locus-tag	class	description
Bcoa_0001	COG0527	aspartate kinase activity
Bcoa_0002	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Bcoa_0003	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bcoa_0004	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bcoa_0005	COG1873	PFAM PRC-barrel domain
Bcoa_0006	COG0612	Peptidase, M16
Bcoa_0007	COG0726	polysaccharide deacetylase
Bcoa_0008	COG1185	polyribonucleotide nucleotidyltransferase activity
Bcoa_0009	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Bcoa_0010	COG0196	riboflavin kinase activity
Bcoa_0011	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Bcoa_0012	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Bcoa_0013	COG1550	Protein conserved in bacteria
Bcoa_0015	COG1358	cellular component organization or biogenesis
Bcoa_0016	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Bcoa_0017	COG0195	Participates in both transcription termination and antitermination
Bcoa_0018	COG0779	Required for maturation of 30S ribosomal subunits
Bcoa_0019	COG2176	DNA-directed DNA polymerase activity
Bcoa_0020	COG0442	prolyl-tRNA aminoacylation
Bcoa_0021	COG0750	zinc metalloprotease
Bcoa_0023	COG4589	Belongs to the CDS family
Bcoa_0024	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Bcoa_0025	COG0233	cytoplasmic translational termination
Bcoa_0026	COG0528	UMP kinase activity
Bcoa_0027	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Bcoa_0028	COG0052	Belongs to the universal ribosomal protein uS2 family
Bcoa_0030	COG1191	sigma factor activity
Bcoa_0031	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Bcoa_0032	COG1776	CheC inhibitor of MCP methylation
Bcoa_0033	COG0835	chemotaxis
Bcoa_0034	COG2198	Histidine kinase
Bcoa_0034	COG0643	Histidine kinase
Bcoa_0035	COG2201	protein-glutamate methylesterase activity
Bcoa_0036	COG0455	bacterial-type flagellum organization
Bcoa_0037	COG1419	protein localization to endoplasmic reticulum
Bcoa_0038	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bcoa_0039	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bcoa_0040	COG1684	flagellar biosynthetic protein fliR
Bcoa_0041	COG1987	bacterial-type flagellum assembly
Bcoa_0042	COG1338	Plays a role in the flagellum-specific transport system
Bcoa_0043	COG3190	flagellar
Bcoa_0044	COG2201	protein-glutamate methylesterase activity
Bcoa_0045	COG1776	CheC inhibitor of MCP methylation
Bcoa_0045	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bcoa_0046	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bcoa_0047	COG1580	Controls the rotational direction of flagella during chemotaxis
Bcoa_0048	COG4786	Flagellar basal body rod
Bcoa_0050	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Bcoa_0053	COG2882	bacterial-type flagellum organization
Bcoa_0054	COG1157	protein secretion by the type III secretion system
Bcoa_0055	COG1317	bacterial-type flagellum organization
Bcoa_0056	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bcoa_0057	COG1766	The M ring may be actively involved in energy transduction
Bcoa_0058	COG1677	Flagellar hook-basal body complex protein FliE
Bcoa_0059	COG1558	bacterial-type flagellum-dependent cell motility
Bcoa_0060	COG1815	bacterial-type flagellum-dependent cell motility
Bcoa_0061	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Bcoa_0063	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Bcoa_0064	COG4974	Belongs to the 'phage' integrase family
Bcoa_0067	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Bcoa_0068	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Bcoa_0069	COG0758	DNA mediated transformation
Bcoa_0070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Bcoa_0071	COG0045	succinate-CoA ligase (ADP-forming) activity
Bcoa_0072	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bcoa_0075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Bcoa_0078	COG0336	Belongs to the RNA methyltransferase TrmD family
Bcoa_0079	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Bcoa_0081	COG1837	Belongs to the UPF0109 family
Bcoa_0083	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Bcoa_0085	COG0552	protein localization to endoplasmic reticulum
Bcoa_0086	COG1196	nuclear chromosome segregation
Bcoa_0087	COG0571	ribonuclease III activity
Bcoa_0088	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Bcoa_0089	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Bcoa_0091	COG0416	fatty acid biosynthetic process
Bcoa_0092	COG1349	DNA-binding transcription factor activity
Bcoa_0092	COG2050	protein possibly involved in aromatic compounds catabolism
Bcoa_0093	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Bcoa_0094	COG1760	l-serine dehydratase
Bcoa_0095	COG1760	l-serine dehydratase
Bcoa_0096	COG1461	Dihydroxyacetone kinase
Bcoa_0097	COG1302	Protein conserved in bacteria
Bcoa_0098	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Bcoa_0099	COG1564	THIamine pyrophosphokinase
Bcoa_0100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Bcoa_0102	COG2815	serine threonine protein kinase
Bcoa_0102	COG0515	serine threonine protein kinase
Bcoa_0103	COG0631	protein serine/threonine phosphatase activity
Bcoa_0104	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Bcoa_0104	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Bcoa_0105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Bcoa_0106	COG0242	peptide deformylase activity
Bcoa_0107	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Bcoa_0108	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bcoa_0110	COG0194	GDP metabolic process
Bcoa_0111	COG2052	Domain of unknown function (DUF370)
Bcoa_0112	COG1561	YicC-like family, N-terminal region
Bcoa_0113	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Bcoa_0116	COG0385	Bile acid
Bcoa_0118	COG0720	synthase
Bcoa_0123	COG0561	phosphatase activity
Bcoa_0124	COG0628	permease
Bcoa_0126	COG1309	transcriptional regulator
Bcoa_0127	COG0477	Major facilitator Superfamily
Bcoa_0128	COG0477	Major facilitator Superfamily
Bcoa_0129	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Bcoa_0130	COG1803	Methylglyoxal synthase
Bcoa_0131	COG1454	alcohol dehydrogenase
Bcoa_0132	COG0235	Class ii aldolase
Bcoa_0133	COG4806	L-rhamnose isomerase
Bcoa_0134	COG1070	Carbohydrate kinase
Bcoa_0135	COG2207	Transcriptional regulator
Bcoa_0135	COG1917	Cupin 2, conserved barrel domain protein
Bcoa_0138	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Bcoa_0139	COG0284	orotidine-5'-phosphate decarboxylase activity
Bcoa_0140	COG0167	dihydroorotate dehydrogenase activity
Bcoa_0144	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Bcoa_0145	COG0540	Belongs to the ATCase OTCase family
Bcoa_0146	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Bcoa_0147	COG0564	pseudouridine synthase activity
Bcoa_0148	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Bcoa_0151	COG3599	regulation of cell shape
Bcoa_0152	COG2302	S4 RNA-binding domain
Bcoa_0153	COG0762	integral membrane protein
Bcoa_0154	COG1799	cell septum assembly
Bcoa_0155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Bcoa_0157	COG1388	LysM domain
Bcoa_0157	COG3584	3D domain protein
Bcoa_0158	COG1873	PFAM PRC-barrel domain
Bcoa_0159	COG1191	sigma factor activity
Bcoa_0160	COG1191	sigma factor activity
Bcoa_0163	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Bcoa_0164	COG0849	cell division
Bcoa_0165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Bcoa_0166	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Bcoa_0167	COG0772	Belongs to the SEDS family
Bcoa_0168	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Bcoa_0169	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Bcoa_0172	COG0768	penicillin binding
Bcoa_0174	COG4839	cell division protein FtsL
Bcoa_0175	COG0275	rRNA processing
Bcoa_0176	COG2001	Belongs to the MraZ family
Bcoa_0177	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
Bcoa_0178	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Bcoa_0179	COG0454	-acetyltransferase
Bcoa_0181	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Bcoa_0182	COG1399	metal-binding, possibly nucleic acid-binding protein
Bcoa_0183	COG1323	Belongs to the UPF0348 family
Bcoa_0184	COG3480	Lon protease (S16) C-terminal proteolytic domain
Bcoa_0185	COG1752	Esterase of the alpha-beta hydrolase superfamily
Bcoa_0186	COG3314	Sporulation integral membrane protein YlbJ
Bcoa_0187	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Bcoa_0188	COG0742	ribosomal rna small subunit methyltransferase
Bcoa_0191	COG3679	Belongs to the UPF0342 family
Bcoa_0195	COG2050	protein possibly involved in aromatic compounds catabolism
Bcoa_0196	COG2340	Cysteine-rich secretory protein family
Bcoa_0198	COG3336	cytochrome c oxidase
Bcoa_0199	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Bcoa_0203	COG0109	protoheme IX farnesyltransferase activity
Bcoa_0204	COG1612	heme a metabolic process
Bcoa_0205	COG0772	Belongs to the SEDS family
Bcoa_0206	COG4838	Belongs to the UPF0358 family
Bcoa_0207	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Bcoa_0208	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Bcoa_0212	COG0483	inositol monophosphate 1-phosphatase activity
Bcoa_0215	COG4476	Belongs to the UPF0223 family
Bcoa_0217	COG1982	Orn Lys Arg decarboxylase major
Bcoa_0225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bcoa_0227	COG1473	amidohydrolase
Bcoa_0228	COG2171	N-acyltransferase activity
Bcoa_0229	COG0583	DNA-binding transcription factor activity
Bcoa_0230	COG0517	IMP dehydrogenase activity
Bcoa_0231	COG4703	Protein of unknown function (DUF1797)
Bcoa_0233	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0236	COG1033	growth of symbiont in host cell
Bcoa_0236	COG2409	Drug exporters of the RND superfamily
Bcoa_0238	COG0835	chemotaxis
Bcoa_0238	COG0784	Response regulator, receiver
Bcoa_0239	COG0436	Aminotransferase
Bcoa_0240	COG2084	Dehydrogenase
Bcoa_0241	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0243	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcoa_0245	COG4873	Protein conserved in bacteria
Bcoa_0247	COG3949	Membrane
Bcoa_0248	COG0542	response to heat
Bcoa_0251	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Bcoa_0252	COG5002	protein histidine kinase activity
Bcoa_0256	COG0861	Integral membrane protein TerC family
Bcoa_0258	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Bcoa_0259	COG3852	Histidine kinase
Bcoa_0260	COG0673	inositol 2-dehydrogenase activity
Bcoa_0261	COG0783	Belongs to the Dps family
Bcoa_0262	COG0730	response to heat
Bcoa_0264	COG1959	2 iron, 2 sulfur cluster binding
Bcoa_0270	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Bcoa_0283	COG0842	Transport permease protein
Bcoa_0283	COG1511	domain protein
Bcoa_0286	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Bcoa_0287	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Bcoa_0293	COG1522	sequence-specific DNA binding
Bcoa_0294	COG2059	Chromate
Bcoa_0295	COG2059	Chromate
Bcoa_0296	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bcoa_0301	COG3579	cysteine-type endopeptidase activity
Bcoa_0302	COG1668	transmembrane transport
Bcoa_0303	COG4152	abc transporter atp-binding protein
Bcoa_0304	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0306	COG1940	carbohydrate kinase activity
Bcoa_0313	COG2382	esterase
Bcoa_0315	COG2153	protein acetylation
Bcoa_0320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bcoa_0328	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Bcoa_0329	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Bcoa_0330	COG0564	pseudouridine synthase activity
Bcoa_0331	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Bcoa_0332	COG2357	RelA SpoT domain protein
Bcoa_0335	COG0741	lytic transglycosylase activity
Bcoa_0338	COG2346	COG2346, Truncated hemoglobins
Bcoa_0341	COG1164	Oligoendopeptidase f
Bcoa_0342	COG4469	Competence protein
Bcoa_0343	COG4862	establishment of competence for transformation
Bcoa_0344	COG1393	Belongs to the ArsC family
Bcoa_0345	COG4608	Belongs to the ABC transporter superfamily
Bcoa_0346	COG0444	Belongs to the ABC transporter superfamily
Bcoa_0347	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bcoa_0348	COG0601	transmembrane transport
Bcoa_0349	COG4166	transmembrane transport
Bcoa_0352	COG0180	Tryptophanyl-tRNA synthetase
Bcoa_0354	COG0747	negative chemotaxis
Bcoa_0356	COG0601	transmembrane transport
Bcoa_0357	COG4608	Belongs to the ABC transporter superfamily
Bcoa_0360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Bcoa_0361	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bcoa_0367	COG2151	metal-sulfur cluster biosynthetic enzyme
Bcoa_0368	COG0561	phosphatase activity
Bcoa_0370	COG1307	EDD domain protein, DegV family
Bcoa_0371	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0374	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bcoa_0375	COG2311	Membrane
Bcoa_0381	COG1074	ATP-dependent DNA helicase activity
