locus-tag	class	description
C3766_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C3766_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C3766_00015	ENOG410848D	S4 domain protein YaaA
C3766_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C3766_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3766_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3766_00040	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C3766_00075	ENOG4105CXN	decarboxylase
C3766_00080	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C3766_00085	ENOG4105X0R	protein from nitrogen regulatory protein P-II
C3766_00090	ENOG4105XVJ	Protein of unknown function (DUF327)
C3766_00095	ENOG4105FA2	dna polymerase iii
C3766_00100	ENOG4105MA4	psp1 domain protein
C3766_00105	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
C3766_00110	ENOG41060K3	Methyltransferase
C3766_00115	ENOG4105VC4	domain protein
C3766_00120	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C3766_00125	ENOG4105KRN	Transcriptional regulator, abrb family
C3766_00135	ENOG4105F8V	Hydrolase, tatD family
C3766_00140	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
C3766_00145	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C3766_00150	ENOG4105XFA	sporulation peptidase YabG
C3766_00160	ENOG4105W42	Veg protein
C3766_00175	ENOG4105DFT	pur operon repressor
C3766_00180	ENOG4105KME	endoribonuclease L-psp
C3766_00200	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3766_00210	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C3766_00215	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C3766_00220	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C3766_00225	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C3766_00235	ENOG4108JA2	transcriptioN-repair coupling factor
C3766_00240	ENOG4108M14	stage v sporulation protein t
C3766_00250	ENOG4108IY2	MazG family
C3766_00255	ENOG41082I2	s4 domain protein
C3766_00260	ENOG4105VYY	sporulation protein yabp
C3766_00275	ENOG41060GV	RNA binding s1 domain protein
C3766_00305	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C3766_00310	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C3766_00315	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C3766_00320	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C3766_00325	ENOG4105C6T	cysteine synthase
C3766_00330	ENOG4105EEI	dihydropteroate synthase
C3766_00335	ENOG4105KRF	dihydroneopterin aldolase
C3766_00340	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C3766_00420	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C3766_00430	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
C3766_00435	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
C3766_00445	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C3766_00455	ENOG4105ZMH	deoxynucleoside kinase
C3766_00465	ENOG4105VRS	hydrolase family 18
C3766_00475	ENOG4108Z6B	deaminase
C3766_00485	ENOG4105C6E	dna polymerase iii
C3766_00490	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C3766_00495	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C3766_00545	ENOG4108Z0C	Uvrb UvrC protein
C3766_00550	ENOG41066A3	ATP guanido phosphotransferase
C3766_00560	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C3766_00565	ENOG4105CTP	PilT protein domain protein
C3766_00570	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C3766_00575	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C3766_00585	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C3766_00590	ENOG4105D7W	serine acetyltransferase
C3766_00595	ENOG4105C8N	cysteinyl-tRNA synthetase
C3766_00605	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C3766_00610	ENOG4105M0M	Tetracycline resistance protein
C3766_00615	ENOG4105QIV	RNA polymerase
C3766_00625	ENOG410683Z	Preprotein translocase SecE subunit
C3766_00630	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C3766_00635	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C3766_00640	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C3766_00645	ENOG4108VZM	50s ribosomal protein L10
C3766_00650	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C3766_00655	ENOG4107Y49	methyltransferase
C3766_00665	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C3766_00670	ENOG4105XPM	ribosomal protein
C3766_00675	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C3766_00680	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C3766_00685	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C3766_00695	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C3766_00700	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C3766_00705	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C3766_00710	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C3766_00715	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C3766_00720	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C3766_00725	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C3766_00730	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C3766_00735	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C3766_00740	ENOG41082SA	50s ribosomal protein l29
C3766_00745	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C3766_00750	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C3766_00755	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C3766_00770	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C3766_00775	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C3766_00780	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C3766_00785	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C3766_00790	ENOG4105VPB	50S ribosomal protein L30
C3766_00795	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C3766_00800	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C3766_00805	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C3766_00810	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C3766_00820	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C3766_00825	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C3766_00830	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C3766_00835	ENOG4108ZT0	50S ribosomal protein l17
C3766_00840	ENOG4108JJB	ABC transporter
C3766_00845	ENOG4108JJB	ABC transporter
C3766_00850	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
C3766_00860	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C3766_00865	ENOG4108UJD	30S ribosomal protein S9
C3766_00885	ENOG4107RIQ	Sulfate adenylate transferase
C3766_00890	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
C3766_00895	ENOG4108IQI	permease
C3766_00910	ENOG4105D1F	ATP-binding protein
C3766_00940	ENOG4108NMV	polysaccharide deacetylase
C3766_00950	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C3766_00955	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C3766_00960	ENOG4108JJ9	ABC, transporter
C3766_00965	ENOG4108JJ8	(ABC) transporter
C3766_01045	ENOG4105EMN	RNA polymerase sigma factor
C3766_01055	ENOG4105C8B	TIGR00159 family
C3766_01060	ENOG4107U5W	ybbr family
C3766_01065	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C3766_01070	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C3766_01115	ENOG4105F27	Major Facilitator
C3766_01120	ENOG4107YNJ	LysR family Transcriptional regulator
C3766_01135	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C3766_01140	ENOG4106YBV	Methyl-accepting chemotaxis
C3766_01165	ENOG4105C8Q	Methyl-accepting chemotaxis
C3766_01170	ENOG41080V3	Major Facilitator superfamily
C3766_01225	ENOG4105DEN	Luciferase family
C3766_01245	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C3766_01265	ENOG4106K7D	Major facilitator family transporter
C3766_01300	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
C3766_01315	ENOG4105CHU	acetyl-coa acetyltransferase
C3766_01340	ENOG4108IJ8	ABC transporter
C3766_01345	ENOG4105E90	ABC transporter
C3766_01350	ENOG4105C5Y	PTS System
C3766_01355	ENOG4105C5Y	PTS System
C3766_01360	ENOG4105CG3	alpha amylase, catalytic region
C3766_01365	ENOG4107414	GntR family transcriptional regulator
C3766_01370	ENOG4105C6Z	Gluconate
C3766_01375	ENOG4105CMG	Carbohydrate kinase
C3766_01390	ENOG4105NQC	Flavodoxin
C3766_01405	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C3766_01415	ENOG4105DA5	(ABC) transporter
C3766_01435	ENOG410681U	heavy metal transport detoxification protein
C3766_01445	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C3766_01455	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C3766_01460	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C3766_01465	ENOG4105CKK	Glycosyl transferase, family 2
C3766_01490	ENOG4108UZ3	Transporter
C3766_01495	ENOG41080TC	multidrug resistance protein
C3766_01510	ENOG4105EHG	Permease protein
C3766_01515	ENOG4105DQ5	transport system permease protein
C3766_01530	ENOG4105E0A	ABC, transporter
C3766_01535	ENOG4105CAY	ferredoxin--nadp reductase
C3766_01560	ENOG4105CDY	transcriptional regulatory protein
C3766_01570	ENOG4105C1G	acyl-Coa dehydrogenase
C3766_01575	ENOG4105CHR	reductase
C3766_01585	ENOG41067SE	Tetr family transcriptional regulator
C3766_01605	ENOG4105C26	Dehydrogenase
C3766_01625	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
C3766_01635	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C3766_01640	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
C3766_01650	ENOG4108Z73	Siroheme synthase
C3766_01655	ENOG4108UIN	ybak prolyl-trna synthetase associated region
C3766_01660	ENOG4105DCT	glycerol dehydrogenase
C3766_01665	ENOG4105CEY	Amp-dependent synthetase and ligase
C3766_01670	ENOG4105BZU	Histidine kinase
C3766_01700	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C3766_01710	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C3766_01750	ENOG4105NAE	bifunctional deaminase-reductase domain protein
C3766_01770	ENOG4105CTS	PTS system mannitol-specific
C3766_01775	ENOG4105ETD	TRANSCRIPTIONal
C3766_01780	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
C3766_01785	ENOG4105C87	Aminotransferase class I and II
C3766_01795	ENOG4105VUC	UPF0237 protein
C3766_01800	ENOG4105CAG	UPF0210 protein
C3766_01805	ENOG4105EKQ	RNA-directed DNA polymerase
C3766_01810	ENOG4108M60	Transcriptional regulator
C3766_01820	ENOG4105D7K	pfkb domain protein
C3766_01835	ENOG41080HJ	6-phospho 3-hexuloisomerase
C3766_01855	ENOG4105CPC	Aldo Keto reductase
C3766_01865	ENOG4105C85	amino acid
C3766_01875	ENOG4105DUX	Transporter
C3766_01880	ENOG4108IQI	permease
C3766_01900	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C3766_01905	ENOG4105F38	ABC transporter, permease
C3766_01910	ENOG4108EG7	Binding-protein-dependent transport systems, inner membrane component
C3766_01915	ENOG4107RUE	extracellular solute-binding protein family 1
C3766_01950	ENOG4105CUB	amino acid
C3766_01955	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
C3766_01965	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C3766_01975	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C3766_01980	ENOG4105C0A	alcohol dehydrogenase
C3766_01985	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
C3766_01990	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
C3766_01995	ENOG4105BZ8	glutamate synthase
C3766_02000	ENOG4107SJI	Dehydrogenase
C3766_02015	ENOG4105D5Q	Arginine ornithine antiporter
C3766_02020	ENOG4107QW4	alcohol dehydrogenase
C3766_02025	ENOG4105BZU	Histidine kinase
C3766_02030	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C3766_02035	ENOG4108MRH	transcriptional regulatory protein
C3766_02040	ENOG4105D4T	Citrate transporter
C3766_02050	ENOG4105EEM	helicase
C3766_02085	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
C3766_02100	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C3766_02105	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C3766_02110	ENOG4107QJT	sodium dicarboxylate symporter
