locus-tag	class	description
BC8716_00010	COG5002	protein histidine kinase activity
BC8716_00015	COG5002	protein histidine kinase activity
BC8716_00050	COG1396	sequence-specific DNA binding
BC8716_00065	COG0395	ABC-type sugar transport system, permease component
BC8716_00070	COG1175	transmembrane transport
BC8716_00120	COG1522	sequence-specific DNA binding
BC8716_00125	COG1279	arginine transmembrane transporter activity
BC8716_00130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC8716_00135	COG2318	DinB family
BC8716_00140	COG3011	Protein conserved in bacteria
BC8716_00220	COG5577	PFAM Coat F domain
BC8716_00230	COG2423	ornithine cyclodeaminase activity
BC8716_00235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC8716_00250	COG0010	Belongs to the arginase family
BC8716_00265	COG1686	Belongs to the peptidase S11 family
BC8716_00270	COG0640	Transcriptional regulator
BC8716_00275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC8716_00285	COG2814	Major facilitator Superfamily
BC8716_00295	COG1131	(ABC) transporter
BC8716_00300	COG2205	protein histidine kinase activity
BC8716_00305	COG0745	RESPONSE REGULATOR receiver
BC8716_00310	COG3344	reverse transcriptase
BC8716_00320	COG3764	Sortase (surface protein transpeptidase)
BC8716_00330	COG3397	chitin binding
BC8716_00335	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_00345	COG3732	PTS system glucitol sorbitol-specific
BC8716_00365	COG0246	Mannitol dehydrogenase
BC8716_00370	COG2721	sulfolactate sulfo-lyase activity
BC8716_00375	COG0673	inositol 2-dehydrogenase activity
BC8716_00380	COG5578	integral membrane protein
BC8716_00390	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BC8716_00405	COG0395	ABC-type sugar transport system, permease component
BC8716_00410	COG4209	transmembrane transport
BC8716_00415	COG1653	transport
BC8716_00420	COG2207	Transcriptional regulator
BC8716_00430	COG3250	beta-galactosidase activity
BC8716_00430	COG5297	Belongs to the glycosyl hydrolase family 6
BC8716_00440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC8716_00455	COG0395	ABC-type sugar transport system, permease component
BC8716_00460	COG4209	transmembrane transport
BC8716_00465	COG2207	Transcriptional regulator
BC8716_00465	COG4753	response regulator
BC8716_00470	COG2972	Histidine kinase
BC8716_00475	COG1501	Belongs to the glycosyl hydrolase 31 family
BC8716_00480	COG3344	reverse transcriptase
BC8716_00490	COG1846	Transcriptional regulator
BC8716_00490	COG1940	carbohydrate kinase activity
BC8716_00495	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BC8716_00505	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC8716_00510	COG3340	Belongs to the peptidase S51 family
BC8716_00520	COG0717	Belongs to the dCTP deaminase family
BC8716_00525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BC8716_00535	COG0523	cobalamin synthesis protein
BC8716_00540	COG3443	Belongs to the bacterial solute-binding protein 9 family
BC8716_00545	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC8716_00545	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC8716_00550	COG1121	(ABC) transporter
BC8716_00555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC8716_00560	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_00565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC8716_00575	COG1414	Transcriptional regulator
BC8716_00580	COG0129	dihydroxy-acid dehydratase activity
BC8716_00605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BC8716_00610	COG0716	FMN binding
BC8716_00615	COG1597	lipid kinase activity
BC8716_00620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BC8716_00625	COG0154	amidase activity
BC8716_00630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BC8716_00635	COG2318	DinB family
BC8716_00670	COG4851	CamS sex pheromone cAM373 precursor
BC8716_00675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BC8716_00680	COG0210	DNA helicase
BC8716_00685	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BC8716_00690	COG1120	ATPase activity
BC8716_00695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC8716_00700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC8716_00720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BC8716_00725	COG4496	protein, YerC YecD
BC8716_00730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BC8716_00735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BC8716_00755	COG1510	regulation of RNA biosynthetic process
BC8716_00825	COG1131	(ABC) transporter
BC8716_00830	COG2197	response regulator
BC8716_00835	COG4585	Histidine kinase
BC8716_00855	COG0151	Belongs to the GarS family
BC8716_00860	COG0138	bifunctional purine biosynthesis protein purh
BC8716_00865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BC8716_00870	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BC8716_00875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BC8716_00880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC8716_00885	COG0047	phosphoribosylformylglycinamidine synthase activity
BC8716_00890	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC8716_00895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BC8716_00900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BC8716_00905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BC8716_00910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BC8716_00950	COG3654	unkown
BC8716_00975	COG4565	transcriptional regulatory protein
BC8716_00980	COG3290	protein histidine kinase activity
BC8716_00985	COG0025	NhaP-type Na H and K H
BC8716_01000	COG1191	sigma factor activity
BC8716_01010	COG3328	transposase activity
BC8716_01035	COG1132	(ABC) transporter
BC8716_01040	COG1132	(ABC) transporter
BC8716_01055	COG1755	Isoprenylcysteine carboxyl methyltransferase
BC8716_01060	COG3424	synthase
BC8716_01065	COG0789	Transcriptional regulator
BC8716_01070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC8716_01075	COG1904	glucuronate isomerase
BC8716_01080	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BC8716_01085	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_01090	COG1349	DNA-binding transcription factor activity
BC8716_01095	COG2059	Chromate
BC8716_01100	COG2059	Chromate
BC8716_01105	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BC8716_01110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC8716_01125	COG3764	Sortase (surface protein transpeptidase)
BC8716_01145	COG1510	regulation of RNA biosynthetic process
BC8716_01155	COG1454	alcohol dehydrogenase
BC8716_01160	COG2186	Transcriptional regulator
BC8716_01165	COG1556	Lactate utilization protein
BC8716_01170	COG1139	Iron-sulfur cluster binding protein
BC8716_01175	COG0247	lactate metabolic process
BC8716_01180	COG1620	l-lactate permease
BC8716_01190	COG2124	cytochrome p450
BC8716_01195	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BC8716_01200	COG0326	Molecular chaperone. Has ATPase activity
BC8716_01205	COG1335	isochorismatase
BC8716_01215	COG1476	TRANSCRIPTIONal
BC8716_01220	COG0737	Belongs to the 5'-nucleotidase family
BC8716_01225	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_01230	COG3290	protein histidine kinase activity
BC8716_01230	COG3829	transcription factor binding
BC8716_01240	COG1408	metallophosphoesterase
BC8716_01260	COG2252	PERMEase
BC8716_01285	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BC8716_01295	COG2376	Dihydroxyacetone kinase
BC8716_01305	COG1846	Transcriptional regulator
BC8716_01315	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC8716_01325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BC8716_01330	COG0577	efflux transmembrane transporter activity
BC8716_01335	COG1136	(ABC) transporter
BC8716_01355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BC8716_01365	COG1595	DNA-templated transcription, initiation
BC8716_01405	COG0791	NLP P60 protein
BC8716_01405	COG0741	lytic transglycosylase activity
BC8716_01415	COG3226	Transcriptional regulator
BC8716_01420	COG0596	Alpha beta hydrolase
BC8716_01435	COG3226	Transcriptional regulator
BC8716_01485	COG3226	Transcriptional regulator
BC8716_01510	COG0577	efflux transmembrane transporter activity
BC8716_01515	COG1136	(ABC) transporter
BC8716_01525	COG5002	protein histidine kinase activity
BC8716_01545	COG0519	Catalyzes the synthesis of GMP from XMP
BC8716_01545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BC8716_01550	COG1305	Transglutaminase-like
BC8716_01555	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BC8716_01560	COG0714	Associated with various cellular activities
BC8716_01570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BC8716_01590	COG0768	penicillin binding
BC8716_01595	COG1943	Transposase
BC8716_01600	COG0778	Nitroreductase
BC8716_01610	COG4824	toxin secretion phage lysis holin
BC8716_01650	COG0281	malic enzyme
BC8716_01655	COG3493	citrate carrier protein
BC8716_01660	COG4565	transcriptional regulatory protein
BC8716_01665	COG3290	protein histidine kinase activity
BC8716_01670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BC8716_01675	COG1126	abc transporter atp-binding protein
BC8716_01680	COG0765	amino acid transport
BC8716_01685	COG0765	amino acid transport
BC8716_01705	COG0463	Glycosyl transferase, family 2
BC8716_01715	COG4485	Bacterial membrane protein, YfhO
BC8716_01730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BC8716_01735	COG2427	Protein of unknown function (DUF1641)
BC8716_01740	COG3383	formate dehydrogenase (NAD+) activity
BC8716_01745	COG2116	formate transmembrane transporter activity
BC8716_01750	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BC8716_01755	COG0314	molybdopterin synthase activity
BC8716_01760	COG1763	Mo-molybdopterin cofactor biosynthetic process
BC8716_01765	COG0303	'Molybdopterin
BC8716_01770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC8716_01780	COG0746	molybdenum cofactor guanylyltransferase activity
BC8716_01785	COG0315	cyclic pyranopterin monophosphate synthase activity
BC8716_01790	COG2368	4-hydroxyphenylacetate
BC8716_01795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BC8716_01800	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BC8716_01805	COG4821	SIS domain
BC8716_01830	COG0459	protein refolding
BC8716_01835	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BC8716_01840	COG1266	CAAX protease self-immunity
BC8716_01850	COG0371	Dehydrogenase
BC8716_01855	COG1464	Belongs to the NlpA lipoprotein family
BC8716_01860	COG2011	ABC-type metal ion transport system permease component
BC8716_01865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC8716_01870	COG0805	protein transport
BC8716_01875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC8716_01880	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BC8716_01885	COG0488	(ABC) transporter
BC8716_01890	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BC8716_01895	COG0456	acetyltransferase
BC8716_01900	COG1214	PFAM Peptidase M22, glycoprotease
BC8716_01905	COG0802	atpase or kinase
BC8716_01910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BC8716_01920	COG0626	cystathionine gamma-synthase activity
BC8716_01925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BC8716_01930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BC8716_01935	COG1285	pathogenesis
BC8716_02025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_02025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_02025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_02035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_02035	COG3711	transcriptional antiterminator
BC8716_02045	COG0384	phenazine biosynthesis protein PhzF
BC8716_02075	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BC8716_02080	COG1687	branched-chain amino acid
BC8716_02085	COG5646	InterPro IPR014922
BC8716_02115	COG0473	3-isopropylmalate dehydrogenase activity
BC8716_02120	COG1802	Transcriptional regulator
BC8716_02125	COG2514	catechol 2,3-dioxygenase activity
BC8716_02130	COG2140	Oxalate decarboxylase
BC8716_02140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC8716_02145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC8716_02150	COG0640	Transcriptional regulator
BC8716_02155	COG0346	lactoylglutathione lyase activity
BC8716_02160	COG0640	Transcriptional regulator
BC8716_02165	COG1329	Transcriptional regulator
BC8716_02170	COG1278	Cold shock
BC8716_02210	COG0662	Cupin 2, conserved barrel domain protein
BC8716_02215	COG2226	methyltransferase
BC8716_02220	COG4282	regulation of fungal-type cell wall biogenesis
BC8716_02260	COG3091	SprT-like family
BC8716_02265	COG2183	response to ionizing radiation
BC8716_02275	COG1191	sigma factor activity
BC8716_02280	COG2172	sigma factor antagonist activity
BC8716_02285	COG1366	Belongs to the anti-sigma-factor antagonist family
BC8716_02290	COG2208	phosphoserine phosphatase activity
BC8716_02295	COG2172	sigma factor antagonist activity
BC8716_02300	COG1366	Belongs to the anti-sigma-factor antagonist family
BC8716_02305	COG1366	Belongs to the anti-sigma-factor antagonist family
BC8716_02310	COG2337	Toxic component of a toxin-antitoxin (TA) module
BC8716_02315	COG0864	Transcriptional regulator
BC8716_02320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC8716_02325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BC8716_02330	COG0736	holo-[acyl-carrier-protein] synthase activity
BC8716_02335	COG0705	Rhomboid family
BC8716_02345	COG1368	sulfuric ester hydrolase activity
BC8716_02350	COG1876	peptidase activity
BC8716_02360	COG5578	integral membrane protein
BC8716_02365	COG3214	Protein conserved in bacteria
BC8716_02375	COG0673	inositol 2-dehydrogenase activity
BC8716_02380	COG1082	Xylose isomerase domain protein TIM barrel
BC8716_02390	COG1320	monovalent cation:proton antiporter activity
BC8716_02395	COG2212	antiporter activity
BC8716_02400	COG1863	multisubunit Na H antiporter MnhE subunit
BC8716_02405	COG0651	ATP synthesis coupled electron transport
BC8716_02410	COG1006	Multisubunit Na H antiporter MnhC subunit
BC8716_02415	COG2111	Na H antiporter
BC8716_02420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC8716_02420	COG2111	Na H antiporter
BC8716_02425	COG2205	protein histidine kinase activity
BC8716_02435	COG1733	regulation of RNA biosynthetic process
BC8716_02440	COG4608	Belongs to the ABC transporter superfamily
BC8716_02445	COG0791	NLP P60 protein
BC8716_02450	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC8716_02455	COG4166	transmembrane transport
BC8716_02460	COG0444	Belongs to the ABC transporter superfamily
BC8716_02465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC8716_02470	COG0601	transmembrane transport
BC8716_02475	COG2362	D-Aminopeptidase
BC8716_02480	COG4191	Histidine kinase
BC8716_02485	COG0784	Response regulator, receiver
BC8716_02490	COG0765	amino acid transport
BC8716_02495	COG0765	amino acid transport
BC8716_02500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC8716_02510	COG2962	Rard protein
BC8716_02515	COG2706	6-phosphogluconolactonase activity
BC8716_02520	COG0686	Belongs to the AlaDH PNT family
BC8716_02525	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BC8716_02525	COG2508	Transcriptional regulator
BC8716_02535	COG0531	amino acid
BC8716_02540	COG1876	peptidase activity
BC8716_02555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC8716_02560	COG0596	Alpha beta hydrolase
BC8716_02565	COG0861	Integral membrane protein TerC family
BC8716_02575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC8716_02580	COG2818	Glycosylase
BC8716_02595	COG1404	Belongs to the peptidase S8 family
BC8716_02600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC8716_02610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BC8716_02625	COG3835	regulator
BC8716_02630	COG1929	Belongs to the glycerate kinase type-1 family
BC8716_02645	COG0024	Methionine aminopeptidase
BC8716_02650	COG0456	acetyltransferase
BC8716_02655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC8716_02670	COG1846	Transcriptional regulator
BC8716_02675	COG2239	Acts as a magnesium transporter
BC8716_02680	COG2197	response regulator
BC8716_02685	COG4585	Histidine kinase
BC8716_02690	COG3239	Fatty acid desaturase
BC8716_02695	COG2207	Transcriptional regulator
BC8716_02700	COG1486	melibiose metabolic process
BC8716_02705	COG0586	Pfam SNARE associated Golgi protein
BC8716_02710	COG1191	sigma factor activity
BC8716_02720	COG0395	ABC-type sugar transport system, permease component
BC8716_02725	COG4209	transmembrane transport
BC8716_02730	COG2207	Transcriptional regulator
BC8716_02730	COG4753	response regulator
BC8716_02735	COG2972	Histidine kinase
BC8716_02750	COG2223	nitrite transmembrane transporter activity
BC8716_02760	COG2197	response regulator
BC8716_02775	COG2181	nitrate reductase activity
BC8716_02785	COG1140	nitrate reductase beta subunit
BC8716_02790	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BC8716_02800	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC8716_02805	COG1263	PTS System
BC8716_02805	COG2190	(PTS) system
BC8716_02805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_02810	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BC8716_02815	COG1737	Transcriptional regulator
BC8716_02890	COG1511	domain protein
BC8716_02895	COG1674	ftsk spoiiie
BC8716_02900	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC8716_02910	COG4842	Belongs to the WXG100 family
BC8716_02915	COG0395	ABC-type sugar transport system, permease component
BC8716_02920	COG1175	transmembrane transport
BC8716_02935	COG1119	ATPase activity
BC8716_02940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC8716_02960	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BC8716_02965	COG3457	Alanine racemase
BC8716_02970	COG0626	cystathionine gamma-synthase activity
BC8716_02975	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BC8716_03005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC8716_03010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC8716_03015	COG0159	tryptophan synthase activity
BC8716_03045	COG2610	gluconate transmembrane transporter activity
BC8716_03050	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BC8716_03055	COG3395	kinase activity
BC8716_03060	COG1349	DNA-binding transcription factor activity
BC8716_03065	COG0697	spore germination
BC8716_03095	COG3844	kynureninase activity
BC8716_03100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BC8716_03105	COG2271	Major facilitator Superfamily
BC8716_03110	COG5294	Protein conserved in bacteria