Bcoa_0382	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Bcoa_0386	COG0501	Belongs to the peptidase M48B family
Bcoa_0388	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Bcoa_0389	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_0390	COG0095	Lipoate-protein ligase
Bcoa_0393	COG1999	signal sequence binding
Bcoa_0394	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_0395	COG0697	spore germination
Bcoa_0396	COG2814	Major facilitator Superfamily
Bcoa_0397	COG3254	rhamnose metabolic process
Bcoa_0398	COG1349	DNA-binding transcription factor activity
Bcoa_0399	COG1263	PTS System
Bcoa_0399	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcoa_0399	COG2190	(PTS) system
Bcoa_0399	COG1263	PTS System
Bcoa_0399	COG2190	(PTS) system
Bcoa_0399	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcoa_0400	COG1511	domain protein
Bcoa_0401	COG1309	transcriptional regulator
Bcoa_0404	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Bcoa_0405	COG2329	Antibiotic biosynthesis monooxygenase
Bcoa_0406	COG3069	C4-dicarboxylate transmembrane transporter activity
Bcoa_0407	COG1473	amidohydrolase
Bcoa_0408	COG4473	ABC transporter
Bcoa_0409	COG1131	(ABC) transporter
Bcoa_0410	COG0537	adenosine 5'-monophosphoramidase activity
Bcoa_0413	COG1846	Transcriptional regulator
Bcoa_0415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Bcoa_0417	COG3481	metal-dependent phosphohydrolase, HD sub domain
Bcoa_0418	COG4717	serine-type aminopeptidase activity
Bcoa_0419	COG0420	3'-5' exonuclease activity
Bcoa_0420	COG3689	TIGRFAM TIGR03943 family protein
Bcoa_0421	COG0701	Predicted permease
Bcoa_0423	COG0861	Integral membrane protein TerC family
Bcoa_0425	COG1024	Enoyl-CoA hydratase
Bcoa_0426	COG0561	phosphatase activity
Bcoa_0428	COG4399	Belongs to the UPF0754 family
Bcoa_0430	COG0189	ligase activity
Bcoa_0431	COG0189	ligase activity
Bcoa_0433	COG2508	Transcriptional regulator
Bcoa_0434	COG3842	ATPase activity
Bcoa_0440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcoa_0442	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Bcoa_0443	COG1660	Displays ATPase and GTPase activities
Bcoa_0444	COG1051	belongs to the nudix hydrolase family
Bcoa_0446	COG0492	ferredoxin-NADP+ reductase activity
Bcoa_0447	COG0457	Tetratricopeptide repeat
Bcoa_0448	COG0110	maltose O-acetyltransferase activity
Bcoa_0449	COG0546	phosphoglycolate phosphatase activity
Bcoa_0450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Bcoa_0451	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Bcoa_0453	COG3595	metallopeptidase activity
Bcoa_0454	COG0463	Glycosyl transferase, family 2
Bcoa_0454	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Bcoa_0455	COG1682	transport, permease protein
Bcoa_0456	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Bcoa_0458	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Bcoa_0459	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Bcoa_0460	COG0556	nucleotide-excision repair
Bcoa_0469	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Bcoa_0471	COG0581	inorganic phosphate transmembrane transporter activity
Bcoa_0472	COG0573	inorganic phosphate transmembrane transporter activity
Bcoa_0473	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Bcoa_0476	COG5002	protein histidine kinase activity
Bcoa_0477	COG0745	RESPONSE REGULATOR receiver
Bcoa_0480	COG4607	ABC-type enterochelin transport system periplasmic component
Bcoa_0481	COG4604	ABC transporter, ATP-binding protein
Bcoa_0482	COG4605	iron ion homeostasis
Bcoa_0483	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bcoa_0484	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bcoa_0485	COG3409	Peptidoglycan-binding domain 1 protein
Bcoa_0485	COG0793	Belongs to the peptidase S41A family
Bcoa_0486	COG0460	homoserine dehydrogenase
Bcoa_0489	COG0739	heme binding
Bcoa_0490	COG2177	Part of the ABC transporter FtsEX involved in
Bcoa_0491	COG2884	Cell division ATP-binding protein ftsE
Bcoa_0493	COG2010	Cytochrome c
Bcoa_0494	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcoa_0495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Bcoa_0496	COG0653	protein targeting
Bcoa_0497	COG0405	Gamma-glutamyltransferase
Bcoa_0500	COG1516	flagellar protein fliS
Bcoa_0501	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Bcoa_0502	COG1334	flagellar protein FlaG
Bcoa_0504	COG2094	Belongs to the DNA glycosylase MPG family
Bcoa_0508	COG1067	ATP-dependent peptidase activity
Bcoa_0511	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Bcoa_0513	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bcoa_0514	COG4786	Flagellar basal body rod
Bcoa_0514	COG1256	bacterial-type flagellum assembly
Bcoa_0516	COG2747	anti-sigma28 factor FlgM
Bcoa_0518	COG1040	competence protein
Bcoa_0519	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Bcoa_0521	COG1307	EDD domain protein, DegV family
Bcoa_0522	COG0531	amino acid
Bcoa_0523	COG2197	response regulator
Bcoa_0525	COG1739	Uncharacterized protein family UPF0029
Bcoa_0526	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Bcoa_0527	COG0768	penicillin binding
Bcoa_0529	COG1388	LysM domain
Bcoa_0529	COG0791	NLP P60 protein
Bcoa_0532	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Bcoa_0533	COG0477	Major facilitator Superfamily
Bcoa_0535	COG1482	cell wall glycoprotein biosynthetic process
Bcoa_0536	COG0346	lactoylglutathione lyase activity
Bcoa_0537	COG2996	Protein conserved in bacteria
Bcoa_0541	COG1609	Transcriptional regulator
Bcoa_0543	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Bcoa_0544	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Bcoa_0547	COG1960	acyl-CoA dehydrogenase activity
Bcoa_0548	COG1960	acyl-CoA dehydrogenase activity
Bcoa_0549	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
Bcoa_0550	COG1033	growth of symbiont in host cell
Bcoa_0550	COG2409	Drug exporters of the RND superfamily
Bcoa_0553	COG2814	Major facilitator Superfamily
Bcoa_0554	COG1113	amino acid transport
Bcoa_0555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bcoa_0561	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Bcoa_0564	COG2226	methyltransferase
Bcoa_0567	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Bcoa_0568	COG3421	Type III restriction
Bcoa_0569	COG3344	reverse transcriptase
Bcoa_0570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bcoa_0571	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Bcoa_0574	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Bcoa_0576	COG0436	Aminotransferase
Bcoa_0577	COG0789	Transcriptional regulator
Bcoa_0579	COG1664	Polymer-forming cytoskeletal
Bcoa_0581	COG0534	Mate efflux family protein
Bcoa_0582	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bcoa_0583	COG4717	serine-type aminopeptidase activity
Bcoa_0584	COG0420	3'-5' exonuclease activity
Bcoa_0585	COG0431	NADPH-dependent FMN reductase
Bcoa_0586	COG0656	L-ascorbic acid biosynthetic process
Bcoa_0589	COG0656	L-ascorbic acid biosynthetic process
Bcoa_0593	COG0561	phosphatase activity
Bcoa_0595	COG1609	Transcriptional regulator
Bcoa_0599	COG1063	alcohol dehydrogenase
Bcoa_0603	COG0535	radical SAM domain protein
Bcoa_0606	COG0589	response to stress
Bcoa_0607	COG2244	polysaccharide biosynthetic process
Bcoa_0608	COG2746	aminoglycoside 3-N-acetyltransferase activity
Bcoa_0609	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0610	COG1960	acyl-CoA dehydrogenase activity
Bcoa_0611	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_0613	COG1268	BioY protein
Bcoa_0615	COG0024	Methionine aminopeptidase
Bcoa_0616	COG1388	LysM domain
Bcoa_0616	COG0791	NLP P60 protein
Bcoa_0619	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_0619	COG1454	alcohol dehydrogenase
Bcoa_0622	COG4145	pantothenate transmembrane transporter activity
Bcoa_0624	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Bcoa_0625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Bcoa_0628	COG0010	Belongs to the arginase family
Bcoa_0629	COG0460	homoserine dehydrogenase
Bcoa_0630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Bcoa_0631	COG0083	homoserine kinase activity
Bcoa_0632	COG1116	anion transmembrane transporter activity
Bcoa_0633	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcoa_0634	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcoa_0636	COG0154	amidase activity
Bcoa_0638	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Bcoa_0639	COG2079	MmgE PrpD family protein
Bcoa_0642	COG3716	PTS system mannose fructose sorbose family IID component
Bcoa_0643	COG3715	PTS system
Bcoa_0645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcoa_0645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcoa_0646	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Bcoa_0646	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Bcoa_0648	COG2706	6-phosphogluconolactonase activity
Bcoa_0649	COG0011	TIGRFAM Protein of
Bcoa_0651	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Bcoa_0652	COG1388	LysM domain
Bcoa_0652	COG3584	3D domain protein
Bcoa_0653	COG0039	L-malate dehydrogenase activity
Bcoa_0655	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Bcoa_0657	COG5002	protein histidine kinase activity
Bcoa_0658	COG0745	RESPONSE REGULATOR receiver
Bcoa_0659	COG1136	(ABC) transporter
Bcoa_0659	COG0577	efflux transmembrane transporter activity
Bcoa_0660	COG1136	(ABC) transporter
Bcoa_0662	COG1316	TRANSCRIPTIONal
Bcoa_0663	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Bcoa_0665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Bcoa_0667	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Bcoa_0668	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0672	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Bcoa_0673	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Bcoa_0674	COG0604	alcohol dehydrogenase
Bcoa_0677	COG2207	Transcriptional regulator
Bcoa_0678	COG1653	transport
Bcoa_0682	COG0626	cystathionine gamma-synthase activity
Bcoa_0683	COG0626	cystathionine gamma-synthase activity
Bcoa_0685	COG1131	(ABC) transporter
Bcoa_0687	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Bcoa_0688	COG3711	transcriptional antiterminator
Bcoa_0688	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcoa_0689	COG2723	6-phospho-beta-galactosidase activity
Bcoa_0690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bcoa_0690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bcoa_0693	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bcoa_0700	COG0473	3-isopropylmalate dehydrogenase activity
Bcoa_0707	COG2186	Transcriptional regulator
Bcoa_0708	COG1620	l-lactate permease
Bcoa_0710	COG0531	amino acid
Bcoa_0714	COG2972	Histidine kinase
Bcoa_0723	COG1363	Peptidase, m42
Bcoa_0726	COG1309	transcriptional regulator
Bcoa_0728	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_0729	COG1960	acyl-CoA dehydrogenase activity
Bcoa_0732	COG1501	Belongs to the glycosyl hydrolase 31 family
Bcoa_0733	COG3829	transcription factor binding
Bcoa_0733	COG3290	protein histidine kinase activity
Bcoa_0735	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_0738	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0740	COG4720	Psort location CytoplasmicMembrane, score
Bcoa_0745	COG2116	formate transmembrane transporter activity
Bcoa_0747	COG1104	cysteine desulfurase activity
Bcoa_0748	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Bcoa_0749	COG0157	Belongs to the NadC ModD family
Bcoa_0752	COG2115	Belongs to the xylose isomerase family
Bcoa_0753	COG1070	Carbohydrate kinase
Bcoa_0754	COG2814	Major facilitator Superfamily
Bcoa_0755	COG0371	Dehydrogenase
Bcoa_0758	COG0606	chelatase, subunit chli
Bcoa_0759	COG2272	Belongs to the type-B carboxylesterase lipase family
Bcoa_0760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcoa_0762	COG4297	protein containing double-stranded beta helix domain
Bcoa_0764	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_0765	COG0110	maltose O-acetyltransferase activity
Bcoa_0766	COG1510	regulation of RNA biosynthetic process
Bcoa_0767	COG0517	IMP dehydrogenase activity
Bcoa_0767	COG1125	glycine betaine transport
Bcoa_0768	COG1174	glycine betaine transport
Bcoa_0769	COG1732	Glycine betaine
Bcoa_0774	COG1609	Transcriptional regulator
Bcoa_0775	COG2814	Major facilitator Superfamily
Bcoa_0777	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bcoa_0780	COG1113	amino acid transport
Bcoa_0782	COG2190	(PTS) system
Bcoa_0782	COG2211	Major facilitator Superfamily
Bcoa_0783	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bcoa_0785	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bcoa_0786	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bcoa_0787	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcoa_0787	COG3711	transcriptional antiterminator
Bcoa_0789	COG2130	NADP-dependent
Bcoa_0790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Bcoa_0796	COG4989	oxidoreductase activity
Bcoa_0799	COG1316	TRANSCRIPTIONal