C3766_02115	ENOG4105IJJ	transcriptional regulator, crp fnr family
C3766_02135	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
C3766_02150	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C3766_02165	ENOG4105CPI	Metal Dependent Phosphohydrolase
C3766_02170	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C3766_02180	ENOG4105C0X	amino acid
C3766_02185	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C3766_02190	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C3766_02200	ENOG4106F5Q	Membrane
C3766_02215	ENOG4105CT1	(ABC) transporter
C3766_02220	ENOG4105EAD	ABC transporter
C3766_02225	ENOG4105DRP	amino acid AbC transporter
C3766_02240	ENOG4105KVH	Transcriptional regulator
C3766_02255	ENOG4107ZTW	SNARE associated Golgi
C3766_02260	ENOG4107T5V	SNARE associated Golgi
C3766_02265	ENOG4108RCF	TRANSCRIPTIONal
C3766_02310	ENOG4105HTX	biosynthesis protein
C3766_02315	ENOG4107YJ4	chain length determinant protein
C3766_02320	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
C3766_02325	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C3766_02330	ENOG4105D3Q	Sugar transferase
C3766_02340	ENOG4107VDP	teichoic acid biosynthesis
C3766_02375	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C3766_02385	ENOG4105ESI	atpase involved in dna repair
C3766_02395	ENOG4105CJQ	hydrolase, family 31
C3766_02405	ENOG4105C93	Xylose Isomerase
C3766_02410	ENOG4105CMG	Carbohydrate kinase
C3766_02440	ENOG4105CMG	Carbohydrate kinase
C3766_02455	ENOG4105D7V	transposase
C3766_02470	ENOG4105E2A	Dehydrogenase
C3766_02475	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C3766_02510	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
C3766_02515	ENOG4105DKG	l-rhamnose isomerase
C3766_02520	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
C3766_02525	ENOG4105C0A	alcohol dehydrogenase
C3766_02535	ENOG4105EDW	glycosyl transferase, family 39
C3766_02570	ENOG4108N67	choline binding protein
C3766_02590	ENOG4105CHR	reductase
C3766_02610	ENOG410787A	Pts system, glucitol sorbitol-specific
C3766_02615	ENOG4105DZY	Pts system, glucitol sorbitol-specific
C3766_02625	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C3766_02630	ENOG4108IMY	Transcriptional regulator
C3766_02635	ENOG4105ETE	Transcriptional regulator (LacI family
C3766_02640	ENOG4105NWF	RbsD or FucU transport
C3766_02645	ENOG4105C2J	ABC transporter
C3766_02650	ENOG4105CNN	ABC, transporter
C3766_02655	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C3766_02660	ENOG4105DET	Rhamnulokinase
C3766_02690	ENOG4105D2N	Aldolase
C3766_02695	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
C3766_02740	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
C3766_02750	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
C3766_02755	ENOG4105EA8	2-Nitropropane dioxygenase
C3766_02760	ENOG4105UNS	Pfam:DUF419
C3766_02770	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
C3766_02790	ENOG4105FB9	CRISPR-associated protein
C3766_02810	ENOG4107QTZ	amino acid
C3766_02820	ENOG4108KGH	TRANSCRIPTIONal
C3766_02830	ENOG4107QM2	Aldo Keto reductase
C3766_02865	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C3766_02875	ENOG4105EMD	TRANSCRIPTIONal
C3766_02880	ENOG4105VZJ	PTS System
C3766_02885	ENOG4105VCP	PTS System
C3766_02895	ENOG4105CK1	PTS System
C3766_02900	ENOG4107RBJ	symporter
C3766_02905	ENOG4105C85	amino acid
C3766_02920	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C3766_02925	ENOG4105EXW	epimerase dehydratase
C3766_02940	ENOG4105CZM	Major Facilitator
C3766_02950	ENOG4105CQ4	Transcriptional regulator
C3766_02955	ENOG4105C4C	beta-galactosidase
C3766_02970	ENOG4108HQR	Glycine betaine
C3766_02975	ENOG4105E90	ABC transporter
C3766_02980	ENOG4108IJ8	ABC transporter
C3766_02985	ENOG4107HG4	Transcriptional regulator
C3766_02990	ENOG4108UW5	maltose o-acetyltransferase
C3766_02995	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
C3766_03000	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
C3766_03010	ENOG4105Q95	Cupin 2, conserved barrel domain protein
C3766_03020	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C3766_03030	ENOG4105EBR	Carboxylesterase
C3766_03035	ENOG4105C0P	Mg chelatase subunit ChlI
C3766_03045	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
C3766_03055	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C3766_03060	ENOG4108IYU	L-aspartate oxidase
C3766_03075	ENOG4105TMB	Formate nitrite transporter
C3766_03080	ENOG4105C8Q	Methyl-accepting chemotaxis
C3766_03095	ENOG4105DTD	Dehydrogenase
C3766_03100	ENOG4105CY2	Citrate transporter
C3766_03110	ENOG4105C26	Dehydrogenase
C3766_03115	ENOG4105C0A	alcohol dehydrogenase
C3766_03130	ENOG4105CJQ	hydrolase, family 31
C3766_03140	ENOG4105C1G	acyl-Coa dehydrogenase
C3766_03155	ENOG41067SE	Tetr family transcriptional regulator
C3766_03170	ENOG4105CN9	Peptidase m42 family protein
C3766_03210	ENOG4105C2F	Histidine kinase
C3766_03215	ENOG4106YYS	transcriptional regulatory protein
C3766_03230	ENOG4105CUB	amino acid
C3766_03240	ENOG4105DAA	L-lactate
C3766_03245	ENOG4105JXH	GntR family transcriptional regulator
C3766_03260	ENOG4108KGH	TRANSCRIPTIONal
C3766_03275	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C3766_03310	ENOG4105VCP	PTS System
C3766_03325	ENOG4105CK1	PTS System
C3766_03330	ENOG4105CS2	ec 3.2.1.21
C3766_03335	ENOG4105EMD	TRANSCRIPTIONal
C3766_03340	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C3766_03345	ENOG4105C2X	Arabinose 5-phosphate isomerase
C3766_03380	ENOG4105C28	cystathionine
C3766_03385	ENOG4105C28	cystathionine
C3766_03405	ENOG4107T3P	ABC, transporter
C3766_03410	ENOG41075H3	AraC family transcriptional regulator
C3766_03455	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C3766_03460	ENOG41060D1	Quinol oxidase
C3766_03470	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C3766_03475	ENOG4105E2S	oxidase) subunit II
C3766_03480	ENOG4107YBY	Hydrolase
C3766_03485	ENOG4108KGH	TRANSCRIPTIONal
C3766_03495	ENOG4105C19	ABC transporter
C3766_03500	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3766_03505	ENOG4108STX	response regulator
C3766_03510	ENOG4105US7	Histidine kinase
C3766_03520	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C3766_03530	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C3766_03535	ENOG41069ER	domain protein
C3766_03545	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C3766_03560	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
C3766_03570	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C3766_03575	ENOG4108EQA	pts system
C3766_03585	ENOG4105ETZ	PTS System
C3766_03590	ENOG4105F3R	pts system mannose fructose sorbose family iid
C3766_03605	ENOG4105DXD	2-methylcitrate dehydratase
C3766_03610	ENOG4105CR4	methylisocitrate lyase
C3766_03620	ENOG4105DV0	amidase (EC 3.5.1.4
C3766_03630	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C3766_03635	ENOG4107Z6I	Thiamine biosynthesis protein
C3766_03645	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C3766_03650	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
C3766_03655	ENOG4105D6E	homoserine dehydrogenase
C3766_03670	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C3766_03675	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C3766_03685	ENOG4108IA2	Sodium pantothenate symporter
C3766_03700	ENOG4108EKI	Dehydrogenase
C3766_03725	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
C3766_03745	ENOG4105CSU	acyl-Coa dehydrogenase
C3766_03750	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C3766_03755	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
C3766_03765	ENOG4107YZX	Universal stress protein
C3766_03790	ENOG4105PGZ	NB-ARC domain
C3766_03795	ENOG4105CPQ	Dehydrogenase
C3766_03820	ENOG4108X4Q	Hydrolase
C3766_03840	ENOG4105CV8	reductase
C3766_03860	ENOG4107V0Z	fmn reductase
C3766_03870	ENOG41067QW	Transcriptional regulator
C3766_03875	ENOG4107VRP	DNA repair exonuclease
C3766_03880	ENOG4106D4I	domain protein
C3766_03885	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C3766_03890	ENOG4105UQX	Mate efflux family protein
C3766_03930	ENOG4105JSC	dimethylmenaquinone methyltransferase
C3766_03940	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C3766_03945	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C3766_03950	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C3766_03975	ENOG4105ETU	transcriptional activator (TenA
C3766_04010	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C3766_04015	ENOG4105C85	amino acid
C3766_04020	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3766_04040	ENOG4105EYF	MMPL domain protein
C3766_04045	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
C3766_04060	ENOG4105FDT	acyl-CoA dehydrogenase
C3766_04075	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C3766_04080	ENOG4105CMR	udp-glucose 4-epimerase
C3766_04085	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
C3766_04095	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
C3766_04115	ENOG4105QNR	S1 RNA binding domain protein
C3766_04120	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
C3766_04130	ENOG4105CVG	Homoserine O-transsuccinylase
C3766_04135	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3766_04140	ENOG4105CE4	GlcNAc 6-P deacetylase
C3766_04150	ENOG4105FDP	GntR family transcriptional regulator
C3766_04160	ENOG4107SDU	Methyl-accepting chemotaxis
C3766_04165	ENOG4107RVG	penicillin-binding protein
C3766_04175	ENOG4105ESV	Glycosyl transferase, family 4
C3766_04180	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C3766_04190	ENOG4105WH1	Two component transcriptional regulator luxr family
C3766_04195	ENOG4105CUB	amino acid
C3766_04210	ENOG4105MJ2	Competence protein
C3766_04230	ENOG4105E1Q	flagellar hook-associated protein
C3766_04235	ENOG4105DTJ	flagellar hook-associated protein
C3766_04240	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
C3766_04245	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
C3766_04250	ENOG4105I03	Flagellin
C3766_04255	ENOG4107TVC	Glycosyl transferase, family 2
C3766_04275	ENOG4108VX5	3-methyladenine DNA glycosylase
C3766_04290	ENOG41083S7	flagellar protein FlaG
C3766_04295	ENOG4107RT6	flagellar hook-associated
C3766_04300	ENOG4105MQ3	flagellar protein FliS
C3766_04315	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C3766_04325	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C3766_04345	ENOG4105CAK	Cell division ATP-binding protein ftsE
C3766_04350	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
C3766_04355	ENOG4105DR5	peptidase
C3766_04370	ENOG4105D6E	homoserine dehydrogenase
C3766_04380	ENOG4105CN1	protease
C3766_04395	ENOG4105DHS	permease protein
C3766_04400	ENOG4105CM4	permease protein
C3766_04405	ENOG4108IPW	abc transporter atp-binding protein
C3766_04425	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C3766_04430	ENOG4105BZU	Histidine kinase
C3766_04435	ENOG4105C1Q	protoporphyrinogen oxidase
C3766_04440	ENOG4105CVA	phosphate
C3766_04445	ENOG4105C8U	phosphate abc transporter
C3766_04450	ENOG4105E2Z	phosphate ABC transporter (Permease
C3766_04460	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C3766_04465	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C3766_04475	ENOG410838F	Glycosyl transferase family 2
C3766_04510	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C3766_04515	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C3766_04520	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
C3766_04530	ENOG4107SJB	teichoic acid biosynthesis
C3766_04540	ENOG4107SJB	teichoic acid biosynthesis
C3766_04545	ENOG4108PY7	
C3766_04555	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C3766_04565	ENOG4107XGZ	Hydrolase
C3766_04570	ENOG4108S4C	acetyltransferase
C3766_04580	ENOG4105C3M	thioredoxin reductase
C3766_04585	ENOG4108Z4K	mutator MutT protein
