.0E-173 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I25_26415 c55a8a9a36b24f967f654725c420423d 392 Gene3D G3DSA:3.40.50.2000 4 387 1.1E-100 T 14-10-2018 C2I25_26415 c55a8a9a36b24f967f654725c420423d 392 SUPERFAMILY SSF53756 3 390 5.02E-74 T 14-10-2018 C2I25_26415 c55a8a9a36b24f967f654725c420423d 392 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 391 4.9E-94 T 14-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 C2I25_26415 c55a8a9a36b24f967f654725c420423d 392 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 224 369 1.4E-14 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 C2I25_26415 c55a8a9a36b24f967f654725c420423d 392 Gene3D G3DSA:3.40.50.2000 209 375 1.1E-100 T 14-10-2018 C2I25_03410 b7517779620ef0ae8cba8010059ea5f1 186 SUPERFAMILY SSF52499 2 175 8.63E-33 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_03410 b7517779620ef0ae8cba8010059ea5f1 186 Gene3D G3DSA:3.40.50.850 1 164 2.7E-31 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_03410 b7517779620ef0ae8cba8010059ea5f1 186 Pfam PF00857 Isochorismatase family 4 140 2.4E-22 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_17855 d1fa1c54004c776f91b24d470ad66d87 436 Pfam PF00270 DEAD/DEAH box helicase 28 196 2.0E-42 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_17855 d1fa1c54004c776f91b24d470ad66d87 436 Gene3D G3DSA:3.40.50.300 220 436 7.5E-46 T 14-10-2018 C2I25_17855 d1fa1c54004c776f91b24d470ad66d87 436 SMART SM00490 260 341 4.7E-29 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_17855 d1fa1c54004c776f91b24d470ad66d87 436 SUPERFAMILY SSF52540 73 360 1.8E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17855 d1fa1c54004c776f91b24d470ad66d87 436 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 436 50.665 T 14-10-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 C2I25_17855 d1fa1c54004c776f91b24d470ad66d87 436 Gene3D G3DSA:3.40.50.300 2 218 4.4E-68 T 14-10-2018 C2I25_17855 d1fa1c54004c776f91b24d470ad66d87 436 SMART SM00487 23 224 1.3E-53 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_17855 d1fa1c54004c776f91b24d470ad66d87 436 Pfam PF00271 Helicase conserved C-terminal domain 233 341 6.2E-25 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_01185 e059e6ae6abd0310a59847185c1cde84 121 SUPERFAMILY SSF51182 16 99 2.72E-8 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_01185 e059e6ae6abd0310a59847185c1cde84 121 Gene3D G3DSA:2.60.120.10 2 113 1.5E-8 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_22975 555c7d4513c619f5f72b045444610928 407 SUPERFAMILY SSF53335 69 250 2.26E-24 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_22975 555c7d4513c619f5f72b045444610928 407 Gene3D G3DSA:3.40.50.720 308 407 3.7E-40 T 14-10-2018 C2I25_22975 555c7d4513c619f5f72b045444610928 407 Pfam PF08484 C-methyltransferase C-terminal domain 243 400 1.4E-60 T 14-10-2018 IPR013691 C-methyltransferase C2I25_22975 555c7d4513c619f5f72b045444610928 407 Pfam PF13489 Methyltransferase domain 91 236 1.4E-16 T 14-10-2018 C2I25_22975 555c7d4513c619f5f72b045444610928 407 Pfam PF08421 Putative zinc binding domain 6 67 2.5E-22 T 14-10-2018 IPR013630 Methyltransferase putative zinc binding domain C2I25_22975 555c7d4513c619f5f72b045444610928 407 Gene3D G3DSA:3.40.50.150 60 254 7.3E-47 T 14-10-2018 C2I25_22975 555c7d4513c619f5f72b045444610928 407 Gene3D G3DSA:2.20.25.520 1 57 1.9E-20 T 14-10-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily C2I25_07225 68632ce5f1b154ae006d38cf711cc19b 287 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 77 1.3E-15 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 C2I25_07225 68632ce5f1b154ae006d38cf711cc19b 287 Gene3D G3DSA:3.40.50.10490 98 280 3.1E-44 T 14-10-2018 C2I25_07225 68632ce5f1b154ae006d38cf711cc19b 287 Pfam PF01380 SIS domain 130 259 4.9E-23 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I25_07225 68632ce5f1b154ae006d38cf711cc19b 287 SUPERFAMILY SSF53697 96 282 5.11E-42 T 14-10-2018 C2I25_07225 68632ce5f1b154ae006d38cf711cc19b 287 SUPERFAMILY SSF46689 5 77 4.66E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_07225 68632ce5f1b154ae006d38cf711cc19b 287 Gene3D G3DSA:1.10.10.10 2 79 3.0E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25610 613abe2f1b7aed4fee6b58e1588fd554 144 Pfam PF13673 Acetyltransferase (GNAT) domain 41 142 1.4E-18 T 14-10-2018 IPR000182 GNAT domain C2I25_25610 613abe2f1b7aed4fee6b58e1588fd554 144 Gene3D G3DSA:3.40.630.30 2 142 3.3E-40 T 14-10-2018 C2I25_25610 613abe2f1b7aed4fee6b58e1588fd554 144 SUPERFAMILY SSF55729 9 143 4.9E-33 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_28125 61f049d253aa7d8e2ade5a9a76d7ba10 90 Gene3D G3DSA:4.10.520.10 1 90 4.4E-40 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I25_28125 61f049d253aa7d8e2ade5a9a76d7ba10 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.0E-21 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_28125 61f049d253aa7d8e2ade5a9a76d7ba10 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.0E-21 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_28125 61f049d253aa7d8e2ade5a9a76d7ba10 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.0E-21 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_28125 61f049d253aa7d8e2ade5a9a76d7ba10 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 C2I25_28125 61f049d253aa7d8e2ade5a9a76d7ba10 90 SUPERFAMILY SSF47729 1 90 8.83E-35 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I25_28125 61f049d253aa7d8e2ade5a9a76d7ba10 90 SMART SM00411 1 90 5.2E-49 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_28125 61f049d253aa7d8e2ade5a9a76d7ba10 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.8E-36 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I25_08380 92a6fcb88f3c110e4577180c9a60d75f 188 Pfam PF00156 Phosphoribosyl transferase domain 69 148 4.3E-9 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_08380 92a6fcb88f3c110e4577180c9a60d75f 188 Gene3D G3DSA:3.40.50.2020 5 187 2.0E-46 T 14-10-2018 C2I25_08380 92a6fcb88f3c110e4577180c9a60d75f 188 SUPERFAMILY SSF53271 19 182 1.44E-38 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_08380 92a6fcb88f3c110e4577180c9a60d75f 188 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 188 22.109 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_08380 92a6fcb88f3c110e4577180c9a60d75f 188 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 25 178 3.7E-35 T 14-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_12345 c339992bea0e2c8a38e09fbd1e5ab93a 145 Pfam PF09148 Domain of unknown function (DUF1934) 13 139 7.1E-29 T 14-10-2018 IPR015231 Protein of unknown function DUF1934 C2I25_12345 c339992bea0e2c8a38e09fbd1e5ab93a 145 SUPERFAMILY SSF50814 7 143 1.62E-37 T 14-10-2018 IPR012674 Calycin C2I25_12345 c339992bea0e2c8a38e09fbd1e5ab93a 145 Gene3D G3DSA:2.40.128.20 2 145 1.1E-41 T 14-10-2018 IPR012674 Calycin C2I25_23005 c8b3eb1c7a13e99e0574a254b9203763 137 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 21 124 6.0E-46 T 14-10-2018 C2I25_23005 c8b3eb1c7a13e99e0574a254b9203763 137 Pfam PF03899 ATP synthase I chain 9 102 2.1E-12 T 14-10-2018 IPR005598 ATP synthase protein I C2I25_06285 ff49c8eadf251e9346276fd5c4d6a35b 149 Gene3D G3DSA:1.10.260.40 1 72 5.1E-24 T 14-10-2018 C2I25_06285 ff49c8eadf251e9346276fd5c4d6a35b 149 Pfam PF01381 Helix-turn-helix 7 61 1.4E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_06285 ff49c8eadf251e9346276fd5c4d6a35b 149 SUPERFAMILY SSF47413 1 67 6.66E-20 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_06285 ff49c8eadf251e9346276fd5c4d6a35b 149 SMART SM00530 6 61 3.0E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 SUPERFAMILY SSF54570 3 83 9.02E-35 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.013 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 8.0E-47 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 PIRSF PIRSF002144 1 92 3.7E-32 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.3E-25 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.3E-25 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.3E-25 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 Pfam PF00203 Ribosomal protein S19 3 83 4.0E-36 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10950 1905e41a7c02e04d00ea435ec0fe19c1 92 Gene3D G3DSA:3.30.860.10 1 92 1.3E-40 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_19880 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.023 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_19880 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 2.8E-28 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_19880 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 Pfam PF01783 Ribosomal L32p protein family 2 57 4.9E-27 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_19880 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 SUPERFAMILY SSF57829 1 55 5.31E-22 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 C2I25_20430 3aa78d13f5b5db907a649f7df0162c01 156 Gene3D G3DSA:2.30.30.180 88 154 5.1E-24 T 14-10-2018 C2I25_20430 3aa78d13f5b5db907a649f7df0162c01 156 SUPERFAMILY SSF74942 85 156 9.15E-22 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily C2I25_20430 3aa78d13f5b5db907a649f7df0162c01 156 Pfam PF17384 RimP C-terminal SH3 domain 87 156 1.7E-22 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal C2I25_20430 3aa78d13f5b5db907a649f7df0162c01 156 Pfam PF02576 RimP N-terminal domain 13 84 6.5E-28 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal C2I25_20430 3aa78d13f5b5db907a649f7df0162c01 156 SUPERFAMILY SSF75420 4 84 3.79E-26 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily C2I25_20430 3aa78d13f5b5db907a649f7df0162c01 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 24.677 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 C2I25_20430 3aa78d13f5b5db907a649f7df0162c01 156 Gene3D G3DSA:3.30.300.70 2 81 1.3E-29 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 SMART SM00388 355 423 4.3E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 SUPERFAMILY SSF55874 412 578 5.5E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 578 1.6E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 SUPERFAMILY SSF47384 350 423 7.46E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 Pfam PF00512 His Kinase A (phospho-acceptor) domain 356 414 1.3E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 SMART SM00387 469 580 1.3E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 Gene3D G3DSA:1.10.287.130 281 417 2.8E-12 T 14-10-2018 C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 Gene3D G3DSA:3.30.565.10 428 580 1.0E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 534 3.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 558 3.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 520 3.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_05815 7774dc68b4623bc64bbb265cac47e756 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 577 3.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27650 0c7095cf5bbcfc1c0543f4cae12c3c03 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_27650 0c7095cf5bbcfc1c0543f4cae12c3c03 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_27650 0c7095cf5bbcfc1c0543f4cae12c3c03 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 9.1E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_27650 0c7095cf5bbcfc1c0543f4cae12c3c03 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_27650 0c7095cf5bbcfc1c0543f4cae12c3c03 211 SUPERFAMILY SSF46689 6 69 1.5E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_27650 0c7095cf5bbcfc1c0543f4cae12c3c03 211 Gene3D G3DSA:1.10.357.10 2 204 1.5E-59 T 14-10-2018 C2I25_27650 0c7095cf5bbcfc1c0543f4cae12c3c03 211 SUPERFAMILY SSF48498 84 196 2.67E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_02160 51ae9a206f46a02f18462146b9e1db43 427 SMART SM01011 1 137 1.5E-36 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 C2I25_02160 51ae9a206f46a02f18462146b9e1db43 427 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 122 1.7E-30 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 C2I25_02160 51ae9a206f46a02f18462146b9e1db43 427 SUPERFAMILY SSF55920 173 417 1.83E-65 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I25_02160 51ae9a206f46a02f18462146b9e1db43 427 Gene3D G3DSA:3.40.350.10 1 171 9.8E-66 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I25_02160 51ae9a206f46a02f18462146b9e1db43 427 SUPERFAMILY SSF53092 2 172 4.13E-37 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I25_02160 51ae9a206f46a02f18462146b9e1db43 427 Gene3D G3DSA:3.90.230.10 172 427 1.9E-88 T 14-10-2018 C2I25_02160 51ae9a206f46a02f18462146b9e1db43 427 Pfam PF00557 Metallopeptidase family M24 179 391 8.3E-54 T 14-10-2018 IPR000994 Peptidase M24 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 169 188 9.6E-50 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 195 210 9.6E-50 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 46 67 9.6E-50 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 213 239 9.6E-50 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 251 268 9.6E-50 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 ProSitePatterns PS00091 Thymidylate synthase active site. 180 208 - T 14-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 SUPERFAMILY SSF55831 3 318 3.27E-139 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 Pfam PF00303 Thymidylate synthase 7 318 8.7E-122 T 14-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 318 1.0E-170 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 Gene3D G3DSA:3.30.572.10 3 318 3.9E-146 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_00275 8efe59999cf48844f7f6e9b298664a0d 318 Hamap MF_00008 Thymidylate synthase [thyA]. 5 318 40.786 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I25_22775 9e2f4378a8ce32cb1a76a051b902a22a 117 SMART SM00418 11 89 1.1E-24 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22775 9e2f4378a8ce32cb1a76a051b902a22a 117 Gene3D G3DSA:1.10.10.10 2 109 1.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22775 9e2f4378a8ce32cb1a76a051b902a22a 117 SUPERFAMILY SSF46785 3 87 8.37E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22775 9e2f4378a8ce32cb1a76a051b902a22a 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.1E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22775 9e2f4378a8ce32cb1a76a051b902a22a 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.1E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22775 9e2f4378a8ce32cb1a76a051b902a22a 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.1E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22775 9e2f4378a8ce32cb1a76a051b902a22a 117 Pfam PF01022 Bacterial regulatory protein, arsR family 19 62 2.5E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_06830 17bbba3c99f425449501f34a93673695 174 Pfam PF07366 SnoaL-like polyketide cyclase 58 165 1.0E-23 T 14-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 C2I25_06830 17bbba3c99f425449501f34a93673695 174 SUPERFAMILY SSF54427 53 164 1.03E-29 T 14-10-2018 IPR032710 NTF2-like domain superfamily C2I25_06830 17bbba3c99f425449501f34a93673695 174 Gene3D G3DSA:3.10.450.50 48 174 8.4E-45 T 14-10-2018 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 2.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 2.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 2.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.5E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 77 181 1.2E-12 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 Gene3D G3DSA:1.10.150.240 17 80 8.9E-53 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 1 214 48.155 T 14-10-2018 IPR023733 Pyrophosphatase PpaX GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 52 175 2.0E-14 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 6.8E-56 T 14-10-2018 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 Gene3D G3DSA:3.40.50.1000 6 201 8.9E-53 T 14-10-2018 IPR023214 HAD superfamily C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 6 179 1.2E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_13420 cd4817f0f1179618f243c2773f411ee6 216 SUPERFAMILY SSF56784 1 213 1.21E-58 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_14930 a60b874f8e1377f3bc6cf4f637fd9fb7 286 Gene3D G3DSA:3.30.200.180 50 284 2.1E-80 T 14-10-2018 C2I25_14930 a60b874f8e1377f3bc6cf4f637fd9fb7 286 Gene3D G3DSA:3.30.1380.10 68 211 2.1E-80 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_14930 a60b874f8e1377f3bc6cf4f637fd9fb7 286 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 98 213 4.9E-29 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 C2I25_14930 a60b874f8e1377f3bc6cf4f637fd9fb7 286 SUPERFAMILY SSF55166 92 222 1.39E-28 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_07180 c69cef72184db2b4e67b3d619f53976c 151 Pfam PF00583 Acetyltransferase (GNAT) family 40 116 3.0E-13 T 14-10-2018 IPR000182 GNAT domain C2I25_07180 c69cef72184db2b4e67b3d619f53976c 151 SUPERFAMILY SSF55729 1 149 2.95E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_07180 c69cef72184db2b4e67b3d619f53976c 151 Gene3D G3DSA:3.40.630.30 2 142 2.7E-29 T 14-10-2018 C2I25_17635 c0400f33f5fbfc752fe0efbd1c234ee9 275 SUPERFAMILY SSF51735 2 159 5.12E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_17635 c0400f33f5fbfc752fe0efbd1c234ee9 275 Gene3D G3DSA:1.10.3730.10 161 262 8.2E-17 T 14-10-2018 C2I25_17635 c0400f33f5fbfc752fe0efbd1c234ee9 275 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_17635 c0400f33f5fbfc752fe0efbd1c234ee9 275 Gene3D G3DSA:3.40.50.720 1 160 1.1E-30 T 14-10-2018 C2I25_17635 c0400f33f5fbfc752fe0efbd1c234ee9 275 PIRSF PIRSF000193 1 265 2.2E-65 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_17635 c0400f33f5fbfc752fe0efbd1c234ee9 275 SUPERFAMILY SSF48179 158 262 1.02E-19 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_17635 c0400f33f5fbfc752fe0efbd1c234ee9 275 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 5.9E-15 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I25_17635 c0400f33f5fbfc752fe0efbd1c234ee9 275 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 260 5.9E-17 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_21015 7fc373bc9ab363f61224d54ea3dcb743 107 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 9.1E-22 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_21015 7fc373bc9ab363f61224d54ea3dcb743 107 Gene3D G3DSA:1.10.10.10 2 106 2.6E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_21015 7fc373bc9ab363f61224d54ea3dcb743 107 SUPERFAMILY SSF46785 10 103 3.91E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19250 ca85d1a22d532ccf9db35ef6868d7147 431 Pfam PF00990 Diguanylate cyclase, GGDEF domain 269 422 4.7E-45 T 14-10-2018 IPR000160 GGDEF domain C2I25_19250 ca85d1a22d532ccf9db35ef6868d7147 431 SMART SM00267 258 426 3.5E-58 T 14-10-2018 IPR000160 GGDEF domain C2I25_19250 ca85d1a22d532ccf9db35ef6868d7147 431 Pfam PF13188 PAS domain 145 180 0.0014 T 14-10-2018 IPR000014 PAS domain C2I25_19250 ca85d1a22d532ccf9db35ef6868d7147 431 Gene3D G3DSA:3.30.70.270 255 429 6.9E-52 T 14-10-2018 C2I25_19250 ca85d1a22d532ccf9db35ef6868d7147 431 SUPERFAMILY SSF55073 274 428 1.1E-45 T 14-10-2018 IPR029787 Nucleotide cyclase C2I25_19250 ca85d1a22d532ccf9db35ef6868d7147 431 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 266 425 7.6E-47 T 14-10-2018 IPR000160 GGDEF domain C2I25_09925 1f866055a81c0e5e5e7d3e0e1894ef4a 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 236 1.6E-78 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 C2I25_09925 1f866055a81c0e5e5e7d3e0e1894ef4a 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09925 1f866055a81c0e5e5e7d3e0e1894ef4a 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09925 1f866055a81c0e5e5e7d3e0e1894ef4a 239 SUPERFAMILY SSF56104 1 236 1.37E-85 T 14-10-2018 C2I25_09925 1f866055a81c0e5e5e7d3e0e1894ef4a 239 Pfam PF01259 SAICAR synthetase 7 232 4.4E-68 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09925 1f866055a81c0e5e5e7d3e0e1894ef4a 239 Gene3D G3DSA:3.30.200.20 7 232 3.1E-97 T 14-10-2018 C2I25_09925 1f866055a81c0e5e5e7d3e0e1894ef4a 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 34.32 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09925 1f866055a81c0e5e5e7d3e0e1894ef4a 239 Gene3D G3DSA:3.30.470.20 85 221 3.1E-97 T 14-10-2018 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 Pfam PF01245 Ribosomal protein L19 4 112 3.0E-53 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 PIRSF PIRSF002191 1 114 3.3E-51 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 Gene3D G3DSA:2.30.30.790 9 114 1.3E-15 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 3 114 32.208 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 SUPERFAMILY SSF50104 2 113 1.1E-48 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 2.5E-51 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20310 2c011d0aa596b824045bf8e2be261b34 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17560 f5485016ac08d56a766572da659aa879 207 Gene3D G3DSA:3.40.109.10 1 205 3.0E-56 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_17560 f5485016ac08d56a766572da659aa879 207 SUPERFAMILY SSF55469 2 204 8.9E-51 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_17560 f5485016ac08d56a766572da659aa879 207 Pfam PF00881 Nitroreductase family 9 183 2.8E-22 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_27920 f53c5d555c0f716cc6d3d1ab93768617 61 Pfam PF14169 Cold-inducible protein YdjO 4 60 2.2E-28 T 14-10-2018 IPR025916 Cold-inducible protein YdjO C2I25_06905 4540c209cdc295a17dd3b673e7890de3 349 Gene3D G3DSA:3.40.630.10 14 342 1.4E-134 T 14-10-2018 C2I25_06905 4540c209cdc295a17dd3b673e7890de3 349 SUPERFAMILY SSF101821 74 186 4.43E-33 T 14-10-2018 C2I25_06905 4540c209cdc295a17dd3b673e7890de3 349 Gene3D G3DSA:2.40.30.40 77 171 1.4E-134 T 14-10-2018 IPR023367 Peptidase M42, domain 2 C2I25_06905 4540c209cdc295a17dd3b673e7890de3 349 SUPERFAMILY SSF53187 6 343 7.22E-56 T 14-10-2018 C2I25_06905 4540c209cdc295a17dd3b673e7890de3 349 PIRSF PIRSF001123 5 345 1.5E-42 T 14-10-2018 IPR008007 Peptidase M42 C2I25_06905 4540c209cdc295a17dd3b673e7890de3 349 Pfam PF05343 M42 glutamyl aminopeptidase 49 337 3.0E-90 T 14-10-2018 IPR008007 Peptidase M42 C2I25_25040 e0037ec48a5c94f00ca8478c2498a74c 126 SMART SM00345 15 74 0.0046 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_25040 e0037ec48a5c94f00ca8478c2498a74c 126 Gene3D G3DSA:1.10.10.10 10 125 2.4E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25040 e0037ec48a5c94f00ca8478c2498a74c 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.3E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_25040 e0037ec48a5c94f00ca8478c2498a74c 126 SUPERFAMILY SSF46785 8 81 2.61E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08390 7515cab4a0a5bc714e68226c8305351e 396 Gene3D G3DSA:3.90.1150.10 38 387 2.0E-135 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_08390 7515cab4a0a5bc714e68226c8305351e 396 Pfam PF00155 Aminotransferase class I and II 43 384 2.6E-62 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_08390 7515cab4a0a5bc714e68226c8305351e 396 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 396 1.6E-191 T 14-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type C2I25_08390 7515cab4a0a5bc714e68226c8305351e 396 SUPERFAMILY SSF53383 8 394 1.5E-108 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_08390 7515cab4a0a5bc714e68226c8305351e 396 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 C2I25_08390 7515cab4a0a5bc714e68226c8305351e 396 Gene3D G3DSA:3.40.640.10 58 294 2.0E-135 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_12795 3d4711f936370bda02541cd330200bf0 227 Gene3D G3DSA:3.40.50.300 2 227 1.1E-74 T 14-10-2018 C2I25_12795 3d4711f936370bda02541cd330200bf0 227 Pfam PF13614 AAA domain 48 189 1.4E-13 T 14-10-2018 IPR025669 AAA domain C2I25_12795 3d4711f936370bda02541cd330200bf0 227 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 27 227 4.3E-70 T 14-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 C2I25_12795 3d4711f936370bda02541cd330200bf0 227 SUPERFAMILY SSF52540 46 220 1.05E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02690 b83856e311781ff0321f02b882ea72dd 443 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 106 120 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 C2I25_02690 b83856e311781ff0321f02b882ea72dd 443 SUPERFAMILY SSF53686 48 436 5.76E-59 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_02690 b83856e311781ff0321f02b882ea72dd 443 Gene3D G3DSA:3.40.50.1100 114 236 1.7E-201 T 14-10-2018 C2I25_02690 b83856e311781ff0321f02b882ea72dd 443 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 73 404 1.4E-57 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_02690 b83856e311781ff0321f02b882ea72dd 443 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 9 434 1.4E-224 T 14-10-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 C2I25_02690 b83856e311781ff0321f02b882ea72dd 443 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 443 262.444 T 14-10-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 C2I25_02690 b83856e311781ff0321f02b882ea72dd 443 Gene3D G3DSA:3.40.50.1100 22 434 1.7E-201 T 14-10-2018 C2I25_13695 60fce0e27e54a3c3ef125f87c4c2467b 144 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 13 131 19.413 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I25_13695 60fce0e27e54a3c3ef125f87c4c2467b 144 TIGRFAM TIGR00494 crcB: protein CrcB 15 129 2.7E-27 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I25_13695 60fce0e27e54a3c3ef125f87c4c2467b 144 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 15 126 5.0E-24 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I25_22440 43c2f30118eef0f5c735498516983570 250 Pfam PF00753 Metallo-beta-lactamase superfamily 33 235 3.0E-33 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_22440 43c2f30118eef0f5c735498516983570 250 SMART SM00849 34 235 1.6E-24 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_22440 43c2f30118eef0f5c735498516983570 250 Gene3D G3DSA:3.60.15.10 1 241 1.5E-99 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_22440 43c2f30118eef0f5c735498516983570 250 SUPERFAMILY SSF56281 24 236 6.29E-38 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_01680 9fc288f07403425956a4baaef84efef5 417 Gene3D G3DSA:1.20.1250.20 9 403 9.9E-64 T 14-10-2018 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 SUPERFAMILY SSF103473 16 404 4.19E-64 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_01680 9fc288f07403425956a4baaef84efef5 417 Pfam PF07690 Major Facilitator Superfamily 25 283 8.6E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 Pfam PF07690 Major Facilitator Superfamily 291 410 2.5E-15 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 ProSitePatterns PS00216 Sugar transport proteins signature 1. 70 86 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 PRINTS PR01035 Tetracycline resistance protein signature 290 311 1.4E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 PRINTS PR01035 Tetracycline resistance protein signature 26 42 1.4E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 PRINTS PR01035 Tetracycline resistance protein signature 147 169 1.4E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 PRINTS PR01035 Tetracycline resistance protein signature 175 195 1.4E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 PRINTS PR01035 Tetracycline resistance protein signature 347 370 1.4E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_01680 9fc288f07403425956a4baaef84efef5 417 ProSitePatterns PS00217 Sugar transport proteins signature 2. 323 348 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 Gene3D G3DSA:3.50.50.60 26 425 2.3E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 SUPERFAMILY SSF51905 23 477 8.63E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 Gene3D G3DSA:3.90.660.10 24 415 2.3E-97 T 14-10-2018 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 PRINTS PR00757 Flavin-containing amine oxidase signature 407 426 1.9E-11 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 PRINTS PR00757 Flavin-containing amine oxidase signature 457 474 1.9E-11 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 PRINTS PR00757 Flavin-containing amine oxidase signature 26 45 1.9E-11 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 PRINTS PR00757 Flavin-containing amine oxidase signature 320 339 1.9E-11 T 14-10-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 SUPERFAMILY SSF54373 316 426 4.38E-33 T 14-10-2018 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 Gene3D G3DSA:1.10.405.10 122 225 2.3E-97 T 14-10-2018 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 Gene3D G3DSA:1.10.10.1620 432 478 5.0E-19 T 14-10-2018 C2I25_01990 5192e1e926e3fe09f4bf48a4cc6248cf 478 Pfam PF01593 Flavin containing amine oxidoreductase 34 475 2.7E-65 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 PRINTS PR00175 Sodium/alanine symporter signature 204 223 3.2E-58 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 PRINTS PR00175 Sodium/alanine symporter signature 353 375 3.2E-58 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 PRINTS PR00175 Sodium/alanine symporter signature 295 313 3.2E-58 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 PRINTS PR00175 Sodium/alanine symporter signature 176 194 3.2E-58 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 PRINTS PR00175 Sodium/alanine symporter signature 86 108 3.2E-58 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 PRINTS PR00175 Sodium/alanine symporter signature 416 436 3.2E-58 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 447 1.3E-142 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_25430 a65ea2fa17b5bdb9cdee54869821efc8 496 Pfam PF01235 Sodium:alanine symporter family 49 459 9.3E-153 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 SUPERFAMILY SSF54719 90 201 1.7E-47 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 198 6.1E-42 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 SUPERFAMILY SSF46609 2 92 4.45E-38 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 Gene3D G3DSA:2.40.500.20 92 203 5.7E-51 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 PIRSF PIRSF000349 1 203 4.3E-86 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 91 5.6E-33 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.2E-27 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 1.2E-27 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 1.2E-27 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.2E-27 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 1.2E-27 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_17910 22a054e16c44615fbab98b5100c816fe 203 Gene3D G3DSA:1.10.287.990 21 91 2.4E-32 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_12705 e2fd3e92a2b45763e92b539796052a99 139 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 122 1.1E-34 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12705 e2fd3e92a2b45763e92b539796052a99 139 Gene3D G3DSA:3.30.70.3270 24 139 7.6E-33 T 14-10-2018 C2I25_12705 e2fd3e92a2b45763e92b539796052a99 139 SUPERFAMILY SSF54862 24 125 2.18E-24 T 14-10-2018 C2I25_12705 e2fd3e92a2b45763e92b539796052a99 139 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I25_12705 e2fd3e92a2b45763e92b539796052a99 139 Pfam PF12838 4Fe-4S dicluster domain 45 102 2.4E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_25795 ad67204c6273a1fcf7a96af8b45691c7 203 SUPERFAMILY SSF48498 90 202 6.04E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_25795 ad67204c6273a1fcf7a96af8b45691c7 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 6.3E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_25795 ad67204c6273a1fcf7a96af8b45691c7 203 Gene3D G3DSA:1.10.10.60 3 62 1.7E-12 T 14-10-2018 C2I25_25795 ad67204c6273a1fcf7a96af8b45691c7 203 Gene3D G3DSA:1.10.357.10 63 203 5.2E-29 T 14-10-2018 C2I25_25795 ad67204c6273a1fcf7a96af8b45691c7 203 SUPERFAMILY SSF46689 8 80 9.23E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_22270 f5a9149ec72723f3026e095eb6350c13 348 SUPERFAMILY SSF55909 9 346 6.6E-103 T 14-10-2018 C2I25_22270 f5a9149ec72723f3026e095eb6350c13 348 Gene3D G3DSA:3.75.10.10 4 348 4.2E-111 T 14-10-2018 C2I25_22270 f5a9149ec72723f3026e095eb6350c13 348 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 11 345 4.6E-99 T 14-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 C2I25_13710 ae15906378ab27d7c954828d657417cb 134 Gene3D G3DSA:2.170.270.10 1 117 3.9E-30 T 14-10-2018 C2I25_13710 ae15906378ab27d7c954828d657417cb 134 Pfam PF00856 SET domain 19 114 2.0E-15 T 14-10-2018 IPR001214 SET domain GO:0005515 C2I25_13710 ae15906378ab27d7c954828d657417cb 134 SUPERFAMILY SSF82199 15 116 1.96E-23 T 14-10-2018 C2I25_13710 ae15906378ab27d7c954828d657417cb 134 SMART SM00317 3 120 5.2E-9 T 14-10-2018 IPR001214 SET domain GO:0005515 C2I25_13710 ae15906378ab27d7c954828d657417cb 134 PIRSF PIRSF022536 2 134 8.6E-33 T 14-10-2018 IPR009207 Histone methyltransferase, PBCV type putative KEGG: 00310+2.1.1.43 C2I25_15015 19e3241a7181578c4c8cb58349417326 270 Pfam PF13786 Domain of unknown function (DUF4179) 36 123 1.4E-7 T 14-10-2018 IPR025436 Domain of unknown function DUF4179 C2I25_27340 1696926a43b9176075de6f06b479ecb1 397 Gene3D G3DSA:3.30.300.210 240 394 3.4E-43 T 14-10-2018 IPR038501 Spore germination GerAC superfamily C2I25_27340 1696926a43b9176075de6f06b479ecb1 397 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 11 393 1.8E-96 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_27340 1696926a43b9176075de6f06b479ecb1 397 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 224 391 1.6E-37 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_06385 845c218d6f3057aef1bed45b85d493c9 103 Pfam PF01906 Putative heavy-metal-binding 1 103 6.2E-38 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 C2I25_06385 845c218d6f3057aef1bed45b85d493c9 103 Gene3D G3DSA:3.30.110.70 1 103 6.3E-44 T 14-10-2018 C2I25_06385 845c218d6f3057aef1bed45b85d493c9 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.629 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 C2I25_06385 845c218d6f3057aef1bed45b85d493c9 103 SUPERFAMILY SSF117782 1 103 1.28E-36 T 14-10-2018 IPR035439 UPF0145 domain superfamily C2I25_03760 afa0449136f975de688f99dc0c51ea59 227 Pfam PF04298 Putative neutral zinc metallopeptidase 4 219 9.7E-94 T 14-10-2018 IPR007395 Putative neutral zinc metallopeptidase C2I25_12990 3b90f8dca3afbabd167e7d4dfe5ef1e9 100 Pfam PF13049 Protein of unknown function (DUF3910) 1 93 4.2E-66 T 14-10-2018 IPR025021 Protein of unknown function DUF3910 C2I25_04970 d7276c09de4c4a31720dfef31acb8154 205 SUPERFAMILY SSF48317 5 194 7.06E-34 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I25_04970 d7276c09de4c4a31720dfef31acb8154 205 Pfam PF01569 PAP2 superfamily 82 192 8.1E-18 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_04970 d7276c09de4c4a31720dfef31acb8154 205 Gene3D G3DSA:1.20.144.10 108 205 1.6E-22 T 14-10-2018 C2I25_04970 d7276c09de4c4a31720dfef31acb8154 205 Gene3D G3DSA:1.20.144.10 1 107 1.5E-9 T 14-10-2018 C2I25_04970 d7276c09de4c4a31720dfef31acb8154 205 SMART SM00014 77 189 1.1E-22 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_04390 bb2cf9027fbbad9a6f6bdb4449505583 194 Gene3D G3DSA:3.20.19.10 1 172 1.7E-76 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 C2I25_04390 bb2cf9027fbbad9a6f6bdb4449505583 194 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 194 40.352 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 C2I25_04390 bb2cf9027fbbad9a6f6bdb4449505583 194 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 2 184 1.6E-73 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 C2I25_04390 bb2cf9027fbbad9a6f6bdb4449505583 194 Pfam PF00694 Aconitase C-terminal domain 2 123 7.7E-36 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 C2I25_04390 bb2cf9027fbbad9a6f6bdb4449505583 194 SUPERFAMILY SSF52016 2 189 4.12E-60 T 14-10-2018 C2I25_21760 3b6ce9d89c060b0fada876ef6ca6ddbf 78 SUPERFAMILY SSF54285 1 78 2.18E-16 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp C2I25_21760 3b6ce9d89c060b0fada876ef6ca6ddbf 78 Gene3D G3DSA:3.10.20.30 1 78 3.5E-20 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_21760 3b6ce9d89c060b0fada876ef6ca6ddbf 78 Pfam PF02597 ThiS family 4 78 2.2E-18 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 C2I25_21760 3b6ce9d89c060b0fada876ef6ca6ddbf 78 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 78 7.9E-23 T 14-10-2018 C2I25_19425 5c5d430f0e2f95a8a3be9b75551b24d4 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 273 3.0E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_19425 5c5d430f0e2f95a8a3be9b75551b24d4 280 SUPERFAMILY SSF161098 6 280 6.26E-70 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_19425 5c5d430f0e2f95a8a3be9b75551b24d4 280 Gene3D G3DSA:1.10.3720.10 1 267 2.4E-66 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 SUPERFAMILY SSF54001 463 581 4.71E-33 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Pfam PF00877 NlpC/P60 family 478 579 6.1E-26 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Gene3D G3DSA:3.90.1720.10 429 577 1.4E-35 T 14-10-2018 C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Gene3D G3DSA:2.30.30.40 203 260 4.0E-18 T 14-10-2018 C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Gene3D G3DSA:2.30.30.40 36 107 1.7E-16 T 14-10-2018 C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 SMART SM00287 287 348 2.4E-7 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 SMART SM00287 117 178 5.7E-13 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 SMART SM00287 369 431 1.5E-14 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 SMART SM00287 202 264 1.1E-12 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 SMART SM00287 46 107 1.8E-8 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Pfam PF08239 Bacterial SH3 domain 296 345 9.3E-12 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Pfam PF08239 Bacterial SH3 domain 126 176 2.0E-14 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Pfam PF08239 Bacterial SH3 domain 54 105 6.0E-12 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Pfam PF08239 Bacterial SH3 domain 377 428 3.5E-15 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Pfam PF08239 Bacterial SH3 domain 210 260 1.4E-13 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Gene3D G3DSA:2.30.30.40 371 428 3.9E-19 T 14-10-2018 C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Gene3D G3DSA:2.30.30.40 288 351 1.4E-15 T 14-10-2018 C2I25_13030 4e0ee7a55a83466c4cb0722a11747a25 583 Gene3D G3DSA:2.30.30.40 119 182 1.1E-15 T 14-10-2018 C2I25_16710 3d0b7c8fe2d405d8b21a5ae5c07205fc 257 SMART SM00893 21 211 9.0E-54 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 C2I25_16710 3d0b7c8fe2d405d8b21a5ae5c07205fc 257 SUPERFAMILY SSF52402 1 246 6.51E-73 T 14-10-2018 C2I25_16710 3d0b7c8fe2d405d8b21a5ae5c07205fc 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 C2I25_16710 3d0b7c8fe2d405d8b21a5ae5c07205fc 257 Gene3D G3DSA:3.40.50.620 1 256 4.5E-81 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_16710 3d0b7c8fe2d405d8b21a5ae5c07205fc 257 PIRSF PIRSF000090 1 257 2.4E-74 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 C2I25_16710 3d0b7c8fe2d405d8b21a5ae5c07205fc 257 Pfam PF01012 Electron transfer flavoprotein domain 28 206 2.5E-46 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 Gene3D G3DSA:1.20.1250.20 11 194 8.5E-34 T 14-10-2018 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 Gene3D G3DSA:1.20.1250.20 248 438 6.7E-18 T 14-10-2018 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 8.0E-27 T 14-10-2018 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 8.0E-27 T 14-10-2018 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 8.0E-27 T 14-10-2018 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 222 240 8.0E-27 T 14-10-2018 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 291 315 8.0E-27 T 14-10-2018 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 161 185 8.0E-27 T 14-10-2018 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 Pfam PF07690 Major Facilitator Superfamily 16 398 1.6E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_16845 46856d9ea05fe438412d929c0ee12231 441 SUPERFAMILY SSF103473 12 433 1.44E-60 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_13265 dadf6c5d3c58831bea2173ea53733f4d 435 Gene3D G3DSA:3.90.1720.10 233 429 1.2E-35 T 14-10-2018 C2I25_13265 dadf6c5d3c58831bea2173ea53733f4d 435 SUPERFAMILY SSF54001 316 435 1.37E-30 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_13265 dadf6c5d3c58831bea2173ea53733f4d 435 Pfam PF00877 NlpC/P60 family 334 432 7.4E-22 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I25_06065 59978736a9bebef1c0e9be6589b4c78b 472 Pfam PF03703 Bacterial PH domain 238 321 8.0E-12 T 14-10-2018 IPR005182 Domain of unknown function DUF304 C2I25_06065 59978736a9bebef1c0e9be6589b4c78b 472 Pfam PF03703 Bacterial PH domain 59 129 1.6E-15 T 14-10-2018 IPR005182 Domain of unknown function DUF304 C2I25_06065 59978736a9bebef1c0e9be6589b4c78b 472 Pfam PF03703 Bacterial PH domain 391 464 8.4E-9 T 14-10-2018 IPR005182 Domain of unknown function DUF304 C2I25_06065 59978736a9bebef1c0e9be6589b4c78b 472 PIRSF PIRSF026631 1 472 2.0E-137 T 14-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 C2I25_25975 cdb28681fd193cded12f8a32ff673f94 221 SMART SM00448 4 114 5.7E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_25975 cdb28681fd193cded12f8a32ff673f94 221 Gene3D G3DSA:3.40.50.2300 1 126 7.8E-41 T 14-10-2018 C2I25_25975 cdb28681fd193cded12f8a32ff673f94 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 219 1.7E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_25975 cdb28681fd193cded12f8a32ff673f94 221 Gene3D G3DSA:1.10.10.10 127 221 1.5E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25975 cdb28681fd193cded12f8a32ff673f94 221 Pfam PF00072 Response regulator receiver domain 6 114 9.1E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_25975 cdb28681fd193cded12f8a32ff673f94 221 SMART SM00862 148 219 4.7E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_25975 cdb28681fd193cded12f8a32ff673f94 221 SUPERFAMILY SSF52172 1 180 3.27E-44 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 SMART SM00843 1338 1403 7.5E-37 T 14-10-2018 IPR018541 FtsK gamma domain C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 Pfam PF01580 FtsK/SpoIIIE family 1051 1186 3.5E-47 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 Pfam PF01580 FtsK/SpoIIIE family 1192 1243 1.1E-15 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 Gene3D G3DSA:3.30.980.40 944 1047 3.2E-36 T 14-10-2018 C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 Pfam PF09397 Ftsk gamma domain 1340 1400 2.6E-27 T 14-10-2018 IPR018541 FtsK gamma domain C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 Gene3D G3DSA:3.40.50.300 1048 1327 5.0E-112 T 14-10-2018 C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 SUPERFAMILY SSF46785 1339 1404 7.62E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 SMART SM00382 1086 1264 0.0078 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 Gene3D G3DSA:1.10.10.10 1332 1399 8.2E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15810 8299bdf73abb18cac8ce0c9f2d57f9c3 1413 SUPERFAMILY SSF52540 1024 1316 5.66E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_14450 fcc2607e2d75ba2bea220700eb1e423c 117 Gene3D G3DSA:2.60.300.12 1 109 7.8E-34 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I25_14450 fcc2607e2d75ba2bea220700eb1e423c 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 1.4E-34 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 C2I25_14450 fcc2607e2d75ba2bea220700eb1e423c 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 C2I25_14450 fcc2607e2d75ba2bea220700eb1e423c 117 SUPERFAMILY SSF89360 1 95 8.04E-26 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I25_14450 fcc2607e2d75ba2bea220700eb1e423c 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 102 5.6E-19 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 SUPERFAMILY SSF81296 41 209 5.46E-58 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 SUPERFAMILY SSF51055 407 440 1.27E-5 T 14-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 Gene3D G3DSA:2.60.40.10 312 402 8.8E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 Gene3D G3DSA:2.60.40.10 218 304 2.3E-24 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 Gene3D G3DSA:2.70.50.50 41 210 4.1E-68 T 14-10-2018 C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 SUPERFAMILY SSF49265 219 403 9.02E-29 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 Gene3D G3DSA:2.10.10.20 408 455 2.3E-6 T 14-10-2018 C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 SMART SM00495 409 455 0.0077 T 14-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 SMART SM00060 314 391 1.1E-6 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 SMART SM00060 220 293 5.1E-8 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 41 207 1.3E-39 T 14-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal C2I25_25605 7338a183dc0fdedda993895e1b34917a 455 Pfam PF00041 Fibronectin type III domain 316 391 1.2E-8 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_22995 8976f3e085ab5197cf9632a5d7a84a8d 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 4.3E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_22995 8976f3e085ab5197cf9632a5d7a84a8d 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 4.3E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_22995 8976f3e085ab5197cf9632a5d7a84a8d 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 4.3E-5 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_22995 8976f3e085ab5197cf9632a5d7a84a8d 135 SUPERFAMILY SSF46955 2 109 5.13E-21 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_22995 8976f3e085ab5197cf9632a5d7a84a8d 135 Gene3D G3DSA:1.10.1660.10 1 129 8.4E-24 T 14-10-2018 C2I25_22995 8976f3e085ab5197cf9632a5d7a84a8d 135 SMART SM00422 2 70 1.1E-19 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_22995 8976f3e085ab5197cf9632a5d7a84a8d 135 Pfam PF13411 MerR HTH family regulatory protein 2 69 1.3E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_22520 408e74d68d2a2baebe8c7772a3e8f177 106 Pfam PF03551 Transcriptional regulator PadR-like family 16 87 1.7E-23 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_22520 408e74d68d2a2baebe8c7772a3e8f177 106 Gene3D G3DSA:1.10.10.10 1 106 4.2E-40 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22520 408e74d68d2a2baebe8c7772a3e8f177 106 SUPERFAMILY SSF46785 5 99 2.39E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01520 ffceb0fb8cc41d02b4e5b41153c56e94 194 Pfam PF13302 Acetyltransferase (GNAT) domain 16 159 2.7E-25 T 14-10-2018 IPR000182 GNAT domain C2I25_01520 ffceb0fb8cc41d02b4e5b41153c56e94 194 Gene3D G3DSA:3.40.630.30 10 185 8.9E-41 T 14-10-2018 C2I25_01520 ffceb0fb8cc41d02b4e5b41153c56e94 194 SUPERFAMILY SSF55729 10 185 8.86E-40 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_00225 eec55f0126b3ea039f98ff27eff01287 280 Gene3D G3DSA:3.40.50.10170 1 152 2.1E-55 T 14-10-2018 C2I25_00225 eec55f0126b3ea039f98ff27eff01287 280 SUPERFAMILY SSF82549 1 279 1.07E-94 T 14-10-2018 C2I25_00225 eec55f0126b3ea039f98ff27eff01287 280 Gene3D G3DSA:3.30.1180.10 153 279 4.5E-37 T 14-10-2018 C2I25_00225 eec55f0126b3ea039f98ff27eff01287 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 4.1E-94 T 14-10-2018 IPR003797 DegV C2I25_00225 eec55f0126b3ea039f98ff27eff01287 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 3.3E-104 T 14-10-2018 IPR003797 DegV C2I25_28565 83be259296ab853f87b5c4e09ce1a75d 608 Pfam PF07728 AAA domain (dynein-related subfamily) 284 436 4.3E-7 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 C2I25_28565 83be259296ab853f87b5c4e09ce1a75d 608 Gene3D G3DSA:3.40.50.300 267 448 1.2E-15 T 14-10-2018 C2I25_28565 83be259296ab853f87b5c4e09ce1a75d 608 SUPERFAMILY SSF52540 280 447 5.4E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_28520 83be259296ab853f87b5c4e09ce1a75d 608 Pfam PF07728 AAA domain (dynein-related subfamily) 284 436 4.3E-7 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 C2I25_28520 83be259296ab853f87b5c4e09ce1a75d 608 Gene3D G3DSA:3.40.50.300 267 448 1.2E-15 T 14-10-2018 C2I25_28520 83be259296ab853f87b5c4e09ce1a75d 608 SUPERFAMILY SSF52540 280 447 5.4E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_06780 34adf37947090fc01825518ad17bf941 463 Gene3D G3DSA:3.40.600.10 223 462 2.3E-64 T 14-10-2018 IPR037057 DNA mismatch repair MutH/Restriction endonuclease, type II superfamily GO:0003677|GO:0004519 C2I25_06780 34adf37947090fc01825518ad17bf941 463 SMART SM00927 50 150 2.4E-31 T 14-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 C2I25_06780 34adf37947090fc01825518ad17bf941 463 Pfam PF02976 DNA mismatch repair enzyme MutH 48 150 5.0E-35 T 14-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 C2I25_06780 34adf37947090fc01825518ad17bf941 463 Pfam PF02976 DNA mismatch repair enzyme MutH 288 372 1.3E-6 T 14-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 C2I25_06780 34adf37947090fc01825518ad17bf941 463 SUPERFAMILY SSF52980 231 460 9.12E-38 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I25_06780 34adf37947090fc01825518ad17bf941 463 SUPERFAMILY SSF52980 2 216 8.04E-58 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I25_06780 34adf37947090fc01825518ad17bf941 463 Gene3D G3DSA:3.40.600.10 1 219 1.2E-73 T 14-10-2018 IPR037057 DNA mismatch repair MutH/Restriction endonuclease, type II superfamily GO:0003677|GO:0004519 C2I25_02640 4d46509759b8dc3b697c0993ad513716 369 Pfam PF12698 ABC-2 family transporter protein 19 360 2.7E-29 T 14-10-2018 C2I25_14305 a426e0dd2971205148f2510334270868 254 Pfam PF13242 HAD-hyrolase-like 177 249 1.1E-21 T 14-10-2018 C2I25_14305 a426e0dd2971205148f2510334270868 254 Gene3D G3DSA:3.40.50.1000 4 240 5.5E-89 T 14-10-2018 IPR023214 HAD superfamily C2I25_14305 a426e0dd2971205148f2510334270868 254 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 226 4.1E-42 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA C2I25_14305 a426e0dd2971205148f2510334270868 254 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 2 250 6.5E-125 T 14-10-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 C2I25_14305 a426e0dd2971205148f2510334270868 254 Gene3D G3DSA:3.40.50.1000 82 177 5.5E-89 T 14-10-2018 IPR023214 HAD superfamily C2I25_14305 a426e0dd2971205148f2510334270868 254 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 105 2.6E-27 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA C2I25_14305 a426e0dd2971205148f2510334270868 254 PIRSF PIRSF000915 1 113 2.5E-26 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA C2I25_14305 a426e0dd2971205148f2510334270868 254 PIRSF PIRSF000915 108 253 1.6E-34 T 14-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA C2I25_14305 a426e0dd2971205148f2510334270868 254 SUPERFAMILY SSF56784 1 251 1.68E-76 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 SUPERFAMILY SSF50447 362 444 5.82E-25 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 ProSitePatterns PS01176 Initiation factor 2 signature. 641 663 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Pfam PF11987 Translation-initiation factor 2 475 580 1.5E-37 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 688 17.515 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:3.40.50.10050 484 591 2.8E-38 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:3.40.50.300 187 361 1.2E-75 T 14-10-2018 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 106 688 5.1E-278 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:1.10.10.2480 1 91 1.2E-11 T 14-10-2018 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 SUPERFAMILY SSF50447 591 688 1.85E-33 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:2.40.30.10 592 688 9.0E-36 T 14-10-2018 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 SUPERFAMILY SSF52156 469 597 8.63E-39 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:2.40.30.10 362 479 3.0E-40 T 14-10-2018 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 2.0E-14 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 115 163 5.9E-16 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 192 349 4.0E-38 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 Pfam PF00009 Elongation factor Tu GTP binding domain 195 350 3.3E-37 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I25_20450 ca5d3ebb957af41168b4e945c8f499a2 688 SUPERFAMILY SSF52540 178 362 1.7E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18555 ce58049b75b9ec76580d529046aa32d7 48 Pfam PF14174 YycC-like protein 1 47 1.2E-28 T 14-10-2018 IPR025550 YycC-like protein C2I25_21400 8007750a01c3784adcd792eaa74e548c 226 Gene3D G3DSA:1.10.10.10 130 226 1.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_21400 8007750a01c3784adcd792eaa74e548c 226 SMART SM00448 3 112 1.1E-40 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_21400 8007750a01c3784adcd792eaa74e548c 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 1.3E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_21400 8007750a01c3784adcd792eaa74e548c 226 SUPERFAMILY SSF52172 4 179 1.57E-39 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_21400 8007750a01c3784adcd792eaa74e548c 226 Gene3D G3DSA:3.40.50.2300 4 129 5.3E-37 T 14-10-2018 C2I25_21400 8007750a01c3784adcd792eaa74e548c 226 SMART SM00862 148 223 3.9E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_21400 8007750a01c3784adcd792eaa74e548c 226 Pfam PF00072 Response regulator receiver domain 5 113 1.5E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_18200 98cdcc061fb44c7ef0c6b08c2cf25748 124 SMART SM00345 17 76 4.1E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_18200 98cdcc061fb44c7ef0c6b08c2cf25748 124 SUPERFAMILY SSF46785 6 80 1.27E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_18200 98cdcc061fb44c7ef0c6b08c2cf25748 124 Gene3D G3DSA:1.10.10.10 10 123 1.7E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_18200 98cdcc061fb44c7ef0c6b08c2cf25748 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 4.9E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_12665 8f142abc371e327704716832696c52e9 261 Pfam PF06161 Protein of unknown function (DUF975) 4 257 5.1E-31 T 14-10-2018 IPR010380 Protein of unknown function DUF975 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 Pfam PF00700 Bacterial flagellin C-terminal helical region 186 271 7.2E-24 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 Gene3D G3DSA:1.20.1330.10 43 175 3.0E-53 T 14-10-2018 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 Gene3D G3DSA:1.10.8.410 218 272 4.3E-21 T 14-10-2018 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 PRINTS PR00207 Flagellin signature 35 52 2.5E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 PRINTS PR00207 Flagellin signature 74 93 2.5E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 PRINTS PR00207 Flagellin signature 109 132 2.5E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 1.3E-37 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 SUPERFAMILY SSF64518 1 272 4.71E-81 T 14-10-2018 C2I25_03060 ad28a6edbce996d36bbbfc73d794ee0a 272 Gene3D G3DSA:1.20.58.1830 3 31 3.0E-53 T 14-10-2018 C2I25_21765 ec8a7169429693e8f66839b30dcd5ff3 349 Hamap MF_02040 Iron-sulfur cluster carrier protein. 99 346 31.772 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein C2I25_21765 ec8a7169429693e8f66839b30dcd5ff3 349 SUPERFAMILY SSF117916 1 94 1.67E-20 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I25_21765 ec8a7169429693e8f66839b30dcd5ff3 349 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 113 344 2.8E-82 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 C2I25_21765 ec8a7169429693e8f66839b30dcd5ff3 349 Gene3D G3DSA:3.30.300.130 1 95 1.1E-20 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I25_21765 ec8a7169429693e8f66839b30dcd5ff3 349 Pfam PF01883 Iron-sulfur cluster assembly protein 5 72 4.7E-18 T 14-10-2018 IPR002744 MIP18 family-like C2I25_21765 ec8a7169429693e8f66839b30dcd5ff3 349 ProSitePatterns PS01215 Mrp family signature. 215 231 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 C2I25_21765 ec8a7169429693e8f66839b30dcd5ff3 349 Gene3D G3DSA:3.40.50.300 108 332 3.8E-61 T 14-10-2018 C2I25_21765 ec8a7169429693e8f66839b30dcd5ff3 349 SUPERFAMILY SSF52540 112 346 1.46E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08260 fe68d2b16d642838801a4f98465d0f02 173 Gene3D G3DSA:3.40.430.10 1 173 2.7E-47 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I25_08260 fe68d2b16d642838801a4f98465d0f02 173 SUPERFAMILY SSF53597 2 172 1.44E-37 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I25_08260 fe68d2b16d642838801a4f98465d0f02 173 Pfam PF01872 RibD C-terminal domain 4 164 2.2E-21 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 C2I25_03600 715b365f36cd1c94dd456f7490ff35b9 184 PIRSF PIRSF021290 1 179 3.8E-75 T 14-10-2018 IPR010697 Protein of unknown function DUF1273 C2I25_03600 715b365f36cd1c94dd456f7490ff35b9 184 Gene3D G3DSA:3.40.50.450 1 180 7.1E-70 T 14-10-2018 C2I25_03600 715b365f36cd1c94dd456f7490ff35b9 184 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 1.7E-70 T 14-10-2018 IPR010697 Protein of unknown function DUF1273 C2I25_03600 715b365f36cd1c94dd456f7490ff35b9 184 Hamap MF_01575 UPF0398 protein . 1 177 36.207 T 14-10-2018 IPR010697 Protein of unknown function DUF1273 C2I25_03600 715b365f36cd1c94dd456f7490ff35b9 184 SUPERFAMILY SSF102405 1 177 1.74E-63 T 14-10-2018 C2I25_17405 d34ff358e986536d9c720b7715a6c11d 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 1.1E-115 T 14-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_17405 d34ff358e986536d9c720b7715a6c11d 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 46.526 T 14-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_17405 d34ff358e986536d9c720b7715a6c11d 231 SUPERFAMILY SSF53167 2 230 2.09E-71 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I25_17405 d34ff358e986536d9c720b7715a6c11d 231 Pfam PF01048 Phosphorylase superfamily 2 227 3.6E-53 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I25_17405 d34ff358e986536d9c720b7715a6c11d 231 Gene3D G3DSA:3.40.50.1580 1 231 2.9E-74 T 14-10-2018 C2I25_10065 d55a4e9d501faf08b3bf2db64543ce28 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 140 2.7E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_10065 d55a4e9d501faf08b3bf2db64543ce28 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 172 185 2.7E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_10065 d55a4e9d501faf08b3bf2db64543ce28 319 Pfam PF12146 Serine aminopeptidase, S33 102 186 1.1E-14 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 C2I25_10065 d55a4e9d501faf08b3bf2db64543ce28 319 SUPERFAMILY SSF53474 69 316 6.62E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_10065 d55a4e9d501faf08b3bf2db64543ce28 319 Gene3D G3DSA:3.40.50.1820 70 317 1.3E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_09345 cdcacb4a25695162122f51ef86974747 410 Gene3D G3DSA:1.20.1250.20 205 401 1.2E-18 T 14-10-2018 C2I25_09345 cdcacb4a25695162122f51ef86974747 410 Pfam PF05977 Transmembrane secretion effector 5 401 2.2E-26 T 14-10-2018 IPR010290 Transmembrane secretion effector C2I25_09345 cdcacb4a25695162122f51ef86974747 410 SUPERFAMILY SSF103473 6 394 6.8E-51 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_09345 cdcacb4a25695162122f51ef86974747 410 Gene3D G3DSA:1.20.1250.20 3 195 9.1E-21 T 14-10-2018 C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 SMART SM00393 126 205 5.8E-24 T 14-10-2018 IPR001374 R3H domain GO:0003676 C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Gene3D G3DSA:3.30.1370.50 141 205 3.6E-26 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Pfam PF13083 KH domain 64 128 1.8E-17 T 14-10-2018 C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 SMART SM01245 5 57 4.1E-22 T 14-10-2018 IPR032782 Jag, N-terminal C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 SUPERFAMILY SSF82708 149 204 4.45E-12 T 14-10-2018 IPR036867 R3H domain superfamily GO:0003676 C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Gene3D G3DSA:3.30.30.80 1 57 1.2E-18 T 14-10-2018 IPR038247 Jag, N-terminal domain superfamily C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Pfam PF01424 R3H domain 145 203 9.8E-18 T 14-10-2018 IPR001374 R3H domain GO:0003676 C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Gene3D G3DSA:3.30.300.20 59 140 1.9E-25 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta C2I25_11665 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Pfam PF14804 Jag N-terminus 7 55 3.2E-19 T 14-10-2018 IPR032782 Jag, N-terminal C2I25_28065 28978e1599e0388e2afd0d1abda6c255 428 Pfam PF07690 Major Facilitator Superfamily 25 368 7.7E-20 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_28065 28978e1599e0388e2afd0d1abda6c255 428 SUPERFAMILY SSF103473 17 419 8.28E-34 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_28065 28978e1599e0388e2afd0d1abda6c255 428 Gene3D G3DSA:1.20.1250.20 10 412 5.7E-31 T 14-10-2018 C2I25_26890 74b90f308c2cdc7c504dabeb3e33fd58 147 Pfam PF05995 Cysteine dioxygenase type I 47 146 3.0E-11 T 14-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 C2I25_26890 74b90f308c2cdc7c504dabeb3e33fd58 147 SUPERFAMILY SSF51182 3 146 4.23E-23 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_26890 74b90f308c2cdc7c504dabeb3e33fd58 147 Gene3D G3DSA:2.60.120.10 1 147 2.8E-39 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_18160 8bfeb760066b2020e532762aa38b03fa 264 ProDom PD123329 YQHG BH2818 1 257 5.0E-152 T 14-10-2018 IPR024562 Uncharacterised protein family YqhG C2I25_18160 8bfeb760066b2020e532762aa38b03fa 264 Pfam PF11079 Bacterial protein YqhG of unknown function 1 257 6.6E-127 T 14-10-2018 IPR024562 Uncharacterised protein family YqhG C2I25_20685 f4e522f497b1e0b04d461f112514a9ba 927 SUPERFAMILY SSF48452 46 168 2.61E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_20685 f4e522f497b1e0b04d461f112514a9ba 927 Gene3D G3DSA:1.25.40.10 13 178 7.5E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_20685 f4e522f497b1e0b04d461f112514a9ba 927 SUPERFAMILY SSF52540 369 610 1.5E-22 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20685 f4e522f497b1e0b04d461f112514a9ba 927 Pfam PF00350 Dynamin family 380 516 1.6E-10 T 14-10-2018 IPR022812 Dynamin superfamily C2I25_20685 f4e522f497b1e0b04d461f112514a9ba 927 Gene3D G3DSA:3.40.50.300 380 607 1.5E-24 T 14-10-2018 C2I25_15730 5a5ff035210b73ca8a5bc1968ae86d6c 73 SMART SM00420 11 56 8.0E-4 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_15730 5a5ff035210b73ca8a5bc1968ae86d6c 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 50 8.6E-11 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_15730 5a5ff035210b73ca8a5bc1968ae86d6c 73 SUPERFAMILY SSF46785 10 58 5.17E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_15730 5a5ff035210b73ca8a5bc1968ae86d6c 73 Gene3D G3DSA:1.10.10.10 10 71 1.5E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19005 dd60d4664112931fee77889cf7de30da 296 Pfam PF00589 Phage integrase family 110 282 2.3E-56 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_19005 dd60d4664112931fee77889cf7de30da 296 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 296 62.878 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 C2I25_19005 dd60d4664112931fee77889cf7de30da 296 Gene3D G3DSA:1.10.150.130 2 98 3.9E-23 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I25_19005 dd60d4664112931fee77889cf7de30da 296 Gene3D G3DSA:1.10.443.10 110 290 3.1E-70 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_19005 dd60d4664112931fee77889cf7de30da 296 SUPERFAMILY SSF56349 2 288 1.8E-63 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_19005 dd60d4664112931fee77889cf7de30da 296 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 6 296 5.0E-103 T 14-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 C2I25_19005 dd60d4664112931fee77889cf7de30da 296 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 296 3.2E-126 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 C2I25_19005 dd60d4664112931fee77889cf7de30da 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 296 59.125 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD C2I25_19005 dd60d4664112931fee77889cf7de30da 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 88 2.1E-21 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I25_01745 dd446b631f30465a5286af2a8dd1416a 229 Pfam PF00072 Response regulator receiver domain 4 114 8.1E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_01745 dd446b631f30465a5286af2a8dd1416a 229 SMART SM00448 2 113 1.3E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_01745 dd446b631f30465a5286af2a8dd1416a 229 SUPERFAMILY SSF52172 2 169 3.08E-40 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_01745 dd446b631f30465a5286af2a8dd1416a 229 SMART SM00862 148 224 6.3E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_01745 dd446b631f30465a5286af2a8dd1416a 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 1.2E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_01745 dd446b631f30465a5286af2a8dd1416a 229 Gene3D G3DSA:3.40.50.2300 1 126 1.7E-35 T 14-10-2018 C2I25_01745 dd446b631f30465a5286af2a8dd1416a 229 Gene3D G3DSA:1.10.10.10 127 228 2.6E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.4E-45 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 Gene3D G3DSA:3.30.470.130 1 445 6.0E-192 T 14-10-2018 C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 SUPERFAMILY SSF52440 1 113 3.17E-48 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 SUPERFAMILY SSF56059 83 352 1.22E-65 T 14-10-2018 C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 Pfam PF02785 Biotin carboxylase C-terminal domain 336 439 2.9E-34 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 SMART SM00878 336 439 2.0E-51 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 SUPERFAMILY SSF51246 331 440 2.09E-37 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_27130 716f58380d7863ba6dd1e85627ab8714 445 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 2.2E-75 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I25_24525 f4ae2c41ece199e52a17ff06334bcec4 244 SMART SM00850 148 241 1.0E-19 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_24525 f4ae2c41ece199e52a17ff06334bcec4 244 Gene3D G3DSA:3.40.50.2300 1 138 1.1E-38 T 14-10-2018 C2I25_24525 f4ae2c41ece199e52a17ff06334bcec4 244 Pfam PF04397 LytTr DNA-binding domain 150 240 2.6E-21 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_24525 f4ae2c41ece199e52a17ff06334bcec4 244 SUPERFAMILY SSF52172 1 178 6.4E-6 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_24525 f4ae2c41ece199e52a17ff06334bcec4 244 Gene3D G3DSA:2.40.50.1020 139 244 5.4E-29 T 14-10-2018 C2I25_24525 f4ae2c41ece199e52a17ff06334bcec4 244 Pfam PF00072 Response regulator receiver domain 3 113 1.2E-8 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_14425 6fe40f615a985dc9fbac233d5c340066 219 Pfam PF00005 ABC transporter 18 156 3.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_14425 6fe40f615a985dc9fbac233d5c340066 219 Gene3D G3DSA:3.40.50.300 8 219 1.2E-58 T 14-10-2018 C2I25_14425 6fe40f615a985dc9fbac233d5c340066 219 SUPERFAMILY SSF52540 17 208 1.21E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_14425 6fe40f615a985dc9fbac233d5c340066 219 SMART SM00382 22 205 1.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_14425 6fe40f615a985dc9fbac233d5c340066 219 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_06305 7a83df9199bd44b33366bf901a9ec8dd 283 Pfam PF00561 alpha/beta hydrolase fold 58 157 4.9E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_06305 7a83df9199bd44b33366bf901a9ec8dd 283 Pfam PF00561 alpha/beta hydrolase fold 193 266 6.0E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_06305 7a83df9199bd44b33366bf901a9ec8dd 283 Gene3D G3DSA:3.40.50.1820 25 283 1.6E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_06305 7a83df9199bd44b33366bf901a9ec8dd 283 SUPERFAMILY SSF53474 31 279 4.19E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_06305 7a83df9199bd44b33366bf901a9ec8dd 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 128 141 2.0E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_06305 7a83df9199bd44b33366bf901a9ec8dd 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 98 2.0E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_06305 7a83df9199bd44b33366bf901a9ec8dd 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 142 155 2.0E-9 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_23860 058a7ed5ed04d13d333ec925abcd136b 380 Gene3D G3DSA:1.20.1250.20 2 374 1.2E-40 T 14-10-2018 C2I25_23860 058a7ed5ed04d13d333ec925abcd136b 380 Pfam PF07690 Major Facilitator Superfamily 8 317 2.7E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_23860 058a7ed5ed04d13d333ec925abcd136b 380 SUPERFAMILY SSF103473 4 376 3.14E-47 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_12315 d1c1af3f3fe1f21aef1c70053d144582 275 Gene3D G3DSA:2.30.140.10 1 52 1.2E-24 T 14-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I25_12315 d1c1af3f3fe1f21aef1c70053d144582 275 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 275 42.126 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I25_12315 d1c1af3f3fe1f21aef1c70053d144582 275 SUPERFAMILY SSF53335 3 274 1.83E-88 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_12315 d1c1af3f3fe1f21aef1c70053d144582 275 Gene3D G3DSA:3.40.50.150 53 274 1.8E-77 T 14-10-2018 C2I25_12315 d1c1af3f3fe1f21aef1c70053d144582 275 TIGRFAM TIGR00417 speE: spermidine synthase 4 269 3.6E-120 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I25_12315 d1c1af3f3fe1f21aef1c70053d144582 275 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 14-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I25_12315 d1c1af3f3fe1f21aef1c70053d144582 275 Pfam PF01564 Spermine/spermidine synthase domain 58 236 5.1E-68 T 14-10-2018 C2I25_12315 d1c1af3f3fe1f21aef1c70053d144582 275 Pfam PF17284 Spermidine synthase tetramerisation domain 3 55 7.2E-20 T 14-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I25_24445 b543a989813adfc5cadc69e0a1906e5b 584 Pfam PF13382 Adenine deaminase C-terminal domain 410 571 5.4E-38 T 14-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 C2I25_24445 b543a989813adfc5cadc69e0a1906e5b 584 Gene3D G3DSA:3.20.20.140 82 325 3.4E-79 T 14-10-2018 C2I25_24445 b543a989813adfc5cadc69e0a1906e5b 584 SUPERFAMILY SSF51338 23 369 5.11E-15 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_24445 b543a989813adfc5cadc69e0a1906e5b 584 SUPERFAMILY SSF51556 83 327 1.16E-9 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_24445 b543a989813adfc5cadc69e0a1906e5b 584 Pfam PF01979 Amidohydrolase family 78 362 6.9E-18 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I25_24445 b543a989813adfc5cadc69e0a1906e5b 584 Gene3D G3DSA:2.30.40.10 22 362 3.4E-79 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_03705 588919fe410a4c55b3450b23bf0672e7 129 Pfam PF13473 Cupredoxin-like domain 14 128 4.8E-23 T 14-10-2018 IPR028096 EfeO-type cupredoxin-like domain C2I25_03705 588919fe410a4c55b3450b23bf0672e7 129 Gene3D G3DSA:2.60.40.420 30 129 8.5E-39 T 14-10-2018 IPR008972 Cupredoxin C2I25_03705 588919fe410a4c55b3450b23bf0672e7 129 SUPERFAMILY SSF49503 40 128 5.03E-15 T 14-10-2018 IPR008972 Cupredoxin C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.8E-37 T 14-10-2018 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.8E-37 T 14-10-2018 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 1.8E-37 T 14-10-2018 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 1.8E-37 T 14-10-2018 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.8E-37 T 14-10-2018 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 10 308 8.1E-121 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 44 59 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 237 258 2.0E-70 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 297 6.2E-50 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 SUPERFAMILY SSF51905 6 305 2.11E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 Gene3D G3DSA:3.50.50.60 120 243 1.6E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 138 158 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 C2I25_13435 b0dbddcb2349b50fed39a60fef8f1ffe 321 Gene3D G3DSA:3.50.50.60 11 304 1.6E-115 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_11500 8e95aa4b73d1a784f4f776083ff607c9 89 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 84 9.3E-21 T 14-10-2018 IPR010001 SigmaK-factor processing regulatory BofA C2I25_11500 8e95aa4b73d1a784f4f776083ff607c9 89 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 2.5E-28 T 14-10-2018 IPR010001 SigmaK-factor processing regulatory BofA C2I25_02385 0e52c9e86f01cc03ae003f32f0dab889 238 Pfam PF04474 Protein of unknown function (DUF554) 4 226 9.8E-74 T 14-10-2018 IPR007563 Protein of unknown function DUF554 C2I25_22815 f660e2ef2dfb1123d37ea7d54f656887 157 SUPERFAMILY SSF55331 76 145 8.18E-13 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_22815 f660e2ef2dfb1123d37ea7d54f656887 157 Gene3D G3DSA:3.30.429.10 2 70 1.0E-20 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_22815 f660e2ef2dfb1123d37ea7d54f656887 157 Gene3D G3DSA:3.30.429.10 90 156 8.2E-16 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_22815 f660e2ef2dfb1123d37ea7d54f656887 157 Pfam PF01361 Tautomerase enzyme 12 59 2.1E-8 T 14-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 C2I25_22815 f660e2ef2dfb1123d37ea7d54f656887 157 Pfam PF01361 Tautomerase enzyme 90 143 2.0E-6 T 14-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 C2I25_22815 f660e2ef2dfb1123d37ea7d54f656887 157 SUPERFAMILY SSF55331 2 70 2.26E-13 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_02295 d2a7d8c9da89e0b9cf44ee92cac1c5ea 314 SUPERFAMILY SSF51735 1 130 2.29E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_02295 d2a7d8c9da89e0b9cf44ee92cac1c5ea 314 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 177 300 2.4E-24 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain C2I25_02295 d2a7d8c9da89e0b9cf44ee92cac1c5ea 314 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 6.2E-37 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain C2I25_02295 d2a7d8c9da89e0b9cf44ee92cac1c5ea 314 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 302 2.5E-72 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 C2I25_02295 d2a7d8c9da89e0b9cf44ee92cac1c5ea 314 Gene3D G3DSA:1.10.1040.10 177 301 1.3E-29 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_02295 d2a7d8c9da89e0b9cf44ee92cac1c5ea 314 Gene3D G3DSA:3.40.50.720 1 172 2.4E-52 T 14-10-2018 C2I25_02295 d2a7d8c9da89e0b9cf44ee92cac1c5ea 314 SUPERFAMILY SSF48179 177 301 1.5E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_14625 0c048575cdc9aa844f103f4a66ec76d4 330 SUPERFAMILY SSF52283 12 142 8.08E-31 T 14-10-2018 C2I25_14625 0c048575cdc9aa844f103f4a66ec76d4 330 SUPERFAMILY SSF51735 113 298 6.13E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_14625 0c048575cdc9aa844f103f4a66ec76d4 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 328 7.4E-29 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 C2I25_14625 0c048575cdc9aa844f103f4a66ec76d4 330 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 158 186 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 C2I25_14625 0c048575cdc9aa844f103f4a66ec76d4 330 Gene3D G3DSA:3.40.50.720 14 324 1.3E-113 T 14-10-2018 C2I25_14625 0c048575cdc9aa844f103f4a66ec76d4 330 Gene3D G3DSA:3.40.50.720 107 297 1.3E-113 T 14-10-2018 C2I25_14625 0c048575cdc9aa844f103f4a66ec76d4 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 297 2.6E-64 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I25_26795 8b23fb8abca32ba9d75a0ec8292259c1 413 SUPERFAMILY SSF53474 31 387 7.24E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_26795 8b23fb8abca32ba9d75a0ec8292259c1 413 Gene3D G3DSA:3.40.50.1820 24 413 4.6E-150 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_06800 aa12370c4ffe8e4b1aea0756bbe7ab00 347 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 75 335 2.1E-22 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 C2I25_06800 aa12370c4ffe8e4b1aea0756bbe7ab00 347 Gene3D G3DSA:3.40.190.10 150 276 4.5E-59 T 14-10-2018 C2I25_06800 aa12370c4ffe8e4b1aea0756bbe7ab00 347 Gene3D G3DSA:3.40.190.150 59 335 4.5E-59 T 14-10-2018 C2I25_06800 aa12370c4ffe8e4b1aea0756bbe7ab00 347 SUPERFAMILY SSF53850 138 314 8.87E-9 T 14-10-2018 C2I25_06800 aa12370c4ffe8e4b1aea0756bbe7ab00 347 PIRSF PIRSF017082 19 345 2.6E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 C2I25_11685 a668902e04efb0d375dd78555605d3a5 290 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 34 212 1.4E-59 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 C2I25_11685 a668902e04efb0d375dd78555605d3a5 290 Gene3D G3DSA:1.10.10.2830 114 228 2.9E-35 T 14-10-2018 C2I25_11685 a668902e04efb0d375dd78555605d3a5 290 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 35 288 3.9E-115 T 14-10-2018 IPR023705 Nucleoid occlusion protein C2I25_11685 a668902e04efb0d375dd78555605d3a5 290 SUPERFAMILY SSF110849 36 173 8.89E-35 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily C2I25_11685 a668902e04efb0d375dd78555605d3a5 290 SMART SM00470 37 127 6.7E-34 T 14-10-2018 IPR003115 ParB/Sulfiredoxin C2I25_11685 a668902e04efb0d375dd78555605d3a5 290 Gene3D G3DSA:3.90.1530.30 50 113 5.7E-25 T 14-10-2018 C2I25_11685 a668902e04efb0d375dd78555605d3a5 290 Pfam PF02195 ParB-like nuclease domain 38 126 1.1E-26 T 14-10-2018 IPR003115 ParB/Sulfiredoxin C2I25_11685 a668902e04efb0d375dd78555605d3a5 290 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 288 39.198 T 14-10-2018 IPR023705 Nucleoid occlusion protein C2I25_18375 143e400c96f9b0f6c31cc3cc9465f809 210 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 199 3.8E-34 T 14-10-2018 IPR014245 Sporulation stage III, protein AF C2I25_18375 143e400c96f9b0f6c31cc3cc9465f809 210 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 2 111 1.7E-36 T 14-10-2018 IPR014245 Sporulation stage III, protein AF C2I25_00905 4d70079d83bf105962ef47633fc43209 378 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 77 120 4.4E-8 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I25_00905 4d70079d83bf105962ef47633fc43209 378 Pfam PF00589 Phage integrase family 173 357 1.3E-29 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_00905 4d70079d83bf105962ef47633fc43209 378 Pfam PF14657 Arm DNA-binding domain 11 56 2.9E-16 T 14-10-2018 IPR028259 AP2-like integrase, N-terminal domain C2I25_00905 4d70079d83bf105962ef47633fc43209 378 SUPERFAMILY SSF56349 65 365 1.5E-70 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_00905 4d70079d83bf105962ef47633fc43209 378 Gene3D G3DSA:1.10.150.130 64 159 1.4E-18 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I25_00905 4d70079d83bf105962ef47633fc43209 378 Gene3D G3DSA:1.10.443.10 160 373 7.9E-57 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_04745 6a986f22109171e9c12d36b7a3cb25f2 93 Pfam PF09388 Spo0E like sporulation regulatory protein 13 54 1.6E-14 T 14-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I25_04745 6a986f22109171e9c12d36b7a3cb25f2 93 SUPERFAMILY SSF140500 9 62 3.66E-15 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_04745 6a986f22109171e9c12d36b7a3cb25f2 93 Gene3D G3DSA:1.20.58.990 8 65 3.6E-13 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_14385 7579bfb548cd1ea22393ca126a75a2b9 156 SMART SM00860 16 147 1.7E-10 T 14-10-2018 IPR018958 Knr4/Smi1-like domain C2I25_14385 7579bfb548cd1ea22393ca126a75a2b9 156 SUPERFAMILY SSF160631 9 150 4.19E-28 T 14-10-2018 C2I25_14385 7579bfb548cd1ea22393ca126a75a2b9 156 Pfam PF14568 SMI1-KNR4 cell-wall 19 145 1.8E-28 T 14-10-2018 C2I25_14385 7579bfb548cd1ea22393ca126a75a2b9 156 Gene3D G3DSA:3.40.1580.10 5 156 2.5E-31 T 14-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I25_12355 4cf173abef49531db23173e667e27c93 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 167 4.3E-31 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_12355 4cf173abef49531db23173e667e27c93 175 Gene3D G3DSA:1.10.10.10 106 170 1.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_12355 4cf173abef49531db23173e667e27c93 175 Gene3D G3DSA:1.10.1740.10 1 77 3.7E-18 T 14-10-2018 C2I25_12355 4cf173abef49531db23173e667e27c93 175 Pfam PF08281 Sigma-70, region 4 111 163 3.3E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_12355 4cf173abef49531db23173e667e27c93 175 SUPERFAMILY SSF88659 100 168 1.16E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_12355 4cf173abef49531db23173e667e27c93 175 SUPERFAMILY SSF88946 4 86 1.33E-19 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_12355 4cf173abef49531db23173e667e27c93 175 Pfam PF04542 Sigma-70 region 2 8 75 1.0E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_24960 440c9901e1015d4e5a672e697765f154 251 SUPERFAMILY SSF52540 3 234 1.77E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24960 440c9901e1015d4e5a672e697765f154 251 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_24960 440c9901e1015d4e5a672e697765f154 251 Gene3D G3DSA:3.40.50.300 2 242 3.3E-63 T 14-10-2018 C2I25_24960 440c9901e1015d4e5a672e697765f154 251 Pfam PF00005 ABC transporter 22 158 2.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_24960 440c9901e1015d4e5a672e697765f154 251 SMART SM00382 31 208 4.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_12485 d958e9af61891ee10d51269cc76fef99 122 SMART SM00448 3 114 1.7E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12485 d958e9af61891ee10d51269cc76fef99 122 SUPERFAMILY SSF52172 4 118 1.99E-36 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_12485 d958e9af61891ee10d51269cc76fef99 122 Pfam PF00072 Response regulator receiver domain 5 115 3.8E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12485 d958e9af61891ee10d51269cc76fef99 122 Gene3D G3DSA:3.40.50.2300 1 121 2.3E-41 T 14-10-2018 C2I25_00070 630371f941636ff35e6b150316fa75cf 185 Gene3D G3DSA:3.40.50.620 58 165 3.3E-6 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_00070 630371f941636ff35e6b150316fa75cf 185 Pfam PF02698 DUF218 domain 38 175 9.3E-29 T 14-10-2018 IPR003848 Domain of unknown function DUF218 C2I25_06510 b7e0fb0b7ae16a80f7881cd691dc85fa 296 Pfam PF12844 Helix-turn-helix domain 9 67 7.6E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_06510 b7e0fb0b7ae16a80f7881cd691dc85fa 296 SMART SM00530 9 63 4.0E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_06510 b7e0fb0b7ae16a80f7881cd691dc85fa 296 Gene3D G3DSA:1.25.40.10 1 296 5.2E-83 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_06510 b7e0fb0b7ae16a80f7881cd691dc85fa 296 SUPERFAMILY SSF47413 5 65 2.04E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_06510 b7e0fb0b7ae16a80f7881cd691dc85fa 296 SUPERFAMILY SSF48452 116 257 4.55E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 PRINTS PR01469 Bacterial carbamate kinase signature 31 50 5.0E-6 T 14-10-2018 C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 PRINTS PR01469 Bacterial carbamate kinase signature 155 170 5.0E-6 T 14-10-2018 C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 PRINTS PR01469 Bacterial carbamate kinase signature 204 219 5.0E-6 T 14-10-2018 C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 Pfam PF00696 Amino acid kinase family 5 231 1.3E-44 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 229 5.7E-73 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 Hamap MF_00082 Acetylglutamate kinase [argB]. 2 247 42.49 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 Gene3D G3DSA:3.40.1160.10 2 253 1.7E-71 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 PIRSF PIRSF000728 1 251 2.6E-87 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I25_18770 7e5ce38e20e0249af225d69f57727cfe 255 SUPERFAMILY SSF53633 2 250 7.2E-64 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_09405 2339ea4825b580278d2f0f1c704bd1aa 106 Gene3D G3DSA:3.30.70.930 1 106 2.3E-49 T 14-10-2018 IPR029756 MTH1187/YkoF-like C2I25_09405 2339ea4825b580278d2f0f1c704bd1aa 106 Pfam PF01910 Thiamine-binding protein 7 96 9.9E-30 T 14-10-2018 IPR002767 Thiamine-binding protein C2I25_09405 2339ea4825b580278d2f0f1c704bd1aa 106 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 7 93 3.1E-16 T 14-10-2018 IPR002767 Thiamine-binding protein C2I25_09405 2339ea4825b580278d2f0f1c704bd1aa 106 SUPERFAMILY SSF89957 3 104 1.83E-31 T 14-10-2018 IPR029756 MTH1187/YkoF-like C2I25_18630 fc5d983a041028e0b197ec7c5ca98333 154 PRINTS PR00502 NUDIX hydrolase family signature 44 58 2.2E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_18630 fc5d983a041028e0b197ec7c5ca98333 154 PRINTS PR00502 NUDIX hydrolase family signature 58 73 2.2E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_18630 fc5d983a041028e0b197ec7c5ca98333 154 Gene3D G3DSA:3.90.79.10 1 152 1.4E-37 T 14-10-2018 C2I25_18630 fc5d983a041028e0b197ec7c5ca98333 154 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_18630 fc5d983a041028e0b197ec7c5ca98333 154 SUPERFAMILY SSF55811 7 147 1.15E-31 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_18630 fc5d983a041028e0b197ec7c5ca98333 154 Pfam PF00293 NUDIX domain 20 143 5.4E-23 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_15785 e80de77aafbf27fedd356fcfb6d2d555 104 SUPERFAMILY SSF52833 4 102 1.37E-26 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_15785 e80de77aafbf27fedd356fcfb6d2d555 104 Gene3D G3DSA:3.40.30.10 1 102 1.2E-23 T 14-10-2018 C2I25_15785 e80de77aafbf27fedd356fcfb6d2d555 104 Pfam PF00085 Thioredoxin 11 101 6.0E-17 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I25_08765 9f697d53285a442e52442b7ab13b8e2b 162 Gene3D G3DSA:3.40.1280.10 1 162 9.1E-75 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I25_08765 9f697d53285a442e52442b7ab13b8e2b 162 PIRSF PIRSF029256 2 157 2.0E-68 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 C2I25_08765 9f697d53285a442e52442b7ab13b8e2b 162 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 2.6E-67 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 C2I25_08765 9f697d53285a442e52442b7ab13b8e2b 162 Pfam PF00588 SpoU rRNA Methylase family 3 145 3.8E-36 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 C2I25_08765 9f697d53285a442e52442b7ab13b8e2b 162 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.875 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 C2I25_08765 9f697d53285a442e52442b7ab13b8e2b 162 SUPERFAMILY SSF75217 3 155 5.23E-46 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 SMART SM00642 33 421 3.0E-72 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 SUPERFAMILY SSF51445 34 413 1.24E-105 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 Gene3D G3DSA:2.60.40.1180 427 513 1.3E-35 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 PIRSF PIRSF001021 9 513 2.4E-235 T 14-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 Gene3D G3DSA:3.20.20.80 34 398 3.9E-166 T 14-10-2018 C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 Pfam PF00128 Alpha amylase, catalytic domain 64 402 3.4E-24 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 Gene3D G3DSA:2.40.30.140 132 235 3.9E-166 T 14-10-2018 C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 Pfam PF09154 Domain of unknown function (DUF1939) 465 510 1.9E-7 T 14-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 C2I25_22285 09b69ac5b2c96ce364b4557839928957 513 SUPERFAMILY SSF51011 424 513 1.58E-35 T 14-10-2018 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 Pfam PF01197 Ribosomal protein L31 1 79 1.2E-28 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 9.8E-20 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 PRINTS PR01249 Ribosomal protein L31 signature 45 60 2.6E-19 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.6E-19 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 PRINTS PR01249 Ribosomal protein L31 signature 60 78 2.6E-19 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 27.75 T 14-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 Gene3D G3DSA:2.30.170.50 1 81 8.1E-26 T 14-10-2018 C2I25_12515 534bb178ebbf231ad42537171e69a916 81 SUPERFAMILY SSF143800 1 80 7.06E-24 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_24815 53219c45452442f0e028d914e0ec6be3 366 Gene3D G3DSA:3.40.50.720 1 179 1.9E-50 T 14-10-2018 C2I25_24815 53219c45452442f0e028d914e0ec6be3 366 SUPERFAMILY SSF55021 289 347 3.78E-7 T 14-10-2018 C2I25_24815 53219c45452442f0e028d914e0ec6be3 366 Pfam PF02153 Prephenate dehydrogenase 17 273 1.5E-77 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 C2I25_24815 53219c45452442f0e028d914e0ec6be3 366 SUPERFAMILY SSF51735 4 170 7.01E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_24815 53219c45452442f0e028d914e0ec6be3 366 SUPERFAMILY SSF48179 175 283 7.25E-32 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_24815 53219c45452442f0e028d914e0ec6be3 366 Gene3D G3DSA:1.10.3660.10 181 295 3.2E-33 T 14-10-2018 C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 Pfam PF00270 DEAD/DEAH box helicase 7 171 1.0E-50 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 130 138 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 1 505 44.935 T 14-10-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 Gene3D G3DSA:3.40.50.300 1 188 9.3E-71 T 14-10-2018 C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 SMART SM00490 235 316 1.3E-34 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 Pfam PF00271 Helicase conserved C-terminal domain 208 316 5.2E-29 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 Gene3D G3DSA:3.40.50.300 192 414 5.7E-55 T 14-10-2018 C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 SUPERFAMILY SSF52540 52 337 2.28E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10290 6d6b5d231a0e1c2bcabe7762d62900a8 510 SMART SM00487 2 199 6.1E-66 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_15440 dfa7a0e02bd1c5af57e247589215ae3a 380 SUPERFAMILY SSF53756 2 372 1.96E-80 T 14-10-2018 C2I25_15440 dfa7a0e02bd1c5af57e247589215ae3a 380 Gene3D G3DSA:3.40.50.2000 1 195 1.9E-28 T 14-10-2018 C2I25_15440 dfa7a0e02bd1c5af57e247589215ae3a 380 Gene3D G3DSA:3.40.50.2000 196 354 2.4E-39 T 14-10-2018 C2I25_15440 dfa7a0e02bd1c5af57e247589215ae3a 380 Pfam PF13439 Glycosyltransferase Family 4 14 177 4.9E-23 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I25_15440 dfa7a0e02bd1c5af57e247589215ae3a 380 Pfam PF00534 Glycosyl transferases group 1 189 347 1.9E-32 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 C2I25_18605 8fb8cc959fbe0c6fb85202b8dbb74f83 327 Gene3D G3DSA:3.40.50.970 1 192 6.4E-92 T 14-10-2018 C2I25_18605 8fb8cc959fbe0c6fb85202b8dbb74f83 327 SUPERFAMILY SSF52922 188 325 1.19E-40 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_18605 8fb8cc959fbe0c6fb85202b8dbb74f83 327 Gene3D G3DSA:3.40.50.920 193 327 3.2E-43 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_18605 8fb8cc959fbe0c6fb85202b8dbb74f83 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 6.5E-52 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_18605 8fb8cc959fbe0c6fb85202b8dbb74f83 327 SMART SM00861 4 179 1.7E-69 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_18605 8fb8cc959fbe0c6fb85202b8dbb74f83 327 SUPERFAMILY SSF52518 2 204 7.5E-74 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_18605 8fb8cc959fbe0c6fb85202b8dbb74f83 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 1.7E-41 T 14-10-2018 IPR033248 Transketolase, C-terminal domain C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 Gene3D G3DSA:3.30.230.10 226 404 9.3E-74 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 Pfam PF01751 Toprim domain 425 536 2.5E-19 T 14-10-2018 IPR006171 TOPRIM domain C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 SUPERFAMILY SSF55874 11 219 4.32E-73 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 40 55 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 118 132 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 75 88 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 426 440 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 274 287 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 530 542 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 492 508 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 572 588 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 510 527 1.9E-71 T 14-10-2018 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 SMART SM00433 40 633 0.0 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 179 5.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 Pfam PF00204 DNA gyrase B 227 396 2.0E-64 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 SUPERFAMILY SSF54211 227 397 6.07E-63 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 Gene3D G3DSA:3.40.50.670 405 640 2.7E-110 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 11 21 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 609 625 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 593 605 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 318 334 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 366 380 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 380 400 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 476 485 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 226 248 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.0E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 Gene3D G3DSA:3.30.565.10 7 225 4.7E-93 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 640 101.599 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 SMART SM00387 36 180 4.7E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 629 7.8E-30 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 640 0.0 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I25_11625 bb74aea3ef89623741ee15a51c5a746c 640 SUPERFAMILY SSF56719 400 632 1.2E-91 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I25_01510 cf3b3946b22794378f366a5d7c4a7a16 489 Pfam PF07282 Putative transposase DNA-binding domain 380 459 1.1E-6 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal C2I25_01510 cf3b3946b22794378f366a5d7c4a7a16 489 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 328 406 3.7E-18 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal C2I25_01510 cf3b3946b22794378f366a5d7c4a7a16 489 Pfam PF01385 Probable transposase 247 359 4.9E-19 T 14-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 SUPERFAMILY SSF56634 3 483 7.2E-211 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 Pfam PF00199 Catalase 8 387 7.4E-191 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 SMART SM01060 8 391 1.3E-278 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 334 342 - T 14-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 Pfam PF06628 Catalase-related immune-responsive 414 475 2.5E-18 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 Gene3D G3DSA:2.40.180.10 1 487 3.6E-228 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 PRINTS PR00067 Catalase signature 124 142 1.9E-76 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 PRINTS PR00067 Catalase signature 289 316 1.9E-76 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 PRINTS PR00067 Catalase signature 321 347 1.9E-76 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 PRINTS PR00067 Catalase signature 84 102 1.9E-76 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 PRINTS PR00067 Catalase signature 21 44 1.9E-76 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 PRINTS PR00067 Catalase signature 105 122 1.9E-76 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 PIRSF PIRSF038928 1 481 6.6E-201 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_05630 f849cd2df3bcc85b75e4f4c7e8dca7be 488 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 PRINTS PR00421 Thioredoxin family signature 28 37 7.7E-7 T 14-10-2018 C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 PRINTS PR00421 Thioredoxin family signature 20 28 7.7E-7 T 14-10-2018 C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 PRINTS PR00421 Thioredoxin family signature 68 79 7.7E-7 T 14-10-2018 C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 Pfam PF00085 Thioredoxin 4 103 3.8E-30 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 SUPERFAMILY SSF52833 3 103 1.44E-35 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 103 3.6E-37 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 Gene3D G3DSA:3.40.30.10 1 104 1.2E-34 T 14-10-2018 C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 PIRSF PIRSF000077 1 104 2.9E-40 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 C2I25_16720 c49277f17c7fb3b66ac2967b6765f737 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 C2I25_14560 65edea61f93d8fd9e51261b1a668c9ff 247 Gene3D G3DSA:3.90.640.20 152 247 2.2E-26 T 14-10-2018 IPR037126 PdaC/RsiV-like superfamily C2I25_14560 65edea61f93d8fd9e51261b1a668c9ff 247 Pfam PF11738 Protein of unknown function (DUF3298) 154 228 4.4E-18 T 14-10-2018 IPR021729 Domain of unknown function DUF3298 C2I25_14560 65edea61f93d8fd9e51261b1a668c9ff 247 Pfam PF13739 Domain of unknown function (DUF4163) 40 135 1.7E-23 T 14-10-2018 IPR025303 Deacetylase PdaC C2I25_14560 65edea61f93d8fd9e51261b1a668c9ff 247 Gene3D G3DSA:3.30.565.40 31 150 1.4E-27 T 14-10-2018 C2I25_23030 d2626e4140e506fad4d8c62cc18eceed 397 Pfam PF07690 Major Facilitator Superfamily 12 302 2.7E-23 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_23030 d2626e4140e506fad4d8c62cc18eceed 397 Gene3D G3DSA:1.20.1250.20 202 384 6.3E-18 T 14-10-2018 C2I25_23030 d2626e4140e506fad4d8c62cc18eceed 397 SUPERFAMILY SSF103473 9 381 6.28E-50 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_23030 d2626e4140e506fad4d8c62cc18eceed 397 Gene3D G3DSA:1.20.1250.20 2 201 3.3E-23 T 14-10-2018 C2I25_01645 58484dd27fc030f36c1d5421ea9b0df3 386 SMART SM00460 179 235 1.1E-7 T 14-10-2018 IPR002931 Transglutaminase-like C2I25_01645 58484dd27fc030f36c1d5421ea9b0df3 386 Gene3D G3DSA:3.10.620.30 96 251 3.2E-21 T 14-10-2018 C2I25_01645 58484dd27fc030f36c1d5421ea9b0df3 386 SUPERFAMILY SSF54001 135 270 6.11E-24 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_01645 58484dd27fc030f36c1d5421ea9b0df3 386 Pfam PF01841 Transglutaminase-like superfamily 139 232 4.6E-14 T 14-10-2018 IPR002931 Transglutaminase-like C2I25_11325 e869a53a17650dbac309029c58bc00ba 91 PIRSF PIRSF038881 1 88 4.7E-36 T 14-10-2018 IPR025490 RNA-binding protein, HP1423 type C2I25_11325 e869a53a17650dbac309029c58bc00ba 91 Gene3D G3DSA:3.10.290.10 1 89 2.4E-24 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_11325 e869a53a17650dbac309029c58bc00ba 91 SUPERFAMILY SSF55174 1 77 1.96E-20 T 14-10-2018 C2I25_11325 e869a53a17650dbac309029c58bc00ba 91 Pfam PF01479 S4 domain 1 46 1.3E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_11325 e869a53a17650dbac309029c58bc00ba 91 SMART SM00363 1 64 4.0E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_04335 038fad7d53f545d398603fc6a2600ef7 55 Pfam PF13217 Protein of unknown function (DUF4025) 4 48 4.1E-16 T 14-10-2018 IPR025100 Protein of unknown function DUF4025 C2I25_08530 f38692c43e62ebd3373436bedc5eac9e 623 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 13 350 7.4E-83 T 14-10-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain C2I25_08530 f38692c43e62ebd3373436bedc5eac9e 623 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 366 581 9.9E-28 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I25_08530 f38692c43e62ebd3373436bedc5eac9e 623 Gene3D G3DSA:3.20.20.190 352 590 2.5E-58 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_08530 f38692c43e62ebd3373436bedc5eac9e 623 SUPERFAMILY SSF51695 360 586 8.89E-64 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 Gene3D G3DSA:1.20.890.100 170 224 9.7E-21 T 14-10-2018 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 Gene3D G3DSA:1.20.58.1950 226 277 3.8E-24 T 14-10-2018 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 Pfam PF03123 CAT RNA binding domain 6 60 8.4E-24 T 14-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 SUPERFAMILY SSF50151 6 57 3.53E-17 T 14-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 ProSitePatterns PS00654 PRD domain signature. 102 114 - T 14-10-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 Gene3D G3DSA:2.30.24.10 1 70 7.8E-26 T 14-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 SMART SM01061 5 63 1.0E-27 T 14-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 SUPERFAMILY SSF63520 181 277 1.18E-24 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 Gene3D G3DSA:1.10.1790.10 71 169 1.8E-32 T 14-10-2018 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 SUPERFAMILY SSF63520 60 171 8.63E-32 T 14-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 Pfam PF00874 PRD domain 185 275 2.1E-21 T 14-10-2018 IPR011608 PRD domain GO:0006355 C2I25_19215 3b24c08d92c765a4a882eaba1eb0d6e1 282 Pfam PF00874 PRD domain 80 166 2.2E-25 T 14-10-2018 IPR011608 PRD domain GO:0006355 C2I25_00535 885b0f1e80171bc50d227a1c140f9ecb 84 Pfam PF14201 Domain of unknown function (DUF4318) 14 84 6.2E-24 T 14-10-2018 IPR025467 Protein of unknown function DUF4318 C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 89 168 1.0E-4 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 Gene3D G3DSA:2.60.120.10 63 235 1.9E-162 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 Pfam PF00190 Cupin 67 192 2.6E-19 T 14-10-2018 IPR006045 Cupin 1 GO:0045735 C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 Pfam PF00190 Cupin 235 367 1.1E-22 T 14-10-2018 IPR006045 Cupin 1 GO:0045735 C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 SMART SM00835 57 198 1.7E-14 T 14-10-2018 IPR006045 Cupin 1 GO:0045735 C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 SMART SM00835 234 375 2.6E-28 T 14-10-2018 IPR006045 Cupin 1 GO:0045735 C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 21 385 3.5E-175 T 14-10-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 SUPERFAMILY SSF51182 26 384 1.16E-100 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_06290 1349fb039e76f40bff59e8f05ef83402 398 Gene3D G3DSA:2.60.120.10 14 379 1.9E-162 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_14540 6644b97dad66b000d5ede56b53ef50fe 201 Gene3D G3DSA:3.40.1700.10 70 201 1.2E-53 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I25_14540 6644b97dad66b000d5ede56b53ef50fe 201 Hamap MF_00838 Diadenylate cyclase [dacB]. 14 201 36.797 T 14-10-2018 IPR034693 Diadenylate cyclase CdaS GO:0004016|GO:0006171 C2I25_14540 6644b97dad66b000d5ede56b53ef50fe 201 Pfam PF10372 Bacterial membrane-spanning protein N-terminus 1 69 2.4E-26 T 14-10-2018 IPR019457 Uncharacterised domain YojJ, N-terminal C2I25_14540 6644b97dad66b000d5ede56b53ef50fe 201 Gene3D G3DSA:1.10.287.770 1 69 2.3E-41 T 14-10-2018 C2I25_14540 6644b97dad66b000d5ede56b53ef50fe 201 PIRSF PIRSF004793 1 201 1.7E-64 T 14-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 C2I25_14540 6644b97dad66b000d5ede56b53ef50fe 201 SUPERFAMILY SSF143597 32 198 4.05E-53 T 14-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I25_14540 6644b97dad66b000d5ede56b53ef50fe 201 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 78 194 7.0E-41 T 14-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal C2I25_18795 fad7de67769b192eeb1fa56cb09e3563 106 Pfam PF09951 Protein of unknown function (DUF2185) 11 87 1.1E-20 T 14-10-2018 IPR018689 Domain of unknown function DUF2185 C2I25_18075 6c0f26ac0e3d8f5e4f567b8038757152 464 Gene3D G3DSA:1.10.3860.10 20 461 8.4E-107 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_18075 6c0f26ac0e3d8f5e4f567b8038757152 464 SUPERFAMILY SSF118215 31 443 1.96E-94 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_18075 6c0f26ac0e3d8f5e4f567b8038757152 464 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 1.1E-17 T 14-10-2018 C2I25_18075 6c0f26ac0e3d8f5e4f567b8038757152 464 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 1.1E-17 T 14-10-2018 C2I25_18075 6c0f26ac0e3d8f5e4f567b8038757152 464 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 1.1E-17 T 14-10-2018 C2I25_18075 6c0f26ac0e3d8f5e4f567b8038757152 464 PRINTS PR00173 Glutamate-aspartate symporter signature 233 252 1.1E-17 T 14-10-2018 C2I25_18075 6c0f26ac0e3d8f5e4f567b8038757152 464 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 1.1E-17 T 14-10-2018 C2I25_18075 6c0f26ac0e3d8f5e4f567b8038757152 464 Pfam PF00375 Sodium:dicarboxylate symporter family 32 443 2.9E-100 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 9.2E-58 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 9.2E-58 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 9.2E-58 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 9.2E-58 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 9.2E-58 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 SUPERFAMILY SSF53067 143 325 3.44E-47 T 14-10-2018 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 327 5.1E-136 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 Gene3D G3DSA:3.30.420.40 6 319 1.2E-125 T 14-10-2018 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 Gene3D G3DSA:3.30.420.40 146 309 1.2E-125 T 14-10-2018 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 Pfam PF06723 MreB/Mbl protein 4 327 7.1E-148 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 Gene3D G3DSA:3.90.640.10 178 251 1.2E-125 T 14-10-2018 C2I25_12785 ca8d2b094c938a665db0459a285aa7be 333 SUPERFAMILY SSF53067 3 140 9.79E-39 T 14-10-2018 C2I25_07440 2b4b5df893696939eadc3c3a2605f7f5 119 Pfam PF00581 Rhodanese-like domain 33 118 7.6E-16 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_07440 2b4b5df893696939eadc3c3a2605f7f5 119 SMART SM00450 30 119 3.0E-15 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_07440 2b4b5df893696939eadc3c3a2605f7f5 119 SUPERFAMILY SSF52821 9 118 6.16E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_07440 2b4b5df893696939eadc3c3a2605f7f5 119 Gene3D G3DSA:3.40.250.10 25 119 5.4E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_19225 48008f36b23ef60c873996270d2019b1 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 80 6.6E-31 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_19225 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 12 28 6.6E-24 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_19225 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 37 52 6.6E-24 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_19225 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 52 69 6.6E-24 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_19225 48008f36b23ef60c873996270d2019b1 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 12 19 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site C2I25_19225 48008f36b23ef60c873996270d2019b1 87 Gene3D G3DSA:3.30.1340.10 1 87 5.9E-35 T 14-10-2018 IPR035895 HPr-like superfamily C2I25_19225 48008f36b23ef60c873996270d2019b1 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 38 53 - T 14-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site C2I25_19225 48008f36b23ef60c873996270d2019b1 87 SUPERFAMILY SSF55594 3 82 5.89E-27 T 14-10-2018 IPR035895 HPr-like superfamily C2I25_19225 48008f36b23ef60c873996270d2019b1 87 Pfam PF00381 PTS HPr component phosphorylation site 2 81 2.2E-28 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_02790 4dd0b2348a522e9b84ca4076d499640c 294 Pfam PF09323 Domain of unknown function (DUF1980) 12 199 1.0E-46 T 14-10-2018 IPR015402 Protein of unknown function DUF1980 C2I25_02790 4dd0b2348a522e9b84ca4076d499640c 294 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 30 287 1.3E-67 T 14-10-2018 IPR015402 Protein of unknown function DUF1980 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 5.9E-119 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 Pfam PF02881 SRP54-type protein, helical bundle domain 34 99 9.3E-15 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 SMART SM00962 120 321 1.4E-123 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 SMART SM00963 22 103 3.4E-25 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 SMART SM00382 119 297 3.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 Gene3D G3DSA:1.20.120.140 20 318 6.5E-117 T 14-10-2018 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 5.4E-82 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 SUPERFAMILY SSF52540 117 319 1.13E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 Gene3D G3DSA:3.40.50.300 112 309 6.5E-117 T 14-10-2018 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 65.112 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 C2I25_20275 c3b8a3a4e64fddeb478639b4364081d4 329 SUPERFAMILY SSF47364 18 96 3.01E-22 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 C2I25_19945 05a6ba51d54ecc8a6c5c667f521a0a73 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 1.9E-47 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19945 05a6ba51d54ecc8a6c5c667f521a0a73 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 35.011 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19945 05a6ba51d54ecc8a6c5c667f521a0a73 364 Gene3D G3DSA:3.40.50.2000 1 176 1.1E-61 T 14-10-2018 C2I25_19945 05a6ba51d54ecc8a6c5c667f521a0a73 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 353 8.4E-43 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 C2I25_19945 05a6ba51d54ecc8a6c5c667f521a0a73 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 357 3.9E-101 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19945 05a6ba51d54ecc8a6c5c667f521a0a73 364 Gene3D G3DSA:3.40.50.2000 177 346 2.3E-50 T 14-10-2018 C2I25_19945 05a6ba51d54ecc8a6c5c667f521a0a73 364 SUPERFAMILY SSF53756 2 362 2.92E-110 T 14-10-2018 C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 SUPERFAMILY SSF53335 697 824 1.33E-19 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 Pfam PF00535 Glycosyl transferase family 2 325 460 4.9E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 Pfam PF00535 Glycosyl transferase family 2 19 149 5.6E-23 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 Pfam PF08241 Methyltransferase domain 722 770 4.6E-12 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 Gene3D G3DSA:3.40.50.150 681 847 5.3E-23 T 14-10-2018 C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 Gene3D G3DSA:3.90.550.10 255 577 1.9E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 Gene3D G3DSA:3.90.550.10 1 254 8.7E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 SUPERFAMILY SSF53448 16 246 3.94E-46 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_01895 1e3d29fd1e32dc091b2165ac7760aa94 853 SUPERFAMILY SSF53448 322 550 1.5E-45 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_02830 a66a3d08be24a3006c4ef160637d4169 299 SUPERFAMILY SSF160240 213 285 2.35E-9 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I25_02830 a66a3d08be24a3006c4ef160637d4169 299 Gene3D G3DSA:1.20.1510.10 12 209 6.5E-46 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I25_02830 a66a3d08be24a3006c4ef160637d4169 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 287 2.1E-92 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I25_02830 a66a3d08be24a3006c4ef160637d4169 299 Pfam PF01545 Cation efflux family 16 209 1.1E-51 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I25_02830 a66a3d08be24a3006c4ef160637d4169 299 SUPERFAMILY SSF161111 9 210 1.05E-58 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I25_19685 85a99539be93a97416a199a15de4b6cd 89 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 86 1.5E-37 T 14-10-2018 IPR007920 Protein of unknown function UPF0223 C2I25_19685 85a99539be93a97416a199a15de4b6cd 89 Gene3D G3DSA:1.10.220.80 12 89 9.8E-30 T 14-10-2018 IPR023324 BH2638-like superfamily C2I25_19685 85a99539be93a97416a199a15de4b6cd 89 SUPERFAMILY SSF158504 4 86 1.96E-34 T 14-10-2018 IPR023324 BH2638-like superfamily C2I25_19685 85a99539be93a97416a199a15de4b6cd 89 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 86 2.0E-41 T 14-10-2018 IPR007920 Protein of unknown function UPF0223 C2I25_19685 85a99539be93a97416a199a15de4b6cd 89 Hamap MF_01041 UPF0223 protein . 1 88 26.992 T 14-10-2018 IPR007920 Protein of unknown function UPF0223 C2I25_19685 85a99539be93a97416a199a15de4b6cd 89 PIRSF PIRSF037260 1 89 1.2E-39 T 14-10-2018 IPR007920 Protein of unknown function UPF0223 C2I25_16170 8b466fa29c014acfd3d45058b447393c 152 Pfam PF00582 Universal stress protein family 5 144 9.1E-37 T 14-10-2018 IPR006016 UspA C2I25_16170 8b466fa29c014acfd3d45058b447393c 152 Gene3D G3DSA:3.40.50.620 7 144 2.6E-42 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_16170 8b466fa29c014acfd3d45058b447393c 152 SUPERFAMILY SSF52402 5 144 2.09E-35 T 14-10-2018 C2I25_16170 8b466fa29c014acfd3d45058b447393c 152 PRINTS PR01438 Universal stress protein signature 104 116 7.9E-19 T 14-10-2018 IPR006015 Universal stress protein A C2I25_16170 8b466fa29c014acfd3d45058b447393c 152 PRINTS PR01438 Universal stress protein signature 122 144 7.9E-19 T 14-10-2018 IPR006015 Universal stress protein A C2I25_16170 8b466fa29c014acfd3d45058b447393c 152 PRINTS PR01438 Universal stress protein signature 5 23 7.9E-19 T 14-10-2018 IPR006015 Universal stress protein A C2I25_16170 8b466fa29c014acfd3d45058b447393c 152 PIRSF PIRSF006276 1 147 2.1E-22 T 14-10-2018 IPR006015 Universal stress protein A C2I25_17640 176348c52b379cd699f9ea5af6b19f2e 199 Pfam PF10531 SLBB domain 65 113 1.9E-10 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_17640 176348c52b379cd699f9ea5af6b19f2e 199 Gene3D G3DSA:1.10.150.280 126 198 5.0E-22 T 14-10-2018 C2I25_17640 176348c52b379cd699f9ea5af6b19f2e 199 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 134 198 5.6E-25 T 14-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain C2I25_17640 176348c52b379cd699f9ea5af6b19f2e 199 SMART SM00278 146 165 0.097 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_17640 176348c52b379cd699f9ea5af6b19f2e 199 SMART SM00278 176 195 3.6 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_17640 176348c52b379cd699f9ea5af6b19f2e 199 Pfam PF12836 Helix-hairpin-helix motif 136 196 5.3E-22 T 14-10-2018 C2I25_17640 176348c52b379cd699f9ea5af6b19f2e 199 SUPERFAMILY SSF47781 124 198 2.33E-27 T 14-10-2018 IPR010994 RuvA domain 2-like C2I25_27965 ea2016c51d82e4a1417148f686765c9d 312 Gene3D G3DSA:2.160.20.80 162 303 1.1E-18 T 14-10-2018 C2I25_27965 ea2016c51d82e4a1417148f686765c9d 312 SUPERFAMILY SSF55729 7 155 5.75E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27965 ea2016c51d82e4a1417148f686765c9d 312 Pfam PF13599 Pentapeptide repeats (9 copies) 175 251 2.5E-17 T 14-10-2018 IPR001646 Pentapeptide repeat C2I25_27965 ea2016c51d82e4a1417148f686765c9d 312 Pfam PF13673 Acetyltransferase (GNAT) domain 60 153 8.9E-12 T 14-10-2018 IPR000182 GNAT domain C2I25_27965 ea2016c51d82e4a1417148f686765c9d 312 Gene3D G3DSA:3.40.630.30 1 161 5.6E-23 T 14-10-2018 C2I25_27965 ea2016c51d82e4a1417148f686765c9d 312 SUPERFAMILY SSF141571 172 301 1.15E-21 T 14-10-2018 C2I25_02500 4f7c7d48bf2d98ef4ef13b3b9763c996 403 Pfam PF07690 Major Facilitator Superfamily 23 361 1.8E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_02500 4f7c7d48bf2d98ef4ef13b3b9763c996 403 Gene3D G3DSA:1.20.1250.20 221 401 5.9E-25 T 14-10-2018 C2I25_02500 4f7c7d48bf2d98ef4ef13b3b9763c996 403 SUPERFAMILY SSF103473 11 395 1.96E-56 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_02500 4f7c7d48bf2d98ef4ef13b3b9763c996 403 Gene3D G3DSA:1.20.1250.20 4 195 2.6E-20 T 14-10-2018 C2I25_23240 fca21922948ef605c23b3b0fec1f14fd 284 Pfam PF00561 alpha/beta hydrolase fold 24 267 4.5E-22 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_23240 fca21922948ef605c23b3b0fec1f14fd 284 SUPERFAMILY SSF53474 3 280 1.62E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_23240 fca21922948ef605c23b3b0fec1f14fd 284 Gene3D G3DSA:3.40.50.1820 1 282 4.6E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_23240 fca21922948ef605c23b3b0fec1f14fd 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 9.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_23240 fca21922948ef605c23b3b0fec1f14fd 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 9.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_23240 fca21922948ef605c23b3b0fec1f14fd 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 227 241 9.1E-8 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_05490 eb769846d14959ac835cf2e5323042cd 309 Gene3D G3DSA:1.10.3720.10 84 299 8.0E-19 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05490 eb769846d14959ac835cf2e5323042cd 309 SUPERFAMILY SSF161098 89 291 9.81E-16 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05490 eb769846d14959ac835cf2e5323042cd 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 7.2E-36 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_04625 53128b024c1e5fa027083a9dc7fda814 300 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_04625 53128b024c1e5fa027083a9dc7fda814 300 Pfam PF00005 ABC transporter 22 163 3.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_04625 53128b024c1e5fa027083a9dc7fda814 300 SMART SM00382 30 212 9.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_04625 53128b024c1e5fa027083a9dc7fda814 300 Gene3D G3DSA:3.40.50.300 3 241 4.3E-63 T 14-10-2018 C2I25_04625 53128b024c1e5fa027083a9dc7fda814 300 SUPERFAMILY SSF52540 2 233 1.78E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.056 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 Gene3D G3DSA:3.90.1170.10 1 144 2.9E-55 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.0E-62 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 6.9E-52 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.8E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.8E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.8E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.8E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10935 e4cf20b16964edc7537e0e4e3f2c0454 144 SUPERFAMILY SSF54686 1 136 3.66E-58 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 Gene3D G3DSA:3.20.20.120 118 346 2.6E-126 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 Pfam PF13378 Enolase C-terminal domain-like 145 343 1.9E-40 T 14-10-2018 IPR029065 Enolase C-terminal domain-like C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 9 125 6.9E-13 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 43.554 T 14-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 SUPERFAMILY SSF51604 114 361 1.02E-58 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 9 332 5.9E-122 T 14-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 Gene3D G3DSA:3.30.390.10 9 357 2.6E-126 T 14-10-2018 IPR029017 Enolase-like, N-terminal C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 SUPERFAMILY SSF54826 2 126 2.89E-32 T 14-10-2018 C2I25_14915 f680082ae3f0cb48fb7581f98df5719e 368 SMART SM00922 142 234 5.2E-20 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal C2I25_24950 241283faa5ad52372fc42dbb356bd152 196 SUPERFAMILY SSF46689 2 76 1.8E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_24950 241283faa5ad52372fc42dbb356bd152 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 6.4E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24950 241283faa5ad52372fc42dbb356bd152 196 Gene3D G3DSA:1.10.357.10 1 192 1.0E-26 T 14-10-2018 C2I25_24950 241283faa5ad52372fc42dbb356bd152 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.3E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24950 241283faa5ad52372fc42dbb356bd152 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.3E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_12830 8a3d8c9a65bf77279ed7667d7e429df6 371 Gene3D G3DSA:3.40.50.20 1 116 5.1E-23 T 14-10-2018 C2I25_12830 8a3d8c9a65bf77279ed7667d7e429df6 371 Pfam PF13535 ATP-grasp domain 135 274 3.6E-14 T 14-10-2018 C2I25_12830 8a3d8c9a65bf77279ed7667d7e429df6 371 SUPERFAMILY SSF56059 89 309 3.35E-28 T 14-10-2018 C2I25_12830 8a3d8c9a65bf77279ed7667d7e429df6 371 Gene3D G3DSA:3.30.1490.20 120 181 1.3E-6 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I25_12830 8a3d8c9a65bf77279ed7667d7e429df6 371 Gene3D G3DSA:3.30.470.20 182 371 2.2E-29 T 14-10-2018 C2I25_12830 8a3d8c9a65bf77279ed7667d7e429df6 371 SUPERFAMILY SSF52440 3 69 6.91E-6 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_11875 80ed459634fa5901a16f2ae037380e7b 221 Pfam PF00089 Trypsin 23 111 1.9E-4 T 14-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 C2I25_11875 80ed459634fa5901a16f2ae037380e7b 221 Gene3D G3DSA:2.40.10.10 109 208 6.5E-9 T 14-10-2018 C2I25_11875 80ed459634fa5901a16f2ae037380e7b 221 SUPERFAMILY SSF50494 23 171 7.74E-12 T 14-10-2018 IPR009003 Peptidase S1, PA clan C2I25_11875 80ed459634fa5901a16f2ae037380e7b 221 Gene3D G3DSA:2.40.10.10 11 108 1.4E-9 T 14-10-2018 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 Gene3D G3DSA:1.25.40.10 23 210 3.9E-52 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF13414 TPR repeat 49 82 3.9E-8 T 14-10-2018 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF13176 Tetratricopeptide repeat 108 138 0.024 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF13181 Tetratricopeptide repeat 141 170 0.0035 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 35 68 0.0021 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 137 170 0.039 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 69 102 0.059 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 103 136 0.62 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 1 34 15.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 171 204 2.4E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 SUPERFAMILY SSF48452 8 212 8.72E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF07719 Tetratricopeptide repeat 8 34 1.4E-5 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 C2I25_17300 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF00515 Tetratricopeptide repeat 171 204 5.0E-8 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 C2I25_02995 120bade2b451efc7c12f5f1c7f988fc1 432 Gene3D G3DSA:3.20.20.30 3 428 5.4E-102 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_02995 120bade2b451efc7c12f5f1c7f988fc1 432 Pfam PF00296 Luciferase-like monooxygenase 26 376 3.4E-54 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I25_02995 120bade2b451efc7c12f5f1c7f988fc1 432 PIRSF PIRSF000337 7 430 3.8E-116 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I25_02995 120bade2b451efc7c12f5f1c7f988fc1 432 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 16 420 9.9E-104 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I25_02995 120bade2b451efc7c12f5f1c7f988fc1 432 SUPERFAMILY SSF51679 26 424 5.23E-93 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_10915 58eb0371898030313e2cb82b106fae0f 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 14-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10915 58eb0371898030313e2cb82b106fae0f 103 SMART SM00739 2 29 4.8E-4 T 14-10-2018 IPR005824 KOW C2I25_10915 58eb0371898030313e2cb82b106fae0f 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 4.2E-42 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10915 58eb0371898030313e2cb82b106fae0f 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 4.9E-33 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10915 58eb0371898030313e2cb82b106fae0f 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.712 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10915 58eb0371898030313e2cb82b106fae0f 103 Pfam PF00467 KOW motif 5 36 2.8E-6 T 14-10-2018 IPR005824 KOW C2I25_10915 58eb0371898030313e2cb82b106fae0f 103 SUPERFAMILY SSF50104 1 99 1.96E-40 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I25_10915 58eb0371898030313e2cb82b106fae0f 103 Gene3D G3DSA:2.30.30.30 1 100 4.5E-44 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 C2I25_14640 ea8aa25ec7d391f9b5d13fbeecd124fc 114 PRINTS PR00681 Ribosomal protein S1 signature 60 78 6.8E-12 T 14-10-2018 C2I25_14640 ea8aa25ec7d391f9b5d13fbeecd124fc 114 PRINTS PR00681 Ribosomal protein S1 signature 21 40 6.8E-12 T 14-10-2018 C2I25_14640 ea8aa25ec7d391f9b5d13fbeecd124fc 114 Gene3D G3DSA:2.40.50.140 2 85 4.8E-31 T 14-10-2018 C2I25_14640 ea8aa25ec7d391f9b5d13fbeecd124fc 114 Pfam PF00575 S1 RNA binding domain 7 77 2.9E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 C2I25_14640 ea8aa25ec7d391f9b5d13fbeecd124fc 114 SMART SM00316 6 77 3.4E-25 T 14-10-2018 IPR022967 RNA-binding domain, S1 C2I25_14640 ea8aa25ec7d391f9b5d13fbeecd124fc 114 SUPERFAMILY SSF50249 4 89 6.99E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_19420 3d73d0d1a8db144e6c6da6def1212399 433 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 215 419 1.1E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_19420 3d73d0d1a8db144e6c6da6def1212399 433 SUPERFAMILY SSF160964 86 185 5.49E-10 T 14-10-2018 C2I25_19420 3d73d0d1a8db144e6c6da6def1212399 433 Gene3D G3DSA:1.10.3720.10 176 433 1.8E-67 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_19420 3d73d0d1a8db144e6c6da6def1212399 433 SUPERFAMILY SSF161098 180 417 7.46E-57 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07955 c031d07415ca51dc122d3cff3f3ea4c8 65 Pfam PF11755 Protein of unknown function (DUF3311) 6 62 7.5E-17 T 14-10-2018 IPR021741 Protein of unknown function DUF3311 C2I25_03050 2527e72287c1ece1d4a88aba8b3e392c 74 SUPERFAMILY SSF101801 3 72 1.31E-13 T 14-10-2018 IPR036429 SpoA-like superfamily C2I25_03050 2527e72287c1ece1d4a88aba8b3e392c 74 Gene3D G3DSA:2.30.330.10 1 74 1.4E-12 T 14-10-2018 IPR036429 SpoA-like superfamily C2I25_03050 2527e72287c1ece1d4a88aba8b3e392c 74 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 5 72 3.3E-10 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) C2I25_03050 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 49 64 1.7E-5 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03050 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 3 19 1.7E-5 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03050 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 20 36 1.7E-5 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_16455 7e6a8969768d1de0b90aae5c1dfdf620 361 Gene3D G3DSA:2.40.30.40 77 164 2.5E-136 T 14-10-2018 IPR023367 Peptidase M42, domain 2 C2I25_16455 7e6a8969768d1de0b90aae5c1dfdf620 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 7.7E-118 T 14-10-2018 IPR008007 Peptidase M42 C2I25_16455 7e6a8969768d1de0b90aae5c1dfdf620 361 PIRSF PIRSF001123 4 361 3.7E-150 T 14-10-2018 IPR008007 Peptidase M42 C2I25_16455 7e6a8969768d1de0b90aae5c1dfdf620 361 SUPERFAMILY SSF53187 8 355 2.62E-71 T 14-10-2018 C2I25_16455 7e6a8969768d1de0b90aae5c1dfdf620 361 SUPERFAMILY SSF101821 73 182 2.9E-34 T 14-10-2018 C2I25_16455 7e6a8969768d1de0b90aae5c1dfdf620 361 Gene3D G3DSA:3.40.630.10 12 345 2.5E-136 T 14-10-2018 C2I25_18180 5a86b5396c000323ed67e3729a64ab9f 491 Gene3D G3DSA:3.40.640.10 86 317 4.0E-57 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_18180 5a86b5396c000323ed67e3729a64ab9f 491 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 60.644 T 14-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 C2I25_18180 5a86b5396c000323ed67e3729a64ab9f 491 Gene3D G3DSA:3.90.1150.10 338 470 3.1E-47 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_18180 5a86b5396c000323ed67e3729a64ab9f 491 Pfam PF02347 Glycine cleavage system P-protein 51 300 1.9E-9 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 C2I25_18180 5a86b5396c000323ed67e3729a64ab9f 491 SUPERFAMILY SSF53383 12 483 5.25E-112 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_25180 7d562e20ddcf640229ffcc5252639b2c 235 Pfam PF04519 Polymer-forming cytoskeletal 58 135 3.4E-6 T 14-10-2018 IPR007607 Bactofilin A/B C2I25_20395 99b3090eed953da9d2547be3d81c25e8 258 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 256 2.0E-86 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 C2I25_20395 99b3090eed953da9d2547be3d81c25e8 258 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 257 40.689 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 C2I25_20395 99b3090eed953da9d2547be3d81c25e8 258 Gene3D G3DSA:3.40.1180.10 12 258 1.6E-101 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 C2I25_20395 99b3090eed953da9d2547be3d81c25e8 258 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 256 1.7E-87 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 C2I25_20395 99b3090eed953da9d2547be3d81c25e8 258 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 C2I25_20395 99b3090eed953da9d2547be3d81c25e8 258 SUPERFAMILY SSF64005 25 251 2.49E-90 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 Gene3D G3DSA:3.40.50.970 367 573 2.1E-71 T 14-10-2018 C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 SUPERFAMILY SSF52467 202 367 4.48E-62 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 SUPERFAMILY SSF52518 11 196 3.83E-64 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 545 4.2E-52 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 SUPERFAMILY SSF52518 375 568 1.12E-69 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 Gene3D G3DSA:3.40.50.1220 202 365 5.9E-62 T 14-10-2018 C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 18 568 4.7E-256 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 18 184 1.9E-59 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 Gene3D G3DSA:3.40.50.970 11 192 1.7E-74 T 14-10-2018 C2I25_02420 8d208ffc9d16a99e0aca26ac0910393c 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 208 342 6.2E-44 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I25_11240 68d15c0552b52ef619cda553b3349027 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 25 40 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_11240 68d15c0552b52ef619cda553b3349027 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 25 274 2.7E-101 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 C2I25_11240 68d15c0552b52ef619cda553b3349027 280 Gene3D G3DSA:3.20.20.20 4 280 4.0E-120 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_11240 68d15c0552b52ef619cda553b3349027 280 Pfam PF00809 Pterin binding enzyme 26 259 3.2E-88 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_11240 68d15c0552b52ef619cda553b3349027 280 SUPERFAMILY SSF51717 12 276 2.22E-103 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_11240 68d15c0552b52ef619cda553b3349027 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 59 72 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I25_12440 4750cee24a825c2b66be6dc8a2dcc8c7 703 SUPERFAMILY SSF46548 252 400 1.46E-20 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I25_12440 4750cee24a825c2b66be6dc8a2dcc8c7 703 Pfam PF02754 Cysteine-rich domain 460 543 1.0E-6 T 14-10-2018 IPR004017 Cysteine-rich domain C2I25_12440 4750cee24a825c2b66be6dc8a2dcc8c7 703 Pfam PF02754 Cysteine-rich domain 582 669 1.2E-17 T 14-10-2018 IPR004017 Cysteine-rich domain C2I25_12440 4750cee24a825c2b66be6dc8a2dcc8c7 703 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 372 383 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I25_12440 4750cee24a825c2b66be6dc8a2dcc8c7 703 SUPERFAMILY SSF103501 13 238 3.01E-15 T 14-10-2018 IPR036197 NarG-like superfamily C2I25_12440 4750cee24a825c2b66be6dc8a2dcc8c7 703 Pfam PF13183 4Fe-4S dicluster domain 274 384 2.6E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_27900 db7fdaa0bb3a51ded079e59ea3a8c95f 257 Gene3D G3DSA:3.30.1240.10 81 177 9.5E-62 T 14-10-2018 C2I25_27900 db7fdaa0bb3a51ded079e59ea3a8c95f 257 SUPERFAMILY SSF56784 1 249 2.71E-61 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_27900 db7fdaa0bb3a51ded079e59ea3a8c95f 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 221 3.5E-22 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_27900 db7fdaa0bb3a51ded079e59ea3a8c95f 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 248 1.9E-51 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_27900 db7fdaa0bb3a51ded079e59ea3a8c95f 257 Gene3D G3DSA:3.40.50.1000 3 249 9.5E-62 T 14-10-2018 IPR023214 HAD superfamily C2I25_27900 db7fdaa0bb3a51ded079e59ea3a8c95f 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 248 2.6E-64 T 14-10-2018 C2I25_03270 96ccca139f1b8cd4ab5055f2360621d7 406 Gene3D G3DSA:1.20.1250.20 2 390 1.1E-32 T 14-10-2018 C2I25_03270 96ccca139f1b8cd4ab5055f2360621d7 406 Pfam PF07690 Major Facilitator Superfamily 8 351 1.5E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_03270 96ccca139f1b8cd4ab5055f2360621d7 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 130 151 5.3E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03270 96ccca139f1b8cd4ab5055f2360621d7 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 292 315 5.3E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03270 96ccca139f1b8cd4ab5055f2360621d7 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 6 28 5.3E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03270 96ccca139f1b8cd4ab5055f2360621d7 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 69 87 5.3E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03270 96ccca139f1b8cd4ab5055f2360621d7 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 157 174 5.3E-8 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03270 96ccca139f1b8cd4ab5055f2360621d7 406 SUPERFAMILY SSF103473 3 391 5.23E-42 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_10260 4b682577e07d0a759bac6defa2d4c5e6 95 Gene3D G3DSA:1.10.1220.10 1 95 8.6E-33 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 C2I25_27675 bca6f56d2f47550ebe9f5fadcb920b78 228 SMART SM00849 19 222 1.1E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_27675 bca6f56d2f47550ebe9f5fadcb920b78 228 Gene3D G3DSA:3.60.15.10 17 228 2.3E-36 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_27675 bca6f56d2f47550ebe9f5fadcb920b78 228 SUPERFAMILY SSF56281 22 227 1.1E-37 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_27675 bca6f56d2f47550ebe9f5fadcb920b78 228 Pfam PF00753 Metallo-beta-lactamase superfamily 26 215 1.5E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_08150 8e66839b3724fe42832de4621edb9c83 215 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I25_08150 8e66839b3724fe42832de4621edb9c83 215 Gene3D G3DSA:3.20.20.70 1 215 5.1E-90 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_08150 8e66839b3724fe42832de4621edb9c83 215 SUPERFAMILY SSF51569 1 212 8.37E-79 T 14-10-2018 C2I25_08150 8e66839b3724fe42832de4621edb9c83 215 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 211 1.3E-55 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I25_08150 8e66839b3724fe42832de4621edb9c83 215 Hamap MF_00494 Probable transaldolase [tal]. 1 214 48.4 T 14-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I25_08150 8e66839b3724fe42832de4621edb9c83 215 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 2.6E-102 T 14-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I25_08150 8e66839b3724fe42832de4621edb9c83 215 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I25_03750 7a5b84a7e08d59c164099a26465e49ac 293 PIRSF PIRSF006483 1 287 4.5E-91 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_03750 7a5b84a7e08d59c164099a26465e49ac 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 225 279 2.1E-22 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_03750 7a5b84a7e08d59c164099a26465e49ac 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 219 2.1E-63 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_03750 7a5b84a7e08d59c164099a26465e49ac 293 Gene3D G3DSA:3.30.70.120 197 272 1.8E-27 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_22000 3e5d0ff53c8e2264b601ec5726a92da0 182 Pfam PF06268 Fascin domain 56 135 7.1E-7 T 14-10-2018 IPR022768 Fascin domain GO:0030674|GO:0051015 C2I25_22000 3e5d0ff53c8e2264b601ec5726a92da0 182 SUPERFAMILY SSF50405 58 180 3.2E-25 T 14-10-2018 IPR008999 Actin-crosslinking C2I25_22000 3e5d0ff53c8e2264b601ec5726a92da0 182 Gene3D G3DSA:2.80.10.50 59 181 3.0E-28 T 14-10-2018 C2I25_05625 bed358b1dbb40c97af1bd6feacf7b376 410 Pfam PF00909 Ammonium Transporter Family 7 403 1.5E-130 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 C2I25_05625 bed358b1dbb40c97af1bd6feacf7b376 410 Gene3D G3DSA:1.10.3430.10 1 410 2.2E-151 T 14-10-2018 IPR029020 Ammonium/urea transporter C2I25_05625 bed358b1dbb40c97af1bd6feacf7b376 410 ProSitePatterns PS01219 Ammonium transporters signature. 160 185 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 C2I25_05625 bed358b1dbb40c97af1bd6feacf7b376 410 TIGRFAM TIGR00836 amt: ammonium transporter 5 403 1.6E-143 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 C2I25_05625 bed358b1dbb40c97af1bd6feacf7b376 410 SUPERFAMILY SSF111352 2 384 4.58E-128 T 14-10-2018 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.8E-23 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 Gene3D G3DSA:3.40.50.720 4 336 2.6E-147 T 14-10-2018 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 Pfam PF01842 ACT domain 351 403 3.9E-8 T 14-10-2018 IPR002912 ACT domain C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 Pfam PF00742 Homoserine dehydrogenase 137 315 2.8E-65 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 SUPERFAMILY SSF55347 137 302 1.24E-52 T 14-10-2018 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 Gene3D G3DSA:3.30.360.10 136 343 2.6E-147 T 14-10-2018 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 PIRSF PIRSF000098 1 429 3.1E-168 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 SUPERFAMILY SSF51735 1 158 1.23E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 SUPERFAMILY SSF55021 348 414 4.58E-10 T 14-10-2018 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 355 397 0.002 T 14-10-2018 C2I25_12150 eb8608d7992e85e0b042ffc5a73ad49c 431 Gene3D G3DSA:3.30.70.260 344 415 2.6E-147 T 14-10-2018 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 345 366 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 458 479 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 275 296 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 336 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 408 427 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 175 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 380 398 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 121 145 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 195 213 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 94 117 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 224 243 1.5E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 502 4.7E-142 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 Gene3D G3DSA:1.20.210.10 31 562 1.3E-198 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 277 331 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 5 645 0.0 T 14-10-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 C2I25_07980 a9ddf31db06c16792b2eb37f32ef7616 647 SUPERFAMILY SSF81442 51 576 2.62E-175 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07575 92e427d86026c1a7a8d3c74d7ddcedcf 253 SUPERFAMILY SSF141523 23 142 7.72E-35 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I25_07575 92e427d86026c1a7a8d3c74d7ddcedcf 253 Pfam PF03734 L,D-transpeptidase catalytic domain 24 142 1.5E-24 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I25_07575 92e427d86026c1a7a8d3c74d7ddcedcf 253 Gene3D G3DSA:2.40.440.10 14 172 2.5E-42 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I25_09205 52c3044094df70e12fe2aac04bbedf54 138 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 5 128 1.1E-18 T 14-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain C2I25_09205 52c3044094df70e12fe2aac04bbedf54 138 SUPERFAMILY SSF50475 3 128 3.37E-29 T 14-10-2018 C2I25_09205 52c3044094df70e12fe2aac04bbedf54 138 Gene3D G3DSA:2.30.110.10 1 138 1.5E-41 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I25_18520 410a2947d0ef820ba15ec128063becd8 102 Gene3D G3DSA:1.10.3230.30 1 100 1.2E-12 T 14-10-2018 C2I25_18520 410a2947d0ef820ba15ec128063becd8 102 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 13 84 8.9E-13 T 14-10-2018 IPR006450 Phage protein of unkonwn function C2I25_18520 410a2947d0ef820ba15ec128063becd8 102 Pfam PF05135 Phage gp6-like head-tail connector protein 7 94 4.2E-20 T 14-10-2018 IPR021146 Phage gp6-like head-tail connector protein C2I25_12530 18de18cb1ec0a7ad0ebeacb087700f57 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 185 191 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 C2I25_12530 18de18cb1ec0a7ad0ebeacb087700f57 283 SUPERFAMILY SSF53335 3 280 8.51E-55 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_12530 18de18cb1ec0a7ad0ebeacb087700f57 283 Pfam PF05175 Methyltransferase small domain 113 191 1.5E-15 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 C2I25_12530 18de18cb1ec0a7ad0ebeacb087700f57 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 280 7.8E-78 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 C2I25_12530 18de18cb1ec0a7ad0ebeacb087700f57 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 278 8.3E-88 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 C2I25_12530 18de18cb1ec0a7ad0ebeacb087700f57 283 Gene3D G3DSA:1.10.8.10 1 83 5.5E-18 T 14-10-2018 C2I25_12530 18de18cb1ec0a7ad0ebeacb087700f57 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 282 43.935 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 C2I25_12530 18de18cb1ec0a7ad0ebeacb087700f57 283 Gene3D G3DSA:3.40.50.150 84 283 5.4E-66 T 14-10-2018 C2I25_14985 bf78aa885660641d7af3332acb94637b 250 SMART SM00382 32 220 1.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_14985 bf78aa885660641d7af3332acb94637b 250 Pfam PF00005 ABC transporter 23 171 3.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_14985 bf78aa885660641d7af3332acb94637b 250 Gene3D G3DSA:3.40.50.300 1 240 2.9E-66 T 14-10-2018 C2I25_14985 bf78aa885660641d7af3332acb94637b 250 SUPERFAMILY SSF52540 4 224 5.97E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05385 53669dc15bb97c0d17750fd1556a4f94 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 133 147 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_05385 53669dc15bb97c0d17750fd1556a4f94 297 Gene3D G3DSA:3.30.2350.10 83 297 8.0E-69 T 14-10-2018 C2I25_05385 53669dc15bb97c0d17750fd1556a4f94 297 Pfam PF00849 RNA pseudouridylate synthase 91 241 1.7E-31 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_05385 53669dc15bb97c0d17750fd1556a4f94 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 39 296 5.9E-77 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_05385 53669dc15bb97c0d17750fd1556a4f94 297 SUPERFAMILY SSF55120 75 295 4.48E-72 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_11225 b3f54ff5258645be62fdabc96c5ccc3f 67 SUPERFAMILY SSF47413 4 65 2.09E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_11225 b3f54ff5258645be62fdabc96c5ccc3f 67 Gene3D G3DSA:1.10.260.40 2 67 1.5E-19 T 14-10-2018 C2I25_11225 b3f54ff5258645be62fdabc96c5ccc3f 67 Pfam PF01381 Helix-turn-helix 10 64 8.2E-18 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_11225 b3f54ff5258645be62fdabc96c5ccc3f 67 SMART SM00530 9 64 2.6E-18 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_19885 8431b572312c978c55455569a8c344b7 168 Pfam PF13921 Myb-like DNA-binding domain 9 62 2.3E-6 T 14-10-2018 C2I25_19885 8431b572312c978c55455569a8c344b7 168 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 155 1.2E-56 T 14-10-2018 IPR014243 Transcription factor, RsfA C2I25_19885 8431b572312c978c55455569a8c344b7 168 SMART SM00717 5 59 0.0037 T 14-10-2018 IPR001005 SANT/Myb domain C2I25_19885 8431b572312c978c55455569a8c344b7 168 Gene3D G3DSA:1.10.10.60 8 86 6.3E-6 T 14-10-2018 C2I25_19885 8431b572312c978c55455569a8c344b7 168 SUPERFAMILY SSF46689 6 62 5.62E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 SMART SM00382 38 230 3.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 SMART SM00382 332 516 7.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 Pfam PF12558 ATP-binding cassette cobalt transporter 243 314 4.4E-14 T 14-10-2018 IPR022216 Putative ABC cobalt transporter C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 Gene3D G3DSA:3.40.50.300 8 256 1.5E-62 T 14-10-2018 C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 Pfam PF00005 ABC transporter 29 179 2.2E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 Pfam PF00005 ABC transporter 323 469 1.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 Gene3D G3DSA:3.40.50.300 303 554 3.5E-64 T 14-10-2018 C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 SUPERFAMILY SSF52540 10 243 1.33E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_26400 b0b74d1b7cdd7d3bfa2f060e6384c181 573 SUPERFAMILY SSF52540 301 536 7.78E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07330 4276a8f59e3bb35b5b3fad8b8153cb37 244 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 16 226 1.0E-54 T 14-10-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 C2I25_07330 4276a8f59e3bb35b5b3fad8b8153cb37 244 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 11 233 3.4E-82 T 14-10-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 Gene3D G3DSA:3.70.10.10 145 378 1.2E-134 T 14-10-2018 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 254 1.0E-36 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 380 3.0E-124 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 SUPERFAMILY SSF55979 257 380 3.84E-32 T 14-10-2018 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 SMART SM00480 17 376 1.7E-164 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 257 379 8.3E-38 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 6.6E-36 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 SUPERFAMILY SSF55979 1 127 8.05E-23 T 14-10-2018 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 PIRSF PIRSF000804 1 381 4.7E-117 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 Gene3D G3DSA:3.10.150.10 1 253 1.2E-134 T 14-10-2018 C2I25_11640 3ad3d2848816ff479e20f2caa6fc23a3 381 SUPERFAMILY SSF55979 133 254 3.77E-26 T 14-10-2018 C2I25_17140 51fb521e30e5e30a5ade684bbf27763f 611 Pfam PF01476 LysM domain 4 48 2.0E-15 T 14-10-2018 IPR018392 LysM domain C2I25_17140 51fb521e30e5e30a5ade684bbf27763f 611 SUPERFAMILY SSF54106 2 48 1.44E-11 T 14-10-2018 C2I25_17140 51fb521e30e5e30a5ade684bbf27763f 611 SMART SM00257 3 48 7.2E-17 T 14-10-2018 IPR018392 LysM domain C2I25_17140 51fb521e30e5e30a5ade684bbf27763f 611 Gene3D G3DSA:3.10.350.10 2 60 3.4E-17 T 14-10-2018 IPR036779 LysM domain superfamily C2I25_17140 51fb521e30e5e30a5ade684bbf27763f 611 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 6 49 4.0E-28 T 14-10-2018 IPR014248 Spore coat assembly protein SafA C2I25_19160 e10547976b7c2c0613998345767337e1 122 Pfam PF00583 Acetyltransferase (GNAT) family 35 98 4.1E-8 T 14-10-2018 IPR000182 GNAT domain C2I25_19160 e10547976b7c2c0613998345767337e1 122 SUPERFAMILY SSF55729 6 97 6.81E-12 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_19160 e10547976b7c2c0613998345767337e1 122 Gene3D G3DSA:3.40.630.30 18 117 1.2E-11 T 14-10-2018 C2I25_13690 e5ea74d8904676e6f8c1e6feb530de8b 118 TIGRFAM TIGR00494 crcB: protein CrcB 5 114 4.4E-24 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I25_13690 e5ea74d8904676e6f8c1e6feb530de8b 118 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 112 1.2E-24 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I25_13690 e5ea74d8904676e6f8c1e6feb530de8b 118 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 117 19.106 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 Gene3D G3DSA:1.20.1480.50 146 238 4.9E-13 T 14-10-2018 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 Gene3D G3DSA:1.10.287.130 239 305 6.7E-12 T 14-10-2018 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 Gene3D G3DSA:3.30.565.10 307 458 5.3E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 SUPERFAMILY SSF158472 185 232 1.28E-7 T 14-10-2018 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 SUPERFAMILY SSF47384 227 304 2.75E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 Pfam PF00672 HAMP domain 186 232 6.8E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 303 1.3E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 SMART SM00387 349 457 7.3E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.6E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 1.6E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 SMART SM00388 243 305 3.0E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 SMART SM00304 184 235 6.9E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 SUPERFAMILY SSF55874 308 448 1.44E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_25275 c0a1071b9fa5b4c069909f9b4ec77093 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 445 3.9E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_28025 6f096d8ff7caf2d11ef5244f56401bed 200 SUPERFAMILY SSF56399 3 195 4.6E-62 T 14-10-2018 C2I25_28025 6f096d8ff7caf2d11ef5244f56401bed 200 Gene3D G3DSA:1.10.3800.10 31 171 2.7E-86 T 14-10-2018 C2I25_28025 6f096d8ff7caf2d11ef5244f56401bed 200 Pfam PF10386 Protein of unknown function (DUF2441) 31 170 1.1E-66 T 14-10-2018 IPR018840 Protein of unknown function DUF2441 C2I25_28025 6f096d8ff7caf2d11ef5244f56401bed 200 Gene3D G3DSA:3.20.170.10 5 195 2.7E-86 T 14-10-2018 C2I25_03225 323f49c92674ac3b2ccfc3025911cb73 225 Gene3D G3DSA:3.30.1330.60 66 225 1.5E-42 T 14-10-2018 IPR036737 OmpA-like domain superfamily C2I25_03225 323f49c92674ac3b2ccfc3025911cb73 225 SUPERFAMILY SSF103088 107 223 5.49E-31 T 14-10-2018 IPR036737 OmpA-like domain superfamily C2I25_03225 323f49c92674ac3b2ccfc3025911cb73 225 Pfam PF00691 OmpA family 119 217 1.1E-17 T 14-10-2018 IPR006665 OmpA-like domain C2I25_03225 323f49c92674ac3b2ccfc3025911cb73 225 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 5 50 4.4E-13 T 14-10-2018 IPR025713 Motility protein B, N-terminal domain C2I25_18990 146f1c37c60ff1d9e3c44e518c2a7673 215 PIRSF PIRSF038973 2 213 1.1E-70 T 14-10-2018 IPR014196 Stage II sporulation protein M C2I25_18990 146f1c37c60ff1d9e3c44e518c2a7673 215 Pfam PF01944 Stage II sporulation protein M 26 202 2.1E-21 T 14-10-2018 IPR002798 Stage II sporulation protein M-like C2I25_18990 146f1c37c60ff1d9e3c44e518c2a7673 215 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 9 206 2.0E-81 T 14-10-2018 IPR014196 Stage II sporulation protein M C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 Gene3D G3DSA:3.90.1310.10 150 327 1.1E-51 T 14-10-2018 C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 Pfam PF03717 Penicillin-binding Protein dimerisation domain 150 317 2.5E-36 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 Gene3D G3DSA:3.40.710.10 331 661 1.4E-84 T 14-10-2018 C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 24 142 8.6E-41 T 14-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 Pfam PF00905 Penicillin binding protein transpeptidase domain 352 658 4.3E-66 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 SUPERFAMILY SSF54427 27 141 6.31E-34 T 14-10-2018 IPR032710 NTF2-like domain superfamily C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 Gene3D G3DSA:3.30.1390.30 171 242 1.1E-51 T 14-10-2018 C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 SUPERFAMILY SSF56519 144 331 8.89E-44 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 Gene3D G3DSA:3.10.450.100 23 138 7.9E-29 T 14-10-2018 C2I25_00265 38dfc5218c64a0226dc4ee50a363d983 661 SUPERFAMILY SSF56601 332 660 9.39E-82 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_09040 dcab122a6ca802f683a4d5992ed03b49 388 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 18 179 3.8E-41 T 14-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 C2I25_09040 dcab122a6ca802f683a4d5992ed03b49 388 Gene3D G3DSA:3.40.50.2000 190 352 1.4E-29 T 14-10-2018 C2I25_09040 dcab122a6ca802f683a4d5992ed03b49 388 SUPERFAMILY SSF53756 6 366 2.72E-34 T 14-10-2018 C2I25_09040 dcab122a6ca802f683a4d5992ed03b49 388 Hamap MF_01280 Processive diacylglycerol beta-glucosyltransferase [ugtP]. 1 388 57.524 T 14-10-2018 IPR023589 Processive diacylglycerol beta-glucosyltransferase GO:0047228 KEGG: 00561+2.4.1.315|MetaCyc: PWY-7817 C2I25_09040 dcab122a6ca802f683a4d5992ed03b49 388 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 220 348 1.1E-12 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 C2I25_03400 ae3918d3eacc74c8fb1a0298f4979824 303 Pfam PF00892 EamA-like transporter family 151 290 9.7E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_03400 ae3918d3eacc74c8fb1a0298f4979824 303 Pfam PF00892 EamA-like transporter family 10 142 1.0E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_03400 ae3918d3eacc74c8fb1a0298f4979824 303 SUPERFAMILY SSF103481 196 296 2.22E-16 T 14-10-2018 C2I25_03400 ae3918d3eacc74c8fb1a0298f4979824 303 SUPERFAMILY SSF103481 42 145 3.66E-12 T 14-10-2018 C2I25_26940 f8173f36c933e66d92da99d086f79d61 277 SUPERFAMILY SSF53474 5 274 2.4E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_26940 f8173f36c933e66d92da99d086f79d61 277 Pfam PF00561 alpha/beta hydrolase fold 24 151 2.6E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_26940 f8173f36c933e66d92da99d086f79d61 277 Gene3D G3DSA:3.40.50.1820 5 277 4.1E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_24680 1e9e401b007f1973ed1b7aaf26bed97d 522 Gene3D G3DSA:3.30.420.40 247 511 4.9E-55 T 14-10-2018 C2I25_24680 1e9e401b007f1973ed1b7aaf26bed97d 522 SUPERFAMILY SSF53067 3 251 3.0E-53 T 14-10-2018 C2I25_24680 1e9e401b007f1973ed1b7aaf26bed97d 522 PIRSF PIRSF000538 3 510 4.1E-122 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_24680 1e9e401b007f1973ed1b7aaf26bed97d 522 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 251 6.7E-47 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 C2I25_24680 1e9e401b007f1973ed1b7aaf26bed97d 522 SUPERFAMILY SSF53067 253 503 2.72E-49 T 14-10-2018 C2I25_24680 1e9e401b007f1973ed1b7aaf26bed97d 522 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 291 458 2.6E-18 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 C2I25_24680 1e9e401b007f1973ed1b7aaf26bed97d 522 Gene3D G3DSA:3.30.420.40 3 246 5.9E-57 T 14-10-2018 C2I25_23805 003f4290112547f1070c60a2b8f5e527 695 SUPERFAMILY SSF56601 55 377 6.52E-72 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_23805 003f4290112547f1070c60a2b8f5e527 695 Gene3D G3DSA:3.40.710.10 42 386 1.1E-73 T 14-10-2018 C2I25_23805 003f4290112547f1070c60a2b8f5e527 695 Pfam PF00144 Beta-lactamase 57 376 6.0E-62 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_11660 74d546a8d77cb3ff02c529e2d236a3ea 255 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 246 33.28 T 14-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 C2I25_11660 74d546a8d77cb3ff02c529e2d236a3ea 255 PRINTS PR01900 YidC translocation/secretion protein signature 197 221 6.4E-6 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I25_11660 74d546a8d77cb3ff02c529e2d236a3ea 255 PRINTS PR01900 YidC translocation/secretion protein signature 175 190 6.4E-6 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I25_11660 74d546a8d77cb3ff02c529e2d236a3ea 255 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 241 1.2E-67 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11660 74d546a8d77cb3ff02c529e2d236a3ea 255 Pfam PF02096 60Kd inner membrane protein 59 241 2.6E-61 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I25_11660 74d546a8d77cb3ff02c529e2d236a3ea 255 PRINTS PR00701 60kDa inner membrane protein signature 124 147 2.9E-15 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I25_11660 74d546a8d77cb3ff02c529e2d236a3ea 255 PRINTS PR00701 60kDa inner membrane protein signature 208 231 2.9E-15 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I25_05390 bcf06448f8cb519ceeb3a398dd07b96f 265 Hamap MF_00361 NAD kinase [nadK]. 