Bcoa_0802	COG0531	amino acid
Bcoa_0805	COG3867	Arabinogalactan endo-beta-1,4-galactanase
Bcoa_0807	COG2333	competence protein COMEC
Bcoa_0807	COG0658	competence protein
Bcoa_0810	COG2315	Protein conserved in bacteria
Bcoa_0812	COG0145	ligase activity
Bcoa_0814	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Bcoa_0824	COG3716	PTS system mannose fructose sorbose family IID component
Bcoa_0825	COG3715	PTS system
Bcoa_0826	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcoa_0826	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcoa_0832	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Bcoa_0832	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Bcoa_0833	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Bcoa_0834	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
Bcoa_0836	COG1396	sequence-specific DNA binding
Bcoa_0837	COG2188	Transcriptional regulator
Bcoa_0838	COG0363	glucosamine-6-phosphate deaminase activity
Bcoa_0839	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcoa_0840	COG3715	PTS system
Bcoa_0841	COG3716	PTS system mannose fructose sorbose family IID component
Bcoa_0846	COG2226	methyltransferase
Bcoa_0847	COG5504	Zn-dependent protease
Bcoa_0850	COG4193	domain, Protein
Bcoa_0855	COG1063	alcohol dehydrogenase
Bcoa_0857	COG1070	Carbohydrate kinase
Bcoa_0858	COG2115	Belongs to the xylose isomerase family
Bcoa_0864	COG0531	amino acid
Bcoa_0866	COG3665	Urea carboxylase-associated protein
Bcoa_0867	COG0439	Biotin carboxylase
Bcoa_0869	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Bcoa_0872	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Bcoa_0880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Bcoa_0881	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Bcoa_0882	COG4464	protein tyrosine phosphatase activity
Bcoa_0883	COG0489	protein tyrosine kinase activity
Bcoa_0884	COG3944	biosynthesis protein
Bcoa_0889	COG0646	methionine synthase
Bcoa_0889	COG1410	methionine synthase
Bcoa_0890	COG0646	methionine synthase
Bcoa_0890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Bcoa_0892	COG1316	TRANSCRIPTIONal
Bcoa_0893	COG0586	Pfam SNARE associated Golgi protein
Bcoa_0894	COG0586	Pfam SNARE associated Golgi protein
Bcoa_0896	COG1733	regulation of RNA biosynthetic process
Bcoa_0899	COG0765	amino acid transport
Bcoa_0900	COG0765	amino acid transport
Bcoa_0901	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bcoa_0904	COG0628	permease
Bcoa_0905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Bcoa_0907	COG0531	amino acid
Bcoa_0911	COG0423	glycine-tRNA ligase activity
Bcoa_0915	COG1902	pentaerythritol trinitrate reductase activity
Bcoa_0920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bcoa_0921	COG1301	dicarboxylic acid transport
Bcoa_0922	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Bcoa_0923	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Bcoa_0924	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Bcoa_0925	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Bcoa_0932	COG3973	AAA domain
Bcoa_0933	COG0463	Glycosyl transferase, family 2
Bcoa_0934	COG2851	Citrate transporter
Bcoa_0935	COG4565	transcriptional regulatory protein
Bcoa_0936	COG3290	protein histidine kinase activity
Bcoa_0937	COG0004	ammonium transporteR
Bcoa_0938	COG1979	alcohol dehydrogenase
Bcoa_0940	COG0531	amino acid
Bcoa_0945	COG1953	Uracil, thiamine, allantoin
Bcoa_0947	COG1454	alcohol dehydrogenase
Bcoa_0948	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bcoa_0950	COG0247	lactate metabolic process
Bcoa_0951	COG1139	Iron-sulfur cluster binding protein
Bcoa_0952	COG1556	Lactate utilization protein
Bcoa_0953	COG0531	amino acid
Bcoa_0955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Bcoa_0957	COG1176	ABC-type spermidine putrescine transport system, permease component I
Bcoa_0958	COG3842	ATPase activity
Bcoa_0960	COG0833	amino acid
Bcoa_0961	COG3104	oligopeptide transport
Bcoa_0963	COG1113	amino acid transport
Bcoa_0965	COG0667	Aldo Keto reductase
Bcoa_0966	COG5577	PFAM Coat F domain
Bcoa_0967	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Bcoa_0970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bcoa_0972	COG1609	Transcriptional regulator
Bcoa_0973	COG2848	UPF0210 protein
Bcoa_0974	COG3830	Belongs to the UPF0237 family
Bcoa_0976	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Bcoa_0979	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Bcoa_0979	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Bcoa_0980	COG0702	epimerase
Bcoa_0983	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Bcoa_0984	COG1442	glycosyl transferase family 8
Bcoa_0984	COG1216	Glycosyl transferase, family 2
Bcoa_0985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Bcoa_0989	COG0697	spore germination
Bcoa_0991	COG0745	RESPONSE REGULATOR receiver
Bcoa_0991	COG3706	GGDEF domain
Bcoa_0992	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_0993	COG0371	Dehydrogenase
Bcoa_0994	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Bcoa_0998	COG0175	sulfate reduction
Bcoa_0999	COG5434	Belongs to the glycosyl hydrolase 28 family
Bcoa_1002	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_1005	COG3226	Transcriptional regulator
Bcoa_1010	COG1309	transcriptional regulator
Bcoa_1011	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_1012	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_1014	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcoa_1015	COG0217	transcriptional regulatory protein
Bcoa_1020	COG1120	ATPase activity
Bcoa_1021	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bcoa_1022	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bcoa_1023	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bcoa_1025	COG2076	Multidrug Resistance protein
Bcoa_1026	COG2076	Multidrug Resistance protein
Bcoa_1032	COG0463	Glycosyl transferase, family 2
Bcoa_1033	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Bcoa_1034	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bcoa_1036	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bcoa_1039	COG2217	Heavy metal translocating P-type atpase
Bcoa_1041	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bcoa_1043	COG0716	FMN binding
Bcoa_1044	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Bcoa_1046	COG1070	Carbohydrate kinase
Bcoa_1049	COG2188	Transcriptional regulator
Bcoa_1050	COG0366	Alpha amylase catalytic
Bcoa_1051	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcoa_1051	COG1263	PTS System
Bcoa_1052	COG2190	(PTS) system
Bcoa_1053	COG1174	glycine betaine transport
Bcoa_1054	COG1125	glycine betaine transport
Bcoa_1054	COG0517	IMP dehydrogenase activity
Bcoa_1059	COG0183	Belongs to the thiolase family
Bcoa_1061	COG3425	synthase
Bcoa_1071	COG0477	Major facilitator Superfamily
Bcoa_1071	COG2814	Major facilitator Superfamily
Bcoa_1075	COG0519	Catalyzes the synthesis of GMP from XMP
Bcoa_1079	COG2814	Major facilitator Superfamily
Bcoa_1080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bcoa_1090	COG0477	Major facilitator Superfamily
Bcoa_1091	COG0840	transmembrane signaling receptor activity
Bcoa_1092	COG1695	Transcriptional regulator
Bcoa_1095	COG0840	transmembrane signaling receptor activity
Bcoa_1096	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Bcoa_1102	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Bcoa_1103	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Bcoa_1104	COG4856	YbbR-like protein
Bcoa_1105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Bcoa_1106	COG5662	AntiSigma factor
Bcoa_1107	COG1595	DNA-templated transcription, initiation
Bcoa_1112	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_1113	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Bcoa_1114	COG4988	ABC transporter
Bcoa_1115	COG1294	oxidase, subunit
Bcoa_1116	COG1271	oxidase subunit
Bcoa_1118	COG0726	polysaccharide deacetylase
Bcoa_1120	COG2194	sulfuric ester hydrolase activity
Bcoa_1122	COG0489	protein tyrosine kinase activity
Bcoa_1123	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bcoa_1125	COG0833	amino acid
Bcoa_1126	COG0529	Catalyzes the synthesis of activated sulfate
Bcoa_1127	COG2046	Belongs to the sulfate adenylyltransferase family
Bcoa_1131	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Bcoa_1132	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Bcoa_1134	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Bcoa_1135	COG1122	ATPase activity
Bcoa_1136	COG1122	ATPase activity
Bcoa_1138	COG0203	ribosomal protein L17
Bcoa_1139	COG0202	RNA polymerase activity
Bcoa_1140	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Bcoa_1141	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Bcoa_1142	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Bcoa_1143	COG0563	adenylate kinase activity
Bcoa_1144	COG0201	protein transport
Bcoa_1145	COG0200	Binds to the 23S rRNA
Bcoa_1146	COG1841	ribosomal large subunit assembly
Bcoa_1147	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Bcoa_1148	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Bcoa_1149	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Bcoa_1150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Bcoa_1151	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Bcoa_1153	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Bcoa_1154	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Bcoa_1155	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Bcoa_1156	COG0255	Belongs to the universal ribosomal protein uL29 family
Bcoa_1157	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Bcoa_1158	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Bcoa_1159	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Bcoa_1160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Bcoa_1161	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Bcoa_1162	COG0089	rRNA binding
Bcoa_1163	COG0088	Forms part of the polypeptide exit tunnel
Bcoa_1165	COG0051	transcription antitermination factor activity, RNA binding
Bcoa_1168	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Bcoa_1169	COG0049	tRNA binding
Bcoa_1170	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Bcoa_1171	COG1358	cellular component organization or biogenesis
Bcoa_1174	COG2813	Specifically methylates the guanine in position
Bcoa_1176	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Bcoa_1178	COG0081	regulation of translation
Bcoa_1179	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Bcoa_1180	COG0250	Participates in transcription elongation, termination and antitermination
Bcoa_1181	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bcoa_1183	COG3688	RNA-binding protein containing a PIN domain
Bcoa_1184	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bcoa_1186	COG0215	cysteine-tRNA ligase activity
Bcoa_1187	COG1045	serine acetyltransferase
Bcoa_1188	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Bcoa_1189	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Bcoa_1191	COG4956	integral membrane protein (PIN domain superfamily)
Bcoa_1192	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Bcoa_1194	COG0542	response to heat
Bcoa_1195	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Bcoa_1196	COG3880	PFAM UvrB UvrC protein
Bcoa_1204	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Bcoa_1206	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Bcoa_1207	COG0590	tRNA wobble adenosine to inosine editing
Bcoa_1208	COG3858	chitin binding
Bcoa_1208	COG1388	LysM domain
Bcoa_1209	COG1428	Deoxynucleoside kinase
Bcoa_1210	COG1428	Deoxynucleoside kinase
Bcoa_1211	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Bcoa_1212	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Bcoa_1215	COG0517	IMP dehydrogenase activity
Bcoa_1215	COG0516	GMP reductase activity
Bcoa_1222	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Bcoa_1223	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Bcoa_1224	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Bcoa_1225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bcoa_1226	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Bcoa_1227	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Bcoa_1228	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Bcoa_1230	COG0037	tRNA processing
Bcoa_1231	COG0515	serine threonine protein kinase
Bcoa_1232	COG2304	oxidoreductase activity
Bcoa_1233	COG2208	phosphoserine phosphatase activity
Bcoa_1234	COG1098	S1 RNA binding domain
Bcoa_1238	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Bcoa_1239	COG3956	TIGRFAM MazG family protein
Bcoa_1240	COG2244	polysaccharide biosynthetic process
Bcoa_1241	COG2002	toxin-antitoxin pair type II binding
Bcoa_1242	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Bcoa_1244	COG0193	aminoacyl-tRNA hydrolase activity
Bcoa_1245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Bcoa_1246	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Bcoa_1247	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Bcoa_1249	COG0577	efflux transmembrane transporter activity