C3766_04590	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C3766_04595	ENOG4105CHW	UPF0052 protein
C3766_04605	ENOG4105KRI	phosphocarrier protein (HPr
C3766_04610	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C3766_04630	ENOG4105C9Q	fumarate hydratase class II
C3766_04635	ENOG4105YWU	small acid-soluble spore protein
C3766_04655	ENOG410839P	
C3766_04675	ENOG4108UH6	UPF0754 membrane protein
C3766_04690	ENOG4105CGU	Enoyl-CoA hydratase
C3766_04700	ENOG4108ZCF	integral membrane protein
C3766_04705	ENOG4108PJD	permease
C3766_04715	ENOG4107VRP	DNA repair exonuclease
C3766_04720	ENOG4106D4I	domain protein
C3766_04725	ENOG4105EQI	Metal Dependent Phosphohydrolase
C3766_04735	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C3766_04765	ENOG4105NBU	tryptophan transport protein
C3766_04770	ENOG4105K59	histidine triad (HIT) protein
C3766_04800	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
C3766_04805	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C3766_04820	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C3766_04825	ENOG4105C1Q	protoporphyrinogen oxidase
C3766_04840	ENOG4105ECB	domain protein
C3766_04845	ENOG4105C5Y	PTS System
C3766_04845	ENOG4105C5Y	PTS System
C3766_04850	ENOG4105E98	transcriptional regulator DeoR family
C3766_04855	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
C3766_04865	ENOG4108TVT	permease
C3766_04870	ENOG4105C26	Dehydrogenase
C3766_04875	ENOG4108KF3	Electron transport protein SCO1 SenC
C3766_04885	ENOG4106AXD	
C3766_04890	ENOG4105DF9	Lipoate-protein, ligase
C3766_04895	ENOG4105CEY	Amp-dependent synthetase and ligase
C3766_04905	ENOG4108UMN	azlc family
C3766_04915	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
C3766_04940	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C3766_04980	ENOG4105DHF	Membrane
C3766_04985	ENOG4105ERH	Fumarylacetoacetate hydrolase
C3766_05005	ENOG4105EPR	degv family
C3766_05010	ENOG41073B9	
C3766_05015	ENOG4108KP7	hydrolase
C3766_05020	ENOG4105VG1	fes assembly suf system protein
C3766_05050	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C3766_05055	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C3766_05070	ENOG4108JQ7	(ABC) transporter
C3766_05075	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C3766_05085	ENOG4105HJK	ABC transporter
C3766_05095	ENOG4105C31	Tryptophanyl-tRNA synthetase
C3766_05105	ENOG4108J59	Extracellular solute-binding protein, family 5
C3766_05110	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C3766_05115	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C3766_05125	ENOG4108JQ7	(ABC) transporter
C3766_05130	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
C3766_05150	ENOG4105DPN	Oligoendopeptidase f
C3766_05165	ENOG4105T58	Dithiol-disulfide isomerase
C3766_05170	ENOG4108Z18	K06886 hemoglobin
C3766_05185	ENOG4105E4C	Lytic transglycosylase catalytic
C3766_05205	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C3766_05210	ENOG4105EMS	pseudouridine synthase
C3766_05220	ENOG4107S1Q	Phosphatase
C3766_05225	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
C3766_05255	ENOG41090VF	Stage v sporulation protein ac
C3766_05260	ENOG4105CZ3	stage V sporulation protein ad
C3766_05310	ENOG4108ZMI	UPF0477 protein
C3766_05345	ENOG4105EVU	fructokinase
C3766_05355	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C3766_05360	ENOG4108IUX	(ABC) transporter
C3766_05365	ENOG4105RHA	ABC transporter, permease
C3766_05380	ENOG4105CTZ	aminopeptidase c
C3766_05385	ENOG4105DPN	Oligoendopeptidase f
C3766_05405	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C3766_05410	ENOG4105FGV	Chromate
C3766_05415	ENOG4105CAH	Chromate
C3766_05435	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C3766_05460	ENOG4107XVH	Transcriptional regulator
C3766_05465	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C3766_05490	ENOG4105DZR	Type I site-specific deoxyribonuclease
C3766_05515	ENOG4107KJX	Transcriptional regulator
C3766_05530	ENOG4107URF	beta-phospho-glucomutase
C3766_05570	ENOG4105CSH	Transporter
C3766_05575	ENOG4107QKS	N-acylglucosamine 2-epimerase
C3766_05580	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C3766_05640	ENOG4105HUF	DNA protection during starvation protein
C3766_05645	ENOG4105EE0	oxidoreductase
C3766_05650	ENOG4105BZU	Histidine kinase
C3766_05655	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C3766_05665	ENOG4107TS3	membrane protein, TerC
C3766_05670	ENOG410681C	small acid-soluble spore protein
C3766_05675	ENOG4105BZU	Histidine kinase
C3766_05680	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C3766_05705	ENOG4108K88	Membrane
C3766_05735	ENOG4105KRI	phosphocarrier protein (HPr
C3766_05740	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C3766_05745	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
C3766_05750	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C3766_05755	ENOG4105CHM	Aminotransferase
C3766_05760	ENOG4107R88	Chemotaxis protein (CheV)
C3766_05765	ENOG4105UIN	
C3766_05770	ENOG4105EYF	MMPL domain protein
C3766_05780	ENOG4105BZU	Histidine kinase
C3766_05790	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
C3766_05800	ENOG4107IN1	Protein of unknown function (DUF1797)
C3766_05815	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
C3766_05820	ENOG4105CH2	amidohydrolase
C3766_05835	ENOG4105CN5	Metallo-Beta-Lactamase
C3766_05840	ENOG4106148	UPF0356 protein
C3766_05880	ENOG4105CXN	decarboxylase
C3766_05885	ENOG4105WBI	UPF0223 protein
C3766_05900	ENOG4105ECY	inositol monophosphatase
C3766_05910	ENOG4105CI3	gtp-binding protein typa
C3766_05915	ENOG4105QA2	
C3766_05920	ENOG4108IAB	Phoh family
C3766_05935	ENOG4105CNI	cell division protein FtsW
C3766_05945	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C3766_05965	ENOG41064X9	cytochrome C oxidase subunit IV
C3766_05980	ENOG4106UY4	Inherit from COG: Scp-like extracellular
C3766_05985	ENOG4108VUY	thioesterase Superfamily protein
C3766_06020	ENOG4105WUC	UPF0298 protein
C3766_06035	ENOG4106H78	methyltransferase
C3766_06045	ENOG4105H20	Sporulation integral membrane protein YlbJ
C3766_06050	ENOG4105D78	K07001 NTE family protein
C3766_06055	ENOG41063PX	domain protein
C3766_06065	ENOG4105CDE	UPF0348 protein
C3766_06070	ENOG4105KNH	Nucleic acid-binding protein
C3766_06075	ENOG41067VY	50S ribosomal protein L32
C3766_06085	ENOG4108YG3	N-acetyltransferase
C3766_06090	ENOG4107S3C	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C3766_06095	ENOG41074B2	UPF0747 protein
C3766_06105	ENOG4108V6E	Cell division protein mraZ
C3766_06110	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C3766_06115	ENOG41068DC	Essential cell division protein (By similarity)
C3766_06120	ENOG4105CJN	penicillin-binding protein
C3766_06125	ENOG4105CJN	penicillin-binding protein
C3766_06130	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C3766_06140	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C3766_06145	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C3766_06150	ENOG4105CNI	cell division protein FtsW
C3766_06155	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C3766_06160	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
C3766_06165	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C3766_06170	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C3766_06175	ENOG4108AWX	Sporulation factor SpoIIGA 
C3766_06185	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C3766_06195	ENOG4105WR5	sporulation protein, YlmC YmxH family
C3766_06200	ENOG41069ER	domain protein
C3766_06205	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C3766_06210	ENOG4105DFA	alanine racemase domain protein
C3766_06215	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C3766_06220	ENOG41067XK	integral membrane protein
C3766_06225	ENOG4105DBK	s4 domain protein
C3766_06255	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C3766_06260	ENOG4105C34	Pseudouridine synthase
C3766_06270	ENOG4105CXT	aspartate transcarbamylase
C3766_06275	ENOG4105CD3	dihydroorotase
C3766_06295	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
C3766_06300	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C3766_06305	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C3766_06345	ENOG4106AXJ	AraC family transcriptional regulator
C3766_06350	ENOG4105DET	Rhamnulokinase
C3766_06355	ENOG4105DKG	l-rhamnose isomerase
C3766_06360	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
C3766_06365	ENOG4105C0A	alcohol dehydrogenase
C3766_06370	ENOG4108Z5K	methylglyoxal synthase
C3766_06375	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C3766_06380	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3766_06385	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3766_06390	ENOG4105J7D	transcriptional regulator
C3766_06405	ENOG4105C02	permease
C3766_06410	ENOG410667J	hydrolase
C3766_06420	ENOG4105CT4	transporter
C3766_06440	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C3766_06445	ENOG4105C09	Bile acid
C3766_06455	ENOG4105F23	Fibronectin-binding protein
C3766_06465	ENOG4105DSJ	YicC domain protein
C3766_06470	ENOG4105KC4	UPF0296 protein
C3766_06475	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C3766_06485	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C3766_06490	ENOG4105C25	Primosomal protein n'
C3766_06495	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C3766_06500	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C3766_06505	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C3766_06510	ENOG4108ZF3	Phosphatase
C3766_06515	ENOG4105D9P	serine threonine protein kinase
C3766_06520	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C3766_06525	ENOG4105DJV	ribulose-phosphate 3-epimerase
C3766_06530	ENOG4105FJ0	thiamine
C3766_06540	ENOG4105VB9	50S ribosomal protein l28
C3766_06550	ENOG4108ZAA	Alkaline-shock protein
C3766_06555	ENOG4105DP4	dak2 domain fusion protein ylov
C3766_06570	ENOG4105EJQ	L-serine dehydratase
C3766_06575	ENOG4105CB5	ATP-dependent DNA helicase recG
C3766_06580	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
C3766_06585	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C3766_06590	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C3766_06595	ENOG4105CHR	reductase
C3766_06600	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C3766_06605	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C3766_06610	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C3766_06615	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C3766_06630	ENOG4105K5M	30s ribosomal protein S16
C3766_06635	ENOG4108BW8	UPF0109 protein
C3766_06645	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C3766_06650	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C3766_06655	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C3766_06665	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
C3766_06680	ENOG4105D00	flagellar biosynthetic protein flhB
C3766_06685	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C3766_06690	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C3766_06695	ENOG4105C79	DNA protecting protein DprA
C3766_06700	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C3766_06715	ENOG4108HE4	integrase family
C3766_06720	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
C3766_06725	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
C3766_06730	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
C3766_06735	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
C3766_06740	ENOG4108ZC9	flagellar basal-body rod protein flgc
C3766_06745	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C3766_06750	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C3766_06755	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C3766_06770	ENOG4106YF4	Flagellar biosynthesis chaperone
C3766_06785	ENOG410822I	Flagellar hook capping protein
C3766_06795	ENOG4108JQA	flagellar