BC8716_03130	COG3394	polysaccharide catabolic process
BC8716_03135	COG1486	melibiose metabolic process
BC8716_03140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC8716_03145	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC8716_03150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC8716_03155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BC8716_03165	COG0798	PFAM Bile acid sodium symporter
BC8716_03180	COG0163	prenyltransferase activity
BC8716_03185	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_03190	COG1312	Catalyzes the dehydration of D-mannonate
BC8716_03195	COG1063	alcohol dehydrogenase
BC8716_03200	COG1053	succinate dehydrogenase
BC8716_03205	COG0473	3-isopropylmalate dehydrogenase activity
BC8716_03210	COG0583	DNA-binding transcription factor activity
BC8716_03235	COG2188	Transcriptional regulator
BC8716_03240	COG1131	(ABC) transporter
BC8716_03250	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC8716_03255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BC8716_03270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BC8716_03270	COG1587	Uroporphyrinogen-III synthase
BC8716_03275	COG0529	Catalyzes the synthesis of activated sulfate
BC8716_03280	COG0306	phosphate transporter
BC8716_03285	COG2046	Belongs to the sulfate adenylyltransferase family
BC8716_03290	COG0175	sulfate reduction
BC8716_03305	COG1116	anion transmembrane transporter activity
BC8716_03310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC8716_03315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_03320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC8716_03325	COG0431	NADPH-dependent FMN reductase
BC8716_03330	COG5583	Uncharacterized small protein (DUF2292)
BC8716_03340	COG2258	MOSC domain
BC8716_03365	COG0318	PFAM AMP-dependent synthetase and ligase
BC8716_03380	COG1942	4-Oxalocrotonate Tautomerase
BC8716_03385	COG0477	Major facilitator Superfamily
BC8716_03395	COG4126	flavin adenine dinucleotide binding
BC8716_03420	COG2508	Transcriptional regulator
BC8716_03425	COG0673	inositol 2-dehydrogenase activity
BC8716_03435	COG1940	carbohydrate kinase activity
BC8716_03445	COG1070	Carbohydrate kinase
BC8716_03450	COG2115	Belongs to the xylose isomerase family
BC8716_03455	COG1414	Transcriptional regulator
BC8716_03460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC8716_03470	COG4608	Belongs to the ABC transporter superfamily
BC8716_03475	COG0444	Belongs to the ABC transporter superfamily
BC8716_03490	COG0747	negative chemotaxis
BC8716_03495	COG1228	amidohydrolase
BC8716_03500	COG1228	amidohydrolase
BC8716_03525	COG1653	transport
BC8716_03530	COG0395	ABC-type sugar transport system, permease component
BC8716_03535	COG4209	transmembrane transport
BC8716_03545	COG3507	Belongs to the glycosyl hydrolase 43 family
BC8716_03550	COG2207	Transcriptional regulator
BC8716_03550	COG0662	Cupin 2, conserved barrel domain protein
BC8716_03555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC8716_03560	COG2011	ABC-type metal ion transport system permease component
BC8716_03565	COG1464	Belongs to the NlpA lipoprotein family
BC8716_03570	COG1473	amidohydrolase
BC8716_03580	COG2084	Dehydrogenase
BC8716_03590	COG1737	Transcriptional regulator
BC8716_03595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC8716_03600	COG2186	Transcriptional regulator
BC8716_03605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BC8716_03615	COG4145	pantothenate transmembrane transporter activity
BC8716_03655	COG0710	3-dehydroquinate dehydratase activity
BC8716_03665	COG0655	NAD(P)H dehydrogenase (quinone) activity
BC8716_03675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC8716_03690	COG0745	RESPONSE REGULATOR receiver
BC8716_03695	COG2205	protein histidine kinase activity
BC8716_03715	COG2610	gluconate transmembrane transporter activity
BC8716_03720	COG4948	Mandelate Racemase Muconate Lactonizing
BC8716_03725	COG0800	Aldolase
BC8716_03730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC8716_03740	COG2755	lipolytic protein G-D-S-L family
BC8716_03745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC8716_03760	COG1215	transferase activity, transferring glycosyl groups
BC8716_03775	COG0438	transferase activity, transferring glycosyl groups
BC8716_03790	COG0438	transferase activity, transferring glycosyl groups
BC8716_03820	COG2226	methyltransferase
BC8716_03830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC8716_03835	COG0535	radical SAM domain protein
BC8716_03840	COG0471	metal ion transport
BC8716_03845	COG1929	Belongs to the glycerate kinase type-1 family
BC8716_03850	COG3212	peptidase
BC8716_03855	COG3212	peptidase
BC8716_03860	COG3850	Histidine kinase
BC8716_03860	COG5002	protein histidine kinase activity
BC8716_03865	COG0745	RESPONSE REGULATOR receiver
BC8716_03870	COG4821	SIS domain
BC8716_03875	COG2188	Transcriptional regulator
BC8716_03885	COG3584	3D domain protein
BC8716_03885	COG1388	LysM domain
BC8716_03890	COG3344	reverse transcriptase
BC8716_03895	COG1940	carbohydrate kinase activity
BC8716_03905	COG0395	ABC-type sugar transport system, permease component
BC8716_03910	COG4209	transmembrane transport
BC8716_03915	COG2207	Transcriptional regulator
BC8716_03915	COG4753	response regulator
BC8716_03920	COG2972	Histidine kinase
BC8716_03925	COG5578	integral membrane protein
BC8716_03935	COG0383	alpha-mannosidase activity
BC8716_03950	COG2723	6-phospho-beta-galactosidase activity
BC8716_03965	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_03970	COG1309	transcriptional regulator
BC8716_03975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_03975	COG3711	transcriptional antiterminator
BC8716_03980	COG2723	6-phospho-beta-galactosidase activity
BC8716_03985	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC8716_03990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC8716_03995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC8716_04000	COG1357	PFAM Pentapeptide repeats (8 copies)
BC8716_04020	COG2807	transmembrane transport
BC8716_04030	COG2186	Transcriptional regulator
BC8716_04035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC8716_04040	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_04060	COG1312	Catalyzes the dehydration of D-mannonate
BC8716_04105	COG0840	transmembrane signaling receptor activity
BC8716_04110	COG2851	Citrate transporter
BC8716_04125	COG3290	protein histidine kinase activity
BC8716_04125	COG3829	transcription factor binding
BC8716_04130	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BC8716_04135	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BC8716_04140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC8716_04150	COG1917	Cupin 2, conserved barrel domain protein
BC8716_04155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_04155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_04160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_04165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_04165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_04165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_04170	COG0191	fructose-bisphosphate aldolase activity
BC8716_04175	COG3711	transcriptional antiterminator
BC8716_04180	COG0246	Mannitol dehydrogenase
BC8716_04185	COG2721	sulfolactate sulfo-lyase activity
BC8716_04190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BC8716_04200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC8716_04205	COG1063	alcohol dehydrogenase
BC8716_04215	COG1653	transport
BC8716_04220	COG1175	transmembrane transport
BC8716_04240	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC8716_04245	COG0673	inositol 2-dehydrogenase activity
BC8716_04250	COG0191	fructose-bisphosphate aldolase activity
BC8716_04255	COG1082	Xylose isomerase domain protein TIM barrel
BC8716_04260	COG0673	inositol 2-dehydrogenase activity
BC8716_04265	COG1082	Xylose isomerase domain protein TIM barrel
BC8716_04270	COG3962	Belongs to the TPP enzyme family
BC8716_04275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC8716_04280	COG3718	enzyme involved in inositol metabolism
BC8716_04285	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_04290	COG1349	DNA-binding transcription factor activity
BC8716_04295	COG2814	Major facilitator Superfamily
BC8716_04300	COG1309	transcriptional regulator
BC8716_04305	COG2076	Multidrug Resistance protein
BC8716_04310	COG2076	Multidrug Resistance protein
BC8716_04315	COG3279	Response regulator of the LytR AlgR family
BC8716_04335	COG1131	(ABC) transporter
BC8716_04340	COG1486	melibiose metabolic process
BC8716_04345	COG4214	carbohydrate transport
BC8716_04350	COG1129	ABC transporter
BC8716_04355	COG4213	ABC transporter substrate-binding protein
BC8716_04360	COG2160	L-arabinose isomerase activity
BC8716_04365	COG1069	ribulokinase activity
BC8716_04375	COG0371	Dehydrogenase
BC8716_04380	COG0647	UMP catabolic process
BC8716_04385	COG2207	Transcriptional regulator
BC8716_04395	COG5578	integral membrane protein
BC8716_04400	COG0395	ABC-type sugar transport system, permease component
BC8716_04405	COG1175	transmembrane transport
BC8716_04420	COG0395	ABC-type sugar transport system, permease component
BC8716_04425	COG1175	transmembrane transport
BC8716_04435	COG3401	FG-GAP repeat protein
BC8716_04450	COG0745	RESPONSE REGULATOR receiver
BC8716_04455	COG5002	protein histidine kinase activity
BC8716_04465	COG0395	ABC-type sugar transport system, permease component
BC8716_04470	COG1175	transmembrane transport
BC8716_04475	COG1653	transport
BC8716_04480	COG2207	Transcriptional regulator
BC8716_04480	COG4753	response regulator
BC8716_04485	COG2972	Histidine kinase
BC8716_04495	COG1312	Catalyzes the dehydration of D-mannonate
BC8716_04505	COG0673	inositol 2-dehydrogenase activity
BC8716_04510	COG2207	Transcriptional regulator
BC8716_04515	COG2814	Major facilitator Superfamily
BC8716_04520	COG3254	rhamnose metabolic process
BC8716_04525	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_04525	COG3347	Dehydrogenase
BC8716_04530	COG1070	Carbohydrate kinase
BC8716_04530	COG4806	L-rhamnose isomerase
BC8716_04560	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_04570	COG0726	polysaccharide deacetylase
BC8716_04575	COG0673	inositol 2-dehydrogenase activity
BC8716_04585	COG0584	glycerophosphoryl diester phosphodiesterase
BC8716_04590	COG0395	ABC-type sugar transport system, permease component
BC8716_04595	COG4209	transmembrane transport
BC8716_04600	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC8716_04620	COG0584	glycerophosphoryl diester phosphodiesterase
BC8716_04625	COG1653	transport
BC8716_04630	COG0395	ABC-type sugar transport system, permease component
BC8716_04635	COG1175	transmembrane transport
BC8716_04640	COG3842	ATPase activity
BC8716_04645	COG0584	glycerophosphoryl diester phosphodiesterase
BC8716_04650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC8716_04650	COG1017	nitric oxide dioxygenase activity
BC8716_04655	COG1959	2 iron, 2 sulfur cluster binding
BC8716_04670	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_04675	COG0183	Belongs to the thiolase family
BC8716_04680	COG0318	PFAM AMP-dependent synthetase and ligase
BC8716_04685	COG0318	PFAM AMP-dependent synthetase and ligase
BC8716_04700	COG2226	methyltransferase
BC8716_04705	COG0515	serine threonine protein kinase
BC8716_04715	COG3842	ATPase activity
BC8716_04720	COG0395	ABC-type sugar transport system, permease component
BC8716_04725	COG1175	transmembrane transport
BC8716_04740	COG1917	Cupin 2, conserved barrel domain protein
BC8716_04745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC8716_04750	COG0456	acetyltransferase
BC8716_04760	COG0697	spore germination
BC8716_04765	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_04770	COG1454	alcohol dehydrogenase
BC8716_04775	COG2066	Belongs to the glutaminase family
BC8716_04780	COG2610	gluconate transmembrane transporter activity
BC8716_04790	COG3829	transcription factor binding
BC8716_04790	COG3290	protein histidine kinase activity
BC8716_04810	COG1063	alcohol dehydrogenase
BC8716_04815	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BC8716_04835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BC8716_04840	COG0395	ABC-type sugar transport system, permease component
BC8716_04845	COG1175	transmembrane transport
BC8716_04850	COG1940	carbohydrate kinase activity
BC8716_04855	COG2723	6-phospho-beta-galactosidase activity
BC8716_04860	COG1609	Transcriptional regulator
BC8716_04870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_04870	COG1263	PTS System
BC8716_04875	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BC8716_04895	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BC8716_04900	COG1737	Transcriptional regulator
BC8716_04905	COG1132	(ABC) transporter
BC8716_04910	COG0789	Transcriptional regulator
BC8716_04915	COG1609	Transcriptional regulator
BC8716_04945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BC8716_04945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BC8716_04950	COG0628	permease
BC8716_04955	COG1528	Iron-storage protein
BC8716_04970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC8716_04975	COG2267	carboxylic ester hydrolase activity
BC8716_04980	COG0569	domain protein
BC8716_04985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC8716_05010	COG1051	belongs to the nudix hydrolase family
BC8716_05030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC8716_05035	COG0697	spore germination
BC8716_05045	COG0180	Tryptophanyl-tRNA synthetase
BC8716_05050	COG2226	methyltransferase
BC8716_05065	COG2072	flavoprotein involved in K transport
BC8716_05100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BC8716_05125	COG1136	(ABC) transporter
BC8716_05125	COG0577	efflux transmembrane transporter activity
BC8716_05135	COG2814	Major facilitator Superfamily
BC8716_05140	COG1309	transcriptional regulator
BC8716_05150	COG0745	RESPONSE REGULATOR receiver
BC8716_05155	COG0577	efflux transmembrane transporter activity
BC8716_05160	COG1136	(ABC) transporter
BC8716_05165	COG1819	glycosyl
BC8716_05170	COG1396	sequence-specific DNA binding
BC8716_05190	COG1917	Cupin 2, conserved barrel domain protein
BC8716_05190	COG2207	Transcriptional regulator
BC8716_05195	COG2723	6-phospho-beta-galactosidase activity
BC8716_05200	COG2190	(PTS) system
BC8716_05210	COG1263	PTS System
BC8716_05210	COG2190	(PTS) system
BC8716_05210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_05215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BC8716_05225	COG3959	Transketolase, thiamine diphosphate binding domain
BC8716_05235	COG1609	Transcriptional regulator
BC8716_05240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BC8716_05250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC8716_05260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BC8716_05265	COG5662	AntiSigma factor
BC8716_05270	COG1595	DNA-templated transcription, initiation
BC8716_05320	COG0747	negative chemotaxis
BC8716_05325	COG2755	lipolytic protein G-D-S-L family
BC8716_05330	COG1063	alcohol dehydrogenase
BC8716_05365	COG2211	Major facilitator Superfamily
BC8716_05370	COG3829	transcription factor binding
BC8716_05370	COG3290	protein histidine kinase activity
BC8716_05375	COG4948	Mandelate Racemase Muconate Lactonizing
BC8716_05385	COG0789	Transcriptional regulator
BC8716_05405	COG0789	Transcriptional regulator
BC8716_05445	COG0726	polysaccharide deacetylase
BC8716_05460	COG1737	Transcriptional regulator
BC8716_05475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC8716_05490	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC8716_05510	COG0489	protein tyrosine kinase activity
BC8716_05515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_05515	COG1263	PTS System
BC8716_05515	COG2190	(PTS) system
BC8716_05520	COG3711	transcriptional antiterminator
BC8716_05525	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC8716_05550	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BC8716_05555	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BC8716_05560	COG0101	tRNA pseudouridine synthase activity
BC8716_05570	COG1122	ATPase activity
BC8716_05575	COG1122	ATPase activity
BC8716_05580	COG0203	ribosomal protein L17
BC8716_05585	COG0202	RNA polymerase activity
BC8716_05590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BC8716_05595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BC8716_05600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BC8716_05605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BC8716_05610	COG0024	Methionine aminopeptidase
BC8716_05615	COG0563	adenylate kinase activity
BC8716_05620	COG0201	protein transport
BC8716_05625	COG0200	Binds to the 23S rRNA
BC8716_05630	COG1841	ribosomal large subunit assembly
BC8716_05635	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BC8716_05640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BC8716_05645	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BC8716_05650	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BC8716_05655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC8716_05660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BC8716_05665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BC8716_05670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BC8716_05675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BC8716_05680	COG0255	Belongs to the universal ribosomal protein uL29 family
BC8716_05685	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BC8716_05690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BC8716_05695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BC8716_05700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BC8716_05705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BC8716_05710	COG0089	rRNA binding
BC8716_05715	COG0088	Forms part of the polypeptide exit tunnel
BC8716_05720	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BC8716_05725	COG0051	transcription antitermination factor activity, RNA binding
BC8716_05730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BC8716_05735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BC8716_05740	COG0049	tRNA binding
BC8716_05745	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BC8716_05750	COG1358	cellular component organization or biogenesis
BC8716_05755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BC8716_05760	COG0085	RNA polymerase activity
BC8716_05765	COG2813	Specifically methylates the guanine in position
BC8716_05770	COG0222	ribosome binding
BC8716_05775	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BC8716_05780	COG0081	regulation of translation
BC8716_05785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BC8716_05790	COG0250	Participates in transcription elongation, termination and antitermination
BC8716_05795	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC8716_05810	COG3688	RNA-binding protein containing a PIN domain
BC8716_05815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC8716_05825	COG0215	cysteine-tRNA ligase activity
BC8716_05830	COG1045	serine acetyltransferase
BC8716_05835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BC8716_05840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BC8716_05845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BC8716_05850	COG4956	integral membrane protein (PIN domain superfamily)
BC8716_05855	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BC8716_05860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BC8716_05865	COG0542	response to heat
BC8716_05870	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BC8716_05875	COG3880	PFAM UvrB UvrC protein
BC8716_05960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BC8716_05965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC8716_05970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BC8716_05975	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BC8716_05980	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BC8716_05985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC8716_05990	COG0512	Glutamine amidotransferase of anthranilate synthase
BC8716_05995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BC8716_06000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC8716_06005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BC8716_06010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BC8716_06025	COG0037	tRNA processing
BC8716_06030	COG0515	serine threonine protein kinase
BC8716_06035	COG2304	oxidoreductase activity
BC8716_06040	COG2208	phosphoserine phosphatase activity
BC8716_06045	COG2851	Citrate transporter
BC8716_06055	COG1098	S1 RNA binding domain
BC8716_06080	COG0492	ferredoxin-NADP+ reductase activity
BC8716_06085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC8716_06090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC8716_06095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC8716_06100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BC8716_06105	COG3956	TIGRFAM MazG family protein
BC8716_06110	COG2244	polysaccharide biosynthetic process
BC8716_06120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BC8716_06130	COG2002	toxin-antitoxin pair type II binding
BC8716_06135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BC8716_06145	COG0193	aminoacyl-tRNA hydrolase activity
BC8716_06150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BC8716_06155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BC8716_06160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BC8716_06165	COG2088	sporulation resulting in formation of a cellular spore
BC8716_06170	COG0251	oxidation-reduction process
BC8716_06175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC8716_06180	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BC8716_06190	COG4466	Protein conserved in bacteria
BC8716_06200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC8716_06205	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BC8716_06210	COG3584	3D domain protein
BC8716_06210	COG3583	domain protein
BC8716_06215	COG0084	hydrolase, TatD family'
BC8716_06230	COG0488	(ABC) transporter
BC8716_06235	COG3866	Pectate lyase
BC8716_06245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC8716_06245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC8716_06260	COG2002	toxin-antitoxin pair type II binding
BC8716_06265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BC8716_06270	COG2827	Endonuclease containing a URI domain
BC8716_06275	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BC8716_06280	COG4467	Involved in initiation control of chromosome replication
BC8716_06285	COG1774	PSP1 C-terminal conserved region
BC8716_06290	COG0470	DNA polymerase III
BC8716_06295	COG3870	Protein conserved in bacteria
BC8716_06300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BC8716_06305	COG1982	Orn Lys Arg decarboxylase major
BC8716_06315	COG1078	dGTPase activity
BC8716_06320	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_06330	COG2204	response regulator
BC8716_06335	COG4191	Histidine kinase
BC8716_06370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BC8716_06375	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BC8716_06380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BC8716_06390	COG0740	serine-type endopeptidase activity
BC8716_06400	COG0590	tRNA wobble adenosine to inosine editing
BC8716_06410	COG0747	negative chemotaxis
BC8716_06425	COG0444	Belongs to the ABC transporter superfamily
BC8716_06430	COG4608	Belongs to the ABC transporter superfamily
BC8716_06440	COG0765	amino acid transport
BC8716_06445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC8716_06455	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_06475	COG0006	proline dipeptidase activity
BC8716_06490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC8716_06495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC8716_06500	COG3829	transcription factor binding
BC8716_06505	COG2508	Transcriptional regulator
BC8716_06510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC8716_06515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BC8716_06525	COG0517	IMP dehydrogenase activity
BC8716_06525	COG0516	GMP reductase activity
BC8716_06555	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_06560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC8716_06565	COG0187	DNA topoisomerase II activity
BC8716_06575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BC8716_06580	COG2501	S4 domain
BC8716_06585	COG0592	DNA-directed DNA polymerase activity
BC8716_06590	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BC8716_06595	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BC8716_06600	COG0594	ribonuclease P activity
BC8716_06605	COG0706	membrane insertase activity
BC8716_06610	COG1847	R3H domain protein
BC8716_06615	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BC8716_06620	COG0445	tRNA wobble uridine modification
BC8716_06625	COG0357	Ribosomal RNA small subunit methyltransferase G
BC8716_06630	COG1475	DNA binding
BC8716_06635	COG1192	Involved in chromosome partitioning
BC8716_06640	COG1475	DNA binding
BC8716_06645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC8716_06655	COG3949	Membrane
BC8716_06660	COG4481	Protein conserved in bacteria
BC8716_06665	COG0012	GTP binding
BC8716_06670	COG0360	Binds together with S18 to 16S ribosomal RNA
BC8716_06675	COG0629	single-stranded DNA binding
BC8716_06680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BC8716_06690	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BC8716_06695	COG0359	binds to the 23S rRNA
BC8716_06700	COG0305	Participates in initiation and elongation during chromosome replication
BC8716_06705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BC8716_06735	COG0745	RESPONSE REGULATOR receiver
BC8716_06740	COG5002	protein histidine kinase activity
BC8716_06750	COG4853	Protein conserved in bacteria
BC8716_06755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BC8716_06760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC8716_06770	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BC8716_06775	COG0210	DNA helicase
BC8716_06785	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BC8716_06820	COG1063	alcohol dehydrogenase
BC8716_06830	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BC8716_06840	COG0235	Class ii aldolase
BC8716_06870	COG0601	transmembrane transport
BC8716_06880	COG0444	Belongs to the ABC transporter superfamily
BC8716_06885	COG4608	Belongs to the ABC transporter superfamily
BC8716_06905	COG3275	phosphorelay sensor kinase activity
BC8716_06910	COG3279	Response regulator of the LytR AlgR family
BC8716_06915	COG1966	Carbon starvation protein
BC8716_06940	COG1595	DNA-templated transcription, initiation
BC8716_06955	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BC8716_06960	COG1802	Transcriptional regulator
BC8716_06965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC8716_06980	COG0372	Belongs to the citrate synthase family
BC8716_06985	COG0583	DNA-binding transcription factor activity
BC8716_07000	COG2186	Transcriptional regulator
BC8716_07005	COG2186	Transcriptional regulator
BC8716_07010	COG0277	FAD linked oxidase domain protein
BC8716_07015	COG0247	lactate metabolic process
BC8716_07020	COG0579	oxidoreductase
BC8716_07025	COG2508	Transcriptional regulator
BC8716_07030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BC8716_07035	COG0402	S-adenosylhomocysteine deaminase activity
BC8716_07045	COG2182	Extracellular solute-binding protein
BC8716_07050	COG1175	transmembrane transport
BC8716_07055	COG3833	ABC-type maltose transport systems, permease component
BC8716_07060	COG1609	Transcriptional regulator
BC8716_07065	COG2031	fatty acid transporter
BC8716_07070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BC8716_07075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC8716_07085	COG0346	lactoylglutathione lyase activity
BC8716_07100	COG0813	purine-nucleoside phosphorylase activity
BC8716_07105	COG0523	cobalamin synthesis protein
BC8716_07110	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC8716_07115	COG1193	negative regulation of DNA recombination
BC8716_07120	COG1307	EDD domain protein, DegV family
BC8716_07150	COG2807	transmembrane transport
BC8716_07160	COG0745	RESPONSE REGULATOR receiver
BC8716_07180	COG2154	pterin-4-alpha-carbinolamine dehydratase
BC8716_07185	COG0733	neurotransmitter:sodium symporter activity
BC8716_07220	COG1114	Component of the transport system for branched-chain amino acids
BC8716_07235	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BC8716_07240	COG3290	protein histidine kinase activity
BC8716_07245	COG4565	transcriptional regulatory protein
BC8716_07250	COG0471	metal ion transport
BC8716_07265	COG1733	regulation of RNA biosynthetic process
BC8716_07270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC8716_07280	COG1116	anion transmembrane transporter activity
BC8716_07285	COG1137	ATPase activity
BC8716_07300	COG0745	RESPONSE REGULATOR receiver
BC8716_07300	COG2972	Histidine kinase
BC8716_07310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC8716_07310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC8716_07340	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BC8716_07350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC8716_07355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BC8716_07360	COG5504	Zn-dependent protease
BC8716_07365	COG0789	Transcriptional regulator
BC8716_07370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC8716_07375	COG1733	regulation of RNA biosynthetic process
BC8716_07380	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BC8716_07385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BC8716_07390	COG1597	lipid kinase activity
BC8716_07395	COG2323	membrane
BC8716_07400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC8716_07405	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BC8716_07410	COG1132	(ABC) transporter
BC8716_07415	COG0753	catalase activity
BC8716_07425	COG2814	Major facilitator Superfamily
BC8716_07430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BC8716_07435	COG0840	transmembrane signaling receptor activity
BC8716_07445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC8716_07450	COG0561	phosphatase activity
BC8716_07455	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC8716_07460	COG1121	(ABC) transporter
BC8716_07465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC8716_07465	COG1321	iron dependent repressor
BC8716_07470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC8716_07485	COG2814	Major facilitator Superfamily
BC8716_07490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BC8716_07495	COG0551	DNA topoisomerase type I activity
BC8716_07495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC8716_07500	COG1785	Belongs to the alkaline phosphatase family
BC8716_07505	COG0024	Methionine aminopeptidase
BC8716_07510	COG2268	Band 7 protein
BC8716_07525	COG0723	plastoquinol--plastocyanin reductase activity
BC8716_07525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC8716_07530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BC8716_07535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC8716_07540	COG0513	Belongs to the DEAD box helicase family
BC8716_07575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC8716_07590	COG2986	histidine ammonia-lyase
BC8716_07595	COG0351	phosphomethylpyrimidine kinase
BC8716_07605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BC8716_07615	COG0004	ammonium transporteR
BC8716_07635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC8716_07640	COG0456	acetyltransferase
BC8716_07645	COG2363	Small membrane protein
BC8716_07655	COG3773	Cell wall hydrolase
BC8716_07665	COG1725	Transcriptional regulator
BC8716_07670	COG1131	(ABC) transporter
BC8716_07675	COG4152	abc transporter atp-binding protein
BC8716_07680	COG1668	transmembrane transport
BC8716_07700	COG1024	Enoyl-CoA hydratase
BC8716_07705	COG0280	phosphate acetyltransferase
BC8716_07710	COG0095	Lipoate-protein ligase
BC8716_07715	COG1301	dicarboxylic acid transport
BC8716_07720	COG1078	dGTPase activity
BC8716_07725	COG3465	dGTPase activity
BC8716_07735	COG5577	PFAM Coat F domain
BC8716_07745	COG3764	Sortase (surface protein transpeptidase)
BC8716_07760	COG1164	Oligoendopeptidase f
BC8716_07770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC8716_07775	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BC8716_07780	COG0010	Belongs to the arginase family
BC8716_07790	COG0018	arginyl-trna synthetase
BC8716_07795	COG2839	Protein conserved in bacteria
BC8716_07800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC8716_07805	COG0247	lactate metabolic process
BC8716_07805	COG2181	nitrate reductase activity
BC8716_07810	COG0183	Belongs to the thiolase family
BC8716_07815	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC8716_07820	COG1960	acyl-CoA dehydrogenase activity
BC8716_07830	COG3343	RNA polymerase activity
BC8716_07835	COG0504	CTP synthase activity
BC8716_07850	COG0191	fructose-bisphosphate aldolase activity
BC8716_07855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BC8716_07860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BC8716_07865	COG1494	fructose-1,6-bisphosphatase
BC8716_07870	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BC8716_07875	COG0254	rRNA binding
BC8716_07880	COG1435	thymidine kinase activity
BC8716_07890	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC8716_07895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BC8716_07915	COG0009	L-threonylcarbamoyladenylate synthase
BC8716_07925	COG1971	Probably functions as a manganese efflux pump
BC8716_07935	COG5278	phosphoserine phosphatase activity
BC8716_07935	COG0840	transmembrane signaling receptor activity
BC8716_07940	COG0698	ribose 5-phosphate isomerase
BC8716_07945	COG4475	Protein of unknown function (DUF436)
BC8716_07950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BC8716_07955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BC8716_07960	COG0456	acetyltransferase
BC8716_07965	COG1404	Belongs to the peptidase S8 family
BC8716_07980	COG0356	it plays a direct role in the translocation of protons across the membrane
BC8716_07985	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC8716_07990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BC8716_07995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC8716_08000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BC8716_08005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BC8716_08010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BC8716_08015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BC8716_08030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BC8716_08035	COG2385	sporulation resulting in formation of a cellular spore
BC8716_08040	COG0739	heme binding
BC8716_08045	COG2076	Multidrug Resistance protein
BC8716_08050	COG2076	Multidrug Resistance protein
BC8716_08055	COG1609	Transcriptional regulator
BC8716_08060	COG1077	Cell shape determining protein MreB Mrl
BC8716_08065	COG4786	Flagellar basal body rod
BC8716_08070	COG4786	Flagellar basal body rod
BC8716_08095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BC8716_08105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BC8716_08120	COG2318	DinB family
BC8716_08130	COG0791	NLP P60 protein
BC8716_08130	COG1388	LysM domain
BC8716_08135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BC8716_08145	COG2388	GCN5-related N-acetyl-transferase
BC8716_08150	COG1316	TRANSCRIPTIONal
BC8716_08160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC8716_08165	COG0772	Belongs to the SEDS family
BC8716_08170	COG2814	Major facilitator Superfamily
BC8716_08175	COG0537	adenosine 5'-monophosphoramidase activity
BC8716_08180	COG0590	tRNA wobble adenosine to inosine editing
BC8716_08195	COG1280	lysine exporter protein (LysE YggA)
BC8716_08205	COG1316	TRANSCRIPTIONal
BC8716_08210	COG3944	biosynthesis protein
BC8716_08215	COG0489	protein tyrosine kinase activity
BC8716_08220	COG4464	protein tyrosine phosphatase activity
BC8716_08255	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_08260	COG2910	NAD(P)H-binding
BC8716_08270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC8716_08295	COG0493	'glutamate synthase
BC8716_08300	COG1349	DNA-binding transcription factor activity
BC8716_08310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_08310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_08310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_08315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_08330	COG2376	Dihydroxyacetone kinase
BC8716_08340	COG0149	triose-phosphate isomerase activity
BC8716_08360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC8716_08365	COG3708	Transcriptional regulator
BC8716_08365	COG2207	Transcriptional regulator
BC8716_08370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC8716_08380	COG0395	ABC-type sugar transport system, permease component
BC8716_08385	COG1175	transmembrane transport
BC8716_08395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC8716_08400	COG1984	allophanate hydrolase subunit 2
BC8716_08405	COG1914	H( )-stimulated, divalent metal cation uptake system
BC8716_08410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BC8716_08435	COG0778	Nitroreductase
BC8716_08440	COG1609	Transcriptional regulator
BC8716_08445	COG1621	beta-fructofuranosidase activity
BC8716_08450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_08450	COG1263	PTS System
BC8716_08460	COG0300	oxidoreductase activity
BC8716_08480	COG1959	2 iron, 2 sulfur cluster binding
BC8716_08485	COG0537	adenosine 5'-monophosphoramidase activity
BC8716_08500	COG1116	anion transmembrane transporter activity
BC8716_08505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC8716_08520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC8716_08530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BC8716_08535	COG2068	MobA-Related Protein
BC8716_08545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BC8716_08550	COG2080	2 iron, 2 sulfur cluster binding
BC8716_08555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC8716_08560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC8716_08565	COG2508	Transcriptional regulator
BC8716_08580	COG1288	antiporter activity
BC8716_08585	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC8716_08590	COG0154	amidase activity
BC8716_08595	COG3361	conserved protein (COG2071)
BC8716_08650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_08665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC8716_08670	COG1116	anion transmembrane transporter activity
BC8716_08675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC8716_08690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BC8716_08695	COG5658	integral membrane protein
BC8716_08700	COG0640	Transcriptional regulator
BC8716_08705	COG0583	DNA-binding transcription factor activity
BC8716_08715	COG1115	amino acid carrier protein
BC8716_08720	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_08775	COG0697	spore germination
BC8716_08780	COG0814	amino acid
BC8716_08805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC8716_08810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC8716_08820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BC8716_08835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC8716_08850	COG1216	Glycosyl transferase, family 2
BC8716_08850	COG0463	Glycosyl transferase, family 2
BC8716_08855	COG2244	polysaccharide biosynthetic process
BC8716_08860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BC8716_08880	COG2207	Transcriptional regulator
BC8716_08890	COG4221	oxidoreductase activity
BC8716_08895	COG2249	NAD(P)H dehydrogenase (quinone) activity
BC8716_08900	COG1733	regulation of RNA biosynthetic process
BC8716_08965	COG1486	melibiose metabolic process
BC8716_08980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC8716_08980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC8716_08985	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC8716_08995	COG2971	BadF BadG BcrA BcrD
BC8716_09005	COG0583	DNA-binding transcription factor activity
BC8716_09015	COG0747	negative chemotaxis
BC8716_09020	COG0601	transmembrane transport
BC8716_09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC8716_09030	COG0444	Belongs to the ABC transporter superfamily
BC8716_09035	COG4608	Belongs to the ABC transporter superfamily
BC8716_09040	COG1473	amidohydrolase
BC8716_09045	COG0471	metal ion transport
BC8716_09055	COG1473	amidohydrolase
BC8716_09070	COG1840	ABC-type Fe3 transport system, periplasmic component
BC8716_09075	COG3842	ATPase activity
BC8716_09085	COG2972	Histidine kinase
BC8716_09090	COG2207	Transcriptional regulator
BC8716_09090	COG4753	response regulator
BC8716_09100	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BC8716_09105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC8716_09115	COG3409	Peptidoglycan-binding domain 1 protein
BC8716_09125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_09130	COG1464	Belongs to the NlpA lipoprotein family
BC8716_09135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC8716_09140	COG2011	ABC-type metal ion transport system permease component
BC8716_09145	COG1464	Belongs to the NlpA lipoprotein family
BC8716_09155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_09160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_09170	COG0765	amino acid transport
BC8716_09175	COG1126	abc transporter atp-binding protein
BC8716_09185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BC8716_09195	COG1473	amidohydrolase
BC8716_09200	COG0431	NADPH-dependent FMN reductase
BC8716_09210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_09215	COG4172	Belongs to the ABC transporter superfamily
BC8716_09225	COG0601	transmembrane transport
BC8716_09230	COG0747	negative chemotaxis
BC8716_09235	COG0583	DNA-binding transcription factor activity
BC8716_09250	COG1741	Belongs to the pirin family
BC8716_09255	COG1733	regulation of RNA biosynthetic process
BC8716_09260	COG0402	S-adenosylhomocysteine deaminase activity
BC8716_09275	COG3546	catalase activity
BC8716_09295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC8716_09300	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BC8716_09310	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_09320	COG0318	PFAM AMP-dependent synthetase and ligase
BC8716_09335	COG2814	Major facilitator Superfamily
BC8716_09340	COG1063	alcohol dehydrogenase
BC8716_09345	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_09350	COG1349	DNA-binding transcription factor activity
BC8716_09355	COG0698	ribose 5-phosphate isomerase
BC8716_09360	COG2376	Dihydroxyacetone kinase
BC8716_09365	COG2376	Dihydroxyacetone kinase
BC8716_09370	COG1494	fructose-1,6-bisphosphatase
BC8716_09375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC8716_09395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC8716_09400	COG1609	Transcriptional regulator
BC8716_09425	COG1175	transmembrane transport
BC8716_09440	COG2972	Histidine kinase
BC8716_09445	COG2207	Transcriptional regulator
BC8716_09445	COG4753	response regulator
BC8716_09470	COG4682	membrane
BC8716_09535	COG2207	Transcriptional regulator
BC8716_09535	COG4753	response regulator
BC8716_09540	COG2972	Histidine kinase
BC8716_09545	COG1653	transport
BC8716_09555	COG0395	ABC-type sugar transport system, permease component
BC8716_09560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC8716_09575	COG1263	PTS System
BC8716_09575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_09580	COG1737	Transcriptional regulator
BC8716_09605	COG0456	acetyltransferase
BC8716_09615	COG1349	DNA-binding transcription factor activity
BC8716_09625	COG3414	Phosphotransferase system galactitol-specific IIB component
BC8716_09630	COG3775	system Galactitol-specific IIC component
BC8716_09635	COG1063	alcohol dehydrogenase
BC8716_09645	COG2315	Protein conserved in bacteria
BC8716_09650	COG1469	GTP cyclohydrolase I activity
BC8716_09660	COG3655	Transcriptional regulator
BC8716_09665	COG3739	integral membrane protein
BC8716_09685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BC8716_09700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_09700	COG2190	(PTS) system
BC8716_09700	COG1263	PTS System
BC8716_09710	COG2972	Histidine kinase
BC8716_09710	COG0745	RESPONSE REGULATOR receiver
BC8716_09715	COG3279	Response regulator of the LytR AlgR family
BC8716_09730	COG1396	sequence-specific DNA binding
BC8716_09740	COG0747	negative chemotaxis
BC8716_09745	COG0601	transmembrane transport
BC8716_09755	COG0444	Belongs to the ABC transporter superfamily
BC8716_09760	COG4608	Belongs to the ABC transporter superfamily
BC8716_09765	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC8716_09775	COG1132	(ABC) transporter
BC8716_09805	COG1131	(ABC) transporter
BC8716_09820	COG0745	RESPONSE REGULATOR receiver
BC8716_09825	COG5002	protein histidine kinase activity
BC8716_09875	COG1609	Transcriptional regulator
BC8716_09880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC8716_09885	COG1869	D-ribose catabolic process
BC8716_09890	COG1129	ABC transporter
BC8716_09895	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC8716_09900	COG1879	ABC-type sugar transport system periplasmic component
BC8716_09955	COG1376	ErfK ybiS ycfS ynhG family protein
BC8716_09960	COG2312	Erythromycin esterase
BC8716_09970	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_09985	COG2207	Transcriptional regulator
BC8716_09990	COG1131	(ABC) transporter
BC8716_10000	COG0562	UDP-galactopyranose mutase
BC8716_10025	COG0463	Glycosyl transferase, family 2
BC8716_10035	COG1378	Sugar-specific transcriptional regulator TrmB
BC8716_10040	COG0697	spore germination
BC8716_10065	COG1609	Transcriptional regulator
BC8716_10070	COG2182	Extracellular solute-binding protein
BC8716_10075	COG1175	transmembrane transport
BC8716_10080	COG3833	ABC-type maltose transport systems, permease component
BC8716_10085	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BC8716_10090	COG1874	Beta-galactosidase
BC8716_10105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC8716_10115	COG0789	Transcriptional regulator
BC8716_10135	COG0693	protein deglycase activity
BC8716_10145	COG0191	fructose-bisphosphate aldolase activity
BC8716_10150	COG3037	sugar-specific permease SgaT UlaA
BC8716_10160	COG0205	6-phosphofructokinase activity
BC8716_10165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_10180	COG1136	(ABC) transporter
BC8716_10185	COG0577	efflux transmembrane transporter activity
BC8716_10195	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BC8716_10200	COG0697	spore germination
BC8716_10230	COG1414	Transcriptional regulator
BC8716_10235	COG2207	Transcriptional regulator
BC8716_10235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC8716_10240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC8716_10245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC8716_10250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC8716_10255	COG2819	hydrolase of the alpha beta superfamily
BC8716_10270	COG2602	Beta-lactamase
BC8716_10280	COG0840	transmembrane signaling receptor activity
BC8716_10285	COG1609	Transcriptional regulator
BC8716_10295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC8716_10300	COG2207	Transcriptional regulator
BC8716_10310	COG2826	transposase and inactivated derivatives, IS30 family
BC8716_10315	COG1609	Transcriptional regulator
BC8716_10320	COG0673	inositol 2-dehydrogenase activity
BC8716_10335	COG0395	ABC-type sugar transport system, permease component
BC8716_10340	COG1082	Xylose isomerase domain protein TIM barrel
BC8716_10355	COG2197	response regulator
BC8716_10375	COG1366	Belongs to the anti-sigma-factor antagonist family
BC8716_10400	COG2720	vancomycin resistance protein
BC8716_10410	COG2135	peptidase activity
BC8716_10440	COG0542	response to heat
BC8716_10445	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC8716_10480	COG2311	Membrane
BC8716_10485	COG1940	carbohydrate kinase activity
BC8716_10495	COG1175	transmembrane transport
BC8716_10500	COG0395	ABC-type sugar transport system, permease component
BC8716_10505	COG0673	inositol 2-dehydrogenase activity
BC8716_10510	COG0673	inositol 2-dehydrogenase activity
BC8716_10520	COG0596	Alpha beta hydrolase
BC8716_10530	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_10540	COG0477	Major facilitator Superfamily
BC8716_10545	COG1309	transcriptional regulator
BC8716_10550	COG2226	methyltransferase
BC8716_10555	COG1063	alcohol dehydrogenase
BC8716_10570	COG2329	Antibiotic biosynthesis monooxygenase
BC8716_10575	COG5386	Cell surface protein
BC8716_10580	COG5386	Cell surface protein
BC8716_10595	COG1120	ATPase activity
BC8716_10600	COG4509	Sortase family
BC8716_10605	COG1253	flavin adenine dinucleotide binding
BC8716_10620	COG3546	catalase activity
BC8716_10625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC8716_10630	COG1063	alcohol dehydrogenase
BC8716_10635	COG1587	Uroporphyrinogen-III synthase
BC8716_10650	COG1131	(ABC) transporter
BC8716_10660	COG1309	transcriptional regulator
BC8716_10665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC8716_10680	COG2323	membrane
BC8716_10690	COG0583	DNA-binding transcription factor activity
BC8716_10695	COG0431	NADPH-dependent FMN reductase
BC8716_10710	COG1116	anion transmembrane transporter activity
BC8716_10715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_10720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC8716_10725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC8716_10730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC8716_10735	COG0583	DNA-binding transcription factor activity
BC8716_10740	COG0640	Transcriptional regulator
BC8716_10750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BC8716_10765	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_10770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BC8716_10780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BC8716_10785	COG1653	transport
BC8716_10800	COG1609	Transcriptional regulator
BC8716_10835	COG4585	Histidine kinase
BC8716_10840	COG2197	response regulator
BC8716_10845	COG4149	molybdate abc transporter
BC8716_10850	COG0725	ABC transporter, periplasmic molybdate-binding protein
BC8716_10855	COG1609	Transcriptional regulator
BC8716_10865	COG1175	transmembrane transport
BC8716_10880	COG3534	alpha-L-arabinofuranosidase
BC8716_10890	COG3507	Belongs to the glycosyl hydrolase 43 family
BC8716_10895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BC8716_10905	COG1682	transport, permease protein
BC8716_10910	COG1134	teichoic acid transport
BC8716_10915	COG1694	Mazg nucleotide pyrophosphohydrolase
BC8716_10935	COG3328	transposase activity
BC8716_10945	COG0512	Glutamine amidotransferase of anthranilate synthase
BC8716_10945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC8716_10955	COG1216	Glycosyl transferase, family 2
BC8716_10960	COG2814	Major facilitator Superfamily
BC8716_10980	COG1609	Transcriptional regulator
BC8716_10995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BC8716_11000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BC8716_11010	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BC8716_11020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BC8716_11030	COG2217	Heavy metal translocating P-type atpase
BC8716_11045	COG3414	Phosphotransferase system galactitol-specific IIB component
BC8716_11050	COG3775	system Galactitol-specific IIC component
BC8716_11055	COG1063	alcohol dehydrogenase
BC8716_11060	COG1063	alcohol dehydrogenase
BC8716_11075	COG1388	LysM domain
BC8716_11080	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC8716_11085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_11085	COG1263	PTS System
BC8716_11090	COG3711	transcriptional antiterminator
BC8716_11100	COG2197	response regulator
BC8716_11105	COG4585	Histidine kinase
BC8716_11120	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BC8716_11125	COG1228	amidohydrolase
BC8716_11135	COG0402	S-adenosylhomocysteine deaminase activity
BC8716_11165	COG1078	dGTPase activity
BC8716_11190	COG1309	transcriptional regulator
BC8716_11215	COG1418	mRNA catabolic process
BC8716_11220	COG0124	histidyl-tRNA synthetase
BC8716_11230	COG2261	transglycosylase associated protein
BC8716_11240	COG3344	reverse transcriptase
BC8716_11260	COG1653	transport
BC8716_11270	COG0395	ABC-type sugar transport system, permease component
BC8716_11280	COG0501	Belongs to the peptidase M48B family
BC8716_11305	COG1263	PTS System
BC8716_11305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_11305	COG2190	(PTS) system
BC8716_11310	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BC8716_11315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BC8716_11325	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC8716_11325	COG2247	cell wall binding repeat
BC8716_11335	COG1368	sulfuric ester hydrolase activity
BC8716_11350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC8716_11355	COG0384	phenazine biosynthesis protein PhzF
BC8716_11365	COG0673	inositol 2-dehydrogenase activity
BC8716_11370	COG1917	Cupin 2, conserved barrel domain protein
BC8716_11370	COG2207	Transcriptional regulator
BC8716_11380	COG0673	inositol 2-dehydrogenase activity
BC8716_11390	COG1175	transmembrane transport
BC8716_11395	COG0395	ABC-type sugar transport system, permease component
BC8716_11405	COG2207	Transcriptional regulator
BC8716_11405	COG3708	Transcriptional regulator
BC8716_11415	COG0673	inositol 2-dehydrogenase activity
BC8716_11420	COG4977	sequence-specific DNA binding
BC8716_11425	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BC8716_11430	COG1175	transmembrane transport
BC8716_11435	COG0395	ABC-type sugar transport system, permease component
BC8716_11455	COG3420	alginic acid biosynthetic process
BC8716_11465	COG1309	transcriptional regulator
BC8716_11475	COG0583	DNA-binding transcription factor activity
BC8716_11480	COG3842	ATPase activity
BC8716_11485	COG1840	ABC-type Fe3 transport system, periplasmic component
BC8716_11490	COG1177	transmembrane transport
BC8716_11520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC8716_11545	COG1482	cell wall glycoprotein biosynthetic process
BC8716_11550	COG1968	undecaprenyl-diphosphatase activity
BC8716_11555	COG2270	Major facilitator Superfamily
BC8716_11560	COG3835	regulator
BC8716_11565	COG0277	FAD linked oxidase domain protein
BC8716_11570	COG0247	lactate metabolic process
BC8716_11575	COG1116	anion transmembrane transporter activity
BC8716_11580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC8716_11590	COG0456	acetyltransferase
BC8716_11595	COG1846	Transcriptional regulator
BC8716_11610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_11625	COG3730	PTS system glucitol sorbitol-specific
BC8716_11630	COG3732	PTS system glucitol sorbitol-specific
BC8716_11645	COG3344	reverse transcriptase
BC8716_11655	COG2217	Heavy metal translocating P-type atpase
BC8716_11660	COG0577	efflux transmembrane transporter activity
BC8716_11665	COG1136	(ABC) transporter
BC8716_11670	COG5002	protein histidine kinase activity
BC8716_11675	COG0745	RESPONSE REGULATOR receiver
BC8716_11690	COG1940	carbohydrate kinase activity
BC8716_11695	COG4187	Peptidase family M20/M25/M40
BC8716_11700	COG2814	Major facilitator Superfamily
BC8716_11705	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BC8716_11715	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BC8716_11720	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BC8716_11725	COG1349	DNA-binding transcription factor activity
BC8716_11730	COG1368	sulfuric ester hydrolase activity
BC8716_11735	COG0516	GMP reductase activity
BC8716_11770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BC8716_11785	COG1176	ABC-type spermidine putrescine transport system, permease component I
BC8716_11790	COG1957	nucleoside hydrolase
BC8716_11815	COG0589	response to stress
BC8716_11830	COG1105	Belongs to the carbohydrate kinase PfkB family
BC8716_11835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_11835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_11835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_11855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC8716_11875	COG1309	transcriptional regulator
BC8716_11880	COG0842	Transport permease protein
BC8716_11885	COG1131	(ABC) transporter
BC8716_11910	COG1473	amidohydrolase
BC8716_11915	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BC8716_11960	COG0438	transferase activity, transferring glycosyl groups
BC8716_11975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BC8716_11985	COG1215	transferase activity, transferring glycosyl groups
BC8716_11990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC8716_12060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC8716_12065	COG2169	Transcriptional regulator
BC8716_12070	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BC8716_12075	COG0673	inositol 2-dehydrogenase activity
BC8716_12080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BC8716_12085	COG0561	phosphatase activity
BC8716_12090	COG2318	DinB family
BC8716_12105	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_12110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BC8716_12120	COG2197	response regulator
BC8716_12125	COG4585	Histidine kinase
BC8716_12125	COG2203	Gaf domain
BC8716_12135	COG2112	serine threonine protein kinase
BC8716_12140	COG1959	2 iron, 2 sulfur cluster binding
BC8716_12150	COG0800	Aldolase
BC8716_12155	COG1476	TRANSCRIPTIONal
BC8716_12175	COG1131	(ABC) transporter
BC8716_12180	COG1725	Transcriptional regulator
BC8716_12200	COG1396	sequence-specific DNA binding
BC8716_12210	COG1472	Belongs to the glycosyl hydrolase 3 family
BC8716_12220	COG1175	transmembrane transport
BC8716_12225	COG0395	ABC-type sugar transport system, permease component
BC8716_12230	COG3842	ATPase activity
BC8716_12240	COG1609	Transcriptional regulator
BC8716_12245	COG4209	transmembrane transport
BC8716_12250	COG0395	ABC-type sugar transport system, permease component
BC8716_12260	COG1621	beta-fructofuranosidase activity
BC8716_12270	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_12275	COG3858	chitin binding
BC8716_12275	COG1388	LysM domain
BC8716_12285	COG1335	isochorismatase
BC8716_12290	COG4112	unkown
BC8716_12295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC8716_12300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC8716_12315	COG1215	transferase activity, transferring glycosyl groups
BC8716_12320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC8716_12325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BC8716_12335	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BC8716_12340	COG0463	Glycosyl transferase, family 2
BC8716_12340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BC8716_12345	COG1215	transferase activity, transferring glycosyl groups
BC8716_12345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BC8716_12350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC8716_12355	COG4193	domain, Protein
BC8716_12360	COG1316	TRANSCRIPTIONal
BC8716_12375	COG4608	Belongs to the ABC transporter superfamily
BC8716_12380	COG0601	transmembrane transport
BC8716_12390	COG4166	transmembrane transport
BC8716_12395	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BC8716_12400	COG1739	Uncharacterized protein family UPF0029
BC8716_12415	COG1307	EDD domain protein, DegV family
BC8716_12420	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BC8716_12435	COG2747	anti-sigma28 factor FlgM
BC8716_12445	COG4786	Flagellar basal body rod
BC8716_12445	COG1256	bacterial-type flagellum assembly
BC8716_12450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC8716_12455	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BC8716_12460	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BC8716_12465	COG1334	flagellar protein FlaG
BC8716_12470	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BC8716_12475	COG1516	flagellar protein fliS
BC8716_12490	COG1278	Cold shock
BC8716_12495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BC8716_12500	COG0653	protein targeting
BC8716_12505	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BC8716_12510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC8716_12515	COG2884	Cell division ATP-binding protein ftsE
BC8716_12520	COG2177	Part of the ABC transporter FtsEX involved in
BC8716_12525	COG0739	heme binding
BC8716_12530	COG0793	Belongs to the peptidase S41A family
BC8716_12530	COG3409	Peptidoglycan-binding domain 1 protein
BC8716_12545	COG0556	nucleotide-excision repair
BC8716_12550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC8716_12555	COG3595	metallopeptidase activity
BC8716_12560	COG1983	PspC domain protein
BC8716_12565	COG1950	PFAM Membrane protein of
BC8716_12570	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BC8716_12575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BC8716_12580	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC8716_12585	COG0546	phosphoglycolate phosphatase activity
BC8716_12590	COG0110	maltose O-acetyltransferase activity
BC8716_12595	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BC8716_12600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BC8716_12610	COG0131	Imidazoleglycerol-phosphate dehydratase
BC8716_12615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BC8716_12620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BC8716_12625	COG0107	imidazoleglycerol-phosphate synthase activity
BC8716_12630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BC8716_12630	COG0140	phosphoribosyl-ATP diphosphatase activity
BC8716_12640	COG2207	Transcriptional regulator
BC8716_12640	COG1917	Cupin 2, conserved barrel domain protein
BC8716_12645	COG0697	spore germination
BC8716_12650	COG2124	cytochrome p450
BC8716_12660	COG0492	ferredoxin-NADP+ reductase activity
BC8716_12665	COG1051	belongs to the nudix hydrolase family
BC8716_12670	COG1660	Displays ATPase and GTPase activities
BC8716_12675	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BC8716_12680	COG1481	regulation of sporulation
BC8716_12685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_12690	COG1174	glycine betaine transport
BC8716_12695	COG1732	Glycine betaine
BC8716_12700	COG1174	glycine betaine transport
BC8716_12705	COG1125	glycine betaine transport
BC8716_12705	COG0517	IMP dehydrogenase activity
BC8716_12715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC8716_12720	COG0740	serine-type endopeptidase activity
BC8716_12725	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BC8716_12755	COG0126	phosphoglycerate kinase activity
BC8716_12760	COG0149	triose-phosphate isomerase activity
BC8716_12765	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BC8716_12770	COG0148	phosphopyruvate hydratase activity
BC8716_12790	COG1695	Transcriptional regulator
BC8716_12795	COG1802	Transcriptional regulator
BC8716_12800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC8716_12805	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_12810	COG4948	Mandelate Racemase Muconate Lactonizing
BC8716_12835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC8716_12840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_12850	COG1647	Serine aminopeptidase, S33
BC8716_12855	COG0557	exoribonuclease II activity
BC8716_12860	COG2259	Doxx family
BC8716_12870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BC8716_12895	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BC8716_12910	COG4533	DNA binding
BC8716_12920	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC8716_12920	COG1024	Enoyl-CoA hydratase
BC8716_12925	COG0183	Belongs to the thiolase family
BC8716_12930	COG1960	acyl-CoA dehydrogenase activity
BC8716_12935	COG1393	Belongs to the ArsC family
BC8716_12940	COG0509	glycine decarboxylation via glycine cleavage system
BC8716_12945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC8716_12950	COG2011	ABC-type metal ion transport system permease component
BC8716_12955	COG1464	Belongs to the NlpA lipoprotein family
BC8716_12965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC8716_12970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC8716_12975	COG0396	ATPase activity
BC8716_12980	COG0719	Fe-S assembly protein
BC8716_12985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC8716_12990	COG0822	iron-sulfur transferase activity
BC8716_12995	COG0719	Fe-S assembly protein
BC8716_13000	COG0726	polysaccharide deacetylase
BC8716_13005	COG5002	protein histidine kinase activity
BC8716_13010	COG0745	RESPONSE REGULATOR receiver
BC8716_13015	COG2224	Isocitrate lyase
BC8716_13025	COG3711	transcriptional antiterminator
BC8716_13030	COG1263	PTS System
BC8716_13030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_13030	COG2190	(PTS) system
BC8716_13035	COG2723	6-phospho-beta-galactosidase activity
BC8716_13040	COG2723	6-phospho-beta-galactosidase activity
BC8716_13045	COG2226	methyltransferase
BC8716_13050	COG0667	Aldo Keto reductase
BC8716_13055	COG2207	Transcriptional regulator
BC8716_13055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC8716_13060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC8716_13065	COG2814	Major facilitator Superfamily
BC8716_13070	COG0583	DNA-binding transcription factor activity
BC8716_13135	COG1801	Protein of unknown function DUF72
BC8716_13140	COG0730	response to heat
BC8716_13145	COG0737	Belongs to the 5'-nucleotidase family
BC8716_13150	COG3377	Domain of unknown function (DUF1805)
BC8716_13155	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BC8716_13170	COG1757	Na H antiporter
BC8716_13175	COG0739	heme binding
BC8716_13180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BC8716_13190	COG4470	Protein conserved in bacteria
BC8716_13200	COG2445	Protein of unknown function DUF86
BC8716_13205	COG0647	UMP catabolic process
BC8716_13210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC8716_13215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BC8716_13220	COG0460	homoserine dehydrogenase
BC8716_13225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BC8716_13230	COG0083	homoserine kinase activity
BC8716_13235	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BC8716_13240	COG4837	Protein of unknown function (DUF1462)
BC8716_13245	COG1252	NADH dehydrogenase
BC8716_13250	COG4844	belongs to the
BC8716_13260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BC8716_13265	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BC8716_13275	COG0316	Belongs to the HesB IscA family
BC8716_13280	COG0765	amino acid transport
BC8716_13285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC8716_13295	COG3711	transcriptional antiterminator
BC8716_13300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_13305	COG0246	Mannitol dehydrogenase
BC8716_13310	COG0492	ferredoxin-NADP+ reductase activity
BC8716_13315	COG1252	NADH dehydrogenase
BC8716_13325	COG3584	3D domain protein
BC8716_13330	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BC8716_13345	COG2056	Na+-H+ antiporter family
BC8716_13350	COG0776	regulation of translation
BC8716_13355	COG1295	ribonuclease BN
BC8716_13360	COG1854	S-ribosylhomocysteine lyase activity
BC8716_13365	COG1943	Transposase
BC8716_13370	COG1522	sequence-specific DNA binding
BC8716_13375	COG0436	Aminotransferase
BC8716_13380	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BC8716_13390	COG1098	S1 RNA binding domain
BC8716_13395	COG2155	Conserved Protein
BC8716_13400	COG1979	alcohol dehydrogenase
BC8716_13405	COG1181	Belongs to the D-alanine--D-alanine ligase family
BC8716_13410	COG0166	Belongs to the GPI family
BC8716_13430	COG1227	inorganic diphosphatase activity
BC8716_13435	COG0109	protoheme IX farnesyltransferase activity
BC8716_13440	COG4846	Membrane protein involved in cytochrome C biogenesis
BC8716_13460	COG1823	symporter activity
BC8716_13465	COG0671	phosphoesterase, PA-phosphatase related
BC8716_13470	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC8716_13475	COG4605	iron ion homeostasis
BC8716_13480	COG4604	ABC transporter, ATP-binding protein
BC8716_13495	COG1428	Deoxynucleoside kinase
BC8716_13500	COG1428	Deoxynucleoside kinase
BC8716_13505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BC8716_13515	COG2814	Major facilitator Superfamily
BC8716_13520	COG0494	nUDIX hydrolase
BC8716_13525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC8716_13530	COG1116	anion transmembrane transporter activity
BC8716_13535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC8716_13540	COG1506	peptidase
BC8716_13550	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BC8716_13555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BC8716_13560	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BC8716_13565	COG2267	carboxylic ester hydrolase activity
BC8716_13570	COG0288	reversible hydration of carbon dioxide
BC8716_13575	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BC8716_13580	COG2814	Major facilitator Superfamily
BC8716_13585	COG0039	L-malate dehydrogenase activity
BC8716_13590	COG0495	leucyl-tRNA aminoacylation
BC8716_13595	COG1943	Transposase
BC8716_13620	COG2081	HI0933 family
BC8716_13625	COG1473	amidohydrolase
BC8716_13630	COG0432	Pfam Uncharacterised protein family UPF0047
BC8716_13635	COG3386	PFAM SMP-30 Gluconolaconase
BC8716_13640	COG2244	polysaccharide biosynthetic process
BC8716_13645	COG0772	Belongs to the SEDS family
BC8716_13650	COG0772	Belongs to the SEDS family
BC8716_13655	COG1187	pseudouridine synthase activity
BC8716_13660	COG1349	DNA-binding transcription factor activity
BC8716_13665	COG0346	lactoylglutathione lyase activity
BC8716_13680	COG3708	Transcriptional regulator
BC8716_13680	COG2207	Transcriptional regulator
BC8716_13685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC8716_13700	COG1346	cytolysis
BC8716_13715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC8716_13720	COG0022	dehydrogenase e1 component
BC8716_13725	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC8716_13740	COG0788	formyltetrahydrofolate deformylase activity
BC8716_13745	COG0510	thiamine kinase activity
BC8716_13755	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BC8716_13765	COG1363	Peptidase, m42
BC8716_13770	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BC8716_13785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC8716_13790	COG4848	Belongs to the UPF0354 family
BC8716_13795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC8716_13800	COG1674	ftsk spoiiie
BC8716_13805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BC8716_13810	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BC8716_13815	COG4980	gas vesicle protein
BC8716_13820	COG1605	Chorismate mutase
BC8716_13820	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC8716_13830	COG0123	including yeast histone deacetylase and acetoin utilization protein
BC8716_13835	COG0517	IMP dehydrogenase activity
BC8716_13840	COG0454	-acetyltransferase
BC8716_13845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC8716_13850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC8716_13855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BC8716_13860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BC8716_13865	COG1956	GAF domain-containing protein
BC8716_13875	COG1309	transcriptional regulator
BC8716_13880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC8716_13885	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BC8716_13890	COG1104	cysteine desulfurase activity
BC8716_13895	COG0301	tRNA thio-modification
BC8716_13905	COG0616	signal peptide processing
BC8716_13910	COG1714	RDD family
BC8716_13920	COG3874	Sporulation protein YtfJ
BC8716_13925	COG2814	Major facilitator Superfamily
BC8716_13930	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BC8716_13935	COG0827	DNA restriction-modification system
BC8716_13940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BC8716_13945	COG3481	metal-dependent phosphohydrolase, HD sub domain
BC8716_13955	COG0137	argininosuccinate synthase activity
BC8716_13960	COG0165	Argininosuccinate lyase
BC8716_13965	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_13975	COG0006	proline dipeptidase activity
BC8716_13980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BC8716_13990	COG4109	DRTGG domain
BC8716_14000	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BC8716_14015	COG0587	DNA-directed DNA polymerase activity
BC8716_14020	COG0281	malic enzyme
BC8716_14025	COG2186	Transcriptional regulator
BC8716_14030	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BC8716_14035	COG0825	malonyl-CoA metabolic process
BC8716_14040	COG0205	6-phosphofructokinase activity
BC8716_14050	COG3030	protein affecting phage T7 exclusion by the F plasmid
BC8716_14055	COG2707	UPF0756 membrane protein
BC8716_14060	COG0372	Belongs to the citrate synthase family
BC8716_14065	COG0538	isocitrate dehydrogenase activity
BC8716_14070	COG0039	L-malate dehydrogenase activity
BC8716_14075	COG1522	sequence-specific DNA binding
BC8716_14080	COG0745	RESPONSE REGULATOR receiver
BC8716_14085	COG5002	protein histidine kinase activity
BC8716_14090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC8716_14090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC8716_14095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BC8716_14100	COG1971	Probably functions as a manganese efflux pump
BC8716_14105	COG0237	dephospho-CoA kinase activity
BC8716_14110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC8716_14115	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BC8716_14125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BC8716_14130	COG3611	Membrane attachment protein
BC8716_14135	COG1484	DNA-dependent DNA replication
BC8716_14140	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BC8716_14150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC8716_14165	COG2027	D-alanyl-D-alanine carboxypeptidase
BC8716_14180	COG1136	(ABC) transporter
BC8716_14185	COG0577	efflux transmembrane transporter activity
BC8716_14190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BC8716_14195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BC8716_14200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BC8716_14205	COG3162	membrane
BC8716_14210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC8716_14220	COG1363	Peptidase, m42
BC8716_14240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC8716_14245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BC8716_14250	COG0072	phenylalanine-tRNA ligase activity
BC8716_14255	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BC8716_14260	COG1286	toxin biosynthetic process
BC8716_14265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC8716_14265	COG1796	DNA polymerase
BC8716_14270	COG1193	negative regulation of DNA recombination
BC8716_14275	COG3766	membrane
BC8716_14280	COG0318	PFAM AMP-dependent synthetase and ligase
BC8716_14285	COG1309	transcriptional regulator
BC8716_14290	COG1024	Enoyl-CoA hydratase
BC8716_14295	COG2086	electron transfer activity
BC8716_14300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BC8716_14305	COG3118	belongs to the thioredoxin family
BC8716_14310	COG0322	excinuclease ABC activity
BC8716_14320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC8716_14325	COG2009	succinate dehydrogenase
BC8716_14330	COG1053	succinate dehydrogenase
BC8716_14335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BC8716_14340	COG0824	Thioesterase
BC8716_14345	COG2197	response regulator
BC8716_14355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_14360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BC8716_14365	COG1846	Transcriptional regulator
BC8716_14370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BC8716_14385	COG5401	PFAM Sporulation and spore germination
BC8716_14390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BC8716_14395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BC8716_14400	COG0622	Phosphoesterase
BC8716_14420	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BC8716_14435	COG2826	transposase and inactivated derivatives, IS30 family
BC8716_14440	COG2132	Multicopper oxidase
BC8716_14455	COG0129	dihydroxy-acid dehydratase activity
BC8716_14460	COG0028	Belongs to the TPP enzyme family
BC8716_14465	COG0440	acetolactate synthase activity
BC8716_14470	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BC8716_14475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC8716_14480	COG0473	3-isopropylmalate dehydrogenase activity
BC8716_14485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BC8716_14490	COG0066	3-isopropylmalate dehydratase activity
BC8716_14495	COG0457	Tetratricopeptide repeat
BC8716_14495	COG1477	protein flavinylation
BC8716_14500	COG0544	peptidyl-prolyl cis-trans isomerase activity
BC8716_14505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BC8716_14510	COG1067	ATP-dependent peptidase activity
BC8716_14510	COG0470	DNA polymerase III
BC8716_14515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BC8716_14520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BC8716_14525	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BC8716_14530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC8716_14535	COG0181	hydroxymethylbilane synthase activity
BC8716_14545	COG0113	porphobilinogen synthase activity
BC8716_14550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BC8716_14555	COG1388	LysM domain
BC8716_14555	COG1388	LysM domain
BC8716_14580	COG0525	valine-tRNA ligase activity
BC8716_14585	COG0285	dihydrofolate synthase activity
BC8716_14590	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BC8716_14600	COG0823	Involved in the tonB-independent uptake of proteins
BC8716_14600	COG4946	Tricorn protease homolog
BC8716_14600	COG1506	peptidase
BC8716_14605	COG0424	maF-like protein
BC8716_14610	COG2003	Belongs to the UPF0758 family
BC8716_14615	COG1077	Cell shape determining protein MreB Mrl
BC8716_14620	COG1792	Involved in formation and maintenance of cell shape
BC8716_14625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BC8716_14630	COG0850	regulation of cytokinetic process
BC8716_14635	COG2894	cell division
BC8716_14640	COG0693	protein deglycase activity
BC8716_14645	COG0315	cyclic pyranopterin monophosphate synthase activity
BC8716_14650	COG1268	BioY protein
BC8716_14655	COG0667	Aldo Keto reductase
BC8716_14660	COG0739	heme binding
BC8716_14665	COG1994	Peptidase M50
BC8716_14670	COG1530	ribonuclease E activity
BC8716_14675	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BC8716_14680	COG2868	ribosomal protein
BC8716_14685	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BC8716_14690	COG2002	toxin-antitoxin pair type II binding
BC8716_14695	COG1228	amidohydrolase
BC8716_14700	COG1573	uracil-dna glycosylase
BC8716_14705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC8716_14710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BC8716_14720	COG2318	DinB family
BC8716_14725	COG1943	Transposase
BC8716_14730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC8716_14735	COG0573	inorganic phosphate transmembrane transporter activity
BC8716_14740	COG0581	inorganic phosphate transmembrane transporter activity
BC8716_14745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BC8716_14750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BC8716_14765	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BC8716_14775	COG2198	Histidine kinase
BC8716_14775	COG0643	Histidine kinase
BC8716_14780	COG0835	chemotaxis
BC8716_14785	COG0367	asparagine synthase
BC8716_14795	COG1834	amidinotransferase
BC8716_14800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC8716_14810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC8716_14810	COG0425	Belongs to the sulfur carrier protein TusA family
BC8716_14820	COG1073	alpha beta
BC8716_14825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC8716_14835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC8716_14855	COG0561	phosphatase activity
BC8716_14860	COG3336	cytochrome c oxidase
BC8716_14865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BC8716_14870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BC8716_14875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BC8716_14880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC8716_14885	COG0505	Belongs to the CarA family
BC8716_14890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BC8716_14895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BC8716_14900	COG2267	carboxylic ester hydrolase activity
BC8716_14910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BC8716_14925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC8716_14930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC8716_14935	COG0617	tRNA 3'-terminal CCA addition
BC8716_14945	COG3773	Cell wall hydrolase
BC8716_14945	COG3409	Peptidoglycan-binding domain 1 protein
BC8716_14950	COG2340	Cysteine-rich secretory protein family
BC8716_14955	COG1072	(Pantothenic acid kinase))
BC8716_14960	COG2357	RelA SpoT domain protein
BC8716_14965	COG5504	Zn-dependent protease
BC8716_14975	COG0180	Tryptophanyl-tRNA synthetase
BC8716_14985	COG1418	mRNA catabolic process
BC8716_14990	COG1272	protein, Hemolysin III
BC8716_15005	COG0456	acetyltransferase
BC8716_15010	COG1393	Belongs to the ArsC family
BC8716_15035	COG2346	COG2346, Truncated hemoglobins
BC8716_15040	COG0741	lytic transglycosylase activity
BC8716_15055	COG2357	RelA SpoT domain protein
BC8716_15060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BC8716_15065	COG0564	pseudouridine synthase activity
BC8716_15080	COG2226	methyltransferase
BC8716_15110	COG0210	DNA helicase
BC8716_15115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BC8716_15170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BC8716_15175	COG4537	Required for transformation and DNA binding
BC8716_15210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC8716_15225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC8716_15230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BC8716_15235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC8716_15240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC8716_15245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC8716_15250	COG0095	Lipoate-protein ligase
BC8716_15255	COG3973	AAA domain
BC8716_15265	COG1533	DNA photolyase activity
BC8716_15270	COG1321	iron dependent repressor
BC8716_15275	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC8716_15290	COG0006	proline dipeptidase activity
BC8716_15295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BC8716_15300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BC8716_15315	COG3854	ATPases associated with a variety of cellular activities
BC8716_15360	COG0511	ligase activity, forming carbon-carbon bonds
BC8716_15365	COG0439	Biotin carboxylase
BC8716_15370	COG1302	Protein conserved in bacteria
BC8716_15375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC8716_15380	COG1570	exodeoxyribonuclease VII activity
BC8716_15385	COG1722	exodeoxyribonuclease VII activity
BC8716_15390	COG0142	geranyltranstransferase activity
BC8716_15395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BC8716_15400	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BC8716_15405	COG1438	arginine binding
BC8716_15415	COG0750	zinc metalloprotease
BC8716_15420	COG0745	RESPONSE REGULATOR receiver
BC8716_15435	COG3290	protein histidine kinase activity
BC8716_15435	COG3829	transcription factor binding
BC8716_15445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC8716_15450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC8716_15455	COG0022	dehydrogenase e1 component
BC8716_15460	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC8716_15570	COG5280	Phage tail tape measure protein TP901
BC8716_15570	COG3953	SLT domain
BC8716_15580	COG5434	Belongs to the glycosyl hydrolase 28 family
BC8716_15610	COG4824	toxin secretion phage lysis holin
BC8716_15625	COG1793	dna ligase
BC8716_15670	COG3646	Phage regulatory protein
BC8716_15670	COG3645	SOS response
BC8716_15725	COG2226	methyltransferase
BC8716_15760	COG0561	phosphatase activity
BC8716_15770	COG1937	Protein conserved in bacteria
BC8716_15775	COG2608	mercury ion transmembrane transporter activity
BC8716_15790	COG1902	pentaerythritol trinitrate reductase activity
BC8716_15800	COG0702	epimerase
BC8716_15820	COG0668	transmembrane transport
BC8716_15835	COG2171	N-acyltransferase activity
BC8716_15840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC8716_15845	COG1473	amidohydrolase
BC8716_15855	COG0668	transmembrane transport
BC8716_15860	COG0450	alkyl hydroperoxide reductase
BC8716_15865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC8716_15870	COG0569	domain protein
BC8716_15875	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC8716_15885	COG0242	peptide deformylase activity
BC8716_15905	COG0022	dehydrogenase e1 component
BC8716_15910	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC8716_15920	COG3344	reverse transcriptase
BC8716_15925	COG0444	Belongs to the ABC transporter superfamily
BC8716_15930	COG4608	Belongs to the ABC transporter superfamily
BC8716_15940	COG0601	transmembrane transport
BC8716_15945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC8716_15955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC8716_15975	COG1982	Orn Lys Arg decarboxylase major
BC8716_15985	COG4493	Belongs to the UPF0637 family
BC8716_15990	COG0483	inositol monophosphate 1-phosphatase activity
BC8716_16015	COG4896	Protein conserved in bacteria
BC8716_16020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BC8716_16025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC8716_16030	COG4838	Belongs to the UPF0358 family
BC8716_16035	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BC8716_16040	COG1612	heme a metabolic process
BC8716_16080	COG2340	Cysteine-rich secretory protein family
BC8716_16105	COG3679	Belongs to the UPF0342 family
BC8716_16110	COG4471	UPF0298 protein
BC8716_16120	COG0742	ribosomal rna small subunit methyltransferase
BC8716_16125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BC8716_16130	COG3314	Sporulation integral membrane protein YlbJ
BC8716_16135	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC8716_16140	COG3480	Lon protease (S16) C-terminal proteolytic domain
BC8716_16145	COG1323	Belongs to the UPF0348 family
BC8716_16150	COG1399	metal-binding, possibly nucleic acid-binding protein
BC8716_16155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BC8716_16165	COG0454	-acetyltransferase
BC8716_16170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC8716_16180	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BC8716_16185	COG2001	Belongs to the MraZ family
BC8716_16190	COG0275	rRNA processing
BC8716_16195	COG4839	cell division protein FtsL
BC8716_16205	COG0768	penicillin binding
BC8716_16210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BC8716_16215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BC8716_16220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC8716_16225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BC8716_16230	COG0772	Belongs to the SEDS family
BC8716_16235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BC8716_16240	COG0849	cell division
BC8716_16245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BC8716_16255	COG1191	sigma factor activity
BC8716_16260	COG1191	sigma factor activity
BC8716_16265	COG1873	PFAM PRC-barrel domain
BC8716_16275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BC8716_16280	COG1799	cell septum assembly
BC8716_16285	COG0762	integral membrane protein
BC8716_16290	COG2302	S4 RNA-binding domain
BC8716_16295	COG3599	regulation of cell shape
BC8716_16300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BC8716_16305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BC8716_16310	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BC8716_16315	COG0564	pseudouridine synthase activity
BC8716_16320	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BC8716_16325	COG2233	PERMEase
BC8716_16330	COG0540	Belongs to the ATCase OTCase family
BC8716_16335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC8716_16340	COG0505	Belongs to the CarA family
BC8716_16345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BC8716_16350	COG0543	2 iron, 2 sulfur cluster binding
BC8716_16355	COG0167	dihydroorotate dehydrogenase activity
BC8716_16360	COG0284	orotidine-5'-phosphate decarboxylase activity
BC8716_16365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BC8716_16370	COG2226	methyltransferase
BC8716_16380	COG4485	Bacterial membrane protein, YfhO
BC8716_16390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BC8716_16395	COG2052	Domain of unknown function (DUF370)
BC8716_16400	COG0194	GDP metabolic process
BC8716_16405	COG1758	RNA polymerase activity
BC8716_16410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC8716_16415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BC8716_16420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC8716_16425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC8716_16425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BC8716_16430	COG0631	protein serine/threonine phosphatase activity
BC8716_16435	COG2815	serine threonine protein kinase
BC8716_16435	COG0515	serine threonine protein kinase
BC8716_16440	COG1162	GTPase activity
BC8716_16445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC8716_16455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BC8716_16460	COG1302	Protein conserved in bacteria
BC8716_16465	COG1461	Dihydroxyacetone kinase
BC8716_16470	COG1307	EDD domain protein, DegV family
BC8716_16475	COG1760	l-serine dehydratase
BC8716_16480	COG1760	l-serine dehydratase
BC8716_16485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BC8716_16490	COG1349	DNA-binding transcription factor activity
BC8716_16495	COG0416	fatty acid biosynthetic process
BC8716_16500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BC8716_16505	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_16510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC8716_16515	COG0571	ribonuclease III activity
BC8716_16525	COG1196	nuclear chromosome segregation
BC8716_16530	COG0552	protein localization to endoplasmic reticulum
BC8716_16535	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BC8716_16540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BC8716_16545	COG0228	four-way junction DNA binding
BC8716_16550	COG1837	Belongs to the UPF0109 family
BC8716_16560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BC8716_16565	COG0336	Belongs to the RNA methyltransferase TrmD family
BC8716_16570	COG0018	arginyl-trna synthetase
BC8716_16575	COG0335	large ribosomal subunit rRNA binding
BC8716_16585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC8716_16615	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_16620	COG3836	Belongs to the HpcH HpaI aldolase family
BC8716_16655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BC8716_16675	COG0045	succinate-CoA ligase (ADP-forming) activity
BC8716_16680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BC8716_16685	COG0758	DNA mediated transformation
BC8716_16690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC8716_16695	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BC8716_16700	COG4974	Belongs to the 'phage' integrase family
BC8716_16705	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BC8716_16710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BC8716_16715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BC8716_16720	COG1815	bacterial-type flagellum-dependent cell motility
BC8716_16725	COG1558	bacterial-type flagellum-dependent cell motility
BC8716_16730	COG1677	Flagellar hook-basal body complex protein FliE
BC8716_16735	COG1766	The M ring may be actively involved in energy transduction
BC8716_16740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC8716_16745	COG1317	bacterial-type flagellum organization
BC8716_16750	COG1157	protein secretion by the type III secretion system
BC8716_16770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BC8716_16775	COG4786	Flagellar basal body rod
BC8716_16790	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC8716_16795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC8716_16795	COG1776	CheC inhibitor of MCP methylation
BC8716_16800	COG2201	protein-glutamate methylesterase activity
BC8716_16805	COG3190	flagellar
BC8716_16810	COG1338	Plays a role in the flagellum-specific transport system
BC8716_16815	COG1987	bacterial-type flagellum assembly
BC8716_16820	COG1684	flagellar biosynthetic protein fliR
BC8716_16825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC8716_16830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC8716_16835	COG1419	protein localization to endoplasmic reticulum
BC8716_16845	COG2201	protein-glutamate methylesterase activity
BC8716_16855	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BC8716_16860	COG1191	sigma factor activity
BC8716_16870	COG0052	Belongs to the universal ribosomal protein uS2 family
BC8716_16875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BC8716_16880	COG0528	UMP kinase activity
BC8716_16885	COG0233	cytoplasmic translational termination
BC8716_16890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BC8716_16895	COG4589	Belongs to the CDS family
BC8716_16900	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BC8716_16905	COG0750	zinc metalloprotease
BC8716_16910	COG0442	prolyl-tRNA aminoacylation
BC8716_16915	COG2176	DNA-directed DNA polymerase activity
BC8716_16920	COG0779	Required for maturation of 30S ribosomal subunits
BC8716_16925	COG0195	Participates in both transcription termination and antitermination
BC8716_16930	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BC8716_16935	COG1358	cellular component organization or biogenesis
BC8716_16940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BC8716_16950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BC8716_16955	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BC8716_16960	COG0196	riboflavin kinase activity
BC8716_16965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BC8716_16970	COG1185	polyribonucleotide nucleotidyltransferase activity
BC8716_16975	COG0726	polysaccharide deacetylase
BC8716_16980	COG0612	Peptidase, M16
BC8716_16990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC8716_16995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC8716_17000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BC8716_17005	COG0527	aspartate kinase activity
BC8716_17010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC8716_17015	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC8716_17020	COG0740	serine-type endopeptidase activity
BC8716_17030	COG1674	ftsk spoiiie
BC8716_17035	COG2188	Transcriptional regulator
BC8716_17040	COG0612	Peptidase, M16
BC8716_17045	COG0612	Peptidase, M16
BC8716_17050	COG0300	oxidoreductase activity
BC8716_17065	COG1426	Protein conserved in bacteria
BC8716_17070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BC8716_17075	COG1546	Belongs to the CinA family
BC8716_17075	COG1058	Belongs to the CinA family
BC8716_17080	COG0513	Belongs to the DEAD box helicase family
BC8716_17085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BC8716_17095	COG0497	DNA recombination
BC8716_17110	COG1418	mRNA catabolic process
BC8716_17115	COG1692	metallophosphoesterase
BC8716_17120	COG2359	stage V sporulation protein S
BC8716_17130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC8716_17135	COG4550	Control of competence regulator ComK, YlbF/YmcA
BC8716_17145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BC8716_17150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BC8716_17160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BC8716_17165	COG1923	regulation of RNA biosynthetic process
BC8716_17175	COG0464	growth
BC8716_17180	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BC8716_17185	COG0174	glutamine synthetase
BC8716_17190	COG0277	FAD linked oxidase domain protein
BC8716_17195	COG0247	lactate metabolic process
BC8716_17200	COG0277	FAD linked oxidase domain protein
BC8716_17205	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BC8716_17210	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC8716_17215	COG1414	Transcriptional regulator
BC8716_17230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BC8716_17235	COG2814	Major facilitator Superfamily
BC8716_17240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BC8716_17245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC8716_17250	COG4224	UPF0291 protein
BC8716_17255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BC8716_17265	COG3763	UPF0154 protein
BC8716_17270	COG1132	(ABC) transporter
BC8716_17275	COG1132	(ABC) transporter
BC8716_17300	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BC8716_17320	COG0464	growth
BC8716_17325	COG0824	Thioesterase
BC8716_17330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BC8716_17350	COG2200	EAL domain
BC8716_17375	COG0784	Response regulator, receiver
BC8716_17375	COG0835	chemotaxis
BC8716_17385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC8716_17405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC8716_17415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BC8716_17425	COG1254	Belongs to the acylphosphatase family
BC8716_17430	COG1115	amino acid carrier protein
BC8716_17435	COG2309	aminopeptidase activity
BC8716_17440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BC8716_17445	COG0720	synthase
BC8716_17450	COG0602	queuosine metabolic process
BC8716_17455	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BC8716_17465	COG4585	Histidine kinase
BC8716_17480	COG1131	(ABC) transporter
BC8716_17490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC8716_17490	COG0551	DNA topoisomerase type I activity
BC8716_17495	COG1764	response to oxidative stress
BC8716_17515	COG0567	Dehydrogenase, E1 component
BC8716_17520	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC8716_17535	COG0488	(ABC) transporter
BC8716_17540	COG0656	L-ascorbic acid biosynthetic process
BC8716_17545	COG0514	ATP-dependent DNA helicase (RecQ)
BC8716_17565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC8716_17570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC8716_17575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC8716_17580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC8716_17585	COG4876	unkown
BC8716_17590	COG1960	acyl-CoA dehydrogenase activity
BC8716_17595	COG3069	C4-dicarboxylate transmembrane transporter activity
BC8716_17615	COG1595	DNA-templated transcription, initiation
BC8716_17665	COG0561	phosphatase activity
BC8716_17670	COG1263	PTS System
BC8716_17670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_17675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BC8716_17710	COG1263	PTS System
BC8716_17710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_17715	COG3394	polysaccharide catabolic process
BC8716_17720	COG1486	melibiose metabolic process
BC8716_17725	COG2188	Transcriptional regulator
BC8716_17735	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC8716_17760	COG0438	transferase activity, transferring glycosyl groups
BC8716_17775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BC8716_17780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BC8716_17785	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BC8716_17795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BC8716_17795	COG1199	ATP-dependent helicase activity
BC8716_17800	COG0402	S-adenosylhomocysteine deaminase activity
BC8716_17820	COG0017	Asparaginyl-tRNA synthetase
BC8716_17825	COG3935	DnaD domain protein
BC8716_17830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BC8716_17835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC8716_17840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC8716_17840	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC8716_17845	COG3331	DNA recombination
BC8716_17855	COG0789	Transcriptional regulator
BC8716_17870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC8716_17875	COG0693	protein deglycase activity
BC8716_17880	COG1234	tRNA 3'-trailer cleavage
BC8716_17905	COG1413	lyase activity
BC8716_17915	COG3402	PFAM membrane-flanked domain
BC8716_17920	COG3428	Bacterial PH domain
BC8716_17945	COG0070	glutamate synthase
BC8716_17945	COG0069	glutamate synthase activity
BC8716_17945	COG0067	glutamate synthase
BC8716_17950	COG0493	'glutamate synthase
BC8716_17990	COG0561	phosphatase activity
BC8716_18000	COG0346	lactoylglutathione lyase activity
BC8716_18005	COG0400	carboxylic ester hydrolase activity
BC8716_18020	COG0814	amino acid
BC8716_18025	COG0697	spore germination
BC8716_18035	COG1205	dead DEAH box helicase
BC8716_18035	COG1111	helicase
BC8716_18040	COG3359	exonuclease
BC8716_18050	COG4474	Belongs to the UPF0398 family
BC8716_18055	COG3599	regulation of cell shape
BC8716_18060	COG0328	RNA-DNA hybrid ribonuclease activity
BC8716_18075	COG0116	Belongs to the methyltransferase superfamily
BC8716_18080	COG0673	inositol 2-dehydrogenase activity
BC8716_18085	COG3960	tartronate-semialdehyde synthase activity
BC8716_18090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC8716_18100	COG0840	transmembrane signaling receptor activity
BC8716_18100	COG3290	protein histidine kinase activity
BC8716_18140	COG1070	Carbohydrate kinase
BC8716_18170	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BC8716_18180	COG1396	sequence-specific DNA binding
BC8716_18190	COG2364	Membrane
BC8716_18200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC8716_18215	COG2723	6-phospho-beta-galactosidase activity
BC8716_18220	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_18225	COG0517	IMP dehydrogenase activity
BC8716_18225	COG1125	glycine betaine transport
BC8716_18235	COG1832	CoA-binding protein
BC8716_18240	COG0187	DNA topoisomerase II activity
BC8716_18245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC8716_18255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BC8716_18260	COG0628	permease
BC8716_18265	COG1360	Flagellar Motor Protein
BC8716_18270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BC8716_18275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC8716_18290	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BC8716_18295	COG1413	lyase activity
BC8716_18310	COG0596	Alpha beta hydrolase
BC8716_18335	COG0778	Nitroreductase
BC8716_18340	COG0778	Nitroreductase
BC8716_18360	COG1595	DNA-templated transcription, initiation
BC8716_18370	COG1131	(ABC) transporter
BC8716_18390	COG3708	Transcriptional regulator
BC8716_18390	COG2207	Transcriptional regulator
BC8716_18410	COG2814	Major facilitator Superfamily
BC8716_18435	COG0733	neurotransmitter:sodium symporter activity
BC8716_18445	COG2151	metal-sulfur cluster biosynthetic enzyme
BC8716_18455	COG0697	spore germination
BC8716_18460	COG0217	transcriptional regulatory protein
BC8716_18465	COG0708	Exodeoxyribonuclease III
BC8716_18470	COG3048	D-serine ammonia-lyase activity
BC8716_18475	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BC8716_18480	COG1082	Xylose isomerase domain protein TIM barrel
BC8716_18490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC8716_18495	COG0318	PFAM AMP-dependent synthetase and ligase
BC8716_18510	COG2329	Antibiotic biosynthesis monooxygenase
BC8716_18515	COG0626	cystathionine gamma-synthase activity
BC8716_18520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC8716_18525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_18535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC8716_18540	COG1309	transcriptional regulator
BC8716_18550	COG0791	NLP P60 protein
BC8716_18550	COG1388	LysM domain
BC8716_18555	COG2801	Transposase and inactivated derivatives
BC8716_18570	COG2094	Belongs to the DNA glycosylase MPG family
BC8716_18575	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BC8716_18580	COG1122	ATPase activity
BC8716_18595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC8716_18600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC8716_18605	COG1388	LysM domain
BC8716_18605	COG3584	3D domain protein
BC8716_18610	COG3584	3D domain protein
BC8716_18610	COG1388	LysM domain
BC8716_18615	COG2226	methyltransferase
BC8716_18620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BC8716_18630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC8716_18645	COG2153	protein acetylation
BC8716_18655	COG1690	Belongs to the RtcB family
BC8716_18665	COG1803	Methylglyoxal synthase
BC8716_18670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BC8716_18675	COG1694	Mazg nucleotide pyrophosphohydrolase
BC8716_18680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC8716_18685	COG2814	Major facilitator Superfamily
BC8716_18690	COG2738	Putative neutral zinc metallopeptidase
BC8716_18700	COG4347	Protein of unknown function (DUF1405)
BC8716_18710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC8716_18715	COG0723	plastoquinol--plastocyanin reductase activity
BC8716_18725	COG5582	Belongs to the UPF0302 family
BC8716_18730	COG0457	Tetratricopeptide repeat
BC8716_18735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BC8716_18740	COG0287	Prephenate dehydrogenase
BC8716_18745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC8716_18750	COG0159	tryptophan synthase activity
BC8716_18755	COG0133	tryptophan synthase activity
BC8716_18760	COG0135	phosphoribosylanthranilate isomerase activity
BC8716_18765	COG0134	indole-3-glycerol-phosphate synthase activity
BC8716_18770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC8716_18780	COG4401	Chorismate mutase type I
BC8716_18785	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BC8716_18790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BC8716_18795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BC8716_18800	COG0105	UTP biosynthetic process
BC8716_18805	COG0142	geranyltranstransferase activity
BC8716_18815	COG0109	protoheme IX farnesyltransferase activity
BC8716_18820	COG2226	methyltransferase
BC8716_18825	COG0142	geranyltranstransferase activity
BC8716_18835	COG0302	gtp cyclohydrolase
BC8716_18840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC8716_18860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BC8716_18865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BC8716_18870	COG1160	GTP binding
BC8716_18880	COG0539	negative regulation of cytoplasmic translation
BC8716_18885	COG0204	Acyl-transferase
BC8716_18890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BC8716_18895	COG2959	enzyme of heme biosynthesis
BC8716_18900	COG3409	Peptidoglycan-binding domain 1 protein
BC8716_18900	COG3773	Cell wall hydrolase
BC8716_18905	COG1410	methionine synthase
BC8716_18905	COG0646	methionine synthase
BC8716_18910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BC8716_18910	COG0646	methionine synthase
BC8716_18915	COG0626	cystathionine gamma-synthase activity
BC8716_18920	COG2339	peptidase activity
BC8716_18930	COG0492	ferredoxin-NADP+ reductase activity
BC8716_18935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC8716_18945	COG5002	protein histidine kinase activity
BC8716_18950	COG0745	RESPONSE REGULATOR receiver
BC8716_18955	COG4862	establishment of competence for transformation
BC8716_18960	COG0789	Transcriptional regulator
BC8716_18965	COG1408	metallophosphoesterase
BC8716_18970	COG1943	Transposase
BC8716_18975	COG1473	amidohydrolase
BC8716_18985	COG0438	transferase activity, transferring glycosyl groups
BC8716_18990	COG0438	transferase activity, transferring glycosyl groups
BC8716_19020	COG1266	CAAX protease self-immunity
BC8716_19025	COG0514	ATP-dependent DNA helicase (RecQ)
BC8716_19030	COG4955	Helix-turn-helix domain
BC8716_19040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC8716_19045	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC8716_19050	COG0861	Integral membrane protein TerC family
BC8716_19060	COG1120	ATPase activity
BC8716_19065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC8716_19070	COG5002	protein histidine kinase activity
BC8716_19075	COG0745	RESPONSE REGULATOR receiver
BC8716_19080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC8716_19085	COG1333	cytochrome c biogenesis protein
BC8716_19090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC8716_19095	COG1187	pseudouridine synthase activity
BC8716_19100	COG0700	Nucleoside recognition
BC8716_19105	COG2715	membrane protein required for spore maturation
BC8716_19110	COG1686	Belongs to the peptidase S11 family
BC8716_19120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC8716_19135	COG2323	membrane
BC8716_19150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC8716_19155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BC8716_19160	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_19170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BC8716_19175	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BC8716_19180	COG1547	Domain of unknown function (DUF309)
BC8716_19185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BC8716_19190	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC8716_19190	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC8716_19200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BC8716_19205	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_19210	COG2084	Dehydrogenase
BC8716_19215	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BC8716_19220	COG2079	MmgE PrpD family protein
BC8716_19225	COG0372	Belongs to the citrate synthase family
BC8716_19245	COG0583	DNA-binding transcription factor activity
BC8716_19250	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BC8716_19255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BC8716_19260	COG0019	diaminopimelate decarboxylase activity
BC8716_19265	COG0697	spore germination
BC8716_19280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC8716_19290	COG1943	Transposase
BC8716_19300	COG2172	sigma factor antagonist activity
BC8716_19310	COG1686	Belongs to the peptidase S11 family
BC8716_19315	COG0726	polysaccharide deacetylase
BC8716_19320	COG1988	membrane-bound metal-dependent
BC8716_19335	COG2814	Major facilitator Superfamily
BC8716_19345	COG1764	response to oxidative stress
BC8716_19355	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BC8716_19360	COG4974	Belongs to the 'phage' integrase family
BC8716_19370	COG0735	belongs to the Fur family
BC8716_19375	COG1300	Membrane
BC8716_19380	COG0494	nUDIX hydrolase
BC8716_19390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC8716_19395	COG1968	undecaprenyl-diphosphatase activity
BC8716_19400	COG1943	Transposase
BC8716_19405	COG0395	ABC-type sugar transport system, permease component
BC8716_19410	COG1175	transmembrane transport
BC8716_19420	COG2972	Histidine kinase
BC8716_19430	COG1850	ribulose-bisphosphate carboxylase activity
BC8716_19435	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BC8716_19440	COG2190	(PTS) system
BC8716_19450	COG1510	regulation of RNA biosynthetic process
BC8716_19470	COG0367	asparagine synthase
BC8716_19475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BC8716_19480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BC8716_19485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC8716_19495	COG0527	aspartate kinase activity
BC8716_19505	COG0789	Transcriptional regulator
BC8716_19510	COG2861	carbohydrate metabolic process
BC8716_19525	COG0517	IMP dehydrogenase activity
BC8716_19535	COG1728	Protein conserved in bacteria
BC8716_19540	COG0726	polysaccharide deacetylase
BC8716_19545	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC8716_19550	COG0346	lactoylglutathione lyase activity
BC8716_19555	COG1376	ErfK ybiS ycfS ynhG family protein
BC8716_19560	COG4129	membrane
BC8716_19565	COG4191	Histidine kinase
BC8716_19580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC8716_19585	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC8716_19590	COG0114	fumarate hydratase activity
BC8716_19600	COG1396	sequence-specific DNA binding
BC8716_19605	COG1396	sequence-specific DNA binding
BC8716_19615	COG2382	esterase
BC8716_19620	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BC8716_19625	COG2153	protein acetylation
BC8716_19630	COG0011	TIGRFAM Protein of
BC8716_19640	COG0351	phosphomethylpyrimidine kinase
BC8716_19645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC8716_19650	COG2022	thiamine diphosphate biosynthetic process
BC8716_19660	COG0352	thiamine-phosphate diphosphorylase activity
BC8716_19665	COG1027	Aspartate ammonia-lyase
BC8716_19670	COG1940	carbohydrate kinase activity
BC8716_19690	COG0697	spore germination
BC8716_19695	COG0705	Rhomboid family
BC8716_19695	COG0457	Tetratricopeptide repeat
BC8716_19710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC8716_19720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BC8716_19725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BC8716_19755	COG0477	Major facilitator Superfamily
BC8716_19760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BC8716_19790	COG0704	Plays a role in the regulation of phosphate uptake
BC8716_19805	COG4086	secreted protein
BC8716_19810	COG2814	Major facilitator Superfamily
BC8716_19820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BC8716_19825	COG4709	membrane
BC8716_19830	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BC8716_19840	COG0735	belongs to the Fur family
BC8716_19845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC8716_19850	COG1121	(ABC) transporter
BC8716_19860	COG5002	protein histidine kinase activity
BC8716_19870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BC8716_19875	COG0513	Belongs to the DEAD box helicase family
BC8716_19885	COG1329	Transcriptional regulator
BC8716_19890	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BC8716_19895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BC8716_19900	COG2384	SAM-dependent methyltransferase
BC8716_19905	COG2010	Cytochrome c
BC8716_19910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC8716_19915	COG0358	DNA primase activity
BC8716_19920	COG1671	Belongs to the UPF0178 family
BC8716_19925	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BC8716_19930	COG0517	IMP dehydrogenase activity
BC8716_19935	COG0751	glycine-tRNA ligase activity
BC8716_19940	COG0752	glycyl-tRNA synthetase alpha subunit
BC8716_19945	COG1381	Involved in DNA repair and RecF pathway recombination
BC8716_19955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BC8716_19960	COG0295	cytidine deaminase activity
BC8716_19965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BC8716_19970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BC8716_19975	COG1480	7TM receptor with intracellular HD hydrolase
BC8716_19980	COG1702	phosphate starvation-inducible protein PhoH
BC8716_20000	COG4864	UPF0365 protein
BC8716_20005	COG1030	water channel activity
BC8716_20010	COG1610	YqeY-like protein
BC8716_20015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BC8716_20020	COG1283	sodium-dependent phosphate transmembrane transporter activity
BC8716_20025	COG0667	Aldo Keto reductase
BC8716_20030	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BC8716_20035	COG1301	dicarboxylic acid transport
BC8716_20040	COG2226	methyltransferase
BC8716_20045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC8716_20050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BC8716_20055	COG2264	protein methyltransferase activity
BC8716_20060	COG0484	heat shock protein binding
BC8716_20065	COG0443	Heat shock 70 kDa protein
BC8716_20070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BC8716_20075	COG1420	regulation of RNA biosynthetic process
BC8716_20080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC8716_20085	COG0481	GTPase activity
BC8716_20095	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC8716_20100	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BC8716_20105	COG0268	Binds directly to 16S ribosomal RNA
BC8716_20110	COG1466	dna polymerase III delta subunit
BC8716_20120	COG2333	competence protein COMEC
BC8716_20120	COG0658	competence protein
BC8716_20125	COG2131	deaminase
BC8716_20130	COG1555	photosystem II stabilization
BC8716_20130	COG1596	polysaccharide export
BC8716_20135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC8716_20140	COG2226	methyltransferase
BC8716_20145	COG2996	Protein conserved in bacteria
BC8716_20150	COG0799	negative regulation of ribosome biogenesis
BC8716_20155	COG1713	HD superfamily hydrolase involved in NAD metabolism
BC8716_20160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BC8716_20165	COG1534	Rna-binding protein
BC8716_20170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BC8716_20175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BC8716_20180	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BC8716_20225	COG0776	regulation of translation
BC8716_20240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC8716_20245	COG2223	nitrite transmembrane transporter activity
BC8716_20250	COG0243	molybdopterin cofactor binding
BC8716_20255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC8716_20260	COG2146	nitrite reductase [NAD(P)H] activity
BC8716_20265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC8716_20270	COG1587	Uroporphyrinogen-III synthase
BC8716_20270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BC8716_20285	COG4536	flavin adenine dinucleotide binding
BC8716_20290	COG1191	sigma factor activity
BC8716_20295	COG0385	Bile acid
BC8716_20305	COG1288	antiporter activity
BC8716_20310	COG0095	Lipoate-protein ligase
BC8716_20315	COG0494	nUDIX hydrolase
BC8716_20320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BC8716_20325	COG0366	Alpha amylase catalytic
BC8716_20330	COG1309	transcriptional regulator
BC8716_20340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC8716_20345	COG0444	Belongs to the ABC transporter superfamily
BC8716_20350	COG4608	Belongs to the ABC transporter superfamily
BC8716_20355	COG0747	negative chemotaxis
BC8716_20370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC8716_20375	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BC8716_20380	COG1793	dna ligase
BC8716_20380	COG3285	dna ligase
BC8716_20390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BC8716_20395	COG0572	uridine kinase
BC8716_20405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BC8716_20410	COG3906	Belongs to the UPF0473 family
BC8716_20415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BC8716_20420	COG4472	Bacterial protein of unknown function (DUF965)
BC8716_20425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC8716_20430	COG0628	permease
BC8716_20445	COG3881	PFAM PRC-barrel domain
BC8716_20450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC8716_20460	COG0482	sulfurtransferase activity
BC8716_20465	COG1104	cysteine desulfurase activity
BC8716_20470	COG1959	2 iron, 2 sulfur cluster binding
BC8716_20475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BC8716_20485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BC8716_20490	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BC8716_20510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BC8716_20515	COG0124	histidyl-tRNA synthetase
BC8716_20520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC8716_20525	COG0673	inositol 2-dehydrogenase activity
BC8716_20535	COG1609	Transcriptional regulator
BC8716_20540	COG2826	transposase and inactivated derivatives, IS30 family
BC8716_20545	COG1490	D-aminoacyl-tRNA deacylase activity
BC8716_20550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC8716_20555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC8716_20560	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BC8716_20560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BC8716_20565	COG5416	Lipopolysaccharide assembly protein A domain
BC8716_20570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC8716_20570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC8716_20575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC8716_20575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC8716_20585	COG2244	polysaccharide biosynthetic process
BC8716_20605	COG1862	Preprotein translocase
BC8716_20610	COG0343	queuine tRNA-ribosyltransferase activity
BC8716_20615	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BC8716_20625	COG2255	four-way junction helicase activity
BC8716_20630	COG0632	four-way junction helicase activity
BC8716_20650	COG1388	LysM domain
BC8716_20655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BC8716_20660	COG0157	Belongs to the NadC ModD family
BC8716_20665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BC8716_20670	COG1104	cysteine desulfurase activity
BC8716_20675	COG1827	regulation of RNA biosynthetic process
BC8716_20680	COG0077	Prephenate dehydratase
BC8716_20685	COG4492	Belongs to the UPF0735 family
BC8716_20690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BC8716_20695	COG3290	protein histidine kinase activity
BC8716_20715	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BC8716_20720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC8716_20725	COG0785	Cytochrome C biogenesis protein
BC8716_20735	COG4473	ABC transporter
BC8716_20740	COG1131	(ABC) transporter
BC8716_20745	COG0537	adenosine 5'-monophosphoramidase activity
BC8716_20750	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BC8716_20760	COG1846	Transcriptional regulator
BC8716_20775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC8716_20785	COG3481	metal-dependent phosphohydrolase, HD sub domain
BC8716_20790	COG2770	Histidine kinase
BC8716_20790	COG2205	protein histidine kinase activity
BC8716_20795	COG0745	RESPONSE REGULATOR receiver
BC8716_20810	COG0561	phosphatase activity
BC8716_20815	COG3679	Belongs to the UPF0342 family
BC8716_20820	COG4399	Belongs to the UPF0754 family
BC8716_20830	COG2508	Transcriptional regulator
BC8716_20835	COG3842	ATPase activity
BC8716_20860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC8716_20865	COG1024	Enoyl-CoA hydratase
BC8716_20870	COG0511	ligase activity, forming carbon-carbon bonds
BC8716_20875	COG0439	Biotin carboxylase
BC8716_20880	COG1960	acyl-CoA dehydrogenase activity
BC8716_20885	COG1704	LemA family
BC8716_20900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC8716_20905	COG1132	(ABC) transporter
BC8716_20910	COG1132	(ABC) transporter
BC8716_20915	COG2719	SpoVR family
BC8716_20920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC8716_20925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC8716_20930	COG1489	DNA binding
BC8716_20935	COG3153	acetyltransferase
BC8716_20935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC8716_20945	COG0584	glycerophosphoryl diester phosphodiesterase
BC8716_20950	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC8716_20955	COG0436	Aminotransferase
BC8716_20960	COG0778	Nitroreductase
BC8716_20965	COG0363	glucosamine-6-phosphate deaminase activity
BC8716_20970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BC8716_20980	COG0165	Argininosuccinate lyase
BC8716_20985	COG2188	Transcriptional regulator
BC8716_20995	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_21025	COG2814	Major facilitator Superfamily
BC8716_21040	COG2718	Belongs to the UPF0229 family
BC8716_21065	COG2766	serine protein kinase
BC8716_21070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC8716_21085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BC8716_21100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC8716_21115	COG0783	Belongs to the Dps family
BC8716_21120	COG1363	Peptidase, m42
BC8716_21130	COG1131	(ABC) transporter
BC8716_21135	COG1725	Transcriptional regulator
BC8716_21145	COG1131	(ABC) transporter
BC8716_21155	COG2207	Transcriptional regulator
BC8716_21155	COG1917	Cupin 2, conserved barrel domain protein
BC8716_21160	COG1621	beta-fructofuranosidase activity
BC8716_21170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_21170	COG1263	PTS System
BC8716_21180	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_21190	COG1966	Carbon starvation protein
BC8716_21205	COG3012	SEC-C Motif Domain Protein
BC8716_21205	COG1405	negative regulation of cell septum assembly
BC8716_21225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC8716_21240	COG0584	glycerophosphoryl diester phosphodiesterase
BC8716_21250	COG4894	glucomannan catabolic process
BC8716_21255	COG1442	glycosyl transferase family 8
BC8716_21270	COG1131	(ABC) transporter
BC8716_21275	COG2197	response regulator
BC8716_21280	COG4585	Histidine kinase
BC8716_21285	COG0406	alpha-ribazole phosphatase activity
BC8716_21300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BC8716_21315	COG1733	regulation of RNA biosynthetic process
BC8716_21325	COG0789	Transcriptional regulator
BC8716_21350	COG2267	carboxylic ester hydrolase activity
BC8716_21365	COG1621	beta-fructofuranosidase activity
BC8716_21370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_21370	COG1263	PTS System
BC8716_21415	COG3964	amidohydrolase
BC8716_21445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC8716_21450	COG0789	Transcriptional regulator
BC8716_21470	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_21485	COG2814	Major facilitator Superfamily
BC8716_21490	COG0640	Transcriptional regulator
BC8716_21500	COG5434	Belongs to the glycosyl hydrolase 28 family
BC8716_21605	COG0735	belongs to the Fur family
BC8716_21615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC8716_21620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BC8716_21625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BC8716_21630	COG4129	membrane
BC8716_21635	COG1132	(ABC) transporter
BC8716_21640	COG3557	Belongs to the UPF0374 family
BC8716_21650	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_21665	COG1028	Short-chain dehydrogenase reductase Sdr
BC8716_21675	COG1988	membrane-bound metal-dependent
BC8716_21695	COG2137	regulation of response to DNA damage stimulus
BC8716_21700	COG1090	epimerase
BC8716_21710	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC8716_21715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BC8716_21740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BC8716_21755	COG0445	tRNA wobble uridine modification
BC8716_21765	COG0726	polysaccharide deacetylase
BC8716_21775	COG1253	flavin adenine dinucleotide binding
BC8716_21780	COG0588	phosphoglycerate mutase activity
BC8716_21785	COG0535	radical SAM domain protein
BC8716_21805	COG1271	oxidase subunit
BC8716_21810	COG1294	oxidase, subunit
BC8716_21820	COG1164	Oligoendopeptidase f
BC8716_21825	COG0753	catalase activity
BC8716_21835	COG1012	belongs to the aldehyde dehydrogenase family
BC8716_21840	COG3341	Caulimovirus viroplasmin
BC8716_21840	COG0328	RNA-DNA hybrid ribonuclease activity
BC8716_21850	COG2002	toxin-antitoxin pair type II binding
BC8716_21860	COG0733	neurotransmitter:sodium symporter activity
BC8716_21870	COG1077	Cell shape determining protein MreB Mrl
BC8716_21875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC8716_21875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_21875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC8716_21880	COG1105	Belongs to the carbohydrate kinase PfkB family
BC8716_21885	COG1349	DNA-binding transcription factor activity
BC8716_21890	COG0488	(ABC) transporter
BC8716_21895	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BC8716_21905	COG2188	Transcriptional regulator
BC8716_21910	COG0366	Alpha amylase catalytic
BC8716_21915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC8716_21915	COG1263	PTS System
BC8716_21925	COG1649	PFAM Uncharacterised BCR, COG1649
BC8716_21930	COG2244	polysaccharide biosynthetic process
BC8716_21935	COG1115	amino acid carrier protein
BC8716_21940	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC8716_21945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC8716_21960	COG1132	(ABC) transporter
BC8716_21965	COG1132	(ABC) transporter
BC8716_21970	COG3973	AAA domain
BC8716_21980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BC8716_21985	COG3639	organic phosphonate transmembrane transporter activity
BC8716_21990	COG3639	organic phosphonate transmembrane transporter activity
BC8716_21995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC8716_22030	COG0747	negative chemotaxis
BC8716_22035	COG4608	Belongs to the ABC transporter superfamily
BC8716_22040	COG0444	Belongs to the ABC transporter superfamily
BC8716_22050	COG2391	methyltransferase activity
BC8716_22060	COG4120	Belongs to the binding-protein-dependent transport system permease family
BC8716_22065	COG1116	anion transmembrane transporter activity
BC8716_22080	COG4208	sulfate ABC transporter
BC8716_22090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BC8716_22095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BC8716_22100	COG5002	protein histidine kinase activity
BC8716_22105	COG0277	FAD linked oxidase domain protein
BC8716_22110	COG0385	Bile acid
BC8716_22115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BC8716_22135	COG1396	sequence-specific DNA binding
BC8716_22155	COG1175	transmembrane transport