Bcoa_1249	COG1136	(ABC) transporter
Bcoa_1253	COG0251	oxidation-reduction process
Bcoa_1254	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Bcoa_1255	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Bcoa_1257	COG4466	Protein conserved in bacteria
Bcoa_1259	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Bcoa_1261	COG0084	hydrolase, TatD family'
Bcoa_1263	COG2002	toxin-antitoxin pair type II binding
Bcoa_1264	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Bcoa_1265	COG2827	Endonuclease containing a URI domain
Bcoa_1266	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Bcoa_1267	COG4467	Involved in initiation control of chromosome replication
Bcoa_1268	COG1774	PSP1 C-terminal conserved region
Bcoa_1269	COG0470	DNA polymerase III
Bcoa_1270	COG1728	Protein conserved in bacteria
Bcoa_1271	COG3870	Protein conserved in bacteria
Bcoa_1273	COG1982	Orn Lys Arg decarboxylase major
Bcoa_1277	COG3437	response regulator, receiver
Bcoa_1278	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bcoa_1279	COG0187	DNA topoisomerase II activity
Bcoa_1281	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Bcoa_1282	COG2501	S4 domain
Bcoa_1283	COG0592	DNA-directed DNA polymerase activity
Bcoa_1284	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Bcoa_1285	COG0594	ribonuclease P activity
Bcoa_1286	COG0706	membrane insertase activity
Bcoa_1287	COG1847	R3H domain protein
Bcoa_1288	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Bcoa_1289	COG0445	tRNA wobble uridine modification
Bcoa_1290	COG0357	Ribosomal RNA small subunit methyltransferase G
Bcoa_1291	COG1475	DNA binding
Bcoa_1292	COG1192	Involved in chromosome partitioning
Bcoa_1293	COG1475	DNA binding
Bcoa_1294	COG1811	Na channel or pump
Bcoa_1296	COG0668	transmembrane transport
Bcoa_1297	COG4481	Protein conserved in bacteria
Bcoa_1298	COG0012	GTP binding
Bcoa_1299	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bcoa_1299	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bcoa_1300	COG0307	riboflavin synthase, alpha
Bcoa_1302	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Bcoa_1303	COG0360	Binds together with S18 to 16S ribosomal RNA
Bcoa_1305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Bcoa_1307	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Bcoa_1308	COG0359	binds to the 23S rRNA
Bcoa_1309	COG0305	Participates in initiation and elongation during chromosome replication
Bcoa_1310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Bcoa_1311	COG0745	RESPONSE REGULATOR receiver
Bcoa_1312	COG5002	protein histidine kinase activity
Bcoa_1313	COG4863	YycH protein
Bcoa_1314	COG4853	Protein conserved in bacteria
Bcoa_1315	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Bcoa_1316	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bcoa_1317	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Bcoa_1325	COG2197	response regulator
Bcoa_1326	COG4585	Histidine kinase
Bcoa_1327	COG0842	Transport permease protein
Bcoa_1328	COG1131	(ABC) transporter
Bcoa_1329	COG0477	Major facilitator Superfamily
Bcoa_1330	COG0579	oxidoreductase
Bcoa_1332	COG0765	amino acid transport
Bcoa_1334	COG1126	abc transporter atp-binding protein
Bcoa_1336	COG3457	Alanine racemase
Bcoa_1340	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcoa_1341	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Bcoa_1342	COG2188	Transcriptional regulator
Bcoa_1346	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Bcoa_1348	COG1132	(ABC) transporter
Bcoa_1349	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Bcoa_1350	COG0028	Belongs to the TPP enzyme family
Bcoa_1352	COG2814	Major facilitator Superfamily
Bcoa_1355	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bcoa_1356	COG1442	glycosyl transferase family 8
Bcoa_1357	COG0534	Mate efflux family protein
Bcoa_1360	COG1119	ATPase activity
Bcoa_1361	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Bcoa_1362	COG2011	ABC-type metal ion transport system permease component
Bcoa_1363	COG1464	Belongs to the NlpA lipoprotein family
Bcoa_1364	COG3275	phosphorelay sensor kinase activity
Bcoa_1366	COG1966	Carbon starvation protein
Bcoa_1367	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bcoa_1368	COG2966	Psort location CytoplasmicMembrane, score
Bcoa_1374	COG0367	asparagine synthase
Bcoa_1375	COG0583	DNA-binding transcription factor activity
Bcoa_1376	COG1380	Effector of murein hydrolase LrgA
Bcoa_1377	COG1346	cytolysis
Bcoa_1379	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Bcoa_1381	COG0745	RESPONSE REGULATOR receiver
Bcoa_1382	COG3850	Histidine kinase
Bcoa_1382	COG5002	protein histidine kinase activity
Bcoa_1385	COG1737	Transcriptional regulator
Bcoa_1386	COG1785	Belongs to the alkaline phosphatase family
Bcoa_1387	COG0514	ATP-dependent DNA helicase (RecQ)
Bcoa_1388	COG0561	phosphatase activity
Bcoa_1389	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bcoa_1391	COG0351	phosphomethylpyrimidine kinase
Bcoa_1397	COG4555	ABC transporter
Bcoa_1401	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Bcoa_1403	COG2363	Small membrane protein
Bcoa_1406	COG0280	phosphate acetyltransferase
Bcoa_1407	COG0095	Lipoate-protein ligase
Bcoa_1409	COG1078	dGTPase activity
Bcoa_1410	COG3465	dGTPase activity
Bcoa_1412	COG1994	Peptidase M50
Bcoa_1414	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bcoa_1415	COG0010	Belongs to the arginase family
Bcoa_1417	COG0018	arginyl-trna synthetase
Bcoa_1418	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bcoa_1419	COG0247	lactate metabolic process
Bcoa_1419	COG2181	nitrate reductase activity
Bcoa_1420	COG0183	Belongs to the thiolase family
Bcoa_1421	COG1960	acyl-CoA dehydrogenase activity
Bcoa_1422	COG1960	acyl-CoA dehydrogenase activity
Bcoa_1423	COG1309	transcriptional regulator
Bcoa_1424	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bcoa_1424	COG1703	isobutyryl-CoA mutase activity
Bcoa_1424	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bcoa_1426	COG1136	(ABC) transporter
Bcoa_1427	COG3343	RNA polymerase activity
Bcoa_1428	COG0504	CTP synthase activity
Bcoa_1429	COG1725	Transcriptional regulator
Bcoa_1430	COG1131	(ABC) transporter
Bcoa_1433	COG2204	response regulator
Bcoa_1434	COG0191	fructose-bisphosphate aldolase activity
Bcoa_1435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Bcoa_1436	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Bcoa_1437	COG1494	fructose-1,6-bisphosphatase
Bcoa_1438	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Bcoa_1439	COG0254	rRNA binding
Bcoa_1440	COG1435	thymidine kinase activity
Bcoa_1442	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Bcoa_1445	COG0009	L-threonylcarbamoyladenylate synthase
Bcoa_1446	COG1971	Probably functions as a manganese efflux pump
Bcoa_1449	COG0698	ribose 5-phosphate isomerase
Bcoa_1451	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Bcoa_1452	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Bcoa_1455	COG0356	it plays a direct role in the translocation of protons across the membrane
Bcoa_1456	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Bcoa_1458	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Bcoa_1459	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Bcoa_1460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Bcoa_1461	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Bcoa_1462	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Bcoa_1463	COG4836	Membrane
Bcoa_1465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Bcoa_1466	COG2385	sporulation resulting in formation of a cellular spore
Bcoa_1467	COG0739	heme binding
Bcoa_1468	COG1609	Transcriptional regulator
Bcoa_1469	COG1077	Cell shape determining protein MreB Mrl
Bcoa_1470	COG4786	Flagellar basal body rod
Bcoa_1471	COG4786	Flagellar basal body rod
Bcoa_1472	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Bcoa_1474	COG0629	single-stranded DNA binding
Bcoa_1477	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bcoa_1481	COG1253	flavin adenine dinucleotide binding
Bcoa_1482	COG0789	Transcriptional regulator
Bcoa_1483	COG1253	flavin adenine dinucleotide binding
Bcoa_1485	COG1181	Belongs to the D-alanine--D-alanine ligase family
Bcoa_1486	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Bcoa_1488	COG1554	hydrolase, family 65, central catalytic
Bcoa_1490	COG3833	ABC-type maltose transport systems, permease component
Bcoa_1491	COG1175	transmembrane transport
Bcoa_1492	COG2182	Extracellular solute-binding protein
Bcoa_1495	COG1609	Transcriptional regulator
Bcoa_1496	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Bcoa_1497	COG1280	lysine exporter protein (LysE YggA)
Bcoa_1499	COG0513	Belongs to the DEAD box helicase family
Bcoa_1500	COG0705	Rhomboid family
Bcoa_1501	COG0736	holo-[acyl-carrier-protein] synthase activity
Bcoa_1502	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Bcoa_1504	COG0864	Transcriptional regulator
Bcoa_1505	COG2337	Toxic component of a toxin-antitoxin (TA) module
Bcoa_1506	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcoa_1507	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcoa_1508	COG2172	sigma factor antagonist activity
Bcoa_1509	COG2208	phosphoserine phosphatase activity
Bcoa_1510	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcoa_1511	COG2172	sigma factor antagonist activity
Bcoa_1512	COG1191	sigma factor activity
Bcoa_1513	COG2208	phosphoserine phosphatase activity
Bcoa_1514	COG2183	response to ionizing radiation
Bcoa_1515	COG3091	SprT-like family
Bcoa_1519	COG0802	atpase or kinase
Bcoa_1520	COG1214	PFAM Peptidase M22, glycoprotease
Bcoa_1521	COG0456	acetyltransferase
Bcoa_1523	COG0488	(ABC) transporter
Bcoa_1525	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Bcoa_1526	COG0805	protein transport
Bcoa_1528	COG1266	CAAX protease self-immunity
Bcoa_1529	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Bcoa_1530	COG0459	protein refolding
Bcoa_1531	COG2246	polysaccharide biosynthetic process
Bcoa_1532	COG0463	Glycosyl transferase, family 2
Bcoa_1534	COG4948	Mandelate Racemase Muconate Lactonizing
Bcoa_1535	COG1335	isochorismatase
Bcoa_1536	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Bcoa_1537	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Bcoa_1538	COG0519	Catalyzes the synthesis of GMP from XMP
Bcoa_1538	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Bcoa_1546	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bcoa_1547	COG1120	ATPase activity
Bcoa_1551	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_1553	COG2391	methyltransferase activity
Bcoa_1555	COG0425	Belongs to the sulfur carrier protein TusA family
Bcoa_1558	COG1279	arginine transmembrane transporter activity
Bcoa_1559	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bcoa_1560	COG1959	2 iron, 2 sulfur cluster binding
Bcoa_1561	COG2910	NAD(P)H-binding
Bcoa_1562	COG3479	Phenolic acid decarboxylase
Bcoa_1563	COG1695	Transcriptional regulator
Bcoa_1564	COG1725	Transcriptional regulator
Bcoa_1565	COG1131	(ABC) transporter
Bcoa_1571	COG0471	metal ion transport
Bcoa_1573	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bcoa_1575	COG2814	Major facilitator Superfamily
Bcoa_1578	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bcoa_1579	COG1024	Enoyl-CoA hydratase
Bcoa_1580	COG0183	Belongs to the thiolase family
Bcoa_1581	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_1582	COG0824	Thioesterase
Bcoa_1587	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bcoa_1590	COG0842	Transport permease protein
Bcoa_1592	COG1131	(ABC) transporter
Bcoa_1593	COG3850	Histidine kinase
Bcoa_1594	COG2197	response regulator
Bcoa_1595	COG2814	Major facilitator Superfamily
Bcoa_1596	COG1132	(ABC) transporter
Bcoa_1598	COG2252	PERMEase
Bcoa_1599	COG3711	transcriptional antiterminator
Bcoa_1601	COG1301	dicarboxylic acid transport
Bcoa_1604	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Bcoa_1605	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Bcoa_1607	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Bcoa_1608	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Bcoa_1609	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Bcoa_1611	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Bcoa_1612	COG0047	phosphoribosylformylglycinamidine synthase activity
Bcoa_1613	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Bcoa_1614	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Bcoa_1615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Bcoa_1616	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Bcoa_1617	COG0138	bifunctional purine biosynthesis protein purh
Bcoa_1618	COG0151	Belongs to the GarS family
Bcoa_1621	COG1470	cell adhesion involved in biofilm formation
Bcoa_1622	COG4496	protein, YerC YecD