C3766_06810	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C3766_06815	ENOG4105DD5	Flagellar motor switch protein
C3766_06820	ENOG4107YTP	response regulator receiver protein
C3766_06830	ENOG4105CN7	Flagellar biosynthetic protein FliP
C3766_06835	ENOG4105VS8	Flagellar biosynthetic protein fliq
C3766_06840	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C3766_06845	ENOG4105D00	flagellar biosynthetic protein flhB
C3766_06850	ENOG4105D7B	Flagellar biosynthesis protein flha
C3766_06855	ENOG4105FZW	flagellar biosynthesis regulator FlhF
C3766_06865	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C3766_06870	ENOG4105CBS	Chea signal transduction histidine kinase
C3766_06875	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
C3766_06885	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
C3766_06890	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C3766_06900	ENOG4105CE9	30S ribosomal protein S2
C3766_06905	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C3766_06910	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C3766_06915	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C3766_06925	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C3766_06930	ENOG4105KNE	Phosphatidate cytidylyltransferase
C3766_06935	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C3766_06940	ENOG4105DZP	Membrane-associated zinc metalloprotease
C3766_06945	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C3766_06950	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C3766_06955	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C3766_06960	ENOG4105CHV	Transcription elongation factor NusA
C3766_06965	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
C3766_06970	ENOG4105VHM	ribosomal protein
C3766_06975	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C3766_06980	ENOG4105W7A	Protein of unknown function (DUF503)
C3766_06985	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C3766_06990	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C3766_06995	ENOG4105DTN	riboflavin biosynthesis protein ribF
C3766_07000	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C3766_07005	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C3766_07015	ENOG4105C1V	Peptidase, M16
C3766_07025	ENOG4105E35	Dipicolinate synthase subunit A
C3766_07030	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
C3766_07035	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C3766_07050	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C3766_07055	ENOG4105CN5	Metallo-Beta-Lactamase
C3766_07060	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
C3766_07070	ENOG4105CNU	cell division protein FtsK
C3766_07075	ENOG4105DIH	basic membrane
C3766_07080	ENOG4108JQ9	ABC transporter
C3766_07085	ENOG4105UIB	(ABC) transporter
C3766_07105	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
C3766_07110	ENOG4105XZV	Protein of unknown function (DUF3243)
C3766_07125	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C3766_07130	ENOG4105CEV	competence damage-inducible protein
C3766_07140	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
C3766_07145	ENOG4105D48	metallophosphoesterase
C3766_07150	ENOG4105MCT	stage V sporulation protein S
C3766_07155	ENOG4105XYU	peptidase (U32 family)
C3766_07160	ENOG4105CFP	Peptidase U32
C3766_07170	ENOG4108JUB	Transcriptional regulator
C3766_07175	ENOG4105C26	Dehydrogenase
C3766_07180	ENOG4105C8Y	Acetylornithine aminotransferase
C3766_07185	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C3766_07200	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C3766_07205	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C3766_07210	ENOG4105X3H	Excalibur domain protein
C3766_07235	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C3766_07250	ENOG4106F1P	AAA ATPase, central domain protein
C3766_07255	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C3766_07260	ENOG4105CXI	aluminum resistance protein
C3766_07285	ENOG4105KST	dependent repressor
C3766_07295	ENOG4105CKU	formyltetrahydrofolate synthetase
C3766_07310	ENOG4105C5H	ABC transporter
C3766_07320	ENOG4108Y6J	UPF0403 protein
C3766_07335	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C3766_07340	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
C3766_07345	ENOG4108UT2	hemolysin iii
C3766_07350	ENOG41090WU	lipolytic protein G-D-S-L family
C3766_07360	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C3766_07365	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C3766_07370	ENOG4105E0X	reductase
C3766_07380	ENOG4105C8Q	Methyl-accepting chemotaxis
C3766_07385	ENOG4105VSD	UPF0346 protein
C3766_07405	ENOG4108VXD	carboxy-peptidase
C3766_07420	ENOG4105K4I	Scp-like extracellular
C3766_07425	ENOG4107QMU	Mate efflux family protein
C3766_07435	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C3766_07440	ENOG4105DQE	DNA ligase
C3766_07445	ENOG4105FDF	Could be involved in DNA repair (By similarity)
C3766_07450	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C3766_07485	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3766_07490	ENOG4105GR3	Histidine kinase
C3766_07500	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C3766_07505	ENOG4105C7S	Dehydrogenase
C3766_07510	ENOG4105C26	Dehydrogenase
C3766_07530	ENOG4108JYZ	YitT family
C3766_07535	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C3766_07540	ENOG4105C72	UPF0176 protein
C3766_07550	ENOG4108RAV	Conserved protein
C3766_07565	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C3766_07575	ENOG41069ER	domain protein
C3766_07605	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
C3766_07610	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C3766_07615	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C3766_07620	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C3766_07625	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C3766_07635	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C3766_07640	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C3766_07650	ENOG41066VF	YeeE YedE family protein
C3766_07655	ENOG4105FR1	rard protein
C3766_07685	ENOG4105DJ2	Major Facilitator Superfamily
C3766_07700	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C3766_07720	ENOG4105EUJ	GTP cyclohydrolase i
C3766_07730	ENOG4105C3M	thioredoxin reductase
C3766_07750	ENOG4105C19	ABC transporter
C3766_07755	ENOG4105EWM	Histidine kinase
C3766_07760	ENOG4105CJZ	response regulator
C3766_07790	ENOG4105WAB	arsR family transcriptional regulator
C3766_07795	ENOG4108RWP	Major Facilitator Superfamily protein
C3766_07810	ENOG4108R1P	
C3766_07825	ENOG41080V3	Major Facilitator superfamily
C3766_07835	ENOG4105BZ1	(ABC) transporter
C3766_07840	ENOG4105BZ1	(ABC) transporter
C3766_07855	ENOG41067MG	lrgb family
C3766_07860	ENOG4105CEY	Amp-dependent synthetase and ligase
C3766_07875	ENOG41076DU	acid-soluble spore protein P
C3766_07885	ENOG4105C88	aminopeptidase
C3766_07890	ENOG410746C	Acid-soluble spore protein O
C3766_07895	ENOG4108I0Z	Aconitate hydratase
C3766_07910	ENOG41067CD	Small, acid-soluble spore protein Tlp
C3766_07920	ENOG4105MI2	
C3766_07925	ENOG4105W8X	HesB YadR YfhF-family protein
C3766_07930	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C3766_07935	ENOG4105K4P	CoA-binding domain protein
C3766_07940	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C3766_07990	ENOG4105EA8	2-Nitropropane dioxygenase
C3766_08010	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C3766_08020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C3766_08045	ENOG4108W0I	acetyltransferase
C3766_08060	ENOG4105CHR	reductase
C3766_08065	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
C3766_08070	ENOG4105DWF	phosphomethylpyrimidine kinase
C3766_08080	ENOG4108RPX	mosc domain containing protein
C3766_08115	ENOG4105YA8	Transcriptional regulator
C3766_08120	ENOG4107Y80	Major Facilitator superfamily
C3766_08125	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C3766_08145	ENOG41061P3	phosphosulfolactate synthase
C3766_08150	ENOG4108N5B	2-phosphosulfolactate phosphatase
C3766_08155	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C3766_08160	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
C3766_08170	ENOG4107TXC	Transcriptional regulator
C3766_08175	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C3766_08185	ENOG4107RUY	(E1 component), alpha subunit
C3766_08205	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C3766_08210	ENOG4105EGS	Mechanosensitive ion channel
C3766_08225	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
C3766_08235	ENOG4108UVJ	appr-1-p processing domain protein
C3766_08240	ENOG41069DP	small acid-soluble spore protein
C3766_08250	ENOG4105CHU	acetyl-coa acetyltransferase
C3766_08255	ENOG4105CEY	Amp-dependent synthetase and ligase
C3766_08265	ENOG4108X4Q	Hydrolase
C3766_08270	ENOG4108SJC	Membrane
C3766_08285	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C3766_08290	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C3766_08295	ENOG4105EU0	Major facilitator Superfamily
C3766_08310	ENOG4105CGK	Exodeoxyribonuclease III
C3766_08320	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
C3766_08330	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C3766_08335	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C3766_08360	ENOG4107TCE	N-acetyltransferase
C3766_08365	ENOG4105P8F	nudix hydrolase
C3766_08370	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C3766_08375	ENOG4108RMU	ferritin dps family protein
C3766_08385	ENOG4108TU7	Inherit from COG: (ABC) transporter
C3766_08390	ENOG4105CJ1	ABC, transporter
C3766_08415	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C3766_08425	ENOG410900P	UPF0336 protein
C3766_08430	ENOG4105CHR	reductase
C3766_08435	ENOG4105CQB	FAD linked oxidase domain protein
C3766_08445	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
C3766_08450	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
C3766_08460	ENOG4107S21	permease
C3766_08470	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C3766_08500	ENOG4105V75	Transcriptional regulator
C3766_08505	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C3766_08525	ENOG4105CHM	Aminotransferase
C3766_08530	ENOG4105CH7	arginosuccinase
C3766_08535	ENOG4105CDH	Citrulline--aspartate ligase
C3766_08540	ENOG4105DBV	ornithine carbamoyltransferase
C3766_08545	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C3766_08550	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C3766_08555	ENOG4105C8Y	Acetylornithine aminotransferase
C3766_08560	ENOG4105CAS	nag kinase
C3766_08565	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C3766_08570	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C3766_08585	ENOG4105WEF	catalase
C3766_08605	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C3766_08610	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
C3766_08615	ENOG4105F6E	Acyl-transferase
C3766_08630	ENOG4107YTP	response regulator receiver protein
C3766_08635	ENOG4107QIV	Cytochrome c biogenesis protein
C3766_08640	ENOG4105VXM	UPF0154 protein
C3766_08655	ENOG4105VPS	UPF0291 protein
C3766_08660	ENOG4108SVB	resolvase
C3766_08670	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C3766_08725	ENOG4108FKH	Transglycosylase SLT domain
C3766_08765	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C3766_08805	ENOG410682Q	Phage transcriptional regulator, ArpU
C3766_08890	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C3766_08910	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
C3766_08915	ENOG4105C5F	glutamine synthetase
C3766_08920	ENOG4105KV4	Transcriptional regulator
C3766_08925	ENOG410890F	Dynamin family
C3766_08940	ENOG4105C2W	permease
C3766_08955	ENOG4105CTD	carboxy-peptidase
C3766_08960	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C3766_08970	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