1 263 24.691 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I25_05390 bcf06448f8cb519ceeb3a398dd07b96f 265 Gene3D G3DSA:3.40.50.10330 16 262 4.9E-97 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 C2I25_05390 bcf06448f8cb519ceeb3a398dd07b96f 265 SUPERFAMILY SSF111331 7 261 3.4E-64 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily C2I25_05390 bcf06448f8cb519ceeb3a398dd07b96f 265 Pfam PF01513 ATP-NAD kinase 31 188 2.0E-25 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I25_05390 bcf06448f8cb519ceeb3a398dd07b96f 265 Gene3D G3DSA:2.60.200.30 102 240 4.9E-97 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I25_24465 3f9e8c9f36266233ab446dda695d0326 405 Pfam PF00202 Aminotransferase class-III 19 393 1.4E-97 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_24465 3f9e8c9f36266233ab446dda695d0326 405 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 219 256 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_24465 3f9e8c9f36266233ab446dda695d0326 405 SUPERFAMILY SSF53383 11 394 2.18E-108 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_24465 3f9e8c9f36266233ab446dda695d0326 405 PIRSF PIRSF000521 121 399 2.0E-34 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_24465 3f9e8c9f36266233ab446dda695d0326 405 PIRSF PIRSF000521 6 129 4.2E-9 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_24465 3f9e8c9f36266233ab446dda695d0326 405 Gene3D G3DSA:3.90.1150.10 8 386 3.0E-122 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_24465 3f9e8c9f36266233ab446dda695d0326 405 Gene3D G3DSA:3.40.640.10 55 303 3.0E-122 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 SUPERFAMILY SSF56176 352 431 2.26E-15 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 Gene3D G3DSA:3.30.465.10 349 432 1.2E-15 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 Gene3D G3DSA:3.10.580.10 195 348 1.1E-48 T 14-10-2018 C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 SUPERFAMILY SSF54631 204 341 7.33E-30 T 14-10-2018 C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 SMART SM01091 354 431 1.3E-18 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 Pfam PF01595 Domain of unknown function DUF21 8 201 3.3E-51 T 14-10-2018 IPR002550 CNNM, transmembrane domain C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 Pfam PF00571 CBS domain 288 338 1.1E-6 T 14-10-2018 IPR000644 CBS domain C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 Pfam PF00571 CBS domain 218 270 0.0011 T 14-10-2018 IPR000644 CBS domain C2I25_08445 ef3ac34f0a0669b9c1d881fc74301053 432 Pfam PF03471 Transporter associated domain 356 430 2.3E-15 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_18285 7d533d713e66ea286e987dcdd2660ab9 105 SUPERFAMILY SSF46785 2 103 4.64E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_18285 7d533d713e66ea286e987dcdd2660ab9 105 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 1.8E-22 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_18285 7d533d713e66ea286e987dcdd2660ab9 105 Gene3D G3DSA:1.10.10.10 1 105 5.6E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.2E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.2E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 9.2E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 SMART SM00345 14 73 4.3E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 SUPERFAMILY SSF64288 63 239 2.04E-38 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 SMART SM00866 95 233 1.2E-24 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 SUPERFAMILY SSF46785 5 84 6.0E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 Pfam PF07702 UTRA domain 96 232 1.4E-31 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 Gene3D G3DSA:1.10.10.10 3 74 1.8E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20550 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 Gene3D G3DSA:3.40.1410.10 77 239 6.1E-31 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_16205 0134927ffbeb72c5c67fc85aa1cb5039 151 Gene3D G3DSA:3.40.630.30 7 151 3.9E-23 T 14-10-2018 C2I25_16205 0134927ffbeb72c5c67fc85aa1cb5039 151 SUPERFAMILY SSF55729 8 146 1.15E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_16205 0134927ffbeb72c5c67fc85aa1cb5039 151 Pfam PF00583 Acetyltransferase (GNAT) family 58 140 1.1E-14 T 14-10-2018 IPR000182 GNAT domain C2I25_23750 65fc3b7b54b40a27d957f85e95b9d4ec 126 SMART SM00345 15 74 2.1E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_23750 65fc3b7b54b40a27d957f85e95b9d4ec 126 SUPERFAMILY SSF46785 4 85 4.62E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23750 65fc3b7b54b40a27d957f85e95b9d4ec 126 Gene3D G3DSA:1.10.10.10 8 126 5.0E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23750 65fc3b7b54b40a27d957f85e95b9d4ec 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.9E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_11895 1dea5dd8df5c8de720671531327b4f39 117 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 9.6E-19 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_11895 1dea5dd8df5c8de720671531327b4f39 117 Gene3D G3DSA:1.10.10.10 1 105 4.4E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_11895 1dea5dd8df5c8de720671531327b4f39 117 SUPERFAMILY SSF46785 10 102 4.0E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_09915 a7d1ff388dd1a69f5bd5788d7e02261e 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 202 2.4E-47 T 14-10-2018 C2I25_09915 a7d1ff388dd1a69f5bd5788d7e02261e 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 8.5E-99 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09915 a7d1ff388dd1a69f5bd5788d7e02261e 227 SMART SM01211 1 219 8.2E-139 T 14-10-2018 C2I25_09915 a7d1ff388dd1a69f5bd5788d7e02261e 227 PIRSF PIRSF001586 1 222 1.9E-93 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09915 a7d1ff388dd1a69f5bd5788d7e02261e 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 217 46.338 T 14-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09915 a7d1ff388dd1a69f5bd5788d7e02261e 227 SUPERFAMILY SSF52317 2 219 1.62E-78 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_09915 a7d1ff388dd1a69f5bd5788d7e02261e 227 Gene3D G3DSA:3.40.50.880 1 220 1.2E-76 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_20360 d52626647a5289ae3046bd1c640f6611 180 SUPERFAMILY SSF56235 4 179 9.77E-60 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_20360 d52626647a5289ae3046bd1c640f6611 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 5.4E-85 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 C2I25_20360 d52626647a5289ae3046bd1c640f6611 180 Pfam PF00227 Proteasome subunit 5 178 3.8E-25 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 C2I25_20360 d52626647a5289ae3046bd1c640f6611 180 Gene3D G3DSA:3.60.20.10 2 180 8.7E-70 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_20360 d52626647a5289ae3046bd1c640f6611 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 41.219 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 C2I25_20360 d52626647a5289ae3046bd1c640f6611 180 PIRSF PIRSF039093 1 180 2.7E-85 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 C2I25_04215 e40f06d79c2bee7f81f818f998421749 351 Gene3D G3DSA:3.30.565.10 214 346 3.8E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_04215 e40f06d79c2bee7f81f818f998421749 351 SMART SM00387 252 345 2.6E-10 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04215 e40f06d79c2bee7f81f818f998421749 351 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 342 4.6E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_04215 e40f06d79c2bee7f81f818f998421749 351 PIRSF PIRSF037431 5 350 7.5E-136 T 14-10-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 C2I25_04215 e40f06d79c2bee7f81f818f998421749 351 Pfam PF07730 Histidine kinase 149 216 5.0E-20 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I25_04215 e40f06d79c2bee7f81f818f998421749 351 SUPERFAMILY SSF55874 220 342 2.23E-17 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_10395 2b908530f9609c9e839184219ba8890e 626 Pfam PF00005 ABC transporter 20 191 2.9E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10395 2b908530f9609c9e839184219ba8890e 626 Gene3D G3DSA:3.40.50.300 2 285 6.7E-73 T 14-10-2018 C2I25_10395 2b908530f9609c9e839184219ba8890e 626 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10395 2b908530f9609c9e839184219ba8890e 626 SUPERFAMILY SSF52540 323 534 2.18E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10395 2b908530f9609c9e839184219ba8890e 626 Gene3D G3DSA:3.40.50.300 298 559 3.3E-57 T 14-10-2018 C2I25_10395 2b908530f9609c9e839184219ba8890e 626 Pfam PF12848 ABC transporter 230 324 4.5E-23 T 14-10-2018 IPR032781 ABC-transporter extension domain C2I25_10395 2b908530f9609c9e839184219ba8890e 626 SUPERFAMILY SSF52540 6 244 3.68E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10395 2b908530f9609c9e839184219ba8890e 626 Pfam PF00005 ABC transporter 351 478 4.8E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10395 2b908530f9609c9e839184219ba8890e 626 SMART SM00382 28 243 8.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_10395 2b908530f9609c9e839184219ba8890e 626 SMART SM00382 359 522 4.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_22685 0153af54646d9ea87c78e411fed3d234 275 Pfam PF00753 Metallo-beta-lactamase superfamily 76 210 1.4E-6 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_22685 0153af54646d9ea87c78e411fed3d234 275 SUPERFAMILY SSF56281 59 232 3.41E-26 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_22685 0153af54646d9ea87c78e411fed3d234 275 Gene3D G3DSA:3.60.15.10 42 273 2.8E-13 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_22685 0153af54646d9ea87c78e411fed3d234 275 SMART SM00849 76 246 2.7E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_18050 1926e574f84876cdbe5f901cf6a41559 124 SUPERFAMILY SSF52309 1 92 1.34E-7 T 14-10-2018 C2I25_18050 1926e574f84876cdbe5f901cf6a41559 124 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 6 90 4.8E-8 T 14-10-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 C2I25_18050 1926e574f84876cdbe5f901cf6a41559 124 Gene3D G3DSA:3.40.50.450 1 124 1.1E-8 T 14-10-2018 C2I25_06950 55a06bec16e0b17f95b447c43da14830 489 SUPERFAMILY SSF52091 399 475 2.35E-11 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_06950 55a06bec16e0b17f95b447c43da14830 489 Pfam PF01740 STAS domain 402 471 2.1E-6 T 14-10-2018 IPR002645 STAS domain C2I25_06950 55a06bec16e0b17f95b447c43da14830 489 Gene3D G3DSA:3.30.750.24 386 476 1.8E-11 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_06950 55a06bec16e0b17f95b447c43da14830 489 Pfam PF00916 Sulfate permease family 8 134 2.7E-25 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I25_06950 55a06bec16e0b17f95b447c43da14830 489 Pfam PF00916 Sulfate permease family 140 359 3.9E-39 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I25_20940 5f0db5f61f267d49c2c2cde875dd355f 303 Gene3D G3DSA:3.40.1190.20 1 302 4.4E-112 T 14-10-2018 IPR029056 Ribokinase-like C2I25_20940 5f0db5f61f267d49c2c2cde875dd355f 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I25_20940 5f0db5f61f267d49c2c2cde875dd355f 303 SUPERFAMILY SSF53613 1 282 5.92E-71 T 14-10-2018 IPR029056 Ribokinase-like C2I25_20940 5f0db5f61f267d49c2c2cde875dd355f 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 2.3E-115 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 C2I25_20940 5f0db5f61f267d49c2c2cde875dd355f 303 PIRSF PIRSF000535 1 303 6.5E-94 T 14-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 C2I25_20940 5f0db5f61f267d49c2c2cde875dd355f 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I25_20940 5f0db5f61f267d49c2c2cde875dd355f 303 Pfam PF00294 pfkB family carbohydrate kinase 11 280 2.1E-54 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB C2I25_20940 5f0db5f61f267d49c2c2cde875dd355f 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 5.9E-113 T 14-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 C2I25_14100 4de597cadcf1aa4f2a047695c27cd5e1 215 Pfam PF14378 PAP2 superfamily 51 192 3.2E-10 T 14-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 C2I25_14100 4de597cadcf1aa4f2a047695c27cd5e1 215 SUPERFAMILY SSF48317 15 208 9.81E-6 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I25_04145 fc1ac5883e3558f06e960eefa344d6d2 266 Pfam PF01925 Sulfite exporter TauE/SafE 7 259 6.9E-57 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I25_20080 60e919374ee73c587704eadc7a98cebf 238 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 5 229 2.9E-64 T 14-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20080 60e919374ee73c587704eadc7a98cebf 238 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 228 3.3E-48 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20080 60e919374ee73c587704eadc7a98cebf 238 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 234 39.839 T 14-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20080 60e919374ee73c587704eadc7a98cebf 238 Gene3D G3DSA:3.20.20.70 1 237 7.0E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_20080 60e919374ee73c587704eadc7a98cebf 238 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20080 60e919374ee73c587704eadc7a98cebf 238 SMART SM00934 4 229 2.5E-92 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20080 60e919374ee73c587704eadc7a98cebf 238 SUPERFAMILY SSF51366 4 233 4.19E-73 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I25_22985 718f1c0d913439794f6527c3c052c119 255 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 255 2.9E-145 T 14-10-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 C2I25_22985 718f1c0d913439794f6527c3c052c119 255 Gene3D G3DSA:3.90.550.10 1 255 4.4E-71 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_22985 718f1c0d913439794f6527c3c052c119 255 SUPERFAMILY SSF53448 1 255 5.42E-66 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_22985 718f1c0d913439794f6527c3c052c119 255 Pfam PF00483 Nucleotidyl transferase 2 227 1.1E-19 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_22505 cd87680b3fe203c5818a16a99520cf42 259 SUPERFAMILY SSF56281 46 258 3.41E-41 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_22505 cd87680b3fe203c5818a16a99520cf42 259 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 113 132 - T 14-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 C2I25_22505 cd87680b3fe203c5818a16a99520cf42 259 ProSitePatterns PS00744 Beta-lactamases class B signature 2. 189 201 - T 14-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 C2I25_22505 cd87680b3fe203c5818a16a99520cf42 259 Gene3D G3DSA:3.60.15.10 26 259 3.3E-81 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_22505 cd87680b3fe203c5818a16a99520cf42 259 SMART SM00849 70 242 1.1E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_22505 cd87680b3fe203c5818a16a99520cf42 259 Pfam PF00753 Metallo-beta-lactamase superfamily 69 223 2.0E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_03770 f9e66cb6f58b446c33c0518380fd42e9 228 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 16 213 6.8E-41 T 14-10-2018 IPR010178 Integral membrane protein 1906 C2I25_03770 f9e66cb6f58b446c33c0518380fd42e9 228 Pfam PF07314 Protein of unknown function (DUF1461) 18 190 4.4E-45 T 14-10-2018 IPR010178 Integral membrane protein 1906 C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 Pfam PF00128 Alpha amylase, catalytic domain 376 575 1.8E-7 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 Pfam PF00128 Alpha amylase, catalytic domain 260 342 9.1E-6 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 SMART SM00642 238 613 1.3E-6 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 94 690 4.4E-269 T 14-10-2018 IPR011840 Pullulanase, type I C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 105 181 2.8E-14 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 Gene3D G3DSA:2.60.40.2320 1 95 1.1E-33 T 14-10-2018 C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 Gene3D G3DSA:2.60.40.1180 623 712 6.4E-25 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 SUPERFAMILY SSF51445 207 620 6.63E-120 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 SUPERFAMILY SSF81296 98 200 7.2E-22 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 Gene3D G3DSA:2.60.40.10 96 200 4.6E-30 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_15745 4829f5d303638bc220ae84acc8a0c8cf 713 Gene3D G3DSA:3.20.20.80 201 622 8.4E-174 T 14-10-2018 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 Gene3D G3DSA:1.10.630.10 8 411 2.2E-133 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 14-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00385 P450 superfamily signature 249 266 2.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00385 P450 superfamily signature 284 295 2.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00385 P450 superfamily signature 351 360 2.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00385 P450 superfamily signature 360 371 2.5E-6 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 203 225 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 302 329 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 100 111 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 351 360 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 360 371 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 284 295 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 146 162 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 330 345 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 PRINTS PR00359 B-class P450 signature 163 178 8.3E-56 T 14-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 SUPERFAMILY SSF48264 21 411 1.2E-97 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_26475 97804bf6da0247b848f6ae8d83025b07 411 Pfam PF00067 Cytochrome P450 195 380 4.8E-29 T 14-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 Gene3D G3DSA:2.130.10.10 341 497 1.4E-36 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 Gene3D G3DSA:2.130.10.10 285 340 1.3E-15 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 SUPERFAMILY SSF51004 199 491 3.14E-52 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 Pfam PF01391 Collagen triple helix repeat (20 copies) 89 142 3.4E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 Pfam PF01391 Collagen triple helix repeat (20 copies) 41 94 6.1E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 Pfam PF01391 Collagen triple helix repeat (20 copies) 134 192 3.2E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 18 36 5.9E-7 T 14-10-2018 IPR021201 Leader peptide, exosporium C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 Gene3D G3DSA:2.130.10.10 169 284 1.2E-24 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 411 442 3.6E-8 T 14-10-2018 IPR011964 YVTN beta-propeller repeat C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 199 237 1.1E-14 T 14-10-2018 IPR011964 YVTN beta-propeller repeat C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 364 402 2.9E-13 T 14-10-2018 IPR011964 YVTN beta-propeller repeat C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 242 278 5.5E-10 T 14-10-2018 IPR011964 YVTN beta-propeller repeat C2I25_27580 639ba6d70d2410a0aa1a42f10a3c3701 497 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 325 363 1.1E-12 T 14-10-2018 IPR011964 YVTN beta-propeller repeat C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 SUPERFAMILY SSF47384 198 267 7.26E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 Gene3D G3DSA:3.30.565.10 267 412 5.8E-60 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 Pfam PF07694 5TMR of 5TMR-LYT 23 179 8.8E-22 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 SUPERFAMILY SSF55874 258 414 8.91E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 Gene3D G3DSA:1.10.287.130 207 266 5.8E-60 T 14-10-2018 C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 5.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 5.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 5.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 5.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 413 1.9E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 SMART SM00388 203 269 7.2E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 SMART SM00387 309 415 2.1E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_26385 d9d1d2d130a8a533055e175e90d6ec89 422 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 265 2.0E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_15780 f10c94fd0b2418eea68e70d19b5d7d30 169 SUPERFAMILY SSF52972 1 165 1.09E-47 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I25_15780 f10c94fd0b2418eea68e70d19b5d7d30 169 Gene3D G3DSA:3.90.950.10 1 168 4.0E-49 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I25_15780 f10c94fd0b2418eea68e70d19b5d7d30 169 Pfam PF01931 Protein of unknown function DUF84 6 156 3.9E-44 T 14-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 C2I25_06990 d029472b59a57e6b71367be2eaa0e9da 205 Gene3D G3DSA:3.10.300.10 1 205 4.7E-73 T 14-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I25_06990 d029472b59a57e6b71367be2eaa0e9da 205 SUPERFAMILY SSF50486 3 204 8.63E-67 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 C2I25_06990 d029472b59a57e6b71367be2eaa0e9da 205 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 6 200 4.4E-64 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I25_06990 d029472b59a57e6b71367be2eaa0e9da 205 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 4 203 2.5E-62 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I25_06990 d029472b59a57e6b71367be2eaa0e9da 205 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 5 203 34.076 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I25_22705 9a53faefba2516eae7ddb5c3aa4855af 114 SUPERFAMILY SSF46785 2 106 2.05E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22705 9a53faefba2516eae7ddb5c3aa4855af 114 Pfam PF01638 HxlR-like helix-turn-helix 14 102 1.0E-37 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_22705 9a53faefba2516eae7ddb5c3aa4855af 114 Gene3D G3DSA:1.10.10.10 1 114 1.3E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 SUPERFAMILY SSF160996 193 361 6.54E-47 T 14-10-2018 C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 Gene3D G3DSA:1.10.8.260 279 343 1.8E-124 T 14-10-2018 IPR023166 HI0933-like insert domain superfamily C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 SUPERFAMILY SSF51905 1 415 1.4E-65 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.4E-10 T 14-10-2018 C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 1.4E-10 T 14-10-2018 C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 1.4E-10 T 14-10-2018 C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 Pfam PF03486 HI0933-like protein 3 413 1.5E-157 T 14-10-2018 C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 Gene3D G3DSA:2.40.30.10 192 360 1.8E-124 T 14-10-2018 C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 Gene3D G3DSA:3.50.50.60 6 409 1.8E-124 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 412 1.2E-145 T 14-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 4.0E-6 T 14-10-2018 C2I25_15715 c6c64b3b9d93da2b3963b99d972c34d3 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.0E-6 T 14-10-2018 C2I25_12170 ce6635e06ebb2be646c713e8c199370c 305 Pfam PF00005 ABC transporter 21 161 2.8E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_12170 ce6635e06ebb2be646c713e8c199370c 305 Gene3D G3DSA:3.40.50.300 1 239 8.4E-63 T 14-10-2018 C2I25_12170 ce6635e06ebb2be646c713e8c199370c 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_12170 ce6635e06ebb2be646c713e8c199370c 305 SMART SM00382 29 218 2.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_12170 ce6635e06ebb2be646c713e8c199370c 305 SUPERFAMILY SSF52540 3 225 1.45E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02435 c88262adc13efe1a92f19217cc366fc8 178 SUPERFAMILY SSF55068 4 166 1.96E-70 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_02435 c88262adc13efe1a92f19217cc366fc8 178 Pfam PF01625 Peptide methionine sulfoxide reductase 9 159 2.1E-59 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_02435 c88262adc13efe1a92f19217cc366fc8 178 Gene3D G3DSA:3.30.1060.10 1 166 1.6E-64 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_02435 c88262adc13efe1a92f19217cc366fc8 178 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 6 165 36.286 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_02435 c88262adc13efe1a92f19217cc366fc8 178 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 158 1.3E-62 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I25_01175 7204d6c052290375bfc0e7543cffd309 293 Gene3D G3DSA:3.30.200.20 1 98 9.7E-26 T 14-10-2018 C2I25_01175 7204d6c052290375bfc0e7543cffd309 293 Pfam PF01636 Phosphotransferase enzyme family 69 254 2.3E-19 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_01175 7204d6c052290375bfc0e7543cffd309 293 Gene3D G3DSA:3.90.1200.10 99 293 1.3E-56 T 14-10-2018 C2I25_01175 7204d6c052290375bfc0e7543cffd309 293 SUPERFAMILY SSF56112 8 261 6.13E-30 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_26190 9a11a2a68eb1c6b838099c236c1a4f7d 152 SUPERFAMILY SSF55729 3 147 4.33E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26190 9a11a2a68eb1c6b838099c236c1a4f7d 152 Pfam PF00583 Acetyltransferase (GNAT) family 50 135 3.0E-12 T 14-10-2018 IPR000182 GNAT domain C2I25_26190 9a11a2a68eb1c6b838099c236c1a4f7d 152 Gene3D G3DSA:3.40.630.30 48 150 2.5E-21 T 14-10-2018 C2I25_18010 d16b03e4e888100758e62f3cb819484f 370 PIRSF PIRSF001434 1 365 8.2E-123 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_18010 d16b03e4e888100758e62f3cb819484f 370 Gene3D G3DSA:3.90.1150.10 279 362 8.1E-26 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_18010 d16b03e4e888100758e62f3cb819484f 370 Gene3D G3DSA:3.90.1150.10 246 278 5.1E-6 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_18010 d16b03e4e888100758e62f3cb819484f 370 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 362 7.3E-133 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_18010 d16b03e4e888100758e62f3cb819484f 370 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_18010 d16b03e4e888100758e62f3cb819484f 370 SUPERFAMILY SSF53383 17 362 2.66E-102 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_18010 d16b03e4e888100758e62f3cb819484f 370 Gene3D G3DSA:3.40.640.10 3 245 3.9E-87 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_11550 348d26bab666e1de7802113d68a745d7 222 SUPERFAMILY SSF52540 14 215 1.2E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11550 348d26bab666e1de7802113d68a745d7 222 PIRSF PIRSF000705 2 220 1.6E-64 T 14-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 C2I25_11550 348d26bab666e1de7802113d68a745d7 222 Gene3D G3DSA:3.40.50.300 12 217 4.6E-58 T 14-10-2018 C2I25_11550 348d26bab666e1de7802113d68a745d7 222 Pfam PF01712 Deoxynucleoside kinase 15 214 1.8E-63 T 14-10-2018 IPR031314 Deoxynucleoside kinase domain C2I25_13285 26196f2773fe1a57fad7580012654ce0 180 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 121 176 8.8E-30 T 14-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal C2I25_13285 26196f2773fe1a57fad7580012654ce0 180 Gene3D G3DSA:3.30.505.50 134 180 2.5E-27 T 14-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily C2I25_13285 26196f2773fe1a57fad7580012654ce0 180 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 3.1E-32 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 C2I25_13285 26196f2773fe1a57fad7580012654ce0 180 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 180 25.332 T 14-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid C2I25_13285 26196f2773fe1a57fad7580012654ce0 180 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 1.4E-34 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 C2I25_13285 26196f2773fe1a57fad7580012654ce0 180 SUPERFAMILY SSF69754 2 103 8.37E-37 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like C2I25_13285 26196f2773fe1a57fad7580012654ce0 180 Gene3D G3DSA:3.30.160.100 1 95 4.6E-35 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 Gene3D G3DSA:3.40.1770.10 13 538 4.2E-259 T 14-10-2018 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 Pfam PF01175 Urocanase Rossmann-like domain 137 345 1.0E-92 T 14-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 SUPERFAMILY SSF111326 5 551 2.75E-266 T 14-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 550 0.0 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 Hamap MF_00577 Urocanate hydratase [hutU]. 4 552 51.574 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 ProSitePatterns PS01233 Urocanase signature. 438 453 - T 14-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 Pfam PF17391 Urocanase N-terminal domain 8 134 2.4E-63 T 14-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 Pfam PF17392 Urocanase C-terminal domain 348 542 9.9E-96 T 14-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 PIRSF PIRSF001423 1 552 4.1E-303 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21230 b28a86b0085b20e67d2785b02f50660f 552 Gene3D G3DSA:3.40.50.10730 138 345 4.2E-259 T 14-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_08660 89cb6a9a3006784abb0e986668dd5ed5 188 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 7 178 4.4E-56 T 14-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 C2I25_08660 89cb6a9a3006784abb0e986668dd5ed5 188 Gene3D G3DSA:3.20.20.400 1 185 1.2E-56 T 14-10-2018 IPR035928 GlpP-like superfamily C2I25_08660 89cb6a9a3006784abb0e986668dd5ed5 188 SUPERFAMILY SSF110391 5 178 5.89E-50 T 14-10-2018 IPR035928 GlpP-like superfamily C2I25_08660 89cb6a9a3006784abb0e986668dd5ed5 188 PIRSF PIRSF016897 1 184 1.3E-69 T 14-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 C2I25_21600 11838223530301d25755f8860d587514 297 Pfam PF00005 ABC transporter 19 156 3.7E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21600 11838223530301d25755f8860d587514 297 SMART SM00382 26 204 9.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_21600 11838223530301d25755f8860d587514 297 SUPERFAMILY SSF52540 2 218 1.1E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21600 11838223530301d25755f8860d587514 297 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_21600 11838223530301d25755f8860d587514 297 Gene3D G3DSA:3.40.50.300 1 231 4.1E-53 T 14-10-2018 C2I25_09045 8638a8f917a94e08cc047c7cb8234559 243 Gene3D G3DSA:3.20.20.70 1 243 1.4E-98 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_09045 8638a8f917a94e08cc047c7cb8234559 243 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 5 241 3.3E-103 T 14-10-2018 IPR012838 Pyruvate formate-lyase 1 activating enzyme GO:0043365|GO:0055114 C2I25_09045 8638a8f917a94e08cc047c7cb8234559 243 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 14-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 C2I25_09045 8638a8f917a94e08cc047c7cb8234559 243 Pfam PF13353 4Fe-4S single cluster domain 15 146 7.2E-23 T 14-10-2018 C2I25_09045 8638a8f917a94e08cc047c7cb8234559 243 SUPERFAMILY SSF102114 21 221 1.44E-27 T 14-10-2018 C2I25_09045 8638a8f917a94e08cc047c7cb8234559 243 Pfam PF04055 Radical SAM superfamily 23 184 2.4E-30 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_15815 4bd59aebe3f1bdbcf3fea2b9f7899808 372 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 47 118 4.7E-8 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 C2I25_15815 4bd59aebe3f1bdbcf3fea2b9f7899808 372 Gene3D G3DSA:3.90.1170.20 12 118 1.1E-16 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 C2I25_15815 4bd59aebe3f1bdbcf3fea2b9f7899808 372 Gene3D G3DSA:3.20.20.70 120 333 1.2E-64 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_15815 4bd59aebe3f1bdbcf3fea2b9f7899808 372 SUPERFAMILY SSF51690 128 355 1.18E-47 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 C2I25_15815 4bd59aebe3f1bdbcf3fea2b9f7899808 372 SUPERFAMILY SSF54675 18 128 6.28E-22 T 14-10-2018 C2I25_15815 4bd59aebe3f1bdbcf3fea2b9f7899808 372 PIRSF PIRSF000484 15 364 3.7E-66 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 C2I25_08545 5819432b1c807741b7825257f560ce33 268 SUPERFAMILY SSF53927 6 261 3.31E-75 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_08545 5819432b1c807741b7825257f560ce33 268 PIRSF PIRSF015626 2 265 3.6E-76 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I25_08545 5819432b1c807741b7825257f560ce33 268 Pfam PF02634 FdhD/NarQ family 26 261 5.4E-78 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I25_08545 5819432b1c807741b7825257f560ce33 268 Gene3D G3DSA:3.40.140.10 117 266 1.8E-46 T 14-10-2018 C2I25_08545 5819432b1c807741b7825257f560ce33 268 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 262 31.147 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I25_08545 5819432b1c807741b7825257f560ce33 268 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 261 1.1E-71 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I25_08545 5819432b1c807741b7825257f560ce33 268 Gene3D G3DSA:3.10.20.10 28 110 1.8E-14 T 14-10-2018 C2I25_12410 11fc00fdcb18efe63cfe027bea14f2e9 583 Gene3D G3DSA:1.10.390.10 415 569 2.0E-30 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily C2I25_12410 11fc00fdcb18efe63cfe027bea14f2e9 583 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 246 404 1.8E-31 T 14-10-2018 IPR013856 Peptidase M4 domain GO:0004222 C2I25_12410 11fc00fdcb18efe63cfe027bea14f2e9 583 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 132 9.1E-11 T 14-10-2018 IPR011096 FTP domain C2I25_12410 11fc00fdcb18efe63cfe027bea14f2e9 583 Gene3D G3DSA:3.10.170.10 245 408 1.9E-32 T 14-10-2018 C2I25_12410 11fc00fdcb18efe63cfe027bea14f2e9 583 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 418 569 3.3E-26 T 14-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 C2I25_12410 11fc00fdcb18efe63cfe027bea14f2e9 583 SUPERFAMILY SSF55486 241 569 4.72E-55 T 14-10-2018 C2I25_04380 97ea029b2dd3df37880571d6887e2005 211 SUPERFAMILY SSF53850 3 206 1.33E-66 T 14-10-2018 C2I25_04380 97ea029b2dd3df37880571d6887e2005 211 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 3 208 59.402 T 14-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 C2I25_04380 97ea029b2dd3df37880571d6887e2005 211 Gene3D G3DSA:3.40.190.10 6 196 4.7E-76 T 14-10-2018 C2I25_04380 97ea029b2dd3df37880571d6887e2005 211 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 184 3.9E-63 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 C2I25_04380 97ea029b2dd3df37880571d6887e2005 211 Pfam PF01634 ATP phosphoribosyltransferase 53 204 3.7E-51 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 C2I25_04380 97ea029b2dd3df37880571d6887e2005 211 Gene3D G3DSA:3.40.190.10 94 176 4.7E-76 T 14-10-2018 C2I25_04380 97ea029b2dd3df37880571d6887e2005 211 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 14-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 Gene3D G3DSA:3.40.630.10 7 358 9.6E-117 T 14-10-2018 C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 361 4.2E-88 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 Pfam PF07687 Peptidase dimerisation domain 180 269 9.5E-11 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 PIRSF PIRSF005962 1 376 7.5E-104 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 Gene3D G3DSA:3.30.70.360 173 287 9.6E-117 T 14-10-2018 C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 SUPERFAMILY SSF53187 4 369 1.65E-65 T 14-10-2018 C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 3 372 62.468 T 14-10-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 SUPERFAMILY SSF55031 178 283 4.97E-28 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_19585 d822d54e250589c0137c9d76c2c71fc3 376 Pfam PF01546 Peptidase family M20/M25/M40 67 370 6.9E-25 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_01275 db0c64870a1caa7173d4ab4669628d4f 196 Gene3D G3DSA:3.40.50.1240 1 196 6.8E-48 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_01275 db0c64870a1caa7173d4ab4669628d4f 196 SMART SM00855 2 150 9.0E-20 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_01275 db0c64870a1caa7173d4ab4669628d4f 196 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 190 1.1E-44 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_01275 db0c64870a1caa7173d4ab4669628d4f 196 SUPERFAMILY SSF53254 1 194 4.32E-47 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_01275 db0c64870a1caa7173d4ab4669628d4f 196 PIRSF PIRSF000709 1 184 1.4E-14 T 14-10-2018 C2I25_14610 270df797338a70221e063fa15d668ada 383 Gene3D G3DSA:3.90.1150.10 12 378 2.3E-147 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_14610 270df797338a70221e063fa15d668ada 383 Pfam PF00155 Aminotransferase class I and II 69 378 3.1E-37 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_14610 270df797338a70221e063fa15d668ada 383 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 382 5.9E-143 T 14-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 C2I25_14610 270df797338a70221e063fa15d668ada 383 SUPERFAMILY SSF53383 1 381 1.07E-96 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_14610 270df797338a70221e063fa15d668ada 383 Gene3D G3DSA:3.40.640.10 63 286 2.3E-147 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_00075 3b97cbc531d0728d85e8be8f743015a6 149 Gene3D G3DSA:1.20.1250.20 1 133 3.3E-6 T 14-10-2018 C2I25_00075 3b97cbc531d0728d85e8be8f743015a6 149 SUPERFAMILY SSF103473 2 138 8.11E-11 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_10380 2374e0a24f23241906bceae414d85093 575 Gene3D G3DSA:3.40.190.10 80 556 7.7E-129 T 14-10-2018 C2I25_10380 2374e0a24f23241906bceae414d85093 575 SUPERFAMILY SSF53850 65 560 2.57E-122 T 14-10-2018 C2I25_10380 2374e0a24f23241906bceae414d85093 575 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 115 137 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site C2I25_10380 2374e0a24f23241906bceae414d85093 575 Gene3D G3DSA:3.10.105.10 325 542 7.7E-129 T 14-10-2018 C2I25_10380 2374e0a24f23241906bceae414d85093 575 Gene3D G3DSA:3.90.76.10 98 229 7.7E-129 T 14-10-2018 C2I25_10380 2374e0a24f23241906bceae414d85093 575 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 494 1.4E-85 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_10380 2374e0a24f23241906bceae414d85093 575 PIRSF PIRSF002741 6 571 2.1E-110 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_21125 3b83347b28dc5750a3ed68cca3ce90cb 137 Pfam PF00293 NUDIX domain 8 116 7.0E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_21125 3b83347b28dc5750a3ed68cca3ce90cb 137 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_21125 3b83347b28dc5750a3ed68cca3ce90cb 137 Gene3D G3DSA:3.90.79.10 7 137 3.3E-26 T 14-10-2018 C2I25_21125 3b83347b28dc5750a3ed68cca3ce90cb 137 PRINTS PR00502 NUDIX hydrolase family signature 46 61 1.2E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_21125 3b83347b28dc5750a3ed68cca3ce90cb 137 PRINTS PR00502 NUDIX hydrolase family signature 32 46 1.2E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_21125 3b83347b28dc5750a3ed68cca3ce90cb 137 SUPERFAMILY SSF55811 5 132 3.11E-28 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 583 592 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 456 471 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 SMART SM00382 389 533 1.9E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 SUPERFAMILY SSF55785 112 216 1.05E-16 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Gene3D G3DSA:3.40.50.720 1 89 5.0E-6 T 14-10-2018 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 SUPERFAMILY SSF52540 368 608 6.63E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 SUPERFAMILY SSF51735 1 101 1.65E-11 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Gene3D G3DSA:3.40.50.300 356 541 1.5E-61 T 14-10-2018 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Pfam PF02954 Bacterial regulatory protein, Fis family 643 682 8.4E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Gene3D G3DSA:1.10.10.60 631 686 3.2E-13 T 14-10-2018 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 SUPERFAMILY SSF46689 583 683 2.82E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Gene3D G3DSA:1.10.8.60 542 624 1.1E-21 T 14-10-2018 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Pfam PF00158 Sigma-54 interaction domain 369 537 6.1E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Gene3D G3DSA:3.30.450.20 110 220 1.1E-22 T 14-10-2018 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Gene3D G3DSA:3.30.450.20 224 340 4.4E-17 T 14-10-2018 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Pfam PF00989 PAS fold 239 340 1.2E-11 T 14-10-2018 IPR013767 PAS fold GO:0006355 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 Pfam PF00989 PAS fold 119 219 4.6E-14 T 14-10-2018 IPR013767 PAS fold GO:0006355 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 121 228 1.6E-15 T 14-10-2018 IPR000014 PAS domain C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 236 350 5.8E-17 T 14-10-2018 IPR000014 PAS domain C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 SUPERFAMILY SSF55785 236 336 3.14E-15 T 14-10-2018 IPR035965 PAS domain superfamily C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 393 406 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 665 685 6.9E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 648 665 6.9E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 SMART SM00091 237 302 1.0E-6 T 14-10-2018 IPR000014 PAS domain C2I25_18570 54eda19ff5e09a7ff1349f764333afde 690 SMART SM00091 118 184 6.5E-12 T 14-10-2018 IPR000014 PAS domain C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 Gene3D G3DSA:1.10.287.130 242 311 2.6E-15 T 14-10-2018 C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 SMART SM00304 187 239 8.1E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 308 3.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 Gene3D G3DSA:1.20.1480.50 152 241 1.1E-9 T 14-10-2018 C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 SMART SM00387 356 464 3.2E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 SUPERFAMILY SSF158472 188 235 1.83E-7 T 14-10-2018 C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 462 5.4E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 SUPERFAMILY SSF55874 314 463 3.67E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 SMART SM00388 247 312 5.2E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 SUPERFAMILY SSF47384 234 310 5.1E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 Gene3D G3DSA:3.30.565.10 312 462 6.9E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_12885 fc1357fc1927b4d5a10c5c2c74490985 476 Pfam PF00672 HAMP domain 188 234 5.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_19065 b1c723974578da1b63884d62839bd8a8 293 SUPERFAMILY SSF52540 2 219 1.92E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_19065 b1c723974578da1b63884d62839bd8a8 293 SMART SM00382 26 202 5.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_19065 b1c723974578da1b63884d62839bd8a8 293 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_19065 b1c723974578da1b63884d62839bd8a8 293 Gene3D G3DSA:3.40.50.300 1 247 2.0E-52 T 14-10-2018 C2I25_19065 b1c723974578da1b63884d62839bd8a8 293 Pfam PF00005 ABC transporter 17 154 2.4E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_15920 0917692bfec0dc56b7f66918688615bf 308 SUPERFAMILY SSF55347 126 266 1.8E-41 T 14-10-2018 C2I25_15920 0917692bfec0dc56b7f66918688615bf 308 Gene3D G3DSA:3.40.50.720 1 120 2.2E-31 T 14-10-2018 C2I25_15920 0917692bfec0dc56b7f66918688615bf 308 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 1.0E-25 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I25_15920 0917692bfec0dc56b7f66918688615bf 308 Gene3D G3DSA:3.30.360.10 121 308 3.1E-52 T 14-10-2018 C2I25_15920 0917692bfec0dc56b7f66918688615bf 308 SUPERFAMILY SSF51735 4 138 3.09E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_24635 d0b1f442a7821259883516c7343ed013 415 SUPERFAMILY SSF53720 3 414 7.07E-110 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_24635 d0b1f442a7821259883516c7343ed013 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 41.88 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I25_24635 d0b1f442a7821259883516c7343ed013 415 PIRSF PIRSF000151 1 415 3.1E-178 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 C2I25_24635 d0b1f442a7821259883516c7343ed013 415 Gene3D G3DSA:3.40.309.10 224 372 8.0E-164 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_24635 d0b1f442a7821259883516c7343ed013 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 343 - T 14-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I25_24635 d0b1f442a7821259883516c7343ed013 415 Pfam PF00171 Aldehyde dehydrogenase family 94 280 1.8E-10 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_24635 d0b1f442a7821259883516c7343ed013 415 Gene3D G3DSA:3.40.605.10 17 409 8.0E-164 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_24635 d0b1f442a7821259883516c7343ed013 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 404 3.8E-168 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I25_22200 60cb0f400228d6253db0c6f6b564cce2 329 Pfam PF13602 Zinc-binding dehydrogenase 183 326 2.4E-36 T 14-10-2018 C2I25_22200 60cb0f400228d6253db0c6f6b564cce2 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 C2I25_22200 60cb0f400228d6253db0c6f6b564cce2 329 SUPERFAMILY SSF51735 113 293 2.87E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22200 60cb0f400228d6253db0c6f6b564cce2 329 SUPERFAMILY SSF50129 3 145 4.72E-33 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_22200 60cb0f400228d6253db0c6f6b564cce2 329 SMART SM00829 8 326 1.2E-23 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_22200 60cb0f400228d6253db0c6f6b564cce2 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 87 1.6E-8 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_22200 60cb0f400228d6253db0c6f6b564cce2 329 Gene3D G3DSA:3.90.180.10 13 326 6.7E-106 T 14-10-2018 C2I25_22200 60cb0f400228d6253db0c6f6b564cce2 329 Gene3D G3DSA:3.40.50.720 121 297 6.7E-106 T 14-10-2018 C2I25_05020 5559a21f0adffb8982d51c96458c1302 290 Pfam PF13256 Domain of unknown function (DUF4047) 33 157 3.6E-59 T 14-10-2018 IPR025120 Domain of unknown function DUF4047 C2I25_16485 5640f4ffeba7c97e254aedec5bbbca60 237 Pfam PF02517 CAAX protease self-immunity 144 232 1.5E-20 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_14565 f0e0e3bc403eb4f303e6bf704194619d 127 SUPERFAMILY SSF54637 5 125 8.87E-29 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_14565 f0e0e3bc403eb4f303e6bf704194619d 127 Pfam PF03061 Thioesterase superfamily 35 113 6.8E-13 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I25_14565 f0e0e3bc403eb4f303e6bf704194619d 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 5 120 1.0E-35 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 C2I25_14565 f0e0e3bc403eb4f303e6bf704194619d 127 Gene3D G3DSA:3.10.129.10 1 127 1.4E-51 T 14-10-2018 C2I25_25755 201195efdcefa8f34e8773d6225be79c 112 Gene3D G3DSA:3.30.70.100 1 110 1.1E-9 T 14-10-2018 C2I25_25755 201195efdcefa8f34e8773d6225be79c 112 SUPERFAMILY SSF54909 1 107 2.12E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_25755 201195efdcefa8f34e8773d6225be79c 112 Pfam PF07978 NIPSNAP 8 74 6.2E-8 T 14-10-2018 IPR012577 NIPSNAP C2I25_08460 f5a237eace12b1b32808978c8d1698a4 338 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 101 248 2.8E-45 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_08460 f5a237eace12b1b32808978c8d1698a4 338 Gene3D G3DSA:1.10.260.150 61 338 4.5E-87 T 14-10-2018 C2I25_08460 f5a237eace12b1b32808978c8d1698a4 338 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 101 249 1.7E-41 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 Pfam PF01752 Collagenase 299 633 1.9E-80 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 Gene3D G3DSA:1.10.390.20 517 654 2.6E-56 T 14-10-2018 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 Gene3D G3DSA:2.60.120.380 764 878 4.5E-24 T 14-10-2018 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 Pfam PF08453 Peptidase family M9 N-terminal 94 273 3.5E-55 T 14-10-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 Gene3D G3DSA:3.30.980.50 655 763 6.5E-48 T 14-10-2018 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 799 864 5.8E-6 T 14-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 Gene3D G3DSA:1.10.1740.190 373 516 3.3E-59 T 14-10-2018 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 SUPERFAMILY SSF89260 769 877 1.57E-29 T 14-10-2018 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 500 518 5.1E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 446 460 5.1E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 526 541 5.1E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 160 178 5.1E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_24455 f44ef2c451737b2cf0b4f3ad86b8cb18 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 463 479 5.1E-32 T 14-10-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 C2I25_15140 f7dd4a7f886e62a804ae81c6cbe5d75f 223 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 9 208 1.2E-67 T 14-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 C2I25_15140 f7dd4a7f886e62a804ae81c6cbe5d75f 223 Gene3D G3DSA:1.10.1760.20 5 212 3.7E-62 T 14-10-2018 C2I25_13570 1aa734858d043d1a8df1090b372d8c3f 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 76 1.1E-24 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I25_13570 1aa734858d043d1a8df1090b372d8c3f 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 1.0E-10 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I25_13570 1aa734858d043d1a8df1090b372d8c3f 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.0E-10 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I25_13570 1aa734858d043d1a8df1090b372d8c3f 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.0E-10 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I25_13570 1aa734858d043d1a8df1090b372d8c3f 77 Pfam PF03840 Preprotein translocase SecG subunit 4 75 3.6E-23 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I25_10560 208e4b6ebc44355c4ccfdf0db5f8d3ef 257 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 255 2.8E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_10560 208e4b6ebc44355c4ccfdf0db5f8d3ef 257 SMART SM00382 34 225 2.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_10560 208e4b6ebc44355c4ccfdf0db5f8d3ef 257 Gene3D G3DSA:3.40.50.300 3 257 8.6E-86 T 14-10-2018 C2I25_10560 208e4b6ebc44355c4ccfdf0db5f8d3ef 257 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_10560 208e4b6ebc44355c4ccfdf0db5f8d3ef 257 Pfam PF00005 ABC transporter 25 176 1.3E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_10560 208e4b6ebc44355c4ccfdf0db5f8d3ef 257 SUPERFAMILY SSF52540 5 248 2.33E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23280 e67618e0f213265033178665105bd339 551 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_23280 e67618e0f213265033178665105bd339 551 Gene3D G3DSA:3.40.50.300 4 241 7.3E-65 T 14-10-2018 C2I25_23280 e67618e0f213265033178665105bd339 551 Pfam PF00005 ABC transporter 310 453 6.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_23280 e67618e0f213265033178665105bd339 551 SUPERFAMILY SSF52540 282 519 5.2E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23280 e67618e0f213265033178665105bd339 551 SUPERFAMILY SSF52540 6 233 2.2E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23280 e67618e0f213265033178665105bd339 551 Gene3D G3DSA:3.40.50.300 277 526 8.3E-60 T 14-10-2018 C2I25_23280 e67618e0f213265033178665105bd339 551 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_23280 e67618e0f213265033178665105bd339 551 Pfam PF00005 ABC transporter 22 171 8.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_23280 e67618e0f213265033178665105bd339 551 SMART SM00382 31 220 9.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_23280 e67618e0f213265033178665105bd339 551 SMART SM00382 319 502 9.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_07925 94a9e120ecaac18abcaf5ff6d376e60f 466 Pfam PF07664 Ferrous iron transport protein B C terminus 251 300 2.9E-14 T 14-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 C2I25_07925 94a9e120ecaac18abcaf5ff6d376e60f 466 Pfam PF07670 Nucleoside recognition 309 434 6.3E-18 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I25_07925 94a9e120ecaac18abcaf5ff6d376e60f 466 Pfam PF07670 Nucleoside recognition 139 228 4.0E-9 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 Gene3D G3DSA:1.20.58.100 397 507 1.4E-22 T 14-10-2018 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 SUPERFAMILY SSF51905 3 391 3.48E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 SUPERFAMILY SSF46977 410 493 1.96E-23 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 Pfam PF02910 Fumarate reductase flavoprotein C-term 412 493 1.2E-12 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 332 354 3.0E-5 T 14-10-2018 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.0E-5 T 14-10-2018 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 4 490 2.7E-163 T 14-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 Pfam PF00890 FAD binding domain 5 369 1.7E-86 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 Gene3D G3DSA:3.90.700.10 229 324 2.2E-134 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 Gene3D G3DSA:3.50.50.60 5 380 2.2E-134 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_17125 765ca3114a9c59af9fdc30c15fba760d 509 SUPERFAMILY SSF56425 219 329 1.79E-33 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I25_23115 64fae3184e4ba0d39e14a1e8df3b5848 240 SUPERFAMILY SSF55729 30 236 6.45E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_23115 64fae3184e4ba0d39e14a1e8df3b5848 240 Gene3D G3DSA:3.40.630.30 97 239 6.6E-12 T 14-10-2018 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 Gene3D G3DSA:2.40.110.10 124 225 4.6E-19 T 14-10-2018 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 SUPERFAMILY SSF56645 4 219 3.14E-39 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 PIRSF PIRSF016578 139 381 2.0E-14 T 14-10-2018 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 PIRSF PIRSF016578 2 107 2.6E-11 T 14-10-2018 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 Gene3D G3DSA:1.10.540.10 5 123 3.1E-20 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 Gene3D G3DSA:1.20.140.10 240 379 3.9E-24 T 14-10-2018 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 217 1.9E-16 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 SUPERFAMILY SSF47203 240 380 1.61E-21 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 96 1.9E-9 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I25_24190 21bf14103e21f69fe15087504eca78b1 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 360 7.0E-12 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 Gene3D G3DSA:2.40.10.10 72 187 9.0E-26 T 14-10-2018 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 SUPERFAMILY SSF50494 84 304 1.56E-58 T 14-10-2018 IPR009003 Peptidase S1, PA clan C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 Pfam PF13180 PDZ domain 307 400 1.2E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 Gene3D G3DSA:2.30.42.10 310 412 5.3E-23 T 14-10-2018 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 Pfam PF13365 Trypsin-like peptidase domain 124 269 1.9E-31 T 14-10-2018 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 PRINTS PR00834 HtrA/DegQ protease family signature 136 148 1.5E-43 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 PRINTS PR00834 HtrA/DegQ protease family signature 157 177 1.5E-43 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 1.5E-43 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 PRINTS PR00834 HtrA/DegQ protease family signature 262 279 1.5E-43 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 PRINTS PR00834 HtrA/DegQ protease family signature 352 364 1.5E-43 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 PRINTS PR00834 HtrA/DegQ protease family signature 198 222 1.5E-43 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 SUPERFAMILY SSF50156 288 403 4.99E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 SMART SM00228 307 395 1.6E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 C2I25_21555 5d6cea46891ba9edd355ca48099b7b8c 413 Gene3D G3DSA:2.40.10.10 189 309 3.2E-40 T 14-10-2018 C2I25_23915 618a93354a1c4cec1bd24c32e015784a 134 Hamap MF_01624 Arsenate reductase [arsC]. 2 132 48.211 T 14-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 C2I25_23915 618a93354a1c4cec1bd24c32e015784a 134 SUPERFAMILY SSF52788 4 129 3.66E-44 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily C2I25_23915 618a93354a1c4cec1bd24c32e015784a 134 Gene3D G3DSA:3.40.50.2300 2 132 4.3E-53 T 14-10-2018 C2I25_23915 618a93354a1c4cec1bd24c32e015784a 134 SMART SM00226 5 132 8.5E-55 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I25_23915 618a93354a1c4cec1bd24c32e015784a 134 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 7 129 6.6E-63 T 14-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 C2I25_23915 618a93354a1c4cec1bd24c32e015784a 134 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 129 2.3E-24 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I25_23205 576a491a47bf915d218dc73f6871ecc4 227 Pfam PF00881 Nitroreductase family 18 205 5.8E-28 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_23205 576a491a47bf915d218dc73f6871ecc4 227 SUPERFAMILY SSF55469 12 225 6.41E-56 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_23205 576a491a47bf915d218dc73f6871ecc4 227 Gene3D G3DSA:3.40.109.10 2 227 2.7E-62 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_05765 5677a7dec1d151946fbca9b5463785bb 529 Gene3D G3DSA:3.20.20.360 2 407 9.2E-204 T 14-10-2018 C2I25_05765 5677a7dec1d151946fbca9b5463785bb 529 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 21 529 1.1E-252 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I25_05765 5677a7dec1d151946fbca9b5463785bb 529 Gene3D G3DSA:1.20.1220.12 408 529 1.2E-51 T 14-10-2018 C2I25_05765 5677a7dec1d151946fbca9b5463785bb 529 SUPERFAMILY SSF51645 6 528 2.62E-198 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I25_05765 5677a7dec1d151946fbca9b5463785bb 529 PIRSF PIRSF001363 1 529 2.0E-264 T 14-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I25_05765 5677a7dec1d151946fbca9b5463785bb 529 ProSitePatterns PS00510 Malate synthase signature. 263 278 - T 14-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I25_05765 5677a7dec1d151946fbca9b5463785bb 529 Pfam PF01274 Malate synthase 10 527 6.2E-216 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I25_24655 4eb10f5d923457f0c79ccce12050eb8c 111 SUPERFAMILY SSF54909 4 103 7.72E-23 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_24655 4eb10f5d923457f0c79ccce12050eb8c 111 Gene3D G3DSA:3.30.70.100 1 111 4.0E-50 T 14-10-2018 C2I25_24655 4eb10f5d923457f0c79ccce12050eb8c 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 81 3.0E-15 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I25_01910 7ea1df86bad467e97cc70083ff455075 573 Gene3D G3DSA:3.40.50.300 318 569 7.6E-73 T 14-10-2018 C2I25_01910 7ea1df86bad467e97cc70083ff455075 573 Pfam PF00005 ABC transporter 352 501 4.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_01910 7ea1df86bad467e97cc70083ff455075 573 Gene3D G3DSA:1.20.1560.10 4 317 8.1E-39 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_01910 7ea1df86bad467e97cc70083ff455075 573 SUPERFAMILY SSF52540 328 565 3.73E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01910 7ea1df86bad467e97cc70083ff455075 573 Pfam PF00664 ABC transporter transmembrane region 20 265 2.6E-24 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_01910 7ea1df86bad467e97cc70083ff455075 573 SMART SM00382 361 547 3.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_01910 7ea1df86bad467e97cc70083ff455075 573 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 18 542 2.0E-171 T 14-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 C2I25_01910 7ea1df86bad467e97cc70083ff455075 573 SUPERFAMILY SSF90123 9 308 7.06E-47 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_25600 aa5f2f2adbaba68bfd8fec27b2bf675f 397 Gene3D G3DSA:3.40.50.2000 217 380 1.7E-117 T 14-10-2018 C2I25_25600 aa5f2f2adbaba68bfd8fec27b2bf675f 397 SUPERFAMILY SSF53756 1 391 2.39E-73 T 14-10-2018 C2I25_25600 aa5f2f2adbaba68bfd8fec27b2bf675f 397 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 232 375 2.5E-23 T 14-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 C2I25_25600 aa5f2f2adbaba68bfd8fec27b2bf675f 397 Gene3D G3DSA:3.40.50.2000 5 391 1.7E-117 T 14-10-2018 C2I25_25600 aa5f2f2adbaba68bfd8fec27b2bf675f 397 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 394 8.8E-110 T 14-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 298 4.2E-133 T 14-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 SUPERFAMILY SSF51735 1 153 1.35E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 SUPERFAMILY SSF48179 165 295 8.16E-41 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 154 1.1E-43 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 SMART SM01350 167 298 4.5E-6 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 8.4E-28 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 8.4E-28 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 8.4E-28 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 21 8.4E-28 T 14-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 276 1.2E-23 T 14-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 Gene3D G3DSA:3.40.50.720 1 166 4.6E-51 T 14-10-2018 C2I25_00105 cf7542b20c0d71df72734d9571da65d7 298 Gene3D G3DSA:1.10.1040.10 167 297 2.6E-50 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_12945 48d69ed05cbbf8d2251236af70868f2b 132 Pfam PF14271 Domain of unknown function (DUF4359) 16 119 5.0E-18 T 14-10-2018 IPR025578 Protein of unknown function DUF4359 C2I25_24790 e362e1c572fd25f394fb130050bcf9ab 1170 Pfam PF13289 SIR2-like domain 120 246 3.5E-16 T 14-10-2018 IPR039444 SIR2-like domain C2I25_24790 e362e1c572fd25f394fb130050bcf9ab 1170 SUPERFAMILY SSF52467 22 216 5.61E-14 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_24790 e362e1c572fd25f394fb130050bcf9ab 1170 Pfam PF13212 Domain of unknown function (DUF4020) 981 1156 6.1E-75 T 14-10-2018 IPR025093 Domain of unknown function DUF4020 C2I25_12305 aaa0ad35ddd86589542115e6a78fdc61 135 Gene3D G3DSA:1.10.1660.10 1 133 8.4E-32 T 14-10-2018 C2I25_12305 aaa0ad35ddd86589542115e6a78fdc61 135 SMART SM00422 2 72 7.7E-31 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_12305 aaa0ad35ddd86589542115e6a78fdc61 135 Pfam PF13411 MerR HTH family regulatory protein 2 70 3.4E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_12305 aaa0ad35ddd86589542115e6a78fdc61 135 SUPERFAMILY SSF46955 1 121 2.93E-26 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 SMART SM00388 124 190 6.2E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 Gene3D G3DSA:1.10.287.130 74 185 8.5E-25 T 14-10-2018 C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 SUPERFAMILY SSF158472 76 121 1.26E-5 T 14-10-2018 C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 SMART SM00387 234 346 1.0E-39 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 SUPERFAMILY SSF47384 107 190 2.16E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 343 2.0E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 SUPERFAMILY SSF55874 180 346 5.76E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 343 3.8E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 3.8E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 3.8E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 324 3.8E-19 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 Gene3D G3DSA:3.30.565.10 195 352 1.5E-47 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_01825 c1c0ad26a6e6a87c5b5eb00762010509 355 Pfam PF00512 His Kinase A (phospho-acceptor) domain 124 189 3.0E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_06700 95ec7c17322571a0ca44f1c8793a13b6 295 SUPERFAMILY SSF103481 40 139 3.66E-10 T 14-10-2018 C2I25_06700 95ec7c17322571a0ca44f1c8793a13b6 295 Pfam PF00892 EamA-like transporter family 146 277 4.3E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_06700 95ec7c17322571a0ca44f1c8793a13b6 295 Pfam PF00892 EamA-like transporter family 6 136 1.0E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_06700 95ec7c17322571a0ca44f1c8793a13b6 295 SUPERFAMILY SSF103481 186 278 1.83E-14 T 14-10-2018 C2I25_14435 8e192b5373139817f8903437b1756a49 356 Gene3D G3DSA:3.50.50.100 1 355 2.5E-79 T 14-10-2018 C2I25_14435 8e192b5373139817f8903437b1756a49 356 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 289 3.4E-40 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_14435 8e192b5373139817f8903437b1756a49 356 SUPERFAMILY SSF51905 1 308 5.46E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_14435 8e192b5373139817f8903437b1756a49 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 3.8E-7 T 14-10-2018 C2I25_14435 8e192b5373139817f8903437b1756a49 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 3.8E-7 T 14-10-2018 C2I25_14435 8e192b5373139817f8903437b1756a49 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.8E-7 T 14-10-2018 C2I25_14435 8e192b5373139817f8903437b1756a49 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 7.8E-9 T 14-10-2018 C2I25_14435 8e192b5373139817f8903437b1756a49 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.8E-9 T 14-10-2018 C2I25_14435 8e192b5373139817f8903437b1756a49 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 7.8E-9 T 14-10-2018 C2I25_14435 8e192b5373139817f8903437b1756a49 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 7.8E-9 T 14-10-2018 C2I25_00530 ad752e4b86aafc002da270a497dc5f3d 111 SUPERFAMILY SSF50249 1 109 7.54E-41 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_00530 ad752e4b86aafc002da270a497dc5f3d 111 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 106 4.2E-33 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 C2I25_00530 ad752e4b86aafc002da270a497dc5f3d 111 Gene3D G3DSA:2.40.50.140 1 110 2.5E-41 T 14-10-2018 C2I25_00530 ad752e4b86aafc002da270a497dc5f3d 111 Pfam PF00436 Single-strand binding protein family 2 103 7.6E-35 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 C2I25_00530 ad752e4b86aafc002da270a497dc5f3d 111 PIRSF PIRSF002070 1 111 4.1E-36 T 14-10-2018 C2I25_00530 ad752e4b86aafc002da270a497dc5f3d 111 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 32.174 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 C2I25_18640 98fce161777110665f29fb2cc7e270de 144 Gene3D G3DSA:3.40.30.10 24 141 7.9E-53 T 14-10-2018 C2I25_18640 98fce161777110665f29fb2cc7e270de 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 7 141 1.5E-62 T 14-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family C2I25_18640 98fce161777110665f29fb2cc7e270de 144 Pfam PF06491 Disulphide isomerase 7 141 2.8E-61 T 14-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family C2I25_04220 5af8d6b7d0dc1d9da2d553137e010d98 246 PIRSF PIRSF031509 5 246 4.1E-74 T 14-10-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 C2I25_04220 5af8d6b7d0dc1d9da2d553137e010d98 246 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 131 243 1.0E-34 T 14-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF C2I25_07950 64b1a6e9bdfcee3f626b5bc1361150cd 490 Pfam PF00474 Sodium:solute symporter family 34 427 1.6E-22 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I25_07950 64b1a6e9bdfcee3f626b5bc1361150cd 490 Gene3D G3DSA:1.20.1730.10 4 490 2.0E-34 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I25_07100 44735f81d263990f3f4508447a710134 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I25_07100 44735f81d263990f3f4508447a710134 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I25_07100 44735f81d263990f3f4508447a710134 479 Gene3D G3DSA:3.40.605.10 23 255 7.0E-159 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_07100 44735f81d263990f3f4508447a710134 479 Gene3D G3DSA:3.40.309.10 258 437 7.0E-159 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_07100 44735f81d263990f3f4508447a710134 479 Pfam PF00171 Aldehyde dehydrogenase family 15 472 8.8E-157 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_07100 44735f81d263990f3f4508447a710134 479 SUPERFAMILY SSF53720 5 476 1.44E-150 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_18120 ecf1217a15e3c3675bb6b1028a79a799 123 Pfam PF14173 ComG operon protein 7 31 122 4.7E-26 T 14-10-2018 IPR020372 Competence operon G protein 7, ComGG C2I25_01205 8e79e9969ea7954064da1a59810686a8 208 Pfam PF07853 Protein of unknown function (DUF1648) 9 53 2.7E-9 T 14-10-2018 IPR012867 Domain of unknown function DUF1648 C2I25_01205 8e79e9969ea7954064da1a59810686a8 208 PIRSF PIRSF038959 1 203 2.5E-64 T 14-10-2018 IPR026272 Immunity protein SdpI C2I25_18280 b7660ca046964ce87af223fe49db4f2b 226 SUPERFAMILY SSF158560 4 99 7.06E-29 T 14-10-2018 C2I25_18280 b7660ca046964ce87af223fe49db4f2b 226 Pfam PF06570 Protein of unknown function (DUF1129) 35 225 2.6E-10 T 14-10-2018 IPR009214 Protein of unknown function DUF1129 C2I25_17445 ac95e1c92ca9a6a8b4c7f61123d23455 272 Pfam PF00005 ABC transporter 18 165 2.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_17445 ac95e1c92ca9a6a8b4c7f61123d23455 272 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_17445 ac95e1c92ca9a6a8b4c7f61123d23455 272 SMART SM00382 26 215 2.2E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_17445 ac95e1c92ca9a6a8b4c7f61123d23455 272 Gene3D G3DSA:3.40.50.300 2 250 1.7E-65 T 14-10-2018 C2I25_17445 ac95e1c92ca9a6a8b4c7f61123d23455 272 SUPERFAMILY SSF52540 2 227 2.72E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10830 7807bf09e7b6d20c8768ebdf331c7865 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 28.431 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10830 7807bf09e7b6d20c8768ebdf331c7865 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 120 2.7E-48 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10830 7807bf09e7b6d20c8768ebdf331c7865 120 Pfam PF01196 Ribosomal protein L17 16 120 1.9E-39 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10830 7807bf09e7b6d20c8768ebdf331c7865 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10830 7807bf09e7b6d20c8768ebdf331c7865 120 Gene3D G3DSA:3.90.1030.10 1 120 6.6E-50 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10830 7807bf09e7b6d20c8768ebdf331c7865 120 SUPERFAMILY SSF64263 2 120 1.57E-44 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20855 02b1a9592b7f6e51da81b364551b08ee 272 Gene3D G3DSA:3.40.50.1820 14 272 7.0E-89 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_20855 02b1a9592b7f6e51da81b364551b08ee 272 SUPERFAMILY SSF53474 5 269 4.12E-64 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_20855 02b1a9592b7f6e51da81b364551b08ee 272 Pfam PF00756 Putative esterase 26 221 6.5E-22 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 43.574 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 Pfam PF13484 4Fe-4S double cluster binding domain 187 250 7.7E-16 T 14-10-2018 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 SUPERFAMILY SSF48371 295 373 1.82E-10 T 14-10-2018 IPR016024 Armadillo-type fold C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 Pfam PF13646 HEAT repeats 300 365 1.8E-9 T 14-10-2018 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 Gene3D G3DSA:1.25.10.110 295 370 3.6E-10 T 14-10-2018 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 SMART SM00567 E-Z type HEAT repeats 330 359 0.0037 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 SMART SM00567 E-Z type HEAT repeats 298 327 89.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 5.0E-18 T 14-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 SUPERFAMILY SSF54862 164 252 3.56E-17 T 14-10-2018 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 342 9.1E-129 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 C2I25_08775 e8eb1363fb0b916f1ed24e8305cba1f5 380 Gene3D G3DSA:3.30.70.20 182 260 1.9E-5 T 14-10-2018 C2I25_11315 76f5db152ace5102a3f86804bd045ab4 217 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 130 2.9E-47 T 14-10-2018 IPR014242 Spore cortex biosynthesis protein, YabQ C2I25_11315 76f5db152ace5102a3f86804bd045ab4 217 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 2.6E-23 T 14-10-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like C2I25_14180 17cfd2d18ee69dc6d9e202da70ae1450 268 SUPERFAMILY SSF53850 27 266 1.6E-80 T 14-10-2018 C2I25_14180 17cfd2d18ee69dc6d9e202da70ae1450 268 Gene3D G3DSA:3.40.190.10 30 263 4.2E-97 T 14-10-2018 C2I25_14180 17cfd2d18ee69dc6d9e202da70ae1450 268 Pfam PF03180 NLPA lipoprotein 28 266 6.9E-89 T 14-10-2018 IPR004872 Lipoprotein NlpA family C2I25_14180 17cfd2d18ee69dc6d9e202da70ae1450 268 PIRSF PIRSF002854 1 267 8.8E-100 T 14-10-2018 IPR004872 Lipoprotein NlpA family C2I25_14180 17cfd2d18ee69dc6d9e202da70ae1450 268 Gene3D G3DSA:3.40.190.10 109 217 4.2E-97 T 14-10-2018 C2I25_04850 d5fddffdb3fa513223e4e084e3803848 150 Gene3D G3DSA:1.10.10.10 16 127 1.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04850 d5fddffdb3fa513223e4e084e3803848 150 Pfam PF03551 Transcriptional regulator PadR-like family 32 103 3.5E-18 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_04850 d5fddffdb3fa513223e4e084e3803848 150 TIGRFAM TIGR02719 repress_PhaQ: poly-beta-hydroxybutyrate-responsive repressor 4 141 1.8E-88 T 14-10-2018 IPR014091 Transcriptional repressor poly-beta-hydroxybutyrate-responsive C2I25_04850 d5fddffdb3fa513223e4e084e3803848 150 SUPERFAMILY SSF46785 15 121 6.49E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23350 52238f9dde3908e7d1596a5b14266813 419 SUPERFAMILY SSF56601 9 410 1.23E-80 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_23350 52238f9dde3908e7d1596a5b14266813 419 Gene3D G3DSA:3.40.710.10 32 419 6.2E-116 T 14-10-2018 C2I25_23350 52238f9dde3908e7d1596a5b14266813 419 Pfam PF00144 Beta-lactamase 109 395 2.5E-37 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_00060 0783803a4e78b00437f7c493769342b6 500 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 199 1.2E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_00060 0783803a4e78b00437f7c493769342b6 500 Gene3D G3DSA:3.40.190.10 241 499 1.3E-97 T 14-10-2018 C2I25_00060 0783803a4e78b00437f7c493769342b6 500 Gene3D G3DSA:1.10.3720.10 13 203 1.1E-35 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_00060 0783803a4e78b00437f7c493769342b6 500 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 230 495 2.4E-69 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 C2I25_00060 0783803a4e78b00437f7c493769342b6 500 SUPERFAMILY SSF53850 230 498 2.44E-75 T 14-10-2018 C2I25_00060 0783803a4e78b00437f7c493769342b6 500 SUPERFAMILY SSF161098 20 195 2.62E-40 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_00060 0783803a4e78b00437f7c493769342b6 500 Gene3D G3DSA:3.40.190.120 334 437 1.3E-97 T 14-10-2018 C2I25_07340 fbf7e731f0e1489f7d80beed5735ca1d 224 Pfam PF00005 ABC transporter 21 169 4.3E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_07340 fbf7e731f0e1489f7d80beed5735ca1d 224 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_07340 fbf7e731f0e1489f7d80beed5735ca1d 224 Gene3D G3DSA:3.40.50.300 1 223 3.1E-68 T 14-10-2018 C2I25_07340 fbf7e731f0e1489f7d80beed5735ca1d 224 SUPERFAMILY SSF52540 1 221 3.45E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07340 fbf7e731f0e1489f7d80beed5735ca1d 224 SMART SM00382 30 217 1.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_21890 e388e56508f8515d727cdc29a78fa0f2 281 Gene3D G3DSA:3.30.420.10 2 224 2.2E-43 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_21890 e388e56508f8515d727cdc29a78fa0f2 281 Pfam PF00929 Exonuclease 23 174 1.7E-22 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_21890 e388e56508f8515d727cdc29a78fa0f2 281 SUPERFAMILY SSF53098 5 179 1.43E-28 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_21890 e388e56508f8515d727cdc29a78fa0f2 281 SMART SM00479 6 183 2.7E-19 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 2.4E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 2.4E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 2.4E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 307 318 2.4E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 2.4E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 10 329 83.52 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 151 2.4E-47 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 Gene3D G3DSA:3.40.50.1370 8 325 4.2E-137 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 SUPERFAMILY SSF53671 7 330 6.15E-106 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 Gene3D G3DSA:3.40.50.1370 154 315 4.2E-137 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 11 328 9.2E-127 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 326 1.5E-56 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 273 8.5E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 8.5E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 8.5E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_09485 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 293 316 8.5E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 SUPERFAMILY SSF63418 7 103 4.71E-25 T 14-10-2018 IPR035911 MurE/MurF, N-terminal C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 Pfam PF01225 Mur ligase family, catalytic domain 27 101 9.0E-11 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 Gene3D G3DSA:3.40.1390.10 2 84 3.6E-23 T 14-10-2018 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 SUPERFAMILY SSF53244 319 457 2.56E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 Gene3D G3DSA:3.90.190.20 317 458 2.5E-41 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 Pfam PF08245 Mur ligase middle domain 111 298 5.8E-49 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 457 2.7E-139 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 Gene3D G3DSA:3.40.1190.10 87 316 5.4E-70 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 SUPERFAMILY SSF53623 106 315 1.44E-52 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 320 398 4.1E-16 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I25_10295 73a26a9dd96eb6571d6a817b0c910022 458 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 458 35.916 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_07110 a4dc097fc9f6195f080028be74ee1642 276 Pfam PF01177 Asp/Glu/Hydantoin racemase 10 217 3.8E-36 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_07110 a4dc097fc9f6195f080028be74ee1642 276 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 184 194 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_07110 a4dc097fc9f6195f080028be74ee1642 276 SUPERFAMILY SSF53681 115 263 1.46E-37 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_07110 a4dc097fc9f6195f080028be74ee1642 276 Gene3D G3DSA:3.40.50.1860 99 211 4.7E-95 T 14-10-2018 C2I25_07110 a4dc097fc9f6195f080028be74ee1642 276 TIGRFAM TIGR00067 glut_race: glutamate racemase 10 257 2.9E-80 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_07110 a4dc097fc9f6195f080028be74ee1642 276 SUPERFAMILY SSF53681 10 111 9.48E-35 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_07110 a4dc097fc9f6195f080028be74ee1642 276 Hamap MF_00258 Glutamate racemase [murI]. 8 259 38.069 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_07110 a4dc097fc9f6195f080028be74ee1642 276 Gene3D G3DSA:3.40.50.1860 10 256 4.7E-95 T 14-10-2018 C2I25_06975 505730e2d67b331b07d0f02f2c6b9c4b 340 Pfam PF00395 S-layer homology domain 168 207 7.5E-8 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06975 505730e2d67b331b07d0f02f2c6b9c4b 340 Pfam PF00395 S-layer homology domain 286 328 5.5E-4 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06975 505730e2d67b331b07d0f02f2c6b9c4b 340 Pfam PF00395 S-layer homology domain 222 265 3.7E-11 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06975 505730e2d67b331b07d0f02f2c6b9c4b 340 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 18 137 7.3E-25 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_06975 505730e2d67b331b07d0f02f2c6b9c4b 340 Gene3D G3DSA:3.40.80.10 7 171 1.6E-46 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_06975 505730e2d67b331b07d0f02f2c6b9c4b 340 SMART SM00644 8 153 4.4E-24 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_06975 505730e2d67b331b07d0f02f2c6b9c4b 340 SUPERFAMILY SSF55846 3 154 7.46E-44 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 SUPERFAMILY SSF46785 10 81 2.09E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 Pfam PF07702 UTRA domain 99 231 2.1E-21 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 6.7E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.3E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.3E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 SMART SM00866 98 234 1.3E-14 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 SMART SM00345 18 77 2.2E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 SUPERFAMILY SSF64288 65 239 9.74E-29 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 Gene3D G3DSA:3.40.1410.10 75 229 1.3E-24 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_14955 9d84a4cf88e17cf3f8fdd0b8bb23db74 241 Gene3D G3DSA:1.10.10.10 10 74 6.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15655 8601776e47127f00136bceaef9408c88 77 Gene3D G3DSA:3.10.20.30 1 77 7.8E-23 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_15655 8601776e47127f00136bceaef9408c88 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 1.2E-23 T 14-10-2018 C2I25_15655 8601776e47127f00136bceaef9408c88 77 SUPERFAMILY SSF54285 1 77 8.04E-19 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp C2I25_15655 8601776e47127f00136bceaef9408c88 77 Pfam PF02597 ThiS family 4 77 4.8E-18 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 C2I25_12155 30b285b3c78073af79d86645b445d9d0 208 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 193 2.3E-9 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_16305 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:2.40.33.10 70 166 5.7E-196 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF52935 321 473 1.83E-42 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:3.50.30.10 474 585 2.1E-34 T 14-10-2018 C2I25_16305 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:3.40.1380.20 334 468 5.7E-196 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:3.20.20.60 2 333 5.7E-196 T 14-10-2018 C2I25_16305 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF52009 465 583 4.19E-31 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 C2I25_16305 4141e922cb2611afd160998c61693f56 585 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 1.4E-190 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF50800 70 165 7.33E-27 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily C2I25_16305 4141e922cb2611afd160998c61693f56 585 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 14-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 267 291 8.3E-80 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 215 241 8.3E-80 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 242 266 8.3E-80 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 59 75 8.3E-80 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 311 327 8.3E-80 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 184 198 8.3E-80 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 292 310 8.3E-80 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 504 575 2.0E-21 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 C2I25_16305 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF51621 1 340 5.93E-104 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I25_16305 4141e922cb2611afd160998c61693f56 585 Pfam PF00224 Pyruvate kinase, barrel domain 1 342 2.7E-156 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_16305 4141e922cb2611afd160998c61693f56 585 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 470 4.6E-36 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I25_09630 cc1e8b2d324bc1b9382a05d9da299d58 409 Gene3D G3DSA:3.30.200.20 1 117 1.2E-36 T 14-10-2018 C2I25_09630 cc1e8b2d324bc1b9382a05d9da299d58 409 Pfam PF01636 Phosphotransferase enzyme family 34 271 1.3E-12 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_09630 cc1e8b2d324bc1b9382a05d9da299d58 409 SUPERFAMILY SSF56112 6 402 7.89E-84 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_09630 cc1e8b2d324bc1b9382a05d9da299d58 409 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 409 173.767 T 14-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I25_09630 cc1e8b2d324bc1b9382a05d9da299d58 409 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 35 398 2.4E-97 T 14-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I25_09630 cc1e8b2d324bc1b9382a05d9da299d58 409 Gene3D G3DSA:3.90.1200.10 118 405 1.7E-97 T 14-10-2018 C2I25_09630 cc1e8b2d324bc1b9382a05d9da299d58 409 PIRSF PIRSF031134 2 405 1.7E-162 T 14-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I25_16540 e76b9bfebf936ec5b995493e4edcf390 94 Hamap MF_02013 Cell division protein ZapA [zapA]. 8 92 28.685 T 14-10-2018 IPR023688 Cell division protein ZapA, firmicutes GO:0051301 C2I25_16540 e76b9bfebf936ec5b995493e4edcf390 94 Pfam PF05164 Cell division protein ZapA 16 88 2.2E-18 T 14-10-2018 IPR007838 Cell division protein ZapA-like C2I25_16540 e76b9bfebf936ec5b995493e4edcf390 94 SUPERFAMILY SSF102829 15 90 6.02E-21 T 14-10-2018 IPR036192 Cell division protein ZapA-like superfamily C2I25_16415 432c41f854f9fd0fe90754b93c2092a7 312 Gene3D G3DSA:3.40.50.300 108 304 4.8E-54 T 14-10-2018 C2I25_16415 432c41f854f9fd0fe90754b93c2092a7 312 SUPERFAMILY SSF52540 144 277 3.42E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16415 432c41f854f9fd0fe90754b93c2092a7 312 SMART SM00382 161 285 0.0012 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_16415 432c41f854f9fd0fe90754b93c2092a7 312 Pfam PF01695 IstB-like ATP binding protein 151 275 2.8E-13 T 14-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 C2I25_16415 432c41f854f9fd0fe90754b93c2092a7 312 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 1.2E-30 T 14-10-2018 IPR009928 Primosomal DnaI, N-terminal C2I25_11920 2c132e4976dd12da7032fe710910ce1f 94 Pfam PF00665 Integrase core domain 4 64 4.6E-8 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 C2I25_11920 2c132e4976dd12da7032fe710910ce1f 94 SUPERFAMILY SSF53098 3 61 1.23E-7 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_07490 c147b8800f5023ce7bf442d9964e7293 420 Pfam PF04734 Neutral/alkaline non-lysosomal ceramidase, N-terminal 4 217 6.6E-13 T 14-10-2018 IPR031329 Neutral/alkaline non-lysosomal ceramidase, N-terminal KEGG: 00600+3.5.1.23|MetaCyc: PWY-6483|MetaCyc: PWY-7119|Reactome: R-HSA-1660662 C2I25_04005 92df1d9e861f712f066cc99fb728ca06 204 SUPERFAMILY SSF51261 25 149 6.28E-42 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_04005 92df1d9e861f712f066cc99fb728ca06 204 Gene3D G3DSA:2.70.70.10 15 150 6.0E-39 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_04005 92df1d9e861f712f066cc99fb728ca06 204 Pfam PF01476 LysM domain 162 203 8.8E-13 T 14-10-2018 IPR018392 LysM domain C2I25_04005 92df1d9e861f712f066cc99fb728ca06 204 SMART SM00257 161 204 1.9E-10 T 14-10-2018 IPR018392 LysM domain C2I25_04005 92df1d9e861f712f066cc99fb728ca06 204 Pfam PF01551 Peptidase family M23 46 139 1.3E-28 T 14-10-2018 IPR016047 Peptidase M23 C2I25_04005 92df1d9e861f712f066cc99fb728ca06 204 SUPERFAMILY SSF54106 161 203 1.7E-10 T 14-10-2018 C2I25_04005 92df1d9e861f712f066cc99fb728ca06 204 Gene3D G3DSA:3.10.350.10 158 204 1.9E-14 T 14-10-2018 IPR036779 LysM domain superfamily C2I25_06420 07e5f5e32b1ee8931aefe74395cb6292 380 SUPERFAMILY SSF52172 2 156 2.56E-36 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_06420 07e5f5e32b1ee8931aefe74395cb6292 380 Gene3D G3DSA:3.60.40.10 134 378 2.8E-50 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_06420 07e5f5e32b1ee8931aefe74395cb6292 380 SMART SM00448 1 122 4.4E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_06420 07e5f5e32b1ee8931aefe74395cb6292 380 Gene3D G3DSA:3.40.50.2300 1 132 2.6E-38 T 14-10-2018 C2I25_06420 07e5f5e32b1ee8931aefe74395cb6292 380 SMART SM00331 163 377 1.1E-23 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_06420 07e5f5e32b1ee8931aefe74395cb6292 380 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 190 377 3.7E-38 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_06420 07e5f5e32b1ee8931aefe74395cb6292 380 SUPERFAMILY SSF81606 179 376 1.62E-7 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_06420 07e5f5e32b1ee8931aefe74395cb6292 380 Pfam PF00072 Response regulator receiver domain 3 122 8.7E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12560 ce4fd9cc7395bc55c4d7e29c83a70b9d 203 Pfam PF01613 Flavin reductase like domain 23 175 2.5E-23 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 C2I25_12560 ce4fd9cc7395bc55c4d7e29c83a70b9d 203 SMART SM00903 20 176 7.7E-26 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 C2I25_12560 ce4fd9cc7395bc55c4d7e29c83a70b9d 203 Gene3D G3DSA:2.30.110.10 1 203 3.5E-63 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I25_12560 ce4fd9cc7395bc55c4d7e29c83a70b9d 203 SUPERFAMILY SSF50475 4 199 1.18E-44 T 14-10-2018 C2I25_19735 9ff3018b3a912ff431f8c3fde1d73b54 442 SUPERFAMILY SSF52540 26 420 3.5E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_19735 9ff3018b3a912ff431f8c3fde1d73b54 442 Pfam PF02562 PhoH-like protein 233 437 5.3E-53 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 C2I25_19735 9ff3018b3a912ff431f8c3fde1d73b54 442 Pfam PF13638 PIN domain 5 147 3.6E-32 T 14-10-2018 IPR002716 PIN domain C2I25_19735 9ff3018b3a912ff431f8c3fde1d73b54 442 Gene3D G3DSA:3.40.50.300 231 441 4.5E-69 T 14-10-2018 C2I25_19735 9ff3018b3a912ff431f8c3fde1d73b54 442 Gene3D G3DSA:3.40.50.1010 2 149 8.7E-20 T 14-10-2018 C2I25_19735 9ff3018b3a912ff431f8c3fde1d73b54 442 SMART SM00670 3 135 4.8E-18 T 14-10-2018 IPR002716 PIN domain C2I25_18270 fbfea2129e6f5009aad2552b577638a3 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 68.46 T 14-10-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I25_18270 fbfea2129e6f5009aad2552b577638a3 278 SUPERFAMILY SSF55681 5 278 1.49E-68 T 14-10-2018 C2I25_18270 fbfea2129e6f5009aad2552b577638a3 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 6.1E-28 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I25_18270 fbfea2129e6f5009aad2552b577638a3 278 Gene3D G3DSA:3.30.930.10 4 278 2.7E-69 T 14-10-2018 C2I25_13220 2ddf17e3e4c7d9b34c9abccc62a76fac 245 Pfam PF01522 Polysaccharide deacetylase 42 164 6.1E-27 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_13220 2ddf17e3e4c7d9b34c9abccc62a76fac 245 Gene3D G3DSA:3.20.20.370 28 236 6.9E-57 T 14-10-2018 C2I25_13220 2ddf17e3e4c7d9b34c9abccc62a76fac 245 SUPERFAMILY SSF88713 40 229 1.01E-51 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_20040 92aa2fda15d4070aca9f6b557c8aabc6 180 SUPERFAMILY SSF53271 6 174 3.8E-44 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_20040 92aa2fda15d4070aca9f6b557c8aabc6 180 Gene3D G3DSA:3.40.50.2020 1 180 6.0E-63 T 14-10-2018 C2I25_20040 92aa2fda15d4070aca9f6b557c8aabc6 180 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 39.353 T 14-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 C2I25_20040 92aa2fda15d4070aca9f6b557c8aabc6 180 Pfam PF00156 Phosphoribosyl transferase domain 8 163 1.1E-20 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 Gene3D G3DSA:3.50.50.60 127 248 5.8E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 Hamap MF_01685 Ferredoxin--NADP reductase. 6 333 37.361 T 14-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 307 1.3E-28 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 1.8E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 1.8E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 1.8E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.8E-19 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 Gene3D G3DSA:3.50.50.60 7 308 5.8E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.8E-18 T 14-10-2018 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 7.8E-18 T 14-10-2018 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 7.8E-18 T 14-10-2018 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 7.8E-18 T 14-10-2018 C2I25_09595 042ab79c2cfee88bb3fa86a303ae0994 349 SUPERFAMILY SSF51905 1 318 5.96E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_11945 633e673a95191210ee730190e9a554e1 208 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 91 3.6E-29 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 PIRSF PIRSF000349 1 208 4.7E-77 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 SUPERFAMILY SSF54719 94 204 3.4E-42 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 197 1.7E-37 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 Gene3D G3DSA:1.10.287.990 21 91 1.8E-31 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 Gene3D G3DSA:2.40.500.20 92 208 1.9E-49 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 3.9E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 3.9E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 3.9E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 3.9E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 3.9E-23 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_11945 633e673a95191210ee730190e9a554e1 208 SUPERFAMILY SSF46609 3 92 3.01E-35 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 Gene3D G3DSA:1.10.240.10 223 325 1.2E-39 T 14-10-2018 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 SUPERFAMILY SSF55174 321 417 1.96E-24 T 14-10-2018 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 5.6E-32 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 5.6E-32 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 5.6E-32 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 5.6E-32 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 SUPERFAMILY SSF52374 2 323 1.53E-107 T 14-10-2018 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 Gene3D G3DSA:3.10.290.10 326 418 3.6E-35 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 Gene3D G3DSA:3.40.50.620 1 222 4.6E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 1.3E-87 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 Pfam PF01479 S4 domain 356 399 3.8E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 417 3.5E-139 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 46.734 T 14-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 C2I25_15995 de68037d935efc8ff7054807ff3ae6e5 418 SMART SM00363 353 414 2.4E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_07235 b4bc02df9326a30fcdbf796bd300b6f9 395 Pfam PF00999 Sodium/hydrogen exchanger family 28 390 6.5E-79 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I25_07235 b4bc02df9326a30fcdbf796bd300b6f9 395 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 32 299 9.3E-78 T 14-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 C2I25_07235 b4bc02df9326a30fcdbf796bd300b6f9 395 Gene3D G3DSA:1.20.1530.20 21 395 3.9E-105 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily C2I25_24830 47097b3e9f5c4d91b37c89de3b97f3c8 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24830 47097b3e9f5c4d91b37c89de3b97f3c8 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24830 47097b3e9f5c4d91b37c89de3b97f3c8 188 Gene3D G3DSA:1.10.357.10 1 188 9.8E-76 T 14-10-2018 C2I25_24830 47097b3e9f5c4d91b37c89de3b97f3c8 188 SUPERFAMILY SSF48498 78 186 3.56E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_24830 47097b3e9f5c4d91b37c89de3b97f3c8 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.7E-19 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24830 47097b3e9f5c4d91b37c89de3b97f3c8 188 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 56 187 1.1E-59 T 14-10-2018 IPR032551 HTH-type transcriptional repressor, C-terminal C2I25_24830 47097b3e9f5c4d91b37c89de3b97f3c8 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_24830 47097b3e9f5c4d91b37c89de3b97f3c8 188 SUPERFAMILY SSF46689 4 67 1.8E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_19970 6393c0cf65b2738ddcb179637986235b 308 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 5 300 1.8E-118 T 14-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 C2I25_19970 6393c0cf65b2738ddcb179637986235b 308 Pfam PF03419 Sporulation factor SpoIIGA 5 299 1.2E-88 T 14-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 C2I25_19970 6393c0cf65b2738ddcb179637986235b 308 PIRSF PIRSF018571 4 302 3.4E-94 T 14-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 C2I25_03965 9758b6ee3040e3ea09568835ecfde947 258 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 49 207 2.2E-10 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 C2I25_03965 9758b6ee3040e3ea09568835ecfde947 258 Gene3D G3DSA:3.60.21.10 45 226 3.6E-20 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_03965 9758b6ee3040e3ea09568835ecfde947 258 SUPERFAMILY SSF56300 45 257 3.93E-28 T 14-10-2018 C2I25_17745 538dfbcf03c53d9423f40d9e45abed0c 211 Pfam PF14062 Domain of unknown function (DUF4253) 103 204 2.4E-28 T 14-10-2018 IPR025349 Domain of unknown function DUF4253 C2I25_02990 77119b57660c77840b961ac5ea8fd20a 236 Gene3D G3DSA:2.40.30.130 1 84 1.1E-24 T 14-10-2018 C2I25_02990 77119b57660c77840b961ac5ea8fd20a 236 SMART SM00863 189 232 6.2E-14 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_02990 77119b57660c77840b961ac5ea8fd20a 236 Pfam PF01411 tRNA synthetases class II (A) 13 89 2.7E-12 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 C2I25_02990 77119b57660c77840b961ac5ea8fd20a 236 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 189 231 4.5E-13 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_02990 77119b57660c77840b961ac5ea8fd20a 236 Gene3D G3DSA:3.30.980.10 87 236 3.3E-39 T 14-10-2018 C2I25_02990 77119b57660c77840b961ac5ea8fd20a 236 SUPERFAMILY SSF55186 90 234 5.49E-40 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 C2I25_02990 77119b57660c77840b961ac5ea8fd20a 236 SUPERFAMILY SSF50447 1 73 4.94E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 SUPERFAMILY SSF51905 1 207 2.37E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.3E-12 T 14-10-2018 C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.3E-12 T 14-10-2018 C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.3E-12 T 14-10-2018 C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.3E-12 T 14-10-2018 C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 Gene3D G3DSA:3.50.50.100 1 391 6.4E-116 T 14-10-2018 C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 318 2.1E-43 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 SUPERFAMILY SSF51905 2 336 2.36E-20 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 6.5E-7 T 14-10-2018 C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 6.5E-7 T 14-10-2018 C2I25_13725 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 6.5E-7 T 14-10-2018 C2I25_19525 4c8da0756dd60ecc1918dbed15d3313c 285 SUPERFAMILY SSF56300 56 282 8.18E-37 T 14-10-2018 C2I25_19525 4c8da0756dd60ecc1918dbed15d3313c 285 Gene3D G3DSA:3.60.21.10 56 248 5.6E-26 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_19525 4c8da0756dd60ecc1918dbed15d3313c 285 Pfam PF00149 Calcineurin-like phosphoesterase 58 223 1.5E-11 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_18700 2f047bbf860fea7ddc9f81803de91166 234 Pfam PF02308 MgtC family 11 130 5.8E-37 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_18700 2f047bbf860fea7ddc9f81803de91166 234 PRINTS PR01837 MgtC/SapB protein signature 86 110 3.3E-45 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_18700 2f047bbf860fea7ddc9f81803de91166 234 PRINTS PR01837 MgtC/SapB protein signature 33 51 3.3E-45 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_18700 2f047bbf860fea7ddc9f81803de91166 234 PRINTS PR01837 MgtC/SapB protein signature 59 81 3.3E-45 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_18700 2f047bbf860fea7ddc9f81803de91166 234 PRINTS PR01837 MgtC/SapB protein signature 14 33 3.3E-45 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_18700 2f047bbf860fea7ddc9f81803de91166 234 Gene3D G3DSA:3.30.70.260 140 232 2.4E-14 T 14-10-2018 C2I25_07710 55f801514bb6e292693569ed6690b0f2 67 Pfam PF02597 ThiS family 6 67 8.6E-15 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 C2I25_07710 55f801514bb6e292693569ed6690b0f2 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 1.2E-23 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis C2I25_07710 55f801514bb6e292693569ed6690b0f2 67 Gene3D G3DSA:3.10.20.30 1 67 1.9E-20 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_07710 55f801514bb6e292693569ed6690b0f2 67 SUPERFAMILY SSF54285 3 66 1.18E-17 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp C2I25_06945 ff56915b1818567adc22ccf56aaafcc2 506 Pfam PF01943 Polysaccharide biosynthesis protein 6 300 4.0E-34 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I25_06945 ff56915b1818567adc22ccf56aaafcc2 506 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 353 494 1.1E-19 T 14-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I25_06945 ff56915b1818567adc22ccf56aaafcc2 506 PIRSF PIRSF038958 1 506 4.0E-81 T 14-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 SUPERFAMILY SSF69055 288 379 1.57E-32 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 378 7.4E-172 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 Gene3D G3DSA:1.10.1740.10 299 380 6.7E-30 T 14-10-2018 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 142 225 1.7E-42 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 SUPERFAMILY SSF51735 2 146 6.47E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 379 47.499 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 128 1.4E-41 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 Pfam PF13288 DXP reductoisomerase C-terminal domain 257 374 7.0E-45 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 Gene3D G3DSA:3.40.50.720 1 146 8.8E-49 T 14-10-2018 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 PIRSF PIRSF006205 1 380 1.0E-162 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I25_20405 6677fdcce955fe5433c0878f2709c55a 380 SUPERFAMILY SSF55347 123 260 6.87E-62 T 14-10-2018 C2I25_13935 52be69ae8458827f5fb4744d2a7c0db5 73 SMART SM00530 6 61 1.7E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_13935 52be69ae8458827f5fb4744d2a7c0db5 73 Gene3D G3DSA:1.10.260.40 2 66 1.7E-23 T 14-10-2018 C2I25_13935 52be69ae8458827f5fb4744d2a7c0db5 73 SUPERFAMILY SSF47413 1 69 7.6E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_13935 52be69ae8458827f5fb4744d2a7c0db5 73 Pfam PF01381 Helix-turn-helix 7 61 5.5E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_22950 dbcf05ab3da55e52a37bb70ea084c4c8 273 SUPERFAMILY SSF141571 53 267 5.59E-26 T 14-10-2018 C2I25_22950 dbcf05ab3da55e52a37bb70ea084c4c8 273 Pfam PF00805 Pentapeptide repeats (8 copies) 202 241 2.6E-14 T 14-10-2018 IPR001646 Pentapeptide repeat C2I25_22950 dbcf05ab3da55e52a37bb70ea084c4c8 273 Gene3D G3DSA:2.160.20.80 150 257 3.1E-20 T 14-10-2018 C2I25_00020 ddfa4273b5642481619b6156c89234a5 474 Gene3D G3DSA:3.40.605.10 25 461 2.7E-157 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_00020 ddfa4273b5642481619b6156c89234a5 474 SUPERFAMILY SSF53720 3 473 2.75E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_00020 ddfa4273b5642481619b6156c89234a5 474 Gene3D G3DSA:3.40.309.10 250 440 2.7E-157 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_00020 ddfa4273b5642481619b6156c89234a5 474 Pfam PF00171 Aldehyde dehydrogenase family 18 470 5.5E-161 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_28540 ddfa4273b5642481619b6156c89234a5 474 Gene3D G3DSA:3.40.605.10 25 461 2.7E-157 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_28540 ddfa4273b5642481619b6156c89234a5 474 SUPERFAMILY SSF53720 3 473 2.75E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_28540 ddfa4273b5642481619b6156c89234a5 474 Gene3D G3DSA:3.40.309.10 250 440 2.7E-157 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_28540 ddfa4273b5642481619b6156c89234a5 474 Pfam PF00171 Aldehyde dehydrogenase family 18 470 5.5E-161 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_28495 ddfa4273b5642481619b6156c89234a5 474 Gene3D G3DSA:3.40.605.10 25 461 2.7E-157 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_28495 ddfa4273b5642481619b6156c89234a5 474 SUPERFAMILY SSF53720 3 473 2.75E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_28495 ddfa4273b5642481619b6156c89234a5 474 Gene3D G3DSA:3.40.309.10 250 440 2.7E-157 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_28495 ddfa4273b5642481619b6156c89234a5 474 Pfam PF00171 Aldehyde dehydrogenase family 18 470 5.5E-161 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_13185 1cc51388813824b2ec0271a8f695ad59 435 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 420 1.9E-141 T 14-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 C2I25_13185 1cc51388813824b2ec0271a8f695ad59 435 PIRSF PIRSF006351 1 432 2.0E-147 T 14-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I25_13185 1cc51388813824b2ec0271a8f695ad59 435 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 420 1.9E-141 T 14-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I25_13185 1cc51388813824b2ec0271a8f695ad59 435 Pfam PF02378 Phosphotransferase system, EIIC 29 349 3.5E-64 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_27705 b9c03ef3543f0d3d6ecefa0f51f5063d 182 SMART SM01207 11 176 1.5E-48 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I25_27705 b9c03ef3543f0d3d6ecefa0f51f5063d 182 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 8 176 14.515 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I25_27705 b9c03ef3543f0d3d6ecefa0f51f5063d 182 Pfam PF02660 Glycerol-3-phosphate acyltransferase 13 178 1.0E-38 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I25_00595 5c01b06cd251964fd132e2b956b643cb 362 Gene3D G3DSA:1.25.40.10 3 358 8.1E-90 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_00595 5c01b06cd251964fd132e2b956b643cb 362 SMART SM00028 131 164 360.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00595 5c01b06cd251964fd132e2b956b643cb 362 SMART SM00028 91 124 420.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00595 5c01b06cd251964fd132e2b956b643cb 362 SMART SM00028 172 205 280.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00595 5c01b06cd251964fd132e2b956b643cb 362 SMART SM00028 212 245 11.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00595 5c01b06cd251964fd132e2b956b643cb 362 SMART SM00028 246 279 9.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_00595 5c01b06cd251964fd132e2b956b643cb 362 SUPERFAMILY SSF48452 88 284 3.48E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_22260 fb7e0aa81ec47ff8d188aa886add56f5 325 SUPERFAMILY SSF55909 38 298 6.6E-48 T 14-10-2018 C2I25_22260 fb7e0aa81ec47ff8d188aa886add56f5 325 Gene3D G3DSA:3.75.10.10 23 297 5.6E-37 T 14-10-2018 C2I25_22260 fb7e0aa81ec47ff8d188aa886add56f5 325 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 45 298 1.2E-27 T 14-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 C2I25_21165 67105e94ddc6036f29bfda10b2ce75a2 381 Pfam PF01546 Peptidase family M20/M25/M40 70 374 6.5E-33 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_21165 67105e94ddc6036f29bfda10b2ce75a2 381 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 12 364 2.9E-120 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_21165 67105e94ddc6036f29bfda10b2ce75a2 381 Gene3D G3DSA:3.30.70.360 178 292 4.4E-136 T 14-10-2018 C2I25_21165 67105e94ddc6036f29bfda10b2ce75a2 381 SUPERFAMILY SSF55031 179 287 6.28E-31 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_21165 67105e94ddc6036f29bfda10b2ce75a2 381 SUPERFAMILY SSF53187 3 377 3.71E-82 T 14-10-2018 C2I25_21165 67105e94ddc6036f29bfda10b2ce75a2 381 Gene3D G3DSA:3.40.630.10 12 362 4.4E-136 T 14-10-2018 C2I25_21165 67105e94ddc6036f29bfda10b2ce75a2 381 Pfam PF07687 Peptidase dimerisation domain 179 274 6.7E-13 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_21165 67105e94ddc6036f29bfda10b2ce75a2 381 PIRSF PIRSF005962 1 380 2.9E-129 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_09770 7b0f9643e64c3c763a143ce1c4f5f789 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.4E-22 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 C2I25_09770 7b0f9643e64c3c763a143ce1c4f5f789 96 Gene3D G3DSA:1.10.20.60 2 94 6.6E-32 T 14-10-2018 C2I25_09770 7b0f9643e64c3c763a143ce1c4f5f789 96 SUPERFAMILY SSF141000 4 94 5.62E-32 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 C2I25_09770 7b0f9643e64c3c763a143ce1c4f5f789 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 5.1E-33 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 C2I25_09770 7b0f9643e64c3c763a143ce1c4f5f789 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 25.744 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 C2I25_13205 0134a2353806c0058f967a23d63d0923 393 TIGRFAM TIGR00937 2A51: chromate efflux transporter 19 387 1.0E-141 T 14-10-2018 IPR014047 Chromate transporter, long chain C2I25_13205 0134a2353806c0058f967a23d63d0923 393 Pfam PF02417 Chromate transporter 12 177 1.9E-35 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 C2I25_13205 0134a2353806c0058f967a23d63d0923 393 Pfam PF02417 Chromate transporter 225 386 8.0E-41 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 C2I25_13205 0134a2353806c0058f967a23d63d0923 393 PIRSF PIRSF004810 2 393 7.0E-128 T 14-10-2018 IPR014047 Chromate transporter, long chain C2I25_20845 252e81e23c9c5acb904681746d8ca84e 340 Gene3D G3DSA:1.10.3470.10 7 340 1.8E-94 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_20845 252e81e23c9c5acb904681746d8ca84e 340 Pfam PF01032 FecCD transport family 19 337 3.1E-86 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_20845 252e81e23c9c5acb904681746d8ca84e 340 SUPERFAMILY SSF81345 7 337 7.45E-77 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_21720 3ed86d4fc3ac29f51104ef6a87dc7e52 114 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 4 111 7.9E-35 T 14-10-2018 IPR018745 Domain of unknown function DUF2294 C2I25_09470 ff2af079466ea3790c4350651e0dd0fa 229 SMART SM00100 15 133 1.5E-4 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_09470 ff2af079466ea3790c4350651e0dd0fa 229 SMART SM00419 172 220 5.8E-7 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I25_09470 ff2af079466ea3790c4350651e0dd0fa 229 Pfam PF13545 Crp-like helix-turn-helix domain 154 226 1.2E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I25_09470 ff2af079466ea3790c4350651e0dd0fa 229 Gene3D G3DSA:1.10.10.10 138 227 4.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_09470 ff2af079466ea3790c4350651e0dd0fa 229 Gene3D G3DSA:2.60.120.10 2 137 7.3E-24 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_09470 ff2af079466ea3790c4350651e0dd0fa 229 SUPERFAMILY SSF46785 150 227 2.94E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_09470 ff2af079466ea3790c4350651e0dd0fa 229 Pfam PF00027 Cyclic nucleotide-binding domain 34 120 6.2E-13 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_09470 ff2af079466ea3790c4350651e0dd0fa 229 SUPERFAMILY SSF51206 23 147 6.15E-32 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like C2I25_17205 38681ae87e8bf35c1045999744d003ec 519 PIRSF PIRSF038958 1 517 3.9E-175 T 14-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I25_17205 38681ae87e8bf35c1045999744d003ec 519 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 494 2.8E-197 T 14-10-2018 IPR014249 Sporulation stage V protein B C2I25_17205 38681ae87e8bf35c1045999744d003ec 519 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 359 500 3.8E-17 T 14-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I25_17205 38681ae87e8bf35c1045999744d003ec 519 Pfam PF01943 Polysaccharide biosynthesis protein 6 308 1.1E-53 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I25_07960 ceb4ad27366c9ec7589d1d125cf5eca6 391 Pfam PF07687 Peptidase dimerisation domain 186 281 1.8E-13 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I25_07960 ceb4ad27366c9ec7589d1d125cf5eca6 391 SUPERFAMILY SSF55031 184 295 1.31E-29 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I25_07960 ceb4ad27366c9ec7589d1d125cf5eca6 391 SUPERFAMILY SSF53187 11 388 4.86E-82 T 14-10-2018 C2I25_07960 ceb4ad27366c9ec7589d1d125cf5eca6 391 Gene3D G3DSA:3.40.630.10 14 372 2.6E-138 T 14-10-2018 C2I25_07960 ceb4ad27366c9ec7589d1d125cf5eca6 391 Pfam PF01546 Peptidase family M20/M25/M40 72 385 2.8E-32 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I25_07960 ceb4ad27366c9ec7589d1d125cf5eca6 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 375 4.7E-115 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_07960 ceb4ad27366c9ec7589d1d125cf5eca6 391 PIRSF PIRSF005962 4 391 2.2E-134 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I25_07960 ceb4ad27366c9ec7589d1d125cf5eca6 391 Gene3D G3DSA:3.30.70.360 181 295 2.6E-138 T 14-10-2018 C2I25_03800 e717697bdb1d4fac9bb3a3c5421af501 178 PIRSF PIRSF007165 1 178 5.0E-83 T 14-10-2018 IPR011188 Uncharacterised protein family UPF0302 C2I25_03800 e717697bdb1d4fac9bb3a3c5421af501 178 Pfam PF08858 IDEAL domain 139 175 2.9E-16 T 14-10-2018 IPR014957 IDEAL domain C2I25_03800 e717697bdb1d4fac9bb3a3c5421af501 178 Gene3D G3DSA:1.20.1440.290 1 123 2.4E-56 T 14-10-2018 IPR038091 UPF0302, N-terminal domain superfamily C2I25_03800 e717697bdb1d4fac9bb3a3c5421af501 178 SMART SM00914 139 175 1.7E-14 T 14-10-2018 IPR014957 IDEAL domain C2I25_03800 e717697bdb1d4fac9bb3a3c5421af501 178 Pfam PF08864 UPF0302 domain 9 113 5.7E-47 T 14-10-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal C2I25_03800 e717697bdb1d4fac9bb3a3c5421af501 178 Hamap MF_00760 UPF0302 protein . 2 178 33.36 T 14-10-2018 IPR011188 Uncharacterised protein family UPF0302 C2I25_03800 e717697bdb1d4fac9bb3a3c5421af501 178 Gene3D G3DSA:4.10.810.10 124 178 1.9E-26 T 14-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 SUPERFAMILY SSF102114 119 365 4.97E-57 T 14-10-2018 C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 SMART SM00729 143 361 6.9E-59 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 Gene3D G3DSA:3.80.30.20 140 374 6.0E-85 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 429 2.5E-149 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 Pfam PF04055 Radical SAM superfamily 149 319 3.3E-27 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 Pfam PF01938 TRAM domain 391 427 3.4E-6 T 14-10-2018 IPR002792 TRAM domain C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 Gene3D G3DSA:3.40.50.12160 3 134 4.2E-26 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 1.0E-140 T 14-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 C2I25_17725 d50d79a91a2bda09935d205c6b9714fc 450 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 7.1E-27 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 C2I25_07530 8ea7d1c2e0d6acdf3d20e6773e7a64c7 82 Pfam PF14148 YhdB-like protein 3 71 7.6E-38 T 14-10-2018 IPR025431 YhdB-like protein C2I25_06495 51f68bed25ca9931e566246d8050575c 577 Pfam PF00395 S-layer homology domain 35 77 1.1E-9 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06495 51f68bed25ca9931e566246d8050575c 577 Pfam PF00395 S-layer homology domain 171 214 4.5E-9 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06495 51f68bed25ca9931e566246d8050575c 577 Pfam PF00395 S-layer homology domain 111 155 1.5E-8 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06495 51f68bed25ca9931e566246d8050575c 577 Gene3D G3DSA:3.10.620.30 303 441 6.2E-22 T 14-10-2018 C2I25_06495 51f68bed25ca9931e566246d8050575c 577 Pfam PF01841 Transglutaminase-like superfamily 329 423 2.1E-14 T 14-10-2018 IPR002931 Transglutaminase-like C2I25_06495 51f68bed25ca9931e566246d8050575c 577 SUPERFAMILY SSF54001 319 475 1.47E-26 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_06495 51f68bed25ca9931e566246d8050575c 577 SMART SM00460 370 426 1.1E-8 T 14-10-2018 IPR002931 Transglutaminase-like C2I25_15125 39bdbd1e81ccd2443aeec7600ab49725 206 Pfam PF04203 Sortase family 78 200 7.0E-27 T 14-10-2018 IPR005754 Sortase family C2I25_15125 39bdbd1e81ccd2443aeec7600ab49725 206 Gene3D G3DSA:2.40.260.10 61 206 4.7E-44 T 14-10-2018 IPR023365 Sortase domain superfamily C2I25_15125 39bdbd1e81ccd2443aeec7600ab49725 206 TIGRFAM TIGR01076 sortase_fam: sortase 77 199 6.9E-23 T 14-10-2018 IPR005754 Sortase family C2I25_15125 39bdbd1e81ccd2443aeec7600ab49725 206 SUPERFAMILY SSF63817 58 201 6.15E-34 T 14-10-2018 IPR023365 Sortase domain superfamily C2I25_02555 8db48f2f5f168c9fc267bfd6ba6f0348 306 Pfam PF13781 DoxX-like family 180 280 1.1E-25 T 14-10-2018 IPR025695 DoxX-like family C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 Gene3D G3DSA:1.20.58.1830 3 31 3.6E-52 T 14-10-2018 C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 Gene3D G3DSA:1.20.1330.10 43 174 3.6E-52 T 14-10-2018 C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 5.4E-35 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 Gene3D G3DSA:1.10.8.410 219 273 4.3E-21 T 14-10-2018 C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 PRINTS PR00207 Flagellin signature 109 132 5.5E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 PRINTS PR00207 Flagellin signature 35 52 5.5E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 PRINTS PR00207 Flagellin signature 74 93 5.5E-19 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 SUPERFAMILY SSF64518 1 273 3.27E-82 T 14-10-2018 C2I25_03065 0f0d566fffc8192006f56bb1b6140d7d 273 Pfam PF00700 Bacterial flagellin C-terminal helical region 187 272 3.1E-24 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I25_24660 40ed0897a50017f7df0c6f873e3ac012 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 119 2.4E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_24660 40ed0897a50017f7df0c6f873e3ac012 139 SUPERFAMILY SSF54593 1 124 2.69E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24660 40ed0897a50017f7df0c6f873e3ac012 139 Gene3D G3DSA:3.10.180.10 2 121 2.0E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 ProSitePatterns PS00042 Crp-type HTH domain signature. 169 192 - T 14-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 SUPERFAMILY SSF46785 140 223 8.65E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 SMART SM00100 3 122 5.3E-10 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 Gene3D G3DSA:1.10.10.10 139 226 1.0E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 SMART SM00419 161 209 1.5E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 SUPERFAMILY SSF51206 9 137 1.03E-30 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 167 183 3.2E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 183 198 3.2E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 Pfam PF13545 Crp-like helix-turn-helix domain 144 213 1.6E-17 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 Gene3D G3DSA:2.60.120.10 6 138 5.4E-30 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_01035 6069fcb60ad0edfcfc46ffe4e75be47c 230 Pfam PF00027 Cyclic nucleotide-binding domain 23 109 1.4E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_25120 74e9b163afc7cd424ebfe08842dae8ce 261 SUPERFAMILY SSF53335 29 256 3.62E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_25120 74e9b163afc7cd424ebfe08842dae8ce 261 Gene3D G3DSA:3.40.50.150 27 261 7.2E-61 T 14-10-2018 C2I25_25120 74e9b163afc7cd424ebfe08842dae8ce 261 Pfam PF08241 Methyltransferase domain 46 142 1.7E-21 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 SMART SM00448 3 115 2.3E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 Pfam PF00072 Response regulator receiver domain 5 116 1.5E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 SMART SM00421 149 206 1.7E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 SUPERFAMILY SSF52172 1 131 1.21E-32 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.9E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.9E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.9E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 Gene3D G3DSA:3.40.50.12740 3 211 3.5E-60 T 14-10-2018 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 SUPERFAMILY SSF46894 150 207 8.5E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_02655 a54fe72090972dd3e47ce898243bf977 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 205 2.4E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_01100 fc863783b13bad72f43f27ebf1e46c3a 192 Gene3D G3DSA:1.10.1740.10 3 91 1.7E-18 T 14-10-2018 C2I25_01100 fc863783b13bad72f43f27ebf1e46c3a 192 SUPERFAMILY SSF88946 4 98 1.46E-21 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_01100 fc863783b13bad72f43f27ebf1e46c3a 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 177 1.2E-27 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I25_01100 fc863783b13bad72f43f27ebf1e46c3a 192 Pfam PF04542 Sigma-70 region 2 30 91 2.6E-11 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_01100 fc863783b13bad72f43f27ebf1e46c3a 192 SUPERFAMILY SSF88659 113 176 1.87E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_01100 fc863783b13bad72f43f27ebf1e46c3a 192 Gene3D G3DSA:1.10.10.10 120 181 6.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01100 fc863783b13bad72f43f27ebf1e46c3a 192 Pfam PF08281 Sigma-70, region 4 122 174 3.0E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I25_11630 91f78524cce2563ab6ba3a3491909e26 375 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 14-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 C2I25_11630 91f78524cce2563ab6ba3a3491909e26 375 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 375 105.165 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 C2I25_11630 91f78524cce2563ab6ba3a3491909e26 375 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 366 1.5E-132 T 14-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 C2I25_11630 91f78524cce2563ab6ba3a3491909e26 375 Gene3D G3DSA:1.20.1050.90 119 311 1.3E-113 T 14-10-2018 C2I25_11630 91f78524cce2563ab6ba3a3491909e26 375 SUPERFAMILY SSF52540 2 352 6.37E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11630 91f78524cce2563ab6ba3a3491909e26 375 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 348 1.2E-20 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal C2I25_11630 91f78524cce2563ab6ba3a3491909e26 375 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 14-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 C2I25_11630 91f78524cce2563ab6ba3a3491909e26 375 Gene3D G3DSA:3.40.50.300 6 345 1.3E-113 T 14-10-2018 C2I25_25860 bd9a24e17a1ebcfe1868e55e1876eafc 178 Gene3D G3DSA:3.30.70.1280 1 88 1.2E-31 T 14-10-2018 C2I25_25860 bd9a24e17a1ebcfe1868e55e1876eafc 178 SUPERFAMILY SSF160379 1 175 7.45E-51 T 14-10-2018 C2I25_25860 bd9a24e17a1ebcfe1868e55e1876eafc 178 Pfam PF08002 Protein of unknown function (DUF1697) 1 137 1.3E-43 T 14-10-2018 IPR012545 Protein of unknown function DUF1697 C2I25_25860 bd9a24e17a1ebcfe1868e55e1876eafc 178 PIRSF PIRSF008502 1 178 7.4E-63 T 14-10-2018 IPR012545 Protein of unknown function DUF1697 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 Pfam PF01751 Toprim domain 5 134 1.7E-16 T 14-10-2018 IPR006171 TOPRIM domain C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 299 314 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 SMART SM00437 262 549 2.0E-83 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 Gene3D G3DSA:1.10.460.10 160 593 5.2E-146 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 3.8E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 512 526 3.8E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 3.8E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 3.8E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 305 314 3.8E-25 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 SMART SM00493 3 126 3.7E-18 T 14-10-2018 IPR006171 TOPRIM domain C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 SMART SM00436 126 216 1.1E-35 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 727 2.8E-260 T 14-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 Gene3D G3DSA:1.10.290.10 271 401 5.2E-146 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 Gene3D G3DSA:3.40.50.140 3 154 3.6E-54 T 14-10-2018 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 638 72.057 T 14-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 Pfam PF01131 DNA topoisomerase 152 583 1.3E-116 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 Gene3D G3DSA:2.70.20.10 210 477 5.2E-146 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 C2I25_09435 6b9dd4cf03d4b158bc546c8e5f2fe5a1 729 SUPERFAMILY SSF56712 3 598 7.72E-176 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain C2I25_18870 febae4d1e936dbed789069535de4cd73 269 Pfam PF13847 Methyltransferase domain 44 170 5.3E-24 T 14-10-2018 IPR025714 Methyltransferase domain C2I25_18870 febae4d1e936dbed789069535de4cd73 269 Gene3D G3DSA:3.40.50.150 6 230 1.6E-48 T 14-10-2018 C2I25_18870 febae4d1e936dbed789069535de4cd73 269 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 10 265 1.1E-81 T 14-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 C2I25_18870 febae4d1e936dbed789069535de4cd73 269 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 2 265 30.14 T 14-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 C2I25_18870 febae4d1e936dbed789069535de4cd73 269 SUPERFAMILY SSF53335 10 188 3.19E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_05110 a62c5d238cd95a14073c156711fcd26e 69 SMART SM00530 4 59 2.6E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_05110 a62c5d238cd95a14073c156711fcd26e 69 SUPERFAMILY SSF47413 2 63 3.22E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_05110 a62c5d238cd95a14073c156711fcd26e 69 Pfam PF01381 Helix-turn-helix 7 57 1.5E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_05110 a62c5d238cd95a14073c156711fcd26e 69 Gene3D G3DSA:1.10.260.40 1 65 7.3E-27 T 14-10-2018 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 145 2.8E-25 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 71.632 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 1.0E-28 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 1.0E-28 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 1.0E-28 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 1.0E-28 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 SUPERFAMILY SSF55252 80 149 4.32E-22 T 14-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 SUPERFAMILY SSF46785 5 78 6.81E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 1.8E-52 T 14-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 Gene3D G3DSA:3.30.1360.40 68 149 9.3E-31 T 14-10-2018 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 7.2E-31 T 14-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 5.0E-31 T 14-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 C2I25_18445 23ece76d112e7fb5e0ff539bfedfad21 149 Gene3D G3DSA:1.10.10.10 4 67 9.0E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20245 c629d0ff4487abdf7286124eb7ad70a9 330 Pfam PF02504 Fatty acid synthesis protein 1 317 1.4E-128 T 14-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 C2I25_20245 c629d0ff4487abdf7286124eb7ad70a9 330 PIRSF PIRSF002465 1 330 2.1E-131 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 C2I25_20245 c629d0ff4487abdf7286124eb7ad70a9 330 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 330 154.446 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 C2I25_20245 c629d0ff4487abdf7286124eb7ad70a9 330 Gene3D G3DSA:3.40.718.10 1 330 2.9E-139 T 14-10-2018 C2I25_20245 c629d0ff4487abdf7286124eb7ad70a9 330 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 326 3.6E-136 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 C2I25_20245 c629d0ff4487abdf7286124eb7ad70a9 330 SUPERFAMILY SSF53659 1 326 2.71E-107 T 14-10-2018 C2I25_02425 cb4e0f5f57321fab741746de675f4892 299 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 7 287 7.8E-104 T 14-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 C2I25_02425 cb4e0f5f57321fab741746de675f4892 299 Gene3D G3DSA:3.20.10.10 127 288 5.5E-59 T 14-10-2018 C2I25_02425 cb4e0f5f57321fab741746de675f4892 299 Gene3D G3DSA:3.30.470.10 1 126 8.9E-47 T 14-10-2018 C2I25_02425 cb4e0f5f57321fab741746de675f4892 299 SUPERFAMILY SSF56752 3 286 4.45E-93 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 C2I25_02425 cb4e0f5f57321fab741746de675f4892 299 Pfam PF01063 Amino-transferase class IV 32 258 5.1E-58 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 C2I25_02425 cb4e0f5f57321fab741746de675f4892 299 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 C2I25_17850 4204838f45116c8e9d07d60338e94efc 250 Pfam PF14181 YqfQ-like protein 35 250 3.2E-51 T 14-10-2018 IPR025571 YqfQ-like protein C2I25_17985 0611054d4fb106d676d3333f0c3b80cb 209 Gene3D G3DSA:3.60.15.10 1 209 5.5E-64 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_17985 0611054d4fb106d676d3333f0c3b80cb 209 SMART SM00849 12 192 5.9E-42 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_17985 0611054d4fb106d676d3333f0c3b80cb 209 Pfam PF00753 Metallo-beta-lactamase superfamily 9 192 2.4E-31 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_17985 0611054d4fb106d676d3333f0c3b80cb 209 SUPERFAMILY SSF56281 1 209 1.97E-53 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_24970 375125ffc5a36970124f8a7d4e4f6abe 282 SUPERFAMILY SSF161098 76 255 5.63E-29 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_24970 375125ffc5a36970124f8a7d4e4f6abe 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 267 1.1E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_24970 375125ffc5a36970124f8a7d4e4f6abe 282 Gene3D G3DSA:1.10.3720.10 75 264 2.2E-20 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 PRINTS PR00116 Arginase signature 123 138 2.4E-10 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 PRINTS PR00116 Arginase signature 238 267 2.4E-10 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 PRINTS PR00116 Arginase signature 273 287 2.4E-10 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 Gene3D G3DSA:3.40.800.10 22 316 3.0E-93 T 14-10-2018 C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 Pfam PF00491 Arginase family 37 311 1.6E-71 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 311 4.0E-85 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 ProSitePatterns PS01053 Arginase family signature. 241 262 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 SUPERFAMILY SSF52768 29 313 2.34E-74 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily C2I25_21240 c1567726da9882d8cfd2b68a61a455e3 323 PIRSF PIRSF036979 10 317 1.3E-60 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I25_00600 b2b26010bdb31cd3e0a42841e229aa3e 352 Pfam PF08239 Bacterial SH3 domain 220 255 8.2E-7 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_00600 b2b26010bdb31cd3e0a42841e229aa3e 352 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 49 167 3.0E-12 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_00600 b2b26010bdb31cd3e0a42841e229aa3e 352 SUPERFAMILY SSF55846 34 186 3.6E-33 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_00600 b2b26010bdb31cd3e0a42841e229aa3e 352 Gene3D G3DSA:3.40.80.10 22 202 3.9E-54 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_00600 b2b26010bdb31cd3e0a42841e229aa3e 352 SMART SM00644 34 168 4.0E-23 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_00600 b2b26010bdb31cd3e0a42841e229aa3e 352 Gene3D G3DSA:2.30.30.40 218 276 6.3E-9 T 14-10-2018 C2I25_24485 c0d53e403f7bfe5a44addf9cff901828 309 SUPERFAMILY SSF52540 4 273 4.4E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24485 c0d53e403f7bfe5a44addf9cff901828 309 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 32 162 4.4E-62 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 C2I25_24485 c0d53e403f7bfe5a44addf9cff901828 309 Gene3D G3DSA:1.10.8.300 193 300 7.7E-31 T 14-10-2018 C2I25_24485 c0d53e403f7bfe5a44addf9cff901828 309 Gene3D G3DSA:3.40.50.300 13 179 2.6E-46 T 14-10-2018 C2I25_24485 c0d53e403f7bfe5a44addf9cff901828 309 PIRSF PIRSF002849 1 305 3.2E-124 T 14-10-2018 C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 Pfam PF00717 Peptidase S24-like 127 191 6.8E-17 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 Pfam PF01726 LexA DNA binding domain 5 69 1.3E-30 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 Hamap MF_00015 LexA repressor [lexA]. 7 209 35.671 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 SUPERFAMILY SSF51306 86 208 4.36E-36 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 Gene3D G3DSA:1.10.10.10 7 72 3.1E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 Gene3D G3DSA:2.10.109.10 92 209 1.7E-41 T 14-10-2018 C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 SUPERFAMILY SSF46785 7 74 2.16E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 TIGRFAM TIGR00498 lexA: repressor LexA 5 209 2.7E-79 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 124 134 2.8E-12 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 164 176 2.8E-12 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 C2I25_21030 c9f751cbefa2f7754fc6f5ba0b90b6de 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 135 146 2.8E-12 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 C2I25_00575 cdaf3151b5c1adecfd3628ca2972ea57 96 Gene3D G3DSA:1.10.10.60 10 94 5.7E-12 T 14-10-2018 C2I25_00575 cdaf3151b5c1adecfd3628ca2972ea57 96 Pfam PF01527 Transposase 6 87 4.3E-12 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 C2I25_00575 cdaf3151b5c1adecfd3628ca2972ea57 96 SUPERFAMILY SSF46689 6 94 1.25E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 Gene3D G3DSA:2.160.10.10 240 373 2.1E-20 T 14-10-2018 C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 SUPERFAMILY SSF53738 387 516 3.88E-6 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 Gene3D G3DSA:3.90.550.10 1 239 6.6E-71 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 297 2.0E-5 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 Gene3D G3DSA:3.40.120.10 383 524 1.3E-14 T 14-10-2018 C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 SUPERFAMILY SSF53448 1 278 1.08E-75 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 SUPERFAMILY SSF51161 199 370 3.47E-27 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 393 507 1.7E-8 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I25_17955 53d70366f99cee00adbf16788ba78c2f 784 Pfam PF00483 Nucleotidyl transferase 2 230 6.2E-50 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_14325 bec66c911db89e1ac026a9429ad933de 448 Pfam PF15609 Phosphoribosyl transferase 42 257 1.0E-74 T 14-10-2018 C2I25_14325 bec66c911db89e1ac026a9429ad933de 448 SUPERFAMILY SSF53271 114 239 8.38E-8 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_14325 bec66c911db89e1ac026a9429ad933de 448 Gene3D G3DSA:3.40.50.2020 45 258 1.4E-6 T 14-10-2018 C2I25_14325 bec66c911db89e1ac026a9429ad933de 448 PIRSF PIRSF020967 13 93 2.5E-12 T 14-10-2018 IPR011214 Uncharacterised conserved protein UCP020967 C2I25_14325 bec66c911db89e1ac026a9429ad933de 448 PIRSF PIRSF020967 114 441 7.7E-37 T 14-10-2018 IPR011214 Uncharacterised conserved protein UCP020967 C2I25_14325 bec66c911db89e1ac026a9429ad933de 448 Pfam PF12500 TRSP domain C terminus to PRTase_2 302 428 7.4E-39 T 14-10-2018 IPR022537 TRSP domain C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 PIRSF PIRSF004491 2 317 9.0E-106 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 SUPERFAMILY SSF52374 19 178 8.16E-29 T 14-10-2018 C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 Pfam PF06574 FAD synthetase 18 169 1.3E-47 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 SUPERFAMILY SSF82114 176 314 4.58E-47 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 Gene3D G3DSA:2.40.30.30 188 323 5.8E-45 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 310 1.9E-95 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 Gene3D G3DSA:3.40.50.620 5 187 1.6E-52 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 SMART SM00904 185 311 8.5E-62 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 C2I25_20470 221a4a9c58a3b0258985dcf2019c685c 323 Pfam PF01687 Riboflavin kinase 186 310 2.3E-38 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 C2I25_07410 1d4fec8495e9aa26a2f505d2627c9175 331 Gene3D G3DSA:3.40.50.720 131 299 2.1E-120 T 14-10-2018 C2I25_07410 1d4fec8495e9aa26a2f505d2627c9175 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 7 331 1.4E-141 T 14-10-2018 IPR014188 Acrylyl-CoA reductase AcuI C2I25_07410 1d4fec8495e9aa26a2f505d2627c9175 331 SUPERFAMILY SSF50129 6 150 2.13E-42 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_07410 1d4fec8495e9aa26a2f505d2627c9175 331 SUPERFAMILY SSF51735 121 294 2.83E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_07410 1d4fec8495e9aa26a2f505d2627c9175 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 92 1.1E-5 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_07410 1d4fec8495e9aa26a2f505d2627c9175 331 Pfam PF00107 Zinc-binding dehydrogenase 164 277 3.4E-17 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_07410 1d4fec8495e9aa26a2f505d2627c9175 331 Gene3D G3DSA:3.90.180.10 23 330 2.1E-120 T 14-10-2018 C2I25_07410 1d4fec8495e9aa26a2f505d2627c9175 331 SMART SM00829 12 329 4.4E-8 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_25615 bf52abeaacd889f4cf5c970ca7fc540b 220 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 220 32.398 T 14-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 C2I25_25615 bf52abeaacd889f4cf5c970ca7fc540b 220 Gene3D G3DSA:3.40.50.1360 4 216 1.1E-83 T 14-10-2018 C2I25_25615 bf52abeaacd889f4cf5c970ca7fc540b 220 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 3 217 7.0E-91 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 C2I25_25615 bf52abeaacd889f4cf5c970ca7fc540b 220 Gene3D G3DSA:3.30.70.260 124 200 1.1E-83 T 14-10-2018 C2I25_25615 bf52abeaacd889f4cf5c970ca7fc540b 220 SUPERFAMILY SSF100950 2 143 2.69E-45 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_25615 bf52abeaacd889f4cf5c970ca7fc540b 220 SUPERFAMILY SSF75445 125 203 9.29E-24 T 14-10-2018 C2I25_25615 bf52abeaacd889f4cf5c970ca7fc540b 220 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 216 1.6E-69 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 C2I25_08970 788f5d32728b62f5eccf309e56b2a511 86 Pfam PF14182 YgaB-like protein 3 78 5.4E-30 T 14-10-2018 IPR025572 YgaB-like protein C2I25_22630 f1d7528c9e082ea70a8f26ec0402cf25 596 SUPERFAMILY SSF52402 208 551 8.38E-32 T 14-10-2018 C2I25_22630 f1d7528c9e082ea70a8f26ec0402cf25 596 PIRSF PIRSF001589 72 595 1.4E-51 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I25_22630 f1d7528c9e082ea70a8f26ec0402cf25 596 SUPERFAMILY SSF56235 59 213 1.37E-18 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_22630 f1d7528c9e082ea70a8f26ec0402cf25 596 Pfam PF00733 Asparagine synthase 232 586 3.5E-34 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 C2I25_22630 f1d7528c9e082ea70a8f26ec0402cf25 596 Pfam PF13537 Glutamine amidotransferase domain 73 153 5.0E-14 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I25_22630 f1d7528c9e082ea70a8f26ec0402cf25 596 Gene3D G3DSA:3.60.20.10 29 212 7.5E-22 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_13875 8779a02bab24dcce504b3f2a919fdee4 563 Pfam PF00672 HAMP domain 205 254 7.4E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_13875 8779a02bab24dcce504b3f2a919fdee4 563 Gene3D G3DSA:1.20.1480.50 158 258 3.2E-13 T 14-10-2018 C2I25_13875 8779a02bab24dcce504b3f2a919fdee4 563 SMART SM00283 286 561 4.4E-81 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_13875 8779a02bab24dcce504b3f2a919fdee4 563 SMART SM00304 203 257 1.3E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_13875 8779a02bab24dcce504b3f2a919fdee4 563 SUPERFAMILY SSF58104 225 561 1.27E-75 T 14-10-2018 C2I25_13875 8779a02bab24dcce504b3f2a919fdee4 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 514 4.2E-47 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_13875 8779a02bab24dcce504b3f2a919fdee4 563 Gene3D G3DSA:1.10.287.950 259 561 1.1E-68 T 14-10-2018 C2I25_19405 959a47309cdcafedfda009a8cf79cd9d 558 SMART SM00642 13 419 2.7E-170 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_19405 959a47309cdcafedfda009a8cf79cd9d 558 Gene3D G3DSA:2.60.40.1180 481 558 3.3E-24 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_19405 959a47309cdcafedfda009a8cf79cd9d 558 Gene3D G3DSA:3.20.20.80 4 472 2.9E-220 T 14-10-2018 C2I25_19405 959a47309cdcafedfda009a8cf79cd9d 558 Pfam PF00128 Alpha amylase, catalytic domain 28 376 1.8E-135 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_19405 959a47309cdcafedfda009a8cf79cd9d 558 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 553 2.0E-9 T 14-10-2018 IPR032091 Maltogenic Amylase, C-terminal C2I25_19405 959a47309cdcafedfda009a8cf79cd9d 558 SUPERFAMILY SSF51011 480 557 2.88E-21 T 14-10-2018 C2I25_19405 959a47309cdcafedfda009a8cf79cd9d 558 Gene3D G3DSA:3.90.400.10 105 174 2.9E-220 T 14-10-2018 C2I25_19405 959a47309cdcafedfda009a8cf79cd9d 558 SUPERFAMILY SSF51445 3 475 2.11E-163 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_27980 2efbbab3f0fe93373f199497ed45bcb9 60 Pfam PF13213 Protein of unknown function (DUF4021) 9 51 1.5E-25 T 14-10-2018 IPR025094 Protein of unknown function DUF4021 C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 5.8E-107 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 Pfam PF00574 Clp protease 13 192 4.6E-87 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.6E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.6E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.6E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.6E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.6E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 14-10-2018 IPR018215 ClpP, Ser active site C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 14-10-2018 IPR033135 ClpP, histidine active site C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 SUPERFAMILY SSF52096 10 192 7.02E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.238 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_13470 b81d37ad1baf6afe8a68d4582d88540c 193 Gene3D G3DSA:3.90.226.10 1 193 6.1E-84 T 14-10-2018 C2I25_07075 2fe857257e462aef6abd8bd01745a83d 666 SMART SM00382 453 641 1.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_07075 2fe857257e462aef6abd8bd01745a83d 666 Gene3D G3DSA:1.20.1560.10 125 412 3.5E-71 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_07075 2fe857257e462aef6abd8bd01745a83d 666 Gene3D G3DSA:3.40.50.300 424 666 6.6E-83 T 14-10-2018 C2I25_07075 2fe857257e462aef6abd8bd01745a83d 666 Pfam PF00005 ABC transporter 444 589 9.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_07075 2fe857257e462aef6abd8bd01745a83d 666 SUPERFAMILY SSF90123 5 414 6.02E-72 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_07075 2fe857257e462aef6abd8bd01745a83d 666 Pfam PF00664 ABC transporter transmembrane region 149 384 8.2E-40 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_07075 2fe857257e462aef6abd8bd01745a83d 666 SUPERFAMILY SSF52540 421 660 6.2E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23640 faa3fb847fdc4d32560dda30079f0c8d 142 ProDom PD049095 YRZH 103 141 2.0E-16 T 14-10-2018 C2I25_23640 faa3fb847fdc4d32560dda30079f0c8d 142 Pfam PF17428 Family of unknown function (DUF5412) 13 129 2.2E-43 T 14-10-2018 IPR035406 Protein of unknown function DUF5412 C2I25_00200 73b97b1bf00a44600f97e7485e53d2da 119 SUPERFAMILY SSF55729 7 115 1.74E-12 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_00200 73b97b1bf00a44600f97e7485e53d2da 119 Pfam PF13673 Acetyltransferase (GNAT) domain 11 117 9.5E-7 T 14-10-2018 IPR000182 GNAT domain C2I25_00200 73b97b1bf00a44600f97e7485e53d2da 119 Gene3D G3DSA:3.40.630.30 3 117 1.8E-11 T 14-10-2018 C2I25_26455 f55a657364188a1337d53bb8ee3e7008 51 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 47 1.9E-15 T 14-10-2018 IPR011437 Domain of unknown function DUF1540 C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 SUPERFAMILY SSF57863 80 231 2.07E-45 T 14-10-2018 IPR037278 ARFGAP/RecO-like zinc finger C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 Gene3D G3DSA:1.20.1440.120 88 225 1.6E-17 T 14-10-2018 C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 Pfam PF11967 Recombination protein O N terminal 1 77 5.4E-26 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 Gene3D G3DSA:3.30.60.100 146 185 1.6E-17 T 14-10-2018 C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 Gene3D G3DSA:2.40.50.140 2 81 5.2E-16 T 14-10-2018 C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 243 5.9E-76 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 Pfam PF02565 Recombination protein O C terminal 82 238 3.9E-34 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 28.869 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 C2I25_17795 dce0045a35f9b56a8a3796e2f8b65d4e 248 SUPERFAMILY SSF50249 1 77 1.11E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_12020 b53b316999aee32535a6f2e8bacfe1ad 484 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 138 285 3.3E-11 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like C2I25_01550 4be2d6967fab385b7d5f3ba114d44176 147 ProSitePatterns PS00818 Dps protein family signature 1. 29 45 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 C2I25_01550 4be2d6967fab385b7d5f3ba114d44176 147 Pfam PF00210 Ferritin-like domain 9 146 5.1E-36 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 C2I25_01550 4be2d6967fab385b7d5f3ba114d44176 147 SUPERFAMILY SSF47240 7 146 7.65E-49 T 14-10-2018 IPR009078 Ferritin-like superfamily C2I25_01550 4be2d6967fab385b7d5f3ba114d44176 147 Gene3D G3DSA:1.20.1260.10 2 147 5.9E-58 T 14-10-2018 IPR012347 Ferritin-like C2I25_01550 4be2d6967fab385b7d5f3ba114d44176 147 PIRSF PIRSF005900 1 147 1.1E-51 T 14-10-2018 IPR002177 DNA-binding protein Dps C2I25_01550 4be2d6967fab385b7d5f3ba114d44176 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 124 142 1.5E-13 T 14-10-2018 IPR002177 DNA-binding protein Dps C2I25_01550 4be2d6967fab385b7d5f3ba114d44176 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 29 45 1.5E-13 T 14-10-2018 IPR002177 DNA-binding protein Dps C2I25_01550 4be2d6967fab385b7d5f3ba114d44176 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 53 69 1.5E-13 T 14-10-2018 IPR002177 DNA-binding protein Dps C2I25_07435 4b1ef6c6fa0774679f7628b544e011f6 98 SUPERFAMILY SSF52821 2 94 2.75E-28 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_07435 4b1ef6c6fa0774679f7628b544e011f6 98 Gene3D G3DSA:3.40.250.10 1 98 8.2E-29 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_07435 4b1ef6c6fa0774679f7628b544e011f6 98 SMART SM00450 5 97 1.2E-17 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_07435 4b1ef6c6fa0774679f7628b544e011f6 98 Pfam PF00581 Rhodanese-like domain 5 94 4.1E-14 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 13 1238 0.0 T 14-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Gene3D G3DSA:3.40.50.300 479 762 1.1E-59 T 14-10-2018 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Gene3D G3DSA:3.40.50.300 763 967 1.2E-48 T 14-10-2018 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 SUPERFAMILY SSF52980 1018 1233 7.51E-39 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 465 2.4E-82 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1058 1230 2.5E-10 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Gene3D G3DSA:3.40.50.300 6 211 1.0E-40 T 14-10-2018 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Gene3D G3DSA:3.40.50.300 351 478 1.5E-31 T 14-10-2018 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Pfam PF13361 UvrD-like helicase C-terminal domain 476 889 7.1E-30 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 SUPERFAMILY SSF52540 7 893 5.45E-119 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 11 1239 20.125 T 14-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 C2I25_05710 4f0a7dcbc3a0aeb29ae2ba6c84914a1b 1241 Gene3D G3DSA:3.90.320.10 998 1239 1.0E-80 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 ProSitePatterns PS00080 Multicopper oxidases signature 2. 511 522 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 ProSitePatterns PS00079 Multicopper oxidases signature 1. 506 526 - T 14-10-2018 IPR033138 Multicopper oxidases, conserved site C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 SUPERFAMILY SSF49503 385 524 4.95E-37 T 14-10-2018 IPR008972 Cupredoxin C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 Gene3D G3DSA:2.60.40.420 397 540 2.1E-40 T 14-10-2018 IPR008972 Cupredoxin C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 Pfam PF07732 Multicopper oxidase 65 175 9.1E-36 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 Pfam PF07731 Multicopper oxidase 417 527 1.3E-29 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 Pfam PF00394 Multicopper oxidase 254 363 8.0E-15 T 14-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 SUPERFAMILY SSF49503 177 375 8.45E-28 T 14-10-2018 IPR008972 Cupredoxin C2I25_02150 8066ec4cd94682f34c34ccacb26e8cdf 546 SUPERFAMILY SSF49503 49 175 3.28E-37 T 14-10-2018 IPR008972 Cupredoxin C2I25_11650 497e9c4a1564a7769e7dd6a69b2e8e50 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 14-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11650 497e9c4a1564a7769e7dd6a69b2e8e50 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.359 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11650 497e9c4a1564a7769e7dd6a69b2e8e50 44 Pfam PF00468 Ribosomal protein L34 1 44 2.8E-24 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11650 497e9c4a1564a7769e7dd6a69b2e8e50 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 3.0E-16 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11650 497e9c4a1564a7769e7dd6a69b2e8e50 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 8.4E-22 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 Pfam PF01476 LysM domain 32 74 1.3E-12 T 14-10-2018 IPR018392 LysM domain C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 Pfam PF01476 LysM domain 99 140 4.6E-12 T 14-10-2018 IPR018392 LysM domain C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 SUPERFAMILY SSF54106 30 74 1.06E-10 T 14-10-2018 C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 Pfam PF07486 Cell Wall Hydrolase 162 263 3.2E-23 T 14-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 SUPERFAMILY SSF54106 97 140 1.83E-11 T 14-10-2018 C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 Gene3D G3DSA:1.10.10.2520 149 229 2.8E-27 T 14-10-2018 C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 Gene3D G3DSA:3.10.350.10 85 148 1.5E-15 T 14-10-2018 IPR036779 LysM domain superfamily C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 Gene3D G3DSA:3.10.350.10 20 84 9.2E-17 T 14-10-2018 IPR036779 LysM domain superfamily C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 Gene3D G3DSA:2.40.10.420 233 265 4.5E-13 T 14-10-2018 C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 SMART SM00257 98 141 2.7E-12 T 14-10-2018 IPR018392 LysM domain C2I25_20705 81e5b4c50ecfcc88dbf5a0e8a1950964 265 SMART SM00257 31 74 4.6E-12 T 14-10-2018 IPR018392 LysM domain C2I25_10970 ec879859a6ca8ca9fa4844a9f1adb622 210 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.709 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10970 ec879859a6ca8ca9fa4844a9f1adb622 210 SUPERFAMILY SSF50447 1 208 4.15E-83 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I25_10970 ec879859a6ca8ca9fa4844a9f1adb622 210 Gene3D G3DSA:2.40.50.620 33 97 4.7E-16 T 14-10-2018 C2I25_10970 ec879859a6ca8ca9fa4844a9f1adb622 210 Gene3D G3DSA:2.40.30.10 133 209 1.2E-17 T 14-10-2018 C2I25_10970 ec879859a6ca8ca9fa4844a9f1adb622 210 Pfam PF00297 Ribosomal protein L3 99 181 1.9E-17 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10970 ec879859a6ca8ca9fa4844a9f1adb622 210 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 7.4E-89 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10970 ec879859a6ca8ca9fa4844a9f1adb622 210 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site C2I25_05530 31f3f0ac382d0836df9c6b11ec61411e 310 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 308 4.8E-134 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I25_05530 31f3f0ac382d0836df9c6b11ec61411e 310 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 9.5E-32 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I25_05530 31f3f0ac382d0836df9c6b11ec61411e 310 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 308 1.8E-36 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I25_05530 31f3f0ac382d0836df9c6b11ec61411e 310 Gene3D G3DSA:3.40.47.10 1 310 1.7E-134 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_05530 31f3f0ac382d0836df9c6b11ec61411e 310 SUPERFAMILY SSF53901 3 308 1.56E-72 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_05530 31f3f0ac382d0836df9c6b11ec61411e 310 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 308 73.001 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I25_19285 4bdf1c7bf2069bad43430769f6a69c4f 219 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 4 217 3.7E-120 T 14-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 C2I25_19285 4bdf1c7bf2069bad43430769f6a69c4f 219 SUPERFAMILY SSF56784 3 217 4.65E-56 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_19285 4bdf1c7bf2069bad43430769f6a69c4f 219 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 4 185 2.6E-52 T 14-10-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 C2I25_19285 4bdf1c7bf2069bad43430769f6a69c4f 219 Gene3D G3DSA:3.90.1470.20 14 133 4.1E-71 T 14-10-2018 C2I25_19285 4bdf1c7bf2069bad43430769f6a69c4f 219 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 1 215 50.938 T 14-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 C2I25_19285 4bdf1c7bf2069bad43430769f6a69c4f 219 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 177 7.9E-32 T 14-10-2018 C2I25_19285 4bdf1c7bf2069bad43430769f6a69c4f 219 Gene3D G3DSA:3.40.50.1000 5 209 4.1E-71 T 14-10-2018 IPR023214 HAD superfamily C2I25_19285 4bdf1c7bf2069bad43430769f6a69c4f 219 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 176 2.7E-19 T 14-10-2018 C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 SUPERFAMILY SSF50129 1 181 1.24E-58 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 Gene3D G3DSA:3.90.180.10 9 334 5.8E-114 T 14-10-2018 C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 SMART SM00829 8 347 6.3E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 Pfam PF00107 Zinc-binding dehydrogenase 182 309 4.0E-29 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 21 4.7E-6 T 14-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 SUPERFAMILY SSF51735 146 313 6.97E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 141 2.2E-35 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_08125 40f97b314f3bf09850d1691c8f936998 350 Gene3D G3DSA:3.40.50.720 159 295 5.8E-114 T 14-10-2018 C2I25_23515 56f8e151451ee8d1563a8882a66a2590 225 Pfam PF00072 Response regulator receiver domain 6 111 9.7E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_23515 56f8e151451ee8d1563a8882a66a2590 225 SMART SM00448 4 114 4.5E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_23515 56f8e151451ee8d1563a8882a66a2590 225 SUPERFAMILY SSF52172 1 169 4.68E-39 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_23515 56f8e151451ee8d1563a8882a66a2590 225 SMART SM00862 147 222 8.7E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_23515 56f8e151451ee8d1563a8882a66a2590 225 Gene3D G3DSA:1.10.10.10 128 225 1.4E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23515 56f8e151451ee8d1563a8882a66a2590 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 5.2E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_23515 56f8e151451ee8d1563a8882a66a2590 225 Gene3D G3DSA:3.40.50.2300 1 127 2.6E-34 T 14-10-2018 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 Pfam PF13637 Ankyrin repeats (many copies) 191 233 7.6E-8 T 14-10-2018 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 Gene3D G3DSA:1.25.40.20 43 239 5.9E-54 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 PRINTS PR01415 Ankyrin repeat signature 142 157 1.8E-7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 PRINTS PR01415 Ankyrin repeat signature 196 210 1.8E-7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 SMART SM00248 141 171 0.042 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 SMART SM00248 75 104 0.0018 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 SMART SM00248 108 137 0.096 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 SMART SM00248 43 71 1700.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 SMART SM00248 213 243 170.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 SMART SM00248 175 209 0.18 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 SUPERFAMILY SSF48403 46 239 6.3E-50 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I25_08670 407e1c71c950985da7bf53ff61bbb8da 249 Pfam PF12796 Ankyrin repeats (3 copies) 106 173 4.1E-12 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain C2I25_04995 d5fdfe2d60b43c22a471501f832d27c6 455 Pfam PF00171 Aldehyde dehydrogenase family 7 427 1.0E-88 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_04995 d5fdfe2d60b43c22a471501f832d27c6 455 Gene3D G3DSA:3.40.605.10 12 427 1.2E-172 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_04995 d5fdfe2d60b43c22a471501f832d27c6 455 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 208 215 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I25_04995 d5fdfe2d60b43c22a471501f832d27c6 455 SUPERFAMILY SSF53720 5 434 2.23E-121 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_04995 d5fdfe2d60b43c22a471501f832d27c6 455 PIRSF PIRSF036492 1 455 4.1E-183 T 14-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 C2I25_04995 d5fdfe2d60b43c22a471501f832d27c6 455 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 236 247 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I25_04995 d5fdfe2d60b43c22a471501f832d27c6 455 Gene3D G3DSA:3.40.309.10 212 407 1.2E-172 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_13480 2fceab70dcaa2dc7046903637f81415f 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 3.0E-18 T 14-10-2018 IPR012452 Protein of unknown function DUF1657 C2I25_04100 2199db3ca00f623493a9d4f1a49f1758 176 Gene3D G3DSA:1.10.443.10 5 176 3.1E-27 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_04100 2199db3ca00f623493a9d4f1a49f1758 176 Pfam PF00589 Phage integrase family 11 173 1.7E-22 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_04100 2199db3ca00f623493a9d4f1a49f1758 176 SUPERFAMILY SSF56349 8 175 7.95E-34 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 Pfam PF00814 Glycoprotease family 27 311 4.0E-109 T 14-10-2018 IPR000905 Gcp-like domain C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 311 1.7E-112 T 14-10-2018 IPR017861 Kae1/TsaD family C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 2.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 2.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 2.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 2.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 2.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 2.4E-50 T 14-10-2018 IPR017861 Kae1/TsaD family C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 Gene3D G3DSA:3.30.420.40 132 298 5.4E-127 T 14-10-2018 C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 SUPERFAMILY SSF53067 105 313 9.72E-47 T 14-10-2018 C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 SUPERFAMILY SSF53067 6 126 3.3E-33 T 14-10-2018 C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 336 66.538 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 Gene3D G3DSA:3.30.420.40 7 320 5.4E-127 T 14-10-2018 C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 14-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 C2I25_10135 c17ee4bafaec24849ce25ab81b0af1b1 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 318 4.5E-137 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 C2I25_10410 ce92c75ea84a492a23668505cfed657b 253 SUPERFAMILY SSF54197 13 130 2.08E-23 T 14-10-2018 IPR036265 HIT-like superfamily C2I25_10410 ce92c75ea84a492a23668505cfed657b 253 PIRSF PIRSF031505 1 253 2.9E-130 T 14-10-2018 IPR012361 Galactose-1-phosphate uridylyltransferase, short form, putative C2I25_10410 ce92c75ea84a492a23668505cfed657b 253 Gene3D G3DSA:3.30.428.10 56 131 4.4E-12 T 14-10-2018 IPR036265 HIT-like superfamily C2I25_10410 ce92c75ea84a492a23668505cfed657b 253 Pfam PF16285 Domain of unknown function (DUF4931) 8 251 3.1E-123 T 14-10-2018 C2I25_03135 f8d72178a7521aacadf3e8ac1c797189 524 Pfam PF01514 Secretory protein of YscJ/FliF family 20 211 1.7E-42 T 14-10-2018 IPR006182 Secretory protein YscJ/FliF C2I25_03135 f8d72178a7521aacadf3e8ac1c797189 524 Gene3D G3DSA:3.30.300.30 108 216 7.3E-7 T 14-10-2018 C2I25_03135 f8d72178a7521aacadf3e8ac1c797189 524 Pfam PF08345 Flagellar M-ring protein C-terminal 247 407 2.9E-19 T 14-10-2018 IPR013556 Flagellar M-ring C-terminal C2I25_03135 f8d72178a7521aacadf3e8ac1c797189 524 PRINTS PR01009 Flagellar M-ring protein signature 187 205 1.4E-7 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I25_03135 f8d72178a7521aacadf3e8ac1c797189 524 PRINTS PR01009 Flagellar M-ring protein signature 337 361 1.4E-7 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I25_03135 f8d72178a7521aacadf3e8ac1c797189 524 PRINTS PR01009 Flagellar M-ring protein signature 143 157 1.4E-7 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I25_03740 f389e79249984082cc93aa592b96c5a1 113 PIRSF PIRSF029904 1 111 1.1E-56 T 14-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD C2I25_03740 f389e79249984082cc93aa592b96c5a1 113 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 104 4.8E-20 T 14-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core C2I25_03740 f389e79249984082cc93aa592b96c5a1 113 SUPERFAMILY SSF101386 4 104 1.96E-28 T 14-10-2018 C2I25_03740 f389e79249984082cc93aa592b96c5a1 113 Gene3D G3DSA:1.10.287.1080 2 113 3.1E-35 T 14-10-2018 C2I25_24930 66996d7d8c66de8283d9df7901daada7 229 Gene3D G3DSA:3.40.50.10300 2 223 3.2E-50 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I25_24930 66996d7d8c66de8283d9df7901daada7 229 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 1 182 1.6E-30 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I25_24930 66996d7d8c66de8283d9df7901daada7 229 SUPERFAMILY SSF102645 2 222 2.22E-43 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I25_25965 1f2f87141f53b7a4202f551cd7b1fbf7 178 Gene3D G3DSA:1.20.120.450 19 169 9.0E-33 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_25965 1f2f87141f53b7a4202f551cd7b1fbf7 178 Pfam PF12867 DinB superfamily 30 164 1.2E-20 T 14-10-2018 IPR024775 DinB-like domain C2I25_25965 1f2f87141f53b7a4202f551cd7b1fbf7 178 SUPERFAMILY SSF109854 5 167 5.19E-36 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_26620 00d0c1567f2af81973294f5a48f8595f 109 Gene3D G3DSA:3.90.10.10 7 103 5.8E-5 T 14-10-2018 C2I25_26620 00d0c1567f2af81973294f5a48f8595f 109 Pfam PF01844 HNH endonuclease 44 90 8.5E-11 T 14-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 C2I25_26620 00d0c1567f2af81973294f5a48f8595f 109 SMART SM00507 31 87 2.1E-9 T 14-10-2018 IPR003615 HNH nuclease C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 Gene3D G3DSA:1.10.10.10 1 65 2.