Bcoa_1623	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Bcoa_1624	COG0210	DNA helicase
Bcoa_1625	COG0210	DNA helicase
Bcoa_1627	COG4851	CamS sex pheromone cAM373 precursor
Bcoa_1628	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Bcoa_1629	COG2224	Isocitrate lyase
Bcoa_1630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Bcoa_1631	COG0154	amidase activity
Bcoa_1632	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Bcoa_1637	COG1597	lipid kinase activity
Bcoa_1638	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bcoa_1655	COG3716	PTS system mannose fructose sorbose family IID component
Bcoa_1663	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_1666	COG1064	alcohol dehydrogenase
Bcoa_1669	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bcoa_1671	COG0800	Aldolase
Bcoa_1675	COG0326	Molecular chaperone. Has ATPase activity
Bcoa_1677	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bcoa_1678	COG0765	amino acid transport
Bcoa_1679	COG1126	abc transporter atp-binding protein
Bcoa_1680	COG1764	response to oxidative stress
Bcoa_1681	COG2814	Major facilitator Superfamily
Bcoa_1682	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Bcoa_1683	COG1984	allophanate hydrolase subunit 2
Bcoa_1684	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Bcoa_1687	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Bcoa_1689	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bcoa_1691	COG2390	Transcriptional regulator
Bcoa_1693	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Bcoa_1696	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Bcoa_1700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcoa_1701	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bcoa_1702	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcoa_1703	COG1116	anion transmembrane transporter activity
Bcoa_1704	COG0431	NADPH-dependent FMN reductase
Bcoa_1705	COG5583	Uncharacterized small protein (DUF2292)
Bcoa_1706	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Bcoa_1706	COG3153	acetyltransferase
Bcoa_1714	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_1717	COG0154	amidase activity
Bcoa_1718	COG2272	Belongs to the type-B carboxylesterase lipase family
Bcoa_1721	COG0791	NLP P60 protein
Bcoa_1721	COG1388	LysM domain
Bcoa_1725	COG1132	(ABC) transporter
Bcoa_1726	COG1132	(ABC) transporter
Bcoa_1729	COG3876	Protein conserved in bacteria
Bcoa_1731	COG1472	Belongs to the glycosyl hydrolase 3 family
Bcoa_1732	COG0697	spore germination
Bcoa_1733	COG1278	Cold shock
Bcoa_1735	COG1691	(AIR) carboxylase
Bcoa_1736	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Bcoa_1737	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Bcoa_1740	COG2610	gluconate transmembrane transporter activity
Bcoa_1741	COG1606	tRNA processing
Bcoa_1742	COG2204	response regulator
Bcoa_1744	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Bcoa_1747	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Bcoa_1748	COG5002	protein histidine kinase activity
Bcoa_1752	COG1609	Transcriptional regulator
Bcoa_1753	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Bcoa_1756	COG2372	response to copper ion
Bcoa_1756	COG1276	copper resistance
Bcoa_1757	COG4549	nuclear export factor GLE1
Bcoa_1765	COG1609	Transcriptional regulator
Bcoa_1766	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bcoa_1767	COG1869	D-ribose catabolic process
Bcoa_1768	COG1129	ABC transporter
Bcoa_1769	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bcoa_1770	COG1879	ABC-type sugar transport system periplasmic component
Bcoa_1774	COG1929	Belongs to the glycerate kinase type-1 family
Bcoa_1775	COG1063	alcohol dehydrogenase
Bcoa_1777	COG1328	CTP reductase activity
Bcoa_1779	COG1301	dicarboxylic acid transport
Bcoa_1782	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Bcoa_1792	COG1619	proteins homologs of microcin C7 resistance protein MccF
Bcoa_1806	COG0517	IMP dehydrogenase activity
Bcoa_1806	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Bcoa_1807	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcoa_1807	COG1263	PTS System
Bcoa_1809	COG2190	(PTS) system
Bcoa_1810	COG0386	Belongs to the glutathione peroxidase family
Bcoa_1811	COG1280	lysine exporter protein (LysE YggA)
Bcoa_1815	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Bcoa_1816	COG1401	restriction endodeoxyribonuclease activity
Bcoa_1817	COG4268	DNA restriction-modification system
Bcoa_1827	COG5444	nuclease activity
Bcoa_1843	COG3588	fructose-bisphosphate aldolase
Bcoa_1845	COG0471	metal ion transport
Bcoa_1846	COG0281	malic enzyme
Bcoa_1847	COG2223	nitrite transmembrane transporter activity
Bcoa_1848	COG2181	nitrate reductase activity
Bcoa_1850	COG1140	nitrate reductase beta subunit
Bcoa_1851	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Bcoa_1859	COG0833	amino acid
Bcoa_1860	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Bcoa_1865	COG3829	transcription factor binding
Bcoa_1866	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Bcoa_1869	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bcoa_1870	COG1960	acyl-CoA dehydrogenase activity
Bcoa_1871	COG0439	Biotin carboxylase
Bcoa_1872	COG0511	ligase activity, forming carbon-carbon bonds
Bcoa_1873	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Bcoa_1874	COG1024	Enoyl-CoA hydratase
Bcoa_1875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Bcoa_1882	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Bcoa_1883	COG0210	DNA helicase
Bcoa_1884	COG2233	PERMEase
Bcoa_1885	COG0730	response to heat
Bcoa_1886	COG1113	amino acid transport
Bcoa_1887	COG0778	Nitroreductase
Bcoa_1902	COG2376	Dihydroxyacetone kinase
Bcoa_1903	COG1461	Dihydroxyacetone kinase
Bcoa_1904	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Bcoa_1906	COG0667	Aldo Keto reductase
Bcoa_1907	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Bcoa_1908	COG2357	RelA SpoT domain protein
Bcoa_1911	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Bcoa_1912	COG2814	Major facilitator Superfamily
Bcoa_1915	COG0561	phosphatase activity
Bcoa_1920	COG1349	DNA-binding transcription factor activity
Bcoa_1921	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Bcoa_1921	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Bcoa_1921	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bcoa_1922	COG0025	NhaP-type Na H and K H
Bcoa_1923	COG0166	Belongs to the GPI family
Bcoa_1925	COG1304	FMN binding
Bcoa_1935	COG1518	maintenance of DNA repeat elements
Bcoa_1937	COG1518	maintenance of DNA repeat elements
Bcoa_1938	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Bcoa_1943	COG3620	sequence-specific DNA binding
Bcoa_1947	COG0737	Belongs to the 5'-nucleotidase family
Bcoa_1948	COG1737	Transcriptional regulator
Bcoa_1949	COG4086	secreted protein
Bcoa_1953	COG2197	response regulator
Bcoa_1955	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bcoa_1957	COG0288	reversible hydration of carbon dioxide
Bcoa_1958	COG2226	methyltransferase
Bcoa_1959	COG1854	S-ribosylhomocysteine lyase activity
Bcoa_1960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bcoa_1961	COG0626	cystathionine gamma-synthase activity
Bcoa_1962	COG1585	Membrane protein implicated in regulation of membrane protease activity
Bcoa_1963	COG2268	Band 7 protein
Bcoa_1964	COG1077	Cell shape determining protein MreB Mrl
Bcoa_1965	COG1607	acyl-coa hydrolase
Bcoa_1966	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Bcoa_1968	COG3189	MarR family transcriptional regulator
Bcoa_1971	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Bcoa_1972	COG1360	Flagellar Motor Protein
Bcoa_1973	COG0693	protein deglycase activity
Bcoa_1974	COG0024	Methionine aminopeptidase
Bcoa_1975	COG4840	Belongs to the UPF0435 family
Bcoa_1976	COG1295	ribonuclease BN
Bcoa_1978	COG0477	Major facilitator Superfamily
Bcoa_1979	COG0387	Pfam Sodium calcium exchanger
Bcoa_1984	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Bcoa_1985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bcoa_2000	COG0798	PFAM Bile acid sodium symporter
Bcoa_2004	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Bcoa_2006	COG1846	Transcriptional regulator
Bcoa_2007	COG1132	(ABC) transporter
Bcoa_2010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Bcoa_2014	COG0840	transmembrane signaling receptor activity
Bcoa_2015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Bcoa_2016	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Bcoa_2017	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bcoa_2018	COG0477	Major facilitator Superfamily
Bcoa_2019	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
Bcoa_2025	COG2839	Protein conserved in bacteria
Bcoa_2026	COG1823	symporter activity
Bcoa_2029	COG3655	Transcriptional regulator
Bcoa_2030	COG3739	integral membrane protein
Bcoa_2031	COG5278	phosphoserine phosphatase activity
Bcoa_2031	COG0840	transmembrane signaling receptor activity
Bcoa_2038	COG1511	domain protein
Bcoa_2040	COG1309	transcriptional regulator
Bcoa_2041	COG2132	Multicopper oxidase
Bcoa_2044	COG0252	asparaginase activity
Bcoa_2045	COG3275	phosphorelay sensor kinase activity
Bcoa_2046	COG3279	Response regulator of the LytR AlgR family
Bcoa_2047	COG2223	nitrite transmembrane transporter activity
Bcoa_2048	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Bcoa_2049	COG0670	Belongs to the BI1 family
Bcoa_2050	COG2124	cytochrome p450
Bcoa_2052	COG1366	Belongs to the anti-sigma-factor antagonist family
Bcoa_2053	COG1114	Component of the transport system for branched-chain amino acids
Bcoa_2054	COG0129	dihydroxy-acid dehydratase activity
Bcoa_2055	COG0028	Belongs to the TPP enzyme family
Bcoa_2056	COG0440	acetolactate synthase activity
Bcoa_2057	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Bcoa_2058	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Bcoa_2060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Bcoa_2061	COG0066	3-isopropylmalate dehydratase activity
Bcoa_2062	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Bcoa_2065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Bcoa_2066	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Bcoa_2067	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bcoa_2068	COG0840	transmembrane signaling receptor activity
Bcoa_2070	COG0058	SHG alpha-glucan phosphorylase activity
Bcoa_2072	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_2072	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_2075	COG4585	Histidine kinase
Bcoa_2076	COG2197	response regulator
Bcoa_2085	COG1131	(ABC) transporter
Bcoa_2089	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Bcoa_2090	COG1136	(ABC) transporter
Bcoa_2090	COG0577	efflux transmembrane transporter activity
Bcoa_2091	COG0577	efflux transmembrane transporter activity
Bcoa_2093	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Bcoa_2093	COG0512	Glutamine amidotransferase of anthranilate synthase
Bcoa_2095	COG0134	indole-3-glycerol-phosphate synthase activity
Bcoa_2097	COG0159	tryptophan synthase activity
Bcoa_2102	COG1194	a g-specific adenine glycosylase
Bcoa_2103	COG1988	membrane-bound metal-dependent
Bcoa_2105	COG1131	(ABC) transporter
Bcoa_2108	COG0493	'glutamate synthase
Bcoa_2109	COG0069	glutamate synthase activity
Bcoa_2109	COG0070	glutamate synthase
Bcoa_2109	COG0067	glutamate synthase
Bcoa_2110	COG0583	DNA-binding transcription factor activity
Bcoa_2111	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_2114	COG3557	Belongs to the UPF0374 family
Bcoa_2115	COG1132	(ABC) transporter
Bcoa_2117	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Bcoa_2118	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bcoa_2118	COG1263	PTS System
Bcoa_2119	COG1737	Transcriptional regulator
Bcoa_2120	COG4129	membrane
Bcoa_2123	COG2814	Major facilitator Superfamily
Bcoa_2124	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcoa_2125	COG1116	anion transmembrane transporter activity
Bcoa_2126	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcoa_2127	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcoa_2128	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Bcoa_2132	COG0735	belongs to the Fur family
Bcoa_2133	COG0583	DNA-binding transcription factor activity
Bcoa_2134	COG0028	Belongs to the TPP enzyme family
Bcoa_2135	COG3527	Alpha-acetolactate decarboxylase
Bcoa_2141	COG2323	membrane
Bcoa_2142	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bcoa_2144	COG0697	spore germination
Bcoa_2145	COG2271	Major facilitator Superfamily
Bcoa_2148	COG1846	Transcriptional regulator
Bcoa_2149	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcoa_2153	COG5002	protein histidine kinase activity
Bcoa_2153	COG3850	Histidine kinase
Bcoa_2154	COG0745	RESPONSE REGULATOR receiver
Bcoa_2159	COG1131	(ABC) transporter
Bcoa_2162	COG0431	NADPH-dependent FMN reductase
Bcoa_2163	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Bcoa_2164	COG1882	Formate acetyltransferase