C3766_08975	ENOG4106F55	Protein of unknown function (DUF1273)
C3766_08985	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
C3766_08990	ENOG4108I5C	dEAD DEAH box helicase
C3766_08995	ENOG4105VN1	Heat shock protein
C3766_09020	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
C3766_09025	ENOG4105BZ4	penicillin-binding protein
C3766_09030	ENOG4105CSM	endonuclease III
C3766_09040	ENOG4105C5S	asparaginyl-tRNA synthetase
C3766_09055	ENOG4105DVT	helicase
C3766_09060	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C3766_09065	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C3766_09070	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C3766_09085	ENOG4105CPK	Glycosyl transferase (Group 1
C3766_09090	ENOG4105FJR	Lmbe family
C3766_09095	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C3766_09100	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
C3766_09105	ENOG4108JYZ	YitT family
C3766_09130	ENOG4105PE6	Menaquinol-cytochrome c reductase, cytochrome b c subunit
C3766_09135	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C3766_09140	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
C3766_09150	ENOG4108SXZ	UPF0302 protein
C3766_09155	ENOG41068YB	TPR repeat-containing protein
C3766_09165	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C3766_09175	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C3766_09180	ENOG4105KHN	chorismate mutase
C3766_09185	ENOG4105D49	3-dehydroquinate synthase
C3766_09190	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C3766_09195	ENOG4105BZU	Histidine kinase
C3766_09200	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C3766_09205	ENOG4105EAH	synthase
C3766_09210	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C3766_09215	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
C3766_09230	ENOG4105K70	DNA-binding protein
C3766_09235	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
C3766_09255	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C3766_09270	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C3766_09275	ENOG4105CAT	Cytidine monophosphate kinase
C3766_09285	ENOG4105MSI	germination protein ypeb
C3766_09290	ENOG4105F0V	Cell wall hydrolase
C3766_09300	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
C3766_09315	ENOG4107RGJ	metallophosphoesterase
C3766_09330	ENOG4105WEF	catalase
C3766_09345	ENOG4105I7S	Abortive infection protein
C3766_09350	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C3766_09365	ENOG4108SAX	Membrane
C3766_09370	ENOG4105E4C	Lytic transglycosylase catalytic
C3766_09375	ENOG4105BZU	Histidine kinase
C3766_09380	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3766_09385	ENOG4105CRE	cytochrome C
C3766_09390	ENOG4107TWT	Cytochrome c biogenesis protein
C3766_09395	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3766_09400	ENOG4105FE9	pseudouridine synthase
C3766_09410	ENOG4108JIC	nucleoside recognition domain protein
C3766_09415	ENOG4105DZ1	carboxypeptidase
C3766_09420	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C3766_09425	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C3766_09450	ENOG4105G6R	Stage v sporulation protein ae
C3766_09465	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C3766_09475	ENOG41082AN	stage II sporulation protein
C3766_09480	ENOG4105DZ1	carboxypeptidase
C3766_09485	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C3766_09495	ENOG4105I3K	Ferric uptake regulator, Fur family
C3766_09500	ENOG4105MZ9	stage II sporulation protein m
C3766_09520	ENOG4105CPC	Aldo Keto reductase
C3766_09540	ENOG4105CDW	Resistance protein
C3766_09550	ENOG4105VRS	hydrolase family 18
C3766_09560	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C3766_09565	ENOG4108IXY	short-chain dehydrogenase reductase
C3766_09575	ENOG4105II7	pyrroline-5-carboxylate reductase
C3766_09580	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
C3766_09585	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C3766_09590	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C3766_09600	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C3766_09610	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
C3766_09615	ENOG4108Y6J	UPF0403 protein
C3766_09620	ENOG4105DE4	1-phosphofructokinase
C3766_09625	ENOG4105C7S	Dehydrogenase
C3766_09630	ENOG4105CPP	Dehydrogenase, E1 component
C3766_09645	ENOG4107RDP	Dehydrogenase
C3766_09650	ENOG4108JUB	Transcriptional regulator
C3766_09660	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C3766_09665	ENOG4107QQR	Sporulation
C3766_09675	ENOG4105S1Z	Stage IV sporulation protein B
C3766_09680	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C3766_09685	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C3766_09690	ENOG4105DX0	Hemolysin A
C3766_09695	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C3766_09710	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C3766_09720	ENOG4105M7K	Involved in the transcription termination process (By similarity)
C3766_09725	ENOG4108ZSR	alkaline shock protein
C3766_09730	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C3766_09750	ENOG410644B	Stage III sporulation protein af
C3766_09760	ENOG4105KQ4	Stage iii sporulation protein ad
C3766_09765	ENOG4108CQH	stage III sporulation protein AC
C3766_09770	ENOG4105KR5	Stage iii sporulation protein
C3766_09775	ENOG4105CD2	stage iii sporulation protein aa
C3766_09780	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C3766_09785	ENOG4105DC7	peptidase M24
C3766_09790	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C3766_09800	ENOG4105CBJ	Metal-dependent enzyme
C3766_09815	ENOG4105EA8	2-Nitropropane dioxygenase
C3766_09820	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
C3766_09825	ENOG4105CHU	acetyl-coa acetyltransferase
C3766_09830	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C3766_09835	ENOG4105C26	Dehydrogenase
C3766_09840	ENOG4108UKI	Enoyl-CoA hydratase
C3766_09875	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
C3766_09880	ENOG4105DZS	Phenylacetate-CoA ligase
C3766_09885	ENOG4108Z4U	Ferredoxin
C3766_09890	ENOG4105CAY	ferredoxin--nadp reductase
C3766_09900	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C3766_09905	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
C3766_09910	ENOG4105WZW	rhodanese family
C3766_09915	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C3766_09925	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C3766_09930	ENOG4105C0D	helicase
C3766_09945	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C3766_09970	ENOG4106855	Competence protein
C3766_09995	ENOG4105C5X	domain protein
C3766_10005	ENOG4105DKQ	ROK family
C3766_10015	ENOG4107ZXI	Rhomboid family
C3766_10025	ENOG4105WDJ	50S ribosomal protein L33
C3766_10035	ENOG4107RF6	penicillin-binding protein
C3766_10045	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C3766_10055	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C3766_10060	ENOG4108U5J	'-nucleotidase
C3766_10065	ENOG4105N80	Ferric uptake regulator, Fur family
C3766_10070	ENOG4105FAV	ABC, transporter
C3766_10075	ENOG4105FDK	ABC transporter
C3766_10090	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
C3766_10105	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C3766_10110	ENOG4105EGD	dinuclear metal center protein, YbgI family
C3766_10130	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C3766_10135	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C3766_10140	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C3766_10155	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
C3766_10165	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C3766_10170	ENOG4107YR5	Diacylglycerol kinase
C3766_10175	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C3766_10180	ENOG4105CTJ	Metal Dependent Phosphohydrolase
C3766_10185	ENOG4105C9A	Phoh family
C3766_10195	ENOG41068P3	sporulation protein YqfC
C3766_10200	ENOG4105KTH	gatB Yqey
C3766_10205	ENOG4105VCC	30S ribosomal protein S21
C3766_10210	ENOG410855V	Acylphosphatase
C3766_10220	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C3766_10225	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C3766_10230	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C3766_10235	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C3766_10240	ENOG4105CFG	Acts as a chaperone (By similarity)
C3766_10245	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C3766_10255	ENOG4105CSA	Coproporphyrinogen iii oxidase
C3766_10260	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C3766_10265	ENOG4108ZRV	stage ii sporulation protein p
C3766_10270	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
C3766_10275	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C3766_10280	ENOG4105TQK	DNA polymerase iii, delta' subunit
C3766_10295	ENOG4108UK2	deaminase
C3766_10300	ENOG4105KQC	Competence protein
C3766_10310	ENOG4105DXX	methyltransferase
C3766_10320	ENOG4108WF2	Metal Dependent Phosphohydrolase
C3766_10325	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C3766_10330	ENOG410812S	Rna-binding protein
C3766_10335	ENOG4105E2X	shikimate dehydrogenase
C3766_10340	ENOG4105CQW	ribosome biogenesis GTPase YqeH
C3766_10345	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
C3766_10350	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C3766_10355	ENOG4105CQB	FAD linked oxidase domain protein
C3766_10365	ENOG4107STQ	Multicopper oxidase
C3766_10370	ENOG4107Y70	Heat shock protein
C3766_10375	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
C3766_10390	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C3766_10405	ENOG4107STQ	Multicopper oxidase
C3766_10410	ENOG4107Y70	Heat shock protein
C3766_10440	ENOG4108V0P	LemA family
C3766_10450	ENOG4105WMR	Protein CrcB homolog
C3766_10460	ENOG4105PGM	cation diffusion facilitator family transporter
C3766_10470	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C3766_10475	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C3766_10480	ENOG4108JU3	Alkyl hydroperoxide reductase
C3766_10485	ENOG4105D3R	alkyl hydroperoxide reductase
C3766_10515	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C3766_10520	ENOG4105DBI	uridine monophosphokinase
C3766_10525	ENOG4108VQJ	O-methyltransferase
C3766_10530	ENOG4105HHA	aminodeoxychorismate lyase
C3766_10535	ENOG4105VPH	UPF0473 protein
C3766_10540	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C3766_10545	ENOG4105VBH	UPF0297 protein
C3766_10550	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C3766_10555	ENOG4105C02	permease
C3766_10565	ENOG41060CR	
C3766_10585	ENOG4105C7H	Helicase, RecD TraA family
C3766_10595	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C3766_10600	ENOG4105C3J	Cysteine desulfurase
C3766_10620	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C3766_10625	ENOG4105D1H	recombination factor protein RarA
C3766_10630	ENOG4105CUZ	uba thif-type nad fad binding protein
C3766_10645	ENOG4105C9M	aspartyl-trna synthetase
C3766_10650	ENOG4105CUT	histidyl-tRNA synthetase
C3766_10655	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C3766_10660	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3766_10665	ENOG4105CW7	secretion protein, HlyD family
C3766_10670	ENOG410834F	Transcriptional regulator
C3766_10675	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C3766_10685	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C3766_10690	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C3766_10695	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C3766_10705	ENOG4105CKP	Polysaccharide Biosynthesis Protein
C3766_10710	ENOG4108QG2	Membrane
C3766_10720	ENOG4105VIE	preprotein translocase, subunit YajC
C3766_10725	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C3766_10730	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C3766_10735	ENOG41061AI	Protein of unknown function (DUF2905)