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 Gene3D G3DSA:3.30.930.10 69 278 3.3E-70 T 14-10-2018 C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 Pfam PF03099 Biotin/lipoate A/B protein ligase family 92 214 8.7E-20 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 SUPERFAMILY SSF50037 282 325 1.37E-5 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 88 324 3.0E-70 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 SUPERFAMILY SSF46785 3 61 2.09E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 Pfam PF08279 HTH domain 6 60 1.1E-15 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 Pfam PF02237 Biotin protein ligase C terminal domain 280 324 3.6E-9 T 14-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 326 38.791 T 14-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 SUPERFAMILY SSF55681 72 276 1.99E-62 T 14-10-2018 C2I25_03710 e07991a07c7b2f0c2ae586973e23893d 326 Gene3D G3DSA:2.30.30.100 280 326 1.1E-8 T 14-10-2018 C2I25_04855 da856972a6fd5e9856d63a90a1ce4259 174 Pfam PF09602 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) 1 164 1.5E-66 T 14-10-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP C2I25_04855 da856972a6fd5e9856d63a90a1ce4259 174 TIGRFAM TIGR02131 phaP_Bmeg: polyhydroxyalkanoic acid inclusion protein PhaP 1 164 1.1E-84 T 14-10-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP C2I25_27035 1050467c02615b4eea3aa3ebaad64716 245 SUPERFAMILY SSF53167 10 236 4.45E-49 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I25_27035 1050467c02615b4eea3aa3ebaad64716 245 Pfam PF01048 Phosphorylase superfamily 12 234 1.2E-38 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I25_27035 1050467c02615b4eea3aa3ebaad64716 245 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 12 219 2.8E-21 T 14-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_27035 1050467c02615b4eea3aa3ebaad64716 245 Gene3D G3DSA:3.40.50.1580 3 242 4.7E-45 T 14-10-2018 C2I25_04580 f63bdae66462e343d939669638a3e860 365 SUPERFAMILY SSF51412 5 363 1.25E-66 T 14-10-2018 C2I25_04580 f63bdae66462e343d939669638a3e860 365 Gene3D G3DSA:3.20.20.70 4 359 1.1E-116 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_04580 f63bdae66462e343d939669638a3e860 365 Pfam PF03060 Nitronate monooxygenase 5 346 3.5E-92 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 C2I25_15680 1fc47569a349249130162a17766db6e9 78 ProDom PD058325 YUSG BH3483 1 78 2.0E-39 T 14-10-2018 IPR020140 Uncharacterised protein family YusG C2I25_15680 1fc47569a349249130162a17766db6e9 78 Pfam PF10830 Protein of unknown function (DUF2553) 6 78 9.8E-16 T 14-10-2018 IPR020140 Uncharacterised protein family YusG C2I25_17935 2faaf1bf5a40fe0876b1606ef77d3414 288 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 21 287 5.8E-79 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 C2I25_17935 2faaf1bf5a40fe0876b1606ef77d3414 288 SUPERFAMILY SSF161098 19 284 9.35E-37 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_17935 2faaf1bf5a40fe0876b1606ef77d3414 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 284 2.7E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_17935 2faaf1bf5a40fe0876b1606ef77d3414 288 Gene3D G3DSA:1.10.3720.10 61 288 3.4E-32 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_21980 a7a81c72f6eb524bb7e9a4e8a78d010e 422 Gene3D G3DSA:3.20.20.80 50 390 1.4E-51 T 14-10-2018 C2I25_21980 a7a81c72f6eb524bb7e9a4e8a78d010e 422 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 191 200 - T 14-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 C2I25_21980 a7a81c72f6eb524bb7e9a4e8a78d010e 422 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 64 377 3.4E-24 T 14-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 C2I25_21980 a7a81c72f6eb524bb7e9a4e8a78d010e 422 SUPERFAMILY SSF51445 47 403 3.53E-51 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_07080 f7fd976d524bcfa549d5f89bdd39b3d7 586 Pfam PF00664 ABC transporter transmembrane region 21 292 7.3E-42 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_07080 f7fd976d524bcfa549d5f89bdd39b3d7 586 Gene3D G3DSA:1.20.1560.10 3 320 6.9E-78 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_07080 f7fd976d524bcfa549d5f89bdd39b3d7 586 SMART SM00382 363 555 1.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_07080 f7fd976d524bcfa549d5f89bdd39b3d7 586 Gene3D G3DSA:3.40.50.300 328 584 5.1E-82 T 14-10-2018 C2I25_07080 f7fd976d524bcfa549d5f89bdd39b3d7 586 SUPERFAMILY SSF52540 327 573 5.98E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07080 f7fd976d524bcfa549d5f89bdd39b3d7 586 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_07080 f7fd976d524bcfa549d5f89bdd39b3d7 586 SUPERFAMILY SSF90123 8 325 1.31E-73 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_07080 f7fd976d524bcfa549d5f89bdd39b3d7 586 Pfam PF00005 ABC transporter 354 501 1.9E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_02480 357f27e6d7a568b1b353648186870a2b 445 SUPERFAMILY SSF161070 5 442 1.57E-132 T 14-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 C2I25_02480 357f27e6d7a568b1b353648186870a2b 445 Pfam PF00209 Sodium:neurotransmitter symporter family 148 440 1.4E-29 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_02480 357f27e6d7a568b1b353648186870a2b 445 Pfam PF00209 Sodium:neurotransmitter symporter family 4 122 3.2E-23 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_02480 357f27e6d7a568b1b353648186870a2b 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 40 59 8.4E-12 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_02480 357f27e6d7a568b1b353648186870a2b 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 86 112 8.4E-12 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_02480 357f27e6d7a568b1b353648186870a2b 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 11 32 8.4E-12 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_15765 cf45065d82b7929e9f0ca0566ad72016 284 SMART SM00849 50 257 1.3E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_15765 cf45065d82b7929e9f0ca0566ad72016 284 Gene3D G3DSA:3.60.15.10 4 269 2.1E-87 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_15765 cf45065d82b7929e9f0ca0566ad72016 284 SUPERFAMILY SSF56281 3 263 1.02E-46 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_15765 cf45065d82b7929e9f0ca0566ad72016 284 Pfam PF00753 Metallo-beta-lactamase superfamily 55 232 1.3E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_01755 57ffdcf68ffa9a567000c34d7918708d 335 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 99 247 1.8E-37 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_01755 57ffdcf68ffa9a567000c34d7918708d 335 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 99 246 1.2E-42 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_01755 57ffdcf68ffa9a567000c34d7918708d 335 Gene3D G3DSA:1.10.260.150 57 335 4.1E-86 T 14-10-2018 C2I25_01115 e04e306192be16fcbf6e91bb4e28f696 127 SUPERFAMILY SSF54593 1 125 1.01E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_01115 e04e306192be16fcbf6e91bb4e28f696 127 Gene3D G3DSA:3.10.180.10 1 125 6.3E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_01115 e04e306192be16fcbf6e91bb4e28f696 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 120 1.3E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_23130 462254b368044c2b3cf50cfb2b0f3ddf 304 Gene3D G3DSA:3.90.1200.10 119 299 3.7E-12 T 14-10-2018 C2I25_23130 462254b368044c2b3cf50cfb2b0f3ddf 304 Pfam PF01636 Phosphotransferase enzyme family 190 247 3.3E-7 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_23130 462254b368044c2b3cf50cfb2b0f3ddf 304 SUPERFAMILY SSF56112 22 250 4.37E-23 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 92 111 1.1E-44 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 72 92 1.1E-44 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 180 200 1.1E-44 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 225 250 1.1E-44 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 201 222 1.1E-44 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 53 72 1.1E-44 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 Pfam PF00813 FliP family 55 245 8.7E-57 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 173 185 1.9E-6 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 123 137 1.9E-6 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 111 123 1.9E-6 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I25_03030 79186af04c2288da72ce2068b81f699f 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 51 60 1.9E-6 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Gene3D G3DSA:3.10.20.30 3 66 1.4E-23 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 SMART SM00863 173 222 2.1E-23 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 173 222 2.3E-15 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Gene3D G3DSA:3.30.980.10 73 225 5.4E-64 T 14-10-2018 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 SUPERFAMILY SSF52954 529 638 5.59E-31 T 14-10-2018 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Gene3D G3DSA:3.30.930.10 226 533 2.5E-134 T 14-10-2018 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 SUPERFAMILY SSF55681 246 528 1.58E-97 T 14-10-2018 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 70 637 35.155 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 332 360 4.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 365 388 4.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 466 494 4.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 509 522 4.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 548 4.7E-53 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 76 634 6.5E-234 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Pfam PF02824 TGS domain 7 65 5.9E-12 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 326 530 8.0E-42 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 SUPERFAMILY SSF81271 6 65 5.23E-15 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 SUPERFAMILY SSF55186 67 244 1.14E-65 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Pfam PF03129 Anticodon binding domain 543 633 6.8E-20 T 14-10-2018 IPR004154 Anticodon-binding C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Gene3D G3DSA:3.40.50.800 534 640 4.7E-32 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily C2I25_28080 ab1de09f6b8b617f4e8c42c451aac3a3 640 Gene3D G3DSA:3.30.54.20 134 190 5.4E-64 T 14-10-2018 C2I25_25635 150a8513949e4f8af961b0bda6e415da 285 SUPERFAMILY SSF53850 26 284 4.98E-82 T 14-10-2018 C2I25_25635 150a8513949e4f8af961b0bda6e415da 285 Gene3D G3DSA:3.40.190.100 112 219 4.2E-94 T 14-10-2018 C2I25_25635 150a8513949e4f8af961b0bda6e415da 285 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 31 274 3.1E-69 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 C2I25_25635 150a8513949e4f8af961b0bda6e415da 285 Gene3D G3DSA:3.40.190.10 32 283 4.2E-94 T 14-10-2018 C2I25_07765 9858085493dabb0886587d0815c9aa3d 139 Gene3D G3DSA:3.10.580.10 1 138 1.7E-35 T 14-10-2018 C2I25_07765 9858085493dabb0886587d0815c9aa3d 139 SUPERFAMILY SSF54631 1 117 6.06E-33 T 14-10-2018 C2I25_07765 9858085493dabb0886587d0815c9aa3d 139 Pfam PF00571 CBS domain 4 54 6.7E-11 T 14-10-2018 IPR000644 CBS domain C2I25_07765 9858085493dabb0886587d0815c9aa3d 139 Pfam PF00571 CBS domain 69 118 7.8E-13 T 14-10-2018 IPR000644 CBS domain C2I25_07765 9858085493dabb0886587d0815c9aa3d 139 SMART SM00116 75 122 7.2E-12 T 14-10-2018 IPR000644 CBS domain C2I25_07765 9858085493dabb0886587d0815c9aa3d 139 SMART SM00116 11 58 0.0014 T 14-10-2018 IPR000644 CBS domain C2I25_06255 4dc9582df463c4e95d6ff6186a89f2bd 258 Pfam PF04892 VanZ like family 93 239 4.3E-7 T 14-10-2018 IPR006976 VanZ-like C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 ProSitePatterns PS00331 Malic enzymes signature. 157 173 - T 14-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 SMART SM00919 161 385 5.7E-136 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 SMART SM01274 16 149 2.6E-86 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 SUPERFAMILY SSF51735 161 405 1.46E-84 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 Pfam PF03949 Malic enzyme, NAD binding domain 163 384 3.0E-25 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 SUPERFAMILY SSF53223 7 159 1.58E-57 T 14-10-2018 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 PRINTS PR00072 Malic enzyme signature 157 173 1.5E-8 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 PRINTS PR00072 Malic enzyme signature 78 100 1.5E-8 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 PRINTS PR00072 Malic enzyme signature 188 204 1.5E-8 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 PIRSF PIRSF000106 37 408 2.2E-86 T 14-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 Gene3D G3DSA:3.40.50.720 159 411 2.0E-89 T 14-10-2018 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 Pfam PF00390 Malic enzyme, N-terminal domain 16 149 7.9E-31 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I25_16280 772ef0ba1d08e392d2b795b2d63c43ad 412 Gene3D G3DSA:3.40.50.10380 2 158 7.4E-75 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 C2I25_02325 0b53467067aa3206ae736a981192fafa 232 SMART SM00862 154 230 1.1E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_02325 0b53467067aa3206ae736a981192fafa 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 1.5E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_02325 0b53467067aa3206ae736a981192fafa 232 SUPERFAMILY SSF52172 3 131 1.17E-41 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_02325 0b53467067aa3206ae736a981192fafa 232 SMART SM00448 4 114 4.8E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_02325 0b53467067aa3206ae736a981192fafa 232 Gene3D G3DSA:3.40.50.2300 2 131 1.4E-38 T 14-10-2018 C2I25_02325 0b53467067aa3206ae736a981192fafa 232 Gene3D G3DSA:1.10.10.10 132 232 1.8E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02325 0b53467067aa3206ae736a981192fafa 232 Pfam PF00072 Response regulator receiver domain 6 114 2.4E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_02325 0b53467067aa3206ae736a981192fafa 232 SUPERFAMILY SSF46894 133 230 3.12E-27 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_17440 3f39468d5e00d844a6334dcf168c9f24 345 Pfam PF01032 FecCD transport family 31 337 4.2E-97 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_17440 3f39468d5e00d844a6334dcf168c9f24 345 SUPERFAMILY SSF81345 15 337 5.1E-84 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_17440 3f39468d5e00d844a6334dcf168c9f24 345 Gene3D G3DSA:1.10.3470.10 18 342 1.2E-97 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_27025 654a1bd5045e8a1146be7c6f65276728 282 Pfam PF13673 Acetyltransferase (GNAT) domain 172 247 2.1E-8 T 14-10-2018 IPR000182 GNAT domain C2I25_27025 654a1bd5045e8a1146be7c6f65276728 282 SUPERFAMILY SSF55729 1 208 6.22E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27025 654a1bd5045e8a1146be7c6f65276728 282 Gene3D G3DSA:3.40.630.30 1 141 2.6E-20 T 14-10-2018 C2I25_27025 654a1bd5045e8a1146be7c6f65276728 282 Gene3D G3DSA:3.40.630.30 142 275 1.6E-10 T 14-10-2018 C2I25_27025 654a1bd5045e8a1146be7c6f65276728 282 Pfam PF00583 Acetyltransferase (GNAT) family 51 134 3.6E-13 T 14-10-2018 IPR000182 GNAT domain C2I25_27025 654a1bd5045e8a1146be7c6f65276728 282 SUPERFAMILY SSF55729 182 272 1.72E-8 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_17540 843ab7f045a9e67010ed4a32071c16d7 277 Gene3D G3DSA:3.40.630.30 2 128 6.5E-16 T 14-10-2018 C2I25_17540 843ab7f045a9e67010ed4a32071c16d7 277 Pfam PF13673 Acetyltransferase (GNAT) domain 42 122 4.1E-11 T 14-10-2018 IPR000182 GNAT domain C2I25_17540 843ab7f045a9e67010ed4a32071c16d7 277 SUPERFAMILY SSF55729 1 256 2.23E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_13995 4ed9682c59d4b05135f08774949262b4 436 PIRSF PIRSF006060 1 436 2.0E-81 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_13995 4ed9682c59d4b05135f08774949262b4 436 Gene3D G3DSA:1.20.1740.10 3 436 1.1E-93 T 14-10-2018 C2I25_13995 4ed9682c59d4b05135f08774949262b4 436 Pfam PF13520 Amino acid permease 11 406 2.5E-61 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_22790 840b89bd26b1d0454bfe058590b54276 113 Gene3D G3DSA:2.20.25.10 1 42 1.2E-20 T 14-10-2018 C2I25_22790 840b89bd26b1d0454bfe058590b54276 113 Pfam PF08274 PhnA Zinc-Ribbon 4 32 4.2E-17 T 14-10-2018 IPR013987 PhnA protein, N-terminal C2I25_22790 840b89bd26b1d0454bfe058590b54276 113 SUPERFAMILY SSF82057 41 113 2.11E-29 T 14-10-2018 C2I25_22790 840b89bd26b1d0454bfe058590b54276 113 SUPERFAMILY SSF57783 3 36 6.12E-15 T 14-10-2018 C2I25_22790 840b89bd26b1d0454bfe058590b54276 113 Gene3D G3DSA:2.30.30.40 43 113 3.3E-35 T 14-10-2018 C2I25_22790 840b89bd26b1d0454bfe058590b54276 113 Pfam PF03831 PhnA domain 46 113 9.0E-34 T 14-10-2018 IPR013988 PhnA protein, C-terminal C2I25_22790 840b89bd26b1d0454bfe058590b54276 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 112 1.8E-50 T 14-10-2018 IPR004624 PhnA protein C2I25_08615 112e8065d573ef5f42013dbea9352e4f 251 Gene3D G3DSA:3.90.70.10 52 251 5.5E-88 T 14-10-2018 C2I25_08615 112e8065d573ef5f42013dbea9352e4f 251 Pfam PF13529 Peptidase_C39 like family 59 218 9.3E-44 T 14-10-2018 IPR039564 Peptidase C39-like C2I25_08615 112e8065d573ef5f42013dbea9352e4f 251 PIRSF PIRSF032442 2 248 6.3E-85 T 14-10-2018 IPR016997 Uncharacterised conserved protein UCP032442 C2I25_07620 a6a18b09c1e9d3e35fc5a5dd2051a3ff 410 Pfam PF02687 FtsX-like permease family 305 401 1.3E-5 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_07620 a6a18b09c1e9d3e35fc5a5dd2051a3ff 410 Pfam PF12704 MacB-like periplasmic core domain 18 245 2.6E-6 T 14-10-2018 IPR025857 MacB-like periplasmic core domain C2I25_02950 41a8c375ce7c3fca66c4d7d67f22221a 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 3.4E-21 T 14-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I25_02950 41a8c375ce7c3fca66c4d7d67f22221a 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 3.3E-27 T 14-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I25_02950 41a8c375ce7c3fca66c4d7d67f22221a 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 4.0E-27 T 14-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I25_02950 41a8c375ce7c3fca66c4d7d67f22221a 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 18.461 T 14-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I25_02695 183858e341ff521e11a1456cb03a225c 181 Gene3D G3DSA:2.60.120.10 71 176 5.1E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_02695 183858e341ff521e11a1456cb03a225c 181 Gene3D G3DSA:1.10.260.40 1 70 3.7E-19 T 14-10-2018 C2I25_02695 183858e341ff521e11a1456cb03a225c 181 Pfam PF07883 Cupin domain 106 174 3.9E-15 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_02695 183858e341ff521e11a1456cb03a225c 181 Pfam PF01381 Helix-turn-helix 10 61 1.7E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_02695 183858e341ff521e11a1456cb03a225c 181 SMART SM00530 9 64 3.6E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_02695 183858e341ff521e11a1456cb03a225c 181 SUPERFAMILY SSF47413 3 72 3.1E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_02695 183858e341ff521e11a1456cb03a225c 181 SUPERFAMILY SSF51182 57 181 1.96E-25 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_04700 cd3390fd5641a98581df82f255283541 238 Pfam PF04055 Radical SAM superfamily 28 122 6.2E-12 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_04700 cd3390fd5641a98581df82f255283541 238 PIRSF PIRSF000370 2 238 1.1E-50 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 C2I25_04700 cd3390fd5641a98581df82f255283541 238 Gene3D G3DSA:3.20.20.70 4 214 1.2E-30 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_04700 cd3390fd5641a98581df82f255283541 238 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 235 35.745 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 C2I25_04700 cd3390fd5641a98581df82f255283541 238 Pfam PF13353 4Fe-4S single cluster domain 14 117 7.0E-10 T 14-10-2018 C2I25_04700 cd3390fd5641a98581df82f255283541 238 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 3 238 3.0E-119 T 14-10-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 C2I25_04700 cd3390fd5641a98581df82f255283541 238 SUPERFAMILY SSF102114 26 175 7.72E-14 T 14-10-2018 C2I25_17465 eb25d2615fd49a686252ee12f6f2b6d2 152 SUPERFAMILY SSF55729 19 130 4.88E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_17465 eb25d2615fd49a686252ee12f6f2b6d2 152 Pfam PF13508 Acetyltransferase (GNAT) domain 57 128 6.3E-10 T 14-10-2018 IPR000182 GNAT domain C2I25_17465 eb25d2615fd49a686252ee12f6f2b6d2 152 Gene3D G3DSA:3.40.630.30 11 139 3.1E-23 T 14-10-2018 C2I25_03620 65d898aafd111d09b4a8163319297a65 114 Gene3D G3DSA:1.20.120.440 1 114 3.9E-33 T 14-10-2018 IPR023351 YppE-like superfamily C2I25_03620 65d898aafd111d09b4a8163319297a65 114 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 11 112 4.2E-35 T 14-10-2018 IPR014913 Protein of unknown function DUF1798 C2I25_03620 65d898aafd111d09b4a8163319297a65 114 SUPERFAMILY SSF140415 1 114 3.14E-40 T 14-10-2018 IPR023351 YppE-like superfamily C2I25_26135 120458c03358db6eb26fbc7b2ee8db1c 307 SUPERFAMILY SSF51126 9 243 2.24E-11 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor C2I25_26135 120458c03358db6eb26fbc7b2ee8db1c 307 Gene3D G3DSA:2.160.20.10 19 284 4.8E-11 T 14-10-2018 IPR012334 Pectin lyase fold C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 1.4E-37 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 293 1.4E-37 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 256 1.4E-37 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 274 1.4E-37 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 1.4E-37 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 SUPERFAMILY SSF52317 140 354 8.25E-59 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 SMART SM01097 1 131 5.0E-89 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 240 251 8.0E-12 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 8.0E-12 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 326 339 8.0E-12 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 352 2.3E-148 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 Gene3D G3DSA:3.50.30.20 1 148 3.1E-56 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 355 49.045 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 Pfam PF00117 Glutamine amidotransferase class-I 173 349 3.6E-48 T 14-10-2018 IPR017926 Glutamine amidotransferase C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 SUPERFAMILY SSF52021 1 145 1.02E-57 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 3.0E-52 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00097 Anthranilate synthase component II signature 213 222 6.0E-7 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00097 Anthranilate synthase component II signature 326 339 6.0E-7 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00097 Anthranilate synthase component II signature 240 251 6.0E-7 T 14-10-2018 C2I25_20060 034b277043a541f3b7de25676ec3fdc1 365 Gene3D G3DSA:3.40.50.880 164 360 9.1E-36 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_09425 bc537e167cfab67c73d3e405ba94fd06 222 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 18 213 7.2E-67 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09425 bc537e167cfab67c73d3e405ba94fd06 222 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 16 219 28.512 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09425 bc537e167cfab67c73d3e405ba94fd06 222 SUPERFAMILY SSF51391 8 217 7.46E-68 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_09425 bc537e167cfab67c73d3e405ba94fd06 222 Gene3D G3DSA:3.20.20.70 2 221 2.1E-75 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_09425 bc537e167cfab67c73d3e405ba94fd06 222 Pfam PF02581 Thiamine monophosphate synthase 18 201 3.5E-62 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_20355 89eef454d9326d4a150cb992a6b70664 299 Pfam PF00589 Phage integrase family 111 285 2.4E-51 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_20355 89eef454d9326d4a150cb992a6b70664 299 SUPERFAMILY SSF56349 3 293 2.94E-59 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_20355 89eef454d9326d4a150cb992a6b70664 299 Gene3D G3DSA:1.10.150.130 3 98 1.7E-26 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I25_20355 89eef454d9326d4a150cb992a6b70664 299 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 9 299 4.8E-110 T 14-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 C2I25_20355 89eef454d9326d4a150cb992a6b70664 299 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 90 1.1E-23 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I25_20355 89eef454d9326d4a150cb992a6b70664 299 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 299 57.169 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD C2I25_20355 89eef454d9326d4a150cb992a6b70664 299 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 9 299 2.9E-101 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 C2I25_20355 89eef454d9326d4a150cb992a6b70664 299 Gene3D G3DSA:1.10.443.10 111 293 2.6E-62 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_09440 b4cb94e120c92f6eb4b153b6d14a42b2 991 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 173 4.7E-49 T 14-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal C2I25_09440 b4cb94e120c92f6eb4b153b6d14a42b2 991 Pfam PF01061 ABC-2 type transporter 823 939 7.8E-9 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 C2I25_09440 b4cb94e120c92f6eb4b153b6d14a42b2 991 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 770 971 1.8E-49 T 14-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal C2I25_09440 b4cb94e120c92f6eb4b153b6d14a42b2 991 Pfam PF12698 ABC-2 family transporter protein 24 160 1.8E-8 T 14-10-2018 C2I25_06365 5d13a201387be4bc4544df24f7b6b725 46 ProDom PD049467 YFLJ 1 43 2.0E-17 T 14-10-2018 IPR022580 Protein of unknown function DUF2639 C2I25_06365 5d13a201387be4bc4544df24f7b6b725 46 Pfam PF11121 Protein of unknown function (DUF2639) 2 39 1.1E-20 T 14-10-2018 IPR022580 Protein of unknown function DUF2639 C2I25_25530 ecfacee67456db0e4b3ec6fc57de87b0 691 Gene3D G3DSA:3.40.50.300 171 318 3.0E-11 T 14-10-2018 C2I25_25530 ecfacee67456db0e4b3ec6fc57de87b0 691 Pfam PF13361 UvrD-like helicase C-terminal domain 524 619 6.5E-7 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 C2I25_25530 ecfacee67456db0e4b3ec6fc57de87b0 691 Pfam PF13538 UvrD-like helicase C-terminal domain 630 677 1.8E-10 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain C2I25_25530 ecfacee67456db0e4b3ec6fc57de87b0 691 SUPERFAMILY SSF52540 175 683 7.54E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25530 ecfacee67456db0e4b3ec6fc57de87b0 691 Gene3D G3DSA:3.40.50.300 526 691 9.1E-54 T 14-10-2018 C2I25_25530 ecfacee67456db0e4b3ec6fc57de87b0 691 Pfam PF13245 AAA domain 186 503 4.8E-10 T 14-10-2018 C2I25_25530 ecfacee67456db0e4b3ec6fc57de87b0 691 Gene3D G3DSA:3.40.50.300 374 524 1.0E-9 T 14-10-2018 C2I25_07740 00c40d4a6e60d3563febb984a6519040 231 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 217 1.2E-73 T 14-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 C2I25_07740 00c40d4a6e60d3563febb984a6519040 231 PIRSF PIRSF003170 1 218 2.4E-32 T 14-10-2018 IPR026285 TenA_E protein C2I25_07740 00c40d4a6e60d3563febb984a6519040 231 Gene3D G3DSA:1.20.910.10 1 227 7.2E-73 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 C2I25_07740 00c40d4a6e60d3563febb984a6519040 231 SUPERFAMILY SSF48613 1 215 1.78E-75 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 C2I25_07740 00c40d4a6e60d3563febb984a6519040 231 Pfam PF03070 TENA/THI-4/PQQC family 10 216 9.9E-61 T 14-10-2018 IPR004305 Thiaminase-2/PQQC C2I25_19995 14b1c45939b7990f36ae3cd52d0a15a8 224 PIRSF PIRSF004848 1 224 9.3E-63 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 C2I25_19995 14b1c45939b7990f36ae3cd52d0a15a8 224 SUPERFAMILY SSF51419 2 222 2.76E-67 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_19995 14b1c45939b7990f36ae3cd52d0a15a8 224 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 3 222 7.9E-49 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 C2I25_19995 14b1c45939b7990f36ae3cd52d0a15a8 224 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 C2I25_19995 14b1c45939b7990f36ae3cd52d0a15a8 224 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 223 26.878 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 C2I25_19995 14b1c45939b7990f36ae3cd52d0a15a8 224 Pfam PF01168 Alanine racemase, N-terminal domain 13 222 2.8E-17 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_19995 14b1c45939b7990f36ae3cd52d0a15a8 224 Gene3D G3DSA:3.20.20.10 1 224 8.3E-69 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 16 553 2.1E-264 T 14-10-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 SUPERFAMILY SSF52518 12 182 4.32E-53 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 181 2.8E-55 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 333 4.9E-27 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 Gene3D G3DSA:3.40.50.1220 192 366 3.6E-37 T 14-10-2018 C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 542 2.7E-43 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 433 452 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 SUPERFAMILY SSF52518 375 552 2.56E-59 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 SUPERFAMILY SSF52467 194 360 6.54E-35 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 Gene3D G3DSA:3.40.50.970 2 191 3.1E-69 T 14-10-2018 C2I25_07005 05c0e198c196749b39eebabd0afe96f7 562 Gene3D G3DSA:3.40.50.970 370 561 2.1E-59 T 14-10-2018 C2I25_15390 249f9a4a6a3d2c90e77f973e347a58c9 301 SUPERFAMILY SSF103481 201 286 1.22E-12 T 14-10-2018 C2I25_15390 249f9a4a6a3d2c90e77f973e347a58c9 301 Pfam PF00892 EamA-like transporter family 7 138 3.8E-28 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_15390 249f9a4a6a3d2c90e77f973e347a58c9 301 Pfam PF00892 EamA-like transporter family 153 284 6.4E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_15390 249f9a4a6a3d2c90e77f973e347a58c9 301 SUPERFAMILY SSF103481 39 142 4.45E-17 T 14-10-2018 C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 SUPERFAMILY SSF51735 2 227 1.95E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 Gene3D G3DSA:3.40.50.720 1 236 5.8E-41 T 14-10-2018 C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_07175 b31a3aba62e5c041db19852e73cdcbfa 256 Pfam PF00106 short chain dehydrogenase 3 193 6.3E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23830 6d7b919139aac41a8d2191fe42444cb0 130 Gene3D G3DSA:3.10.180.10 1 130 6.8E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_23830 6d7b919139aac41a8d2191fe42444cb0 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 4.5E-14 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_23830 6d7b919139aac41a8d2191fe42444cb0 130 SUPERFAMILY SSF54593 1 127 1.61E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_26995 51fffd5619a0327747f721097748c807 745 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 713 743 9.4E-5 T 14-10-2018 C2I25_26995 51fffd5619a0327747f721097748c807 745 Gene3D G3DSA:2.60.40.10 337 430 7.9E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_26995 51fffd5619a0327747f721097748c807 745 Gene3D G3DSA:2.60.40.10 431 523 1.5E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_26995 51fffd5619a0327747f721097748c807 745 Gene3D G3DSA:2.60.40.10 524 615 1.5E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_26995 51fffd5619a0327747f721097748c807 745 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 45 327 1.5E-23 T 14-10-2018 IPR026588 Choice-of-anchor A domain C2I25_26995 51fffd5619a0327747f721097748c807 745 SUPERFAMILY SSF49478 343 412 2.75E-7 T 14-10-2018 C2I25_26995 51fffd5619a0327747f721097748c807 745 SUPERFAMILY SSF49478 626 694 4.32E-7 T 14-10-2018 C2I25_26995 51fffd5619a0327747f721097748c807 745 Gene3D G3DSA:2.60.40.10 620 717 1.1E-21 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_26995 51fffd5619a0327747f721097748c807 745 SUPERFAMILY SSF49478 532 600 1.18E-8 T 14-10-2018 C2I25_26995 51fffd5619a0327747f721097748c807 745 SUPERFAMILY SSF49478 438 506 1.22E-8 T 14-10-2018 C2I25_03300 b564efe0c4c4bd6b632d88d35fd3ac41 194 Pfam PF02698 DUF218 domain 44 169 1.5E-29 T 14-10-2018 IPR003848 Domain of unknown function DUF218 C2I25_03475 d248e78f9d3d51d58b9536689817b9f0 288 SMART SM00279 175 210 2.5E-14 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 C2I25_03475 d248e78f9d3d51d58b9536689817b9f0 288 Gene3D G3DSA:3.40.50.1010 4 277 3.3E-85 T 14-10-2018 C2I25_03475 d248e78f9d3d51d58b9536689817b9f0 288 SUPERFAMILY SSF47807 173 278 1.32E-26 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily C2I25_03475 d248e78f9d3d51d58b9536689817b9f0 288 SMART SM00475 2 263 3.2E-107 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 C2I25_03475 d248e78f9d3d51d58b9536689817b9f0 288 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 170 7.4E-51 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 C2I25_03475 d248e78f9d3d51d58b9536689817b9f0 288 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 259 1.8E-25 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 C2I25_03475 d248e78f9d3d51d58b9536689817b9f0 288 SUPERFAMILY SSF88723 1 172 3.05E-47 T 14-10-2018 IPR029060 PIN-like domain superfamily C2I25_03475 d248e78f9d3d51d58b9536689817b9f0 288 Gene3D G3DSA:1.10.150.20 176 248 3.3E-85 T 14-10-2018 C2I25_09125 38f4d8ae10c08aa794dcdcb21aa1ad25 203 Pfam PF02659 Putative manganese efflux pump 118 200 1.6E-10 T 14-10-2018 IPR003810 Putative manganese efflux pump C2I25_09125 38f4d8ae10c08aa794dcdcb21aa1ad25 203 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 8 201 2.2E-45 T 14-10-2018 IPR014205 Sporulation protein YtaF C2I25_07375 b980a399a93b48a109569989147a4524 101 SUPERFAMILY SSF52794 1 98 6.41E-33 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I25_07375 b980a399a93b48a109569989147a4524 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 1.6E-19 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I25_07375 b980a399a93b48a109569989147a4524 101 Gene3D G3DSA:3.40.50.2300 1 101 7.0E-34 T 14-10-2018 C2I25_27940 2ceedeaaaab62744822da54f10d94b3a 49 Pfam PF09388 Spo0E like sporulation regulatory protein 6 46 1.7E-13 T 14-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I25_27940 2ceedeaaaab62744822da54f10d94b3a 49 Gene3D G3DSA:1.20.58.990 1 49 4.4E-19 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_27940 2ceedeaaaab62744822da54f10d94b3a 49 SUPERFAMILY SSF140500 1 48 1.7E-14 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_08170 9ee6ab600d2e9ee55c9a9b9b261b274d 131 SUPERFAMILY SSF102546 1 131 3.66E-45 T 14-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 C2I25_08170 9ee6ab600d2e9ee55c9a9b9b261b274d 131 Gene3D G3DSA:3.40.1650.10 8 127 1.9E-37 T 14-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 C2I25_08170 9ee6ab600d2e9ee55c9a9b9b261b274d 131 Pfam PF05025 RbsD / FucU transport protein family 1 130 5.0E-48 T 14-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 C2I25_08170 9ee6ab600d2e9ee55c9a9b9b261b274d 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 32.699 T 14-10-2018 IPR023064 D-ribose pyranase GO:0016872 C2I25_20370 81ca06db1c987b799413bd48e3f5bc5b 259 PIRSF PIRSF011572 1 257 1.0E-122 T 14-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 C2I25_20370 81ca06db1c987b799413bd48e3f5bc5b 259 Gene3D G3DSA:3.30.450.40 1 159 7.1E-68 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_20370 81ca06db1c987b799413bd48e3f5bc5b 259 Gene3D G3DSA:1.10.10.10 160 259 6.9E-47 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20370 81ca06db1c987b799413bd48e3f5bc5b 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 5.4E-124 T 14-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 C2I25_20370 81ca06db1c987b799413bd48e3f5bc5b 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 149.326 T 14-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 C2I25_20370 81ca06db1c987b799413bd48e3f5bc5b 259 Pfam PF06018 CodY GAF-like domain 2 178 3.2E-81 T 14-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 C2I25_20370 81ca06db1c987b799413bd48e3f5bc5b 259 SUPERFAMILY SSF46785 167 256 1.4E-42 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_20370 81ca06db1c987b799413bd48e3f5bc5b 259 Pfam PF08222 CodY helix-turn-helix domain 197 257 1.5E-38 T 14-10-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal C2I25_20595 d5ebca43c4ec5c88e37652cf65bbed93 261 Pfam PF11868 Protein of unknown function (DUF3388) 70 259 5.0E-107 T 14-10-2018 IPR024514 Domain of unknown function DUF3388 C2I25_20595 d5ebca43c4ec5c88e37652cf65bbed93 261 PIRSF PIRSF021288 1 260 1.2E-142 T 14-10-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain C2I25_20595 d5ebca43c4ec5c88e37652cf65bbed93 261 SUPERFAMILY SSF55021 3 73 4.58E-9 T 14-10-2018 C2I25_20595 d5ebca43c4ec5c88e37652cf65bbed93 261 Gene3D G3DSA:3.30.70.260 8 73 2.2E-5 T 14-10-2018 C2I25_15705 a3eb8bb90b11f16dd601f90237261427 107 SMART SM00418 9 87 8.6E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_15705 a3eb8bb90b11f16dd601f90237261427 107 Gene3D G3DSA:1.10.10.10 2 107 5.2E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15705 a3eb8bb90b11f16dd601f90237261427 107 Pfam PF12840 Helix-turn-helix domain 9 67 1.2E-11 T 14-10-2018 C2I25_15705 a3eb8bb90b11f16dd601f90237261427 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 2.8E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_15705 a3eb8bb90b11f16dd601f90237261427 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.8E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_15705 a3eb8bb90b11f16dd601f90237261427 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 2.8E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_15705 a3eb8bb90b11f16dd601f90237261427 107 SUPERFAMILY SSF46785 8 93 3.91E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_03900 161c6798f4e0f362a6409bf09647306b 70 Pfam PF14140 YpzI-like protein 27 68 3.4E-26 T 14-10-2018 IPR025414 YpzI-like protein C2I25_25245 f45648d18dad9df667aacf2b81338b3c 332 SUPERFAMILY SSF56112 15 307 1.66E-42 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_25245 f45648d18dad9df667aacf2b81338b3c 332 Pfam PF01636 Phosphotransferase enzyme family 34 267 3.6E-19 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_25245 f45648d18dad9df667aacf2b81338b3c 332 Gene3D G3DSA:3.90.1200.10 119 322 1.1E-20 T 14-10-2018 C2I25_25245 f45648d18dad9df667aacf2b81338b3c 332 Gene3D G3DSA:3.30.200.20 4 113 6.8E-8 T 14-10-2018 C2I25_08495 aa9c58a3ff4af58cfd91c9ae9b0e1a0d 487 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 10 465 6.5E-179 T 14-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 C2I25_08495 aa9c58a3ff4af58cfd91c9ae9b0e1a0d 487 PIRSF PIRSF000484 2 480 3.5E-157 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 C2I25_08495 aa9c58a3ff4af58cfd91c9ae9b0e1a0d 487 Gene3D G3DSA:3.20.20.70 151 318 2.0E-204 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_08495 aa9c58a3ff4af58cfd91c9ae9b0e1a0d 487 SUPERFAMILY SSF54675 5 138 3.2E-48 T 14-10-2018 C2I25_08495 aa9c58a3ff4af58cfd91c9ae9b0e1a0d 487 SUPERFAMILY SSF51690 139 478 8.24E-131 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 C2I25_08495 aa9c58a3ff4af58cfd91c9ae9b0e1a0d 487 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 155 336 4.0E-13 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 C2I25_08495 aa9c58a3ff4af58cfd91c9ae9b0e1a0d 487 Gene3D G3DSA:3.20.140.10 11 470 2.0E-204 T 14-10-2018 C2I25_25330 2e55c01005835a8415f8fee04e977804 108 Pfam PF12986 Domain of unknown function (DUF3870) 8 99 7.6E-33 T 14-10-2018 IPR024617 Domain of unknown function DUF3870 C2I25_22385 e632bd0cf7c4ee74c943abd9f4b43bf0 116 Pfam PF08830 Protein of unknown function (DUF1806) 8 115 1.6E-53 T 14-10-2018 IPR014934 Protein of unknown function DUF1806 C2I25_22385 e632bd0cf7c4ee74c943abd9f4b43bf0 116 Gene3D G3DSA:2.70.180.10 2 116 1.1E-49 T 14-10-2018 IPR036492 Hypothetical protein YojF superfamily C2I25_22385 e632bd0cf7c4ee74c943abd9f4b43bf0 116 SUPERFAMILY SSF89442 8 116 6.54E-53 T 14-10-2018 IPR036492 Hypothetical protein YojF superfamily C2I25_27195 e465c060198d128469291f943f8b39a7 586 SUPERFAMILY SSF56519 32 214 3.66E-32 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_27195 e465c060198d128469291f943f8b39a7 586 SUPERFAMILY SSF56601 169 574 2.14E-58 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_27195 e465c060198d128469291f943f8b39a7 586 Pfam PF00905 Penicillin binding protein transpeptidase domain 241 567 1.7E-43 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_27195 e465c060198d128469291f943f8b39a7 586 Gene3D G3DSA:3.90.1310.30 30 211 9.2E-32 T 14-10-2018 C2I25_27195 e465c060198d128469291f943f8b39a7 586 Pfam PF03717 Penicillin-binding Protein dimerisation domain 37 202 3.6E-32 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_27195 e465c060198d128469291f943f8b39a7 586 Gene3D G3DSA:3.40.710.10 212 584 1.0E-68 T 14-10-2018 C2I25_20160 fc54de1fc66c7b9ad5ef0e323d6a46a9 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 366 1.3E-72 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I25_20160 fc54de1fc66c7b9ad5ef0e323d6a46a9 401 Gene3D G3DSA:3.40.50.1950 1 184 5.1E-59 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I25_20160 fc54de1fc66c7b9ad5ef0e323d6a46a9 401 Pfam PF02441 Flavoprotein 5 177 1.4E-44 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 C2I25_20160 fc54de1fc66c7b9ad5ef0e323d6a46a9 401 SUPERFAMILY SSF52507 1 179 1.09E-59 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I25_20160 fc54de1fc66c7b9ad5ef0e323d6a46a9 401 SUPERFAMILY SSF102645 183 396 3.66E-77 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I25_20160 fc54de1fc66c7b9ad5ef0e323d6a46a9 401 Gene3D G3DSA:3.40.50.10300 185 401 5.3E-92 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I25_20160 fc54de1fc66c7b9ad5ef0e323d6a46a9 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 392 3.3E-152 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 C2I25_25135 313ca712d95f4eb6d1facfc96475ec69 80 Pfam PF04226 Transglycosylase associated protein 31 75 7.1E-12 T 14-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 C2I25_12635 aeb2b6948799cd30e4f3e28454757906 168 Hamap MF_01398 ATP synthase subunit b [atpF]. 9 146 13.273 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 C2I25_12635 aeb2b6948799cd30e4f3e28454757906 168 SUPERFAMILY SSF81573 71 129 2.09E-7 T 14-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily C2I25_12635 aeb2b6948799cd30e4f3e28454757906 168 Pfam PF00430 ATP synthase B/B' CF(0) 14 145 1.4E-37 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 C2I25_12635 aeb2b6948799cd30e4f3e28454757906 168 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 21 164 3.8E-39 T 14-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 C2I25_25660 e5e24a4d674e18f315f0ef68a54c1656 159 Gene3D G3DSA:3.30.428.10 2 156 2.9E-31 T 14-10-2018 IPR036265 HIT-like superfamily C2I25_25660 e5e24a4d674e18f315f0ef68a54c1656 159 Pfam PF01230 HIT domain 27 114 6.4E-8 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_25660 e5e24a4d674e18f315f0ef68a54c1656 159 SUPERFAMILY SSF54197 9 151 4.02E-30 T 14-10-2018 IPR036265 HIT-like superfamily C2I25_24050 075f7b0d16c0e5396386474c39a182c1 214 SUPERFAMILY SSF52499 3 204 3.92E-49 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_24050 075f7b0d16c0e5396386474c39a182c1 214 Gene3D G3DSA:3.40.50.850 2 204 3.1E-47 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_24050 075f7b0d16c0e5396386474c39a182c1 214 Pfam PF00857 Isochorismatase family 12 163 1.8E-24 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_24515 e1da3f09d1b598f864583bebaedaa4f1 180 Gene3D G3DSA:3.40.630.30 3 180 2.1E-52 T 14-10-2018 C2I25_24515 e1da3f09d1b598f864583bebaedaa4f1 180 Pfam PF13302 Acetyltransferase (GNAT) domain 10 150 8.3E-34 T 14-10-2018 IPR000182 GNAT domain C2I25_24515 e1da3f09d1b598f864583bebaedaa4f1 180 SUPERFAMILY SSF55729 3 175 5.59E-55 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01220 7558ec39b881c6e090f195303b832e64 471 SMART SM00345 19 78 6.7E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01220 7558ec39b881c6e090f195303b832e64 471 Gene3D G3DSA:1.10.10.10 1 86 1.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01220 7558ec39b881c6e090f195303b832e64 471 Pfam PF00155 Aminotransferase class I and II 117 414 2.7E-15 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_01220 7558ec39b881c6e090f195303b832e64 471 SUPERFAMILY SSF46785 8 84 2.81E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01220 7558ec39b881c6e090f195303b832e64 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 1.4E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01220 7558ec39b881c6e090f195303b832e64 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 1.4E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01220 7558ec39b881c6e090f195303b832e64 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 6.1E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_01220 7558ec39b881c6e090f195303b832e64 471 Gene3D G3DSA:3.40.640.10 91 456 1.6E-117 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_01220 7558ec39b881c6e090f195303b832e64 471 SUPERFAMILY SSF53383 85 462 2.14E-78 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_12245 27f29765cda31cb9dda7e2d8d9905793 230 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 79 5.2E-45 T 14-10-2018 IPR014243 Transcription factor, RsfA C2I25_12245 27f29765cda31cb9dda7e2d8d9905793 230 Pfam PF13921 Myb-like DNA-binding domain 8 57 3.1E-5 T 14-10-2018 C2I25_07305 763d4d630ced348b9898682492af781b 91 Pfam PF12652 CotJB protein 15 90 5.2E-29 T 14-10-2018 IPR024207 Spore coat assembly protein CotJB, domain C2I25_07305 763d4d630ced348b9898682492af781b 91 PIRSF PIRSF010606 3 91 1.0E-44 T 14-10-2018 IPR016571 Spore coat assembly protein CotJB C2I25_08045 b2b592a74f634741d8aeef5c0e650617 461 Gene3D G3DSA:1.20.1250.20 233 461 5.1E-59 T 14-10-2018 C2I25_08045 b2b592a74f634741d8aeef5c0e650617 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 243 460 2.5E-44 T 14-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 C2I25_08045 b2b592a74f634741d8aeef5c0e650617 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 226 4.1E-57 T 14-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 C2I25_08045 b2b592a74f634741d8aeef5c0e650617 461 Gene3D G3DSA:1.20.1250.20 9 232 2.3E-69 T 14-10-2018 C2I25_08045 b2b592a74f634741d8aeef5c0e650617 461 Pfam PF00854 POT family 92 214 1.2E-28 T 14-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 C2I25_08045 b2b592a74f634741d8aeef5c0e650617 461 Pfam PF00854 POT family 245 428 1.9E-36 T 14-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 C2I25_08045 b2b592a74f634741d8aeef5c0e650617 461 SUPERFAMILY SSF103473 10 458 8.63E-46 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_08045 b2b592a74f634741d8aeef5c0e650617 461 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 154 166 - T 14-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 C2I25_12670 1f4f396987c2ea8c1cea8817a6743277 214 Pfam PF06161 Protein of unknown function (DUF975) 2 127 1.8E-14 T 14-10-2018 IPR010380 Protein of unknown function DUF975 C2I25_12670 1f4f396987c2ea8c1cea8817a6743277 214 Pfam PF06161 Protein of unknown function (DUF975) 120 207 1.1E-28 T 14-10-2018 IPR010380 Protein of unknown function DUF975 C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 381 2.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 Gene3D G3DSA:3.30.565.10 233 384 2.0E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 Pfam PF00512 His Kinase A (phospho-acceptor) domain 160 225 6.1E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 Gene3D G3DSA:1.10.287.130 104 223 2.1E-21 T 14-10-2018 C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 324 1.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 363 1.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 338 1.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 SMART SM00388 160 227 9.5E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 SUPERFAMILY SSF47384 145 227 4.12E-19 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 SMART SM00387 273 384 1.5E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_27060 ab02d5afc89ed960354bf881ac8a083e 385 SUPERFAMILY SSF55874 216 380 4.58E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_00160 87c89f2428f6625a639c6feb75b397e9 182 Pfam PF00857 Isochorismatase family 4 176 3.4E-37 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_00160 87c89f2428f6625a639c6feb75b397e9 182 Gene3D G3DSA:3.40.50.850 1 182 4.1E-52 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_00160 87c89f2428f6625a639c6feb75b397e9 182 SUPERFAMILY SSF52499 2 176 1.24E-49 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_05835 4b98d2c982b8fefe153933cdbb0a5df5 372 Pfam PF13800 Sigma factor regulator N-terminal 65 151 2.5E-13 T 14-10-2018 IPR029101 Sigma factor regulator, N-terminal C2I25_05835 4b98d2c982b8fefe153933cdbb0a5df5 372 Pfam PF13791 Sigma factor regulator C-terminal 205 362 2.4E-41 T 14-10-2018 IPR025672 Sigma factor regulator C-terminal domain C2I25_05835 4b98d2c982b8fefe153933cdbb0a5df5 372 Pfam PF13490 Putative zinc-finger 3 36 6.7E-5 T 14-10-2018 IPR027383 Putative zinc-finger C2I25_19750 f4f253aaa684ab67e4484813ff911bb7 392 Pfam PF01098 Cell cycle protein 13 368 1.1E-106 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19750 f4f253aaa684ab67e4484813ff911bb7 392 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 325 349 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_20650 46c432b56cd59592d215feec3fa5302e 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 1.5E-32 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I25_20650 46c432b56cd59592d215feec3fa5302e 288 Gene3D G3DSA:3.40.50.970 70 242 9.9E-30 T 14-10-2018 C2I25_20650 46c432b56cd59592d215feec3fa5302e 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 264 7.9E-23 T 14-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal C2I25_20650 46c432b56cd59592d215feec3fa5302e 288 SUPERFAMILY SSF52518 12 286 1.52E-79 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_20650 46c432b56cd59592d215feec3fa5302e 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 274 1.9E-97 T 14-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate C2I25_09795 b102d5e122a748dc0583e849b1033a37 155 Pfam PF13787 Protein of unknown function with HXXEE motif 10 114 5.8E-13 T 14-10-2018 IPR025671 Protein of unknown function with HXXEE motif C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 SUPERFAMILY SSF52540 44 271 6.42E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 394 1.2E-151 T 14-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 Pfam PF00005 ABC transporter 46 193 1.1E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 Pfam PF00571 CBS domain 294 329 0.0064 T 14-10-2018 IPR000644 CBS domain C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 Pfam PF00571 CBS domain 338 390 5.6E-4 T 14-10-2018 IPR000644 CBS domain C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 SUPERFAMILY SSF54631 280 392 1.21E-20 T 14-10-2018 C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 Gene3D G3DSA:3.10.580.10 287 396 2.5E-13 T 14-10-2018 C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 SMART SM00116 283 331 0.33 T 14-10-2018 IPR000644 CBS domain C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 SMART SM00116 343 390 0.0032 T 14-10-2018 IPR000644 CBS domain C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 Gene3D G3DSA:3.40.50.300 32 286 1.7E-77 T 14-10-2018 C2I25_25640 44c108ae396dcf4a09d78d393503a6ea 401 SMART SM00382 54 243 4.8E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 2.3E-26 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 SUPERFAMILY SSF55920 83 348 8.77E-85 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 Gene3D G3DSA:3.90.230.10 126 353 1.4E-88 T 14-10-2018 C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 SUPERFAMILY SSF53092 2 125 9.42E-24 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 Pfam PF00557 Metallopeptidase family M24 136 336 7.1E-68 T 14-10-2018 IPR000994 Peptidase M24 C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 6.3E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 6.3E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 185 198 6.3E-7 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I25_18325 1e3df6466731b5b8eaa45fe3077c9895 353 Gene3D G3DSA:3.40.350.10 1 125 3.7E-36 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I25_23330 1f7aea196d30d68e1ff8eb121fb6e971 181 Pfam PF12840 Helix-turn-helix domain 6 64 5.8E-9 T 14-10-2018 C2I25_23330 1f7aea196d30d68e1ff8eb121fb6e971 181 Gene3D G3DSA:1.20.1270.400 87 180 1.8E-8 T 14-10-2018 C2I25_23330 1f7aea196d30d68e1ff8eb121fb6e971 181 SUPERFAMILY SSF46785 6 150 7.49E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23330 1f7aea196d30d68e1ff8eb121fb6e971 181 SMART SM00418 3 87 0.0051 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_23330 1f7aea196d30d68e1ff8eb121fb6e971 181 Gene3D G3DSA:1.10.10.10 1 82 2.7E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02860 1aa9d7adccd7ee7c22fad3ffbf33b333 136 SMART SM00347 16 116 2.7E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_02860 1aa9d7adccd7ee7c22fad3ffbf33b333 136 Gene3D G3DSA:1.10.10.10 1 133 3.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02860 1aa9d7adccd7ee7c22fad3ffbf33b333 136 SUPERFAMILY SSF46785 6 128 1.1E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02860 1aa9d7adccd7ee7c22fad3ffbf33b333 136 Pfam PF01047 MarR family 23 81 2.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_12250 e6ef86cb16650934c1509375b32803a9 74 Hamap MF_01863 UPF0741 protein . 1 74 28.737 T 14-10-2018 IPR020880 Protein of unknown function UPF0741 C2I25_12250 e6ef86cb16650934c1509375b32803a9 74 Pfam PF07293 Protein of unknown function (DUF1450) 7 73 5.9E-11 T 14-10-2018 IPR009910 Protein of unknown function DUF1450 C2I25_20970 514fd08f25f532e1341c6d422a009697 74 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 31.451 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I25_20970 514fd08f25f532e1341c6d422a009697 74 Gene3D G3DSA:2.30.30.100 1 74 6.8E-35 T 14-10-2018 C2I25_20970 514fd08f25f532e1341c6d422a009697 74 Pfam PF17209 Hfq protein 7 69 5.4E-33 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I25_20970 514fd08f25f532e1341c6d422a009697 74 SUPERFAMILY SSF50182 6 65 2.25E-24 T 14-10-2018 IPR010920 LSM domain superfamily C2I25_20970 514fd08f25f532e1341c6d422a009697 74 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 2.7E-32 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I25_13640 e2b4cc4c81322ce720ec0826fdbb8d8f 121 Pfam PF06486 Protein of unknown function (DUF1093) 27 105 9.3E-15 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_13640 e2b4cc4c81322ce720ec0826fdbb8d8f 121 Gene3D G3DSA:2.40.50.480 26 121 5.9E-14 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_13640 e2b4cc4c81322ce720ec0826fdbb8d8f 121 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 113 4.3E-8 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_13640 e2b4cc4c81322ce720ec0826fdbb8d8f 121 SUPERFAMILY SSF159121 25 118 6.8E-19 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_10035 016a2b4cc1006f1e48c68dc3817e66bc 319 SUPERFAMILY SSF51730 45 305 2.2E-56 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like C2I25_10035 016a2b4cc1006f1e48c68dc3817e66bc 319 Pfam PF01619 Proline dehydrogenase 54 297 1.9E-18 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 C2I25_10035 016a2b4cc1006f1e48c68dc3817e66bc 319 PIRSF PIRSF000196 9 311 9.0E-99 T 14-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 C2I25_10035 016a2b4cc1006f1e48c68dc3817e66bc 319 Gene3D G3DSA:3.20.20.530 28 309 2.2E-65 T 14-10-2018 C2I25_25665 aa7a8a17c20cb432aadf8fbcdfbda105 276 SUPERFAMILY SSF81606 46 256 1.28E-12 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_25665 aa7a8a17c20cb432aadf8fbcdfbda105 276 Gene3D G3DSA:3.60.40.10 33 264 6.3E-13 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_25665 aa7a8a17c20cb432aadf8fbcdfbda105 276 Pfam PF13672 Protein phosphatase 2C 38 235 1.7E-19 T 14-10-2018 C2I25_09665 de3759cc2533a4d8a525cc7cf433fef2 369 SMART SM00922 142 239 1.3E-27 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal C2I25_09665 de3759cc2533a4d8a525cc7cf433fef2 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 124 8.8E-24 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain C2I25_09665 de3759cc2533a4d8a525cc7cf433fef2 369 SUPERFAMILY SSF54826 1 125 1.13E-36 T 14-10-2018 C2I25_09665 de3759cc2533a4d8a525cc7cf433fef2 369 SUPERFAMILY SSF51604 112 363 3.28E-69 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I25_09665 de3759cc2533a4d8a525cc7cf433fef2 369 Gene3D G3DSA:3.20.20.120 116 350 2.5E-147 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I25_09665 de3759cc2533a4d8a525cc7cf433fef2 369 Pfam PF13378 Enolase C-terminal domain-like 145 356 5.2E-49 T 14-10-2018 IPR029065 Enolase C-terminal domain-like C2I25_09665 de3759cc2533a4d8a525cc7cf433fef2 369 Gene3D G3DSA:3.30.390.10 1 356 2.5E-147 T 14-10-2018 IPR029017 Enolase-like, N-terminal C2I25_22075 fd934bfd7c60202f3813617316987dad 347 Gene3D G3DSA:1.10.3290.10 20 287 9.6E-33 T 14-10-2018 IPR036597 Fido-like domain superfamily C2I25_22075 fd934bfd7c60202f3813617316987dad 347 Pfam PF02661 Fic/DOC family 109 215 1.8E-12 T 14-10-2018 IPR003812 Fido domain C2I25_22075 fd934bfd7c60202f3813617316987dad 347 SUPERFAMILY SSF140931 93 286 4.84E-25 T 14-10-2018 IPR036597 Fido-like domain superfamily C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 SUPERFAMILY SSF56784 2 214 8.14E-51 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 7.3E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 7.3E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 7.3E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 7.3E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 Gene3D G3DSA:3.40.50.1000 3 201 1.1E-52 T 14-10-2018 IPR023214 HAD superfamily C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 183 5.7E-44 T 14-10-2018 C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 Gene3D G3DSA:1.10.150.240 15 83 1.1E-52 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_18300 baf2a9c3db5c295a476413376de69ba5 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 72 183 1.5E-16 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_12845 b64b9a6439226b265b621d0336088267 423 SUPERFAMILY SSF53756 5 402 2.58E-40 T 14-10-2018 C2I25_12845 b64b9a6439226b265b621d0336088267 423 Gene3D G3DSA:3.40.50.2000 224 402 1.5E-37 T 14-10-2018 C2I25_12845 b64b9a6439226b265b621d0336088267 423 Pfam PF00534 Glycosyl transferases group 1 235 393 4.2E-31 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 C2I25_12845 b64b9a6439226b265b621d0336088267 423 Gene3D G3DSA:3.40.50.2000 129 405 1.5E-37 T 14-10-2018 C2I25_26535 462919cd900425adfb1eb664bfdb458c 310 SMART SM00644 13 154 3.8E-33 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_26535 462919cd900425adfb1eb664bfdb458c 310 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 22 139 4.8E-18 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_26535 462919cd900425adfb1eb664bfdb458c 310 Gene3D G3DSA:2.30.30.40 245 309 1.6E-9 T 14-10-2018 C2I25_26535 462919cd900425adfb1eb664bfdb458c 310 Gene3D G3DSA:3.40.80.10 1 162 1.4E-53 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_26535 462919cd900425adfb1eb664bfdb458c 310 SUPERFAMILY SSF55846 4 156 4.45E-53 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_26535 462919cd900425adfb1eb664bfdb458c 310 Gene3D G3DSA:2.30.30.40 182 237 1.1E-8 T 14-10-2018 C2I25_26535 462919cd900425adfb1eb664bfdb458c 310 SMART SM00287 176 230 0.23 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_26535 462919cd900425adfb1eb664bfdb458c 310 SMART SM00287 251 309 0.022 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_01940 17701c2603496209ad12e94373072251 139 SUPERFAMILY SSF55331 2 132 1.62E-34 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_01940 17701c2603496209ad12e94373072251 139 Pfam PF14552 Tautomerase enzyme 39 123 1.3E-21 T 14-10-2018 IPR037479 Tautomerase, MSAD family C2I25_01940 17701c2603496209ad12e94373072251 139 Gene3D G3DSA:3.30.429.10 2 137 2.6E-39 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_20530 b91d65a6fe61b94ceebc9360113518cd 249 SUPERFAMILY SSF52096 44 230 2.57E-36 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_20530 b91d65a6fe61b94ceebc9360113518cd 249 Pfam PF00574 Clp protease 46 222 5.2E-34 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA C2I25_20530 b91d65a6fe61b94ceebc9360113518cd 249 Gene3D G3DSA:3.90.226.10 46 223 2.0E-29 T 14-10-2018 C2I25_06220 1e43282ef4b5aadb5632dd991bd3cad3 778 SUPERFAMILY SSF52540 201 758 5.94E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_06220 1e43282ef4b5aadb5632dd991bd3cad3 778 Pfam PF13245 AAA domain 214 579 5.0E-11 T 14-10-2018 C2I25_06220 1e43282ef4b5aadb5632dd991bd3cad3 778 Pfam PF13538 UvrD-like helicase C-terminal domain 710 753 4.3E-8 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain C2I25_06220 1e43282ef4b5aadb5632dd991bd3cad3 778 Gene3D G3DSA:3.40.50.300 202 433 1.7E-10 T 14-10-2018 C2I25_06220 1e43282ef4b5aadb5632dd991bd3cad3 778 Gene3D G3DSA:3.40.50.300 450 594 5.8E-9 T 14-10-2018 C2I25_06220 1e43282ef4b5aadb5632dd991bd3cad3 778 Gene3D G3DSA:3.40.50.300 605 776 6.6E-56 T 14-10-2018 C2I25_11690 07ca46b881b089c308bb13184c2821e3 253 Gene3D G3DSA:3.40.50.300 1 252 4.0E-84 T 14-10-2018 C2I25_11690 07ca46b881b089c308bb13184c2821e3 253 Pfam PF13614 AAA domain 2 178 1.0E-74 T 14-10-2018 IPR025669 AAA domain C2I25_11690 07ca46b881b089c308bb13184c2821e3 253 PIRSF PIRSF009320 54 251 6.0E-9 T 14-10-2018 C2I25_11690 07ca46b881b089c308bb13184c2821e3 253 PIRSF PIRSF009320 2 87 8.3E-15 T 14-10-2018 C2I25_11690 07ca46b881b089c308bb13184c2821e3 253 SUPERFAMILY SSF52540 1 250 1.87E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_06645 e8acbc0aa81a4573bfcc455d7c683891 460 Pfam PF12697 Alpha/beta hydrolase family 194 424 3.3E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_06645 e8acbc0aa81a4573bfcc455d7c683891 460 SUPERFAMILY SSF53474 147 457 3.05E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_06645 e8acbc0aa81a4573bfcc455d7c683891 460 Gene3D G3DSA:3.40.50.1820 171 434 6.4E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_12115 7c328b823617485c941c6b670f8590c3 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 SMART SM00421 152 209 7.1E-26 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 Gene3D G3DSA:3.40.50.12740 3 215 1.6E-75 T 14-10-2018 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 SUPERFAMILY SSF46894 146 215 1.39E-22 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 SMART SM00448 3 116 2.6E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 209 2.4E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 Pfam PF00072 Response regulator receiver domain 5 117 5.9E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_12115 7c328b823617485c941c6b670f8590c3 215 SUPERFAMILY SSF52172 2 134 1.42E-37 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 SUPERFAMILY SSF81296 41 210 1.82E-57 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 Gene3D G3DSA:2.10.10.20 408 455 9.2E-8 T 14-10-2018 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 SUPERFAMILY SSF51055 407 441 4.71E-6 T 14-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 SMART SM00060 314 391 1.1E-6 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 SMART SM00060 220 293 3.5E-8 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 41 207 5.5E-39 T 14-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 Gene3D G3DSA:2.70.50.50 41 210 4.4E-68 T 14-10-2018 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 Pfam PF00041 Fibronectin type III domain 221 297 1.4E-5 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 Pfam PF00041 Fibronectin type III domain 316 391 1.1E-5 T 14-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 SUPERFAMILY SSF49265 219 403 4.57E-25 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 SMART SM00495 409 455 1.6E-4 T 14-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 Gene3D G3DSA:2.60.40.10 312 402 3.5E-20 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_22080 217a35f2a48aede1407cd70c1b7b2baa 458 Gene3D G3DSA:2.60.40.10 217 304 2.8E-22 T 14-10-2018 IPR013783 Immunoglobulin-like fold C2I25_13360 43ccad7dec40447bbccd3f6346d2e9f3 352 Pfam PF03601 Conserved hypothetical protein 698 29 330 2.4E-84 T 14-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 C2I25_03255 533aa05e759d0411846d2b2b13b16e70 155 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 124 1.3E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_03255 533aa05e759d0411846d2b2b13b16e70 155 Gene3D G3DSA:3.10.180.10 5 154 1.4E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_03255 533aa05e759d0411846d2b2b13b16e70 155 SUPERFAMILY SSF54593 1 129 1.32E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_06685 eff9a9166b1049e4b8bf048bf73f6ab0 491 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 440 3.7E-100 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_06685 eff9a9166b1049e4b8bf048bf73f6ab0 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 1.1E-5 T 14-10-2018 C2I25_06685 eff9a9166b1049e4b8bf048bf73f6ab0 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 311 335 1.1E-5 T 14-10-2018 C2I25_06685 eff9a9166b1049e4b8bf048bf73f6ab0 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 1.1E-5 T 14-10-2018 C2I25_06685 eff9a9166b1049e4b8bf048bf73f6ab0 491 Gene3D G3DSA:1.20.1250.20 270 483 2.1E-20 T 14-10-2018 C2I25_06685 eff9a9166b1049e4b8bf048bf73f6ab0 491 Gene3D G3DSA:1.20.1720.10 23 236 2.6E-34 T 14-10-2018 C2I25_06685 eff9a9166b1049e4b8bf048bf73f6ab0 491 Pfam PF07690 Major Facilitator Superfamily 27 417 3.1E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_06685 eff9a9166b1049e4b8bf048bf73f6ab0 491 SUPERFAMILY SSF103473 16 480 1.44E-60 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_11890 54e3facf79a0a51ae9ba924ba3123da8 568 Pfam PF00664 ABC transporter transmembrane region 22 288 1.4E-40 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_11890 54e3facf79a0a51ae9ba924ba3123da8 568 SMART SM00382 355 550 3.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_11890 54e3facf79a0a51ae9ba924ba3123da8 568 SUPERFAMILY SSF52540 324 565 7.8E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11890 54e3facf79a0a51ae9ba924ba3123da8 568 Gene3D G3DSA:1.20.1560.10 9 314 2.7E-68 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_11890 54e3facf79a0a51ae9ba924ba3123da8 568 Pfam PF00005 ABC transporter 346 497 3.1E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_11890 54e3facf79a0a51ae9ba924ba3123da8 568 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_11890 54e3facf79a0a51ae9ba924ba3123da8 568 Gene3D G3DSA:3.40.50.300 315 567 1.3E-79 T 14-10-2018 C2I25_11890 54e3facf79a0a51ae9ba924ba3123da8 568 SUPERFAMILY SSF90123 14 313 1.15E-63 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_08005 cf10f7d680ca57eea7324f6acc4b6d21 145 SUPERFAMILY SSF55729 24 133 1.95E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_08005 cf10f7d680ca57eea7324f6acc4b6d21 145 Pfam PF00583 Acetyltransferase (GNAT) family 34 123 1.5E-8 T 14-10-2018 IPR000182 GNAT domain C2I25_08005 cf10f7d680ca57eea7324f6acc4b6d21 145 Gene3D G3DSA:3.40.630.30 1 145 8.1E-32 T 14-10-2018 C2I25_17875 beac14d8a632f17b39e1a245e0bd91e8 256 SMART SM00382 29 214 6.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_17875 beac14d8a632f17b39e1a245e0bd91e8 256 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_17875 beac14d8a632f17b39e1a245e0bd91e8 256 Pfam PF00005 ABC transporter 20 168 3.2E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_17875 beac14d8a632f17b39e1a245e0bd91e8 256 SUPERFAMILY SSF52540 2 227 5.94E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17875 beac14d8a632f17b39e1a245e0bd91e8 256 Gene3D G3DSA:3.40.50.300 1 250 1.5E-66 T 14-10-2018 C2I25_04965 a007d4d6c9c4d06b807bd3475f467da6 730 SUPERFAMILY SSF82866 499 719 1.23E-32 T 14-10-2018 C2I25_04965 a007d4d6c9c4d06b807bd3475f467da6 730 SUPERFAMILY SSF82866 184 341 6.02E-31 T 14-10-2018 C2I25_04965 a007d4d6c9c4d06b807bd3475f467da6 730 Pfam PF03176 MMPL family 396 727 2.2E-38 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I25_04965 a007d4d6c9c4d06b807bd3475f467da6 730 Pfam PF03176 MMPL family 59 366 5.3E-47 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I25_04965 a007d4d6c9c4d06b807bd3475f467da6 730 Gene3D G3DSA:1.20.1640.10 505 718 1.5E-5 T 14-10-2018 C2I25_04965 a007d4d6c9c4d06b807bd3475f467da6 730 Gene3D G3DSA:1.20.1640.10 153 351 1.8E-11 T 14-10-2018 C2I25_21180 a4b0bbbbe61d79604156d0aa19f295d9 235 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 3.0E-63 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 C2I25_28390 e3f53c3d482f3e039b53ca29c5ef5e76 104 SUPERFAMILY SSF52833 2 103 2.76E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_28390 e3f53c3d482f3e039b53ca29c5ef5e76 104 Gene3D G3DSA:3.40.30.10 1 103 1.1E-26 T 14-10-2018 C2I25_28390 e3f53c3d482f3e039b53ca29c5ef5e76 104 Pfam PF00085 Thioredoxin 5 102 4.4E-18 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I25_07995 abb090adb58142713d386827219580b1 609 Pfam PF00999 Sodium/hydrogen exchanger family 12 385 5.3E-74 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I25_07995 abb090adb58142713d386827219580b1 609 Pfam PF02254 TrkA-N domain 399 508 1.8E-9 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I25_07995 abb090adb58142713d386827219580b1 609 Gene3D G3DSA:1.20.1530.20 3 396 2.0E-70 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily C2I25_07995 abb090adb58142713d386827219580b1 609 Gene3D G3DSA:3.40.50.720 397 529 1.9E-16 T 14-10-2018 C2I25_07995 abb090adb58142713d386827219580b1 609 SUPERFAMILY SSF116726 538 608 5.62E-13 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_07995 abb090adb58142713d386827219580b1 609 Pfam PF02080 TrkA-C domain 542 608 2.0E-11 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I25_07995 abb090adb58142713d386827219580b1 609 SUPERFAMILY SSF51735 396 539 1.53E-15 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_07995 abb090adb58142713d386827219580b1 609 Gene3D G3DSA:3.30.70.1450 530 609 1.4E-18 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_18825 d17c384cd0668d2b6050025a0f152058 259 SUPERFAMILY SSF52266 56 254 3.24E-30 T 14-10-2018 C2I25_18825 d17c384cd0668d2b6050025a0f152058 259 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 57 245 3.3E-19 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain C2I25_18825 d17c384cd0668d2b6050025a0f152058 259 Gene3D G3DSA:3.40.50.1110 20 255 4.1E-29 T 14-10-2018 IPR036514 SGNH hydrolase superfamily C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 Gene3D G3DSA:1.20.1560.10 3 314 9.8E-32 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 Pfam PF00005 ABC transporter 355 500 2.7E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 SMART SM00382 364 547 6.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 SUPERFAMILY SSF52540 330 570 2.92E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 3 531 2.2E-200 T 14-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 Gene3D G3DSA:3.40.50.300 325 572 6.9E-77 T 14-10-2018 C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 SUPERFAMILY SSF90123 5 315 6.28E-43 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_01905 4dc36a13de3d9ae6091ed7fc4b0031b3 574 Pfam PF00664 ABC transporter transmembrane region 26 280 3.9E-11 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 Gene3D G3DSA:3.40.710.10 325 655 1.5E-79 T 14-10-2018 C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 Pfam PF00905 Penicillin binding protein transpeptidase domain 345 650 1.2E-61 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 SUPERFAMILY SSF56601 326 654 1.35E-76 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 Pfam PF03717 Penicillin-binding Protein dimerisation domain 144 311 3.6E-34 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 Gene3D G3DSA:3.30.1390.30 165 236 1.5E-51 T 14-10-2018 C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 Gene3D G3DSA:3.10.450.100 25 132 4.5E-33 T 14-10-2018 C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 Gene3D G3DSA:3.90.1310.10 146 321 1.5E-51 T 14-10-2018 C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 SUPERFAMILY SSF56519 139 325 5.89E-40 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 SUPERFAMILY SSF54427 27 135 1.61E-31 T 14-10-2018 IPR032710 NTF2-like domain superfamily C2I25_27210 226b8aaf292b0fa6a57f798bd59ec20a 655 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 25 136 3.4E-28 T 14-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 C2I25_15910 120ee44bd60c0c0202adab1d60d2460a 90 Pfam PF13055 Protein of unknown function (DUF3917) 18 88 5.0E-48 T 14-10-2018 IPR025027 Protein of unknown function DUF3917 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 27 907 0.0 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 Gene3D G3DSA:2.70.150.10 121 262 9.1E-29 T 14-10-2018 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 Pfam PF00690 Cation transporter/ATPase, N-terminus 39 102 3.4E-16 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 414 427 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 724 735 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 861 882 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 293 309 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 776 792 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 310 329 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 706 721 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 756 769 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 PRINTS PR01836 Magnesium-transporting ATPase signature 811 832 3.8E-82 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 Gene3D G3DSA:3.40.50.1000 555 698 1.1E-29 T 14-10-2018 IPR023214 HAD superfamily C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 Gene3D G3DSA:3.40.1110.10 391 554 1.9E-58 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 Gene3D G3DSA:1.20.1110.10 264 390 1.3E-11 T 14-10-2018 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 Pfam PF00702 haloacid dehalogenase-like hydrolase 376 662 4.4E-23 T 14-10-2018 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 SMART SM00831 34 107 2.7E-20 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 382 388 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 SUPERFAMILY SSF81653 162 280 1.44E-27 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 Pfam PF00122 E1-E2 ATPase 164 360 3.2E-45 T 14-10-2018 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 SUPERFAMILY SSF56784 541 690 6.75E-38 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 615 737 5.1E-29 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 280 401 5.4E-20 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 SUPERFAMILY SSF81660 348 552 4.36E-41 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_18705 8caac0aac6bff222d12c97a1a83a7755 908 SUPERFAMILY SSF81665 42 905 7.72E-103 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 Gene3D G3DSA:3.40.50.720 1 253 1.5E-83 T 14-10-2018 C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 9.7E-59 T 14-10-2018 C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.4E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 3.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 3.5E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23850 6133050fac31c3936c6c8f6cb1b7ef95 254 SUPERFAMILY SSF51735 5 253 1.92E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_17645 d4fba39a393fb8a815d050b6a8cb4d9f 185 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I25_17645 d4fba39a393fb8a815d050b6a8cb4d9f 185 Gene3D G3DSA:3.40.140.10 2 146 2.9E-46 T 14-10-2018 C2I25_17645 d4fba39a393fb8a815d050b6a8cb4d9f 185 SUPERFAMILY SSF53927 7 145 1.32E-40 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_17645 d4fba39a393fb8a815d050b6a8cb4d9f 185 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 151 8.1E-91 T 14-10-2018 IPR013404 Competence operon E, ComEB C2I25_17645 d4fba39a393fb8a815d050b6a8cb4d9f 185 PIRSF PIRSF006019 1 151 5.6E-58 T 14-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 C2I25_17645 d4fba39a393fb8a815d050b6a8cb4d9f 185 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 1.5E-28 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I25_02375 5283d82e0fb31cc7c173fe2f1946fb40 253 SUPERFAMILY SSF53213 1 253 4.05E-80 T 14-10-2018 C2I25_02375 5283d82e0fb31cc7c173fe2f1946fb40 253 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 4 244 1.1E-41 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 C2I25_02375 5283d82e0fb31cc7c173fe2f1946fb40 253 PIRSF PIRSF006157 1 253 8.7E-95 T 14-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 C2I25_02375 5283d82e0fb31cc7c173fe2f1946fb40 253 Gene3D G3DSA:3.40.830.10 1 253 8.5E-84 T 14-10-2018 C2I25_18625 144761fe64a9f1e5e828fe061dd08d38 234 Pfam PF04239 Protein of unknown function (DUF421) 98 211 1.0E-26 T 14-10-2018 IPR007353 Protein of unknown function DUF421 C2I25_18625 144761fe64a9f1e5e828fe061dd08d38 234 Gene3D G3DSA:3.30.240.20 179 234 4.9E-7 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_18625 144761fe64a9f1e5e828fe061dd08d38 234 Gene3D G3DSA:3.30.240.20 90 164 6.3E-19 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_18165 f02b25df6168532b20e74221ff6fbec1 560 SUPERFAMILY SSF52540 168 518 5.65E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18165 f02b25df6168532b20e74221ff6fbec1 560 SUPERFAMILY SSF52540 16 241 2.47E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18165 f02b25df6168532b20e74221ff6fbec1 560 Gene3D G3DSA:3.40.50.300 270 552 1.5E-52 T 14-10-2018 C2I25_18165 f02b25df6168532b20e74221ff6fbec1 560 SMART SM00487 56 235 8.5E-30 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I25_18165 f02b25df6168532b20e74221ff6fbec1 560 Gene3D G3DSA:3.40.50.10810 62 261 8.5E-42 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily C2I25_18165 f02b25df6168532b20e74221ff6fbec1 560 SMART SM00490 386 466 1.0E-20 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_18165 f02b25df6168532b20e74221ff6fbec1 560 Pfam PF00271 Helicase conserved C-terminal domain 363 466 2.8E-20 T 14-10-2018 IPR001650 Helicase, C-terminal C2I25_18165 f02b25df6168532b20e74221ff6fbec1 560 Pfam PF00176 SNF2 family N-terminal domain 79 333 2.3E-36 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 C2I25_14285 9b4ead449226a058577c1df55e421889 88 Pfam PF11256 Protein of unknown function (DUF3055) 7 85 3.0E-36 T 14-10-2018 IPR021415 Protein of unknown function DUF3055 C2I25_19595 5a038ea9977f6e5577a99ef6785d6e71 221 SUPERFAMILY SSF116726 135 220 2.62E-21 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_19595 5a038ea9977f6e5577a99ef6785d6e71 221 Gene3D G3DSA:3.30.70.1450 141 218 3.3E-28 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_19595 5a038ea9977f6e5577a99ef6785d6e71 221 Pfam PF02080 TrkA-C domain 153 219 2.3E-17 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I25_19595 5a038ea9977f6e5577a99ef6785d6e71 221 Gene3D G3DSA:3.40.50.720 2 140 1.1E-38 T 14-10-2018 C2I25_19595 5a038ea9977f6e5577a99ef6785d6e71 221 Pfam PF02254 TrkA-N domain 8 123 1.2E-29 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I25_19595 5a038ea9977f6e5577a99ef6785d6e71 221 SUPERFAMILY SSF51735 7 137 1.64E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_11515 973b83198b3d4cb3635a1ac8b87858d4 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 108 3.0E-33 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family C2I25_11515 973b83198b3d4cb3635a1ac8b87858d4 109 Gene3D G3DSA:3.30.1310.10 3 109 1.1E-40 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily C2I25_11515 973b83198b3d4cb3635a1ac8b87858d4 109 PIRSF PIRSF004555 5 109 1.2E-39 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family C2I25_11515 973b83198b3d4cb3635a1ac8b87858d4 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 7 101 23.631 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family C2I25_11515 973b83198b3d4cb3635a1ac8b87858d4 109 SUPERFAMILY SSF82607 13 106 3.27E-34 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily C2I25_11515 973b83198b3d4cb3635a1ac8b87858d4 109 Pfam PF02575 YbaB/EbfC DNA-binding family 13 103 4.0E-35 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family C2I25_03445 b0bee77bc536a02eabba0d8d79651619 484 Pfam PF01943 Polysaccharide biosynthesis protein 12 277 2.9E-21 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I25_12430 527c5ca178f5f0743c2b214121c92867 317 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 1 302 4.8E-100 T 14-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 C2I25_12430 527c5ca178f5f0743c2b214121c92867 317 Gene3D G3DSA:3.20.20.150 2 307 2.0E-95 T 14-10-2018 C2I25_12430 527c5ca178f5f0743c2b214121c92867 317 Pfam PF03851 UV-endonuclease UvdE 5 273 9.7E-122 T 14-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 C2I25_12430 527c5ca178f5f0743c2b214121c92867 317 Hamap MF_00606 UV DNA damage endonuclease [uvsE]. 12 303 41.592 T 14-10-2018 IPR023520 UV-endonuclease UvdE, bacterial GO:0004519|GO:0009411 C2I25_12430 527c5ca178f5f0743c2b214121c92867 317 SUPERFAMILY SSF51658 83 256 8.36E-17 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily C2I25_26440 6338d4aa8b4753bc4eaccbe53703bf35 192 Gene3D G3DSA:2.60.120.10 46 190 3.6E-35 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_26440 6338d4aa8b4753bc4eaccbe53703bf35 192 SUPERFAMILY SSF51182 8 189 4.21E-32 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_26440 6338d4aa8b4753bc4eaccbe53703bf35 192 Pfam PF05995 Cysteine dioxygenase type I 54 170 6.1E-6 T 14-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 C2I25_10570 ea2dc328a68f8380e958ec9c19b2f057 334 SUPERFAMILY SSF161098 98 295 4.25E-21 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10570 ea2dc328a68f8380e958ec9c19b2f057 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 312 2.0E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_10570 ea2dc328a68f8380e958ec9c19b2f057 334 Gene3D G3DSA:1.10.3720.10 93 313 2.9E-18 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10570 ea2dc328a68f8380e958ec9c19b2f057 334 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 81 4.4E-7 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I25_28270 77287df98cdaa914c5bb909db8e30d10 381 Pfam PF07690 Major Facilitator Superfamily 13 281 1.0E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_28270 77287df98cdaa914c5bb909db8e30d10 381 Gene3D G3DSA:1.20.1250.20 4 378 3.6E-60 T 14-10-2018 C2I25_28270 77287df98cdaa914c5bb909db8e30d10 381 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_28270 77287df98cdaa914c5bb909db8e30d10 381 SUPERFAMILY SSF103473 7 377 2.22E-64 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_02880 fd5964a94148fe8102db2059589dd8ad 191 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 163 1.6E-29 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_02880 fd5964a94148fe8102db2059589dd8ad 191 SMART SM00855 3 144 1.6E-7 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_02880 fd5964a94148fe8102db2059589dd8ad 191 Gene3D G3DSA:3.40.50.1240 1 183 1.6E-34 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_02880 fd5964a94148fe8102db2059589dd8ad 191 SUPERFAMILY SSF53254 1 175 2.63E-36 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 57.925 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 2.6E-68 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 SMART SM00382 147 410 7.9E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 Gene3D G3DSA:1.10.1140.10 351 468 1.2E-56 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 Gene3D G3DSA:2.40.10.170 2 79 5.5E-32 T 14-10-2018 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 Gene3D G3DSA:3.40.50.300 81 349 3.2E-116 T 14-10-2018 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 4.0E-26 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 SUPERFAMILY SSF52540 81 353 4.43E-90 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 1.1E-259 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 SUPERFAMILY SSF50615 1 78 3.92E-27 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 SUPERFAMILY SSF47917 351 466 7.59E-53 T 14-10-2018 C2I25_12655 b889063ff10c5da6c8bb30a772352a08 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I25_06425 95c2c4a1fbe4524ba978a3b4ad271127 146 Pfam PF00210 Ferritin-like domain 9 140 1.8E-25 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 C2I25_06425 95c2c4a1fbe4524ba978a3b4ad271127 146 Gene3D G3DSA:1.20.1260.10 1 146 6.6E-53 T 14-10-2018 IPR012347 Ferritin-like C2I25_06425 95c2c4a1fbe4524ba978a3b4ad271127 146 SUPERFAMILY SSF47240 6 140 4.26E-29 T 14-10-2018 IPR009078 Ferritin-like superfamily C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 PIRSF PIRSF000538 2 496 1.3E-183 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 SUPERFAMILY SSF53067 254 491 4.66E-86 T 14-10-2018 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 59.906 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 Gene3D G3DSA:3.30.420.40 253 496 1.4E-89 T 14-10-2018 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 Gene3D G3DSA:3.30.420.40 1 252 2.0E-115 T 14-10-2018 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 1.4E-92 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 1.5E-63 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 493 1.2E-228 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I25_06270 7abfa257b77ccbe8f6d1c75ce6159239 496 SUPERFAMILY SSF53067 3 254 3.97E-99 T 14-10-2018 C2I25_27475 6203c1c6dfd637316a5b9a75f2f68041 337 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 1 333 2.7E-91 T 14-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 C2I25_27475 6203c1c6dfd637316a5b9a75f2f68041 337 Gene3D G3DSA:3.75.10.10 1 337 7.1E-102 T 14-10-2018 C2I25_27475 6203c1c6dfd637316a5b9a75f2f68041 337 SUPERFAMILY SSF55909 1 333 1.36E-98 T 14-10-2018 C2I25_20045 e0754fb782bb03717f1f71b744881225 441 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 346 366 - T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I25_20045 e0754fb782bb03717f1f71b744881225 441 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 27 423 2.7E-135 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I25_20045 e0754fb782bb03717f1f71b744881225 441 Pfam PF00860 Permease family 27 400 1.9E-111 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I25_22355 7334e0b6ba33621f0691ff5b86d7f140 344 Gene3D G3DSA:1.10.3470.10 16 342 5.5E-91 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_22355 7334e0b6ba33621f0691ff5b86d7f140 344 SUPERFAMILY SSF81345 13 339 4.97E-83 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_22355 7334e0b6ba33621f0691ff5b86d7f140 344 Pfam PF01032 FecCD transport family 30 339 1.2E-89 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_24395 8f5dd89a74c8115e5205f07006abd292 263 SUPERFAMILY SSF142921 10 67 3.27E-9 T 14-10-2018 IPR036930 WGR domain superfamily C2I25_24395 8f5dd89a74c8115e5205f07006abd292 263 Gene3D G3DSA:2.20.140.10 2 70 1.9E-24 T 14-10-2018 IPR036930 WGR domain superfamily C2I25_24395 8f5dd89a74c8115e5205f07006abd292 263 SMART SM00773 1 72 4.1E-20 T 14-10-2018 IPR008893 WGR domain C2I25_24395 8f5dd89a74c8115e5205f07006abd292 263 Pfam PF14024 Protein of unknown function (DUF4240) 81 205 9.0E-40 T 14-10-2018 IPR025334 Domain of unknown function (DUF4240 C2I25_24395 8f5dd89a74c8115e5205f07006abd292 263 Pfam PF05406 WGR domain 7 67 1.7E-16 T 14-10-2018 IPR008893 WGR domain C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 Gene3D G3DSA:3.40.50.300 254 482 7.5E-48 T 14-10-2018 C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 SMART SM00382 275 468 0.0014 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 SMART SM00382 31 219 1.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 Gene3D G3DSA:3.40.50.300 2 231 4.0E-57 T 14-10-2018 C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 Pfam PF00005 ABC transporter 267 419 3.0E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 Pfam PF00005 ABC transporter 22 165 2.0E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 SUPERFAMILY SSF52540 264 477 2.33E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24690 203c897ecc47b0d5e1db92189227e746 493 SUPERFAMILY SSF52540 5 223 9.76E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18495 66799eb31e8ca769e4e738ba8d0e305e 555 PIRSF PIRSF014677 8 540 1.7E-135 T 14-10-2018 IPR011202 Uncharacterised conserved protein UCP014677 C2I25_18495 66799eb31e8ca769e4e738ba8d0e305e 555 Pfam PF13289 SIR2-like domain 140 246 1.4E-23 T 14-10-2018 IPR039444 SIR2-like domain C2I25_00130 40905857f66d0b08e4003e8c92d10ac4 345 Gene3D G3DSA:3.40.50.720 148 286 6.2E-113 T 14-10-2018 C2I25_00130 40905857f66d0b08e4003e8c92d10ac4 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 C2I25_00130 40905857f66d0b08e4003e8c92d10ac4 345 Gene3D G3DSA:3.90.180.10 27 334 6.2E-113 T 14-10-2018 C2I25_00130 40905857f66d0b08e4003e8c92d10ac4 345 SMART SM00829 9 335 9.3E-8 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_00130 40905857f66d0b08e4003e8c92d10ac4 345 Pfam PF00107 Zinc-binding dehydrogenase 174 297 1.2E-23 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_00130 40905857f66d0b08e4003e8c92d10ac4 345 SUPERFAMILY SSF51735 137 305 8.68E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_00130 40905857f66d0b08e4003e8c92d10ac4 345 SUPERFAMILY SSF50129 1 179 7.61E-48 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_00130 40905857f66d0b08e4003e8c92d10ac4 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 133 2.0E-29 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_03685 b28c9fe46bcbdb3f7840b4d9814f94e5 127 SUPERFAMILY SSF50692 1 120 7.04E-52 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily C2I25_03685 b28c9fe46bcbdb3f7840b4d9814f94e5 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 90 6.0E-44 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I25_03685 b28c9fe46bcbdb3f7840b4d9814f94e5 127 Pfam PF02261 Aspartate decarboxylase 1 114 2.9E-54 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I25_03685 b28c9fe46bcbdb3f7840b4d9814f94e5 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 3.4E-57 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I25_03685 b28c9fe46bcbdb3f7840b4d9814f94e5 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 74.571 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I25_03685 b28c9fe46bcbdb3f7840b4d9814f94e5 127 PIRSF PIRSF006246 1 126 1.7E-55 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I25_03685 b28c9fe46bcbdb3f7840b4d9814f94e5 127 Gene3D G3DSA:2.40.40.20 1 123 6.7E-55 T 14-10-2018 C2I25_01385 53c02f9e3f7efe9315384e30117eb401 207 Pfam PF13460 NAD(P)H-binding 7 193 1.0E-37 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_01385 53c02f9e3f7efe9315384e30117eb401 207 SUPERFAMILY SSF51735 1 204 3.34E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_01385 53c02f9e3f7efe9315384e30117eb401 207 Gene3D G3DSA:3.40.50.720 1 207 1.1E-39 T 14-10-2018 C2I25_08600 86031966da2b00a665d9ff1628cf5eef 235 PIRSF PIRSF006171 1 229 1.2E-83 T 14-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 C2I25_08600 86031966da2b00a665d9ff1628cf5eef 235 SUPERFAMILY SSF52172 1 133 6.26E-36 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_08600 86031966da2b00a665d9ff1628cf5eef 235 SMART SM00448 2 115 6.3E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_08600 86031966da2b00a665d9ff1628cf5eef 235 Gene3D G3DSA:3.40.50.2300 1 138 1.7E-33 T 14-10-2018 C2I25_08600 86031966da2b00a665d9ff1628cf5eef 235 Pfam PF00072 Response regulator receiver domain 4 115 6.9E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_05965 92611a43979d1b51956ee703e860c2b4 244 SUPERFAMILY SSF56281 1 242 1.24E-56 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_05965 92611a43979d1b51956ee703e860c2b4 244 Gene3D G3DSA:3.60.15.10 1 244 1.7E-102 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_05965 92611a43979d1b51956ee703e860c2b4 244 SMART SM00849 18 211 2.0E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_05965 92611a43979d1b51956ee703e860c2b4 244 Pfam PF12706 Beta-lactamase superfamily domain 30 211 1.2E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_06030 a1307d240be555cc975af1afad1c1cdb 788 Gene3D G3DSA:3.60.10.10 491 783 2.5E-41 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_06030 a1307d240be555cc975af1afad1c1cdb 788 SUPERFAMILY SSF56219 486 786 3.53E-32 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_06030 a1307d240be555cc975af1afad1c1cdb 788 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 156 222 4.8E-18 T 14-10-2018 C2I25_06030 a1307d240be555cc975af1afad1c1cdb 788 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 494 775 7.5E-9 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase C2I25_22940 abb62ba87c592002a7b0efda561d3777 355 SUPERFAMILY SSF51004 19 354 3.14E-50 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily C2I25_22940 abb62ba87c592002a7b0efda561d3777 355 Pfam PF10282 Lactonase, 7-bladed beta-propeller 12 352 6.0E-133 T 14-10-2018 IPR019405 Lactonase, 7-bladed beta propeller C2I25_22940 abb62ba87c592002a7b0efda561d3777 355 Gene3D G3DSA:2.130.10.10 10 355 4.6E-127 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 Pfam PF00106 short chain dehydrogenase 7 200 3.8E-68 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 Gene3D G3DSA:3.40.50.720 1 246 1.0E-87 T 14-10-2018 C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 6.3E-5 T 14-10-2018 C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 8.8E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 7 247 7.8E-94 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 SUPERFAMILY SSF51735 5 247 7.52E-87 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.0E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.0E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_04840 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.0E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_25095 523d790e2bae76852833f3e5c939c45f 400 SUPERFAMILY SSF103473 3 391 1.28E-46 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_25095 523d790e2bae76852833f3e5c939c45f 400 Pfam PF05977 Transmembrane secretion effector 9 311 9.2E-15 T 14-10-2018 IPR010290 Transmembrane secretion effector C2I25_25095 523d790e2bae76852833f3e5c939c45f 400 Gene3D G3DSA:1.20.1250.20 2 386 9.0E-38 T 14-10-2018 C2I25_12605 9dee88e226f49d03980f1c8ac34b68ff 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 2.4E-75 T 14-10-2018 C2I25_12605 9dee88e226f49d03980f1c8ac34b68ff 209 Gene3D G3DSA:3.40.50.2020 1 209 5.1E-83 T 14-10-2018 C2I25_12605 9dee88e226f49d03980f1c8ac34b68ff 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 1.3E-92 T 14-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 C2I25_12605 9dee88e226f49d03980f1c8ac34b68ff 209 SUPERFAMILY SSF53271 4 207 9.96E-73 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_12605 9dee88e226f49d03980f1c8ac34b68ff 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.969 T 14-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 C2I25_08015 712c6d3fcf45066d4669312f9af63678 66 Gene3D G3DSA:1.10.260.40 1 65 1.8E-25 T 14-10-2018 C2I25_08015 712c6d3fcf45066d4669312f9af63678 66 SUPERFAMILY SSF47413 5 64 4.29E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_08015 712c6d3fcf45066d4669312f9af63678 66 Pfam PF01381 Helix-turn-helix 6 56 2.2E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_08015 712c6d3fcf45066d4669312f9af63678 66 SMART SM00530 5 60 1.1E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_27565 cd0eca2be9f320c6e431c510cb09038c 236 Gene3D G3DSA:3.40.50.150 21 234 1.0E-38 T 14-10-2018 C2I25_27565 cd0eca2be9f320c6e431c510cb09038c 236 SUPERFAMILY SSF53335 25 212 3.5E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_27565 cd0eca2be9f320c6e431c510cb09038c 236 Pfam PF13649 Methyltransferase domain 63 156 5.2E-18 T 14-10-2018 C2I25_22710 83becc9118c481c4b45a9d0a782cde09 108 Gene3D G3DSA:1.10.10.10 1 108 5.6E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22710 83becc9118c481c4b45a9d0a782cde09 108 SUPERFAMILY SSF46785 2 102 6.0E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22710 83becc9118c481c4b45a9d0a782cde09 108 Pfam PF01638 HxlR-like helix-turn-helix 14 102 5.3E-37 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_19125 d3dda0554a8a80cc6a83065a307afc29 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 333 1.2E-155 T 14-10-2018 IPR010894 Stage V sporulation AD C2I25_19125 d3dda0554a8a80cc6a83065a307afc29 338 PIRSF PIRSF011570 1 336 5.7E-164 T 14-10-2018 IPR010894 Stage V sporulation AD C2I25_19125 d3dda0554a8a80cc6a83065a307afc29 338 Gene3D G3DSA:3.40.47.40 1 338 9.4E-155 T 14-10-2018 IPR038369 Stage V sporulation AD superfamily C2I25_19125 d3dda0554a8a80cc6a83065a307afc29 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 333 1.6E-161 T 14-10-2018 IPR010894 Stage V sporulation AD C2I25_19125 d3dda0554a8a80cc6a83065a307afc29 338 SUPERFAMILY SSF53901 57 310 2.54E-15 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_17915 7565fef79d3e11c84f7d5707046c8b34 425 Gene3D G3DSA:1.20.1250.20 10 341 2.8E-26 T 14-10-2018 C2I25_17915 7565fef79d3e11c84f7d5707046c8b34 425 Pfam PF07690 Major Facilitator Superfamily 20 337 7.6E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_17915 7565fef79d3e11c84f7d5707046c8b34 425 SUPERFAMILY SSF103473 13 342 5.1E-29 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_15865 7ce6c2777e3fb661d43674170312f7e0 109 Pfam PF11009 Protein of unknown function (DUF2847) 6 104 1.9E-37 T 14-10-2018 IPR022551 Protein of unknown function DUF2847 C2I25_15865 7ce6c2777e3fb661d43674170312f7e0 109 Gene3D G3DSA:3.40.30.10 1 108 7.0E-40 T 14-10-2018 C2I25_15865 7ce6c2777e3fb661d43674170312f7e0 109 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 6 105 2.6E-39 T 14-10-2018 IPR022551 Protein of unknown function DUF2847 C2I25_15865 7ce6c2777e3fb661d43674170312f7e0 109 SUPERFAMILY SSF52833 2 105 6.78E-10 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_09940 ac4cc4d397f637c3ada25c4f8cfe077a 161 PIRSF PIRSF001338 1 161 2.3E-68 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 C2I25_09940 ac4cc4d397f637c3ada25c4f8cfe077a 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 157 2.1E-67 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 C2I25_09940 ac4cc4d397f637c3ada25c4f8cfe077a 161 SMART SM01001 3 154 3.6E-105 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 C2I25_09940 ac4cc4d397f637c3ada25c4f8cfe077a 161 Pfam PF00731 AIR carboxylase 5 150 2.9E-66 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 C2I25_09940 ac4cc4d397f637c3ada25c4f8cfe077a 161 Gene3D G3DSA:3.40.50.7700 1 161 5.0E-76 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 C2I25_09940 ac4cc4d397f637c3ada25c4f8cfe077a 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.345 T 14-10-2018 IPR033747 Class I PurE C2I25_09940 ac4cc4d397f637c3ada25c4f8cfe077a 161 SUPERFAMILY SSF52255 4 158 2.49E-68 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 570 1.1E-211 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 SUPERFAMILY SSF46600 182 235 1.31E-13 T 14-10-2018 IPR036876 UVR domain superfamily C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 SMART SM00465 15 95 8.3E-21 T 14-10-2018 IPR000305 GIY-YIG endonuclease C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 Pfam PF01541 GIY-YIG catalytic domain 16 90 5.7E-10 T 14-10-2018 IPR000305 GIY-YIG endonuclease C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 28.405 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 Pfam PF02151 UvrB/uvrC motif 196 229 1.0E-8 T 14-10-2018 IPR001943 UVR domain GO:0005515 C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 372 523 1.1E-54 T 14-10-2018 IPR001162 UvrC family homology region C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 SUPERFAMILY SSF82771 14 97 2.62E-22 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 Gene3D G3DSA:1.10.150.20 527 589 6.5E-21 T 14-10-2018 C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 Gene3D G3DSA:3.40.1440.10 1 99 3.1E-37 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 Gene3D G3DSA:3.30.420.340 365 523 3.8E-62 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily C2I25_16725 0a9d9f44d98c446872d7ad8f05994245 594 SUPERFAMILY SSF47781 500 591 1.05E-21 T 14-10-2018 IPR010994 RuvA domain 2-like C2I25_27795 98a0d864c6d0e599e17b9228ae3341df 207 SUPERFAMILY SSF49842 110 189 2.68E-5 T 14-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I25_27795 98a0d864c6d0e599e17b9228ae3341df 207 Pfam PF01391 Collagen triple helix repeat (20 copies) 30 69 9.6E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_22280 322974d451d9e526cb862d37e6b2e2de 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 8.7E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_22280 322974d451d9e526cb862d37e6b2e2de 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 102 127 8.7E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_22280 322974d451d9e526cb862d37e6b2e2de 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 8.7E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_22280 322974d451d9e526cb862d37e6b2e2de 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 8.7E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_22280 322974d451d9e526cb862d37e6b2e2de 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 256 263 8.7E-12 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_22280 322974d451d9e526cb862d37e6b2e2de 263 Gene3D G3DSA:3.30.2140.20 1 263 4.5E-102 T 14-10-2018 C2I25_22280 322974d451d9e526cb862d37e6b2e2de 263 Pfam PF00797 N-acetyltransferase 23 263 7.4E-46 T 14-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I25_22280 322974d451d9e526cb862d37e6b2e2de 263 SUPERFAMILY SSF54001 2 263 1.08E-68 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_22970 131b05b6947bba60aed5cc6bdaca723d 307 SUPERFAMILY SSF51735 1 301 5.16E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22970 131b05b6947bba60aed5cc6bdaca723d 307 Gene3D G3DSA:3.40.50.720 5 281 9.9E-57 T 14-10-2018 C2I25_22970 131b05b6947bba60aed5cc6bdaca723d 307 Gene3D G3DSA:3.90.25.10 172 288 9.9E-57 T 14-10-2018 C2I25_22970 131b05b6947bba60aed5cc6bdaca723d 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 226 2.1E-43 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_18940 7461a36a17cdcfe36b549747cf8cdde2 332 Pfam PF12146 Serine aminopeptidase, S33 48 161 2.3E-15 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 C2I25_18940 7461a36a17cdcfe36b549747cf8cdde2 332 Gene3D G3DSA:3.40.50.1820 24 324 7.3E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_18940 7461a36a17cdcfe36b549747cf8cdde2 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 125 139 7.3E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 C2I25_18940 7461a36a17cdcfe36b549747cf8cdde2 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 49 57 7.3E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 C2I25_18940 7461a36a17cdcfe36b549747cf8cdde2 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 77 88 7.3E-9 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 C2I25_18940 7461a36a17cdcfe36b549747cf8cdde2 332 SUPERFAMILY SSF53474 39 321 1.5E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_18105 c19d4c1793d0aeef6ba889586095773d 151 PIRSF PIRSF021292 1 144 6.9E-55 T 14-10-2018 IPR016785 ComG operon protein 4 GO:0030420 C2I25_18105 c19d4c1793d0aeef6ba889586095773d 151 SUPERFAMILY SSF54523 6 128 5.96E-10 T 14-10-2018 C2I25_18105 c19d4c1793d0aeef6ba889586095773d 151 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 1.5E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I25_18105 c19d4c1793d0aeef6ba889586095773d 151 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 26 4.1E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I25_14555 cd94c3acd223800c3ab889b4b465e119 197 Gene3D G3DSA:1.10.1760.20 1 187 6.3E-43 T 14-10-2018 C2I25_14555 cd94c3acd223800c3ab889b4b465e119 197 Pfam PF02632 BioY family 36 180 4.6E-29 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I25_14555 cd94c3acd223800c3ab889b4b465e119 197 PIRSF PIRSF016661 1 190 2.1E-41 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I25_12165 2c2aeffa00a15da72b51ae34df96a042 269 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 61 246 2.3E-23 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain C2I25_12165 2c2aeffa00a15da72b51ae34df96a042 269 SUPERFAMILY SSF52266 55 258 3.66E-38 T 14-10-2018 C2I25_12165 2c2aeffa00a15da72b51ae34df96a042 269 Gene3D G3DSA:3.40.50.1110 26 255 4.6E-36 T 14-10-2018 IPR036514 SGNH hydrolase superfamily C2I25_10785 b6357799c97d4653f44cdb7caf33411f 355 Gene3D G3DSA:3.40.50.300 98 324 1.7E-66 T 14-10-2018 C2I25_10785 b6357799c97d4653f44cdb7caf33411f 355 SUPERFAMILY SSF117916 1 69 5.23E-7 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I25_10785 b6357799c97d4653f44cdb7caf33411f 355 Pfam PF01883 Iron-sulfur cluster assembly protein 4 57 2.4E-5 T 14-10-2018 IPR002744 MIP18 family-like C2I25_10785 b6357799c97d4653f44cdb7caf33411f 355 ProSitePatterns PS01215 Mrp family signature. 212 228 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 C2I25_10785 b6357799c97d4653f44cdb7caf33411f 355 Hamap MF_02040 Iron-sulfur cluster carrier protein. 99 347 33.87 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein C2I25_10785 b6357799c97d4653f44cdb7caf33411f 355 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 109 346 3.2E-84 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 C2I25_10785 b6357799c97d4653f44cdb7caf33411f 355 SUPERFAMILY SSF52540 101 315 5.75E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08705 393dbcf8662dfdeaa28a13bb4181197d 522 Gene3D G3DSA:3.30.479.30 77 193 1.4E-36 T 14-10-2018 C2I25_08705 393dbcf8662dfdeaa28a13bb4181197d 522 Pfam PF15975 Flotillin 378 471 1.5E-14 T 14-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 C2I25_08705 393dbcf8662dfdeaa28a13bb4181197d 522 SMART SM00244 34 203 0.0021 T 14-10-2018 IPR001107 Band 7 domain C2I25_08705 393dbcf8662dfdeaa28a13bb4181197d 522 Pfam PF01145 SPFH domain / Band 7 family 28 220 4.8E-23 T 14-10-2018 IPR001107 Band 7 domain C2I25_08705 393dbcf8662dfdeaa28a13bb4181197d 522 SUPERFAMILY SSF117892 68 210 1.24E-33 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily C2I25_18095 7952a371153a883a73c9f60657ba467c 345 Pfam PF00482 Type II secretion system (T2SS), protein F 215 337 4.8E-18 T 14-10-2018 IPR018076 Type II secretion system F domain C2I25_18095 7952a371153a883a73c9f60657ba467c 345 Pfam PF00482 Type II secretion system (T2SS), protein F 17 136 3.5E-15 T 14-10-2018 IPR018076 Type II secretion system F domain C2I25_18095 7952a371153a883a73c9f60657ba467c 345 Gene3D G3DSA:1.20.81.30 198 310 5.7E-12 T 14-10-2018 C2I25_18095 7952a371153a883a73c9f60657ba467c 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 310 324 5.7E-6 T 14-10-2018 IPR003004 GspF/PilC family C2I25_18095 7952a371153a883a73c9f60657ba467c 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 326 345 5.7E-6 T 14-10-2018 IPR003004 GspF/PilC family C2I25_18095 7952a371153a883a73c9f60657ba467c 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 108 136 5.7E-6 T 14-10-2018 IPR003004 GspF/PilC family C2I25_18095 7952a371153a883a73c9f60657ba467c 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 12 24 5.7E-6 T 14-10-2018 IPR003004 GspF/PilC family C2I25_18095 7952a371153a883a73c9f60657ba467c 345 Gene3D G3DSA:1.20.81.30 3 116 1.4E-11 T 14-10-2018 C2I25_10840 01af3b4a61a994c42ec31f1cbad3bf40 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site C2I25_10840 01af3b4a61a994c42ec31f1cbad3bf40 129 PIRSF PIRSF002131 1 129 4.2E-54 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 C2I25_10840 01af3b4a61a994c42ec31f1cbad3bf40 129 SUPERFAMILY SSF53137 14 129 3.86E-50 T 14-10-2018 C2I25_10840 01af3b4a61a994c42ec31f1cbad3bf40 129 Pfam PF00411 Ribosomal protein S11 19 128 1.4E-51 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 C2I25_10840 01af3b4a61a994c42ec31f1cbad3bf40 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 3.0E-59 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10840 01af3b4a61a994c42ec31f1cbad3bf40 129 Gene3D G3DSA:3.30.420.80 1 129 1.8E-55 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_10840 01af3b4a61a994c42ec31f1cbad3bf40 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.407 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 C2I25_20910 141da57a510a22346ffa70d8569a65c7 464 TIGRFAM TIGR01773 GABAperm: GABA permease 4 447 1.3E-206 T 14-10-2018 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 C2I25_20910 141da57a510a22346ffa70d8569a65c7 464 Gene3D G3DSA:1.20.1740.10 3 461 4.5E-73 T 14-10-2018 C2I25_20910 141da57a510a22346ffa70d8569a65c7 464 Pfam PF00324 Amino acid permease 13 450 6.6E-119 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I25_20910 141da57a510a22346ffa70d8569a65c7 464 PIRSF PIRSF006060 2 463 4.2E-80 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_20910 141da57a510a22346ffa70d8569a65c7 464 ProSitePatterns PS00218 Amino acid permeases signature. 38 68 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I25_27925 9c4626df816cb8ddfa16929d29162bc9 183 SUPERFAMILY SSF55729 1 174 2.8E-45 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27925 9c4626df816cb8ddfa16929d29162bc9 183 Gene3D G3DSA:3.40.630.30 5 178 4.9E-43 T 14-10-2018 C2I25_27925 9c4626df816cb8ddfa16929d29162bc9 183 Pfam PF13302 Acetyltransferase (GNAT) domain 10 150 2.3E-26 T 14-10-2018 IPR000182 GNAT domain C2I25_26555 8857224dfd7d980d4dde93d96f9a2730 1282 SUPERFAMILY SSF48371 702 1127 1.58E-5 T 14-10-2018 IPR016024 Armadillo-type fold C2I25_26555 8857224dfd7d980d4dde93d96f9a2730 1282 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 285 643 8.4E-59 T 14-10-2018 IPR010090 Phage tail tape measure protein C2I25_26555 8857224dfd7d980d4dde93d96f9a2730 1282 Pfam PF10145 Phage-related minor tail protein 337 536 2.9E-34 T 14-10-2018 IPR010090 Phage tail tape measure protein C2I25_26555 8857224dfd7d980d4dde93d96f9a2730 1282 Gene3D G3DSA:1.10.287.700 979 1136 1.5E-5 T 14-10-2018 C2I25_26555 8857224dfd7d980d4dde93d96f9a2730 1282 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 6 595 0.006 T 14-10-2018 C2I25_23975 2cff5674ff5b88d5756bc99df77c0285 121 Gene3D G3DSA:2.40.50.480 27 117 3.6E-14 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_23975 2cff5674ff5b88d5756bc99df77c0285 121 SUPERFAMILY SSF159121 27 117 2.88E-17 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_23975 2cff5674ff5b88d5756bc99df77c0285 121 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 15 114 2.9E-8 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_23975 2cff5674ff5b88d5756bc99df77c0285 121 Pfam PF06486 Protein of unknown function (DUF1093) 34 106 4.6E-8 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 PRINTS PR00471 Acetate kinase family signature 180 201 3.9E-17 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 PRINTS PR00471 Acetate kinase family signature 298 314 3.9E-17 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 PRINTS PR00471 Acetate kinase family signature 6 17 3.9E-17 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 PRINTS PR00471 Acetate kinase family signature 275 288 3.9E-17 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 PIRSF PIRSF036458 2 357 2.6E-180 T 14-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 5 354 1.8E-174 T 14-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 SUPERFAMILY SSF53067 4 173 9.72E-75 T 14-10-2018 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 SUPERFAMILY SSF53067 118 348 1.47E-56 T 14-10-2018 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 Gene3D G3DSA:3.30.420.40 138 333 1.6E-161 T 14-10-2018 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 180 197 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 Gene3D G3DSA:3.30.420.40 5 356 1.6E-161 T 14-10-2018 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 Pfam PF00871 Acetokinase family 6 362 2.4E-75 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 Hamap MF_00542 Probable butyrate kinase [buk]. 1 367 174.503 T 14-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 C2I25_18590 d1e25850d3d5af9c25064e9054e1bf85 367 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 SUPERFAMILY SSF53850 88 281 7.76E-36 T 14-10-2018 C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 SUPERFAMILY SSF46785 2 110 5.99E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 Pfam PF03466 LysR substrate binding domain 88 280 1.8E-40 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 Gene3D G3DSA:3.40.190.290 90 283 8.6E-39 T 14-10-2018 C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 Gene3D G3DSA:1.10.10.10 1 89 7.8E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.2E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_22225 c9e5d1a6047f814c94d08806f3a6e948 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_01480 0660e320921e1143047fa05ab7455f3f 150 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 68 148 2.4E-31 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 C2I25_01480 0660e320921e1143047fa05ab7455f3f 150 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 147 40.146 T 14-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 C2I25_01480 0660e320921e1143047fa05ab7455f3f 150 Gene3D G3DSA:1.10.10.10 66 149 2.9E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01480 0660e320921e1143047fa05ab7455f3f 150 SUPERFAMILY SSF46767 66 148 6.8E-31 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 C2I25_01480 0660e320921e1143047fa05ab7455f3f 150 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 67 146 8.4E-34 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 C2I25_01480 0660e320921e1143047fa05ab7455f3f 150 Gene3D G3DSA:3.30.160.70 1 62 2.2E-12 T 14-10-2018 C2I25_01480 0660e320921e1143047fa05ab7455f3f 150 SUPERFAMILY SSF53155 1 71 3.14E-17 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 C2I25_01480 0660e320921e1143047fa05ab7455f3f 150 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 117 123 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 C2I25_06435 cf7e1c737dd596b2339a406a7f14b612 160 Pfam PF13581 Histidine kinase-like ATPase domain 12 140 7.8E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_06435 cf7e1c737dd596b2339a406a7f14b612 160 Gene3D G3DSA:3.30.565.10 5 150 2.2E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_06435 cf7e1c737dd596b2339a406a7f14b612 160 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 156 40.601 T 14-10-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 C2I25_06435 cf7e1c737dd596b2339a406a7f14b612 160 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 2 156 1.2E-70 T 14-10-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 C2I25_06435 cf7e1c737dd596b2339a406a7f14b612 160 SUPERFAMILY SSF55874 31 135 2.36E-14 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_02510 e0178a1e43a4742f73839b57c0884975 327 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 324 63.535 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I25_02510 e0178a1e43a4742f73839b57c0884975 327 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 324 1.5E-109 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I25_02510 e0178a1e43a4742f73839b57c0884975 327 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 186 1.1E-29 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I25_02510 e0178a1e43a4742f73839b57c0884975 327 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 324 2.0E-29 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I25_02510 e0178a1e43a4742f73839b57c0884975 327 Gene3D G3DSA:3.40.47.10 2 326 9.6E-114 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_02510 e0178a1e43a4742f73839b57c0884975 327 SUPERFAMILY SSF53901 3 324 1.98E-59 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 SUPERFAMILY SSF53633 4 311 5.5E-89 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 Pfam PF00696 Amino acid kinase family 5 293 1.5E-33 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 PRINTS PR01469 Bacterial carbamate kinase signature 159 178 2.6E-65 T 14-10-2018 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 2.6E-65 T 14-10-2018 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 PRINTS PR01469 Bacterial carbamate kinase signature 110 129 2.6E-65 T 14-10-2018 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 PRINTS PR01469 Bacterial carbamate kinase signature 267 282 2.6E-65 T 14-10-2018 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 2.6E-65 T 14-10-2018 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 PRINTS PR01469 Bacterial carbamate kinase signature 182 200 2.6E-65 T 14-10-2018 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 PRINTS PR01469 Bacterial carbamate kinase signature 212 227 2.6E-65 T 14-10-2018 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 PIRSF PIRSF000723 2 313 4.4E-127 T 14-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 Gene3D G3DSA:3.40.1160.10 2 313 3.6E-127 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I25_09475 d1def572650a85bbf757e37a125ef3ad 320 TIGRFAM TIGR00746 arcC: carbamate kinase 4 313 1.3E-135 T 14-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 C2I25_16685 f6d920cc59e0f5422453909ac4bfb45d 324 Pfam PF01497 Periplasmic binding protein 55 298 1.4E-30 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_16685 f6d920cc59e0f5422453909ac4bfb45d 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 301 314 3.1E-6 T 14-10-2018 C2I25_16685 f6d920cc59e0f5422453909ac4bfb45d 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 104 119 3.1E-6 T 14-10-2018 C2I25_16685 f6d920cc59e0f5422453909ac4bfb45d 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 72 90 3.1E-6 T 14-10-2018 C2I25_16685 f6d920cc59e0f5422453909ac4bfb45d 324 Gene3D G3DSA:3.40.50.1980 144 324 9.5E-37 T 14-10-2018 C2I25_16685 f6d920cc59e0f5422453909ac4bfb45d 324 Gene3D G3DSA:3.40.50.1980 30 140 1.4E-29 T 14-10-2018 C2I25_16685 f6d920cc59e0f5422453909ac4bfb45d 324 SUPERFAMILY SSF53807 37 314 1.61E-55 T 14-10-2018 C2I25_18215 062d18b5a9fe79107b6f574ac6c5151d 210 Pfam PF13346 ABC-2 family transporter protein 3 206 2.1E-35 T 14-10-2018 IPR025699 ABC-2 membrane transporter-like C2I25_18645 92d22842194b76b0f79f9b8d422dd557 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 256 1.7E-58 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_18645 92d22842194b76b0f79f9b8d422dd557 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site C2I25_18645 92d22842194b76b0f79f9b8d422dd557 259 Gene3D G3DSA:3.40.190.10 37 256 2.0E-64 T 14-10-2018 C2I25_18645 92d22842194b76b0f79f9b8d422dd557 259 SMART SM00062 35 258 1.4E-68 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_18645 92d22842194b76b0f79f9b8d422dd557 259 SMART SM00079 35 257 5.9E-5 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 C2I25_18645 92d22842194b76b0f79f9b8d422dd557 259 Gene3D G3DSA:3.40.190.10 123 215 2.0E-64 T 14-10-2018 C2I25_18645 92d22842194b76b0f79f9b8d422dd557 259 SUPERFAMILY SSF53850 1 257 3.11E-65 T 14-10-2018 C2I25_02080 03edcd53aa32b7f9463ac9cfb11f91ec 336 Pfam PF00487 Fatty acid desaturase 65 299 1.9E-39 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 Gene3D G3DSA:1.20.200.10 128 467 1.9E-127 T 14-10-2018 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 Gene3D G3DSA:1.10.40.30 371 449 1.9E-127 T 14-10-2018 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 5.5E-18 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 5.5E-18 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 5.5E-18 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 5.5E-18 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 SUPERFAMILY SSF48557 37 470 2.98E-93 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 TIGRFAM TIGR00838 argH: argininosuccinate lyase 33 472 5.8E-98 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 Pfam PF00206 Lyase 98 308 5.5E-42 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 Pfam PF14698 Argininosuccinate lyase C-terminal 375 447 4.0E-13 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 1.9E-27 T 14-10-2018 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 1.9E-27 T 14-10-2018 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 1.9E-27 T 14-10-2018 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 1.9E-27 T 14-10-2018 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 1.9E-27 T 14-10-2018 C2I25_21835 8b24466d2c17a3ae570e4fbc52bc3ee7 503 Gene3D G3DSA:1.10.275.10 43 238 1.9E-127 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I25_14340 05963b4d71252e758d575bbafdae2da0 163 SUPERFAMILY SSF101307 7 158 3.14E-58 T 14-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 C2I25_14340 05963b4d71252e758d575bbafdae2da0 163 Gene3D G3DSA:1.10.3760.10 1 163 2.4E-75 T 14-10-2018 C2I25_14340 05963b4d71252e758d575bbafdae2da0 163 PIRSF PIRSF019587 2 163 2.6E-77 T 14-10-2018 IPR026038 Putative phosphatidylglycerophosphatase C2I25_14340 05963b4d71252e758d575bbafdae2da0 163 Pfam PF04608 Phosphatidylglycerophosphatase A 13 156 3.7E-21 T 14-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 C2I25_17655 4484840451979ce20427cfca9f863e42 44 Pfam PF14141 YqzM-like protein 2 43 1.7E-25 T 14-10-2018 IPR025416 YqzM-like protein C2I25_05650 d69dd8ab664dfc145b06f78426a5696c 121 Hamap MF_01536 UPF0344 protein . 1 121 16.788 T 14-10-2018 IPR010899 Protein of unknown function UPF0344 C2I25_05650 d69dd8ab664dfc145b06f78426a5696c 121 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 121 1.0E-60 T 14-10-2018 IPR010899 Protein of unknown function UPF0344 C2I25_05650 d69dd8ab664dfc145b06f78426a5696c 121 Pfam PF07457 Protein of unknown function (DUF1516) 2 111 3.2E-33 T 14-10-2018 IPR010899 Protein of unknown function UPF0344 C2I25_17340 a2aaa6728f2e0871e8cec4e722fd837b 88 Hamap MF_01507 UPF0297 protein . 1 85 28.156 T 14-10-2018 IPR009309 Uncharacterised protein family UPF0297 C2I25_17340 a2aaa6728f2e0871e8cec4e722fd837b 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 2.1E-37 T 14-10-2018 IPR009309 Uncharacterised protein family UPF0297 C2I25_17340 a2aaa6728f2e0871e8cec4e722fd837b 88 PIRSF PIRSF037258 1 88 6.4E-45 T 14-10-2018 IPR009309 Uncharacterised protein family UPF0297 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 618 38.658 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 Gene3D G3DSA:1.20.58.760 407 607 5.1E-74 T 14-10-2018 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 110 602 3.3E-246 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 SUPERFAMILY SSF140990 412 604 7.32E-72 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 Pfam PF06480 FtsH Extracellular 9 104 2.5E-12 T 14-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 ProSitePatterns PS00674 AAA-protein family signature. 301 319 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 Gene3D G3DSA:1.10.8.60 332 406 4.2E-30 T 14-10-2018 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 Pfam PF01434 Peptidase family M41 392 601 8.0E-87 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 330 3.5E-46 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 Gene3D G3DSA:3.40.50.300 148 331 1.3E-71 T 14-10-2018 C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 SMART SM00382 194 333 3.6E-26 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_11275 7564841f6b16752efd38a4e9b5dee0ca 633 SUPERFAMILY SSF52540 154 402 8.52E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21700 fd44051c784a3d47524d516a7b26ff08 511 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 38 491 9.7E-172 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_21700 fd44051c784a3d47524d516a7b26ff08 511 PIRSF PIRSF005690 24 507 1.3E-187 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_23285 5b1ec23d380d63315eb87f62228edd24 233 Gene3D G3DSA:1.10.1760.20 56 217 4.5E-21 T 14-10-2018 C2I25_23285 5b1ec23d380d63315eb87f62228edd24 233 PIRSF PIRSF037395 1 233 5.0E-82 T 14-10-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 C2I25_23285 5b1ec23d380d63315eb87f62228edd24 233 Pfam PF07155 ECF-type riboflavin transporter, S component 58 200 7.0E-10 T 14-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 C2I25_26325 fbc96bce15abfcad62fed4aee622ae65 168 Pfam PF04229 GrpB protein 5 163 4.7E-45 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase C2I25_26325 fbc96bce15abfcad62fed4aee622ae65 168 Gene3D G3DSA:3.30.460.10 1 167 9.9E-51 T 14-10-2018 C2I25_26325 fbc96bce15abfcad62fed4aee622ae65 168 SUPERFAMILY SSF81301 7 166 3.11E-47 T 14-10-2018 C2I25_15060 c7a23d090eae3abfaabb04af36fb12a6 199 Pfam PF09335 SNARE associated Golgi protein 31 155 8.1E-24 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_11540 7d129e77e5dda0d699b3ec158e4888d9 179 Gene3D G3DSA:3.40.50.850 1 177 9.6E-41 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_11540 7d129e77e5dda0d699b3ec158e4888d9 179 SUPERFAMILY SSF52499 2 176 1.83E-44 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_11540 7d129e77e5dda0d699b3ec158e4888d9 179 Pfam PF00857 Isochorismatase family 4 165 6.9E-29 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_02415 80b754234266a6b7d7534312bfe4a4a9 79 SUPERFAMILY SSF55021 6 77 2.71E-14 T 14-10-2018 C2I25_02415 80b754234266a6b7d7534312bfe4a4a9 79 Pfam PF13710 ACT domain 15 76 4.0E-14 T 14-10-2018 C2I25_02415 80b754234266a6b7d7534312bfe4a4a9 79 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 5 78 4.7E-16 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I25_02415 80b754234266a6b7d7534312bfe4a4a9 79 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 79 4.0E-39 T 14-10-2018 C2I25_02415 80b754234266a6b7d7534312bfe4a4a9 79 Gene3D G3DSA:3.30.70.260 4 79 2.0E-20 T 14-10-2018 C2I25_27000 c9fd8d4fecd5f94c663d8ae479ebc4b9 267 SUPERFAMILY SSF63817 15 225 6.93E-46 T 14-10-2018 IPR023365 Sortase domain superfamily C2I25_27000 c9fd8d4fecd5f94c663d8ae479ebc4b9 267 Gene3D G3DSA:2.40.260.10 29 240 1.6E-66 T 14-10-2018 IPR023365 Sortase domain superfamily C2I25_27000 c9fd8d4fecd5f94c663d8ae479ebc4b9 267 TIGRFAM TIGR01076 sortase_fam: sortase 97 230 7.2E-51 T 14-10-2018 IPR005754 Sortase family C2I25_27000 c9fd8d4fecd5f94c663d8ae479ebc4b9 267 Pfam PF04203 Sortase family 99 223 1.9E-24 T 14-10-2018 IPR005754 Sortase family C2I25_26725 b6d0b682807f077e061485a5343d2507 114 Gene3D G3DSA:1.10.260.40 3 113 1.4E-23 T 14-10-2018 C2I25_26725 b6d0b682807f077e061485a5343d2507 114 Pfam PF01381 Helix-turn-helix 7 61 3.6E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_26725 b6d0b682807f077e061485a5343d2507 114 SMART SM00530 6 61 4.4E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_26725 b6d0b682807f077e061485a5343d2507 114 SUPERFAMILY SSF47413 1 64 4.56E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_05215 a4c2a3edb12c2034a8336d64bf01a765 341 SUPERFAMILY SSF47648 1 67 2.35E-15 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_05215 a4c2a3edb12c2034a8336d64bf01a765 341 Gene3D G3DSA:1.20.970.10 3 67 1.7E-19 T 14-10-2018 C2I25_05215 a4c2a3edb12c2034a8336d64bf01a765 341 SUPERFAMILY SSF52418 73 338 3.01E-90 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_05215 a4c2a3edb12c2034a8336d64bf01a765 341 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 328 6.9E-116 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 C2I25_05215 a4c2a3edb12c2034a8336d64bf01a765 341 Pfam PF00591 Glycosyl transferase family, a/b domain 73 323 1.9E-91 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_05215 a4c2a3edb12c2034a8336d64bf01a765 341 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 37.215 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 C2I25_05215 a4c2a3edb12c2034a8336d64bf01a765 341 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 64 1.1E-15 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_05215 a4c2a3edb12c2034a8336d64bf01a765 341 Gene3D G3DSA:3.40.1030.10 70 338 7.3E-103 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I25_08945 a4e7128384776939448ecfc02b7d95d8 434 Pfam PF00202 Aminotransferase class-III 38 404 4.4E-71 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_08945 a4e7128384776939448ecfc02b7d95d8 434 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 430 95.276 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 C2I25_08945 a4e7128384776939448ecfc02b7d95d8 434 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I25_08945 a4e7128384776939448ecfc02b7d95d8 434 SUPERFAMILY SSF53383 4 428 2.48E-123 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_08945 a4e7128384776939448ecfc02b7d95d8 434 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 7 428 1.0E-168 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 C2I25_08945 a4e7128384776939448ecfc02b7d95d8 434 Gene3D G3DSA:3.90.1150.10 11 425 1.6E-170 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_08945 a4e7128384776939448ecfc02b7d95d8 434 Gene3D G3DSA:3.40.640.10 74 322 1.6E-170 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_18530 315aba6c0bd23d6ac89395c38788efe1 121 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 2 104 1.1E-13 T 14-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family C2I25_18530 315aba6c0bd23d6ac89395c38788efe1 121 Pfam PF05119 Phage terminase, small subunit 11 103 4.2E-9 T 14-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family C2I25_15790 b31e32c5f6b1a3bf5e5fd428f40af2fb 270 PIRSF PIRSF012562 1 264 3.1E-138 T 14-10-2018 IPR010838 Protein of unknown unction DUF1444 C2I25_15790 b31e32c5f6b1a3bf5e5fd428f40af2fb 270 Hamap MF_01548 UPF0354 protein . 3 264 48.366 T 14-10-2018 IPR010838 Protein of unknown unction DUF1444 C2I25_15790 b31e32c5f6b1a3bf5e5fd428f40af2fb 270 Pfam PF07285 Protein of unknown function (DUF1444) 3 263 9.1E-122 T 14-10-2018 IPR010838 Protein of unknown unction DUF1444 C2I25_16345 5396fbf2cf6f1ceb8764b8e621e3c628 157 Gene3D G3DSA:3.10.129.10 9 157 5.3E-28 T 14-10-2018 C2I25_16345 5396fbf2cf6f1ceb8764b8e621e3c628 157 Pfam PF01575 MaoC like domain 24 124 5.6E-9 T 14-10-2018 IPR002539 MaoC-like dehydratase domain C2I25_16345 5396fbf2cf6f1ceb8764b8e621e3c628 157 SUPERFAMILY SSF54637 8 144 1.92E-23 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_14480 8e25bf1dd28e32250f6501e30eb29e9d 117 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 114 4.7E-22 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_14480 8e25bf1dd28e32250f6501e30eb29e9d 117 Gene3D G3DSA:2.40.50.480 21 117 5.8E-40 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_14480 8e25bf1dd28e32250f6501e30eb29e9d 117 SUPERFAMILY SSF159121 20 116 7.06E-31 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_14480 8e25bf1dd28e32250f6501e30eb29e9d 117 Pfam PF06486 Protein of unknown function (DUF1093) 24 104 8.5E-27 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_06170 244c52274db073c9f08b9e04257c549c 247 SMART SM00382 29 213 1.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_06170 244c52274db073c9f08b9e04257c549c 247 Pfam PF00005 ABC transporter 20 163 1.3E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_06170 244c52274db073c9f08b9e04257c549c 247 Gene3D G3DSA:3.40.50.300 3 246 3.3E-65 T 14-10-2018 C2I25_06170 244c52274db073c9f08b9e04257c549c 247 SUPERFAMILY SSF52540 4 231 9.99E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_28385 e976fbb8be5e170afe3c8f1ac8d34cb8 176 Gene3D G3DSA:3.40.630.30 2 169 1.9E-48 T 14-10-2018 C2I25_28385 e976fbb8be5e170afe3c8f1ac8d34cb8 176 SUPERFAMILY SSF55729 3 173 1.58E-47 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_28385 e976fbb8be5e170afe3c8f1ac8d34cb8 176 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 5.8E-33 T 14-10-2018 IPR000182 GNAT domain C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 SUPERFAMILY SSF51569 1 291 6.28E-87 T 14-10-2018 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 SMART SM01130 3 293 3.2E-103 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 Pfam PF00701 Dihydrodipicolinate synthetase family 4 291 7.2E-72 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 PIRSF PIRSF001365 1 298 5.1E-96 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 9 290 8.8E-71 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 1.2E-20 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 1.2E-20 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 1.2E-20 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 1.2E-20 T 14-10-2018 IPR002220 DapA-like GO:0016829 C2I25_25420 f6520f7f5aa289c0514968ed1011f8a3 298 Gene3D G3DSA:3.20.20.70 1 294 7.2E-94 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 14-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 Pfam PF01165 Ribosomal protein S21 5 57 5.2E-21 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 9.0E-16 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 9.0E-16 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 9.0E-16 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 9.0E-16 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 1.6E-21 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 Gene3D G3DSA:1.20.5.1150 16 56 3.1E-18 T 14-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.633 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17735 26ae892bde23897c189a91b0a25be68e 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 1.0E-8 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_08400 cb564676f8260a78e776bf094a03baca 273 SUPERFAMILY SSF52540 4 232 2.88E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08400 cb564676f8260a78e776bf094a03baca 273 Gene3D G3DSA:3.40.50.300 1 252 8.2E-70 T 14-10-2018 C2I25_08400 cb564676f8260a78e776bf094a03baca 273 SMART SM00382 29 249 5.8E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08400 cb564676f8260a78e776bf094a03baca 273 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_08400 cb564676f8260a78e776bf094a03baca 273 Pfam PF00005 ABC transporter 21 168 9.6E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 801 0.0 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Pfam PF09334 tRNA synthetases class I (M) 39 170 1.8E-17 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 1.7E-20 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 SUPERFAMILY SSF50677 224 410 8.58E-56 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 SUPERFAMILY SSF52374 2 625 4.17E-146 T 14-10-2018 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Gene3D G3DSA:1.10.730.10 599 740 8.5E-48 T 14-10-2018 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Pfam PF08264 Anticodon-binding domain of tRNA 651 766 5.1E-22 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 SUPERFAMILY SSF47323 618 801 1.87E-43 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Gene3D G3DSA:2.30.210.10 572 587 5.2E-283 T 14-10-2018 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 2.0E-70 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Gene3D G3DSA:3.40.50.620 32 571 5.2E-283 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 801 23.294 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Gene3D G3DSA:3.10.20.590 744 801 8.0E-19 T 14-10-2018 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 Gene3D G3DSA:3.90.740.10 226 410 5.2E-283 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 1.2E-57 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 1.2E-57 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 1.2E-57 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 1.2E-57 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 1.2E-57 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 1.2E-57 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 1.2E-57 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I25_15555 ccb49ed18f3f574414653381af799a15 802 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_27845 62c454c741be8d030f2274da2465ab1c 584 Pfam PF00005 ABC transporter 352 501 7.2E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_27845 62c454c741be8d030f2274da2465ab1c 584 Gene3D G3DSA:1.20.1560.10 1 316 6.1E-90 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_27845 62c454c741be8d030f2274da2465ab1c 584 SUPERFAMILY SSF90123 5 318 7.19E-72 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_27845 62c454c741be8d030f2274da2465ab1c 584 Gene3D G3DSA:3.40.50.300 325 578 4.5E-84 T 14-10-2018 C2I25_27845 62c454c741be8d030f2274da2465ab1c 584 SMART SM00382 361 547 2.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_27845 62c454c741be8d030f2274da2465ab1c 584 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_27845 62c454c741be8d030f2274da2465ab1c 584 Pfam PF00664 ABC transporter transmembrane region 19 289 2.7E-44 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_27845 62c454c741be8d030f2274da2465ab1c 584 SUPERFAMILY SSF52540 325 571 3.63E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_08560 bd09aeb8638e4f3fd9624a275359dab9 223 SUPERFAMILY SSF46894 120 221 6.52E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_08560 bd09aeb8638e4f3fd9624a275359dab9 223 SUPERFAMILY SSF52172 1 120 9.39E-42 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_08560 bd09aeb8638e4f3fd9624a275359dab9 223 Gene3D G3DSA:3.40.50.2300 2 122 5.0E-39 T 14-10-2018 C2I25_08560 bd09aeb8638e4f3fd9624a275359dab9 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 4.4E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_08560 bd09aeb8638e4f3fd9624a275359dab9 223 SMART SM00448 2 112 6.5E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_08560 bd09aeb8638e4f3fd9624a275359dab9 223 Gene3D G3DSA:1.10.10.10 123 223 2.2E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_08560 bd09aeb8638e4f3fd9624a275359dab9 223 Pfam PF00072 Response regulator receiver domain 4 113 1.1E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_08560 bd09aeb8638e4f3fd9624a275359dab9 223 SMART SM00862 143 220 1.4E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 SMART SM00116 10 58 2.2E-12 T 14-10-2018 IPR000644 CBS domain C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 SMART SM00116 81 128 3.2E-9 T 14-10-2018 IPR000644 CBS domain C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 SUPERFAMILY SSF55021 137 206 5.6E-11 T 14-10-2018 C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 SUPERFAMILY SSF54631 1 130 4.42E-31 T 14-10-2018 C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 Pfam PF00571 CBS domain 3 56 2.8E-16 T 14-10-2018 IPR000644 CBS domain C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 Pfam PF00571 CBS domain 77 128 4.2E-9 T 14-10-2018 IPR000644 CBS domain C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 Pfam PF01842 ACT domain 139 199 2.5E-10 T 14-10-2018 IPR002912 ACT domain C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 Gene3D G3DSA:3.30.70.260 133 204 4.9E-7 T 14-10-2018 C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 Gene3D G3DSA:3.10.580.10 1 132 4.1E-34 T 14-10-2018 C2I25_15955 3205e4b6dedc1c501c2ec5a462d96ca5 214 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 140 205 0.006 T 14-10-2018 C2I25_23665 370bf8547d8b941e3f6bba3ee5fe44ca 253 Gene3D G3DSA:3.40.50.300 3 251 6.1E-66 T 14-10-2018 C2I25_23665 370bf8547d8b941e3f6bba3ee5fe44ca 253 Pfam PF00005 ABC transporter 26 174 1.2E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_23665 370bf8547d8b941e3f6bba3ee5fe44ca 253 SUPERFAMILY SSF52540 6 228 1.01E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23665 370bf8547d8b941e3f6bba3ee5fe44ca 253 SMART SM00382 35 234 1.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_10680 1e303caf7a980f440183136d06e5e8f6 495 Pfam PF07949 YbbR-like protein 54 132 3.0E-10 T 14-10-2018 IPR012505 YbbR-like C2I25_10680 1e303caf7a980f440183136d06e5e8f6 495 Pfam PF07949 YbbR-like protein 240 319 4.0E-17 T 14-10-2018 IPR012505 YbbR-like C2I25_10680 1e303caf7a980f440183136d06e5e8f6 495 Pfam PF07949 YbbR-like protein 335 416 6.9E-7 T 14-10-2018 IPR012505 YbbR-like C2I25_10680 1e303caf7a980f440183136d06e5e8f6 495 Pfam PF07949 YbbR-like protein 142 225 1.8E-11 T 14-10-2018 IPR012505 YbbR-like C2I25_10680 1e303caf7a980f440183136d06e5e8f6 495 Gene3D G3DSA:2.170.120.40 236 321 9.8E-21 T 14-10-2018 C2I25_10680 1e303caf7a980f440183136d06e5e8f6 495 Gene3D G3DSA:2.170.120.40 143 229 1.6E-10 T 14-10-2018 C2I25_10680 1e303caf7a980f440183136d06e5e8f6 495 Gene3D G3DSA:2.170.120.30 322 427 4.3E-14 T 14-10-2018 C2I25_10680 1e303caf7a980f440183136d06e5e8f6 495 Gene3D G3DSA:2.170.120.30 40 142 1.2E-20 T 14-10-2018 C2I25_16190 93706a4f59434babac5dda34f15d288d 110 SUPERFAMILY SSF51182 15 97 1.11E-17 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_16190 93706a4f59434babac5dda34f15d288d 110 Pfam PF07883 Cupin domain 40 88 5.7E-14 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_16190 93706a4f59434babac5dda34f15d288d 110 Gene3D G3DSA:2.60.120.10 1 103 1.7E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_08550 88db8910853cb2b1e7603240b699c694 168 Gene3D G3DSA:3.40.630.30 1 167 3.6E-42 T 14-10-2018 C2I25_08550 88db8910853cb2b1e7603240b699c694 168 Pfam PF13420 Acetyltransferase (GNAT) domain 3 159 4.1E-19 T 14-10-2018 C2I25_08550 88db8910853cb2b1e7603240b699c694 168 SUPERFAMILY SSF55729 1 167 3.04E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 SUPERFAMILY SSF51735 2 251 1.16E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 2.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 252 2.3E-39 T 14-10-2018 C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 Gene3D G3DSA:3.40.50.720 2 252 3.7E-56 T 14-10-2018 C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_23175 d106226af43e373d6d496d4e5a6fe991 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 Gene3D G3DSA:3.40.50.10490 1 44 5.9E-18 T 14-10-2018 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 SUPERFAMILY SSF53697 6 448 2.49E-143 T 14-10-2018 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 Pfam PF00342 Phosphoglucose isomerase 77 426 1.2E-20 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 Gene3D G3DSA:3.40.50.10490 225 418 7.9E-83 T 14-10-2018 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 2 436 26.516 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 4.4E-27 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 4.4E-27 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 4.4E-27 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 4.4E-27 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 4.4E-27 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 4.4E-27 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 Gene3D G3DSA:3.40.50.10490 45 224 2.7E-79 T 14-10-2018 C2I25_14655 268e464bc1742ea13bc11a91b2629282 450 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I25_19890 43d2aa78e9a572669b5bcce3a1878a4e 157 Gene3D G3DSA:3.40.630.30 2 157 3.8E-48 T 14-10-2018 C2I25_19890 43d2aa78e9a572669b5bcce3a1878a4e 157 PIRSF PIRSF037732 1 157 1.9E-78 T 14-10-2018 IPR017274 Putative N-acetyltransferase YlbP C2I25_19890 43d2aa78e9a572669b5bcce3a1878a4e 157 Pfam PF00583 Acetyltransferase (GNAT) family 35 107 1.3E-5 T 14-10-2018 IPR000182 GNAT domain C2I25_19890 43d2aa78e9a572669b5bcce3a1878a4e 157 Hamap MF_00824 Uncharacterized N-acetyltransferase . 3 144 38.132 T 14-10-2018 IPR017274 Putative N-acetyltransferase YlbP C2I25_19890 43d2aa78e9a572669b5bcce3a1878a4e 157 SUPERFAMILY SSF55729 33 145 1.16E-11 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24845 6fa77bcf768a7c732d5dff2209b699ef 657 Pfam PF00884 Sulfatase 253 541 1.6E-39 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I25_24845 6fa77bcf768a7c732d5dff2209b699ef 657 PIRSF PIRSF005091 1 626 3.3E-195 T 14-10-2018 IPR012160 Lipoteichoic acid synthase-like C2I25_24845 6fa77bcf768a7c732d5dff2209b699ef 657 Gene3D G3DSA:3.40.720.10 244 552 1.2E-82 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_24845 6fa77bcf768a7c732d5dff2209b699ef 657 SUPERFAMILY SSF53649 250 644 1.66E-83 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_24705 7cc8a213655bfec9f7d51af1f0fc7a49 347 Gene3D G3DSA:3.40.50.2300 136 347 6.8E-106 T 14-10-2018 C2I25_24705 7cc8a213655bfec9f7d51af1f0fc7a49 347 Pfam PF13407 Periplasmic binding protein domain 36 294 6.2E-55 T 14-10-2018 IPR025997 Periplasmic binding protein C2I25_24705 7cc8a213655bfec9f7d51af1f0fc7a49 347 Gene3D G3DSA:3.40.50.2300 36 331 6.8E-106 T 14-10-2018 C2I25_24705 7cc8a213655bfec9f7d51af1f0fc7a49 347 SUPERFAMILY SSF53822 34 347 2.03E-80 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_13060 52263d56d44d4cae462f9df362460345 121 PIRSF PIRSF031804 1 110 5.2E-43 T 14-10-2018 IPR016983 Uncharacterised conserved protein UCP031804 C2I25_13060 52263d56d44d4cae462f9df362460345 121 Pfam PF06803 Protein of unknown function (DUF1232) 45 80 1.4E-13 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 Hamap MF_01685 Ferredoxin--NADP reductase. 9 330 44.728 T 14-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 Gene3D G3DSA:3.50.50.60 9 306 1.8E-120 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 Gene3D G3DSA:3.50.50.60 130 248 1.8E-120 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 295 7.1E-30 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 SUPERFAMILY SSF51905 10 316 1.04E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 9.9E-19 T 14-10-2018 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 9.9E-19 T 14-10-2018 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 9.9E-19 T 14-10-2018 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 9.9E-19 T 14-10-2018 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 1.8E-23 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 78 1.8E-23 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 1.8E-23 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 1.8E-23 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_14510 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 1.8E-23 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_14195 725589aa4c2127a836fd8aace93e0b33 406 Gene3D G3DSA:3.90.1150.10 6 395 9.9E-185 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_14195 725589aa4c2127a836fd8aace93e0b33 406 Pfam PF00266 Aminotransferase class-V 23 391 1.6E-164 T 14-10-2018 IPR000192 Aminotransferase class V domain C2I25_14195 725589aa4c2127a836fd8aace93e0b33 406 SUPERFAMILY SSF53383 2 398 1.43E-133 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_14195 725589aa4c2127a836fd8aace93e0b33 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site C2I25_14195 725589aa4c2127a836fd8aace93e0b33 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 402 4.4E-192 T 14-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I25_14195 725589aa4c2127a836fd8aace93e0b33 406 Gene3D G3DSA:3.40.640.10 34 294 9.9E-185 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_14195 725589aa4c2127a836fd8aace93e0b33 406 PIRSF PIRSF005572 20 404 6.1E-56 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I25_02870 97651161e7bb4fbb7ba1df5c0de50964 305 Gene3D G3DSA:3.40.50.1820 20 299 1.3E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_02870 97651161e7bb4fbb7ba1df5c0de50964 305 SUPERFAMILY SSF53474 6 295 8.58E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_02870 97651161e7bb4fbb7ba1df5c0de50964 305 Pfam PF00561 alpha/beta hydrolase fold 35 152 1.1E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_02870 97651161e7bb4fbb7ba1df5c0de50964 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 1.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_02870 97651161e7bb4fbb7ba1df5c0de50964 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_02870 97651161e7bb4fbb7ba1df5c0de50964 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_25945 ad6b56088b3b1c735c706fbf1829c58f 333 Gene3D G3DSA:3.40.50.1820 48 322 1.1E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_25945 ad6b56088b3b1c735c706fbf1829c58f 333 Pfam PF09752 Abhydrolase domain containing 18 131 201 1.5E-4 T 14-10-2018 IPR019149 Abhydrolase domain containing 18 C2I25_25945 ad6b56088b3b1c735c706fbf1829c58f 333 SUPERFAMILY SSF53474 80 324 1.76E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_08115 c176442851dffbd1536b46985021dd20 283 SMART SM00770 1 283 1.7E-130 T 14-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 C2I25_08115 c176442851dffbd1536b46985021dd20 283 ProSitePatterns PS00384 Prokaryotic zinc-dependent phospholipase C signature. 156 169 - T 14-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 C2I25_08115 c176442851dffbd1536b46985021dd20 283 SUPERFAMILY SSF48537 39 281 2.49E-63 T 14-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 C2I25_08115 c176442851dffbd1536b46985021dd20 283 ProDom PD003946 PHOSPHOLIPASE C PLCB HYDROLASE PRECURSOR PHOSPHATIDYLCHOLINE SIGNAL CHOLINEPHOSPHOHYDROLASE TOXIN PLC 47 275 8.0E-134 T 14-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 C2I25_08115 c176442851dffbd1536b46985021dd20 283 Pfam PF00882 Zinc dependent phospholipase C 51 230 7.0E-21 T 14-10-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 C2I25_08115 c176442851dffbd1536b46985021dd20 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 107 120 7.1E-28 T 14-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 C2I25_08115 c176442851dffbd1536b46985021dd20 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 130 152 7.1E-28 T 14-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 C2I25_08115 c176442851dffbd1536b46985021dd20 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 153 177 7.1E-28 T 14-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 C2I25_08115 c176442851dffbd1536b46985021dd20 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 180 197 7.1E-28 T 14-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 C2I25_08115 c176442851dffbd1536b46985021dd20 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 266 276 7.1E-28 T 14-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 C2I25_08115 c176442851dffbd1536b46985021dd20 283 Gene3D G3DSA:1.10.575.10 39 283 3.4E-108 T 14-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 Gene3D G3DSA:3.40.1830.10 1 179 1.1E-70 T 14-10-2018 IPR035097 Peptidase M29, N-terminal C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 Pfam PF02073 Thermophilic metalloprotease (M29) 4 407 7.4E-177 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 SUPERFAMILY SSF144052 3 408 8.24E-153 T 14-10-2018 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 14 31 3.8E-74 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 362 384 3.8E-74 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 244 263 3.8E-74 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 300 320 3.8E-74 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 155 177 3.8E-74 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 79 98 3.8E-74 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 388 407 3.8E-74 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_09720 4801d600dbb025e9338ac2f746ecafb4 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 323 344 3.8E-74 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_24075 055dbd9335bb7a6c6611d65d49f82973 385 SUPERFAMILY SSF56601 61 373 1.66E-78 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_24075 055dbd9335bb7a6c6611d65d49f82973 385 Pfam PF00144 Beta-lactamase 62 379 1.7E-65 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_24075 055dbd9335bb7a6c6611d65d49f82973 385 Gene3D G3DSA:3.40.710.10 47 385 5.4E-134 T 14-10-2018 C2I25_24645 0c41051b8e1803670d0333cb5960c411 347 SUPERFAMILY SSF46785 268 345 3.71E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_24645 0c41051b8e1803670d0333cb5960c411 347 Pfam PF01022 Bacterial regulatory protein, arsR family 276 320 6.9E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_24645 0c41051b8e1803670d0333cb5960c411 347 Gene3D G3DSA:1.10.10.10 261 345 3.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_24645 0c41051b8e1803670d0333cb5960c411 347 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 303 318 2.0E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_24645 0c41051b8e1803670d0333cb5960c411 347 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 271 286 2.0E-5 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_24645 0c41051b8e1803670d0333cb5960c411 347 SMART SM00418 269 342 8.7E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_23210 e4e90d59039ee8d54e7b7921e0402e1f 126 Pfam PF01638 HxlR-like helix-turn-helix 27 115 2.3E-39 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_23210 e4e90d59039ee8d54e7b7921e0402e1f 126 SUPERFAMILY SSF46785 15 119 5.05E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23210 e4e90d59039ee8d54e7b7921e0402e1f 126 Gene3D G3DSA:1.10.10.10 4 126 1.3E-42 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_11230 bc86e035f7232d6316ea16d38b14414d 171 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 133 2.2E-39 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I25_11230 bc86e035f7232d6316ea16d38b14414d 171 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I25_11230 bc86e035f7232d6316ea16d38b14414d 171 SUPERFAMILY SSF55083 4 149 4.05E-53 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I25_11230 bc86e035f7232d6316ea16d38b14414d 171 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 1.1E-47 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I25_11230 bc86e035f7232d6316ea16d38b14414d 171 Gene3D G3DSA:3.30.70.560 2 170 1.6E-57 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 PIRSF PIRSF000102 2 316 1.2E-112 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 SUPERFAMILY SSF56327 146 314 2.51E-55 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 9.8E-120 T 14-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 315 44.725 T 14-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 14-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 312 7.6E-26 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 5.2E-43 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 Gene3D G3DSA:3.40.50.720 1 147 1.5E-56 T 14-10-2018 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 1.6E-44 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 1.6E-44 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 1.6E-44 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 1.6E-44 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 1.6E-44 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 Gene3D G3DSA:3.90.110.10 148 316 8.7E-58 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_14090 ea3fc6fc4c8322be15e7db35f7c2c2aa 316 SUPERFAMILY SSF51735 2 147 1.06E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_15050 9a54551b25bdace07380010254e69fed 649 Pfam PF02687 FtsX-like permease family 85 170 9.3E-10 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_15050 9a54551b25bdace07380010254e69fed 649 PIRSF PIRSF018968 1 649 4.0E-126 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_20475 e18d850046a6aade4438a2c3be2ebd28 89 Gene3D G3DSA:1.10.287.10 2 89 2.3E-37 T 14-10-2018 C2I25_20475 e18d850046a6aade4438a2c3be2ebd28 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-39 T 14-10-2018 C2I25_20475 e18d850046a6aade4438a2c3be2ebd28 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.161 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20475 e18d850046a6aade4438a2c3be2ebd28 89 SUPERFAMILY SSF47060 3 89 1.44E-36 T 14-10-2018 IPR009068 S15/NS1, RNA-binding C2I25_20475 e18d850046a6aade4438a2c3be2ebd28 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20475 e18d850046a6aade4438a2c3be2ebd28 89 Pfam PF00312 Ribosomal protein S15 8 88 7.0E-38 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20475 e18d850046a6aade4438a2c3be2ebd28 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 3.1E-42 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20475 e18d850046a6aade4438a2c3be2ebd28 89 SMART SM01387 8 88 2.1E-52 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_15935 f369b533542ed8c2eb861bc0b8238557 229 SUPERFAMILY SSF46894 128 228 5.67E-30 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_15935 f369b533542ed8c2eb861bc0b8238557 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 2.4E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_15935 f369b533542ed8c2eb861bc0b8238557 229 Pfam PF00072 Response regulator receiver domain 4 113 1.8E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_15935 f369b533542ed8c2eb861bc0b8238557 229 SMART SM00862 151 227 2.0E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_15935 f369b533542ed8c2eb861bc0b8238557 229 SMART SM00448 2 112 4.0E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_15935 f369b533542ed8c2eb861bc0b8238557 229 Gene3D G3DSA:1.10.10.10 130 229 4.7E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15935 f369b533542ed8c2eb861bc0b8238557 229 SUPERFAMILY SSF52172 3 130 7.12E-40 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_15935 f369b533542ed8c2eb861bc0b8238557 229 Gene3D G3DSA:3.40.50.2300 1 129 1.8E-36 T 14-10-2018 C2I25_02825 6c9f9424cc15f47dd1641a3f7b9420d6 56 Pfam PF13076 Fur-regulated basic protein A 12 46 3.0E-17 T 14-10-2018 IPR025072 Fur-regulated basic protein A C2I25_18370 740b13f6a9e9ade661ae887f8ead4f32 390 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 2 383 9.7E-162 T 14-10-2018 IPR014194 Sporulation stage III, protein AE C2I25_18370 740b13f6a9e9ade661ae887f8ead4f32 390 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 68 383 3.4E-109 T 14-10-2018 IPR014194 Sporulation stage III, protein AE C2I25_26105 e9565c2fd0ee163408a812b4e97f94b4 396 Pfam PF09350 Domain of unknown function (DUF1992) 295 356 7.5E-18 T 14-10-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain C2I25_26105 e9565c2fd0ee163408a812b4e97f94b4 396 SUPERFAMILY SSF53474 9 246 4.26E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_26105 e9565c2fd0ee163408a812b4e97f94b4 396 Pfam PF00756 Putative esterase 26 245 1.5E-36 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 C2I25_26105 e9565c2fd0ee163408a812b4e97f94b4 396 Gene3D G3DSA:3.40.50.1820 3 250 9.3E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_11735 a4886e6dfe5ff4b941f59eb47fc93c02 311 Pfam PF09991 Predicted membrane protein (DUF2232) 15 301 5.8E-81 T 14-10-2018 IPR018710 Protein of unknown function DUF2232 C2I25_11400 732305feb26a92a10d4ab29f491ea2f1 287 PIRSF PIRSF011575 2 286 9.9E-110 T 14-10-2018 IPR008764 Peptidase U57, YabG C2I25_11400 732305feb26a92a10d4ab29f491ea2f1 287 Pfam PF05582 YabG peptidase U57 5 281 6.7E-112 T 14-10-2018 IPR008764 Peptidase U57, YabG C2I25_11400 732305feb26a92a10d4ab29f491ea2f1 287 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 282 1.1E-138 T 14-10-2018 IPR008764 Peptidase U57, YabG C2I25_11400 732305feb26a92a10d4ab29f491ea2f1 287 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 3 276 4.0E-152 T 14-10-2018 IPR008764 Peptidase U57, YabG C2I25_17975 d21d69056bf710975c9181e3912f9401 327 Gene3D G3DSA:3.30.420.40 7 315 1.2E-110 T 14-10-2018 C2I25_17975 d21d69056bf710975c9181e3912f9401 327 Gene3D G3DSA:3.30.420.40 130 303 1.2E-110 T 14-10-2018 C2I25_17975 d21d69056bf710975c9181e3912f9401 327 Pfam PF00480 ROK family 7 319 1.1E-78 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I25_17975 d21d69056bf710975c9181e3912f9401 327 ProSitePatterns PS01125 ROK family signature. 