Bcoa_2166	COG2116	formate transmembrane transporter activity
Bcoa_2167	COG1126	abc transporter atp-binding protein
Bcoa_2168	COG0765	amino acid transport
Bcoa_2169	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bcoa_2170	COG0596	Alpha beta hydrolase
Bcoa_2171	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Bcoa_2173	COG2095	MarC family integral membrane protein
Bcoa_2176	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Bcoa_2177	COG2766	serine protein kinase
Bcoa_2178	COG2718	Belongs to the UPF0229 family
Bcoa_2181	COG0306	phosphate transporter
Bcoa_2182	COG1392	Phosphate transport regulator
Bcoa_2187	COG3594	Acyltransferase
Bcoa_2188	COG2719	SpoVR family
Bcoa_2191	COG0598	Magnesium transport protein CorA
Bcoa_2192	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Bcoa_2193	COG0601	transmembrane transport
Bcoa_2194	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bcoa_2195	COG0444	Belongs to the ABC transporter superfamily
Bcoa_2196	COG4166	transmembrane transport
Bcoa_2197	COG0791	NLP P60 protein
Bcoa_2198	COG4608	Belongs to the ABC transporter superfamily
Bcoa_2201	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bcoa_2206	COG0840	transmembrane signaling receptor activity
Bcoa_2209	COG3383	formate dehydrogenase (NAD+) activity
Bcoa_2214	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Bcoa_2218	COG0126	phosphoglycerate kinase activity
Bcoa_2220	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Bcoa_2221	COG0148	phosphopyruvate hydratase activity
Bcoa_2223	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bcoa_2224	COG1647	Serine aminopeptidase, S33
Bcoa_2225	COG0557	exoribonuclease II activity
Bcoa_2236	COG1414	Transcriptional regulator
Bcoa_2237	COG0800	Aldolase
Bcoa_2239	COG0246	Mannitol dehydrogenase
Bcoa_2240	COG2721	sulfolactate sulfo-lyase activity
Bcoa_2241	COG1904	glucuronate isomerase
Bcoa_2242	COG2211	Major facilitator Superfamily
Bcoa_2243	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_2244	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Bcoa_2246	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Bcoa_2249	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Bcoa_2250	COG1595	DNA-templated transcription, initiation
Bcoa_2253	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Bcoa_2255	COG0671	phosphoesterase, PA-phosphatase related
Bcoa_2256	COG0753	catalase activity
Bcoa_2257	COG2202	Pas domain
Bcoa_2257	COG2199	diguanylate cyclase activity
Bcoa_2257	COG2200	EAL domain
Bcoa_2259	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Bcoa_2262	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcoa_2263	COG0772	Belongs to the SEDS family
Bcoa_2264	COG5577	PFAM Coat F domain
Bcoa_2268	COG1024	Enoyl-CoA hydratase
Bcoa_2268	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bcoa_2269	COG0183	Belongs to the thiolase family
Bcoa_2270	COG1960	acyl-CoA dehydrogenase activity
Bcoa_2271	COG1393	Belongs to the ArsC family
Bcoa_2272	COG0509	glycine decarboxylation via glycine cleavage system
Bcoa_2273	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcoa_2275	COG0396	ATPase activity
Bcoa_2276	COG0719	Fe-S assembly protein
Bcoa_2277	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Bcoa_2278	COG0822	iron-sulfur transferase activity
Bcoa_2279	COG0719	Fe-S assembly protein
Bcoa_2280	COG0737	Belongs to the 5'-nucleotidase family
Bcoa_2281	COG3377	Domain of unknown function (DUF1805)
Bcoa_2283	COG0739	heme binding
Bcoa_2284	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Bcoa_2285	COG4470	Protein conserved in bacteria
Bcoa_2286	COG2445	Protein of unknown function DUF86
Bcoa_2287	COG0647	UMP catabolic process
Bcoa_2288	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Bcoa_2289	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Bcoa_2290	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Bcoa_2291	COG4837	Protein of unknown function (DUF1462)
Bcoa_2292	COG0316	Belongs to the HesB IscA family
Bcoa_2297	COG0492	ferredoxin-NADP+ reductase activity
Bcoa_2298	COG1252	NADH dehydrogenase
Bcoa_2300	COG3584	3D domain protein
Bcoa_2301	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Bcoa_2303	COG0697	spore germination
Bcoa_2305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Bcoa_2308	COG2050	protein possibly involved in aromatic compounds catabolism
Bcoa_2309	COG2814	Major facilitator Superfamily
Bcoa_2313	COG0492	ferredoxin-NADP+ reductase activity
Bcoa_2315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bcoa_2318	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Bcoa_2323	COG0656	L-ascorbic acid biosynthetic process
Bcoa_2326	COG1098	S1 RNA binding domain
Bcoa_2330	COG2155	Conserved Protein
Bcoa_2332	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Bcoa_2334	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_2337	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Bcoa_2338	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_2341	COG0840	transmembrane signaling receptor activity
Bcoa_2343	COG1609	Transcriptional regulator
Bcoa_2345	COG2160	L-arabinose isomerase activity
Bcoa_2346	COG4214	carbohydrate transport
Bcoa_2348	COG4213	ABC transporter substrate-binding protein
Bcoa_2349	COG1609	Transcriptional regulator
Bcoa_2354	COG2160	L-arabinose isomerase activity
Bcoa_2355	COG0235	Class ii aldolase
Bcoa_2358	COG2190	(PTS) system
Bcoa_2359	COG1525	nuclease
Bcoa_2360	COG1937	Protein conserved in bacteria
Bcoa_2361	COG0425	Belongs to the sulfur carrier protein TusA family
Bcoa_2361	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bcoa_2362	COG0038	chloride channel
Bcoa_2366	COG0726	polysaccharide deacetylase
Bcoa_2368	COG4221	oxidoreductase activity
Bcoa_2369	COG1388	LysM domain
Bcoa_2370	COG0745	RESPONSE REGULATOR receiver
Bcoa_2371	COG5002	protein histidine kinase activity
Bcoa_2377	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bcoa_2381	COG1522	sequence-specific DNA binding
Bcoa_2384	COG2608	mercury ion transmembrane transporter activity
Bcoa_2385	COG2217	Heavy metal translocating P-type atpase
Bcoa_2388	COG1285	pathogenesis
Bcoa_2396	COG1575	Belongs to the MenA family. Type 1 subfamily
Bcoa_2397	COG1169	isochorismate synthase
Bcoa_2398	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Bcoa_2399	COG0596	Alpha beta hydrolase
Bcoa_2400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Bcoa_2401	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_2402	COG4948	Mandelate Racemase Muconate Lactonizing
Bcoa_2404	COG0803	Belongs to the bacterial solute-binding protein 9 family
Bcoa_2406	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Bcoa_2407	COG0783	Belongs to the Dps family
Bcoa_2410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcoa_2411	COG1116	anion transmembrane transporter activity
Bcoa_2412	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcoa_2413	COG1070	Carbohydrate kinase
Bcoa_2414	COG0655	NAD(P)H dehydrogenase (quinone) activity
Bcoa_2415	COG1506	peptidase
Bcoa_2417	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Bcoa_2418	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Bcoa_2419	COG0367	asparagine synthase
Bcoa_2420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Bcoa_2421	COG2267	carboxylic ester hydrolase activity
Bcoa_2424	COG0275	rRNA processing
Bcoa_2426	COG2814	Major facilitator Superfamily
Bcoa_2427	COG0495	leucyl-tRNA aminoacylation
Bcoa_2431	COG2244	polysaccharide biosynthetic process
Bcoa_2432	COG1349	DNA-binding transcription factor activity
Bcoa_2433	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bcoa_2438	COG0510	thiamine kinase activity
Bcoa_2440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Bcoa_2441	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcoa_2442	COG5584	Small secreted protein
Bcoa_2443	COG1363	Peptidase, m42
Bcoa_2444	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Bcoa_2448	COG0784	Response regulator, receiver
Bcoa_2448	COG5002	protein histidine kinase activity
Bcoa_2449	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bcoa_2450	COG2208	phosphoserine phosphatase activity
Bcoa_2451	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcoa_2452	COG4848	Belongs to the UPF0354 family
Bcoa_2453	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bcoa_2455	COG1674	ftsk spoiiie
Bcoa_2456	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Bcoa_2458	COG4980	gas vesicle protein
Bcoa_2459	COG1605	Chorismate mutase
Bcoa_2459	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bcoa_2461	COG0123	including yeast histone deacetylase and acetoin utilization protein
Bcoa_2462	COG0517	IMP dehydrogenase activity
Bcoa_2463	COG0454	-acetyltransferase
Bcoa_2464	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bcoa_2466	COG4149	molybdate abc transporter
Bcoa_2467	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Bcoa_2468	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Bcoa_2471	COG0303	'Molybdopterin
Bcoa_2472	COG1763	Mo-molybdopterin cofactor biosynthetic process
Bcoa_2473	COG0314	molybdopterin synthase activity
Bcoa_2474	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Bcoa_2475	COG0315	cyclic pyranopterin monophosphate synthase activity
Bcoa_2476	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bcoa_2477	COG2427	Protein of unknown function (DUF1641)
Bcoa_2478	COG3383	formate dehydrogenase (NAD+) activity
Bcoa_2479	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Bcoa_2481	COG3290	protein histidine kinase activity
Bcoa_2481	COG3829	transcription factor binding
Bcoa_2482	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_2483	COG0506	proline dehydrogenase activity
Bcoa_2486	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Bcoa_2487	COG2199	diguanylate cyclase activity
Bcoa_2487	COG2203	Gaf domain
Bcoa_2488	COG1956	GAF domain-containing protein
Bcoa_2489	COG1309	transcriptional regulator
Bcoa_2490	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
Bcoa_2491	COG1104	cysteine desulfurase activity
Bcoa_2492	COG0301	tRNA thio-modification
Bcoa_2494	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bcoa_2495	COG0616	signal peptide processing
Bcoa_2496	COG1714	RDD family
Bcoa_2498	COG3874	Sporulation protein YtfJ
Bcoa_2499	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Bcoa_2500	COG0827	DNA restriction-modification system
Bcoa_2501	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Bcoa_2503	COG0589	response to stress
Bcoa_2505	COG0006	proline dipeptidase activity
Bcoa_2506	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Bcoa_2507	COG4109	DRTGG domain
Bcoa_2509	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Bcoa_2512	COG0587	DNA-directed DNA polymerase activity
Bcoa_2513	COG0281	malic enzyme
Bcoa_2514	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Bcoa_2515	COG0825	malonyl-CoA metabolic process
Bcoa_2516	COG0205	6-phosphofructokinase activity
Bcoa_2518	COG0628	permease
Bcoa_2519	COG2707	UPF0756 membrane protein
Bcoa_2520	COG0372	Belongs to the citrate synthase family
Bcoa_2521	COG0538	isocitrate dehydrogenase activity
Bcoa_2522	COG0039	L-malate dehydrogenase activity
Bcoa_2523	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bcoa_2523	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bcoa_2524	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Bcoa_2525	COG1971	Probably functions as a manganese efflux pump
Bcoa_2526	COG0237	dephospho-CoA kinase activity
Bcoa_2527	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Bcoa_2529	COG1473	amidohydrolase
Bcoa_2530	COG0747	negative chemotaxis
Bcoa_2531	COG0601	transmembrane transport
Bcoa_2533	COG0444	Belongs to the ABC transporter superfamily
Bcoa_2534	COG4608	Belongs to the ABC transporter superfamily
Bcoa_2539	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Bcoa_2540	COG3611	Membrane attachment protein
Bcoa_2541	COG1484	DNA-dependent DNA replication
Bcoa_2543	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Bcoa_2545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Bcoa_2546	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Bcoa_2547	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Bcoa_2554	COG0431	NADPH-dependent FMN reductase
Bcoa_2558	COG1695	Transcriptional regulator
Bcoa_2560	COG2329	Antibiotic biosynthesis monooxygenase
Bcoa_2567	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bcoa_2569	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Bcoa_2570	COG0072	phenylalanine-tRNA ligase activity
Bcoa_2570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bcoa_2572	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Bcoa_2573	COG1286	toxin biosynthetic process
Bcoa_2574	COG1796	DNA polymerase
Bcoa_2574	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bcoa_2575	COG1193	negative regulation of DNA recombination
Bcoa_2576	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_2577	COG1309	transcriptional regulator