C3766_10745	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C3766_10760	ENOG4105CDY	transcriptional regulatory protein
C3766_10770	ENOG4106678	morphogenetic protein associated with SpoVID
C3766_10780	ENOG4105CQC	Prephenate dehydratase
C3766_10785	ENOG41090I5	UPF0735 ACT domain-containing protein
C3766_10790	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C3766_10800	ENOG4105K46	50S ribosomal protein l27
C3766_10805	ENOG4105X36	(ribosomal) protein
C3766_10810	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C3766_10815	ENOG4105C03	ribonuclease
C3766_10830	ENOG4107QMS	site-determining protein
C3766_10835	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
C3766_10845	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C3766_10850	ENOG4105DFF	Rod shape-determining protein mreb
C3766_10855	ENOG4105W5Q	DNA repair protein (RadC
C3766_10875	ENOG4106A3R	peptidase
C3766_10900	ENOG4105D7Q	type ii secretion system
C3766_10905	ENOG4105CZX	twitching motility protein
C3766_10910	ENOG4107QHF	type ii secretion system protein e
C3766_10945	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C3766_10950	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C3766_10960	ENOG4106AR7	Spore coat protein
C3766_10965	ENOG41068KH	stage VI sporulation protein D
C3766_10965	ENOG41068KH	stage VI sporulation protein D
C3766_10970	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C3766_10975	ENOG4105D52	delta-aminolevulinic acid dehydratase
C3766_10990	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C3766_11000	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C3766_11010	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C3766_11015	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C3766_11020	ENOG4108IUQ	atp-dependent protease
C3766_11025	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C3766_11030	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C3766_11060	ENOG4105M59	Phosphodiesterase, mj0936 family
C3766_11065	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C3766_11070	ENOG4108XJQ	germination protein
C3766_11085	ENOG4105E2A	Dehydrogenase
C3766_11105	ENOG41067TZ	transcriptional regulator, MarR family
C3766_11135	ENOG4105PFC	Transcriptional regulator
C3766_11145	ENOG4105E33	succinate dehydrogenase
C3766_11155	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
C3766_11170	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C3766_11175	ENOG4105K63	Thioredoxin
C3766_11180	ENOG4105C10	Electron transfer flavoprotein
C3766_11185	ENOG4105BZJ	Electron transfer flavoprotein
C3766_11190	ENOG41060WC	Enoyl-CoA hydratase
C3766_11195	ENOG4107Z3H	Transcriptional regulator, TetR family
C3766_11200	ENOG4105CEY	Amp-dependent synthetase and ligase
C3766_11205	ENOG4105C98	muts2 protein
C3766_11210	ENOG4105DCG	PHP domain protein
C3766_11220	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
C3766_11230	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C3766_11235	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C3766_11240	ENOG4108RWN	rrna methyltransferase
C3766_11245	ENOG41067MF	small acid-soluble spore protein
C3766_11275	ENOG4105Z26	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
C3766_11300	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C3766_11310	ENOG4108YYH	Nadph-dependent fmn reductase
C3766_11315	ENOG4107SDU	Methyl-accepting chemotaxis
C3766_11335	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C3766_11340	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C3766_11345	ENOG4105VJV	50s ribosomal protein L35
C3766_11350	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C3766_11360	ENOG4105C22	threonyL-tRNA synthetase
C3766_11365	ENOG4108TDW	sporulation protein YtxC
C3766_11380	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C3766_11385	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C3766_11390	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C3766_11400	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C3766_11405	ENOG4105C2M	dna polymerase I
C3766_11410	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C3766_11415	ENOG4108HMX	isocitrate dehydrogenase (NADP)
C3766_11420	ENOG4105BZN	citrate synthase
C3766_11425	ENOG4108VMM	UPF0756 membrane protein
C3766_11430	ENOG4108REF	Sporulation integral membrane protein ytvi
C3766_11440	ENOG4105CTQ	phosphohexokinase
C3766_11445	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C3766_11450	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C3766_11455	ENOG4105C6K	Malic enzyme
C3766_11460	ENOG4105C0B	DNA polymerase III (alpha subunit)
C3766_11475	ENOG4105SFS	phosphoesterase RecJ domain protein
C3766_11490	ENOG4105E8R	UPF0173 metal-dependent hydrolase
C3766_11505	ENOG4107YZX	Universal stress protein
C3766_11515	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C3766_11525	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
C3766_11530	ENOG4105KBJ	sporulation protein ytfj
C3766_11540	ENOG4105VK3	rdd domain containing protein
C3766_11545	ENOG4105D07	Signal peptide peptidase, SppA
C3766_11550	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C3766_11555	ENOG4105YWU	small acid-soluble spore protein
C3766_11560	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
C3766_11570	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
C3766_11575	ENOG4105U5Y	Transcriptional regulator
C3766_11585	ENOG4105BZU	Histidine kinase
C3766_11590	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C3766_11610	ENOG4105C26	Dehydrogenase
C3766_11615	ENOG4108JUB	Transcriptional regulator
C3766_11630	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C3766_11640	ENOG4108JB9	formate dehydrogenase
C3766_11650	ENOG4105D06	uba thif-type nad fad binding protein
C3766_11655	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C3766_11660	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
C3766_11665	ENOG4108ZAF	Molybdopterin
C3766_11670	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
C3766_11675	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C3766_11685	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
C3766_11690	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C3766_11700	ENOG4105E0C	molybdate abc transporter
C3766_11705	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C3766_11715	ENOG4105F1V	Acetoin utilization protein
C3766_11720	ENOG4105W87	Cbs domain
C3766_11725	ENOG4105DGU	Histone deacetylase
C3766_11730	ENOG4105ETE	Transcriptional regulator (LacI family
C3766_11735	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C3766_11750	ENOG4105DFU	Cell wall formation (By similarity)
C3766_11765	ENOG4108VDD	TRNA binding domain protein
C3766_11770	ENOG4108NKM	UPF0354 protein
C3766_11780	ENOG4108MJI	response regulator
C3766_11785	ENOG4105BZU	Histidine kinase
C3766_11795	ENOG4105BZU	Histidine kinase
C3766_11835	ENOG4105C8F	Beta-lactamase domain protein
C3766_11840	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C3766_11850	ENOG4108V15	phosphotransferase enzyme family
C3766_11875	ENOG4107QSE	Dipeptidase
C3766_11885	ENOG4105YW5	deoR family transcriptional regulator
C3766_11910	ENOG4105C8T	Leucyl-tRNA synthetase
C3766_11915	ENOG410605W	Major Facilitator
C3766_11930	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C3766_11945	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
C3766_11950	ENOG4108Z0R	Transferase
C3766_11955	ENOG4105CAQ	asparagine synthetase
C3766_11960	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C3766_11980	ENOG4108WS4	fmn reductase
C3766_11990	ENOG4105CMG	Carbohydrate kinase
C3766_12025	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
C3766_12040	ENOG4108RMU	ferritin dps family protein
C3766_12045	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C3766_12055	ENOG4105DSE	periplasmic solute binding protein
C3766_12065	ENOG4105DTQ	mandelate racemase muconate lactonizing
C3766_12075	ENOG4108IPT	Naphthoate synthase
C3766_12080	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
C3766_12085	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C3766_12090	ENOG4105E4F	Isochorismate synthase
C3766_12095	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
C3766_12225	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3766_12250	ENOG4105KT7	mgtC SapB transporter
C3766_12265	ENOG4105C59	p-type ATPase
C3766_12270	ENOG410681U	heavy metal transport detoxification protein
C3766_12305	ENOG4105XTG	Pfam:DUF156
C3766_12330	ENOG4106CAD	Protein of unknown function (DUF3311)
C3766_12335	ENOG4105E1V	na solute symporter
C3766_12360	ENOG4105BZU	Histidine kinase
C3766_12365	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3766_12370	ENOG41090UD	(LipO)protein
C3766_12375	ENOG4107GJV	short-chain dehydrogenase reductase
C3766_12385	ENOG4107VMI	polysaccharide deacetylase
C3766_12410	ENOG4105VFE	sira family
C3766_12415	ENOG4105XTG	Pfam:DUF156
C3766_12420	ENOG4107Y9E	nuclease
C3766_12425	ENOG4105C5Y	PTS System
C3766_12445	ENOG4107QNK	)-transporter
C3766_12450	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
C3766_12455	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
C3766_12460	ENOG4105CMD	Transcriptional regulator, GntR family
C3766_12485	ENOG4108HWW	ABC transporter
C3766_12490	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
C3766_12500	ENOG4105CMD	Transcriptional regulator, GntR family
C3766_12505	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
C3766_12520	ENOG4105CHR	reductase
C3766_12540	ENOG4105C26	Dehydrogenase
C3766_12560	ENOG4107PBV	potassium channel
C3766_12570	ENOG4105WG9	Conserved Protein
C3766_12600	ENOG4105CV8	reductase
C3766_12620	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C3766_12625	ENOG4105Y38	Kinase-associated protein B
C3766_12650	ENOG4105KA0	thioesterase Superfamily protein
C3766_12680	ENOG4105E1K	spore germination protein
C3766_12690	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C3766_12695	ENOG41069ER	domain protein
C3766_12705	ENOG4105CEP	NADH dehydrogenase
C3766_12710	ENOG4105CAY	ferredoxin--nadp reductase
C3766_12735	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C3766_12745	ENOG41083MR	nifu domain-containing protein
C3766_12760	ENOG4108W5N	phosphatidylglycerophosphatase a
C3766_12765	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
C3766_12775	ENOG4105MMD	transcriptional regulator
C3766_12780	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C3766_12785	ENOG4105FAA	peptidase M23
C3766_12790	ENOG4108YTE	sporulation protein YunB
C3766_12795	ENOG4105KZD	Domain of unknown function (DUF1805)
C3766_12800	ENOG4107R8B	5'-nucleotidase
C3766_12805	ENOG4105DIW	FeS assembly protein SUFB
C3766_12810	ENOG4108UNV	SUF system FeS assembly protein, NifU family
C3766_12820	ENOG4105JRK	feS assembly protein SufD
C3766_12825	ENOG4105C3K	feS assembly ATPase SufC
C3766_12845	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C3766_12850	ENOG41080E8	Transcriptional regulator, Spx MgsR family
C3766_12855	ENOG4105C1G	acyl-Coa dehydrogenase
C3766_12860	ENOG4105CHU	acetyl-coa acetyltransferase
C3766_12890	ENOG4105SZ6	Thioredoxin
C3766_12920	ENOG4105BZU	Histidine kinase
C3766_12925	ENOG4105CH6	catalase
C3766_12930	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
C3766_12940	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
C3766_12960	ENOG4105EMN	RNA polymerase sigma factor
C3766_12980	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C3766_12990	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
C3766_12995	ENOG4105CHR	reductase
C3766_13000	ENOG4105CT4	transporter
C3766_13005	ENOG4105D2H	Uronic isomerase
C3766_13010	ENOG4105CTX	dehydratase
C3766_13015	ENOG4107QZW	Altronate oxidoreductase
C3766_13025	ENOG4108UHU	Aldolase
C3766_13030	ENOG4107HP6	Transcriptional regulator