139 166 - T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I25_17975 d21d69056bf710975c9181e3912f9401 327 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 323 3.7E-123 T 14-10-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 C2I25_17975 d21d69056bf710975c9181e3912f9401 327 SUPERFAMILY SSF53067 5 320 1.4E-70 T 14-10-2018 C2I25_19000 144fa12b305a3eb8047eaff141d558cb 90 Pfam PF14004 Protein of unknown function (DUF4227) 20 90 8.7E-29 T 14-10-2018 IPR025321 Protein of unknown function DUF4227 C2I25_09130 97a64d872fe5ad7cfdb317aca296c3d3 217 SMART SM00530 13 68 4.1E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_09130 97a64d872fe5ad7cfdb317aca296c3d3 217 SUPERFAMILY SSF47413 7 76 6.57E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_09130 97a64d872fe5ad7cfdb317aca296c3d3 217 Gene3D G3DSA:1.10.260.40 10 171 3.2E-14 T 14-10-2018 C2I25_09130 97a64d872fe5ad7cfdb317aca296c3d3 217 Pfam PF06803 Protein of unknown function (DUF1232) 170 203 2.5E-11 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 C2I25_09130 97a64d872fe5ad7cfdb317aca296c3d3 217 Pfam PF01381 Helix-turn-helix 14 68 1.5E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_07370 6b345740055af0c2f27c309d20f3df64 436 Pfam PF02378 Phosphotransferase system, EIIC 29 352 2.8E-59 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_07370 6b345740055af0c2f27c309d20f3df64 436 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 426 2.9E-119 T 14-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 C2I25_07370 6b345740055af0c2f27c309d20f3df64 436 PIRSF PIRSF006351 1 434 8.6E-141 T 14-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I25_19785 c92d344d815567a364a5a78e7d73aecc 207 Gene3D G3DSA:1.20.120.80 21 206 9.3E-53 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19785 c92d344d815567a364a5a78e7d73aecc 207 SUPERFAMILY SSF81452 21 204 3.01E-56 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_19785 c92d344d815567a364a5a78e7d73aecc 207 Pfam PF00510 Cytochrome c oxidase subunit III 28 204 8.0E-20 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_06455 587e62d8b2741e9728c57cf97c664f3c 66 SUPERFAMILY SSF69047 7 63 1.31E-11 T 14-10-2018 IPR036629 YjbJ superfamily C2I25_06455 587e62d8b2741e9728c57cf97c664f3c 66 Gene3D G3DSA:1.10.1470.10 7 66 1.3E-7 T 14-10-2018 IPR036629 YjbJ superfamily C2I25_06455 587e62d8b2741e9728c57cf97c664f3c 66 Pfam PF05532 CsbD-like 8 60 1.3E-14 T 14-10-2018 IPR008462 CsbD-like domain C2I25_14835 cb5fdecfd5ffb543ffa42edc1be1167f 344 Gene3D G3DSA:2.160.10.10 231 341 3.2E-28 T 14-10-2018 C2I25_14835 cb5fdecfd5ffb543ffa42edc1be1167f 344 SUPERFAMILY SSF51161 253 325 1.26E-15 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I25_14835 cb5fdecfd5ffb543ffa42edc1be1167f 344 Gene3D G3DSA:3.90.550.10 1 157 2.4E-23 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_14835 cb5fdecfd5ffb543ffa42edc1be1167f 344 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 289 322 5.9E-5 T 14-10-2018 IPR001451 Hexapeptide repeat C2I25_14835 cb5fdecfd5ffb543ffa42edc1be1167f 344 Pfam PF00483 Nucleotidyl transferase 8 149 1.3E-9 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_14835 cb5fdecfd5ffb543ffa42edc1be1167f 344 SUPERFAMILY SSF53448 4 301 2.25E-36 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 3.1E-156 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 93 108 - T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 Pfam PF01235 Sodium:alanine symporter family 56 450 9.2E-159 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 PRINTS PR00175 Sodium/alanine symporter signature 183 201 8.9E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 PRINTS PR00175 Sodium/alanine symporter signature 211 230 8.9E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 PRINTS PR00175 Sodium/alanine symporter signature 302 320 8.9E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 PRINTS PR00175 Sodium/alanine symporter signature 407 427 8.9E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 PRINTS PR00175 Sodium/alanine symporter signature 93 115 8.9E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_13770 90dee2283b83206177cccbc9cdddda79 476 PRINTS PR00175 Sodium/alanine symporter signature 347 369 8.9E-61 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_01660 45bb69898b9e6096fd0874761f8a40f9 321 Pfam PF01734 Patatin-like phospholipase 6 198 1.7E-31 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I25_01660 45bb69898b9e6096fd0874761f8a40f9 321 Gene3D G3DSA:3.40.1090.20 2 105 3.8E-21 T 14-10-2018 C2I25_01660 45bb69898b9e6096fd0874761f8a40f9 321 SUPERFAMILY SSF52151 6 303 2.49E-45 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 SUPERFAMILY SSF50249 3 125 1.3E-50 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 SUPERFAMILY SSF50104 126 273 9.03E-62 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 Gene3D G3DSA:4.10.950.10 197 276 2.7E-38 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.384 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 Gene3D G3DSA:2.30.30.30 118 196 1.3E-34 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 SMART SM01382 124 253 9.4E-94 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 4.2E-34 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 3.0E-141 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 Gene3D G3DSA:2.40.50.140 1 114 1.3E-48 T 14-10-2018 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 PIRSF PIRSF002158 3 276 1.7E-99 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 8.0E-58 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 C2I25_10955 032cab93f3c4297ac311de857fb197d4 276 SMART SM01383 42 118 2.2E-47 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 3.1E-65 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.208 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 Pfam PF00467 KOW motif 129 158 4.0E-5 T 14-10-2018 IPR005824 KOW C2I25_11045 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.1E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.1E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.1E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 Gene3D G3DSA:3.30.70.940 1 118 2.4E-44 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 Gene3D G3DSA:2.30.30.30 119 177 9.8E-24 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 14-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site C2I25_11045 e624392e043dda55457abed19b2a25d8 177 Pfam PF02357 Transcription termination factor nusG 3 109 1.0E-28 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 SMART SM00738 2 113 4.4E-51 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 C2I25_11045 e624392e043dda55457abed19b2a25d8 177 SUPERFAMILY SSF50104 121 177 1.35E-18 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I25_11045 e624392e043dda55457abed19b2a25d8 177 SUPERFAMILY SSF82679 2 114 3.53E-40 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 C2I25_20930 667882db8e3685677b663f8f39f7fc0b 387 SUPERFAMILY SSF56796 1 385 3.4E-118 T 14-10-2018 C2I25_20930 667882db8e3685677b663f8f39f7fc0b 387 Gene3D G3DSA:3.40.50.1970 1 184 4.7E-55 T 14-10-2018 C2I25_20930 667882db8e3685677b663f8f39f7fc0b 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I25_20930 667882db8e3685677b663f8f39f7fc0b 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 378 3.8E-101 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I25_20930 667882db8e3685677b663f8f39f7fc0b 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I25_20930 667882db8e3685677b663f8f39f7fc0b 387 Gene3D G3DSA:1.20.1090.10 185 386 2.7E-47 T 14-10-2018 C2I25_08235 8f4470ca225b466c4c5a37d04b79c721 483 Pfam PF00916 Sulfate permease family 149 354 4.0E-32 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I25_08235 8f4470ca225b466c4c5a37d04b79c721 483 Pfam PF00916 Sulfate permease family 14 139 7.1E-25 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I25_08235 8f4470ca225b466c4c5a37d04b79c721 483 Gene3D G3DSA:3.30.750.24 382 478 1.7E-26 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_08235 8f4470ca225b466c4c5a37d04b79c721 483 SUPERFAMILY SSF52091 387 471 2.35E-9 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_25835 4a090f18367c7e7a5d45d2d126d8518e 446 Pfam PF14620 YpeB sporulation 14 372 5.6E-138 T 14-10-2018 IPR014239 Spore germination YpeB GO:0009847 C2I25_25835 4a090f18367c7e7a5d45d2d126d8518e 446 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 438 1.7E-148 T 14-10-2018 IPR014239 Spore germination YpeB GO:0009847 C2I25_21075 704b8f6e864c8d843c39cc795a62f939 146 Pfam PF10747 Sporulation inhibitor of replication protein SirA 2 140 5.6E-42 T 14-10-2018 IPR019683 Sporulation inhibitor of replication protein SirA C2I25_21075 704b8f6e864c8d843c39cc795a62f939 146 Gene3D G3DSA:3.30.310.250 1 145 5.8E-42 T 14-10-2018 IPR038449 SirA superfamily C2I25_09400 9568de36de55906f21ff4c53f4911c19 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 257 4.9E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_09400 9568de36de55906f21ff4c53f4911c19 265 Gene3D G3DSA:1.10.3720.10 57 255 1.4E-23 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_09400 9568de36de55906f21ff4c53f4911c19 265 SUPERFAMILY SSF161098 61 246 1.14E-29 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_00315 be632bbc5d52c8bee3f07cc47e6d53c3 143 Pfam PF00583 Acetyltransferase (GNAT) family 43 132 6.8E-14 T 14-10-2018 IPR000182 GNAT domain C2I25_00315 be632bbc5d52c8bee3f07cc47e6d53c3 143 SUPERFAMILY SSF55729 1 139 1.99E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_00315 be632bbc5d52c8bee3f07cc47e6d53c3 143 Gene3D G3DSA:3.40.630.30 2 143 1.2E-29 T 14-10-2018 C2I25_05695 54e38cf48c2d002d1f51a5bd307f43cc 128 Pfam PF10970 Spore germination protein GerPE 5 128 5.0E-49 T 14-10-2018 IPR024496 Spore germination protein GerPE C2I25_05695 54e38cf48c2d002d1f51a5bd307f43cc 128 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 5 128 3.0E-66 T 14-10-2018 IPR024496 Spore germination protein GerPE C2I25_18000 3bd2ae98ed9843f4f2e1a2fb1ad8efdd 170 Gene3D G3DSA:3.40.50.850 5 168 1.3E-35 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_18000 3bd2ae98ed9843f4f2e1a2fb1ad8efdd 170 Pfam PF00857 Isochorismatase family 7 143 3.9E-31 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_18000 3bd2ae98ed9843f4f2e1a2fb1ad8efdd 170 SUPERFAMILY SSF52499 7 165 1.05E-37 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_09255 6ae12649678218b2b447fbed7935bdf9 288 PIRSF PIRSF035875 1 288 3.0E-91 T 14-10-2018 IPR017039 Virulence factor BrkB C2I25_09255 6ae12649678218b2b447fbed7935bdf9 288 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 15 278 1.4E-56 T 14-10-2018 IPR017039 Virulence factor BrkB C2I25_09255 6ae12649678218b2b447fbed7935bdf9 288 Pfam PF03631 Virulence factor BrkB 26 277 2.4E-67 T 14-10-2018 IPR017039 Virulence factor BrkB C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 7 355 2.9E-145 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 2.1E-33 T 14-10-2018 IPR025121 GTPase HflX, N-terminal C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 PIRSF PIRSF006809 1 415 7.6E-152 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 SUPERFAMILY SSF52540 197 364 1.77E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 Gene3D G3DSA:3.40.50.11060 19 138 1.4E-41 T 14-10-2018 C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 Hamap MF_00900 GTPase HflX [hflX]. 27 385 46.197 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 7.6E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 7.6E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 1.6E-30 T 14-10-2018 IPR032305 GTP-binding protein, middle domain C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 Gene3D G3DSA:3.40.50.300 199 365 4.0E-34 T 14-10-2018 C2I25_20995 200b15f5cad72c762d7432cc51b806d8 425 Pfam PF01926 50S ribosome-binding GTPase 200 318 4.6E-19 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_12745 f6cc210756b2c0ee387a2bfb7da39fa7 434 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 1.8E-176 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_12745 f6cc210756b2c0ee387a2bfb7da39fa7 434 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.533 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_12745 f6cc210756b2c0ee387a2bfb7da39fa7 434 Gene3D G3DSA:3.65.10.10 21 231 4.6E-178 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I25_12745 f6cc210756b2c0ee387a2bfb7da39fa7 434 Gene3D G3DSA:3.65.10.10 7 414 4.6E-178 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I25_12745 f6cc210756b2c0ee387a2bfb7da39fa7 434 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 407 2.6E-117 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 C2I25_12745 f6cc210756b2c0ee387a2bfb7da39fa7 434 SUPERFAMILY SSF55205 2 418 9.65E-143 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 C2I25_01375 8cd0da02c8b786695609e33826043f73 435 SUPERFAMILY SSF54631 204 338 1.17E-27 T 14-10-2018 C2I25_01375 8cd0da02c8b786695609e33826043f73 435 Pfam PF03471 Transporter associated domain 359 429 8.8E-15 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_01375 8cd0da02c8b786695609e33826043f73 435 SUPERFAMILY SSF56176 349 429 1.15E-14 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_01375 8cd0da02c8b786695609e33826043f73 435 SMART SM01091 351 430 4.0E-16 T 14-10-2018 IPR005170 Transporter-associated domain C2I25_01375 8cd0da02c8b786695609e33826043f73 435 Pfam PF01595 Domain of unknown function DUF21 7 201 5.3E-49 T 14-10-2018 IPR002550 CNNM, transmembrane domain C2I25_01375 8cd0da02c8b786695609e33826043f73 435 Pfam PF00571 CBS domain 217 266 0.0024 T 14-10-2018 IPR000644 CBS domain C2I25_01375 8cd0da02c8b786695609e33826043f73 435 Pfam PF00571 CBS domain 286 334 3.0E-4 T 14-10-2018 IPR000644 CBS domain C2I25_01375 8cd0da02c8b786695609e33826043f73 435 Gene3D G3DSA:3.30.465.10 346 434 3.4E-16 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_01375 8cd0da02c8b786695609e33826043f73 435 Gene3D G3DSA:3.10.580.10 195 345 4.3E-49 T 14-10-2018 C2I25_26320 fbf56d56d232345d1b8fb2dbade13452 329 SUPERFAMILY SSF50129 1 162 2.99E-28 T 14-10-2018 IPR011032 GroES-like superfamily C2I25_26320 fbf56d56d232345d1b8fb2dbade13452 329 Gene3D G3DSA:3.40.50.720 139 276 4.8E-86 T 14-10-2018 C2I25_26320 fbf56d56d232345d1b8fb2dbade13452 329 Pfam PF00107 Zinc-binding dehydrogenase 169 291 2.1E-28 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I25_26320 fbf56d56d232345d1b8fb2dbade13452 329 Gene3D G3DSA:3.90.180.10 21 318 4.8E-86 T 14-10-2018 C2I25_26320 fbf56d56d232345d1b8fb2dbade13452 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 124 3.4E-12 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I25_26320 fbf56d56d232345d1b8fb2dbade13452 329 SUPERFAMILY SSF51735 130 299 3.71E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_26320 fbf56d56d232345d1b8fb2dbade13452 329 SMART SM00829 11 326 3.0E-12 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I25_13600 cd8917347aa2f6fd4d13c584f9765c78 255 SUPERFAMILY SSF55729 130 254 1.74E-16 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_13600 cd8917347aa2f6fd4d13c584f9765c78 255 Gene3D G3DSA:3.40.630.30 44 253 8.8E-23 T 14-10-2018 C2I25_13600 cd8917347aa2f6fd4d13c584f9765c78 255 Pfam PF13673 Acetyltransferase (GNAT) domain 170 253 6.7E-9 T 14-10-2018 IPR000182 GNAT domain C2I25_07300 225fc6e82e300ec23f21bcb1ef6ef108 71 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 5 71 2.0E-32 T 14-10-2018 IPR020256 Spore coat protein CotJA C2I25_07300 225fc6e82e300ec23f21bcb1ef6ef108 71 Pfam PF11007 Spore coat associated protein JA (CotJA) 28 63 1.3E-10 T 14-10-2018 IPR020256 Spore coat protein CotJA C2I25_17940 fbefa0390da64292d45fcd2bcf76a076 271 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_17940 fbefa0390da64292d45fcd2bcf76a076 271 SUPERFAMILY SSF52540 20 258 3.87E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17940 fbefa0390da64292d45fcd2bcf76a076 271 Gene3D G3DSA:3.40.50.300 22 267 7.4E-63 T 14-10-2018 C2I25_17940 fbefa0390da64292d45fcd2bcf76a076 271 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 25 271 3.4E-126 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 C2I25_17940 fbefa0390da64292d45fcd2bcf76a076 271 SMART SM00382 49 258 7.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_17940 fbefa0390da64292d45fcd2bcf76a076 271 Pfam PF00005 ABC transporter 40 196 3.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_25250 cf950ceb535286cbea36ea95cbf77507 237 SUPERFAMILY SSF53167 3 228 6.81E-62 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I25_25250 cf950ceb535286cbea36ea95cbf77507 237 Gene3D G3DSA:3.40.50.1580 1 231 3.2E-61 T 14-10-2018 C2I25_25250 cf950ceb535286cbea36ea95cbf77507 237 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 227 1.6E-51 T 14-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I25_25250 cf950ceb535286cbea36ea95cbf77507 237 Pfam PF01048 Phosphorylase superfamily 3 224 3.4E-49 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I25_21560 f72905d4c8b8945668f4897ba0f2434b 137 SMART SM00881 15 107 2.0E-19 T 14-10-2018 IPR003781 CoA-binding GO:0048037 C2I25_21560 f72905d4c8b8945668f4897ba0f2434b 137 Gene3D G3DSA:3.40.50.720 1 137 2.4E-39 T 14-10-2018 C2I25_21560 f72905d4c8b8945668f4897ba0f2434b 137 SUPERFAMILY SSF51735 9 136 7.38E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_21560 f72905d4c8b8945668f4897ba0f2434b 137 Pfam PF13380 CoA binding domain 19 133 5.3E-38 T 14-10-2018 IPR003781 CoA-binding GO:0048037 C2I25_05170 72518613eea92e1c3770c8f1af72f715 261 Pfam PF13240 zinc-ribbon domain 2 24 6.8E-7 T 14-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 C2I25_02740 c323401269fe742e9d3a0b424a1bbdee 232 Pfam PF03575 Peptidase family S51 3 203 2.7E-60 T 14-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 C2I25_02740 c323401269fe742e9d3a0b424a1bbdee 232 SUPERFAMILY SSF52317 1 204 4.76E-31 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_02740 c323401269fe742e9d3a0b424a1bbdee 232 Gene3D G3DSA:3.40.50.880 8 219 2.2E-41 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_24285 b29b48b7a5dff022cfbdf5a568e6a36f 163 ProDom PD095338 YXII PLASMID 1 158 5.0E-86 T 14-10-2018 IPR020323 Protein of unknown function DUF2716 C2I25_24285 b29b48b7a5dff022cfbdf5a568e6a36f 163 Pfam PF10898 Protein of unknown function (DUF2716) 6 145 1.4E-55 T 14-10-2018 IPR020323 Protein of unknown function DUF2716 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 287 5.4E-84 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 Gene3D G3DSA:3.40.710.10 29 307 7.3E-91 T 14-10-2018 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 SUPERFAMILY SSF56601 4 307 2.09E-78 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 Gene3D G3DSA:2.60.410.10 308 409 2.4E-14 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 SUPERFAMILY SSF69189 299 391 1.45E-15 T 14-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 307 409 7.0E-13 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 4.0E-13 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 4.0E-13 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 4.0E-13 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_27435 36e30633afa9214ad528bbe387116d5a 437 SMART SM00936 307 409 5.6E-15 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_22055 c49e2b15377dda6c06e40c3527c56e7f 375 Gene3D G3DSA:3.30.300.210 215 374 1.3E-26 T 14-10-2018 IPR038501 Spore germination GerAC superfamily C2I25_22055 c49e2b15377dda6c06e40c3527c56e7f 375 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 374 1.2E-65 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_22055 c49e2b15377dda6c06e40c3527c56e7f 375 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 197 371 9.3E-26 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_14155 9d72b3d75401145b95a455f86ef02bec 102 Pfam PF00085 Thioredoxin 14 90 1.7E-9 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I25_14155 9d72b3d75401145b95a455f86ef02bec 102 SUPERFAMILY SSF52833 4 100 1.77E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_14155 9d72b3d75401145b95a455f86ef02bec 102 Gene3D G3DSA:3.40.30.10 8 102 1.3E-14 T 14-10-2018 C2I25_07595 e295508c859359946854554c8fc27034 494 Pfam PF00005 ABC transporter 19 171 6.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_07595 e295508c859359946854554c8fc27034 494 SUPERFAMILY SSF52540 272 475 2.81E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07595 e295508c859359946854554c8fc27034 494 SUPERFAMILY SSF52540 4 231 9.84E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07595 e295508c859359946854554c8fc27034 494 Gene3D G3DSA:3.40.50.300 2 262 5.7E-54 T 14-10-2018 C2I25_07595 e295508c859359946854554c8fc27034 494 Gene3D G3DSA:3.40.50.300 263 487 5.3E-36 T 14-10-2018 C2I25_07595 e295508c859359946854554c8fc27034 494 SMART SM00382 279 465 9.9E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_07595 e295508c859359946854554c8fc27034 494 SMART SM00382 28 219 3.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_07595 e295508c859359946854554c8fc27034 494 Pfam PF00005 ABC transporter 272 416 2.7E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_09105 e7eebd9d1b208db0bd8d5b278be4b278 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 309 5.0E-125 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I25_09105 e7eebd9d1b208db0bd8d5b278be4b278 309 Gene3D G3DSA:3.40.710.10 3 309 2.9E-111 T 14-10-2018 C2I25_09105 e7eebd9d1b208db0bd8d5b278be4b278 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 47.277 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I25_09105 e7eebd9d1b208db0bd8d5b278be4b278 309 SUPERFAMILY SSF56601 6 309 5.45E-114 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_09105 e7eebd9d1b208db0bd8d5b278be4b278 309 Pfam PF04960 Glutaminase 23 309 4.9E-112 T 14-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 PRINTS PR00094 Adenylate kinase signature 4 17 9.1E-33 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 PRINTS PR00094 Adenylate kinase signature 177 191 9.1E-33 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 PRINTS PR00094 Adenylate kinase signature 81 97 9.1E-33 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 PRINTS PR00094 Adenylate kinase signature 160 175 9.1E-33 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 PRINTS PR00094 Adenylate kinase signature 32 46 9.1E-33 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 2.8E-78 T 14-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 4.3E-18 T 14-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 Gene3D G3DSA:3.40.50.300 1 212 3.4E-81 T 14-10-2018 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.876 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 SUPERFAMILY SSF52540 1 212 1.52E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10865 7a4d6f5da8dd491cb8b545d830d1161a 216 Pfam PF00406 Adenylate kinase 5 189 8.0E-60 T 14-10-2018 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 442 1.1E-189 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 SUPERFAMILY SSF52540 111 323 2.35E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 Pfam PF00308 Bacterial dnaA protein 111 327 3.0E-108 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 Pfam PF11638 DnaA N-terminal domain 6 66 2.6E-20 T 14-10-2018 IPR024633 DnaA N-terminal domain C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 358 424 5.2E-30 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 7.8E-54 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 7.8E-54 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 7.8E-54 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 7.8E-54 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 7.8E-54 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 35.187 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 SMART SM00760 355 424 1.9E-41 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 SMART SM00382 143 271 2.4E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 SUPERFAMILY SSF48295 342 445 2.51E-36 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 Gene3D G3DSA:3.30.300.180 1 82 2.8E-31 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 Gene3D G3DSA:3.40.50.300 95 275 1.1E-55 T 14-10-2018 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 Gene3D G3DSA:1.10.1750.10 346 445 5.1E-35 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 C2I25_11645 15a2be9192b61a95d8d355f9e1623895 446 Gene3D G3DSA:1.10.8.60 277 345 3.2E-30 T 14-10-2018 C2I25_14905 2ba08d51fafe6e3e2ba05d3b71f9fc92 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 1.8E-132 T 14-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 C2I25_14905 2ba08d51fafe6e3e2ba05d3b71f9fc92 272 Gene3D G3DSA:1.10.12.10 210 260 4.3E-29 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I25_14905 2ba08d51fafe6e3e2ba05d3b71f9fc92 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 267 3.0E-89 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I25_14905 2ba08d51fafe6e3e2ba05d3b71f9fc92 272 Gene3D G3DSA:3.90.226.10 1 209 4.4E-79 T 14-10-2018 C2I25_14905 2ba08d51fafe6e3e2ba05d3b71f9fc92 272 SUPERFAMILY SSF52096 7 267 1.12E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_14905 2ba08d51fafe6e3e2ba05d3b71f9fc92 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.781 T 14-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 C2I25_14905 2ba08d51fafe6e3e2ba05d3b71f9fc92 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I25_16615 3321f40e8fb8114a9dff3bb6d1f7413f 399 SUPERFAMILY SSF88697 6 74 1.19E-19 T 14-10-2018 IPR015947 PUA-like superfamily C2I25_16615 3321f40e8fb8114a9dff3bb6d1f7413f 399 Gene3D G3DSA:3.40.50.150 182 398 4.5E-55 T 14-10-2018 C2I25_16615 3321f40e8fb8114a9dff3bb6d1f7413f 399 SUPERFAMILY SSF53335 81 393 1.03E-64 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_16615 3321f40e8fb8114a9dff3bb6d1f7413f 399 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 112 381 4.9E-30 T 14-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 C2I25_16615 3321f40e8fb8114a9dff3bb6d1f7413f 399 SMART SM00359 5 90 8.4E-6 T 14-10-2018 IPR002478 PUA domain GO:0003723 C2I25_16615 3321f40e8fb8114a9dff3bb6d1f7413f 399 Gene3D G3DSA:2.30.130.10 5 73 1.2E-20 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 C2I25_16615 3321f40e8fb8114a9dff3bb6d1f7413f 399 Gene3D G3DSA:3.30.750.80 74 178 3.5E-38 T 14-10-2018 C2I25_13450 f073d31fbfc428d62a95c65a41084b58 293 Gene3D G3DSA:3.40.50.300 2 174 8.5E-6 T 14-10-2018 C2I25_13450 f073d31fbfc428d62a95c65a41084b58 293 PIRSF PIRSF005052 7 292 9.5E-110 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 C2I25_13450 f073d31fbfc428d62a95c65a41084b58 293 Pfam PF03668 P-loop ATPase protein family 7 290 1.1E-124 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 C2I25_13450 f073d31fbfc428d62a95c65a41084b58 293 SUPERFAMILY SSF52540 4 162 1.56E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13450 f073d31fbfc428d62a95c65a41084b58 293 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 7 289 42.61 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 C2I25_09820 93973d499b6ca44a85933eddc644deb7 185 SUPERFAMILY SSF52499 2 180 6.8E-54 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_09820 93973d499b6ca44a85933eddc644deb7 185 Pfam PF00857 Isochorismatase family 3 152 3.9E-35 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I25_09820 93973d499b6ca44a85933eddc644deb7 185 Gene3D G3DSA:3.40.50.850 1 184 4.8E-51 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I25_05240 dbdda45cf467e65185f2d6a1e530d7bd 132 Pfam PF02368 Bacterial Ig-like domain (group 2) 45 115 9.4E-5 T 14-10-2018 IPR003343 Bacterial Ig-like, group 2 C2I25_05240 dbdda45cf467e65185f2d6a1e530d7bd 132 Gene3D G3DSA:2.60.40.1080 38 125 1.2E-15 T 14-10-2018 C2I25_05240 dbdda45cf467e65185f2d6a1e530d7bd 132 SUPERFAMILY SSF49373 39 121 5.65E-9 T 14-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments C2I25_05045 785e1745c3d732915059d2f82cb5873d 251 Pfam PF08241 Methyltransferase domain 43 130 3.1E-14 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_05045 785e1745c3d732915059d2f82cb5873d 251 Gene3D G3DSA:3.40.50.150 5 236 3.6E-33 T 14-10-2018 C2I25_05045 785e1745c3d732915059d2f82cb5873d 251 SUPERFAMILY SSF53335 5 243 1.91E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_05365 351e904c78f0dc0fd499af49c75a1926 308 SUPERFAMILY SSF53448 8 252 3.98E-48 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_05365 351e904c78f0dc0fd499af49c75a1926 308 Pfam PF00535 Glycosyl transferase family 2 11 132 2.2E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_05365 351e904c78f0dc0fd499af49c75a1926 308 Gene3D G3DSA:3.90.550.10 1 269 6.1E-48 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_11830 aa0331a15b0e9a525422d4e6f93cb62c 605 Pfam PF01432 Peptidase family M3 212 589 1.4E-39 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 C2I25_11830 aa0331a15b0e9a525422d4e6f93cb62c 605 Gene3D G3DSA:1.10.1370.20 233 605 4.3E-118 T 14-10-2018 C2I25_11830 aa0331a15b0e9a525422d4e6f93cb62c 605 Gene3D G3DSA:1.20.140.70 28 183 2.7E-43 T 14-10-2018 C2I25_11830 aa0331a15b0e9a525422d4e6f93cb62c 605 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 11 601 9.8E-227 T 14-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 C2I25_11830 aa0331a15b0e9a525422d4e6f93cb62c 605 SUPERFAMILY SSF55486 11 584 4.4E-109 T 14-10-2018 C2I25_11830 aa0331a15b0e9a525422d4e6f93cb62c 605 Pfam PF08439 Oligopeptidase F 118 187 1.4E-21 T 14-10-2018 IPR013647 Oligopeptidase F, N-terminal domain C2I25_17385 15b6545c07f6ae01976887ddb4c51afa 584 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 573 5.8E-48 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_17385 15b6545c07f6ae01976887ddb4c51afa 584 SUPERFAMILY SSF56519 50 234 5.1E-18 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_17385 15b6545c07f6ae01976887ddb4c51afa 584 SUPERFAMILY SSF56601 188 581 2.0E-56 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_17385 15b6545c07f6ae01976887ddb4c51afa 584 Gene3D G3DSA:3.90.1310.30 50 234 1.7E-11 T 14-10-2018 C2I25_17385 15b6545c07f6ae01976887ddb4c51afa 584 Gene3D G3DSA:3.40.710.10 242 584 5.4E-65 T 14-10-2018 C2I25_23510 52a70f0b60cb39ead14df0e34c35b815 279 PIRSF PIRSF006483 1 278 6.7E-82 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_23510 52a70f0b60cb39ead14df0e34c35b815 279 Gene3D G3DSA:3.30.70.120 188 263 9.7E-23 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_23510 52a70f0b60cb39ead14df0e34c35b815 279 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 2.9E-60 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_23510 52a70f0b60cb39ead14df0e34c35b815 279 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 4.9E-22 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_05580 7b5ca80cd533690da3adb86316d0939b 65 Pfam PF12758 Protein of unknown function (DUF3813) 1 61 2.2E-28 T 14-10-2018 IPR024217 Protein of unknown function DUF3813 C2I25_10850 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 14-10-2018 C2I25_10850 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10850 7daf4c47f7f7eb87b15e0b26d32f1de9 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.2E-24 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10850 7daf4c47f7f7eb87b15e0b26d32f1de9 37 SUPERFAMILY SSF57840 1 37 6.41E-17 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10850 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Pfam PF00444 Ribosomal protein L36 1 37 5.7E-19 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10850 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.778 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_22370 649e6550fde91f425baaf6117a5c695d 183 Gene3D G3DSA:3.40.630.30 2 180 2.3E-39 T 14-10-2018 C2I25_22370 649e6550fde91f425baaf6117a5c695d 183 SUPERFAMILY SSF55729 1 175 9.01E-34 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_22370 649e6550fde91f425baaf6117a5c695d 183 Pfam PF13302 Acetyltransferase (GNAT) domain 13 150 8.6E-16 T 14-10-2018 IPR000182 GNAT domain C2I25_27970 b7bd8466e0d993f2a2012f2c4741f6ed 174 Gene3D G3DSA:3.40.630.30 8 173 1.6E-16 T 14-10-2018 C2I25_27970 b7bd8466e0d993f2a2012f2c4741f6ed 174 Pfam PF00583 Acetyltransferase (GNAT) family 42 145 1.3E-11 T 14-10-2018 IPR000182 GNAT domain C2I25_27970 b7bd8466e0d993f2a2012f2c4741f6ed 174 SUPERFAMILY SSF55729 15 170 5.15E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_02495 93177a5ce114c6198f3360cc0491268a 305 Gene3D G3DSA:3.40.50.1100 45 144 9.1E-118 T 14-10-2018 C2I25_02495 93177a5ce114c6198f3360cc0491268a 305 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 3.9E-126 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 C2I25_02495 93177a5ce114c6198f3360cc0491268a 305 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 1.4E-67 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_02495 93177a5ce114c6198f3360cc0491268a 305 SUPERFAMILY SSF53686 2 303 9.43E-99 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_02495 93177a5ce114c6198f3360cc0491268a 305 Gene3D G3DSA:3.40.50.1100 6 300 9.1E-118 T 14-10-2018 C2I25_02495 93177a5ce114c6198f3360cc0491268a 305 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 8.6E-134 T 14-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 C2I25_02495 93177a5ce114c6198f3360cc0491268a 305 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 C2I25_05200 38aee30f7e42dd20f1b135da3a588bfa 397 PIRSF PIRSF001413 1 397 1.4E-169 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I25_05200 38aee30f7e42dd20f1b135da3a588bfa 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 84 98 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I25_05200 38aee30f7e42dd20f1b135da3a588bfa 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 381 4.0E-45 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_05200 38aee30f7e42dd20f1b135da3a588bfa 397 Gene3D G3DSA:3.40.50.1100 13 209 1.2E-194 T 14-10-2018 C2I25_05200 38aee30f7e42dd20f1b135da3a588bfa 397 SUPERFAMILY SSF53686 6 392 1.13E-148 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_05200 38aee30f7e42dd20f1b135da3a588bfa 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 10 393 2.8E-197 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I25_05200 38aee30f7e42dd20f1b135da3a588bfa 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 5 394 54.224 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I25_05200 38aee30f7e42dd20f1b135da3a588bfa 397 Gene3D G3DSA:3.40.50.1100 57 387 1.2E-194 T 14-10-2018 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 2.7E-32 T 14-10-2018 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 449 464 2.7E-32 T 14-10-2018 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 481 2.7E-32 T 14-10-2018 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 502 514 2.7E-32 T 14-10-2018 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 449 467 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:3.50.30.10 7 234 4.9E-82 T 14-10-2018 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF47831 25 144 1.12E-37 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 PIRSF PIRSF000732 1 570 1.8E-226 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF52009 126 247 3.66E-38 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 568 1.7E-255 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 226 9.6E-24 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 127 8.5E-34 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF51621 251 551 1.73E-111 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:3.20.20.60 235 570 2.7E-126 T 14-10-2018 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 542 4.1E-126 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 C2I25_19230 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:1.10.274.10 24 147 4.9E-82 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 C2I25_12800 8cedd747ad90f564111ed6e950e7622e 247 Pfam PF02706 Chain length determinant protein 3 93 2.0E-20 T 14-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 C2I25_12800 8cedd747ad90f564111ed6e950e7622e 247 Pfam PF13807 G-rich domain on putative tyrosine kinase 143 194 2.0E-8 T 14-10-2018 IPR032807 Tyrosine kinase, G-rich domain C2I25_12395 7d835e6845a54ef0a6ba8299b7ebab78 244 PIRSF PIRSF006648 1 243 1.4E-22 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 C2I25_12395 7d835e6845a54ef0a6ba8299b7ebab78 244 Pfam PF12698 ABC-2 family transporter protein 50 236 5.3E-17 T 14-10-2018 C2I25_18955 794a4eb030f31fa97e0e88153c0413b2 79 Pfam PF13025 Protein of unknown function (DUF3886) 11 77 6.5E-22 T 14-10-2018 IPR024980 Protein of unknown function DUF3886 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 SUPERFAMILY SSF69075 317 420 3.66E-16 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 SUPERFAMILY SSF69742 2 158 8.89E-45 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 Gene3D G3DSA:3.40.50.720 161 312 2.3E-43 T 14-10-2018 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 420 28.949 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 2.7E-145 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.2E-44 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 321 419 6.3E-19 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 Gene3D G3DSA:3.30.460.30 1 158 4.0E-52 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 PIRSF PIRSF000445 1 434 6.3E-149 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 3.6E-44 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 SUPERFAMILY SSF51735 163 314 1.08E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_16950 e13f6cd461e2a02e0321d4c0c7721863 444 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 14-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I25_14950 e5d495770b3894f6dd00e302a5783621 338 Gene3D G3DSA:3.40.1190.20 2 338 7.1E-102 T 14-10-2018 IPR029056 Ribokinase-like C2I25_14950 e5d495770b3894f6dd00e302a5783621 338 SUPERFAMILY SSF53613 1 328 1.71E-63 T 14-10-2018 IPR029056 Ribokinase-like C2I25_14950 e5d495770b3894f6dd00e302a5783621 338 Pfam PF00294 pfkB family carbohydrate kinase 3 317 1.6E-33 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB C2I25_21155 8c0a80996e723d67eba0cfe65d661fe6 306 Pfam PF00005 ABC transporter 27 167 1.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21155 8c0a80996e723d67eba0cfe65d661fe6 306 Gene3D G3DSA:3.40.50.300 2 250 1.9E-64 T 14-10-2018 C2I25_21155 8c0a80996e723d67eba0cfe65d661fe6 306 SUPERFAMILY SSF52540 8 224 1.81E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21155 8c0a80996e723d67eba0cfe65d661fe6 306 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_21155 8c0a80996e723d67eba0cfe65d661fe6 306 SMART SM00382 35 216 1.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 Gene3D G3DSA:3.65.10.10 23 231 4.3E-157 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 428 1.3E-134 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 Gene3D G3DSA:3.65.10.10 13 424 4.3E-157 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 429 33.641 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 424 3.6E-128 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 SUPERFAMILY SSF55205 11 427 1.64E-137 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I25_24820 e31cdd1a5884c87dd2c35b93c06c7a7a 429 PIRSF PIRSF000505 1 429 1.8E-119 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I25_23685 6c299dc0c15f6bdbb52630aa15c04a06 445 SUPERFAMILY SSF159501 36 444 7.59E-112 T 14-10-2018 C2I25_23685 6c299dc0c15f6bdbb52630aa15c04a06 445 Gene3D G3DSA:3.40.1660.10 45 441 3.5E-142 T 14-10-2018 C2I25_23685 6c299dc0c15f6bdbb52630aa15c04a06 445 Pfam PF05139 Erythromycin esterase 101 439 1.8E-65 T 14-10-2018 IPR007815 Erythromycin esterase GO:0046677 C2I25_23685 6c299dc0c15f6bdbb52630aa15c04a06 445 Gene3D G3DSA:1.20.1440.30 175 301 3.5E-142 T 14-10-2018 C2I25_23685 6c299dc0c15f6bdbb52630aa15c04a06 445 Gene3D G3DSA:3.30.1870.10 103 174 3.5E-142 T 14-10-2018 C2I25_23685 6c299dc0c15f6bdbb52630aa15c04a06 445 PIRSF PIRSF036794 23 445 3.1E-154 T 14-10-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type C2I25_04755 eb85e3ee1050f7c030011099941e8c18 207 Pfam PF00571 CBS domain 12 59 2.4E-6 T 14-10-2018 IPR000644 CBS domain C2I25_04755 eb85e3ee1050f7c030011099941e8c18 207 Gene3D G3DSA:3.10.580.10 1 127 1.0E-18 T 14-10-2018 C2I25_04755 eb85e3ee1050f7c030011099941e8c18 207 SUPERFAMILY SSF54631 2 124 1.64E-21 T 14-10-2018 C2I25_04755 eb85e3ee1050f7c030011099941e8c18 207 PIRSF PIRSF035040 1 207 7.8E-89 T 14-10-2018 IPR017036 Uncharacterised conserved protein UCP035040, CBS-type C2I25_14665 98d34fddbcec1eaf85007918e386c6c1 331 Gene3D G3DSA:1.10.287.70 2 96 1.8E-20 T 14-10-2018 C2I25_14665 98d34fddbcec1eaf85007918e386c6c1 331 Pfam PF02254 TrkA-N domain 118 238 3.3E-13 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I25_14665 98d34fddbcec1eaf85007918e386c6c1 331 Pfam PF07885 Ion channel 23 97 9.2E-14 T 14-10-2018 IPR013099 Potassium channel domain C2I25_14665 98d34fddbcec1eaf85007918e386c6c1 331 SUPERFAMILY SSF116726 296 329 7.59E-5 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_14665 98d34fddbcec1eaf85007918e386c6c1 331 SUPERFAMILY SSF51735 115 251 7.19E-17 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_14665 98d34fddbcec1eaf85007918e386c6c1 331 SUPERFAMILY SSF81324 14 135 2.35E-24 T 14-10-2018 C2I25_14665 98d34fddbcec1eaf85007918e386c6c1 331 Gene3D G3DSA:3.40.50.720 97 238 4.2E-24 T 14-10-2018 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 Gene3D G3DSA:3.90.226.10 1 315 1.8E-123 T 14-10-2018 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 4 146 6.1E-66 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 132 148 7.3E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 167 180 7.3E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 86 97 7.3E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 195 204 7.3E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 151 164 7.3E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 111 129 7.3E-47 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 3 314 49.829 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 SUPERFAMILY SSF52096 5 313 7.68E-104 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_16295 ff244e8749cb23f735c6f776aa08952f 324 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 316 9.7E-159 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 SUPERFAMILY SSF56420 1 148 3.93E-54 T 14-10-2018 IPR036821 Peptide deformylase superfamily C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 Hamap MF_00163 Peptide deformylase [def]. 2 155 27.809 T 14-10-2018 IPR023635 Peptide deformylase C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 Pfam PF01327 Polypeptide deformylase 4 148 8.3E-47 T 14-10-2018 IPR023635 Peptide deformylase C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 PIRSF PIRSF004749 1 155 1.5E-47 T 14-10-2018 IPR023635 Peptide deformylase C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 PRINTS PR01576 Peptide deformylase signature 119 148 3.4E-35 T 14-10-2018 IPR023635 Peptide deformylase C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 PRINTS PR01576 Peptide deformylase signature 100 118 3.4E-35 T 14-10-2018 IPR023635 Peptide deformylase C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 PRINTS PR01576 Peptide deformylase signature 88 99 3.4E-35 T 14-10-2018 IPR023635 Peptide deformylase C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 PRINTS PR01576 Peptide deformylase signature 33 62 3.4E-35 T 14-10-2018 IPR023635 Peptide deformylase C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 Gene3D G3DSA:3.90.45.10 1 156 8.7E-63 T 14-10-2018 IPR036821 Peptide deformylase superfamily C2I25_20170 6b5dac54a02dac618033c9b41404c850 156 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 153 7.7E-53 T 14-10-2018 IPR023635 Peptide deformylase C2I25_26145 1eb993e24b6c94f36d822769feb89727 147 SUPERFAMILY SSF55811 5 125 5.96E-25 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_26145 1eb993e24b6c94f36d822769feb89727 147 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_26145 1eb993e24b6c94f36d822769feb89727 147 Pfam PF00293 NUDIX domain 7 114 3.3E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_26145 1eb993e24b6c94f36d822769feb89727 147 PRINTS PR00502 NUDIX hydrolase family signature 46 61 9.8E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_26145 1eb993e24b6c94f36d822769feb89727 147 PRINTS PR00502 NUDIX hydrolase family signature 32 46 9.8E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_26145 1eb993e24b6c94f36d822769feb89727 147 Gene3D G3DSA:3.90.79.10 1 139 5.3E-27 T 14-10-2018 C2I25_12890 fd3c72eb8c463d49c3384add38324085 260 Pfam PF13057 Protein of unknown function (DUF3919) 37 253 3.2E-43 T 14-10-2018 IPR025031 Protein of unknown function DUF3919 C2I25_20050 29a3525441906b5a219019018c7a4956 304 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 289 3.4E-99 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20050 29a3525441906b5a219019018c7a4956 304 Gene3D G3DSA:3.40.50.1370 6 287 7.3E-103 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 Gene3D G3DSA:3.40.50.1370 127 270 7.3E-103 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 SUPERFAMILY SSF53671 1 292 4.98E-92 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 139 1.3E-41 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 2.2E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 2.2E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 2.2E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 272 286 2.2E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 2.2E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 248 253 2.2E-32 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20050 29a3525441906b5a219019018c7a4956 304 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 293 40.465 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20050 29a3525441906b5a219019018c7a4956 304 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 9.0E-23 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 9.0E-23 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 279 9.0E-23 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 244 253 9.0E-23 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_20050 29a3525441906b5a219019018c7a4956 304 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 287 4.8E-21 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 C2I25_23270 55d81178298dfbefe9f179c20af28322 278 Gene3D G3DSA:3.10.20.490 178 276 4.4E-12 T 14-10-2018 C2I25_23270 55d81178298dfbefe9f179c20af28322 278 Pfam PF14478 Domain of unknown function (DUF4430) 205 275 2.8E-15 T 14-10-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 C2I25_12535 53f437942e8576e2b69d91092ad39890 290 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 40 165 2.9E-47 T 14-10-2018 IPR014202 Sporulation stage II, protein R C2I25_12535 53f437942e8576e2b69d91092ad39890 290 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 6 171 2.9E-60 T 14-10-2018 IPR014202 Sporulation stage II, protein R C2I25_14150 0588c09980c3f893c2951ed36ae8637b 114 SUPERFAMILY SSF110455 1 111 5.75E-33 T 14-10-2018 C2I25_14150 0588c09980c3f893c2951ed36ae8637b 114 Gene3D G3DSA:3.40.1360.20 1 114 6.2E-42 T 14-10-2018 C2I25_14150 0588c09980c3f893c2951ed36ae8637b 114 SMART SM00493 5 79 1.8E-5 T 14-10-2018 IPR006171 TOPRIM domain C2I25_12105 ecc098d61ad03afa09bef1326ddc0053 274 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 261 8.8E-88 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I25_12105 ecc098d61ad03afa09bef1326ddc0053 274 Gene3D G3DSA:3.40.1190.20 1 269 1.1E-90 T 14-10-2018 IPR029056 Ribokinase-like C2I25_12105 ecc098d61ad03afa09bef1326ddc0053 274 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 3.2E-92 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 C2I25_12105 ecc098d61ad03afa09bef1326ddc0053 274 SUPERFAMILY SSF53613 4 265 1.51E-78 T 14-10-2018 IPR029056 Ribokinase-like C2I25_03095 57b3453fa0a1f81377b1a755714c88bc 111 Pfam PF13107 Protein of unknown function (DUF3964) 2 108 4.5E-58 T 14-10-2018 IPR025082 Protein of unknown function DUF3964 C2I25_10465 1705dd87ea09cc41cfb267a73184fb7a 201 Pfam PF01553 Acyltransferase 18 141 3.8E-26 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I25_10465 1705dd87ea09cc41cfb267a73184fb7a 201 SUPERFAMILY SSF69593 16 196 4.71E-39 T 14-10-2018 C2I25_10465 1705dd87ea09cc41cfb267a73184fb7a 201 SMART SM00563 33 144 1.1E-27 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I25_16755 8c2960c44be539c925fe0ada1d46f79c 259 SUPERFAMILY SSF55166 93 246 5.23E-40 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_16755 8c2960c44be539c925fe0ada1d46f79c 259 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 110 237 9.3E-48 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 C2I25_16755 8c2960c44be539c925fe0ada1d46f79c 259 Gene3D G3DSA:3.30.1380.10 50 259 6.5E-78 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_06395 a1a1357ab5124b6ea5ead0cd9e0dec10 176 Pfam PF11181 Heat induced stress protein YflT 8 60 1.6E-7 T 14-10-2018 IPR025889 General stress protein 17M-like domain C2I25_26775 71b30ebd4992e2d291c9b446b4a31db5 229 Gene3D G3DSA:1.20.910.10 1 220 5.8E-67 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 C2I25_26775 71b30ebd4992e2d291c9b446b4a31db5 229 Pfam PF03070 TENA/THI-4/PQQC family 9 214 1.2E-57 T 14-10-2018 IPR004305 Thiaminase-2/PQQC C2I25_26775 71b30ebd4992e2d291c9b446b4a31db5 229 SUPERFAMILY SSF48613 3 221 6.53E-74 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 C2I25_26775 71b30ebd4992e2d291c9b446b4a31db5 229 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 214 3.3E-75 T 14-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 C2I25_23735 ad358c3ad4b2ce5ea62c3fef483b0f46 116 Pfam PF13564 DoxX-like family 9 109 1.5E-14 T 14-10-2018 IPR032808 DoxX family C2I25_15855 a90085d19586616f47d0e2ce57d90a58 371 Gene3D G3DSA:3.40.1830.10 2 165 8.7E-14 T 14-10-2018 IPR035097 Peptidase M29, N-terminal C2I25_15855 a90085d19586616f47d0e2ce57d90a58 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 338 3.6E-60 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_15855 a90085d19586616f47d0e2ce57d90a58 371 SUPERFAMILY SSF144052 1 360 3.53E-112 T 14-10-2018 C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 Gene3D G3DSA:3.50.50.60 34 379 2.8E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 Pfam PF00355 Rieske [2Fe-2S] domain 423 504 8.2E-14 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 SUPERFAMILY SSF50022 423 505 1.7E-24 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 Gene3D G3DSA:2.102.10.10 406 508 1.5E-25 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 Gene3D G3DSA:3.30.9.10 126 337 2.8E-45 T 14-10-2018 C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 Pfam PF01266 FAD dependent oxidoreductase 33 376 5.1E-43 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 SUPERFAMILY SSF51905 30 385 9.06E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 490 502 5.1E-8 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 457 468 5.1E-8 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I25_09525 4d77e7b654766d2617cb05f737088fab 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 478 490 5.1E-8 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I25_04945 98ef82ce1b1ca8588bc4e6dd00b9f8f7 275 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 152 273 3.7E-62 T 14-10-2018 IPR014258 CAP domain, YkwD-like C2I25_04945 98ef82ce1b1ca8588bc4e6dd00b9f8f7 275 Pfam PF00188 Cysteine-rich secretory protein family 160 272 1.4E-24 T 14-10-2018 IPR014044 CAP domain C2I25_04945 98ef82ce1b1ca8588bc4e6dd00b9f8f7 275 Gene3D G3DSA:3.40.33.10 13 274 6.6E-67 T 14-10-2018 IPR035940 CAP superfamily C2I25_04945 98ef82ce1b1ca8588bc4e6dd00b9f8f7 275 SUPERFAMILY SSF55797 151 272 2.88E-28 T 14-10-2018 IPR035940 CAP superfamily C2I25_06100 91f7162b3eef27156dd07e887bab0f16 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 3.8E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06100 91f7162b3eef27156dd07e887bab0f16 178 SUPERFAMILY SSF46689 4 70 1.74E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_06100 91f7162b3eef27156dd07e887bab0f16 178 SUPERFAMILY SSF48498 102 173 1.27E-14 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_06100 91f7162b3eef27156dd07e887bab0f16 178 Gene3D G3DSA:1.10.357.10 4 177 1.6E-50 T 14-10-2018 C2I25_06100 91f7162b3eef27156dd07e887bab0f16 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06100 91f7162b3eef27156dd07e887bab0f16 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_24430 196165d8e376560f771928fd75300659 97 Gene3D G3DSA:3.30.70.100 1 95 2.1E-25 T 14-10-2018 C2I25_24430 196165d8e376560f771928fd75300659 97 SUPERFAMILY SSF54909 1 92 2.72E-25 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_24430 196165d8e376560f771928fd75300659 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 1.2E-18 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I25_00215 1e5c1ef2b4c18b45061f32e8b6ac64bd 195 Gene3D G3DSA:3.40.30.10 27 195 1.0E-56 T 14-10-2018 C2I25_00215 1e5c1ef2b4c18b45061f32e8b6ac64bd 195 SUPERFAMILY SSF52833 37 195 1.41E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_00215 1e5c1ef2b4c18b45061f32e8b6ac64bd 195 Pfam PF02630 SCO1/SenC 25 176 5.9E-39 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_11935 deea55d731febe6b3126cef37b74277c 196 Gene3D G3DSA:1.25.40.600 1 167 4.0E-39 T 14-10-2018 IPR038523 AmiS/UreI transporter superfamily C2I25_11935 deea55d731febe6b3126cef37b74277c 196 Pfam PF02293 AmiS/UreI family transporter 1 164 2.1E-49 T 14-10-2018 IPR003211 AmiS/UreI transporter GO:0016020 C2I25_05990 2311ac2c201aca233f328b7c5558a34c 101 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 22 87 1.0E-22 T 14-10-2018 IPR018656 Domain of unknown function DUF2087 C2I25_17780 0d00963e60a200c2c9a6c320310d82be 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 1.4E-46 T 14-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 C2I25_17780 0d00963e60a200c2c9a6c320310d82be 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 98 2.8E-16 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I25_17780 0d00963e60a200c2c9a6c320310d82be 132 SUPERFAMILY SSF53927 3 130 2.06E-48 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I25_17780 0d00963e60a200c2c9a6c320310d82be 132 Gene3D G3DSA:3.40.140.10 1 132 3.9E-61 T 14-10-2018 C2I25_17780 0d00963e60a200c2c9a6c320310d82be 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.3E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 SUPERFAMILY SSF48008 95 231 1.52E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 Gene3D G3DSA:1.10.10.10 1 74 6.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 Pfam PF07729 FCD domain 100 225 1.5E-23 T 14-10-2018 IPR011711 GntR, C-terminal C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 SUPERFAMILY SSF46785 6 78 3.39E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 SMART SM00345 15 74 2.5E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 SMART SM00895 99 226 1.3E-22 T 14-10-2018 IPR011711 GntR, C-terminal C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 Gene3D G3DSA:1.20.120.530 80 235 8.2E-32 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_04910 e95925f7b2132fa825e18ccd62aa23f0 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I25_10995 0e338df27b45808f9deabb4d3aa57024 156 SUPERFAMILY SSF47973 1 149 9.42E-61 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily C2I25_10995 0e338df27b45808f9deabb4d3aa57024 156 PIRSF PIRSF002122 5 156 1.5E-59 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 C2I25_10995 0e338df27b45808f9deabb4d3aa57024 156 Gene3D G3DSA:1.10.455.10 2 156 1.5E-63 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily C2I25_10995 0e338df27b45808f9deabb4d3aa57024 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 6.4E-70 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 C2I25_10995 0e338df27b45808f9deabb4d3aa57024 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10995 0e338df27b45808f9deabb4d3aa57024 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 7.1E-66 T 14-10-2018 IPR023798 Ribosomal protein S7 domain C2I25_10995 0e338df27b45808f9deabb4d3aa57024 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.574 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 C2I25_10015 5959cb9dd44bb6680652f98a3e221ce4 358 Gene3D G3DSA:3.20.20.80 1 355 1.2E-11 T 14-10-2018 C2I25_10015 5959cb9dd44bb6680652f98a3e221ce4 358 Pfam PF14307 Glycosyltransferase WbsX 3 339 6.5E-137 T 14-10-2018 IPR032719 Glycosyltransferase WbsX C2I25_24325 de717da0b5063038665b075af92a8ccc 247 PIRSF PIRSF000883 2 243 4.9E-56 T 14-10-2018 IPR011152 Phosphoesterase MJ0912 C2I25_24325 de717da0b5063038665b075af92a8ccc 247 SUPERFAMILY SSF56300 1 232 1.67E-51 T 14-10-2018 C2I25_24325 de717da0b5063038665b075af92a8ccc 247 Gene3D G3DSA:3.60.21.10 1 245 6.9E-63 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_24325 de717da0b5063038665b075af92a8ccc 247 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 192 8.0E-24 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 C2I25_12260 432554064e1120368c82987504362b24 338 Gene3D G3DSA:1.10.3470.10 7 338 4.9E-101 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_12260 432554064e1120368c82987504362b24 338 SUPERFAMILY SSF81345 7 336 1.06E-86 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_12260 432554064e1120368c82987504362b24 338 Pfam PF01032 FecCD transport family 21 336 7.8E-96 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_01805 683ed83afe0928b7d0236cc62854ca1e 290 SUPERFAMILY SSF81301 1 133 2.37E-49 T 14-10-2018 C2I25_01805 683ed83afe0928b7d0236cc62854ca1e 290 Pfam PF04439 Streptomycin adenylyltransferase 1 279 3.4E-128 T 14-10-2018 IPR007530 Aminoglycoside 6-adenylyltransferase C2I25_01805 683ed83afe0928b7d0236cc62854ca1e 290 PIRSF PIRSF000812 1 285 6.5E-125 T 14-10-2018 IPR007530 Aminoglycoside 6-adenylyltransferase C2I25_01805 683ed83afe0928b7d0236cc62854ca1e 290 Gene3D G3DSA:1.20.120.330 149 288 6.1E-49 T 14-10-2018 C2I25_01805 683ed83afe0928b7d0236cc62854ca1e 290 Gene3D G3DSA:3.30.460.10 9 148 1.9E-56 T 14-10-2018 C2I25_01805 683ed83afe0928b7d0236cc62854ca1e 290 SUPERFAMILY SSF81631 137 280 8.63E-57 T 14-10-2018 C2I25_26810 bb9f29b488cf73ff42742c6511b1fc0e 643 PIRSF PIRSF018968 1 641 2.3E-129 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_26810 bb9f29b488cf73ff42742c6511b1fc0e 643 Pfam PF02687 FtsX-like permease family 90 181 9.6E-9 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_05840 4952fedcf4c36a0276770f5af026e0f9 459 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 427 3.5E-72 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_05840 4952fedcf4c36a0276770f5af026e0f9 459 Pfam PF07690 Major Facilitator Superfamily 25 416 2.8E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_05840 4952fedcf4c36a0276770f5af026e0f9 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 84 106 1.6E-7 T 14-10-2018 C2I25_05840 4952fedcf4c36a0276770f5af026e0f9 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 1.6E-7 T 14-10-2018 C2I25_05840 4952fedcf4c36a0276770f5af026e0f9 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 407 426 1.6E-7 T 14-10-2018 C2I25_05840 4952fedcf4c36a0276770f5af026e0f9 459 SUPERFAMILY SSF103473 21 457 2.18E-55 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_05840 4952fedcf4c36a0276770f5af026e0f9 459 Gene3D G3DSA:1.20.1250.20 261 459 1.1E-16 T 14-10-2018 C2I25_05840 4952fedcf4c36a0276770f5af026e0f9 459 Gene3D G3DSA:1.20.1720.10 20 228 1.1E-42 T 14-10-2018 C2I25_08110 2328da34caa1500c60596af2b46a4a7a 333 TIGRFAM TIGR03395 sphingomy: sphingomyelin phosphodiesterase 37 330 6.1E-144 T 14-10-2018 IPR017766 Sphingomyelinase C/phospholipase C GO:0005576|GO:0008081 C2I25_08110 2328da34caa1500c60596af2b46a4a7a 333 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 61 289 2.2E-15 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase C2I25_08110 2328da34caa1500c60596af2b46a4a7a 333 SUPERFAMILY SSF56219 34 330 1.31E-79 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_08110 2328da34caa1500c60596af2b46a4a7a 333 Gene3D G3DSA:3.60.10.10 28 333 1.1E-101 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_02545 47f7e50617bec0109eeee46197a821ce 541 Pfam PF14158 YndJ-like protein 28 279 5.0E-86 T 14-10-2018 IPR025450 YndJ-like protein C2I25_17555 603b92ecab9e1056363cca21aa24443f 216 Gene3D G3DSA:3.30.460.10 1 155 1.2E-49 T 14-10-2018 C2I25_17555 603b92ecab9e1056363cca21aa24443f 216 Pfam PF04607 Region found in RelA / SpoT proteins 50 171 1.5E-38 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I25_17555 603b92ecab9e1056363cca21aa24443f 216 Gene3D G3DSA:1.10.287.860 156 208 6.4E-22 T 14-10-2018 C2I25_17555 603b92ecab9e1056363cca21aa24443f 216 SMART SM00954 50 173 2.2E-46 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I25_17555 603b92ecab9e1056363cca21aa24443f 216 SUPERFAMILY SSF81301 11 202 1.32E-56 T 14-10-2018 C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.3E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 SUPERFAMILY SSF51735 2 250 6.96E-86 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.0E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.0E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.0E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 Gene3D G3DSA:3.40.50.720 1 254 1.5E-86 T 14-10-2018 C2I25_19530 b266182c7dee07cfae6178251cb73b63 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 5.6E-62 T 14-10-2018 C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 Pfam PF00561 alpha/beta hydrolase fold 25 132 4.2E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 SUPERFAMILY SSF53474 9 259 1.71E-56 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 PRINTS PR00412 Epoxide hydrolase signature 236 258 3.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 PRINTS PR00412 Epoxide hydrolase signature 50 65 3.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 PRINTS PR00412 Epoxide hydrolase signature 30 48 3.2E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 1.9E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 219 1.9E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.9E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_27265 09e72051cf6a702fb834d4feb76e44df 260 Gene3D G3DSA:3.40.50.1820 4 260 4.2E-59 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_19020 50a3d270caf0873da4e4a76572223c45 273 PIRSF PIRSF000477 1 271 5.4E-123 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 C2I25_19020 50a3d270caf0873da4e4a76572223c45 273 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 268 7.8E-121 T 14-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 C2I25_19020 50a3d270caf0873da4e4a76572223c45 273 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 75 116 - T 14-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 C2I25_19020 50a3d270caf0873da4e4a76572223c45 273 SUPERFAMILY SSF53167 4 271 2.49E-102 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I25_19020 50a3d270caf0873da4e4a76572223c45 273 Pfam PF01048 Phosphorylase superfamily 23 268 3.1E-60 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I25_19020 50a3d270caf0873da4e4a76572223c45 273 Gene3D G3DSA:3.40.50.1580 1 272 3.1E-119 T 14-10-2018 C2I25_19020 50a3d270caf0873da4e4a76572223c45 273 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 269 7.9E-113 T 14-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 C2I25_05410 6a642813575bd2471f67bbe6744ac1bc 132 SUPERFAMILY SSF46458 7 124 6.3E-40 T 14-10-2018 IPR009050 Globin-like superfamily C2I25_05410 6a642813575bd2471f67bbe6744ac1bc 132 Pfam PF01152 Bacterial-like globin 9 123 8.2E-34 T 14-10-2018 IPR001486 Truncated hemoglobin GO:0019825 C2I25_05410 6a642813575bd2471f67bbe6744ac1bc 132 Gene3D G3DSA:1.10.490.10 1 131 8.9E-50 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 C2I25_05410 6a642813575bd2471f67bbe6744ac1bc 132 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 53 77 - T 14-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 C2I25_19660 659089724af875a17ad9455d65bbda27 98 Pfam PF11256 Protein of unknown function (DUF3055) 5 84 1.1E-34 T 14-10-2018 IPR021415 Protein of unknown function DUF3055 C2I25_17495 20e4a966890b1fe8ca67a058e648694d 584 SUPERFAMILY SSF56534 10 332 6.15E-83 T 14-10-2018 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily C2I25_17495 20e4a966890b1fe8ca67a058e648694d 584 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 22 146 8.2E-11 T 14-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 C2I25_17495 20e4a966890b1fe8ca67a058e648694d 584 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 201 290 2.7E-19 T 14-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 C2I25_19200 54d1a02d69cf6b93353488b251c8a413 262 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 220 3.6E-21 T 14-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 C2I25_19200 54d1a02d69cf6b93353488b251c8a413 262 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 113 131 - T 14-10-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 C2I25_19200 54d1a02d69cf6b93353488b251c8a413 262 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 234 40.06 T 14-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 C2I25_19200 54d1a02d69cf6b93353488b251c8a413 262 Gene3D G3DSA:3.40.50.1360 1 232 3.3E-97 T 14-10-2018 C2I25_19200 54d1a02d69cf6b93353488b251c8a413 262 SUPERFAMILY SSF100950 1 232 1.41E-85 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_19200 54d1a02d69cf6b93353488b251c8a413 262 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 232 2.0E-72 T 14-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 C2I25_25065 b71704cd94932fc43a842417a257776a 169 Pfam PF13563 2'-5' RNA ligase superfamily 15 151 2.6E-16 T 14-10-2018 C2I25_25065 b71704cd94932fc43a842417a257776a 169 Gene3D G3DSA:3.90.1140.10 3 166 6.7E-25 T 14-10-2018 C2I25_25065 b71704cd94932fc43a842417a257776a 169 SUPERFAMILY SSF55144 20 162 2.04E-14 T 14-10-2018 IPR009097 Cyclic phosphodiesterase C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 SUPERFAMILY SSF53850 99 292 8.33E-27 T 14-10-2018 C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 Gene3D G3DSA:3.40.190.290 91 290 5.6E-63 T 14-10-2018 C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 SUPERFAMILY SSF46785 8 120 8.84E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 Gene3D G3DSA:1.10.10.10 4 90 4.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 2.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 2.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 2.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 Pfam PF03466 LysR substrate binding domain 97 289 2.6E-31 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_19575 e92db2d13c815c0f46b560dd292e7f06 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 1.2E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_19835 d89a3646407c2398f79168e5a1ca6d89 88 Hamap MF_01126 UPF0298 protein . 1 78 23.278 T 14-10-2018 IPR016979 Protein of unknown function DUF2129 C2I25_19835 d89a3646407c2398f79168e5a1ca6d89 88 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 8.0E-30 T 14-10-2018 IPR016979 Protein of unknown function DUF2129 C2I25_19835 d89a3646407c2398f79168e5a1ca6d89 88 PIRSF PIRSF031653 1 88 1.8E-34 T 14-10-2018 IPR016979 Protein of unknown function DUF2129 C2I25_00745 beed5cf77e9879c8857a27e03d2ad5d9 468 SUPERFAMILY SSF52540 26 205 3.87E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_00745 beed5cf77e9879c8857a27e03d2ad5d9 468 Gene3D G3DSA:3.40.50.300 6 200 1.2E-24 T 14-10-2018 C2I25_00745 beed5cf77e9879c8857a27e03d2ad5d9 468 Gene3D G3DSA:3.30.420.240 253 457 1.8E-14 T 14-10-2018 C2I25_05440 c749eca42eac5e0cddb5d8d5916b3d70 227 PIRSF PIRSF029008 1 225 6.0E-78 T 14-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I25_05440 c749eca42eac5e0cddb5d8d5916b3d70 227 Gene3D G3DSA:3.30.70.1950 126 225 2.6E-30 T 14-10-2018 IPR038471 MecA, C-terminal domain superfamily C2I25_05440 c749eca42eac5e0cddb5d8d5916b3d70 227 Pfam PF05389 Negative regulator of genetic competence (MecA) 2 219 2.3E-48 T 14-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I25_05440 c749eca42eac5e0cddb5d8d5916b3d70 227 Hamap MF_01124 Adapter protein MecA [mecA]. 1 223 27.465 T 14-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I25_26090 7e63a25dbf7ec629ca8e4282699f6db7 123 Pfam PF14176 YxiJ-like protein 10 118 4.3E-51 T 14-10-2018 IPR025551 Immunity protein WapI-like C2I25_27065 cdeee5c26bacdda30942ed34c5e404da 338 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 266 1.1E-55 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_27065 cdeee5c26bacdda30942ed34c5e404da 338 SUPERFAMILY SSF56601 4 284 1.34E-52 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_27065 cdeee5c26bacdda30942ed34c5e404da 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 114 131 3.7E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_27065 cdeee5c26bacdda30942ed34c5e404da 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 61 72 3.7E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_27065 cdeee5c26bacdda30942ed34c5e404da 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 154 3.7E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_27065 cdeee5c26bacdda30942ed34c5e404da 338 Gene3D G3DSA:3.40.710.10 27 285 2.3E-66 T 14-10-2018 C2I25_13605 8190d134e4f14b585937cd5c7d6224c7 225 Pfam PF00072 Response regulator receiver domain 4 113 5.1E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_13605 8190d134e4f14b585937cd5c7d6224c7 225 Gene3D G3DSA:1.10.10.10 123 224 1.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_13605 8190d134e4f14b585937cd5c7d6224c7 225 SUPERFAMILY SSF52172 3 127 3.84E-27 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_13605 8190d134e4f14b585937cd5c7d6224c7 225 SMART SM00862 148 223 1.5E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_13605 8190d134e4f14b585937cd5c7d6224c7 225 SUPERFAMILY SSF46894 128 223 2.01E-27 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_13605 8190d134e4f14b585937cd5c7d6224c7 225 Gene3D G3DSA:3.40.50.2300 1 122 1.0E-28 T 14-10-2018 C2I25_13605 8190d134e4f14b585937cd5c7d6224c7 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 2.5E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_13605 8190d134e4f14b585937cd5c7d6224c7 225 SMART SM00448 2 112 9.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_20805 1cfbb41e39e2112132da41a676029059 209 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 39 204 4.5E-7 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_17105 2a48fdcb0128d311ac4ba58faead608a 283 Gene3D G3DSA:3.40.190.10 6 181 7.6E-56 T 14-10-2018 C2I25_17105 2a48fdcb0128d311ac4ba58faead608a 283 Gene3D G3DSA:3.30.70.260 193 282 7.4E-24 T 14-10-2018 C2I25_17105 2a48fdcb0128d311ac4ba58faead608a 283 PIRSF PIRSF001500 1 282 2.8E-67 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 C2I25_17105 2a48fdcb0128d311ac4ba58faead608a 283 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 228 235 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 C2I25_17105 2a48fdcb0128d311ac4ba58faead608a 283 SUPERFAMILY SSF55021 178 279 7.91E-23 T 14-10-2018 C2I25_17105 2a48fdcb0128d311ac4ba58faead608a 283 SUPERFAMILY SSF53850 3 187 2.71E-53 T 14-10-2018 C2I25_17105 2a48fdcb0128d311ac4ba58faead608a 283 Gene3D G3DSA:3.40.190.10 84 173 7.6E-56 T 14-10-2018 C2I25_17105 2a48fdcb0128d311ac4ba58faead608a 283 Pfam PF00800 Prephenate dehydratase 4 185 1.5E-59 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 C2I25_14600 e9a87a44349ff2fc6772e8b4352641d9 127 SUPERFAMILY SSF141251 4 126 5.62E-53 T 14-10-2018 IPR038080 Kinase associated protein B superfamily C2I25_14600 e9a87a44349ff2fc6772e8b4352641d9 127 Pfam PF08810 Kinase associated protein B 15 126 5.9E-50 T 14-10-2018 IPR014916 Kinase associated protein B C2I25_14600 e9a87a44349ff2fc6772e8b4352641d9 127 Gene3D G3DSA:2.30.30.430 1 127 9.5E-56 T 14-10-2018 IPR038080 Kinase associated protein B superfamily C2I25_14600 e9a87a44349ff2fc6772e8b4352641d9 127 SMART SM01298 15 127 5.6E-75 T 14-10-2018 IPR014916 Kinase associated protein B C2I25_16610 ee477222977f5bcd532035e49dcb5f40 107 SUPERFAMILY SSF54909 1 97 8.05E-25 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_16610 ee477222977f5bcd532035e49dcb5f40 107 Hamap MF_01272 Heme oxygenase (staphylobilin-producing) [isdG]. 1 102 27.195 T 14-10-2018 IPR023953 Heme oxygenase IsdG GO:0004392|GO:0033212|GO:0055114 C2I25_16610 ee477222977f5bcd532035e49dcb5f40 107 Gene3D G3DSA:3.30.70.100 1 106 6.0E-33 T 14-10-2018 C2I25_16610 ee477222977f5bcd532035e49dcb5f40 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.3E-15 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I25_26920 a96f30f53453a2f9fe448c7d6afdc374 364 SUPERFAMILY SSF46689 2 52 1.16E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_26920 a96f30f53453a2f9fe448c7d6afdc374 364 Gene3D G3DSA:1.10.10.60 60 119 3.5E-10 T 14-10-2018 C2I25_26920 a96f30f53453a2f9fe448c7d6afdc374 364 SMART SM00342 19 101 2.9E-16 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_26920 a96f30f53453a2f9fe448c7d6afdc374 364 SUPERFAMILY SSF46689 55 104 7.62E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_26920 a96f30f53453a2f9fe448c7d6afdc374 364 Pfam PF12833 Helix-turn-helix domain 25 101 4.0E-15 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_26920 a96f30f53453a2f9fe448c7d6afdc374 364 Gene3D G3DSA:1.10.10.60 1 56 1.5E-14 T 14-10-2018 C2I25_00350 1d12113711778b3d7ec50025ba4f966c 400 Gene3D G3DSA:3.40.50.1970 1 185 7.0E-64 T 14-10-2018 C2I25_00350 1d12113711778b3d7ec50025ba4f966c 400 SUPERFAMILY SSF56796 6 388 1.57E-126 T 14-10-2018 C2I25_00350 1d12113711778b3d7ec50025ba4f966c 400 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I25_00350 1d12113711778b3d7ec50025ba4f966c 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 379 2.2E-128 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I25_00350 1d12113711778b3d7ec50025ba4f966c 400 Gene3D G3DSA:1.20.1090.10 187 389 7.0E-66 T 14-10-2018 C2I25_04905 e7e37a3eb0c068da62db14e49c89b655 239 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 62.853 T 14-10-2018 IPR022822 Lactate utilization protein A GO:0006089 C2I25_04905 e7e37a3eb0c068da62db14e49c89b655 239 Pfam PF02754 Cysteine-rich domain 3 83 3.7E-18 T 14-10-2018 IPR004017 Cysteine-rich domain C2I25_04905 e7e37a3eb0c068da62db14e49c89b655 239 Pfam PF02754 Cysteine-rich domain 132 215 2.6E-15 T 14-10-2018 IPR004017 Cysteine-rich domain C2I25_24280 4752d2c162b56909618651adcac9183a 253 Pfam PF08241 Methyltransferase domain 56 142 1.2E-6 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_24280 4752d2c162b56909618651adcac9183a 253 SUPERFAMILY SSF53335 17 190 8.95E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_24280 4752d2c162b56909618651adcac9183a 253 Gene3D G3DSA:3.40.50.150 32 194 1.1E-13 T 14-10-2018 C2I25_21235 61b540f776ffb69f400368f203ceaa20 423 TIGRFAM TIGR01224 hutI: imidazolonepropionase 33 409 4.3E-154 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21235 61b540f776ffb69f400368f203ceaa20 423 SUPERFAMILY SSF51556 72 370 1.34E-79 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_21235 61b540f776ffb69f400368f203ceaa20 423 SUPERFAMILY SSF51338 2 416 1.39E-22 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_21235 61b540f776ffb69f400368f203ceaa20 423 Pfam PF01979 Amidohydrolase family 69 411 2.4E-20 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I25_21235 61b540f776ffb69f400368f203ceaa20 423 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 410 42.562 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I25_21235 61b540f776ffb69f400368f203ceaa20 423 Gene3D G3DSA:2.30.40.10 7 408 5.7E-171 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_21235 61b540f776ffb69f400368f203ceaa20 423 Gene3D G3DSA:3.20.20.140 73 370 5.7E-171 T 14-10-2018 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 Gene3D G3DSA:1.20.1250.20 211 399 1.1E-33 T 14-10-2018 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 Pfam PF07690 Major Facilitator Superfamily 12 228 1.8E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 340 363 2.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 106 127 2.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 279 300 2.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 17 33 2.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 136 158 2.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 79 103 2.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 Gene3D G3DSA:1.20.1250.20 2 210 3.0E-43 T 14-10-2018 C2I25_02380 c11d3eaf0294fac422e93544c0205a5e 404 SUPERFAMILY SSF103473 5 392 1.66E-75 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_18245 db1beabd68667c02443858742e7ca966 110 SUPERFAMILY SSF103481 5 99 1.03E-15 T 14-10-2018 C2I25_18245 db1beabd68667c02443858742e7ca966 110 Gene3D G3DSA:1.10.3730.20 1 105 6.3E-22 T 14-10-2018 C2I25_18245 db1beabd68667c02443858742e7ca966 110 Pfam PF00893 Small Multidrug Resistance protein 1 90 1.2E-20 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I25_19955 07822c76ee47b5824f22dd538457c117 256 Gene3D G3DSA:3.40.50.10960 120 235 6.0E-36 T 14-10-2018 C2I25_19955 07822c76ee47b5824f22dd538457c117 256 Pfam PF08478 POTRA domain, FtsQ-type 53 121 5.9E-20 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type C2I25_19955 07822c76ee47b5824f22dd538457c117 256 Hamap MF_00912 Cell division protein DivIB [divIB]. 9 254 31.885 T 14-10-2018 IPR026580 Cell division protein DivIB C2I25_19955 07822c76ee47b5824f22dd538457c117 256 Pfam PF03799 Cell division protein FtsQ 126 240 7.3E-8 T 14-10-2018 IPR005548 Cell division protein FtsQ/DivIB C2I25_19955 07822c76ee47b5824f22dd538457c117 256 Gene3D G3DSA:3.10.20.310 53 119 9.8E-6 T 14-10-2018 C2I25_28465 78b6da78c63084152563b30a3a990540 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 212 1.4E-97 T 14-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 C2I25_28465 78b6da78c63084152563b30a3a990540 220 SMART SM00882 9 205 2.0E-60 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I25_28465 78b6da78c63084152563b30a3a990540 220 Gene3D G3DSA:3.40.1080.10 5 217 5.3E-89 T 14-10-2018 C2I25_28465 78b6da78c63084152563b30a3a990540 220 SUPERFAMILY SSF100950 6 216 3.21E-66 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_28465 78b6da78c63084152563b30a3a990540 220 Pfam PF01144 Coenzyme A transferase 10 202 1.1E-35 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I25_06795 f266c38fe6117f34c2af3449d37ce9d7 494 Gene3D G3DSA:3.40.600.10 4 239 7.8E-39 T 14-10-2018 IPR037057 DNA mismatch repair MutH/Restriction endonuclease, type II superfamily GO:0003677|GO:0004519 C2I25_06795 f266c38fe6117f34c2af3449d37ce9d7 494 SUPERFAMILY SSF52980 246 491 6.43E-31 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I25_06795 f266c38fe6117f34c2af3449d37ce9d7 494 SMART SM00927 56 172 6.0E-19 T 14-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 C2I25_06795 f266c38fe6117f34c2af3449d37ce9d7 494 Pfam PF02976 DNA mismatch repair enzyme MutH 54 172 1.7E-22 T 14-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 C2I25_06795 f266c38fe6117f34c2af3449d37ce9d7 494 Gene3D G3DSA:3.40.600.10 241 455 6.8E-31 T 14-10-2018 IPR037057 DNA mismatch repair MutH/Restriction endonuclease, type II superfamily GO:0003677|GO:0004519 C2I25_06795 f266c38fe6117f34c2af3449d37ce9d7 494 SUPERFAMILY SSF52980 2 236 6.97E-37 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I25_21795 bc370b153a813c973bdc4b982514dad5 617 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 300 612 2.5E-95 T 14-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 C2I25_21795 bc370b153a813c973bdc4b982514dad5 617 Gene3D G3DSA:1.50.10.20 32 298 7.9E-189 T 14-10-2018 C2I25_21795 bc370b153a813c973bdc4b982514dad5 617 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 13 613 3.2E-116 T 14-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 C2I25_21795 bc370b153a813c973bdc4b982514dad5 617 SUPERFAMILY SSF48239 37 294 1.15E-41 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid C2I25_21795 bc370b153a813c973bdc4b982514dad5 617 SUPERFAMILY SSF48239 296 615 8.16E-85 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid C2I25_21795 bc370b153a813c973bdc4b982514dad5 617 Gene3D G3DSA:1.50.10.20 16 611 7.9E-189 T 14-10-2018 C2I25_21795 bc370b153a813c973bdc4b982514dad5 617 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 11 290 2.0E-67 T 14-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 C2I25_00475 8c254381e3ea173999cbd37e90584f4b 194 SUPERFAMILY SSF46689 3 65 1.95E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_00475 8c254381e3ea173999cbd37e90584f4b 194 Gene3D G3DSA:1.10.357.10 5 190 1.9E-22 T 14-10-2018 C2I25_00475 8c254381e3ea173999cbd37e90584f4b 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 4.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_00475 8c254381e3ea173999cbd37e90584f4b 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_00475 8c254381e3ea173999cbd37e90584f4b 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 3.9E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_26985 1c90c6f917a3a58b11a77deb39834ee4 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 127 9.8E-10 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like C2I25_26985 1c90c6f917a3a58b11a77deb39834ee4 159 Gene3D G3DSA:3.30.530.20 3 159 1.7E-35 T 14-10-2018 IPR023393 START-like domain superfamily C2I25_26985 1c90c6f917a3a58b11a77deb39834ee4 159 SUPERFAMILY SSF55961 2 153 6.64E-32 T 14-10-2018 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 4 201 3.5E-58 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 Pfam PF14520 Helix-hairpin-helix domain 70 127 3.6E-15 T 14-10-2018 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 Gene3D G3DSA:1.10.8.10 153 200 6.6E-9 T 14-10-2018 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 Gene3D G3DSA:2.40.50.140 1 63 7.7E-17 T 14-10-2018 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 Pfam PF01330 RuvA N terminal domain 2 60 5.3E-19 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 SMART SM00278 106 125 2.1 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 SMART SM00278 71 90 0.38 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 Gene3D G3DSA:1.10.150.20 65 140 6.9E-24 T 14-10-2018 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 SUPERFAMILY SSF47781 63 135 1.6E-20 T 14-10-2018 IPR010994 RuvA domain 2-like C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 30.275 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 Pfam PF07499 RuvA, C-terminal domain 158 200 6.6E-12 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 SUPERFAMILY SSF46929 157 200 3.01E-10 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily C2I25_17165 e652966d3b1f4c1f94a1effc0dc989af 205 SUPERFAMILY SSF50249 1 61 4.23E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_08295 03c1a227f8439d3e02c222dc621dc60f 276 SMART SM00062 50 273 5.1E-84 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_08295 03c1a227f8439d3e02c222dc621dc60f 276 SUPERFAMILY SSF53850 4 273 1.37E-70 T 14-10-2018 C2I25_08295 03c1a227f8439d3e02c222dc621dc60f 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 272 1.2E-59 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_08295 03c1a227f8439d3e02c222dc621dc60f 276 Gene3D G3DSA:3.40.190.10 51 269 9.2E-84 T 14-10-2018 C2I25_08295 03c1a227f8439d3e02c222dc621dc60f 276 SMART SM00079 50 272 2.4E-6 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 C2I25_08295 03c1a227f8439d3e02c222dc621dc60f 276 Gene3D G3DSA:3.40.190.10 138 235 9.2E-84 T 14-10-2018 C2I25_08295 03c1a227f8439d3e02c222dc621dc60f 276 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 74 87 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 119 25.897 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 119 5.7E-50 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 Gene3D G3DSA:3.30.1390.10 49 119 2.6E-32 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 48 1.1E-20 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 SUPERFAMILY SSF54736 49 119 7.15E-26 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 53 119 8.9E-32 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 SUPERFAMILY SSF48300 1 55 1.07E-16 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 54 119 6.0E-17 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_11025 489e26424ca923853bbcdfdc192f6f87 119 Gene3D G3DSA:1.20.5.710 1 48 1.4E-22 T 14-10-2018 C2I25_14070 8210116d78bbb700e69fcdf7111e78f5 182 Gene3D G3DSA:1.10.10.60 1 50 1.8E-24 T 14-10-2018 C2I25_14070 8210116d78bbb700e69fcdf7111e78f5 182 SUPERFAMILY SSF46689 6 74 1.03E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_14070 8210116d78bbb700e69fcdf7111e78f5 182 SUPERFAMILY SSF48498 79 180 2.76E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_14070 8210116d78bbb700e69fcdf7111e78f5 182 Gene3D G3DSA:1.10.357.10 51 182 5.7E-36 T 14-10-2018 C2I25_14070 8210116d78bbb700e69fcdf7111e78f5 182 Pfam PF13305 WHG domain 85 157 6.8E-13 T 14-10-2018 IPR025996 WHG domain C2I25_12750 42dbee3c9b22d73c4e8cc3a65a815ca1 339 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 7 327 1.7E-126 T 14-10-2018 IPR014225 Sporulation stage II, protein D firmicutes C2I25_12750 42dbee3c9b22d73c4e8cc3a65a815ca1 339 Pfam PF08486 Stage II sporulation protein 65 167 2.3E-27 T 14-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal C2I25_12750 42dbee3c9b22d73c4e8cc3a65a815ca1 339 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 70 326 3.4E-75 T 14-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 C2I25_13350 d28cb8eee589b57928efdcecf57b1cde 122 Pfam PF13411 MerR HTH family regulatory protein 2 68 7.1E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13350 d28cb8eee589b57928efdcecf57b1cde 122 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13350 d28cb8eee589b57928efdcecf57b1cde 122 Gene3D G3DSA:1.10.1660.10 1 121 3.0E-27 T 14-10-2018 C2I25_13350 d28cb8eee589b57928efdcecf57b1cde 122 SMART SM00422 1 69 6.6E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13350 d28cb8eee589b57928efdcecf57b1cde 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.5E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13350 d28cb8eee589b57928efdcecf57b1cde 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.5E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13350 d28cb8eee589b57928efdcecf57b1cde 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.5E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_13350 d28cb8eee589b57928efdcecf57b1cde 122 SUPERFAMILY SSF46955 1 115 2.09E-23 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_07145 138d8e1cacc66ba4fdf7db21df82c88b 112 Gene3D G3DSA:1.10.10.10 14 111 4.5E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_07145 138d8e1cacc66ba4fdf7db21df82c88b 112 Pfam PF01638 HxlR-like helix-turn-helix 26 109 3.1E-28 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_07145 138d8e1cacc66ba4fdf7db21df82c88b 112 SUPERFAMILY SSF46785 13 109 1.96E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_25545 977b0f2f25ae33db977108a845f54f68 115 Gene3D G3DSA:1.10.10.10 1 115 8.5E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25545 977b0f2f25ae33db977108a845f54f68 115 Pfam PF03551 Transcriptional regulator PadR-like family 19 84 1.8E-17 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_25545 977b0f2f25ae33db977108a845f54f68 115 SUPERFAMILY SSF46785 9 108 2.73E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_26965 1e49a00034625469269e4cb5f8820926 483 Pfam PF00144 Beta-lactamase 37 354 2.9E-55 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_26965 1e49a00034625469269e4cb5f8820926 483 Gene3D G3DSA:3.40.710.10 25 361 8.8E-81 T 14-10-2018 C2I25_26965 1e49a00034625469269e4cb5f8820926 483 SUPERFAMILY SSF56601 31 355 1.46E-70 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_06835 a7a2afb7696aa6c5042ecca971537c2a 130 Pfam PF12680 SnoaL-like domain 17 114 4.2E-10 T 14-10-2018 IPR037401 SnoaL-like domain C2I25_06835 a7a2afb7696aa6c5042ecca971537c2a 130 Gene3D G3DSA:3.10.450.50 2 129 9.3E-28 T 14-10-2018 C2I25_06835 a7a2afb7696aa6c5042ecca971537c2a 130 SUPERFAMILY SSF54427 1 129 1.5E-28 T 14-10-2018 IPR032710 NTF2-like domain superfamily C2I25_21975 ca54ad6353a655e4fb8e64dea5a250f4 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 3.4E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_21975 ca54ad6353a655e4fb8e64dea5a250f4 211 SUPERFAMILY SSF46689 11 72 1.13E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_21975 ca54ad6353a655e4fb8e64dea5a250f4 211 Gene3D G3DSA:1.10.10.60 11 60 7.0E-24 T 14-10-2018 C2I25_21975 ca54ad6353a655e4fb8e64dea5a250f4 211 SUPERFAMILY SSF48498 87 206 7.03E-27 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_21975 ca54ad6353a655e4fb8e64dea5a250f4 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_21975 ca54ad6353a655e4fb8e64dea5a250f4 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.7E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_21975 ca54ad6353a655e4fb8e64dea5a250f4 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.7E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_21975 ca54ad6353a655e4fb8e64dea5a250f4 211 Gene3D G3DSA:1.10.357.10 61 211 2.1E-50 T 14-10-2018 C2I25_13835 f440f1705dc243b9732a8dfffb1f52d8 164 PIRSF PIRSF005028 1 162 2.1E-56 T 14-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT C2I25_13835 f440f1705dc243b9732a8dfffb1f52d8 164 SUPERFAMILY SSF116726 77 157 7.06E-18 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_13835 f440f1705dc243b9732a8dfffb1f52d8 164 Gene3D G3DSA:3.30.70.1450 86 161 4.0E-20 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_13835 f440f1705dc243b9732a8dfffb1f52d8 164 Pfam PF02080 TrkA-C domain 89 158 1.9E-16 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I25_02400 4440617a0ab4f00e264fc199daf237d8 420 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 327 418 1.7E-26 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 C2I25_02400 4440617a0ab4f00e264fc199daf237d8 420 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 314 5.6E-77 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_02400 4440617a0ab4f00e264fc199daf237d8 420 Gene3D G3DSA:3.40.50.1100 15 315 3.0E-110 T 14-10-2018 C2I25_02400 4440617a0ab4f00e264fc199daf237d8 420 Gene3D G3DSA:3.40.50.1100 57 156 3.0E-110 T 14-10-2018 C2I25_02400 4440617a0ab4f00e264fc199daf237d8 420 SUPERFAMILY SSF53686 11 362 1.06E-101 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_02400 4440617a0ab4f00e264fc199daf237d8 420 TIGRFAM TIGR02079 THD1: threonine dehydratase 13 420 9.8E-195 T 14-10-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 C2I25_02400 4440617a0ab4f00e264fc199daf237d8 420 Gene3D G3DSA:3.40.1020.10 316 420 3.1E-10 T 14-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 C2I25_02400 4440617a0ab4f00e264fc199daf237d8 420 SUPERFAMILY SSF55021 337 415 8.24E-11 T 14-10-2018 C2I25_18365 61bf10ae63daf3cb1fff844fed65582f 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 68 121 8.0E-20 T 14-10-2018 IPR025664 Stage III sporulation protein AC/AD family C2I25_18365 61bf10ae63daf3cb1fff844fed65582f 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 1 53 1.2E-8 T 14-10-2018 IPR025664 Stage III sporulation protein AC/AD family C2I25_18365 61bf10ae63daf3cb1fff844fed65582f 127 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 124 2.8E-36 T 14-10-2018 IPR014211 Stage III sporulation protein AD C2I25_04400 a67d78f8b8beb01eceff78ba7dd90863 354 SUPERFAMILY SSF53659 2 344 3.07E-117 T 14-10-2018 C2I25_04400 a67d78f8b8beb01eceff78ba7dd90863 354 SMART SM01329 4 340 1.2E-178 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I25_04400 a67d78f8b8beb01eceff78ba7dd90863 354 Gene3D G3DSA:3.40.718.10 1 352 3.1E-137 T 14-10-2018 C2I25_04400 a67d78f8b8beb01eceff78ba7dd90863 354 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 343 3.2E-139 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 C2I25_04400 a67d78f8b8beb01eceff78ba7dd90863 354 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 344 45.834 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 C2I25_04400 a67d78f8b8beb01eceff78ba7dd90863 354 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 341 5.2E-125 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I25_04400 a67d78f8b8beb01eceff78ba7dd90863 354 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 235 254 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 C2I25_09005 50882a2f4ce95bf39a0c12bc38efe308 50 Pfam PF14139 YpzG-like protein 1 49 5.7E-26 T 14-10-2018 IPR025413 YpzG-like protein C2I25_09800 7dd2694e1f6cec57974137061c8a72e6 284 Gene3D G3DSA:3.40.190.10 36 264 2.3E-99 T 14-10-2018 C2I25_09800 7dd2694e1f6cec57974137061c8a72e6 284 Gene3D G3DSA:3.40.190.10 112 222 2.3E-99 T 14-10-2018 C2I25_09800 7dd2694e1f6cec57974137061c8a72e6 284 SUPERFAMILY SSF53850 35 273 1.61E-82 T 14-10-2018 C2I25_09800 7dd2694e1f6cec57974137061c8a72e6 284 Pfam PF03180 NLPA lipoprotein 35 270 1.5E-84 T 14-10-2018 IPR004872 Lipoprotein NlpA family C2I25_09800 7dd2694e1f6cec57974137061c8a72e6 284 PIRSF PIRSF002854 1 274 1.9E-105 T 14-10-2018 IPR004872 Lipoprotein NlpA family C2I25_23560 e402c7a982059cc78c313448fbc785b1 306 Gene3D G3DSA:3.40.50.150 4 305 1.8E-46 T 14-10-2018 C2I25_23560 e402c7a982059cc78c313448fbc785b1 306 SUPERFAMILY SSF53335 9 305 2.77E-61 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_23560 e402c7a982059cc78c313448fbc785b1 306 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 286 4.4E-43 T 14-10-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 C2I25_23560 e402c7a982059cc78c313448fbc785b1 306 Pfam PF04072 Leucine carboxyl methyltransferase 13 207 4.2E-48 T 14-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 C2I25_11380 a61f2e1abc12ece82df6bc8b29f09942 282 Gene3D G3DSA:3.40.50.2020 75 272 1.0E-57 T 14-10-2018 C2I25_11380 a61f2e1abc12ece82df6bc8b29f09942 282 Gene3D G3DSA:1.10.10.10 1 73 1.4E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_11380 a61f2e1abc12ece82df6bc8b29f09942 282 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 269 1.4E-120 T 14-10-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 C2I25_11380 a61f2e1abc12ece82df6bc8b29f09942 282 SUPERFAMILY SSF53271 89 267 1.56E-41 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_11380 a61f2e1abc12ece82df6bc8b29f09942 282 SUPERFAMILY SSF46785 2 74 2.99E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_11380 a61f2e1abc12ece82df6bc8b29f09942 282 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 73 4.0E-31 T 14-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 C2I25_11380 a61f2e1abc12ece82df6bc8b29f09942 282 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 1.9E-32 T 14-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 C2I25_11380 a61f2e1abc12ece82df6bc8b29f09942 282 Pfam PF00156 Phosphoribosyl transferase domain 107 264 4.7E-24 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_01500 5015480fadbad5a1a33c4dfdc279d8e5 156 SUPERFAMILY SSF55729 1 142 1.26E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01500 5015480fadbad5a1a33c4dfdc279d8e5 156 Pfam PF00583 Acetyltransferase (GNAT) family 38 129 2.9E-16 T 14-10-2018 IPR000182 GNAT domain C2I25_01500 5015480fadbad5a1a33c4dfdc279d8e5 156 Gene3D G3DSA:3.40.630.30 44 145 3.1E-24 T 14-10-2018 C2I25_01500 5015480fadbad5a1a33c4dfdc279d8e5 156 Gene3D G3DSA:1.10.287.900 1 42 6.9E-6 T 14-10-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117|MetaCyc: PWY-6922 C2I25_27745 fc6e7eefe817b9c0cf5452567938ed7d 358 PIRSF PIRSF026508 1 358 3.9E-97 T 14-10-2018 IPR008863 Toxic anion resistance C2I25_27745 fc6e7eefe817b9c0cf5452567938ed7d 358 Pfam PF05816 Toxic anion resistance protein (TelA) 46 353 2.5E-54 T 14-10-2018 IPR008863 Toxic anion resistance C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 SUPERFAMILY SSF48557 3 429 1.05E-140 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 Pfam PF10397 Adenylosuccinate lyase C-terminus 352 429 3.1E-26 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 Gene3D G3DSA:1.20.200.10 95 350 1.1E-106 T 14-10-2018 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 Gene3D G3DSA:1.10.40.30 351 435 2.9E-38 T 14-10-2018 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 Pfam PF00206 Lyase 6 288 5.7E-76 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 SMART SM00998 351 431 5.6E-41 T 14-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 2.0E-26 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00149 Fumarate lyase superfamily signature 263 279 2.0E-26 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00149 Fumarate lyase superfamily signature 90 108 2.0E-26 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00149 Fumarate lyase superfamily signature 218 245 2.0E-26 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00145 Argininosuccinate lyase family signature 263 279 9.9E-10 T 14-10-2018 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00145 Argininosuccinate lyase family signature 89 111 9.9E-10 T 14-10-2018 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00145 Argininosuccinate lyase family signature 218 242 9.9E-10 T 14-10-2018 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00145 Argininosuccinate lyase family signature 130 150 9.9E-10 T 14-10-2018 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 ProSitePatterns PS00163 Fumarate lyases signature. 263 272 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 Gene3D G3DSA:1.10.275.10 1 94 2.8E-42 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I25_09930 32a497982f25b13a0ffb875fb7a58f98 435 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 430 1.2E-182 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I25_04985 0327ec3bd2770aec77c6909706cb1468 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 267 3.9E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_04985 0327ec3bd2770aec77c6909706cb1468 282 SUPERFAMILY SSF161098 3 270 9.35E-58 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_04985 0327ec3bd2770aec77c6909706cb1468 282 Gene3D G3DSA:1.10.3720.10 4 275 8.2E-55 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_17050 e7c70bda124cf63dc212c93665f2a012 462 Pfam PF10150 Ribonuclease E/G family 106 364 6.1E-83 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 C2I25_17050 e7c70bda124cf63dc212c93665f2a012 462 SUPERFAMILY SSF50249 38 106 9.14E-12 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_17050 e7c70bda124cf63dc212c93665f2a012 462 Gene3D G3DSA:2.40.50.140 30 109 2.0E-21 T 14-10-2018 C2I25_17050 e7c70bda124cf63dc212c93665f2a012 462 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 398 1.6E-105 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 C2I25_05125 2dfbb6de32928b83a81f1b80c61aa499 639 TIGRFAM TIGR03693 ocin_ThiF_like: putative thiazole-containing bacteriocin maturation protein 1 637 0.0 T 14-10-2018 IPR022368 Putative thiazole-containing bacteriocin maturation protein C2I25_05125 2dfbb6de32928b83a81f1b80c61aa499 639 Gene3D G3DSA:3.40.50.720 187 331 2.1E-10 T 14-10-2018 C2I25_02035 0015ac85e0a762470d59d5918fb8ecc8 301 Pfam PF00892 EamA-like transporter family 151 286 5.7E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_02035 0015ac85e0a762470d59d5918fb8ecc8 301 Pfam PF00892 EamA-like transporter family 11 140 4.3E-25 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_02035 0015ac85e0a762470d59d5918fb8ecc8 301 SUPERFAMILY SSF103481 186 289 3.14E-9 T 14-10-2018 C2I25_02035 0015ac85e0a762470d59d5918fb8ecc8 301 SUPERFAMILY SSF103481 43 143 1.29E-14 T 14-10-2018 C2I25_26790 b865a69d77860b032a75eb2810fad1d0 341 SUPERFAMILY SSF51735 3 176 3.7E-12 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_26790 b865a69d77860b032a75eb2810fad1d0 341 PIRSF PIRSF036497 1 341 2.2E-106 T 14-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_26790 b865a69d77860b032a75eb2810fad1d0 341 Gene3D G3DSA:3.30.360.10 155 318 2.1E-86 T 14-10-2018 C2I25_26790 b865a69d77860b032a75eb2810fad1d0 341 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_26790 b865a69d77860b032a75eb2810fad1d0 341 SUPERFAMILY SSF55347 155 317 2.29E-41 T 14-10-2018 C2I25_26790 b865a69d77860b032a75eb2810fad1d0 341 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 146 1.0E-6 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 C2I25_26790 b865a69d77860b032a75eb2810fad1d0 341 Gene3D G3DSA:3.40.50.720 6 326 2.1E-86 T 14-10-2018 C2I25_26790 b865a69d77860b032a75eb2810fad1d0 341 Pfam PF00742 Homoserine dehydrogenase 158 334 6.7E-49 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I25_24670 0dda594e90eac6c9ce4a9f047772d95b 260 PIRSF PIRSF038992 1 258 4.7E-67 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I25_24670 0dda594e90eac6c9ce4a9f047772d95b 260 Pfam PF01791 DeoC/LacD family aldolase 19 227 7.4E-26 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I25_24670 0dda594e90eac6c9ce4a9f047772d95b 260 SMART SM01133 18 228 2.9E-30 T 14-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I25_24670 0dda594e90eac6c9ce4a9f047772d95b 260 SUPERFAMILY SSF51569 4 243 2.05E-61 T 14-10-2018 C2I25_24670 0dda594e90eac6c9ce4a9f047772d95b 260 Gene3D G3DSA:3.20.20.70 1 260 2.0E-78 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_12590 7955c8602649ee7efbc0f25ca6509ab7 196 SUPERFAMILY SSF110710 12 190 1.54E-78 T 14-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like C2I25_12590 7955c8602649ee7efbc0f25ca6509ab7 196 Hamap MF_00800 UPF0340 protein . 1 196 97.261 T 14-10-2018 IPR006340 Protein of unknown function DUF436 C2I25_12590 7955c8602649ee7efbc0f25ca6509ab7 196 Gene3D G3DSA:3.40.50.10360 10 195 1.0E-80 T 14-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like C2I25_12590 7955c8602649ee7efbc0f25ca6509ab7 196 Pfam PF04260 Protein of unknown function (DUF436) 17 186 6.1E-79 T 14-10-2018 IPR006340 Protein of unknown function DUF436 C2I25_12590 7955c8602649ee7efbc0f25ca6509ab7 196 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 18 190 4.0E-95 T 14-10-2018 IPR006340 Protein of unknown function DUF436 C2I25_12590 7955c8602649ee7efbc0f25ca6509ab7 196 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 16 186 6.7E-76 T 14-10-2018 IPR006340 Protein of unknown function DUF436 C2I25_12590 7955c8602649ee7efbc0f25ca6509ab7 196 PIRSF PIRSF007510 8 189 2.3E-79 T 14-10-2018 IPR006340 Protein of unknown function DUF436 C2I25_20155 d393f186bffdb3a9261f8ce406c37ad8 70 Gene3D G3DSA:3.90.940.10 1 70 3.3E-16 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 C2I25_20155 d393f186bffdb3a9261f8ce406c37ad8 70 SMART SM01409 8 61 1.5E-12 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 C2I25_20155 d393f186bffdb3a9261f8ce406c37ad8 70 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 13.24 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_20155 d393f186bffdb3a9261f8ce406c37ad8 70 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 7.3E-22 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_20155 d393f186bffdb3a9261f8ce406c37ad8 70 Pfam PF01192 RNA polymerase Rpb6 9 59 2.6E-12 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 C2I25_20155 d393f186bffdb3a9261f8ce406c37ad8 70 SUPERFAMILY SSF63562 1 65 6.98E-20 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 C2I25_10575 6524b3e7fa6d27316b92d61f6e61e9b8 305 Gene3D G3DSA:1.10.3720.10 83 298 7.4E-17 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10575 6524b3e7fa6d27316b92d61f6e61e9b8 305 SUPERFAMILY SSF161098 88 290 9.16E-16 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10575 6524b3e7fa6d27316b92d61f6e61e9b8 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 302 1.4E-41 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_01535 84064bc0b2615b1a178f9a50006ef551 333 Gene3D G3DSA:3.20.20.30 1 333 1.2E-97 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_01535 84064bc0b2615b1a178f9a50006ef551 333 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 330 6.5E-125 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 C2I25_01535 84064bc0b2615b1a178f9a50006ef551 333 Pfam PF00296 Luciferase-like monooxygenase 3 300 4.8E-32 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I25_01535 84064bc0b2615b1a178f9a50006ef551 333 SUPERFAMILY SSF51679 2 329 3.18E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_04575 6f899306282e3d57cbc44c0de6fe7f63 391 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 6 388 7.6E-131 T 14-10-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes C2I25_04575 6f899306282e3d57cbc44c0de6fe7f63 391 Gene3D G3DSA:3.40.50.1110 282 388 5.8E-6 T 14-10-2018 IPR036514 SGNH hydrolase superfamily C2I25_04575 6f899306282e3d57cbc44c0de6fe7f63 391 PIRSF PIRSF021438 1 391 4.6E-143 T 14-10-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes C2I25_04575 6f899306282e3d57cbc44c0de6fe7f63 391 Pfam PF04914 DltD protein 40 389 2.3E-123 T 14-10-2018 IPR006998 DltD C2I25_04575 6f899306282e3d57cbc44c0de6fe7f63 391 SUPERFAMILY SSF52266 286 389 1.83E-11 T 14-10-2018 C2I25_19805 3ae93ef20ba5de508cc2c46746f604c6 121 SUPERFAMILY SSF160755 1 114 8.24E-39 T 14-10-2018 IPR036491 YugN-like superfamily C2I25_19805 3ae93ef20ba5de508cc2c46746f604c6 121 Gene3D G3DSA:3.30.310.100 1 121 1.6E-46 T 14-10-2018 IPR036491 YugN-like superfamily C2I25_19805 3ae93ef20ba5de508cc2c46746f604c6 121 Pfam PF08868 YugN-like family 6 93 3.9E-14 T 14-10-2018 IPR014967 Uncharacterised protein family, YugN-like C2I25_19175 b2e464c49ef8d3fddc95a16c3972354c 247 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 244 27.223 T 14-10-2018 IPR003768 Segregation and condensation protein A C2I25_19175 b2e464c49ef8d3fddc95a16c3972354c 247 Pfam PF02616 Segregation and condensation protein ScpA 20 241 2.8E-57 T 14-10-2018 IPR003768 Segregation and condensation protein A C2I25_19175 b2e464c49ef8d3fddc95a16c3972354c 247 Gene3D G3DSA:1.10.10.580 179 242 3.2E-5 T 14-10-2018 IPR023093 ScpA-like, C-terminal C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.9E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 Gene3D G3DSA:3.40.50.720 1 261 6.2E-87 T 14-10-2018 C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 SUPERFAMILY SSF51735 6 253 3.4E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 8.3E-65 T 14-10-2018 C2I25_15670 1f4ff12be6e897a46a2cc61e9a426b74 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_12720 b58faf076341f5531123c565e8603b14 620 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 117 3.5E-19 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 55 79 2.1E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 81 101 2.1E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 411 433 2.1E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 353 375 2.1E-16 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 C2I25_12720 b58faf076341f5531123c565e8603b14 620 Pfam PF00361 Proton-conducting membrane transporter 130 419 3.0E-90 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12720 b58faf076341f5531123c565e8603b14 620 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 612 9.1E-204 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 5.1E-60 T 14-10-2018 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 5.1E-60 T 14-10-2018 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 5.1E-60 T 14-10-2018 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 5.1E-60 T 14-10-2018 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 5.1E-60 T 14-10-2018 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 5.1E-60 T 14-10-2018 C2I25_12720 b58faf076341f5531123c565e8603b14 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 5.1E-60 T 14-10-2018 C2I25_04540 b1b564622ca6cddf9b3f3ed1ca65eb41 148 TIGRFAM TIGR01753 flav_short: flavodoxin 6 144 8.4E-45 T 14-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 C2I25_04540 b1b564622ca6cddf9b3f3ed1ca65eb41 148 Pfam PF00258 Flavodoxin 7 138 2.8E-26 T 14-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 C2I25_04540 b1b564622ca6cddf9b3f3ed1ca65eb41 148 Gene3D G3DSA:3.40.50.360 1 147 2.9E-34 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_04540 b1b564622ca6cddf9b3f3ed1ca65eb41 148 SUPERFAMILY SSF52218 3 147 3.63E-39 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 SUPERFAMILY SSF82829 219 328 1.1E-10 T 14-10-2018 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 Gene3D G3DSA:1.20.59.30 249 336 9.9E-31 T 14-10-2018 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 SUPERFAMILY SSF52402 12 242 1.47E-60 T 14-10-2018 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 25 212 7.0E-60 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 388 433 4.3E-20 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 Pfam PF09179 TilS substrate binding domain 261 329 3.6E-7 T 14-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 Gene3D G3DSA:3.40.50.620 11 242 1.8E-71 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 SUPERFAMILY SSF56037 339 449 6.8E-18 T 14-10-2018 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 9 324 25.608 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 Pfam PF01171 PP-loop family 25 208 8.7E-59 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 SMART SM00977 388 464 4.2E-22 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I25_11285 fe383dc16f36a8b1b7bef44722f6c2bc 476 Pfam PF11734 TilS substrate C-terminal domain 388 455 1.2E-14 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I25_23695 85df586b195c580d2d8924fddbf4c71e 498 Pfam PF03734 L,D-transpeptidase catalytic domain 373 497 1.0E-14 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I25_23695 85df586b195c580d2d8924fddbf4c71e 498 Gene3D G3DSA:2.40.440.10 372 498 6.3E-36 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I25_23695 85df586b195c580d2d8924fddbf4c71e 498 SUPERFAMILY SSF143985 238 357 6.41E-30 T 14-10-2018 IPR038054 L,D-transpeptidase central domain-like superfamily C2I25_23695 85df586b195c580d2d8924fddbf4c71e 498 SUPERFAMILY SSF141523 370 498 3.92E-29 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I25_23695 85df586b195c580d2d8924fddbf4c71e 498 Pfam PF12229 Putative peptidoglycan binding domain 266 344 7.7E-11 T 14-10-2018 IPR022029 Putative peptidoglycan binding domain C2I25_23695 85df586b195c580d2d8924fddbf4c71e 498 Gene3D G3DSA:1.10.269.20 237 357 1.9E-17 T 14-10-2018 IPR038054 L,D-transpeptidase central domain-like superfamily C2I25_27050 7ba5cb8ad22b461127dc30175ee1f1b3 202 Gene3D G3DSA:1.10.3210.10 15 199 7.6E-45 T 14-10-2018 C2I25_27050 7ba5cb8ad22b461127dc30175ee1f1b3 202 TIGRFAM TIGR00277 HDIG: HDIG domain 30 68 3.6E-8 T 14-10-2018 IPR006675 HDIG domain C2I25_27050 7ba5cb8ad22b461127dc30175ee1f1b3 202 SUPERFAMILY SSF109604 13 158 3.14E-23 T 14-10-2018 C2I25_27050 7ba5cb8ad22b461127dc30175ee1f1b3 202 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 31 188 9.4E-27 T 14-10-2018 IPR005249 Conserved hypothetical protein CHP00488 C2I25_27050 7ba5cb8ad22b461127dc30175ee1f1b3 202 Pfam PF01966 HD domain 31 144 2.3E-14 T 14-10-2018 IPR006674 HD domain C2I25_10800 543b84560c6143b1e3eae894ee510d07 130 Gene3D G3DSA:3.30.230.10 4 130 1.5E-52 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I25_10800 543b84560c6143b1e3eae894ee510d07 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 C2I25_10800 543b84560c6143b1e3eae894ee510d07 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.859 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid C2I25_10800 543b84560c6143b1e3eae894ee510d07 130 SUPERFAMILY SSF54211 5 130 7.59E-50 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I25_10800 543b84560c6143b1e3eae894ee510d07 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.1E-46 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 C2I25_27420 32fc45e6b497b97030c9556654a08bd4 417 Pfam PF07690 Major Facilitator Superfamily 19 366 6.7E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_27420 32fc45e6b497b97030c9556654a08bd4 417 SUPERFAMILY SSF103473 12 408 9.81E-48 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_27420 32fc45e6b497b97030c9556654a08bd4 417 Gene3D G3DSA:1.20.1250.20 11 399 1.4E-41 T 14-10-2018 C2I25_16465 eb51b37efb2b3d33a14f18f0df4c6ecb 217 Gene3D G3DSA:2.40.30.170 104 217 3.1E-35 T 14-10-2018 C2I25_16465 eb51b37efb2b3d33a14f18f0df4c6ecb 217 Pfam PF13437 HlyD family secretion protein 94 207 1.2E-13 T 14-10-2018 C2I25_16465 eb51b37efb2b3d33a14f18f0df4c6ecb 217 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 205 217 6.6E-5 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 C2I25_16465 eb51b37efb2b3d33a14f18f0df4c6ecb 217 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 134 158 6.6E-5 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 C2I25_09310 b85a046df9162818b3a92805892fade4 292 SUPERFAMILY SSF53067 3 291 2.01E-59 T 14-10-2018 C2I25_09310 b85a046df9162818b3a92805892fade4 292 Pfam PF00480 ROK family 4 285 1.0E-47 T 14-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I25_09310 b85a046df9162818b3a92805892fade4 292 Gene3D G3DSA:3.30.420.40 1 107 2.8E-22 T 14-10-2018 C2I25_09310 b85a046df9162818b3a92805892fade4 292 Gene3D G3DSA:3.30.420.40 108 292 2.6E-52 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 SUPERFAMILY SSF51905 2 319 6.26E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 Pfam PF00581 Rhodanese-like domain 467 544 7.9E-11 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 4.8E-22 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 4.8E-22 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 4.8E-22 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 4.8E-22 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.8E-22 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 Gene3D G3DSA:3.40.250.10 453 554 4.2E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 Gene3D G3DSA:3.50.50.60 116 443 1.1E-183 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 1.8E-14 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.8E-14 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 1.8E-14 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.8E-14 T 14-10-2018 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 434 1.0E-15 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 SMART SM00450 454 550 1.8E-17 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 307 2.0E-58 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 SUPERFAMILY SSF55424 326 448 1.72E-34 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 SUPERFAMILY SSF52821 437 544 3.4E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 4 443 9.1E-196 T 14-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 C2I25_07465 92577b242b7c48ef149d9c58cb4f9b16 554 Gene3D G3DSA:3.50.50.60 4 343 1.1E-183 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_23710 e5a485f911921a8eb24ed1bcde7760dd 224 Pfam PF00072 Response regulator receiver domain 3 113 1.2E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_23710 e5a485f911921a8eb24ed1bcde7760dd 224 SUPERFAMILY SSF52172 1 178 1.22E-41 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_23710 e5a485f911921a8eb24ed1bcde7760dd 224 SMART SM00862 145 220 7.9E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_23710 e5a485f911921a8eb24ed1bcde7760dd 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 5.1E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_23710 e5a485f911921a8eb24ed1bcde7760dd 224 Gene3D G3DSA:3.40.50.2300 1 121 1.1E-40 T 14-10-2018 C2I25_23710 e5a485f911921a8eb24ed1bcde7760dd 224 Gene3D G3DSA:1.10.10.10 122 224 4.9E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23710 e5a485f911921a8eb24ed1bcde7760dd 224 SMART SM00448 1 112 1.7E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_02075 abf3034f37b1eebf9125a35208700e5d 239 SUPERFAMILY SSF53474 4 229 4.68E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_02075 abf3034f37b1eebf9125a35208700e5d 239 Pfam PF00975 Thioesterase domain 6 224 1.9E-40 T 14-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 C2I25_02075 abf3034f37b1eebf9125a35208700e5d 239 Gene3D G3DSA:3.40.50.1820 3 229 1.3E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_17010 27ea98454d72928483635610339def0f 225 Gene3D G3DSA:3.40.140.10 101 225 1.4E-49 T 14-10-2018 C2I25_17010 27ea98454d72928483635610339def0f 225 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 14-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site C2I25_17010 27ea98454d72928483635610339def0f 225 SUPERFAMILY SSF47781 21 91 2.56E-7 T 14-10-2018 IPR010994 RuvA domain 2-like C2I25_17010 27ea98454d72928483635610339def0f 225 TIGRFAM TIGR00608 radc: DNA repair protein RadC 12 224 7.0E-83 T 14-10-2018 IPR001405 Uncharacterised protein family UPF0758 C2I25_17010 27ea98454d72928483635610339def0f 225 Pfam PF04002 RadC-like JAB domain 104 223 3.3E-49 T 14-10-2018 IPR025657 RadC-like JAB domain C2I25_17010 27ea98454d72928483635610339def0f 225 SUPERFAMILY SSF102712 150 192 5.23E-5 T 14-10-2018 C2I25_20445 ac6addde6dd7b8c10f658c0e1465e312 103 Gene3D G3DSA:3.30.1330.30 1 98 5.1E-38 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_20445 ac6addde6dd7b8c10f658c0e1465e312 103 SUPERFAMILY SSF55315 3 98 2.17E-26 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_20445 ac6addde6dd7b8c10f658c0e1465e312 103 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4 93 1.4E-17 T 14-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 C2I25_08025 f2612e73431816c87ee1fc8e2e32f2db 463 Gene3D G3DSA:1.20.1740.10 10 460 2.3E-66 T 14-10-2018 C2I25_08025 f2612e73431816c87ee1fc8e2e32f2db 463 PIRSF PIRSF006060 1 461 1.6E-74 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_08025 f2612e73431816c87ee1fc8e2e32f2db 463 Pfam PF00324 Amino acid permease 18 448 1.3E-119 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I25_08025 f2612e73431816c87ee1fc8e2e32f2db 463 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I25_03935 218483749acb9412fac48e9624f26b4c 176 SMART SM00644 15 151 4.1E-15 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_03935 218483749acb9412fac48e9624f26b4c 176 Gene3D G3DSA:3.40.80.10 6 174 8.2E-46 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_03935 218483749acb9412fac48e9624f26b4c 176 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 23 151 5.1E-19 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_03935 218483749acb9412fac48e9624f26b4c 176 SUPERFAMILY SSF55846 15 168 7.59E-34 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_07350 c7583798fd172b4c0377dcc937ce097f 427 SUPERFAMILY SSF50685 365 407 4.53E-8 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_07350 c7583798fd172b4c0377dcc937ce097f 427 Gene3D G3DSA:2.30.30.40 31 95 3.9E-18 T 14-10-2018 C2I25_07350 c7583798fd172b4c0377dcc937ce097f 427 Pfam PF06725 3D domain 368 427 5.8E-19 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I25_07350 c7583798fd172b4c0377dcc937ce097f 427 Pfam PF08239 Bacterial SH3 domain 104 154 9.5E-9 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07350 c7583798fd172b4c0377dcc937ce097f 427 Pfam PF08239 Bacterial SH3 domain 44 94 1.9E-12 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07350 c7583798fd172b4c0377dcc937ce097f 427 SMART SM00287 95 158 3.3E-11 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07350 c7583798fd172b4c0377dcc937ce097f 427 SMART SM00287 35 92 3.3E-8 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_07350 c7583798fd172b4c0377dcc937ce097f 427 Gene3D G3DSA:2.30.30.40 96 155 2.3E-14 T 14-10-2018 C2I25_14580 fdaee5654324b0afd15fd6f8d8f3702d 237 Pfam PF08713 DNA alkylation repair enzyme 8 221 9.5E-72 T 14-10-2018 IPR014825 DNA alkylation repair enzyme C2I25_14580 fdaee5654324b0afd15fd6f8d8f3702d 237 SUPERFAMILY SSF48371 12 223 3.31E-59 T 14-10-2018 IPR016024 Armadillo-type fold C2I25_14580 fdaee5654324b0afd15fd6f8d8f3702d 237 Gene3D G3DSA:1.25.10.90 1 237 1.8E-107 T 14-10-2018 C2I25_22615 d934c2fa3063c61c43ae402545ccf2c5 497 SUPERFAMILY SSF56801 3 494 1.57E-136 T 14-10-2018 C2I25_22615 d934c2fa3063c61c43ae402545ccf2c5 497 Pfam PF00501 AMP-binding enzyme 6 401 4.4E-96 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_22615 d934c2fa3063c61c43ae402545ccf2c5 497 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_22615 d934c2fa3063c61c43ae402545ccf2c5 497 Gene3D G3DSA:3.40.50.12780 1 394 1.2E-107 T 14-10-2018 C2I25_22615 d934c2fa3063c61c43ae402545ccf2c5 497 Gene3D G3DSA:3.30.300.310 397 495 5.2E-31 T 14-10-2018 C2I25_22615 d934c2fa3063c61c43ae402545ccf2c5 497 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 484 7.5E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_01430 b8e464094ba91242636e2367833b8d91 459 Pfam PF01943 Polysaccharide biosynthesis protein 7 319 9.4E-40 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I25_01430 b8e464094ba91242636e2367833b8d91 459 PIRSF PIRSF038958 1 458 5.0E-107 T 14-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I25_01430 b8e464094ba91242636e2367833b8d91 459 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 375 455 5.5E-19 T 14-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I25_11425 5acdf31ff9e6bcdd39bafe3f6143e986 94 SMART SM00966 8 51 6.6E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_11425 5acdf31ff9e6bcdd39bafe3f6143e986 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 4.6E-11 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_11425 5acdf31ff9e6bcdd39bafe3f6143e986 94 SUPERFAMILY SSF89447 1 52 1.23E-16 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I25_11425 5acdf31ff9e6bcdd39bafe3f6143e986 94 Gene3D G3DSA:2.10.260.10 1 51 1.4E-26 T 14-10-2018 C2I25_11425 5acdf31ff9e6bcdd39bafe3f6143e986 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 8.8E-12 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_23445 356ba1d0488e2029b60aae3a25d35c9f 83 Gene3D G3DSA:2.60.120.10 1 79 2.6E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_23445 356ba1d0488e2029b60aae3a25d35c9f 83 SUPERFAMILY SSF51182 14 81 1.6E-17 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_23445 356ba1d0488e2029b60aae3a25d35c9f 83 Pfam PF07883 Cupin domain 11 71 2.3E-12 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_27860 b856b0d6a78c35e7b1a4b54720796521 229 Pfam PF03473 MOSC domain 53 159 1.1E-23 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 C2I25_27860 b856b0d6a78c35e7b1a4b54720796521 229 SUPERFAMILY SSF50800 4 217 3.4E-71 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily C2I25_27860 b856b0d6a78c35e7b1a4b54720796521 229 Pfam PF03475 3-alpha domain 173 214 3.0E-14 T 14-10-2018 IPR005163 3-alpha domain C2I25_27860 b856b0d6a78c35e7b1a4b54720796521 229 Gene3D G3DSA:2.40.33.20 1 229 3.1E-74 T 14-10-2018 C2I25_20130 e31ebd79acc406d6a28615e8594cbfc8 569 Gene3D G3DSA:2.30.310.10 1 167 5.0E-67 T 14-10-2018 C2I25_20130 e31ebd79acc406d6a28615e8594cbfc8 569 Pfam PF05670 Domain of unknown function (DUF814) 456 538 5.0E-28 T 14-10-2018 IPR008532 Domain of unknown function DUF814 C2I25_20130 e31ebd79acc406d6a28615e8594cbfc8 569 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 5.1E-162 T 14-10-2018 C2I25_20130 e31ebd79acc406d6a28615e8594cbfc8 569 Gene3D G3DSA:3.40.970.40 243 290 5.8E-18 T 14-10-2018 C2I25_20130 e31ebd79acc406d6a28615e8594cbfc8 569 Gene3D G3DSA:1.10.8.50 168 235 1.6E-26 T 14-10-2018 C2I25_12920 205dc4c2a7c7f87f9978bc890dc9d9e5 226 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_12920 205dc4c2a7c7f87f9978bc890dc9d9e5 226 SMART SM00382 30 217 6.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_12920 205dc4c2a7c7f87f9978bc890dc9d9e5 226 Gene3D G3DSA:3.40.50.300 1 225 1.0E-67 T 14-10-2018 C2I25_12920 205dc4c2a7c7f87f9978bc890dc9d9e5 226 Pfam PF00005 ABC transporter 21 169 1.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_12920 205dc4c2a7c7f87f9978bc890dc9d9e5 226 SUPERFAMILY SSF52540 1 222 1.01E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_10665 d9e0120a595a5458b7713278f235f561 600 Pfam PF01380 SIS domain 287 413 6.6E-33 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I25_10665 d9e0120a595a5458b7713278f235f561 600 Pfam PF01380 SIS domain 457 582 5.7E-17 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I25_10665 d9e0120a595a5458b7713278f235f561 600 Gene3D G3DSA:3.60.20.10 2 239 1.4E-71 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_10665 d9e0120a595a5458b7713278f235f561 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 38.411 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 C2I25_10665 d9e0120a595a5458b7713278f235f561 600 Pfam PF13522 Glutamine amidotransferase domain 62 192 8.3E-19 T 14-10-2018 C2I25_10665 d9e0120a595a5458b7713278f235f561 600 Gene3D G3DSA:3.40.50.10490 243 439 8.5E-65 T 14-10-2018 C2I25_10665 d9e0120a595a5458b7713278f235f561 600 Gene3D G3DSA:3.40.50.10490 444 600 7.5E-61 T 14-10-2018 C2I25_10665 d9e0120a595a5458b7713278f235f561 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 1.5E-225 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 C2I25_10665 d9e0120a595a5458b7713278f235f561 600 SUPERFAMILY SSF56235 2 234 6.26E-64 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_10665 d9e0120a595a5458b7713278f235f561 600 SUPERFAMILY SSF53697 244 600 2.4E-93 T 14-10-2018 C2I25_00495 b5b5e930a7d1cf3ba5e7c54b1e28f7a9 292 SUPERFAMILY SSF53335 4 162 1.49E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_00495 b5b5e930a7d1cf3ba5e7c54b1e28f7a9 292 Pfam PF13847 Methyltransferase domain 38 157 1.4E-21 T 14-10-2018 IPR025714 Methyltransferase domain C2I25_00495 b5b5e930a7d1cf3ba5e7c54b1e28f7a9 292 Gene3D G3DSA:1.10.150.350 147 272 2.4E-115 T 14-10-2018 C2I25_00495 b5b5e930a7d1cf3ba5e7c54b1e28f7a9 292 Gene3D G3DSA:3.40.50.150 17 208 2.4E-115 T 14-10-2018 C2I25_06665 83dc1441b4a413425fa2c8dfdd3a2bde 921 Gene3D G3DSA:2.10.270.10 199 268 2.0E-11 T 14-10-2018 C2I25_06665 83dc1441b4a413425fa2c8dfdd3a2bde 921 Gene3D G3DSA:2.10.270.10 269 373 1.3E-8 T 14-10-2018 C2I25_06665 83dc1441b4a413425fa2c8dfdd3a2bde 921 SUPERFAMILY SSF69360 180 323 7.85E-25 T 14-10-2018 C2I25_06665 83dc1441b4a413425fa2c8dfdd3a2bde 921 Pfam PF00395 S-layer homology domain 154 194 1.3E-13 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06665 83dc1441b4a413425fa2c8dfdd3a2bde 921 Pfam PF00395 S-layer homology domain 37 79 4.7E-9 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06665 83dc1441b4a413425fa2c8dfdd3a2bde 921 Pfam PF00395 S-layer homology domain 95 137 1.1E-9 T 14-10-2018 IPR001119 S-layer homology domain C2I25_20795 b841a4df6d55b567d41fe36c3eb11c3e 191 PIRSF PIRSF000709 2 181 7.6E-5 T 14-10-2018 C2I25_20795 b841a4df6d55b567d41fe36c3eb11c3e 191 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 180 9.1E-25 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I25_20795 b841a4df6d55b567d41fe36c3eb11c3e 191 SUPERFAMILY SSF53254 1 189 2.36E-29 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_20795 b841a4df6d55b567d41fe36c3eb11c3e 191 Gene3D G3DSA:3.40.50.1240 1 187 2.4E-29 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_21050 db9e5996c3e9f73e75789b873052196b 312 Gene3D G3DSA:3.40.190.10 48 280 4.8E-74 T 14-10-2018 C2I25_21050 db9e5996c3e9f73e75789b873052196b 312 SMART SM00062 43 289 8.3E-4 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_21050 db9e5996c3e9f73e75789b873052196b 312 Gene3D G3DSA:3.40.190.10 134 247 4.8E-74 T 14-10-2018 C2I25_21050 db9e5996c3e9f73e75789b873052196b 312 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 48 298 4.9E-66 T 14-10-2018 C2I25_21050 db9e5996c3e9f73e75789b873052196b 312 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 5 271 1.6E-71 T 14-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 C2I25_21050 db9e5996c3e9f73e75789b873052196b 312 SUPERFAMILY SSF53850 41 307 4.2E-51 T 14-10-2018 C2I25_22035 15d54ac032aeb642cca7b3dd31cc9303 319 SUPERFAMILY SSF51735 2 316 1.03E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_22035 15d54ac032aeb642cca7b3dd31cc9303 319 Gene3D G3DSA:3.40.50.720 1 316 4.2E-73 T 14-10-2018 C2I25_22035 15d54ac032aeb642cca7b3dd31cc9303 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 240 8.4E-48 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_02000 e75b7c51fad94cc3c65f2cc0193663ef 337 Pfam PF01594 AI-2E family transporter 16 328 1.9E-44 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like C2I25_17970 57c543fc805780a1f97a478c2999e418 66 SUPERFAMILY SSF158379 1 61 1.7E-22 T 14-10-2018 IPR023164 YqgQ-like superfamily C2I25_17970 57c543fc805780a1f97a478c2999e418 66 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 60 4.0E-27 T 14-10-2018 IPR009256 Protein of unknown function DUF910 C2I25_17970 57c543fc805780a1f97a478c2999e418 66 Gene3D G3DSA:1.10.287.760 1 66 2.6E-26 T 14-10-2018 IPR023164 YqgQ-like superfamily C2I25_01165 6691a5260e9c2c4f3b5c56b434573496 141 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 2 125 6.4E-49 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_01165 6691a5260e9c2c4f3b5c56b434573496 141 PIRSF PIRSF021377 1 140 8.2E-54 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_01165 6691a5260e9c2c4f3b5c56b434573496 141 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 30 116 7.3E-27 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_21355 506b0c39f6d9e6b151eef2874cdba2c1 1071 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 788 1053 2.6E-74 T 14-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain C2I25_21355 506b0c39f6d9e6b151eef2874cdba2c1 1071 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 788 1044 1.1E-39 T 14-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain C2I25_21355 506b0c39f6d9e6b151eef2874cdba2c1 1071 Pfam PF04738 Lantibiotic dehydratase, C terminus 60 713 2.9E-173 T 14-10-2018 IPR006827 Lantibiotic dehydratase, N-terminal C2I25_19810 43092dd06387d854d0bd7ec7d745401e 344 Pfam PF00188 Cysteine-rich secretory protein family 230 334 2.6E-17 T 14-10-2018 IPR014044 CAP domain C2I25_19810 43092dd06387d854d0bd7ec7d745401e 344 Pfam PF14504 CAP-associated N-terminal 60 199 1.8E-47 T 14-10-2018 IPR029410 CAP-associated domain C2I25_19810 43092dd06387d854d0bd7ec7d745401e 344 SUPERFAMILY SSF55797 223 341 6.67E-23 T 14-10-2018 IPR035940 CAP superfamily C2I25_19810 43092dd06387d854d0bd7ec7d745401e 344 Gene3D G3DSA:3.40.33.10 26 344 1.2E-102 T 14-10-2018 IPR035940 CAP superfamily C2I25_27150 f8e5c9985e71d6c1a2ac986d77240c72 217 Gene3D G3DSA:1.10.357.10 12 215 2.5E-39 T 14-10-2018 C2I25_27150 f8e5c9985e71d6c1a2ac986d77240c72 217 SUPERFAMILY SSF46689 15 83 7.18E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_27150 f8e5c9985e71d6c1a2ac986d77240c72 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.3E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_27150 f8e5c9985e71d6c1a2ac986d77240c72 217 SUPERFAMILY SSF48498 103 215 6.67E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_27150 f8e5c9985e71d6c1a2ac986d77240c72 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 4.9E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_27150 f8e5c9985e71d6c1a2ac986d77240c72 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.9E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_13340 7ccb3c0068a1978dcf7067e4abdafe8d 119 Gene3D G3DSA:3.40.50.300 1 117 9.0E-14 T 14-10-2018 C2I25_13340 7ccb3c0068a1978dcf7067e4abdafe8d 119 SUPERFAMILY SSF52540 2 60 2.75E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17080 27a9cc12dfc1d92333119a33bfbfa30a 235 SUPERFAMILY SSF46894 128 226 8.5E-26 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_17080 27a9cc12dfc1d92333119a33bfbfa30a 235 Gene3D G3DSA:3.40.50.2300 2 124 1.0E-28 T 14-10-2018 C2I25_17080 27a9cc12dfc1d92333119a33bfbfa30a 235 Gene3D G3DSA:1.10.10.10 125 227 5.4E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17080 27a9cc12dfc1d92333119a33bfbfa30a 235 SUPERFAMILY SSF52172 1 123 8.54E-34 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_17080 27a9cc12dfc1d92333119a33bfbfa30a 235 Pfam PF00072 Response regulator receiver domain 4 112 1.6E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_17080 27a9cc12dfc1d92333119a33bfbfa30a 235 SMART SM00448 2 112 1.9E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_17080 27a9cc12dfc1d92333119a33bfbfa30a 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 4.5E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_17080 27a9cc12dfc1d92333119a33bfbfa30a 235 SMART SM00862 150 225 1.4E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_13345 dc78e69e8c674c2bda929ba9a861d0c4 179 Pfam PF03358 NADPH-dependent FMN reductase 3 120 2.0E-20 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 C2I25_13345 dc78e69e8c674c2bda929ba9a861d0c4 179 Gene3D G3DSA:3.40.50.360 1 174 1.5E-46 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_13345 dc78e69e8c674c2bda929ba9a861d0c4 179 SUPERFAMILY SSF52218 3 168 5.28E-36 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_13120 09a1c8b3b42bcf3055dfccda1a2ab1ec 451 PIRSF PIRSF006446 1 451 8.4E-107 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I25_13120 09a1c8b3b42bcf3055dfccda1a2ab1ec 451 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 436 3.2E-116 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I25_03370 4f20749429b454677bea514191f952a1 82 ProDom PD062992 CYTOSOLIC YPZA BH2151 1 82 2.0E-41 T 14-10-2018 IPR020314 Uncharacterised protein family YpzA C2I25_03370 4f20749429b454677bea514191f952a1 82 Pfam PF10819 Protein of unknown function (DUF2564) 5 82 2.0E-33 T 14-10-2018 IPR020314 Uncharacterised protein family YpzA C2I25_26960 3111b711768af620a7033ce85b63481f 269 Pfam PF14526 Integron-associated effector binding protein 121 268 1.9E-16 T 14-10-2018 IPR029441 Integron-associated effector binding protein C2I25_26960 3111b711768af620a7033ce85b63481f 269 SMART SM00871 118 269 6.6E-25 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_26960 3111b711768af620a7033ce85b63481f 269 Gene3D G3DSA:1.10.1660.10 1 113 7.2E-26 T 14-10-2018 C2I25_26960 3111b711768af620a7033ce85b63481f 269 SMART SM00422 2 72 2.2E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_26960 3111b711768af620a7033ce85b63481f 269 SUPERFAMILY SSF55136 119 269 1.06E-19 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_26960 3111b711768af620a7033ce85b63481f 269 Gene3D G3DSA:3.20.80.10 114 269 1.9E-23 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_26960 3111b711768af620a7033ce85b63481f 269 SUPERFAMILY SSF46955 2 106 2.38E-24 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_26960 3111b711768af620a7033ce85b63481f 269 Pfam PF13411 MerR HTH family regulatory protein 2 70 9.6E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_16780 092c4739ca531ef7aa110276e4b82ad5 303 SUPERFAMILY SSF52540 12 235 1.7E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16780 092c4739ca531ef7aa110276e4b82ad5 303 Pfam PF00005 ABC transporter 28 166 8.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_16780 092c4739ca531ef7aa110276e4b82ad5 303 Gene3D G3DSA:3.40.50.300 7 244 4.4E-60 T 14-10-2018 C2I25_16780 092c4739ca531ef7aa110276e4b82ad5 303 Pfam PF13732 Domain of unknown function (DUF4162) 220 300 1.8E-14 T 14-10-2018 IPR025302 Domain of unknown function DUF4162 C2I25_16780 092c4739ca531ef7aa110276e4b82ad5 303 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_16780 092c4739ca531ef7aa110276e4b82ad5 303 SMART SM00382 36 214 3.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_01170 3e9f95101e8f7777b625f946f1ec1792 261 Pfam PF00583 Acetyltransferase (GNAT) family 145 251 2.0E-10 T 14-10-2018 IPR000182 GNAT domain C2I25_01170 3e9f95101e8f7777b625f946f1ec1792 261 SUPERFAMILY SSF55729 2 260 2.48E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01170 3e9f95101e8f7777b625f946f1ec1792 261 Gene3D G3DSA:3.40.630.30 57 261 2.7E-22 T 14-10-2018 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 279 4.1E-69 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 400 4.9E-18 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 7.7E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 7.7E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 59 70 7.7E-10 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 SUPERFAMILY SSF56601 1 299 1.07E-74 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 Gene3D G3DSA:3.40.710.10 21 299 8.5E-82 T 14-10-2018 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 Gene3D G3DSA:2.60.410.10 300 400 2.4E-16 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 SUPERFAMILY SSF69189 291 380 7.46E-16 T 14-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_12225 b22fda468846f4adf26a59a835b19a92 423 SMART SM00936 299 400 1.4E-9 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I25_19310 6467001e376231f42015b003ba250b06 353 Gene3D G3DSA:3.40.50.10470 149 352 9.7E-66 T 14-10-2018 C2I25_19310 6467001e376231f42015b003ba250b06 353 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 347 37.745 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I25_19310 6467001e376231f42015b003ba250b06 353 SUPERFAMILY SSF100950 2 342 1.67E-116 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_19310 6467001e376231f42015b003ba250b06 353 Pfam PF01008 Initiation factor 2 subunit family 49 335 4.6E-87 T 14-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 C2I25_19310 6467001e376231f42015b003ba250b06 353 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 2.3E-140 T 14-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I25_19310 6467001e376231f42015b003ba250b06 353 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 36 336 1.7E-122 T 14-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I25_19310 6467001e376231f42015b003ba250b06 353 Gene3D G3DSA:1.20.120.420 2 148 1.2E-50 T 14-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I25_23470 f7afc53dc52bdba89e29390183e65034 415 Pfam PF06245 Protein of unknown function (DUF1015) 4 412 3.3E-142 T 14-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 C2I25_23470 f7afc53dc52bdba89e29390183e65034 415 PIRSF PIRSF033563 1 415 4.3E-164 T 14-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 49 401 1.4E-87 T 14-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 SUPERFAMILY SSF56024 200 391 8.83E-37 T 14-10-2018 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 Gene3D G3DSA:3.30.870.10 47 233 7.2E-37 T 14-10-2018 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 PIRSF PIRSF000850 33 117 0.31 T 14-10-2018 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 PIRSF PIRSF000850 231 304 0.0078 T 14-10-2018 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 PIRSF PIRSF000850 296 372 40.0 T 14-10-2018 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 SUPERFAMILY SSF56024 30 217 5.83E-37 T 14-10-2018 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 SMART SM00155 148 175 3.3 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 SMART SM00155 318 345 3.3E-4 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 Pfam PF13091 PLD-like domain 245 371 1.7E-26 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 Pfam PF13091 PLD-like domain 67 208 6.6E-9 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I25_02630 a98edc47cea99eca3ca7a53be855c4a3 405 Gene3D G3DSA:3.30.870.10 234 383 1.1E-29 T 14-10-2018 C2I25_16195 22a1c77be8e45ac772b7f74934e3a421 262 SUPERFAMILY SSF55729 129 246 2.62E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_16195 22a1c77be8e45ac772b7f74934e3a421 262 Gene3D G3DSA:3.40.630.30 113 246 4.7E-38 T 14-10-2018 C2I25_16195 22a1c77be8e45ac772b7f74934e3a421 262 Pfam PF12746 GNAT acetyltransferase 19 255 1.2E-60 T 14-10-2018 IPR027365 GNAT acetyltransferase YdfB-like C2I25_27445 ba01cbe2265ddc573510d0aca3ed15f5 252 Pfam PF01925 Sulfite exporter TauE/SafE 11 245 2.3E-43 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I25_15220 1ccc53e1c19c2bbecc9a8b2b73954522 78 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 75 1.6E-36 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I25_15220 1ccc53e1c19c2bbecc9a8b2b73954522 78 Pfam PF01809 Haemolytic domain 2 68 4.8E-33 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I25_15220 1ccc53e1c19c2bbecc9a8b2b73954522 78 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.387 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I25_15220 1ccc53e1c19c2bbecc9a8b2b73954522 78 SMART SM01234 1 68 1.8E-50 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I25_15220 1ccc53e1c19c2bbecc9a8b2b73954522 78 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 65 7.0E-24 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I25_00880 badde353d31837918a17cfab28b172f5 118 Pfam PF01381 Helix-turn-helix 7 60 1.2E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_00880 badde353d31837918a17cfab28b172f5 118 SMART SM00530 5 60 8.1E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_00880 badde353d31837918a17cfab28b172f5 118 Gene3D G3DSA:1.10.260.40 1 114 1.3E-26 T 14-10-2018 C2I25_00880 badde353d31837918a17cfab28b172f5 118 SUPERFAMILY SSF47413 2 67 4.02E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_07910 b73b41cb8d611cb00d8239637da62cca 309 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 12 304 1.7E-97 T 14-10-2018 IPR011862 Phosphate binding protein GO:0042301 C2I25_07910 b73b41cb8d611cb00d8239637da62cca 309 Gene3D G3DSA:3.40.190.10 61 303 2.7E-81 T 14-10-2018 C2I25_07910 b73b41cb8d611cb00d8239637da62cca 309 Gene3D G3DSA:3.40.190.10 134 261 2.7E-81 T 14-10-2018 C2I25_07910 b73b41cb8d611cb00d8239637da62cca 309 SUPERFAMILY SSF53850 57 305 3.01E-70 T 14-10-2018 C2I25_07910 b73b41cb8d611cb00d8239637da62cca 309 Pfam PF12849 PBP superfamily domain 52 287 4.0E-36 T 14-10-2018 IPR024370 PBP domain C2I25_16030 3c93c7707228f344fe38ef21d0dc1c6d 212 Gene3D G3DSA:1.10.357.10 1 205 5.1E-38 T 14-10-2018 C2I25_16030 3c93c7707228f344fe38ef21d0dc1c6d 212 SUPERFAMILY SSF46689 3 69 2.51E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_16030 3c93c7707228f344fe38ef21d0dc1c6d 212 SUPERFAMILY SSF48498 77 160 4.13E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_16030 3c93c7707228f344fe38ef21d0dc1c6d 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 4.6E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16030 3c93c7707228f344fe38ef21d0dc1c6d 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 8.8E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16030 3c93c7707228f344fe38ef21d0dc1c6d 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 8.8E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_16030 3c93c7707228f344fe38ef21d0dc1c6d 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_13880 6dfe76309cb2db6198eda6b0e24b07ad 564 SUPERFAMILY SSF58104 225 561 2.35E-75 T 14-10-2018 C2I25_13880 6dfe76309cb2db6198eda6b0e24b07ad 564 Gene3D G3DSA:1.20.1480.50 165 263 5.5E-12 T 14-10-2018 C2I25_13880 6dfe76309cb2db6198eda6b0e24b07ad 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 514 4.7E-46 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_13880 6dfe76309cb2db6198eda6b0e24b07ad 564 Pfam PF00672 HAMP domain 205 254 1.1E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_13880 6dfe76309cb2db6198eda6b0e24b07ad 564 Gene3D G3DSA:1.10.287.950 275 561 1.0E-66 T 14-10-2018 C2I25_13880 6dfe76309cb2db6198eda6b0e24b07ad 564 SMART SM00304 203 257 3.8E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_13880 6dfe76309cb2db6198eda6b0e24b07ad 564 SMART SM00283 286 561 3.1E-79 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I25_12125 e9276788a696ef04ae88f4323601f1cd 223 SUPERFAMILY SSF51206 28 138 4.06E-25 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like C2I25_12125 e9276788a696ef04ae88f4323601f1cd 223 SMART SM00100 15 136 1.8E-8 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_12125 e9276788a696ef04ae88f4323601f1cd 223 Pfam PF00027 Cyclic nucleotide-binding domain 35 120 4.8E-17 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_12125 e9276788a696ef04ae88f4323601f1cd 223 Gene3D G3DSA:2.60.120.1460 10 214 1.0E-25 T 14-10-2018 C2I25_12125 e9276788a696ef04ae88f4323601f1cd 223 SUPERFAMILY SSF46785 151 219 1.39E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_07160 4752e3a3ebc212c69b613c513ec5310b 104 Gene3D G3DSA:1.10.3730.20 1 104 6.1E-19 T 14-10-2018 C2I25_07160 4752e3a3ebc212c69b613c513ec5310b 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 7.4E-23 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I25_07160 4752e3a3ebc212c69b613c513ec5310b 104 SUPERFAMILY SSF103481 4 100 3.53E-14 T 14-10-2018 C2I25_11065 e6fa0906148a58830fda585fc7eba090 170 Pfam PF05991 YacP-like NYN domain 5 167 1.4E-53 T 14-10-2018 IPR010298 Protein of unknown function DUF901 C2I25_07220 fc95a39205c7cf8d091b6dde93924464 294 SUPERFAMILY SSF53697 5 247 2.16E-66 T 14-10-2018 C2I25_07220 fc95a39205c7cf8d091b6dde93924464 294 Pfam PF13580 SIS domain 36 163 2.6E-8 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I25_07220 fc95a39205c7cf8d091b6dde93924464 294 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 5 294 3.9E-114 T 14-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 C2I25_07220 fc95a39205c7cf8d091b6dde93924464 294 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 294 41.899 T 14-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 C2I25_07220 fc95a39205c7cf8d091b6dde93924464 294 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 184 201 - T 14-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 C2I25_07220 fc95a39205c7cf8d091b6dde93924464 294 Gene3D G3DSA:1.10.8.1080 218 294 8.5E-27 T 14-10-2018 C2I25_07220 fc95a39205c7cf8d091b6dde93924464 294 Gene3D G3DSA:3.40.50.10490 1 217 4.2E-73 T 14-10-2018 C2I25_03150 9c407948cb19ff47a8ab3c384efa0dca 135 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 9 127 6.4E-21 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 C2I25_03150 9c407948cb19ff47a8ab3c384efa0dca 135 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site C2I25_03150 9c407948cb19ff47a8ab3c384efa0dca 135 Pfam PF00460 Flagella basal body rod protein 20 35 5.6E-7 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I25_03150 9c407948cb19ff47a8ab3c384efa0dca 135 PIRSF PIRSF002889 8 134 3.2E-19 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 C2I25_04495 0d53d4297db6f426914cfda224b39909 263 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 262 17.614 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I25_04495 0d53d4297db6f426914cfda224b39909 263 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 8 255 1.2E-86 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I25_04495 0d53d4297db6f426914cfda224b39909 263 Pfam PF02673 Bacitracin resistance protein BacA 8 257 8.2E-83 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I25_01245 08d45086853ea01617d3ca0902a20b78 237 Gene3D G3DSA:3.40.50.150 13 228 5.4E-48 T 14-10-2018 C2I25_01245 08d45086853ea01617d3ca0902a20b78 237 Gene3D G3DSA:2.20.25.110 145 206 5.4E-48 T 14-10-2018 C2I25_01245 08d45086853ea01617d3ca0902a20b78 237 Pfam PF13649 Methyltransferase domain 46 137 3.9E-17 T 14-10-2018 C2I25_01245 08d45086853ea01617d3ca0902a20b78 237 SUPERFAMILY SSF53335 10 228 3.41E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_11455 09a787f146d48365711607e8922c6531 327 Pfam PF13177 DNA polymerase III, delta subunit 13 170 3.0E-56 T 14-10-2018 C2I25_11455 09a787f146d48365711607e8922c6531 327 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 17 198 5.1E-62 T 14-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I25_11455 09a787f146d48365711607e8922c6531 327 SUPERFAMILY SSF52540 11 205 1.68E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11455 09a787f146d48365711607e8922c6531 327 Gene3D G3DSA:3.40.50.300 10 170 7.0E-52 T 14-10-2018 C2I25_24025 9b488f395422f1f45e5d6fbcaae1b0c0 316 Gene3D G3DSA:1.20.58.340 243 300 2.6E-14 T 14-10-2018 C2I25_24025 9b488f395422f1f45e5d6fbcaae1b0c0 316 Gene3D G3DSA:1.20.58.340 120 241 5.1E-7 T 14-10-2018 C2I25_24025 9b488f395422f1f45e5d6fbcaae1b0c0 316 Pfam PF01544 CorA-like Mg2+ transporter protein 57 295 3.4E-36 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I25_24025 9b488f395422f1f45e5d6fbcaae1b0c0 316 SUPERFAMILY SSF143865 73 225 4.05E-9 T 14-10-2018 C2I25_24025 9b488f395422f1f45e5d6fbcaae1b0c0 316 SUPERFAMILY SSF144083 236 297 3.53E-17 T 14-10-2018 C2I25_05465 52874a2b78cef56d4a3b22c82c509613 548 Gene3D G3DSA:3.10.105.10 298 519 4.7E-178 T 14-10-2018 C2I25_05465 52874a2b78cef56d4a3b22c82c509613 548 Gene3D G3DSA:3.90.76.10 76 198 4.7E-178 T 14-10-2018 C2I25_05465 52874a2b78cef56d4a3b22c82c509613 548 Gene3D G3DSA:3.40.190.10 57 536 4.7E-178 T 14-10-2018 C2I25_05465 52874a2b78cef56d4a3b22c82c509613 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 468 2.4E-77 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_05465 52874a2b78cef56d4a3b22c82c509613 548 SUPERFAMILY SSF53850 40 542 2.35E-121 T 14-10-2018 C2I25_05465 52874a2b78cef56d4a3b22c82c509613 548 PIRSF PIRSF002741 1 547 2.2E-101 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_19195 e3d85e7c57f24dc38aaaa03ab159cb1a 380 Gene3D G3DSA:2.30.40.10 11 373 4.4E-129 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_19195 e3d85e7c57f24dc38aaaa03ab159cb1a 380 Gene3D G3DSA:3.20.20.140 57 347 4.4E-129 T 14-10-2018 C2I25_19195 e3d85e7c57f24dc38aaaa03ab159cb1a 380 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 5 370 5.3E-102 T 14-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 C2I25_19195 e3d85e7c57f24dc38aaaa03ab159cb1a 380 PIRSF PIRSF038994 1 378 9.5E-117 T 14-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 C2I25_19195 e3d85e7c57f24dc38aaaa03ab159cb1a 380 SUPERFAMILY SSF51338 4 376 3.67E-13 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I25_19195 e3d85e7c57f24dc38aaaa03ab159cb1a 380 SUPERFAMILY SSF51556 57 346 2.57E-93 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_19195 e3d85e7c57f24dc38aaaa03ab159cb1a 380 Pfam PF01979 Amidohydrolase family 53 361 3.1E-23 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I25_20965 8c9ab606e6121e08e18ffdc945418987 317 Pfam PF01715 IPP transferase 42 286 5.2E-83 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 C2I25_20965 8c9ab606e6121e08e18ffdc945418987 317 Gene3D G3DSA:1.10.20.140 116 188 1.7E-105 T 14-10-2018 C2I25_20965 8c9ab606e6121e08e18ffdc945418987 317 Gene3D G3DSA:3.40.50.300 13 291 1.7E-105 T 14-10-2018 C2I25_20965 8c9ab606e6121e08e18ffdc945418987 317 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 294 8.8E-114 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 C2I25_20965 8c9ab606e6121e08e18ffdc945418987 317 SUPERFAMILY SSF52540 11 232 6.91E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20965 8c9ab606e6121e08e18ffdc945418987 317 SUPERFAMILY SSF52540 10 163 2.92E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20965 8c9ab606e6121e08e18ffdc945418987 317 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 303 30.305 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 C2I25_21965 c29347fa758bf0ff5c8e10c0b6153191 410 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 212 395 5.1E-49 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_21965 c29347fa758bf0ff5c8e10c0b6153191 410 SUPERFAMILY SSF53187 210 401 2.95E-52 T 14-10-2018 C2I25_21965 c29347fa758bf0ff5c8e10c0b6153191 410 SMART SM00646 277 395 1.4E-41 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_21965 c29347fa758bf0ff5c8e10c0b6153191 410 Pfam PF00395 S-layer homology domain 149 190 5.7E-8 T 14-10-2018 IPR001119 S-layer homology domain C2I25_21965 c29347fa758bf0ff5c8e10c0b6153191 410 Pfam PF00395 S-layer homology domain 87 129 1.4E-12 T 14-10-2018 IPR001119 S-layer homology domain C2I25_21965 c29347fa758bf0ff5c8e10c0b6153191 410 Pfam PF00395 S-layer homology domain 32 68 1.1E-6 T 14-10-2018 IPR001119 S-layer homology domain C2I25_21965 c29347fa758bf0ff5c8e10c0b6153191 410 Gene3D G3DSA:3.40.630.40 208 404 1.5E-58 T 14-10-2018 C2I25_13040 0c32e3aa89541ffdc00540628ef335c3 294 Gene3D G3DSA:3.20.10.10 134 289 2.1E-57 T 14-10-2018 C2I25_13040 0c32e3aa89541ffdc00540628ef335c3 294 Pfam PF01063 Amino-transferase class IV 39 259 6.2E-45 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 C2I25_13040 0c32e3aa89541ffdc00540628ef335c3 294 SUPERFAMILY SSF56752 22 286 6.02E-77 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 C2I25_13040 0c32e3aa89541ffdc00540628ef335c3 294 Gene3D G3DSA:3.30.470.10 3 127 1.7E-30 T 14-10-2018 C2I25_13040 0c32e3aa89541ffdc00540628ef335c3 294 ProSitePatterns PS00770 Aminotransferases class-IV signature. 187 216 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 C2I25_13040 0c32e3aa89541ffdc00540628ef335c3 294 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 11 284 3.1E-101 T 14-10-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 C2I25_09445 e7be37922efcf96f5d993fe0af971a6a 263 Gene3D G3DSA:3.60.10.10 1 262 1.3E-76 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_09445 e7be37922efcf96f5d993fe0af971a6a 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 254 2.2E-9 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase C2I25_09445 e7be37922efcf96f5d993fe0af971a6a 263 SUPERFAMILY SSF56219 1 261 1.23E-35 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_05010 cb8573275a74c4cd4a9c320157de7e52 107 Pfam PF08671 Anti-repressor SinI 72 99 7.1E-16 T 14-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 C2I25_05010 cb8573275a74c4cd4a9c320157de7e52 107 Gene3D G3DSA:1.10.260.40 1 107 3.6E-33 T 14-10-2018 C2I25_05010 cb8573275a74c4cd4a9c320157de7e52 107 Pfam PF01381 Helix-turn-helix 6 60 1.4E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_05010 cb8573275a74c4cd4a9c320157de7e52 107 SMART SM00530 5 61 2.1E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_05010 cb8573275a74c4cd4a9c320157de7e52 107 SUPERFAMILY SSF47413 2 66 6.48E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_05010 cb8573275a74c4cd4a9c320157de7e52 107 SUPERFAMILY SSF47406 72 106 9.94E-15 T 14-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I25_16105 814c4a359d840222553b4df6a1b10f0a 330 SUPERFAMILY SSF53335 10 310 1.38E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_16105 814c4a359d840222553b4df6a1b10f0a 330 Pfam PF02384 N-6 DNA Methylase 98 319 7.0E-15 T 14-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 C2I25_16105 814c4a359d840222553b4df6a1b10f0a 330 PIRSF PIRSF026567 2 330 1.4E-145 T 14-10-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted C2I25_16105 814c4a359d840222553b4df6a1b10f0a 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 122 136 1.3E-6 T 14-10-2018 C2I25_16105 814c4a359d840222553b4df6a1b10f0a 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 219 243 1.3E-6 T 14-10-2018 C2I25_16105 814c4a359d840222553b4df6a1b10f0a 330 Gene3D G3DSA:3.40.50.150 88 330 3.2E-50 T 14-10-2018 C2I25_16105 814c4a359d840222553b4df6a1b10f0a 330 Gene3D G3DSA:1.10.150.470 1 86 5.3E-26 T 14-10-2018 C2I25_21685 64508002cb63d5ea03b1bf8d827a432e 444 Gene3D G3DSA:1.20.1740.10 1 443 3.7E-131 T 14-10-2018 C2I25_21685 64508002cb63d5ea03b1bf8d827a432e 444 PIRSF PIRSF006060 1 443 1.3E-92 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_21685 64508002cb63d5ea03b1bf8d827a432e 444 Pfam PF13520 Amino acid permease 6 427 4.4E-62 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 Gene3D G3DSA:1.10.287.130 384 459 1.9E-18 T 14-10-2018 C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 504 608 1.7E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 Gene3D G3DSA:3.30.565.10 460 611 4.7E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 SUPERFAMILY SSF158472 325 376 3.92E-7 T 14-10-2018 C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 SUPERFAMILY SSF47384 378 457 3.34E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 Gene3D G3DSA:1.20.1480.50 288 383 9.7E-10 T 14-10-2018 C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 SMART SM00387 501 612 1.9E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 Pfam PF00512 His Kinase A (phospho-acceptor) domain 393 457 1.4E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 SMART SM00304 325 377 5.1E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 SUPERFAMILY SSF55874 446 608 6.29E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23505 d14a48e5753ada8a6c68113ff0039b58 615 SMART SM00388 392 457 2.7E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_08465 1bc1e584f3f18c501f792a9ea5a919c8 420 Pfam PF04294 VanW like protein 238 366 1.9E-45 T 14-10-2018 IPR007391 Vancomycin resistance VanW C2I25_08465 1bc1e584f3f18c501f792a9ea5a919c8 420 Pfam PF12229 Putative peptidoglycan binding domain 87 200 1.1E-11 T 14-10-2018 IPR022029 Putative peptidoglycan binding domain C2I25_08370 5e6b992d0dbfca6fa0ee5e350dfd8336 627 Pfam PF00092 von Willebrand factor type A domain 436 601 2.3E-5 T 14-10-2018 IPR002035 von Willebrand factor, type A C2I25_08370 5e6b992d0dbfca6fa0ee5e350dfd8336 627 Gene3D G3DSA:3.40.50.410 424 622 1.2E-10 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I25_08370 5e6b992d0dbfca6fa0ee5e350dfd8336 627 SMART SM00327 431 622 3.8E-9 T 14-10-2018 IPR002035 von Willebrand factor, type A C2I25_08370 5e6b992d0dbfca6fa0ee5e350dfd8336 627 SUPERFAMILY SSF53300 435 621 1.28E-15 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I25_04030 51baec6f60cad10a6715bd2e956fa04e 541 Pfam PF05140 ResB-like family 65 430 9.5E-74 T 14-10-2018 IPR007816 ResB-like domain C2I25_04030 51baec6f60cad10a6715bd2e956fa04e 541 Pfam PF05140 ResB-like family 439 519 3.6E-16 T 14-10-2018 IPR007816 ResB-like domain C2I25_05340 4079d2df79d86756eca4d7f0be97998f 229 Pfam PF13489 Methyltransferase domain 29 178 1.9E-17 T 14-10-2018 C2I25_05340 4079d2df79d86756eca4d7f0be97998f 229 SUPERFAMILY SSF53335 14 194 8.96E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_05340 4079d2df79d86756eca4d7f0be97998f 229 Gene3D G3DSA:3.40.50.150 19 229 1.2E-65 T 14-10-2018 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 Gene3D G3DSA:3.30.465.10 91 217 1.3E-43 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 Pfam PF01565 FAD binding domain 38 166 3.5E-27 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 Gene3D G3DSA:3.90.78.10 218 305 9.7E-35 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 300 1.1E-29 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 SUPERFAMILY SSF56194 200 302 1.19E-37 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 SUPERFAMILY SSF56176 3 194 2.29E-48 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 Gene3D G3DSA:3.30.43.10 1 89 4.5E-27 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 301 6.1E-78 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_13715 32e37046d197ff9bda52c373c67c3ad9 305 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 305 95.683 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I25_23540 900bd2c4a97ead383765a800a15f8b99 354 Pfam PF02687 FtsX-like permease family 261 344 3.4E-6 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_06370 b0347bbee9fdb74ee9f090150c550410 328 Gene3D G3DSA:3.60.60.10 2 328 4.2E-118 T 14-10-2018 C2I25_06370 b0347bbee9fdb74ee9f090150c550410 328 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 316 1.5E-112 T 14-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal C2I25_06370 b0347bbee9fdb74ee9f090150c550410 328 SUPERFAMILY SSF56235 2 328 8.49E-116 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_06735 88d7e0d5c5b2e621b2c89288b42e11a8 247 SUPERFAMILY SSF46955 5 123 2.78E-26 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_06735 88d7e0d5c5b2e621b2c89288b42e11a8 247 SMART SM00422 3 72 1.1E-21 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_06735 88d7e0d5c5b2e621b2c89288b42e11a8 247 Pfam PF13411 MerR HTH family regulatory protein 5 69 2.9E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_06735 88d7e0d5c5b2e621b2c89288b42e11a8 247 Gene3D G3DSA:1.10.1660.10 1 143 1.9E-30 T 14-10-2018 C2I25_27985 4bd214efce0858cdf47e19af1963b92f 743 SUPERFAMILY SSF82866 541 728 3.14E-29 T 14-10-2018 C2I25_27985 4bd214efce0858cdf47e19af1963b92f 743 Pfam PF03176 MMPL family 496 730 1.1E-45 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I25_27985 4bd214efce0858cdf47e19af1963b92f 743 Pfam PF03176 MMPL family 51 405 2.1E-59 T 14-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I25_27985 4bd214efce0858cdf47e19af1963b92f 743 SUPERFAMILY SSF82866 176 360 5.49E-29 T 14-10-2018 C2I25_27985 4bd214efce0858cdf47e19af1963b92f 743 PRINTS PR00702 Acriflavin resistance protein family signature 195 218 8.5E-5 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_27985 4bd214efce0858cdf47e19af1963b92f 743 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 8.5E-5 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I25_27985 4bd214efce0858cdf47e19af1963b92f 743 Gene3D G3DSA:1.20.1640.10 184 361 2.2E-6 T 14-10-2018 C2I25_06045 831dcefd8e8b65988c1f290b00c626c6 311 TIGRFAM TIGR00109 hemH: ferrochelatase 2 307 1.7E-96 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I25_06045 831dcefd8e8b65988c1f290b00c626c6 311 ProSitePatterns PS00534 Ferrochelatase signature. 177 195 - T 14-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I25_06045 831dcefd8e8b65988c1f290b00c626c6 311 SUPERFAMILY SSF53800 2 305 1.26E-88 T 14-10-2018 C2I25_06045 831dcefd8e8b65988c1f290b00c626c6 311 Gene3D G3DSA:3.40.50.1400 147 288 7.4E-111 T 14-10-2018 C2I25_06045 831dcefd8e8b65988c1f290b00c626c6 311 Pfam PF00762 Ferrochelatase 4 306 2.2E-82 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I25_06045 831dcefd8e8b65988c1f290b00c626c6 311 Gene3D G3DSA:3.40.50.1400 7 303 7.4E-111 T 14-10-2018 C2I25_06045 831dcefd8e8b65988c1f290b00c626c6 311 Hamap MF_00323 Ferrochelatase [hemH]. 3 307 30.679 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I25_16870 2b6f19ad8a0d6e394c4610d0832880ff 167 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 148 3.2E-31 T 14-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 C2I25_16870 2b6f19ad8a0d6e394c4610d0832880ff 167 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 145 7.2E-32 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 C2I25_16870 2b6f19ad8a0d6e394c4610d0832880ff 167 Gene3D G3DSA:3.60.21.10 1 165 5.5E-46 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_16870 2b6f19ad8a0d6e394c4610d0832880ff 167 SUPERFAMILY SSF56300 1 162 3.21E-44 T 14-10-2018 C2I25_09030 2c762076b6ae48845e557cee103e0a78 185 Gene3D G3DSA:3.40.630.30 1 178 6.5E-21 T 14-10-2018 C2I25_09030 2c762076b6ae48845e557cee103e0a78 185 Pfam PF13302 Acetyltransferase (GNAT) domain 7 132 9.0E-13 T 14-10-2018 IPR000182 GNAT domain C2I25_09030 2c762076b6ae48845e557cee103e0a78 185 SUPERFAMILY SSF55729 3 156 5.31E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_10520 418be63d583e3a7f70cecd8396e74db3 216 Pfam PF04973 Nicotinamide mononucleotide transporter 25 203 5.8E-42 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 C2I25_10520 418be63d583e3a7f70cecd8396e74db3 216 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 24 207 7.7E-46 T 14-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 C2I25_02905 613f275a4c3348b4309444dd1f68fb1f 277 Gene3D G3DSA:2.40.320.10 32 255 4.1E-6 T 14-10-2018 C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 SUPERFAMILY SSF50685 234 286 6.98E-11 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 Pfam PF08239 Bacterial SH3 domain 36 84 3.7E-11 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 Pfam PF08239 Bacterial SH3 domain 95 142 8.8E-9 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 Gene3D G3DSA:2.30.30.40 23 87 1.7E-15 T 14-10-2018 C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 Pfam PF06725 3D domain 236 296 6.1E-21 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 SMART SM00287 89 148 1.9E-7 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 SMART SM00287 27 88 4.9E-8 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 Gene3D G3DSA:2.40.40.10 146 290 4.4E-9 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_12995 32cd4a2dc2b5d5cd4f07246af042aff1 296 Gene3D G3DSA:2.30.30.40 88 145 3.4E-14 T 14-10-2018 C2I25_04935 9df3c72c682d2a3e8a278ebd68627dd4 470 Gene3D G3DSA:3.30.70.2740 336 417 2.3E-14 T 14-10-2018 C2I25_04935 9df3c72c682d2a3e8a278ebd68627dd4 470 Pfam PF01565 FAD binding domain 41 180 1.0E-42 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I25_04935 9df3c72c682d2a3e8a278ebd68627dd4 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 1.3E-180 T 14-10-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 C2I25_04935 9df3c72c682d2a3e8a278ebd68627dd4 470 SUPERFAMILY SSF55103 220 460 1.01E-70 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 C2I25_04935 9df3c72c682d2a3e8a278ebd68627dd4 470 Gene3D G3DSA:3.30.465.40 3 237 1.2E-78 T 14-10-2018 C2I25_04935 9df3c72c682d2a3e8a278ebd68627dd4 470 SUPERFAMILY SSF56176 5 217 1.07E-75 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_04935 9df3c72c682d2a3e8a278ebd68627dd4 470 Gene3D G3DSA:1.10.45.10 418 457 1.5E-11 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 C2I25_04935 9df3c72c682d2a3e8a278ebd68627dd4 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 456 4.1E-74 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 C2I25_24530 64a4f0539bf2294275e1e62796ad1709 442 Gene3D G3DSA:3.30.565.10 286 436 1.9E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_24530 64a4f0539bf2294275e1e62796ad1709 442 SUPERFAMILY SSF55874 300 416 6.57E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_24530 64a4f0539bf2294275e1e62796ad1709 442 Pfam PF14501 GHKL domain 334 434 7.2E-12 T 14-10-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain C2I25_15860 b1ad6db0965cfa9d54f38cdbffa65f09 170 Pfam PF06103 Bacterial protein of unknown function (DUF948) 7 94 1.6E-27 T 14-10-2018 IPR009293 Uncharacterised protein family UPF0478 C2I25_00870 42268f44c2787ad368de7b9fa953fe07 99 Pfam PF12728 Helix-turn-helix domain 33 81 2.5E-6 T 14-10-2018 C2I25_00335 f130d4c31718cd96691bc63739873bff 146 Pfam PF00583 Acetyltransferase (GNAT) family 32 133 1.3E-15 T 14-10-2018 IPR000182 GNAT domain C2I25_00335 f130d4c31718cd96691bc63739873bff 146 Gene3D G3DSA:3.40.630.30 1 139 9.7E-36 T 14-10-2018 C2I25_00335 f130d4c31718cd96691bc63739873bff 146 SUPERFAMILY SSF55729 1 143 1.89E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_12500 a7609c4f982493499917170b10a4bb92 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 310 1.1E-144 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I25_12500 a7609c4f982493499917170b10a4bb92 321 SUPERFAMILY SSF56655 2 313 1.53E-112 T 14-10-2018 C2I25_12500 a7609c4f982493499917170b10a4bb92 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 321 3.7E-155 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I25_12500 a7609c4f982493499917170b10a4bb92 321 Gene3D G3DSA:3.30.540.10 7 310 7.8E-136 T 14-10-2018 C2I25_12500 a7609c4f982493499917170b10a4bb92 321 PIRSF PIRSF004532 1 321 1.0E-151 T 14-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I25_12500 a7609c4f982493499917170b10a4bb92 321 Gene3D G3DSA:3.40.190.90 122 284 7.8E-136 T 14-10-2018 C2I25_26720 fcdc929c4638f6b5e6c43ae094f4dd1c 80 SUPERFAMILY SSF47413 1 67 7.88E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_26720 fcdc929c4638f6b5e6c43ae094f4dd1c 80 Gene3D G3DSA:1.10.260.40 1 66 3.0E-19 T 14-10-2018 C2I25_26720 fcdc929c4638f6b5e6c43ae094f4dd1c 80 SMART SM00530 6 62 3.2E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_26720 fcdc929c4638f6b5e6c43ae094f4dd1c 80 Pfam PF01381 Helix-turn-helix 7 62 7.8E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_26255 f4b54da5baea1ef25eca24e39f13c110 265 SMART SM00871 123 265 3.6E-10 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_26255 f4b54da5baea1ef25eca24e39f13c110 265 Pfam PF13411 MerR HTH family regulatory protein 3 70 1.9E-12 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_26255 f4b54da5baea1ef25eca24e39f13c110 265 SMART SM00422 2 72 1.2E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_26255 f4b54da5baea1ef25eca24e39f13c110 265 SUPERFAMILY SSF46955 2 104 1.87E-22 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_26255 f4b54da5baea1ef25eca24e39f13c110 265 SUPERFAMILY SSF55136 149 265 6.67E-14 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_26255 f4b54da5baea1ef25eca24e39f13c110 265 Gene3D G3DSA:1.10.1660.10 1 127 1.6E-24 T 14-10-2018 C2I25_26255 f4b54da5baea1ef25eca24e39f13c110 265 Pfam PF06445 GyrI-like small molecule binding domain 181 265 1.2E-7 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain C2I25_26255 f4b54da5baea1ef25eca24e39f13c110 265 Gene3D G3DSA:3.20.80.10 128 265 1.9E-14 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_15580 526856893e89bb185420ff5f4e85d20a 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 360 9.2E-49 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_15580 526856893e89bb185420ff5f4e85d20a 366 Pfam PF03845 Spore germination protein 9 326 2.4E-104 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_02025 def266f6666f4456a9211f201712b529 143 SUPERFAMILY SSF46785 2 137 1.17E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02025 def266f6666f4456a9211f201712b529 143 Pfam PF02082 Transcriptional regulator 1 81 1.6E-23 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type C2I25_02025 def266f6666f4456a9211f201712b529 143 Gene3D G3DSA:1.10.10.10 1 143 2.4E-60 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 SMART SM00304 185 237 7.8E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 SUPERFAMILY SSF158472 186 235 2.22E-11 T 14-10-2018 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 Gene3D G3DSA:1.10.287.130 234 301 1.3E-20 T 14-10-2018 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 Gene3D G3DSA:1.10.8.500 184 233 2.2E-12 T 14-10-2018 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 SMART SM00387 348 458 9.9E-37 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 Pfam PF00672 HAMP domain 186 233 2.3E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 2.7E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 2.7E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 2.7E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 2.7E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 SUPERFAMILY SSF55874 294 458 4.71E-44 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 Gene3D G3DSA:3.30.565.10 302 458 3.5E-45 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 457 8.8E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 303 2.2E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 SMART SM00388 238 304 1.1E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I25_23520 9a6a28fdb505abd1d08a35b5ffd3a7f9 458 SUPERFAMILY SSF47384 221 303 1.12E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I25_25590 f8398afd2932df145fa7bd3c4f2c026e 167 SUPERFAMILY SSF52540 1 99 1.5E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25590 f8398afd2932df145fa7bd3c4f2c026e 167 Gene3D G3DSA:3.40.50.300 1 166 4.7E-16 T 14-10-2018 C2I25_24360 633ae44c6a99a56ad554d6d5e63c5fe4 155 Gene3D G3DSA:3.90.79.10 3 145 1.9E-29 T 14-10-2018 C2I25_24360 633ae44c6a99a56ad554d6d5e63c5fe4 155 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_24360 633ae44c6a99a56ad554d6d5e63c5fe4 155 Pfam PF00293 NUDIX domain 19 127 2.8E-9 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_24360 633ae44c6a99a56ad554d6d5e63c5fe4 155 SUPERFAMILY SSF55811 7 143 1.62E-21 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_26850 e3b78cda7fd9da6dbc67c42529775a5e 142 Pfam PF07486 Cell Wall Hydrolase 24 129 1.6E-15 T 14-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I25_26850 e3b78cda7fd9da6dbc67c42529775a5e 142 Gene3D G3DSA:1.10.10.2520 8 92 5.2E-13 T 14-10-2018 C2I25_00875 d9a8e39880c0193f48bd1057dff1c246 62 Pfam PF01381 Helix-turn-helix 6 53 2.9E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_00875 d9a8e39880c0193f48bd1057dff1c246 62 SMART SM00530 4 59 3.0E-9 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_00875 d9a8e39880c0193f48bd1057dff1c246 62 Gene3D G3DSA:1.10.260.40 1 62 3.1E-13 T 14-10-2018 C2I25_00875 d9a8e39880c0193f48bd1057dff1c246 62 SUPERFAMILY SSF47413 3 61 5.63E-13 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_24570 ad5abfc6992720ae6396ed9409a20482 276 Pfam PF04294 VanW like protein 72 204 3.4E-41 T 14-10-2018 IPR007391 Vancomycin resistance VanW C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 Gene3D G3DSA:1.10.10.10 1 83 1.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 Gene3D G3DSA:3.40.190.10 162 267 9.1E-41 T 14-10-2018 C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 Gene3D G3DSA:3.40.190.10 90 289 9.1E-41 T 14-10-2018 C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 SUPERFAMILY SSF46785 1 84 1.41E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 SUPERFAMILY SSF53850 87 294 4.81E-41 T 14-10-2018 C2I25_22315 efeb615f25e68c0116f90a7b86a4baf1 297 Pfam PF03466 LysR substrate binding domain 86 292 1.0E-44 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_26650 e2e6ee073a0940d928492a08174d8f25 180 Pfam PF00589 Phage integrase family 10 167 8.0E-25 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_26650 e2e6ee073a0940d928492a08174d8f25 180 SUPERFAMILY SSF56349 6 177 1.27E-36 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_26650 e2e6ee073a0940d928492a08174d8f25 180 Gene3D G3DSA:1.10.443.10 5 180 1.3E-31 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 3.5E-134 T 14-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 Gene3D G3DSA:3.40.50.720 2 147 1.9E-59 T 14-10-2018 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 314 47.924 T 14-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 1.2E-49 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 SUPERFAMILY SSF51735 4 145 1.56E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 14-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 PIRSF PIRSF000102 2 313 1.3E-114 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 6.0E-49 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 6.0E-49 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 6.0E-49 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 6.0E-49 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 6.0E-49 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 SUPERFAMILY SSF56327 146 312 5.91E-58 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 311 8.3E-38 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 C2I25_01995 80d190edb388fa1eb1d5393a29631e93 314 Gene3D G3DSA:3.90.110.10 148 313 3.2E-63 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I25_18740 d798e614271f94cf46278417314e9d21 279 SUPERFAMILY SSF51735 5 162 5.34E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_18740 d798e614271f94cf46278417314e9d21 279 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 268 26.125 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_18740 d798e614271f94cf46278417314e9d21 279 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 268 9.2E-84 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_18740 d798e614271f94cf46278417314e9d21 279 PIRSF PIRSF000193 3 271 1.2E-80 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_18740 d798e614271f94cf46278417314e9d21 279 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 268 1.2E-36 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_18740 d798e614271f94cf46278417314e9d21 279 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 1.2E-17 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I25_18740 d798e614271f94cf46278417314e9d21 279 Gene3D G3DSA:3.40.50.720 2 165 2.0E-46 T 14-10-2018 C2I25_18740 d798e614271f94cf46278417314e9d21 279 SUPERFAMILY SSF48179 163 271 7.82E-36 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_18740 d798e614271f94cf46278417314e9d21 279 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 224 246 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I25_18740 d798e614271f94cf46278417314e9d21 279 Gene3D G3DSA:1.10.3730.10 166 273 1.7E-41 T 14-10-2018 C2I25_16215 3d0a08b79ff30525702131d121c0bcd2 275 Pfam PF10978 Protein of unknown function (DUF2785) 76 249 6.8E-50 T 14-10-2018 IPR021247 Protein of unknown function DUF2785 C2I25_22860 ff74e19d2cff31184bc7b66dee772709 189 Gene3D G3DSA:3.40.50.1000 1 173 5.8E-30 T 14-10-2018 IPR023214 HAD superfamily C2I25_22860 ff74e19d2cff31184bc7b66dee772709 189 PIRSF PIRSF021362 1 189 2.5E-74 T 14-10-2018 IPR009206 Nucleotidase, putative C2I25_22860 ff74e19d2cff31184bc7b66dee772709 189 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 4 185 5.9E-10 T 14-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 C2I25_22860 ff74e19d2cff31184bc7b66dee772709 189 SUPERFAMILY SSF56784 3 180 2.42E-26 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_04020 0379bdb4fd4a30de5632b76c053c0874 238 Gene3D G3DSA:1.10.10.10 136 237 2.6E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04020 0379bdb4fd4a30de5632b76c053c0874 238 SMART SM00448 5 115 5.1E-46 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_04020 0379bdb4fd4a30de5632b76c053c0874 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 9.1E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_04020 0379bdb4fd4a30de5632b76c053c0874 238 Gene3D G3DSA:3.40.50.2300 3 126 1.8E-40 T 14-10-2018 C2I25_04020 0379bdb4fd4a30de5632b76c053c0874 238 Pfam PF00072 Response regulator receiver domain 7 115 2.3E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_04020 0379bdb4fd4a30de5632b76c053c0874 238 SUPERFAMILY SSF52172 3 124 3.13E-42 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_04020 0379bdb4fd4a30de5632b76c053c0874 238 SMART SM00862 156 233 2.1E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_04020 0379bdb4fd4a30de5632b76c053c0874 238 SUPERFAMILY SSF46894 133 234 1.91E-31 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_04930 d4163543f58919adb5a67c5b69eab537 371 SUPERFAMILY SSF46689 259 335 1.54E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_04930 d4163543f58919adb5a67c5b69eab537 371 Pfam PF13556 PucR C-terminal helix-turn-helix domain 301 358 8.0E-20 T 14-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain C2I25_04930 d4163543f58919adb5a67c5b69eab537 371 Gene3D G3DSA:1.10.10.2840 242 363 7.9E-21 T 14-10-2018 C2I25_04930 d4163543f58919adb5a67c5b69eab537 371 Pfam PF05651 Putative sugar diacid recognition 5 135 1.3E-48 T 14-10-2018 IPR008599 Putative sugar diacid recognition C2I25_03310 8c1c14a5bf03576f7fcd97cb28a11316 451 PIRSF PIRSF006603 1 440 9.8E-74 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_03310 8c1c14a5bf03576f7fcd97cb28a11316 451 Pfam PF01554 MatE 255 404 4.8E-18 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_03310 8c1c14a5bf03576f7fcd97cb28a11316 451 Pfam PF01554 MatE 22 183 4.4E-27 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_03310 8c1c14a5bf03576f7fcd97cb28a11316 451 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 416 6.1E-53 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_21185 4e5d14e0072c531036d7b79a4c9e6b3c 168 PIRSF PIRSF021441 1 161 2.0E-73 T 14-10-2018 IPR031306 CcdC protein C2I25_21185 4e5d14e0072c531036d7b79a4c9e6b3c 168 Pfam PF07301 Protein of unknown function (DUF1453) 6 149 3.6E-61 T 14-10-2018 IPR009916 Protein of unknown function DUF1453 C2I25_20895 5e884e63084022f9a26bdf5cf0d87a6e 297 SUPERFAMILY SSF56300 64 291 3.94E-38 T 14-10-2018 C2I25_20895 5e884e63084022f9a26bdf5cf0d87a6e 297 Gene3D G3DSA:3.60.21.10 64 265 1.8E-26 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_20895 5e884e63084022f9a26bdf5cf0d87a6e 297 Pfam PF00149 Calcineurin-like phosphoesterase 64 229 1.4E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_21740 a1d002024f2811f0c250bd85c9ea36aa 259 Pfam PF01226 Formate/nitrite transporter 8 248 1.6E-72 T 14-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 C2I25_21740 a1d002024f2811f0c250bd85c9ea36aa 259 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 161 171 - T 14-10-2018 IPR024002 Formate/nitrite transporter, conserved site C2I25_21740 a1d002024f2811f0c250bd85c9ea36aa 259 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 77 86 - T 14-10-2018 IPR024002 Formate/nitrite transporter, conserved site C2I25_21740 a1d002024f2811f0c250bd85c9ea36aa 259 Gene3D G3DSA:1.20.1080.10 4 259 1.7E-77 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 Gene3D G3DSA:3.40.50.1820 1 278 2.9E-95 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 9.9E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 9.9E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 9.9E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 SUPERFAMILY SSF53474 13 277 4.39E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 Pfam PF00561 alpha/beta hydrolase fold 25 258 7.0E-28 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 7.7E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 PRINTS PR00412 Epoxide hydrolase signature 31 49 7.7E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 7.7E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_24060 5b684bf5019496c8e69809157bf7e520 278 PRINTS PR00412 Epoxide hydrolase signature 51 66 7.7E-11 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_06865 98cc401c7e4b832839433efbfb570e82 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 7.1E-47 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_06865 98cc401c7e4b832839433efbfb570e82 316 SUPERFAMILY SSF161098 92 296 3.92E-20 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_06865 98cc401c7e4b832839433efbfb570e82 316 Gene3D G3DSA:1.10.3720.10 85 308 2.9E-25 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07240 06249e849f82e0ffae5e4e68a9d015db 467 PIRSF PIRSF006060 6 467 4.2E-102 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_07240 06249e849f82e0ffae5e4e68a9d015db 467 Gene3D G3DSA:1.20.1740.10 17 466 7.6E-138 T 14-10-2018 C2I25_07240 06249e849f82e0ffae5e4e68a9d015db 467 Pfam PF13520 Amino acid permease 24 437 1.4E-63 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_04110 87ce7ff9b41aee3ebb1c174c769efcd9 281 SUPERFAMILY SSF117396 2 267 3.53E-84 T 14-10-2018 IPR036520 UPF0759 superfamily C2I25_04110 87ce7ff9b41aee3ebb1c174c769efcd9 281 Gene3D G3DSA:3.20.20.410 1 280 9.6E-93 T 14-10-2018 IPR036520 UPF0759 superfamily C2I25_04110 87ce7ff9b41aee3ebb1c174c769efcd9 281 Pfam PF01904 Protein of unknown function DUF72 17 264 5.0E-59 T 14-10-2018 IPR002763 Protein of unknown function DUF72 C2I25_27950 a20282646b4f47e7bfd7f28f9a1b13b5 186 Gene3D G3DSA:1.10.260.40 1 71 9.9E-18 T 14-10-2018 C2I25_27950 a20282646b4f47e7bfd7f28f9a1b13b5 186 Pfam PF07883 Cupin domain 110 180 1.1E-15 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_27950 a20282646b4f47e7bfd7f28f9a1b13b5 186 SUPERFAMILY SSF51182 57 184 4.8E-24 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_27950 a20282646b4f47e7bfd7f28f9a1b13b5 186 Pfam PF01381 Helix-turn-helix 13 61 1.3E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_27950 a20282646b4f47e7bfd7f28f9a1b13b5 186 Gene3D G3DSA:2.60.120.10 73 184 9.3E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_27950 a20282646b4f47e7bfd7f28f9a1b13b5 186 SUPERFAMILY SSF47413 2 69 2.31E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_27950 a20282646b4f47e7bfd7f28f9a1b13b5 186 SMART SM00530 9 64 2.5E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_02045 b3f68aa899329d30f1e853638d5f9a02 549 Gene3D G3DSA:2.60.40.1220 30 132 4.7E-22 T 14-10-2018 C2I25_02045 b3f68aa899329d30f1e853638d5f9a02 549 Pfam PF13115 YtkA-like 448 529 2.0E-12 T 14-10-2018 IPR032693 YtkA-like domain C2I25_02045 b3f68aa899329d30f1e853638d5f9a02 549 SUPERFAMILY SSF81296 29 127 1.82E-19 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_02045 b3f68aa899329d30f1e853638d5f9a02 549 Pfam PF04234 CopC domain 30 127 3.3E-19 T 14-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 C2I25_02045 b3f68aa899329d30f1e853638d5f9a02 549 Pfam PF05425 Copper resistance protein D 336 426 1.5E-16 T 14-10-2018 IPR008457 Copper resistance protein D GO:0016021 C2I25_24435 47a2270e076772f9bed901182a17b6ef 168 Pfam PF13042 Protein of unknown function (DUF3902) 2 162 5.8E-99 T 14-10-2018 IPR025001 Protein of unknown function DUF3902 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 148 159 - T 14-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 Pfam PF00082 Subtilase family 144 443 2.0E-44 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 199 209 - T 14-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 PIRSF PIRSF037875 1 471 1.6E-127 T 14-10-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 Gene3D G3DSA:3.40.50.200 112 471 6.0E-92 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 SUPERFAMILY SSF52743 137 470 1.96E-61 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 PRINTS PR01779 Lantibiotic leader peptide processing protein signature 276 291 2.5E-12 T 14-10-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 PRINTS PR01779 Lantibiotic leader peptide processing protein signature 120 132 2.5E-12 T 14-10-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 PRINTS PR01779 Lantibiotic leader peptide processing protein signature 218 233 2.5E-12 T 14-10-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 PRINTS PR01779 Lantibiotic leader peptide processing protein signature 381 395 2.5E-12 T 14-10-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 208 2.3E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 PRINTS PR00723 Subtilisin serine protease family (S8) signature 410 426 2.3E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 PRINTS PR00723 Subtilisin serine protease family (S8) signature 143 162 2.3E-15 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I25_21410 8c4cea51654a4b116f1c11c6cb6de76f 471 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 411 421 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I25_12215 13283da4a30eba26d368cb49fd0a85da 142 PIRSF PIRSF038931 1 141 1.2E-43 T 14-10-2018 IPR014099 Spore coat protein GerQ C2I25_12215 13283da4a30eba26d368cb49fd0a85da 142 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 53 130 2.9E-35 T 14-10-2018 IPR014099 Spore coat protein GerQ C2I25_12215 13283da4a30eba26d368cb49fd0a85da 142 Pfam PF09671 Spore coat protein (Spore_GerQ) 56 130 6.9E-36 T 14-10-2018 IPR014099 Spore coat protein GerQ C2I25_19300 21a1c50b9c92a681a2f4847eeeffdf4b 259 SUPERFAMILY SSF56317 1 258 8.63E-77 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I25_19300 21a1c50b9c92a681a2f4847eeeffdf4b 259 Gene3D G3DSA:3.60.110.10 1 259 1.7E-93 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I25_19300 21a1c50b9c92a681a2f4847eeeffdf4b 259 Pfam PF00795 Carbon-nitrogen hydrolase 2 245 1.8E-51 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 C2I25_28145 66b7cfcef33bf2a48318a50a4da3d926 74 SMART SM00923 3 53 5.1E-29 T 14-10-2018 IPR005153 MbtH-like domain C2I25_28145 66b7cfcef33bf2a48318a50a4da3d926 74 SUPERFAMILY SSF160582 1 64 1.44E-27 T 14-10-2018 IPR038020 MbtH-like domain superfamily C2I25_28145 66b7cfcef33bf2a48318a50a4da3d926 74 Gene3D G3DSA:3.90.820.10 1 68 7.5E-29 T 14-10-2018 C2I25_28145 66b7cfcef33bf2a48318a50a4da3d926 74 Pfam PF03621 MbtH-like protein 1 52 1.2E-26 T 14-10-2018 IPR005153 MbtH-like domain C2I25_18655 0841be103bc34eb2288dd366f336b2bd 240 SMART SM00382 26 213 1.7E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_18655 0841be103bc34eb2288dd366f336b2bd 240 Gene3D G3DSA:3.40.50.300 1 240 1.4E-80 T 14-10-2018 C2I25_18655 0841be103bc34eb2288dd366f336b2bd 240 Pfam PF00005 ABC transporter 17 165 2.8E-39 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_18655 0841be103bc34eb2288dd366f336b2bd 240 PIRSF PIRSF039085 1 240 2.3E-115 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 C2I25_18655 0841be103bc34eb2288dd366f336b2bd 240 SUPERFAMILY SSF52540 1 235 1.3E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18655 0841be103bc34eb2288dd366f336b2bd 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_12950 5512524bb9d31347c9e4a6a0ce675854 71 Pfam PF11148 Protein of unknown function (DUF2922) 3 66 1.5E-16 T 14-10-2018 IPR021321 Protein of unknown function DUF2922 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 3 508 2.2E-211 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 3 509 49.815 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 SUPERFAMILY SSF64158 76 309 1.83E-92 T 14-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 81 298 9.1E-85 T 14-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 PIRSF PIRSF001492 1 509 3.0E-205 T 14-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 SUPERFAMILY SSF53649 2 508 8.73E-76 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 Gene3D G3DSA:3.40.720.10 4 506 2.0E-237 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 Gene3D G3DSA:3.40.1450.10 76 311 2.0E-237 T 14-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I25_13545 9a2e220805fde27577e83fa32eb55341 509 Pfam PF01676 Metalloenzyme superfamily 3 497 6.2E-77 T 14-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 C2I25_09620 a6fe2c87a8580ea4537718255b68483a 213 SMART SM01007 8 184 2.3E-59 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I25_09620 a6fe2c87a8580ea4537718255b68483a 213 SUPERFAMILY SSF53639 2 212 1.08E-62 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I25_09620 a6fe2c87a8580ea4537718255b68483a 213 Gene3D G3DSA:3.40.225.10 1 213 5.6E-75 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I25_09620 a6fe2c87a8580ea4537718255b68483a 213 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 184 6.9E-44 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I25_00980 5c42b4565dd99f38f2641849cb056303 236 Gene3D G3DSA:3.40.50.1400 1 122 3.1E-27 T 14-10-2018 C2I25_00980 5c42b4565dd99f38f2641849cb056303 236 Gene3D G3DSA:3.40.50.1400 123 234 4.1E-11 T 14-10-2018 C2I25_00980 5c42b4565dd99f38f2641849cb056303 236 Pfam PF01903 CbiX 132 208 5.8E-10 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 C2I25_00980 5c42b4565dd99f38f2641849cb056303 236 Pfam PF01903 CbiX 9 113 6.9E-29 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 C2I25_00980 5c42b4565dd99f38f2641849cb056303 236 SUPERFAMILY SSF53800 1 234 1.74E-47 T 14-10-2018 C2I25_12180 ede4877c7a1b36700f0b9e7a457c275c 225 SUPERFAMILY SSF52141 3 221 1.11E-92 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_12180 ede4877c7a1b36700f0b9e7a457c275c 225 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 214 1.5E-81 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_12180 ede4877c7a1b36700f0b9e7a457c275c 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 41.1 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_12180 ede4877c7a1b36700f0b9e7a457c275c 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 14-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_12180 ede4877c7a1b36700f0b9e7a457c275c 225 SMART SM00987 50 210 2.9E-36 T 14-10-2018 C2I25_12180 ede4877c7a1b36700f0b9e7a457c275c 225 SMART SM00986 50 210 2.9E-36 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_12180 ede4877c7a1b36700f0b9e7a457c275c 225 Gene3D G3DSA:3.40.470.10 1 225 5.2E-99 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_12180 ede4877c7a1b36700f0b9e7a457c275c 225 Pfam PF03167 Uracil DNA glycosylase superfamily 54 209 1.8E-26 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 Pfam PF03466 LysR substrate binding domain 88 286 5.7E-36 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 Gene3D G3DSA:1.10.10.10 1 89 2.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 Gene3D G3DSA:3.40.190.290 90 288 1.5E-32 T 14-10-2018 C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 SUPERFAMILY SSF46785 1 109 5.29E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 SUPERFAMILY SSF53850 85 286 8.89E-34 T 14-10-2018 C2I25_27890 a2228c0e4ec90629030b83a358a388a2 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 8.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_28055 b063be999c875df5e78a1a07d659d93c 337 Gene3D G3DSA:1.10.3720.10 71 302 2.0E-17 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_28055 b063be999c875df5e78a1a07d659d93c 337 SUPERFAMILY SSF161098 78 285 1.64E-13 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_28055 b063be999c875df5e78a1a07d659d93c 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 301 1.6E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_15875 a62dbb1a6f482df59e2f7384c13a2780 40 Gene3D G3DSA:1.20.59.10 2 40 2.2E-10 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I25_15875 a62dbb1a6f482df59e2f7384c13a2780 40 SUPERFAMILY SSF48600 4 38 8.24E-10 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I25_15875 a62dbb1a6f482df59e2f7384c13a2780 40 Pfam PF01817 Chorismate mutase type II 10 39 1.3E-8 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I25_25340 2eeea06be55cf9e5ff28b3245753c4c1 333 Gene3D G3DSA:2.30.30.40 23 139 1.6E-46 T 14-10-2018 C2I25_25340 2eeea06be55cf9e5ff28b3245753c4c1 333 Gene3D G3DSA:3.90.1720.10 209 333 7.8E-41 T 14-10-2018 C2I25_25340 2eeea06be55cf9e5ff28b3245753c4c1 333 Pfam PF00877 NlpC/P60 family 223 330 2.6E-26 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I25_25340 2eeea06be55cf9e5ff28b3245753c4c1 333 SUPERFAMILY SSF54001 206 332 2.55E-40 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I25_25340 2eeea06be55cf9e5ff28b3245753c4c1 333 Gene3D G3DSA:2.30.30.40 140 207 1.9E-36 T 14-10-2018 C2I25_04555 8330891e5084eaa0da1f70cecd06d89f 63 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 21 63 8.8E-20 T 14-10-2018 IPR021008 Protein of unknown function DUF3687 C2I25_11020 b4b3108cbd342744f8bc43bed3d7ae06 199 Pfam PF05175 Methyltransferase small domain 28 195 7.9E-53 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 C2I25_11020 b4b3108cbd342744f8bc43bed3d7ae06 199 SUPERFAMILY SSF53335 12 197 1.82E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_11020 b4b3108cbd342744f8bc43bed3d7ae06 199 Gene3D G3DSA:3.40.50.150 6 199 2.0E-49 T 14-10-2018 C2I25_14630 2bb81f5876fb4f74a04baa911d0676b2 168 SUPERFAMILY SSF54909 68 149 2.01E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_14630 2bb81f5876fb4f74a04baa911d0676b2 168 Gene3D G3DSA:1.10.10.10 4 55 9.6E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_14630 2bb81f5876fb4f74a04baa911d0676b2 168 Gene3D G3DSA:3.30.70.920 58 155 4.9E-19 T 14-10-2018 C2I25_14630 2bb81f5876fb4f74a04baa911d0676b2 168 Pfam PF01037 Lrp/AsnC ligand binding domain 73 146 5.2E-13 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I25_14630 2bb81f5876fb4f74a04baa911d0676b2 168 SMART SM00344 7 118 0.0077 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I25_14630 2bb81f5876fb4f74a04baa911d0676b2 168 SUPERFAMILY SSF46785 7 62 2.64E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_21415 5d0ead93b02b2a45a4c4d933f5ed3d44 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 520 3.2E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_21415 5d0ead93b02b2a45a4c4d933f5ed3d44 537 Pfam PF00501 AMP-binding enzyme 23 436 1.2E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_21415 5d0ead93b02b2a45a4c4d933f5ed3d44 537 SUPERFAMILY SSF56801 7 532 1.83E-133 T 14-10-2018 C2I25_21415 5d0ead93b02b2a45a4c4d933f5ed3d44 537 Gene3D G3DSA:3.40.50.12780 1 431 4.9E-120 T 14-10-2018 C2I25_21415 5d0ead93b02b2a45a4c4d933f5ed3d44 537 Gene3D G3DSA:3.30.300.310 432 535 1.7E-33 T 14-10-2018 C2I25_00255 e2b8a3dcc16e0fa060cd5c023cd00798 239 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 59 185 4.2E-38 T 14-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 C2I25_00255 e2b8a3dcc16e0fa060cd5c023cd00798 239 SMART SM00563 74 188 3.2E-38 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I25_00255 e2b8a3dcc16e0fa060cd5c023cd00798 239 SUPERFAMILY SSF69593 46 237 9.81E-53 T 14-10-2018 C2I25_00255 e2b8a3dcc16e0fa060cd5c023cd00798 239 Pfam PF01553 Acyltransferase 60 184 6.5E-33 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 SUPERFAMILY SSF103473 9 404 1.06E-71 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 PRINTS PR01035 Tetracycline resistance protein signature 286 307 8.4E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 PRINTS PR01035 Tetracycline resistance protein signature 29 45 8.4E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 PRINTS PR01035 Tetracycline resistance protein signature 173 193 8.4E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 PRINTS PR01035 Tetracycline resistance protein signature 113 134 8.4E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 PRINTS PR01035 Tetracycline resistance protein signature 86 110 8.4E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 Gene3D G3DSA:1.20.1720.10 19 398 2.5E-107 T 14-10-2018 C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 Pfam PF07690 Major Facilitator Superfamily 26 365 1.4E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_10595 960250e33915aaf4cf8535df0a6e8e2d 416 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 17 398 2.2E-108 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 C2I25_06575 c29da4cf87af0e4ce7646d91f63f18da 36 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 11 33 1.6E-12 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_06575 c29da4cf87af0e4ce7646d91f63f18da 36 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 12 35 4.1E-11 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_27430 4ac5504e9700ff4de99746b625cb1cee 382 Pfam PF01757 Acyltransferase family 19 359 1.4E-36 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I25_19305 5f71a1caaeae2def0c16378d3e2cc98e 393 PIRSF PIRSF031134 1 388 6.4E-157 T 14-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I25_19305 5f71a1caaeae2def0c16378d3e2cc98e 393 Gene3D G3DSA:3.90.1200.10 112 388 2.5E-104 T 14-10-2018 C2I25_19305 5f71a1caaeae2def0c16378d3e2cc98e 393 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 393 183.955 T 14-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I25_19305 5f71a1caaeae2def0c16378d3e2cc98e 393 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 31 384 1.0E-135 T 14-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I25_19305 5f71a1caaeae2def0c16378d3e2cc98e 393 Gene3D G3DSA:3.30.200.20 1 111 8.8E-41 T 14-10-2018 C2I25_19305 5f71a1caaeae2def0c16378d3e2cc98e 393 Pfam PF01636 Phosphotransferase enzyme family 29 261 3.6E-11 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_19305 5f71a1caaeae2def0c16378d3e2cc98e 393 SUPERFAMILY SSF56112 3 369 1.24E-85 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_18005 7e9395868e745f24bb74afd47ebd63a3 387 SUPERFAMILY SSF53383 16 379 2.11E-108 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_18005 7e9395868e745f24bb74afd47ebd63a3 387 PIRSF PIRSF001434 2 382 2.8E-141 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_18005 7e9395868e745f24bb74afd47ebd63a3 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 378 1.2E-145 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_18005 7e9395868e745f24bb74afd47ebd63a3 387 Gene3D G3DSA:3.40.640.10 4 246 5.5E-89 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_18005 7e9395868e745f24bb74afd47ebd63a3 387 Gene3D G3DSA:3.90.1150.10 247 381 1.7E-43 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_18005 7e9395868e745f24bb74afd47ebd63a3 387 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_13780 79804138d70e862188e337421761752e 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 7.2E-57 T 14-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I25_13780 79804138d70e862188e337421761752e 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 5.9E-20 T 14-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I25_13780 79804138d70e862188e337421761752e 393 Pfam PF07670 Nucleoside recognition 91 189 1.2E-5 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I25_11850 31a48373ca7e05ecc3636a5c5444ca76 186 Pfam PF08876 Domain of unknown function (DUF1836) 19 123 1.4E-31 T 14-10-2018 IPR014975 Protein of unknown function DUF1836 C2I25_24915 2b965ba2949b14b52ad086d00b0c3a86 312 Pfam PF13536 Putative multidrug resistance efflux transporter 38 297 1.1E-106 T 14-10-2018 IPR032713 Putative multidrug resistance efflux transporter C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 SUPERFAMILY SSF53474 2 268 2.59E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 Pfam PF00561 alpha/beta hydrolase fold 24 251 8.0E-26 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 PRINTS PR00412 Epoxide hydrolase signature 49 64 3.7E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 PRINTS PR00412 Epoxide hydrolase signature 211 227 3.7E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 PRINTS PR00412 Epoxide hydrolase signature 244 266 3.7E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 PRINTS PR00412 Epoxide hydrolase signature 29 47 3.7E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 Gene3D G3DSA:3.40.50.1820 1 268 4.3E-64 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 6.8E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 6.8E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_15330 f176e84d474b57bd5a8ad9346def0e6b 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 6.8E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_01240 9a272f148edab7a1a5e650234fa1d81d 295 Gene3D G3DSA:3.40.630.30 125 293 2.0E-25 T 14-10-2018 C2I25_01240 9a272f148edab7a1a5e650234fa1d81d 295 Pfam PF00583 Acetyltransferase (GNAT) family 193 275 2.1E-15 T 14-10-2018 IPR000182 GNAT domain C2I25_01240 9a272f148edab7a1a5e650234fa1d81d 295 Pfam PF00583 Acetyltransferase (GNAT) family 30 109 9.2E-5 T 14-10-2018 IPR000182 GNAT domain C2I25_01240 9a272f148edab7a1a5e650234fa1d81d 295 SUPERFAMILY SSF55729 3 284 4.45E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01240 9a272f148edab7a1a5e650234fa1d81d 295 Gene3D G3DSA:3.40.630.30 2 124 2.7E-9 T 14-10-2018 C2I25_26305 ccf4f5bd7c2ee6c4970fbd83ee1d9b2f 410 Gene3D G3DSA:1.20.1250.20 8 394 6.5E-35 T 14-10-2018 C2I25_26305 ccf4f5bd7c2ee6c4970fbd83ee1d9b2f 410 Pfam PF07690 Major Facilitator Superfamily 16 359 4.6E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_26305 ccf4f5bd7c2ee6c4970fbd83ee1d9b2f 410 SUPERFAMILY SSF103473 1 395 1.02E-43 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_26305 ccf4f5bd7c2ee6c4970fbd83ee1d9b2f 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 164 181 5.0E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_26305 ccf4f5bd7c2ee6c4970fbd83ee1d9b2f 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 13 35 5.0E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_26305 ccf4f5bd7c2ee6c4970fbd83ee1d9b2f 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 76 94 5.0E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_26305 ccf4f5bd7c2ee6c4970fbd83ee1d9b2f 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 299 322 5.0E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_26305 ccf4f5bd7c2ee6c4970fbd83ee1d9b2f 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 361 384 5.0E-6 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_19655 abc9549b0e3ad76e7e34b13c563951e3 130 Gene3D G3DSA:1.20.5.850 7 49 1.6E-10 T 14-10-2018 C2I25_19655 abc9549b0e3ad76e7e34b13c563951e3 130 Gene3D G3DSA:3.30.310.120 50 129 1.6E-30 T 14-10-2018 C2I25_19655 abc9549b0e3ad76e7e34b13c563951e3 130 SUPERFAMILY SSF111171 4 128 1.44E-65 T 14-10-2018 IPR036294 Rbstp2229-like superfamily C2I25_19655 abc9549b0e3ad76e7e34b13c563951e3 130 Pfam PF08968 Domain of unknown function (DUF1885) 2 129 1.2E-57 T 14-10-2018 IPR015062 Protein of unknown function DUF1885 C2I25_00900 e24df41e0475e1f8f7a1593556220fdf 172 Pfam PF06114 IrrE N-terminal-like domain 37 148 5.6E-11 T 14-10-2018 IPR010359 IrrE N-terminal-like domain C2I25_05265 dee7105e08618e5d1df02959b648b8d5 140 Pfam PF13673 Acetyltransferase (GNAT) domain 21 140 1.2E-21 T 14-10-2018 IPR000182 GNAT domain C2I25_05265 dee7105e08618e5d1df02959b648b8d5 140 Gene3D G3DSA:3.40.630.30 2 139 2.0E-43 T 14-10-2018 C2I25_05265 dee7105e08618e5d1df02959b648b8d5 140 SUPERFAMILY SSF55729 4 140 3.09E-37 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_12520 bc6e614284f823f90c482bb133cf98f4 195 Gene3D G3DSA:3.40.50.300 1 141 4.7E-64 T 14-10-2018 C2I25_12520 bc6e614284f823f90c482bb133cf98f4 195 SUPERFAMILY SSF57716 142 192 7.13E-16 T 14-10-2018 C2I25_12520 bc6e614284f823f90c482bb133cf98f4 195 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 14-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 C2I25_12520 bc6e614284f823f90c482bb133cf98f4 195 Gene3D G3DSA:3.30.60.20 142 195 1.3E-26 T 14-10-2018 C2I25_12520 bc6e614284f823f90c482bb133cf98f4 195 PIRSF PIRSF035805 5 195 1.7E-68 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 C2I25_12520 bc6e614284f823f90c482bb133cf98f4 195 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 38.865 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 C2I25_12520 bc6e614284f823f90c482bb133cf98f4 195 Pfam PF00265 Thymidine kinase 8 187 5.5E-61 T 14-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 C2I25_12520 bc6e614284f823f90c482bb133cf98f4 195 SUPERFAMILY SSF52540 8 142 1.24E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24310 6d16b09d428aeac6e5843dbf308219da 300 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 1.1E-38 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 238 4.5E-14 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 Gene3D G3DSA:1.10.3120.10 115 424 6.7E-98 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 Hamap MF_00303 Trigger factor [tig]. 1 425 23.972 T 14-10-2018 IPR005215 Trigger factor GO:0015031 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 Gene3D G3DSA:3.10.50.40 151 248 6.7E-98 T 14-10-2018 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 Gene3D G3DSA:3.30.70.1050 3 114 2.4E-29 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 SUPERFAMILY SSF54534 89 243 8.64E-38 T 14-10-2018 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 2.9E-43 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 TIGRFAM TIGR00115 tig: trigger factor 14 421 9.0E-145 T 14-10-2018 IPR005215 Trigger factor GO:0015031 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 PIRSF PIRSF003095 1 425 7.7E-141 T 14-10-2018 IPR005215 Trigger factor GO:0015031 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 3.7E-49 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 SUPERFAMILY SSF102735 1 128 2.49E-38 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 C2I25_16915 3a12727b7efe5545f2a78ab54749cece 425 SUPERFAMILY SSF109998 250 424 1.57E-45 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I25_14410 7263b0eff0c9e4f454c036709780b78a 113 Pfam PF03831 PhnA domain 46 113 1.0E-33 T 14-10-2018 IPR013988 PhnA protein, C-terminal C2I25_14410 7263b0eff0c9e4f454c036709780b78a 113 Gene3D G3DSA:2.30.30.40 43 113 5.2E-35 T 14-10-2018 C2I25_14410 7263b0eff0c9e4f454c036709780b78a 113 Pfam PF08274 PhnA Zinc-Ribbon 3 31 3.0E-17 T 14-10-2018 IPR013987 PhnA protein, N-terminal C2I25_14410 7263b0eff0c9e4f454c036709780b78a 113 Gene3D G3DSA:2.20.25.10 1 42 5.5E-21 T 14-10-2018 C2I25_14410 7263b0eff0c9e4f454c036709780b78a 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 113 2.0E-51 T 14-10-2018 IPR004624 PhnA protein C2I25_14410 7263b0eff0c9e4f454c036709780b78a 113 SUPERFAMILY SSF82057 41 113 1.05E-28 T 14-10-2018 C2I25_14410 7263b0eff0c9e4f454c036709780b78a 113 SUPERFAMILY SSF57783 3 37 7.99E-15 T 14-10-2018 C2I25_08315 4041c0454e56df8d2f8215904efc0972 500 PIRSF PIRSF005690 11 491 1.3E-168 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_08315 4041c0454e56df8d2f8215904efc0972 500 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 26 476 1.7E-171 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_22785 87d6d87b078b77750409dac73f163182 587 SUPERFAMILY SSF52091 438 544 6.28E-19 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_22785 87d6d87b078b77750409dac73f163182 587 Pfam PF01740 STAS domain 441 541 5.8E-20 T 14-10-2018 IPR002645 STAS domain C2I25_22785 87d6d87b078b77750409dac73f163182 587 Gene3D G3DSA:3.30.750.24 426 552 4.7E-28 T 14-10-2018 IPR036513 STAS domain superfamily C2I25_22785 87d6d87b078b77750409dac73f163182 587 Pfam PF00916 Sulfate permease family 17 381 2.0E-93 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I25_22785 87d6d87b078b77750409dac73f163182 587 TIGRFAM TIGR00815 sulP: sulfate permease 9 540 7.0E-120 T 14-10-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 C2I25_02730 8ba7107a6d77515b9504844d4023bc46 137 Pfam PF03965 Penicillinase repressor 18 132 5.9E-28 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 C2I25_02730 8ba7107a6d77515b9504844d4023bc46 137 PIRSF PIRSF019455 13 137 1.7E-21 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 C2I25_02730 8ba7107a6d77515b9504844d4023bc46 137 Gene3D G3DSA:1.10.10.10 14 81 2.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_02730 8ba7107a6d77515b9504844d4023bc46 137 SUPERFAMILY SSF46785 17 134 1.59E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08955 9b15c3253c05d27e695f2e80cf0ac9c8 362 Pfam PF06081 Aromatic acid exporter family member 1 1 142 4.2E-45 T 14-10-2018 IPR010343 Aromatic acid exporter family member 1 C2I25_11975 343de73fd69494461e33fb2183a0c9c9 246 Pfam PF00072 Response regulator receiver domain 4 113 7.3E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_11975 343de73fd69494461e33fb2183a0c9c9 246 Gene3D G3DSA:3.40.50.2300 1 132 1.6E-32 T 14-10-2018 C2I25_11975 343de73fd69494461e33fb2183a0c9c9 246 SMART SM00850 148 245 2.1E-37 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_11975 343de73fd69494461e33fb2183a0c9c9 246 SMART SM00448 2 113 2.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_11975 343de73fd69494461e33fb2183a0c9c9 246 Pfam PF04397 LytTr DNA-binding domain 149 244 6.0E-32 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_11975 343de73fd69494461e33fb2183a0c9c9 246 SUPERFAMILY SSF52172 2 131 1.99E-30 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_11975 343de73fd69494461e33fb2183a0c9c9 246 Gene3D G3DSA:2.20.25.10 209 246 3.4E-10 T 14-10-2018 C2I25_11975 343de73fd69494461e33fb2183a0c9c9 246 Gene3D G3DSA:2.40.50.40 139 208 3.9E-16 T 14-10-2018 C2I25_24965 f2b8bb32e541106804814bd731ae5758 328 Gene3D G3DSA:3.40.190.10 115 214 2.4E-94 T 14-10-2018 C2I25_24965 f2b8bb32e541106804814bd731ae5758 328 Gene3D G3DSA:3.40.190.10 35 311 2.4E-94 T 14-10-2018 C2I25_24965 f2b8bb32e541106804814bd731ae5758 328 SMART SM00062 34 256 1.7E-25 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_24965 f2b8bb32e541106804814bd731ae5758 328 SUPERFAMILY SSF53850 32 258 1.37E-51 T 14-10-2018 C2I25_24965 f2b8bb32e541106804814bd731ae5758 328 Pfam PF09084 NMT1/THI5 like 44 248 1.4E-28 T 14-10-2018 IPR015168 SsuA/THI5-like C2I25_24965 f2b8bb32e541106804814bd731ae5758 328 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 35 321 2.2E-92 T 14-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 C2I25_24965 f2b8bb32e541106804814bd731ae5758 328 Gene3D G3DSA:1.10.8.450 247 280 2.4E-94 T 14-10-2018 C2I25_20350 a3ab650de08267872d7aab0c3a66b9dc 434 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 5 431 4.5E-235 T 14-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 C2I25_20350 a3ab650de08267872d7aab0c3a66b9dc 434 Gene3D G3DSA:3.50.50.60 3 178 5.9E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_20350 a3ab650de08267872d7aab0c3a66b9dc 434 Gene3D G3DSA:3.50.50.60 290 434 4.5E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_20350 a3ab650de08267872d7aab0c3a66b9dc 434 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 434 37.162 T 14-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 C2I25_20350 a3ab650de08267872d7aab0c3a66b9dc 434 SUPERFAMILY SSF51905 7 367 7.13E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_20350 a3ab650de08267872d7aab0c3a66b9dc 434 Pfam PF01134 Glucose inhibited division protein A 6 368 1.8E-116 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 C2I25_20350 a3ab650de08267872d7aab0c3a66b9dc 434 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 C2I25_06935 b6487a19768e91e27130c2c931ee3bd4 620 Pfam PF00395 S-layer homology domain 30 69 1.0E-7 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06935 b6487a19768e91e27130c2c931ee3bd4 620 Pfam PF00395 S-layer homology domain 147 187 3.4E-7 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06935 b6487a19768e91e27130c2c931ee3bd4 620 Pfam PF00395 S-layer homology domain 84 126 2.9E-9 T 14-10-2018 IPR001119 S-layer homology domain C2I25_06935 b6487a19768e91e27130c2c931ee3bd4 620 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 425 539 7.4E-16 T 14-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 C2I25_06935 b6487a19768e91e27130c2c931ee3bd4 620 Gene3D G3DSA:1.10.530.10 421 542 1.4E-16 T 14-10-2018 C2I25_06935 b6487a19768e91e27130c2c931ee3bd4 620 SMART SM00047 411 549 1.4E-4 T 14-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 C2I25_20840 e859e95051020013c8fc9201eac8b312 335 Gene3D G3DSA:1.10.3470.10 5 333 2.6E-85 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_20840 e859e95051020013c8fc9201eac8b312 335 SUPERFAMILY SSF81345 7 327 8.37E-78 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_20840 e859e95051020013c8fc9201eac8b312 335 Pfam PF01032 FecCD transport family 18 327 1.4E-83 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_15690 8757d9b246ccb5a97f9795b357ddca68 75 Pfam PF13119 Domain of unknown function (DUF3973) 1 40 1.7E-29 T 14-10-2018 IPR025003 Domain of unknown function DUF3973 C2I25_02940 9619daac79f6f0600e9fa52f287f67e0 422 Pfam PF07690 Major Facilitator Superfamily 24 377 4.8E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_02940 9619daac79f6f0600e9fa52f287f67e0 422 Gene3D G3DSA:1.20.1250.20 12 410 1.0E-41 T 14-10-2018 C2I25_02940 9619daac79f6f0600e9fa52f287f67e0 422 SUPERFAMILY SSF103473 18 409 2.62E-44 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_26675 4fb182ad9bbe544f3f622fffd65f7f38 199 SMART SM00014 61 166 1.1E-20 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_26675 4fb182ad9bbe544f3f622fffd65f7f38 199 Pfam PF01569 PAP2 superfamily 96 171 7.2E-18 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I25_26675 4fb182ad9bbe544f3f622fffd65f7f38 199 Gene3D G3DSA:1.20.144.10 4 197 2.9E-21 T 14-10-2018 C2I25_26675 4fb182ad9bbe544f3f622fffd65f7f38 199 SUPERFAMILY SSF48317 3 169 9.16E-38 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I25_15370 858a51ecf4410b79c55add34222f8423 338 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 159 294 1.5E-53 T 14-10-2018 IPR021759 Domain of unknown function DUF3324, C-terminal C2I25_15370 858a51ecf4410b79c55add34222f8423 338 Pfam PF06030 Bacterial protein of unknown function (DUF916) 29 148 1.3E-42 T 14-10-2018 IPR010317 Protein of unknown function DUF916, cell surface putative C2I25_14820 b54b4a24bf9b52e23ba78d62d61a1ef6 201 Pfam PF12389 Camelysin metallo-endopeptidase 2 199 1.2E-82 T 14-10-2018 IPR022121 Peptidase M73, camelysin C2I25_14820 b54b4a24bf9b52e23ba78d62d61a1ef6 201 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 12 44 1.9E-10 T 14-10-2018 IPR023833 Signal peptide, camelysin C2I25_13170 1006e889e52d1bbba8a59d7c07f3febd 123 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 5 115 9.6E-43 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I25_13170 1006e889e52d1bbba8a59d7c07f3febd 123 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 3 119 29.754 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I25_13170 1006e889e52d1bbba8a59d7c07f3febd 123 Gene3D G3DSA:3.30.360.110 3 64 5.8E-19 T 14-10-2018 C2I25_13170 1006e889e52d1bbba8a59d7c07f3febd 123 Gene3D G3DSA:3.30.160.750 65 122 1.7E-20 T 14-10-2018 C2I25_13170 1006e889e52d1bbba8a59d7c07f3febd 123 SUPERFAMILY SSF56276 5 117 9.61E-40 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 C2I25_13170 1006e889e52d1bbba8a59d7c07f3febd 123 Pfam PF02675 S-adenosylmethionine decarboxylase 9 115 6.2E-35 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I25_07030 6e776ac4163b8396491739a8f38e3d46 381 Pfam PF04286 Protein of unknown function (DUF445) 17 379 1.8E-83 T 14-10-2018 IPR007383 Protein of unknown function DUF445 C2I25_07030 6e776ac4163b8396491739a8f38e3d46 381 PIRSF PIRSF032178 4 381 8.3E-138 T 14-10-2018 IPR016991 Protein of unknown function UCP032178 C2I25_18420 a610ee4d26ed2a23d762bbc63ceb222c 452 Pfam PF13742 OB-fold nucleic acid binding domain 6 101 6.1E-33 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 C2I25_18420 a610ee4d26ed2a23d762bbc63ceb222c 452 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 7 353 8.0E-141 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 C2I25_18420 a610ee4d26ed2a23d762bbc63ceb222c 452 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 441 30.252 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 C2I25_18420 a610ee4d26ed2a23d762bbc63ceb222c 452 Pfam PF02601 Exonuclease VII, large subunit 124 438 4.7E-99 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 C2I25_07295 90fccedb01685c597bf4f696fb34bdd5 119 SUPERFAMILY SSF54593 7 117 8.88E-12 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_07295 90fccedb01685c597bf4f696fb34bdd5 119 Gene3D G3DSA:3.10.180.10 5 119 1.2E-11 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_15795 9ca4eb69e28b71650d9806959c1bc444 204 Gene3D G3DSA:2.40.50.140 8 202 2.5E-75 T 14-10-2018 C2I25_15795 9ca4eb69e28b71650d9806959c1bc444 204 Pfam PF14794 Domain of unknown function (DUF4479) 27 94 1.2E-24 T 14-10-2018 IPR027855 Domain of unknown function DUF4479 C2I25_15795 9ca4eb69e28b71650d9806959c1bc444 204 Pfam PF01588 Putative tRNA binding domain 99 200 1.6E-27 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 C2I25_15795 9ca4eb69e28b71650d9806959c1bc444 204 Gene3D G3DSA:3.30.1940.10 21 95 2.5E-75 T 14-10-2018 IPR037154 YtpR-like superfamily C2I25_15795 9ca4eb69e28b71650d9806959c1bc444 204 SUPERFAMILY SSF50249 95 203 2.94E-33 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_24475 f8457be8f5ea7088ba22dfb3f70c05a6 370 Pfam PF13210 Domain of unknown function (DUF4018) 48 240 3.2E-102 T 14-10-2018 IPR025089 Protein of unknown function DUF4018 C2I25_08770 3ddd6e2c8aea399c0902635601d0a3fe 295 Pfam PF12671 Putative amidase domain 136 289 8.9E-37 T 14-10-2018 IPR024301 Putative amidase domain C2I25_07640 f43cc9ccfa1cb3eb984439ca75ac9bde 153 SUPERFAMILY SSF46785 23 151 3.62E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_07640 f43cc9ccfa1cb3eb984439ca75ac9bde 153 SMART SM00347 34 137 7.3E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_07640 f43cc9ccfa1cb3eb984439ca75ac9bde 153 Pfam PF01047 MarR family 42 98 1.4E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_07640 f43cc9ccfa1cb3eb984439ca75ac9bde 153 Gene3D G3DSA:1.10.10.10 1 152 4.4E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04200 d49fab09fc067583285693981c91ef9a 451 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 419 1.6E-142 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_04200 d49fab09fc067583285693981c91ef9a 451 Pfam PF05525 Branched-chain amino acid transport protein 6 432 2.5E-157 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_04025 085becf94889d56ada90d04e433d5176 385 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 42 385 5.5E-77 T 14-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 C2I25_04025 085becf94889d56ada90d04e433d5176 385 Pfam PF01578 Cytochrome C assembly protein 77 173 8.5E-9 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 C2I25_04025 085becf94889d56ada90d04e433d5176 385 Pfam PF01578 Cytochrome C assembly protein 255 382 2.4E-26 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 C2I25_25165 e5c4ee3cf38ed1f4d7093e7ae5fafc60 579 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 180 499 1.5E-36 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_25165 e5c4ee3cf38ed1f4d7093e7ae5fafc60 579 SUPERFAMILY SSF53850 134 578 3.26E-72 T 14-10-2018 C2I25_25165 e5c4ee3cf38ed1f4d7093e7ae5fafc60 579 Gene3D G3DSA:3.40.190.10 126 354 8.8E-41 T 14-10-2018 C2I25_25165 e5c4ee3cf38ed1f4d7093e7ae5fafc60 579 Gene3D G3DSA:3.10.105.10 355 548 1.1E-13 T 14-10-2018 C2I25_25165 e5c4ee3cf38ed1f4d7093e7ae5fafc60 579 Pfam PF12793 Sugar transport-related sRNA regulator N-term 5 95 5.3E-21 T 14-10-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain C2I25_25165 e5c4ee3cf38ed1f4d7093e7ae5fafc60 579 PIRSF PIRSF002741 127 579 5.6E-44 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_25685 7ee81fb4f84a7ece3766d447a702b08b 164 Pfam PF04229 GrpB protein 9 160 2.0E-41 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase C2I25_25685 7ee81fb4f84a7ece3766d447a702b08b 164 Gene3D G3DSA:3.30.460.10 6 164 6.0E-42 T 14-10-2018 C2I25_25685 7ee81fb4f84a7ece3766d447a702b08b 164 SUPERFAMILY SSF81301 10 162 1.18E-39 T 14-10-2018 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 SUPERFAMILY SSF48019 244 360 7.48E-29 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 Pfam PF13177 DNA polymerase III, delta subunit 20 178 9.6E-47 T 14-10-2018 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 SMART SM00382 37 185 2.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 Gene3D G3DSA:1.20.272.10 242 362 3.3E-10 T 14-10-2018 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 7.1E-6 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 7.1E-6 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 SUPERFAMILY SSF52540 31 224 7.83E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 Gene3D G3DSA:3.40.50.300 13 177 3.9E-108 T 14-10-2018 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 3.6E-148 T 14-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 360 5.6E-14 T 14-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 C2I25_11520 fb2fea585301b196d3c084cde486bd34 562 Gene3D G3DSA:1.10.8.60 8 238 3.9E-108 T 14-10-2018 C2I25_11855 e34aff5f8f053ec3ed53277f719dff05 215 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 7 214 3.3E-61 T 14-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 C2I25_11855 e34aff5f8f053ec3ed53277f719dff05 215 Pfam PF03006 Haemolysin-III related 4 207 6.6E-47 T 14-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 C2I25_02760 1d3795cb7ea2c72e8aea3f689f2acb6b 140 Pfam PF06713 Bacterial PH domain 54 128 5.7E-20 T 14-10-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 C2I25_08205 bd0b53aec3425ae82ad0c227e697824a 308 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 276 1.1E-7 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I25_08205 bd0b53aec3425ae82ad0c227e697824a 308 SMART SM00382 39 238 1.5E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08205 bd0b53aec3425ae82ad0c227e697824a 308 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_08205 bd0b53aec3425ae82ad0c227e697824a 308 Gene3D G3DSA:3.40.50.300 1 306 2.3E-90 T 14-10-2018 C2I25_08205 bd0b53aec3425ae82ad0c227e697824a 308 Pfam PF00005 ABC transporter 31 181 5.5E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_08205 bd0b53aec3425ae82ad0c227e697824a 308 SUPERFAMILY SSF52540 3 253 5.21E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 4.2E-8 T 14-10-2018 C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.2E-8 T 14-10-2018 C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 SUPERFAMILY SSF51905 1 189 6.78E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 1.3E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 1.3E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.3E-12 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 191 1.2E-40 T 14-10-2018 C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 Gene3D G3DSA:3.50.50.60 1 346 1.1E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_22470 89264e8d53336ffa62bf436b86f06ec7 347 SUPERFAMILY SSF51905 162 317 2.01E-9 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_24100 07cd3909364f1d00adfdb83203dd9954 294 Gene3D G3DSA:1.20.1260.130 13 294 5.4E-105 T 14-10-2018 C2I25_24100 07cd3909364f1d00adfdb83203dd9954 294 SUPERFAMILY SSF47240 11 292 3.35E-90 T 14-10-2018 IPR009078 Ferritin-like superfamily C2I25_24100 07cd3909364f1d00adfdb83203dd9954 294 Pfam PF05067 Manganese containing catalase 11 283 5.8E-69 T 14-10-2018 IPR007760 Manganese catalase C2I25_05290 3788fc662ff1f5306d99682c1b23a180 119 Pfam PF07098 Protein of unknown function (DUF1360) 11 112 1.9E-37 T 14-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 C2I25_08735 b3dc44e17fddd4431e0bf0c6f26357ca 391 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 7 387 31.536 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 C2I25_08735 b3dc44e17fddd4431e0bf0c6f26357ca 391 Pfam PF04285 Protein of unknown function (DUF444) 11 186 6.2E-35 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 C2I25_08735 b3dc44e17fddd4431e0bf0c6f26357ca 391 Pfam PF04285 Protein of unknown function (DUF444) 192 385 2.2E-68 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 C2I25_08735 b3dc44e17fddd4431e0bf0c6f26357ca 391 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 10 382 9.2E-182 T 14-10-2018 IPR014230 Sporulation protein YhbH C2I25_14260 c0f35d79806289c7a22a7374ad2d3c46 244 SMART SM00422 3 72 9.5E-27 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_14260 c0f35d79806289c7a22a7374ad2d3c46 244 Gene3D G3DSA:1.10.490.50 155 243 6.2E-23 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain C2I25_14260 c0f35d79806289c7a22a7374ad2d3c46 244 SUPERFAMILY SSF89082 156 242 9.55E-30 T 14-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain C2I25_14260 c0f35d79806289c7a22a7374ad2d3c46 244 Pfam PF07739 TipAS antibiotic-recognition domain 130 238 7.2E-32 T 14-10-2018 IPR012925 TipAS antibiotic-recognition domain C2I25_14260 c0f35d79806289c7a22a7374ad2d3c46 244 Gene3D G3DSA:1.10.1660.10 1 139 1.6E-52 T 14-10-2018 C2I25_14260 c0f35d79806289c7a22a7374ad2d3c46 244 SUPERFAMILY SSF46955 3 114 1.68E-30 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_14260 c0f35d79806289c7a22a7374ad2d3c46 244 Pfam PF13411 MerR HTH family regulatory protein 3 69 1.1E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_17670 886ed0d5dff4afc898edd240d0db5531 367 Pfam PF03418 Germination protease 17 366 6.8E-195 T 14-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I25_17670 886ed0d5dff4afc898edd240d0db5531 367 Gene3D G3DSA:3.40.50.1450 1 367 3.5E-131 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily C2I25_17670 886ed0d5dff4afc898edd240d0db5531 367 PIRSF PIRSF019549 3 367 7.1E-190 T 14-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I25_17670 886ed0d5dff4afc898edd240d0db5531 367 Hamap MF_00626 Germination protease [gpr]. 1 367 167.368 T 14-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I25_17670 886ed0d5dff4afc898edd240d0db5531 367 TIGRFAM TIGR01441 GPR: GPR endopeptidase 10 367 3.7E-184 T 14-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I25_17670 886ed0d5dff4afc898edd240d0db5531 367 SUPERFAMILY SSF53163 3 367 6.15E-132 T 14-10-2018 IPR023430 Peptidase HybD-like domain superfamily C2I25_17670 886ed0d5dff4afc898edd240d0db5531 367 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 367 0.0 T 14-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I25_14275 7481d4bc67e0617fb0c405d4cb333a23 165 Gene3D G3DSA:3.10.290.10 103 165 2.2E-12 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_14275 7481d4bc67e0617fb0c405d4cb333a23 165 SUPERFAMILY SSF55174 115 163 1.0E-7 T 14-10-2018 C2I25_09725 c8fa3c230d70f03ef55c6da91e8a5083 163 Pfam PF11611 Domain of unknown function (DUF4352) 40 148 7.3E-14 T 14-10-2018 IPR029051 Domain of unknown function DUF4352 C2I25_09725 c8fa3c230d70f03ef55c6da91e8a5083 163 Gene3D G3DSA:2.60.40.1240 39 162 3.9E-18 T 14-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily C2I25_13525 a60def496393220e17bb0c8107adfcb2 342 Pfam PF04198 Putative sugar-binding domain 90 336 2.9E-69 T 14-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 C2I25_13525 a60def496393220e17bb0c8107adfcb2 342 SUPERFAMILY SSF100950 90 336 7.78E-69 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_13525 a60def496393220e17bb0c8107adfcb2 342 Gene3D G3DSA:1.10.10.10 19 91 6.7E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_13525 a60def496393220e17bb0c8107adfcb2 342 Gene3D G3DSA:3.40.50.1360 92 338 6.7E-82 T 14-10-2018 C2I25_13525 a60def496393220e17bb0c8107adfcb2 342 SUPERFAMILY SSF46785 19 81 7.35E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02635 bd621ad6e4b96e9c8acafa8cd181da2f 381 Gene3D G3DSA:3.40.1710.10 44 147 4.6E-6 T 14-10-2018 C2I25_02635 bd621ad6e4b96e9c8acafa8cd181da2f 381 Pfam PF12698 ABC-2 family transporter protein 19 369 2.6E-43 T 14-10-2018 C2I25_17025 b7089feae95ccb7acc5e656b604b310d 181 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 11 163 1.0E-28 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 C2I25_17025 b7089feae95ccb7acc5e656b604b310d 181 Pfam PF04093 rod shape-determining protein MreD 7 166 2.0E-24 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 C2I25_17480 dd6c797f21c97f0744841faab0ac74f4 134 Pfam PF07681 DoxX 7 87 6.5E-21 T 14-10-2018 IPR032808 DoxX family C2I25_25130 768b97d505368fba313d43ef498064be 321 Gene3D G3DSA:3.90.245.10 5 319 7.6E-69 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_25130 768b97d505368fba313d43ef498064be 321 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 6 308 7.0E-60 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain C2I25_25130 768b97d505368fba313d43ef498064be 321 SUPERFAMILY SSF53590 6 315 6.41E-77 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_28435 329479c47f388d57daa08fd616b790b0 71 Gene3D G3DSA:1.10.150.260 2 70 4.1E-24 T 14-10-2018 IPR036806 YozE SAM-like superfamily C2I25_28435 329479c47f388d57daa08fd616b790b0 71 Hamap MF_01538 UPF0346 protein . 1 70 23.177 T 14-10-2018 IPR010673 Protein of unknown function UPF0346 C2I25_28435 329479c47f388d57daa08fd616b790b0 71 SUPERFAMILY SSF140652 2 70 2.62E-25 T 14-10-2018 IPR036806 YozE SAM-like superfamily C2I25_28435 329479c47f388d57daa08fd616b790b0 71 Pfam PF06855 YozE SAM-like fold 4 69 4.3E-24 T 14-10-2018 IPR023089 YozE SAM-like domain C2I25_28435 329479c47f388d57daa08fd616b790b0 71 PIRSF PIRSF037262 1 71 2.7E-30 T 14-10-2018 IPR010673 Protein of unknown function UPF0346 C2I25_24825 58320e92ceb35a4c1b8ab02fe8daf450 390 Pfam PF13530 Sterol carrier protein domain 180 386 5.6E-53 T 14-10-2018 IPR025559 Enhanced intracellular survival protein domain C2I25_24825 58320e92ceb35a4c1b8ab02fe8daf450 390 Gene3D G3DSA:3.40.630.30 136 287 1.1E-64 T 14-10-2018 C2I25_24825 58320e92ceb35a4c1b8ab02fe8daf450 390 Pfam PF13527 Acetyltransferase (GNAT) domain 10 132 4.6E-37 T 14-10-2018 C2I25_24825 58320e92ceb35a4c1b8ab02fe8daf450 390 SUPERFAMILY SSF55729 6 285 1.18E-73 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24825 58320e92ceb35a4c1b8ab02fe8daf450 390 Gene3D G3DSA:3.30.1050.10 288 380 2.0E-27 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily C2I25_24825 58320e92ceb35a4c1b8ab02fe8daf450 390 Gene3D G3DSA:3.40.630.30 3 135 1.8E-57 T 14-10-2018 C2I25_24825 58320e92ceb35a4c1b8ab02fe8daf450 390 SUPERFAMILY SSF55718 286 390 4.71E-26 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily C2I25_13335 0219686f092bd7fa0531a0f495f96026 103 SUPERFAMILY SSF117782 1 103 7.19E-36 T 14-10-2018 IPR035439 UPF0145 domain superfamily C2I25_13335 0219686f092bd7fa0531a0f495f96026 103 Pfam PF01906 Putative heavy-metal-binding 1 103 6.5E-37 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 C2I25_13335 0219686f092bd7fa0531a0f495f96026 103 Gene3D G3DSA:3.30.110.70 1 103 8.8E-43 T 14-10-2018 C2I25_13335 0219686f092bd7fa0531a0f495f96026 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.046 T 14-10-2018 IPR002765 Uncharacterised protein family UPF0145 C2I25_05845 da5aae25bdc67715fe3208321e2d4f8d 110 Gene3D G3DSA:1.10.10.10 10 110 9.1E-42 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_05845 da5aae25bdc67715fe3208321e2d4f8d 110 Pfam PF01638 HxlR-like helix-turn-helix 20 106 3.5E-33 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_05845 da5aae25bdc67715fe3208321e2d4f8d 110 SUPERFAMILY SSF46785 11 105 5.18E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_15170 df76b9b26462aa9d12cf7d820eaa1e71 134 Pfam PF03994 Domain of Unknown Function (DUF350) 12 65 1.0E-5 T 14-10-2018 IPR007140 Protein of unknown function DUF350 C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 5.6E-6 T 14-10-2018 C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 5.6E-6 T 14-10-2018 C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 5.6E-6 T 14-10-2018 C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 355 375 5.6E-6 T 14-10-2018 C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 489 3.8E-89 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 Pfam PF07690 Major Facilitator Superfamily 15 406 4.2E-58 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 SUPERFAMILY SSF103473 10 500 6.54E-78 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 Gene3D G3DSA:1.20.1250.20 263 500 4.9E-21 T 14-10-2018 C2I25_25185 3b7df1d12de579cdc46c157196a314a1 511 Gene3D G3DSA:1.20.1720.10 12 214 5.8E-55 T 14-10-2018 C2I25_18565 a7010e24b1cbd9ea472d5dcd6f7cb2d9 77 Pfam PF11118 Protein of unknown function (DUF2627) 2 77 2.2E-29 T 14-10-2018 IPR020138 Uncharacterised protein family YqzF C2I25_18565 a7010e24b1cbd9ea472d5dcd6f7cb2d9 77 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 2.0E-29 T 14-10-2018 IPR020138 Uncharacterised protein family YqzF C2I25_19830 92e028b0ffc4494abc4780e380dc878b 150 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 11 116 8.1E-23 T 14-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA C2I25_19830 92e028b0ffc4494abc4780e380dc878b 150 SUPERFAMILY SSF158622 6 127 3.27E-34 T 14-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I25_19830 92e028b0ffc4494abc4780e380dc878b 150 Gene3D G3DSA:1.20.1500.10 5 127 6.8E-30 T 14-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I25_07425 fddcbd318d7a4508b7a2c0934fac67fc 254 Pfam PF01925 Sulfite exporter TauE/SafE 7 247 2.6E-41 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I25_17920 6b4631801e7c894cd293e5d67a5f788d 709 SUPERFAMILY SSF56519 58 316 1.96E-34 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_17920 6b4631801e7c894cd293e5d67a5f788d 709 Gene3D G3DSA:3.90.1310.30 64 568 9.7E-230 T 14-10-2018 C2I25_17920 6b4631801e7c894cd293e5d67a5f788d 709 Gene3D G3DSA:1.10.10.1230 89 191 9.7E-230 T 14-10-2018 C2I25_17920 6b4631801e7c894cd293e5d67a5f788d 709 SUPERFAMILY SSF56601 290 688 2.41E-69 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_17920 6b4631801e7c894cd293e5d67a5f788d 709 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 302 4.4E-36 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_17920 6b4631801e7c894cd293e5d67a5f788d 709 Gene3D G3DSA:3.40.710.10 316 674 9.7E-230 T 14-10-2018 C2I25_17920 6b4631801e7c894cd293e5d67a5f788d 709 Pfam PF00905 Penicillin binding protein transpeptidase domain 347 680 4.4E-69 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_14085 e84249ff474e52bb80fbe460b86f1682 82 Pfam PF07875 Coat F domain 2 63 2.2E-18 T 14-10-2018 IPR012851 Spore coat protein CotF-like C2I25_06015 c9fac33a9c17fe55e08eda784501c8f4 133 Gene3D G3DSA:1.10.4040.10 74 125 5.3E-16 T 14-10-2018 C2I25_06015 c9fac33a9c17fe55e08eda784501c8f4 133 PIRSF PIRSF019455 1 133 4.5E-40 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 C2I25_06015 c9fac33a9c17fe55e08eda784501c8f4 133 Pfam PF03965 Penicillinase repressor 8 123 3.1E-39 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 C2I25_06015 c9fac33a9c17fe55e08eda784501c8f4 133 Gene3D G3DSA:1.10.10.10 9 73 6.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_06015 c9fac33a9c17fe55e08eda784501c8f4 133 SUPERFAMILY SSF46785 6 126 4.89E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_00190 b9669e4bbfd19fb8930e4c7b12674c3d 328 Gene3D G3DSA:2.30.30.40 188 254 6.2E-8 T 14-10-2018 C2I25_00190 b9669e4bbfd19fb8930e4c7b12674c3d 328 Gene3D G3DSA:3.40.630.40 1 181 1.0E-50 T 14-10-2018 C2I25_00190 b9669e4bbfd19fb8930e4c7b12674c3d 328 Gene3D G3DSA:2.30.30.40 269 324 2.8E-6 T 14-10-2018 C2I25_00190 b9669e4bbfd19fb8930e4c7b12674c3d 328 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 175 5.9E-44 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_00190 b9669e4bbfd19fb8930e4c7b12674c3d 328 SUPERFAMILY SSF53187 1 180 9.42E-49 T 14-10-2018 C2I25_00190 b9669e4bbfd19fb8930e4c7b12674c3d 328 SMART SM00646 62 175 4.7E-32 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I25_11925 332a28ee71a32167a5df947c1742c7ae 338 SUPERFAMILY SSF51735 1 335 1.23E-99 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_11925 332a28ee71a32167a5df947c1742c7ae 338 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 4.0E-5 T 14-10-2018 C2I25_11925 332a28ee71a32167a5df947c1742c7ae 338 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 4.0E-5 T 14-10-2018 C2I25_11925 332a28ee71a32167a5df947c1742c7ae 338 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 4.0E-5 T 14-10-2018 C2I25_11925 332a28ee71a32167a5df947c1742c7ae 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 1.5E-65 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_11925 332a28ee71a32167a5df947c1742c7ae 338 Gene3D G3DSA:3.40.50.720 3 273 3.6E-149 T 14-10-2018 C2I25_11925 332a28ee71a32167a5df947c1742c7ae 338 Gene3D G3DSA:3.90.25.10 193 328 3.6E-149 T 14-10-2018 C2I25_11925 332a28ee71a32167a5df947c1742c7ae 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 8.2E-150 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 C2I25_09860 6c2ed63385681d2844ce7b840ae1ec8e 125 Pfam PF11127 Protein of unknown function (DUF2892) 1 60 2.8E-11 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 C2I25_16705 910b7ad39542480a68ea1813bc56f841 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 5.1E-65 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I25_16705 910b7ad39542480a68ea1813bc56f841 258 Gene3D G3DSA:3.90.226.10 1 258 1.3E-93 T 14-10-2018 C2I25_16705 910b7ad39542480a68ea1813bc56f841 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I25_16705 910b7ad39542480a68ea1813bc56f841 258 SUPERFAMILY SSF52096 2 258 3.58E-83 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_18430 f3d329a49b5a1efd0d04a821a64eeaa5 296 Gene3D G3DSA:1.10.600.10 2 296 1.9E-106 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I25_18430 f3d329a49b5a1efd0d04a821a64eeaa5 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 98 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site C2I25_18430 f3d329a49b5a1efd0d04a821a64eeaa5 296 SUPERFAMILY SSF48576 8 276 2.34E-87 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I25_18430 f3d329a49b5a1efd0d04a821a64eeaa5 296 Pfam PF00348 Polyprenyl synthetase 32 269 4.6E-60 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 C2I25_18430 f3d329a49b5a1efd0d04a821a64eeaa5 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site C2I25_18360 0faccc829ae27dccef93d93c60c4d23a 67 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 1.8E-29 T 14-10-2018 IPR009570 Stage III sporulation protein AC C2I25_18360 0faccc829ae27dccef93d93c60c4d23a 67 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 2.0E-14 T 14-10-2018 IPR025664 Stage III sporulation protein AC/AD family C2I25_11105 651ccf84d5a230a8b41c04f4c9a12a23 367 SUPERFAMILY SSF88723 167 295 1.71E-25 T 14-10-2018 IPR029060 PIN-like domain superfamily C2I25_11105 651ccf84d5a230a8b41c04f4c9a12a23 367 SMART SM00670 167 274 1.0E-13 T 14-10-2018 IPR002716 PIN domain C2I25_11105 651ccf84d5a230a8b41c04f4c9a12a23 367 Gene3D G3DSA:3.40.50.1010 163 298 6.8E-54 T 14-10-2018 C2I25_26230 40e5736295fca1ae6740f5d98f84ebe6 291 SUPERFAMILY SSF51695 38 285 3.66E-76 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_26230 40e5736295fca1ae6740f5d98f84ebe6 291 Gene3D G3DSA:3.20.20.190 20 290 1.8E-98 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_26230 40e5736295fca1ae6740f5d98f84ebe6 291 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 44 279 2.2E-48 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I25_17650 12f8702dde6f6fb2d2c3420b09a0e08f 773 Pfam PF13567 Domain of unknown function (DUF4131) 21 164 5.3E-21 T 14-10-2018 IPR025405 Domain of unknown function DUF4131 C2I25_17650 12f8702dde6f6fb2d2c3420b09a0e08f 773 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 228 398 6.5E-35 T 14-10-2018 IPR004477 ComEC/Rec2-related protein C2I25_17650 12f8702dde6f6fb2d2c3420b09a0e08f 773 Gene3D G3DSA:3.60.15.10 499 765 7.1E-75 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_17650 12f8702dde6f6fb2d2c3420b09a0e08f 773 Pfam PF00753 Metallo-beta-lactamase superfamily 507 718 5.0E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_17650 12f8702dde6f6fb2d2c3420b09a0e08f 773 SUPERFAMILY SSF56281 502 761 1.11E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_17650 12f8702dde6f6fb2d2c3420b09a0e08f 773 SMART SM00849 509 719 3.7E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_17650 12f8702dde6f6fb2d2c3420b09a0e08f 773 Pfam PF03772 Competence protein 207 469 1.8E-64 T 14-10-2018 IPR004477 ComEC/Rec2-related protein C2I25_17650 12f8702dde6f6fb2d2c3420b09a0e08f 773 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 78 748 4.4E-131 T 14-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 C2I25_26655 71bff34100c6288e54a1599b5cc58748 160 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 7 151 1.5E-22 T 14-10-2018 IPR006524 Transcription activator, ArpU family C2I25_23865 2425d5eaba953da5910811c2c7c80f7a 194 SUPERFAMILY SSF46689 8 75 4.31E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_23865 2425d5eaba953da5910811c2c7c80f7a 194 Gene3D G3DSA:1.10.357.10 5 194 1.5E-37 T 14-10-2018 C2I25_23865 2425d5eaba953da5910811c2c7c80f7a 194 SUPERFAMILY SSF48498 82 194 5.93E-15 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_23865 2425d5eaba953da5910811c2c7c80f7a 194 Pfam PF16925 Bacterial transcriptional repressor C-terminal 83 193 1.3E-8 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal C2I25_23865 2425d5eaba953da5910811c2c7c80f7a 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 3.7E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_23865 2425d5eaba953da5910811c2c7c80f7a 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_23865 2425d5eaba953da5910811c2c7c80f7a 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 6.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_12140 137badac3c76f447ebc274dace5e3a38 432 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 422 5.0E-126 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_12140 137badac3c76f447ebc274dace5e3a38 432 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 422 3.0E-181 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 C2I25_12140 137badac3c76f447ebc274dace5e3a38 432 SUPERFAMILY SSF53383 24 422 6.54E-110 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_12140 137badac3c76f447ebc274dace5e3a38 432 Gene3D G3DSA:3.90.1150.10 291 431 8.9E-51 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_12140 137badac3c76f447ebc274dace5e3a38 432 Gene3D G3DSA:3.40.640.10 7 287 1.0E-88 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_12140 137badac3c76f447ebc274dace5e3a38 432 PIRSF PIRSF001434 3 424 2.1E-122 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I25_24920 c875cba91b3c2ea18ea8ddcd2138655d 133 SUPERFAMILY SSF55729 12 125 2.03E-13 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24920 c875cba91b3c2ea18ea8ddcd2138655d 133 Gene3D G3DSA:3.40.630.30 3 122 3.9E-12 T 14-10-2018 C2I25_24920 c875cba91b3c2ea18ea8ddcd2138655d 133 Pfam PF13673 Acetyltransferase (GNAT) domain 42 116 1.2E-10 T 14-10-2018 IPR000182 GNAT domain C2I25_23380 ce4a773ed195e5d1ad6cb5e5f5bbca70 66 Pfam PF14044 NETI protein 9 64 2.3E-30 T 14-10-2018 IPR025930 NETI protein C2I25_14065 d3ae016ea2286ca34eacfc390ad4bcef 240 Gene3D G3DSA:3.60.15.10 6 239 2.9E-39 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_14065 d3ae016ea2286ca34eacfc390ad4bcef 240 SMART SM00849 20 212 7.1E-34 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_14065 d3ae016ea2286ca34eacfc390ad4bcef 240 SUPERFAMILY SSF56281 6 227 2.62E-43 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_14065 d3ae016ea2286ca34eacfc390ad4bcef 240 Pfam PF00753 Metallo-beta-lactamase superfamily 18 212 1.4E-29 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_17720 9757fec591ae63ab6058e8ea17802663 249 Gene3D G3DSA:2.40.240.20 1 69 3.7E-19 T 14-10-2018 C2I25_17720 9757fec591ae63ab6058e8ea17802663 249 SUPERFAMILY SSF88697 1 67 1.32E-11 T 14-10-2018 IPR015947 PUA-like superfamily C2I25_17720 9757fec591ae63ab6058e8ea17802663 249 Pfam PF04452 RNA methyltransferase 17 243 2.3E-73 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 C2I25_17720 9757fec591ae63ab6058e8ea17802663 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 5 248 3.0E-70 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 C2I25_17720 9757fec591ae63ab6058e8ea17802663 249 SUPERFAMILY SSF75217 72 248 2.09E-56 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I25_17720 9757fec591ae63ab6058e8ea17802663 249 Gene3D G3DSA:3.40.1280.10 71 249 1.2E-65 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I25_17720 9757fec591ae63ab6058e8ea17802663 249 PIRSF PIRSF015601 1 248 5.0E-64 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 C2I25_06315 0b9e979cc06d288574e32b9ee292faeb 370 Gene3D G3DSA:1.25.40.10 1 369 6.9E-95 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_06315 0b9e979cc06d288574e32b9ee292faeb 370 SMART SM00028 97 130 120.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_06315 0b9e979cc06d288574e32b9ee292faeb 370 SMART SM00028 252 285 40.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_06315 0b9e979cc06d288574e32b9ee292faeb 370 SMART SM00028 178 211 31.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_06315 0b9e979cc06d288574e32b9ee292faeb 370 SMART SM00028 218 251 14.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I25_06315 0b9e979cc06d288574e32b9ee292faeb 370 SUPERFAMILY SSF48452 184 303 9.49E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_06315 0b9e979cc06d288574e32b9ee292faeb 370 SUPERFAMILY SSF48452 98 206 1.05E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_06315 0b9e979cc06d288574e32b9ee292faeb 370 Pfam PF13424 Tetratricopeptide repeat 184 246 9.0E-9 T 14-10-2018 C2I25_04980 4658f93d8e229c4394883ab6e1d3c727 266 SUPERFAMILY SSF161098 4 253 1.14E-60 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_04980 4658f93d8e229c4394883ab6e1d3c727 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 249 3.0E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_04980 4658f93d8e229c4394883ab6e1d3c727 266 Gene3D G3DSA:1.10.3720.10 1 255 3.0E-56 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 355 363 - T 14-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 Gene3D G3DSA:2.40.180.10 1 434 1.8E-202 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 Gene3D G3DSA:3.40.50.880 532 676 3.1E-29 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 PIRSF PIRSF038927 2 676 0.0 T 14-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 SUPERFAMILY SSF56634 5 511 5.89E-216 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 PRINTS PR00067 Catalase signature 342 368 8.4E-65 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 PRINTS PR00067 Catalase signature 141 159 8.4E-65 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 PRINTS PR00067 Catalase signature 38 61 8.4E-65 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 PRINTS PR00067 Catalase signature 310 337 8.4E-65 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 PRINTS PR00067 Catalase signature 101 119 8.4E-65 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 PRINTS PR00067 Catalase signature 122 139 8.4E-65 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 Pfam PF06628 Catalase-related immune-responsive 440 503 1.4E-18 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 SUPERFAMILY SSF52317 533 673 3.09E-12 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 Gene3D G3DSA:1.20.1370.20 435 530 1.4E-31 T 14-10-2018 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 Pfam PF00199 Catalase 25 409 4.7E-178 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 SMART SM01060 25 412 4.2E-265 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_15335 39ce2b9063c1ecf051764f2e0cdebd22 676 ProSitePatterns PS00438 Catalase proximal active site signature. 61 77 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I25_17390 9cda886de63418e83f65187a531ada1e 220 Pfam PF07423 Protein of unknown function (DUF1510) 5 219 7.4E-71 T 14-10-2018 IPR009988 Protein of unknown function DUF1510 C2I25_27875 094d65005bc3b78f05909b121313a4a4 375 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 108 332 1.1E-68 T 14-10-2018 IPR005079 Peptidase C45 C2I25_27875 094d65005bc3b78f05909b121313a4a4 375 Gene3D G3DSA:3.60.60.10 79 344 2.9E-39 T 14-10-2018 C2I25_27875 094d65005bc3b78f05909b121313a4a4 375 SUPERFAMILY SSF56235 108 231 1.31E-5 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_15205 8ba0e3153aaf315b7dced73caced1e7a 342 PIRSF PIRSF000267 1 342 9.8E-128 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I25_15205 8ba0e3153aaf315b7dced73caced1e7a 342 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 329 9.1E-91 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I25_15205 8ba0e3153aaf315b7dced73caced1e7a 342 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 215 1.2E-52 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I25_25350 735f74d6898f2e9caf41a6418891a0a9 393 Pfam PF04914 DltD protein 41 391 1.2E-125 T 14-10-2018 IPR006998 DltD C2I25_25350 735f74d6898f2e9caf41a6418891a0a9 393 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 7 390 2.4E-140 T 14-10-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes C2I25_25350 735f74d6898f2e9caf41a6418891a0a9 393 PIRSF PIRSF021438 1 393 1.4E-165 T 14-10-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes C2I25_25350 735f74d6898f2e9caf41a6418891a0a9 393 Gene3D G3DSA:3.40.50.1110 234 393 1.1E-6 T 14-10-2018 IPR036514 SGNH hydrolase superfamily C2I25_25350 735f74d6898f2e9caf41a6418891a0a9 393 SUPERFAMILY SSF52266 230 391 2.56E-17 T 14-10-2018 C2I25_20485 c19de610d24e01eef7185639e32c3a9f 299 Gene3D G3DSA:3.20.20.370 60 297 7.5E-61 T 14-10-2018 C2I25_20485 c19de610d24e01eef7185639e32c3a9f 299 Pfam PF01522 Polysaccharide deacetylase 106 224 9.5E-30 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_20485 c19de610d24e01eef7185639e32c3a9f 299 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 27 294 1.0E-151 T 14-10-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY C2I25_20485 c19de610d24e01eef7185639e32c3a9f 299 SUPERFAMILY SSF88713 78 294 5.12E-62 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_22155 8e97c8a9ba24ce9f22733ce34313af85 132 Pfam PF11070 Protein of unknown function (DUF2871) 1 128 1.1E-36 T 14-10-2018 IPR021299 Protein of unknown function DUF2871 C2I25_18665 ce5a009d1c010247e97b592a2c76074a 186 Gene3D G3DSA:2.40.440.10 13 178 3.3E-44 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I25_18665 ce5a009d1c010247e97b592a2c76074a 186 Pfam PF03734 L,D-transpeptidase catalytic domain 28 151 2.1E-23 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I25_18665 ce5a009d1c010247e97b592a2c76074a 186 SUPERFAMILY SSF141523 26 151 1.83E-33 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I25_15490 c0fb72810a40b2496f36bb440c591803 277 Gene3D G3DSA:3.40.50.300 1 255 8.4E-48 T 14-10-2018 C2I25_15490 c0fb72810a40b2496f36bb440c591803 277 Pfam PF00005 ABC transporter 18 151 7.3E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_15490 c0fb72810a40b2496f36bb440c591803 277 SUPERFAMILY SSF52540 2 204 7.68E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_15490 c0fb72810a40b2496f36bb440c591803 277 SMART SM00382 27 211 4.8E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_04925 1b0d60e0254b24c24e545873dddbecb9 324 Gene3D G3DSA:2.130.10.10 16 199 9.0E-20 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_04925 1b0d60e0254b24c24e545873dddbecb9 324 Gene3D G3DSA:2.130.10.10 225 316 2.3E-13 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_04925 1b0d60e0254b24c24e545873dddbecb9 324 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 283 315 1.1E-7 T 14-10-2018 IPR011964 YVTN beta-propeller repeat C2I25_04925 1b0d60e0254b24c24e545873dddbecb9 324 SUPERFAMILY SSF51004 27 313 1.96E-45 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily C2I25_09330 5f40792b801b26160cb37e330cc86ce2 437 Gene3D G3DSA:3.40.720.10 2 436 7.8E-78 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_09330 5f40792b801b26160cb37e330cc86ce2 437 SUPERFAMILY SSF53649 7 420 1.01E-78 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_09330 5f40792b801b26160cb37e330cc86ce2 437 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 9 380 6.1E-59 T 14-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 C2I25_14235 0352b7454d6a6109819d9a383808a7b9 298 SUPERFAMILY SSF102114 20 287 4.58E-66 T 14-10-2018 C2I25_14235 0352b7454d6a6109819d9a383808a7b9 298 Gene3D G3DSA:3.20.20.70 18 268 4.3E-26 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_14235 0352b7454d6a6109819d9a383808a7b9 298 Pfam PF04055 Radical SAM superfamily 64 223 3.3E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I25_14235 0352b7454d6a6109819d9a383808a7b9 298 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 146.567 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 C2I25_14235 0352b7454d6a6109819d9a383808a7b9 298 PIRSF PIRSF005963 1 298 8.5E-136 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 C2I25_14235 0352b7454d6a6109819d9a383808a7b9 298 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 5 45 1.9E-10 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 C2I25_14235 0352b7454d6a6109819d9a383808a7b9 298 SMART SM00729 57 265 9.2E-16 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I25_14235 0352b7454d6a6109819d9a383808a7b9 298 TIGRFAM TIGR00510 lipA: lipoyl synthase 2 292 2.4E-121 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 C2I25_23720 82e5fcae5847ad49334c1c9f2ca50ddd 109 Gene3D G3DSA:3.10.450.40 35 109 3.2E-5 T 14-10-2018 C2I25_08930 be9814c27d1a13e709ccb6d268a7ba30 261 Pfam PF06182 ABC-2 family transporter protein 34 260 4.8E-54 T 14-10-2018 IPR010390 Protein of unknown function DUF990 C2I25_01840 8b5548c271fac5767870fad62776a431 254 SUPERFAMILY SSF53474 7 250 1.0E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_01840 8b5548c271fac5767870fad62776a431 254 Pfam PF00561 alpha/beta hydrolase fold 11 238 1.4E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_01840 8b5548c271fac5767870fad62776a431 254 Gene3D G3DSA:3.40.50.1820 1 251 7.0E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_05250 599035f3e273444f0ad4ce98842871c4 303 SUPERFAMILY SSF103481 185 286 8.11E-13 T 14-10-2018 C2I25_05250 599035f3e273444f0ad4ce98842871c4 303 SUPERFAMILY SSF103481 38 140 9.16E-15 T 14-10-2018 C2I25_05250 599035f3e273444f0ad4ce98842871c4 303 Pfam PF00892 EamA-like transporter family 13 136 3.1E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_05250 599035f3e273444f0ad4ce98842871c4 303 Pfam PF00892 EamA-like transporter family 149 282 3.4E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_23590 37fb16748bb9f0c976fe0d9745e95f69 410 Pfam PF13285 Domain of unknown function (DUF4073) 251 407 3.4E-96 T 14-10-2018 IPR025142 Domain of unknown function DUF4073 C2I25_23590 37fb16748bb9f0c976fe0d9745e95f69 410 Pfam PF00149 Calcineurin-like phosphoesterase 35 250 5.1E-13 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_23590 37fb16748bb9f0c976fe0d9745e95f69 410 SUPERFAMILY SSF56300 34 321 5.22E-33 T 14-10-2018 C2I25_06585 75bef92f15ddae3574cbd8fef4e1b462 197 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 65 87 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I25_06585 75bef92f15ddae3574cbd8fef4e1b462 197 Gene3D G3DSA:1.20.120.1760 3 187 9.5E-18 T 14-10-2018 C2I25_06585 75bef92f15ddae3574cbd8fef4e1b462 197 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 29 181 1.1E-54 T 14-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 C2I25_06585 75bef92f15ddae3574cbd8fef4e1b462 197 Pfam PF01066 CDP-alcohol phosphatidyltransferase 24 87 8.5E-16 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I25_06860 5d1f84806b4fcbd6cf29873be1c1353e 283 SUPERFAMILY SSF161098 75 261 9.68E-25 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_06860 5d1f84806b4fcbd6cf29873be1c1353e 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 276 3.0E-30 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_06860 5d1f84806b4fcbd6cf29873be1c1353e 283 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 7 55 4.0E-6 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I25_06860 5d1f84806b4fcbd6cf29873be1c1353e 283 Gene3D G3DSA:1.10.3720.10 66 275 4.3E-20 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_21190 693d7fbfae82b5f4b3468799d56b08f9 143 ProDom PD086666 YNEK BH2332 11 143 2.0E-63 T 14-10-2018 IPR020203 Uncharacterised protein family, YneK C2I25_21190 693d7fbfae82b5f4b3468799d56b08f9 143 Pfam PF11084 Protein of unknown function (DUF2621) 3 141 7.4E-76 T 14-10-2018 IPR020203 Uncharacterised protein family, YneK C2I25_22865 20bd3720189596d902d3e435b84c97b1 742 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 140 403 3.4E-20 T 14-10-2018 IPR031161 Peptidase family M60 domain C2I25_22865 20bd3720189596d902d3e435b84c97b1 742 Pfam PF03272 Putative mucin or carbohydrate-binding module 561 672 6.2E-32 T 14-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain C2I25_22865 20bd3720189596d902d3e435b84c97b1 742 Gene3D G3DSA:1.10.390.30 277 439 4.2E-8 T 14-10-2018 C2I25_22865 20bd3720189596d902d3e435b84c97b1 742 SMART SM01276 53 352 5.6E-45 T 14-10-2018 IPR031161 Peptidase family M60 domain C2I25_12450 be828d1e4b557457576f9435cb0abbfc 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 183 1.7E-68 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I25_12450 be828d1e4b557457576f9435cb0abbfc 283 PIRSF PIRSF000105 1 283 1.2E-95 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 C2I25_12450 be828d1e4b557457576f9435cb0abbfc 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 14-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I25_12450 be828d1e4b557457576f9435cb0abbfc 283 SUPERFAMILY SSF48179 185 283 1.11E-33 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_12450 be828d1e4b557457576f9435cb0abbfc 283 Gene3D G3DSA:1.10.1040.10 193 278 8.3E-36 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_12450 be828d1e4b557457576f9435cb0abbfc 283 Gene3D G3DSA:3.40.50.720 1 188 1.3E-74 T 14-10-2018 C2I25_12450 be828d1e4b557457576f9435cb0abbfc 283 SUPERFAMILY SSF51735 3 185 1.53E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_12450 be828d1e4b557457576f9435cb0abbfc 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 7.0E-36 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I25_28410 80ff4759f98bbc3f0f92afedaa3c28d7 273 SMART SM00219 24 254 6.5E-4 T 14-10-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 C2I25_28410 80ff4759f98bbc3f0f92afedaa3c28d7 273 Gene3D G3DSA:1.10.510.10 15 267 2.0E-39 T 14-10-2018 C2I25_28410 80ff4759f98bbc3f0f92afedaa3c28d7 273 SUPERFAMILY SSF56112 12 217 4.99E-45 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_28410 80ff4759f98bbc3f0f92afedaa3c28d7 273 Pfam PF00069 Protein kinase domain 24 202 3.6E-29 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I25_16225 fe0b44d1c686d7557c559a3880545ec0 121 Gene3D G3DSA:2.40.50.140 35 119 3.4E-9 T 14-10-2018 C2I25_16225 fe0b44d1c686d7557c559a3880545ec0 121 Pfam PF11518 Protein of unknown function (DUF3221) 14 119 6.0E-41 T 14-10-2018 IPR021598 Protein of unknown function DUF3221 C2I25_10805 ca887ba7c53142f3967062ae7d0af2e1 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.213 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 C2I25_10805 ca887ba7c53142f3967062ae7d0af2e1 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 9.7E-65 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10805 ca887ba7c53142f3967062ae7d0af2e1 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 14-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 C2I25_10805 ca887ba7c53142f3967062ae7d0af2e1 145 PIRSF PIRSF002181 1 143 2.8E-50 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 C2I25_10805 ca887ba7c53142f3967062ae7d0af2e1 145 Gene3D G3DSA:3.90.1180.10 1 143 6.5E-61 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_10805 ca887ba7c53142f3967062ae7d0af2e1 145 Pfam PF00572 Ribosomal protein L13 15 139 1.0E-56 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 C2I25_10805 ca887ba7c53142f3967062ae7d0af2e1 145 SUPERFAMILY SSF52161 5 143 1.11E-59 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 C2I25_04920 6d00af2d9a57016559c4fb666097c3ba 223 SMART SM00862 148 221 2.5E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_04920 6d00af2d9a57016559c4fb666097c3ba 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 2.2E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I25_04920 6d00af2d9a57016559c4fb666097c3ba 223 SUPERFAMILY SSF52172 1 180 1.85E-46 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_04920 6d00af2d9a57016559c4fb666097c3ba 223 Gene3D G3DSA:3.40.50.2300 1 128 3.0E-44 T 14-10-2018 C2I25_04920 6d00af2d9a57016559c4fb666097c3ba 223 Gene3D G3DSA:1.10.10.10 129 223 1.1E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04920 6d00af2d9a57016559c4fb666097c3ba 223 Pfam PF00072 Response regulator receiver domain 6 114 5.6E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_04920 6d00af2d9a57016559c4fb666097c3ba 223 SMART SM00448 4 114 1.2E-44 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_02745 85660d261d94781604ca52cfcf4c49d2 469 Pfam PF01554 MatE 34 194 4.0E-37 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_02745 85660d261d94781604ca52cfcf4c49d2 469 Pfam PF01554 MatE 263 423 1.4E-31 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_02745 85660d261d94781604ca52cfcf4c49d2 469 TIGRFAM TIGR00797 matE: MATE efflux family protein 34 437 5.6E-96 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_02745 85660d261d94781604ca52cfcf4c49d2 469 PIRSF PIRSF006603 7 468 7.2E-133 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I25_14345 c3051fd3ad42934320b5545e6a901238 333 Gene3D G3DSA:3.90.1200.10 90 313 1.0E-22 T 14-10-2018 C2I25_14345 c3051fd3ad42934320b5545e6a901238 333 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 3 313 5.2E-113 T 14-10-2018 IPR014254 Spore coat protein YutH C2I25_14345 c3051fd3ad42934320b5545e6a901238 333 SUPERFAMILY SSF56112 4 314 2.35E-15 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 2.2E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 2.2E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 2.2E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 2.2E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00412 Epoxide hydrolase signature 254 276 1.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00412 Epoxide hydrolase signature 221 237 1.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00412 Epoxide hydrolase signature 39 57 1.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00412 Epoxide hydrolase signature 103 116 1.1E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 Pfam PF00561 alpha/beta hydrolase fold 33 265 1.6E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 SUPERFAMILY SSF53474 6 276 2.9E-59 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_14620 88e5bbbe2dbbd8403b73dcdac53d7464 279 Gene3D G3DSA:3.40.50.1820 3 279 3.1E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_09610 1c1adca30d13ad834ee41af01bcaa9db 338 SUPERFAMILY SSF81345 9 332 5.89E-79 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_09610 1c1adca30d13ad834ee41af01bcaa9db 338 Pfam PF01032 FecCD transport family 25 332 2.3E-84 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_09610 1c1adca30d13ad834ee41af01bcaa9db 338 Gene3D G3DSA:1.10.3470.10 11 336 2.1E-85 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_21455 85df704dca931cc69c07536164354d69 412 Gene3D G3DSA:1.20.1250.20 13 391 3.4E-48 T 14-10-2018 C2I25_21455 85df704dca931cc69c07536164354d69 412 SUPERFAMILY SSF103473 14 391 1.19E-54 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_21455 85df704dca931cc69c07536164354d69 412 Pfam PF07690 Major Facilitator Superfamily 15 349 6.8E-36 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_21455 85df704dca931cc69c07536164354d69 412 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_12065 a63f416e06ecb1be4fc3ad935dbdff15 490 Pfam PF13425 O-antigen ligase like membrane protein 9 489 1.3E-120 T 14-10-2018 C2I25_22675 406eea88ad4f05cea19faa86c8093c0d 249 Gene3D G3DSA:3.40.1390.30 93 219 6.4E-38 T 14-10-2018 C2I25_22675 406eea88ad4f05cea19faa86c8093c0d 249 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 234 3.5E-43 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 C2I25_22675 406eea88ad4f05cea19faa86c8093c0d 249 SUPERFAMILY SSF102705 1 241 9.03E-49 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily C2I25_22675 406eea88ad4f05cea19faa86c8093c0d 249 Gene3D G3DSA:3.40.1390.30 27 233 6.4E-38 T 14-10-2018 C2I25_09225 61a05787cbbb0523d125a9fcb7126e6e 920 Gene3D G3DSA:3.40.50.300 382 598 4.4E-10 T 14-10-2018 C2I25_09225 61a05787cbbb0523d125a9fcb7126e6e 920 SUPERFAMILY SSF52540 377 578 1.43E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09225 61a05787cbbb0523d125a9fcb7126e6e 920 SUPERFAMILY SSF48452 40 168 3.67E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_09225 61a05787cbbb0523d125a9fcb7126e6e 920 Gene3D G3DSA:1.25.40.10 24 186 5.0E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_10305 7861d05a650b36d646a24ce200e50fae 423 Gene3D G3DSA:1.20.1250.20 11 203 1.1E-34 T 14-10-2018 C2I25_10305 7861d05a650b36d646a24ce200e50fae 423 Gene3D G3DSA:1.20.1250.20 210 423 2.6E-26 T 14-10-2018 C2I25_10305 7861d05a650b36d646a24ce200e50fae 423 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 84 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_10305 7861d05a650b36d646a24ce200e50fae 423 SUPERFAMILY SSF103473 9 415 1.31E-62 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_10305 7861d05a650b36d646a24ce200e50fae 423 Pfam PF07690 Major Facilitator Superfamily 19 363 1.5E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_13795 0f2e8fe182a8aba74df3f8e8a1b39e0a 168 Pfam PF00210 Ferritin-like domain 8 144 1.5E-41 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 C2I25_13795 0f2e8fe182a8aba74df3f8e8a1b39e0a 168 SUPERFAMILY SSF47240 1 160 1.32E-58 T 14-10-2018 IPR009078 Ferritin-like superfamily C2I25_13795 0f2e8fe182a8aba74df3f8e8a1b39e0a 168 Gene3D G3DSA:1.20.1260.10 1 168 1.9E-51 T 14-10-2018 IPR012347 Ferritin-like C2I25_22085 7ad782a5a80ed3ef92a84d00800fda21 471 SMART SM00148 60 206 3.7E-8 T 14-10-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain C2I25_22085 7ad782a5a80ed3ef92a84d00800fda21 471 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 68 204 1.9E-9 T 14-10-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain C2I25_22085 7ad782a5a80ed3ef92a84d00800fda21 471 SUPERFAMILY SSF51695 46 358 1.26E-53 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_22360 92b179107d037994d4be226a9ebdae4c 338 Gene3D G3DSA:1.10.3470.10 9 338 3.8E-93 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_22360 92b179107d037994d4be226a9ebdae4c 338 Pfam PF01032 FecCD transport family 24 336 2.5E-89 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_22360 92b179107d037994d4be226a9ebdae4c 338 SUPERFAMILY SSF81345 9 336 4.71E-80 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_24470 590f043a1af220a2401b317c6a79ccb9 485 Pfam PF07690 Major Facilitator Superfamily 57 380 8.8E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_24470 590f043a1af220a2401b317c6a79ccb9 485 Gene3D G3DSA:1.20.1250.20 22 455 5.9E-70 T 14-10-2018 C2I25_24470 590f043a1af220a2401b317c6a79ccb9 485 SUPERFAMILY SSF103473 20 443 2.22E-74 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_24470 590f043a1af220a2401b317c6a79ccb9 485 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_20490 5b59c6b39b1801c421a51ceb3bc2cfbb 413 Pfam PF05193 Peptidase M16 inactive domain 166 338 1.3E-41 T 14-10-2018 IPR007863 Peptidase M16, C-terminal C2I25_20490 5b59c6b39b1801c421a51ceb3bc2cfbb 413 Gene3D G3DSA:3.30.830.10 1 215 9.7E-83 T 14-10-2018 C2I25_20490 5b59c6b39b1801c421a51ceb3bc2cfbb 413 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 C2I25_20490 5b59c6b39b1801c421a51ceb3bc2cfbb 413 SUPERFAMILY SSF63411 3 204 3.51E-64 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I25_20490 5b59c6b39b1801c421a51ceb3bc2cfbb 413 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 5.9E-51 T 14-10-2018 IPR011765 Peptidase M16, N-terminal C2I25_20490 5b59c6b39b1801c421a51ceb3bc2cfbb 413 Gene3D G3DSA:3.30.830.10 218 412 2.0E-55 T 14-10-2018 C2I25_20490 5b59c6b39b1801c421a51ceb3bc2cfbb 413 SUPERFAMILY SSF63411 228 400 3.36E-45 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I25_02040 fda59a2c79ff1f04e7d67016bde61450 206 Pfam PF07987 Domain of unkown function (DUF1775) 28 148 3.7E-20 T 14-10-2018 IPR012533 YcnI-like C2I25_02040 fda59a2c79ff1f04e7d67016bde61450 206 Gene3D G3DSA:2.60.40.2230 25 168 1.3E-32 T 14-10-2018 IPR038507 YcnI-like superfamily C2I25_22810 10e9fb14eacee77353b001c48a01200c 158 PIRSF PIRSF008757 1 158 8.7E-62 T 14-10-2018 IPR010371 Uncharacterised protein family UPF0303 C2I25_22810 10e9fb14eacee77353b001c48a01200c 158 Pfam PF03928 Haem-degrading 25 152 9.3E-30 T 14-10-2018 IPR005624 Haem-degrading C2I25_22810 10e9fb14eacee77353b001c48a01200c 158 SUPERFAMILY SSF143744 17 155 3.4E-26 T 14-10-2018 IPR038084 GlcG-like domain superfamily C2I25_22810 10e9fb14eacee77353b001c48a01200c 158 Hamap MF_00761 UPF0303 protein . 3 158 34.224 T 14-10-2018 IPR010371 Uncharacterised protein family UPF0303 C2I25_22810 10e9fb14eacee77353b001c48a01200c 158 Gene3D G3DSA:3.30.450.150 2 158 7.9E-51 T 14-10-2018 IPR038084 GlcG-like domain superfamily C2I25_16260 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 Gene3D G3DSA:3.90.1640.10 1 197 9.2E-63 T 14-10-2018 C2I25_16260 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 Pfam PF01368 DHH family 15 153 9.3E-14 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I25_16260 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 Pfam PF02272 DHHA1 domain 179 308 9.6E-14 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I25_16260 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 Gene3D G3DSA:3.10.310.30 199 310 4.4E-35 T 14-10-2018 C2I25_16260 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 SUPERFAMILY SSF64182 13 300 3.14E-74 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily C2I25_14170 e884be915d2f8368c9a80d2f45efdfa3 223 Gene3D G3DSA:1.10.3720.10 10 223 1.8E-45 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_14170 e884be915d2f8368c9a80d2f45efdfa3 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 221 1.6E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_14170 e884be915d2f8368c9a80d2f45efdfa3 223 SUPERFAMILY SSF161098 12 212 2.22E-44 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_16270 49b79b2be6c1856252ca5b892222fb25 114 Pfam PF14034 Sporulation protein YtrH 14 111 2.8E-37 T 14-10-2018 IPR025689 Sporulation protein YtrH C2I25_13070 a3e2cd9be754e04221fd44613f66de22 105 Pfam PF09685 Domain of unknown function (DUF4870) 6 98 2.4E-8 T 14-10-2018 IPR019109 Protein of unknown function DUF4870 C2I25_13070 a3e2cd9be754e04221fd44613f66de22 105 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 104 2.0E-52 T 14-10-2018 C2I25_20740 0177868b8889a244f5c413a69b40c6a2 118 Hamap MF_01143 Holin-like protein CidA [cidA]. 1 118 22.577 T 14-10-2018 IPR023760 Holin-like protein CidA GO:0016021 C2I25_20740 0177868b8889a244f5c413a69b40c6a2 118 Pfam PF03788 LrgA family 18 109 6.6E-23 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 PIRSF PIRSF000485 8 471 1.9E-185 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Gene3D G3DSA:3.40.50.2020 270 434 2.0E-167 T 14-10-2018 C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 456 1.3E-168 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 455 47.602 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Gene3D G3DSA:3.60.20.10 12 457 2.0E-167 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Pfam PF13537 Glutamine amidotransferase domain 93 208 8.0E-22 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 SUPERFAMILY SSF53271 246 463 4.06E-77 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 SUPERFAMILY SSF56235 12 238 2.14E-71 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_09905 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Pfam PF00156 Phosphoribosyl transferase domain 268 381 5.5E-8 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_23985 72c1c8bed26a9efa4e143fbb9a1ccd16 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 361 2.8E-64 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_23985 72c1c8bed26a9efa4e143fbb9a1ccd16 367 Pfam PF03845 Spore germination protein 9 318 1.2E-59 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_23985 72c1c8bed26a9efa4e143fbb9a1ccd16 367 Gene3D G3DSA:1.20.1740.10 5 300 9.3E-11 T 14-10-2018 C2I25_07455 63b29eca4096db2802746a6288a70396 191 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 14 38 - T 14-10-2018 IPR001455 TusA-like domain C2I25_07455 63b29eca4096db2802746a6288a70396 191 Gene3D G3DSA:3.30.110.40 6 79 3.9E-28 T 14-10-2018 IPR036868 TusA-like domain superfamily C2I25_07455 63b29eca4096db2802746a6288a70396 191 Pfam PF00581 Rhodanese-like domain 99 187 6.0E-13 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_07455 63b29eca4096db2802746a6288a70396 191 Gene3D G3DSA:3.40.250.10 80 191 3.4E-25 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_07455 63b29eca4096db2802746a6288a70396 191 SUPERFAMILY SSF64307 4 81 1.19E-25 T 14-10-2018 IPR036868 TusA-like domain superfamily C2I25_07455 63b29eca4096db2802746a6288a70396 191 Pfam PF01206 Sulfurtransferase TusA 13 81 3.2E-22 T 14-10-2018 IPR001455 TusA-like domain C2I25_07455 63b29eca4096db2802746a6288a70396 191 SMART SM00450 98 191 2.8E-19 T 14-10-2018 IPR001763 Rhodanese-like domain C2I25_07455 63b29eca4096db2802746a6288a70396 191 SUPERFAMILY SSF52821 87 187 4.45E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily C2I25_01290 876bd7a60e4b87a0cbf1d4865c32d38b 142 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 140 7.9E-21 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain C2I25_01290 876bd7a60e4b87a0cbf1d4865c32d38b 142 SUPERFAMILY SSF141322 79 139 1.44E-15 T 14-10-2018 C2I25_01290 876bd7a60e4b87a0cbf1d4865c32d38b 142 Gene3D G3DSA:2.40.50.140 78 142 7.5E-19 T 14-10-2018 C2I25_06845 f90ee0b9f49c3608f773121f857b42c2 206 Gene3D G3DSA:3.40.30.10 10 199 7.3E-45 T 14-10-2018 C2I25_06845 f90ee0b9f49c3608f773121f857b42c2 206 Pfam PF01323 DSBA-like thioredoxin domain 11 182 6.1E-10 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 C2I25_06845 f90ee0b9f49c3608f773121f857b42c2 206 Gene3D G3DSA:1.10.472.60 45 171 7.3E-45 T 14-10-2018 C2I25_06845 f90ee0b9f49c3608f773121f857b42c2 206 SUPERFAMILY SSF52833 8 205 3.26E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_20880 4bf7ef072cf129889dd7f1ba46991678 159 SUPERFAMILY SSF55729 4 155 3.31E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_20880 4bf7ef072cf129889dd7f1ba46991678 159 Gene3D G3DSA:3.40.630.30 1 157 5.2E-37 T 14-10-2018 C2I25_20880 4bf7ef072cf129889dd7f1ba46991678 159 Pfam PF13673 Acetyltransferase (GNAT) domain 31 153 1.3E-18 T 14-10-2018 IPR000182 GNAT domain C2I25_06610 0fd255581643bd75ec7bb81b22d53e2b 194 Pfam PF11706 CGNR zinc finger 150 190 1.2E-15 T 14-10-2018 IPR021005 Zinc finger, CGNR C2I25_06610 0fd255581643bd75ec7bb81b22d53e2b 194 SUPERFAMILY SSF160904 5 189 2.22E-33 T 14-10-2018 C2I25_06610 0fd255581643bd75ec7bb81b22d53e2b 194 Gene3D G3DSA:1.10.3300.10 5 191 4.0E-17 T 14-10-2018 IPR023286 ABATE domain superfamily C2I25_06610 0fd255581643bd75ec7bb81b22d53e2b 194 Pfam PF07336 Putative stress-induced transcription regulator 12 143 8.5E-12 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator C2I25_08690 4ec493059e3f17bd5cec43f72f37f121 230 Pfam PF00072 Response regulator receiver domain 7 117 2.2E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_08690 4ec493059e3f17bd5cec43f72f37f121 230 SUPERFAMILY SSF52172 5 158 5.55E-34 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_08690 4ec493059e3f17bd5cec43f72f37f121 230 Gene3D G3DSA:3.40.50.2300 2 143 4.7E-29 T 14-10-2018 C2I25_08690 4ec493059e3f17bd5cec43f72f37f121 230 PIRSF PIRSF006171 3 230 3.8E-83 T 14-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 C2I25_08690 4ec493059e3f17bd5cec43f72f37f121 230 SMART SM00448 5 118 1.5E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_06450 d2643e1d7b2ff4f4c0f08b75ea8efd0e 83 Pfam PF04226 Transglycosylase associated protein 33 78 4.9E-11 T 14-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 Pfam PF03793 PASTA domain 651 703 6.0E-7 T 14-10-2018 IPR005543 PASTA domain C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 Pfam PF03793 PASTA domain 595 646 6.7E-8 T 14-10-2018 IPR005543 PASTA domain C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 SUPERFAMILY SSF56519 59 233 9.16E-39 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 SMART SM00740 651 705 7.8 T 14-10-2018 IPR005543 PASTA domain C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 SMART SM00740 590 649 1.9E-4 T 14-10-2018 IPR005543 PASTA domain C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 Gene3D G3DSA:3.30.70.2110 81 156 6.0E-44 T 14-10-2018 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 Gene3D G3DSA:3.90.1310.10 62 200 6.0E-44 T 14-10-2018 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 Gene3D G3DSA:2.20.70.70 59 219 6.0E-44 T 14-10-2018 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 SUPERFAMILY SSF54184 650 703 7.98E-11 T 14-10-2018 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 Pfam PF00905 Penicillin binding protein transpeptidase domain 262 559 4.6E-82 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 SUPERFAMILY SSF56601 184 586 2.73E-92 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 SUPERFAMILY SSF54184 590 648 5.63E-12 T 14-10-2018 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 Gene3D G3DSA:3.40.710.10 227 578 1.0E-102 T 14-10-2018 C2I25_19915 32f4c37e25b1a3f5a84cfb95ab287d76 716 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 213 8.0E-23 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_12275 8f44eb0e4f4e52c088cb11c2dc6556bc 434 Pfam PF01966 HD domain 61 180 5.2E-17 T 14-10-2018 IPR006674 HD domain C2I25_12275 8f44eb0e4f4e52c088cb11c2dc6556bc 434 Gene3D G3DSA:1.10.3210.10 12 401 7.0E-166 T 14-10-2018 C2I25_12275 8f44eb0e4f4e52c088cb11c2dc6556bc 434 SUPERFAMILY SSF109604 3 413 6.49E-120 T 14-10-2018 C2I25_12275 8f44eb0e4f4e52c088cb11c2dc6556bc 434 SMART SM00471 57 187 3.4E-12 T 14-10-2018 IPR003607 HD/PDEase domain C2I25_12275 8f44eb0e4f4e52c088cb11c2dc6556bc 434 Gene3D G3DSA:1.20.1250.30 235 412 7.0E-166 T 14-10-2018 C2I25_25705 6a061a813c49b599192cbce47325e06f 344 Pfam PF02779 Transketolase, pyrimidine binding domain 4 192 1.1E-55 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_25705 6a061a813c49b599192cbce47325e06f 344 Pfam PF02780 Transketolase, C-terminal domain 206 328 3.6E-43 T 14-10-2018 IPR033248 Transketolase, C-terminal domain C2I25_25705 6a061a813c49b599192cbce47325e06f 344 SUPERFAMILY SSF52922 201 336 6.54E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_25705 6a061a813c49b599192cbce47325e06f 344 Gene3D G3DSA:3.40.50.970 3 204 3.5E-82 T 14-10-2018 C2I25_25705 6a061a813c49b599192cbce47325e06f 344 SUPERFAMILY SSF52518 2 216 7.36E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_25705 6a061a813c49b599192cbce47325e06f 344 Gene3D G3DSA:3.40.50.920 205 337 2.9E-48 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_25705 6a061a813c49b599192cbce47325e06f 344 SMART SM00861 5 192 4.6E-62 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_17930 aeb6734e1a1886039359001c415d384c 316 Gene3D G3DSA:1.10.3720.10 88 315 2.9E-34 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_17930 aeb6734e1a1886039359001c415d384c 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 313 3.8E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_17930 aeb6734e1a1886039359001c415d384c 316 SUPERFAMILY SSF161098 36 308 3.66E-34 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_17930 aeb6734e1a1886039359001c415d384c 316 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 33 312 1.8E-79 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 C2I25_20030 88d80abfb7b663c09d9ed745313da72e 152 TIGRFAM TIGR00077 lspA: signal peptidase II 2 151 5.7E-47 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I25_20030 88d80abfb7b663c09d9ed745313da72e 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 1.3E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I25_20030 88d80abfb7b663c09d9ed745313da72e 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 1.3E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I25_20030 88d80abfb7b663c09d9ed745313da72e 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 1.3E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I25_20030 88d80abfb7b663c09d9ed745313da72e 152 Pfam PF01252 Signal peptidase (SPase) II 6 144 8.3E-40 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I25_20030 88d80abfb7b663c09d9ed745313da72e 152 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 150 16.888 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I25_20030 88d80abfb7b663c09d9ed745313da72e 152 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I25_25315 3f456143e0c010dc6307a1b9a4814c7a 198 Gene3D G3DSA:3.40.50.880 1 197 8.7E-65 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_25315 3f456143e0c010dc6307a1b9a4814c7a 198 SUPERFAMILY SSF52317 6 193 5.62E-51 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_25315 3f456143e0c010dc6307a1b9a4814c7a 198 Pfam PF01965 DJ-1/PfpI family 7 175 1.3E-29 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I25_03605 c8047c08a7761eb23416527814915d6b 140 Pfam PF11122 Inner spore coat protein D 22 115 3.5E-23 T 14-10-2018 IPR020108 Spore coat protein CotD C2I25_03605 c8047c08a7761eb23416527814915d6b 140 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 22 72 1.0E-20 T 14-10-2018 IPR020108 Spore coat protein CotD C2I25_04680 b586eee032279ab43013b80f5b798e4f 200 Gene3D G3DSA:3.40.50.1240 1 195 6.6E-8 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_04680 b586eee032279ab43013b80f5b798e4f 200 SUPERFAMILY SSF53254 51 192 7.92E-15 T 14-10-2018 IPR029033 Histidine phosphatase superfamily C2I25_17470 4aa399d6441eeb36f0eb81aef966c982 125 Pfam PF01575 MaoC like domain 9 101 3.8E-6 T 14-10-2018 IPR002539 MaoC-like dehydratase domain C2I25_17470 4aa399d6441eeb36f0eb81aef966c982 125 SUPERFAMILY SSF54637 5 123 2.59E-21 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_17470 4aa399d6441eeb36f0eb81aef966c982 125 Gene3D G3DSA:3.10.129.10 1 124 2.8E-19 T 14-10-2018 C2I25_16640 5723e4ec82574e41d4004cdab5e4613c 307 SUPERFAMILY SSF52540 3 222 2.92E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16640 5723e4ec82574e41d4004cdab5e4613c 307 Pfam PF00005 ABC transporter 21 161 2.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_16640 5723e4ec82574e41d4004cdab5e4613c 307 SMART SM00382 29 210 1.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_16640 5723e4ec82574e41d4004cdab5e4613c 307 Gene3D G3DSA:3.40.50.300 1 239 1.9E-57 T 14-10-2018 C2I25_16640 5723e4ec82574e41d4004cdab5e4613c 307 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_13155 b39ed186d0140e0c5965236321043ed4 100 SUPERFAMILY SSF52794 1 98 9.68E-36 T 14-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I25_13155 b39ed186d0140e0c5965236321043ed4 100 Gene3D G3DSA:3.40.50.2300 1 100 4.3E-39 T 14-10-2018 C2I25_13155 b39ed186d0140e0c5965236321043ed4 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 3.7E-23 T 14-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I25_13155 b39ed186d0140e0c5965236321043ed4 100 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 93 2.4E-34 T 14-10-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 148 1.5E-50 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 307 5.3E-56 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 Gene3D G3DSA:3.40.50.1370 13 305 2.1E-131 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 Gene3D G3DSA:3.40.50.1370 138 296 2.1E-131 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 8.1E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 271 8.1E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 274 297 8.1E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 8.1E-26 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 310 81.081 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 309 4.2E-130 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 SUPERFAMILY SSF53671 9 310 1.14E-107 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 9.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 9.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 9.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 288 299 9.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 9.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I25_18780 927064a0ea4dd90f7908e4a77abb804e 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 SUPERFAMILY SSF55781 71 336 1.77E-67 T 14-10-2018 C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 Pfam PF01628 HrcA protein C terminal domain 104 322 3.0E-64 T 14-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 Gene3D G3DSA:3.30.450.40 104 333 1.0E-58 T 14-10-2018 IPR029016 GAF-like domain superfamily C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 Gene3D G3DSA:3.30.390.60 128 229 1.0E-58 T 14-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 SUPERFAMILY SSF46785 1 82 3.4E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 PIRSF PIRSF005485 1 338 3.7E-125 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 332 5.6E-114 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 Gene3D G3DSA:1.10.10.10 1 84 4.9E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17695 0a82df0cfea57ad9f6e4f025999d4f10 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 329 32.878 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 Gene3D G3DSA:3.50.50.60 114 440 5.0E-163 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 7.7E-28 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 7.7E-28 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 7.7E-28 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 7.7E-28 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 7.7E-28 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 294 2.0E-66 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 SUPERFAMILY SSF51905 3 316 5.74E-47 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 430 6.7E-15 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 SUPERFAMILY SSF55424 323 443 5.84E-34 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 Gene3D G3DSA:3.50.50.60 3 340 5.0E-163 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 3.1E-20 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 3.1E-20 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 3.1E-20 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 402 3.1E-20 T 14-10-2018 C2I25_05150 2f9d45657035c8ecf0d400f7a185db0f 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 3.1E-20 T 14-10-2018 C2I25_28005 ac76e0ecccdd64dd69268d98c9441c74 159 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 137 3.3E-25 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ C2I25_18925 79bf168260ab02e35781401253141adb 160 Pfam PF00583 Acetyltransferase (GNAT) family 21 118 1.1E-11 T 14-10-2018 IPR000182 GNAT domain C2I25_18925 79bf168260ab02e35781401253141adb 160 SUPERFAMILY SSF55729 1 126 6.97E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_18925 79bf168260ab02e35781401253141adb 160 Gene3D G3DSA:3.40.630.30 5 160 3.2E-21 T 14-10-2018 C2I25_20115 0d2b9211eb65059dcb717aca8162c188 174 Pfam PF04978 Protein of unknown function (DUF664) 18 164 6.6E-8 T 14-10-2018 IPR007061 Protein of unknown function DUF664 C2I25_20115 0d2b9211eb65059dcb717aca8162c188 174 Gene3D G3DSA:1.20.120.450 3 170 2.3E-41 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_20115 0d2b9211eb65059dcb717aca8162c188 174 SUPERFAMILY SSF109854 14 167 2.01E-34 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_22125 39ad862789d955e96367b1aee8461f74 327 SUPERFAMILY SSF51695 38 323 3.14E-44 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_22125 39ad862789d955e96367b1aee8461f74 327 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 44 187 9.1E-26 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I25_22125 39ad862789d955e96367b1aee8461f74 327 Gene3D G3DSA:3.20.20.190 24 250 4.3E-34 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_07460 8153c40a009ee6dd60664e77fcd831da 87 Pfam PF02583 Metal-sensitive transcriptional repressor 4 84 1.4E-25 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 C2I25_07460 8153c40a009ee6dd60664e77fcd831da 87 Gene3D G3DSA:1.20.58.1000 2 86 6.2E-24 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily C2I25_22560 50eee59e19998525c201e7443029e641 494 Gene3D G3DSA:2.130.10.10 351 494 2.4E-8 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_22560 50eee59e19998525c201e7443029e641 494 SUPERFAMILY SSF110296 99 488 4.97E-21 T 14-10-2018 C2I25_17865 27dd69a5fd7596ad447d94c0fdabc0a3 84 Pfam PF11116 Protein of unknown function (DUF2624) 1 82 4.3E-32 T 14-10-2018 IPR020277 Protein of unknown function DUF2624 C2I25_17865 27dd69a5fd7596ad447d94c0fdabc0a3 84 ProDom PD060869 YQFT IG BH1387 1 68 7.0E-31 T 14-10-2018 IPR020277 Protein of unknown function DUF2624 C2I25_08940 adf3519245bc9c09103204a3fc841559 337 Pfam PF00005 ABC transporter 42 185 2.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_08940 adf3519245bc9c09103204a3fc841559 337 SMART SM00382 50 234 8.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_08940 adf3519245bc9c09103204a3fc841559 337 Gene3D G3DSA:3.40.50.300 26 276 1.9E-60 T 14-10-2018 C2I25_08940 adf3519245bc9c09103204a3fc841559 337 SUPERFAMILY SSF52540 35 252 3.2E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07025 3958f94cf0254d7f72e377310376bf47 118 Hamap MF_01526 UPF0342 protein . 2 113 18.907 T 14-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA C2I25_07025 3958f94cf0254d7f72e377310376bf47 118 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 5 108 9.7E-23 T 14-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA C2I25_07025 3958f94cf0254d7f72e377310376bf47 118 SUPERFAMILY SSF158622 4 113 1.31E-34 T 14-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I25_07025 3958f94cf0254d7f72e377310376bf47 118 Gene3D G3DSA:1.20.1500.10 2 113 4.1E-35 T 14-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 Pfam PF00501 AMP-binding enzyme 32 435 1.5E-86 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 9.1E-14 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 Gene3D G3DSA:3.30.300.310 431 533 7.7E-31 T 14-10-2018 C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 Gene3D G3DSA:3.40.50.980 22 179 2.3E-54 T 14-10-2018 C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 Gene3D G3DSA:2.30.38.10 354 429 3.2E-31 T 14-10-2018 C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 SUPERFAMILY SSF56801 5 531 1.44E-139 T 14-10-2018 C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 4 526 1.2E-250 T 14-10-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 C2I25_28160 e7fa76de0a2b2ce9f0fd7e851dbe217e 538 Gene3D G3DSA:3.40.50.980 181 353 1.0E-60 T 14-10-2018 C2I25_23910 cc1c53ae0c29914d3bf1655816bfbbfa 346 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 4 333 2.0E-142 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 C2I25_23910 cc1c53ae0c29914d3bf1655816bfbbfa 346 PIRSF PIRSF005508 1 346 2.0E-140 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 C2I25_23910 cc1c53ae0c29914d3bf1655816bfbbfa 346 Pfam PF01758 Sodium Bile acid symporter family 49 245 3.3E-67 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 C2I25_23910 cc1c53ae0c29914d3bf1655816bfbbfa 346 Gene3D G3DSA:1.20.1530.20 1 339 1.0E-26 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily C2I25_23010 4bc0c547cbd73dc156cc7dc2634c4d17 182 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 109 161 6.3E-10 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_23010 4bc0c547cbd73dc156cc7dc2634c4d17 182 Hamap MF_01515 UPF0316 protein . 1 169 28.585 T 14-10-2018 IPR022930 Protein of unknown function UPF0316 C2I25_18080 78e832a195deb326a27c86e4db5c117e 80 Pfam PF11117 Protein of unknown function (DUF2626) 1 73 3.5E-38 T 14-10-2018 IPR020254 Protein of unknown function DUF2626 C2I25_18080 78e832a195deb326a27c86e4db5c117e 80 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 80 1.0E-38 T 14-10-2018 IPR020254 Protein of unknown function DUF2626 C2I25_14495 e24d8abbb086a62a8ebf369905fa7386 415 SUPERFAMILY SSF103473 20 409 2.49E-40 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_14495 e24d8abbb086a62a8ebf369905fa7386 415 Gene3D G3DSA:1.20.1250.20 17 211 8.5E-23 T 14-10-2018 C2I25_14495 e24d8abbb086a62a8ebf369905fa7386 415 Pfam PF07690 Major Facilitator Superfamily 27 364 1.9E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_14495 e24d8abbb086a62a8ebf369905fa7386 415 Gene3D G3DSA:1.20.1250.20 225 410 1.4E-9 T 14-10-2018 C2I25_02350 2964da680bbb1d40bbb903c3eaac7360 147 Gene3D G3DSA:3.40.630.30 1 136 1.5E-18 T 14-10-2018 C2I25_02350 2964da680bbb1d40bbb903c3eaac7360 147 SUPERFAMILY SSF55729 1 139 2.38E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_02350 2964da680bbb1d40bbb903c3eaac7360 147 Pfam PF13673 Acetyltransferase (GNAT) domain 41 129 7.3E-16 T 14-10-2018 IPR000182 GNAT domain C2I25_17830 5ddb0893946422373955f7d046eb6d1f 118 PIRSF PIRSF000025 1 118 5.5E-42 T 14-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 C2I25_17830 5ddb0893946422373955f7d046eb6d1f 118 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 47 114 3.4E-11 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_17830 5ddb0893946422373955f7d046eb6d1f 118 Gene3D G3DSA:1.10.760.10 49 118 2.7E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I25_17830 5ddb0893946422373955f7d046eb6d1f 118 SUPERFAMILY SSF46626 5 116 5.47E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 Pfam PF10415 Fumarase C C-terminus 410 463 7.7E-23 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 Gene3D G3DSA:1.10.40.30 410 461 7.4E-24 T 14-10-2018 C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 Gene3D G3DSA:1.20.200.10 142 409 4.6E-114 T 14-10-2018 C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 Gene3D G3DSA:1.10.275.10 8 141 2.0E-57 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 Pfam PF00206 Lyase 15 344 3.1E-111 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 8 468 2.5E-238 T 14-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 7.5E-6 T 14-10-2018 C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 7.5E-6 T 14-10-2018 C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 1.2E-31 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 1.2E-31 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 1.2E-31 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 1.2E-31 T 14-10-2018 IPR000362 Fumarate lyase family C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 SUPERFAMILY SSF48557 7 464 4.4E-148 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I25_08440 1abe2b57b0aa6a025726e597ed6abe06 477 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I25_17120 6964f428768359fb37e0187ccaed0084 380 Gene3D G3DSA:1.10.260.50 14 275 1.0E-120 T 14-10-2018 C2I25_17120 6964f428768359fb37e0187ccaed0084 380 Gene3D G3DSA:3.90.1150.10 3 367 1.0E-120 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_17120 6964f428768359fb37e0187ccaed0084 380 PIRSF PIRSF005572 1 376 1.0E-116 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I25_17120 6964f428768359fb37e0187ccaed0084 380 Gene3D G3DSA:3.40.640.10 60 232 1.0E-120 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_17120 6964f428768359fb37e0187ccaed0084 380 Pfam PF00266 Aminotransferase class-V 3 361 3.5E-72 T 14-10-2018 IPR000192 Aminotransferase class V domain C2I25_17120 6964f428768359fb37e0187ccaed0084 380 SUPERFAMILY SSF53383 2 370 2.6E-91 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_23035 e0d882e0bdee57e42a534b80bbc608d7 180 Gene3D G3DSA:1.10.3300.10 63 173 8.3E-12 T 14-10-2018 IPR023286 ABATE domain superfamily C2I25_23035 e0d882e0bdee57e42a534b80bbc608d7 180 SUPERFAMILY SSF160904 3 171 1.83E-30 T 14-10-2018 C2I25_23035 e0d882e0bdee57e42a534b80bbc608d7 180 Pfam PF11706 CGNR zinc finger 124 172 1.5E-19 T 14-10-2018 IPR021005 Zinc finger, CGNR C2I25_21915 a2875c681c7b979cc59d74517d9fd40a 306 SUPERFAMILY SSF54593 5 163 6.18E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21915 a2875c681c7b979cc59d74517d9fd40a 306 Gene3D G3DSA:3.10.180.10 12 174 4.6E-27 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21915 a2875c681c7b979cc59d74517d9fd40a 306 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 150 3.1E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_21915 a2875c681c7b979cc59d74517d9fd40a 306 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 191 301 9.1E-5 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_21915 a2875c681c7b979cc59d74517d9fd40a 306 Gene3D G3DSA:3.10.180.10 189 305 2.6E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21915 a2875c681c7b979cc59d74517d9fd40a 306 SUPERFAMILY SSF54593 189 301 1.33E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_05450 59038877d1194df950fb301fd0153a94 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.166 T 14-10-2018 IPR023731 Regulatory protein Spx GO:0045892 C2I25_05450 59038877d1194df950fb301fd0153a94 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 8.9E-35 T 14-10-2018 IPR006504 Transcriptional regulator Spx/MgsR C2I25_05450 59038877d1194df950fb301fd0153a94 131 Pfam PF03960 ArsC family 5 113 9.4E-21 T 14-10-2018 IPR006660 Arsenate reductase-like C2I25_05450 59038877d1194df950fb301fd0153a94 131 SUPERFAMILY SSF52833 1 129 3.3E-38 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_05450 59038877d1194df950fb301fd0153a94 131 Gene3D G3DSA:3.40.30.10 1 131 6.4E-45 T 14-10-2018 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 406 427 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 451 469 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 152 172 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 383 400 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 337 356 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 3.3E-81 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 Gene3D G3DSA:1.10.1370.30 3 505 5.1E-211 T 14-10-2018 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 2 499 7.6E-217 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 SUPERFAMILY SSF55486 7 499 6.7E-124 T 14-10-2018 C2I25_03570 6af6c4cd2519c5b16504588fe1b725e2 505 PIRSF PIRSF006615 4 505 1.3E-200 T 14-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I25_13615 ce46f51bb080d50b1ea94a907f0ebe1c 338 Pfam PF01032 FecCD transport family 36 330 1.7E-66 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_13615 ce46f51bb080d50b1ea94a907f0ebe1c 338 Gene3D G3DSA:1.10.3470.10 16 333 5.7E-63 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_13615 ce46f51bb080d50b1ea94a907f0ebe1c 338 SUPERFAMILY SSF81345 17 330 9.81E-66 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_00450 a479c69bd970a8981baee74942de5356 254 SMART SM00327 12 208 4.7E-4 T 14-10-2018 IPR002035 von Willebrand factor, type A C2I25_00450 a479c69bd970a8981baee74942de5356 254 Gene3D G3DSA:3.40.50.410 3 181 1.8E-10 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I25_00450 a479c69bd970a8981baee74942de5356 254 Pfam PF13519 von Willebrand factor type A domain 16 140 1.5E-7 T 14-10-2018 IPR002035 von Willebrand factor, type A C2I25_00450 a479c69bd970a8981baee74942de5356 254 SUPERFAMILY SSF53300 13 176 3.41E-12 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I25_15305 da91dd544aab69c490638f5d7ede0300 254 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_15305 da91dd544aab69c490638f5d7ede0300 254 Gene3D G3DSA:3.40.50.300 3 231 8.9E-64 T 14-10-2018 C2I25_15305 da91dd544aab69c490638f5d7ede0300 254 SMART SM00382 32 211 3.1E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_15305 da91dd544aab69c490638f5d7ede0300 254 SUPERFAMILY SSF52540 4 215 2.53E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_15305 da91dd544aab69c490638f5d7ede0300 254 Pfam PF00005 ABC transporter 23 162 2.7E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_18500 124d8803681d11b4b54c6678086e17f9 132 Gene3D G3DSA:1.10.10.10 11 123 4.4E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_18500 124d8803681d11b4b54c6678086e17f9 132 Pfam PF13730 Helix-turn-helix domain 35 85 6.1E-7 T 14-10-2018 C2I25_19705 c8929f88d22501678dcd2089f5ecd5ae 75 Pfam PF17259 Family of unknown function (DUF5325) 17 73 1.6E-19 T 14-10-2018 IPR035211 Protein of unknown function DUF5325 C2I25_19705 c8929f88d22501678dcd2089f5ecd5ae 75 ProDom PD699877 YLAF TRANSMEMBRANE MEMBRANE BH2633 17 72 1.0E-10 T 14-10-2018 IPR035211 Protein of unknown function DUF5325 C2I25_11980 fbe200215b66588eae6d93e1ba923fa7 143 Hamap MF_01141 Antiholin-like protein LrgA [lrgA]. 1 135 29.051 T 14-10-2018 IPR023736 Antiholin-like protein LrgA C2I25_11980 fbe200215b66588eae6d93e1ba923fa7 143 Pfam PF03788 LrgA family 21 112 2.8E-23 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 C2I25_27250 19f33d51fbee92ddfc7e8e7a2a01e207 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 61 2.8E-22 T 14-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I25_27250 19f33d51fbee92ddfc7e8e7a2a01e207 66 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 40 54 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_27250 19f33d51fbee92ddfc7e8e7a2a01e207 66 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 22 31 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_27250 19f33d51fbee92ddfc7e8e7a2a01e207 66 Gene3D G3DSA:1.10.8.910 8 66 2.7E-30 T 14-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I25_02275 fe3d4c32216d9fa38c33b9e979ce7098 402 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 54 231 2.9E-66 T 14-10-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 C2I25_02275 fe3d4c32216d9fa38c33b9e979ce7098 402 SUPERFAMILY SSF58100 45 390 2.56E-97 T 14-10-2018 C2I25_02275 fe3d4c32216d9fa38c33b9e979ce7098 402 Gene3D G3DSA:1.20.1170.10 59 397 1.8E-121 T 14-10-2018 C2I25_25735 70d7054d3137c988243cdbf794ec134c 200 Pfam PF13649 Methyltransferase domain 40 129 1.9E-13 T 14-10-2018 C2I25_25735 70d7054d3137c988243cdbf794ec134c 200 SUPERFAMILY SSF53335 3 171 4.97E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_25735 70d7054d3137c988243cdbf794ec134c 200 Gene3D G3DSA:3.40.50.150 4 199 1.3E-43 T 14-10-2018 C2I25_24745 22f3cd47e44d1d142b655b239401551c 522 Pfam PF08239 Bacterial SH3 domain 36 84 1.2E-10 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_24745 22f3cd47e44d1d142b655b239401551c 522 SMART SM00287 27 88 2.9E-11 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_24745 22f3cd47e44d1d142b655b239401551c 522 SMART SM00287 89 149 9.9E-5 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_24745 22f3cd47e44d1d142b655b239401551c 522 Gene3D G3DSA:2.30.30.40 87 146 5.4E-11 T 14-10-2018 C2I25_24745 22f3cd47e44d1d142b655b239401551c 522 Gene3D G3DSA:2.40.40.10 283 517 2.4E-8 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_24745 22f3cd47e44d1d142b655b239401551c 522 SUPERFAMILY SSF50685 460 512 1.15E-10 T 14-10-2018 IPR036908 RlpA-like domain superfamily C2I25_24745 22f3cd47e44d1d142b655b239401551c 522 Gene3D G3DSA:2.30.30.40 22 86 1.7E-16 T 14-10-2018 C2I25_24745 22f3cd47e44d1d142b655b239401551c 522 Pfam PF06725 3D domain 462 522 3.2E-21 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I25_22330 84ff16063ce5995fa834758bbebcca07 158 Pfam PF10901 Protein of unknown function (DUF2690) 35 139 6.8E-36 T 14-10-2018 IPR021224 Protein of unknown function DUF2690 C2I25_05640 b8b0e95f0fe1e24cc32db5a93de3308a 615 SUPERFAMILY SSF52402 231 576 3.93E-72 T 14-10-2018 C2I25_05640 b8b0e95f0fe1e24cc32db5a93de3308a 615 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.0E-45 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I25_05640 b8b0e95f0fe1e24cc32db5a93de3308a 615 PIRSF PIRSF001589 1 615 1.6E-141 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I25_05640 b8b0e95f0fe1e24cc32db5a93de3308a 615 Pfam PF00733 Asparagine synthase 243 582 8.8E-93 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 C2I25_05640 b8b0e95f0fe1e24cc32db5a93de3308a 615 Gene3D G3DSA:3.60.20.10 2 184 3.3E-63 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_05640 b8b0e95f0fe1e24cc32db5a93de3308a 615 SUPERFAMILY SSF56235 1 226 1.12E-65 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I25_05640 b8b0e95f0fe1e24cc32db5a93de3308a 615 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 5.3E-168 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I25_05325 e8168e1aa68f5550ef0f1fe0727c4b9d 245 SUPERFAMILY SSF53448 2 233 7.72E-68 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_05325 e8168e1aa68f5550ef0f1fe0727c4b9d 245 Pfam PF00483 Nucleotidyl transferase 2 231 1.1E-52 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I25_05325 e8168e1aa68f5550ef0f1fe0727c4b9d 245 Gene3D G3DSA:3.90.550.10 1 245 6.2E-74 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_28405 8d06ed162c6260f68aca97fac3f6d143 251 Pfam PF07070 SpoOM protein 2 211 1.1E-75 T 14-10-2018 IPR009776 Sporulation stage 0, protein M C2I25_04620 ae7976f54eeb1442161f284b72458b5e 258 Pfam PF12730 ABC-2 family transporter protein 4 182 1.2E-35 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I25_26030 72889c595bc5272fff14ae2ceb19258a 476 SUPERFAMILY SSF50952 73 321 1.14E-11 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 C2I25_26030 72889c595bc5272fff14ae2ceb19258a 476 Pfam PF07995 Glucose / Sorbosone dehydrogenase 77 277 5.6E-11 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase C2I25_26030 72889c595bc5272fff14ae2ceb19258a 476 Gene3D G3DSA:2.120.10.30 3 422 8.7E-27 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I25_11435 acabdc58918924bc0667a13f0a653e58 96 SMART SM00465 5 83 0.0017 T 14-10-2018 IPR000305 GIY-YIG endonuclease C2I25_11435 acabdc58918924bc0667a13f0a653e58 96 SUPERFAMILY SSF82771 5 76 1.31E-12 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I25_11435 acabdc58918924bc0667a13f0a653e58 96 Gene3D G3DSA:3.40.1440.10 1 96 4.7E-31 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I25_11435 acabdc58918924bc0667a13f0a653e58 96 Pfam PF01541 GIY-YIG catalytic domain 5 77 9.3E-16 T 14-10-2018 IPR000305 GIY-YIG endonuclease C2I25_06885 c3b9611df73ced17df2b8adf8b8e1487 334 Gene3D G3DSA:3.10.310.10 146 310 9.8E-128 T 14-10-2018 C2I25_06885 c3b9611df73ced17df2b8adf8b8e1487 334 PIRSF PIRSF029792 1 334 3.2E-136 T 14-10-2018 IPR008794 Proline racemase family C2I25_06885 c3b9611df73ced17df2b8adf8b8e1487 334 Pfam PF05544 Proline racemase 10 331 4.5E-105 T 14-10-2018 IPR008794 Proline racemase family C2I25_06885 c3b9611df73ced17df2b8adf8b8e1487 334 SUPERFAMILY SSF54506 1 331 1.35E-106 T 14-10-2018 C2I25_06885 c3b9611df73ced17df2b8adf8b8e1487 334 Gene3D G3DSA:3.10.310.10 8 333 9.8E-128 T 14-10-2018 C2I25_06190 32fd965362aa6621fe2c41b9e107a9e2 185 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I25_06190 32fd965362aa6621fe2c41b9e107a9e2 185 Gene3D G3DSA:1.10.10.10 2 167 8.9E-44 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_06190 32fd965362aa6621fe2c41b9e107a9e2 185 Pfam PF01047 MarR family 44 101 1.2E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_06190 32fd965362aa6621fe2c41b9e107a9e2 185 SUPERFAMILY SSF46785 19 130 4.07E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_06190 32fd965362aa6621fe2c41b9e107a9e2 185 SMART SM00347 37 137 1.5E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_06190 32fd965362aa6621fe2c41b9e107a9e2 185 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 2 185 49.756 T 14-10-2018 IPR023488 HTH-type transcriptional regulator Hpr C2I25_19060 e36ebdf84e59eff960b1fa26018d5ea1 357 Pfam PF12730 ABC-2 family transporter protein 13 186 4.9E-10 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I25_06870 07e34493d8e6475754a4493c58301efd 528 PIRSF PIRSF002741 1 524 1.1E-118 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_06870 07e34493d8e6475754a4493c58301efd 528 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 89 111 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site C2I25_06870 07e34493d8e6475754a4493c58301efd 528 Gene3D G3DSA:3.90.76.10 73 191 3.7E-153 T 14-10-2018 C2I25_06870 07e34493d8e6475754a4493c58301efd 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 445 4.8E-83 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_06870 07e34493d8e6475754a4493c58301efd 528 Gene3D G3DSA:3.40.190.10 47 500 3.7E-153 T 14-10-2018 C2I25_06870 07e34493d8e6475754a4493c58301efd 528 Gene3D G3DSA:3.10.105.10 283 493 3.7E-153 T 14-10-2018 C2I25_06870 07e34493d8e6475754a4493c58301efd 528 SUPERFAMILY SSF53850 38 518 1.71E-123 T 14-10-2018 C2I25_02315 8ddce11ed20bb481dd3f593860231dd0 286 Pfam PF01551 Peptidase family M23 158 250 2.0E-15 T 14-10-2018 IPR016047 Peptidase M23 C2I25_02315 8ddce11ed20bb481dd3f593860231dd0 286 Gene3D G3DSA:2.70.70.10 126 268 1.4E-21 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_02315 8ddce11ed20bb481dd3f593860231dd0 286 SUPERFAMILY SSF51261 149 252 1.99E-17 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_02590 e0c68f0d019d8c1463068ee9df61ff4f 44 Pfam PF13070 Protein of unknown function (DUF3934) 1 42 2.6E-21 T 14-10-2018 IPR025175 Protein of unknown function DUF3934 C2I25_08270 3fdc8835ec79580f4632de9569ae0c65 144 PRINTS PR00332 Histidine triad family signature 90 100 3.2E-7 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_08270 3fdc8835ec79580f4632de9569ae0c65 144 PRINTS PR00332 Histidine triad family signature 25 43 3.2E-7 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_08270 3fdc8835ec79580f4632de9569ae0c65 144 PRINTS PR00332 Histidine triad family signature 4 20 3.2E-7 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_08270 3fdc8835ec79580f4632de9569ae0c65 144 SUPERFAMILY SSF54197 1 113 1.16E-33 T 14-10-2018 IPR036265 HIT-like superfamily C2I25_08270 3fdc8835ec79580f4632de9569ae0c65 144 Gene3D G3DSA:3.30.428.10 1 142 7.7E-35 T 14-10-2018 IPR036265 HIT-like superfamily C2I25_08270 3fdc8835ec79580f4632de9569ae0c65 144 Pfam PF01230 HIT domain 13 104 6.4E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein C2I25_23485 b4c1c7f41b36b5daecf8293a5c1f4c6f 343 SUPERFAMILY SSF52317 2 170 9.15E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_23485 b4c1c7f41b36b5daecf8293a5c1f4c6f 343 Gene3D G3DSA:3.40.50.10740 1 165 9.0E-66 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal C2I25_23485 b4c1c7f41b36b5daecf8293a5c1f4c6f 343 SUPERFAMILY SSF141986 173 334 4.05E-27 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I25_23485 b4c1c7f41b36b5daecf8293a5c1f4c6f 343 PIRSF PIRSF028757 2 343 5.6E-67 T 14-10-2018 IPR003507 Peptidase family S66 C2I25_23485 b4c1c7f41b36b5daecf8293a5c1f4c6f 343 Pfam PF02016 LD-carboxypeptidase 14 328 8.5E-72 T 14-10-2018 IPR003507 Peptidase family S66 C2I25_23485 b4c1c7f41b36b5daecf8293a5c1f4c6f 343 Gene3D G3DSA:3.50.30.60 166 343 7.6E-63 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I25_01855 ac855af9afefd8ddcd2886a9b9e1b427 200 Gene3D G3DSA:3.40.109.10 3 200 1.4E-90 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_01855 ac855af9afefd8ddcd2886a9b9e1b427 200 SUPERFAMILY SSF55469 5 199 1.31E-72 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_01855 ac855af9afefd8ddcd2886a9b9e1b427 200 Pfam PF00881 Nitroreductase family 10 179 1.5E-19 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_09995 a00553006ec62c06bb76a1797f49fe7a 314 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 300 1.9E-38 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_09995 a00553006ec62c06bb76a1797f49fe7a 314 Gene3D G3DSA:3.40.50.720 7 239 1.8E-74 T 14-10-2018 C2I25_09995 a00553006ec62c06bb76a1797f49fe7a 314 SUPERFAMILY SSF51735 2 309 1.07E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_09995 a00553006ec62c06bb76a1797f49fe7a 314 Gene3D G3DSA:3.90.25.10 174 300 1.8E-74 T 14-10-2018 C2I25_04255 8ea5624c5dd50381e6e34eca85d81e8e 452 Pfam PF00209 Sodium:neurotransmitter symporter family 6 123 2.7E-24 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_04255 8ea5624c5dd50381e6e34eca85d81e8e 452 Pfam PF00209 Sodium:neurotransmitter symporter family 150 446 9.1E-29 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_04255 8ea5624c5dd50381e6e34eca85d81e8e 452 SUPERFAMILY SSF161070 7 445 1.7E-129 T 14-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 C2I25_04255 8ea5624c5dd50381e6e34eca85d81e8e 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 5.8E-11 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_04255 8ea5624c5dd50381e6e34eca85d81e8e 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 298 317 5.8E-11 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_04255 8ea5624c5dd50381e6e34eca85d81e8e 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 5.8E-11 T 14-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I25_15525 d32a5077eb62002472e3cbde259b7908 253 Gene3D G3DSA:3.40.50.300 3 251 6.1E-66 T 14-10-2018 C2I25_15525 d32a5077eb62002472e3cbde259b7908 253 SMART SM00382 35 234 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_15525 d32a5077eb62002472e3cbde259b7908 253 Pfam PF00005 ABC transporter 26 174 1.8E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_15525 d32a5077eb62002472e3cbde259b7908 253 SUPERFAMILY SSF52540 6 227 2.3E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07190 dc0849b0f3f376c1518861e7c108d3d2 303 SUPERFAMILY SSF103481 189 286 5.75E-16 T 14-10-2018 C2I25_07190 dc0849b0f3f376c1518861e7c108d3d2 303 SUPERFAMILY SSF103481 38 140 2.35E-18 T 14-10-2018 C2I25_07190 dc0849b0f3f376c1518861e7c108d3d2 303 Pfam PF00892 EamA-like transporter family 152 284 1.5E-29 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_07190 dc0849b0f3f376c1518861e7c108d3d2 303 Pfam PF00892 EamA-like transporter family 5 137 3.3E-29 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_19870 eeafabc7575ee3d401d7b42ad1f43cf5 408 Hamap MF_01539 UPF0348 protein . 1 399 39.808 T 14-10-2018 IPR008513 Uncharacterised protein family UPF0348 C2I25_19870 eeafabc7575ee3d401d7b42ad1f43cf5 408 Pfam PF05636 HIGH Nucleotidyl Transferase 1 382 3.9E-136 T 14-10-2018 IPR008513 Uncharacterised protein family UPF0348 C2I25_19870 eeafabc7575ee3d401d7b42ad1f43cf5 408 Gene3D G3DSA:3.40.50.620 1 239 5.7E-40 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_19870 eeafabc7575ee3d401d7b42ad1f43cf5 408 SUPERFAMILY SSF52374 5 233 1.9E-17 T 14-10-2018 C2I25_18090 0e1981d04aa4aa581dcf853d080a7e30 347 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 204 218 - T 14-10-2018 IPR001482 Type II/IV secretion system protein C2I25_18090 0e1981d04aa4aa581dcf853d080a7e30 347 Pfam PF00437 Type II/IV secretion system protein 12 275 1.8E-70 T 14-10-2018 IPR001482 Type II/IV secretion system protein C2I25_18090 0e1981d04aa4aa581dcf853d080a7e30 347 Gene3D G3DSA:3.40.50.300 110 337 8.9E-67 T 14-10-2018 C2I25_18090 0e1981d04aa4aa581dcf853d080a7e30 347 Gene3D G3DSA:3.30.450.90 2 108 1.1E-27 T 14-10-2018 C2I25_18090 0e1981d04aa4aa581dcf853d080a7e30 347 SMART SM00382 136 265 8.6E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_18090 0e1981d04aa4aa581dcf853d080a7e30 347 SUPERFAMILY SSF52540 5 283 1.67E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_11810 e477346b3aad0170e55aeb67f6f5b225 61 Pfam PF14116 YyzF-like protein 5 52 9.8E-21 T 14-10-2018 IPR025626 YyzF-like protein C2I25_11810 e477346b3aad0170e55aeb67f6f5b225 61 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 4 51 3.2E-20 T 14-10-2018 IPR025626 YyzF-like protein C2I25_08215 40268bc94cc00d7a0317f530de532c0a 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 292 5.6E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_08215 40268bc94cc00d7a0317f530de532c0a 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 71 2.0E-7 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I25_08215 40268bc94cc00d7a0317f530de532c0a 301 Gene3D G3DSA:1.10.3720.10 88 296 3.5E-18 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_08215 40268bc94cc00d7a0317f530de532c0a 301 SUPERFAMILY SSF161098 90 284 1.96E-21 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_19010 90553f70a33194de309ae054f3e79e86 246 Pfam PF13115 YtkA-like 30 112 2.1E-15 T 14-10-2018 IPR032693 YtkA-like domain C2I25_19010 90553f70a33194de309ae054f3e79e86 246 Pfam PF13115 YtkA-like 156 229 1.2E-10 T 14-10-2018 IPR032693 YtkA-like domain C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 Pfam PF13416 Bacterial extracellular solute-binding protein 56 357 3.9E-57 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 SUPERFAMILY SSF53850 42 407 3.78E-93 T 14-10-2018 C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 Gene3D G3DSA:3.40.190.10 147 403 2.1E-116 T 14-10-2018 C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 Gene3D G3DSA:3.40.190.10 59 370 2.1E-116 T 14-10-2018 C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 138 157 1.7E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 245 264 1.7E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 159 178 1.7E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 78 96 1.7E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 C2I25_19415 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 370 389 1.7E-7 T 14-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 C2I25_22205 126484bf0f4fa5167f1c54c64bbf77ca 114 SUPERFAMILY SSF46785 17 99 4.49E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_22205 126484bf0f4fa5167f1c54c64bbf77ca 114 Gene3D G3DSA:1.10.10.10 2 111 9.7E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22205 126484bf0f4fa5167f1c54c64bbf77ca 114 SMART SM00418 22 101 3.0E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22205 126484bf0f4fa5167f1c54c64bbf77ca 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 9.0E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22205 126484bf0f4fa5167f1c54c64bbf77ca 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 9.0E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22205 126484bf0f4fa5167f1c54c64bbf77ca 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 9.0E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_22205 126484bf0f4fa5167f1c54c64bbf77ca 114 Pfam PF01022 Bacterial regulatory protein, arsR family 29 77 9.7E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_05130 c068a4f57d7f2ae7d08dbe5bf46c630e 649 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 266 649 3.6E-142 T 14-10-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component C2I25_05130 c068a4f57d7f2ae7d08dbe5bf46c630e 649 Gene3D G3DSA:2.40.50.820 296 375 3.9E-47 T 14-10-2018 C2I25_05130 c068a4f57d7f2ae7d08dbe5bf46c630e 649 Gene3D G3DSA:1.10.490.140 274 605 3.9E-47 T 14-10-2018 C2I25_05130 c068a4f57d7f2ae7d08dbe5bf46c630e 649 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 68 237 3.1E-43 T 14-10-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain C2I25_05130 c068a4f57d7f2ae7d08dbe5bf46c630e 649 Gene3D G3DSA:3.40.50.720 23 189 1.4E-25 T 14-10-2018 C2I25_05130 c068a4f57d7f2ae7d08dbe5bf46c630e 649 SUPERFAMILY SSF69572 54 223 1.71E-7 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I25_05130 c068a4f57d7f2ae7d08dbe5bf46c630e 649 Gene3D G3DSA:3.30.160.660 412 551 3.9E-47 T 14-10-2018 C2I25_05130 c068a4f57d7f2ae7d08dbe5bf46c630e 649 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 266 604 5.7E-88 T 14-10-2018 IPR003776 YcaO-like domain C2I25_04240 91dd6f84f3299691514f13e1cb07e576 172 Gene3D G3DSA:2.40.380.10 46 165 8.9E-10 T 14-10-2018 IPR035930 FomD-like superfamily C2I25_04240 91dd6f84f3299691514f13e1cb07e576 172 Pfam PF04167 Protein of unknown function (DUF402) 57 125 6.1E-17 T 14-10-2018 IPR007295 Domain of unknown function DUF402 C2I25_04240 91dd6f84f3299691514f13e1cb07e576 172 SUPERFAMILY SSF159234 1 166 1.31E-39 T 14-10-2018 IPR035930 FomD-like superfamily C2I25_26500 040b3ed2557a3dcb8eb3765005d47a9b 138 Pfam PF13160 Protein of unknown function (DUF3995) 12 132 4.0E-36 T 14-10-2018 IPR025058 Protein of unknown function DUF3995 C2I25_04845 c620dac030819b04188061aeb74f469c 160 TIGRFAM TIGR02132 phaR_Bmeg: polyhydroxyalkanoic acid synthase, PhaR subunit 2 135 1.4E-76 T 14-10-2018 IPR011729 Polyhydroxyalkanoic acid synthase, PhaR subunit C2I25_16620 f01816b0b408d40dbe4cfa0455db5c9a 64 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 63 7.5E-37 T 14-10-2018 IPR019240 Protein of unknown function DUF2196 C2I25_16620 f01816b0b408d40dbe4cfa0455db5c9a 64 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 3.2E-34 T 14-10-2018 IPR019240 Protein of unknown function DUF2196 C2I25_02180 4e44e1d3d808645ccea223309076d951 235 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 3.3E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_02180 4e44e1d3d808645ccea223309076d951 235 PRINTS PR00111 Alpha/beta hydrolase fold signature 182 196 3.3E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_02180 4e44e1d3d808645ccea223309076d951 235 PRINTS PR00111 Alpha/beta hydrolase fold signature 28 43 3.3E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_02180 4e44e1d3d808645ccea223309076d951 235 PRINTS PR00111 Alpha/beta hydrolase fold signature 71 84 3.3E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_02180 4e44e1d3d808645ccea223309076d951 235 Pfam PF12697 Alpha/beta hydrolase family 5 228 1.8E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_02180 4e44e1d3d808645ccea223309076d951 235 SUPERFAMILY SSF53474 5 233 4.09E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_02180 4e44e1d3d808645ccea223309076d951 235 Gene3D G3DSA:3.40.50.1820 2 235 3.3E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_25720 59f2e98f085fbb6a3c83cf352093f40e 198 Gene3D G3DSA:2.60.20.10 108 198 4.6E-10 T 14-10-2018 C2I25_20590 d6b5271170a540820bd843027197a0fd 82 Gene3D G3DSA:1.10.760.20 1 82 4.3E-30 T 14-10-2018 IPR038292 YmfJ/YflH superfamily C2I25_20590 d6b5271170a540820bd843027197a0fd 82 PIRSF PIRSF004764 1 82 1.3E-24 T 14-10-2018 IPR024702 Uncharacterised conserved protein YmfJ C2I25_20590 d6b5271170a540820bd843027197a0fd 82 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 8.9E-33 T 14-10-2018 IPR021637 Protein of unknown function DUF3243 C2I25_14670 baa3968521f1748b9bc017f8d48b08c1 226 Pfam PF02308 MgtC family 10 134 5.7E-33 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_14670 baa3968521f1748b9bc017f8d48b08c1 226 PRINTS PR01837 MgtC/SapB protein signature 66 88 3.0E-40 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_14670 baa3968521f1748b9bc017f8d48b08c1 226 PRINTS PR01837 MgtC/SapB protein signature 13 32 3.0E-40 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_14670 baa3968521f1748b9bc017f8d48b08c1 226 PRINTS PR01837 MgtC/SapB protein signature 94 118 3.0E-40 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_14670 baa3968521f1748b9bc017f8d48b08c1 226 PRINTS PR01837 MgtC/SapB protein signature 32 50 3.0E-40 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_12035 39ff5cb7e700f24c43b146a3b45e4f6d 326 Gene3D G3DSA:3.90.550.10 1 250 1.9E-68 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_12035 39ff5cb7e700f24c43b146a3b45e4f6d 326 Pfam PF00535 Glycosyl transferase family 2 9 139 4.3E-38 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_12035 39ff5cb7e700f24c43b146a3b45e4f6d 326 SUPERFAMILY SSF53448 7 226 1.09E-64 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_21865 779fa8aa61158212cc7114284be954ae 131 SUPERFAMILY SSF55811 5 118 1.06E-20 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_21865 779fa8aa61158212cc7114284be954ae 131 Gene3D G3DSA:3.90.79.10 1 127 2.7E-21 T 14-10-2018 C2I25_21865 779fa8aa61158212cc7114284be954ae 131 PRINTS PR00502 NUDIX hydrolase family signature 29 43 1.8E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_21865 779fa8aa61158212cc7114284be954ae 131 PRINTS PR00502 NUDIX hydrolase family signature 43 58 1.8E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_21865 779fa8aa61158212cc7114284be954ae 131 Pfam PF00293 NUDIX domain 4 111 3.2E-13 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_20085 d83ced94cb804683c5224b5241a7e83e 210 Pfam PF00156 Phosphoribosyl transferase domain 44 155 3.6E-19 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_20085 d83ced94cb804683c5224b5241a7e83e 210 Gene3D G3DSA:3.40.50.2020 1 210 6.2E-68 T 14-10-2018 C2I25_20085 d83ced94cb804683c5224b5241a7e83e 210 SUPERFAMILY SSF53271 2 203 6.95E-52 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_20085 d83ced94cb804683c5224b5241a7e83e 210 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 8 175 1.3E-49 T 14-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_20085 d83ced94cb804683c5224b5241a7e83e 210 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 210 30.289 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I25_07735 d126f168574c58b09a5a1a44f14e6cc9 249 SUPERFAMILY SSF52540 6 222 8.99E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_07735 d126f168574c58b09a5a1a44f14e6cc9 249 Pfam PF00005 ABC transporter 23 157 2.3E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_07735 d126f168574c58b09a5a1a44f14e6cc9 249 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_07735 d126f168574c58b09a5a1a44f14e6cc9 249 SMART SM00382 31 207 2.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_07735 d126f168574c58b09a5a1a44f14e6cc9 249 Gene3D G3DSA:3.40.50.300 1 227 8.5E-57 T 14-10-2018 C2I25_04455 9975ddf4a538db223d44e02bbe740c43 139 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 34 131 2.4E-25 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_04455 9975ddf4a538db223d44e02bbe740c43 139 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 6 135 2.5E-46 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_04455 9975ddf4a538db223d44e02bbe740c43 139 PIRSF PIRSF021377 4 138 1.4E-47 T 14-10-2018 IPR014229 Sporulation protein YtfJ C2I25_00925 97871d23fa75da6293174c5bfeab0e87 91 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 4 87 4.0E-28 T 14-10-2018 IPR007347 Sporulation stage V, protein S C2I25_00925 97871d23fa75da6293174c5bfeab0e87 91 Pfam PF04232 Stage V sporulation protein S (SpoVS) 4 84 2.3E-39 T 14-10-2018 IPR007347 Sporulation stage V, protein S C2I25_00925 97871d23fa75da6293174c5bfeab0e87 91 Gene3D G3DSA:3.30.110.20 1 88 9.9E-35 T 14-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 C2I25_04940 0eb8da5610435804e19a218d2d3eec7b 442 SUPERFAMILY SSF46548 9 105 2.22E-19 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I25_04940 0eb8da5610435804e19a218d2d3eec7b 442 Pfam PF02754 Cysteine-rich domain 328 413 8.3E-14 T 14-10-2018 IPR004017 Cysteine-rich domain C2I25_04940 0eb8da5610435804e19a218d2d3eec7b 442 Pfam PF02754 Cysteine-rich domain 197 277 2.1E-19 T 14-10-2018 IPR004017 Cysteine-rich domain C2I25_04940 0eb8da5610435804e19a218d2d3eec7b 442 Gene3D G3DSA:1.10.1060.10 2 112 2.5E-8 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I25_04940 0eb8da5610435804e19a218d2d3eec7b 442 PIRSF PIRSF000139 5 441 1.8E-161 T 14-10-2018 C2I25_04940 0eb8da5610435804e19a218d2d3eec7b 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I25_04940 0eb8da5610435804e19a218d2d3eec7b 442 Pfam PF13183 4Fe-4S dicluster domain 22 91 1.9E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I25_09805 683e234e96145b7cba21c19232636dcc 221 Gene3D G3DSA:1.10.3720.10 9 217 1.8E-42 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_09805 683e234e96145b7cba21c19232636dcc 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 214 9.0E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_09805 683e234e96145b7cba21c19232636dcc 221 SUPERFAMILY SSF161098 9 205 4.45E-41 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05205 d809a9e0704678071e6d7c04bac22f73 204 Gene3D G3DSA:3.20.20.70 1 202 1.9E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_05205 d809a9e0704678071e6d7c04bac22f73 204 SUPERFAMILY SSF51366 1 199 4.55E-55 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I25_05205 d809a9e0704678071e6d7c04bac22f73 204 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 196 4.4E-51 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 C2I25_05205 d809a9e0704678071e6d7c04bac22f73 204 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 202 39.043 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 C2I25_22845 a9dabed024bf21fe2cfe142b90837cc2 105 Gene3D G3DSA:1.10.10.10 3 105 8.2E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22845 a9dabed024bf21fe2cfe142b90837cc2 105 Pfam PF01638 HxlR-like helix-turn-helix 18 103 4.3E-27 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_22845 a9dabed024bf21fe2cfe142b90837cc2 105 SUPERFAMILY SSF46785 6 101 5.66E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01540 7209c94660a2f965c65506b1d35a21df 314 Gene3D G3DSA:3.40.50.1820 104 310 1.6E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_01540 7209c94660a2f965c65506b1d35a21df 314 SUPERFAMILY SSF53474 122 305 1.08E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_01540 7209c94660a2f965c65506b1d35a21df 314 Pfam PF02230 Phospholipase/Carboxylesterase 194 296 1.1E-6 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 C2I25_02855 e6a484f45366241da51aa6693dd7f03a 275 Pfam PF13672 Protein phosphatase 2C 126 238 6.2E-8 T 14-10-2018 C2I25_02855 e6a484f45366241da51aa6693dd7f03a 275 SUPERFAMILY SSF81606 101 237 2.49E-6 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_05645 30bae06c35c8b64c7ed4c37de36e544f 184 Pfam PF10949 Protein of unknown function (DUF2777) 3 182 1.0E-70 T 14-10-2018 IPR024488 Protein of unknown function DUF2777 C2I25_05645 30bae06c35c8b64c7ed4c37de36e544f 184 ProDom PD106196 YISN IG BH1722 3 177 1.0E-99 T 14-10-2018 IPR024488 Protein of unknown function DUF2777 C2I25_05295 6004ae7e72a75a12931b235cc3c45030 154 Pfam PF10612 Spore coat protein Z 1 149 8.5E-46 T 14-10-2018 IPR019593 Spore coat protein Z/Y C2I25_08120 9ad8d696e9058be5123dd3ef1f277e67 114 Pfam PF07885 Ion channel 30 99 7.7E-20 T 14-10-2018 IPR013099 Potassium channel domain C2I25_08120 9ad8d696e9058be5123dd3ef1f277e67 114 Gene3D G3DSA:1.10.287.70 1 114 1.6E-47 T 14-10-2018 C2I25_08120 9ad8d696e9058be5123dd3ef1f277e67 114 SUPERFAMILY SSF81324 7 106 3.14E-22 T 14-10-2018 C2I25_15460 5715cdc6dfe600fa40a2c0e5b6d7b248 358 Pfam PF10776 Protein of unknown function (DUF2600) 24 353 2.0E-153 T 14-10-2018 IPR019712 Protein of unknown function DUF2600 C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 SUPERFAMILY SSF53850 91 288 6.67E-34 T 14-10-2018 C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.9E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Gene3D G3DSA:3.40.190.290 92 287 1.5E-39 T 14-10-2018 C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Pfam PF03466 LysR substrate binding domain 88 285 1.2E-36 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 SUPERFAMILY SSF46785 1 111 2.04E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02030 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Gene3D G3DSA:1.10.10.10 1 84 5.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_11900 a452a8883bdb90488401b4d46651c3fa 191 Pfam PF08006 Protein of unknown function (DUF1700) 5 188 5.2E-46 T 14-10-2018 IPR012963 Protein of unknown function DUF1700 C2I25_06295 cf4c6d7987f5c0df6a816ebb876153db 283 Pfam PF11155 Domain of unknown function (DUF2935) 151 267 1.8E-31 T 14-10-2018 IPR021328 Protein of unknown function DUF2935 C2I25_06295 cf4c6d7987f5c0df6a816ebb876153db 283 Pfam PF11155 Domain of unknown function (DUF2935) 22 136 4.8E-32 T 14-10-2018 IPR021328 Protein of unknown function DUF2935 C2I25_06295 cf4c6d7987f5c0df6a816ebb876153db 283 Gene3D G3DSA:1.20.1260.120 8 283 5.4E-126 T 14-10-2018 C2I25_06295 cf4c6d7987f5c0df6a816ebb876153db 283 SUPERFAMILY SSF158430 148 271 1.2E-38 T 14-10-2018 C2I25_06295 cf4c6d7987f5c0df6a816ebb876153db 283 SUPERFAMILY SSF158430 15 142 2.35E-39 T 14-10-2018 C2I25_24975 6ddfe84567da91d7e1101d67113b58fc 370 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 347 3.6E-190 T 14-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 C2I25_24975 6ddfe84567da91d7e1101d67113b58fc 370 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 1 370 77.325 T 14-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 C2I25_24975 6ddfe84567da91d7e1101d67113b58fc 370 SUPERFAMILY SSF51679 1 349 2.09E-100 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_24975 6ddfe84567da91d7e1101d67113b58fc 370 Gene3D G3DSA:3.20.20.30 1 358 2.7E-146 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_24975 6ddfe84567da91d7e1101d67113b58fc 370 Pfam PF00296 Luciferase-like monooxygenase 1 323 7.9E-92 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I25_08065 9466908da09ff067631a7721698c23c7 75 SUPERFAMILY SSF47413 4 70 1.02E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_08065 9466908da09ff067631a7721698c23c7 75 Gene3D G3DSA:1.10.260.40 5 70 1.6E-23 T 14-10-2018 C2I25_08065 9466908da09ff067631a7721698c23c7 75 Pfam PF01381 Helix-turn-helix 10 63 1.3E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_08065 9466908da09ff067631a7721698c23c7 75 SMART SM00530 9 64 7.2E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_03535 b59e7304bcd1705e3d5bbe6369922799 1219 Gene3D G3DSA:3.40.50.300 46 278 5.2E-41 T 14-10-2018 C2I25_03535 b59e7304bcd1705e3d5bbe6369922799 1219 SUPERFAMILY SSF52540 607 899 1.06E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03535 b59e7304bcd1705e3d5bbe6369922799 1219 SUPERFAMILY SSF52540 32 242 4.83E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03535 b59e7304bcd1705e3d5bbe6369922799 1219 Pfam PF00350 Dynamin family 46 200 2.3E-30 T 14-10-2018 IPR022812 Dynamin superfamily C2I25_03535 b59e7304bcd1705e3d5bbe6369922799 1219 Pfam PF00350 Dynamin family 624 850 9.5E-47 T 14-10-2018 IPR022812 Dynamin superfamily C2I25_03020 7c59017f6d44d89aa4c60921ced07616 253 Pfam PF01311 Bacterial export proteins, family 1 8 237 2.5E-48 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I25_03020 7c59017f6d44d89aa4c60921ced07616 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 72 91 5.5E-14 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I25_03020 7c59017f6d44d89aa4c60921ced07616 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 194 213 5.5E-14 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I25_03020 7c59017f6d44d89aa4c60921ced07616 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 172 194 5.5E-14 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I25_03020 7c59017f6d44d89aa4c60921ced07616 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 15 36 5.5E-14 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I25_18960 e6e9c491f71d5968d7c0c9ccbbf24c95 174 Pfam PF04229 GrpB protein 4 162 6.8E-53 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase C2I25_18960 e6e9c491f71d5968d7c0c9ccbbf24c95 174 Gene3D G3DSA:3.30.460.10 1 169 1.7E-54 T 14-10-2018 C2I25_18960 e6e9c491f71d5968d7c0c9ccbbf24c95 174 SUPERFAMILY SSF81301 5 169 3.27E-51 T 14-10-2018 C2I25_20005 fdb4e4e7cb446b6af2b7f84d043f88b8 87 Pfam PF02325 YGGT family 11 77 1.9E-24 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 C2I25_20745 efb33b5bccab6af477ce482c05bed364 223 Pfam PF04172 LrgB-like family 7 217 4.8E-62 T 14-10-2018 IPR007300 CidB/LrgB family C2I25_15545 fa18074ac8ea55db0a094d7e1b22998e 407 Pfam PF00999 Sodium/hydrogen exchanger family 12 374 1.8E-59 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I25_15545 fa18074ac8ea55db0a094d7e1b22998e 407 Gene3D G3DSA:1.20.1530.20 2 384 3.0E-67 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily C2I25_13440 81109cc4a617f193e766470d3bb06510 268 Pfam PF04018 Domain of unknown function (DUF368) 12 239 1.6E-53 T 14-10-2018 IPR007163 Protein of unknown function DUF368 C2I25_12015 12f8aff3f8345ba7402cdb0095db1844 127 Pfam PF04138 GtrA-like protein 6 119 8.7E-30 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 C2I25_28120 6f2c7d9f11c4c690a01accacdcdfef6a 255 Pfam PF13030 Protein of unknown function (DUF3891) 1 229 7.2E-65 T 14-10-2018 IPR024992 Protein of unknown function DUF3891 C2I25_01420 24cdfb62fcc445bcb1051c085139e191 298 Pfam PF03773 Predicted permease 11 293 8.5E-80 T 14-10-2018 IPR005524 Predicted permease DUF318 C2I25_23090 6a33794bb035c9cb61e1af2038a04249 397 Pfam PF07690 Major Facilitator Superfamily 240 387 3.6E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_23090 6a33794bb035c9cb61e1af2038a04249 397 SUPERFAMILY SSF103473 20 392 2.62E-36 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_23090 6a33794bb035c9cb61e1af2038a04249 397 Gene3D G3DSA:1.20.1250.20 207 393 1.4E-19 T 14-10-2018 C2I25_23090 6a33794bb035c9cb61e1af2038a04249 397 Gene3D G3DSA:1.20.1250.20 18 202 2.8E-11 T 14-10-2018 C2I25_21530 1b16378dfcc3ee99b5a1e0bb990eff9b 96 PIRSF PIRSF034852 1 96 6.6E-41 T 14-10-2018 IPR008326 Uncharacterised conserved protein UCP034852 C2I25_21530 1b16378dfcc3ee99b5a1e0bb990eff9b 96 SUPERFAMILY SSF89360 1 79 1.44E-11 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I25_21530 1b16378dfcc3ee99b5a1e0bb990eff9b 96 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 81 5.2E-7 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I25_02925 ffe2252e08a26a29194bbf7fd63194e6 330 SUPERFAMILY SSF50331 250 318 1.28E-6 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I25_02925 ffe2252e08a26a29194bbf7fd63194e6 330 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_02925 ffe2252e08a26a29194bbf7fd63194e6 330 Pfam PF00005 ABC transporter 18 165 2.9E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_02925 ffe2252e08a26a29194bbf7fd63194e6 330 SMART SM00382 27 215 1.2E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_02925 ffe2252e08a26a29194bbf7fd63194e6 330 SUPERFAMILY SSF52540 3 244 1.93E-82 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02925 ffe2252e08a26a29194bbf7fd63194e6 330 Gene3D G3DSA:3.40.50.300 3 280 2.2E-70 T 14-10-2018 C2I25_04010 95036ececba48396a26fd6e30c2506c9 193 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 179 6.0E-94 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I25_04010 95036ececba48396a26fd6e30c2506c9 193 Gene3D G3DSA:1.20.1200.10 12 193 8.3E-73 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I25_04010 95036ececba48396a26fd6e30c2506c9 193 Pfam PF01923 Cobalamin adenosyltransferase 4 166 1.7E-57 T 14-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I25_04010 95036ececba48396a26fd6e30c2506c9 193 SUPERFAMILY SSF89028 1 178 1.63E-64 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I25_04010 95036ececba48396a26fd6e30c2506c9 193 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 177 2.3E-63 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I25_07905 bedd935f1398ab8e0babbad1184d3676 297 SUPERFAMILY SSF161098 30 288 1.96E-36 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07905 bedd935f1398ab8e0babbad1184d3676 297 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 15 294 8.5E-86 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 C2I25_07905 bedd935f1398ab8e0babbad1184d3676 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 294 9.9E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_07905 bedd935f1398ab8e0babbad1184d3676 297 Gene3D G3DSA:1.10.3720.10 70 296 3.8E-34 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_00345 36c96e380dc15f32d39089b730f3e4cf 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 230 5.3E-72 T 14-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 C2I25_00345 36c96e380dc15f32d39089b730f3e4cf 230 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_00345 36c96e380dc15f32d39089b730f3e4cf 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 223 3.6E-59 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_00345 36c96e380dc15f32d39089b730f3e4cf 230 Gene3D G3DSA:3.40.50.1860 104 214 1.2E-84 T 14-10-2018 C2I25_00345 36c96e380dc15f32d39089b730f3e4cf 230 Gene3D G3DSA:3.40.50.1860 4 221 1.2E-84 T 14-10-2018 C2I25_00345 36c96e380dc15f32d39089b730f3e4cf 230 SUPERFAMILY SSF53681 104 214 1.16E-33 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_00345 36c96e380dc15f32d39089b730f3e4cf 230 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 192 202 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_00345 36c96e380dc15f32d39089b730f3e4cf 230 SUPERFAMILY SSF53681 1 114 5.89E-37 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I25_03530 07fcd97becd12445d5ae0b983a810c1b 84 Pfam PF13082 Protein of unknown function (DUF3931) 1 66 4.8E-50 T 14-10-2018 IPR025078 Protein of unknown function DUF3931 C2I25_03230 f61f61ff2c7ccfe3c8c2a407e51f32ce 277 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 14-10-2018 IPR000540 Flagellar motor protein MotA, conserved site C2I25_03230 f61f61ff2c7ccfe3c8c2a407e51f32ce 277 Pfam PF01618 MotA/TolQ/ExbB proton channel family 121 237 8.0E-23 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel C2I25_18680 a23e6bd66cf7e3295d8d099b435e85a8 181 SUPERFAMILY SSF55729 1 179 1.06E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_18680 a23e6bd66cf7e3295d8d099b435e85a8 181 Pfam PF13302 Acetyltransferase (GNAT) domain 9 155 2.1E-18 T 14-10-2018 IPR000182 GNAT domain C2I25_18680 a23e6bd66cf7e3295d8d099b435e85a8 181 Gene3D G3DSA:3.40.630.30 3 181 1.5E-41 T 14-10-2018 C2I25_21675 c8631c80b14bf09be4f43c4a863d1d8e 1120 SUPERFAMILY SSF52490 5 166 2.62E-7 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 C2I25_21675 c8631c80b14bf09be4f43c4a863d1d8e 1120 Gene3D G3DSA:3.40.50.1440 8 218 4.1E-11 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 C2I25_21675 c8631c80b14bf09be4f43c4a863d1d8e 1120 Pfam PF13809 Tubulin like 8 345 5.1E-74 T 14-10-2018 IPR025904 Tubulin-like C2I25_11955 c5c12c891b1ac35c4f7e604d60536389 356 Pfam PF02898 Nitric oxide synthase, oxygenase domain 4 355 3.8E-164 T 14-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 C2I25_11955 c5c12c891b1ac35c4f7e604d60536389 356 Gene3D G3DSA:3.90.1230.10 193 298 8.3E-148 T 14-10-2018 C2I25_11955 c5c12c891b1ac35c4f7e604d60536389 356 PIRSF PIRSF037219 1 356 4.5E-190 T 14-10-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.14.47|KEGG: 00330+1.14.14.47 C2I25_11955 c5c12c891b1ac35c4f7e604d60536389 356 Gene3D G3DSA:3.90.440.10 82 192 8.3E-148 T 14-10-2018 C2I25_11955 c5c12c891b1ac35c4f7e604d60536389 356 SUPERFAMILY SSF56512 3 355 5.89E-167 T 14-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 C2I25_11955 c5c12c891b1ac35c4f7e604d60536389 356 Gene3D G3DSA:3.90.340.10 6 353 8.3E-148 T 14-10-2018 C2I25_11955 c5c12c891b1ac35c4f7e604d60536389 356 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 65 72 - T 14-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 C2I25_26860 f7a2a859532cb9d82d9e09dbcdb0ca85 233 Gene3D G3DSA:3.40.50.150 17 233 1.4E-22 T 14-10-2018 C2I25_26860 f7a2a859532cb9d82d9e09dbcdb0ca85 233 SUPERFAMILY SSF53335 21 215 7.04E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_26860 f7a2a859532cb9d82d9e09dbcdb0ca85 233 Pfam PF13649 Methyltransferase domain 53 154 3.8E-13 T 14-10-2018 C2I25_11415 671fe8ae2730b0e5a79783c56f649148 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 1.2E-100 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 C2I25_11415 671fe8ae2730b0e5a79783c56f649148 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 C2I25_11415 671fe8ae2730b0e5a79783c56f649148 255 Pfam PF01026 TatD related DNase 3 252 2.0E-87 T 14-10-2018 IPR001130 TatD family GO:0016788 C2I25_11415 671fe8ae2730b0e5a79783c56f649148 255 Gene3D G3DSA:3.20.20.140 1 255 1.3E-112 T 14-10-2018 C2I25_11415 671fe8ae2730b0e5a79783c56f649148 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 C2I25_11415 671fe8ae2730b0e5a79783c56f649148 255 SUPERFAMILY SSF51556 1 254 1.25E-97 T 14-10-2018 IPR032466 Metal-dependent hydrolase C2I25_11415 671fe8ae2730b0e5a79783c56f649148 255 PIRSF PIRSF005902 1 255 2.9E-90 T 14-10-2018 IPR001130 TatD family GO:0016788 C2I25_17055 65e6247d9676c5236b8a8603944bdd40 102 SUPERFAMILY SSF141091 1 101 9.94E-39 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17055 65e6247d9676c5236b8a8603944bdd40 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 7.4E-40 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17055 65e6247d9676c5236b8a8603944bdd40 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.6E-40 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17055 65e6247d9676c5236b8a8603944bdd40 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.476 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17055 65e6247d9676c5236b8a8603944bdd40 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 14-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_25325 0ca2720129163de4adaa6c0cb7eb6105 118 Pfam PF04977 Septum formation initiator 41 117 1.6E-16 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC C2I25_07480 17bc0519f65193b10cc3a3cb34c7a687 194 Pfam PF11579 Protein of unknown function (DUF3238) 1 192 1.3E-109 T 14-10-2018 IPR021631 Protein of unknown function DUF3238 C2I25_00825 b71fe3e8ebe37ca5aedbeb0cd07b14b7 95 Pfam PF13799 Domain of unknown function (DUF4183) 23 92 4.2E-19 T 14-10-2018 IPR025237 Domain of unknown function DUF4183 C2I25_12570 b93254b36f362fecc82627403627513c 165 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 16 139 7.1E-54 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I25_12570 b93254b36f362fecc82627403627513c 165 Gene3D G3DSA:2.70.70.10 7 164 3.2E-60 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_12570 b93254b36f362fecc82627403627513c 165 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 79 91 - T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I25_12570 b93254b36f362fecc82627403627513c 165 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 17 137 2.2E-48 T 14-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I25_12570 b93254b36f362fecc82627403627513c 165 SUPERFAMILY SSF51261 8 153 3.66E-57 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_12760 4ccf48f127c7b01c01470e3cfd52e083 280 Gene3D G3DSA:3.40.50.300 2 241 2.0E-65 T 14-10-2018 C2I25_12760 4ccf48f127c7b01c01470e3cfd52e083 280 SMART SM00382 29 216 2.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_12760 4ccf48f127c7b01c01470e3cfd52e083 280 Pfam PF00005 ABC transporter 20 160 2.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_12760 4ccf48f127c7b01c01470e3cfd52e083 280 SUPERFAMILY SSF52540 4 226 1.64E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12760 4ccf48f127c7b01c01470e3cfd52e083 280 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_23555 3e4df9fa22be805fc8fa22c001c243c9 193 SUPERFAMILY SSF52540 2 185 6.66E-14 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_23555 3e4df9fa22be805fc8fa22c001c243c9 193 Pfam PF13671 AAA domain 5 125 6.3E-10 T 14-10-2018 C2I25_23555 3e4df9fa22be805fc8fa22c001c243c9 193 Gene3D G3DSA:3.40.50.300 3 188 5.0E-13 T 14-10-2018 C2I25_06890 568af6a6abc541a42e895de578e66855 76 ProDom PD049467 YFLJ 29 66 1.0E-15 T 14-10-2018 IPR022580 Protein of unknown function DUF2639 C2I25_06890 568af6a6abc541a42e895de578e66855 76 Pfam PF11121 Protein of unknown function (DUF2639) 30 66 2.4E-20 T 14-10-2018 IPR022580 Protein of unknown function DUF2639 C2I25_00185 a69ba7842dfc243d3feda2a4f7a8f4a8 320 Gene3D G3DSA:3.40.50.1980 39 144 1.2E-32 T 14-10-2018 C2I25_00185 a69ba7842dfc243d3feda2a4f7a8f4a8 320 Pfam PF01497 Periplasmic binding protein 58 294 7.4E-31 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_00185 a69ba7842dfc243d3feda2a4f7a8f4a8 320 SUPERFAMILY SSF53807 41 314 2.7E-66 T 14-10-2018 C2I25_00185 a69ba7842dfc243d3feda2a4f7a8f4a8 320 Gene3D G3DSA:3.40.50.1980 145 320 4.2E-66 T 14-10-2018 C2I25_07900 36dd9de2fb63e1c0065eb1127748938a 306 Gene3D G3DSA:1.10.3720.10 56 291 1.5E-31 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07900 36dd9de2fb63e1c0065eb1127748938a 306 SUPERFAMILY SSF161098 16 275 7.61E-40 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07900 36dd9de2fb63e1c0065eb1127748938a 306 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 285 3.7E-81 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 C2I25_07900 36dd9de2fb63e1c0065eb1127748938a 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 291 1.6E-36 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_23230 f94a571b4765f4e36a1db01bf96a302e 158 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 156 1.2E-61 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC C2I25_23230 f94a571b4765f4e36a1db01bf96a302e 158 Gene3D G3DSA:3.90.960.10 1 158 6.5E-49 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I25_23230 f94a571b4765f4e36a1db01bf96a302e 158 Pfam PF04073 Aminoacyl-tRNA editing domain 36 147 1.3E-19 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 C2I25_23230 f94a571b4765f4e36a1db01bf96a302e 158 SUPERFAMILY SSF55826 6 156 4.84E-37 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I25_23230 f94a571b4765f4e36a1db01bf96a302e 158 PIRSF PIRSF006181 1 158 7.7E-61 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC C2I25_15260 ced5e671e7e8eb4581756794c7fc240d 76 Pfam PF13129 Protein of unknown function (DUF3953) 33 69 3.1E-9 T 14-10-2018 IPR025018 Protein of unknown function DUF3953 C2I25_23970 0b414128db6c89122cda3ff37853e8e6 236 SUPERFAMILY SSF53474 54 206 1.74E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_23970 0b414128db6c89122cda3ff37853e8e6 236 Gene3D G3DSA:3.40.50.1820 43 208 2.2E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_23970 0b414128db6c89122cda3ff37853e8e6 236 Pfam PF12695 Alpha/beta hydrolase family 60 222 4.6E-67 T 14-10-2018 IPR029059 Alpha/beta hydrolase fold-5 C2I25_09300 812e9e5833ce28e859f3c0aa7d62a19d 196 Gene3D G3DSA:2.60.60.30 22 190 1.8E-70 T 14-10-2018 C2I25_09300 812e9e5833ce28e859f3c0aa7d62a19d 196 Pfam PF02342 TerD domain 5 191 1.3E-82 T 14-10-2018 IPR003325 TerD domain C2I25_17450 d24a6f977716e9d4971d264619db7505 131 SUPERFAMILY SSF48403 17 113 4.66E-8 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I25_17450 d24a6f977716e9d4971d264619db7505 131 Gene3D G3DSA:1.25.40.20 15 128 5.3E-9 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I25_27460 b8b8213cac6e20a16920f2342f3abc68 292 Gene3D G3DSA:1.25.40.10 1 292 2.9E-81 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_27460 b8b8213cac6e20a16920f2342f3abc68 292 SUPERFAMILY SSF48452 111 254 2.53E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_27460 b8b8213cac6e20a16920f2342f3abc68 292 Pfam PF12844 Helix-turn-helix domain 7 67 8.9E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_27460 b8b8213cac6e20a16920f2342f3abc68 292 SMART SM00530 9 63 8.5E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_27460 b8b8213cac6e20a16920f2342f3abc68 292 SUPERFAMILY SSF47413 5 65 2.28E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_19625 a1a826a08741bcaaaa1f8849db5130ef 48 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 22 45 2.4E-13 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_19625 a1a826a08741bcaaaa1f8849db5130ef 48 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 26 47 2.3E-12 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_05355 3a4923a7fb6de6f1c77a0b227ee1366e 281 SUPERFAMILY SSF53335 82 257 5.82E-9 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_05355 3a4923a7fb6de6f1c77a0b227ee1366e 281 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 8 280 3.5E-113 T 14-10-2018 IPR008884 Macrocin-O-methyltransferase C2I25_04135 7b5eb7bf0670435fee5b6f5fe7700ff7 206 Gene3D G3DSA:1.20.58.220 10 206 4.7E-57 T 14-10-2018 IPR038078 PhoU-like domain superfamily C2I25_04135 7b5eb7bf0670435fee5b6f5fe7700ff7 206 SUPERFAMILY SSF109755 7 197 3.84E-6 T 14-10-2018 C2I25_04135 7b5eb7bf0670435fee5b6f5fe7700ff7 206 Pfam PF01865 Protein of unknown function DUF47 5 203 3.5E-27 T 14-10-2018 IPR018445 Putative phosphate transport regulator C2I25_05730 eb0c5a9c7aa4913191be891029f5088f 193 Pfam PF06338 ComK protein 10 159 1.3E-56 T 14-10-2018 IPR010461 Competence protein ComK GO:0030420 C2I25_05730 eb0c5a9c7aa4913191be891029f5088f 193 PIRSF PIRSF011560 4 192 1.7E-71 T 14-10-2018 IPR010461 Competence protein ComK GO:0030420 C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 PIRSF PIRSF002937 11 276 1.6E-132 T 14-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 Gene3D G3DSA:3.40.50.2300 5 144 1.0E-32 T 14-10-2018 C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 165 275 2.0E-59 T 14-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 166 269 1.3E-45 T 14-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 Gene3D G3DSA:1.10.10.10 157 276 2.5E-55 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 SMART SM00448 16 131 2.1E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 14 276 1.4E-137 T 14-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 SUPERFAMILY SSF52172 14 139 3.98E-32 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 Pfam PF00072 Response regulator receiver domain 18 131 3.9E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_18465 779af38a8b7829d4ccd5367cbffe55a9 276 SUPERFAMILY SSF46894 160 274 1.19E-48 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_10925 8495325af0f263651361c510d44e0665 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_10925 8495325af0f263651361c510d44e0665 87 SUPERFAMILY SSF50249 7 84 5.57E-32 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_10925 8495325af0f263651361c510d44e0665 87 Gene3D G3DSA:2.40.50.140 6 86 1.2E-35 T 14-10-2018 C2I25_10925 8495325af0f263651361c510d44e0665 87 Pfam PF00366 Ribosomal protein S17 12 79 2.0E-32 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10925 8495325af0f263651361c510d44e0665 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 24.115 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10925 8495325af0f263651361c510d44e0665 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.5E-35 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10925 8495325af0f263651361c510d44e0665 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 1.0E-35 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10925 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.0E-11 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10925 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.0E-11 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10925 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.0E-11 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_19535 3d3c588cacdf7218ca903401744af0c4 405 SMART SM00052 3 241 1.4E-12 T 14-10-2018 IPR001633 EAL domain C2I25_19535 3d3c588cacdf7218ca903401744af0c4 405 Pfam PF00563 EAL domain 12 233 2.0E-29 T 14-10-2018 IPR001633 EAL domain C2I25_19535 3d3c588cacdf7218ca903401744af0c4 405 SUPERFAMILY SSF141868 4 256 9.68E-42 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_19535 3d3c588cacdf7218ca903401744af0c4 405 SUPERFAMILY SSF103190 263 400 3.92E-43 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I25_19535 3d3c588cacdf7218ca903401744af0c4 405 Gene3D G3DSA:3.20.20.450 1 229 1.6E-59 T 14-10-2018 IPR035919 EAL domain superfamily C2I25_19535 3d3c588cacdf7218ca903401744af0c4 405 Pfam PF10388 EAL-domain associated signalling protein domain 240 404 1.2E-79 T 14-10-2018 IPR018842 YkuI, C-terminal C2I25_19535 3d3c588cacdf7218ca903401744af0c4 405 Gene3D G3DSA:3.30.450.20 291 405 4.6E-43 T 14-10-2018 C2I25_19535 3d3c588cacdf7218ca903401744af0c4 405 Gene3D G3DSA:1.20.5.170 246 290 5.8E-13 T 14-10-2018 C2I25_14440 93f20a6fb71147708aad71186bbc7211 79 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 2 78 4.0E-38 T 14-10-2018 C2I25_14440 93f20a6fb71147708aad71186bbc7211 79 Hamap MF_01542 UPF0349 protein . 2 78 29.928 T 14-10-2018 IPR022916 Protein of unknown function UPF0349 C2I25_14440 93f20a6fb71147708aad71186bbc7211 79 Pfam PF07293 Protein of unknown function (DUF1450) 2 76 9.0E-35 T 14-10-2018 IPR009910 Protein of unknown function DUF1450 C2I25_19635 985e5084bd96e5d8db7791cce93851d1 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.1E-39 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_19635 985e5084bd96e5d8db7791cce93851d1 325 Gene3D G3DSA:3.40.50.920 193 325 5.3E-49 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_19635 985e5084bd96e5d8db7791cce93851d1 325 Gene3D G3DSA:3.40.50.970 1 192 1.1E-80 T 14-10-2018 C2I25_19635 985e5084bd96e5d8db7791cce93851d1 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 5.0E-40 T 14-10-2018 IPR033248 Transketolase, C-terminal domain C2I25_19635 985e5084bd96e5d8db7791cce93851d1 325 SUPERFAMILY SSF52922 188 325 4.32E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I25_19635 985e5084bd96e5d8db7791cce93851d1 325 SUPERFAMILY SSF52518 3 192 2.65E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_19635 985e5084bd96e5d8db7791cce93851d1 325 SMART SM00861 4 179 6.6E-65 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I25_12090 cbbcb47e3deec91b50da7c38a5ae0e4a 691 Pfam PF02554 Carbon starvation protein CstA 32 409 4.9E-172 T 14-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 C2I25_12090 cbbcb47e3deec91b50da7c38a5ae0e4a 691 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 7.0E-36 T 14-10-2018 IPR025299 CstA, C-terminal domain C2I25_23400 89a0f92ed933589972cb6deaae6e03a2 235 Pfam PF08713 DNA alkylation repair enzyme 6 215 1.3E-22 T 14-10-2018 IPR014825 DNA alkylation repair enzyme C2I25_23400 89a0f92ed933589972cb6deaae6e03a2 235 SUPERFAMILY SSF48371 1 235 3.45E-68 T 14-10-2018 IPR016024 Armadillo-type fold C2I25_11005 65c80c55c3de5ebd444ec0d23952daad 82 SUPERFAMILY SSF55315 4 81 1.38E-16 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_11005 65c80c55c3de5ebd444ec0d23952daad 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4 81 5.6E-12 T 14-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 C2I25_11005 65c80c55c3de5ebd444ec0d23952daad 82 Gene3D G3DSA:3.30.1330.30 1 81 3.5E-18 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like C2I25_13765 1d007135a05228158c2ddd49919ce782 212 SUPERFAMILY SSF51735 1 209 1.22E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_13765 1d007135a05228158c2ddd49919ce782 212 Gene3D G3DSA:3.40.50.720 1 210 3.7E-52 T 14-10-2018 C2I25_13765 1d007135a05228158c2ddd49919ce782 212 Pfam PF13460 NAD(P)H-binding 7 198 1.1E-23 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_26055 3c9c46a1acc143f35f7a2aea8cc93dc2 259 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 254 17.436 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I25_26055 3c9c46a1acc143f35f7a2aea8cc93dc2 259 Pfam PF02673 Bacitracin resistance protein BacA 6 249 4.2E-77 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I25_13235 ba0e4e2323e1ec4f4176ff38f56be2b3 371 SUPERFAMILY SSF53756 4 369 2.28E-139 T 14-10-2018 C2I25_13235 ba0e4e2323e1ec4f4176ff38f56be2b3 371 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 365 3.5E-121 T 14-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I25_13235 ba0e4e2323e1ec4f4176ff38f56be2b3 371 Gene3D G3DSA:3.40.50.2000 7 363 1.9E-161 T 14-10-2018 C2I25_13235 ba0e4e2323e1ec4f4176ff38f56be2b3 371 Gene3D G3DSA:3.40.50.2000 192 352 1.9E-161 T 14-10-2018 C2I25_13235 ba0e4e2323e1ec4f4176ff38f56be2b3 371 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 368 1.2E-165 T 14-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 C2I25_21490 ff1dab59f951a822db7a838eac050471 544 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_21490 ff1dab59f951a822db7a838eac050471 544 SUPERFAMILY SSF52540 325 542 3.4E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21490 ff1dab59f951a822db7a838eac050471 544 Gene3D G3DSA:3.40.50.300 316 544 4.0E-61 T 14-10-2018 C2I25_21490 ff1dab59f951a822db7a838eac050471 544 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 357 370 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I25_21490 ff1dab59f951a822db7a838eac050471 544 Pfam PF00005 ABC transporter 345 482 2.8E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21490 ff1dab59f951a822db7a838eac050471 544 SUPERFAMILY SSF90123 1 313 2.22E-51 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_21490 ff1dab59f951a822db7a838eac050471 544 SMART SM00382 353 528 5.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_21490 ff1dab59f951a822db7a838eac050471 544 Pfam PF00664 ABC transporter transmembrane region 20 288 6.5E-24 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_21490 ff1dab59f951a822db7a838eac050471 544 Gene3D G3DSA:1.20.1560.10 1 315 6.1E-47 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_03615 830f891f30bbb2260462c0f5c4a1a589 63 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 57 3.0E-6 T 14-10-2018 C2I25_03615 830f891f30bbb2260462c0f5c4a1a589 63 Pfam PF14178 YppF-like protein 1 58 3.6E-29 T 14-10-2018 IPR025553 YppF-like protein C2I25_25905 e832a128298ced98ea07ab9575c3368c 170 Pfam PF06445 GyrI-like small molecule binding domain 1 156 3.6E-34 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain C2I25_25905 e832a128298ced98ea07ab9575c3368c 170 SUPERFAMILY SSF55136 1 156 3.49E-30 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_25905 e832a128298ced98ea07ab9575c3368c 170 Gene3D G3DSA:3.20.80.10 1 159 9.4E-38 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I25_25905 e832a128298ced98ea07ab9575c3368c 170 SMART SM00871 1 156 1.8E-32 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I25_06350 475e6eab12a39d57e0dce53f2a3325d4 413 Gene3D G3DSA:3.60.21.10 2 254 9.7E-62 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_06350 475e6eab12a39d57e0dce53f2a3325d4 413 Pfam PF00149 Calcineurin-like phosphoesterase 5 203 7.6E-17 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_06350 475e6eab12a39d57e0dce53f2a3325d4 413 PIRSF PIRSF033091 1 413 3.2E-160 T 14-10-2018 IPR014576 Predicted phosphoesterase, YhaO type C2I25_06350 475e6eab12a39d57e0dce53f2a3325d4 413 SUPERFAMILY SSF56300 5 300 1.46E-58 T 14-10-2018 C2I25_12850 6b4c17d973a0cb0294041a769c1856b6 480 Pfam PF14296 O-antigen polysaccharide polymerase Wzy 6 471 1.3E-136 T 14-10-2018 IPR029468 O-antigen polysaccharide polymerase Wzy C2I25_12850 6b4c17d973a0cb0294041a769c1856b6 480 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 51 456 8.3E-26 T 14-10-2018 C2I25_00230 a0f4deaa0cce0da39eb0e7e6786d03ba 90 Pfam PF10751 Protein of unknown function (DUF2535) 9 90 3.0E-26 T 14-10-2018 IPR019687 Protein of unknown function DUF2535 C2I25_02390 83f2ea343b7d64d8b56aa6e163fe3775 367 SUPERFAMILY SSF56300 56 338 7.27E-45 T 14-10-2018 C2I25_02390 83f2ea343b7d64d8b56aa6e163fe3775 367 Gene3D G3DSA:3.60.21.10 110 350 1.6E-13 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_02390 83f2ea343b7d64d8b56aa6e163fe3775 367 SMART SM00854 57 297 1.4E-84 T 14-10-2018 IPR019079 Capsule synthesis protein, CapA C2I25_02390 83f2ea343b7d64d8b56aa6e163fe3775 367 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 57 296 2.5E-70 T 14-10-2018 IPR019079 Capsule synthesis protein, CapA C2I25_05180 27b8a5d3576fcef589151d460346bd9e 227 Pfam PF10042 Uncharacterized conserved protein (DUF2278) 1 212 5.1E-74 T 14-10-2018 IPR019268 Protein of unknown function DUF2278 C2I25_09835 f90025699b38807d092da85154a72a4e 256 Pfam PF01925 Sulfite exporter TauE/SafE 12 245 8.1E-43 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I25_05590 f76cfe62985dc2211a4aaa983e2a21c8 43 Pfam PF13081 Domain of unknown function (DUF3941) 18 41 1.1E-14 T 14-10-2018 IPR025077 Protein of unknown function DUF3941 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 SMART SM00421 146 203 2.1E-29 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 9.5E-23 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 SUPERFAMILY SSF52172 1 134 3.56E-32 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.1E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.1E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.1E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 SUPERFAMILY SSF46894 138 208 9.52E-25 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 Pfam PF00072 Response regulator receiver domain 4 115 1.2E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 SMART SM00448 2 115 1.7E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_04210 91a0c5e1459ad641ecb13ad6329bb4d5 210 Gene3D G3DSA:3.40.50.12740 2 209 5.6E-76 T 14-10-2018 C2I25_02780 70f6369435ff847492728840f83f1ee5 467 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 5 457 4.7E-200 T 14-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 C2I25_02780 70f6369435ff847492728840f83f1ee5 467 Pfam PF03553 Na+/H+ antiporter family 159 451 5.5E-67 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I25_05005 90025efe95b5ff0da4798d35fabd33cd 44 Pfam PF08671 Anti-repressor SinI 9 36 4.2E-12 T 14-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 C2I25_05005 90025efe95b5ff0da4798d35fabd33cd 44 SUPERFAMILY SSF47406 8 35 2.62E-7 T 14-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I25_01295 5f9cba6319a5641d364f2be0eeaaed5f 405 Gene3D G3DSA:1.20.1250.20 10 392 1.0E-22 T 14-10-2018 C2I25_01295 5f9cba6319a5641d364f2be0eeaaed5f 405 Pfam PF07690 Major Facilitator Superfamily 37 345 3.7E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_01295 5f9cba6319a5641d364f2be0eeaaed5f 405 SUPERFAMILY SSF103473 15 398 1.31E-30 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_09540 8ba778cea1912640a0603dd94e1e3384 369 SUPERFAMILY SSF52540 28 176 6.55E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09540 8ba778cea1912640a0603dd94e1e3384 369 Gene3D G3DSA:3.40.50.300 8 185 2.3E-6 T 14-10-2018 C2I25_09540 8ba778cea1912640a0603dd94e1e3384 369 Gene3D G3DSA:3.40.50.300 214 250 2.9E-5 T 14-10-2018 C2I25_09540 8ba778cea1912640a0603dd94e1e3384 369 SUPERFAMILY SSF52540 210 292 8.01E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_12610 00462bfb21b4e91f591870d088fd8ea9 37 Pfam PF13216 Protein of unknown function (DUF4024) 1 35 1.5E-28 T 14-10-2018 IPR025099 Protein of unknown function DUF4024 C2I25_04895 4ac80fe0349e364195b3bfaa7c9549d7 236 Hamap MF_02104 Lactate utilization protein C [lutC]. 4 236 48.617 T 14-10-2018 IPR022823 Lactate utilization protein C C2I25_04895 4ac80fe0349e364195b3bfaa7c9549d7 236 SUPERFAMILY SSF100950 46 236 8.79E-39 T 14-10-2018 IPR037171 NagB/RpiA transferase-like C2I25_04895 4ac80fe0349e364195b3bfaa7c9549d7 236 Pfam PF02589 LUD domain 51 236 6.5E-34 T 14-10-2018 IPR003741 LUD domain C2I25_04895 4ac80fe0349e364195b3bfaa7c9549d7 236 Gene3D G3DSA:3.40.50.10420 44 236 1.3E-36 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily C2I25_13810 28f980776023b242b42cf6d4cce7e09d 167 Gene3D G3DSA:1.20.120.450 2 163 1.5E-40 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_13810 28f980776023b242b42cf6d4cce7e09d 167 Pfam PF05163 DinB family 1 166 9.7E-36 T 14-10-2018 IPR007837 DNA damage-inducible protein DinB C2I25_13810 28f980776023b242b42cf6d4cce7e09d 167 SUPERFAMILY SSF109854 5 150 9.52E-29 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_10240 d61fdac76d27a8c422106700e14804e8 152 Hamap MF_00745 Protein SprT-like. 4 148 40.152 T 14-10-2018 IPR023524 Uncharacterised protein family SprT-like C2I25_10240 d61fdac76d27a8c422106700e14804e8 152 Pfam PF10263 SprT-like family 7 97 1.4E-12 T 14-10-2018 IPR006640 SprT-like C2I25_10240 d61fdac76d27a8c422106700e14804e8 152 SMART SM00731 4 148 1.9E-47 T 14-10-2018 IPR006640 SprT-like C2I25_14355 a296a2678ae8be9483d1020634f1db05 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 77 4.0E-29 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 C2I25_14355 a296a2678ae8be9483d1020634f1db05 78 Pfam PF01106 NifU-like domain 11 75 5.0E-28 T 14-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 C2I25_14355 a296a2678ae8be9483d1020634f1db05 78 Gene3D G3DSA:3.30.300.130 1 78 6.9E-33 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I25_14355 a296a2678ae8be9483d1020634f1db05 78 SUPERFAMILY SSF117916 2 77 2.45E-26 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I25_15510 130577c6b78a5282866150166dbd4147 87 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 6.3E-35 T 14-10-2018 IPR019668 Uncharacterised protein family YtzC C2I25_05140 aff2a60130ad0741c26e7aa84c70aea9 136 Pfam PF13048 Protein of unknown function (DUF3908) 4 126 2.8E-50 T 14-10-2018 IPR025020 Protein of unknown function DUF3908 C2I25_01545 0ebfbd23eddc4deaa07164354085b85c 151 Pfam PF13075 Protein of unknown function (DUF3939) 10 140 4.3E-45 T 14-10-2018 IPR025071 Protein of unknown function DUF3939 C2I25_09680 e82207a7af21d521f8bf9c7a2e72d1ed 172 Pfam PF07308 Protein of unknown function (DUF1456) 105 172 2.0E-21 T 14-10-2018 IPR009921 Domain of unknown function DUF1456 C2I25_09680 e82207a7af21d521f8bf9c7a2e72d1ed 172 Pfam PF07308 Protein of unknown function (DUF1456) 5 86 7.0E-27 T 14-10-2018 IPR009921 Domain of unknown function DUF1456 C2I25_12080 213eb600a727457153a1be9752a929c2 399 Gene3D G3DSA:1.20.1250.20 9 399 9.8E-93 T 14-10-2018 C2I25_12080 213eb600a727457153a1be9752a929c2 399 SUPERFAMILY SSF103473 9 397 2.49E-87 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_12080 213eb600a727457153a1be9752a929c2 399 Pfam PF07690 Major Facilitator Superfamily 21 257 4.4E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_12080 213eb600a727457153a1be9752a929c2 399 ProSitePatterns PS00217 Sugar transport proteins signature 2. 108 133 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_12080 213eb600a727457153a1be9752a929c2 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 269 284 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_12230 a92a60b2ea2ed506603eb2d665ba0d67 247 SUPERFAMILY SSF54909 1 246 1.61E-94 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_12230 a92a60b2ea2ed506603eb2d665ba0d67 247 Gene3D G3DSA:3.30.70.1100 137 247 1.3E-47 T 14-10-2018 C2I25_12230 a92a60b2ea2ed506603eb2d665ba0d67 247 Pfam PF06778 Chlorite dismutase 33 235 1.6E-76 T 14-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase C2I25_12230 a92a60b2ea2ed506603eb2d665ba0d67 247 Hamap MF_01442 Putative heme-dependent peroxidase . 1 247 57.578 T 14-10-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family C2I25_12230 a92a60b2ea2ed506603eb2d665ba0d67 247 Gene3D G3DSA:3.30.70.1030 1 136 2.7E-55 T 14-10-2018 C2I25_26395 01d72239a39db219d57e05fad8c49dec 266 Pfam PF02361 Cobalt transport protein 3 223 5.2E-29 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component C2I25_16045 15c7ef0c7e5f119f5aa4d30bc4fdb146 570 Pfam PF06160 Septation ring formation regulator, EzrA 7 561 7.6E-172 T 14-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 C2I25_16045 15c7ef0c7e5f119f5aa4d30bc4fdb146 570 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 5 566 21.826 T 14-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 C2I25_03565 929b3871cdcbfeddcf60b51c2ccfb067 157 SUPERFAMILY SSF55729 1 150 1.17E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_03565 929b3871cdcbfeddcf60b51c2ccfb067 157 Pfam PF00583 Acetyltransferase (GNAT) family 31 130 1.4E-11 T 14-10-2018 IPR000182 GNAT domain C2I25_03565 929b3871cdcbfeddcf60b51c2ccfb067 157 Gene3D G3DSA:3.40.630.30 4 152 9.3E-21 T 14-10-2018 C2I25_13840 88d533b09755ca798e6afb5192501a1b 399 Pfam PF00999 Sodium/hydrogen exchanger family 12 378 2.9E-63 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I25_13840 88d533b09755ca798e6afb5192501a1b 399 Gene3D G3DSA:1.20.1530.20 2 386 6.1E-64 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily C2I25_00325 14a1ecb5b0dc7b33403651d9ff270a15 72 Gene3D G3DSA:1.10.260.40 6 72 2.1E-10 T 14-10-2018 C2I25_00325 14a1ecb5b0dc7b33403651d9ff270a15 72 SMART SM00530 6 62 2.2E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_00325 14a1ecb5b0dc7b33403651d9ff270a15 72 SUPERFAMILY SSF47413 1 69 4.5E-19 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_00325 14a1ecb5b0dc7b33403651d9ff270a15 72 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 5.8E-24 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_05705 85b40e1957c2bb2ec16f2b566b51ae6c 92 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 39 86 9.3E-8 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_05705 85b40e1957c2bb2ec16f2b566b51ae6c 92 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 51 92 0.002 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I25_05705 85b40e1957c2bb2ec16f2b566b51ae6c 92 SUPERFAMILY SSF47789 39 92 7.59E-13 T 14-10-2018 C2I25_05705 85b40e1957c2bb2ec16f2b566b51ae6c 92 Gene3D G3DSA:1.10.150.20 36 92 1.8E-14 T 14-10-2018 C2I25_25055 49d53498bab94a0f48148e03e4d71f3f 159 Pfam PF07301 Protein of unknown function (DUF1453) 7 150 1.4E-44 T 14-10-2018 IPR009916 Protein of unknown function DUF1453 C2I25_25055 49d53498bab94a0f48148e03e4d71f3f 159 PIRSF PIRSF021441 1 159 4.6E-55 T 14-10-2018 IPR031306 CcdC protein C2I25_03450 cc13fc226a0858ce0f409e7a8db909ac 212 Pfam PF02397 Bacterial sugar transferase 27 206 3.1E-64 T 14-10-2018 IPR003362 Bacterial sugar transferase C2I25_21085 5bd8d1bc756f3de50c88f7a6891be47a 583 SUPERFAMILY SSF90123 7 318 3.14E-73 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_21085 5bd8d1bc756f3de50c88f7a6891be47a 583 Pfam PF00005 ABC transporter 353 501 1.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21085 5bd8d1bc756f3de50c88f7a6891be47a 583 Gene3D G3DSA:3.40.50.300 327 579 3.1E-81 T 14-10-2018 C2I25_21085 5bd8d1bc756f3de50c88f7a6891be47a 583 Pfam PF00664 ABC transporter transmembrane region 19 291 3.5E-50 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_21085 5bd8d1bc756f3de50c88f7a6891be47a 583 SMART SM00382 362 554 4.8E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_21085 5bd8d1bc756f3de50c88f7a6891be47a 583 SUPERFAMILY SSF52540 327 573 6.71E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21085 5bd8d1bc756f3de50c88f7a6891be47a 583 Gene3D G3DSA:1.20.1560.10 2 319 2.0E-80 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_21085 5bd8d1bc756f3de50c88f7a6891be47a 583 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_12840 6f37b2be9923092ac0b7af911c3e9370 204 Pfam PF02397 Bacterial sugar transferase 7 187 4.7E-63 T 14-10-2018 IPR003362 Bacterial sugar transferase C2I25_25580 654948a80840a595f8a9ea93a3525e69 235 Gene3D G3DSA:3.40.50.150 30 235 6.8E-47 T 14-10-2018 C2I25_25580 654948a80840a595f8a9ea93a3525e69 235 SUPERFAMILY SSF53335 1 201 2.15E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_25580 654948a80840a595f8a9ea93a3525e69 235 Pfam PF08241 Methyltransferase domain 49 141 1.4E-26 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_06140 74acad9dc98291114a903a89674b43eb 414 Pfam PF01764 Lipase (class 3) 144 186 5.0E-6 T 14-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 C2I25_06140 74acad9dc98291114a903a89674b43eb 414 Gene3D G3DSA:3.40.50.1820 5 271 1.6E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_06140 74acad9dc98291114a903a89674b43eb 414 SUPERFAMILY SSF53474 8 240 9.56E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_04425 bded37016edbddc1fb5bfb1482eab2de 298 Gene3D G3DSA:3.20.10.10 125 295 7.4E-55 T 14-10-2018 C2I25_04425 bded37016edbddc1fb5bfb1482eab2de 298 SUPERFAMILY SSF56752 4 291 5.23E-94 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 C2I25_04425 bded37016edbddc1fb5bfb1482eab2de 298 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 7 289 2.6E-103 T 14-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 C2I25_04425 bded37016edbddc1fb5bfb1482eab2de 298 Gene3D G3DSA:3.30.470.10 1 124 2.5E-47 T 14-10-2018 C2I25_04425 bded37016edbddc1fb5bfb1482eab2de 298 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 C2I25_04425 bded37016edbddc1fb5bfb1482eab2de 298 Pfam PF01063 Amino-transferase class IV 32 258 5.7E-60 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 C2I25_21255 9ed968245e19a4803cfb891d7dac00d2 522 PIRSF PIRSF006429 1 522 3.6E-148 T 14-10-2018 IPR024188 Glutamate synthase large subunit-like protein C2I25_21255 9ed968245e19a4803cfb891d7dac00d2 522 SUPERFAMILY SSF51395 7 518 3.3E-90 T 14-10-2018 C2I25_21255 9ed968245e19a4803cfb891d7dac00d2 522 Gene3D G3DSA:3.20.20.70 122 519 3.1E-84 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_21255 9ed968245e19a4803cfb891d7dac00d2 522 Pfam PF01645 Conserved region in glutamate synthase 139 491 5.8E-78 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 C2I25_14485 1234ff07fbaa81d51ada855d87231684 153 Pfam PF04463 Protein of unknown function (DUF523) 2 146 2.4E-43 T 14-10-2018 IPR007553 Domain of unknown function DUF523 C2I25_22930 11b317a794fc03903fdbf58cd183f59b 441 PIRSF PIRSF002746 1 441 6.5E-145 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_22930 11b317a794fc03903fdbf58cd183f59b 441 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 5 441 1.2E-137 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_22930 11b317a794fc03903fdbf58cd183f59b 441 Pfam PF02447 GntP family permease 5 439 1.7E-145 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_16910 65de769a0863353a8a141867a8ffa8a9 332 Gene3D G3DSA:1.25.40.10 9 264 9.0E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_16910 65de769a0863353a8a141867a8ffa8a9 332 SUPERFAMILY SSF48452 15 212 1.03E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_13855 df193cd73eeeae72c45130d6167e0f97 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.3E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_13855 df193cd73eeeae72c45130d6167e0f97 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.3E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_13855 df193cd73eeeae72c45130d6167e0f97 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.3E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_13855 df193cd73eeeae72c45130d6167e0f97 136 Pfam PF01047 MarR family 36 85 2.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_13855 df193cd73eeeae72c45130d6167e0f97 136 SUPERFAMILY SSF46785 5 135 7.76E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_13855 df193cd73eeeae72c45130d6167e0f97 136 SMART SM00347 28 125 6.9E-22 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_13855 df193cd73eeeae72c45130d6167e0f97 136 Gene3D G3DSA:1.10.10.10 1 136 2.6E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 Gene3D G3DSA:2.60.120.260 405 577 3.7E-43 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 71 350 3.4E-74 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 91 107 3.4E-6 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 57 67 3.4E-6 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 75 84 3.4E-6 T 14-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 Gene3D G3DSA:3.40.50.1820 287 393 1.7E-6 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 374 573 3.6E-30 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 SUPERFAMILY SSF49785 432 578 2.1E-38 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 SMART SM00939 362 576 9.0E-42 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 Gene3D G3DSA:3.40.50.1820 56 272 1.7E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_25285 44117eb2a7b9ea2acfec3eaf05f4ddf5 579 SUPERFAMILY SSF53474 37 392 7.04E-82 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 42.792 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 Gene3D G3DSA:3.90.226.10 1 193 4.5E-78 T 14-10-2018 C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 SUPERFAMILY SSF52096 11 191 3.23E-69 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 2.0E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 2.0E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 2.0E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 2.0E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 2.0E-50 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 Pfam PF00574 Clp protease 14 192 1.2E-83 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 14-10-2018 IPR033135 ClpP, histidine active site C2I25_25630 cc96ad05dd80b5b7b4c2ea6f6b0554e1 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 1.6E-99 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I25_23930 abb7a37e992a8ad8365be05f685c58bd 280 Pfam PF01522 Polysaccharide deacetylase 74 184 4.0E-26 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_23930 abb7a37e992a8ad8365be05f685c58bd 280 SUPERFAMILY SSF88713 75 267 4.7E-52 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_23930 abb7a37e992a8ad8365be05f685c58bd 280 Gene3D G3DSA:3.20.20.370 36 269 5.4E-57 T 14-10-2018 C2I25_11255 8281ea94f890a30087058207b4bb7cfa 465 Pfam PF04715 Anthranilate synthase component I, N terminal region 24 148 5.4E-33 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_11255 8281ea94f890a30087058207b4bb7cfa 465 PRINTS PR00095 Anthranilate synthase component I signature 406 420 2.9E-19 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_11255 8281ea94f890a30087058207b4bb7cfa 465 PRINTS PR00095 Anthranilate synthase component I signature 311 324 2.9E-19 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_11255 8281ea94f890a30087058207b4bb7cfa 465 PRINTS PR00095 Anthranilate synthase component I signature 391 405 2.9E-19 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_11255 8281ea94f890a30087058207b4bb7cfa 465 PRINTS PR00095 Anthranilate synthase component I signature 297 310 2.9E-19 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_11255 8281ea94f890a30087058207b4bb7cfa 465 Gene3D G3DSA:3.60.120.10 10 464 1.0E-167 T 14-10-2018 IPR005801 ADC synthase GO:0009058 C2I25_11255 8281ea94f890a30087058207b4bb7cfa 465 SUPERFAMILY SSF56322 9 456 5.63E-150 T 14-10-2018 IPR005801 ADC synthase GO:0009058 C2I25_11255 8281ea94f890a30087058207b4bb7cfa 465 Pfam PF00425 chorismate binding enzyme 197 449 3.4E-100 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal C2I25_00960 b1ea3d3d16f59bf93001b87e4c7ac479 235 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 11 231 9.7E-86 T 14-10-2018 IPR019903 Repair of iron centres family C2I25_00960 b1ea3d3d16f59bf93001b87e4c7ac479 235 Pfam PF01814 Hemerythrin HHE cation binding domain 84 231 6.1E-26 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 C2I25_00960 b1ea3d3d16f59bf93001b87e4c7ac479 235 Pfam PF04405 Domain of Unknown function (DUF542) 9 61 2.7E-21 T 14-10-2018 IPR019903 Repair of iron centres family C2I25_00960 b1ea3d3d16f59bf93001b87e4c7ac479 235 Gene3D G3DSA:1.20.120.520 69 235 4.4E-20 T 14-10-2018 C2I25_19630 e0e3385e4bfbe220de26761c939ec53f 371 Gene3D G3DSA:3.40.50.970 5 371 2.4E-122 T 14-10-2018 C2I25_19630 e0e3385e4bfbe220de26761c939ec53f 371 SUPERFAMILY SSF52518 18 366 3.34E-101 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I25_19630 e0e3385e4bfbe220de26761c939ec53f 371 Pfam PF00676 Dehydrogenase E1 component 53 343 1.1E-102 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 C2I25_19630 e0e3385e4bfbe220de26761c939ec53f 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 25 364 1.6E-141 T 14-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 C2I25_13050 8b971b4543c78bf7f604893b18ab168d 642 PIRSF PIRSF005091 1 623 9.6E-175 T 14-10-2018 IPR012160 Lipoteichoic acid synthase-like C2I25_13050 8b971b4543c78bf7f604893b18ab168d 642 Pfam PF00884 Sulfatase 248 538 8.6E-38 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I25_13050 8b971b4543c78bf7f604893b18ab168d 642 Gene3D G3DSA:3.40.720.10 241 548 9.2E-76 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_13050 8b971b4543c78bf7f604893b18ab168d 642 SUPERFAMILY SSF53649 246 619 1.08E-71 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_12455 844b896a8c3600561a600c6746bea107 376 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_12455 844b896a8c3600561a600c6746bea107 376 SUPERFAMILY SSF56645 1 239 2.23E-86 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I25_12455 844b896a8c3600561a600c6746bea107 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.5E-37 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I25_12455 844b896a8c3600561a600c6746bea107 376 Gene3D G3DSA:1.10.540.10 1 118 6.4E-44 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I25_12455 844b896a8c3600561a600c6746bea107 376 Gene3D G3DSA:2.40.110.10 120 233 7.1E-46 T 14-10-2018 C2I25_12455 844b896a8c3600561a600c6746bea107 376 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I25_12455 844b896a8c3600561a600c6746bea107 376 Gene3D G3DSA:1.20.140.10 234 376 5.8E-59 T 14-10-2018 C2I25_12455 844b896a8c3600561a600c6746bea107 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 8.4E-55 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I25_12455 844b896a8c3600561a600c6746bea107 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 7.0E-26 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I25_12455 844b896a8c3600561a600c6746bea107 376 PIRSF PIRSF016578 6 366 5.3E-22 T 14-10-2018 C2I25_12455 844b896a8c3600561a600c6746bea107 376 SUPERFAMILY SSF47203 226 376 4.99E-62 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I25_16835 5138d5d9eee54fe7de48fc6e173a0280 212 Gene3D G3DSA:1.10.357.10 13 179 9.1E-18 T 14-10-2018 C2I25_16835 5138d5d9eee54fe7de48fc6e173a0280 212 SUPERFAMILY SSF46689 12 66 2.89E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_16835 5138d5d9eee54fe7de48fc6e173a0280 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 56 1.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_02600 e67100a9e15030928da3026faf9334fd 310 SMART SM00448 4 114 1.7E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_02600 e67100a9e15030928da3026faf9334fd 310 SUPERFAMILY SSF52172 5 136 2.42E-22 T 14-10-2018 IPR011006 CheY-like superfamily C2I25_02600 e67100a9e15030928da3026faf9334fd 310 Gene3D G3DSA:3.40.50.2300 4 130 3.3E-21 T 14-10-2018 C2I25_02600 e67100a9e15030928da3026faf9334fd 310 Pfam PF08664 YcbB domain 161 299 9.8E-49 T 14-10-2018 IPR013972 YcbB domain C2I25_02600 e67100a9e15030928da3026faf9334fd 310 Pfam PF00072 Response regulator receiver domain 5 114 3.2E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I25_26845 a6950838cb388ec9725872bda8da3f2b 304 Gene3D G3DSA:2.60.120.580 42 208 5.5E-65 T 14-10-2018 C2I25_26845 a6950838cb388ec9725872bda8da3f2b 304 Gene3D G3DSA:2.40.10.120 84 127 5.5E-65 T 14-10-2018 C2I25_26845 a6950838cb388ec9725872bda8da3f2b 304 SUPERFAMILY SSF141130 2 290 1.83E-87 T 14-10-2018 C2I25_26845 a6950838cb388ec9725872bda8da3f2b 304 Gene3D G3DSA:3.10.28.20 214 291 1.0E-18 T 14-10-2018 C2I25_26845 a6950838cb388ec9725872bda8da3f2b 304 Pfam PF03069 Acetamidase/Formamidase family 15 141 4.7E-13 T 14-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 C2I25_26845 a6950838cb388ec9725872bda8da3f2b 304 Pfam PF03069 Acetamidase/Formamidase family 148 214 4.1E-20 T 14-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 C2I25_07935 f7e32e90af6a6abf22023dbec7c14f8c 390 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 214 382 2.3E-33 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_07935 f7e32e90af6a6abf22023dbec7c14f8c 390 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 383 1.4E-104 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_07935 f7e32e90af6a6abf22023dbec7c14f8c 390 Gene3D G3DSA:3.30.300.210 231 384 1.3E-33 T 14-10-2018 IPR038501 Spore germination GerAC superfamily C2I25_14995 e5cf4e1a119d02b59ce0c6a33c79007c 659 PIRSF PIRSF018968 1 653 5.3E-125 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_14995 e5cf4e1a119d02b59ce0c6a33c79007c 659 Pfam PF02687 FtsX-like permease family 84 169 9.4E-7 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_16100 ec9993845f480b40a8a53cd6afe7a8fe 166 SUPERFAMILY SSF52833 3 160 2.09E-43 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_16100 ec9993845f480b40a8a53cd6afe7a8fe 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 14-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 C2I25_16100 ec9993845f480b40a8a53cd6afe7a8fe 166 Pfam PF08534 Redoxin 19 159 5.3E-24 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 C2I25_16100 ec9993845f480b40a8a53cd6afe7a8fe 166 Hamap MF_00269 Thiol peroxidase [tpx]. 3 163 38.266 T 14-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 C2I25_16100 ec9993845f480b40a8a53cd6afe7a8fe 166 Gene3D G3DSA:3.40.30.10 1 165 3.3E-47 T 14-10-2018 C2I25_02110 1ff371db2c1ba3c9a1eece0862f2ffce 139 SUPERFAMILY SSF54593 3 135 9.76E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_02110 1ff371db2c1ba3c9a1eece0862f2ffce 139 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 119 4.4E-20 T 14-10-2018 C2I25_02110 1ff371db2c1ba3c9a1eece0862f2ffce 139 Gene3D G3DSA:3.10.180.10 2 134 1.1E-34 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 15 143 4.9E-28 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 179 484 3.8E-117 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 SUPERFAMILY SSF53187 175 489 3.77E-114 T 14-10-2018 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 SUPERFAMILY SSF52949 11 175 4.41E-32 T 14-10-2018 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 493 35.169 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 PRINTS PR00481 Cytosol aminopeptidase signature 314 335 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 PRINTS PR00481 Cytosol aminopeptidase signature 336 356 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 PRINTS PR00481 Cytosol aminopeptidase signature 277 298 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 PRINTS PR00481 Cytosol aminopeptidase signature 364 379 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 PRINTS PR00481 Cytosol aminopeptidase signature 255 272 1.9E-50 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 Gene3D G3DSA:3.40.630.10 165 490 2.9E-126 T 14-10-2018 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 340 347 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 C2I25_14535 d5e61db040f8762ccc477db7494afc52 494 Gene3D G3DSA:3.40.220.10 2 151 4.6E-33 T 14-10-2018 C2I25_08990 aa2ac81b981838f1c31d1bf2c092d912 326 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 180 3.2E-29 T 14-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase C2I25_03160 7923676e39f47aecf71f48a2b98d6944 122 SUPERFAMILY SSF101116 2 120 1.83E-22 T 14-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 C2I25_03160 7923676e39f47aecf71f48a2b98d6944 122 Pfam PF02561 Flagellar protein FliS 5 116 1.1E-18 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 C2I25_03160 7923676e39f47aecf71f48a2b98d6944 122 Gene3D G3DSA:1.20.120.340 1 121 1.9E-14 T 14-10-2018 C2I25_05425 884361bcad41b278a21536b5e9056fb7 608 Pfam PF01432 Peptidase family M3 211 591 9.7E-84 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 C2I25_05425 884361bcad41b278a21536b5e9056fb7 608 Pfam PF08439 Oligopeptidase F 120 189 2.4E-26 T 14-10-2018 IPR013647 Oligopeptidase F, N-terminal domain C2I25_05425 884361bcad41b278a21536b5e9056fb7 608 Gene3D G3DSA:1.10.287.830 187 233 1.7E-20 T 14-10-2018 C2I25_05425 884361bcad41b278a21536b5e9056fb7 608 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 13 602 6.2E-224 T 14-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 C2I25_05425 884361bcad41b278a21536b5e9056fb7 608 SUPERFAMILY SSF55486 10 587 5.94E-142 T 14-10-2018 C2I25_05425 884361bcad41b278a21536b5e9056fb7 608 Gene3D G3DSA:1.10.1370.20 234 607 5.4E-145 T 14-10-2018 C2I25_05425 884361bcad41b278a21536b5e9056fb7 608 Gene3D G3DSA:1.20.140.70 30 185 1.9E-59 T 14-10-2018 C2I25_00135 ab23bfda6769cde1fd20b3c4d24a8b1e 287 Pfam PF02567 Phenazine biosynthesis-like protein 9 275 4.0E-53 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I25_00135 ab23bfda6769cde1fd20b3c4d24a8b1e 287 Gene3D G3DSA:3.10.310.10 1 128 1.5E-31 T 14-10-2018 C2I25_00135 ab23bfda6769cde1fd20b3c4d24a8b1e 287 Gene3D G3DSA:3.10.310.10 131 272 2.1E-43 T 14-10-2018 C2I25_00135 ab23bfda6769cde1fd20b3c4d24a8b1e 287 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 283 2.1E-54 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I25_00135 ab23bfda6769cde1fd20b3c4d24a8b1e 287 SUPERFAMILY SSF54506 1 279 1.92E-68 T 14-10-2018 C2I25_00135 ab23bfda6769cde1fd20b3c4d24a8b1e 287 PIRSF PIRSF016184 1 283 6.8E-80 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I25_26110 f1562aad5643c9fb9fdc8155d2716dd4 271 Gene3D G3DSA:2.30.320.10 3 270 8.8E-99 T 14-10-2018 IPR035948 YwqG-like superfamily C2I25_26110 f1562aad5643c9fb9fdc8155d2716dd4 271 Pfam PF09234 Domain of unknown function (DUF1963) 42 270 1.9E-69 T 14-10-2018 IPR015315 Protein of unknown function DUF1963 C2I25_26110 f1562aad5643c9fb9fdc8155d2716dd4 271 SUPERFAMILY SSF103032 7 270 1.1E-89 T 14-10-2018 IPR035948 YwqG-like superfamily C2I25_24305 e353672778284d110f4625a75b843bf7 149 Pfam PF13302 Acetyltransferase (GNAT) domain 47 134 9.0E-21 T 14-10-2018 IPR000182 GNAT domain C2I25_24305 e353672778284d110f4625a75b843bf7 149 SUPERFAMILY SSF55729 2 136 7.02E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24305 e353672778284d110f4625a75b843bf7 149 Gene3D G3DSA:3.40.630.30 1 145 5.0E-32 T 14-10-2018 C2I25_23565 e9c1a8ebc1244343609abafba77d8403 72 SUPERFAMILY SSF103365 5 71 1.18E-13 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 C2I25_23565 e9c1a8ebc1244343609abafba77d8403 72 Pfam PF01139 tRNA-splicing ligase RtcB 38 71 4.7E-7 T 14-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 C2I25_23565 e9c1a8ebc1244343609abafba77d8403 72 Gene3D G3DSA:3.90.1860.10 4 72 2.4E-8 T 14-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 C2I25_19615 43cceb5f6cd69b2c15bb6f4e60619674 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 250 1.1E-66 T 14-10-2018 IPR000150 Cof family GO:0016787 C2I25_19615 43cceb5f6cd69b2c15bb6f4e60619674 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 6.2E-22 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I25_19615 43cceb5f6cd69b2c15bb6f4e60619674 257 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 14-10-2018 C2I25_19615 43cceb5f6cd69b2c15bb6f4e60619674 257 Gene3D G3DSA:3.40.50.1000 4 248 3.6E-86 T 14-10-2018 IPR023214 HAD superfamily C2I25_19615 43cceb5f6cd69b2c15bb6f4e60619674 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 250 2.4E-63 T 14-10-2018 C2I25_19615 43cceb5f6cd69b2c15bb6f4e60619674 257 SUPERFAMILY SSF56784 1 252 2.84E-69 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_19615 43cceb5f6cd69b2c15bb6f4e60619674 257 Gene3D G3DSA:3.30.1240.10 81 180 3.6E-86 T 14-10-2018 C2I25_03355 f48090aae0067d9a2a47d4da46702139 210 Pfam PF01810 LysE type translocator 13 204 1.1E-29 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_07985 342fa0f86711b7cf55eed8dde9265718 200 Pfam PF00510 Cytochrome c oxidase subunit III 22 197 1.5E-14 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07985 342fa0f86711b7cf55eed8dde9265718 200 SUPERFAMILY SSF81452 18 197 1.83E-53 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07985 342fa0f86711b7cf55eed8dde9265718 200 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 11 199 1.4E-104 T 14-10-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 C2I25_07985 342fa0f86711b7cf55eed8dde9265718 200 Gene3D G3DSA:1.20.120.80 14 199 1.0E-53 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_11960 a3dd75314a8fae5078e0611708be8d79 522 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 12 493 1.4E-147 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 Gene3D G3DSA:3.40.50.300 288 564 2.5E-67 T 14-10-2018 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 405 421 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 SMART SM00533 9 311 2.8E-20 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 Gene3D G3DSA:1.10.1420.10 35 277 1.3E-5 T 14-10-2018 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 Gene3D G3DSA:1.10.1420.10 113 223 1.3E-5 T 14-10-2018 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 PIRSF PIRSF005814 570 633 0.1 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 PIRSF PIRSF005814 1 582 2.5E-210 T 14-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 SUPERFAMILY SSF48334 21 284 3.53E-21 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 Pfam PF00488 MutS domain V 326 507 1.7E-31 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 SMART SM00534 323 508 3.1E-52 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I25_22295 2a90303548c05072a81401d96c6a48dc 633 SUPERFAMILY SSF52540 289 511 3.09E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24205 93babf1559fa5ed0cf84d2638daa4d53 225 Pfam PF03932 CutC family 2 199 3.7E-56 T 14-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I25_24205 93babf1559fa5ed0cf84d2638daa4d53 225 SUPERFAMILY SSF110395 1 224 1.27E-61 T 14-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I25_24205 93babf1559fa5ed0cf84d2638daa4d53 225 Gene3D G3DSA:3.20.20.380 1 225 3.7E-86 T 14-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I25_24205 93babf1559fa5ed0cf84d2638daa4d53 225 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 1 203 25.864 T 14-10-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I25_04600 5c16aaf285c88e0b0862eb20e9b4630d 137 Gene3D G3DSA:1.20.1290.10 12 137 6.5E-11 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I25_04600 5c16aaf285c88e0b0862eb20e9b4630d 137 SUPERFAMILY SSF69118 15 137 5.33E-21 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I25_26750 202ee43907fdf2b899ea13bf0d4d20ef 233 Pfam PF13111 Protein of unknown function (DUF3962) 5 216 1.2E-108 T 14-10-2018 IPR025085 Domain of unknown function DUF3962 C2I25_23920 3723b0aad8284232ce69e353d5d8798a 303 PIRSF PIRSF005355 1 302 6.3E-84 T 14-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 C2I25_23920 3723b0aad8284232ce69e353d5d8798a 303 Pfam PF01040 UbiA prenyltransferase family 27 254 1.4E-35 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 C2I25_23920 3723b0aad8284232ce69e353d5d8798a 303 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 9 297 18.745 T 14-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I25_23920 3723b0aad8284232ce69e353d5d8798a 303 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 18 294 8.6E-36 T 14-10-2018 C2I25_19325 d161d702f55fece894e0de6933f1d262 110 Gene3D G3DSA:1.10.10.10 1 110 9.8E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_19325 d161d702f55fece894e0de6933f1d262 110 SUPERFAMILY SSF46785 11 105 1.22E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19325 d161d702f55fece894e0de6933f1d262 110 Pfam PF03551 Transcriptional regulator PadR-like family 15 86 1.7E-23 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_27345 7b26b410129001d0c1ebda6a77318eaf 363 Pfam PF03845 Spore germination protein 8 328 2.2E-113 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_27345 7b26b410129001d0c1ebda6a77318eaf 363 Gene3D G3DSA:1.20.1740.10 4 268 2.0E-16 T 14-10-2018 C2I25_27345 7b26b410129001d0c1ebda6a77318eaf 363 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 360 1.0E-83 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_04250 fe587b5d09df27fca1d25cadd894d1d2 424 Pfam PF01551 Peptidase family M23 315 412 7.8E-30 T 14-10-2018 IPR016047 Peptidase M23 C2I25_04250 fe587b5d09df27fca1d25cadd894d1d2 424 SUPERFAMILY SSF51261 253 422 6.8E-45 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_04250 fe587b5d09df27fca1d25cadd894d1d2 424 Gene3D G3DSA:1.20.5.1160 33 115 5.3E-6 T 14-10-2018 C2I25_04250 fe587b5d09df27fca1d25cadd894d1d2 424 Gene3D G3DSA:2.70.70.10 244 423 3.0E-40 T 14-10-2018 IPR011055 Duplicated hybrid motif C2I25_22575 20bbd81b213df379d79ac17ab1fc517f 253 Pfam PF02709 N-terminal domain of galactosyltransferase 154 195 2.1E-5 T 14-10-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 C2I25_22575 20bbd81b213df379d79ac17ab1fc517f 253 SUPERFAMILY SSF53448 16 218 5.63E-36 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_22575 20bbd81b213df379d79ac17ab1fc517f 253 Pfam PF00535 Glycosyl transferase family 2 19 125 4.2E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_22575 20bbd81b213df379d79ac17ab1fc517f 253 Gene3D G3DSA:3.90.550.10 2 207 3.7E-36 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_20440 896d9d9aacae5d92b54abb08660d3196 90 Pfam PF04296 Protein of unknown function (DUF448) 9 81 8.2E-28 T 14-10-2018 IPR007393 Domain of unknown function DUF448 C2I25_20440 896d9d9aacae5d92b54abb08660d3196 90 Gene3D G3DSA:3.30.1230.10 1 90 3.3E-35 T 14-10-2018 IPR035931 YlxR-like superfamily C2I25_20440 896d9d9aacae5d92b54abb08660d3196 90 SUPERFAMILY SSF64376 4 87 1.7E-28 T 14-10-2018 IPR035931 YlxR-like superfamily C2I25_24585 f41db51d9cddab64f231616ce3aba3a5 155 Gene3D G3DSA:3.10.180.10 5 130 5.0E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24585 f41db51d9cddab64f231616ce3aba3a5 155 SUPERFAMILY SSF54593 6 138 2.01E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24585 f41db51d9cddab64f231616ce3aba3a5 155 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 128 1.0E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_25800 57d26317653d1c894bbc0185d8dddc92 428 Hamap MF_01970 Kynureninase [kynU]. 3 412 39.892 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 C2I25_25800 57d26317653d1c894bbc0185d8dddc92 428 SUPERFAMILY SSF53383 10 414 1.09E-72 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_25800 57d26317653d1c894bbc0185d8dddc92 428 Gene3D G3DSA:3.90.1150.10 17 412 1.1E-140 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_25800 57d26317653d1c894bbc0185d8dddc92 428 TIGRFAM TIGR01814 kynureninase: kynureninase 14 413 7.8E-122 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 C2I25_25800 57d26317653d1c894bbc0185d8dddc92 428 Pfam PF00266 Aminotransferase class-V 85 376 3.2E-18 T 14-10-2018 IPR000192 Aminotransferase class V domain C2I25_25800 57d26317653d1c894bbc0185d8dddc92 428 PIRSF PIRSF038800 6 420 2.2E-152 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 C2I25_25800 57d26317653d1c894bbc0185d8dddc92 428 Gene3D G3DSA:3.40.640.10 47 316 1.1E-140 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_18745 5b56fb17101575f0c5c36360977e7c3b 317 Gene3D G3DSA:3.60.15.10 1 259 4.6E-50 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_18745 5b56fb17101575f0c5c36360977e7c3b 317 SMART SM00849 17 231 8.4E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_18745 5b56fb17101575f0c5c36360977e7c3b 317 SUPERFAMILY SSF56281 4 300 4.85E-44 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_18745 5b56fb17101575f0c5c36360977e7c3b 317 Pfam PF00753 Metallo-beta-lactamase superfamily 17 231 1.7E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_12780 cfb1965676d83418e6ed1177ad23adc8 132 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 44 123 4.1E-45 T 14-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID C2I25_12780 cfb1965676d83418e6ed1177ad23adc8 132 ProSitePatterns PS00894 DeoR-type HTH domain signature. 50 83 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 C2I25_12780 cfb1965676d83418e6ed1177ad23adc8 132 Pfam PF12116 Stage III sporulation protein D 44 124 9.4E-41 T 14-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID C2I25_12780 cfb1965676d83418e6ed1177ad23adc8 132 Gene3D G3DSA:1.10.10.60 43 132 2.6E-42 T 14-10-2018 C2I25_24425 1897bd06b487f80ac86742159e056ab8 212 Gene3D G3DSA:3.40.109.10 2 212 6.0E-64 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_24425 1897bd06b487f80ac86742159e056ab8 212 Pfam PF00881 Nitroreductase family 15 192 4.7E-33 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_24425 1897bd06b487f80ac86742159e056ab8 212 SUPERFAMILY SSF55469 9 210 6.67E-61 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_14430 492e0f61d06907844642d874eeac098b 109 SUPERFAMILY SSF140500 53 104 1.44E-15 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_14430 492e0f61d06907844642d874eeac098b 109 Gene3D G3DSA:1.20.58.990 53 109 1.1E-26 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_14430 492e0f61d06907844642d874eeac098b 109 Pfam PF09388 Spo0E like sporulation regulatory protein 58 96 1.1E-14 T 14-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I25_15120 34a75ea1ddca37bffd81bbfeff35dfaa 162 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 127 159 5.9E-4 T 14-10-2018 C2I25_06670 828c91f34b1587621e1d9e6c72e28402 181 Pfam PF13302 Acetyltransferase (GNAT) domain 8 152 2.7E-23 T 14-10-2018 IPR000182 GNAT domain C2I25_06670 828c91f34b1587621e1d9e6c72e28402 181 Gene3D G3DSA:3.40.630.30 2 178 1.1E-47 T 14-10-2018 C2I25_06670 828c91f34b1587621e1d9e6c72e28402 181 SUPERFAMILY SSF55729 2 176 1.14E-44 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01655 7443adaa76f044381f33af28e31e3661 46 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 16 38 8.8E-10 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_01655 7443adaa76f044381f33af28e31e3661 46 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 18 40 5.3E-8 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_26975 fd565ec02ec3260c7c12d40ee8010635 113 Pfam PF03551 Transcriptional regulator PadR-like family 15 86 1.0E-17 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_26975 fd565ec02ec3260c7c12d40ee8010635 113 SUPERFAMILY SSF46785 11 104 6.36E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_26975 fd565ec02ec3260c7c12d40ee8010635 113 Gene3D G3DSA:1.10.10.10 2 110 2.0E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01080 2b2f51060541c994e26cc666f5aeee33 69 Pfam PF13063 Protein of unknown function (DUF3925) 1 65 1.7E-45 T 14-10-2018 IPR025168 Protein of unknown function DUF3925 C2I25_12940 9def79136b211074799066040f769f81 158 Pfam PF06338 ComK protein 6 155 4.7E-48 T 14-10-2018 IPR010461 Competence protein ComK GO:0030420 C2I25_12940 9def79136b211074799066040f769f81 158 PIRSF PIRSF011560 1 158 4.2E-56 T 14-10-2018 IPR010461 Competence protein ComK GO:0030420 C2I25_12730 8e29faeca62d90782a4f076040d61c48 506 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 9 485 17.17 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 C2I25_12730 8e29faeca62d90782a4f076040d61c48 506 Pfam PF00361 Proton-conducting membrane transporter 129 427 7.7E-69 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12730 8e29faeca62d90782a4f076040d61c48 506 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 12 483 2.5E-114 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 C2I25_05075 9d4281c610237e1d95bdebfe34a5ae6a 53 SUPERFAMILY SSF51735 7 52 3.6E-11 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_05075 9d4281c610237e1d95bdebfe34a5ae6a 53 Gene3D G3DSA:3.40.50.720 2 53 6.2E-10 T 14-10-2018 C2I25_05075 9d4281c610237e1d95bdebfe34a5ae6a 53 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 51 3.4E-10 T 14-10-2018 C2I25_09000 d86aec1ac7eedd8b6bd45289cb61032d 52 Pfam PF08176 Small acid-soluble spore protein K family 1 48 6.4E-25 T 14-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 C2I25_09000 d86aec1ac7eedd8b6bd45289cb61032d 52 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 1 50 16.381 T 14-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 C2I25_09000 d86aec1ac7eedd8b6bd45289cb61032d 52 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 17 48 1.9E-22 T 14-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 C2I25_17370 af4ce909284269f40d6629b9de522f23 426 Pfam PF01136 Peptidase family U32 91 325 3.8E-84 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 C2I25_17370 af4ce909284269f40d6629b9de522f23 426 Gene3D G3DSA:2.40.30.10 336 423 4.1E-39 T 14-10-2018 C2I25_17370 af4ce909284269f40d6629b9de522f23 426 ProSitePatterns PS01276 Peptidase family U32 signature. 177 195 - T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 C2I25_17370 af4ce909284269f40d6629b9de522f23 426 Pfam PF16325 Peptidase family U32 C-terminal domain 340 421 1.5E-26 T 14-10-2018 IPR032525 Peptidase family U32, C-terminal C2I25_20835 1ba225791c48dc533c9af4e03d63d66e 321 Pfam PF01497 Periplasmic binding protein 64 292 1.2E-34 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_20835 1ba225791c48dc533c9af4e03d63d66e 321 SUPERFAMILY SSF53807 50 314 3.02E-58 T 14-10-2018 C2I25_20835 1ba225791c48dc533c9af4e03d63d66e 321 Gene3D G3DSA:3.40.50.1980 168 321 5.0E-41 T 14-10-2018 C2I25_20835 1ba225791c48dc533c9af4e03d63d66e 321 Gene3D G3DSA:3.40.50.1980 43 167 1.5E-31 T 14-10-2018 C2I25_07915 b644a2da2865419046172262f89585d8 85 Pfam PF04023 FeoA domain 8 76 4.5E-19 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 C2I25_07915 b644a2da2865419046172262f89585d8 85 SUPERFAMILY SSF50037 10 76 1.03E-18 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal C2I25_07915 b644a2da2865419046172262f89585d8 85 Gene3D G3DSA:2.30.30.90 4 79 1.4E-23 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain C2I25_07915 b644a2da2865419046172262f89585d8 85 SMART SM00899 7 79 1.8E-20 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 C2I25_02455 f52b7d4697a2cb2f9999d5e2da98a6cf 213 Gene3D G3DSA:1.20.1280.250 1 84 2.9E-13 T 14-10-2018 IPR038344 EF-G binding protein, N-terminal domain superfamily C2I25_02455 f52b7d4697a2cb2f9999d5e2da98a6cf 213 Pfam PF07299 Elongation factor G-binding protein, N-terminal 4 86 1.7E-27 T 14-10-2018 IPR010841 Elongation factor G-binding protein, N-terminal C2I25_02455 f52b7d4697a2cb2f9999d5e2da98a6cf 213 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 99 204 9.4E-10 T 14-10-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger C2I25_05680 19b16c1dc56e712699e9d9065427cecb 68 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 68 3.0E-21 T 14-10-2018 IPR024255 Spore germination GerPB C2I25_05680 19b16c1dc56e712699e9d9065427cecb 68 Pfam PF10803 Spore germination GerPB 1 48 5.4E-24 T 14-10-2018 IPR024255 Spore germination GerPB C2I25_08425 2bb2ba641a9af1aba4dbf9d72b47dc46 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 1.3E-27 T 14-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I25_08425 2bb2ba641a9af1aba4dbf9d72b47dc46 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 18.437 T 14-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I25_08425 2bb2ba641a9af1aba4dbf9d72b47dc46 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 5.0E-27 T 14-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I25_08425 2bb2ba641a9af1aba4dbf9d72b47dc46 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 2.1E-23 T 14-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I25_18210 004457f4d937233506e105cfc8b4f513 221 Pfam PF13346 ABC-2 family transporter protein 3 216 3.1E-27 T 14-10-2018 IPR025699 ABC-2 membrane transporter-like C2I25_01475 e548142edb3fb73866d0da1057bd7160 316 Pfam PF10947 Protein of unknown function (DUF2628) 54 150 1.6E-23 T 14-10-2018 IPR024399 Protein of unknown function DUF2628 C2I25_00295 21661a28b31ac61422e59df030f4b73a 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 179 3.4E-35 T 14-10-2018 C2I25_00295 21661a28b31ac61422e59df030f4b73a 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 173 4.5E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I25_00295 21661a28b31ac61422e59df030f4b73a 215 Gene3D G3DSA:1.10.150.240 18 82 1.0E-38 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I25_00295 21661a28b31ac61422e59df030f4b73a 215 Gene3D G3DSA:3.40.50.1000 7 199 1.0E-38 T 14-10-2018 IPR023214 HAD superfamily C2I25_00295 21661a28b31ac61422e59df030f4b73a 215 SUPERFAMILY SSF56784 1 209 1.73E-44 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_03000 b8462ce7bf6bc80eaf4ef80f0596ec84 257 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 134 1.1E-23 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G C2I25_03000 b8462ce7bf6bc80eaf4ef80f0596ec84 257 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 250 4.2E-11 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I25_03000 b8462ce7bf6bc80eaf4ef80f0596ec84 257 SUPERFAMILY SSF117143 101 190 1.05E-12 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like C2I25_03000 b8462ce7bf6bc80eaf4ef80f0596ec84 257 Pfam PF00460 Flagella basal body rod protein 4 34 8.1E-7 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I25_02490 1c3d40319a7c22fc049a4464bd514ae3 178 SUPERFAMILY SSF55729 32 154 1.83E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_02490 1c3d40319a7c22fc049a4464bd514ae3 178 Pfam PF13302 Acetyltransferase (GNAT) domain 35 147 3.0E-11 T 14-10-2018 IPR000182 GNAT domain C2I25_02490 1c3d40319a7c22fc049a4464bd514ae3 178 Gene3D G3DSA:3.40.630.30 12 149 1.2E-23 T 14-10-2018 C2I25_10370 021aa5c49080dc157c8ff43af631e16c 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 73 4.3E-14 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I25_10370 021aa5c49080dc157c8ff43af631e16c 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 307 5.4E-30 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_10370 021aa5c49080dc157c8ff43af631e16c 307 Gene3D G3DSA:1.10.3720.10 85 307 7.4E-23 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10370 021aa5c49080dc157c8ff43af631e16c 307 SUPERFAMILY SSF161098 91 285 5.63E-23 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_05185 6b191d24b264428e95adaa40c2b0e223 499 Pfam PF02652 L-lactate permease 2 491 1.2E-60 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I25_20260 1ae876407cd1c445ecb71bd2b1272e28 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 1.2E-33 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 C2I25_20260 1ae876407cd1c445ecb71bd2b1272e28 77 SUPERFAMILY SSF47336 2 77 1.09E-21 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_20260 1ae876407cd1c445ecb71bd2b1272e28 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 7.9E-15 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I25_20260 1ae876407cd1c445ecb71bd2b1272e28 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.155 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 C2I25_20260 1ae876407cd1c445ecb71bd2b1272e28 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site C2I25_20260 1ae876407cd1c445ecb71bd2b1272e28 77 Gene3D G3DSA:1.10.1200.10 1 77 2.0E-27 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_20260 1ae876407cd1c445ecb71bd2b1272e28 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 77 2.0E-13 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 C2I25_28350 c07193c600bdca411ce43b2f31fb6558 64 Gene3D G3DSA:2.60.40.3750 1 64 6.7E-42 T 14-10-2018 C2I25_17900 e603d807a473adf70bbef72397a368b4 252 Pfam PF06691 Protein of unknown function (DUF1189) 4 243 1.8E-65 T 14-10-2018 IPR009574 Protein of unknown function DUF1189 C2I25_18045 8f5f13bef8207ce1ae6d0914a5613ada 86 Pfam PF13110 Protein of unknown function (DUF3966) 35 84 7.0E-38 T 14-10-2018 IPR025084 Protein of unknown function DUF3966 C2I25_11125 49652cf69bd7133b7d79eb12f28c5f28 354 SUPERFAMILY SSF55931 5 268 2.24E-88 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 C2I25_11125 49652cf69bd7133b7d79eb12f28c5f28 354 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 55 252 8.3E-75 T 14-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 C2I25_11125 49652cf69bd7133b7d79eb12f28c5f28 354 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 350 38.731 T 14-10-2018 IPR023660 Protein arginine kinase GO:0016775 C2I25_11125 49652cf69bd7133b7d79eb12f28c5f28 354 Gene3D G3DSA:3.30.590.10 8 262 2.1E-73 T 14-10-2018 C2I25_11125 49652cf69bd7133b7d79eb12f28c5f28 354 ProSitePatterns PS00112 Phosphagen kinase active site signature. 167 173 - T 14-10-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 C2I25_13160 aa9bbf9a467d7185851a933ff2ebb761 433 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 9 431 1.5E-176 T 14-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 C2I25_13160 aa9bbf9a467d7185851a933ff2ebb761 433 PIRSF PIRSF006351 1 433 5.8E-151 T 14-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I25_13160 aa9bbf9a467d7185851a933ff2ebb761 433 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 9 431 1.5E-176 T 14-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I25_13160 aa9bbf9a467d7185851a933ff2ebb761 433 Pfam PF02378 Phosphotransferase system, EIIC 26 356 4.8E-71 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_03480 260ecaa4fa55f48107a149d84bb070ce 241 Pfam PF00690 Cation transporter/ATPase, N-terminus 39 76 2.8E-6 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I25_03480 260ecaa4fa55f48107a149d84bb070ce 241 SUPERFAMILY SSF81653 125 231 7.19E-22 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I25_03480 260ecaa4fa55f48107a149d84bb070ce 241 SUPERFAMILY SSF81665 37 76 1.31E-5 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I25_03480 260ecaa4fa55f48107a149d84bb070ce 241 Pfam PF00122 E1-E2 ATPase 125 232 4.6E-23 T 14-10-2018 C2I25_03480 260ecaa4fa55f48107a149d84bb070ce 241 Gene3D G3DSA:2.70.150.10 33 237 2.6E-32 T 14-10-2018 C2I25_02960 18a95eefbb64c324137309ce3d489628 201 Gene3D G3DSA:3.40.50.1820 2 196 4.2E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_02960 18a95eefbb64c324137309ce3d489628 201 Pfam PF01738 Dienelactone hydrolase family 4 192 1.1E-16 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 C2I25_02960 18a95eefbb64c324137309ce3d489628 201 SUPERFAMILY SSF53474 6 193 1.92E-20 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_01650 060b2185cda2db8cf9016aa15d62c497 250 Pfam PF09234 Domain of unknown function (DUF1963) 44 248 1.7E-37 T 14-10-2018 IPR015315 Protein of unknown function DUF1963 C2I25_01650 060b2185cda2db8cf9016aa15d62c497 250 SUPERFAMILY SSF103032 14 250 1.96E-58 T 14-10-2018 IPR035948 YwqG-like superfamily C2I25_01650 060b2185cda2db8cf9016aa15d62c497 250 Gene3D G3DSA:2.30.320.10 9 248 1.7E-34 T 14-10-2018 IPR035948 YwqG-like superfamily C2I25_28130 43bc2c50c03c1e5f21c7e01c39d1a930 180 SUPERFAMILY SSF64288 19 173 1.29E-26 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_28130 43bc2c50c03c1e5f21c7e01c39d1a930 180 Gene3D G3DSA:3.40.1410.10 14 177 9.3E-24 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I25_19295 8242e49f421bf11e5ab751c458eace6b 392 Pfam PF00155 Aminotransferase class I and II 34 384 7.4E-68 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I25_19295 8242e49f421bf11e5ab751c458eace6b 392 Gene3D G3DSA:3.90.1150.10 30 384 1.6E-114 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I25_19295 8242e49f421bf11e5ab751c458eace6b 392 Gene3D G3DSA:3.40.640.10 45 286 1.6E-114 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_19295 8242e49f421bf11e5ab751c458eace6b 392 SUPERFAMILY SSF53383 5 387 7.98E-104 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_18810 a801d7c1442f8880be5b26430c0da5f2 183 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 16 168 8.2E-22 T 14-10-2018 IPR018639 Domain of unknown function DUF2062 C2I25_21460 7d3abfd78e2007c5da259aaf5e5b6650 129 Gene3D G3DSA:2.60.40.790 34 117 1.2E-7 T 14-10-2018 IPR008978 HSP20-like chaperone C2I25_21460 7d3abfd78e2007c5da259aaf5e5b6650 129 SUPERFAMILY SSF49764 32 123 3.0E-11 T 14-10-2018 IPR008978 HSP20-like chaperone C2I25_12855 b36f981597bde66afe9767b95da9a4fb 319 SUPERFAMILY SSF53448 2 224 3.99E-58 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_12855 b36f981597bde66afe9767b95da9a4fb 319 Gene3D G3DSA:3.90.550.10 2 200 1.2E-56 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_12855 b36f981597bde66afe9767b95da9a4fb 319 Pfam PF00535 Glycosyl transferase family 2 4 164 1.7E-35 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_00720 f15c3b41ac2d7c29ab60757700bdfe43 54 Pfam PF14553 YqbF, hypothetical protein domain 9 49 1.7E-18 T 14-10-2018 IPR027926 Uncharacterised protein YqbF domain C2I25_00720 f15c3b41ac2d7c29ab60757700bdfe43 54 SUPERFAMILY SSF160059 1 47 3.2E-6 T 14-10-2018 C2I25_28240 d4ef8b37ebaece6dff2fac1ee4b56ca2 296 SUPERFAMILY SSF48179 167 289 7.25E-33 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I25_28240 d4ef8b37ebaece6dff2fac1ee4b56ca2 296 PIRSF PIRSF000103 1 294 5.0E-69 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 C2I25_28240 d4ef8b37ebaece6dff2fac1ee4b56ca2 296 Gene3D G3DSA:3.40.50.720 1 164 6.1E-56 T 14-10-2018 C2I25_28240 d4ef8b37ebaece6dff2fac1ee4b56ca2 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 285 1.6E-31 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 C2I25_28240 d4ef8b37ebaece6dff2fac1ee4b56ca2 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 8.9E-46 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I25_28240 d4ef8b37ebaece6dff2fac1ee4b56ca2 296 Gene3D G3DSA:1.10.1040.10 166 296 2.4E-41 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I25_28240 d4ef8b37ebaece6dff2fac1ee4b56ca2 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 C2I25_28240 d4ef8b37ebaece6dff2fac1ee4b56ca2 296 SUPERFAMILY SSF51735 1 161 2.46E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_14295 a14f33656950c5f2cebc61be55426b40 146 Gene3D G3DSA:1.20.120.580 1 144 4.3E-53 T 14-10-2018 IPR037038 Bsu32300-like superfamily C2I25_14295 a14f33656950c5f2cebc61be55426b40 146 Pfam PF01934 Protein of unknown function DUF86 12 126 1.3E-21 T 14-10-2018 IPR008201 Protein of unknown function DUF86 C2I25_21830 a328b92693d4e981818a8339a3876e10 369 Pfam PF13354 Beta-lactamase enzyme family 60 303 5.4E-15 T 14-10-2018 C2I25_21830 a328b92693d4e981818a8339a3876e10 369 SUPERFAMILY SSF56601 42 349 2.89E-25 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_21830 a328b92693d4e981818a8339a3876e10 369 Gene3D G3DSA:3.40.710.10 31 362 6.8E-36 T 14-10-2018 C2I25_15030 5eb962c6fdab548db9e7a310180fc45b 211 Pfam PF07853 Protein of unknown function (DUF1648) 9 56 1.4E-15 T 14-10-2018 IPR012867 Domain of unknown function DUF1648 C2I25_15030 5eb962c6fdab548db9e7a310180fc45b 211 PIRSF PIRSF038959 1 210 5.0E-51 T 14-10-2018 IPR026272 Immunity protein SdpI C2I25_15030 5eb962c6fdab548db9e7a310180fc45b 211 Pfam PF13630 SdpI/YhfL protein family 133 200 1.2E-22 T 14-10-2018 IPR025962 SdpI/YhfL protein family C2I25_07585 312767e3dfccdca6c752a63b980613fb 433 PIRSF PIRSF005353 1 433 1.9E-159 T 14-10-2018 IPR026033 Purine permease PbuG-like C2I25_07585 312767e3dfccdca6c752a63b980613fb 433 Pfam PF00860 Permease family 14 394 1.5E-61 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I25_20505 c914f977d38b5631b7f8a5444a142954 199 Gene3D G3DSA:3.40.50.1950 1 199 8.4E-61 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I25_20505 c914f977d38b5631b7f8a5444a142954 199 SUPERFAMILY SSF52507 3 180 2.09E-31 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I25_20505 c914f977d38b5631b7f8a5444a142954 199 PIRSF PIRSF001390 1 195 2.2E-81 T 14-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B C2I25_20505 c914f977d38b5631b7f8a5444a142954 199 Pfam PF02441 Flavoprotein 6 159 1.4E-18 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 C2I25_20505 c914f977d38b5631b7f8a5444a142954 199 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 4.3E-106 T 14-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B C2I25_27385 62d73a4ffbfd60b7addfc31e95436ebe 380 Pfam PF03600 Citrate transporter 26 308 7.1E-19 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 C2I25_08210 ab1d82d4472c4e4772a2b75acbda4f7d 321 Gene3D G3DSA:1.10.3720.10 85 314 9.2E-18 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_08210 ab1d82d4472c4e4772a2b75acbda4f7d 321 SUPERFAMILY SSF161098 92 302 3.01E-14 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_08210 ab1d82d4472c4e4772a2b75acbda4f7d 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 319 4.5E-40 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_01690 1397eb671d863f798fca778133fdc364 280 SUPERFAMILY SSF51658 1 259 3.32E-43 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily C2I25_01690 1397eb671d863f798fca778133fdc364 280 Gene3D G3DSA:3.20.20.150 1 280 2.2E-81 T 14-10-2018 C2I25_01690 1397eb671d863f798fca778133fdc364 280 Pfam PF01261 Xylose isomerase-like TIM barrel 22 232 1.3E-28 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain C2I25_04750 0f05ebfbcc5abf5b0a86edaefe744c7b 256 Gene3D G3DSA:3.20.20.370 26 248 1.2E-75 T 14-10-2018 C2I25_04750 0f05ebfbcc5abf5b0a86edaefe744c7b 256 Pfam PF04748 Divergent polysaccharide deacetylase 33 247 2.0E-71 T 14-10-2018 IPR006837 Divergent polysaccharide deacetylase C2I25_04750 0f05ebfbcc5abf5b0a86edaefe744c7b 256 SUPERFAMILY SSF88713 30 247 6.0E-65 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_10600 dba784e4fdc32b353925641c1dd6eef9 572 Pfam PF13139 Domain of unknown function (DUF3981) 13 126 4.1E-73 T 14-10-2018 IPR025043 Domain of unknown function DUF3981 C2I25_00080 c3936412d3f3e5719e499dfb6a1300fd 269 Pfam PF13847 Methyltransferase domain 57 157 2.4E-15 T 14-10-2018 IPR025714 Methyltransferase domain C2I25_00080 c3936412d3f3e5719e499dfb6a1300fd 269 Gene3D G3DSA:3.40.50.150 24 246 5.7E-23 T 14-10-2018 C2I25_00080 c3936412d3f3e5719e499dfb6a1300fd 269 SUPERFAMILY SSF53335 29 167 2.13E-23 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_11465 22b1f30dce6b3d7a14f6c8e15c2f8b2f 473 Gene3D G3DSA:3.90.100.10 375 471 1.1E-20 T 14-10-2018 C2I25_11465 22b1f30dce6b3d7a14f6c8e15c2f8b2f 473 Gene3D G3DSA:3.40.640.10 48 278 9.4E-109 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I25_11465 22b1f30dce6b3d7a14f6c8e15c2f8b2f 473 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 397 453 1.5E-13 T 14-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 C2I25_11465 22b1f30dce6b3d7a14f6c8e15c2f8b2f 473 Gene3D G3DSA:3.90.1150.150 279 361 9.4E-109 T 14-10-2018 C2I25_11465 22b1f30dce6b3d7a14f6c8e15c2f8b2f 473 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 306 1.4E-76 T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 C2I25_11465 22b1f30dce6b3d7a14f6c8e15c2f8b2f 473 SUPERFAMILY SSF55904 331 464 7.19E-28 T 14-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 C2I25_11465 22b1f30dce6b3d7a14f6c8e15c2f8b2f 473 SUPERFAMILY SSF53383 7 362 4.3E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I25_26715 9958f5edc6b80faa039e708c63858a23 91 Pfam PF12728 Helix-turn-helix domain 35 82 7.1E-12 T 14-10-2018 C2I25_27810 cc87353493d43ac8921a542615d31274 194 Pfam PF01810 LysE type translocator 13 193 5.9E-17 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_01605 7b8649acf2031a39eb8149b7c4514409 311 SUPERFAMILY SSF51430 1 309 1.44E-91 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_01605 7b8649acf2031a39eb8149b7c4514409 311 Gene3D G3DSA:3.20.20.100 1 311 4.5E-105 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_01605 7b8649acf2031a39eb8149b7c4514409 311 Pfam PF00248 Aldo/keto reductase family 15 309 6.1E-73 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_01605 7b8649acf2031a39eb8149b7c4514409 311 PRINTS PR00069 Aldo-keto reductase signature 109 127 6.3E-10 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_01605 7b8649acf2031a39eb8149b7c4514409 311 PRINTS PR00069 Aldo-keto reductase signature 174 203 6.3E-10 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_01605 7b8649acf2031a39eb8149b7c4514409 311 PRINTS PR00069 Aldo-keto reductase signature 140 157 6.3E-10 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I25_10880 30e961bb7e73ce9e21cae044775b83fa 60 PIRSF PIRSF002211 1 60 5.0E-29 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10880 30e961bb7e73ce9e21cae044775b83fa 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 1.3E-26 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10880 30e961bb7e73ce9e21cae044775b83fa 60 SUPERFAMILY SSF55129 3 59 9.16E-21 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily C2I25_10880 30e961bb7e73ce9e21cae044775b83fa 60 Gene3D G3DSA:3.30.1390.20 1 59 4.9E-27 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily C2I25_10880 30e961bb7e73ce9e21cae044775b83fa 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.91 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_10880 30e961bb7e73ce9e21cae044775b83fa 60 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 4.0E-20 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain C2I25_01225 743754fb9893350f6a02dd63fa82f25f 281 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 209 1.0E-54 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_01225 743754fb9893350f6a02dd63fa82f25f 281 PIRSF PIRSF006483 1 275 3.6E-67 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_01225 743754fb9893350f6a02dd63fa82f25f 281 Gene3D G3DSA:3.30.70.120 187 261 1.1E-19 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_01225 743754fb9893350f6a02dd63fa82f25f 281 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 267 3.6E-12 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_07990 05ffac6ceef35e4188eb5aeb67ed5a68 103 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 22 92 1.1E-12 T 14-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 C2I25_07990 05ffac6ceef35e4188eb5aeb67ed5a68 103 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 13 103 4.1E-38 T 14-10-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 C2I25_22760 53af6874a48bc69c3abf77492317feac 111 SMART SM00914 65 100 4.6E-8 T 14-10-2018 IPR014957 IDEAL domain C2I25_22760 53af6874a48bc69c3abf77492317feac 111 Gene3D G3DSA:4.10.810.10 70 108 1.0E-5 T 14-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I25_22760 53af6874a48bc69c3abf77492317feac 111 Pfam PF08858 IDEAL domain 74 100 4.3E-7 T 14-10-2018 IPR014957 IDEAL domain C2I25_01425 d2e1ff64a5c78d5572bc64804e7d9b94 313 Pfam PF01544 CorA-like Mg2+ transporter protein 21 311 3.0E-65 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I25_01425 d2e1ff64a5c78d5572bc64804e7d9b94 313 SUPERFAMILY SSF143865 1 248 1.31E-56 T 14-10-2018 C2I25_01425 d2e1ff64a5c78d5572bc64804e7d9b94 313 Gene3D G3DSA:3.30.460.20 5 132 3.6E-26 T 14-10-2018 C2I25_01425 d2e1ff64a5c78d5572bc64804e7d9b94 313 Gene3D G3DSA:1.20.58.340 133 255 6.0E-30 T 14-10-2018 C2I25_01425 d2e1ff64a5c78d5572bc64804e7d9b94 313 SUPERFAMILY SSF144083 249 310 2.62E-15 T 14-10-2018 C2I25_01425 d2e1ff64a5c78d5572bc64804e7d9b94 313 Gene3D G3DSA:1.20.58.340 257 313 4.3E-12 T 14-10-2018 C2I25_20000 1400d5aef2089ffae8a83dde1e71883f 156 Pfam PF04472 Cell division protein SepF 66 137 1.0E-29 T 14-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 C2I25_20000 1400d5aef2089ffae8a83dde1e71883f 156 Gene3D G3DSA:3.30.110.150 59 156 2.1E-32 T 14-10-2018 IPR038594 SepF-like superfamily C2I25_20000 1400d5aef2089ffae8a83dde1e71883f 156 Hamap MF_01197 Cell division protein SepF [sepF]. 1 145 18.524 T 14-10-2018 IPR023052 Cell division protein SepF GO:0090529 C2I25_03870 18484544b9637597c537162430025c26 86 Pfam PF14069 Stage VI sporulation protein F 9 80 7.8E-30 T 14-10-2018 IPR025942 Stage VI sporulation protein F C2I25_25435 8f52b8ad4ace30053c2ecbefdf22c553 127 SUPERFAMILY SSF69118 15 122 1.44E-27 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I25_25435 8f52b8ad4ace30053c2ecbefdf22c553 127 Pfam PF02627 Carboxymuconolactone decarboxylase family 34 116 4.0E-20 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I25_25435 8f52b8ad4ace30053c2ecbefdf22c553 127 Gene3D G3DSA:1.20.1290.10 4 123 8.5E-29 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I25_15180 f0977acbb9533bb5cd9088c7ad9b7f66 272 Pfam PF14042 Domain of unknown function (DUF4247) 29 210 2.9E-35 T 14-10-2018 IPR025341 Protein of unknown function DUF4247 C2I25_03395 7cf207e099a06e1724879534b1659a93 128 Gene3D G3DSA:3.30.420.10 2 128 8.1E-31 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_03395 7cf207e099a06e1724879534b1659a93 128 Pfam PF13456 Reverse transcriptase-like 7 124 3.3E-20 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 C2I25_03395 7cf207e099a06e1724879534b1659a93 128 SUPERFAMILY SSF53098 2 122 6.07E-32 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_27330 85bd3a616509a3d44929b1b906f59e40 471 PIRSF PIRSF006060 5 469 1.3E-91 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_27330 85bd3a616509a3d44929b1b906f59e40 471 Gene3D G3DSA:1.20.1740.10 20 468 2.3E-124 T 14-10-2018 C2I25_27330 85bd3a616509a3d44929b1b906f59e40 471 Pfam PF13520 Amino acid permease 26 441 1.5E-61 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 SUPERFAMILY SSF54534 86 157 1.18E-21 T 14-10-2018 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 158 2.3E-27 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 32.628 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 Gene3D G3DSA:3.10.50.30 79 158 2.4E-26 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 PIRSF PIRSF006092 1 158 1.8E-53 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 SUPERFAMILY SSF46557 5 79 1.02E-27 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 9.4E-33 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 Gene3D G3DSA:1.10.287.180 5 78 2.1E-32 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 C2I25_17380 72e90fc55b676fc9cff0307f08d622ef 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 1.7E-58 T 14-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 C2I25_15535 31fa549e95adfa97487ac0438bfdc3b7 188 Pfam PF00589 Phage integrase family 11 172 9.5E-16 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_15535 31fa549e95adfa97487ac0438bfdc3b7 188 Gene3D G3DSA:1.10.443.10 7 174 1.7E-23 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_15535 31fa549e95adfa97487ac0438bfdc3b7 188 SUPERFAMILY SSF56349 9 178 4.71E-28 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_07725 45ec07507159ec4e3e10e5c60d4036fe 333 Pfam PF09084 NMT1/THI5 like 44 259 8.0E-79 T 14-10-2018 IPR015168 SsuA/THI5-like C2I25_07725 45ec07507159ec4e3e10e5c60d4036fe 333 Gene3D G3DSA:3.40.190.10 37 312 2.3E-96 T 14-10-2018 C2I25_07725 45ec07507159ec4e3e10e5c60d4036fe 333 SUPERFAMILY SSF53850 34 260 1.06E-39 T 14-10-2018 C2I25_07725 45ec07507159ec4e3e10e5c60d4036fe 333 Gene3D G3DSA:3.40.190.10 117 219 2.3E-96 T 14-10-2018 C2I25_17200 6852c90e48e53be220f1fafc0dccd432 215 Gene3D G3DSA:3.30.240.20 80 153 1.7E-27 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_17200 6852c90e48e53be220f1fafc0dccd432 215 Pfam PF04239 Protein of unknown function (DUF421) 88 193 2.8E-37 T 14-10-2018 IPR007353 Protein of unknown function DUF421 C2I25_17200 6852c90e48e53be220f1fafc0dccd432 215 Gene3D G3DSA:3.30.240.20 158 215 2.3E-12 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_14445 9aaff614de0c5031fa90c89a51cb6a03 288 SUPERFAMILY SSF54506 3 284 1.12E-51 T 14-10-2018 C2I25_14445 9aaff614de0c5031fa90c89a51cb6a03 288 Gene3D G3DSA:3.10.310.10 126 274 1.2E-119 T 14-10-2018 C2I25_14445 9aaff614de0c5031fa90c89a51cb6a03 288 Gene3D G3DSA:3.10.310.10 6 280 1.2E-119 T 14-10-2018 C2I25_14445 9aaff614de0c5031fa90c89a51cb6a03 288 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I25_14445 9aaff614de0c5031fa90c89a51cb6a03 288 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 37.877 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I25_14445 9aaff614de0c5031fa90c89a51cb6a03 288 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 283 2.8E-96 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I25_14445 9aaff614de0c5031fa90c89a51cb6a03 288 Pfam PF01678 Diaminopimelate epimerase 6 130 5.2E-31 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I25_14445 9aaff614de0c5031fa90c89a51cb6a03 288 Pfam PF01678 Diaminopimelate epimerase 161 276 8.2E-35 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I25_27495 a08f0f0a7e097a74b8e673e67d230f34 129 SUPERFAMILY SSF159121 26 128 8.76E-32 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_27495 a08f0f0a7e097a74b8e673e67d230f34 129 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 125 3.0E-9 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_27495 a08f0f0a7e097a74b8e673e67d230f34 129 Gene3D G3DSA:2.40.50.480 21 129 3.0E-44 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_27495 a08f0f0a7e097a74b8e673e67d230f34 129 Pfam PF06486 Protein of unknown function (DUF1093) 27 115 1.1E-20 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 2.5E-16 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 598 722 3.6E-38 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 211 345 2.2E-28 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 183 2.2E-19 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 Pfam PF00689 Cation transporting ATPase, C-terminus 716 881 2.9E-51 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 632 648 4.5E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 664 689 4.5E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 604 620 4.5E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 488 506 4.5E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF81653 114 224 9.29E-32 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 Gene3D G3DSA:1.20.1110.10 54 877 0.0 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 Pfam PF00122 E1-E2 ATPase 111 304 2.1E-55 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF56784 322 736 3.82E-65 T 14-10-2018 IPR036412 HAD-like superfamily C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF81665 1 881 2.09E-135 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 53 881 1.3E-216 T 14-10-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 541 9.5E-41 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 668 9.5E-41 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 9.5E-41 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 9.5E-41 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 651 9.5E-41 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 9.5E-41 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 Gene3D G3DSA:3.40.50.1000 321 677 0.0 T 14-10-2018 IPR023214 HAD superfamily C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 SMART SM00831 2 76 2.2E-24 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 Gene3D G3DSA:3.40.1110.10 334 537 0.0 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF81660 332 534 1.07E-57 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 646 3.0E-28 T 14-10-2018 C2I25_20135 0d8d3a8c216ea51fccc919b558bf09e1 907 Gene3D G3DSA:2.70.150.10 16 227 0.0 T 14-10-2018 C2I25_28445 4a44d56088992b6dcfecb2d2908cdc6e 473 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 21 427 3.4E-193 T 14-10-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 C2I25_28445 4a44d56088992b6dcfecb2d2908cdc6e 473 TIGRFAM TIGR00238 TIGR00238: KamA family protein 14 342 5.0E-147 T 14-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase C2I25_28445 4a44d56088992b6dcfecb2d2908cdc6e 473 Pfam PF12544 Lysine-2,3-aminomutase 321 447 6.6E-62 T 14-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain C2I25_28445 4a44d56088992b6dcfecb2d2908cdc6e 473 Gene3D G3DSA:2.40.50.600 349 414 1.2E-21 T 14-10-2018 C2I25_28445 4a44d56088992b6dcfecb2d2908cdc6e 473 Pfam PF13353 4Fe-4S single cluster domain 127 199 4.4E-5 T 14-10-2018 C2I25_28445 4a44d56088992b6dcfecb2d2908cdc6e 473 Gene3D G3DSA:3.20.20.70 63 348 1.7E-117 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_28445 4a44d56088992b6dcfecb2d2908cdc6e 473 SUPERFAMILY SSF102114 114 355 3.27E-32 T 14-10-2018 C2I25_28445 4a44d56088992b6dcfecb2d2908cdc6e 473 PIRSF PIRSF004911 3 401 1.3E-159 T 14-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase C2I25_19345 428d100f12ff4b08c2c0ad912437ba39 205 Gene3D G3DSA:3.40.390.10 18 191 6.3E-5 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 Pfam PF02073 Thermophilic metalloprotease (M29) 4 407 1.1E-158 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 362 384 2.7E-63 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 388 407 2.7E-63 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 155 177 2.7E-63 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 244 263 2.7E-63 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 300 320 2.7E-63 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 14 31 2.7E-63 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 79 98 2.7E-63 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 323 344 2.7E-63 T 14-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 Gene3D G3DSA:3.40.1830.10 1 178 2.2E-64 T 14-10-2018 IPR035097 Peptidase M29, N-terminal C2I25_02260 c78148fc5eb8d2be879a8f72e22c9ac2 409 SUPERFAMILY SSF144052 3 408 7.19E-135 T 14-10-2018 C2I25_08675 6b31af4bbb490b1eab7fc10ca8a0b35a 167 SUPERFAMILY SSF160387 50 159 1.12E-28 T 14-10-2018 C2I25_08675 6b31af4bbb490b1eab7fc10ca8a0b35a 167 Pfam PF05573 NosL 18 145 3.7E-20 T 14-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL C2I25_26080 bf2433c77abf43eda633fec9983a9d15 125 SUPERFAMILY SSF50729 6 124 1.68E-44 T 14-10-2018 C2I25_26080 bf2433c77abf43eda633fec9983a9d15 125 Gene3D G3DSA:2.30.29.50 1 124 7.2E-50 T 14-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily C2I25_26080 bf2433c77abf43eda633fec9983a9d15 125 Pfam PF08000 Bacterial PH domain 3 121 6.1E-49 T 14-10-2018 IPR012544 Bacterial Pleckstrin homology domain C2I25_02170 35e169f36c667b7022b5b366fb8e8d12 226 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 20 220 3.4E-25 T 14-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain C2I25_06760 123dceb93948b66aae081a3ce9043eb2 1697 Pfam PF01935 Domain of unknown function DUF87 1345 1553 1.5E-11 T 14-10-2018 IPR002789 Helicase HerA, central domain C2I25_06760 123dceb93948b66aae081a3ce9043eb2 1697 Gene3D G3DSA:3.40.50.300 1508 1676 2.8E-16 T 14-10-2018 C2I25_06760 123dceb93948b66aae081a3ce9043eb2 1697 Gene3D G3DSA:3.40.50.300 1323 1455 1.4E-9 T 14-10-2018 C2I25_06760 123dceb93948b66aae081a3ce9043eb2 1697 SUPERFAMILY SSF52540 1316 1672 5.25E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_06760 123dceb93948b66aae081a3ce9043eb2 1697 TIGRFAM TIGR03237 dnd_assoc_2: DNA phosphorothioation-dependent restriction protein DptH 3 1283 2.3E-274 T 14-10-2018 IPR017646 DNA phosphorothioation-dependent restriction protein DptH C2I25_14885 fdba335a8e03db5854531ceb48705b3a 317 Pfam PF01040 UbiA prenyltransferase family 38 271 3.1E-35 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 C2I25_14885 fdba335a8e03db5854531ceb48705b3a 317 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 30 306 4.1E-38 T 14-10-2018 C2I25_14885 fdba335a8e03db5854531ceb48705b3a 317 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 21 311 19.539 T 14-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I25_14885 fdba335a8e03db5854531ceb48705b3a 317 PIRSF PIRSF005355 14 316 4.2E-86 T 14-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 48 111 6.1E-10 T 14-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 Gene3D G3DSA:2.60.40.420 116 282 1.2E-40 T 14-10-2018 IPR008972 Cupredoxin C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 Gene3D G3DSA:1.10.287.90 29 115 1.6E-29 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 192 209 2.9E-6 T 14-10-2018 C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 87 99 2.9E-6 T 14-10-2018 C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 2.9E-6 T 14-10-2018 C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 SUPERFAMILY SSF81464 19 120 8.67E-23 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 SUPERFAMILY SSF49503 128 274 5.98E-42 T 14-10-2018 IPR008972 Cupredoxin C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 16 241 1.1E-91 T 14-10-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 C2I25_07975 8f49e88b292481dc75e49758cae1cda9 291 PIRSF PIRSF000292 2 291 4.0E-103 T 14-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 C2I25_23905 6eecf5a6aa9e83904af85fd0766173e1 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 3.5E-16 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_23905 6eecf5a6aa9e83904af85fd0766173e1 145 SUPERFAMILY SSF54593 1 120 2.55E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_23905 6eecf5a6aa9e83904af85fd0766173e1 145 Gene3D G3DSA:3.10.180.10 1 123 9.8E-50 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 28 428 4.8E-106 T 14-10-2018 IPR010071 Amino acid adenylation domain C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 2 503 3.9E-215 T 14-10-2018 IPR010072 D-alanine--D-alanyl carrier protein ligase GO:0005524|GO:0047473|GO:0070395 C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 Gene3D G3DSA:3.40.50.12780 1 397 9.0E-155 T 14-10-2018 C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 Hamap MF_00593 D-alanine--D-alanyl carrier protein ligase [dltA]. 1 504 244.717 T 14-10-2018 IPR010072 D-alanine--D-alanyl carrier protein ligase GO:0005524|GO:0047473|GO:0070395 C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 Gene3D G3DSA:3.30.300.30 398 504 3.4E-32 T 14-10-2018 C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 Pfam PF00501 AMP-binding enzyme 8 404 1.5E-85 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 SUPERFAMILY SSF56801 4 501 6.02E-126 T 14-10-2018 C2I25_04560 d133a1e7700b0f4a94065f5896428157 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 492 1.6E-8 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27485 aa8560d61cf0a5745e50b414305f8fae 269 Gene3D G3DSA:2.30.30.40 34 105 1.3E-5 T 14-10-2018 C2I25_27485 aa8560d61cf0a5745e50b414305f8fae 269 Pfam PF12385 Papain-like cysteine protease AvrRpt2 115 255 1.9E-38 T 14-10-2018 IPR022118 Peptidase C70, AvrRpt2 C2I25_27485 aa8560d61cf0a5745e50b414305f8fae 269 Gene3D G3DSA:3.90.70.10 124 265 2.7E-8 T 14-10-2018 C2I25_05165 98b2cfa7929406d6dcea102f96061196 411 Pfam PF13308 YARHG domain 332 411 6.1E-24 T 14-10-2018 IPR025582 YARHG domain C2I25_05165 98b2cfa7929406d6dcea102f96061196 411 Gene3D G3DSA:1.20.58.1690 326 410 1.2E-24 T 14-10-2018 IPR038434 YARHG domain superfamily C2I25_05165 98b2cfa7929406d6dcea102f96061196 411 Pfam PF13240 zinc-ribbon domain 4 24 2.0E-6 T 14-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 C2I25_05165 98b2cfa7929406d6dcea102f96061196 411 SMART SM01324 331 410 8.7E-28 T 14-10-2018 IPR025582 YARHG domain C2I25_08430 605869b686d8a7c6be84f1414f1da6cf 95 Pfam PF12840 Helix-turn-helix domain 17 72 2.6E-10 T 14-10-2018 C2I25_08430 605869b686d8a7c6be84f1414f1da6cf 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 7.5E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08430 605869b686d8a7c6be84f1414f1da6cf 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 7.5E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08430 605869b686d8a7c6be84f1414f1da6cf 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 7.5E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_08430 605869b686d8a7c6be84f1414f1da6cf 95 SUPERFAMILY SSF46785 7 93 8.56E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08430 605869b686d8a7c6be84f1414f1da6cf 95 Gene3D G3DSA:1.10.10.10 1 94 4.6E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_08430 605869b686d8a7c6be84f1414f1da6cf 95 SMART SM00418 16 95 6.5E-23 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_26000 f461c35fe422610d07c08032863d9406 217 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 151 205 3.2E-16 T 14-10-2018 C2I25_00680 b5e66f6ceb275efb490b00c851f0f0d3 395 Pfam PF01548 Transposase 4 162 8.0E-43 T 14-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 C2I25_00680 b5e66f6ceb275efb490b00c851f0f0d3 395 Pfam PF02371 Transposase IS116/IS110/IS902 family 270 354 1.3E-26 T 14-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 C2I25_24885 e24d154b366971dbdfd3bf644af99e2b 227 Pfam PF08713 DNA alkylation repair enzyme 6 189 2.3E-25 T 14-10-2018 IPR014825 DNA alkylation repair enzyme C2I25_24885 e24d154b366971dbdfd3bf644af99e2b 227 SUPERFAMILY SSF48371 1 224 2.45E-65 T 14-10-2018 IPR016024 Armadillo-type fold C2I25_19570 01626723e6fbe69909174de3ce189e5e 147 Pfam PF00571 CBS domain 86 139 6.6E-6 T 14-10-2018 IPR000644 CBS domain C2I25_19570 01626723e6fbe69909174de3ce189e5e 147 SUPERFAMILY SSF54631 12 140 5.66E-29 T 14-10-2018 C2I25_19570 01626723e6fbe69909174de3ce189e5e 147 Gene3D G3DSA:3.10.580.10 1 147 2.1E-63 T 14-10-2018 C2I25_24135 f0832d10b183d6d64a0919ce012e53aa 795 PIRSF PIRSF007519 1 795 0.0 T 14-10-2018 IPR012300 Peptidase M6, InhA C2I25_24135 f0832d10b183d6d64a0919ce012e53aa 795 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 183 492 9.6E-85 T 14-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I25_24135 f0832d10b183d6d64a0919ce012e53aa 795 Pfam PF05547 Immune inhibitor A peptidase M6 148 791 2.7E-300 T 14-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I25_24135 f0832d10b183d6d64a0919ce012e53aa 795 SUPERFAMILY SSF55486 262 429 6.07E-17 T 14-10-2018 C2I25_08910 102e0cff9243ee754226196427a84d8e 139 SUPERFAMILY SSF55729 12 129 1.18E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_08910 102e0cff9243ee754226196427a84d8e 139 Pfam PF13673 Acetyltransferase (GNAT) domain 27 128 2.5E-16 T 14-10-2018 IPR000182 GNAT domain C2I25_08910 102e0cff9243ee754226196427a84d8e 139 Gene3D G3DSA:3.40.630.30 4 135 5.0E-38 T 14-10-2018 C2I25_03955 b1fc14be8b1ce43d1bb24bbcf3e978df 202 Hamap MF_01124 Adapter protein MecA [mecA]. 1 195 24.584 T 14-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I25_03955 b1fc14be8b1ce43d1bb24bbcf3e978df 202 Gene3D G3DSA:3.30.70.1950 104 196 2.2E-26 T 14-10-2018 IPR038471 MecA, C-terminal domain superfamily C2I25_03955 b1fc14be8b1ce43d1bb24bbcf3e978df 202 Pfam PF05389 Negative regulator of genetic competence (MecA) 101 191 7.7E-14 T 14-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I25_03955 b1fc14be8b1ce43d1bb24bbcf3e978df 202 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 89 6.0E-27 T 14-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I25_03955 b1fc14be8b1ce43d1bb24bbcf3e978df 202 PIRSF PIRSF029008 1 197 1.5E-63 T 14-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I25_28040 b0ae5fe9f7855065aab876b2f9040bd0 290 Gene3D G3DSA:3.60.15.10 3 246 5.0E-36 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_28040 b0ae5fe9f7855065aab876b2f9040bd0 290 SMART SM00849 25 225 3.3E-15 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_28040 b0ae5fe9f7855065aab876b2f9040bd0 290 SUPERFAMILY SSF56281 25 244 2.49E-35 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_28040 b0ae5fe9f7855065aab876b2f9040bd0 290 Pfam PF00753 Metallo-beta-lactamase superfamily 30 225 2.5E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_17095 ef904b6bfbcfc209a09a71036afef370 640 Pfam PF02687 FtsX-like permease family 86 180 9.4E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_17095 ef904b6bfbcfc209a09a71036afef370 640 PIRSF PIRSF018968 1 640 1.8E-127 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_13365 e50bec9ed583b4c910ba681f265984c7 65 Pfam PF01381 Helix-turn-helix 7 61 8.7E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_13365 e50bec9ed583b4c910ba681f265984c7 65 Gene3D G3DSA:1.10.260.40 3 65 1.1E-26 T 14-10-2018 C2I25_13365 e50bec9ed583b4c910ba681f265984c7 65 SUPERFAMILY SSF47413 3 63 5.09E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_13365 e50bec9ed583b4c910ba681f265984c7 65 SMART SM00530 6 61 4.6E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_01665 20cd123ff79f78f6041257c5762336f4 55 Pfam PF13069 Protein of unknown function (DUF3933) 1 52 1.9E-35 T 14-10-2018 IPR025174 Protein of unknown function DUF3933 C2I25_20770 4610bfe77c70462ba388b7d70bb116da 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 230 6.5E-40 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_20770 4610bfe77c70462ba388b7d70bb116da 303 SUPERFAMILY SSF51735 3 295 1.59E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_20770 4610bfe77c70462ba388b7d70bb116da 303 Gene3D G3DSA:3.90.25.10 170 288 1.2E-57 T 14-10-2018 C2I25_20770 4610bfe77c70462ba388b7d70bb116da 303 Gene3D G3DSA:3.40.50.720 8 281 1.2E-57 T 14-10-2018 C2I25_10890 fa26a9fcf000bb97cd454396de6e4d85 120 Gene3D G3DSA:3.30.420.100 5 120 5.7E-48 T 14-10-2018 C2I25_10890 fa26a9fcf000bb97cd454396de6e4d85 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 30.937 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10890 fa26a9fcf000bb97cd454396de6e4d85 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 2.6E-49 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_10890 fa26a9fcf000bb97cd454396de6e4d85 120 SUPERFAMILY SSF53137 7 118 3.49E-56 T 14-10-2018 C2I25_10890 fa26a9fcf000bb97cd454396de6e4d85 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 6.8E-53 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16120 88cf6ba7b83ea6c0fcec7262a9d5da95 211 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 12 155 9.4E-16 T 14-10-2018 IPR014903 Protein of unknown function DUF1796 C2I25_26800 b7b64e05ad32e6c5b71dc112f14c57b9 113 Pfam PF13053 Protein of unknown function (DUF3914) 1 89 7.6E-60 T 14-10-2018 IPR025025 Protein of unknown function DUF3914 C2I25_18405 5f8bc65e61b5067f695fa56a99366525 130 Pfam PF03780 Asp23 family, cell envelope-related function 14 118 6.1E-36 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 C2I25_27350 c06eed2e6f1dffdf9060509444e4d2b6 524 PIRSF PIRSF005690 29 524 3.5E-189 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_27350 c06eed2e6f1dffdf9060509444e4d2b6 524 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 44 513 2.0E-187 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_26425 218764e62b8fad47ff289fa7d214050d 708 SUPERFAMILY SSF56519 57 320 2.88E-37 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I25_26425 218764e62b8fad47ff289fa7d214050d 708 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 684 8.2E-71 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I25_26425 218764e62b8fad47ff289fa7d214050d 708 Gene3D G3DSA:3.40.710.10 320 679 6.7E-221 T 14-10-2018 C2I25_26425 218764e62b8fad47ff289fa7d214050d 708 Gene3D G3DSA:3.90.1310.30 62 573 6.7E-221 T 14-10-2018 C2I25_26425 218764e62b8fad47ff289fa7d214050d 708 Gene3D G3DSA:1.10.10.1230 87 196 6.7E-221 T 14-10-2018 C2I25_26425 218764e62b8fad47ff289fa7d214050d 708 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 305 1.3E-35 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I25_26425 218764e62b8fad47ff289fa7d214050d 708 SUPERFAMILY SSF56601 321 692 5.63E-71 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_21780 81118cbdcc505e25c2a1d20fc815fd1b 82 PIRSF PIRSF002599 2 82 4.0E-11 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I25_21780 81118cbdcc505e25c2a1d20fc815fd1b 82 Pfam PF06961 Protein of unknown function (DUF1294) 10 64 1.4E-25 T 14-10-2018 IPR010718 Protein of unknown function DUF1294 C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Gene3D G3DSA:3.90.650.10 569 739 1.2E-40 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 359 2.4E-34 T 14-10-2018 IPR010918 PurM-like, C-terminal domain C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 710 3.0E-13 T 14-10-2018 IPR010918 PurM-like, C-terminal domain C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 SUPERFAMILY SSF55326 401 570 1.96E-57 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 PIRSF PIRSF001587 8 739 0.0 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Gene3D G3DSA:3.90.650.10 34 362 2.8E-136 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 SUPERFAMILY SSF55326 18 201 1.94E-53 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 SUPERFAMILY SSF56042 205 430 1.03E-56 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 737 0.0 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 SUPERFAMILY SSF56042 571 738 5.23E-38 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Gene3D G3DSA:3.30.1330.10 392 565 3.0E-62 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 739 330.807 T 14-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 562 2.7E-26 T 14-10-2018 IPR016188 PurM-like, N-terminal domain C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 1.1E-25 T 14-10-2018 IPR016188 PurM-like, N-terminal domain C2I25_09910 1161ceb40e4d560d0f411d32a2cebb0b 739 Gene3D G3DSA:3.30.1330.10 49 197 2.8E-136 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I25_22195 8ea64687928b876207921ac4adccbe5f 488 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 474 46.515 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 C2I25_22195 8ea64687928b876207921ac4adccbe5f 488 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 12 458 1.4E-122 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 C2I25_09195 53bb9e64f50965f9ff43e4917e0a2422 265 Pfam PF14167 YfkD-like protein 34 263 1.9E-105 T 14-10-2018 IPR025548 YfkD-like protein C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 Gene3D G3DSA:1.20.1250.20 1 204 3.8E-28 T 14-10-2018 C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 Pfam PF07690 Major Facilitator Superfamily 229 382 4.7E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 Pfam PF07690 Major Facilitator Superfamily 10 221 2.3E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 SUPERFAMILY SSF103473 3 387 5.62E-60 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 131 152 3.1E-5 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 92 110 3.1E-5 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 44 62 3.1E-5 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 279 302 3.1E-5 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_15550 6f41385ff59727fba9725f71ee5cb9cd 397 Gene3D G3DSA:1.20.1250.20 205 389 3.0E-22 T 14-10-2018 C2I25_21215 c3536371e56b7b1c236af2a101b7c306 322 SUPERFAMILY SSF53335 58 277 7.74E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_21215 c3536371e56b7b1c236af2a101b7c306 322 Pfam PF08241 Methyltransferase domain 104 196 1.4E-18 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_21215 c3536371e56b7b1c236af2a101b7c306 322 Gene3D G3DSA:3.40.50.150 72 236 1.7E-29 T 14-10-2018 C2I25_13980 32ebac7d5f490842697e2e0cf262ec7a 260 Pfam PF02096 60Kd inner membrane protein 61 248 8.5E-55 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I25_13980 32ebac7d5f490842697e2e0cf262ec7a 260 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 251 30.234 T 14-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 C2I25_13980 32ebac7d5f490842697e2e0cf262ec7a 260 PRINTS PR00701 60kDa inner membrane protein signature 214 237 1.2E-13 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I25_13980 32ebac7d5f490842697e2e0cf262ec7a 260 PRINTS PR00701 60kDa inner membrane protein signature 128 151 1.2E-13 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I25_13980 32ebac7d5f490842697e2e0cf262ec7a 260 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 60 247 1.8E-61 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_18510 b49642ebf726cf28d709367f6e968d13 492 Gene3D G3DSA:3.30.2400.10 282 479 7.8E-14 T 14-10-2018 C2I25_18510 b49642ebf726cf28d709367f6e968d13 492 Pfam PF04586 Caudovirus prohead serine protease 14 166 5.7E-38 T 14-10-2018 IPR006433 Prohead protease C2I25_18510 b49642ebf726cf28d709367f6e968d13 492 Pfam PF05065 Phage capsid family 221 488 3.2E-43 T 14-10-2018 IPR024455 Phage capsid C2I25_18510 b49642ebf726cf28d709367f6e968d13 492 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 181 488 1.5E-63 T 14-10-2018 IPR024455 Phage capsid C2I25_18510 b49642ebf726cf28d709367f6e968d13 492 SUPERFAMILY SSF56563 215 489 2.22E-52 T 14-10-2018 C2I25_18510 b49642ebf726cf28d709367f6e968d13 492 Gene3D G3DSA:3.30.2320.10 348 484 7.8E-14 T 14-10-2018 C2I25_18510 b49642ebf726cf28d709367f6e968d13 492 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 24 163 2.0E-27 T 14-10-2018 IPR006433 Prohead protease C2I25_21040 264d32b85ec4c3ba8218eb7f70faca7d 79 Hamap MF_01103 UPF0291 protein . 2 60 16.358 T 14-10-2018 IPR009242 Protein of unknown function DUF896 C2I25_21040 264d32b85ec4c3ba8218eb7f70faca7d 79 Gene3D G3DSA:1.10.287.540 1 57 8.9E-21 T 14-10-2018 C2I25_21040 264d32b85ec4c3ba8218eb7f70faca7d 79 SUPERFAMILY SSF158221 1 42 2.35E-13 T 14-10-2018 C2I25_21040 264d32b85ec4c3ba8218eb7f70faca7d 79 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 1.0E-27 T 14-10-2018 IPR009242 Protein of unknown function DUF896 C2I25_01045 f16400359a0dbab32bfd5ab29aa900c6 176 Gene3D G3DSA:1.10.4070.10 65 153 8.7E-13 T 14-10-2018 C2I25_01045 f16400359a0dbab32bfd5ab29aa900c6 176 Gene3D G3DSA:1.20.120.700 13 161 8.7E-13 T 14-10-2018 C2I25_01045 f16400359a0dbab32bfd5ab29aa900c6 176 SUPERFAMILY SSF89155 9 168 2.35E-22 T 14-10-2018 IPR036411 TorD-like superfamily C2I25_01045 f16400359a0dbab32bfd5ab29aa900c6 176 Pfam PF02613 Nitrate reductase delta subunit 41 147 4.9E-7 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone C2I25_01045 f16400359a0dbab32bfd5ab29aa900c6 176 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 13 163 4.0E-40 T 14-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 C2I25_09090 60c9ddafa7475bad098899c65a06e7f9 423 Pfam PF00144 Beta-lactamase 125 406 8.6E-56 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_09090 60c9ddafa7475bad098899c65a06e7f9 423 SUPERFAMILY SSF56601 113 418 7.36E-80 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_09090 60c9ddafa7475bad098899c65a06e7f9 423 Gene3D G3DSA:3.40.710.10 111 412 6.7E-82 T 14-10-2018 C2I25_11710 b00f75b4f3deb0375f9ed387088dd6fc 65 PIRSF PIRSF037263 1 65 8.6E-35 T 14-10-2018 IPR009296 Protein of unknown function DUF951 C2I25_11710 b00f75b4f3deb0375f9ed387088dd6fc 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 6 60 1.8E-29 T 14-10-2018 IPR009296 Protein of unknown function DUF951 C2I25_00125 3e3ee323d612ea19bbe467fff9537d5d 349 SUPERFAMILY SSF161098 86 282 9.81E-10 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_00125 3e3ee323d612ea19bbe467fff9537d5d 349 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 303 1.5E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_00125 3e3ee323d612ea19bbe467fff9537d5d 349 Gene3D G3DSA:1.10.3720.10 80 311 4.2E-10 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_19385 6f20faaba0dff273d6987f6f8713cebf 151 Pfam PF06271 RDD family 9 144 1.6E-24 T 14-10-2018 IPR010432 RDD C2I25_27030 8ac1a1095cab7d6dab6219d7e80cc294 211 Pfam PF13460 NAD(P)H-binding 11 199 2.9E-34 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_27030 8ac1a1095cab7d6dab6219d7e80cc294 211 SUPERFAMILY SSF51735 5 209 1.52E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_27030 8ac1a1095cab7d6dab6219d7e80cc294 211 Gene3D G3DSA:3.40.50.720 2 209 2.9E-38 T 14-10-2018 C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 Gene3D G3DSA:3.40.80.10 157 315 9.1E-46 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 SUPERFAMILY SSF55846 157 317 2.22E-45 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 SMART SM00644 167 305 4.7E-26 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 Pfam PF00395 S-layer homology domain 427 466 1.2E-9 T 14-10-2018 IPR001119 S-layer homology domain C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 Pfam PF00395 S-layer homology domain 481 524 4.8E-8 T 14-10-2018 IPR001119 S-layer homology domain C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 Pfam PF00395 S-layer homology domain 545 587 2.8E-7 T 14-10-2018 IPR001119 S-layer homology domain C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 Gene3D G3DSA:2.30.30.40 339 409 6.0E-9 T 14-10-2018 C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 Pfam PF08239 Bacterial SH3 domain 354 396 3.7E-6 T 14-10-2018 IPR003646 SH3-like domain, bacterial-type C2I25_23410 2fa9ddd0f7e19ad237c9f6a4f49727a3 599 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 176 298 2.3E-23 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I25_02720 db0bebf91e72a5878a9ecd8f3b283eb5 237 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 13 216 3.7E-54 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 C2I25_07140 5360bf95459b7213f2b63503393a970d 183 Pfam PF07366 SnoaL-like polyketide cyclase 63 177 3.5E-31 T 14-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 C2I25_07140 5360bf95459b7213f2b63503393a970d 183 Gene3D G3DSA:3.10.450.50 25 183 6.1E-54 T 14-10-2018 C2I25_07140 5360bf95459b7213f2b63503393a970d 183 SUPERFAMILY SSF54427 61 180 3.13E-29 T 14-10-2018 IPR032710 NTF2-like domain superfamily C2I25_27170 33e72574137e9c34dbc50818f47184f3 280 SUPERFAMILY SSF56300 42 278 3.28E-36 T 14-10-2018 C2I25_27170 33e72574137e9c34dbc50818f47184f3 280 Gene3D G3DSA:3.60.21.10 48 235 2.2E-29 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_27170 33e72574137e9c34dbc50818f47184f3 280 Pfam PF00149 Calcineurin-like phosphoesterase 49 218 3.4E-16 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_03995 04b4f86d419b3a57ffea99caf65d9d86 192 Pfam PF12822 ECF transporter, substrate-specific component 9 177 1.6E-22 T 14-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 C2I25_03995 04b4f86d419b3a57ffea99caf65d9d86 192 PIRSF PIRSF037778 3 190 1.5E-41 T 14-10-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 C2I25_03995 04b4f86d419b3a57ffea99caf65d9d86 192 Gene3D G3DSA:1.10.1760.20 1 186 4.8E-51 T 14-10-2018 C2I25_20220 27b590500fc863f27e79ec28caedbc1d 62 Gene3D G3DSA:2.30.170.40 19 62 6.8E-18 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20220 27b590500fc863f27e79ec28caedbc1d 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.58 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20220 27b590500fc863f27e79ec28caedbc1d 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 6.8E-23 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_20220 27b590500fc863f27e79ec28caedbc1d 62 Pfam PF00830 Ribosomal L28 family 3 58 2.0E-20 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_20220 27b590500fc863f27e79ec28caedbc1d 62 SUPERFAMILY SSF143800 1 60 3.73E-23 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_19290 c1f0e3497b9358bed2c755ad0e994f8a 414 Gene3D G3DSA:3.20.20.110 122 414 1.5E-102 T 14-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I25_19290 c1f0e3497b9358bed2c755ad0e994f8a 414 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 406 62.423 T 14-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 C2I25_19290 c1f0e3497b9358bed2c755ad0e994f8a 414 SUPERFAMILY SSF51649 121 411 2.22E-79 T 14-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I25_19290 c1f0e3497b9358bed2c755ad0e994f8a 414 SUPERFAMILY SSF54966 2 121 3.57E-30 T 14-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I25_19290 c1f0e3497b9358bed2c755ad0e994f8a 414 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 127 403 8.6E-35 T 14-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I25_19290 c1f0e3497b9358bed2c755ad0e994f8a 414 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 406 1.3E-237 T 14-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 C2I25_19290 c1f0e3497b9358bed2c755ad0e994f8a 414 Gene3D G3DSA:3.30.70.150 1 121 7.2E-32 T 14-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I25_19290 c1f0e3497b9358bed2c755ad0e994f8a 414 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 3 101 4.7E-5 T 14-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I25_23835 4f208c187001773fcc512df5fa5bdc80 759 Pfam PF13086 AAA domain 164 374 2.1E-27 T 14-10-2018 C2I25_23835 4f208c187001773fcc512df5fa5bdc80 759 Gene3D G3DSA:3.40.50.300 89 394 3.8E-46 T 14-10-2018 C2I25_23835 4f208c187001773fcc512df5fa5bdc80 759 Gene3D G3DSA:3.40.50.300 416 626 1.5E-33 T 14-10-2018 C2I25_23835 4f208c187001773fcc512df5fa5bdc80 759 Pfam PF13087 AAA domain 406 590 3.0E-28 T 14-10-2018 C2I25_23835 4f208c187001773fcc512df5fa5bdc80 759 SUPERFAMILY SSF52540 157 624 3.12E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_15885 5590a0b79d08bbc35e4dbce393c4309d 209 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 1 203 8.6E-97 T 14-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 C2I25_15885 5590a0b79d08bbc35e4dbce393c4309d 209 Pfam PF00793 DAHP synthetase I family 2 203 7.1E-65 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I25_15885 5590a0b79d08bbc35e4dbce393c4309d 209 Gene3D G3DSA:3.20.20.70 1 208 2.6E-78 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_15885 5590a0b79d08bbc35e4dbce393c4309d 209 SUPERFAMILY SSF51569 1 204 1.19E-76 T 14-10-2018 C2I25_11130 ebf632a00a29e392c4389a0c2096edff 182 PIRSF PIRSF015034 1 182 1.1E-61 T 14-10-2018 IPR025542 YacH protein C2I25_11130 ebf632a00a29e392c4389a0c2096edff 182 SUPERFAMILY SSF46600 138 174 2.88E-6 T 14-10-2018 IPR036876 UVR domain superfamily C2I25_11130 ebf632a00a29e392c4389a0c2096edff 182 Pfam PF02151 UvrB/uvrC motif 139 173 9.9E-7 T 14-10-2018 IPR001943 UVR domain GO:0005515 C2I25_19500 6099ebd75d12a6039604b1eb07e0efff 220 SUPERFAMILY SSF140423 21 211 6.54E-57 T 14-10-2018 IPR036785 YkyA-like superfamily C2I25_19500 6099ebd75d12a6039604b1eb07e0efff 220 Pfam PF10368 Putative cell-wall binding lipoprotein 13 213 1.8E-63 T 14-10-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like C2I25_19500 6099ebd75d12a6039604b1eb07e0efff 220 Gene3D G3DSA:1.20.120.570 13 209 8.1E-40 T 14-10-2018 IPR036785 YkyA-like superfamily C2I25_12185 1264c56d640e91d40931ddafaeeb423b 97 Pfam PF12823 Domain of unknown function (DUF3817) 7 93 8.3E-21 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane C2I25_12185 1264c56d640e91d40931ddafaeeb423b 97 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 10 92 1.4E-26 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane C2I25_21745 cafb891e08bdd4cd3739f29dddcbb04a 338 Pfam PF00899 ThiF family 5 241 3.6E-63 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I25_21745 cafb891e08bdd4cd3739f29dddcbb04a 338 SUPERFAMILY SSF69572 3 328 8.89E-89 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I25_21745 cafb891e08bdd4cd3739f29dddcbb04a 338 Gene3D G3DSA:3.40.50.720 1 250 4.5E-75 T 14-10-2018 C2I25_15360 3572942666b0e05fa9c1199bc60eebc4 242 Pfam PF13731 WxL domain surface cell wall-binding 28 241 4.0E-59 T 14-10-2018 IPR027994 WxL domain C2I25_12905 f0b3e02875a044dbb4d6eb39e6131dc7 170 Pfam PF11683 Protein of unknown function (DUF3278) 16 124 1.8E-10 T 14-10-2018 IPR021697 Protein of unknown function DUF3278 C2I25_09365 925a9d9585671942134bda5d708187ef 104 Gene3D G3DSA:3.40.30.10 1 104 9.0E-21 T 14-10-2018 C2I25_09365 925a9d9585671942134bda5d708187ef 104 SUPERFAMILY SSF52833 3 100 1.2E-14 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_09365 925a9d9585671942134bda5d708187ef 104 Pfam PF00085 Thioredoxin 12 99 5.7E-5 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I25_21960 3974cc4c5e38c18003d2e71dc9311943 247 Gene3D G3DSA:3.30.1380.10 57 247 2.3E-82 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_21960 3974cc4c5e38c18003d2e71dc9311943 247 SUPERFAMILY SSF55166 84 231 3.14E-37 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I25_21960 3974cc4c5e38c18003d2e71dc9311943 247 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 100 228 3.9E-48 T 14-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 C2I25_17155 ddf689ebff3b33d8c9383885680722d7 176 Pfam PF08977 Bypass of Forespore C, N terminal 39 89 4.7E-21 T 14-10-2018 IPR015071 Bypass-of-forespore C, N-terminal C2I25_17155 ddf689ebff3b33d8c9383885680722d7 176 Pfam PF08955 BofC C-terminal domain 91 163 1.9E-24 T 14-10-2018 IPR015050 Bypass of forespore C, C-terminal C2I25_17155 ddf689ebff3b33d8c9383885680722d7 176 Gene3D G3DSA:3.30.70.1740 91 167 5.3E-29 T 14-10-2018 IPR038117 Bypass of forespore C, C-terminal domain superfamily C2I25_17155 ddf689ebff3b33d8c9383885680722d7 176 Gene3D G3DSA:3.10.20.420 37 90 1.6E-15 T 14-10-2018 IPR038118 Bypass-of-forespore C, N-terminal domain superfamily C2I25_07600 1db602aa707f68a1b40954e59a80fc19 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 321 6.9E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 SUPERFAMILY SSF50249 8 149 2.36E-43 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 15 497 46.235 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 494 3.3E-82 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 Gene3D G3DSA:2.40.50.140 9 149 1.0E-44 T 14-10-2018 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 8 497 7.9E-223 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 Pfam PF01336 OB-fold nucleic acid binding domain 63 140 1.6E-14 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 Gene3D G3DSA:3.30.930.10 150 494 5.4E-137 T 14-10-2018 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 PIRSF PIRSF039101 2 499 1.2E-199 T 14-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 SUPERFAMILY SSF55681 156 495 4.58E-123 T 14-10-2018 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 1.6E-39 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 1.6E-39 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 1.6E-39 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 379 395 1.6E-39 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_11215 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 1.6E-39 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I25_16790 e494fd27d13a539d99a85c375b5fd519 143 SUPERFAMILY SSF46785 3 137 4.85E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_16790 e494fd27d13a539d99a85c375b5fd519 143 Pfam PF02082 Transcriptional regulator 1 81 6.7E-24 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type C2I25_16790 e494fd27d13a539d99a85c375b5fd519 143 Gene3D G3DSA:1.10.10.10 1 143 1.9E-58 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_12740 8fe456fb05e009509efda7651b4c209a 236 Gene3D G3DSA:3.30.360.40 163 236 1.5E-27 T 14-10-2018 C2I25_12740 8fe456fb05e009509efda7651b4c209a 236 Gene3D G3DSA:3.30.2030.10 32 162 3.3E-19 T 14-10-2018 C2I25_12740 8fe456fb05e009509efda7651b4c209a 236 SUPERFAMILY SSF143842 32 233 1.44E-51 T 14-10-2018 IPR036209 YwmB-like superfamily C2I25_12740 8fe456fb05e009509efda7651b4c209a 236 Pfam PF08680 TATA-box binding 48 236 1.2E-46 T 14-10-2018 IPR014794 TATA-box binding C2I25_14515 01a0506ec31e811ea77eac3e19830112 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 5.8E-6 T 14-10-2018 C2I25_14515 01a0506ec31e811ea77eac3e19830112 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 5.8E-6 T 14-10-2018 C2I25_14515 01a0506ec31e811ea77eac3e19830112 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.8E-6 T 14-10-2018 C2I25_14515 01a0506ec31e811ea77eac3e19830112 403 SUPERFAMILY SSF51905 4 208 8.37E-27 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_14515 01a0506ec31e811ea77eac3e19830112 403 Gene3D G3DSA:3.50.50.100 2 403 4.7E-133 T 14-10-2018 C2I25_14515 01a0506ec31e811ea77eac3e19830112 403 SUPERFAMILY SSF51905 152 333 1.14E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_14515 01a0506ec31e811ea77eac3e19830112 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 323 1.7E-44 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_21625 121f2661e9fe746716d220651832910d 565 PIRSF PIRSF002741 3 565 1.9E-106 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I25_21625 121f2661e9fe746716d220651832910d 565 SUPERFAMILY SSF53850 49 558 5.57E-124 T 14-10-2018 C2I25_21625 121f2661e9fe746716d220651832910d 565 Gene3D G3DSA:3.90.76.10 85 207 3.1E-182 T 14-10-2018 C2I25_21625 121f2661e9fe746716d220651832910d 565 Gene3D G3DSA:3.10.105.10 308 535 3.1E-182 T 14-10-2018 C2I25_21625 121f2661e9fe746716d220651832910d 565 Gene3D G3DSA:3.40.190.10 66 550 3.1E-182 T 14-10-2018 C2I25_21625 121f2661e9fe746716d220651832910d 565 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 95 478 1.5E-76 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain C2I25_17505 bc4c99f4542599eeff0f3b4270a27d85 412 Pfam PF08662 Eukaryotic translation initiation factor eIF2A 42 154 3.0E-6 T 14-10-2018 IPR013979 Translation initiation factor, beta propellor-like domain C2I25_17505 bc4c99f4542599eeff0f3b4270a27d85 412 Gene3D G3DSA:2.120.10.30 197 399 1.1E-7 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I25_17505 bc4c99f4542599eeff0f3b4270a27d85 412 Gene3D G3DSA:2.120.10.30 23 156 3.2E-10 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I25_17505 bc4c99f4542599eeff0f3b4270a27d85 412 SUPERFAMILY SSF82171 40 389 1.44E-25 T 14-10-2018 C2I25_26545 abbd1fa3eda8d42ea0e1f4685206e992 909 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 28 345 1.1E-41 T 14-10-2018 IPR007119 Phage minor structural protein, N-terminal domain C2I25_26545 abbd1fa3eda8d42ea0e1f4685206e992 909 Pfam PF13884 Chaperone of endosialidase 774 837 6.2E-7 T 14-10-2018 IPR030392 Intramolecular chaperone auto-processing domain C2I25_26545 abbd1fa3eda8d42ea0e1f4685206e992 909 Pfam PF06605 Prophage endopeptidase tail 80 357 1.3E-23 T 14-10-2018 IPR010572 Prophage tail endopeptidase C2I25_12910 7708db518463b9f462569d27ec40ae6b 63 SUPERFAMILY SSF47413 2 61 4.02E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_12910 7708db518463b9f462569d27ec40ae6b 63 SMART SM00530 3 58 1.6E-14 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_12910 7708db518463b9f462569d27ec40ae6b 63 Pfam PF01381 Helix-turn-helix 4 56 8.9E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_12910 7708db518463b9f462569d27ec40ae6b 63 Gene3D G3DSA:1.10.260.40 1 62 1.1E-24 T 14-10-2018 C2I25_01255 86e8bd5f51a3758e62a27353eeb9756f 153 SUPERFAMILY SSF109854 1 140 2.38E-29 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_01255 86e8bd5f51a3758e62a27353eeb9756f 153 Gene3D G3DSA:1.20.120.450 1 145 1.3E-35 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_25035 32cd6fb2c9203c656a5d0ebe97eb2898 162 Gene3D G3DSA:1.20.120.450 7 140 7.0E-7 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_25035 32cd6fb2c9203c656a5d0ebe97eb2898 162 SUPERFAMILY SSF109854 9 130 4.21E-14 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_22335 e21de78e0a8a59de10160407f3f20895 162 Pfam PF05163 DinB family 7 161 4.5E-21 T 14-10-2018 IPR007837 DNA damage-inducible protein DinB C2I25_22335 e21de78e0a8a59de10160407f3f20895 162 SUPERFAMILY SSF109854 1 160 6.23E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_22335 e21de78e0a8a59de10160407f3f20895 162 Gene3D G3DSA:1.20.120.450 2 162 1.1E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_09880 c02293d1ecf64559e4eb075e6260b988 391 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 20 376 4.2E-83 T 14-10-2018 IPR010645 Uncharacterised MFS-type transporter YbfB C2I25_09880 c02293d1ecf64559e4eb075e6260b988 391 SUPERFAMILY SSF103473 4 379 1.44E-43 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_09880 c02293d1ecf64559e4eb075e6260b988 391 Gene3D G3DSA:1.20.1250.20 3 193 1.7E-20 T 14-10-2018 C2I25_09880 c02293d1ecf64559e4eb075e6260b988 391 Gene3D G3DSA:1.20.1250.20 203 382 1.3E-11 T 14-10-2018 C2I25_25515 34dfd750acd2b0beab5214c25f254933 127 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 121 2.7E-25 T 14-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like C2I25_25515 34dfd750acd2b0beab5214c25f254933 127 SUPERFAMILY SSF110857 1 125 1.19E-31 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily C2I25_25515 34dfd750acd2b0beab5214c25f254933 127 Gene3D G3DSA:3.10.490.10 2 124 8.4E-31 T 14-10-2018 C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 Gene3D G3DSA:3.20.20.80 9 107 2.9E-37 T 14-10-2018 C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 SUPERFAMILY SSF51011 472 550 2.27E-18 T 14-10-2018 C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 Gene3D G3DSA:2.60.40.1180 473 553 7.1E-24 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 Gene3D G3DSA:3.90.400.10 108 163 5.8E-28 T 14-10-2018 C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 Pfam PF16657 Maltogenic Amylase, C-terminal domain 472 545 2.4E-8 T 14-10-2018 IPR032091 Maltogenic Amylase, C-terminal C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 SUPERFAMILY SSF51445 3 469 2.38E-152 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 Pfam PF00128 Alpha amylase, catalytic domain 26 369 1.7E-124 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 4 550 1.1E-275 T 14-10-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 Gene3D G3DSA:3.20.20.80 164 472 1.2E-119 T 14-10-2018 C2I25_08330 8b0c5857b4a8225bbba10f3541a09075 553 SMART SM00642 11 411 1.4E-151 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I25_27090 4fac9a3ea00092d6cdb1873e68800653 169 Pfam PF13302 Acetyltransferase (GNAT) domain 4 138 2.6E-13 T 14-10-2018 IPR000182 GNAT domain C2I25_27090 4fac9a3ea00092d6cdb1873e68800653 169 SUPERFAMILY SSF55729 2 163 2.52E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27090 4fac9a3ea00092d6cdb1873e68800653 169 Gene3D G3DSA:3.40.630.30 1 169 9.5E-40 T 14-10-2018 C2I25_27605 a5bbe7fe1aeadb4372333e8ab1e8a12a 92 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 1.4E-10 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_27605 a5bbe7fe1aeadb4372333e8ab1e8a12a 92 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.1E-9 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_27605 a5bbe7fe1aeadb4372333e8ab1e8a12a 92 SUPERFAMILY SSF89447 1 52 4.06E-14 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I25_27605 a5bbe7fe1aeadb4372333e8ab1e8a12a 92 SMART SM00966 8 51 4.0E-8 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I25_27605 a5bbe7fe1aeadb4372333e8ab1e8a12a 92 Gene3D G3DSA:2.10.260.10 1 52 6.3E-20 T 14-10-2018 C2I25_03755 67c48c6538c7ecefe199d941cdad11f5 213 SMART SM00986 25 204 9.0E-22 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_03755 67c48c6538c7ecefe199d941cdad11f5 213 SMART SM00987 25 204 9.0E-22 T 14-10-2018 C2I25_03755 67c48c6538c7ecefe199d941cdad11f5 213 Pfam PF03167 Uracil DNA glycosylase superfamily 26 203 3.0E-41 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_03755 67c48c6538c7ecefe199d941cdad11f5 213 SUPERFAMILY SSF52141 14 209 6.54E-41 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_03755 67c48c6538c7ecefe199d941cdad11f5 213 Gene3D G3DSA:3.40.470.10 8 213 1.3E-49 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I25_23800 40d44079f74a4f1107a9cf7d2c573ea4 388 SUPERFAMILY SSF56601 51 373 1.04E-77 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_23800 40d44079f74a4f1107a9cf7d2c573ea4 388 Pfam PF00144 Beta-lactamase 63 382 4.7E-66 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_23800 40d44079f74a4f1107a9cf7d2c573ea4 388 Gene3D G3DSA:3.40.710.10 47 388 5.2E-143 T 14-10-2018 C2I25_11940 3e05a9c1a25d38115c7a17052df42690 297 SUPERFAMILY SSF51735 9 293 4.8E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_11940 3e05a9c1a25d38115c7a17052df42690 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 186 6.2E-8 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_11940 3e05a9c1a25d38115c7a17052df42690 297 Gene3D G3DSA:3.40.50.720 2 297 6.6E-32 T 14-10-2018 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 SMART SM00342 184 267 3.4E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 SUPERFAMILY SSF46689 220 272 8.06E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 Gene3D G3DSA:1.10.10.60 165 217 2.3E-10 T 14-10-2018 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 Gene3D G3DSA:1.10.10.60 218 271 3.5E-17 T 14-10-2018 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 Pfam PF12833 Helix-turn-helix domain 193 268 9.6E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 SUPERFAMILY SSF51215 15 151 1.7E-6 T 14-10-2018 IPR037923 Transcription regulator HTH-like C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 SUPERFAMILY SSF46689 167 218 7.47E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 251 6.9E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 267 6.9E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I25_23435 64a8de77f18db8ccdd42d58e02f07124 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 263 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I25_21900 7ccbe47c8e5cedd69c55e6f91f657313 363 Pfam PF13037 Domain of unknown function (DUF3898) 261 350 5.1E-43 T 14-10-2018 IPR025012 Domain of unknown function DUF3898 C2I25_21900 7ccbe47c8e5cedd69c55e6f91f657313 363 Pfam PF13039 Protein of unknown function (DUF3900) 2 254 2.9E-136 T 14-10-2018 IPR025006 Protein of unknown function DUF3900 C2I25_23770 9fe05678943efcbc192c7edbdfe032c0 73 SUPERFAMILY SSF140500 3 53 7.72E-15 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_23770 9fe05678943efcbc192c7edbdfe032c0 73 Pfam PF09388 Spo0E like sporulation regulatory protein 6 46 4.5E-15 T 14-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I25_23770 9fe05678943efcbc192c7edbdfe032c0 73 Gene3D G3DSA:1.20.58.990 1 65 5.6E-23 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_26765 efe183a4a700691ccb12bb8a07c75aea 87 Pfam PF13073 Protein of unknown function (DUF3937) 8 79 3.2E-48 T 14-10-2018 IPR025068 Protein of unknown function DUF3937 C2I25_01975 8ad5e938f418feef06557adc2f26c256 405 Gene3D G3DSA:3.40.50.2300 49 371 5.9E-113 T 14-10-2018 C2I25_01975 8ad5e938f418feef06557adc2f26c256 405 Pfam PF13458 Periplasmic binding protein 39 377 4.2E-70 T 14-10-2018 IPR028081 Leucine-binding protein domain C2I25_01975 8ad5e938f418feef06557adc2f26c256 405 SUPERFAMILY SSF53822 39 385 2.36E-80 T 14-10-2018 IPR028082 Periplasmic binding protein-like I C2I25_01975 8ad5e938f418feef06557adc2f26c256 405 Gene3D G3DSA:3.40.50.2300 161 378 5.9E-113 T 14-10-2018 C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 19 38 5.0E-6 T 14-10-2018 IPR021201 Leader peptide, exosporium C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 903 961 1.7E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 710 767 4.7E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 755 813 9.5E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 656 714 2.7E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 41 96 4.4E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 803 861 8.6E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 563 621 5.9E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 617 674 2.5E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_15615 f2bb4c68b13adff417f8b8dde13ea70f 1303 Pfam PF01391 Collagen triple helix repeat (20 copies) 957 1015 1.3E-6 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_03675 30c6d8dec4507e18e2c891383c5375bd 56 PIRSF PIRSF036698 1 56 7.2E-38 T 14-10-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA C2I25_03675 30c6d8dec4507e18e2c891383c5375bd 56 Pfam PF14084 Protein of unknown function (DUF4264) 4 56 6.3E-25 T 14-10-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA C2I25_12615 7103a7b665e3264b2675d99344f0aa4b 84 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 22 74 1.0E-14 T 14-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter C2I25_07615 885453a66c0fc64f3e0fe2acb496d835 216 SMART SM00382 28 212 1.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_07615 885453a66c0fc64f3e0fe2acb496d835 216 Pfam PF00005 ABC transporter 19 166 3.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_07615 885453a66c0fc64f3e0fe2acb496d835 216 Gene3D G3DSA:3.40.50.300 1 216 3.2E-64 T 14-10-2018 C2I25_07615 885453a66c0fc64f3e0fe2acb496d835 216 SUPERFAMILY SSF52540 1 215 2.15E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_15585 04490c28ce7bfbdc04eaf7a0a2990dd0 702 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 227 677 2.1E-143 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_25320 f09dfbf1a76aae6288823cdf1b3ce40a 308 SUPERFAMILY SSF51430 1 308 1.7E-81 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_25320 f09dfbf1a76aae6288823cdf1b3ce40a 308 Gene3D G3DSA:3.20.20.100 1 308 1.1E-91 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I25_25320 f09dfbf1a76aae6288823cdf1b3ce40a 308 Pfam PF00248 Aldo/keto reductase family 15 308 1.1E-66 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I25_21135 7f6a80289101ee21915842fbd247d5b4 121 Hamap MF_01143 Holin-like protein CidA [cidA]. 1 118 24.115 T 14-10-2018 IPR023760 Holin-like protein CidA GO:0016021 C2I25_21135 7f6a80289101ee21915842fbd247d5b4 121 Pfam PF03788 LrgA family 18 109 1.5E-30 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 C2I25_18115 b18c2cca9d644f4c5b94adcb3ba88456 167 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 24 43 2.4E-4 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I25_18115 b18c2cca9d644f4c5b94adcb3ba88456 167 Pfam PF15980 Putative Competence protein ComGF 51 153 2.9E-18 T 14-10-2018 IPR016977 Competence operon G, ComGF C2I25_18115 b18c2cca9d644f4c5b94adcb3ba88456 167 Pfam PF07963 Prokaryotic N-terminal methylation motif 23 42 3.6E-5 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I25_18085 9bd0f0b68ccb43e59fec7b8099749319 231 SUPERFAMILY SSF46785 1 204 1.12E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_18085 9bd0f0b68ccb43e59fec7b8099749319 231 Gene3D G3DSA:1.10.10.10 1 92 5.4E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_18085 9bd0f0b68ccb43e59fec7b8099749319 231 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 111 227 9.1E-6 T 14-10-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase C2I25_18085 9bd0f0b68ccb43e59fec7b8099749319 231 Pfam PF12840 Helix-turn-helix domain 7 63 5.4E-7 T 14-10-2018 C2I25_13700 e5afdc3edb14ae9bed0ac13b1ea7e38c 352 Gene3D G3DSA:3.60.10.10 50 352 5.7E-33 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_13700 e5afdc3edb14ae9bed0ac13b1ea7e38c 352 SUPERFAMILY SSF56219 43 352 2.09E-30 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I25_12975 095a4d0cbc81555fafb477609d6cb727 163 Pfam PF12773 Double zinc ribbon 106 157 4.4E-7 T 14-10-2018 IPR025874 Double zinc ribbon C2I25_17410 0a28978d06f2a907c1f85b5eeeaf5c30 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 292 3.6E-63 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I25_17410 0a28978d06f2a907c1f85b5eeeaf5c30 307 Gene3D G3DSA:3.40.50.1100 9 299 6.8E-113 T 14-10-2018 C2I25_17410 0a28978d06f2a907c1f85b5eeeaf5c30 307 SUPERFAMILY SSF53686 2 305 1.57E-90 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I25_17410 0a28978d06f2a907c1f85b5eeeaf5c30 307 Gene3D G3DSA:3.40.50.1100 45 146 6.8E-113 T 14-10-2018 C2I25_17410 0a28978d06f2a907c1f85b5eeeaf5c30 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 C2I25_27085 253bcb4d3e149161c9e444db1cf7d169 186 SUPERFAMILY SSF52540 4 163 2.08E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_27085 253bcb4d3e149161c9e444db1cf7d169 186 Gene3D G3DSA:3.40.50.300 1 180 8.1E-25 T 14-10-2018 C2I25_27085 253bcb4d3e149161c9e444db1cf7d169 186 Pfam PF13238 AAA domain 8 129 2.6E-7 T 14-10-2018 C2I25_07730 7e7de748f67782ba370656ccf7e20fe7 250 Gene3D G3DSA:1.10.3720.10 49 243 2.1E-25 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07730 7e7de748f67782ba370656ccf7e20fe7 250 SUPERFAMILY SSF161098 54 231 4.97E-29 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07730 7e7de748f67782ba370656ccf7e20fe7 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 243 1.8E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_09705 58b28d4839fcfb79420a64a7ba1c6bb6 398 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 190 397 4.6E-53 T 14-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I25_09705 58b28d4839fcfb79420a64a7ba1c6bb6 398 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 4.5E-17 T 14-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I25_19815 e6d67464a82f8ab47c9573d95b1654c7 145 Pfam PF14071 Putative coat protein 13 145 1.4E-44 T 14-10-2018 IPR025953 Putative coat protein YlbD C2I25_22140 f7e24f633899f92d7355b66454d30ddd 399 Gene3D G3DSA:3.50.50.60 123 261 6.3E-90 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_22140 f7e24f633899f92d7355b66454d30ddd 399 SUPERFAMILY SSF51905 121 261 2.47E-20 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_22140 f7e24f633899f92d7355b66454d30ddd 399 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 127 7.2E-8 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I25_22140 f7e24f633899f92d7355b66454d30ddd 399 Gene3D G3DSA:3.50.50.60 8 325 6.3E-90 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_22140 f7e24f633899f92d7355b66454d30ddd 399 SUPERFAMILY SSF51905 6 154 2.19E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_19275 57c757bd334764a5f6eee4849257c1b2 170 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 170 26.686 T 14-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 C2I25_19275 57c757bd334764a5f6eee4849257c1b2 170 Gene3D G3DSA:2.60.120.10 1 170 7.0E-61 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_19275 57c757bd334764a5f6eee4849257c1b2 170 Pfam PF03079 ARD/ARD' family 3 168 2.7E-43 T 14-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 C2I25_19275 57c757bd334764a5f6eee4849257c1b2 170 SUPERFAMILY SSF51182 9 170 6.75E-32 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_24405 c3d3ad20b3cb82b0333af85489d557d0 214 SUPERFAMILY SSF53474 10 192 1.81E-6 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_24405 c3d3ad20b3cb82b0333af85489d557d0 214 Gene3D G3DSA:3.40.50.1820 15 200 6.0E-6 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_24405 c3d3ad20b3cb82b0333af85489d557d0 214 PIRSF PIRSF033634 1 214 9.6E-74 T 14-10-2018 IPR017018 Uncharacterised conserved protein UCP033634 C2I25_05615 2823cf8cd277e8156a2605fd9cfb8fed 59 Gene3D G3DSA:1.25.40.10 1 59 3.4E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_04465 a120ab066c7eb8896973c796f769343d 447 Pfam PF02386 Cation transport protein 43 427 6.6E-50 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 C2I25_04465 a120ab066c7eb8896973c796f769343d 447 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 36 418 9.9E-113 T 14-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 C2I25_01210 627f2f1b4c9ec2a25e1cbc94c0fea228 367 Gene3D G3DSA:3.60.21.10 3 251 2.6E-41 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_01210 627f2f1b4c9ec2a25e1cbc94c0fea228 367 SUPERFAMILY SSF56300 9 200 1.25E-34 T 14-10-2018 C2I25_01210 627f2f1b4c9ec2a25e1cbc94c0fea228 367 Pfam PF00149 Calcineurin-like phosphoesterase 14 199 6.4E-13 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_27105 f9236f4fa6aee2f3fe63d8de99c3950d 646 ProSitePatterns PS00455 Putative AMP-binding domain signature. 264 275 - T 14-10-2018 IPR020845 AMP-binding, conserved site C2I25_27105 f9236f4fa6aee2f3fe63d8de99c3950d 646 Pfam PF00501 AMP-binding enzyme 100 521 2.9E-75 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I25_27105 f9236f4fa6aee2f3fe63d8de99c3950d 646 Pfam PF13193 AMP-binding enzyme C-terminal domain 530 608 5.9E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I25_27105 f9236f4fa6aee2f3fe63d8de99c3950d 646 Gene3D G3DSA:3.30.300.30 517 642 4.2E-21 T 14-10-2018 C2I25_27105 f9236f4fa6aee2f3fe63d8de99c3950d 646 Gene3D G3DSA:3.40.50.12780 59 515 1.5E-90 T 14-10-2018 C2I25_27105 f9236f4fa6aee2f3fe63d8de99c3950d 646 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 30 85 9.0E-11 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 C2I25_27105 f9236f4fa6aee2f3fe63d8de99c3950d 646 SUPERFAMILY SSF56801 17 635 2.62E-151 T 14-10-2018 C2I25_08130 64114f40c002c0134c34849116c63493 384 Pfam PF03209 PUCC protein 270 352 4.3E-6 T 14-10-2018 IPR004896 PucC-related C2I25_08130 64114f40c002c0134c34849116c63493 384 Pfam PF07690 Major Facilitator Superfamily 6 227 1.2E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_08130 64114f40c002c0134c34849116c63493 384 SUPERFAMILY SSF103473 4 377 6.93E-62 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_08130 64114f40c002c0134c34849116c63493 384 PRINTS PR01035 Tetracycline resistance protein signature 37 56 4.3E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_08130 64114f40c002c0134c34849116c63493 384 PRINTS PR01035 Tetracycline resistance protein signature 267 288 4.3E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_08130 64114f40c002c0134c34849116c63493 384 PRINTS PR01035 Tetracycline resistance protein signature 126 148 4.3E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_08130 64114f40c002c0134c34849116c63493 384 PRINTS PR01035 Tetracycline resistance protein signature 239 259 4.3E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_08130 64114f40c002c0134c34849116c63493 384 Gene3D G3DSA:1.20.1250.20 2 372 7.2E-58 T 14-10-2018 C2I25_22060 009f151fded9bf0b756af9b80225aace 367 Pfam PF03845 Spore germination protein 9 322 4.3E-58 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_22060 009f151fded9bf0b756af9b80225aace 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 356 1.8E-61 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_19395 1b006371f66796c1aa496ee681f25b9a 169 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 9.7E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19395 1b006371f66796c1aa496ee681f25b9a 169 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 9.7E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_19395 1b006371f66796c1aa496ee681f25b9a 169 SUPERFAMILY SSF51735 10 120 3.95E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_19395 1b006371f66796c1aa496ee681f25b9a 169 Gene3D G3DSA:3.40.50.720 8 127 2.8E-26 T 14-10-2018 C2I25_19395 1b006371f66796c1aa496ee681f25b9a 169 Pfam PF00106 short chain dehydrogenase 17 116 2.1E-21 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_02245 167bce45020c55128025712eb18f8d77 207 SUPERFAMILY SSF55729 37 200 2.53E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_02245 167bce45020c55128025712eb18f8d77 207 Gene3D G3DSA:3.40.630.30 16 207 3.5E-34 T 14-10-2018 C2I25_02245 167bce45020c55128025712eb18f8d77 207 Pfam PF00583 Acetyltransferase (GNAT) family 42 181 4.4E-13 T 14-10-2018 IPR000182 GNAT domain C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 162 1.6E-35 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 Pfam PF00425 chorismate binding enzyme 213 466 1.2E-99 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 SUPERFAMILY SSF56322 20 474 1.57E-157 T 14-10-2018 IPR005801 ADC synthase GO:0009058 C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 Gene3D G3DSA:3.60.120.10 1 475 4.1E-170 T 14-10-2018 IPR005801 ADC synthase GO:0009058 C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 29 474 1.6E-178 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 PRINTS PR00095 Anthranilate synthase component I signature 408 422 8.6E-24 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 PRINTS PR00095 Anthranilate synthase component I signature 314 327 8.6E-24 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 PRINTS PR00095 Anthranilate synthase component I signature 328 341 8.6E-24 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_05225 36fbd5bea2afd36b276f478fcd12d7d5 475 PRINTS PR00095 Anthranilate synthase component I signature 423 437 8.6E-24 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I25_03455 aab08df75d8fdf65d91e0ab891aba0d3 188 Gene3D G3DSA:3.40.50.300 1 188 2.9E-23 T 14-10-2018 C2I25_03455 aab08df75d8fdf65d91e0ab891aba0d3 188 SUPERFAMILY SSF52540 34 186 3.14E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02885 f3a63e12cffe53de50edb735b1a9f18f 363 SUPERFAMILY SSF56601 39 334 1.16E-27 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_02885 f3a63e12cffe53de50edb735b1a9f18f 363 Gene3D G3DSA:3.40.710.10 34 346 1.4E-39 T 14-10-2018 C2I25_02885 f3a63e12cffe53de50edb735b1a9f18f 363 Pfam PF13354 Beta-lactamase enzyme family 57 279 2.0E-16 T 14-10-2018 C2I25_28190 94bde3af4bf38107edd1414fff4927bb 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 57 1.0E-23 T 14-10-2018 IPR018690 Protein of unknown function DUF2187 C2I25_01930 ed2162aed4a27b94935c104a8a13e1e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 1.1E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01930 ed2162aed4a27b94935c104a8a13e1e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.1E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01930 ed2162aed4a27b94935c104a8a13e1e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.1E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01930 ed2162aed4a27b94935c104a8a13e1e7 147 Gene3D G3DSA:1.10.10.10 3 143 2.4E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01930 ed2162aed4a27b94935c104a8a13e1e7 147 SMART SM00347 27 124 2.5E-21 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01930 ed2162aed4a27b94935c104a8a13e1e7 147 SUPERFAMILY SSF46785 9 138 2.66E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01930 ed2162aed4a27b94935c104a8a13e1e7 147 Pfam PF01047 MarR family 34 85 3.2E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_02935 ccb6d78ae029f60620f077fa2451262a 174 SUPERFAMILY SSF48452 20 95 6.42E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_02935 ccb6d78ae029f60620f077fa2451262a 174 Pfam PF14346 Domain of unknown function (DUF4398) 12 119 2.2E-16 T 14-10-2018 IPR025511 Domain of unknown function DUF4398 C2I25_07270 fdcf34fd60572281f8de061152787fc4 122 Pfam PF13157 Protein of unknown function (DUF3992) 23 117 2.3E-36 T 14-10-2018 IPR025055 Protein of unknown function DUF3992 C2I25_28255 a264dfafee2003f1d20bdc65e8b8b2d4 478 SUPERFAMILY SSF103378 11 476 3.4E-160 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 C2I25_28255 a264dfafee2003f1d20bdc65e8b8b2d4 478 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 11 478 1.4E-283 T 14-10-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 C2I25_28255 a264dfafee2003f1d20bdc65e8b8b2d4 478 Gene3D G3DSA:3.30.1330.120 283 421 2.9E-194 T 14-10-2018 C2I25_28255 a264dfafee2003f1d20bdc65e8b8b2d4 478 Gene3D G3DSA:1.10.4100.10 20 456 2.9E-194 T 14-10-2018 C2I25_28255 a264dfafee2003f1d20bdc65e8b8b2d4 478 Pfam PF03972 MmgE/PrpD family 15 461 9.9E-153 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 C2I25_01465 72c6d0c60b15122fad9de3720cebda08 138 Gene3D G3DSA:3.10.180.10 1 135 1.2E-38 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_01465 72c6d0c60b15122fad9de3720cebda08 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 5.2E-12 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_01465 72c6d0c60b15122fad9de3720cebda08 138 SUPERFAMILY SSF54593 3 129 3.09E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_01465 72c6d0c60b15122fad9de3720cebda08 138 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 1 138 42.825 T 14-10-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 C2I25_03725 e794ec564cfe6521aedc17339db6500a 234 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 4 224 4.7E-99 T 14-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 C2I25_03725 e794ec564cfe6521aedc17339db6500a 234 SUPERFAMILY SSF102588 4 226 4.45E-59 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I25_03725 e794ec564cfe6521aedc17339db6500a 234 Gene3D G3DSA:3.40.50.10320 1 234 5.0E-101 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I25_03725 e794ec564cfe6521aedc17339db6500a 234 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 124 1.5E-23 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 C2I25_27425 3d125f3b1500f858644b2c697cdd0739 210 Gene3D G3DSA:3.40.50.1110 9 204 3.3E-32 T 14-10-2018 IPR036514 SGNH hydrolase superfamily C2I25_27425 3d125f3b1500f858644b2c697cdd0739 210 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 21 193 6.5E-24 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain C2I25_27425 3d125f3b1500f858644b2c697cdd0739 210 SUPERFAMILY SSF52266 16 204 8.86E-35 T 14-10-2018 C2I25_01010 d01ae6b68db770c026b08af1614d297f 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 7.7E-22 T 14-10-2018 C2I25_01010 d01ae6b68db770c026b08af1614d297f 77 Pfam PF02597 ThiS family 4 77 1.2E-14 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 C2I25_01010 d01ae6b68db770c026b08af1614d297f 77 Gene3D G3DSA:3.10.20.30 1 77 3.6E-19 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_01010 d01ae6b68db770c026b08af1614d297f 77 SUPERFAMILY SSF54285 1 77 7.85E-17 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp C2I25_03580 3ea06426f06f4e785dd0b62f6c498ead 60 Pfam PF13060 Protein of unknown function (DUF3921) 1 58 3.3E-41 T 14-10-2018 IPR025036 Protein of unknown function DUF3921 C2I25_13075 38f031a6c7ee52b0d7118061db87206b 553 Pfam PF02652 L-lactate permease 17 543 1.1E-214 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I25_13075 38f031a6c7ee52b0d7118061db87206b 553 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 546 1.1E-224 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I25_02515 b76e9b712fbc68a336f2a866e65a34bd 424 Gene3D G3DSA:1.20.1250.20 18 419 7.9E-41 T 14-10-2018 C2I25_02515 b76e9b712fbc68a336f2a866e65a34bd 424 SUPERFAMILY SSF103473 19 421 6.93E-49 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_02515 b76e9b712fbc68a336f2a866e65a34bd 424 Pfam PF07690 Major Facilitator Superfamily 44 285 6.3E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_21540 49f377a22e7e1c1171195eff6146ca61 618 SUPERFAMILY SSF51998 30 596 5.04E-161 T 14-10-2018 C2I25_21540 49f377a22e7e1c1171195eff6146ca61 618 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 29 617 2.5E-208 T 14-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 C2I25_21540 49f377a22e7e1c1171195eff6146ca61 618 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 28 617 9.8E-221 T 14-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 C2I25_21540 49f377a22e7e1c1171195eff6146ca61 618 Gene3D G3DSA:3.20.70.20 42 599 6.0E-205 T 14-10-2018 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 39.321 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 Gene3D G3DSA:1.20.120.640 306 464 3.8E-34 T 14-10-2018 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 SUPERFAMILY SSF52374 4 314 1.45E-104 T 14-10-2018 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 Gene3D G3DSA:3.40.50.620 1 305 2.4E-137 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 1.8E-137 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 464 1.3E-189 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.2E-29 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.2E-29 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.2E-29 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.2E-29 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 Pfam PF09190 DALR domain 353 413 1.6E-14 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 SUPERFAMILY SSF47323 317 464 1.14E-34 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I25_11080 ef61cfab9b8ff9d374ecb329a2257957 467 SMART SM00840 353 416 1.3E-14 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 C2I25_23495 b0144b5d9cd4aa929a47ab8a3e6c3c56 270 Gene3D G3DSA:3.90.70.10 74 270 3.6E-68 T 14-10-2018 C2I25_23495 b0144b5d9cd4aa929a47ab8a3e6c3c56 270 Pfam PF13529 Peptidase_C39 like family 79 240 8.4E-32 T 14-10-2018 IPR039564 Peptidase C39-like C2I25_23495 b0144b5d9cd4aa929a47ab8a3e6c3c56 270 PIRSF PIRSF032442 1 270 1.4E-77 T 14-10-2018 IPR016997 Uncharacterised conserved protein UCP032442 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 Gene3D G3DSA:2.40.50.530 1 63 5.2E-22 T 14-10-2018 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 5.1E-26 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 4.6E-21 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 4.6E-21 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 4.6E-21 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 SUPERFAMILY SSF143034 2 62 3.53E-22 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.829 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I25_16440 f2c6294f06ff53f6066df6d707107931 66 Pfam PF01632 Ribosomal protein L35 2 62 2.5E-25 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_05370 e1cb88c9ab0274b2bd32ab817f57b57a 386 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 338 362 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_05370 e1cb88c9ab0274b2bd32ab817f57b57a 386 Pfam PF01098 Cell cycle protein 14 381 1.6E-88 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_24700 077507a835f22e7a891750c9471bfff9 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 313 3.7E-46 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I25_25850 7b685434c2170dd2d6e65e22a1aa2cb1 165 Pfam PF00583 Acetyltransferase (GNAT) family 36 142 3.4E-9 T 14-10-2018 IPR000182 GNAT domain C2I25_25850 7b685434c2170dd2d6e65e22a1aa2cb1 165 SUPERFAMILY SSF55729 8 151 2.42E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25850 7b685434c2170dd2d6e65e22a1aa2cb1 165 Gene3D G3DSA:3.40.630.30 9 150 4.2E-15 T 14-10-2018 C2I25_23105 2d47a9f5d6d43c7a95ca85787a119f6e 153 Gene3D G3DSA:3.90.79.10 1 148 1.1E-35 T 14-10-2018 C2I25_23105 2d47a9f5d6d43c7a95ca85787a119f6e 153 Pfam PF00293 NUDIX domain 23 142 6.3E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_23105 2d47a9f5d6d43c7a95ca85787a119f6e 153 SUPERFAMILY SSF55811 1 147 9.61E-33 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_23105 2d47a9f5d6d43c7a95ca85787a119f6e 153 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_23105 2d47a9f5d6d43c7a95ca85787a119f6e 153 PRINTS PR00502 NUDIX hydrolase family signature 57 72 2.7E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_23105 2d47a9f5d6d43c7a95ca85787a119f6e 153 PRINTS PR00502 NUDIX hydrolase family signature 43 57 2.7E-5 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 SMART SM00843 723 788 6.0E-40 T 14-10-2018 IPR018541 FtsK gamma domain C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 Pfam PF01580 FtsK/SpoIIIE family 432 628 2.5E-65 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 Gene3D G3DSA:1.10.10.10 720 784 5.7E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 SMART SM00382 467 649 0.0016 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 SUPERFAMILY SSF52540 405 700 1.95E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 Gene3D G3DSA:3.40.50.300 429 714 3.1E-111 T 14-10-2018 C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 Pfam PF09397 Ftsk gamma domain 726 785 2.5E-30 T 14-10-2018 IPR018541 FtsK gamma domain C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 Gene3D G3DSA:3.30.980.40 324 427 2.4E-38 T 14-10-2018 C2I25_20540 fa4d73614d39fe9c3f11a46b7cbdb40e 793 SUPERFAMILY SSF46785 724 786 5.98E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_07700 f22da2322f719d485a3beacc8dbd5bc9 339 Pfam PF00899 ThiF family 5 241 1.8E-60 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I25_07700 f22da2322f719d485a3beacc8dbd5bc9 339 SUPERFAMILY SSF69572 2 330 2.22E-88 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I25_07700 f22da2322f719d485a3beacc8dbd5bc9 339 TIGRFAM TIGR02356 adenyl_thiF: thiazole biosynthesis adenylyltransferase ThiF 4 206 9.8E-84 T 14-10-2018 IPR012731 Thiazole biosynthesis adenylyltransferase ThiF KEGG: 00730+2.7.7.73|MetaCyc: PWY-6891|MetaCyc: PWY-6892 C2I25_07700 f22da2322f719d485a3beacc8dbd5bc9 339 Gene3D G3DSA:3.40.50.720 2 250 7.4E-76 T 14-10-2018 C2I25_22645 8a5093ac2d5c67daaef4a16c6b0008a8 141 Pfam PF07291 Methylamine utilisation protein MauE 9 124 6.3E-5 T 14-10-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 C2I25_28060 4f4253bad516367b11ef5b84ba8b953f 286 Gene3D G3DSA:1.10.3720.10 58 286 2.6E-6 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_28060 4f4253bad516367b11ef5b84ba8b953f 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 280 5.1E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_28060 4f4253bad516367b11ef5b84ba8b953f 286 SUPERFAMILY SSF161098 70 265 4.36E-6 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07040 153bc680fa79913a484a15ca726435b9 485 Gene3D G3DSA:3.30.470.20 311 436 6.3E-7 T 14-10-2018 C2I25_07040 153bc680fa79913a484a15ca726435b9 485 SUPERFAMILY SSF56059 212 419 6.62E-12 T 14-10-2018 C2I25_07040 153bc680fa79913a484a15ca726435b9 485 Pfam PF14398 YheC/D like ATP-grasp 188 442 1.1E-83 T 14-10-2018 IPR026838 Endospore coat-associated protein YheC/D C2I25_06115 3143b2d691be42ba4628a84b76083ced 483 PIRSF PIRSF026631 1 483 7.4E-144 T 14-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 C2I25_06115 3143b2d691be42ba4628a84b76083ced 483 Pfam PF03703 Bacterial PH domain 401 476 1.7E-10 T 14-10-2018 IPR005182 Domain of unknown function DUF304 C2I25_06115 3143b2d691be42ba4628a84b76083ced 483 Pfam PF03703 Bacterial PH domain 252 332 2.8E-10 T 14-10-2018 IPR005182 Domain of unknown function DUF304 C2I25_06115 3143b2d691be42ba4628a84b76083ced 483 Pfam PF03703 Bacterial PH domain 55 134 3.4E-16 T 14-10-2018 IPR005182 Domain of unknown function DUF304 C2I25_12765 3803705f3a28d8eba755c413e524e332 234 Pfam PF12698 ABC-2 family transporter protein 49 222 2.2E-10 T 14-10-2018 C2I25_08640 45f4f820a6fbad9d767c7c4646a57782 458 Gene3D G3DSA:3.40.190.10 52 404 2.1E-125 T 14-10-2018 C2I25_08640 45f4f820a6fbad9d767c7c4646a57782 458 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 159 176 - T 14-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 C2I25_08640 45f4f820a6fbad9d767c7c4646a57782 458 Gene3D G3DSA:3.40.190.10 164 443 2.1E-125 T 14-10-2018 C2I25_08640 45f4f820a6fbad9d767c7c4646a57782 458 SUPERFAMILY SSF53850 50 445 1.13E-83 T 14-10-2018 C2I25_08640 45f4f820a6fbad9d767c7c4646a57782 458 Pfam PF13416 Bacterial extracellular solute-binding protein 67 383 3.2E-53 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I25_12045 5a521f7427af8950ab3ee4875fe58c70 170 SUPERFAMILY SSF54637 1 150 9.48E-43 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_12045 5a521f7427af8950ab3ee4875fe58c70 170 Gene3D G3DSA:3.10.129.10 1 164 1.3E-52 T 14-10-2018 C2I25_12045 5a521f7427af8950ab3ee4875fe58c70 170 Pfam PF03061 Thioesterase superfamily 25 97 3.0E-14 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I25_05300 b8ed0c3ca470aaf09fc3f78084a3dbb5 180 Pfam PF14153 Spore coat protein CotO 6 180 1.1E-54 T 14-10-2018 IPR025439 Spore coat protein CotO C2I25_01720 737b2dcebf765e3e9eed4fe327f76c44 180 Gene3D G3DSA:3.40.630.30 4 169 4.2E-32 T 14-10-2018 C2I25_01720 737b2dcebf765e3e9eed4fe327f76c44 180 SUPERFAMILY SSF55729 1 145 4.33E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01720 737b2dcebf765e3e9eed4fe327f76c44 180 Pfam PF00583 Acetyltransferase (GNAT) family 44 144 1.6E-9 T 14-10-2018 IPR000182 GNAT domain C2I25_24005 5686c32502cb284098acb0d2fad23b67 91 SUPERFAMILY SSF53474 5 85 3.63E-7 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_24005 5686c32502cb284098acb0d2fad23b67 91 Gene3D G3DSA:3.40.50.1820 2 83 9.8E-8 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 Pfam PF01202 Shikimate kinase 10 163 2.3E-48 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 PRINTS PR01100 Shikimate kinase family signature 4 19 1.5E-21 T 14-10-2018 C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 PRINTS PR01100 Shikimate kinase family signature 28 41 1.5E-21 T 14-10-2018 C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 PRINTS PR01100 Shikimate kinase family signature 94 111 1.5E-21 T 14-10-2018 C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 PRINTS PR01100 Shikimate kinase family signature 56 64 1.5E-21 T 14-10-2018 C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 PRINTS PR01100 Shikimate kinase family signature 73 82 1.5E-21 T 14-10-2018 C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 SUPERFAMILY SSF52540 3 160 5.95E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 Gene3D G3DSA:3.40.50.300 1 165 1.1E-51 T 14-10-2018 C2I25_18130 303f7cd7bfe5290da0f558394c8991e7 165 Hamap MF_00109 Shikimate kinase [aroK]. 1 164 25.632 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 C2I25_24650 7bf83440e2b8e4677a4b1fb6963f44e2 404 Gene3D G3DSA:1.20.1250.20 3 388 1.1E-39 T 14-10-2018 C2I25_24650 7bf83440e2b8e4677a4b1fb6963f44e2 404 SUPERFAMILY SSF103473 6 390 3.01E-47 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_24650 7bf83440e2b8e4677a4b1fb6963f44e2 404 Pfam PF07690 Major Facilitator Superfamily 31 355 7.3E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_18220 95a5175be4b59fed4871973b13ab1c05 197 Pfam PF13346 ABC-2 family transporter protein 3 193 1.5E-31 T 14-10-2018 IPR025699 ABC-2 membrane transporter-like C2I25_19510 542427961ec851f4a48c214b2da5d5ac 512 Gene3D G3DSA:3.30.420.40 2 112 1.5E-23 T 14-10-2018 C2I25_19510 542427961ec851f4a48c214b2da5d5ac 512 SUPERFAMILY SSF53067 132 307 7.58E-40 T 14-10-2018 C2I25_19510 542427961ec851f4a48c214b2da5d5ac 512 Gene3D G3DSA:1.10.3210.10 338 509 4.5E-25 T 14-10-2018 C2I25_19510 542427961ec851f4a48c214b2da5d5ac 512 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 9 305 1.6E-92 T 14-10-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 C2I25_19510 542427961ec851f4a48c214b2da5d5ac 512 SUPERFAMILY SSF109604 316 508 1.16E-22 T 14-10-2018 C2I25_19510 542427961ec851f4a48c214b2da5d5ac 512 Gene3D G3DSA:3.30.420.150 113 303 5.2E-53 T 14-10-2018 C2I25_19510 542427961ec851f4a48c214b2da5d5ac 512 SUPERFAMILY SSF53067 9 129 3.32E-28 T 14-10-2018 C2I25_19510 542427961ec851f4a48c214b2da5d5ac 512 Pfam PF02541 Ppx/GppA phosphatase family 22 307 3.4E-49 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 C2I25_17600 4906887f79b58d5ca5a05b9344d3c0d0 368 Gene3D G3DSA:3.40.50.300 56 225 4.5E-53 T 14-10-2018 C2I25_17600 4906887f79b58d5ca5a05b9344d3c0d0 368 Pfam PF01926 50S ribosome-binding GTPase 163 237 1.1E-13 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 C2I25_17600 4906887f79b58d5ca5a05b9344d3c0d0 368 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 368 3.3E-157 T 14-10-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH C2I25_17600 4906887f79b58d5ca5a05b9344d3c0d0 368 SUPERFAMILY SSF52540 68 281 2.55E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_20765 6e9b1195fc7eaad2738ee3362c7fe00b 327 Gene3D G3DSA:3.40.50.720 3 305 5.1E-120 T 14-10-2018 C2I25_20765 6e9b1195fc7eaad2738ee3362c7fe00b 327 SUPERFAMILY SSF51735 1 257 4.29E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_20765 6e9b1195fc7eaad2738ee3362c7fe00b 327 Gene3D G3DSA:3.90.25.30 164 316 5.1E-120 T 14-10-2018 C2I25_20765 6e9b1195fc7eaad2738ee3362c7fe00b 327 Pfam PF02719 Polysaccharide biosynthesis protein 6 278 7.8E-104 T 14-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain C2I25_18030 6157416ba61adb6f3c73ded7bff30d82 376 Pfam PF07282 Putative transposase DNA-binding domain 300 372 8.5E-19 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal C2I25_18030 6157416ba61adb6f3c73ded7bff30d82 376 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 251 324 2.1E-8 T 14-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal C2I25_18030 6157416ba61adb6f3c73ded7bff30d82 376 Pfam PF01385 Probable transposase 170 283 5.6E-14 T 14-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 C2I25_18030 6157416ba61adb6f3c73ded7bff30d82 376 Pfam PF12323 Helix-turn-helix domain 1 45 1.1E-11 T 14-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain C2I25_13190 803ca60934f3730af729a0d210e15e6f 107 Gene3D G3DSA:1.20.58.280 1 106 1.5E-44 T 14-10-2018 C2I25_13190 803ca60934f3730af729a0d210e15e6f 107 SUPERFAMILY SSF46973 1 101 1.07E-37 T 14-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 C2I25_13190 803ca60934f3730af729a0d210e15e6f 107 PIRSF PIRSF000699 1 107 1.7E-41 T 14-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I25_13190 803ca60934f3730af729a0d210e15e6f 107 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 100 3.5E-37 T 14-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I25_01415 4d83ccf3c823db9f1468b294f27f6c76 289 Pfam PF09323 Domain of unknown function (DUF1980) 1 193 4.3E-65 T 14-10-2018 IPR015402 Protein of unknown function DUF1980 C2I25_01415 4d83ccf3c823db9f1468b294f27f6c76 289 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 283 3.2E-68 T 14-10-2018 IPR015402 Protein of unknown function DUF1980 C2I25_04225 00ad077ce5a7eb15446d75ae3de92819 220 Pfam PF04012 PspA/IM30 family 5 208 1.7E-28 T 14-10-2018 IPR007157 PspA/IM30 C2I25_13135 7d9726c91f32bea5eddf95d296579494 666 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 454 657 6.9E-61 T 14-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal C2I25_13135 7d9726c91f32bea5eddf95d296579494 666 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 1.3E-66 T 14-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal C2I25_13135 7d9726c91f32bea5eddf95d296579494 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 261 286 1.2E-5 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_13135 7d9726c91f32bea5eddf95d296579494 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 415 440 1.5E-4 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_13135 7d9726c91f32bea5eddf95d296579494 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 203 229 1.6E-6 T 14-10-2018 IPR023908 xxxLxxG heptad repeat C2I25_13135 7d9726c91f32bea5eddf95d296579494 666 Pfam PF12698 ABC-2 family transporter protein 24 165 1.2E-12 T 14-10-2018 C2I25_13135 7d9726c91f32bea5eddf95d296579494 666 SUPERFAMILY SSF101967 176 287 6.02E-5 T 14-10-2018 C2I25_06600 6c197b84145fe8fbaf4635f4945138aa 88 Pfam PF14157 YmzC-like protein 28 87 3.8E-28 T 14-10-2018 IPR025448 YmzC-like protein C2I25_01065 066dd4f40d518bc84488618237db877e 404 Pfam PF01882 Protein of unknown function DUF58 206 277 2.9E-19 T 14-10-2018 IPR002881 Domain of unknown function DUF58 C2I25_18380 3b43d5a161adb70ba43147fc1bbb995f 220 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 33 220 3.2E-72 T 14-10-2018 IPR014195 Sporulation stage III, protein AG C2I25_27320 02616270c7945744e8cc371f7738db3b 76 Gene3D G3DSA:1.10.8.910 14 75 2.8E-17 T 14-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I25_27320 02616270c7945744e8cc371f7738db3b 76 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 14 69 4.4E-13 T 14-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I25_15365 47436d8db675141de1732832a1811881 241 Pfam PF13731 WxL domain surface cell wall-binding 31 240 8.3E-62 T 14-10-2018 IPR027994 WxL domain C2I25_28075 9106745d893188fd06e84f4893d6dfb2 255 SMART SM00382 35 223 8.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_28075 9106745d893188fd06e84f4893d6dfb2 255 Gene3D G3DSA:3.40.50.300 3 252 5.8E-67 T 14-10-2018 C2I25_28075 9106745d893188fd06e84f4893d6dfb2 255 SUPERFAMILY SSF52540 6 232 8.87E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_28075 9106745d893188fd06e84f4893d6dfb2 255 Pfam PF00005 ABC transporter 26 174 1.2E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_16945 e0d969d828ce577c5da2d1bdb0d62acc 150 SMART SM00347 29 127 3.9E-19 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_16945 e0d969d828ce577c5da2d1bdb0d62acc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.7E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_16945 e0d969d828ce577c5da2d1bdb0d62acc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.7E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_16945 e0d969d828ce577c5da2d1bdb0d62acc 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.7E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_16945 e0d969d828ce577c5da2d1bdb0d62acc 150 Gene3D G3DSA:1.10.10.10 2 144 1.8E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_16945 e0d969d828ce577c5da2d1bdb0d62acc 150 SUPERFAMILY SSF46785 4 143 1.52E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_16945 e0d969d828ce577c5da2d1bdb0d62acc 150 Pfam PF01047 MarR family 36 94 2.5E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04860 975b67398471a8d3a5eab1d49aa616a4 147 SUPERFAMILY SSF54637 15 144 7.9E-40 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_04860 975b67398471a8d3a5eab1d49aa616a4 147 Pfam PF01575 MaoC like domain 25 127 1.7E-25 T 14-10-2018 IPR002539 MaoC-like dehydratase domain C2I25_04860 975b67398471a8d3a5eab1d49aa616a4 147 Gene3D G3DSA:3.10.129.10 5 147 3.2E-46 T 14-10-2018 C2I25_21320 b4e744f4a2a1ba43c9d07a5a1d63d9a2 67 Gene3D G3DSA:2.20.25.10 6 52 1.4E-5 T 14-10-2018 C2I25_27215 c5ff3782889195da3a9d21d622d93a67 351 SUPERFAMILY SSF50969 13 331 8.63E-33 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like C2I25_27215 c5ff3782889195da3a9d21d622d93a67 351 Gene3D G3DSA:2.130.10.10 263 347 1.9E-9 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_27215 c5ff3782889195da3a9d21d622d93a67 351 Gene3D G3DSA:2.130.10.10 2 253 5.8E-30 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_14320 06182bda9a0845046bf21f35157dac4b 370 PIRSF PIRSF020979 1 363 7.4E-92 T 14-10-2018 IPR011215 Phosphoribosyl transferase C2I25_14320 06182bda9a0845046bf21f35157dac4b 370 Pfam PF11202 Phosphoribosyl transferase (PRTase) 9 257 2.8E-110 T 14-10-2018 IPR011215 Phosphoribosyl transferase C2I25_14320 06182bda9a0845046bf21f35157dac4b 370 Pfam PF15608 PELOTA RNA binding domain 284 364 5.6E-36 T 14-10-2018 IPR028157 PELOTA RNA-binding domain C2I25_15650 39fc23030b00fd33a147bf041ac697a4 154 SUPERFAMILY SSF54690 4 138 1.01E-46 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_15650 39fc23030b00fd33a147bf041ac697a4 154 Pfam PF02391 MoaE protein 10 119 1.5E-35 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_15650 39fc23030b00fd33a147bf041ac697a4 154 Gene3D G3DSA:3.90.1170.40 3 145 9.7E-53 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I25_12695 39957167f6e36376c09fcb76f545fa23 366 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 3 366 47.008 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12695 39957167f6e36376c09fcb76f545fa23 366 SUPERFAMILY SSF56762 16 365 1.44E-118 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12695 39957167f6e36376c09fcb76f545fa23 366 Gene3D G3DSA:1.10.645.20 4 366 9.2E-152 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12695 39957167f6e36376c09fcb76f545fa23 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 291 365 2.9E-25 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12695 39957167f6e36376c09fcb76f545fa23 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 291 1.5E-68 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_19035 ce14c503ec36cc81bedb1bb89c3b864d 429 Pfam PF00860 Permease family 20 387 2.2E-32 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I25_19490 c4542fb8511636b7d12c16dfbd9ad103 77 Pfam PF04688 SPP1 phage holin 2 74 2.1E-18 T 14-10-2018 IPR006479 Holin C2I25_04565 0020a6b5eb01eea81ddc512fd6c59521 388 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 121 345 1.9E-14 T 14-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT C2I25_04565 0020a6b5eb01eea81ddc512fd6c59521 388 PIRSF PIRSF016636 2 385 2.6E-79 T 14-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB C2I25_04565 0020a6b5eb01eea81ddc512fd6c59521 388 PIRSF PIRSF500216 1 388 2.0E-159 T 14-10-2018 IPR024024 D-alanyl transfer protein DltB C2I25_04565 0020a6b5eb01eea81ddc512fd6c59521 388 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 3 384 3.6E-155 T 14-10-2018 IPR024024 D-alanyl transfer protein DltB C2I25_02915 3e2e68c707ecb19c6516d067970b8287 556 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 368 552 3.0E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_02915 3e2e68c707ecb19c6516d067970b8287 556 SUPERFAMILY SSF161098 294 551 2.52E-41 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_02915 3e2e68c707ecb19c6516d067970b8287 556 Gene3D G3DSA:1.10.3720.10 11 275 2.2E-44 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_02915 3e2e68c707ecb19c6516d067970b8287 556 Gene3D G3DSA:1.10.3720.10 291 554 6.3E-39 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_02915 3e2e68c707ecb19c6516d067970b8287 556 SUPERFAMILY SSF161098 11 271 8.13E-39 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_22465 14f5561674ad8d43fc02c7727070cb19 117 SUPERFAMILY SSF54593 4 115 4.93E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_22465 14f5561674ad8d43fc02c7727070cb19 117 Gene3D G3DSA:3.10.180.10 1 116 8.6E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_03920 283b2bf6067f307315c61f7e60c8f5b7 57 Pfam PF17313 Family of unknown function (DUF5359) 1 56 2.3E-23 T 14-10-2018 IPR035281 Protein of unknown function DUF5359 C2I25_21590 22bf85bd780d2c6b89741cd56584a87f 322 Pfam PF13280 WYL domain 147 310 1.8E-14 T 14-10-2018 IPR026881 WYL domain C2I25_21590 22bf85bd780d2c6b89741cd56584a87f 322 Gene3D G3DSA:1.10.10.10 4 70 3.7E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_21590 22bf85bd780d2c6b89741cd56584a87f 322 Pfam PF08279 HTH domain 14 66 1.3E-9 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 C2I25_21590 22bf85bd780d2c6b89741cd56584a87f 322 SUPERFAMILY SSF46785 9 68 3.63E-6 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_21590 22bf85bd780d2c6b89741cd56584a87f 322 SMART SM00420 14 67 0.0056 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I25_27380 925f4a2422e510ec34413edd5a0f89ed 474 PRINTS PR00175 Sodium/alanine symporter signature 181 199 4.1E-51 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_27380 925f4a2422e510ec34413edd5a0f89ed 474 PRINTS PR00175 Sodium/alanine symporter signature 345 367 4.1E-51 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_27380 925f4a2422e510ec34413edd5a0f89ed 474 PRINTS PR00175 Sodium/alanine symporter signature 405 425 4.1E-51 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_27380 925f4a2422e510ec34413edd5a0f89ed 474 PRINTS PR00175 Sodium/alanine symporter signature 91 113 4.1E-51 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_27380 925f4a2422e510ec34413edd5a0f89ed 474 PRINTS PR00175 Sodium/alanine symporter signature 300 318 4.1E-51 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_27380 925f4a2422e510ec34413edd5a0f89ed 474 PRINTS PR00175 Sodium/alanine symporter signature 209 228 4.1E-51 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_27380 925f4a2422e510ec34413edd5a0f89ed 474 Pfam PF01235 Sodium:alanine symporter family 52 448 5.7E-156 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_27380 925f4a2422e510ec34413edd5a0f89ed 474 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 436 1.2E-149 T 14-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I25_02195 60c40f47a59a3fc180bbad4d81f7f1c1 159 PIRSF PIRSF021441 1 158 1.7E-68 T 14-10-2018 IPR031306 CcdC protein C2I25_02195 60c40f47a59a3fc180bbad4d81f7f1c1 159 Pfam PF07301 Protein of unknown function (DUF1453) 5 148 4.3E-58 T 14-10-2018 IPR009916 Protein of unknown function DUF1453 C2I25_01360 3e38af6c3a884a3144621bc831adb6a2 214 Pfam PF13787 Protein of unknown function with HXXEE motif 44 154 3.6E-15 T 14-10-2018 IPR025671 Protein of unknown function with HXXEE motif C2I25_17805 a1aa45fac0c7195c0647144c1f39e154 270 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 266 60.707 T 14-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein C2I25_17805 a1aa45fac0c7195c0647144c1f39e154 270 Pfam PF03618 Kinase/pyrophosphorylase 6 260 8.4E-96 T 14-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 C2I25_22580 f0ab5f882947aa830e59efdbba9ed753 240 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 18 233 5.8E-97 T 14-10-2018 IPR014244 RNA polymerase sigma-I type C2I25_22580 f0ab5f882947aa830e59efdbba9ed753 240 Pfam PF04542 Sigma-70 region 2 32 101 1.3E-8 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_22580 f0ab5f882947aa830e59efdbba9ed753 240 Gene3D G3DSA:1.10.1740.10 17 98 1.5E-10 T 14-10-2018 C2I25_22580 f0ab5f882947aa830e59efdbba9ed753 240 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 13 235 28.278 T 14-10-2018 IPR014244 RNA polymerase sigma-I type C2I25_22580 f0ab5f882947aa830e59efdbba9ed753 240 SUPERFAMILY SSF88946 20 100 5.49E-17 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I25_22580 f0ab5f882947aa830e59efdbba9ed753 240 PIRSF PIRSF038953 6 240 2.3E-59 T 14-10-2018 IPR014244 RNA polymerase sigma-I type C2I25_14140 8c67a58ca5b30ea564013420b49ae10f 127 SUPERFAMILY SSF51230 3 125 2.36E-46 T 14-10-2018 IPR011053 Single hybrid motif C2I25_14140 8c67a58ca5b30ea564013420b49ae10f 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 9.7E-58 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 C2I25_14140 8c67a58ca5b30ea564013420b49ae10f 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 C2I25_14140 8c67a58ca5b30ea564013420b49ae10f 127 Gene3D G3DSA:2.40.50.100 1 124 9.4E-53 T 14-10-2018 C2I25_14140 8c67a58ca5b30ea564013420b49ae10f 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.698 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 C2I25_14140 8c67a58ca5b30ea564013420b49ae10f 127 Pfam PF01597 Glycine cleavage H-protein 7 126 2.1E-49 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate C2I25_18190 15a359610edc19108adb10b0c1770a43 74 Pfam PF13066 Protein of unknown function (DUF3929) 8 71 1.2E-47 T 14-10-2018 IPR025171 Protein of unknown function DUF3929 C2I25_01445 806d211dba80bb033feaac1f22384509 358 Pfam PF08757 CotH kinase protein 43 350 1.2E-85 T 14-10-2018 IPR014867 Spore coat protein CotH C2I25_09215 9d55338da78dd6df9e3c20624d770381 142 Pfam PF00892 EamA-like transporter family 3 140 7.0E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_09215 9d55338da78dd6df9e3c20624d770381 142 SUPERFAMILY SSF103481 38 141 6.54E-14 T 14-10-2018 C2I25_18205 22893263f75e05ff46d16039af7e847c 290 SMART SM00382 25 204 6.1E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_18205 22893263f75e05ff46d16039af7e847c 290 SUPERFAMILY SSF52540 2 218 1.0E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18205 22893263f75e05ff46d16039af7e847c 290 Pfam PF00005 ABC transporter 16 155 9.3E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_18205 22893263f75e05ff46d16039af7e847c 290 Gene3D G3DSA:3.40.50.300 1 222 2.1E-50 T 14-10-2018 C2I25_18205 22893263f75e05ff46d16039af7e847c 290 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_23255 85d6b7dfe92521027cd02e0cb38190dd 476 Pfam PF03606 C4-dicarboxylate anaerobic carrier 18 469 5.8E-88 T 14-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 C2I25_08635 34755e6bb6f654750bf231e49d3cb163 234 Gene3D G3DSA:3.60.21.10 1 234 3.5E-60 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I25_08635 34755e6bb6f654750bf231e49d3cb163 234 SUPERFAMILY SSF56300 3 216 1.08E-39 T 14-10-2018 C2I25_08635 34755e6bb6f654750bf231e49d3cb163 234 Pfam PF00149 Calcineurin-like phosphoesterase 3 207 8.5E-17 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I25_12805 917bf3c2d47adb88f1b5561a6f37a907 233 Gene3D G3DSA:3.40.50.300 3 233 1.2E-76 T 14-10-2018 C2I25_12805 917bf3c2d47adb88f1b5561a6f37a907 233 Pfam PF13614 AAA domain 61 191 6.8E-15 T 14-10-2018 IPR025669 AAA domain C2I25_12805 917bf3c2d47adb88f1b5561a6f37a907 233 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 30 231 1.2E-69 T 14-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 C2I25_12805 917bf3c2d47adb88f1b5561a6f37a907 233 SUPERFAMILY SSF52540 50 226 3.41E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_25450 b2509ec84310211825a47915addb28d7 221 SUPERFAMILY SSF81296 35 201 5.74E-63 T 14-10-2018 IPR014756 Immunoglobulin E-set C2I25_25450 b2509ec84310211825a47915addb28d7 221 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 35 198 3.2E-39 T 14-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal C2I25_25450 b2509ec84310211825a47915addb28d7 221 Gene3D G3DSA:2.70.50.50 35 201 3.9E-70 T 14-10-2018 C2I25_09235 e0fcc411b49af4a62df0b5748991ea7c 226 Pfam PF07947 YhhN family 51 222 2.4E-28 T 14-10-2018 IPR012506 YhhN-like GO:0016021 C2I25_10445 6b355dc1f8e406f5b673b7128945b04a 109 Pfam PF14470 Bacterial PH domain 13 104 1.4E-16 T 14-10-2018 IPR039519 YokE-like, PH domain C2I25_16670 a0725cd89b8ac1f1f4d9901cad3ce0be 167 Gene3D G3DSA:1.20.120.450 1 150 1.1E-47 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_16670 a0725cd89b8ac1f1f4d9901cad3ce0be 167 SUPERFAMILY SSF109854 8 152 3.05E-33 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_16670 a0725cd89b8ac1f1f4d9901cad3ce0be 167 Pfam PF05163 DinB family 1 159 1.9E-32 T 14-10-2018 IPR007837 DNA damage-inducible protein DinB C2I25_13560 24e8eab6b9476f8f27de35e7206e73d7 122 Pfam PF03788 LrgA family 18 109 4.5E-23 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 C2I25_16855 7ab40e40bb1dfec25d183e4624effabb 349 Pfam PF10646 Sporulation and spore germination 212 324 4.2E-13 T 14-10-2018 IPR019606 GerMN domain C2I25_16855 7ab40e40bb1dfec25d183e4624effabb 349 Pfam PF10646 Sporulation and spore germination 64 175 3.2E-21 T 14-10-2018 IPR019606 GerMN domain C2I25_16855 7ab40e40bb1dfec25d183e4624effabb 349 SMART SM00909 89 179 1.1E-22 T 14-10-2018 IPR019606 GerMN domain C2I25_16855 7ab40e40bb1dfec25d183e4624effabb 349 SMART SM00909 241 329 8.6E-18 T 14-10-2018 IPR019606 GerMN domain C2I25_18410 0a2809b6d3361485108e53e0b8a178ed 130 Gene3D G3DSA:1.10.940.10 1 130 4.0E-47 T 14-10-2018 IPR035926 NusB-like superfamily C2I25_18410 0a2809b6d3361485108e53e0b8a178ed 130 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 130 23.012 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 C2I25_18410 0a2809b6d3361485108e53e0b8a178ed 130 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 129 9.6E-46 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 C2I25_18410 0a2809b6d3361485108e53e0b8a178ed 130 Pfam PF01029 NusB family 4 127 7.3E-41 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 C2I25_18410 0a2809b6d3361485108e53e0b8a178ed 130 SUPERFAMILY SSF48013 3 126 4.97E-40 T 14-10-2018 IPR035926 NusB-like superfamily C2I25_09390 e39298fed1a5a8ef8dbf45deff2e4798 249 Pfam PF00005 ABC transporter 19 157 1.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_09390 e39298fed1a5a8ef8dbf45deff2e4798 249 SMART SM00382 28 207 2.2E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_09390 e39298fed1a5a8ef8dbf45deff2e4798 249 Gene3D G3DSA:3.40.50.300 1 221 1.4E-55 T 14-10-2018 C2I25_09390 e39298fed1a5a8ef8dbf45deff2e4798 249 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_09390 e39298fed1a5a8ef8dbf45deff2e4798 249 SUPERFAMILY SSF52540 4 227 8.6E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_02165 914d2f40b097c07dec9c6345128760ba 324 Gene3D G3DSA:2.130.10.10 106 323 2.0E-18 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_02165 914d2f40b097c07dec9c6345128760ba 324 SUPERFAMILY SSF110296 62 318 8.37E-30 T 14-10-2018 C2I25_07115 bd9e41b7e52971fd80eb3e6dbe8f57d7 474 Pfam PF13520 Amino acid permease 7 430 8.5E-54 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_07115 bd9e41b7e52971fd80eb3e6dbe8f57d7 474 Gene3D G3DSA:1.20.1740.10 1 474 1.0E-64 T 14-10-2018 C2I25_07115 bd9e41b7e52971fd80eb3e6dbe8f57d7 474 PIRSF PIRSF006060 1 473 3.7E-56 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_22895 b25c94b505fefe2508de4f246259e5f5 317 Gene3D G3DSA:3.20.20.30 1 317 3.1E-127 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_22895 b25c94b505fefe2508de4f246259e5f5 317 Pfam PF00296 Luciferase-like monooxygenase 21 232 3.0E-38 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I25_22895 b25c94b505fefe2508de4f246259e5f5 317 SUPERFAMILY SSF51679 21 315 1.18E-57 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I25_22895 b25c94b505fefe2508de4f246259e5f5 317 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 9 314 1.3E-122 T 14-10-2018 IPR020020 Luciferase-type oxidoreductase C2I25_16800 8e81e97d2e064acafce47b436694f71c 321 Pfam PF13536 Putative multidrug resistance efflux transporter 38 304 4.6E-90 T 14-10-2018 IPR032713 Putative multidrug resistance efflux transporter C2I25_09305 b555b35012f6e3ddf1abf812c918e7bc 198 Pfam PF02342 TerD domain 1 197 7.7E-68 T 14-10-2018 IPR003325 TerD domain C2I25_09305 b555b35012f6e3ddf1abf812c918e7bc 198 Gene3D G3DSA:2.60.60.30 19 194 4.6E-57 T 14-10-2018 C2I25_22765 5dcb7417a4d776e5212c170cd5d9f8e8 229 Pfam PF13027 Protein of unknown function (DUF3888) 132 215 1.3E-19 T 14-10-2018 IPR024984 Protein of unknown function DUF3888 C2I25_01795 0499c3a78b67e92595eeb6f4444f336c 113 Pfam PF13630 SdpI/YhfL protein family 32 98 1.7E-15 T 14-10-2018 IPR025962 SdpI/YhfL protein family C2I25_28230 0fdba99df241ec0151dc307f3ad3e90b 210 PIRSF PIRSF006324 1 209 1.2E-62 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_28230 0fdba99df241ec0151dc307f3ad3e90b 210 Pfam PF01810 LysE type translocator 14 206 2.3E-38 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_05970 0126f2093e87cd5e090d1adf16a37846 42 Pfam PF14149 YhfH-like protein 3 38 3.6E-21 T 14-10-2018 IPR025432 YhfH-like protein C2I25_13465 4db5a310eb303cc0b5d745924e7aa8f5 82 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 14-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site C2I25_13465 4db5a310eb303cc0b5d745924e7aa8f5 82 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 81 5.9E-30 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_13465 4db5a310eb303cc0b5d745924e7aa8f5 82 Gene3D G3DSA:3.30.1340.10 1 82 1.7E-36 T 14-10-2018 IPR035895 HPr-like superfamily C2I25_13465 4db5a310eb303cc0b5d745924e7aa8f5 82 SUPERFAMILY SSF55594 3 81 6.28E-28 T 14-10-2018 IPR035895 HPr-like superfamily C2I25_13465 4db5a310eb303cc0b5d745924e7aa8f5 82 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.1E-21 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_13465 4db5a310eb303cc0b5d745924e7aa8f5 82 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.1E-21 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_13465 4db5a310eb303cc0b5d745924e7aa8f5 82 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.1E-21 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_13465 4db5a310eb303cc0b5d745924e7aa8f5 82 Pfam PF00381 PTS HPr component phosphorylation site 3 81 1.4E-29 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I25_26250 d891c7d27cc4967df5a5cff24e334b5a 214 Gene3D G3DSA:1.20.120.1630 64 213 1.2E-15 T 14-10-2018 C2I25_26250 d891c7d27cc4967df5a5cff24e334b5a 214 Pfam PF06966 Protein of unknown function (DUF1295) 80 206 1.8E-15 T 14-10-2018 IPR010721 Protein of unknown function DUF1295 C2I25_22150 b2d4a46b04f2b7a683788a2d0d2b2e63 167 Pfam PF13302 Acetyltransferase (GNAT) domain 8 147 1.3E-19 T 14-10-2018 IPR000182 GNAT domain C2I25_22150 b2d4a46b04f2b7a683788a2d0d2b2e63 167 Gene3D G3DSA:3.40.630.30 1 163 2.5E-33 T 14-10-2018 C2I25_22150 b2d4a46b04f2b7a683788a2d0d2b2e63 167 SUPERFAMILY SSF55729 2 153 4.72E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_24385 a0b976d6a42f02ec87800aa5f18ca2f9 251 Pfam PF02517 CAAX protease self-immunity 110 211 1.3E-8 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_27630 c16e4dbb12af6172099b30df993e6daf 77 Pfam PF02687 FtsX-like permease family 1 61 1.1E-6 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_23275 e5e908b097c8833b26e10d75d9ceef2f 292 Pfam PF02361 Cobalt transport protein 18 211 1.5E-9 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component C2I25_24580 5098ac63fb927b6e4dd1013eac35001b 343 Pfam PF00487 Fatty acid desaturase 51 290 5.4E-35 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 C2I25_08680 777e612655e0f2dc69cbc238a63a4086 84 Gene3D G3DSA:2.40.50.100 8 76 6.8E-6 T 14-10-2018 C2I25_19940 8050f26a07b48dbc029e07a9551f717f 363 Pfam PF01098 Cell cycle protein 9 362 5.4E-126 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19940 8050f26a07b48dbc029e07a9551f717f 363 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 6 360 1.7E-131 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19940 8050f26a07b48dbc029e07a9551f717f 363 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 319 343 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_19940 8050f26a07b48dbc029e07a9551f717f 363 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 6 359 9.1E-174 T 14-10-2018 IPR013438 Sporulation stage V, protein E C2I25_23100 e8e8ded1832fa4d42d08e17f38eee2c3 126 Gene3D G3DSA:3.10.180.10 1 126 1.4E-39 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_23100 e8e8ded1832fa4d42d08e17f38eee2c3 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 124 3.5E-17 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_23100 e8e8ded1832fa4d42d08e17f38eee2c3 126 SUPERFAMILY SSF54593 1 125 1.88E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_05675 eb4b870ddb31d88a653ba935ac179235 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 8.3E-29 T 14-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I25_05320 02b0fb7bf47d11c118cb11c2582988ef 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 176 1.0E-100 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 C2I25_05320 02b0fb7bf47d11c118cb11c2582988ef 181 Gene3D G3DSA:2.60.120.10 1 181 5.6E-71 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_05320 02b0fb7bf47d11c118cb11c2582988ef 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 177 5.5E-66 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 C2I25_05320 02b0fb7bf47d11c118cb11c2582988ef 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 175 1.1E-68 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 C2I25_05320 02b0fb7bf47d11c118cb11c2582988ef 181 SUPERFAMILY SSF51182 1 179 2.87E-70 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_25415 8dab9f76e6599c7b91d4918340af54df 313 PIRSF PIRSF029792 1 313 2.8E-83 T 14-10-2018 IPR008794 Proline racemase family C2I25_25415 8dab9f76e6599c7b91d4918340af54df 313 Gene3D G3DSA:3.10.310.10 144 289 1.9E-48 T 14-10-2018 C2I25_25415 8dab9f76e6599c7b91d4918340af54df 313 Gene3D G3DSA:3.10.310.10 8 312 1.9E-48 T 14-10-2018 C2I25_25415 8dab9f76e6599c7b91d4918340af54df 313 Pfam PF05544 Proline racemase 10 310 7.3E-28 T 14-10-2018 IPR008794 Proline racemase family C2I25_25415 8dab9f76e6599c7b91d4918340af54df 313 SUPERFAMILY SSF54506 1 310 4.71E-59 T 14-10-2018 C2I25_06690 69c08be4453c6d62dd836a406aa76531 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 64 8.6E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_06690 69c08be4453c6d62dd836a406aa76531 191 Gene3D G3DSA:1.10.357.10 9 181 2.7E-31 T 14-10-2018 C2I25_06690 69c08be4453c6d62dd836a406aa76531 191 SUPERFAMILY SSF46689 10 76 1.35E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_19165 48e916a6f7e9f510a41624d46b4cde9c 172 Gene3D G3DSA:1.20.58.500 4 100 7.0E-15 T 14-10-2018 C2I25_19165 48e916a6f7e9f510a41624d46b4cde9c 172 SUPERFAMILY SSF140663 1 129 1.23E-32 T 14-10-2018 IPR023203 TTHA0068-like superfamily C2I25_19165 48e916a6f7e9f510a41624d46b4cde9c 172 Pfam PF03745 Domain of unknown function (DUF309) 7 66 7.9E-21 T 14-10-2018 IPR005500 Protein of unknown function DUF309 C2I25_04725 b4d58feeec4e1564818955e5981756f5 177 SUPERFAMILY SSF109854 3 173 1.68E-27 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_04725 b4d58feeec4e1564818955e5981756f5 177 Gene3D G3DSA:1.20.120.450 3 173 5.1E-36 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_04725 b4d58feeec4e1564818955e5981756f5 177 Pfam PF12867 DinB superfamily 17 166 5.1E-16 T 14-10-2018 IPR024775 DinB-like domain C2I25_07535 18a145810d5546b5c75bf0e167ee7797 139 Gene3D G3DSA:1.20.1550.10 3 114 5.4E-11 T 14-10-2018 IPR023380 DsbB-like superfamily C2I25_07535 18a145810d5546b5c75bf0e167ee7797 139 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 4 139 24.576 T 14-10-2018 IPR012187 Disulphide bond formation protein BdbC C2I25_07535 18a145810d5546b5c75bf0e167ee7797 139 SUPERFAMILY SSF158442 12 135 8.11E-29 T 14-10-2018 IPR023380 DsbB-like superfamily C2I25_07535 18a145810d5546b5c75bf0e167ee7797 139 Pfam PF02600 Disulfide bond formation protein DsbB 10 115 4.9E-11 T 14-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 C2I25_07535 18a145810d5546b5c75bf0e167ee7797 139 PIRSF PIRSF036659 1 139 1.1E-59 T 14-10-2018 IPR012187 Disulphide bond formation protein BdbC C2I25_02975 5add4d0cd2d9205d5800548dc9cd3c1e 103 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 100 2.6E-24 T 14-10-2018 IPR008407 Branched-chain amino acid transport, AzlD C2I25_21585 a6a14da5e0758b76e81c85a5293340e4 147 SUPERFAMILY SSF54593 5 144 5.99E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21585 a6a14da5e0758b76e81c85a5293340e4 147 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 140 2.5E-9 T 14-10-2018 IPR028973 PhnB-like C2I25_21585 a6a14da5e0758b76e81c85a5293340e4 147 Gene3D G3DSA:3.10.180.10 1 146 3.7E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_03720 bba30b80eee062cdecd4ff24b583408e 381 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 3 373 4.5E-181 T 14-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 C2I25_03720 bba30b80eee062cdecd4ff24b583408e 381 Gene3D G3DSA:3.40.50.2000 175 356 1.3E-138 T 14-10-2018 C2I25_03720 bba30b80eee062cdecd4ff24b583408e 381 Gene3D G3DSA:3.40.50.2000 22 369 1.3E-138 T 14-10-2018 C2I25_03720 bba30b80eee062cdecd4ff24b583408e 381 SUPERFAMILY SSF53756 8 375 8.17E-92 T 14-10-2018 C2I25_03720 bba30b80eee062cdecd4ff24b583408e 381 Pfam PF00534 Glycosyl transferases group 1 188 350 1.1E-42 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 C2I25_03720 bba30b80eee062cdecd4ff24b583408e 381 Pfam PF13439 Glycosyltransferase Family 4 13 177 6.2E-25 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I25_20975 e85a959af4b0361091c3988c01811eea 1138 Pfam PF01391 Collagen triple helix repeat (20 copies) 212 264 4.1E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_20975 e85a959af4b0361091c3988c01811eea 1138 Pfam PF01391 Collagen triple helix repeat (20 copies) 158 213 4.3E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_20975 e85a959af4b0361091c3988c01811eea 1138 Pfam PF01391 Collagen triple helix repeat (20 copies) 413 471 1.2E-6 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_09775 c2fb865f2ec66244c2658cb8337dc1bb 78 Pfam PF05360 yiaA/B two helix domain 9 61 1.9E-18 T 14-10-2018 IPR008024 YiaAB two helix C2I25_12195 7cf2de4b702a8ba6ad7a162442d68366 433 Pfam PF00860 Permease family 8 392 2.9E-59 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I25_03490 45ae836c59654adc4dda1f2be2f93390 412 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 19 405 5.0E-69 T 14-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain C2I25_03490 45ae836c59654adc4dda1f2be2f93390 412 SUPERFAMILY SSF56059 3 403 7.3E-43 T 14-10-2018 C2I25_03490 45ae836c59654adc4dda1f2be2f93390 412 SUPERFAMILY SSF52440 165 277 6.33E-6 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I25_03490 45ae836c59654adc4dda1f2be2f93390 412 Gene3D G3DSA:3.30.1490.330 291 357 1.5E-8 T 14-10-2018 C2I25_12735 ca9b462f3cb72fa19bd20eb65019b8d5 78 Pfam PF06612 Protein of unknown function (DUF1146) 17 64 2.8E-20 T 14-10-2018 IPR009526 Protein of unknown function DUF1146 C2I25_12735 ca9b462f3cb72fa19bd20eb65019b8d5 78 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 10 76 4.3E-31 T 14-10-2018 IPR009526 Protein of unknown function DUF1146 C2I25_12210 903c57236b0162fd72c31ffc5a126318 122 Pfam PF04241 Protein of unknown function (DUF423) 18 104 4.5E-32 T 14-10-2018 IPR006696 Protein of unknown function DUF423 C2I25_28180 e5f4813ce659a6dc8ff5ff4f7722862b 400 Gene3D G3DSA:1.20.1250.20 2 396 3.0E-46 T 14-10-2018 C2I25_28180 e5f4813ce659a6dc8ff5ff4f7722862b 400 Pfam PF07690 Major Facilitator Superfamily 216 393 2.0E-18 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_28180 e5f4813ce659a6dc8ff5ff4f7722862b 400 SUPERFAMILY SSF103473 8 394 3.01E-49 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_03290 fe1b1214223b3914f6947f14f1037efb 244 PIRSF PIRSF005426 1 244 1.4E-91 T 14-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 C2I25_03290 fe1b1214223b3914f6947f14f1037efb 244 Gene3D G3DSA:3.40.109.10 1 244 1.3E-72 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_03290 fe1b1214223b3914f6947f14f1037efb 244 SUPERFAMILY SSF55469 1 243 2.78E-70 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_03290 fe1b1214223b3914f6947f14f1037efb 244 Pfam PF00881 Nitroreductase family 8 65 1.4E-8 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_03290 fe1b1214223b3914f6947f14f1037efb 244 Pfam PF00881 Nitroreductase family 97 161 2.2E-10 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_08395 c6707ed72179c54ba58ecb79f53bf710 243 Gene3D G3DSA:3.40.50.150 31 243 2.9E-51 T 14-10-2018 C2I25_08395 c6707ed72179c54ba58ecb79f53bf710 243 SUPERFAMILY SSF53335 14 243 2.37E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_08395 c6707ed72179c54ba58ecb79f53bf710 243 Pfam PF13649 Methyltransferase domain 49 140 1.6E-13 T 14-10-2018 C2I25_21665 99808c03fc16cecee47fdd138299efbe 112 SUPERFAMILY SSF54593 2 112 4.3E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21665 99808c03fc16cecee47fdd138299efbe 112 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 110 1.5E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_21665 99808c03fc16cecee47fdd138299efbe 112 Gene3D G3DSA:3.10.180.10 2 112 2.0E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_25645 38b176384f30346b1a47e4052097cef3 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 267 5.2E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_25645 38b176384f30346b1a47e4052097cef3 278 SUPERFAMILY SSF161098 87 270 3.66E-38 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_25645 38b176384f30346b1a47e4052097cef3 278 Gene3D G3DSA:1.10.3720.10 83 273 3.2E-34 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_12010 b0dfcc5c16b574fad18dac87a1131b81 323 Pfam PF00535 Glycosyl transferase family 2 6 166 1.6E-33 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I25_12010 b0dfcc5c16b574fad18dac87a1131b81 323 Gene3D G3DSA:3.90.550.10 1 204 1.2E-36 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_12010 b0dfcc5c16b574fad18dac87a1131b81 323 SUPERFAMILY SSF53448 2 223 2.81E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_05360 59cd93866efe648fc6b26954d301add1 250 SUPERFAMILY SSF53335 28 233 1.47E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_05360 59cd93866efe648fc6b26954d301add1 250 Gene3D G3DSA:3.40.50.150 18 233 2.5E-29 T 14-10-2018 C2I25_05360 59cd93866efe648fc6b26954d301add1 250 Pfam PF08241 Methyltransferase domain 48 163 1.1E-19 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_03055 3de6ea53ca94a0072e203578124747c8 261 Pfam PF01464 Transglycosylase SLT domain 145 246 1.0E-24 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 C2I25_03055 3de6ea53ca94a0072e203578124747c8 261 SUPERFAMILY SSF53955 136 256 1.32E-39 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily C2I25_03055 3de6ea53ca94a0072e203578124747c8 261 Gene3D G3DSA:1.10.530.10 35 258 4.0E-43 T 14-10-2018 C2I25_25425 b91471fd54235f42f6062e760209cbc0 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I25_25425 b91471fd54235f42f6062e760209cbc0 494 Gene3D G3DSA:3.40.605.10 24 487 7.2E-210 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I25_25425 b91471fd54235f42f6062e760209cbc0 494 Pfam PF00171 Aldehyde dehydrogenase family 33 489 1.1E-187 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I25_25425 b91471fd54235f42f6062e760209cbc0 494 Gene3D G3DSA:3.40.309.10 270 459 7.2E-210 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I25_25425 b91471fd54235f42f6062e760209cbc0 494 SUPERFAMILY SSF53720 14 492 5.24E-182 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I25_25235 c2dcafe82c4bb3885a17f0273f64f167 527 SUPERFAMILY SSF55486 70 526 6.23E-70 T 14-10-2018 C2I25_25235 c2dcafe82c4bb3885a17f0273f64f167 527 Gene3D G3DSA:1.10.1370.20 157 527 8.7E-92 T 14-10-2018 C2I25_25235 c2dcafe82c4bb3885a17f0273f64f167 527 Pfam PF01432 Peptidase family M3 264 497 2.3E-9 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 C2I25_16125 1ca6927c5a33934390d15f708615d55a 277 Pfam PF12787 EcsC protein family 8 270 2.2E-57 T 14-10-2018 IPR024787 EcsC protein C2I25_16125 1ca6927c5a33934390d15f708615d55a 277 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 33 273 4.0E-7 T 14-10-2018 C2I25_13850 1220e7ec907acbcb8a613d782e8ad04b 144 Pfam PF13058 Protein of unknown function (DUF3920) 17 142 4.0E-68 T 14-10-2018 IPR025033 Protein of unknown function DUF3920 C2I25_28285 06dfd2ee1b9f247a640c8fa0307385e9 68 Pfam PF13619 KTSC domain 8 63 7.4E-16 T 14-10-2018 IPR025309 KTSC domain C2I25_01490 fc8538808e5182bbd581ac6751f28259 219 Pfam PF13460 NAD(P)H-binding 10 125 1.0E-11 T 14-10-2018 IPR016040 NAD(P)-binding domain C2I25_01490 fc8538808e5182bbd581ac6751f28259 219 Gene3D G3DSA:3.40.50.720 1 219 1.1E-59 T 14-10-2018 C2I25_01490 fc8538808e5182bbd581ac6751f28259 219 SUPERFAMILY SSF51735 1 206 2.62E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_07475 04287e0b259398c256610e40a5823ec0 194 Pfam PF11579 Protein of unknown function (DUF3238) 1 193 1.4E-117 T 14-10-2018 IPR021631 Protein of unknown function DUF3238 C2I25_12550 376c1d061587565ba6aa804711474f85 182 Pfam PF02659 Putative manganese efflux pump 33 179 4.2E-39 T 14-10-2018 IPR003810 Putative manganese efflux pump C2I25_12550 376c1d061587565ba6aa804711474f85 182 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 4 182 21.546 T 14-10-2018 IPR022929 Putative manganese efflux pump MntP C2I25_20280 69721bb0bb4826485a0b08c8da145bde 110 Gene3D G3DSA:1.10.10.10 1 109 1.3E-37 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_20280 69721bb0bb4826485a0b08c8da145bde 110 Hamap MF_00245 UPF0122 protein . 2 103 22.481 T 14-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like C2I25_20280 69721bb0bb4826485a0b08c8da145bde 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 101 5.0E-41 T 14-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like C2I25_20280 69721bb0bb4826485a0b08c8da145bde 110 SUPERFAMILY SSF88659 1 102 1.23E-34 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I25_17175 bb6c2619323fa150f81c73c1fc24683c 66 Pfam PF11146 Protein of unknown function (DUF2905) 6 62 1.4E-23 T 14-10-2018 IPR021320 Protein of unknown function DUF2905 C2I25_11445 6e7b83337fbff2fae3e20142ddd8229b 121 Pfam PF06156 Initiation control protein YabA 7 116 2.3E-37 T 14-10-2018 IPR010377 Initiation control protein YabA GO:0006260 C2I25_11445 6e7b83337fbff2fae3e20142ddd8229b 121 PIRSF PIRSF021439 6 121 1.9E-42 T 14-10-2018 IPR010377 Initiation control protein YabA GO:0006260 C2I25_11445 6e7b83337fbff2fae3e20142ddd8229b 121 Hamap MF_01159 Initiation-control protein YabA. 6 120 25.571 T 14-10-2018 IPR010377 Initiation control protein YabA GO:0006260 C2I25_11635 ee1a1505489da0455f9724ef85dbd2e2 70 Pfam PF13275 S4 domain 4 68 4.3E-28 T 14-10-2018 C2I25_11635 ee1a1505489da0455f9724ef85dbd2e2 70 Gene3D G3DSA:3.10.290.10 1 68 2.0E-24 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_11635 ee1a1505489da0455f9724ef85dbd2e2 70 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 4 62 6.6E-32 T 14-10-2018 IPR014330 RNA-binding S4-related,YaaA C2I25_11635 ee1a1505489da0455f9724ef85dbd2e2 70 SUPERFAMILY SSF55174 1 66 8.58E-19 T 14-10-2018 C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 14-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 Pfam PF00232 Glycosyl hydrolase family 1 2 466 1.1E-168 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 378 9.7E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 9.7E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 9.7E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 9.7E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 9.7E-18 T 14-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 Gene3D G3DSA:3.20.20.80 1 469 1.6E-175 T 14-10-2018 C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 SUPERFAMILY SSF51445 1 467 3.47E-169 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_20720 95b02a636a8ee4ec264fbfa2bc49f8cd 469 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 370 378 - T 14-10-2018 IPR018120 Glycoside hydrolase family 1, active site C2I25_24750 687d5cfab5f2c75e596a6a1e0a7a78e0 141 SMART SM00860 15 133 8.4E-5 T 14-10-2018 IPR018958 Knr4/Smi1-like domain C2I25_24750 687d5cfab5f2c75e596a6a1e0a7a78e0 141 Pfam PF14567 SMI1-KNR4 cell-wall 12 135 1.1E-26 T 14-10-2018 C2I25_24750 687d5cfab5f2c75e596a6a1e0a7a78e0 141 Gene3D G3DSA:3.40.1580.10 4 140 1.5E-23 T 14-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I25_24750 687d5cfab5f2c75e596a6a1e0a7a78e0 141 SUPERFAMILY SSF160631 17 138 1.11E-27 T 14-10-2018 C2I25_13915 f7a35aea71892703362376aebfc80a1d 153 SUPERFAMILY SSF141523 27 152 2.62E-30 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I25_13915 f7a35aea71892703362376aebfc80a1d 153 Pfam PF03734 L,D-transpeptidase catalytic domain 31 152 2.5E-21 T 14-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I25_13915 f7a35aea71892703362376aebfc80a1d 153 Gene3D G3DSA:2.40.440.10 14 153 6.0E-38 T 14-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I25_23895 809b53c8d90a7a513dded9cad6de6650 169 Pfam PF12867 DinB superfamily 33 163 1.2E-17 T 14-10-2018 IPR024775 DinB-like domain C2I25_23895 809b53c8d90a7a513dded9cad6de6650 169 Gene3D G3DSA:1.20.120.450 23 168 2.1E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_23895 809b53c8d90a7a513dded9cad6de6650 169 SUPERFAMILY SSF109854 14 164 9.01E-35 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_24010 4d8e2c763290531cda7f0725d3be2a45 128 Pfam PF11181 Heat induced stress protein YflT 11 108 6.5E-32 T 14-10-2018 IPR025889 General stress protein 17M-like domain C2I25_06530 e296aa8967db212e1483b5b462bb3256 116 Gene3D G3DSA:2.30.30.40 50 111 7.8E-7 T 14-10-2018 C2I25_13965 1c2a6bcf04e7c964168e7e854190a111 173 Pfam PF13302 Acetyltransferase (GNAT) domain 7 145 1.0E-22 T 14-10-2018 IPR000182 GNAT domain C2I25_13965 1c2a6bcf04e7c964168e7e854190a111 173 Gene3D G3DSA:3.40.630.30 3 172 3.4E-38 T 14-10-2018 C2I25_13965 1c2a6bcf04e7c964168e7e854190a111 173 SUPERFAMILY SSF55729 3 169 6.82E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.5E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 Gene3D G3DSA:1.10.10.10 2 87 5.2E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 SUPERFAMILY SSF53850 93 292 2.04E-46 T 14-10-2018 C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 Gene3D G3DSA:3.40.190.290 93 297 1.4E-57 T 14-10-2018 C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 Pfam PF03466 LysR substrate binding domain 91 292 2.8E-50 T 14-10-2018 IPR005119 LysR, substrate-binding C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I25_27865 46d0716e45422aea537cd1ebca430f13 300 SUPERFAMILY SSF46785 5 89 2.12E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19130 11ad1072104a97955cf4fbb1aeaf7ebc 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 111 2.2E-41 T 14-10-2018 IPR005562 SpoVA C2I25_19130 11ad1072104a97955cf4fbb1aeaf7ebc 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 1.4E-54 T 14-10-2018 IPR014204 Sporulation stage V, protein AE C2I25_10310 373921e253ac307bfe89c6fca81823f8 471 Gene3D G3DSA:1.20.1740.10 20 469 1.2E-134 T 14-10-2018 C2I25_10310 373921e253ac307bfe89c6fca81823f8 471 Pfam PF13520 Amino acid permease 26 443 6.6E-64 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_10310 373921e253ac307bfe89c6fca81823f8 471 PIRSF PIRSF006060 10 471 1.9E-100 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_01405 ad67c005b1d6c8db253a8fb363995705 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 4 27 2.3E-13 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_01405 ad67c005b1d6c8db253a8fb363995705 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 4 25 2.9E-14 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_01710 4dcb42f93014dec264a7eb71822a4902 610 Pfam PF04183 IucA / IucC family 147 388 1.8E-70 T 14-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 C2I25_01710 4dcb42f93014dec264a7eb71822a4902 610 Gene3D G3DSA:1.10.510.40 378 597 5.5E-57 T 14-10-2018 C2I25_01710 4dcb42f93014dec264a7eb71822a4902 610 Pfam PF06276 Ferric iron reductase FhuF-like transporter 409 579 1.3E-32 T 14-10-2018 IPR022770 Ferric iron reductase FhuF domain C2I25_23015 9902d9fbd0510fcb277f718212b263f5 79 Pfam PF13061 Protein of unknown function (DUF3923) 5 68 2.4E-25 T 14-10-2018 IPR025037 Protein of unknown function DUF3923 C2I25_02605 8f522b838420b2f9247edb24d01251b2 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 3.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_02605 8f522b838420b2f9247edb24d01251b2 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 3.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_02605 8f522b838420b2f9247edb24d01251b2 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 3.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_02605 8f522b838420b2f9247edb24d01251b2 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 3.2E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I25_02605 8f522b838420b2f9247edb24d01251b2 432 Gene3D G3DSA:3.30.565.10 274 425 2.1E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_02605 8f522b838420b2f9247edb24d01251b2 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 425 1.2E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_02605 8f522b838420b2f9247edb24d01251b2 432 SUPERFAMILY SSF55874 281 423 1.31E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_02605 8f522b838420b2f9247edb24d01251b2 432 SMART SM00387 314 426 1.0E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_21370 f0dcedf9e305673b219473c23bf42a8a 202 Gene3D G3DSA:3.40.50.1950 8 183 2.1E-47 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I25_21370 f0dcedf9e305673b219473c23bf42a8a 202 Pfam PF02441 Flavoprotein 11 163 4.4E-35 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 C2I25_21370 f0dcedf9e305673b219473c23bf42a8a 202 SUPERFAMILY SSF52507 7 185 4.58E-47 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I25_08520 55a3b7ffc6f3749812a7eb82c32cac80 471 PIRSF PIRSF006060 5 470 7.2E-93 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_08520 55a3b7ffc6f3749812a7eb82c32cac80 471 Pfam PF13520 Amino acid permease 26 430 1.6E-64 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I25_08520 55a3b7ffc6f3749812a7eb82c32cac80 471 Gene3D G3DSA:1.20.1740.10 20 466 1.6E-129 T 14-10-2018 C2I25_27225 a46e59af418a43ef8a5c447d0914683f 152 Gene3D G3DSA:2.60.40.3720 36 152 1.9E-50 T 14-10-2018 C2I25_27225 a46e59af418a43ef8a5c447d0914683f 152 Pfam PF16723 Domain of unknown function (DUF5065) 2 152 1.1E-57 T 14-10-2018 IPR031998 Protein of unknown function DUF5065 C2I25_24925 c772346b65a492aa035c72d6fb3b7373 267 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 35 263 6.0E-81 T 14-10-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 C2I25_24925 c772346b65a492aa035c72d6fb3b7373 267 SUPERFAMILY SSF110710 5 266 7.32E-97 T 14-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like C2I25_03465 87b27c36e033c2a2056e6727c1222a7c 397 Pfam PF01757 Acyltransferase family 6 353 9.8E-29 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I25_04235 e867abcbb7deee3b6d30c0943d5a8f92 438 Pfam PF03553 Na+/H+ antiporter family 71 211 7.1E-13 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I25_04235 e867abcbb7deee3b6d30c0943d5a8f92 438 Pfam PF03553 Na+/H+ antiporter family 240 421 3.2E-13 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I25_04590 20b439f65fb68a53070b0ff1ffe4f7d6 132 Pfam PF07179 SseB protein N-terminal domain 9 120 1.0E-14 T 14-10-2018 IPR009839 SseB protein N-terminal domain C2I25_02620 49999b1209e7095713ac4781917d61d3 423 SUPERFAMILY SSF118215 6 402 1.31E-125 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 Gene3D G3DSA:1.10.3860.10 1 419 1.3E-135 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.5E-37 T 14-10-2018 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 1.5E-37 T 14-10-2018 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 1.5E-37 T 14-10-2018 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 1.5E-37 T 14-10-2018 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.5E-37 T 14-10-2018 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 1.5E-37 T 14-10-2018 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 1.5E-37 T 14-10-2018 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 219 238 1.5E-37 T 14-10-2018 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 9.8E-126 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I25_02620 49999b1209e7095713ac4781917d61d3 423 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I25_01260 9eb88b4ef2251d1003f8fe8223295dc7 378 Gene3D G3DSA:1.20.1250.20 1 375 3.5E-56 T 14-10-2018 C2I25_01260 9eb88b4ef2251d1003f8fe8223295dc7 378 Pfam PF07690 Major Facilitator Superfamily 7 314 1.5E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_01260 9eb88b4ef2251d1003f8fe8223295dc7 378 SUPERFAMILY SSF103473 2 376 3.53E-63 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_23450 b74f9a9c0212302911fd225dec796a15 390 SUPERFAMILY SSF51445 86 364 4.68E-15 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_23450 b74f9a9c0212302911fd225dec796a15 390 Gene3D G3DSA:3.20.20.80 63 390 6.9E-43 T 14-10-2018 C2I25_25175 4c902e81ba87c27715ef4989177effa2 236 Pfam PF04519 Polymer-forming cytoskeletal 20 81 9.5E-9 T 14-10-2018 IPR007607 Bactofilin A/B C2I25_25175 4c902e81ba87c27715ef4989177effa2 236 Pfam PF04519 Polymer-forming cytoskeletal 45 120 5.6E-11 T 14-10-2018 IPR007607 Bactofilin A/B C2I25_24240 c315c6d32c9b90df4a4e9cf2d50320e9 320 Pfam PF06166 Protein of unknown function (DUF979) 8 318 5.1E-124 T 14-10-2018 IPR009323 Protein of unknown function DUF979 C2I25_23955 d53f5fa6107b7bdc66061d0f15bb6240 170 SUPERFAMILY SSF53056 3 159 1.96E-17 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 C2I25_23955 d53f5fa6107b7bdc66061d0f15bb6240 170 Gene3D G3DSA:3.40.1050.10 1 159 4.4E-11 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 C2I25_11280 3ed94f90eeef1d4cd1c5346226f1c6ce 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 174 3.3E-69 T 14-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 C2I25_11280 3ed94f90eeef1d4cd1c5346226f1c6ce 180 Gene3D G3DSA:3.40.50.2020 1 180 1.3E-67 T 14-10-2018 C2I25_11280 3ed94f90eeef1d4cd1c5346226f1c6ce 180 SUPERFAMILY SSF53271 4 178 2.17E-60 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_11280 3ed94f90eeef1d4cd1c5346226f1c6ce 180 Pfam PF00156 Phosphoribosyl transferase domain 15 160 6.1E-25 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_04635 7df744c6974e21b0137c4aaa1bad7b16 232 Pfam PF00005 ABC transporter 21 155 4.9E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_04635 7df744c6974e21b0137c4aaa1bad7b16 232 SUPERFAMILY SSF52540 4 215 5.53E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_04635 7df744c6974e21b0137c4aaa1bad7b16 232 Gene3D G3DSA:3.40.50.300 1 231 5.0E-50 T 14-10-2018 C2I25_04635 7df744c6974e21b0137c4aaa1bad7b16 232 SMART SM00382 29 204 1.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 80 98 3.2E-13 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 17 39 3.2E-13 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 169 186 3.2E-13 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 253 270 3.2E-13 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 292 315 3.2E-13 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 142 163 3.2E-13 T 14-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 Pfam PF05977 Transmembrane secretion effector 12 315 2.0E-24 T 14-10-2018 IPR010290 Transmembrane secretion effector C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 SUPERFAMILY SSF103473 12 394 9.02E-37 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_03260 5fdc6c4916d83e929f3d2b3f112d5284 404 Gene3D G3DSA:1.20.1250.20 10 393 3.8E-26 T 14-10-2018 C2I25_16115 99b8ec273d0906b5d3ae2725fa137fd3 144 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I25_16115 99b8ec273d0906b5d3ae2725fa137fd3 144 Pfam PF00293 NUDIX domain 5 124 1.2E-10 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I25_16115 99b8ec273d0906b5d3ae2725fa137fd3 144 SUPERFAMILY SSF55811 3 122 4.74E-17 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I25_16115 99b8ec273d0906b5d3ae2725fa137fd3 144 Gene3D G3DSA:3.90.79.10 3 143 5.6E-20 T 14-10-2018 C2I25_26290 1d468f4bd70219be220c481101695229 152 ProDom PD093362 MEMBRANE UNCHARACTERIZED YXJN HOMOLOG B.SUBTILIS PROTEIN TRANSMEMBRANE 1 151 4.0E-51 T 14-10-2018 IPR020223 Uncharacterised protein YxjN C2I25_26290 1d468f4bd70219be220c481101695229 152 Pfam PF07301 Protein of unknown function (DUF1453) 5 147 2.3E-6 T 14-10-2018 IPR009916 Protein of unknown function DUF1453 C2I25_07415 f187ea46cfc55ce5568c3a8206e7d120 411 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 112 268 8.3E-36 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_07415 f187ea46cfc55ce5568c3a8206e7d120 411 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 112 268 7.9E-42 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_07415 f187ea46cfc55ce5568c3a8206e7d120 411 Gene3D G3DSA:1.10.260.150 73 398 2.1E-81 T 14-10-2018 C2I25_06840 22b30369df9469f32a03fb36d42f23f3 273 Gene3D G3DSA:3.60.15.10 10 240 3.8E-23 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_06840 22b30369df9469f32a03fb36d42f23f3 273 SUPERFAMILY SSF56281 24 229 2.18E-26 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_06840 22b30369df9469f32a03fb36d42f23f3 273 SMART SM00849 25 207 9.8E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_07565 64685b7fe23244c4cc0a2bdee21f3139 313 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I25_07565 64685b7fe23244c4cc0a2bdee21f3139 313 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 34 58 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I25_07565 64685b7fe23244c4cc0a2bdee21f3139 313 Pfam PF00294 pfkB family carbohydrate kinase 1 305 7.6E-80 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB C2I25_07565 64685b7fe23244c4cc0a2bdee21f3139 313 Gene3D G3DSA:3.40.1190.20 1 312 9.8E-85 T 14-10-2018 IPR029056 Ribokinase-like C2I25_07565 64685b7fe23244c4cc0a2bdee21f3139 313 SUPERFAMILY SSF53613 1 311 2.81E-79 T 14-10-2018 IPR029056 Ribokinase-like C2I25_21605 b0b4e940f31d21c5e7cc26c1ae6b8be1 268 Pfam PF12679 ABC-2 family transporter protein 28 266 3.2E-13 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I25_03425 99f6fccf1ea3c93ec4c73adcb0621967 521 Gene3D G3DSA:2.160.20.10 9 131 6.0E-13 T 14-10-2018 IPR012334 Pectin lyase fold C2I25_03425 99f6fccf1ea3c93ec4c73adcb0621967 521 SUPERFAMILY SSF51126 1 288 3.14E-20 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor C2I25_14525 dfc7e8fc6625fa54ff99669836756e8d 105 Pfam PF14068 Putative membrane protein 6 105 8.3E-42 T 14-10-2018 IPR025917 Putative membrane protein YuiB C2I25_15400 3844839a08fd7b1dd564ecdbaacea80f 127 Pfam PF03899 ATP synthase I chain 13 103 6.8E-14 T 14-10-2018 IPR005598 ATP synthase protein I C2I25_15400 3844839a08fd7b1dd564ecdbaacea80f 127 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 21 123 1.0E-54 T 14-10-2018 C2I25_27140 de716fde5cef908c984eb6f799d2e9e1 322 PIRSF PIRSF037004 1 316 2.6E-124 T 14-10-2018 IPR017087 Uncharacterised conserved protein UCP037004 C2I25_27140 de716fde5cef908c984eb6f799d2e9e1 322 Pfam PF04463 Protein of unknown function (DUF523) 9 149 1.2E-35 T 14-10-2018 IPR007553 Domain of unknown function DUF523 C2I25_27140 de716fde5cef908c984eb6f799d2e9e1 322 Pfam PF08349 Protein of unknown function (DUF1722) 191 307 3.0E-41 T 14-10-2018 IPR013560 Domain of unknown function DUF1722 C2I25_02795 f15ec4a39556d44a21cdd1f783a6450c 281 Pfam PF03773 Predicted permease 1 273 3.9E-68 T 14-10-2018 IPR005524 Predicted permease DUF318 C2I25_23730 966df1429830887a5d0ff75a1de5cfa8 139 SUPERFAMILY SSF46785 7 136 1.48E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_23730 966df1429830887a5d0ff75a1de5cfa8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 8.5E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_23730 966df1429830887a5d0ff75a1de5cfa8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 8.5E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_23730 966df1429830887a5d0ff75a1de5cfa8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 8.5E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_23730 966df1429830887a5d0ff75a1de5cfa8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 8.5E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_23730 966df1429830887a5d0ff75a1de5cfa8 139 Pfam PF01047 MarR family 32 88 4.9E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_23730 966df1429830887a5d0ff75a1de5cfa8 139 SMART SM00347 24 124 4.1E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_23730 966df1429830887a5d0ff75a1de5cfa8 139 Gene3D G3DSA:1.10.10.10 2 135 2.2E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15045 3664c8465d74b117be73251b790e6410 256 SMART SM00382 33 221 1.3E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_15045 3664c8465d74b117be73251b790e6410 256 Gene3D G3DSA:3.40.50.300 1 249 2.7E-65 T 14-10-2018 C2I25_15045 3664c8465d74b117be73251b790e6410 256 Pfam PF00005 ABC transporter 24 172 1.0E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_15045 3664c8465d74b117be73251b790e6410 256 SUPERFAMILY SSF52540 4 228 3.44E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PIRSF PIRSF000126 2 257 2.5E-58 T 14-10-2018 C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 Gene3D G3DSA:3.40.50.720 1 263 2.2E-75 T 14-10-2018 C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.3E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 SUPERFAMILY SSF51735 2 254 5.68E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 Pfam PF00106 short chain dehydrogenase 8 195 5.2E-61 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.3E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.3E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.3E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_18750 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.3E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I25_22825 eca492348d39f89111035c674f3ad182 404 SUPERFAMILY SSF103473 12 395 2.35E-61 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_22825 eca492348d39f89111035c674f3ad182 404 Pfam PF07690 Major Facilitator Superfamily 24 334 6.5E-43 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_22825 eca492348d39f89111035c674f3ad182 404 PRINTS PR01035 Tetracycline resistance protein signature 26 42 2.4E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_22825 eca492348d39f89111035c674f3ad182 404 PRINTS PR01035 Tetracycline resistance protein signature 174 194 2.4E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_22825 eca492348d39f89111035c674f3ad182 404 PRINTS PR01035 Tetracycline resistance protein signature 56 75 2.4E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_22825 eca492348d39f89111035c674f3ad182 404 PRINTS PR01035 Tetracycline resistance protein signature 114 135 2.4E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_22825 eca492348d39f89111035c674f3ad182 404 PRINTS PR01035 Tetracycline resistance protein signature 378 397 2.4E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_22825 eca492348d39f89111035c674f3ad182 404 Gene3D G3DSA:1.20.1250.20 9 396 3.8E-49 T 14-10-2018 C2I25_21525 13b193563c0812e62d835bd1b6dcaced 139 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 122 9.6E-30 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 C2I25_21525 13b193563c0812e62d835bd1b6dcaced 139 Gene3D G3DSA:3.10.129.10 4 136 3.2E-33 T 14-10-2018 C2I25_21525 13b193563c0812e62d835bd1b6dcaced 139 Pfam PF03061 Thioesterase superfamily 18 102 7.6E-14 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I25_21525 13b193563c0812e62d835bd1b6dcaced 139 SUPERFAMILY SSF54637 2 133 3.09E-36 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_21525 13b193563c0812e62d835bd1b6dcaced 139 PIRSF PIRSF003230 1 135 6.8E-30 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 C2I25_02945 d3ff07bd623cdb1ce51e6db2b7a39197 404 SUPERFAMILY SSF47413 2 68 3.94E-15 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_02945 d3ff07bd623cdb1ce51e6db2b7a39197 404 Pfam PF12844 Helix-turn-helix domain 5 63 6.3E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_02945 d3ff07bd623cdb1ce51e6db2b7a39197 404 Gene3D G3DSA:1.25.40.10 1 270 4.5E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_02945 d3ff07bd623cdb1ce51e6db2b7a39197 404 Gene3D G3DSA:1.25.40.10 271 401 2.4E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_02945 d3ff07bd623cdb1ce51e6db2b7a39197 404 SMART SM00530 7 61 4.2E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_02945 d3ff07bd623cdb1ce51e6db2b7a39197 404 SUPERFAMILY SSF48452 162 395 4.22E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_21315 96b1cc8c25817770a2d6e8c578bf240e 268 Gene3D G3DSA:3.40.630.30 69 242 9.6E-17 T 14-10-2018 C2I25_21315 96b1cc8c25817770a2d6e8c578bf240e 268 SUPERFAMILY SSF55729 93 240 1.29E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_28195 f207125619e649b6d85428313c0dfb8f 99 Gene3D G3DSA:1.10.10.10 3 98 7.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_28195 f207125619e649b6d85428313c0dfb8f 99 Pfam PF01022 Bacterial regulatory protein, arsR family 26 66 1.4E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_28195 f207125619e649b6d85428313c0dfb8f 99 SUPERFAMILY SSF46785 13 86 2.03E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_28195 f207125619e649b6d85428313c0dfb8f 99 SMART SM00418 19 97 7.3E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_03360 ec8ad3efdb4fc7227c45cd7cc98e2333 242 Pfam PF08892 YqcI/YcgG family 29 236 1.1E-70 T 14-10-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG C2I25_03860 5ca76bf447b6dcb9b02715cff89e8a89 237 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 13 237 2.0E-127 T 14-10-2018 C2I25_17035 a4f7623525e39e245e563427c37396dd 265 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 218 2.9E-26 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain C2I25_17035 a4f7623525e39e245e563427c37396dd 265 PIRSF PIRSF003092 1 265 3.5E-93 T 14-10-2018 IPR025501 ATP binding protein MinD C2I25_17035 a4f7623525e39e245e563427c37396dd 265 SUPERFAMILY SSF52540 5 258 8.52E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_17035 a4f7623525e39e245e563427c37396dd 265 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 262 1.2E-122 T 14-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 C2I25_17035 a4f7623525e39e245e563427c37396dd 265 Gene3D G3DSA:3.40.50.300 3 254 1.6E-72 T 14-10-2018 C2I25_00100 6cec5f04a900a899baa1c4007e57c9b5 225 Pfam PF10924 Protein of unknown function (DUF2711) 9 224 1.3E-113 T 14-10-2018 IPR024250 Protein of unknown function DUF2711 C2I25_00100 6cec5f04a900a899baa1c4007e57c9b5 225 ProDom PD114754 YWBB 1 224 8.0E-114 T 14-10-2018 IPR024250 Protein of unknown function DUF2711 C2I25_02810 512fa8a0c41c77aef1f6681dfa9546ec 103 Pfam PF12650 Domain of unknown function (DUF3784) 10 95 8.4E-7 T 14-10-2018 IPR017259 Uncharacterised conserved protein UCP037672 C2I25_15175 7f982870837e9ccb3063b3aaf800b783 168 Pfam PF13785 Domain of unknown function (DUF4178) 28 158 4.9E-26 T 14-10-2018 IPR025235 Domain of unknown function DUF4178 C2I25_03380 37d4b1dc92261db31bc574fa45c92b42 219 Pfam PF13456 Reverse transcriptase-like 78 205 4.0E-15 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 C2I25_03380 37d4b1dc92261db31bc574fa45c92b42 219 Gene3D G3DSA:3.30.420.10 73 217 6.2E-28 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I25_03380 37d4b1dc92261db31bc574fa45c92b42 219 SUPERFAMILY SSF53098 74 208 1.52E-18 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily C2I25_26075 124d88c89af6d895ea84db0bbd6fa3f3 157 SUPERFAMILY SSF55729 1 142 6.97E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26075 124d88c89af6d895ea84db0bbd6fa3f3 157 Gene3D G3DSA:3.40.630.30 3 157 1.4E-16 T 14-10-2018 C2I25_26075 124d88c89af6d895ea84db0bbd6fa3f3 157 Pfam PF00583 Acetyltransferase (GNAT) family 53 134 8.0E-8 T 14-10-2018 IPR000182 GNAT domain C2I25_12865 5609e2aa032ef87c28eaddc9deb9060b 304 Hamap MF_01140 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU [tagU]. 2 302 48.892 T 14-10-2018 IPR023734 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU C2I25_12865 5609e2aa032ef87c28eaddc9deb9060b 304 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 78 219 1.5E-49 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_12865 5609e2aa032ef87c28eaddc9deb9060b 304 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 77 220 6.4E-52 T 14-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I25_12865 5609e2aa032ef87c28eaddc9deb9060b 304 Gene3D G3DSA:1.10.260.150 42 304 4.0E-89 T 14-10-2018 C2I25_08665 6f880ba7d0f6f0f629112325357da3d3 226 Gene3D G3DSA:3.40.630.30 98 215 5.3E-16 T 14-10-2018 C2I25_08665 6f880ba7d0f6f0f629112325357da3d3 226 SUPERFAMILY SSF55729 120 214 1.23E-5 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_08665 6f880ba7d0f6f0f629112325357da3d3 226 Pfam PF12746 GNAT acetyltransferase 140 214 2.9E-7 T 14-10-2018 IPR027365 GNAT acetyltransferase YdfB-like C2I25_18620 b568a5e1d5af005f09532a8bcef2490b 392 Pfam PF01098 Cell cycle protein 14 383 1.6E-85 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_18620 b568a5e1d5af005f09532a8bcef2490b 392 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 342 366 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_24675 e018288145790a9d51cef19369775360 120 SUPERFAMILY SSF51182 23 103 4.23E-24 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_24675 e018288145790a9d51cef19369775360 120 Pfam PF07883 Cupin domain 30 99 1.8E-19 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_24675 e018288145790a9d51cef19369775360 120 Gene3D G3DSA:2.60.120.10 3 119 3.5E-22 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_22160 f4f3f7900f075ff7f6e5beee6071c407 463 Gene3D G3DSA:3.30.70.2740 336 417 5.9E-11 T 14-10-2018 C2I25_22160 f4f3f7900f075ff7f6e5beee6071c407 463 Pfam PF01565 FAD binding domain 43 179 2.3E-40 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I25_22160 f4f3f7900f075ff7f6e5beee6071c407 463 SUPERFAMILY SSF55103 220 457 1.64E-63 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 C2I25_22160 f4f3f7900f075ff7f6e5beee6071c407 463 Gene3D G3DSA:1.10.45.10 418 457 1.6E-8 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 C2I25_22160 f4f3f7900f075ff7f6e5beee6071c407 463 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 456 9.5E-57 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 C2I25_22160 f4f3f7900f075ff7f6e5beee6071c407 463 Gene3D G3DSA:3.30.465.40 5 237 4.4E-72 T 14-10-2018 C2I25_22160 f4f3f7900f075ff7f6e5beee6071c407 463 SUPERFAMILY SSF56176 4 217 7.01E-66 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I25_22605 722aec0b0119c3ffde900b0faf5e5d40 107 Gene3D G3DSA:1.10.10.10 1 107 4.1E-40 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22605 722aec0b0119c3ffde900b0faf5e5d40 107 Pfam PF01638 HxlR-like helix-turn-helix 15 100 8.6E-35 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_22605 722aec0b0119c3ffde900b0faf5e5d40 107 SUPERFAMILY SSF46785 4 102 3.84E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01195 87760f2b61478c112a0e611b411c4f2d 186 Pfam PF13563 2'-5' RNA ligase superfamily 56 161 1.0E-10 T 14-10-2018 C2I25_01195 87760f2b61478c112a0e611b411c4f2d 186 Gene3D G3DSA:3.90.1140.10 2 181 8.2E-18 T 14-10-2018 C2I25_01195 87760f2b61478c112a0e611b411c4f2d 186 SUPERFAMILY SSF55144 2 163 1.15E-15 T 14-10-2018 IPR009097 Cyclic phosphodiesterase C2I25_17625 4c6d9321c0e14798ad8af56a903eb316 118 Gene3D G3DSA:3.30.460.10 1 108 7.8E-38 T 14-10-2018 C2I25_17625 4c6d9321c0e14798ad8af56a903eb316 118 SUPERFAMILY SSF81301 1 113 1.16E-39 T 14-10-2018 C2I25_17625 4c6d9321c0e14798ad8af56a903eb316 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 105 24.564 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS C2I25_17625 4c6d9321c0e14798ad8af56a903eb316 118 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 4.6E-26 T 14-10-2018 C2I25_17625 4c6d9321c0e14798ad8af56a903eb316 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 9 104 3.1E-36 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS C2I25_25375 5752b2316204a3afcd6b371fb26ad17b 102 ProDom PD068665 YXCD 1 102 2.0E-51 T 14-10-2018 IPR020516 Uncharacterised protein family YxcD C2I25_25375 5752b2316204a3afcd6b371fb26ad17b 102 Pfam PF10850 Protein of unknown function (DUF2653) 1 88 1.5E-38 T 14-10-2018 IPR020516 Uncharacterised protein family YxcD C2I25_01315 af0f586e639f739d772f0b4f7c770f64 165 Pfam PF00583 Acetyltransferase (GNAT) family 36 138 2.1E-17 T 14-10-2018 IPR000182 GNAT domain C2I25_01315 af0f586e639f739d772f0b4f7c770f64 165 Gene3D G3DSA:3.40.630.30 1 165 1.6E-43 T 14-10-2018 C2I25_01315 af0f586e639f739d772f0b4f7c770f64 165 SUPERFAMILY SSF55729 2 164 9.81E-35 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_00810 48758be73621d3b3747cc0c239ba83fe 160 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 7 151 3.3E-20 T 14-10-2018 IPR006524 Transcription activator, ArpU family C2I25_05700 547dc63319816860537a37297ce5cbb7 71 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 6.5E-24 T 14-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I25_20665 5cd7a6916a4102875504d60db753944c 180 Pfam PF10628 Outer spore coat protein E (CotE) 4 175 1.5E-65 T 14-10-2018 IPR018901 Spore coat protein CotE C2I25_21815 b83add4d4275c7d1a4c59ffd5eb3d756 92 ProDom PD745092 MEMBRANE YHDT SODIUM/PANTOTHENATE TRANSMEMBRANE INNER SYMPORTER Y0210 INTEGRAL PROTEIN-LIKE PM1090 7 88 1.0E-40 T 14-10-2018 IPR010398 Protein of unknown function DUF997 C2I25_21815 b83add4d4275c7d1a4c59ffd5eb3d756 92 Pfam PF06196 Protein of unknown function (DUF997) 12 88 3.2E-32 T 14-10-2018 IPR010398 Protein of unknown function DUF997 C2I25_25260 d1dc56e4813d081d6494eba994d2e17c 150 Gene3D G3DSA:3.40.630.30 3 146 2.9E-28 T 14-10-2018 C2I25_25260 d1dc56e4813d081d6494eba994d2e17c 150 SUPERFAMILY SSF55729 8 143 1.67E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25260 d1dc56e4813d081d6494eba994d2e17c 150 Pfam PF00583 Acetyltransferase (GNAT) family 41 135 6.7E-8 T 14-10-2018 IPR000182 GNAT domain C2I25_15755 17da42d7c3db96c34784723ad704ddcf 92 Pfam PF14165 YtzH-like protein 3 88 1.4E-38 T 14-10-2018 IPR025547 YtzH-like protein C2I25_26045 d2405979f32b4450e9563a4423c0280c 126 PIRSF PIRSF026568 1 126 3.5E-82 T 14-10-2018 IPR014527 Excinuclease GIY-YIG catalytic domain-containing uncharacterised conserved protein C2I25_26045 d2405979f32b4450e9563a4423c0280c 126 Pfam PF01541 GIY-YIG catalytic domain 45 119 3.0E-12 T 14-10-2018 IPR000305 GIY-YIG endonuclease C2I25_26045 d2405979f32b4450e9563a4423c0280c 126 Gene3D G3DSA:3.40.1440.10 39 124 9.7E-14 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I25_26045 d2405979f32b4450e9563a4423c0280c 126 SUPERFAMILY SSF82771 44 122 1.57E-13 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I25_26045 d2405979f32b4450e9563a4423c0280c 126 SMART SM00465 45 124 7.0E-15 T 14-10-2018 IPR000305 GIY-YIG endonuclease C2I25_05560 ceb2dca6ed9f8db5681c1a4809c113fe 59 Pfam PF14168 YjzC-like protein 1 55 1.5E-27 T 14-10-2018 IPR025549 YjzC-like protein C2I25_20980 4a3edd7f219a1a2958fda373006c4544 321 Gene3D G3DSA:1.10.150.130 6 101 4.5E-11 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I25_20980 4a3edd7f219a1a2958fda373006c4544 321 Gene3D G3DSA:1.10.443.10 110 316 2.0E-16 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I25_20980 4a3edd7f219a1a2958fda373006c4544 321 SUPERFAMILY SSF56349 117 317 1.77E-19 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I25_20980 4a3edd7f219a1a2958fda373006c4544 321 SUPERFAMILY SSF47823 15 110 8.24E-7 T 14-10-2018 C2I25_20980 4a3edd7f219a1a2958fda373006c4544 321 Pfam PF00589 Phage integrase family 150 312 3.1E-9 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I25_20980 4a3edd7f219a1a2958fda373006c4544 321 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 11 86 4.2E-7 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I25_17835 9cc67b29847180137d774fa010f936cb 235 SUPERFAMILY SSF53335 10 106 1.57E-7 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_17835 9cc67b29847180137d774fa010f936cb 235 Gene3D G3DSA:3.40.50.150 1 163 9.9E-53 T 14-10-2018 C2I25_17835 9cc67b29847180137d774fa010f936cb 235 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 231 3.3E-72 T 14-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 C2I25_17835 9cc67b29847180137d774fa010f936cb 235 PIRSF PIRSF018637 4 235 1.8E-82 T 14-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 C2I25_22040 f65bc6ab7a98b1c329779a696ecea564 689 SUPERFAMILY SSF53448 57 292 4.22E-19 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_22040 f65bc6ab7a98b1c329779a696ecea564 689 SUPERFAMILY SSF53448 373 654 9.28E-19 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_21690 caa67e8a595454b770e527c4103726be 378 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 199 375 3.4E-26 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_21690 caa67e8a595454b770e527c4103726be 378 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 378 2.4E-58 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_21690 caa67e8a595454b770e527c4103726be 378 Gene3D G3DSA:3.30.300.210 232 378 2.3E-25 T 14-10-2018 IPR038501 Spore germination GerAC superfamily C2I25_08325 7f22d2256a09a4646428862f6af742ba 374 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 201 371 2.1E-31 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_08325 7f22d2256a09a4646428862f6af742ba 374 Gene3D G3DSA:3.30.300.210 222 374 4.3E-22 T 14-10-2018 IPR038501 Spore germination GerAC superfamily C2I25_08325 7f22d2256a09a4646428862f6af742ba 374 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 373 8.5E-95 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_21120 d98a1db14e887b40975f0bd3f8499bd8 66 Pfam PF13043 Domain of unknown function (DUF3903) 25 64 3.2E-27 T 14-10-2018 IPR025000 Protein of unknown function DUF3903 C2I25_06325 0a58383de4912d79028e31fb793b06aa 314 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 271 1.1E-19 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_06325 0a58383de4912d79028e31fb793b06aa 314 SUPERFAMILY SSF54593 1 297 4.19E-47 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_06325 0a58383de4912d79028e31fb793b06aa 314 Gene3D G3DSA:3.10.180.10 5 310 4.0E-130 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_06325 0a58383de4912d79028e31fb793b06aa 314 Gene3D G3DSA:3.10.180.10 66 215 4.0E-130 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_03660 ddcbeb077a3a28dfa5df0aa0b33254ad 235 Gene3D G3DSA:1.10.10.630 126 201 1.0E-31 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_03660 ddcbeb077a3a28dfa5df0aa0b33254ad 235 Gene3D G3DSA:1.10.10.10 1 115 3.7E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_03660 ddcbeb077a3a28dfa5df0aa0b33254ad 235 SUPERFAMILY SSF46785 29 86 6.2E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_03660 ddcbeb077a3a28dfa5df0aa0b33254ad 235 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 200 1.2E-25 T 14-10-2018 IPR006343 DnaD domain C2I25_03660 ddcbeb077a3a28dfa5df0aa0b33254ad 235 Pfam PF07261 Replication initiation and membrane attachment 131 201 6.1E-26 T 14-10-2018 IPR006343 DnaD domain C2I25_03660 ddcbeb077a3a28dfa5df0aa0b33254ad 235 SUPERFAMILY SSF158499 130 195 1.83E-19 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_04035 c156ba009d8170022be8d41a127fec3d 173 Gene3D G3DSA:3.40.30.10 28 173 1.4E-53 T 14-10-2018 C2I25_04035 c156ba009d8170022be8d41a127fec3d 173 Pfam PF00578 AhpC/TSA family 37 153 7.8E-37 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I25_04035 c156ba009d8170022be8d41a127fec3d 173 Hamap MF_01319 Thiol-disulfide oxidoreductase ResA [resA]. 1 173 46.307 T 14-10-2018 IPR023555 Thiol-disulphide oxidoreductase ResA GO:0005886|GO:0015036|GO:0017004 C2I25_04035 c156ba009d8170022be8d41a127fec3d 173 SUPERFAMILY SSF52833 9 170 6.84E-46 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_26405 cee6dc9a3866b96f008f571fff22aafa 182 Hamap MF_01572 UPF0397 protein . 2 181 21.411 T 14-10-2018 IPR022914 Protein of unknown function UPF0397 C2I25_26405 cee6dc9a3866b96f008f571fff22aafa 182 Gene3D G3DSA:1.10.1760.20 1 173 3.1E-17 T 14-10-2018 C2I25_26405 cee6dc9a3866b96f008f571fff22aafa 182 Pfam PF07155 ECF-type riboflavin transporter, S component 3 170 5.4E-37 T 14-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 C2I25_01190 0394b2755aa71c9e1476f7c123474635 159 Pfam PF00583 Acetyltransferase (GNAT) family 42 135 6.2E-14 T 14-10-2018 IPR000182 GNAT domain C2I25_01190 0394b2755aa71c9e1476f7c123474635 159 SUPERFAMILY SSF55729 1 147 3.66E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01190 0394b2755aa71c9e1476f7c123474635 159 Gene3D G3DSA:3.40.630.30 1 158 1.5E-39 T 14-10-2018 C2I25_24295 94262843cccf6d1adbc431616038fd81 132 SUPERFAMILY SSF89360 32 120 8.11E-5 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I25_24295 94262843cccf6d1adbc431616038fd81 132 Pfam PF01521 Iron-sulphur cluster biosynthesis 32 124 3.1E-7 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I25_13650 4b9bc276216896f5189016cef16ce0df 321 Gene3D G3DSA:2.40.128.540 49 180 8.5E-59 T 14-10-2018 C2I25_13650 4b9bc276216896f5189016cef16ce0df 321 Pfam PF16103 Domain of unknown function (DUF4822) 57 176 2.7E-53 T 14-10-2018 IPR032247 Domain of unknown function DUF4822 C2I25_13650 4b9bc276216896f5189016cef16ce0df 321 Pfam PF16103 Domain of unknown function (DUF4822) 197 319 5.1E-52 T 14-10-2018 IPR032247 Domain of unknown function DUF4822 C2I25_13650 4b9bc276216896f5189016cef16ce0df 321 Gene3D G3DSA:2.40.128.540 181 321 4.6E-62 T 14-10-2018 C2I25_03915 b93f9232f768436fb9c90080469fa89d 225 Gene3D G3DSA:3.40.50.300 1 221 2.9E-88 T 14-10-2018 C2I25_03915 b93f9232f768436fb9c90080469fa89d 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 217 5.1E-91 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 C2I25_03915 b93f9232f768436fb9c90080469fa89d 225 SUPERFAMILY SSF52540 6 222 2.19E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_03915 b93f9232f768436fb9c90080469fa89d 225 Pfam PF02224 Cytidylate kinase 7 219 1.8E-82 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 C2I25_03915 b93f9232f768436fb9c90080469fa89d 225 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 34.407 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 C2I25_07670 9575c7e9dbc2f0d00d4f8cf4efdf88f1 26 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 26 4.8E-8 T 14-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 C2I25_07670 9575c7e9dbc2f0d00d4f8cf4efdf88f1 26 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 3 26 7.0E-9 T 14-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 Gene3D G3DSA:3.40.720.10 45 446 3.5E-128 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 SUPERFAMILY SSF53649 28 475 1.3E-116 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 SMART SM00098 45 469 4.3E-84 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 Pfam PF00245 Alkaline phosphatase 45 466 6.2E-89 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 Gene3D G3DSA:1.10.1200.140 381 443 3.5E-128 T 14-10-2018 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 PRINTS PR00113 Alkaline phosphatase signature 263 292 3.8E-32 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 PRINTS PR00113 Alkaline phosphatase signature 186 196 3.8E-32 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 PRINTS PR00113 Alkaline phosphatase signature 44 64 3.8E-32 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_24565 f096093113bfe8ebf81a8b6f030328d9 557 PRINTS PR00113 Alkaline phosphatase signature 142 162 3.8E-32 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I25_02130 371a7555230ad5864ddad944908622bb 431 Pfam PF13687 Domain of unknown function (DUF4153) 231 390 3.1E-7 T 14-10-2018 IPR025291 Protein of unknown function DUF4153 C2I25_00410 445aa8a2b746603ccf3695372be46442 145 Pfam PF07179 SseB protein N-terminal domain 9 130 7.7E-15 T 14-10-2018 IPR009839 SseB protein N-terminal domain C2I25_06730 3c7a66373c3b6c16aa41e3adffeb9caf 108 SUPERFAMILY SSF101386 30 89 3.92E-7 T 14-10-2018 C2I25_00175 64b5fbc5d8def56eba5ec3d834e0eea7 215 SUPERFAMILY SSF55469 4 213 9.03E-50 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_00175 64b5fbc5d8def56eba5ec3d834e0eea7 215 Pfam PF00881 Nitroreductase family 10 193 8.1E-36 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I25_00175 64b5fbc5d8def56eba5ec3d834e0eea7 215 Gene3D G3DSA:3.40.109.10 4 214 1.3E-54 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I25_23305 292fde7fe82f36bcea22b64d9a5bc979 127 Pfam PF04434 SWIM zinc finger 51 82 4.8E-7 T 14-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 C2I25_21480 963c2e5a02fd20396339bfd6830a0782 49 Pfam PF08175 Small acid-soluble spore protein O family 3 49 1.9E-24 T 14-10-2018 C2I25_21480 963c2e5a02fd20396339bfd6830a0782 49 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 38 6.0E-14 T 14-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 C2I25_21480 963c2e5a02fd20396339bfd6830a0782 49 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 49 2.1E-29 T 14-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 C2I25_21480 963c2e5a02fd20396339bfd6830a0782 49 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 49 21.674 T 14-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 C2I25_24510 62655007e4c3dede4a72b7976cc6c12a 127 Pfam PF12681 Glyoxalase-like domain 5 127 6.5E-45 T 14-10-2018 IPR025870 Glyoxalase-like domain C2I25_24510 62655007e4c3dede4a72b7976cc6c12a 127 SUPERFAMILY SSF54593 4 124 1.07E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24510 62655007e4c3dede4a72b7976cc6c12a 127 Gene3D G3DSA:3.10.180.10 1 127 2.7E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24785 db25910cd58c330a5327b465eb4f8ab3 145 Pfam PF10710 Protein of unknown function (DUF2512) 3 135 8.0E-43 T 14-10-2018 IPR019649 Protein of unknown function DUF2512 C2I25_15685 1bdebf3c02b0d96dbf33aeb80f331071 60 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 59 6.0E-27 T 14-10-2018 IPR020296 Sporulation protein Cse60 C2I25_15685 1bdebf3c02b0d96dbf33aeb80f331071 60 Pfam PF10957 Sporulation protein Cse60 1 60 4.8E-35 T 14-10-2018 IPR020296 Sporulation protein Cse60 C2I25_03175 9ff077a6a7fb3c3d0d6bc0451d6bf355 432 SUPERFAMILY SSF64518 161 432 2.22E-15 T 14-10-2018 C2I25_03175 9ff077a6a7fb3c3d0d6bc0451d6bf355 432 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 5 428 9.8E-77 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 C2I25_03175 9ff077a6a7fb3c3d0d6bc0451d6bf355 432 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 383 427 2.6E-10 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I25_19560 4154d0541cad881f08f3fc545718c34d 172 Pfam PF04308 Ribonuclease H-like 20 172 3.2E-48 T 14-10-2018 IPR007405 Bacteriophage KVP40, Orf299 C2I25_16820 2e6ae901da38c2b8988ae367efcef3d9 428 Pfam PF00860 Permease family 10 391 2.6E-60 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I25_26910 764cd61038a673e896fbdd264f92e5e3 197 Pfam PF13222 Protein of unknown function (DUF4030) 54 195 1.8E-66 T 14-10-2018 IPR025108 Protein of unknown function DUF4030 C2I25_22245 da548b21dda79b6a5e677e089fe0cfd6 337 SUPERFAMILY SSF55909 1 333 1.12E-98 T 14-10-2018 C2I25_22245 da548b21dda79b6a5e677e089fe0cfd6 337 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 1 333 4.6E-91 T 14-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 C2I25_22245 da548b21dda79b6a5e677e089fe0cfd6 337 Gene3D G3DSA:3.75.10.10 1 337 1.8E-102 T 14-10-2018 C2I25_13665 63ea4514024d8bfb40ab899307039943 318 Pfam PF08378 Nuclease-related domain 39 154 2.5E-18 T 14-10-2018 IPR011528 Nuclease-related domain, NERD C2I25_01945 72080cd65f7e7a881cfc5a82457e78f4 182 Pfam PF16157 Domain of unknown function (DUF4865) 1 181 4.5E-67 T 14-10-2018 IPR032349 Protein of unknown function DUF4865 C2I25_19120 aed0779579709fc75e75736b1a5bd8ec 152 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 26 143 2.3E-41 T 14-10-2018 IPR005562 SpoVA C2I25_19120 aed0779579709fc75e75736b1a5bd8ec 152 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 9 147 3.2E-67 T 14-10-2018 IPR014203 Sporulation stage V, protein AC C2I25_16145 e2b6a99380baa67687f0948b26755525 401 Gene3D G3DSA:3.40.50.620 1 173 2.7E-65 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_16145 e2b6a99380baa67687f0948b26755525 401 Pfam PF00764 Arginosuccinate synthase 7 391 1.3E-179 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_16145 e2b6a99380baa67687f0948b26755525 401 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_16145 e2b6a99380baa67687f0948b26755525 401 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 396 54.381 T 14-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_16145 e2b6a99380baa67687f0948b26755525 401 SUPERFAMILY SSF52402 1 170 5.07E-47 T 14-10-2018 C2I25_16145 e2b6a99380baa67687f0948b26755525 401 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_16145 e2b6a99380baa67687f0948b26755525 401 SUPERFAMILY SSF69864 170 397 2.62E-95 T 14-10-2018 C2I25_16145 e2b6a99380baa67687f0948b26755525 401 Gene3D G3DSA:3.90.1260.10 174 401 1.3E-94 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_16145 e2b6a99380baa67687f0948b26755525 401 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 394 1.4E-173 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I25_20990 428544c4e8a6ea29e7c2131f9fadc3e0 207 Pfam PF03458 UPF0126 domain 92 160 3.9E-17 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 C2I25_20990 428544c4e8a6ea29e7c2131f9fadc3e0 207 Pfam PF03458 UPF0126 domain 5 78 1.4E-19 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 C2I25_15085 5a6719584c3b4f6b0516e173dde29292 323 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 11 319 7.7E-65 T 14-10-2018 IPR010106 Recombination-promoting nuclease RpnA C2I25_15085 5a6719584c3b4f6b0516e173dde29292 323 Pfam PF12784 PD-(D/E)XK nuclease family transposase 10 244 3.0E-64 T 14-10-2018 C2I25_18635 8d94e0e5960f43dd6d5eb7954d73f6c3 135 PIRSF PIRSF021328 1 135 2.5E-44 T 14-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 C2I25_18635 8d94e0e5960f43dd6d5eb7954d73f6c3 135 Pfam PF11208 Protein of unknown function (DUF2992) 3 135 1.5E-37 T 14-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 Pfam PF07690 Major Facilitator Superfamily 15 356 1.6E-54 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 PRINTS PR01035 Tetracycline resistance protein signature 77 101 4.0E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 PRINTS PR01035 Tetracycline resistance protein signature 340 363 4.0E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 PRINTS PR01035 Tetracycline resistance protein signature 20 36 4.0E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 PRINTS PR01035 Tetracycline resistance protein signature 135 157 4.0E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 PRINTS PR01035 Tetracycline resistance protein signature 163 183 4.0E-23 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 Gene3D G3DSA:1.20.1250.20 3 388 5.8E-68 T 14-10-2018 C2I25_23890 77ac98b7ff95e369f220488de883448d 404 SUPERFAMILY SSF103473 5 392 5.36E-70 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_21500 4760eaf8917b431b985b07a4a22c4b21 191 ProSitePatterns PS00194 Thioredoxin family active site. 80 98 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 C2I25_21500 4760eaf8917b431b985b07a4a22c4b21 191 SUPERFAMILY SSF52833 49 190 2.5E-46 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_21500 4760eaf8917b431b985b07a4a22c4b21 191 Gene3D G3DSA:3.40.30.10 20 191 5.3E-51 T 14-10-2018 C2I25_21500 4760eaf8917b431b985b07a4a22c4b21 191 Pfam PF00578 AhpC/TSA family 52 172 1.1E-34 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I25_01140 3a3954e7f9fc2b2bcbcab42bf6b7c35b 226 SUPERFAMILY SSF53335 10 195 1.96E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_01140 3a3954e7f9fc2b2bcbcab42bf6b7c35b 226 Pfam PF08241 Methyltransferase domain 52 144 2.1E-23 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_01140 3a3954e7f9fc2b2bcbcab42bf6b7c35b 226 Gene3D G3DSA:3.40.50.150 26 226 2.5E-64 T 14-10-2018 C2I25_13490 52c504d7736e7d2cd37ca0901add1562 338 SUPERFAMILY SSF53901 56 308 4.01E-16 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 C2I25_13490 52c504d7736e7d2cd37ca0901add1562 338 PIRSF PIRSF011570 1 335 3.7E-158 T 14-10-2018 IPR010894 Stage V sporulation AD C2I25_13490 52c504d7736e7d2cd37ca0901add1562 338 Gene3D G3DSA:3.40.47.40 1 338 6.1E-148 T 14-10-2018 IPR038369 Stage V sporulation AD superfamily C2I25_13490 52c504d7736e7d2cd37ca0901add1562 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 3.7E-156 T 14-10-2018 IPR010894 Stage V sporulation AD C2I25_13490 52c504d7736e7d2cd37ca0901add1562 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 2.0E-160 T 14-10-2018 IPR010894 Stage V sporulation AD C2I25_23815 05f2b95f6686e1f88f19113ea18af894 246 Pfam PF07423 Protein of unknown function (DUF1510) 5 244 3.2E-59 T 14-10-2018 IPR009988 Protein of unknown function DUF1510 C2I25_17365 3ccdf2ef776378070a902321a62a5676 309 Pfam PF01136 Peptidase family U32 75 306 1.8E-70 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 C2I25_08580 00d803c38e357edf2250d3bdacdfa47d 308 SUPERFAMILY SSF103481 192 297 5.95E-14 T 14-10-2018 C2I25_08580 00d803c38e357edf2250d3bdacdfa47d 308 SUPERFAMILY SSF103481 43 148 1.57E-8 T 14-10-2018 C2I25_08580 00d803c38e357edf2250d3bdacdfa47d 308 Pfam PF00892 EamA-like transporter family 7 146 3.1E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_08580 00d803c38e357edf2250d3bdacdfa47d 308 Pfam PF00892 EamA-like transporter family 159 293 2.3E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_05790 d5f4c837c4791e29cc9c0e913141471a 439 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 61 220 1.2E-21 T 14-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 C2I25_05790 d5f4c837c4791e29cc9c0e913141471a 439 Pfam PF01435 Peptidase family M48 225 431 4.0E-36 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 C2I25_05790 d5f4c837c4791e29cc9c0e913141471a 439 Gene3D G3DSA:3.30.2010.10 220 302 3.8E-25 T 14-10-2018 C2I25_19235 2de40813a20aae90d71eee025550d74b 125 Pfam PF13054 Protein of unknown function (DUF3915) 5 123 1.7E-61 T 14-10-2018 IPR025026 Protein of unknown function DUF3915 C2I25_21205 aff4be1e1fab97a9fdec56ee9e180d4d 195 Pfam PF13521 AAA domain 8 179 2.2E-12 T 14-10-2018 IPR038727 NadR/Ttd14, AAA domain C2I25_21205 aff4be1e1fab97a9fdec56ee9e180d4d 195 SUPERFAMILY SSF52540 5 189 8.89E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_21205 aff4be1e1fab97a9fdec56ee9e180d4d 195 Gene3D G3DSA:3.40.50.300 7 186 6.5E-12 T 14-10-2018 C2I25_02125 4e32491e7b891110eda1bdb29242206a 321 Pfam PF01758 Sodium Bile acid symporter family 38 223 1.2E-29 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 C2I25_02125 4e32491e7b891110eda1bdb29242206a 321 Gene3D G3DSA:1.20.1530.20 1 311 1.5E-42 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily C2I25_09285 fd6dc9b29b6245f2018ee9592d601f1a 543 Pfam PF14266 Putative component of 'biosynthetic module' 40 525 1.1E-162 T 14-10-2018 IPR025647 Putative component of 'biosynthetic module' C2I25_10060 45423c6955c389da4b11bcc080c10ea4 243 Gene3D G3DSA:3.40.30.10 1 209 1.6E-74 T 14-10-2018 C2I25_10060 45423c6955c389da4b11bcc080c10ea4 243 Pfam PF01323 DSBA-like thioredoxin domain 2 206 2.3E-42 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 C2I25_10060 45423c6955c389da4b11bcc080c10ea4 243 SUPERFAMILY SSF52833 1 212 3.19E-45 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_16130 ee1f22363c1959b38ebf1641039b12c0 220 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 199 3.3E-43 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_07665 266e928c69d04a27d30afb5aec889a2d 555 Pfam PF03814 Potassium-transporting ATPase A subunit 8 552 1.8E-227 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 C2I25_07665 266e928c69d04a27d30afb5aec889a2d 555 PIRSF PIRSF001294 1 555 7.4E-233 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 C2I25_07665 266e928c69d04a27d30afb5aec889a2d 555 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 3 554 5.5E-201 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 C2I25_07665 266e928c69d04a27d30afb5aec889a2d 555 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 554 32.379 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 C2I25_14645 c2893370abc5fc6f998569754e81cbe0 77 Pfam PF04070 Domain of unknown function (DUF378) 3 61 4.7E-26 T 14-10-2018 IPR007211 Protein of unknown function DUF378 C2I25_27785 3d76913d76e698bb2d84e5c339ca3545 434 TIGRFAM TIGR03721 exospore_TM: BclB C-terminal domain 271 434 1.2E-64 T 14-10-2018 IPR021210 Exosporium BclB, C-terminal C2I25_27785 3d76913d76e698bb2d84e5c339ca3545 434 Pfam PF01391 Collagen triple helix repeat (20 copies) 214 271 8.3E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_26065 e0199597ee292fb9857928e7b7bf3960 175 Pfam PF13302 Acetyltransferase (GNAT) domain 4 143 1.0E-17 T 14-10-2018 IPR000182 GNAT domain C2I25_26065 e0199597ee292fb9857928e7b7bf3960 175 SUPERFAMILY SSF55729 3 145 1.95E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26065 e0199597ee292fb9857928e7b7bf3960 175 Gene3D G3DSA:3.40.630.30 1 169 3.2E-25 T 14-10-2018 C2I25_02785 92c5849435be1501ee5d1a01f6203105 219 Pfam PF13578 Methyltransferase domain 45 161 1.1E-23 T 14-10-2018 C2I25_02785 92c5849435be1501ee5d1a01f6203105 219 Gene3D G3DSA:3.40.50.150 21 198 6.5E-19 T 14-10-2018 C2I25_02785 92c5849435be1501ee5d1a01f6203105 219 SUPERFAMILY SSF53335 25 192 1.04E-15 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_06745 0c14d8ea3acb9eec65196e7f443e6f1c 112 Pfam PF09685 Domain of unknown function (DUF4870) 14 101 5.3E-9 T 14-10-2018 IPR019109 Protein of unknown function DUF4870 C2I25_17565 f7494e3d6521a36c9d2f9b8d25e7de14 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 5.6E-21 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17565 f7494e3d6521a36c9d2f9b8d25e7de14 49 Pfam PF00471 Ribosomal protein L33 3 49 3.6E-23 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17565 f7494e3d6521a36c9d2f9b8d25e7de14 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I25_17565 f7494e3d6521a36c9d2f9b8d25e7de14 49 SUPERFAMILY SSF57829 1 49 1.83E-19 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 C2I25_17565 f7494e3d6521a36c9d2f9b8d25e7de14 49 Gene3D G3DSA:2.20.28.120 1 49 1.3E-24 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_17565 f7494e3d6521a36c9d2f9b8d25e7de14 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.619 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I25_25170 45e0b7f1674b1b7fe7085f07cd480bca 207 Pfam PF13171 Protein of unknown function (DUF4004) 4 199 7.2E-86 T 14-10-2018 IPR025063 Protein of unknown function DUF4004 C2I25_10815 9afb5d25518cc761f7ad38b0d8249bb9 264 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 1 264 36.66 T 14-10-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 C2I25_10815 9afb5d25518cc761f7ad38b0d8249bb9 264 Pfam PF02361 Cobalt transport protein 13 235 6.1E-58 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component C2I25_00750 08121e29a6f1ee59dbf79df9e70683dc 282 Pfam PF10668 Phage terminase small subunit 1 64 5.1E-22 T 14-10-2018 IPR018925 Phage terminase small subunit C2I25_02530 42c4c4ffbb72a1fbd2f2cfa49e22a087 267 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 17 236 5.5E-87 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related C2I25_02530 42c4c4ffbb72a1fbd2f2cfa49e22a087 267 PIRSF PIRSF028756 2 264 1.8E-78 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 C2I25_02530 42c4c4ffbb72a1fbd2f2cfa49e22a087 267 Gene3D G3DSA:3.40.50.300 1 239 5.5E-100 T 14-10-2018 C2I25_02530 42c4c4ffbb72a1fbd2f2cfa49e22a087 267 SUPERFAMILY SSF52540 48 241 2.34E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_09960 52eb726fb00b40f349a9692370f64963 263 Pfam PF03567 Sulfotransferase family 23 258 9.9E-11 T 14-10-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 C2I25_01820 3e9e5aff1853c6427c7a5ecdf0722079 197 Pfam PF11337 Protein of unknown function (DUF3139) 6 87 8.5E-15 T 14-10-2018 IPR021486 Protein of unknown function DUF3139 C2I25_20215 88b9a2b59d0bfaf1854e4c847f637a04 26 Pfam PF08183 Stage V sporulation protein family 1 25 2.1E-17 T 14-10-2018 IPR012609 Sporulation stage V, protein M C2I25_17325 d5e218b186fdbd69d7a855fd54495380 355 Pfam PF01594 AI-2E family transporter 33 345 1.1E-67 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like C2I25_07345 5de39064904df04af5e6f479a645da55 392 Pfam PF12704 MacB-like periplasmic core domain 21 230 2.9E-23 T 14-10-2018 IPR025857 MacB-like periplasmic core domain C2I25_07345 5de39064904df04af5e6f479a645da55 392 Pfam PF02687 FtsX-like permease family 298 381 6.7E-10 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_15280 80c8dd6c2db0caf46a1f245e2b692c12 178 Pfam PF11667 Putative zincin peptidase 58 163 9.4E-22 T 14-10-2018 IPR021683 Putative zincin peptidase C2I25_09325 d6e1ac69959b0b3044d808f82fb735b8 103 Pfam PF14150 YesK-like protein 16 96 4.3E-32 T 14-10-2018 IPR025434 YesK-like protein C2I25_02775 5c68e4eaca83349acecf9644f6e21a28 126 Gene3D G3DSA:1.10.1660.10 1 117 8.7E-37 T 14-10-2018 C2I25_02775 5c68e4eaca83349acecf9644f6e21a28 126 SUPERFAMILY SSF46955 3 120 1.61E-29 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I25_02775 5c68e4eaca83349acecf9644f6e21a28 126 Pfam PF13411 MerR HTH family regulatory protein 3 69 4.6E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_02775 5c68e4eaca83349acecf9644f6e21a28 126 SMART SM00422 3 72 2.4E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I25_05330 039341433b7fcde88e87259a13a84796 226 Gene3D G3DSA:3.90.550.10 6 226 3.0E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_05330 039341433b7fcde88e87259a13a84796 226 SUPERFAMILY SSF53448 19 221 7.16E-10 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I25_05330 039341433b7fcde88e87259a13a84796 226 Pfam PF13712 Glycosyltransferase like family 8 219 1.2E-82 T 14-10-2018 C2I25_04065 a976363c2a814447523a0a109bc1f3a2 163 Pfam PF13047 Protein of unknown function (DUF3907) 10 157 7.7E-63 T 14-10-2018 IPR025013 Protein of unknown function DUF3907 C2I25_22180 9c65eb6b423340bb5a5505e5fc79497e 199 Gene3D G3DSA:2.30.110.10 1 199 2.0E-74 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I25_22180 9c65eb6b423340bb5a5505e5fc79497e 199 SUPERFAMILY SSF50475 11 181 2.5E-36 T 14-10-2018 C2I25_22180 9c65eb6b423340bb5a5505e5fc79497e 199 Pfam PF04299 Putative FMN-binding domain 1 158 9.7E-53 T 14-10-2018 IPR007396 Transcriptional regulator PAI 2-type C2I25_22180 9c65eb6b423340bb5a5505e5fc79497e 199 PIRSF PIRSF010372 1 199 6.5E-65 T 14-10-2018 IPR007396 Transcriptional regulator PAI 2-type C2I25_05350 e1ab75ad777eb1755f79b2edc3bd344e 292 Pfam PF01391 Collagen triple helix repeat (20 copies) 41 97 4.3E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_05350 e1ab75ad777eb1755f79b2edc3bd344e 292 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 21 39 1.4E-8 T 14-10-2018 IPR021201 Leader peptide, exosporium C2I25_05350 e1ab75ad777eb1755f79b2edc3bd344e 292 Gene3D G3DSA:2.60.120.40 158 292 6.1E-60 T 14-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I25_12790 dafe5b8114f7d0b693b329bd512f49be 144 Pfam PF07977 FabA-like domain 11 134 7.2E-35 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I25_12790 dafe5b8114f7d0b693b329bd512f49be 144 Gene3D G3DSA:3.10.129.10 1 144 3.3E-59 T 14-10-2018 C2I25_12790 dafe5b8114f7d0b693b329bd512f49be 144 SUPERFAMILY SSF54637 1 139 6.71E-48 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_12790 dafe5b8114f7d0b693b329bd512f49be 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 139 9.2E-58 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I25_12790 dafe5b8114f7d0b693b329bd512f49be 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 34.67 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I25_26950 d4ed51242467e3726e17950303c5a37e 112 SUPERFAMILY SSF46785 9 107 4.4E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_26950 d4ed51242467e3726e17950303c5a37e 112 Gene3D G3DSA:1.10.10.10 5 112 1.0E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_26950 d4ed51242467e3726e17950303c5a37e 112 Pfam PF01638 HxlR-like helix-turn-helix 17 105 4.0E-34 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_07165 8e643673839a0a7db11e9feabe73aa67 114 Gene3D G3DSA:1.10.3730.20 3 108 5.8E-19 T 14-10-2018 C2I25_07165 8e643673839a0a7db11e9feabe73aa67 114 Pfam PF00893 Small Multidrug Resistance protein 5 93 2.8E-15 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I25_07165 8e643673839a0a7db11e9feabe73aa67 114 SUPERFAMILY SSF103481 8 105 1.83E-12 T 14-10-2018 C2I25_22350 a704b0cf31108b8fb786d3bbd03d0314 254 PIRSF PIRSF009141 1 254 5.1E-127 T 14-10-2018 IPR008535 Protein of unknown function DUF817 C2I25_22350 a704b0cf31108b8fb786d3bbd03d0314 254 Pfam PF05675 Protein of unknown function (DUF817) 6 240 2.5E-104 T 14-10-2018 IPR008535 Protein of unknown function DUF817 C2I25_21870 472674de4ce16e6811f0a017626b0698 206 Pfam PF01184 GPR1/FUN34/yaaH family 8 197 3.2E-23 T 14-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 C2I25_03250 6061c0990d415a5a6aee67fdc173d1ad 39 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 7 30 8.7E-11 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_03250 6061c0990d415a5a6aee67fdc173d1ad 39 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 9 32 2.0E-11 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_09010 b72444a4a58f06b2746d933725ca96ec 105 Pfam PF08838 Protein of unknown function (DUF1811) 5 103 2.7E-40 T 14-10-2018 IPR014938 Protein of unknown function DUF1811 C2I25_09010 b72444a4a58f06b2746d933725ca96ec 105 Gene3D G3DSA:1.10.287.880 1 52 4.4E-25 T 14-10-2018 C2I25_09010 b72444a4a58f06b2746d933725ca96ec 105 SUPERFAMILY SSF101697 3 105 3.01E-45 T 14-10-2018 IPR036289 Hypothetical protein YfhH C2I25_09010 b72444a4a58f06b2746d933725ca96ec 105 Gene3D G3DSA:2.30.30.340 54 105 1.3E-19 T 14-10-2018 C2I25_02955 e9992cd546b5812a9146c305cd282150 111 Gene3D G3DSA:3.30.70.100 9 101 4.0E-37 T 14-10-2018 C2I25_02955 e9992cd546b5812a9146c305cd282150 111 SUPERFAMILY SSF54909 7 106 6.34E-30 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_02955 e9992cd546b5812a9146c305cd282150 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 30 83 3.9E-7 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I25_06580 30988d64ab8b0bb80c9024dfdbfa56cc 123 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 27 123 4.0E-49 T 14-10-2018 C2I25_06580 30988d64ab8b0bb80c9024dfdbfa56cc 123 Pfam PF03899 ATP synthase I chain 10 103 4.3E-13 T 14-10-2018 IPR005598 ATP synthase protein I C2I25_26170 f561be165efa74ad165f7476decafd74 338 Pfam PF00144 Beta-lactamase 10 316 1.7E-34 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_26170 f561be165efa74ad165f7476decafd74 338 Gene3D G3DSA:3.40.710.10 3 317 5.4E-50 T 14-10-2018 C2I25_26170 f561be165efa74ad165f7476decafd74 338 SUPERFAMILY SSF56601 4 320 3.08E-52 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_03040 0bd5c29327b8e56ae90f9879a2a5c5ca 119 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 27 102 3.8E-25 T 14-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 C2I25_03040 0bd5c29327b8e56ae90f9879a2a5c5ca 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 76 91 1.1E-10 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03040 0bd5c29327b8e56ae90f9879a2a5c5ca 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 63 76 1.1E-10 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03040 0bd5c29327b8e56ae90f9879a2a5c5ca 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 47 63 1.1E-10 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03040 0bd5c29327b8e56ae90f9879a2a5c5ca 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 30 46 1.1E-10 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I25_03040 0bd5c29327b8e56ae90f9879a2a5c5ca 119 SUPERFAMILY SSF101801 27 103 3.79E-17 T 14-10-2018 IPR036429 SpoA-like superfamily C2I25_03040 0bd5c29327b8e56ae90f9879a2a5c5ca 119 Gene3D G3DSA:2.30.330.10 17 110 1.3E-18 T 14-10-2018 IPR036429 SpoA-like superfamily C2I25_03040 0bd5c29327b8e56ae90f9879a2a5c5ca 119 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 30 99 9.9E-17 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) C2I25_13065 df45a010affd930d3012ec12298d6fd6 163 Pfam PF09988 Uncharacterized metal-binding protein (DUF2227) 2 154 3.8E-44 T 14-10-2018 IPR019250 Protein of unknown function DUF2227, metal-binding C2I25_09220 545d4ff8b00db15ec722dcc5b4f1bf4e 197 Pfam PF09335 SNARE associated Golgi protein 30 156 3.9E-18 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_11390 8c95854731a409f81e43fd5b363566dd 59 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_11390 8c95854731a409f81e43fd5b363566dd 59 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 54 3.8E-7 T 14-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I25_02750 6584464ad91c1d7e9e5c31f7bdedd40e 254 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 185 252 1.9E-28 T 14-10-2018 IPR018656 Domain of unknown function DUF2087 C2I25_28090 4e3c12a90ed6b1d4aa7d94eaa9ac2320 206 SUPERFAMILY SSF54909 107 173 2.23E-9 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_28090 4e3c12a90ed6b1d4aa7d94eaa9ac2320 206 Gene3D G3DSA:3.30.70.100 40 175 3.3E-10 T 14-10-2018 C2I25_28090 4e3c12a90ed6b1d4aa7d94eaa9ac2320 206 SUPERFAMILY SSF54909 1 93 2.82E-14 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_28090 4e3c12a90ed6b1d4aa7d94eaa9ac2320 206 Pfam PF16291 Domain of unknown function (DUF4937 2 87 1.6E-34 T 14-10-2018 IPR032555 Domain of unknown function DUF4937 C2I25_09515 7da549a99bc9f3b119c7754dafe88452 230 SUPERFAMILY SSF161098 10 212 3.27E-45 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_09515 7da549a99bc9f3b119c7754dafe88452 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 105 5.6E-26 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I25_09515 7da549a99bc9f3b119c7754dafe88452 230 Gene3D G3DSA:1.10.3720.10 1 215 7.0E-55 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_09515 7da549a99bc9f3b119c7754dafe88452 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 211 1.6E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_18505 1ad75d8de6f7c5118d6d54a0a10135fc 412 Gene3D G3DSA:1.20.1270.210 36 301 5.4E-20 T 14-10-2018 C2I25_18505 1ad75d8de6f7c5118d6d54a0a10135fc 412 Gene3D G3DSA:3.30.1120.70 196 247 5.4E-20 T 14-10-2018 C2I25_18505 1ad75d8de6f7c5118d6d54a0a10135fc 412 Pfam PF04860 Phage portal protein 43 362 2.9E-64 T 14-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein C2I25_18505 1ad75d8de6f7c5118d6d54a0a10135fc 412 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 34 367 1.9E-59 T 14-10-2018 IPR006427 Phage portal protein, HK97 C2I25_18505 1ad75d8de6f7c5118d6d54a0a10135fc 412 Gene3D G3DSA:2.40.500.30 59 308 5.4E-20 T 14-10-2018 C2I25_06770 23c21999d45503c0c2baac1f398012e9 788 Pfam PF13643 Domain of unknown function (DUF4145) 23 105 4.4E-5 T 14-10-2018 IPR025285 Domain of unknown function DUF4145 C2I25_06770 23c21999d45503c0c2baac1f398012e9 788 TIGRFAM TIGR03238 dnd_assoc_3: DNA phosphorothioation-dependent restriction protein DptF 245 787 1.0E-102 T 14-10-2018 IPR017647 DNA phosphorothioation-dependent restriction protein DptF C2I25_26695 02f97cd28d53b2df42df59449189e11e 55 Pfam PF13128 Protein of unknown function (DUF3954) 3 51 4.0E-21 T 14-10-2018 IPR025017 Protein of unknown function DUF3954 C2I25_12290 9cb54e229e77816aaf81babca9f5f366 169 Pfam PF08741 YwhD family 5 166 1.3E-85 T 14-10-2018 IPR014852 Uncharacterised protein YwhD C2I25_22220 c1c87653b2f7ca4bdafc0522301b4bbc 169 Pfam PF13079 Protein of unknown function (DUF3916) 17 167 4.8E-65 T 14-10-2018 IPR025075 Protein of unknown function DUF3916 C2I25_19315 3217600de36bb959d595ecb12f63e56a 53 Pfam PF12841 YvrJ protein family 7 41 1.1E-17 T 14-10-2018 IPR024419 Protein of unknown function YvrJ C2I25_24595 79baf34c5336b5bb4059cbbfcdad899b 115 Gene3D G3DSA:3.10.180.10 8 115 7.2E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_24595 79baf34c5336b5bb4059cbbfcdad899b 115 SUPERFAMILY SSF54593 6 114 2.68E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_27645 f4299ec861344c269efd977529d71632 420 Pfam PF07690 Major Facilitator Superfamily 23 377 2.2E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_27645 f4299ec861344c269efd977529d71632 420 SUPERFAMILY SSF103473 18 411 2.75E-39 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_27645 f4299ec861344c269efd977529d71632 420 Gene3D G3DSA:1.20.1250.20 13 413 1.2E-39 T 14-10-2018 C2I25_12040 ffe3897c008c4a73f211bffd5e26550e 214 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 57 162 1.2E-9 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like C2I25_19715 22ffb478814c01dc918bef84b3d20ff2 100 Pfam PF14036 YlaH-like protein 16 91 1.3E-32 T 14-10-2018 IPR025620 YlaH-like protein C2I25_12835 4baccd5fc973883446c83b751b283431 301 SUPERFAMILY SSF51735 1 287 1.24E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_12835 4baccd5fc973883446c83b751b283431 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 223 1.5E-35 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_12835 4baccd5fc973883446c83b751b283431 301 Gene3D G3DSA:3.40.50.720 1 293 6.5E-83 T 14-10-2018 C2I25_09510 33a861b808975cb9981e2780d90a6eea 264 SMART SM00079 37 254 7.8E-4 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 C2I25_09510 33a861b808975cb9981e2780d90a6eea 264 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site C2I25_09510 33a861b808975cb9981e2780d90a6eea 264 Gene3D G3DSA:3.40.190.10 36 252 4.9E-71 T 14-10-2018 C2I25_09510 33a861b808975cb9981e2780d90a6eea 264 SMART SM00062 37 255 2.4E-69 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_09510 33a861b808975cb9981e2780d90a6eea 264 SUPERFAMILY SSF53850 1 255 2.25E-70 T 14-10-2018 C2I25_09510 33a861b808975cb9981e2780d90a6eea 264 Gene3D G3DSA:3.40.190.10 121 217 4.9E-71 T 14-10-2018 C2I25_09510 33a861b808975cb9981e2780d90a6eea 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 253 3.9E-68 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I25_15575 4483ddd7f07a65250126d02080b8fb32 361 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 9 360 1.9E-93 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_15575 4483ddd7f07a65250126d02080b8fb32 361 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 199 358 2.1E-28 T 14-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I25_15575 4483ddd7f07a65250126d02080b8fb32 361 Gene3D G3DSA:3.30.300.210 216 361 1.4E-18 T 14-10-2018 IPR038501 Spore germination GerAC superfamily C2I25_00995 24e96a196a7d7bdae73a3ca585f1bea3 305 Pfam PF03547 Membrane transport protein 161 297 2.8E-12 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I25_21925 d75ea1a1aa362b9c7b029ebde1b8c35d 225 Pfam PF02308 MgtC family 12 138 1.7E-37 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_21925 d75ea1a1aa362b9c7b029ebde1b8c35d 225 PRINTS PR01837 MgtC/SapB protein signature 94 118 5.2E-48 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_21925 d75ea1a1aa362b9c7b029ebde1b8c35d 225 PRINTS PR01837 MgtC/SapB protein signature 14 33 5.2E-48 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_21925 d75ea1a1aa362b9c7b029ebde1b8c35d 225 PRINTS PR01837 MgtC/SapB protein signature 67 89 5.2E-48 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_21925 d75ea1a1aa362b9c7b029ebde1b8c35d 225 PRINTS PR01837 MgtC/SapB protein signature 33 51 5.2E-48 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I25_06070 ba9c6dd8dec454dd619a02125b4864ca 158 Pfam PF03703 Bacterial PH domain 72 147 6.3E-17 T 14-10-2018 IPR005182 Domain of unknown function DUF304 C2I25_26060 a2a7febf70fa2d950107d9317b9afd31 439 Pfam PF01494 FAD binding domain 151 339 4.2E-5 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 C2I25_26060 a2a7febf70fa2d950107d9317b9afd31 439 SUPERFAMILY SSF51905 4 351 7.79E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_26060 a2a7febf70fa2d950107d9317b9afd31 439 Gene3D G3DSA:3.50.50.60 4 411 2.1E-15 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_17685 5c032b183809b61a6efa59f0264ef2af 124 SUPERFAMILY SSF46785 16 119 1.52E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_17685 5c032b183809b61a6efa59f0264ef2af 124 Pfam PF01638 HxlR-like helix-turn-helix 28 117 2.0E-33 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_17685 5c032b183809b61a6efa59f0264ef2af 124 Gene3D G3DSA:1.10.10.10 3 124 5.7E-39 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_00285 72df8567b64fb5b7a3706f6bc6ab599c 310 Pfam PF01636 Phosphotransferase enzyme family 20 243 3.9E-22 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_00285 72df8567b64fb5b7a3706f6bc6ab599c 310 SUPERFAMILY SSF56112 20 260 1.9E-35 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_00285 72df8567b64fb5b7a3706f6bc6ab599c 310 Gene3D G3DSA:3.90.1200.10 100 289 2.1E-22 T 14-10-2018 C2I25_14240 30b48697800e9f5ded0fa3734cc33a29 159 SUPERFAMILY SSF55826 2 144 2.35E-33 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I25_14240 30b48697800e9f5ded0fa3734cc33a29 159 Pfam PF04073 Aminoacyl-tRNA editing domain 44 142 1.3E-20 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 C2I25_14240 30b48697800e9f5ded0fa3734cc33a29 159 Gene3D G3DSA:3.90.960.10 1 155 3.5E-31 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I25_26935 47dcfca2729b8bafbcf38c16728594dc 264 Gene3D G3DSA:3.10.180.10 3 219 2.0E-35 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_26935 47dcfca2729b8bafbcf38c16728594dc 264 SUPERFAMILY SSF54593 2 118 3.44E-10 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_04205 7eff8674d97d37a0e104902e8293eec9 87 Pfam PF13059 Protein of unknown function (DUF3992) 7 85 1.8E-52 T 14-10-2018 IPR025035 Protein of unknown function DUF3922 C2I25_09565 a8de545aa3d64e6f2639502a52ba4b0b 222 ProDom PD210561 YWRJ 1 222 1.0E-125 T 14-10-2018 IPR020173 Uncharacterised protein family YwrJ C2I25_14125 73e45ddfb5f92a5b43278c9fdac6ccf1 87 Pfam PF13780 Domain of unknown function (DUF4176) 9 81 2.3E-29 T 14-10-2018 IPR025233 Protein of unknown function DUF4176 C2I25_24760 b8be5be5f1eb7e7f477c75f55039ff92 174 Gene3D G3DSA:3.40.50.300 8 173 4.4E-17 T 14-10-2018 C2I25_24760 b8be5be5f1eb7e7f477c75f55039ff92 174 Pfam PF13671 AAA domain 10 124 1.6E-6 T 14-10-2018 C2I25_24760 b8be5be5f1eb7e7f477c75f55039ff92 174 SUPERFAMILY SSF52540 9 149 8.67E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_16965 18ae544061ccdb5a90430635f0209bc8 250 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 243 2.5E-60 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_16965 18ae544061ccdb5a90430635f0209bc8 250 Gene3D G3DSA:3.40.50.10090 144 249 3.4E-22 T 14-10-2018 C2I25_16965 18ae544061ccdb5a90430635f0209bc8 250 Gene3D G3DSA:3.40.50.10090 3 125 4.9E-24 T 14-10-2018 C2I25_16965 18ae544061ccdb5a90430635f0209bc8 250 SUPERFAMILY SSF69618 6 247 4.71E-60 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I25_17425 340b45b3a252792496c672dd3fba95af 75 Pfam PF14143 YrhC-like protein 2 73 1.3E-26 T 14-10-2018 IPR025418 YrhC-like protein C2I25_13625 f868e4c571182ba22b46d87758ff8898 250 SMART SM00382 26 213 1.0E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_13625 f868e4c571182ba22b46d87758ff8898 250 SUPERFAMILY SSF52540 2 226 4.99E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13625 f868e4c571182ba22b46d87758ff8898 250 Gene3D G3DSA:3.40.50.300 1 243 2.4E-59 T 14-10-2018 C2I25_13625 f868e4c571182ba22b46d87758ff8898 250 Pfam PF00005 ABC transporter 21 164 9.1E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_21210 c170095bb04ed1d27613fce52d106f66 190 Pfam PF01965 DJ-1/PfpI family 2 155 8.4E-29 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I25_21210 c170095bb04ed1d27613fce52d106f66 190 SUPERFAMILY SSF52317 1 163 1.92E-33 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_21210 c170095bb04ed1d27613fce52d106f66 190 Gene3D G3DSA:3.40.50.880 1 181 9.5E-40 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_28365 5f77dd96128ba0b4b78c8745921879cc 178 Gene3D G3DSA:2.60.120.40 35 171 1.3E-10 T 14-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I25_28365 5f77dd96128ba0b4b78c8745921879cc 178 Pfam PF00386 C1q domain 39 152 6.8E-6 T 14-10-2018 IPR001073 C1q domain C2I25_28365 5f77dd96128ba0b4b78c8745921879cc 178 SUPERFAMILY SSF49842 38 170 9.94E-20 T 14-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I25_03110 d286acc58982935a2c7dd127879b9eb4 375 Gene3D G3DSA:3.30.750.140 241 356 1.9E-9 T 14-10-2018 IPR038610 FliK-like, C-terminal domain superfamily C2I25_03110 d286acc58982935a2c7dd127879b9eb4 375 Pfam PF02120 Flagellar hook-length control protein FliK 271 341 2.1E-8 T 14-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal C2I25_25050 be6c9c4e577c39879514be6911daaf98 223 Pfam PF13261 Protein of unknown function (DUF4052) 4 220 5.9E-122 T 14-10-2018 IPR025126 Protein of unknown function DUF4052 C2I25_06085 7f8395856f4210bf0b1f074007a31520 250 Pfam PF10014 2OG-Fe dioxygenase 55 243 2.2E-38 T 14-10-2018 IPR018724 2OG-Fe dioxygenase C2I25_06085 7f8395856f4210bf0b1f074007a31520 250 Gene3D G3DSA:2.60.120.620 13 249 1.0E-30 T 14-10-2018 C2I25_02835 442a77a64e4180b93fa424400f4b7b7e 357 SUPERFAMILY SSF110296 27 334 1.7E-44 T 14-10-2018 C2I25_02835 442a77a64e4180b93fa424400f4b7b7e 357 Gene3D G3DSA:2.130.10.10 77 341 3.1E-47 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I25_09605 a20779f4d2564d90984e6708d94d826a 305 Gene3D G3DSA:3.40.50.1980 48 136 3.0E-25 T 14-10-2018 C2I25_09605 a20779f4d2564d90984e6708d94d826a 305 Pfam PF01497 Periplasmic binding protein 70 278 1.8E-29 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_09605 a20779f4d2564d90984e6708d94d826a 305 SUPERFAMILY SSF53807 38 298 3.92E-53 T 14-10-2018 C2I25_09605 a20779f4d2564d90984e6708d94d826a 305 Gene3D G3DSA:3.40.50.1980 137 305 2.0E-58 T 14-10-2018 C2I25_00800 ae548b5a51f9c041af5ce047d58cc61a 190 Pfam PF07883 Cupin domain 94 169 1.5E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel C2I25_00800 ae548b5a51f9c041af5ce047d58cc61a 190 SUPERFAMILY SSF51182 34 175 4.74E-25 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I25_00800 ae548b5a51f9c041af5ce047d58cc61a 190 Gene3D G3DSA:2.60.120.10 69 190 3.5E-41 T 14-10-2018 IPR014710 RmlC-like jelly roll fold C2I25_20110 d3773421b5ab8ae5401666a069f2b3a4 122 Pfam PF14037 YoqO-like protein 4 118 3.3E-47 T 14-10-2018 IPR025621 YoqO-like protein C2I25_04820 2addfaec498fb4ccd997fef7f7719bfe 113 Pfam PF13045 Protein of unknown function (DUF3905) 11 93 7.5E-48 T 14-10-2018 IPR024999 Protein of unknown function DUF3905 C2I25_08710 0a8e613cca6f173959dd61a3dd3ddc2a 182 Gene3D G3DSA:2.40.50.140 95 174 1.4E-21 T 14-10-2018 C2I25_25595 3e0218a824aa29f69a6192cd47237200 226 Gene3D G3DSA:3.90.1580.10 5 225 1.0E-66 T 14-10-2018 C2I25_25595 3e0218a824aa29f69a6192cd47237200 226 SUPERFAMILY SSF56436 13 225 3.06E-54 T 14-10-2018 IPR016187 C-type lectin fold C2I25_25595 3e0218a824aa29f69a6192cd47237200 226 Pfam PF03781 Sulfatase-modifying factor enzyme 1 13 224 2.7E-39 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 C2I25_14030 b8e0a8cfcf766261797af27b05d91687 305 SUPERFAMILY SSF51730 37 300 3.57E-79 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like C2I25_14030 b8e0a8cfcf766261797af27b05d91687 305 Pfam PF01619 Proline dehydrogenase 45 298 5.1E-38 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 C2I25_14030 b8e0a8cfcf766261797af27b05d91687 305 PIRSF PIRSF000196 1 305 2.5E-137 T 14-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 C2I25_14030 b8e0a8cfcf766261797af27b05d91687 305 Gene3D G3DSA:3.20.20.530 19 305 2.7E-100 T 14-10-2018 C2I25_11440 bcea51051ebe7310423c31ad22fa8a26 246 Gene3D G3DSA:3.40.50.150 7 246 1.9E-71 T 14-10-2018 C2I25_11440 bcea51051ebe7310423c31ad22fa8a26 246 SUPERFAMILY SSF53335 13 198 6.08E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_11440 bcea51051ebe7310423c31ad22fa8a26 246 Pfam PF05175 Methyltransferase small domain 33 143 8.9E-8 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 C2I25_19370 c401720bb1d0edb14d1147a084549b08 242 Pfam PF13803 Domain of unknown function (DUF4184) 1 236 1.2E-74 T 14-10-2018 IPR025238 Protein of unknown function DUF4184 C2I25_15235 8f4d5185d63403ba7f6ce93294324110 231 Pfam PF00893 Small Multidrug Resistance protein 129 214 1.5E-20 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I25_15235 8f4d5185d63403ba7f6ce93294324110 231 Gene3D G3DSA:1.10.3730.20 127 229 3.6E-20 T 14-10-2018 C2I25_15235 8f4d5185d63403ba7f6ce93294324110 231 SUPERFAMILY SSF103481 132 225 1.44E-11 T 14-10-2018 C2I25_10375 9a71ede2385b951362191a320050e3f8 318 SUPERFAMILY SSF161098 89 304 4.97E-16 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10375 9a71ede2385b951362191a320050e3f8 318 Gene3D G3DSA:1.10.3720.10 83 311 1.8E-19 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_10375 9a71ede2385b951362191a320050e3f8 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 316 4.7E-41 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_17885 3b2d156b81c6462e3cd7ac4e8c12dcdd 137 Gene3D G3DSA:1.10.10.10 1 83 2.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17885 3b2d156b81c6462e3cd7ac4e8c12dcdd 137 SUPERFAMILY SSF46785 5 133 8.71E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_17885 3b2d156b81c6462e3cd7ac4e8c12dcdd 137 Pfam PF01475 Ferric uptake regulator family 12 129 3.4E-28 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 C2I25_17885 3b2d156b81c6462e3cd7ac4e8c12dcdd 137 Gene3D G3DSA:3.30.1490.190 87 137 3.0E-14 T 14-10-2018 C2I25_24330 6534aa6477d558fa09baf357b75426ba 180 SUPERFAMILY SSF81301 20 180 4.58E-39 T 14-10-2018 C2I25_24330 6534aa6477d558fa09baf357b75426ba 180 Gene3D G3DSA:3.30.460.10 14 180 8.1E-45 T 14-10-2018 C2I25_24330 6534aa6477d558fa09baf357b75426ba 180 Pfam PF04229 GrpB protein 18 180 7.3E-43 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase C2I25_12280 0fa20371b0cadb220649bb6efea18fe0 61 Pfam PF01361 Tautomerase enzyme 2 60 8.3E-25 T 14-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 C2I25_12280 0fa20371b0cadb220649bb6efea18fe0 61 Gene3D G3DSA:3.30.429.10 1 60 3.4E-28 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_12280 0fa20371b0cadb220649bb6efea18fe0 61 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 2.3E-27 T 14-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 C2I25_12280 0fa20371b0cadb220649bb6efea18fe0 61 SUPERFAMILY SSF55331 2 60 3.93E-20 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily C2I25_09065 ced5e950445b95b47d4b39323c494e9e 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 242 6.2E-60 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_09065 ced5e950445b95b47d4b39323c494e9e 321 Gene3D G3DSA:3.40.50.720 2 320 2.8E-100 T 14-10-2018 C2I25_09065 ced5e950445b95b47d4b39323c494e9e 321 SUPERFAMILY SSF51735 1 318 2.8E-84 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_24340 d218513dc6c5dba7af58cad01d060e57 104 Pfam PF13031 Protein of unknown function (DUF3892) 35 102 7.6E-17 T 14-10-2018 IPR024997 Protein of unknown function DUF3892 C2I25_06355 eea89cac08eeb05b418c6589b7e9ad3d 61 Pfam PF14120 YhzD-like protein 1 61 6.9E-26 T 14-10-2018 IPR025544 YhzD-like protein C2I25_21650 8be7cb37fd2a65493913fcb6989c8da6 239 SUPERFAMILY SSF53335 12 218 1.52E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_21650 8be7cb37fd2a65493913fcb6989c8da6 239 Gene3D G3DSA:3.40.50.150 2 221 8.9E-36 T 14-10-2018 C2I25_21650 8be7cb37fd2a65493913fcb6989c8da6 239 Pfam PF13649 Methyltransferase domain 41 133 5.6E-17 T 14-10-2018 C2I25_22345 32b0d17c0225dd2dc6ad4f630cf88a2b 328 Pfam PF13170 Protein of unknown function (DUF4003) 15 308 2.0E-101 T 14-10-2018 IPR025062 Protein of unknown function DUF4003 C2I25_13100 e0b2f4d5fcbc1debf590035a878e8d88 121 Pfam PF01610 Transposase 14 111 1.1E-10 T 14-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain C2I25_17460 2803a375aba25fba1788a451fb548891 168 Pfam PF13302 Acetyltransferase (GNAT) domain 6 146 3.4E-29 T 14-10-2018 IPR000182 GNAT domain C2I25_17460 2803a375aba25fba1788a451fb548891 168 Gene3D G3DSA:3.40.630.30 1 168 6.5E-40 T 14-10-2018 C2I25_17460 2803a375aba25fba1788a451fb548891 168 SUPERFAMILY SSF55729 2 151 4.1E-35 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_22375 94517ada10e57444b690d00ccefff5e3 75 Pfam PF01166 TSC-22/dip/bun family 9 42 1.6E-6 T 14-10-2018 IPR000580 TSC-22 / Dip / Bun GO:0003700|GO:0006355 C2I25_22375 94517ada10e57444b690d00ccefff5e3 75 SUPERFAMILY SSF58026 9 40 3.4E-5 T 14-10-2018 C2I25_16690 dc17299247f544c03e3cb03ff99cac40 381 Pfam PF01391 Collagen triple helix repeat (20 copies) 187 245 1.5E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_16690 dc17299247f544c03e3cb03ff99cac40 381 Pfam PF01391 Collagen triple helix repeat (20 copies) 142 193 1.6E-6 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_16690 dc17299247f544c03e3cb03ff99cac40 381 Pfam PF01391 Collagen triple helix repeat (20 copies) 91 145 1.8E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_16690 dc17299247f544c03e3cb03ff99cac40 381 Pfam PF01391 Collagen triple helix repeat (20 copies) 40 97 1.4E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_09790 5301317a2a3c37cb3ce088ae3fff52c3 63 Pfam PF13080 Protein of unknown function (DUF3926) 18 60 3.5E-24 T 14-10-2018 IPR025076 Protein of unknown function DUF3926 C2I25_25895 b1b83df95b9dc30cfcf6757960d1f1ce 305 Pfam PF00892 EamA-like transporter family 4 134 2.1E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_25895 b1b83df95b9dc30cfcf6757960d1f1ce 305 Pfam PF00892 EamA-like transporter family 149 287 7.7E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_25895 b1b83df95b9dc30cfcf6757960d1f1ce 305 SUPERFAMILY SSF103481 186 290 2.75E-16 T 14-10-2018 C2I25_25895 b1b83df95b9dc30cfcf6757960d1f1ce 305 SUPERFAMILY SSF103481 37 139 2.09E-14 T 14-10-2018 C2I25_15025 a736eaa96313844239ca5cb847463972 90 Gene3D G3DSA:1.10.10.10 1 89 4.2E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15025 a736eaa96313844239ca5cb847463972 90 SUPERFAMILY SSF46785 3 82 9.69E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_15025 a736eaa96313844239ca5cb847463972 90 SMART SM00418 3 81 3.7E-30 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_15025 a736eaa96313844239ca5cb847463972 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 4.5E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_15025 a736eaa96313844239ca5cb847463972 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 4.5E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_15025 a736eaa96313844239ca5cb847463972 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 4.5E-15 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_15025 a736eaa96313844239ca5cb847463972 90 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 3.7E-18 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_04875 3f6af98953374eccd58066f7755033a8 266 SUPERFAMILY SSF103473 13 248 1.44E-7 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_04875 3f6af98953374eccd58066f7755033a8 266 Gene3D G3DSA:1.20.1250.20 6 251 1.7E-7 T 14-10-2018 C2I25_04875 3f6af98953374eccd58066f7755033a8 266 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 14 251 1.2E-92 T 14-10-2018 IPR022493 Integral membrane YkoY C2I25_04875 3f6af98953374eccd58066f7755033a8 266 Pfam PF03741 Integral membrane protein TerC family 18 210 4.8E-52 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I25_13735 e73676fd0c332133f9a90380dd6b615f 114 Gene3D G3DSA:1.10.10.10 1 114 1.3E-41 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_13735 e73676fd0c332133f9a90380dd6b615f 114 SUPERFAMILY SSF46785 2 105 1.63E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_13735 e73676fd0c332133f9a90380dd6b615f 114 Pfam PF01638 HxlR-like helix-turn-helix 14 102 1.5E-39 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_12710 d7dafe7f1587881c2d36c5780a9bae11 174 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 162 1.2E-34 T 14-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_12710 d7dafe7f1587881c2d36c5780a9bae11 174 Gene3D G3DSA:1.20.120.1200 5 166 8.2E-38 T 14-10-2018 C2I25_24715 e816a85afb3204b78015b6f2f3d24529 348 PIRSF PIRSF012608 1 348 1.6E-143 T 14-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 C2I25_24715 e816a85afb3204b78015b6f2f3d24529 348 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 9 340 1.3E-112 T 14-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 C2I25_22805 3016e93ee79252d2b80176447794c6d4 123 Pfam PF06993 Protein of unknown function (DUF1304) 11 120 2.4E-39 T 14-10-2018 IPR009732 Protein of unknown function DUF1304 C2I25_07445 90f1cccf3ac81212daf7b428774c69b1 76 SUPERFAMILY SSF64307 5 75 4.58E-25 T 14-10-2018 IPR036868 TusA-like domain superfamily C2I25_07445 90f1cccf3ac81212daf7b428774c69b1 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 14-10-2018 IPR001455 TusA-like domain C2I25_07445 90f1cccf3ac81212daf7b428774c69b1 76 Pfam PF01206 Sulfurtransferase TusA 7 75 3.9E-24 T 14-10-2018 IPR001455 TusA-like domain C2I25_07445 90f1cccf3ac81212daf7b428774c69b1 76 Gene3D G3DSA:3.30.110.40 1 76 7.6E-29 T 14-10-2018 IPR036868 TusA-like domain superfamily C2I25_19045 78461ffe948e692da3b56cf570b88565 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 1.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_19045 78461ffe948e692da3b56cf570b88565 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 1.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_19045 78461ffe948e692da3b56cf570b88565 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 129 149 1.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_19045 78461ffe948e692da3b56cf570b88565 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 1.0E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_19045 78461ffe948e692da3b56cf570b88565 150 SUPERFAMILY SSF46785 19 149 7.68E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_19045 78461ffe948e692da3b56cf570b88565 150 SMART SM00347 43 139 5.3E-23 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_19045 78461ffe948e692da3b56cf570b88565 150 Pfam PF01047 MarR family 48 104 2.6E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_19045 78461ffe948e692da3b56cf570b88565 150 Gene3D G3DSA:1.10.10.10 13 150 4.5E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17030 9ff0f5e802ddb9a7cddf56f3924617e2 228 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 211 21.34 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 C2I25_17030 9ff0f5e802ddb9a7cddf56f3924617e2 228 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 9 210 7.1E-35 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 C2I25_17030 9ff0f5e802ddb9a7cddf56f3924617e2 228 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 108 207 8.7E-31 T 14-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 C2I25_17030 9ff0f5e802ddb9a7cddf56f3924617e2 228 Gene3D G3DSA:2.160.20.70 101 226 3.8E-37 T 14-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 C2I25_17030 9ff0f5e802ddb9a7cddf56f3924617e2 228 SUPERFAMILY SSF63848 106 207 3.27E-30 T 14-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 C2I25_17030 9ff0f5e802ddb9a7cddf56f3924617e2 228 Gene3D G3DSA:3.30.160.540 7 87 1.8E-28 T 14-10-2018 C2I25_22215 3b31a8ccb01f01091e44284b900dc6e5 314 Gene3D G3DSA:3.20.20.190 23 314 1.3E-127 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_22215 3b31a8ccb01f01091e44284b900dc6e5 314 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 43 305 8.5E-51 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I25_22215 3b31a8ccb01f01091e44284b900dc6e5 314 SUPERFAMILY SSF51695 36 311 1.39E-73 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_24355 b2eb937c46da65e54eb8c679d29d0f66 303 SUPERFAMILY SSF103481 191 292 4.58E-15 T 14-10-2018 C2I25_24355 b2eb937c46da65e54eb8c679d29d0f66 303 SUPERFAMILY SSF103481 39 142 1.31E-17 T 14-10-2018 C2I25_24355 b2eb937c46da65e54eb8c679d29d0f66 303 Pfam PF00892 EamA-like transporter family 153 287 1.4E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_24355 b2eb937c46da65e54eb8c679d29d0f66 303 Pfam PF00892 EamA-like transporter family 7 138 3.9E-29 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_13680 d77386aaf4c1cf6bcd3365bd65cae12c 84 Pfam PF13127 Protein of unknown function (DUF3955) 18 76 1.2E-17 T 14-10-2018 IPR025016 Protein of unknown function DUF3955 C2I25_24335 3647dfc299ea02cc9b126f9251595970 274 Pfam PF10978 Protein of unknown function (DUF2785) 81 249 2.8E-51 T 14-10-2018 IPR021247 Protein of unknown function DUF2785 C2I25_02360 ea6b0e8069ed61a4115f1e80f526bad2 214 PIRSF PIRSF036613 1 214 2.0E-142 T 14-10-2018 IPR012072 LytTR signal transduction protein, putative C2I25_02360 ea6b0e8069ed61a4115f1e80f526bad2 214 Gene3D G3DSA:2.40.50.40 106 176 4.2E-32 T 14-10-2018 C2I25_02360 ea6b0e8069ed61a4115f1e80f526bad2 214 Gene3D G3DSA:2.20.25.10 177 214 3.4E-24 T 14-10-2018 C2I25_02360 ea6b0e8069ed61a4115f1e80f526bad2 214 SMART SM00850 116 213 5.8E-30 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_02360 ea6b0e8069ed61a4115f1e80f526bad2 214 Pfam PF04397 LytTr DNA-binding domain 117 212 9.7E-28 T 14-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I25_21905 28823b10836bfae738dde6b6a83a4252 133 Gene3D G3DSA:1.20.5.340 78 125 4.0E-5 T 14-10-2018 C2I25_13670 6b2b1322ca9dbbe155bf258d53430849 134 Hamap MF_01048 Protein PsiE [psiE]. 1 134 26.344 T 14-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 C2I25_13670 6b2b1322ca9dbbe155bf258d53430849 134 PIRSF PIRSF029598 1 134 6.1E-51 T 14-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 C2I25_13670 6b2b1322ca9dbbe155bf258d53430849 134 Pfam PF06146 Phosphate-starvation-inducible E 57 121 7.8E-17 T 14-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like C2I25_08585 efaecbe9578a3001abd3f3bdf1bc0300 174 Gene3D G3DSA:2.60.40.3830 36 174 8.9E-54 T 14-10-2018 C2I25_08585 efaecbe9578a3001abd3f3bdf1bc0300 174 Pfam PF16167 Domain of unknown function (DUF4871) 44 171 5.2E-84 T 14-10-2018 IPR032366 Protein of unknown function DUF4871 C2I25_06785 a64e222e041588eb71f82d0c0afc224a 618 Pfam PF03235 Protein of unknown function DUF262 10 274 7.5E-36 T 14-10-2018 IPR004919 Domain of unknown function DUF262 C2I25_21380 e701a84d934de626077d92721d6bca4c 276 Pfam PF12730 ABC-2 family transporter protein 7 198 1.1E-10 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I25_05015 b08328ce8429abdc32aede1d713c8357 197 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 1.3E-12 T 14-10-2018 IPR023833 Signal peptide, camelysin C2I25_05015 b08328ce8429abdc32aede1d713c8357 197 Pfam PF12389 Camelysin metallo-endopeptidase 2 196 1.2E-92 T 14-10-2018 IPR022121 Peptidase M73, camelysin C2I25_23765 10fd493abf1dabc33787eea1564f029d 244 Pfam PF12811 Bax inhibitor 1 like 5 240 2.7E-66 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 C2I25_23765 10fd493abf1dabc33787eea1564f029d 244 PIRSF PIRSF009160 1 243 1.7E-79 T 14-10-2018 IPR010539 Protein of unknown function UCP009160 C2I25_27465 7341016ac7a1a5f34f61d45703a91db2 83 Pfam PF00196 Bacterial regulatory proteins, luxR family 4 55 3.6E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_27465 7341016ac7a1a5f34f61d45703a91db2 83 Gene3D G3DSA:1.10.10.10 2 66 1.9E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_27465 7341016ac7a1a5f34f61d45703a91db2 83 SUPERFAMILY SSF46894 4 66 1.9E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I25_27465 7341016ac7a1a5f34f61d45703a91db2 83 SMART SM00421 2 59 1.9E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I25_17145 5e4be4a4d667699cab33523576afdcab 214 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 15 205 4.2E-39 T 14-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like C2I25_17350 2387f7d558c0b8de7c6e787c5bd5e825 92 Hamap MF_01448 UPF0473 protein . 2 88 18.94 T 14-10-2018 IPR009711 Uncharacterised protein family UPF0473 C2I25_17350 2387f7d558c0b8de7c6e787c5bd5e825 92 Pfam PF06949 Protein of unknown function (DUF1292) 11 86 2.0E-15 T 14-10-2018 IPR009711 Uncharacterised protein family UPF0473 C2I25_08230 70a21a233f1b1761e9c3667af9a26d4c 140 SUPERFAMILY SSF52402 1 140 2.76E-30 T 14-10-2018 C2I25_08230 70a21a233f1b1761e9c3667af9a26d4c 140 PRINTS PR01438 Universal stress protein signature 2 20 2.8E-19 T 14-10-2018 IPR006015 Universal stress protein A C2I25_08230 70a21a233f1b1761e9c3667af9a26d4c 140 PRINTS PR01438 Universal stress protein signature 100 112 2.8E-19 T 14-10-2018 IPR006015 Universal stress protein A C2I25_08230 70a21a233f1b1761e9c3667af9a26d4c 140 PRINTS PR01438 Universal stress protein signature 118 140 2.8E-19 T 14-10-2018 IPR006015 Universal stress protein A C2I25_08230 70a21a233f1b1761e9c3667af9a26d4c 140 Gene3D G3DSA:3.40.50.620 1 140 3.9E-34 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I25_08230 70a21a233f1b1761e9c3667af9a26d4c 140 Pfam PF00582 Universal stress protein family 1 140 1.4E-28 T 14-10-2018 IPR006016 UspA C2I25_23680 196b652ca374116d3aa3a92eb2a8d635 192 Pfam PF13796 Putative sensor 11 186 3.2E-24 T 14-10-2018 IPR025828 Putative sensor domain C2I25_03265 89912d5ac8f745feca95535c604084ad 149 SMART SM00418 13 91 0.0043 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I25_03265 89912d5ac8f745feca95535c604084ad 149 SUPERFAMILY SSF46785 1 91 1.77E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_03265 89912d5ac8f745feca95535c604084ad 149 Gene3D G3DSA:1.10.10.10 3 84 3.7E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_03265 89912d5ac8f745feca95535c604084ad 149 Pfam PF12840 Helix-turn-helix domain 14 67 7.5E-10 T 14-10-2018 C2I25_16155 1ca88d099462c86433e5b651163c21d6 117 Pfam PF11337 Protein of unknown function (DUF3139) 1 86 9.6E-21 T 14-10-2018 IPR021486 Protein of unknown function DUF3139 C2I25_04105 f772e6c727808a211175002c3667d7f4 64 Pfam PF13062 Protein of unknown function (DUF3924) 1 62 4.2E-46 T 14-10-2018 IPR025038 Protein of unknown function DUF3924 C2I25_08335 90f7163629541e977c700577114b1d84 475 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 30 112 1.6E-17 T 14-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I25_08335 90f7163629541e977c700577114b1d84 475 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 7 469 3.5E-200 T 14-10-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00500+2.7.1.201 C2I25_08335 90f7163629541e977c700577114b1d84 475 Pfam PF02378 Phosphotransferase system, EIIC 112 412 2.2E-43 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_08335 90f7163629541e977c700577114b1d84 475 Gene3D G3DSA:3.30.1360.60 2 80 1.2E-25 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_08335 90f7163629541e977c700577114b1d84 475 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_08335 90f7163629541e977c700577114b1d84 475 Pfam PF00367 phosphotransferase system, EIIB 11 43 8.6E-15 T 14-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I25_08335 90f7163629541e977c700577114b1d84 475 SUPERFAMILY SSF55604 8 83 3.66E-19 T 14-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I25_09350 78052a173178679b747ae11377f78294 193 Gene3D G3DSA:1.10.10.60 7 55 4.4E-19 T 14-10-2018 C2I25_09350 78052a173178679b747ae11377f78294 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 56 1.8E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_09350 78052a173178679b747ae11377f78294 193 SUPERFAMILY SSF46689 1 72 2.26E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_09350 78052a173178679b747ae11377f78294 193 SUPERFAMILY SSF48498 78 191 8.01E-39 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_09350 78052a173178679b747ae11377f78294 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_09350 78052a173178679b747ae11377f78294 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_09350 78052a173178679b747ae11377f78294 193 Pfam PF08360 QacR-like protein, C-terminal region 62 192 2.9E-60 T 14-10-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 C2I25_09350 78052a173178679b747ae11377f78294 193 Gene3D G3DSA:1.10.357.10 56 193 1.6E-42 T 14-10-2018 C2I25_02330 0c697978f087f0be076dabcad619ec70 176 Gene3D G3DSA:3.40.630.30 4 170 1.3E-49 T 14-10-2018 C2I25_02330 0c697978f087f0be076dabcad619ec70 176 SUPERFAMILY SSF55729 1 174 8.98E-51 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_02330 0c697978f087f0be076dabcad619ec70 176 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 1.1E-33 T 14-10-2018 IPR000182 GNAT domain C2I25_06060 ffc55719b8d405185d863fcf553a6ae6 165 SUPERFAMILY SSF54909 56 139 1.77E-24 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_06060 ffc55719b8d405185d863fcf553a6ae6 165 Pfam PF03992 Antibiotic biosynthesis monooxygenase 56 129 1.2E-14 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I25_06060 ffc55719b8d405185d863fcf553a6ae6 165 Gene3D G3DSA:3.30.70.3430 1 165 2.7E-51 T 14-10-2018 C2I25_23945 9fa5e7b3b36e114b676b02881190d942 510 Pfam PF00361 Proton-conducting membrane transporter 122 402 1.8E-59 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_23945 9fa5e7b3b36e114b676b02881190d942 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 71 96 2.5E-14 T 14-10-2018 C2I25_23945 9fa5e7b3b36e114b676b02881190d942 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 99 119 2.5E-14 T 14-10-2018 C2I25_23945 9fa5e7b3b36e114b676b02881190d942 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 2.5E-14 T 14-10-2018 C2I25_23945 9fa5e7b3b36e114b676b02881190d942 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 2.5E-14 T 14-10-2018 C2I25_23945 9fa5e7b3b36e114b676b02881190d942 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 301 313 2.5E-14 T 14-10-2018 C2I25_23945 9fa5e7b3b36e114b676b02881190d942 510 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 109 1.2E-7 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I25_26380 253ed62ba723a13348acfd68252cd03d 70 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 20 58 1.6E-6 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I25_26380 253ed62ba723a13348acfd68252cd03d 70 Gene3D G3DSA:1.10.150.130 14 67 9.2E-8 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I25_26115 75fd318328c83772500dd9e48df21cd2 131 Gene3D G3DSA:3.30.1330.40 3 131 6.0E-36 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 C2I25_26115 75fd318328c83772500dd9e48df21cd2 131 SUPERFAMILY SSF55298 6 130 8.17E-35 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 C2I25_26115 75fd318328c83772500dd9e48df21cd2 131 Pfam PF01042 Endoribonuclease L-PSP 12 129 4.0E-32 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 C2I25_14115 99007e02d074a7ff8de4e2ebcdf29137 282 Gene3D G3DSA:1.10.287.850 1 94 1.8E-23 T 14-10-2018 C2I25_14115 99007e02d074a7ff8de4e2ebcdf29137 282 Pfam PF06013 Proteins of 100 residues with WXG 3 88 2.3E-12 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_14115 99007e02d074a7ff8de4e2ebcdf29137 282 SUPERFAMILY SSF140453 3 98 1.31E-16 T 14-10-2018 IPR036689 ESAT-6-like superfamily C2I25_14115 99007e02d074a7ff8de4e2ebcdf29137 282 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 1.0E-18 T 14-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I25_05520 47cffac907ccebad5cd1f9914d2ab9b3 262 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 63 254 1.6E-49 T 14-10-2018 IPR018728 Domain of unknown function DUF2268 C2I25_02470 ee0697044c15101603fd7bbbb769c043 87 SUPERFAMILY SSF46689 1 85 1.16E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_07675 7a216716b727448c502f74bfced54278 34 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 7 30 6.1E-5 T 14-10-2018 IPR023833 Signal peptide, camelysin C2I25_19985 5a550890d86f5f289b2f13e9bf6367f3 93 Pfam PF05239 PRC-barrel domain 2 78 1.2E-13 T 14-10-2018 IPR027275 PRC-barrel domain C2I25_19985 5a550890d86f5f289b2f13e9bf6367f3 93 SUPERFAMILY SSF50346 1 75 7.59E-15 T 14-10-2018 IPR011033 PRC-barrel-like superfamily C2I25_19985 5a550890d86f5f289b2f13e9bf6367f3 93 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 4 76 8.4E-26 T 14-10-2018 IPR014238 Sporulation protein YlmC/YmxH C2I25_19985 5a550890d86f5f289b2f13e9bf6367f3 93 Gene3D G3DSA:2.30.30.240 2 78 8.0E-13 T 14-10-2018 C2I25_13960 a0eadd008e61771ea7abc44cdf977e92 128 Pfam PF13074 Protein of unknown function (DUF3938) 25 126 5.0E-70 T 14-10-2018 IPR025070 Protein of unknown function DUF3938 C2I25_12400 ede1921e17244f7378161c838bc2dbf5 376 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 285 330 1.4E-6 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I25_12400 ede1921e17244f7378161c838bc2dbf5 376 SUPERFAMILY SSF55874 245 364 2.23E-11 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_12400 ede1921e17244f7378161c838bc2dbf5 376 Pfam PF07730 Histidine kinase 178 241 9.9E-20 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I25_12400 ede1921e17244f7378161c838bc2dbf5 376 Gene3D G3DSA:3.30.565.10 242 365 3.1E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I25_21335 c8e7bbd337a897fe451fd8bfc99d2bc9 322 SUPERFAMILY SSF48576 66 298 1.44E-23 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I25_21335 c8e7bbd337a897fe451fd8bfc99d2bc9 322 Pfam PF00348 Polyprenyl synthetase 113 268 2.1E-6 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 C2I25_21335 c8e7bbd337a897fe451fd8bfc99d2bc9 322 Gene3D G3DSA:1.10.600.10 9 308 4.8E-23 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I25_05670 fd576e2e54b2c7141f67eb4b7e69f0b0 59 Pfam PF09388 Spo0E like sporulation regulatory protein 3 39 7.2E-15 T 14-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I25_05670 fd576e2e54b2c7141f67eb4b7e69f0b0 59 SUPERFAMILY SSF140500 3 49 4.19E-15 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_05670 fd576e2e54b2c7141f67eb4b7e69f0b0 59 Gene3D G3DSA:1.20.58.990 1 59 6.1E-19 T 14-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I25_07320 8cd392e652493508187e7bae2a82ed8f 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 237 7.4E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_07320 8cd392e652493508187e7bae2a82ed8f 334 SUPERFAMILY SSF161098 75 236 8.63E-13 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_07320 8cd392e652493508187e7bae2a82ed8f 334 Gene3D G3DSA:1.10.3720.10 69 302 4.6E-14 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_19135 a161a6a1046a24003f84a2c8a39ab84b 189 Pfam PF14097 Stage V sporulation protein AE1 4 183 1.5E-81 T 14-10-2018 IPR025914 Stage V sporulation protein AE C2I25_18315 10f3f14ae8f2f4d042adc5423fb88d74 168 Pfam PF11085 Conserved membrane protein YqhR 16 157 2.2E-40 T 14-10-2018 IPR024563 Uncharacterised protein family YqhR C2I25_18315 10f3f14ae8f2f4d042adc5423fb88d74 168 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 9 148 4.0E-62 T 14-10-2018 IPR024563 Uncharacterised protein family YqhR C2I25_06570 abc37e97ecfe6c21c4d76bf7e99514cb 391 Pfam PF07690 Major Facilitator Superfamily 12 283 2.6E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_06570 abc37e97ecfe6c21c4d76bf7e99514cb 391 Gene3D G3DSA:1.20.1250.20 5 379 2.9E-39 T 14-10-2018 C2I25_06570 abc37e97ecfe6c21c4d76bf7e99514cb 391 SUPERFAMILY SSF103473 4 377 5.36E-47 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_15240 fc55d04a7d32287fddb31f348becc7ff 104 Pfam PF00893 Small Multidrug Resistance protein 1 91 5.3E-26 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I25_15240 fc55d04a7d32287fddb31f348becc7ff 104 Gene3D G3DSA:1.10.3730.20 1 104 5.8E-24 T 14-10-2018 C2I25_15240 fc55d04a7d32287fddb31f348becc7ff 104 SUPERFAMILY SSF103481 4 100 1.2E-13 T 14-10-2018 C2I25_17895 cc0099a2f86f9c331c9ab82deca190f0 121 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 120 2.0E-62 T 14-10-2018 IPR020506 Uncharacterised protein family YqfZ C2I25_04890 836ae9974f7210184208ff357b954d1a 240 Pfam PF01478 Type IV leader peptidase family 103 204 1.1E-13 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 C2I25_04890 836ae9974f7210184208ff357b954d1a 240 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 10 90 5.7E-24 T 14-10-2018 IPR010627 Peptidase A24A, N-terminal C2I25_08000 bd90db0006b0e809f97af782b823a306 79 Pfam PF13214 Protein of unknown function (DUF4022) 1 77 3.7E-51 T 14-10-2018 IPR025095 Protein of unknown function DUF4022 C2I25_05805 b48a277978b7a35b1c02c03a1732e605 284 Pfam PF02517 CAAX protease self-immunity 129 212 5.5E-17 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_14970 f5c210d688ffc76cff660c9debb84089 197 SUPERFAMILY SSF48498 83 193 5.56E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I25_14970 f5c210d688ffc76cff660c9debb84089 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 56 1.5E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I25_14970 f5c210d688ffc76cff660c9debb84089 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I25_14970 f5c210d688ffc76cff660c9debb84089 197 Gene3D G3DSA:1.10.357.10 4 193 8.9E-26 T 14-10-2018 C2I25_14970 f5c210d688ffc76cff660c9debb84089 197 SUPERFAMILY SSF46689 7 74 2.98E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I25_13920 e2902e34c1b0da1c8e747b889e714a0d 147 Pfam PF13123 Protein of unknown function (DUF3978) 1 144 2.0E-96 T 14-10-2018 IPR025010 Protein of unknown function DUF3978 C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 8.2E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 8.2E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 8.2E-20 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 14-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 Pfam PF00717 Peptidase S24-like 35 102 1.2E-20 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 80 92 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 176 2.1E-57 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 SUPERFAMILY SSF51306 26 181 3.92E-52 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I25_20315 a5ae6b0a0c3846fb1932d80b8d52c273 183 Gene3D G3DSA:2.10.109.10 58 182 2.1E-46 T 14-10-2018 C2I25_18580 d056b0e87633e7dbe521c559a5b395ae 299 SUPERFAMILY SSF53659 4 297 5.28E-62 T 14-10-2018 C2I25_18580 d056b0e87633e7dbe521c559a5b395ae 299 PIRSF PIRSF000428 1 299 6.2E-83 T 14-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I25_18580 d056b0e87633e7dbe521c559a5b395ae 299 Pfam PF01515 Phosphate acetyl/butaryl transferase 77 294 6.0E-51 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I25_18580 d056b0e87633e7dbe521c559a5b395ae 299 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 296 2.7E-130 T 14-10-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 C2I25_18580 d056b0e87633e7dbe521c559a5b395ae 299 Gene3D G3DSA:3.40.718.10 3 299 3.3E-107 T 14-10-2018 C2I25_02085 e57e5e47b99c31740f2d11a43e88e32b 343 Pfam PF00144 Beta-lactamase 23 277 1.6E-45 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_02085 e57e5e47b99c31740f2d11a43e88e32b 343 SUPERFAMILY SSF56601 8 326 1.99E-73 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_02085 e57e5e47b99c31740f2d11a43e88e32b 343 Gene3D G3DSA:3.40.710.10 7 337 7.4E-105 T 14-10-2018 C2I25_20010 857012e78a844f62ed8a2667a006cb83 255 Gene3D G3DSA:3.30.1370.160 2 77 1.5E-26 T 14-10-2018 C2I25_20010 857012e78a844f62ed8a2667a006cb83 255 SMART SM00363 179 241 1.5E-11 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_20010 857012e78a844f62ed8a2667a006cb83 255 Gene3D G3DSA:3.10.290.10 178 230 1.1E-10 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I25_20010 857012e78a844f62ed8a2667a006cb83 255 Gene3D G3DSA:3.30.70.330 79 164 2.2E-29 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily C2I25_20010 857012e78a844f62ed8a2667a006cb83 255 SUPERFAMILY SSF55174 34 252 1.7E-38 T 14-10-2018 C2I25_20010 857012e78a844f62ed8a2667a006cb83 255 Pfam PF01479 S4 domain 180 224 6.8E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I25_25005 354a1ae5f95140babceefbca8bce11e1 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 2.8E-25 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_25005 354a1ae5f95140babceefbca8bce11e1 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 1.3E-21 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_17315 bb8943f14524fa603f89e3e23e88e76f 42 Pfam PF13056 Protein of unknown function (DUF3918) 3 42 1.1E-19 T 14-10-2018 IPR025029 Protein of unknown function DUF3918 C2I25_08405 a784013d27d4ec0d4583db7e88aeab17 352 Pfam PF01032 FecCD transport family 33 348 1.4E-93 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_08405 a784013d27d4ec0d4583db7e88aeab17 352 SUPERFAMILY SSF81345 14 348 3.4E-83 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_08405 a784013d27d4ec0d4583db7e88aeab17 352 Gene3D G3DSA:1.10.3470.10 19 352 3.8E-100 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_27815 2e7b2d5023142fd92e58982e2398a9fc 262 Pfam PF13704 Glycosyl transferase family 2 13 99 1.7E-9 T 14-10-2018 C2I25_21825 41372a97f7a2728c7dcf1f68f923faac 310 SUPERFAMILY SSF53590 1 309 7.85E-81 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_21825 41372a97f7a2728c7dcf1f68f923faac 310 Gene3D G3DSA:3.90.245.10 1 309 1.1E-76 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_21825 41372a97f7a2728c7dcf1f68f923faac 310 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 301 4.5E-65 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain C2I25_28070 760cfd4d8b8dac0522064e387a3b3bb1 626 PIRSF PIRSF018968 418 621 1.4E-22 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_28070 760cfd4d8b8dac0522064e387a3b3bb1 626 PIRSF PIRSF018968 1 372 3.4E-40 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_28070 760cfd4d8b8dac0522064e387a3b3bb1 626 Pfam PF02687 FtsX-like permease family 84 179 3.7E-9 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_03610 68a575c008ce206dad3650da2f09e43c 175 Pfam PF14179 YppG-like protein 55 173 4.6E-22 T 14-10-2018 IPR025555 YppG-like protein C2I25_26930 56e95c102a6db9c22163a20977ae1fd0 250 Gene3D G3DSA:3.90.1200.10 81 230 6.8E-11 T 14-10-2018 C2I25_26930 56e95c102a6db9c22163a20977ae1fd0 250 Pfam PF01636 Phosphotransferase enzyme family 21 208 3.0E-14 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_26930 56e95c102a6db9c22163a20977ae1fd0 250 SUPERFAMILY SSF56112 6 224 2.39E-29 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_25770 1ce5cc5be4a3b2b21364e039ffdcd0b6 85 Pfam PF13122 Protein of unknown function (DUF3977) 1 77 6.2E-51 T 14-10-2018 IPR025009 Protein of unknown function DUF3977 C2I25_08595 a0c799c712503f684684d69d8e4b5da3 448 PIRSF PIRSF005348 13 448 3.8E-171 T 14-10-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 C2I25_08595 a0c799c712503f684684d69d8e4b5da3 448 Pfam PF03390 2-hydroxycarboxylate transporter family 32 442 2.1E-161 T 14-10-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 C2I25_01300 52c90255deb575f5d3f63aa1a4d5dae4 491 Gene3D G3DSA:3.90.1300.10 2 490 6.4E-168 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_01300 52c90255deb575f5d3f63aa1a4d5dae4 491 SUPERFAMILY SSF75304 12 488 2.62E-103 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_01300 52c90255deb575f5d3f63aa1a4d5dae4 491 Pfam PF01425 Amidase 31 471 3.2E-78 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I25_18345 4daa8dba4209a9aeac1237736ae5398c 93 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 12 89 2.0E-36 T 14-10-2018 IPR020390 Uncharacterised protein family YqhV C2I25_18345 4daa8dba4209a9aeac1237736ae5398c 93 Pfam PF10942 Protein of unknown function (DUF2619) 19 87 9.0E-28 T 14-10-2018 IPR020390 Uncharacterised protein family YqhV C2I25_15945 97edfeaaf1c937a86c417c34ff09f322 288 Pfam PF00561 alpha/beta hydrolase fold 48 263 1.5E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I25_15945 97edfeaaf1c937a86c417c34ff09f322 288 SUPERFAMILY SSF53474 9 274 3.56E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_21130 cf0d7ee503dec8bffb7f565446429538 225 Pfam PF04172 LrgB-like family 10 222 8.4E-70 T 14-10-2018 IPR007300 CidB/LrgB family C2I25_24985 a1f78ef28955a0972a45c8f2a633a95f 273 Pfam PF14279 HNH endonuclease 4 53 2.4E-13 T 14-10-2018 IPR029471 HNH endonuclease 5 C2I25_05690 3da22a1a2b55ffa9413c73ee04160441 64 PIRSF PIRSF037666 1 59 5.4E-35 T 14-10-2018 IPR017257 Spore germination protein GerPD, predicted C2I25_03840 d45533abcd80d63e156fc75a3963eb37 244 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 21 230 6.6E-75 T 14-10-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 C2I25_22990 5021761d3e6cf85f11af024706d9b472 257 Pfam PF13704 Glycosyl transferase family 2 10 96 4.1E-8 T 14-10-2018 C2I25_10000 6a7237df405b680f6f61bcb20677e6cd 264 Pfam PF03567 Sulfotransferase family 91 259 1.4E-7 T 14-10-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 C2I25_02255 7b94892ec48268bc0cebfd61e00d7333 456 Gene3D G3DSA:3.40.50.1820 105 453 3.3E-86 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_02255 7b94892ec48268bc0cebfd61e00d7333 456 SUPERFAMILY SSF53474 104 436 4.39E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_02255 7b94892ec48268bc0cebfd61e00d7333 456 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 112 260 1.0E-11 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 C2I25_02255 7b94892ec48268bc0cebfd61e00d7333 456 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 299 433 1.7E-8 T 14-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 C2I25_07940 f461484c8a4e307e47020cc9e177f692 374 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 368 7.8E-111 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_07940 f461484c8a4e307e47020cc9e177f692 374 Pfam PF03845 Spore germination protein 13 333 3.6E-57 T 14-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I25_11505 32561e7d15cf01417ccc450297bd0e52 73 Pfam PF10704 Protein of unknown function (DUF2508) 1 69 5.8E-27 T 14-10-2018 IPR019644 Protein of unknown function DUF2508 C2I25_08435 4b22232fa111c92891485660577e4ee7 539 Pfam PF02652 L-lactate permease 16 530 9.1E-177 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I25_08435 4b22232fa111c92891485660577e4ee7 539 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 535 1.0E-183 T 14-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I25_28010 98ae6281db587da8416efd23be6b56ee 233 SMART SM00100 14 133 8.6E-11 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_28010 98ae6281db587da8416efd23be6b56ee 233 Gene3D G3DSA:2.60.120.1460 21 227 2.0E-36 T 14-10-2018 C2I25_28010 98ae6281db587da8416efd23be6b56ee 233 SUPERFAMILY SSF51206 22 139 1.96E-25 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like C2I25_28010 98ae6281db587da8416efd23be6b56ee 233 SUPERFAMILY SSF46785 151 226 1.58E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_28010 98ae6281db587da8416efd23be6b56ee 233 Pfam PF00027 Cyclic nucleotide-binding domain 35 116 1.7E-16 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I25_28010 98ae6281db587da8416efd23be6b56ee 233 Pfam PF13545 Crp-like helix-turn-helix domain 154 224 6.1E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I25_21655 7ab85f8a571f44d971c61dbc9ab32f0c 130 ProDom PD710533 YODI TRANSMEMBRANE MEMBRANE 7 48 1.0E-17 T 14-10-2018 C2I25_27680 aa763ece9516f214dd0070a6255929e8 109 PIRSF PIRSF031804 1 108 1.4E-35 T 14-10-2018 IPR016983 Uncharacterised conserved protein UCP031804 C2I25_27680 aa763ece9516f214dd0070a6255929e8 109 Pfam PF06803 Protein of unknown function (DUF1232) 41 78 2.8E-6 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 C2I25_07260 e2b1fbcce37be53e60cd0a97f4ee5e46 141 Pfam PF13157 Protein of unknown function (DUF3992) 55 134 9.4E-7 T 14-10-2018 IPR025055 Protein of unknown function DUF3992 C2I25_25030 a33e19aaa050d454eb3a76aa109d9c1c 197 Pfam PF16107 Domain of unknown function (DUF4825) 39 131 9.1E-16 T 14-10-2018 IPR032250 Domain of unknown function DUF4825 C2I25_07275 a18656cb0eeb23e5649ee75c454fd1bb 201 Pfam PF09335 SNARE associated Golgi protein 29 154 2.2E-23 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_22050 8409f631f6d0c0f8fb74e0fa4b137fba 224 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 13 179 2.5E-43 T 14-10-2018 IPR014903 Protein of unknown function DUF1796 C2I25_04315 a7bdf1e1b6771c994f081eed7e53bdb3 149 Pfam PF13027 Protein of unknown function (DUF3888) 49 133 1.6E-20 T 14-10-2018 IPR024984 Protein of unknown function DUF3888 C2I25_05725 f07b4c46cc43f14d9e1d995278564f87 197 Pfam PF09335 SNARE associated Golgi protein 43 161 5.1E-25 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_01585 4b077f320361140fd825748bf6f83adf 175 SUPERFAMILY SSF109854 3 167 2.75E-36 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_01585 4b077f320361140fd825748bf6f83adf 175 Gene3D G3DSA:1.20.120.450 3 170 5.6E-39 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_01585 4b077f320361140fd825748bf6f83adf 175 Pfam PF04978 Protein of unknown function (DUF664) 20 166 1.8E-12 T 14-10-2018 IPR007061 Protein of unknown function DUF664 C2I25_15035 40d64ff239f403c827707fd8665b6ced 209 PIRSF PIRSF038959 1 209 1.2E-33 T 14-10-2018 IPR026272 Immunity protein SdpI C2I25_15035 40d64ff239f403c827707fd8665b6ced 209 Pfam PF07853 Protein of unknown function (DUF1648) 11 48 8.6E-12 T 14-10-2018 IPR012867 Domain of unknown function DUF1648 C2I25_15035 40d64ff239f403c827707fd8665b6ced 209 Pfam PF13630 SdpI/YhfL protein family 131 194 2.8E-16 T 14-10-2018 IPR025962 SdpI/YhfL protein family C2I25_01380 91f4a3357c737371d88174c101cbf00f 160 Pfam PF04306 Protein of unknown function (DUF456) 21 156 3.0E-37 T 14-10-2018 IPR007403 Protein of unknown function DUF456 C2I25_02980 2fbbe9eb82ee32075726da40cc26553a 241 Pfam PF03591 AzlC protein 25 165 1.3E-40 T 14-10-2018 IPR011606 Branched-chain amino acid transport, permease C2I25_01960 b045798dff8db85197cd8248356c95d8 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 9.9E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I25_12220 4dd12d3d2be5ce70604762b0e609ab12 140 Pfam PF07486 Cell Wall Hydrolase 24 129 4.3E-18 T 14-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I25_12220 4dd12d3d2be5ce70604762b0e609ab12 140 Gene3D G3DSA:1.10.10.2520 8 92 1.4E-10 T 14-10-2018 C2I25_16520 8ad86e777d5e6ae41785db37dec34950 44 Pfam PF14115 YuzL-like protein 4 43 4.9E-14 T 14-10-2018 IPR025625 YuzL-like protein C2I25_05545 a271d681810a9bfbee3e7147cf9d6b16 244 Gene3D G3DSA:3.40.50.1820 12 238 1.6E-9 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_05545 a271d681810a9bfbee3e7147cf9d6b16 244 SUPERFAMILY SSF53474 16 240 2.65E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_24710 4662b60ec2b840a37f0bce08658b73b6 500 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 490 2.3E-217 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I25_24710 4662b60ec2b840a37f0bce08658b73b6 500 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 1.0E-240 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I25_24710 4662b60ec2b840a37f0bce08658b73b6 500 SUPERFAMILY SSF51905 4 274 3.11E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I25_24710 4662b60ec2b840a37f0bce08658b73b6 500 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 492 54.256 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I25_17285 27c348532a44db408f21cd489c3ffbc7 138 Gene3D G3DSA:1.10.10.10 1 138 8.3E-52 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_17285 27c348532a44db408f21cd489c3ffbc7 138 SUPERFAMILY SSF46785 2 125 9.43E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_17285 27c348532a44db408f21cd489c3ffbc7 138 Pfam PF02082 Transcriptional regulator 1 82 2.2E-26 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type C2I25_17285 27c348532a44db408f21cd489c3ffbc7 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 125 1.1E-34 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type C2I25_17285 27c348532a44db408f21cd489c3ffbc7 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site C2I25_25750 0b8540fac98a5bc0a50e0353bbdfd4d3 198 Pfam PF00583 Acetyltransferase (GNAT) family 63 153 2.5E-13 T 14-10-2018 IPR000182 GNAT domain C2I25_25750 0b8540fac98a5bc0a50e0353bbdfd4d3 198 SUPERFAMILY SSF55729 14 182 2.66E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25750 0b8540fac98a5bc0a50e0353bbdfd4d3 198 Gene3D G3DSA:3.40.630.30 14 179 2.1E-36 T 14-10-2018 C2I25_22960 99dad81e5e32b9a641c62a843fa32e10 294 Pfam PF00892 EamA-like transporter family 6 143 2.3E-26 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_22960 99dad81e5e32b9a641c62a843fa32e10 294 Pfam PF00892 EamA-like transporter family 154 290 1.7E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_22960 99dad81e5e32b9a641c62a843fa32e10 294 SUPERFAMILY SSF103481 40 145 3.53E-15 T 14-10-2018 C2I25_22960 99dad81e5e32b9a641c62a843fa32e10 294 SUPERFAMILY SSF103481 190 291 2.35E-15 T 14-10-2018 C2I25_23395 8bc3c71aa763b64e12614035a030f64d 112 Pfam PF13034 Protein of unknown function (DUF3895) 30 104 2.3E-34 T 14-10-2018 IPR024995 Protein of unknown function DUF3895 C2I25_27120 25fda3dfe2105ff17cbd3a70ad15bcdb 303 Pfam PF00682 HMGL-like 9 280 6.9E-47 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 C2I25_27120 25fda3dfe2105ff17cbd3a70ad15bcdb 303 SUPERFAMILY SSF51569 4 293 4.58E-68 T 14-10-2018 C2I25_27120 25fda3dfe2105ff17cbd3a70ad15bcdb 303 Gene3D G3DSA:3.20.20.70 4 295 1.2E-119 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I25_27825 d41dfcbc0f784b6930adc394c879d8e3 94 Pfam PF13799 Domain of unknown function (DUF4183) 21 91 3.9E-19 T 14-10-2018 IPR025237 Domain of unknown function DUF4183 C2I25_24230 79ef4dd843d9448ca608b6dc235e29fd 253 Pfam PF03746 LamB/YcsF family 4 241 7.3E-104 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I25_24230 79ef4dd843d9448ca608b6dc235e29fd 253 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 247 47.305 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I25_24230 79ef4dd843d9448ca608b6dc235e29fd 253 Gene3D G3DSA:3.20.20.370 2 253 3.8E-105 T 14-10-2018 C2I25_24230 79ef4dd843d9448ca608b6dc235e29fd 253 SUPERFAMILY SSF88713 3 250 4.89E-101 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_22170 d7fdcb67a26cbe635c4f1d2b33831736 115 Pfam PF14079 Domain of unknown function (DUF4260) 3 114 3.5E-43 T 14-10-2018 IPR025356 Protein of unknown function DUF4260 C2I25_28165 81dd6c04cf4db1cf4fb2149937a144dc 399 SUPERFAMILY SSF56322 17 391 7.59E-98 T 14-10-2018 IPR005801 ADC synthase GO:0009058 C2I25_28165 81dd6c04cf4db1cf4fb2149937a144dc 399 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 101 389 1.4E-92 T 14-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 C2I25_28165 81dd6c04cf4db1cf4fb2149937a144dc 399 Gene3D G3DSA:3.60.120.10 1 399 7.9E-159 T 14-10-2018 IPR005801 ADC synthase GO:0009058 C2I25_28165 81dd6c04cf4db1cf4fb2149937a144dc 399 Pfam PF00425 chorismate binding enzyme 122 381 1.9E-81 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal C2I25_15740 975a4585fbf768d5c664e0ef2d7ddee9 181 SUPERFAMILY SSF55144 4 180 7.67E-39 T 14-10-2018 IPR009097 Cyclic phosphodiesterase C2I25_15740 975a4585fbf768d5c664e0ef2d7ddee9 181 Gene3D G3DSA:3.90.1140.10 4 181 2.6E-42 T 14-10-2018 C2I25_15740 975a4585fbf768d5c664e0ef2d7ddee9 181 Pfam PF02834 LigT like Phosphoesterase 99 171 5.0E-9 T 14-10-2018 IPR014051 Phosphoesterase, HXTX C2I25_15740 975a4585fbf768d5c664e0ef2d7ddee9 181 Pfam PF02834 LigT like Phosphoesterase 10 92 8.3E-14 T 14-10-2018 IPR014051 Phosphoesterase, HXTX C2I25_15740 975a4585fbf768d5c664e0ef2d7ddee9 181 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 4 179 1.2E-55 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 C2I25_15740 975a4585fbf768d5c664e0ef2d7ddee9 181 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 3 179 22.219 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 C2I25_09920 16738dbef58f7bce6a2ba6802084729d 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 1.5E-31 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09920 16738dbef58f7bce6a2ba6802084729d 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 21.23 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09920 16738dbef58f7bce6a2ba6802084729d 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 1.0E-34 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09920 16738dbef58f7bce6a2ba6802084729d 84 SUPERFAMILY SSF82697 1 80 1.13E-28 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_09920 16738dbef58f7bce6a2ba6802084729d 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 7.3E-32 T 14-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I25_09920 16738dbef58f7bce6a2ba6802084729d 84 Gene3D G3DSA:3.30.1280.10 1 84 2.9E-36 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I25_21270 af6848f4c7a3e7d5973bea47df946c60 202 SUPERFAMILY SSF53474 2 200 8.51E-59 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_21270 af6848f4c7a3e7d5973bea47df946c60 202 Pfam PF02230 Phospholipase/Carboxylesterase 6 197 9.9E-10 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 C2I25_21270 af6848f4c7a3e7d5973bea47df946c60 202 Gene3D G3DSA:3.40.50.1820 1 202 3.1E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_26195 ad3683a12512dec5417530ccba4accec 307 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 299 2.5E-63 T 14-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain C2I25_26195 ad3683a12512dec5417530ccba4accec 307 SUPERFAMILY SSF53590 2 306 4.32E-79 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_26195 ad3683a12512dec5417530ccba4accec 307 Gene3D G3DSA:3.90.245.10 1 307 1.0E-74 T 14-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I25_08645 1bcb15add0520ab6f2485540268894f0 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 264 1.2E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_08645 1bcb15add0520ab6f2485540268894f0 273 Gene3D G3DSA:1.10.3720.10 3 261 5.2E-56 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_08645 1bcb15add0520ab6f2485540268894f0 273 SUPERFAMILY SSF161098 5 273 1.12E-63 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_25695 a53a9135b80132653903e41e5ea721e6 159 SUPERFAMILY SSF109854 27 152 3.66E-22 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_25695 a53a9135b80132653903e41e5ea721e6 159 Gene3D G3DSA:1.20.120.450 23 153 1.9E-19 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_25695 a53a9135b80132653903e41e5ea721e6 159 Pfam PF12867 DinB superfamily 26 146 4.2E-10 T 14-10-2018 IPR024775 DinB-like domain C2I25_24550 670fc8a8c78daf1e6d7f2f96886cf313 282 SUPERFAMILY SSF52540 1 152 3.06E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_24550 670fc8a8c78daf1e6d7f2f96886cf313 282 Gene3D G3DSA:3.40.50.300 1 186 1.1E-5 T 14-10-2018 C2I25_22530 1d63b6909c3727bbacafc77584ce56a0 253 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_22530 1d63b6909c3727bbacafc77584ce56a0 253 SUPERFAMILY SSF52540 5 223 6.74E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_22530 1d63b6909c3727bbacafc77584ce56a0 253 Gene3D G3DSA:3.40.50.300 1 236 2.8E-66 T 14-10-2018 C2I25_22530 1d63b6909c3727bbacafc77584ce56a0 253 SMART SM00382 30 219 3.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_22530 1d63b6909c3727bbacafc77584ce56a0 253 Pfam PF00005 ABC transporter 21 162 1.3E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_02525 66cb30b2f41e87d74c9cf418673e1845 179 SUPERFAMILY SSF46785 5 170 1.01E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_02525 66cb30b2f41e87d74c9cf418673e1845 179 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 2.5E-14 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_02525 66cb30b2f41e87d74c9cf418673e1845 179 Gene3D G3DSA:1.10.10.10 2 89 2.4E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_21465 c7f5eec9dd970fa62b5a0a0c26c7298e 44 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 44 14.919 T 14-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 C2I25_21465 c7f5eec9dd970fa62b5a0a0c26c7298e 44 Pfam PF08179 Small acid-soluble spore protein P family 8 39 1.9E-14 T 14-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 C2I25_17980 dc29b4476d7336b172bb355e35253a6f 57 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 1 54 7.0E-13 T 14-10-2018 IPR024490 Protein of unknown function DUF2759 C2I25_17980 dc29b4476d7336b172bb355e35253a6f 57 Pfam PF10958 Protein of unknown function (DUF2759) 6 55 3.0E-24 T 14-10-2018 IPR024490 Protein of unknown function DUF2759 C2I25_16765 cd11da4a678738483cdd2b15e8c34cb1 264 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 187 204 - T 14-10-2018 IPR000540 Flagellar motor protein MotA, conserved site C2I25_16765 cd11da4a678738483cdd2b15e8c34cb1 264 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 219 5.5E-25 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel C2I25_16060 84ff100133507238178fad40837a8bcc 65 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 39 53 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_16060 84ff100133507238178fad40837a8bcc 65 Gene3D G3DSA:1.10.8.910 6 65 2.2E-31 T 14-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I25_16060 84ff100133507238178fad40837a8bcc 65 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 6 60 4.9E-23 T 14-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I25_16060 84ff100133507238178fad40837a8bcc 65 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 21 30 - T 14-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I25_12875 337266ebb104c732044ddad230cb3947 330 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 327 4.2E-131 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 C2I25_12875 337266ebb104c732044ddad230cb3947 330 Gene3D G3DSA:3.40.50.720 4 256 2.7E-135 T 14-10-2018 C2I25_12875 337266ebb104c732044ddad230cb3947 330 Gene3D G3DSA:3.90.25.10 174 320 2.7E-135 T 14-10-2018 C2I25_12875 337266ebb104c732044ddad230cb3947 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 253 1.3E-56 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I25_12875 337266ebb104c732044ddad230cb3947 330 SUPERFAMILY SSF51735 1 328 1.29E-96 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_00850 fcf39155b20e6dae2d1005ddec9db4eb 325 SUPERFAMILY SSF158499 194 255 4.71E-17 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_00850 fcf39155b20e6dae2d1005ddec9db4eb 325 Gene3D G3DSA:1.10.10.630 191 261 1.6E-21 T 14-10-2018 IPR034829 DnaD-like domain superfamily C2I25_00850 fcf39155b20e6dae2d1005ddec9db4eb 325 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 193 261 2.7E-20 T 14-10-2018 IPR006343 DnaD domain C2I25_00850 fcf39155b20e6dae2d1005ddec9db4eb 325 Pfam PF07261 Replication initiation and membrane attachment 194 262 1.2E-16 T 14-10-2018 IPR006343 DnaD domain C2I25_23050 ed5881d25890fd7406a3853de31bfce8 837 Pfam PF01391 Collagen triple helix repeat (20 copies) 591 647 4.6E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_23050 ed5881d25890fd7406a3853de31bfce8 837 Pfam PF01391 Collagen triple helix repeat (20 copies) 640 693 4.1E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_12715 32ea691d24513e65e5bbe320b76b12db 104 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 4 104 20.212 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 C2I25_12715 32ea691d24513e65e5bbe320b76b12db 104 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 99 2.3E-24 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like C2I25_07315 2a96ec777f209149273217d9caa51cdf 438 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 415 7.6E-128 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_07315 2a96ec777f209149273217d9caa51cdf 438 Pfam PF05525 Branched-chain amino acid transport protein 8 428 1.7E-141 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_13225 5482e288a82f485c86c069a9ba9681f0 357 Pfam PF00953 Glycosyl transferase family 4 72 231 8.6E-39 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 C2I25_13225 5482e288a82f485c86c069a9ba9681f0 357 ProSitePatterns PS01348 MraY family signature 2. 147 158 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I25_08720 d84914e827f6c29b5832171a9bb17f32 516 ProSitePatterns PS01303 BCCT family of transporters signature. 316 325 - T 14-10-2018 IPR018093 BCCT transporter, conserved site C2I25_08720 d84914e827f6c29b5832171a9bb17f32 516 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 499 3.6E-185 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I25_08720 d84914e827f6c29b5832171a9bb17f32 516 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 499 1.9E-148 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I25_21840 68fce4dddad081ce71927cb1e5f7122b 279 SUPERFAMILY SSF55729 143 271 5.87E-14 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_21840 68fce4dddad081ce71927cb1e5f7122b 279 Pfam PF08445 FR47-like protein 211 272 1.5E-8 T 14-10-2018 IPR013653 FR47-like GO:0016747 C2I25_21840 68fce4dddad081ce71927cb1e5f7122b 279 Gene3D G3DSA:3.40.630.30 140 278 2.1E-12 T 14-10-2018 C2I25_03080 70a092197f608a45677a4b81780d4230 319 Gene3D G3DSA:1.20.120.1030 9 131 1.4E-52 T 14-10-2018 IPR038245 MogR, N-terminal domain superfamily C2I25_03080 70a092197f608a45677a4b81780d4230 319 Pfam PF12181 DNA binding domain of the motility gene repressor (MogR) 16 163 5.7E-76 T 14-10-2018 IPR021009 Motility repressor MogR, DNA-dinding domain C2I25_26450 6c6cf00b81959749897a981fdd5015c4 165 SUPERFAMILY SSF46785 4 164 2.86E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_26450 6c6cf00b81959749897a981fdd5015c4 165 Gene3D G3DSA:1.10.10.10 1 100 3.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_26450 6c6cf00b81959749897a981fdd5015c4 165 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 1.3E-17 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_12270 57773ce97b8ed5af75a5916c645268c2 312 Pfam PF01497 Periplasmic binding protein 95 286 4.1E-33 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_12270 57773ce97b8ed5af75a5916c645268c2 312 SUPERFAMILY SSF53807 36 288 3.18E-56 T 14-10-2018 C2I25_12270 57773ce97b8ed5af75a5916c645268c2 312 Gene3D G3DSA:3.40.50.1980 162 312 3.7E-33 T 14-10-2018 C2I25_12270 57773ce97b8ed5af75a5916c645268c2 312 Gene3D G3DSA:3.40.50.1980 25 160 1.1E-31 T 14-10-2018 C2I25_22325 c433cf7a287115c37a8e71e31f72d3e2 170 Pfam PF10901 Protein of unknown function (DUF2690) 36 147 8.5E-30 T 14-10-2018 IPR021224 Protein of unknown function DUF2690 C2I25_07945 2476884c809896178a2076422b6c30f7 492 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 17 477 1.8E-168 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_07945 2476884c809896178a2076422b6c30f7 492 PIRSF PIRSF005690 6 492 3.0E-163 T 14-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I25_24640 abb5d270d3bb90e31f37d4a9af780959 397 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 395 3.9E-48 T 14-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I25_24640 abb5d270d3bb90e31f37d4a9af780959 397 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 79 2.0E-19 T 14-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I25_15540 b1935d6144f424cd983a793992ca566c 165 Gene3D G3DSA:3.30.70.1450 85 162 4.6E-17 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_15540 b1935d6144f424cd983a793992ca566c 165 Pfam PF02080 TrkA-C domain 89 158 1.2E-13 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I25_15540 b1935d6144f424cd983a793992ca566c 165 PIRSF PIRSF005028 1 161 8.4E-52 T 14-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT C2I25_15540 b1935d6144f424cd983a793992ca566c 165 SUPERFAMILY SSF116726 69 156 1.57E-16 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I25_03440 63ae3f3f2fd0b6e19e356757c2ba1421 404 Pfam PF04932 O-Antigen ligase 193 331 5.1E-19 T 14-10-2018 IPR007016 O-antigen ligase-related C2I25_05025 0924c6f256ea24a4094f89765e509643 195 Pfam PF12389 Camelysin metallo-endopeptidase 2 194 3.6E-88 T 14-10-2018 IPR022121 Peptidase M73, camelysin C2I25_05025 0924c6f256ea24a4094f89765e509643 195 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 13 44 4.6E-11 T 14-10-2018 IPR023833 Signal peptide, camelysin C2I25_25575 8ebc34edb17f8da76e89ea9ef6a5d064 121 Gene3D G3DSA:3.90.1150.30 3 121 2.4E-40 T 14-10-2018 IPR038056 YjbR-like superfamily C2I25_25575 8ebc34edb17f8da76e89ea9ef6a5d064 121 SUPERFAMILY SSF142906 5 119 4.58E-38 T 14-10-2018 IPR038056 YjbR-like superfamily C2I25_25575 8ebc34edb17f8da76e89ea9ef6a5d064 121 Pfam PF04237 YjbR 13 106 8.8E-24 T 14-10-2018 IPR007351 Uncharacterised protein YjbR C2I25_25680 5da3a34fda913e80ed9843b740735f39 127 Pfam PF13789 Domain of unknown function (DUF4181) 18 119 1.3E-30 T 14-10-2018 IPR025441 Protein of unknown function DUF4181 C2I25_23885 dbeb9c0c652e9acf5be9d3ad0327e4b5 388 Pfam PF00144 Beta-lactamase 62 371 4.7E-64 T 14-10-2018 IPR001466 Beta-lactamase-related C2I25_23885 dbeb9c0c652e9acf5be9d3ad0327e4b5 388 SUPERFAMILY SSF56601 63 370 2.58E-76 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I25_23885 dbeb9c0c652e9acf5be9d3ad0327e4b5 388 Gene3D G3DSA:3.40.710.10 47 388 5.4E-132 T 14-10-2018 C2I25_25565 102577748ebe4ab31eff2b24b00c63f7 138 SUPERFAMILY SSF55729 13 138 1.66E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_25565 102577748ebe4ab31eff2b24b00c63f7 138 Pfam PF00583 Acetyltransferase (GNAT) family 36 116 1.3E-12 T 14-10-2018 IPR000182 GNAT domain C2I25_25565 102577748ebe4ab31eff2b24b00c63f7 138 Gene3D G3DSA:3.40.630.30 35 138 4.5E-29 T 14-10-2018 C2I25_19460 7dbe4be7b480d380720580305cac647c 144 Pfam PF14040 Deoxyribonuclease NucA/NucB 46 130 9.1E-11 T 14-10-2018 IPR029476 Deoxyribonuclease NucA/NucB C2I25_26900 fc7a0998a8a16bc6bd3a9da0f9e18a1e 118 SUPERFAMILY SSF49464 39 100 1.04E-6 T 14-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily C2I25_12095 0f53644326a8f12b7dc202b496e7e3b3 67 Pfam PF04328 Selenoprotein, putative 4 67 6.2E-23 T 14-10-2018 IPR007423 Selenoprotein, putative C2I25_19150 39e2c202765e8f1e997010d96532136b 288 Pfam PF06207 Protein of unknown function (DUF1002) 34 251 5.3E-79 T 14-10-2018 IPR009343 Protein of unknown function DUF1002 C2I25_28015 dfbac23066a5a8992b3a4fff66b29329 141 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 137 1.9E-28 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ C2I25_27740 9ebd776d881c5bd14656a80fe8b2b29a 277 Pfam PF13120 Domain of unknown function (DUF3974) 1 126 2.2E-86 T 14-10-2018 IPR025005 Domain of unknown function DUF3974 C2I25_23045 35b807a814515c89218a0626170457f3 823 Pfam PF01391 Collagen triple helix repeat (20 copies) 625 682 1.7E-7 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_23045 35b807a814515c89218a0626170457f3 823 Pfam PF01391 Collagen triple helix repeat (20 copies) 580 631 1.6E-6 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_10605 57046258dae911a1e249287cf1e4759e 177 SUPERFAMILY SSF103473 8 172 1.16E-24 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_10605 57046258dae911a1e249287cf1e4759e 177 Gene3D G3DSA:1.20.1250.20 2 176 3.1E-25 T 14-10-2018 C2I25_10605 57046258dae911a1e249287cf1e4759e 177 Pfam PF07690 Major Facilitator Superfamily 9 171 6.3E-19 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_04490 7b2e7c1a145d93d16f8f2a54fcf9a8a3 184 Pfam PF14595 Thioredoxin 10 138 1.0E-39 T 14-10-2018 C2I25_04490 7b2e7c1a145d93d16f8f2a54fcf9a8a3 184 SUPERFAMILY SSF52833 47 137 1.43E-8 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_04490 7b2e7c1a145d93d16f8f2a54fcf9a8a3 184 Gene3D G3DSA:3.40.30.10 2 168 8.9E-18 T 14-10-2018 C2I25_26235 8310498fc4ff15f85158c1ddce969dcb 267 SUPERFAMILY SSF55729 85 257 8.02E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_26235 8310498fc4ff15f85158c1ddce969dcb 267 Pfam PF13673 Acetyltransferase (GNAT) domain 150 258 4.4E-9 T 14-10-2018 IPR000182 GNAT domain C2I25_26235 8310498fc4ff15f85158c1ddce969dcb 267 Gene3D G3DSA:3.40.630.30 46 259 6.2E-21 T 14-10-2018 C2I25_16310 a279b8a0505a9e4116952a1183848686 129 Pfam PF04186 FxsA cytoplasmic membrane protein 7 114 3.5E-35 T 14-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 C2I25_08290 5d545daf32c910ae1b0e0c6dbe028111 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 8.1E-27 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I25_08290 5d545daf32c910ae1b0e0c6dbe028111 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 3.7E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_08290 5d545daf32c910ae1b0e0c6dbe028111 218 Gene3D G3DSA:1.10.3720.10 2 217 2.7E-56 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_08290 5d545daf32c910ae1b0e0c6dbe028111 218 SUPERFAMILY SSF161098 13 199 1.44E-45 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 ProSitePatterns PS01117 MarR-type HTH domain signature. 98 132 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 SMART SM00347 51 159 9.1E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 SUPERFAMILY SSF46785 26 172 8.59E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 8.8E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 135 8.8E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 115 8.8E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 149 169 8.8E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 Gene3D G3DSA:1.10.10.10 14 176 1.1E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_01265 937465c17ed9b0a3b537be0653565f22 181 Pfam PF01047 MarR family 65 123 2.1E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_08915 77b422d8ba8157d3fdb4757abf44bad6 144 Gene3D G3DSA:3.30.1490.190 90 144 8.3E-24 T 14-10-2018 C2I25_08915 77b422d8ba8157d3fdb4757abf44bad6 144 Pfam PF01475 Ferric uptake regulator family 18 135 8.7E-41 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 C2I25_08915 77b422d8ba8157d3fdb4757abf44bad6 144 SUPERFAMILY SSF46785 10 140 1.64E-43 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_08915 77b422d8ba8157d3fdb4757abf44bad6 144 Gene3D G3DSA:1.10.10.10 3 89 1.2E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_18660 94dd927640462631e8bcafa2e6c346ec 322 Pfam PF06081 Aromatic acid exporter family member 1 2 142 1.5E-51 T 14-10-2018 IPR010343 Aromatic acid exporter family member 1 C2I25_18660 94dd927640462631e8bcafa2e6c346ec 322 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 310 7.7E-54 T 14-10-2018 IPR021062 Putative aromatic acid exporter, C-terminal C2I25_18660 94dd927640462631e8bcafa2e6c346ec 322 Gene3D G3DSA:1.20.120.940 140 313 3.0E-53 T 14-10-2018 IPR038323 Putative aromatic acid exporter, C-terminal domain superfamily C2I25_05755 62ae5bd86c6b41e4e2bb9bd30c062ef3 263 Gene3D G3DSA:3.90.1200.10 77 203 4.9E-10 T 14-10-2018 C2I25_05755 62ae5bd86c6b41e4e2bb9bd30c062ef3 263 SUPERFAMILY SSF56112 8 259 1.67E-27 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_05755 62ae5bd86c6b41e4e2bb9bd30c062ef3 263 Pfam PF01636 Phosphotransferase enzyme family 121 181 1.7E-11 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_13500 eb44b8604d7836e9b4d945850287cc78 161 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 36 144 1.3E-6 T 14-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like C2I25_20140 f454d53125566c0918199934725c94d3 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 5.5E-89 T 14-10-2018 IPR005229 Conserved hypothetical protein CHP00255 C2I25_20140 f454d53125566c0918199934725c94d3 291 Pfam PF03755 YicC-like family, N-terminal region 2 156 2.9E-42 T 14-10-2018 IPR013527 YicC-like, N-terminal C2I25_20140 f454d53125566c0918199934725c94d3 291 Pfam PF08340 Domain of unknown function (DUF1732) 207 291 6.4E-38 T 14-10-2018 IPR013551 Domain of unknown function DUF1732 C2I25_12810 b870d9c2f937f89e164489e5036bc265 255 PIRSF PIRSF016557 1 255 1.1E-113 T 14-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 C2I25_12810 b870d9c2f937f89e164489e5036bc265 255 SUPERFAMILY SSF89550 1 204 8.63E-16 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I25_12810 b870d9c2f937f89e164489e5036bc265 255 Gene3D G3DSA:3.20.20.140 1 255 2.6E-99 T 14-10-2018 C2I25_24150 26bf6deb522b1fa2d2d4986ccd8759b9 168 Pfam PF13302 Acetyltransferase (GNAT) domain 47 148 4.8E-17 T 14-10-2018 IPR000182 GNAT domain C2I25_24150 26bf6deb522b1fa2d2d4986ccd8759b9 168 Gene3D G3DSA:3.40.630.30 5 167 5.1E-29 T 14-10-2018 C2I25_24150 26bf6deb522b1fa2d2d4986ccd8759b9 168 SUPERFAMILY SSF55729 7 150 4.75E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_01625 7848ab3a45b84e49410f84ea9c768cb2 626 Pfam PF02687 FtsX-like permease family 84 177 8.5E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_01625 7848ab3a45b84e49410f84ea9c768cb2 626 PIRSF PIRSF018968 1 623 1.1E-137 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_26590 5942cb9de732d4f71d76805d71715a09 373 Pfam PF05065 Phage capsid family 86 287 4.2E-11 T 14-10-2018 IPR024455 Phage capsid C2I25_26590 5942cb9de732d4f71d76805d71715a09 373 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 51 281 7.6E-16 T 14-10-2018 IPR024455 Phage capsid C2I25_26590 5942cb9de732d4f71d76805d71715a09 373 SUPERFAMILY SSF56563 78 358 7.72E-27 T 14-10-2018 C2I25_23310 f31f665830a4210ae4e15526736b3bd6 191 SUPERFAMILY SSF52218 2 191 3.26E-55 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_23310 f31f665830a4210ae4e15526736b3bd6 191 Gene3D G3DSA:3.40.50.360 1 191 2.5E-55 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_23310 f31f665830a4210ae4e15526736b3bd6 191 Pfam PF02525 Flavodoxin-like fold 2 174 3.1E-43 T 14-10-2018 IPR003680 Flavodoxin-like fold C2I25_27855 5af9398c27770a6d1e809945c13fb84b 295 SUPERFAMILY SSF55729 14 277 5.91E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_27855 5af9398c27770a6d1e809945c13fb84b 295 Pfam PF13527 Acetyltransferase (GNAT) domain 16 132 9.5E-19 T 14-10-2018 C2I25_27855 5af9398c27770a6d1e809945c13fb84b 295 Gene3D G3DSA:3.40.630.30 4 158 7.9E-23 T 14-10-2018 C2I25_25620 296ad21f7a8c19cb8297b76536772e4c 106 Gene3D G3DSA:3.10.20.30 5 92 2.0E-19 T 14-10-2018 IPR012675 Beta-grasp domain superfamily C2I25_25620 296ad21f7a8c19cb8297b76536772e4c 106 SUPERFAMILY SSF54292 11 90 3.82E-19 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I25_25620 296ad21f7a8c19cb8297b76536772e4c 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 81 2.2E-12 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 C2I25_18355 dc5db200f430c62462556a688e881497 171 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 171 4.2E-71 T 14-10-2018 IPR014198 Stage III sporulation protein AB C2I25_18355 dc5db200f430c62462556a688e881497 171 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 171 5.3E-56 T 14-10-2018 IPR014198 Stage III sporulation protein AB C2I25_18355 dc5db200f430c62462556a688e881497 171 PIRSF PIRSF021435 1 171 3.7E-74 T 14-10-2018 IPR014198 Stage III sporulation protein AB C2I25_22965 a4e33d3bcb9ea3d55bae0a2edb6be7cc 270 Pfam PF13704 Glycosyl transferase family 2 27 113 2.3E-11 T 14-10-2018 C2I25_05255 d6f9a3645b5e9571392c69ca9d0af30f 243 Pfam PF00756 Putative esterase 15 238 6.0E-49 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 C2I25_05255 d6f9a3645b5e9571392c69ca9d0af30f 243 Gene3D G3DSA:3.40.50.1820 2 241 2.3E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_05255 d6f9a3645b5e9571392c69ca9d0af30f 243 SUPERFAMILY SSF53474 4 239 9.09E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_27175 9a2866e19ab7aafe237c36b7e6c6aee7 33 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 1 24 5.2E-7 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_16425 46ba21f020c08a2123d027d5e2d5b563 293 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 2 267 9.4E-87 T 14-10-2018 IPR014199 Sporulation protein YtxC C2I25_16425 46ba21f020c08a2123d027d5e2d5b563 293 Pfam PF08812 YtxC-like family 55 267 2.8E-56 T 14-10-2018 IPR014199 Sporulation protein YtxC C2I25_16425 46ba21f020c08a2123d027d5e2d5b563 293 PIRSF PIRSF012563 11 285 5.4E-112 T 14-10-2018 IPR014199 Sporulation protein YtxC C2I25_13325 ea6a026929dbe69ad9fabd8c5ada9276 400 Gene3D G3DSA:2.30.42.10 276 378 1.6E-7 T 14-10-2018 C2I25_13325 ea6a026929dbe69ad9fabd8c5ada9276 400 SUPERFAMILY SSF50156 306 390 4.23E-11 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I25_14075 8da49b0010c7b74398d1be3e8fdb19e8 237 Pfam PF02517 CAAX protease self-immunity 143 228 6.1E-19 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_24365 e1a5893df73f279bf2f70ddc997dbcd3 135 Pfam PF13140 Domain of unknown function (DUF3980) 47 133 2.3E-55 T 14-10-2018 IPR025044 Domain of unknown function DUF3980 C2I25_17870 2299d88ceacdd82651e537df99a14dbd 292 Gene3D G3DSA:3.30.70.120 202 277 1.6E-25 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_17870 2299d88ceacdd82651e537df99a14dbd 292 PIRSF PIRSF006483 1 291 5.1E-90 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_17870 2299d88ceacdd82651e537df99a14dbd 292 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 224 1.4E-65 T 14-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I25_17870 2299d88ceacdd82651e537df99a14dbd 292 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 230 284 3.4E-21 T 14-10-2018 IPR019264 Domain of unknown function DUF2179 C2I25_23525 75ae6957dd0515ad96f3c95486ce6e85 156 SUPERFAMILY SSF109854 25 151 2.93E-16 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_23525 75ae6957dd0515ad96f3c95486ce6e85 156 Pfam PF12867 DinB superfamily 26 126 6.9E-10 T 14-10-2018 IPR024775 DinB-like domain C2I25_23525 75ae6957dd0515ad96f3c95486ce6e85 156 Gene3D G3DSA:1.20.120.450 22 150 7.3E-15 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_22730 dba2e83c93220497045051cd580077e2 114 Pfam PF01638 HxlR-like helix-turn-helix 14 102 2.1E-39 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I25_22730 dba2e83c93220497045051cd580077e2 114 Gene3D G3DSA:1.10.10.10 1 114 2.3E-41 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_22730 dba2e83c93220497045051cd580077e2 114 SUPERFAMILY SSF46785 2 106 1.92E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_25225 56032179f78d605b62e56c8ebd360a45 150 Pfam PF07552 Spore Coat Protein X and V domain 29 85 5.8E-20 T 14-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I25_25225 56032179f78d605b62e56c8ebd360a45 150 Pfam PF07552 Spore Coat Protein X and V domain 92 149 1.4E-21 T 14-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I25_03375 bb9897e95430af562a425cd23d81b20c 58 Pfam PF10782 Zinc-finger 2 58 2.6E-28 T 14-10-2018 IPR019718 Protein of unknown function DUF2602 C2I25_23125 b3fa48365538f7203c6c1b4298f319c5 339 Pfam PF13350 Tyrosine phosphatase family 88 338 1.2E-66 T 14-10-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type C2I25_23125 b3fa48365538f7203c6c1b4298f319c5 339 SUPERFAMILY SSF52799 88 337 3.68E-55 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like C2I25_23125 b3fa48365538f7203c6c1b4298f319c5 339 Gene3D G3DSA:3.90.190.10 89 337 2.7E-61 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like C2I25_11965 e70e546b5fbd0ef1a3e06912300b6109 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I25_11965 e70e546b5fbd0ef1a3e06912300b6109 432 SUPERFAMILY SSF103473 13 430 5.23E-87 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_11965 e70e546b5fbd0ef1a3e06912300b6109 432 Pfam PF07690 Major Facilitator Superfamily 27 298 4.9E-42 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I25_13845 cac39623e17e770325715122c73bc05f 198 Pfam PF09335 SNARE associated Golgi protein 31 156 8.6E-25 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_13275 ad4739f737763977aecd442e126cd5f4 234 Gene3D G3DSA:3.40.50.2020 78 234 7.3E-18 T 14-10-2018 C2I25_13275 ad4739f737763977aecd442e126cd5f4 234 Pfam PF00156 Phosphoribosyl transferase domain 142 232 2.7E-9 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I25_13275 ad4739f737763977aecd442e126cd5f4 234 SUPERFAMILY SSF53271 71 232 2.27E-25 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like C2I25_06165 030158d8562273dc0b775f8aba6fc855 403 PIRSF PIRSF037259 1 403 2.5E-138 T 14-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 C2I25_06165 030158d8562273dc0b775f8aba6fc855 403 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 382 8.0E-126 T 14-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 C2I25_28340 4eeced0daf3aa18948073d379fd756d3 332 SUPERFAMILY SSF51445 4 187 1.19E-40 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily C2I25_28340 4eeced0daf3aa18948073d379fd756d3 332 Pfam PF01183 Glycosyl hydrolases family 25 5 168 6.4E-22 T 14-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 C2I25_28340 4eeced0daf3aa18948073d379fd756d3 332 Gene3D G3DSA:3.20.20.80 2 191 1.7E-71 T 14-10-2018 C2I25_15155 922e63ade6f86ab45c7cef23bc4c02cf 56 Pfam PF12669 Virus attachment protein p12 family 4 46 5.6E-11 T 14-10-2018 C2I25_15245 ab9a1aa53bef87bb9a67c24749338b0d 76 Pfam PF13129 Protein of unknown function (DUF3953) 33 72 5.9E-8 T 14-10-2018 IPR025018 Protein of unknown function DUF3953 C2I25_09260 280489a5b525637296ab20237cc2e00f 171 Pfam PF13294 Domain of unknown function (DUF4075) 91 169 8.9E-48 T 14-10-2018 IPR025276 Protein of unknown function DUF4075 C2I25_21435 a321dd73f8c62122471197ce65390df0 193 Gene3D G3DSA:1.10.720.30 7 82 4.2E-5 T 14-10-2018 IPR036361 SAP domain superfamily C2I25_27750 94fb359ef1dd385231f79c3b21da378c 202 SUPERFAMILY SSF53335 35 201 7.0E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_27750 94fb359ef1dd385231f79c3b21da378c 202 Pfam PF01596 O-methyltransferase 37 192 1.1E-25 T 14-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 C2I25_27750 94fb359ef1dd385231f79c3b21da378c 202 Gene3D G3DSA:3.40.50.150 5 202 4.2E-46 T 14-10-2018 C2I25_17210 64608f3852ba7e166e4009974413d8a8 94 Pfam PF13797 Post-transcriptional regulator 8 90 2.3E-31 T 14-10-2018 IPR025716 Post-transcriptional regulator C2I25_00515 1e1a4f1e2198379d5aa4a1e53a924f10 127 Gene3D G3DSA:3.40.30.10 1 79 1.3E-5 T 14-10-2018 C2I25_00515 1e1a4f1e2198379d5aa4a1e53a924f10 127 Pfam PF04134 Protein of unknown function, DUF393 3 109 4.4E-15 T 14-10-2018 IPR007263 Protein of unknown function DUF393 C2I25_00515 1e1a4f1e2198379d5aa4a1e53a924f10 127 SUPERFAMILY SSF52833 2 78 5.56E-8 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_12060 cb4209bec7f3963fccf284003e7dad58 210 Pfam PF03458 UPF0126 domain 6 79 8.6E-20 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 C2I25_12060 cb4209bec7f3963fccf284003e7dad58 210 Pfam PF03458 UPF0126 domain 92 166 1.2E-20 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 C2I25_03795 1c9a0b5db6526e1f7e940e7b49320eee 152 Pfam PF10673 Protein of unknown function (DUF2487) 9 149 6.4E-53 T 14-10-2018 IPR019615 Protein of unknown function DUF2487 C2I25_12300 44cb93f2f857a2228375fd76b547fef8 241 Gene3D G3DSA:3.20.20.190 1 241 2.1E-84 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_12300 44cb93f2f857a2228375fd76b547fef8 241 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 233 2.5E-46 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I25_12300 44cb93f2f857a2228375fd76b547fef8 241 SUPERFAMILY SSF51695 3 240 4.45E-76 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I25_11350 c10f557ebcfd7c6bce65f6b78162d51d 74 ProDom PD057826 YABK 1 74 2.0E-37 T 14-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 C2I25_11350 c10f557ebcfd7c6bce65f6b78162d51d 74 Pfam PF10955 Protein of unknown function (DUF2757) 1 74 1.0E-28 T 14-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 C2I25_21170 b0600d2d9f3dc10bac87c0cad94d999b 302 SUPERFAMILY SSF103481 191 280 1.1E-7 T 14-10-2018 C2I25_21170 b0600d2d9f3dc10bac87c0cad94d999b 302 Pfam PF00892 EamA-like transporter family 148 279 1.2E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_21170 b0600d2d9f3dc10bac87c0cad94d999b 302 Pfam PF00892 EamA-like transporter family 5 135 1.1E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_08105 4a2cb617d9e4c849c3269949cd9297fa 390 Gene3D G3DSA:3.20.20.10 19 262 8.1E-47 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_08105 4a2cb617d9e4c849c3269949cd9297fa 390 Pfam PF01168 Alanine racemase, N-terminal domain 17 262 3.9E-9 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I25_08105 4a2cb617d9e4c849c3269949cd9297fa 390 SUPERFAMILY SSF51419 20 262 1.16E-17 T 14-10-2018 IPR029066 PLP-binding barrel C2I25_19665 4d829e4648a34cf3b200af2b6ab7aa08 42 Pfam PF13790 SR1 protein 1 37 3.1E-19 T 14-10-2018 IPR025236 SR1 protein C2I25_28045 9ae3f91517e87be2978e6558ad2b12e9 245 Pfam PF02535 ZIP Zinc transporter 93 237 2.5E-15 T 14-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I25_04955 c2d7c92d31d074724a49c13f36707192 307 SUPERFAMILY SSF55120 79 299 7.36E-64 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_04955 c2d7c92d31d074724a49c13f36707192 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 301 2.4E-72 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_04955 c2d7c92d31d074724a49c13f36707192 307 Pfam PF00849 RNA pseudouridylate synthase 93 246 1.0E-32 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_04955 c2d7c92d31d074724a49c13f36707192 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 136 150 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I25_04955 c2d7c92d31d074724a49c13f36707192 307 Gene3D G3DSA:3.30.2350.10 85 306 7.8E-63 T 14-10-2018 C2I25_20095 49ab3bd48fd0073fb73c27534f197790 84 ProDom PD060054 MEMBRANE SPANNING TRANSMEMBRANE YBEF 1 81 1.0E-37 T 14-10-2018 IPR020258 Uncharacterised protein family YbeF C2I25_20095 49ab3bd48fd0073fb73c27534f197790 84 Pfam PF10852 Protein of unknown function (DUF2651) 6 78 1.6E-29 T 14-10-2018 IPR020258 Uncharacterised protein family YbeF C2I25_28480 6819ee0944c84dbee4085ca8508c45e3 249 Pfam PF14344 Domain of unknown function (DUF4397) 61 173 7.0E-28 T 14-10-2018 IPR025510 Domain of unknown function DUF4397 C2I25_28480 6819ee0944c84dbee4085ca8508c45e3 249 Pfam PF14344 Domain of unknown function (DUF4397) 172 248 7.8E-8 T 14-10-2018 IPR025510 Domain of unknown function DUF4397 C2I25_14040 353bd60928725b129a02978035873347 48 Pfam PF14115 YuzL-like protein 3 42 1.7E-17 T 14-10-2018 IPR025625 YuzL-like protein C2I25_03635 ab30abbf6bf9bb195071a6379864bc40 332 Pfam PF10720 Protein of unknown function (DUF2515) 18 319 7.4E-127 T 14-10-2018 IPR019658 Protein of unknown function DUF2515 C2I25_06120 283ef043ac5774e1014d719ef6603fd1 158 SUPERFAMILY SSF103473 26 88 5.62E-5 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_06120 283ef043ac5774e1014d719ef6603fd1 158 Pfam PF03703 Bacterial PH domain 72 146 9.0E-15 T 14-10-2018 IPR005182 Domain of unknown function DUF304 C2I25_24235 43bbe75fa699e660f5f86b0841bd7ccc 234 Pfam PF06149 Protein of unknown function (DUF969) 4 219 1.6E-86 T 14-10-2018 IPR010374 Protein of unknown function DUF969 C2I25_13620 f8fba929cd3c5ee4b390e0c7e284c360 354 SUPERFAMILY SSF81345 31 350 6.15E-54 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_13620 f8fba929cd3c5ee4b390e0c7e284c360 354 Pfam PF01032 FecCD transport family 68 350 4.6E-42 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I25_13620 f8fba929cd3c5ee4b390e0c7e284c360 354 Gene3D G3DSA:1.10.3470.10 34 353 6.5E-49 T 14-10-2018 IPR037294 ABC transporter, BtuC-like C2I25_08995 1c1d43701a48533c67f435645f4dfb89 88 Pfam PF14043 WVELL protein 3 75 2.3E-35 T 14-10-2018 IPR026952 WVELL protein C2I25_00605 876dd9c4827c79ef72599cbf0b8e7310 165 Pfam PF05105 Bacteriophage holin family 46 143 4.1E-10 T 14-10-2018 IPR006480 Bacteriophage holin family C2I25_26870 ed14d63de0a074284757c517d43d0c14 209 SUPERFAMILY SSF53335 2 191 4.11E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_26870 ed14d63de0a074284757c517d43d0c14 209 Gene3D G3DSA:3.40.50.150 23 207 3.5E-30 T 14-10-2018 C2I25_26870 ed14d63de0a074284757c517d43d0c14 209 Pfam PF08241 Methyltransferase domain 40 133 1.5E-16 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I25_08095 426e04a4abcf4abfca64d688ebed150c 383 Pfam PF06271 RDD family 215 367 4.4E-13 T 14-10-2018 IPR010432 RDD C2I25_08095 426e04a4abcf4abfca64d688ebed150c 383 PIRSF PIRSF031578 1 383 4.1E-151 T 14-10-2018 IPR021192 Uncharacterised conserved protein UCP031578, VanZ/RDD-type C2I25_08095 426e04a4abcf4abfca64d688ebed150c 383 Pfam PF04892 VanZ like family 49 194 1.1E-22 T 14-10-2018 IPR006976 VanZ-like C2I25_25910 6656796eac773dd7cc5c541c7d97acc9 171 SUPERFAMILY SSF109854 7 165 2.44E-29 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_25910 6656796eac773dd7cc5c541c7d97acc9 171 Pfam PF12867 DinB superfamily 9 160 7.2E-20 T 14-10-2018 IPR024775 DinB-like domain C2I25_25910 6656796eac773dd7cc5c541c7d97acc9 171 Gene3D G3DSA:1.20.120.450 3 165 1.2E-36 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_06110 f5066b9d964cb6080bd5007ff60481c8 217 Pfam PF06161 Protein of unknown function (DUF975) 3 126 2.0E-11 T 14-10-2018 IPR010380 Protein of unknown function DUF975 C2I25_06110 f5066b9d964cb6080bd5007ff60481c8 217 Pfam PF06161 Protein of unknown function (DUF975) 119 207 4.1E-29 T 14-10-2018 IPR010380 Protein of unknown function DUF975 C2I25_15830 b546d9acf7140070c3e0ec096c72089a 114 Gene3D G3DSA:1.10.10.10 6 114 4.8E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15830 b546d9acf7140070c3e0ec096c72089a 114 SUPERFAMILY SSF46785 4 101 9.87E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_15830 b546d9acf7140070c3e0ec096c72089a 114 Pfam PF03551 Transcriptional regulator PadR-like family 20 91 4.9E-23 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_22450 81752b78a81e9806fdc2d11db9d827d8 154 Pfam PF04657 Putative inner membrane exporter, YdcZ 2 135 5.8E-26 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ C2I25_03485 809b890a9429ddad26334bf731e6d24d 128 Pfam PF03994 Domain of Unknown Function (DUF350) 72 126 1.6E-15 T 14-10-2018 IPR007140 Protein of unknown function DUF350 C2I25_03485 809b890a9429ddad26334bf731e6d24d 128 Pfam PF03994 Domain of Unknown Function (DUF350) 7 58 8.2E-11 T 14-10-2018 IPR007140 Protein of unknown function DUF350 C2I25_25215 b984b0e031152d059ca53ee943948dcb 210 Pfam PF07552 Spore Coat Protein X and V domain 152 209 1.7E-23 T 14-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I25_25215 b984b0e031152d059ca53ee943948dcb 210 Pfam PF07552 Spore Coat Protein X and V domain 90 145 1.1E-19 T 14-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I25_14335 1acb7e127fbe41e15f97dda00ed5ca28 159 Pfam PF13302 Acetyltransferase (GNAT) domain 39 137 1.6E-7 T 14-10-2018 IPR000182 GNAT domain C2I25_14335 1acb7e127fbe41e15f97dda00ed5ca28 159 SUPERFAMILY SSF55729 3 142 2.09E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_14335 1acb7e127fbe41e15f97dda00ed5ca28 159 Gene3D G3DSA:3.40.630.30 1 150 4.4E-18 T 14-10-2018 C2I25_01760 7cdf4a68f691066bcb83a936f0b65227 755 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 385 709 4.5E-139 T 14-10-2018 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 C2I25_10340 ce306a9c0bd49404735b2968b130384d 38 Pfam PF13134 Protein of unknown function (DUF3948) 4 37 1.2E-22 T 14-10-2018 IPR025034 Protein of unknown function DUF3948 C2I25_23740 cd9e216b7edeca27785f75c5e1778ae1 101 Gene3D G3DSA:3.30.70.100 1 101 8.5E-40 T 14-10-2018 C2I25_23740 cd9e216b7edeca27785f75c5e1778ae1 101 SUPERFAMILY SSF54909 3 96 3.75E-32 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_23740 cd9e216b7edeca27785f75c5e1778ae1 101 Pfam PF08803 Putative mono-oxygenase ydhR 4 98 2.6E-40 T 14-10-2018 IPR014910 Putative monooxygenase YdhR C2I25_18135 2adaa0f9c7c997890fec41867998f559 66 Pfam PF14038 YqzE-like protein 2 55 1.4E-28 T 14-10-2018 IPR025622 YqzE-like protein C2I25_01350 699bcc05e8d3dd7996d06377ab799674 448 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 17 423 1.5E-143 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_01350 699bcc05e8d3dd7996d06377ab799674 448 Pfam PF05525 Branched-chain amino acid transport protein 12 436 1.1E-153 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_09295 edd9b7270ee4a206e71bdf555d4ea659 192 Gene3D G3DSA:2.60.60.30 19 187 4.1E-72 T 14-10-2018 C2I25_09295 edd9b7270ee4a206e71bdf555d4ea659 192 Pfam PF02342 TerD domain 1 188 8.3E-85 T 14-10-2018 IPR003325 TerD domain C2I25_01460 38fd4728925f75135fc6beaca415a40a 181 Gene3D G3DSA:3.40.50.720 1 107 3.6E-8 T 14-10-2018 C2I25_01460 38fd4728925f75135fc6beaca415a40a 181 SUPERFAMILY SSF51735 3 158 2.13E-8 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_06390 6ba9abb3e90cf45b94cf7f946900b1e1 93 Pfam PF13220 Protein of unknown function (DUF4028) 27 91 2.5E-47 T 14-10-2018 IPR025106 Protein of unknown function DUF4028 C2I25_17510 fd46bdb3970754180df249e61f479a69 40 Pfam PF13215 Protein of unknown function (DUF4023) 1 38 1.1E-20 T 14-10-2018 IPR025097 Protein of unknown function DUF4023 C2I25_23320 db392c540323619237419aeac690d30c 448 Pfam PF02667 Short chain fatty acid transporter 4 447 6.9E-165 T 14-10-2018 IPR006160 Short chain fatty acid transporter AtoE C2I25_08685 09d3505253d66f3b696cb16e3619c317 434 TIGRFAM TIGR00784 citMHS: citrate transporter 1 434 2.8E-204 T 14-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 C2I25_08685 09d3505253d66f3b696cb16e3619c317 434 Pfam PF03600 Citrate transporter 13 380 4.7E-52 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 C2I25_23690 d3fddb14884db079ecdd0f8e57c3e69b 292 Pfam PF02517 CAAX protease self-immunity 144 247 1.4E-9 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_25015 c3bd8594832589649e971a5c3aa87c45 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 3.8E-20 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_25015 c3bd8594832589649e971a5c3aa87c45 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 7.8E-17 T 14-10-2018 IPR012655 Uncharacterised protein YrzI C2I25_10550 e7e7ca4f79c6fc501faeef0cce03ac81 155 Pfam PF14039 YusW-like protein 51 144 2.8E-26 T 14-10-2018 IPR025623 YusW-like protein C2I25_23070 59a6396b81f8b8a127e009e22402ed7b 376 Pfam PF01594 AI-2E family transporter 37 367 2.6E-79 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like C2I25_23200 3564a5baff7be6d0b7f486a128237a01 91 Pfam PF06949 Protein of unknown function (DUF1292) 15 86 5.5E-12 T 14-10-2018 IPR009711 Uncharacterised protein family UPF0473 C2I25_18715 5ea08dd76f7d88bbc9d6cd3fb2d2c490 83 Pfam PF13068 Protein of unknown function (DUF3932) 1 80 3.3E-52 T 14-10-2018 IPR025173 Protein of unknown function DUF3932 C2I25_19265 0086ecb99364253daff98630a722b0f3 110 Pfam PF13077 Protein of unknown function (DUF3909) 1 108 5.7E-69 T 14-10-2018 IPR025073 Protein of unknown function DUF3909 C2I25_04735 a09140694348722c6beeeda9dc27aba3 148 Gene3D G3DSA:1.10.10.10 1 147 1.1E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_04735 a09140694348722c6beeeda9dc27aba3 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.7E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04735 a09140694348722c6beeeda9dc27aba3 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.7E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04735 a09140694348722c6beeeda9dc27aba3 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.7E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04735 a09140694348722c6beeeda9dc27aba3 148 Pfam PF01047 MarR family 40 97 5.7E-19 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04735 a09140694348722c6beeeda9dc27aba3 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I25_04735 a09140694348722c6beeeda9dc27aba3 148 SMART SM00347 33 133 1.9E-29 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I25_04735 a09140694348722c6beeeda9dc27aba3 148 SUPERFAMILY SSF46785 8 145 3.56E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_09535 3d379280571fef0e76aa008d665cbc13 260 Pfam PF10127 Predicted nucleotidyltransferase 1 249 3.6E-96 T 14-10-2018 IPR018775 Nucleotidyltransferase, predicted C2I25_20500 b2fee16cd115387046cb2c1067ef6c72 299 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 4 289 2.0E-146 T 14-10-2018 IPR014215 Dipicolinic acid synthetase subunit A C2I25_20500 b2fee16cd115387046cb2c1067ef6c72 299 Gene3D G3DSA:3.40.50.720 126 272 1.1E-103 T 14-10-2018 C2I25_20500 b2fee16cd115387046cb2c1067ef6c72 299 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 151 289 4.9E-10 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I25_20500 b2fee16cd115387046cb2c1067ef6c72 299 Gene3D G3DSA:3.40.50.720 7 288 1.1E-103 T 14-10-2018 C2I25_20500 b2fee16cd115387046cb2c1067ef6c72 299 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 123 4.1E-29 T 14-10-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal C2I25_20500 b2fee16cd115387046cb2c1067ef6c72 299 SUPERFAMILY SSF51735 131 269 1.45E-17 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I25_10330 0a6c81f6ef08b452c968d91266d5501f 39 Pfam PF13134 Protein of unknown function (DUF3948) 4 38 7.5E-22 T 14-10-2018 IPR025034 Protein of unknown function DUF3948 C2I25_24120 dea34b19b5e08b7b1f471560184268d7 158 Pfam PF10710 Protein of unknown function (DUF2512) 1 140 1.4E-46 T 14-10-2018 IPR019649 Protein of unknown function DUF2512 C2I25_19795 e93b34f273cbb457330daec402b7e495 301 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 27 281 2.4E-61 T 14-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related C2I25_19795 e93b34f273cbb457330daec402b7e495 301 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 3 283 3.3E-143 T 14-10-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG C2I25_06300 e05bd560a152d9476d0370017af67fee 66 Pfam PF14147 Sporulation protein YhaL 4 55 5.6E-29 T 14-10-2018 IPR025428 Sporulation protein YhaL C2I25_02970 d2d51244ec65eb5f84ecfb6a186af6d2 56 Pfam PF13131 Protein of unknown function (DUF3951) 1 52 2.1E-29 T 14-10-2018 IPR025028 Protein of unknown function DUF3951 C2I25_18065 743c870cb2ac02e2a220af0bd91708f2 80 Pfam PF13051 Protein of unknown function (DUF3912) 11 78 9.6E-45 T 14-10-2018 IPR025023 Protein of unknown function DUF3912 C2I25_03025 3d0897df4e8f447fb2e043dc0bdb06a9 91 Pfam PF01313 Bacterial export proteins, family 3 6 75 7.1E-19 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I25_03025 3d0897df4e8f447fb2e043dc0bdb06a9 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.9E-13 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I25_03025 3d0897df4e8f447fb2e043dc0bdb06a9 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.9E-13 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I25_03025 3d0897df4e8f447fb2e043dc0bdb06a9 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.9E-13 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I25_15905 2b6e6eddad52824a392dab24174d6e72 78 Pfam PF13133 Protein of unknown function (DUF3949) 15 75 1.4E-32 T 14-10-2018 IPR025032 Protein of unknown function DUF3949 C2I25_07965 9822a91eba98250dd825613b80947d85 236 Pfam PF13529 Peptidase_C39 like family 48 207 3.8E-41 T 14-10-2018 IPR039564 Peptidase C39-like C2I25_07965 9822a91eba98250dd825613b80947d85 236 Gene3D G3DSA:3.90.70.10 41 236 7.9E-81 T 14-10-2018 C2I25_07965 9822a91eba98250dd825613b80947d85 236 PIRSF PIRSF032442 21 236 3.1E-75 T 14-10-2018 IPR016997 Uncharacterised conserved protein UCP032442 C2I25_19740 de80fe1d7a75a30f79fb92d499960229 165 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 4 164 2.0E-90 T 14-10-2018 IPR020229 Uncharacterised protein YlaL C2I25_16675 b85c388d326ff2283c67097a2af5401e 299 Gene3D G3DSA:1.25.40.10 16 112 5.0E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I25_14980 e17c28814c5df3ee188cd11be95d8174 658 PIRSF PIRSF018968 1 656 4.5E-119 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_14980 e17c28814c5df3ee188cd11be95d8174 658 Pfam PF02687 FtsX-like permease family 87 173 2.0E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_26855 4e89777c5154a975717a68bfd2411ceb 56 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 8 48 8.9E-6 T 14-10-2018 IPR019241 Protein of unknown function DUF2197 C2I25_19745 64b65f5fceaa749b311ff65ae0262baa 95 Hamap MF_01560 UPF0358 protein . 3 93 27.755 T 14-10-2018 IPR009983 Uncharacterised protein family UPF0358 C2I25_19745 64b65f5fceaa749b311ff65ae0262baa 95 Gene3D G3DSA:1.10.287.750 3 93 3.6E-38 T 14-10-2018 IPR036270 UPF0358 superfamily C2I25_19745 64b65f5fceaa749b311ff65ae0262baa 95 Pfam PF07408 Protein of unknown function (DUF1507) 9 91 1.3E-41 T 14-10-2018 IPR009983 Uncharacterised protein family UPF0358 C2I25_19745 64b65f5fceaa749b311ff65ae0262baa 95 SUPERFAMILY SSF140404 6 84 8.5E-37 T 14-10-2018 IPR036270 UPF0358 superfamily C2I25_09290 5271118ae1d2aee1a396d585d32c3962 263 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 32 245 2.8E-80 T 14-10-2018 IPR022493 Integral membrane YkoY C2I25_09290 5271118ae1d2aee1a396d585d32c3962 263 Pfam PF03741 Integral membrane protein TerC family 35 216 7.0E-54 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I25_09290 5271118ae1d2aee1a396d585d32c3962 263 SUPERFAMILY SSF103473 30 243 6.28E-6 T 14-10-2018 IPR036259 MFS transporter superfamily C2I25_08225 f77a21f9a4aa3c3f923bb26871ae9b75 38 Pfam PF13219 Protein of unknown function (DUF4027) 1 36 1.1E-22 T 14-10-2018 IPR025104 Protein of unknown function DUF4027 C2I25_16250 3cae89f891f15a1a7562a5d84eb1b00d 94 Pfam PF13133 Protein of unknown function (DUF3949) 28 88 1.4E-31 T 14-10-2018 IPR025032 Protein of unknown function DUF3949 C2I25_21305 b184fd7a3a61f930866b5a69f8a52612 82 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 4 77 1.1E-23 T 14-10-2018 IPR018680 Protein of unknown function DUF2164 C2I25_16570 e38c3b5e585485314e526869acd1d20f 441 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 418 1.2E-136 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_16570 e38c3b5e585485314e526869acd1d20f 441 Pfam PF05525 Branched-chain amino acid transport protein 9 432 4.3E-143 T 14-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I25_09730 754a9e238dec672e953a3f799059f091 107 Pfam PF00893 Small Multidrug Resistance protein 3 93 6.5E-25 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I25_09730 754a9e238dec672e953a3f799059f091 107 SUPERFAMILY SSF103481 6 105 2.22E-17 T 14-10-2018 C2I25_09730 754a9e238dec672e953a3f799059f091 107 Gene3D G3DSA:1.10.3730.20 1 107 3.2E-32 T 14-10-2018 C2I25_00445 226afac02b2b20f5c815c569ba3f29cd 255 SUPERFAMILY SSF81606 30 228 2.22E-8 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_00445 226afac02b2b20f5c815c569ba3f29cd 255 Gene3D G3DSA:3.60.40.10 5 253 8.1E-8 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I25_19335 3330888f43df5da8fef6bc04ef301d12 253 SUPERFAMILY SSF158560 4 79 4.71E-18 T 14-10-2018 C2I25_04610 e1be166095cc7106c0862ab15dceb30f 60 Pfam PF13052 Protein of unknown function (DUF3913) 2 58 4.0E-44 T 14-10-2018 IPR025024 Protein of unknown function DUF3913 C2I25_12470 f6bc82bab31ad042bd840071e3823218 178 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 81 1.2E-10 T 14-10-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 C2I25_12470 f6bc82bab31ad042bd840071e3823218 178 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 92 2.5E-34 T 14-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 C2I25_12470 f6bc82bab31ad042bd840071e3823218 178 Gene3D G3DSA:1.10.10.1250 2 82 1.2E-33 T 14-10-2018 IPR038087 DNA-directed RNA polymerase subunit delta domain superfamily C2I25_12470 f6bc82bab31ad042bd840071e3823218 178 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 166 14.712 T 14-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 C2I25_12925 ae28cee47086bd899a00ed5b504735ee 399 Pfam PF02687 FtsX-like permease family 305 392 1.3E-14 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_12925 ae28cee47086bd899a00ed5b504735ee 399 Pfam PF12704 MacB-like periplasmic core domain 21 238 6.0E-32 T 14-10-2018 IPR025857 MacB-like periplasmic core domain C2I25_02120 c4a46f15e74f05ed7454b69f7e782ed9 230 Pfam PF02525 Flavodoxin-like fold 25 225 7.4E-41 T 14-10-2018 IPR003680 Flavodoxin-like fold C2I25_02120 c4a46f15e74f05ed7454b69f7e782ed9 230 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 24 230 27.749 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 C2I25_02120 c4a46f15e74f05ed7454b69f7e782ed9 230 Gene3D G3DSA:3.40.50.360 20 230 4.2E-55 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_02120 c4a46f15e74f05ed7454b69f7e782ed9 230 SUPERFAMILY SSF52218 23 230 1.21E-46 T 14-10-2018 IPR029039 Flavoprotein-like superfamily C2I25_26175 0c0dda179bb86596de788dbb72f32447 93 TIGRFAM TIGR03601 B_an_ocin: bacteriocin, heterocycloanthracin/sonorensin family 6 91 1.0E-35 T 14-10-2018 IPR019890 Bacteriocin, heterocycloanthracin/sonorensin family C2I25_07120 7d9a1c6853928c1d447b7f6e427ca27a 399 PIRSF PIRSF037259 1 397 1.5E-118 T 14-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 C2I25_07120 7d9a1c6853928c1d447b7f6e427ca27a 399 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 380 5.2E-104 T 14-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 C2I25_28290 53b0109b85da7cd3ddebfc9d0335748c 70 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 4 19 - T 14-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 C2I25_28290 53b0109b85da7cd3ddebfc9d0335748c 70 Pfam PF01679 Proteolipid membrane potential modulator 2 45 9.9E-12 T 14-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 C2I25_01235 c30c5b6bb59c1ead514643249d42e66f 292 Gene3D G3DSA:3.90.1200.10 104 286 3.7E-6 T 14-10-2018 C2I25_01235 c30c5b6bb59c1ead514643249d42e66f 292 SUPERFAMILY SSF56112 4 274 5.87E-15 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_13675 c1a4e1fc1b1fb05b41c4ee1b6f9505c2 171 Pfam PF13302 Acetyltransferase (GNAT) domain 5 138 4.4E-22 T 14-10-2018 IPR000182 GNAT domain C2I25_13675 c1a4e1fc1b1fb05b41c4ee1b6f9505c2 171 SUPERFAMILY SSF55729 3 162 6.56E-41 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_13675 c1a4e1fc1b1fb05b41c4ee1b6f9505c2 171 Gene3D G3DSA:3.40.630.30 4 169 2.2E-49 T 14-10-2018 C2I25_06675 8112017c575bd8524d75b020af151c8f 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 9 32 3.1E-12 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_06675 8112017c575bd8524d75b020af151c8f 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 11 34 1.7E-11 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_00935 f7bf7fd3956d37ee3e4c613fcc895755 533 SUPERFAMILY SSF53474 57 265 1.55E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_00935 f7bf7fd3956d37ee3e4c613fcc895755 533 Gene3D G3DSA:3.40.50.1820 55 301 1.4E-33 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_21395 7125c48eb10bb5dfd55f861a4322a105 615 PIRSF PIRSF018968 1 612 1.7E-86 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_21395 7125c48eb10bb5dfd55f861a4322a105 615 Pfam PF02687 FtsX-like permease family 78 173 6.9E-14 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_09370 da69ad849dd583db282803e5a5cf8287 123 Pfam PF09350 Domain of unknown function (DUF1992) 7 73 6.5E-24 T 14-10-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain C2I25_05535 f60c9d1d64e2dcc999db50a9460ba11d 58 ProDom PD027277 REPRESSOR COMZ COMG OPERON TRANSCRIPTION POSSIBLE COMPETENCE PROTEIN-RELATED BH2888 REGULATION 1 58 4.0E-26 T 14-10-2018 IPR024558 ComZ C2I25_05535 f60c9d1d64e2dcc999db50a9460ba11d 58 Pfam PF10815 ComZ 3 57 1.7E-32 T 14-10-2018 IPR024558 ComZ C2I25_00400 541f49046b4cf81656d4ab8c808882a1 127 Pfam PF14112 Immunity protein 22 5 125 5.7E-26 T 14-10-2018 IPR025560 Immunity protein 22 C2I25_05400 a51c43a62b7c5a530e9ddfd4a978cf96 123 Hamap MF_01861 UPF0738 protein . 3 123 28.69 T 14-10-2018 IPR020908 Uncharacterised protein family UPF0738 C2I25_13610 79bf0a8d807d5db904a9eeff8fb298c3 338 Gene3D G3DSA:3.40.50.1980 55 324 2.0E-71 T 14-10-2018 C2I25_13610 79bf0a8d807d5db904a9eeff8fb298c3 338 SUPERFAMILY SSF53807 45 323 1.45E-53 T 14-10-2018 C2I25_13610 79bf0a8d807d5db904a9eeff8fb298c3 338 Pfam PF01497 Periplasmic binding protein 64 315 2.2E-37 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I25_13610 79bf0a8d807d5db904a9eeff8fb298c3 338 Gene3D G3DSA:3.40.50.12260 203 313 2.0E-71 T 14-10-2018 C2I25_14605 31d7320e0756df0dc26c5df16ebf5b7a 178 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 33 168 2.8E-37 T 14-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I25_14605 31d7320e0756df0dc26c5df16ebf5b7a 178 SUPERFAMILY SSF49329 29 168 8.38E-40 T 14-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I25_14605 31d7320e0756df0dc26c5df16ebf5b7a 178 Gene3D G3DSA:2.60.40.200 23 174 4.2E-49 T 14-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I25_14395 75cab859bf2728e3d75d8e66977b61fb 127 SUPERFAMILY SSF160631 50 119 4.71E-6 T 14-10-2018 C2I25_08785 95638c51094f859584313533b866888c 216 Gene3D G3DSA:3.40.30.10 28 216 1.5E-50 T 14-10-2018 C2I25_08785 95638c51094f859584313533b866888c 216 Pfam PF13462 Thioredoxin 44 212 8.5E-36 T 14-10-2018 IPR012336 Thioredoxin-like fold C2I25_08785 95638c51094f859584313533b866888c 216 SUPERFAMILY SSF52833 41 211 8.17E-35 T 14-10-2018 IPR036249 Thioredoxin-like superfamily C2I25_22490 608788cbb30b4c20e035ffc9fd5604e4 93 Gene3D G3DSA:3.30.1390.10 58 93 4.5E-5 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like C2I25_13405 b23c21a51b83d85174c59763bab403df 126 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 111 3.8E-25 T 14-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV C2I25_25670 e3fc8dde216b1b4ced4d82b997894b31 121 Pfam PF13789 Domain of unknown function (DUF4181) 12 112 1.9E-17 T 14-10-2018 IPR025441 Protein of unknown function DUF4181 C2I25_15970 8d36a4e62e515f960764fa789bc498da 182 SUPERFAMILY SSF55729 2 163 1.31E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I25_15970 8d36a4e62e515f960764fa789bc498da 182 Gene3D G3DSA:3.40.630.30 5 180 3.8E-25 T 14-10-2018 C2I25_15970 8d36a4e62e515f960764fa789bc498da 182 Pfam PF13302 Acetyltransferase (GNAT) domain 12 152 4.4E-16 T 14-10-2018 IPR000182 GNAT domain C2I25_06705 3c9e4ede97322f403508c46547369f10 255 Pfam PF01925 Sulfite exporter TauE/SafE 13 247 1.7E-42 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I25_12870 8534e23cd3662d386cd3cc1ab85e7d59 276 SUPERFAMILY SSF52266 94 273 2.83E-9 T 14-10-2018 C2I25_12870 8534e23cd3662d386cd3cc1ab85e7d59 276 PIRSF PIRSF030175 2 276 6.9E-110 T 14-10-2018 IPR016948 Uncharacterised conserved protein UCP030175 C2I25_12870 8534e23cd3662d386cd3cc1ab85e7d59 276 Gene3D G3DSA:3.40.50.1110 70 273 1.6E-11 T 14-10-2018 IPR036514 SGNH hydrolase superfamily C2I25_05065 100f68d8a22ddc35613f0031f9c5d30e 413 Pfam PF12698 ABC-2 family transporter protein 19 385 4.3E-51 T 14-10-2018 C2I25_05430 37a4a8f134faa8acd9941c2c3e551258 414 Pfam PF06054 Competence protein CoiA-like family 5 253 4.2E-64 T 14-10-2018 IPR010330 Competence-induced protein CoiA-like C2I25_05430 37a4a8f134faa8acd9941c2c3e551258 414 PIRSF PIRSF007487 4 387 1.5E-105 T 14-10-2018 IPR021176 Competence-induced protein CoiA C2I25_08085 8d783a5999a209969cbb26d321143d4d 95 Gene3D G3DSA:3.30.70.100 1 93 2.3E-6 T 14-10-2018 C2I25_08085 8d783a5999a209969cbb26d321143d4d 95 SUPERFAMILY SSF54909 1 87 2.15E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel C2I25_22625 7933fb748ec59686bfe5afb27a039d2c 118 Pfam PF13471 Transglutaminase-like superfamily 30 107 6.9E-13 T 14-10-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal C2I25_21790 61096eed41a198a6d95bcd3703565e12 141 Pfam PF02681 Divergent PAP2 family 6 135 1.3E-49 T 14-10-2018 IPR003832 Protein of unknown function DUF212 C2I25_14025 5c2139784f01a36a7f5da5e334e23e8f 81 ProDom PD065427 YUSU IG COIL COILED BH3491 1 80 9.0E-41 T 14-10-2018 IPR020393 Uncharacterised protein family YusU C2I25_14025 5c2139784f01a36a7f5da5e334e23e8f 81 Pfam PF10835 Protein of unknown function (DUF2573) 3 80 7.3E-41 T 14-10-2018 IPR020393 Uncharacterised protein family YusU C2I25_00220 c873d76c6a11a5fa6fcdea72ad916ed2 326 PIRSF PIRSF038896 1 311 5.6E-93 T 14-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 C2I25_00220 c873d76c6a11a5fa6fcdea72ad916ed2 326 SUPERFAMILY SSF56281 57 278 4.57E-36 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_00220 c873d76c6a11a5fa6fcdea72ad916ed2 326 Pfam PF12706 Beta-lactamase superfamily domain 76 266 1.0E-38 T 14-10-2018 IPR001279 Metallo-beta-lactamase C2I25_00220 c873d76c6a11a5fa6fcdea72ad916ed2 326 Gene3D G3DSA:3.60.15.10 30 321 9.2E-82 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I25_00740 75e2e417c4cc40a4aa6e73cd22a4e65c 491 Pfam PF04860 Phage portal protein 68 424 1.9E-30 T 14-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein C2I25_00740 75e2e417c4cc40a4aa6e73cd22a4e65c 491 PIRSF PIRSF019260 20 486 1.1E-51 T 14-10-2018 IPR016753 Phage portal protein PBSX family, Firmicutes C2I25_12285 5876085eb101b2170aa2ed1e6bbd937e 224 Pfam PF02163 Peptidase family M50 126 181 1.2E-9 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 C2I25_14095 18405b0f4c8693538091f1e9a84a1793 337 Pfam PF13303 Phosphotransferase system, EIIC 11 333 3.5E-101 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_25360 1d6545d9e03172f92d43cdc396bd0ab3 201 Pfam PF09335 SNARE associated Golgi protein 30 156 1.1E-25 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_13985 219779bf1dc5fb893f1ad7ec24b429c9 271 SUPERFAMILY SSF47473 147 234 6.07E-5 T 14-10-2018 IPR011992 EF-hand domain pair C2I25_25585 cf2df4e1026b3c47859d3eb2b91039ac 128 Pfam PF10990 Protein of unknown function (DUF2809) 32 115 1.7E-30 T 14-10-2018 IPR021257 Protein of unknown function DUF2809 C2I25_10095 9e1fa8a02ed3da00912b99139509ffc0 441 PIRSF PIRSF005353 1 441 1.4E-171 T 14-10-2018 IPR026033 Purine permease PbuG-like C2I25_10095 9e1fa8a02ed3da00912b99139509ffc0 441 Pfam PF00860 Permease family 17 402 2.7E-41 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I25_01640 8f6539c9932996dd8050dca76d19b31b 65 Pfam PF13314 Domain of unknown function (DUF4083) 7 63 4.1E-29 T 14-10-2018 IPR025143 Protein of unknown function DUF4083 C2I25_01955 c3f1e84812bc5e3ba04be091b1129520 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 300 2.3E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I25_24185 f0f65c0e444b42e14c5fb536ae8c6d83 210 Pfam PF02698 DUF218 domain 48 177 4.8E-27 T 14-10-2018 IPR003848 Domain of unknown function DUF218 C2I25_10435 355679da203a35a5356761835d61d103 118 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 3 114 2.5E-14 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_10435 355679da203a35a5356761835d61d103 118 SUPERFAMILY SSF159121 31 114 2.75E-19 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_10435 355679da203a35a5356761835d61d103 118 Pfam PF06486 Protein of unknown function (DUF1093) 33 102 4.4E-12 T 14-10-2018 IPR006542 Protein of unknown function DUF1093 C2I25_10435 355679da203a35a5356761835d61d103 118 Gene3D G3DSA:2.40.50.480 29 115 5.4E-19 T 14-10-2018 IPR036166 YxeA-like superfamily C2I25_28440 a51e6cb4330aecfcea21d3be68019483 90 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 2 90 3.8E-49 T 14-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU C2I25_28440 a51e6cb4330aecfcea21d3be68019483 90 Pfam PF14122 YokU-like protein, putative antitoxin 2 88 4.1E-44 T 14-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU C2I25_28440 a51e6cb4330aecfcea21d3be68019483 90 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 49 4.4E-12 T 14-10-2018 IPR022453 Zinc finger, MqsA-type C2I25_16655 f45d83c07b2e8b6ee1b0682bf2fa7481 289 Pfam PF13349 Putative adhesin 40 287 1.6E-31 T 14-10-2018 IPR025164 Putative adhesin C2I25_16955 0fbfed74bf913cb93688c2adde7889a2 277 Pfam PF01578 Cytochrome C assembly protein 71 270 4.5E-27 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 C2I25_26510 103b01798f482e739edd352f0a390c32 514 Pfam PF13032 Domain of unknown function (DUF3893) 377 484 6.2E-19 T 14-10-2018 IPR024996 Domain of unknown function DUF3893 C2I25_10270 0b5fb75dfafe0a93d1119caf7d4eb882 337 SUPERFAMILY SSF89392 28 205 3.14E-17 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX C2I25_10270 0b5fb75dfafe0a93d1119caf7d4eb882 337 Gene3D G3DSA:2.50.20.10 23 217 5.0E-11 T 14-10-2018 C2I25_19820 6736bd4bef2749ebd1b11f655525e532 81 Pfam PF14003 YlbE-like protein 14 73 4.4E-27 T 14-10-2018 IPR025613 YlbE-like protein C2I25_10120 f330076d31d0c747149315dd31869777 63 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 1 63 0.003 T 14-10-2018 C2I25_10120 f330076d31d0c747149315dd31869777 63 Pfam PF14146 Domain of unknown function (DUF4305) 18 54 2.6E-14 T 14-10-2018 IPR025426 Protein of unknown function DUF4305 C2I25_05985 d1e7046f58a94d6a45f887226181bce4 117 Pfam PF14470 Bacterial PH domain 12 108 3.3E-19 T 14-10-2018 IPR039519 YokE-like, PH domain C2I25_02475 ba406eaaa81a41f39c7e931fbc03a537 234 Pfam PF01522 Polysaccharide deacetylase 42 147 4.1E-29 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I25_02475 ba406eaaa81a41f39c7e931fbc03a537 234 SUPERFAMILY SSF88713 7 229 2.3E-50 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I25_02475 ba406eaaa81a41f39c7e931fbc03a537 234 Gene3D G3DSA:3.20.20.370 25 234 2.9E-53 T 14-10-2018 C2I25_13385 5a3ddd5618fadc8a2d4acb79e6359edb 143 Pfam PF14275 Domain of unknown function (DUF4362) 30 122 3.7E-37 T 14-10-2018 IPR025372 Protein of unknown function DUF4362 C2I25_27910 5ffe7f59a4e8c11205c6f5d10454c2fb 298 Pfam PF02517 CAAX protease self-immunity 141 228 2.6E-8 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_21990 a978fed2b48c8408d0e893203d5ccc88 788 Pfam PF11958 Domain of unknown function (DUF3472) 105 263 1.2E-27 T 14-10-2018 IPR021862 Protein of unknown function DUF3472 C2I25_21990 a978fed2b48c8408d0e893203d5ccc88 788 Pfam PF03272 Putative mucin or carbohydrate-binding module 527 645 1.7E-25 T 14-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain C2I25_21990 a978fed2b48c8408d0e893203d5ccc88 788 Pfam PF03272 Putative mucin or carbohydrate-binding module 666 784 1.6E-24 T 14-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain C2I25_21990 a978fed2b48c8408d0e893203d5ccc88 788 Pfam PF03272 Putative mucin or carbohydrate-binding module 393 506 5.2E-28 T 14-10-2018 IPR004954 Putative mucin/carbohydrate-binding domain C2I25_07635 90b0c34955a5354e8033006dcb05a7b3 284 SUPERFAMILY SSF52151 5 275 2.62E-46 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I25_07635 90b0c34955a5354e8033006dcb05a7b3 284 Pfam PF01734 Patatin-like phospholipase 7 171 2.4E-19 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I25_07635 90b0c34955a5354e8033006dcb05a7b3 284 Gene3D G3DSA:3.40.1090.10 3 84 1.1E-11 T 14-10-2018 C2I25_27290 9b0cc5b374fedf5251246b90f0f3fdd2 406 Gene3D G3DSA:1.20.1170.10 268 405 2.1E-29 T 14-10-2018 C2I25_27290 9b0cc5b374fedf5251246b90f0f3fdd2 406 Gene3D G3DSA:1.20.1170.10 41 267 6.7E-69 T 14-10-2018 C2I25_27290 9b0cc5b374fedf5251246b90f0f3fdd2 406 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 45 230 4.6E-66 T 14-10-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 C2I25_27290 9b0cc5b374fedf5251246b90f0f3fdd2 406 SUPERFAMILY SSF58100 37 400 5.75E-84 T 14-10-2018 C2I25_14990 bc236db418405e878d7de3268dc36ecd 651 Pfam PF02687 FtsX-like permease family 84 168 1.4E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I25_14990 bc236db418405e878d7de3268dc36ecd 651 PIRSF PIRSF018968 1 649 6.0E-123 T 14-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I25_22565 4621c26db5845a26d308163cb7741d6e 42 Pfam PF13124 Protein of unknown function (DUF3963) 1 40 3.9E-31 T 14-10-2018 IPR025011 Protein of unknown function DUF3963 C2I25_15200 9f5c9f5ad907c99db6e5acdcd4698fc2 71 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 3.1E-22 T 14-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I25_19380 039b0e4f1d0e767cccb5cb1e9af04c65 143 Pfam PF13162 Protein of unknown function (DUF3997) 28 132 3.2E-39 T 14-10-2018 IPR025059 Protein of unknown function DUF3997 C2I25_03305 37020e4c0f6d30f8af80845fbd898488 221 Gene3D G3DSA:3.30.240.20 75 146 2.8E-20 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_03305 37020e4c0f6d30f8af80845fbd898488 221 Gene3D G3DSA:3.30.240.20 162 221 1.1E-16 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I25_03305 37020e4c0f6d30f8af80845fbd898488 221 Pfam PF04239 Protein of unknown function (DUF421) 82 197 2.9E-32 T 14-10-2018 IPR007353 Protein of unknown function DUF421 C2I25_01410 7cc679203030c9d8b97085d4b1c52308 171 Pfam PF03061 Thioesterase superfamily 31 103 1.5E-12 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I25_01410 7cc679203030c9d8b97085d4b1c52308 171 Gene3D G3DSA:3.10.129.10 1 171 1.5E-58 T 14-10-2018 C2I25_01410 7cc679203030c9d8b97085d4b1c52308 171 SUPERFAMILY SSF54637 11 159 3.38E-43 T 14-10-2018 IPR029069 HotDog domain superfamily C2I25_13950 05a2c58c048a456b072445c52ed67d38 46 Pfam PF13153 Protein of unknown function (DUF3985) 1 44 6.6E-27 T 14-10-2018 IPR025053 Protein of unknown function DUF3985 C2I25_24480 512a5e0c7397ca7af957e633217b919e 387 Pfam PF01882 Protein of unknown function DUF58 213 292 2.2E-12 T 14-10-2018 IPR002881 Domain of unknown function DUF58 C2I25_08030 25e71d386c781a77a74160487da7781a 515 Gene3D G3DSA:3.40.50.880 36 219 1.0E-5 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_08030 25e71d386c781a77a74160487da7781a 515 SUPERFAMILY SSF52317 40 294 2.98E-10 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I25_15520 0699c608f39253b02b136d4fbbf17310 340 Pfam PF04235 Protein of unknown function (DUF418) 165 333 1.2E-30 T 14-10-2018 IPR007349 Domain of unknown function DUF418 C2I25_03345 630ac4a1b1cadecc373900358562be80 209 Pfam PF04116 Fatty acid hydroxylase superfamily 42 183 4.8E-18 T 14-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 C2I25_20890 d6858113d10be7cee9b40be871c334ab 271 Gene3D G3DSA:1.20.1080.10 4 262 1.5E-81 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I25_20890 d6858113d10be7cee9b40be871c334ab 271 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 161 171 - T 14-10-2018 IPR024002 Formate/nitrite transporter, conserved site C2I25_20890 d6858113d10be7cee9b40be871c334ab 271 Pfam PF01226 Formate/nitrite transporter 9 248 2.7E-75 T 14-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 C2I25_03470 0ddb2035c407cb1731aaa23aa31e1b8b 46 Pfam PF13040 Fur-regulated basic protein B 2 39 1.1E-14 T 14-10-2018 IPR025004 Transcriptional regulatory protein SenN/SenS C2I25_13145 7959dabb39dc0afbe1377661d26218b2 385 Pfam PF01757 Acyltransferase family 10 343 2.9E-29 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I25_08515 87c676608429d8e5d511d473dab7b71a 184 SUPERFAMILY SSF53335 37 149 1.33E-8 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_08515 87c676608429d8e5d511d473dab7b71a 184 Gene3D G3DSA:3.40.50.150 10 169 8.5E-11 T 14-10-2018 C2I25_24090 4e7908df27064cb87d618824cd1ad972 113 Pfam PF08863 YolD-like protein 21 112 1.8E-21 T 14-10-2018 IPR014962 YolD-like protein C2I25_05775 75364d25ae22bcd6d691c0656449eaf3 210 Pfam PF00395 S-layer homology domain 90 134 3.5E-14 T 14-10-2018 IPR001119 S-layer homology domain C2I25_05775 75364d25ae22bcd6d691c0656449eaf3 210 Pfam PF00395 S-layer homology domain 30 72 8.7E-8 T 14-10-2018 IPR001119 S-layer homology domain C2I25_05775 75364d25ae22bcd6d691c0656449eaf3 210 Pfam PF00395 S-layer homology domain 150 193 1.2E-9 T 14-10-2018 IPR001119 S-layer homology domain C2I25_24855 bf13be51108450a1c776de7ee44a78f0 220 Pfam PF12952 Domain of unknown function (DUF3841) 2 196 4.0E-47 T 14-10-2018 IPR024211 Protein of unknown function DUF3841 C2I25_21025 96a93d9c8211ef040de46ea798fe8f40 267 Pfam PF13349 Putative adhesin 46 265 1.4E-27 T 14-10-2018 IPR025164 Putative adhesin C2I25_00330 ab717507c1c1824b28337738905b5527 161 Pfam PF11188 Protein of unknown function (DUF2975) 33 161 3.6E-35 T 14-10-2018 IPR021354 Protein of unknown function DUF2975 C2I25_25300 f4837fd4ab84ad95ff85e4efe3e80dbb 76 SUPERFAMILY SSF46785 14 75 8.73E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_11590 e0013837f95688c6f9e34bb8cb09e93c 333 Pfam PF14175 YaaC-like Protein 10 321 2.1E-112 T 14-10-2018 IPR026988 YaaC-like protein C2I25_22690 d35afb32143f634760de96840de303bd 188 SUPERFAMILY SSF52266 1 186 2.44E-43 T 14-10-2018 C2I25_22690 d35afb32143f634760de96840de303bd 188 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 174 7.2E-27 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain C2I25_22690 d35afb32143f634760de96840de303bd 188 Gene3D G3DSA:3.40.50.1110 1 186 4.1E-46 T 14-10-2018 IPR036514 SGNH hydrolase superfamily C2I25_00355 551ce2029111bce04522087f21baf40f 479 Pfam PF02447 GntP family permease 65 270 1.5E-8 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I25_13750 6454b0873de7c8aee0c89523b7f7a0a5 306 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 87 123 2.0E-11 T 14-10-2018 IPR023849 Uncharacterised domain CHP03934, TQXA C2I25_22455 959dc96b8879265580f2c6f34d66f5a7 140 Pfam PF04657 Putative inner membrane exporter, YdcZ 2 136 2.1E-30 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ C2I25_00210 87bd4788499ee459397be6487ae6ef93 153 SUPERFAMILY SSF49764 30 145 1.33E-27 T 14-10-2018 IPR008978 HSP20-like chaperone C2I25_00210 87bd4788499ee459397be6487ae6ef93 153 Gene3D G3DSA:2.60.40.790 6 151 1.2E-28 T 14-10-2018 IPR008978 HSP20-like chaperone C2I25_00210 87bd4788499ee459397be6487ae6ef93 153 Pfam PF00011 Hsp20/alpha crystallin family 57 147 1.1E-15 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain C2I25_27075 023d67fec4c2705c14add7fda0b1943e 45 Pfam PF13104 Protein of unknown function (DUF3956) 1 45 2.0E-33 T 14-10-2018 IPR025225 Protein of unknown function DUF3956 C2I25_22255 cb5f2e109acfbc64246aac33f9cd6829 310 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 5 284 5.3E-52 T 14-10-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 C2I25_08080 ecc452a75ec45ea9d192a417e3921e8e 270 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 270 17.237 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I25_08080 ecc452a75ec45ea9d192a417e3921e8e 270 Pfam PF02673 Bacitracin resistance protein BacA 11 265 1.0E-75 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I25_08160 b92b7baf5a4211a9e27837b042a776ce 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 303 8.0E-53 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I25_23550 b7c423b97defecd8ef19c2828f1f7b91 380 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 343 375 2.7E-4 T 14-10-2018 C2I25_26295 e755d2da37fa2945deac6ee3016ad183 208 Pfam PF04892 VanZ like family 42 183 3.1E-26 T 14-10-2018 IPR006976 VanZ-like C2I25_00865 5e0b221472cb1e40122abe28a438dcc8 171 Pfam PF01381 Helix-turn-helix 9 42 4.1E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I25_00865 5e0b221472cb1e40122abe28a438dcc8 171 SUPERFAMILY SSF47413 1 58 1.53E-8 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I25_00865 5e0b221472cb1e40122abe28a438dcc8 171 Gene3D G3DSA:1.10.260.40 1 62 1.7E-7 T 14-10-2018 C2I25_13400 7d469a96a6118d071f7436a5809913b0 149 Pfam PF14101 Domain of unknown function (DUF4275) 1 145 1.1E-66 T 14-10-2018 IPR025454 Protein of unknown function DUF4275 C2I25_01675 290d91d7bde8512a796fc7004e11711b 204 Pfam PF01810 LysE type translocator 15 198 5.1E-29 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I25_14855 30edfdb8cb76c8ac16072a300a9cc196 240 Gene3D G3DSA:3.40.50.1820 7 240 2.8E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_14855 30edfdb8cb76c8ac16072a300a9cc196 240 Pfam PF01764 Lipase (class 3) 66 196 1.7E-29 T 14-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 C2I25_14855 30edfdb8cb76c8ac16072a300a9cc196 240 SUPERFAMILY SSF53474 6 218 5.2E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I25_12175 0e77b3ff1ba0ea67eea00f0790a59a94 330 Pfam PF12679 ABC-2 family transporter protein 6 328 7.0E-25 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I25_03140 9a7ce786847a25d979e80cac258e4bfb 99 Pfam PF02049 Flagellar hook-basal body complex protein FliE 31 99 2.1E-13 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 C2I25_27040 a7f71ba6dc076340f8454419cf785472 43 Pfam PF13021 Domain of unknown function (DUF3885) 1 38 1.4E-19 T 14-10-2018 IPR024976 Domain of unknown function DUF3885 C2I25_13330 254f49f0b25b84af84fabe0a0cf70934 571 Gene3D G3DSA:3.40.50.300 318 570 4.2E-93 T 14-10-2018 C2I25_13330 254f49f0b25b84af84fabe0a0cf70934 571 SUPERFAMILY SSF90123 3 316 3.66E-80 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_13330 254f49f0b25b84af84fabe0a0cf70934 571 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I25_13330 254f49f0b25b84af84fabe0a0cf70934 571 Pfam PF00005 ABC transporter 349 498 4.1E-37 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I25_13330 254f49f0b25b84af84fabe0a0cf70934 571 Gene3D G3DSA:1.20.1560.10 1 315 3.6E-84 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I25_13330 254f49f0b25b84af84fabe0a0cf70934 571 SMART SM00382 358 544 7.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain C2I25_13330 254f49f0b25b84af84fabe0a0cf70934 571 SUPERFAMILY SSF52540 322 569 5.65E-93 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I25_13330 254f49f0b25b84af84fabe0a0cf70934 571 Pfam PF00664 ABC transporter transmembrane region 17 286 1.9E-56 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I25_06765 caf07a16100a87092139ae35466b03ae 461 TIGRFAM TIGR03236 dnd_assoc_1: DNA phosphorothioation-dependent restriction protein DptG 101 460 9.0E-60 T 14-10-2018 IPR017645 DNA phosphorothioation-dependent restriction protein DptG C2I25_28360 3b08d261b0bb72984e54dc302aeb2aad 191 SUPERFAMILY SSF49842 47 165 1.62E-18 T 14-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I25_28360 3b08d261b0bb72984e54dc302aeb2aad 191 Gene3D G3DSA:2.60.120.40 44 184 2.3E-9 T 14-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I25_24850 76aca88a793d370d9f131c9c6b63216f 223 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 183 3.1E-69 T 14-10-2018 IPR022301 Integral membrane protein YjbE C2I25_24850 76aca88a793d370d9f131c9c6b63216f 223 Pfam PF03741 Integral membrane protein TerC family 14 182 2.8E-45 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I25_18835 ddef03a2967aa5bad0d5edf86ce6cab1 457 Pfam PF03553 Na+/H+ antiporter family 154 444 3.3E-57 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I25_18835 ddef03a2967aa5bad0d5edf86ce6cab1 457 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 448 6.0E-131 T 14-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 C2I25_26505 102fc3966dbbd774c5902f01ec6351ca 255 Pfam PF13105 Protein of unknown function (DUF3959) 9 251 2.4E-139 T 14-10-2018 IPR025080 Protein of unknown function DUF3959 C2I25_22120 694ab69ac9083ef71cb6c2d31f57bdad 212 Pfam PF04892 VanZ like family 48 161 1.4E-20 T 14-10-2018 IPR006976 VanZ-like C2I25_05820 e3d0e777437fdfac310bf26c77b0eadd 121 Gene3D G3DSA:3.10.180.10 3 121 1.0E-11 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_05820 e3d0e777437fdfac310bf26c77b0eadd 121 SUPERFAMILY SSF54593 1 119 7.19E-14 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_01395 ca212debe518daf83d06746460811fc8 152 Pfam PF07875 Coat F domain 83 140 3.2E-8 T 14-10-2018 IPR012851 Spore coat protein CotF-like C2I25_11555 37107fa7c9f8d0c5f8ac924210d631ad 183 Pfam PF12677 Domain of unknown function (DUF3797) 54 107 5.5E-25 T 14-10-2018 IPR024256 Domain of unknown function DUF3797 C2I25_11555 37107fa7c9f8d0c5f8ac924210d631ad 183 Pfam PF04545 Sigma-70, region 4 136 168 1.3E-6 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I25_23170 cb0f0f25eb3c9ffb0453ce01b239caa2 552 Pfam PF16949 Putative ATP-binding cassette 68 448 1.2E-14 T 14-10-2018 IPR031599 Putative ATP-binding cassette C2I25_25470 1c524c2b7602318461bea93fa7e69607 62 Pfam PF13209 Protein of unknown function (DUF4017) 1 60 3.1E-37 T 14-10-2018 IPR025090 Protein of unknown function DUF4017 C2I25_23725 dd948bc290748d11234b1d7c250a6688 132 Pfam PF07485 Domain of Unknown Function (DUF1259) 14 130 1.1E-30 T 14-10-2018 IPR011094 Uncharacterised protein family, LppY/LpqO C2I25_05550 8eb6da844757d209f1142c1570f504e9 60 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 1.7E-21 T 14-10-2018 IPR021324 Protein of unknown function DUF2929 C2I25_05190 069c0d7799c76d4b363a2ec1332a2387 119 Pfam PF13221 Protein of unknown function (DUF4029) 22 117 4.4E-57 T 14-10-2018 IPR025107 Protein of unknown function DUF4029 C2I25_24495 849e4d81d4541da118dd73c2c2681a8b 178 Pfam PF11193 Protein of unknown function (DUF2812) 15 124 1.8E-27 T 14-10-2018 IPR021359 Protein of unknown function DUF2812 C2I25_14660 3529250a8bcf57da1442649b195f9c8f 139 Gene3D G3DSA:3.30.310.100 5 108 2.1E-31 T 14-10-2018 IPR036491 YugN-like superfamily C2I25_14660 3529250a8bcf57da1442649b195f9c8f 139 Pfam PF08868 YugN-like family 5 134 4.3E-54 T 14-10-2018 IPR014967 Uncharacterised protein family, YugN-like C2I25_14660 3529250a8bcf57da1442649b195f9c8f 139 SUPERFAMILY SSF160755 4 135 3.4E-37 T 14-10-2018 IPR036491 YugN-like superfamily C2I25_07200 65b2f110374f424a0a97013822095f15 133 Pfam PF12680 SnoaL-like domain 13 117 2.8E-9 T 14-10-2018 IPR037401 SnoaL-like domain C2I25_07200 65b2f110374f424a0a97013822095f15 133 Gene3D G3DSA:3.10.450.50 1 133 1.2E-37 T 14-10-2018 C2I25_07200 65b2f110374f424a0a97013822095f15 133 SUPERFAMILY SSF54427 3 131 1.03E-32 T 14-10-2018 IPR032710 NTF2-like domain superfamily C2I25_06930 b86e2f13123531099475f10d9b727264 464 Pfam PF13425 O-antigen ligase like membrane protein 10 462 7.6E-130 T 14-10-2018 C2I25_19170 d91235549e8ed06e4c6212e7b7b79bed 31 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 6 28 3.2E-12 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_19170 d91235549e8ed06e4c6212e7b7b79bed 31 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 7 30 1.4E-11 T 14-10-2018 IPR010070 Sporulation protein YjcZ-like C2I25_25840 19b40af7ebdf61b9ea3920130d1ffdba 198 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 4 154 1.3E-50 T 14-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 C2I25_25840 19b40af7ebdf61b9ea3920130d1ffdba 198 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 25 152 2.1E-16 T 14-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like C2I25_01345 aeaad6bf5f706c08cf6843959f824387 109 Pfam PF01588 Putative tRNA binding domain 12 107 2.9E-15 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 C2I25_01345 aeaad6bf5f706c08cf6843959f824387 109 Gene3D G3DSA:2.40.50.140 1 109 1.0E-28 T 14-10-2018 C2I25_01345 aeaad6bf5f706c08cf6843959f824387 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 108 6.6E-47 T 14-10-2018 IPR008231 Probable chaperone CsaA C2I25_01345 aeaad6bf5f706c08cf6843959f824387 109 SUPERFAMILY SSF50249 2 108 5.14E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I25_10115 4c320ec5480401e1e92c068f5ce7ac55 249 Pfam PF02517 CAAX protease self-immunity 130 216 9.1E-18 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_11310 1d838c4d1ba32cd97a7dcdc6e28df551 119 Pfam PF04977 Septum formation initiator 44 118 2.3E-18 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC C2I25_20865 5b790d8c3dec859373acaeb9b3904e9d 100 Gene3D G3DSA:1.20.58.1000 1 99 6.1E-38 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily C2I25_20865 5b790d8c3dec859373acaeb9b3904e9d 100 Pfam PF02583 Metal-sensitive transcriptional repressor 16 95 2.3E-32 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 C2I25_06260 e3e3138e6ee0467294d5b239827817bd 113 SUPERFAMILY SSF46785 13 103 2.44E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I25_06260 e3e3138e6ee0467294d5b239827817bd 113 Pfam PF03551 Transcriptional regulator PadR-like family 17 91 9.2E-26 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I25_06260 e3e3138e6ee0467294d5b239827817bd 113 Gene3D G3DSA:1.10.10.10 4 111 1.2E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I25_15350 25ce3b00d6d79421e52087024b0c8140 861 Pfam PF13731 WxL domain surface cell wall-binding 721 807 1.1E-6 T 14-10-2018 IPR027994 WxL domain C2I25_15770 dc71cbc47f34a9e855a21698ed33c198 103 Pfam PF03413 Peptidase propeptide and YPEB domain 30 100 3.5E-9 T 14-10-2018 IPR025711 PepSY domain C2I25_20225 12735c161ce06f6a7e5033384d4a5747 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 8.7E-37 T 14-10-2018 IPR005531 Alkaline shock protein Asp23 C2I25_06160 1716d24b1a4ab2097dc28b58d83be45a 235 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 1 234 8.0E-117 T 14-10-2018 C2I25_06160 1716d24b1a4ab2097dc28b58d83be45a 235 Pfam PF12787 EcsC protein family 7 232 6.7E-77 T 14-10-2018 IPR024787 EcsC protein C2I25_07545 38a032aeba6357b36b2079bc6e4114b0 71 Pfam PF07561 Domain of Unknown Function (DUF1540) 4 67 1.8E-13 T 14-10-2018 IPR011437 Domain of unknown function DUF1540 C2I25_15195 523cdf45d252882ef0649753f84ac614 345 Pfam PF02698 DUF218 domain 165 314 3.2E-31 T 14-10-2018 IPR003848 Domain of unknown function DUF218 C2I25_24345 e06d79cb2d307fd6606a63a9182f3f79 148 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 144 3.6E-41 T 14-10-2018 IPR003791 Protein of unknown function UPF0178 C2I25_24345 e06d79cb2d307fd6606a63a9182f3f79 148 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 29.849 T 14-10-2018 IPR003791 Protein of unknown function UPF0178 C2I25_26990 12f95d516eb067a34b987ba1f4236106 186 Gene3D G3DSA:3.40.50.150 17 168 7.9E-11 T 14-10-2018 C2I25_26990 12f95d516eb067a34b987ba1f4236106 186 SUPERFAMILY SSF53335 43 153 7.64E-10 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I25_10650 438c3ed49f91b7e758946638d33b78ce 168 Pfam PF07681 DoxX 16 114 1.2E-10 T 14-10-2018 IPR032808 DoxX family C2I25_03890 b0427d3f03a5363974fd1049541f6141 297 Pfam PF14045 YIEGIA protein 8 288 5.1E-124 T 14-10-2018 IPR025918 YIEGIA protein C2I25_03890 b0427d3f03a5363974fd1049541f6141 297 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 1 281 1.0E-139 T 14-10-2018 C2I25_00830 18e41ab56295b3d2aa2ebe38cf4fc08c 227 Pfam PF01391 Collagen triple helix repeat (20 copies) 30 78 8.2E-9 T 14-10-2018 IPR008160 Collagen triple helix repeat C2I25_14380 0a7cc3b6dd608c9208432f91e49937f3 214 Pfam PF14137 Domain of unknown function (DUF4304) 20 154 4.6E-37 T 14-10-2018 IPR025412 Protein of unknown function DUF4304 C2I25_13505 c2f6306a249d40571cbabd6104d7b76f 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 9.2E-22 T 14-10-2018 IPR012452 Protein of unknown function DUF1657 C2I25_25525 66f14647cd68686c827b1f7703e1cdca 281 Pfam PF02517 CAAX protease self-immunity 125 226 3.5E-12 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_22550 3a681720373923e22353fed25c59b861 85 Pfam PF13124 Protein of unknown function (DUF3963) 44 83 3.5E-29 T 14-10-2018 IPR025011 Protein of unknown function DUF3963 C2I25_22770 22b3e681bffeb9ce48295abbe6242123 439 Pfam PF03222 Tryptophan/tyrosine permease family 40 417 2.6E-17 T 14-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 C2I25_12955 b64fb495a2f5339ccc887f2fd7b2b7be 74 Pfam PF07872 Protein of unknown function (DUF1659) 8 51 3.1E-16 T 14-10-2018 IPR012454 Protein of unknown function DUF1659 C2I25_25855 817f75acacc0279e5fc33efb955d835c 351 Pfam PF06081 Aromatic acid exporter family member 1 10 148 1.4E-36 T 14-10-2018 IPR010343 Aromatic acid exporter family member 1 C2I25_18975 4449a4d0b33270e3c84559d6d3baaf17 44 Pfam PF13072 Protein of unknown function (DUF3936) 1 37 1.9E-22 T 14-10-2018 IPR025177 Cell division inhibitor MciZ C2I25_03545 5f7930494f18197b893fae135fd25de6 387 Pfam PF04235 Protein of unknown function (DUF418) 217 376 3.6E-38 T 14-10-2018 IPR007349 Domain of unknown function DUF418 C2I25_00735 e0a5ef7685cdfe1688459ceb9f789253 172 Pfam PF04233 Phage Mu protein F like protein 61 169 1.6E-20 T 14-10-2018 IPR006528 Phage head morphogenesis domain C2I25_00735 e0a5ef7685cdfe1688459ceb9f789253 172 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 64 170 2.4E-19 T 14-10-2018 IPR006528 Phage head morphogenesis domain C2I25_00370 7db1141acad055656bdaaae45398903e 191 Pfam PF06042 Nucleotidyltransferase 25 186 1.6E-55 T 14-10-2018 IPR009267 Putative nucleotidyltransferase C2I25_08535 a548c43539ef69f2cf219df4293061b2 160 Pfam PF07849 Protein of unknown function (DUF1641) 121 155 2.4E-11 T 14-10-2018 IPR012440 Protein of unknown function DUF1641 C2I25_17790 ae2674e8d62015dcc024d7c592020cee 47 Pfam PF14006 YqzL-like protein 3 46 3.2E-20 T 14-10-2018 IPR025617 YqzL-like protein C2I25_03125 73a1bcea603e339640fef31465aeec67 229 Pfam PF02108 Flagellar assembly protein FliH 85 198 5.8E-8 T 14-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE C2I25_09825 3c8ddf1e5df2db8e82e999130ac69e07 382 Pfam PF01757 Acyltransferase family 8 338 4.3E-38 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I25_09115 30e3874fa6b545af99a335b5dd5ec7d0 113 Pfam PF13108 Protein of unknown function (DUF3969) 9 111 4.7E-36 T 14-10-2018 IPR025083 Protein of unknown function DUF3969 C2I25_20125 07aa40b723dd434cd85f0dce44569e97 393 Pfam PF07007 Lysozyme inhibitor LprI 302 387 7.2E-12 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal C2I25_18545 05511a1d79f916e53b1506b98986cc25 186 SMART SM00496 99 115 5.4 T 14-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 C2I25_18545 05511a1d79f916e53b1506b98986cc25 186 SMART SM00496 82 98 9.2 T 14-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 C2I25_18545 05511a1d79f916e53b1506b98986cc25 186 SMART SM00496 28 44 390.0 T 14-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 C2I25_11450 ce00eae14573951d24ef410d22af984e 278 Pfam PF04468 PSP1 C-terminal conserved region 64 149 9.5E-33 T 14-10-2018 IPR007557 PSP1, C-terminal C2I25_01095 427285f6c979518233e033b0ff668027 226 Pfam PF12207 Domain of unknown function (DUF3600) 65 224 4.7E-79 T 14-10-2018 IPR022019 Domain of unknown function DUF3600 C2I25_01095 427285f6c979518233e033b0ff668027 226 Gene3D G3DSA:1.10.3950.10 69 226 1.3E-68 T 14-10-2018 IPR038267 Putative ECF-type sigma factor negative effector C2I25_20570 b1c45f2fcd0db5bdf11204e456749945 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 288 1.6E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I25_10580 cea22fcf2c3d69c548b4e358b223be60 71 Pfam PF13131 Protein of unknown function (DUF3951) 4 52 1.2E-24 T 14-10-2018 IPR025028 Protein of unknown function DUF3951 C2I25_18235 c15ec5a5ab5d240826ff59383c09a95d 85 Pfam PF13126 Protein of unknown function (DUF3975) 1 80 3.5E-46 T 14-10-2018 IPR025015 Protein of unknown function DUF3975 C2I25_01435 324ef07ec673c03a80a74144c732c96e 200 Pfam PF09335 SNARE associated Golgi protein 30 156 1.8E-24 T 14-10-2018 IPR032816 SNARE associated Golgi protein C2I25_07265 93ba91facac3a840ebd5b7f2127306de 114 Pfam PF13157 Protein of unknown function (DUF3992) 21 109 1.5E-34 T 14-10-2018 IPR025055 Protein of unknown function DUF3992 C2I25_23950 e7fbec86f9d0ad2afbdb7a84caadddda 868 Hamap MF_01871 UPF0753 protein . 19 868 24.263 T 14-10-2018 IPR018752 Uncharacterised protein family UPF0753 C2I25_23950 e7fbec86f9d0ad2afbdb7a84caadddda 868 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 24 854 2.0E-268 T 14-10-2018 IPR018752 Uncharacterised protein family UPF0753 C2I25_19875 94f2a0cd1d3a7613de875591280fa206 166 Pfam PF02620 Uncharacterized ACR, COG1399 56 163 5.3E-22 T 14-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD C2I25_23455 33dbde9d5f9b13ea3cb6fe6c50645a3e 63 Pfam PF04070 Domain of unknown function (DUF378) 2 56 1.1E-15 T 14-10-2018 IPR007211 Protein of unknown function DUF378 C2I25_25985 b9277b6b832c79020d81e29bce78981b 122 Pfam PF13788 Domain of unknown function (DUF4180) 10 118 3.9E-43 T 14-10-2018 IPR025438 Domain of unknown function DUF4180 C2I25_13790 c041988a003cc8b5c2ae78a7b6575a69 389 Pfam PF04235 Protein of unknown function (DUF418) 224 376 1.1E-39 T 14-10-2018 IPR007349 Domain of unknown function DUF418 C2I25_17530 395d7ce6d2062665db8bfbffac035907 166 Pfam PF07681 DoxX 16 115 2.0E-10 T 14-10-2018 IPR032808 DoxX family C2I25_20105 95df77e8e8f2cd75207bb2544efa6ca0 121 Pfam PF14037 YoqO-like protein 3 117 6.8E-38 T 14-10-2018 IPR025621 YoqO-like protein C2I25_27285 fec76aa550011c48f7b5c46a7b0a44e1 375 Gene3D G3DSA:1.20.1170.10 39 375 2.4E-129 T 14-10-2018 C2I25_27285 fec76aa550011c48f7b5c46a7b0a44e1 375 SUPERFAMILY SSF58100 33 369 4.97E-100 T 14-10-2018 C2I25_27285 fec76aa550011c48f7b5c46a7b0a44e1 375 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 46 223 4.0E-59 T 14-10-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 C2I25_15265 eccac843d3974a3aecc8d314264f4124 66 Pfam PF12606 Tumour necrosis factor receptor superfamily member 19 18 62 1.5E-16 T 14-10-2018 IPR022248 TNF receptor family, RELT C2I25_13900 c9048a486af7ee3c943713bd45cb86e1 300 Pfam PF00892 EamA-like transporter family 150 281 1.4E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I25_13900 c9048a486af7ee3c943713bd45cb86e1 300 SUPERFAMILY SSF103481 191 282 7.85E-8 T 14-10-2018 C2I25_12420 83dee4ee838d58d86b180685bda5c9d2 48 Pfam PF05968 Bacillus PapR protein 1 48 7.6E-32 T 14-10-2018 IPR009239 Bacillus PapR C2I25_00340 0fbec08af424c1116dada889b6c112ea 157 SUPERFAMILY SSF118196 1 151 3.53E-45 T 14-10-2018 IPR036413 YaeB-like superfamily C2I25_00340 0fbec08af424c1116dada889b6c112ea 157 Pfam PF01980 Uncharacterised protein family UPF0066 23 130 1.1E-30 T 14-10-2018 IPR023370 YaeB-like, N-terminal domain C2I25_00340 0fbec08af424c1116dada889b6c112ea 157 Gene3D G3DSA:2.40.30.70 2 132 3.6E-33 T 14-10-2018 IPR036414 YaeB, N-terminal domain superfamily C2I25_27155 56e7bb03ee87f51f8af750d8593456b6 339 Pfam PF01061 ABC-2 type transporter 143 302 4.1E-35 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 C2I25_09580 1652e8843d26bf5234482632a440fcae 79 Pfam PF12728 Helix-turn-helix domain 5 53 1.1E-9 T 14-10-2018 C2I25_09580 1652e8843d26bf5234482632a440fcae 79 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 53 1.6E-17 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 C2I25_17195 6d6890fcda5caeafeaca62b5b49953f9 127 Pfam PF12670 Protein of unknown function (DUF3792) 10 119 1.6E-18 T 14-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane C2I25_17195 6d6890fcda5caeafeaca62b5b49953f9 127 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 10 122 2.7E-25 T 14-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane C2I25_03765 7cf409e4e900ca54a43aa92882f1bae4 262 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 24 256 8.1E-102 T 14-10-2018 IPR014231 Sporulation protein YpjB C2I25_03765 7cf409e4e900ca54a43aa92882f1bae4 262 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 25 254 1.1E-86 T 14-10-2018 IPR014231 Sporulation protein YpjB C2I25_19505 8114e7bacd04cd1aff2c329abeef0973 152 Pfam PF14177 YkyB-like protein 16 137 4.1E-56 T 14-10-2018 IPR025552 YkyB-like protein C2I25_10795 f06c0937fa0d0ebba5476691ef55f7fa 142 Pfam PF10730 Protein of unknown function (DUF2521) 1 142 6.8E-55 T 14-10-2018 IPR019667 Uncharacterised protein family YbaK C2I25_06480 c9633413152796e8139d9be8c0d2a512 79 Pfam PF11391 Protein of unknown function (DUF2798) 15 71 5.5E-12 T 14-10-2018 IPR021529 Protein of unknown function DUF2798 C2I25_21285 bb70809ff9b96b63fd4590fb711f2442 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 118 3.0E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I25_21285 bb70809ff9b96b63fd4590fb711f2442 123 Gene3D G3DSA:3.10.180.10 9 123 2.9E-33 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_21285 bb70809ff9b96b63fd4590fb711f2442 123 SUPERFAMILY SSF54593 5 122 1.48E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I25_13110 58202b286f7edb166792838516588dde 452 Pfam PF02040 Arsenical pump membrane protein 8 446 3.4E-68 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_13110 58202b286f7edb166792838516588dde 452 PRINTS PR00758 Arsenical pump membrane protein signature 385 410 3.1E-24 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_13110 58202b286f7edb166792838516588dde 452 PRINTS PR00758 Arsenical pump membrane protein signature 344 366 3.1E-24 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_13110 58202b286f7edb166792838516588dde 452 PRINTS PR00758 Arsenical pump membrane protein signature 418 442 3.1E-24 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_13110 58202b286f7edb166792838516588dde 452 PRINTS PR00758 Arsenical pump membrane protein signature 105 129 3.1E-24 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I25_26015 dbcaa9c2d537ec175573a94d9465c9dc 220 SUPERFAMILY SSF56112 38 188 1.4E-12 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_26015 dbcaa9c2d537ec175573a94d9465c9dc 220 Gene3D G3DSA:1.10.510.10 32 182 2.1E-8 T 14-10-2018 C2I25_16785 6a89c151e8532016f19e38d404422788 408 Pfam PF12698 ABC-2 family transporter protein 20 380 2.2E-44 T 14-10-2018 C2I25_21910 3130bb92a614f07fbb4e7f4ae325ad62 303 Pfam PF04294 VanW like protein 172 299 3.7E-45 T 14-10-2018 IPR007391 Vancomycin resistance VanW C2I25_19450 5ac7a49a8fdb40d65f606e2e0d4d70e6 249 Pfam PF13152 Protein of unknown function (DUF3967) 201 232 1.7E-14 T 14-10-2018 IPR025052 Domain of unknown function DUF3967 C2I25_20925 4cdd674cdac3659253569e6ea93c7ea5 180 Pfam PF04238 Protein of unknown function (DUF420) 47 175 3.4E-43 T 14-10-2018 IPR007352 Protein of unknown function DUF420 C2I25_16810 c7f2836ee260a53da1295ffd620f91df 61 Pfam PF04024 PspC domain 3 59 4.6E-20 T 14-10-2018 IPR007168 Phage shock protein, PspC, N-terminal C2I25_14265 90834d1f61f1fc0bb39935a2befb18f7 192 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 12 164 2.6E-21 T 14-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like C2I25_13730 1128c0c0b33366e80bb586ae7d12d0d4 146 Pfam PF07849 Protein of unknown function (DUF1641) 107 128 7.0E-5 T 14-10-2018 IPR012440 Protein of unknown function DUF1641 C2I25_16410 9c8e85e0bc176a537f31e28632b188a8 469 Pfam PF07261 Replication initiation and membrane attachment 326 391 2.2E-9 T 14-10-2018 IPR006343 DnaD domain C2I25_19855 fd7d1d182e5eb120e8f433f8640e61c9 409 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 10 390 9.7E-125 T 14-10-2018 IPR014226 Sporulation integral membrane protein YlbJ C2I25_13565 df8cdeb96fd02e5119ffd902f3508e75 230 Pfam PF04172 LrgB-like family 14 226 2.1E-65 T 14-10-2018 IPR007300 CidB/LrgB family C2I25_14400 6598ca48c5b58fdf4e7f7158867a0ca9 264 Pfam PF10947 Protein of unknown function (DUF2628) 25 118 7.7E-23 T 14-10-2018 IPR024399 Protein of unknown function DUF2628 C2I25_16420 62f3aeeda548d4663055205f05a51f83 65 Pfam PF13783 Domain of unknown function (DUF4177) 2 62 1.4E-17 T 14-10-2018 IPR025234 Protein of unknown function DUF4177 C2I25_24695 0953c30d4c2816340f441ef51635375a 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 299 7.7E-50 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I25_12930 e34efe0817479d65692ff67e5e1e1215 222 Pfam PF04893 Yip1 domain 20 212 7.7E-21 T 14-10-2018 IPR006977 Yip1 domain GO:0016020 C2I25_15255 81547b459950e548945e924c02aec412 76 Pfam PF13129 Protein of unknown function (DUF3953) 32 72 1.1E-11 T 14-10-2018 IPR025018 Protein of unknown function DUF3953 C2I25_04305 c58894065ccc3e5e695f48cf7d3dc4c7 47 Pfam PF10055 Uncharacterized small protein (DUF2292) 10 46 4.7E-19 T 14-10-2018 IPR018743 Protein of unknown function DUF2292 C2I25_00705 9a4bd8a734a834ecd41a380df5ed22e6 136 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 11 134 2.1E-8 T 14-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component C2I25_26285 10b8d8c65885a4322c1eb68e5dd1ec8c 168 Pfam PF11385 Protein of unknown function (DUF3189) 3 150 2.4E-49 T 14-10-2018 IPR021525 Protein of unknown function DUF3189 C2I25_10475 1a2440a5a53794ba856ec29c8a40d3b0 46 Pfam PF14142 YrzO-like protein 1 44 3.0E-31 T 14-10-2018 IPR025417 YrzO-like protein C2I25_28380 ce2637f8f955815bdcf30f7189358b1a 39 Pfam PF13239 2TM domain 10 37 2.3E-8 T 14-10-2018 IPR025698 2TM domain C2I25_12565 708b2e55c509056f126980a8493a4244 128 Pfam PF07681 DoxX 5 93 1.9E-19 T 14-10-2018 IPR032808 DoxX family C2I25_19105 06c35db6b700373004e6b58b59bdc630 32 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 29 5.2E-9 T 14-10-2018 IPR031596 Putative methionine and alanine importer, small subunit C2I25_00120 8999c3adb717383bdcaa05727a04aac4 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 291 4.0E-10 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I25_00120 8999c3adb717383bdcaa05727a04aac4 300 SUPERFAMILY SSF161098 79 276 6.7E-8 T 14-10-2018 IPR035906 MetI-like superfamily C2I25_22420 d76090855ec87aa8d1caaac3f21f41fb 74 Pfam PF10779 Haemolysin XhlA 6 69 1.6E-10 T 14-10-2018 IPR019715 Haemolysin XhlA C2I25_24175 3f3e205b0cc116324e8eb63ff03be4ec 442 Pfam PF07670 Nucleoside recognition 136 229 5.0E-8 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I25_03460 88c2b6311a9854332a9ac8df41e6e913 247 Pfam PF02706 Chain length determinant protein 4 92 3.5E-10 T 14-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 C2I25_05855 624258503c0fcb648c32debae345e3ce 292 Pfam PF02517 CAAX protease self-immunity 185 281 4.1E-16 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_16255 5a0d653f527e8bdba13c0297c5386c89 101 Pfam PF14007 YtpI-like protein 5 90 4.7E-35 T 14-10-2018 IPR025618 YtpI-like protein C2I25_15165 dae9ff4c3fe7232a7ec8cd18a608aa86 221 Pfam PF04012 PspA/IM30 family 2 218 3.9E-48 T 14-10-2018 IPR007157 PspA/IM30 C2I25_05445 da3d4d0e5d77446e1c9ff85dab8f759a 224 Pfam PF03741 Integral membrane protein TerC family 11 181 8.8E-44 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I25_05445 da3d4d0e5d77446e1c9ff85dab8f759a 224 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 182 9.3E-70 T 14-10-2018 IPR022301 Integral membrane protein YjbE C2I25_00300 3f6ddbf21549b21238c3aadd5b679516 195 Pfam PF14005 YpjP-like protein 62 193 5.2E-61 T 14-10-2018 IPR025616 YpjP-like protein C2I25_03975 3f52c647afdaa3ab42282c9f77054090 187 Pfam PF02517 CAAX protease self-immunity 96 179 5.0E-11 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I25_19765 977983df24ac6771bb934ceca7f2f790 311 Pfam PF02628 Cytochrome oxidase assembly protein 7 286 5.3E-39 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 C2I25_19765 977983df24ac6771bb934ceca7f2f790 311 Hamap MF_01664 Heme A synthase [ctaA]. 1 301 30.891 T 14-10-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 C2I25_24905 40f908848bbecb33029caaceac26f0c9 43 SUPERFAMILY SSF109854 5 34 6.41E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I25_15315 11bb2dbb84259aca4b381e69e63e9617 98 Pfam PF13143 Protein of unknown function (DUF3986) 3 89 1.7E-32 T 14-10-2018 IPR025047 Protein of unknown function DUF3986 C2I25_28425 6d2bf1dc8ff65fca7c771ab07c40552e 51 Pfam PF13067 Protein of unknown function (DUF3930) 1 51 5.7E-36 T 14-10-2018 IPR025172 Protein of unknown function DUF3930 C2I25_15750 524669251e1a8c8f530bc1b737dabbcb 265 Pfam PF01636 Phosphotransferase enzyme family 45 230 2.7E-20 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I25_15750 524669251e1a8c8f530bc1b737dabbcb 265 SUPERFAMILY SSF56112 3 231 1.22E-30 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily C2I25_15750 524669251e1a8c8f530bc1b737dabbcb 265 Gene3D G3DSA:3.90.1200.10 80 264 4.0E-24 T 14-10-2018 C2I25_09315 e8b520161edcecd10a01b165c1b86bd5 341 PRINTS PR01228 Eggshell protein signature 8 24 2.0E-6 T 14-10-2018 C2I25_09315 e8b520161edcecd10a01b165c1b86bd5 341 PRINTS PR01228 Eggshell protein signature 147 157 2.0E-6 T 14-10-2018 C2I25_09315 e8b520161edcecd10a01b165c1b86bd5 341 PRINTS PR01228 Eggshell protein signature 120 135 2.0E-6 T 14-10-2018 C2I25_09315 e8b520161edcecd10a01b165c1b86bd5 341 PRINTS PR01228 Eggshell protein signature 183 201 2.0E-6 T 14-10-2018 C2I25_02735 8165785a20d056026bdf63f2bcdf68ed 135 Pfam PF13078 Protein of unknown function (DUF3942) 8 132 5.9E-63 T 14-10-2018 IPR025074 Protein of unknown function DUF3942 C2I25_02900 74c0e625bf4ce6eb100bbc7e89315ea8 140 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 131 6.2E-63 T 14-10-2018 IPR019723 Uncharacterised protein, YfmQ C2I25_25125 b0557546223f243a2576d15096f6b292 62 Pfam PF13113 Protein of unknown function (DUF3970) 1 56 1.8E-21 T 14-10-2018 IPR025088 Protein of unknown function DUF3970 C2I25_15660 2e2919d609c3967650fea315324cd365 137 Pfam PF13027 Protein of unknown function (DUF3888) 33 113 3.3E-14 T 14-10-2018 IPR024984 Protein of unknown function DUF3888 C2I25_03325 00ff6d79139283333e70f9ac615504eb 100 Pfam PF13143 Protein of unknown function (DUF3986) 11 97 7.6E-26 T 14-10-2018 IPR025047 Protein of unknown function DUF3986 C2I25_25725 5a07ed72ff06123b68b3cc5d7af96f0d 269 Pfam PF13315 Protein of unknown function (DUF4085) 65 260 1.2E-81 T 14-10-2018 IPR025144 Protein of unknown function DUF4085 C2I25_14080 750532f4afc043fadbb5f8412f636e53 61 Gene3D G3DSA:1.20.1260.10 8 60 3.8E-5 T 14-10-2018 IPR012347 Ferritin-like C2I25_22585 9c1fdb1bb7464f674ecfbdcf384d8ebb 445 Pfam PF12791 Anti-sigma factor N-terminus 8 51 7.7E-15 T 14-10-2018 IPR024449 Anti-sigma factor RsgI, N-terminal C2I25_05685 cf4d7c75fb2d3c2f7403d56a0ff5da53 204 Pfam PF10737 Spore germination protein GerPC 23 198 1.2E-60 T 14-10-2018 IPR019673 Spore germination protein GerPC C2I25_19330 15c1381faded876b42824f55e9fac4f4 255 SUPERFAMILY SSF158560 1 86 3.66E-18 T 14-10-2018 C2I25_03105 a2e5da2494a38b2b870eadb32f047081 190 Pfam PF03963 Flagellar hook capping protein - N-terminal region 32 99 4.6E-17 T 14-10-2018 IPR005648 Flagellar hook capping protein C2I25_17330 fb6604418cbbdc1f9ebb2c27fdb6a55c 114 Pfam PF14470 Bacterial PH domain 12 110 5.1E-12 T 14-10-2018 IPR039519 YokE-like, PH domain C2I25_06460 4ca8245946df3de3aea91e9e83a2170b 129 Pfam PF11181 Heat induced stress protein YflT 12 109 8.1E-31 T 14-10-2018 IPR025889 General stress protein 17M-like domain C2I25_14130 e2406bc3128382b0dfad08eba9f1c3e8 130 Pfam PF12281 Nucleotidyltransferase 20 121 1.8E-4 T 14-10-2018 IPR022550 Nucleotidyltransferase 8 C2I25_23155 3507b9f25332bf86d2e113530a44a3f2 119 Pfam PF12676 Protein of unknown function (DUF3796) 4 114 7.0E-33 T 14-10-2018 IPR024257 Protein of unknown function DUF3796 C2I25_03340 65d0a80dae569a5ffda16bc4653fd231 113 Pfam PF04341 Protein of unknown function, DUF485 22 105 5.0E-23 T 14-10-2018 IPR007436 Protein of unknown function DUF485 C2I25_01700 fca8a7ceca03994c2acae3448da48334 91 SUPERFAMILY SSF47336 1 81 3.45E-11 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_01700 fca8a7ceca03994c2acae3448da48334 91 Gene3D G3DSA:1.10.1200.10 5 85 7.6E-13 T 14-10-2018 IPR036736 ACP-like superfamily C2I25_26185 2dc71905f94e0dd73c2d28b368157255 115 Gene3D G3DSA:3.30.70.120 2 108 1.2E-29 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I25_26185 2dc71905f94e0dd73c2d28b368157255 115 SUPERFAMILY SSF102705 6 108 9.42E-17 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily C2I25_26185 2dc71905f94e0dd73c2d28b368157255 115 Pfam PF03091 CutA1 divalent ion tolerance protein 62 105 3.0E-7 T 14-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 C2I25_18670 769cafdaf722b04da6d7dc5a7d0ce613 79 Pfam PF13033 Protein of unknown function (DUF3894) 24 77 3.5E-37 T 14-10-2018 IPR024993 Protein of unknown function DUF3894 C2I25_07205 7980bdb333971dfdb35ae7e2d7c26954 134 Pfam PF07681 DoxX 7 85 9.6E-20 T 14-10-2018 IPR032808 DoxX family C2I25_07010 b971487051b650b59302351fe26a079d 186 Pfam PF08006 Protein of unknown function (DUF1700) 1 184 1.2E-65 T 14-10-2018 IPR012963 Protein of unknown function DUF1700 C2I25_08035 85124df890fbf3cde17dca4bad11699f 573 Pfam PF10101 Predicted membrane protein (DUF2339) 96 409 1.7E-29 T 14-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane C2I25_08035 85124df890fbf3cde17dca4bad11699f 573 Pfam PF10101 Predicted membrane protein (DUF2339) 389 564 1.7E-10 T 14-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane C2I25_28315 1628adefd296b3508b86641464456cc7 71 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 8.5E-24 T 14-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I25_02685 9f909b55b680d4afd4fb487a60e4448b 415 Pfam PF04286 Protein of unknown function (DUF445) 40 415 7.7E-86 T 14-10-2018 IPR007383 Protein of unknown function DUF445 C2I25_06605 424bdd7ba2dd9f9f847f81502c074fb5 184 Pfam PF04982 HPP family 64 180 5.0E-43 T 14-10-2018 IPR007065 HPP C2I25_24990 5f068dc44ab6972c217f8aadc0a2cd64 361 Pfam PF01594 AI-2E family transporter 18 348 2.5E-84 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like C2I25_03775 4bca198c784a3641d9def1b7cf4a0b2b 190 Pfam PF07187 Protein of unknown function (DUF1405) 18 174 1.9E-57 T 14-10-2018 IPR009845 Protein of unknown function DUF1405 C2I25_19350 d178b4cbbeca8029063752f94e91075c 97 Pfam PF13065 Protein of unknown function (DUF3928) 1 95 1.3E-63 T 14-10-2018 IPR025170 Protein of unknown function DUF3928 C2I25_23795 6fc19a9c8751c4d3f42d3ab627869d07 439 Pfam PF03222 Tryptophan/tyrosine permease family 40 431 1.7E-17 T 14-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 C2I25_21715 078bc6ebfb26fa64dd7a494b0f5e3883 160 Pfam PF07849 Protein of unknown function (DUF1641) 118 155 5.1E-18 T 14-10-2018 IPR012440 Protein of unknown function DUF1641 C2I25_15850 dd9c461d1a97d79a41a7665cb90f1268 134 Pfam PF06713 Bacterial PH domain 62 123 3.6E-8 T 14-10-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 C2I25_03895 c9604e345e3e4d016035fcc1ed748b36 203 PIRSF PIRSF036710 1 203 2.9E-97 T 14-10-2018 IPR014617 Predicted membrane protein, Bacillus YphA type C2I25_05795 6e210f6b8055132fd0b3cd5f7fb9f6dd 99 Pfam PF09874 Predicted membrane protein (DUF2101) 9 77 7.4E-5 T 14-10-2018 IPR018663 Protein of unknown function DUF2101, membrane C2I25_10495 5176aa0ea2af4c905a925efbb952639a 33 Pfam PF13134 Protein of unknown function (DUF3948) 1 32 5.2E-19 T 14-10-2018 IPR025034 Protein of unknown function DUF3948 C2I25_24145 814cef547914c56c28cf0742049d88b1 395 Pfam PF12051 Protein of unknown function (DUF3533) 14 367 2.9E-25 T 14-10-2018 IPR022703 Domain of unknown function DUF3533 C2I25_04280 411e774e8c24c4614c5451dabe76d8e4 66 Pfam PF13046 Protein of unknown function (DUF3906) 1 64 1.4E-31 T 14-10-2018 IPR024998 Protein of unknown function DUF3906 C2I25_15095 ed02b268ee5e5cf846c9aad194e6d0ba 169 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 18 153 7.3E-47 T 14-10-2018 IPR018697 Protein of unknown function DUF2199 C2I25_09655 b6e48ad029bbc0f64722d283fe0a26db 473 Pfam PF03553 Na+/H+ antiporter family 158 450 2.3E-62 T 14-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I25_09655 b6e48ad029bbc0f64722d283fe0a26db 473 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 9 455 1.2E-144 T 14-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 C2I25_04140 eb8fd4c179b26344424773fa2ae51ce6 332 Pfam PF01384 Phosphate transporter family 22 320 2.7E-90 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 C2I25_04825 07f87bd18027171dda08c0af2ab3f000 449 Pfam PF02386 Cation transport protein 42 429 1.1E-59 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 C2I25_12330 a0c3aa98b12bf2c59b7b72ab93a06f99 345 Pfam PF13303 Phosphotransferase system, EIIC 28 331 4.4E-59 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I25_01560 f8fb82f87510db58c975bad05fdb7ad7 121 Pfam PF13141 Protein of unknown function (DUF3979) 8 119 7.0E-76 T 14-10-2018 IPR025045 Protein of unknown function DUF3979 C2I25_27200 e2a8e6322dcd70e53a01f57ea52914b8 275 Gene3D G3DSA:2.30.30.40 178 250 4.5E-6 T 14-10-2018 C2I25_00840 538b74fd6103dada7eac6fdfa3f36d9f 63 Pfam PF13128 Protein of unknown function (DUF3954) 14 55 8.1E-15 T 14-10-2018 IPR025017 Protein of unknown function DUF3954 C2I25_18305 6a08dc748ae561caac675477e5dbb937 133 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 4 133 2.0E-13 T 14-10-2018 C2I25_19725 f709edd488f8f108f35fd21b921f2fce 66 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 5.4E-31 T 14-10-2018 IPR019241 Protein of unknown function DUF2197 C2I25_21160 f6da790707136665cf4a78d97c02b827 314 Pfam PF12679 ABC-2 family transporter protein 3 313 1.6E-16 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I25_15605 e29b10b124f6e38f6292b3d93961900f 74 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 8.2E-17 T 14-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I25_20750 b6d0a6e5eca15df6650452c339ecfdcf 141 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 132 5.6E-62 T 14-10-2018 IPR019723 Uncharacterised protein, YfmQ C2I25_23780 63a648ea52a7674856b77fe9f81b91a4 252 Pfam PF06161 Protein of unknown function (DUF975) 152 242 2.1E-22 T 14-10-2018 IPR010380 Protein of unknown function DUF975 C2I25_04485 e3200c4a35be6e09f0c285652c9a6806 143 Pfam PF14184 Regulatory protein YrvL 15 140 6.2E-39 T 14-10-2018 IPR025912 Regulatory protein YrvL