Bcoa_2578	COG1024	Enoyl-CoA hydratase
Bcoa_2579	COG2086	electron transfer activity
Bcoa_2580	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Bcoa_2581	COG3118	belongs to the thioredoxin family
Bcoa_2582	COG0322	excinuclease ABC activity
Bcoa_2584	COG1719	4-vinyl reductase, 4VR
Bcoa_2585	COG2009	succinate dehydrogenase
Bcoa_2586	COG1053	succinate dehydrogenase
Bcoa_2587	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Bcoa_2588	COG0824	Thioesterase
Bcoa_2589	COG2197	response regulator
Bcoa_2593	COG1846	Transcriptional regulator
Bcoa_2596	COG5577	PFAM Coat F domain
Bcoa_2597	COG1063	alcohol dehydrogenase
Bcoa_2598	COG5577	PFAM Coat F domain
Bcoa_2600	COG5401	PFAM Sporulation and spore germination
Bcoa_2601	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Bcoa_2602	COG0622	Phosphoesterase
Bcoa_2606	COG0457	Tetratricopeptide repeat
Bcoa_2606	COG1477	protein flavinylation
Bcoa_2607	COG0544	peptidyl-prolyl cis-trans isomerase activity
Bcoa_2609	COG1067	ATP-dependent peptidase activity
Bcoa_2609	COG0470	DNA polymerase III
Bcoa_2610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Bcoa_2611	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Bcoa_2614	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bcoa_2615	COG0181	hydroxymethylbilane synthase activity
Bcoa_2617	COG0113	porphobilinogen synthase activity
Bcoa_2618	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Bcoa_2619	COG1388	LysM domain
Bcoa_2619	COG1388	LysM domain
Bcoa_2620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Bcoa_2622	COG0525	valine-tRNA ligase activity
Bcoa_2623	COG0285	dihydrofolate synthase activity
Bcoa_2630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Bcoa_2632	COG1459	type II secretion system
Bcoa_2637	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Bcoa_2639	COG2003	Belongs to the UPF0758 family
Bcoa_2642	COG1792	Involved in formation and maintenance of cell shape
Bcoa_2644	COG0850	regulation of cytokinetic process
Bcoa_2645	COG2894	cell division
Bcoa_2647	COG1994	Peptidase M50
Bcoa_2648	COG1530	ribonuclease E activity
Bcoa_2649	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Bcoa_2650	COG2868	ribosomal protein
Bcoa_2651	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Bcoa_2652	COG3290	protein histidine kinase activity
Bcoa_2653	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Bcoa_2654	COG4492	Belongs to the UPF0735 family
Bcoa_2655	COG0077	Prephenate dehydratase
Bcoa_2656	COG1827	regulation of RNA biosynthetic process
Bcoa_2657	COG1388	LysM domain
Bcoa_2659	COG0217	transcriptional regulatory protein
Bcoa_2660	COG0632	four-way junction helicase activity
Bcoa_2663	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Bcoa_2664	COG0343	queuine tRNA-ribosyltransferase activity
Bcoa_2665	COG1862	Preprotein translocase
Bcoa_2667	COG2323	membrane
Bcoa_2668	COG2244	polysaccharide biosynthetic process
Bcoa_2671	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bcoa_2671	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bcoa_2672	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Bcoa_2672	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Bcoa_2673	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Bcoa_2674	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Bcoa_2675	COG1490	D-aminoacyl-tRNA deacylase activity
Bcoa_2676	COG1846	Transcriptional regulator
Bcoa_2677	COG1566	PFAM secretion protein HlyD family protein
Bcoa_2678	COG2814	Major facilitator Superfamily
Bcoa_2679	COG3103	Sh3 type 3 domain protein
Bcoa_2679	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bcoa_2679	COG4991	sh3 domain protein
Bcoa_2681	COG0124	histidyl-tRNA synthetase
Bcoa_2682	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Bcoa_2684	COG0385	Bile acid
Bcoa_2685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Bcoa_2686	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Bcoa_2687	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_2690	COG1959	2 iron, 2 sulfur cluster binding
Bcoa_2691	COG1104	cysteine desulfurase activity
Bcoa_2692	COG0482	sulfurtransferase activity
Bcoa_2694	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Bcoa_2702	COG0628	permease
Bcoa_2703	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Bcoa_2704	COG4472	Bacterial protein of unknown function (DUF965)
Bcoa_2705	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Bcoa_2706	COG3906	Belongs to the UPF0473 family
Bcoa_2707	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Bcoa_2709	COG0572	uridine kinase
Bcoa_2710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Bcoa_2716	COG0450	alkyl hydroperoxide reductase
Bcoa_2717	COG3634	alkyl hydroperoxide reductase activity
Bcoa_2719	COG1183	phosphatidylcholine synthase activity
Bcoa_2725	COG1704	LemA family
Bcoa_2727	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcoa_2729	COG0071	Belongs to the small heat shock protein (HSP20) family
Bcoa_2730	COG2132	Multicopper oxidase
Bcoa_2732	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bcoa_2735	COG2210	Belongs to the sulfur carrier protein TusA family
Bcoa_2736	COG0071	Belongs to the small heat shock protein (HSP20) family
Bcoa_2737	COG2132	Multicopper oxidase
Bcoa_2738	COG3835	regulator
Bcoa_2739	COG0277	FAD linked oxidase domain protein
Bcoa_2740	COG0247	lactate metabolic process
Bcoa_2741	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Bcoa_2742	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Bcoa_2743	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Bcoa_2744	COG1534	Rna-binding protein
Bcoa_2745	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Bcoa_2746	COG1713	HD superfamily hydrolase involved in NAD metabolism
Bcoa_2747	COG0799	negative regulation of ribosome biogenesis
Bcoa_2748	COG2226	methyltransferase
Bcoa_2749	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bcoa_2750	COG1596	polysaccharide export
Bcoa_2750	COG1555	photosystem II stabilization
Bcoa_2751	COG2131	deaminase
Bcoa_2752	COG0658	competence protein
Bcoa_2752	COG2333	competence protein COMEC
Bcoa_2754	COG1466	dna polymerase III delta subunit
Bcoa_2755	COG0268	Binds directly to 16S ribosomal RNA
Bcoa_2756	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Bcoa_2757	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bcoa_2758	COG0481	GTPase activity
Bcoa_2759	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Bcoa_2761	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Bcoa_2762	COG0443	Heat shock 70 kDa protein
Bcoa_2764	COG2264	protein methyltransferase activity
Bcoa_2765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Bcoa_2766	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Bcoa_2767	COG1283	sodium-dependent phosphate transmembrane transporter activity
Bcoa_2770	COG1610	YqeY-like protein
Bcoa_2773	COG1702	phosphate starvation-inducible protein PhoH
Bcoa_2774	COG1480	7TM receptor with intracellular HD hydrolase
Bcoa_2775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Bcoa_2776	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Bcoa_2779	COG1381	Involved in DNA repair and RecF pathway recombination
Bcoa_2780	COG0517	IMP dehydrogenase activity
Bcoa_2782	COG0358	DNA primase activity
Bcoa_2783	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Bcoa_2785	COG2010	Cytochrome c
Bcoa_2786	COG2384	SAM-dependent methyltransferase
Bcoa_2787	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Bcoa_2788	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Bcoa_2791	COG0513	Belongs to the DEAD box helicase family
Bcoa_2792	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Bcoa_2793	COG3883	PFAM NLP P60 protein
Bcoa_2793	COG0791	NLP P60 protein
Bcoa_2795	COG1121	(ABC) transporter
Bcoa_2796	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bcoa_2797	COG0735	belongs to the Fur family
Bcoa_2798	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
Bcoa_2799	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Bcoa_2801	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Bcoa_2802	COG0477	Major facilitator Superfamily
Bcoa_2805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Bcoa_2807	COG0457	Tetratricopeptide repeat
Bcoa_2807	COG0705	Rhomboid family
Bcoa_2808	COG4483	Protein conserved in bacteria
Bcoa_2809	COG1940	carbohydrate kinase activity
Bcoa_2811	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcoa_2814	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Bcoa_2815	COG1459	type II secretion system
Bcoa_2816	COG4537	Required for transformation and DNA binding
Bcoa_2821	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Bcoa_2824	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bcoa_2825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Bcoa_2827	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Bcoa_2828	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bcoa_2829	COG0095	Lipoate-protein ligase
Bcoa_2830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bcoa_2832	COG0492	ferredoxin-NADP+ reductase activity
Bcoa_2833	COG1024	Enoyl-CoA hydratase
Bcoa_2834	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_2835	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bcoa_2836	COG0183	Belongs to the thiolase family
Bcoa_2837	COG3327	negative regulation of DNA-templated transcription, initiation
Bcoa_2839	COG1752	Esterase of the alpha-beta hydrolase superfamily
Bcoa_2841	COG3872	metal-dependent enzyme
Bcoa_2843	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Bcoa_2844	COG0006	proline dipeptidase activity
Bcoa_2845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Bcoa_2846	COG3854	ATPases associated with a variety of cellular activities
Bcoa_2854	COG0511	ligase activity, forming carbon-carbon bonds
Bcoa_2855	COG0439	Biotin carboxylase
Bcoa_2856	COG1302	Protein conserved in bacteria
Bcoa_2859	COG1570	exodeoxyribonuclease VII activity
Bcoa_2862	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Bcoa_2863	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Bcoa_2865	COG0497	DNA recombination
Bcoa_2866	COG0750	zinc metalloprotease
Bcoa_2868	COG0745	RESPONSE REGULATOR receiver
Bcoa_2869	COG0584	glycerophosphoryl diester phosphodiesterase
Bcoa_2871	COG3829	transcription factor binding
Bcoa_2871	COG3290	protein histidine kinase activity
Bcoa_2872	COG3290	protein histidine kinase activity
Bcoa_2872	COG3829	transcription factor binding
Bcoa_2874	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bcoa_2875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bcoa_2876	COG0022	dehydrogenase e1 component
Bcoa_2877	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bcoa_2878	COG1105	Belongs to the carbohydrate kinase PfkB family
Bcoa_2880	COG1376	ErfK ybiS ycfS ynhG family protein
Bcoa_2881	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bcoa_2883	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Bcoa_2884	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Bcoa_2886	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bcoa_2887	COG0300	oxidoreductase activity
Bcoa_2888	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Bcoa_2890	COG1388	LysM domain
Bcoa_2890	COG3858	chitin binding
Bcoa_2891	COG1073	alpha beta
Bcoa_2892	COG3853	Toxic anion resistance protein (TelA)
Bcoa_2893	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
Bcoa_2895	COG0667	Aldo Keto reductase
Bcoa_2898	COG1379	DNA repair
Bcoa_2899	COG1300	Membrane
Bcoa_2900	COG0735	belongs to the Fur family
Bcoa_2902	COG4974	Belongs to the 'phage' integrase family
Bcoa_2903	COG1686	Belongs to the peptidase S11 family
Bcoa_2906	COG1191	sigma factor activity
Bcoa_2910	COG0697	spore germination
Bcoa_2915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Bcoa_2916	COG1686	Belongs to the peptidase S11 family
Bcoa_2917	COG2715	membrane protein required for spore maturation
Bcoa_2918	COG0700	Nucleoside recognition
Bcoa_2919	COG1187	pseudouridine synthase activity
Bcoa_2920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bcoa_2921	COG1333	cytochrome c biogenesis protein
Bcoa_2922	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bcoa_2923	COG0745	RESPONSE REGULATOR receiver
Bcoa_2924	COG5002	protein histidine kinase activity
Bcoa_2925	COG0739	heme binding
Bcoa_2925	COG0741	lytic transglycosylase activity
Bcoa_2925	COG1196	nuclear chromosome segregation
Bcoa_2926	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Bcoa_2927	COG1141	Ferredoxin
Bcoa_2929	COG0514	ATP-dependent DNA helicase (RecQ)
Bcoa_2930	COG1266	CAAX protease self-immunity
Bcoa_2933	COG3546	catalase activity
Bcoa_2936	COG1408	metallophosphoesterase
Bcoa_2938	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Bcoa_2939	COG0492	ferredoxin-NADP+ reductase activity
Bcoa_2940	COG2339	peptidase activity
Bcoa_2941	COG3773	Cell wall hydrolase
Bcoa_2941	COG3409	Peptidoglycan-binding domain 1 protein
Bcoa_2942	COG2959	enzyme of heme biosynthesis