C3766_13090	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C3766_13095	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C3766_13105	ENOG4105XZU	Preprotein translocase, subunit SecG
C3766_13110	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C3766_13115	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C3766_13125	ENOG4105BZA	Phosphoglycerate kinase
C3766_13145	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C3766_13195	ENOG4105BZ4	penicillin-binding protein
C3766_13210	ENOG4108JQ7	(ABC) transporter
C3766_13215	ENOG4107SN7	NLP P60 protein
C3766_13225	ENOG4105C3U	ABC transporter
C3766_13230	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C3766_13235	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C3766_13240	ENOG4108Z86	Glutamine amidotransferase
C3766_13250	ENOG4105D7N	magnesium and cobalt transport protein CorA
C3766_13265	ENOG4105ED1	spovr family
C3766_13270	ENOG4108TGC	Acyltransferase
C3766_13295	ENOG4107GRR	phosphate transport regulator
C3766_13300	ENOG4105CJ3	phosphate transporter
C3766_13315	ENOG4106AKX	UPF0229 protein
C3766_13325	ENOG4105CYN	Serine protein kinase
C3766_13340	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C3766_13350	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C3766_13355	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
C3766_13375	ENOG4107WD4	Releases the N-terminal proline from various substrates (By similarity)
C3766_13385	ENOG4105DRP	amino acid AbC transporter
C3766_13390	ENOG4105CDA	abc transporter atp-binding protein
C3766_13395	ENOG4108QTI	)-transporter
C3766_13405	ENOG4105C6N	Formate acetyltransferase
C3766_13410	ENOG4105F1A	Pyruvate formate-lyase
C3766_13415	ENOG4107V0Z	fmn reductase
C3766_13430	ENOG4105CJ1	ABC, transporter
C3766_13465	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3766_13480	ENOG4105X71	Membrane
C3766_13490	ENOG4105FDP	GntR family transcriptional regulator
C3766_13495	ENOG4105DUX	Transporter
C3766_13500	ENOG4107VFR	oxidoreductase
C3766_13505	ENOG4108M15	ABC transporter
C3766_13510	ENOG4108IUW	ABC transporter
C3766_13530	ENOG41067TZ	transcriptional regulator, MarR family
C3766_13550	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C3766_13575	ENOG4105D2S	major facilitator superfamily
C3766_13600	ENOG4105DEN	Luciferase family
C3766_13705	ENOG4105TUA	UPF0295 protein
C3766_13710	ENOG4107FQX	Alpha-acetolactate decarboxylase
C3766_13720	ENOG4107RSM	transcriptional regulator
C3766_13725	ENOG4105IJS	Transcriptional regulator
C3766_13730	ENOG4105C5B	carbamate kinase
C3766_13740	ENOG4105DBV	ornithine carbamoyltransferase
C3766_13750	ENOG4105G5W	regulator Fur family
C3766_13765	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C3766_13770	ENOG4105GVF	(ABC) transporter
C3766_13775	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C3766_13780	ENOG4105E2Y	ABC, transporter
C3766_13790	ENOG4107RCC	Major Facilitator Superfamily
C3766_13815	ENOG4105C5Y	PTS System
C3766_13820	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C3766_13835	ENOG4105EVI	UPF0374 protein
C3766_13850	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
C3766_13855	ENOG4105C5Q	Transcriptional regulator
C3766_13860	ENOG4105CBC	glutamate synthase
C3766_13865	ENOG4105BZ8	glutamate synthase
C3766_13880	ENOG4105CJ1	ABC, transporter
C3766_13890	ENOG4105XHU	Acid-soluble spore protein K
C3766_13895	ENOG41067AE	Membrane-bound metal-dependent hydrolase
C3766_13900	ENOG4105CEN	a g-specific adenine glycosylase
C3766_13920	ENOG410902V	Modulates RecA activity (By similarity)
C3766_13935	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C3766_13945	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C3766_13950	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C3766_13955	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C3766_13960	ENOG4105DDQ	anthranilate synthase
C3766_13965	ENOG4105CRQ	synthase (Component I)
C3766_13970	ENOG4107RBB	ABC transporter, permease
C3766_13980	ENOG410624X	efflux transporter, rnd family, mfp subunit
C3766_14000	ENOG4105CJ1	ABC, transporter
C3766_14040	ENOG4108Q9V	regulatoR
C3766_14045	ENOG4105BZU	Histidine kinase
C3766_14055	ENOG4105C26	Dehydrogenase
C3766_14055	ENOG4105C26	Dehydrogenase
C3766_14070	ENOG4105C8Q	Methyl-accepting chemotaxis
C3766_14075	ENOG4105C5I	Dehydrogenase
C3766_14080	ENOG4105C5R	Aminotransferase
C3766_14085	ENOG4108JQ1	Dehydrogenase
C3766_14100	ENOG4105C7B	Threonine dehydratase
C3766_14105	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C3766_14110	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C3766_14115	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C3766_14120	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C3766_14125	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C3766_14130	ENOG4108ZP8	Acetolactate synthase small subunit
C3766_14135	ENOG4105C7K	acetolactate synthase
C3766_14140	ENOG4105C01	Dihydroxy-acid dehydratase
C3766_14170	ENOG4107E6A	Cytochrome p-450
C3766_14175	ENOG4106I4J	membrane
C3766_14185	ENOG4105FCD	Major Facilitator
C3766_14190	ENOG4105DY9	regulatoR
C3766_14195	ENOG4108HRK	Histidine kinase
C3766_14200	ENOG4105HDK	L-asparaginase
C3766_14205	ENOG4107STQ	Multicopper oxidase
C3766_14215	ENOG4105ECB	domain protein
C3766_14250	ENOG4105EC8	Methyl-accepting chemotaxis
C3766_14255	ENOG4105NX3	Membrane
C3766_14260	ENOG4105VMP	Transcriptional regulator
C3766_14275	ENOG4107R6U	sodium dicarboxylate symporter
C3766_14280	ENOG4105SXS	Protein of unknown function (DUF456)
C3766_14300	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C3766_14305	ENOG4105CSH	Transporter
C3766_14320	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C3766_14325	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C3766_14330	ENOG4105C8Q	Methyl-accepting chemotaxis
C3766_14350	ENOG4105D1H	recombination factor protein RarA
C3766_14355	ENOG4105BZ1	(ABC) transporter
C3766_14360	ENOG4105FS7	Transcriptional regulator
C3766_14370	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C3766_14395	ENOG4105UPD	Calcium Proton
C3766_14400	ENOG4108ISG	Major Facilitator
C3766_14405	ENOG4107U9T	Pfam:Ribonuclease_BN
C3766_14410	ENOG41068PA	UPF0435 protein
C3766_14415	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C3766_14420	ENOG4107RKG	DJ-1/PfpI family
C3766_14425	ENOG4105ER2	Ompa motb domain protein
C3766_14430	ENOG4105E14	MotA TolQ exbB proton channel
C3766_14440	ENOG4105K78	MarR family Transcriptional regulator
C3766_14455	ENOG4108S4H	thioesterase Superfamily protein
C3766_14465	ENOG4105DZ6	Band 7 protein
C3766_14475	ENOG4105C28	cystathionine
C3766_14485	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
C3766_14490	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
C3766_14495	ENOG4108V2W	Carbonate dehydratase
C3766_14500	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C3766_14540	ENOG4105PTM	secreted protein
C3766_14545	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
C3766_14555	ENOG4105CVJ	phosphoglycerate mutase
C3766_14560	ENOG41067QW	Transcriptional regulator
C3766_14565	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
C3766_14570	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
C3766_14590	ENOG4105FB9	CRISPR-associated protein
C3766_14630	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C3766_14635	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
C3766_14645	ENOG4107SUZ	Sodium/hydrogen exchanger family
C3766_14650	ENOG4105DM4	PTS System
C3766_14655	ENOG4105E98	transcriptional regulator DeoR family
C3766_14660	ENOG4105DCT	glycerol dehydrogenase
C3766_14675	ENOG410667J	hydrolase
C3766_14685	ENOG4105C5Y	PTS System
C3766_14690	ENOG4107QNK	)-transporter
C3766_14695	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C3766_14715	ENOG4108JPW	Aminotransferase
C3766_14725	ENOG4105VDH	Dihydroxyacetone kinase
C3766_14730	ENOG4108UTZ	Dihydroxyacetone kinase
C3766_14735	ENOG4105CMT	Dihydroxyacetone kinase
C3766_14750	ENOG4108DBC	nitroreductase
C3766_14760	ENOG410635A	Membrane
C3766_14785	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C3766_14810	ENOG4107QX3	carboxylase
C3766_14815	ENOG4105E39	Enoyl-CoA hydratase
C3766_14825	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C3766_14830	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
C3766_14835	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C3766_14840	ENOG4105C1G	acyl-Coa dehydrogenase
C3766_14845	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C3766_14860	ENOG4105C8Y	Acetylornithine aminotransferase
C3766_14865	ENOG4108JUB	Transcriptional regulator
C3766_14885	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
C3766_14895	ENOG4108IQI	permease
C3766_14900	ENOG4105EJ2	Transcriptional regulator
C3766_14955	ENOG4105WYW	fructose-bisphosphate aldolase
C3766_14975	ENOG4105C84	Histidine ammonia-lyase
C3766_14985	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C3766_14990	ENOG4105CI2	imidazolone-5-propionate hydrolase
C3766_14995	ENOG4105CGP	Urocanate hydratase
C3766_15000	ENOG4105D2X	ABC transporter substrate-binding protein
C3766_15005	ENOG4105C5I	Dehydrogenase
C3766_15020	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C3766_15040	ENOG4105CNN	ABC, transporter
C3766_15070	ENOG4107SQC	5-methylcytosine-specific restriction enzyme subunit McrC
C3766_15075	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
C3766_15080	ENOG4105DZR	Type I site-specific deoxyribonuclease
C3766_15110	ENOG4108V06	Glutathione peroxidase
C3766_15115	ENOG4105C5Y	PTS System
C3766_15140	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C3766_15205	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
C3766_15225	ENOG4105BZW	Glycerate kinase
C3766_15230	ENOG4107QQ0	gntp family
C3766_15235	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C3766_15240	ENOG4105CNN	ABC, transporter
C3766_15245	ENOG4105C2J	ABC transporter
C3766_15250	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
C3766_15255	ENOG4108RVA	ribokinase
C3766_15260	ENOG4105ETE	Transcriptional regulator (LacI family
C3766_15300	ENOG4105KTB	nuclear export factor GLE1
C3766_15305	ENOG4108T5E	Copper resistance protein
C3766_15315	ENOG4105DJV	ribulose-phosphate 3-epimerase
C3766_15320	ENOG4105ETE	Transcriptional regulator (LacI family
C3766_15335	ENOG4105BZU	Histidine kinase
C3766_15340	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C3766_15345	ENOG4105VEQ	Cold shock protein
C3766_15355	ENOG4107Y9U	Membrane
C3766_15370	ENOG4105QYV	Membrane
C3766_15375	ENOG4105D17	glycoside hydrolase, family 3 domain protein
C3766_15385	ENOG4105EHZ	conserved protein UCP016719
C3766_15400	ENOG4105BZ1	(ABC) transporter
C3766_15405	ENOG4105BZ1	(ABC) transporter
C3766_15425	ENOG4105K4H	Nlp p60 protein
C3766_15445	ENOG4105EBR	Carboxylesterase
C3766_15450	ENOG4105EUF	amidase EC 3.5.1.4
C3766_15455	ENOG4107QNK	)-transporter
C3766_15460	ENOG4105C26	Dehydrogenase
C3766_15500	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C3766_15510	ENOG4108UZX	fmn reductase
C3766_15515	ENOG4105E2Y	ABC, transporter
C3766_15520	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C3766_15525	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
C3766_15530	ENOG4105GVF	(ABC) transporter
C3766_15555	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C3766_15565	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C3766_15570	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
C3766_15580	ENOG4107RHR	regulatoR
C3766_15600	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
C3766_15615	ENOG4105E7W	lamb ycsf family protein
C3766_15625	ENOG4105P4J	Allophanate hydrolase, subunit 1
C3766_15630	ENOG4105CZM	Major Facilitator
C3766_15635	ENOG4108X3M	OsmC Ohr family protein
C3766_15640	ENOG4105CDA	abc transporter atp-binding protein
C3766_15645	ENOG4105E5Q	amino acid AbC transporter
C3766_15650	ENOG4108HW3	(ABC) transporter
C3766_15660	ENOG4105C28	cystathionine
C3766_15680	ENOG4108UHU	Aldolase
C3766_15705	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C3766_15730	ENOG4107VFR	oxidoreductase
C3766_15775	ENOG4105CHR	reductase
C3766_15810	ENOG4105F3R	pts system mannose fructose sorbose family iid
C3766_15885	ENOG4105CK7	Sodium proline symporter
C3766_15890	ENOG4105CBD	Diacylglycerol kinase
C3766_15920	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C3766_15925	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C3766_15930	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C3766_15940	ENOG4107QP3	malate synthase g
C3766_15955	ENOG4105C4R	Atp-dependent dna helicase
C3766_15960	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
C3766_15965	ENOG4105KGF	protein, YerC YecD
C3766_15970	ENOG4108R5T	secreted protein
C3766_15985	ENOG4105C12	Phosphoribosylglycinamide synthetase
C3766_15995	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C3766_16000	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C3766_16005	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C3766_16015	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C3766_16020	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C3766_16025	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
C3766_16035	ENOG4105C83	adenylosuccinate lyase
C3766_16040	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C3766_16045	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C3766_16060	ENOG4107ZXU	DSBA oxidoreductase
C3766_16065	ENOG4105CI1	PTS System
C3766_16080	ENOG4105CI1	PTS System
C3766_16105	ENOG4105CK2	sodium dicarboxylate symporter
C3766_16115	ENOG4105CID	antiterminator
C3766_16120	ENOG4105C7N	Xanthine uracil vitamin C permease
C3766_16130	ENOG4105BZ1	(ABC) transporter
C3766_16135	ENOG4105D94	Major Facilitator Superfamily
C3766_16140	ENOG4105WH1	Two component transcriptional regulator luxr family
C3766_16145	ENOG4105BZU	Histidine kinase
C3766_16150	ENOG4105CJ1	ABC, transporter
C3766_16160	ENOG4108KYE	ABC-2 type transporter
C3766_16175	ENOG4105ERH	Fumarylacetoacetate hydrolase
C3766_16195	ENOG41082UD	thioesterase Superfamily protein
C3766_16200	ENOG4105CEY	Amp-dependent synthetase and ligase
C3766_16205	ENOG4105CHU	acetyl-coa acetyltransferase
C3766_16210	ENOG4105E39	Enoyl-CoA hydratase
C3766_16215	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C3766_16225	ENOG4105D2S	major facilitator superfamily
C3766_16235	ENOG4105ERH	Fumarylacetoacetate hydrolase
C3766_16245	ENOG4107QPK	)-transporter
C3766_16275	ENOG4105CZV	ABC transporter
C3766_16280	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
C3766_16285	ENOG4105U3E	Transcriptional regulator
C3766_16290	ENOG4105PY6	Phenolic acid decarboxylase
C3766_16295	ENOG4108RYK	Nad-dependent epimerase dehydratase
C3766_16300	ENOG4108Z40	Transcriptional regulator
C3766_16345	ENOG4105CUC	YeeE YedE family protein
C3766_16350	ENOG4107QKS	N-acylglucosamine 2-epimerase
C3766_16355	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C3766_16375	ENOG4105E0A	ABC, transporter
C3766_16380	ENOG4105EHG	Permease protein
C3766_16415	ENOG41067QW	Transcriptional regulator
C3766_16430	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C3766_16435	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
C3766_16440	ENOG4105DAP	Nicotinate phosphoribosyltransferase
C3766_16450	ENOG4105DTQ	mandelate racemase muconate lactonizing
C3766_16470	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C3766_16475	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C3766_16480	ENOG4108TYN	CAAX amino terminal protease family protein
C3766_16490	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C3766_16495	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
C3766_16500	ENOG4105C5H	ABC transporter
C3766_16510	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C3766_16515	ENOG410801F	ribosomal-protein-alanine acetyltransferase
C3766_16520	ENOG41072GX	Peptidase M22 Glycoprotease
C3766_16525	ENOG4105K8N	protein family UPF0079, ATPase
C3766_16610	ENOG410906U	SprT-like
C3766_16625	ENOG41064BQ	Phosphatase
C3766_16635	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
C3766_16640	ENOG4105WN5	stage II sporulation protein
C3766_16645	ENOG4107SGM	protein serine threonine phosphatase
C3766_16650	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
C3766_16655	ENOG4105FUA	antagonist
C3766_16660	ENOG4107MMM	Anti-sigma-factor antagonist
C3766_16670	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
C3766_16685	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
C3766_16690	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C3766_16700	ENOG4105C1J	atp-dependent rna helicase
C3766_16735	ENOG4107URF	beta-phospho-glucomutase
C3766_16740	ENOG4105FKQ	transcriptional regulator
C3766_16745	ENOG4105CG3	alpha amylase, catalytic region
C3766_16750	ENOG4108IUK	alpha amylase, catalytic
C3766_16755	ENOG4107FKK	extracellular solute-binding protein family 1
C3766_16760	ENOG4105D56	permease protein
C3766_16765	ENOG4105EG2	ABC transporter, permease
C3766_16780	ENOG4105CG3	alpha amylase, catalytic region
C3766_16785	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
C3766_16790	ENOG4105CPF	Cell wall formation (By similarity)
C3766_16805	ENOG4105C37	(CBS) domain
C3766_16815	ENOG4105C37	(CBS) domain
C3766_16830	ENOG4105C0D	helicase
C3766_16845	ENOG4105Z8H	single-stranded DNA-binding protein
C3766_16850	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C3766_16855	ENOG4105CGA	flagellar basal-body rod protein FlgG
C3766_16870	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
C3766_16875	ENOG4105FRN	stage II sporulation protein
C3766_16890	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C3766_16900	ENOG4106778	Protein of unknown function (DUF1146)
C3766_16905	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C3766_16910	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C3766_16915	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C3766_16920	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C3766_16925	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C3766_16935	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C3766_16940	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
C3766_16945	ENOG41062M3	atp synthase
C3766_16950	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C3766_16960	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C3766_16970	ENOG4108YZG	isomerase
C3766_16980	ENOG4108W2P	Methyl-accepting chemotaxis
C3766_16990	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
C3766_16995	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C3766_17000	ENOG4108ZXQ	stage ii sporulation protein r
C3766_17005	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C3766_17010	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C3766_17020	ENOG4107104	thymidine kinase
C3766_17025	ENOG41082DI	50s ribosomal protein l31
C3766_17035	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C3766_17040	ENOG4105CBT	Fructose-1,6-bisphosphatase
C3766_17045	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C3766_17050	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C3766_17055	ENOG4105D2N	Aldolase
C3766_17060	ENOG410812K	response regulator receiver protein
C3766_17075	ENOG4105CZV	ABC transporter
C3766_17080	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
C3766_17085	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C3766_17110	ENOG4105C19	ABC transporter
C3766_17135	ENOG4105D5P	Methylmalonyl-coA mutase
C3766_17140	ENOG4107Z3H	Transcriptional regulator, TetR family
C3766_17145	ENOG4105C1G	acyl-Coa dehydrogenase
C3766_17150	ENOG4105C1G	acyl-Coa dehydrogenase
C3766_17160	ENOG4105DF6	Fe-S oxidoreductase
C3766_17170	ENOG4105C75	arginyL-tRNA synthetase
C3766_17180	ENOG4105CYW	agmatinase
C3766_17185	ENOG4105BZ4	penicillin-binding protein
C3766_17190	ENOG4108XFG	YwhD family
C3766_17195	ENOG4108Z4T	Peptidase M50
C3766_17200	ENOG41069HH	4-oxalocrotonate tautomerase
C3766_17210	ENOG4105DCI	Phosphohydrolase
C3766_17215	ENOG4108VCI	transcription factor, rsfa family
C3766_17225	ENOG4108IJ2	phosphate acetyltransferase
C3766_17230	ENOG4107JTW	chlorite dismutase
C3766_17250	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C3766_17280	ENOG4108IUW	ABC transporter
C3766_17295	ENOG4108JJB	ABC transporter
C3766_17320	ENOG4105DWF	phosphomethylpyrimidine kinase
C3766_17330	ENOG4107YEI	lmbE family
C3766_17335	ENOG410667J	hydrolase
C3766_17340	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C3766_17345	ENOG4105G6Z	alkaline phosphatase
C3766_17350	ENOG4106KNT	transcriptional regulator
C3766_17360	ENOG4108Z66	YbaK ebsC protein
C3766_17365	ENOG41067MG	lrgb family
C3766_17370	ENOG4105VAW	lrga family
C3766_17375	ENOG4105CMU	LysR family (Transcriptional regulator
C3766_17380	ENOG4105CAQ	asparagine synthetase
C3766_17405	ENOG4105DWK	Membrane
C3766_17410	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C3766_17420	ENOG4108NEV	two component transcriptional regulator, LytTR family
C3766_17430	ENOG4105D01	(LipO)protein
C3766_17435	ENOG4108UMI	ABC transporter, permease
C3766_17440	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C3766_17445	ENOG4105DKW	ABC transporter
C3766_17460	ENOG4105UQX	Mate efflux family protein
C3766_17465	ENOG4105X1N	Glycosyl transferase family 8
C3766_17470	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C3766_17475	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C3766_17495	ENOG4105C7K	acetolactate synthase
C3766_17500	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C3766_17505	ENOG4105BZ1	(ABC) transporter
C3766_17515	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
C3766_17520	ENOG4105EYF	MMPL domain protein
C3766_17535	ENOG4108TZY	GntR Family Transcriptional Regulator
C3766_17540	ENOG4107QRI	Phosphoketolase
C3766_17550	ENOG4105EAB	amino acid AbC transporter
C3766_17555	ENOG4105E5Q	amino acid AbC transporter
C3766_17560	ENOG4105CDA	abc transporter atp-binding protein
C3766_17585	ENOG4106M28	alanine racemase domain protein
C3766_17595	ENOG4105CDA	abc transporter atp-binding protein
C3766_17605	ENOG4105E5Q	amino acid AbC transporter
C3766_17615	ENOG4105DWT	malate dehydrogenase (quinone)
C3766_17620	ENOG4105CSH	Transporter
C3766_17660	ENOG4105C0H	protease
C3766_17665	ENOG4105Q2H	domain protein
C3766_17675	ENOG4105BZU	Histidine kinase
C3766_17680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C3766_17700	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C3766_17705	ENOG4105CDU	Replicative dna helicase
C3766_17710	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C3766_17715	ENOG4105BZR	domain protein
C3766_17725	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C3766_17730	ENOG4108UUM	single-stranded DNA-binding protein
C3766_17735	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C3766_17740	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C3766_17745	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C3766_17750	ENOG4108R6K	riboflavin synthase, subunit alpha
C3766_17755	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C3766_17760	ENOG4105C3G	gtp-binding protein
C3766_17765	ENOG4105VDK	protein, conserved in bacteria
C3766_17770	ENOG4105D8X	mechanosensitive ion channel
C3766_17775	ENOG4108ZDA	Sporulation protein YyaC
C3766_17785	ENOG4105FA0	parb-like partition protein
C3766_17790	ENOG4107QJE	Chromosome Partitioning Protein
C3766_17800	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
C3766_17805	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C3766_17810	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C3766_17815	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C3766_17825	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C3766_17830	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C3766_17835	ENOG4105VG0	50S ribosomal protein l34