Bcoa_2943	COG2959	enzyme of heme biosynthesis
Bcoa_2944	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
Bcoa_2945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Bcoa_2946	COG0539	negative regulation of cytoplasmic translation
Bcoa_2949	COG1160	GTP binding
Bcoa_2953	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bcoa_2954	COG0776	regulation of translation
Bcoa_2956	COG0142	geranyltranstransferase activity
Bcoa_2957	COG2226	methyltransferase
Bcoa_2958	COG0142	geranyltranstransferase activity
Bcoa_2959	COG0105	UTP biosynthetic process
Bcoa_2960	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bcoa_2961	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Bcoa_2962	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Bcoa_2963	COG4401	Chorismate mutase type I
Bcoa_2964	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Bcoa_2965	COG0287	Prephenate dehydrogenase
Bcoa_2966	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Bcoa_2967	COG0457	Tetratricopeptide repeat
Bcoa_2968	COG5582	Belongs to the UPF0302 family
Bcoa_2971	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Bcoa_2973	COG4347	Protein of unknown function (DUF1405)
Bcoa_2975	COG2738	Putative neutral zinc metallopeptidase
Bcoa_2977	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcoa_2978	COG1694	Mazg nucleotide pyrophosphohydrolase
Bcoa_2979	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Bcoa_2980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bcoa_2981	COG0438	transferase activity, transferring glycosyl groups
Bcoa_2985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Bcoa_2986	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Bcoa_2987	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Bcoa_2987	COG1199	ATP-dependent helicase activity
Bcoa_2990	COG0017	Asparaginyl-tRNA synthetase
Bcoa_2991	COG3344	reverse transcriptase
Bcoa_2992	COG3935	DnaD domain protein
Bcoa_2993	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Bcoa_2995	COG4499	WXG100 protein secretion system (Wss), protein YukC
Bcoa_2995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bcoa_2996	COG3331	DNA recombination
Bcoa_3001	COG0071	Belongs to the small heat shock protein (HSP20) family
Bcoa_3002	COG1111	helicase
Bcoa_3002	COG1205	dead DEAH box helicase
Bcoa_3003	COG3359	exonuclease
Bcoa_3005	COG4474	Belongs to the UPF0398 family
Bcoa_3007	COG0116	Belongs to the methyltransferase superfamily
Bcoa_3008	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Bcoa_3010	COG2233	PERMEase
Bcoa_3013	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bcoa_3014	COG0789	Transcriptional regulator
Bcoa_3015	COG0174	glutamine synthetase
Bcoa_3016	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Bcoa_3018	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bcoa_3019	COG4224	UPF0291 protein
Bcoa_3022	COG3763	UPF0154 protein
Bcoa_3023	COG0785	Cytochrome C biogenesis protein
Bcoa_3024	COG2201	protein-glutamate methylesterase activity
Bcoa_3025	COG4846	Membrane protein involved in cytochrome C biogenesis
Bcoa_3027	COG0204	Acyl-transferase
Bcoa_3028	COG2027	D-alanyl-D-alanine carboxypeptidase
Bcoa_3029	COG1619	proteins homologs of microcin C7 resistance protein MccF
Bcoa_3033	COG3546	catalase activity
Bcoa_3036	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Bcoa_3037	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Bcoa_3038	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Bcoa_3039	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Bcoa_3040	COG0505	Belongs to the CarA family
Bcoa_3041	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Bcoa_3042	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Bcoa_3043	COG0137	argininosuccinate synthase activity
Bcoa_3044	COG0165	Argininosuccinate lyase
Bcoa_3045	COG0436	Aminotransferase
Bcoa_3050	COG0789	Transcriptional regulator
Bcoa_3051	COG4990	cell redox homeostasis
Bcoa_3053	COG2404	hydrolase activity, acting on ester bonds
Bcoa_3054	COG1252	NADH dehydrogenase
Bcoa_3056	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Bcoa_3057	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Bcoa_3058	COG0701	Predicted permease
Bcoa_3060	COG0709	Synthesizes selenophosphate from selenide and ATP
Bcoa_3061	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Bcoa_3063	COG0277	FAD linked oxidase domain protein
Bcoa_3064	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_3065	COG2030	dehydratase
Bcoa_3067	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Bcoa_3072	COG1131	(ABC) transporter
Bcoa_3073	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Bcoa_3075	COG0783	Belongs to the Dps family
Bcoa_3076	COG1914	H( )-stimulated, divalent metal cation uptake system
Bcoa_3077	COG0494	nUDIX hydrolase
Bcoa_3079	COG1247	-acetyltransferase
Bcoa_3084	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Bcoa_3085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Bcoa_3086	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Bcoa_3087	COG0297	glycogen (starch) synthase activity
Bcoa_3089	COG0708	Exodeoxyribonuclease III
Bcoa_3090	COG3773	Cell wall hydrolase
Bcoa_3091	COG2223	nitrite transmembrane transporter activity
Bcoa_3092	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_3093	COG0039	L-malate dehydrogenase activity
Bcoa_3096	COG2322	membrane
Bcoa_3097	COG0561	phosphatase activity
Bcoa_3099	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_3100	COG0183	Belongs to the thiolase family
Bcoa_3103	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Bcoa_3105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bcoa_3108	COG1511	domain protein
Bcoa_3108	COG3264	Mechanosensitive ion channel
Bcoa_3109	COG3284	Transcriptional regulator
Bcoa_3110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bcoa_3111	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bcoa_3112	COG0022	dehydrogenase e1 component
Bcoa_3113	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bcoa_3116	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bcoa_3117	COG0789	Transcriptional regulator
Bcoa_3119	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Bcoa_3120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Bcoa_3121	COG2045	Belongs to the ComB family
Bcoa_3122	COG1809	phosphosulfolactate synthase activity
Bcoa_3124	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bcoa_3125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bcoa_3126	COG2814	Major facilitator Superfamily
Bcoa_3127	COG1309	transcriptional regulator
Bcoa_3134	COG2258	MOSC domain
Bcoa_3137	COG0351	phosphomethylpyrimidine kinase
Bcoa_3138	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Bcoa_3139	COG1028	Short-chain dehydrogenase reductase Sdr
Bcoa_3140	COG0351	phosphomethylpyrimidine kinase
Bcoa_3141	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Bcoa_3143	COG0456	acetyltransferase
Bcoa_3144	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bcoa_3145	COG0456	acetyltransferase
Bcoa_3150	COG2226	methyltransferase
Bcoa_3151	COG0473	3-isopropylmalate dehydrogenase activity
Bcoa_3153	COG0681	Belongs to the peptidase S26 family
Bcoa_3155	COG2070	2-Nitropropane dioxygenase
Bcoa_3161	COG0574	Belongs to the PEP-utilizing enzyme family
Bcoa_3161	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Bcoa_3162	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Bcoa_3165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bcoa_3166	COG0187	DNA topoisomerase II activity
Bcoa_3167	COG1832	CoA-binding protein
Bcoa_3168	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Bcoa_3169	COG4841	protein insertion into membrane
Bcoa_3171	COG0824	Thioesterase
Bcoa_3175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Bcoa_3177	COG2309	aminopeptidase activity
Bcoa_3182	COG0318	PFAM AMP-dependent synthetase and ligase
Bcoa_3183	COG1346	cytolysis
Bcoa_3184	COG1380	Effector of murein hydrolase LrgA
Bcoa_3186	COG1132	(ABC) transporter
Bcoa_3187	COG1132	(ABC) transporter
Bcoa_3189	COG0477	Major facilitator Superfamily
Bcoa_3193	COG1113	amino acid transport
Bcoa_3195	COG5039	Polysaccharide pyruvyl transferase
Bcoa_3196	COG2814	Major facilitator Superfamily
Bcoa_3197	COG0640	Transcriptional regulator
Bcoa_3203	COG0745	RESPONSE REGULATOR receiver
Bcoa_3204	COG0642	Histidine kinase
Bcoa_3205	COG1136	(ABC) transporter
Bcoa_3206	COG0577	efflux transmembrane transporter activity
Bcoa_3209	COG3634	alkyl hydroperoxide reductase activity
Bcoa_3210	COG0302	gtp cyclohydrolase
Bcoa_3211	COG1278	Cold shock
Bcoa_3213	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bcoa_3215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Bcoa_3216	COG2807	transmembrane transport
Bcoa_3220	COG0569	domain protein
Bcoa_3221	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bcoa_3222	COG2962	Rard protein
Bcoa_3223	COG2391	methyltransferase activity
Bcoa_3225	COG0140	phosphoribosyl-ATP diphosphatase activity
Bcoa_3225	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Bcoa_3226	COG0107	imidazoleglycerol-phosphate synthase activity
Bcoa_3228	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Bcoa_3229	COG0131	Imidazoleglycerol-phosphate dehydratase
Bcoa_3230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Bcoa_3231	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Bcoa_3232	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Bcoa_3234	COG0598	Magnesium transport protein CorA
Bcoa_3235	COG1280	lysine exporter protein (LysE YggA)
Bcoa_3236	COG1113	amino acid transport
Bcoa_3238	COG3584	3D domain protein
Bcoa_3238	COG1388	LysM domain
Bcoa_3239	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bcoa_3239	COG0723	plastoquinol--plastocyanin reductase activity
Bcoa_3240	COG0516	GMP reductase activity
Bcoa_3240	COG0517	IMP dehydrogenase activity
Bcoa_3241	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bcoa_3243	COG2135	peptidase activity
Bcoa_3246	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bcoa_3248	COG0706	membrane insertase activity
Bcoa_3250	COG1012	belongs to the aldehyde dehydrogenase family
Bcoa_3251	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bcoa_3252	COG0567	Dehydrogenase, E1 component
Bcoa_3254	COG5002	protein histidine kinase activity
Bcoa_3255	COG0745	RESPONSE REGULATOR receiver
Bcoa_3256	COG2814	Major facilitator Superfamily
Bcoa_3257	COG1331	Highly conserved protein containing a thioredoxin domain
Bcoa_3260	COG1368	sulfuric ester hydrolase activity
Bcoa_3262	COG0671	phosphoesterase, PA-phosphatase related
Bcoa_3264	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Bcoa_3265	COG1793	dna ligase
Bcoa_3265	COG3285	dna ligase
Bcoa_3266	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Bcoa_3268	COG0534	Mate efflux family protein
Bcoa_3269	COG2340	Cysteine-rich secretory protein family
Bcoa_3270	COG1846	Transcriptional regulator
Bcoa_3271	COG3409	Peptidoglycan-binding domain 1 protein
Bcoa_3271	COG0793	Belongs to the peptidase S41A family
Bcoa_3273	COG1876	peptidase activity
Bcoa_3277	COG4479	Belongs to the UPF0346 family
Bcoa_3278	COG0840	transmembrane signaling receptor activity
Bcoa_3280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bcoa_3281	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bcoa_3282	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Bcoa_3282	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Bcoa_3284	COG2755	lipolytic protein G-D-S-L family
Bcoa_3285	COG1272	protein, Hemolysin III
Bcoa_3286	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Bcoa_3290	COG1413	lyase activity
Bcoa_3291	COG0488	(ABC) transporter
Bcoa_3292	COG1418	mRNA catabolic process
Bcoa_3294	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Bcoa_3296	COG1321	iron dependent repressor
Bcoa_3300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bcoa_3301	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Bcoa_3302	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Bcoa_3303	COG0464	growth
Bcoa_3306	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Bcoa_3312	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Bcoa_3313	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Bcoa_3315	COG4550	Control of competence regulator ComK, YlbF/YmcA
Bcoa_3316	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Bcoa_3320	COG0531	amino acid
Bcoa_3323	COG2359	stage V sporulation protein S
Bcoa_3324	COG1692	metallophosphoesterase
Bcoa_3325	COG1418	mRNA catabolic process
Bcoa_3327	COG1058	Belongs to the CinA family
Bcoa_3327	COG1546	Belongs to the CinA family
Bcoa_3328	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Bcoa_3329	COG1426	Protein conserved in bacteria
Bcoa_3332	COG0300	oxidoreductase activity
Bcoa_3333	COG0612	Peptidase, M16
Bcoa_3334	COG0612	Peptidase, M16
Bcoa_3340	COG1674	ftsk spoiiie
Bcoa_3340	COG4980	gas vesicle protein
Bcoa_3342	COG0740	serine-type endopeptidase activity
Bcoa_3343	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay