locus-tag	class	description
AB434_0001	COG0183	Belongs to the thiolase family
AB434_0002	COG0183	Belongs to the thiolase family
AB434_0003	COG1024	Enoyl-CoA hydratase
AB434_0003	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_0005	COG1024	Enoyl-CoA hydratase
AB434_0005	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_0006	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_0006	COG1024	Enoyl-CoA hydratase
AB434_0008	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_0008	COG1024	Enoyl-CoA hydratase
AB434_0009	COG1024	Enoyl-CoA hydratase
AB434_0009	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_0012	COG5577	PFAM Coat F domain
AB434_0013	COG0772	Belongs to the SEDS family
AB434_0014	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB434_0017	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB434_0018	COG2202	Pas domain
AB434_0018	COG2199	diguanylate cyclase activity
AB434_0018	COG2200	EAL domain
AB434_0019	COG0753	catalase activity
AB434_0021	COG0671	phosphoesterase, PA-phosphatase related
AB434_0023	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AB434_0027	COG1595	DNA-templated transcription, initiation
AB434_0029	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AB434_0035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AB434_0037	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AB434_0038	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_0039	COG2211	Major facilitator Superfamily
AB434_0040	COG1904	glucuronate isomerase
AB434_0041	COG2721	sulfolactate sulfo-lyase activity
AB434_0042	COG0246	Mannitol dehydrogenase
AB434_0044	COG0800	Aldolase
AB434_0045	COG1414	Transcriptional regulator
AB434_0057	COG0557	exoribonuclease II activity
AB434_0058	COG1647	Serine aminopeptidase, S33
AB434_0060	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AB434_0062	COG0148	phosphopyruvate hydratase activity
AB434_0064	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AB434_0066	COG0126	phosphoglycerate kinase activity
AB434_0070	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AB434_0076	COG3383	formate dehydrogenase (NAD+) activity
AB434_0080	COG0840	transmembrane signaling receptor activity
AB434_0084	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB434_0087	COG4608	Belongs to the ABC transporter superfamily
AB434_0089	COG0791	NLP P60 protein
AB434_0090	COG4166	transmembrane transport
AB434_0091	COG0444	Belongs to the ABC transporter superfamily
AB434_0092	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB434_0093	COG0601	transmembrane transport
AB434_0094	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AB434_0096	COG0598	Magnesium transport protein CorA
AB434_0100	COG2719	SpoVR family
AB434_0101	COG3594	Acyltransferase
AB434_0107	COG1392	Phosphate transport regulator
AB434_0108	COG0306	phosphate transporter
AB434_0114	COG2766	serine protein kinase
AB434_0117	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AB434_0120	COG2095	MarC family integral membrane protein
AB434_0124	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AB434_0125	COG0596	Alpha beta hydrolase
AB434_0126	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB434_0127	COG0765	amino acid transport
AB434_0128	COG1126	abc transporter atp-binding protein
AB434_0129	COG2116	formate transmembrane transporter activity
AB434_0136	COG1882	Formate acetyltransferase
AB434_0137	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AB434_0138	COG0431	NADPH-dependent FMN reductase
AB434_0142	COG1131	(ABC) transporter
AB434_0150	COG0745	RESPONSE REGULATOR receiver
AB434_0151	COG3850	Histidine kinase
AB434_0151	COG5002	protein histidine kinase activity
AB434_0158	COG3104	oligopeptide transport
AB434_0159	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB434_0162	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB434_0171	COG2271	Major facilitator Superfamily
AB434_0173	COG0697	spore germination
AB434_0177	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB434_0179	COG2323	membrane
AB434_0183	COG3527	Alpha-acetolactate decarboxylase
AB434_0184	COG0028	Belongs to the TPP enzyme family
AB434_0185	COG0583	DNA-binding transcription factor activity
AB434_0187	COG0735	belongs to the Fur family
AB434_0191	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AB434_0192	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB434_0193	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB434_0194	COG1116	anion transmembrane transporter activity
AB434_0195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB434_0196	COG2814	Major facilitator Superfamily
AB434_0199	COG4129	membrane
AB434_0201	COG1737	Transcriptional regulator
AB434_0202	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_0202	COG1263	PTS System
AB434_0203	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AB434_0205	COG1132	(ABC) transporter
AB434_0206	COG3557	Belongs to the UPF0374 family
AB434_0209	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_0210	COG0583	DNA-binding transcription factor activity
AB434_0211	COG0069	glutamate synthase activity
AB434_0211	COG0067	glutamate synthase
AB434_0211	COG0070	glutamate synthase
AB434_0213	COG0493	'glutamate synthase
AB434_0219	COG1131	(ABC) transporter
AB434_0221	COG1988	membrane-bound metal-dependent
AB434_0222	COG1194	a g-specific adenine glycosylase
AB434_0224	COG3328	transposase activity
AB434_0230	COG0159	tryptophan synthase activity
AB434_0232	COG0133	tryptophan synthase activity
AB434_0233	COG0134	indole-3-glycerol-phosphate synthase activity
AB434_0235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AB434_0235	COG0512	Glutamine amidotransferase of anthranilate synthase
AB434_0238	COG0577	efflux transmembrane transporter activity
AB434_0239	COG1136	(ABC) transporter
AB434_0239	COG0577	efflux transmembrane transporter activity
AB434_0240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AB434_0242	COG1131	(ABC) transporter
AB434_0247	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB434_0251	COG1064	alcohol dehydrogenase
AB434_0257	COG2814	Major facilitator Superfamily
AB434_0258	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_0271	COG2197	response regulator
AB434_0272	COG4585	Histidine kinase
AB434_0276	COG1012	belongs to the aldehyde dehydrogenase family
AB434_0276	COG1012	belongs to the aldehyde dehydrogenase family
AB434_0279	COG0058	SHG alpha-glucan phosphorylase activity
AB434_0282	COG0840	transmembrane signaling receptor activity
AB434_0283	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB434_0284	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB434_0285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AB434_0288	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AB434_0289	COG0066	3-isopropylmalate dehydratase activity
AB434_0290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AB434_0292	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB434_0293	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AB434_0294	COG0440	acetolactate synthase activity
AB434_0295	COG0028	Belongs to the TPP enzyme family
AB434_0297	COG0129	dihydroxy-acid dehydratase activity
AB434_0299	COG1114	Component of the transport system for branched-chain amino acids
AB434_0300	COG1366	Belongs to the anti-sigma-factor antagonist family
AB434_0303	COG2124	cytochrome p450
AB434_0304	COG0670	Belongs to the BI1 family
AB434_0305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AB434_0306	COG2223	nitrite transmembrane transporter activity
AB434_0308	COG3279	Response regulator of the LytR AlgR family
AB434_0309	COG3275	phosphorelay sensor kinase activity
AB434_0310	COG0252	asparaginase activity
AB434_0312	COG2132	Multicopper oxidase
AB434_0314	COG1309	transcriptional regulator
AB434_0316	COG1511	domain protein
AB434_0326	COG0840	transmembrane signaling receptor activity
AB434_0326	COG5278	phosphoserine phosphatase activity
AB434_0327	COG3739	integral membrane protein
AB434_0328	COG3655	Transcriptional regulator
AB434_0331	COG1823	symporter activity
AB434_0332	COG2839	Protein conserved in bacteria
AB434_0336	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AB434_0337	COG0477	Major facilitator Superfamily
AB434_0340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AB434_0341	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AB434_0342	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AB434_0343	COG0840	transmembrane signaling receptor activity
AB434_0348	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB434_0349	COG1132	(ABC) transporter
AB434_0350	COG1846	Transcriptional regulator
AB434_0352	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AB434_0353	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AB434_0359	COG0387	Pfam Sodium calcium exchanger
AB434_0360	COG0477	Major facilitator Superfamily
AB434_0361	COG1295	ribonuclease BN
AB434_0362	COG4840	Belongs to the UPF0435 family
AB434_0363	COG0024	Methionine aminopeptidase
AB434_0364	COG0693	protein deglycase activity
AB434_0365	COG1360	Flagellar Motor Protein
AB434_0366	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AB434_0370	COG3189	MarR family transcriptional regulator
AB434_0373	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AB434_0374	COG1607	acyl-coa hydrolase
AB434_0376	COG1077	Cell shape determining protein MreB Mrl
AB434_0377	COG2268	Band 7 protein
AB434_0378	COG1585	Membrane protein implicated in regulation of membrane protease activity
AB434_0379	COG0626	cystathionine gamma-synthase activity
AB434_0380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AB434_0381	COG1854	S-ribosylhomocysteine lyase activity
AB434_0382	COG2226	methyltransferase
AB434_0383	COG0288	reversible hydration of carbon dioxide
AB434_0385	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB434_0386	COG2197	response regulator
AB434_0391	COG4086	secreted protein
AB434_0392	COG0737	Belongs to the 5'-nucleotidase family
AB434_0396	COG3620	sequence-specific DNA binding
AB434_0398	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AB434_0399	COG1518	maintenance of DNA repeat elements
AB434_0411	COG1304	FMN binding
AB434_0413	COG0166	Belongs to the GPI family
AB434_0415	COG0025	NhaP-type Na H and K H
AB434_0416	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB434_0416	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AB434_0416	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB434_0418	COG1349	DNA-binding transcription factor activity
AB434_0419	COG0371	Dehydrogenase
AB434_0422	COG0561	phosphatase activity
AB434_0426	COG2814	Major facilitator Superfamily
AB434_0427	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AB434_0431	COG2357	RelA SpoT domain protein
AB434_0433	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AB434_0436	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AB434_0437	COG1461	Dihydroxyacetone kinase
AB434_0438	COG2376	Dihydroxyacetone kinase
AB434_0442	COG0778	Nitroreductase
AB434_0443	COG1113	amino acid transport
AB434_0446	COG0730	response to heat
AB434_0448	COG2233	PERMEase
AB434_0452	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AB434_0457	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AB434_0458	COG1024	Enoyl-CoA hydratase
AB434_0459	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AB434_0460	COG0511	ligase activity, forming carbon-carbon bonds
AB434_0461	COG0439	Biotin carboxylase
AB434_0463	COG1960	acyl-CoA dehydrogenase activity
AB434_0464	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB434_0470	COG1349	DNA-binding transcription factor activity
AB434_0472	COG2376	Dihydroxyacetone kinase
AB434_0474	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AB434_0476	COG2271	Major facilitator Superfamily
AB434_0478	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_0480	COG0698	ribose 5-phosphate isomerase
AB434_0481	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AB434_0483	COG1494	fructose-1,6-bisphosphatase
AB434_0484	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB434_0486	COG3829	transcription factor binding
AB434_0490	COG0833	amino acid
AB434_0497	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AB434_0498	COG1140	nitrate reductase beta subunit
AB434_0500	COG2181	nitrate reductase activity
AB434_0501	COG2223	nitrite transmembrane transporter activity
AB434_0503	COG3588	fructose-bisphosphate aldolase
AB434_0506	COG4268	DNA restriction-modification system
AB434_0507	COG1401	restriction endodeoxyribonuclease activity
AB434_0508	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AB434_0523	COG0583	DNA-binding transcription factor activity
AB434_0524	COG0431	NADPH-dependent FMN reductase
AB434_0525	COG0454	-acetyltransferase
AB434_0526	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB434_0527	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB434_0528	COG0765	amino acid transport
AB434_0529	COG0765	amino acid transport
AB434_0530	COG1126	abc transporter atp-binding protein
AB434_0531	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB434_0532	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AB434_0533	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB434_0535	COG1280	lysine exporter protein (LysE YggA)
AB434_0537	COG0386	Belongs to the glutathione peroxidase family
AB434_0538	COG2190	(PTS) system
AB434_0541	COG1263	PTS System
AB434_0541	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_0542	COG0517	IMP dehydrogenase activity
AB434_0542	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AB434_0547	COG0281	malic enzyme
AB434_0549	COG3328	transposase activity
AB434_0551	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_0553	COG1301	dicarboxylic acid transport
AB434_0558	COG1328	CTP reductase activity
AB434_0561	COG1063	alcohol dehydrogenase
AB434_0563	COG3835	regulator
AB434_0564	COG1929	Belongs to the glycerate kinase type-1 family
AB434_0565	COG2610	gluconate transmembrane transporter activity
AB434_0566	COG1879	ABC-type sugar transport system periplasmic component
AB434_0567	COG1172	Belongs to the binding-protein-dependent transport system permease family
AB434_0568	COG1129	ABC transporter
AB434_0569	COG1869	D-ribose catabolic process
AB434_0570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB434_0571	COG1609	Transcriptional regulator
AB434_0580	COG4549	nuclear export factor GLE1
AB434_0581	COG2372	response to copper ion
AB434_0581	COG1276	copper resistance
AB434_0584	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AB434_0585	COG1609	Transcriptional regulator
AB434_0593	COG5002	protein histidine kinase activity
AB434_0594	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AB434_0596	COG1278	Cold shock
AB434_0601	COG0697	spore germination
AB434_0602	COG1472	Belongs to the glycosyl hydrolase 3 family
AB434_0605	COG3876	Protein conserved in bacteria
AB434_0608	COG1132	(ABC) transporter
AB434_0609	COG1132	(ABC) transporter
AB434_0613	COG0791	NLP P60 protein
AB434_0613	COG1388	LysM domain
AB434_0617	COG2272	Belongs to the type-B carboxylesterase lipase family
AB434_0618	COG0154	amidase activity
AB434_0619	COG2814	Major facilitator Superfamily
AB434_0620	COG1012	belongs to the aldehyde dehydrogenase family
AB434_0631	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AB434_0631	COG3153	acetyltransferase
AB434_0632	COG5583	Uncharacterized small protein (DUF2292)
AB434_0633	COG0431	NADPH-dependent FMN reductase
AB434_0634	COG1116	anion transmembrane transporter activity
AB434_0635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB434_0636	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB434_0637	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB434_0641	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AB434_0644	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AB434_0647	COG2390	Transcriptional regulator
AB434_0651	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AB434_0653	COG2252	PERMEase
AB434_0654	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AB434_0657	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AB434_0658	COG1984	allophanate hydrolase subunit 2
AB434_0659	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AB434_0661	COG2814	Major facilitator Superfamily
AB434_0662	COG1764	response to oxidative stress
AB434_0664	COG1126	abc transporter atp-binding protein
AB434_0665	COG0765	amino acid transport
AB434_0666	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB434_0669	COG0326	Molecular chaperone. Has ATPase activity
AB434_0686	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB434_0690	COG1064	alcohol dehydrogenase
AB434_0696	COG2814	Major facilitator Superfamily
AB434_0697	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_0706	COG3716	PTS system mannose fructose sorbose family IID component
AB434_0722	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB434_0724	COG1597	lipid kinase activity
AB434_0729	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AB434_0730	COG0154	amidase activity
AB434_0731	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AB434_0732	COG2224	Isocitrate lyase
AB434_0733	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AB434_0734	COG4851	CamS sex pheromone cAM373 precursor
AB434_0736	COG0210	DNA helicase
AB434_0737	COG0210	DNA helicase
AB434_0738	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AB434_0740	COG4496	protein, YerC YecD
AB434_0741	COG1470	cell adhesion involved in biofilm formation
AB434_0744	COG0151	Belongs to the GarS family
AB434_0745	COG0138	bifunctional purine biosynthesis protein purh
AB434_0746	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AB434_0747	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AB434_0748	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AB434_0749	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB434_0750	COG0047	phosphoribosylformylglycinamidine synthase activity
AB434_0751	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AB434_0753	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AB434_0754	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AB434_0755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AB434_0757	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AB434_0758	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AB434_0760	COG1263	PTS System
AB434_0760	COG2190	(PTS) system
AB434_0760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_0763	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_0763	COG1263	PTS System
AB434_0768	COG1301	dicarboxylic acid transport
AB434_0773	COG3711	transcriptional antiterminator
AB434_0774	COG2252	PERMEase
AB434_0777	COG1132	(ABC) transporter
AB434_0778	COG2814	Major facilitator Superfamily
AB434_0779	COG2197	response regulator
AB434_0780	COG3850	Histidine kinase
AB434_0781	COG1131	(ABC) transporter
AB434_0783	COG0842	Transport permease protein
AB434_0787	COG0179	Fumarylacetoacetate (FAA) hydrolase
AB434_0792	COG0824	Thioesterase
AB434_0793	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_0795	COG0183	Belongs to the thiolase family
AB434_0796	COG1024	Enoyl-CoA hydratase
AB434_0797	COG1024	Enoyl-CoA hydratase
AB434_0798	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_0799	COG2508	Transcriptional regulator
AB434_0800	COG2814	Major facilitator Superfamily
AB434_0802	COG0179	Fumarylacetoacetate (FAA) hydrolase
AB434_0805	COG0471	metal ion transport
AB434_0810	COG1131	(ABC) transporter
AB434_0811	COG1725	Transcriptional regulator
AB434_0813	COG1695	Transcriptional regulator
AB434_0814	COG3479	Phenolic acid decarboxylase
AB434_0816	COG2910	NAD(P)H-binding
AB434_0817	COG1959	2 iron, 2 sulfur cluster binding
AB434_0822	COG0425	Belongs to the sulfur carrier protein TusA family
AB434_0823	COG2391	methyltransferase activity
AB434_0826	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_0831	COG1120	ATPase activity
AB434_0832	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB434_0836	COG0519	Catalyzes the synthesis of GMP from XMP
AB434_0836	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AB434_0837	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AB434_0839	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AB434_0840	COG1335	isochorismatase
AB434_0841	COG4948	Mandelate Racemase Muconate Lactonizing
AB434_0843	COG0463	Glycosyl transferase, family 2
AB434_0844	COG2246	polysaccharide biosynthetic process
AB434_0845	COG0459	protein refolding
AB434_0846	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AB434_0848	COG1266	CAAX protease self-immunity
AB434_0850	COG0805	protein transport
AB434_0852	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AB434_0853	COG0488	(ABC) transporter
AB434_0856	COG0456	acetyltransferase
AB434_0857	COG1214	PFAM Peptidase M22, glycoprotease
AB434_0858	COG0802	atpase or kinase
AB434_0859	COG3091	SprT-like family
AB434_0861	COG2183	response to ionizing radiation
AB434_0862	COG2208	phosphoserine phosphatase activity
AB434_0863	COG1191	sigma factor activity
AB434_0864	COG2172	sigma factor antagonist activity
AB434_0865	COG1366	Belongs to the anti-sigma-factor antagonist family
AB434_0866	COG2208	phosphoserine phosphatase activity
AB434_0867	COG2172	sigma factor antagonist activity
AB434_0868	COG1366	Belongs to the anti-sigma-factor antagonist family
AB434_0869	COG1366	Belongs to the anti-sigma-factor antagonist family
AB434_0873	COG2337	Toxic component of a toxin-antitoxin (TA) module
AB434_0874	COG0864	Transcriptional regulator
AB434_0876	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AB434_0877	COG0736	holo-[acyl-carrier-protein] synthase activity
AB434_0878	COG0705	Rhomboid family
AB434_0880	COG0513	Belongs to the DEAD box helicase family
AB434_0883	COG1280	lysine exporter protein (LysE YggA)
AB434_0886	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB434_0887	COG1609	Transcriptional regulator
AB434_0890	COG2182	Extracellular solute-binding protein
AB434_0892	COG1175	transmembrane transport
AB434_0893	COG3833	ABC-type maltose transport systems, permease component
AB434_0895	COG1554	hydrolase, family 65, central catalytic
AB434_0898	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AB434_0899	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB434_0903	COG1253	flavin adenine dinucleotide binding
AB434_0904	COG0789	Transcriptional regulator
AB434_0905	COG1253	flavin adenine dinucleotide binding
AB434_0909	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AB434_0913	COG0629	single-stranded DNA binding
AB434_0916	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AB434_0918	COG4786	Flagellar basal body rod
AB434_0919	COG4786	Flagellar basal body rod
AB434_0920	COG1077	Cell shape determining protein MreB Mrl
AB434_0921	COG1609	Transcriptional regulator
AB434_0923	COG0739	heme binding
AB434_0924	COG2385	sporulation resulting in formation of a cellular spore
AB434_0926	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB434_0929	COG4836	Membrane
AB434_0930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AB434_0931	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AB434_0932	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AB434_0933	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AB434_0934	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB434_0936	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AB434_0937	COG0356	it plays a direct role in the translocation of protons across the membrane
AB434_0939	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AB434_0941	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AB434_0943	COG0698	ribose 5-phosphate isomerase
AB434_0947	COG1971	Probably functions as a manganese efflux pump
AB434_0948	COG0009	L-threonylcarbamoyladenylate synthase
AB434_0951	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AB434_0953	COG1435	thymidine kinase activity
AB434_0955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AB434_0957	COG1494	fructose-1,6-bisphosphatase
AB434_0958	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AB434_0960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AB434_0961	COG0191	fructose-bisphosphate aldolase activity
AB434_0962	COG2204	response regulator
AB434_0965	COG1131	(ABC) transporter
AB434_0966	COG1725	Transcriptional regulator
AB434_0967	COG0504	CTP synthase activity
AB434_0973	COG1136	(ABC) transporter
AB434_0975	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AB434_0975	COG1703	isobutyryl-CoA mutase activity
AB434_0975	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AB434_0976	COG1309	transcriptional regulator
AB434_0977	COG1960	acyl-CoA dehydrogenase activity
AB434_0978	COG1960	acyl-CoA dehydrogenase activity
AB434_0979	COG0183	Belongs to the thiolase family
AB434_0980	COG2181	nitrate reductase activity
AB434_0980	COG0247	lactate metabolic process
AB434_0982	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AB434_0983	COG0018	arginyl-trna synthetase
AB434_0985	COG0010	Belongs to the arginase family
AB434_0986	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB434_0988	COG1994	Peptidase M50
AB434_0990	COG3465	dGTPase activity
AB434_0991	COG1078	dGTPase activity
AB434_0995	COG0095	Lipoate-protein ligase
AB434_0997	COG0280	phosphate acetyltransferase
AB434_1000	COG2363	Small membrane protein
AB434_1003	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AB434_1006	COG4555	ABC transporter
AB434_1011	COG0351	phosphomethylpyrimidine kinase
AB434_1014	COG0561	phosphatase activity
AB434_1015	COG0514	ATP-dependent DNA helicase (RecQ)
AB434_1016	COG1785	Belongs to the alkaline phosphatase family
AB434_1017	COG1737	Transcriptional regulator
AB434_1020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB434_1022	COG1346	cytolysis
AB434_1023	COG1380	Effector of murein hydrolase LrgA
AB434_1024	COG0583	DNA-binding transcription factor activity
AB434_1025	COG0367	asparagine synthase
AB434_1030	COG2966	Psort location CytoplasmicMembrane, score
AB434_1031	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AB434_1032	COG1966	Carbon starvation protein
AB434_1034	COG3275	phosphorelay sensor kinase activity
AB434_1035	COG1464	Belongs to the NlpA lipoprotein family
AB434_1036	COG2011	ABC-type metal ion transport system permease component
AB434_1037	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AB434_1038	COG1119	ATPase activity
AB434_1042	COG0534	Mate efflux family protein
AB434_1044	COG1442	glycosyl transferase family 8
AB434_1045	COG2195	Cleaves the N-terminal amino acid of tripeptides
AB434_1046	COG2814	Major facilitator Superfamily
AB434_1048	COG0028	Belongs to the TPP enzyme family
AB434_1050	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AB434_1052	COG1132	(ABC) transporter
AB434_1054	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AB434_1059	COG2188	Transcriptional regulator
AB434_1060	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AB434_1061	COG1366	Belongs to the anti-sigma-factor antagonist family
AB434_1062	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB434_1064	COG1126	abc transporter atp-binding protein
AB434_1070	COG3457	Alanine racemase
AB434_1072	COG1126	abc transporter atp-binding protein
AB434_1074	COG0765	amino acid transport
AB434_1076	COG0579	oxidoreductase
AB434_1077	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AB434_1078	COG0732	type I restriction modification DNA specificity domain
AB434_1079	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AB434_1085	COG3328	transposase activity
AB434_1096	COG1280	lysine exporter protein (LysE YggA)
AB434_1098	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AB434_1104	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AB434_1105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB434_1106	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AB434_1107	COG4853	Protein conserved in bacteria
AB434_1108	COG4863	YycH protein
AB434_1109	COG5002	protein histidine kinase activity
AB434_1110	COG0745	RESPONSE REGULATOR receiver
AB434_1112	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AB434_1114	COG0305	Participates in initiation and elongation during chromosome replication
AB434_1116	COG0359	binds to the 23S rRNA
AB434_1117	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AB434_1119	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AB434_1121	COG0360	Binds together with S18 to 16S ribosomal RNA
AB434_1122	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AB434_1124	COG0307	riboflavin synthase, alpha
AB434_1125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB434_1125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AB434_1126	COG0012	GTP binding
AB434_1127	COG4481	Protein conserved in bacteria
AB434_1128	COG0668	transmembrane transport
AB434_1133	COG1475	DNA binding
AB434_1134	COG1192	Involved in chromosome partitioning
AB434_1136	COG1475	DNA binding
AB434_1137	COG0357	Ribosomal RNA small subunit methyltransferase G
AB434_1138	COG0445	tRNA wobble uridine modification
AB434_1139	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AB434_1140	COG1847	R3H domain protein
AB434_1141	COG0706	membrane insertase activity
AB434_1142	COG0594	ribonuclease P activity
AB434_1143	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AB434_1145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AB434_1146	COG0592	DNA-directed DNA polymerase activity
AB434_1147	COG2501	S4 domain
AB434_1148	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AB434_1150	COG0187	DNA topoisomerase II activity
AB434_1151	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AB434_1152	COG3437	response regulator, receiver
AB434_1154	COG3328	transposase activity
AB434_1156	COG1982	Orn Lys Arg decarboxylase major
AB434_1158	COG3870	Protein conserved in bacteria
AB434_1159	COG1728	Protein conserved in bacteria
AB434_1160	COG0470	DNA polymerase III
AB434_1161	COG1774	PSP1 C-terminal conserved region
AB434_1162	COG4467	Involved in initiation control of chromosome replication
AB434_1163	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AB434_1164	COG2827	Endonuclease containing a URI domain
AB434_1165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AB434_1166	COG2002	toxin-antitoxin pair type II binding
AB434_1168	COG0084	hydrolase, TatD family'
AB434_1170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AB434_1173	COG4466	Protein conserved in bacteria
AB434_1175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AB434_1177	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AB434_1178	COG0251	oxidation-reduction process
AB434_1182	COG1136	(ABC) transporter
AB434_1182	COG0577	efflux transmembrane transporter activity
AB434_1184	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AB434_1185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AB434_1186	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AB434_1188	COG0193	aminoacyl-tRNA hydrolase activity
AB434_1190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AB434_1192	COG2002	toxin-antitoxin pair type II binding
AB434_1193	COG2244	polysaccharide biosynthetic process
AB434_1194	COG3956	TIGRFAM MazG family protein
AB434_1195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AB434_1199	COG1098	S1 RNA binding domain
AB434_1202	COG2208	phosphoserine phosphatase activity
AB434_1203	COG2304	oxidoreductase activity
AB434_1204	COG0515	serine threonine protein kinase
AB434_1206	COG0037	tRNA processing
AB434_1208	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AB434_1209	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AB434_1210	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AB434_1212	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AB434_1213	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AB434_1214	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AB434_1215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AB434_1218	COG0517	IMP dehydrogenase activity
AB434_1218	COG0516	GMP reductase activity
AB434_1222	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AB434_1223	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AB434_1224	COG1428	Deoxynucleoside kinase
AB434_1225	COG1428	Deoxynucleoside kinase
AB434_1226	COG3858	chitin binding
AB434_1226	COG1388	LysM domain
AB434_1228	COG3328	transposase activity
AB434_1232	COG0590	tRNA wobble adenosine to inosine editing
AB434_1233	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AB434_1235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AB434_1240	COG3880	PFAM UvrB UvrC protein
AB434_1241	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AB434_1242	COG0542	response to heat
AB434_1243	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AB434_1244	COG4956	integral membrane protein (PIN domain superfamily)
AB434_1246	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AB434_1248	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AB434_1250	COG1045	serine acetyltransferase
AB434_1251	COG0215	cysteine-tRNA ligase activity
AB434_1253	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB434_1254	COG3688	RNA-binding protein containing a PIN domain
AB434_1256	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AB434_1257	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AB434_1258	COG0250	Participates in transcription elongation, termination and antitermination
AB434_1259	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AB434_1260	COG0081	regulation of translation
AB434_1262	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AB434_1264	COG2813	Specifically methylates the guanine in position
AB434_1267	COG1358	cellular component organization or biogenesis
AB434_1268	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AB434_1269	COG0049	tRNA binding
AB434_1270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AB434_1272	COG0051	transcription antitermination factor activity, RNA binding
AB434_1274	COG0088	Forms part of the polypeptide exit tunnel
AB434_1275	COG0089	rRNA binding
AB434_1276	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AB434_1277	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AB434_1278	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AB434_1279	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AB434_1280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AB434_1281	COG0255	Belongs to the universal ribosomal protein uL29 family
AB434_1282	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AB434_1283	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AB434_1284	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AB434_1286	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AB434_1287	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AB434_1288	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AB434_1289	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AB434_1290	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AB434_1291	COG1841	ribosomal large subunit assembly
AB434_1292	COG0200	Binds to the 23S rRNA
AB434_1293	COG0201	protein transport
AB434_1294	COG0563	adenylate kinase activity
AB434_1296	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AB434_1297	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AB434_1298	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AB434_1299	COG0202	RNA polymerase activity
AB434_1300	COG0203	ribosomal protein L17
AB434_1302	COG1122	ATPase activity
AB434_1303	COG1122	ATPase activity
AB434_1304	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AB434_1308	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AB434_1309	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AB434_1314	COG2046	Belongs to the sulfate adenylyltransferase family
AB434_1315	COG0529	Catalyzes the synthesis of activated sulfate
AB434_1316	COG0833	amino acid
AB434_1318	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB434_1319	COG0489	protein tyrosine kinase activity
AB434_1321	COG2194	sulfuric ester hydrolase activity
AB434_1324	COG0726	polysaccharide deacetylase
AB434_1326	COG1271	oxidase subunit
AB434_1327	COG1294	oxidase, subunit
AB434_1329	COG4988	ABC transporter
AB434_1330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AB434_1332	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_1336	COG1525	nuclease
AB434_1344	COG5377	YqaJ viral recombinase family
AB434_1345	COG3723	Recombinational DNA repair protein, rece pathway
AB434_1346	COG3935	DnaD domain protein
AB434_1347	COG0305	Participates in initiation and elongation during chromosome replication
AB434_1378	COG1388	LysM domain
AB434_1378	COG3942	CHAP domain
AB434_1382	COG1595	DNA-templated transcription, initiation
AB434_1383	COG5662	AntiSigma factor
AB434_1384	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AB434_1385	COG4856	YbbR-like protein
AB434_1386	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB434_1388	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AB434_1403	COG2814	Major facilitator Superfamily
AB434_1404	COG0583	DNA-binding transcription factor activity
AB434_1405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AB434_1406	COG0840	transmembrane signaling receptor activity
AB434_1410	COG0840	transmembrane signaling receptor activity
AB434_1420	COG1181	Belongs to the D-alanine--D-alanine ligase family
AB434_1425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AB434_1426	COG2814	Major facilitator Superfamily
AB434_1430	COG0519	Catalyzes the synthesis of GMP from XMP
AB434_1435	COG0477	Major facilitator Superfamily
AB434_1435	COG2814	Major facilitator Superfamily
AB434_1444	COG3425	synthase
AB434_1446	COG0183	Belongs to the thiolase family
AB434_1453	COG1125	glycine betaine transport
AB434_1453	COG0517	IMP dehydrogenase activity
AB434_1454	COG1174	glycine betaine transport
AB434_1456	COG2190	(PTS) system
AB434_1457	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_1457	COG1263	PTS System
AB434_1458	COG0366	Alpha amylase catalytic
AB434_1459	COG2188	Transcriptional regulator
AB434_1462	COG1070	Carbohydrate kinase
AB434_1464	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AB434_1466	COG0716	FMN binding
AB434_1468	COG5002	protein histidine kinase activity
AB434_1470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB434_1473	COG2217	Heavy metal translocating P-type atpase
AB434_1475	COG3328	transposase activity
AB434_1478	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB434_1480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB434_1481	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AB434_1482	COG0463	Glycosyl transferase, family 2
AB434_1489	COG2076	Multidrug Resistance protein
AB434_1490	COG2076	Multidrug Resistance protein
AB434_1492	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB434_1493	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB434_1494	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AB434_1495	COG1120	ATPase activity
AB434_1503	COG0217	transcriptional regulatory protein
AB434_1504	COG1366	Belongs to the anti-sigma-factor antagonist family
AB434_1507	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_1508	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_1509	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_1510	COG1309	transcriptional regulator
AB434_1515	COG1012	belongs to the aldehyde dehydrogenase family
AB434_1518	COG5434	Belongs to the glycosyl hydrolase 28 family
AB434_1520	COG0175	sulfate reduction
AB434_1527	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AB434_1529	COG3328	transposase activity
AB434_1530	COG0371	Dehydrogenase
AB434_1531	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_1533	COG0745	RESPONSE REGULATOR receiver
AB434_1533	COG3706	GGDEF domain
AB434_1536	COG0697	spore germination
AB434_1541	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AB434_1545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AB434_1550	COG0702	epimerase
AB434_1553	COG2213	PTS system mannitol-specific
AB434_1553	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB434_1554	COG3711	transcriptional antiterminator
AB434_1555	COG0246	Mannitol dehydrogenase
AB434_1557	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AB434_1560	COG3830	Belongs to the UPF0237 family
AB434_1561	COG2848	UPF0210 protein
AB434_1562	COG1609	Transcriptional regulator
AB434_1564	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AB434_1567	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AB434_1573	COG5577	PFAM Coat F domain
AB434_1574	COG0667	Aldo Keto reductase
AB434_1577	COG1113	amino acid transport
AB434_1579	COG3104	oligopeptide transport
AB434_1580	COG0833	amino acid
AB434_1583	COG3842	ATPase activity
AB434_1584	COG1176	ABC-type spermidine putrescine transport system, permease component I
AB434_1586	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AB434_1590	COG3328	transposase activity
AB434_1596	COG3328	transposase activity
AB434_1598	COG0531	amino acid
AB434_1599	COG1556	Lactate utilization protein
AB434_1600	COG1139	Iron-sulfur cluster binding protein
AB434_1601	COG0247	lactate metabolic process
AB434_1603	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AB434_1604	COG1454	alcohol dehydrogenase
AB434_1606	COG1953	Uracil, thiamine, allantoin
AB434_1611	COG0531	amino acid
AB434_1612	COG1979	alcohol dehydrogenase
AB434_1614	COG0004	ammonium transporteR
AB434_1615	COG3290	protein histidine kinase activity
AB434_1616	COG4565	transcriptional regulatory protein
AB434_1617	COG2851	Citrate transporter
AB434_1619	COG0463	Glycosyl transferase, family 2
AB434_1620	COG3973	AAA domain
AB434_1623	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AB434_1624	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AB434_1625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AB434_1626	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AB434_1627	COG1301	dicarboxylic acid transport
AB434_1628	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AB434_1633	COG1902	pentaerythritol trinitrate reductase activity
AB434_1638	COG0423	glycine-tRNA ligase activity
AB434_1639	COG0531	amino acid
AB434_1642	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AB434_1644	COG0628	permease
AB434_1648	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB434_1649	COG0765	amino acid transport
AB434_1650	COG0765	amino acid transport
AB434_1653	COG1733	regulation of RNA biosynthetic process
AB434_1656	COG0586	Pfam SNARE associated Golgi protein
AB434_1657	COG0586	Pfam SNARE associated Golgi protein
AB434_1662	COG1316	TRANSCRIPTIONal
AB434_1664	COG0646	methionine synthase
AB434_1664	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AB434_1665	COG0646	methionine synthase
AB434_1665	COG1410	methionine synthase
AB434_1673	COG3944	biosynthesis protein
AB434_1674	COG0489	protein tyrosine kinase activity
AB434_1675	COG4464	protein tyrosine phosphatase activity
AB434_1676	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AB434_1677	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AB434_1682	COG0662	Cupin 2, conserved barrel domain protein
AB434_1682	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AB434_1683	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AB434_1688	COG1501	Belongs to the glycosyl hydrolase 31 family
AB434_1690	COG2115	Belongs to the xylose isomerase family
AB434_1691	COG1070	Carbohydrate kinase
AB434_1697	COG1070	Carbohydrate kinase
AB434_1699	COG1940	carbohydrate kinase activity
AB434_1701	COG1063	alcohol dehydrogenase
AB434_1702	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AB434_1703	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AB434_1710	COG4193	domain, Protein
AB434_1719	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AB434_1723	COG5504	Zn-dependent protease
AB434_1724	COG2226	methyltransferase
AB434_1733	COG3716	PTS system mannose fructose sorbose family IID component
AB434_1734	COG3715	PTS system
AB434_1735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_1737	COG0363	glucosamine-6-phosphate deaminase activity
AB434_1738	COG2188	Transcriptional regulator
AB434_1739	COG1396	sequence-specific DNA binding
AB434_1741	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AB434_1742	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AB434_1744	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AB434_1744	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AB434_1746	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB434_1746	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_1747	COG3715	PTS system
AB434_1748	COG3716	PTS system mannose fructose sorbose family IID component
AB434_1752	COG3414	Phosphotransferase system galactitol-specific IIB component
AB434_1753	COG3775	system Galactitol-specific IIC component
AB434_1755	COG1105	Belongs to the carbohydrate kinase PfkB family
AB434_1756	COG0235	Class ii aldolase
AB434_1760	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AB434_1762	COG0145	ligase activity
AB434_1764	COG2315	Protein conserved in bacteria
AB434_1767	COG2333	competence protein COMEC
AB434_1767	COG0658	competence protein
AB434_1769	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AB434_1773	COG0531	amino acid
AB434_1774	COG1316	TRANSCRIPTIONal
AB434_1776	COG4989	oxidoreductase activity
AB434_1782	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AB434_1784	COG2130	NADP-dependent
AB434_1786	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB434_1786	COG3711	transcriptional antiterminator
AB434_1787	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB434_1788	COG1447	Phosphotransferase system cellobiose-specific component IIA
AB434_1790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB434_1791	COG2211	Major facilitator Superfamily
AB434_1791	COG2190	(PTS) system
AB434_1794	COG1113	amino acid transport
AB434_1798	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AB434_1800	COG2814	Major facilitator Superfamily
AB434_1801	COG1609	Transcriptional regulator
AB434_1804	COG1174	glycine betaine transport
AB434_1805	COG1732	Glycine betaine
AB434_1806	COG1174	glycine betaine transport
AB434_1807	COG1125	glycine betaine transport
AB434_1807	COG0517	IMP dehydrogenase activity
AB434_1808	COG1510	regulation of RNA biosynthetic process
AB434_1809	COG0110	maltose O-acetyltransferase activity
AB434_1810	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_1813	COG4297	protein containing double-stranded beta helix domain
AB434_1816	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB434_1820	COG2272	Belongs to the type-B carboxylesterase lipase family
AB434_1821	COG0606	chelatase, subunit chli
AB434_1825	COG0371	Dehydrogenase
AB434_1826	COG2814	Major facilitator Superfamily
AB434_1827	COG1070	Carbohydrate kinase
AB434_1828	COG2115	Belongs to the xylose isomerase family
AB434_1831	COG0157	Belongs to the NadC ModD family
AB434_1832	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AB434_1833	COG1104	cysteine desulfurase activity
AB434_1837	COG2116	formate transmembrane transporter activity
AB434_1842	COG4720	Psort location CytoplasmicMembrane, score
AB434_1846	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_1847	COG2610	gluconate transmembrane transporter activity
AB434_1849	COG1012	belongs to the aldehyde dehydrogenase family
AB434_1851	COG3829	transcription factor binding
AB434_1851	COG3290	protein histidine kinase activity
AB434_1853	COG1501	Belongs to the glycosyl hydrolase 31 family
AB434_1858	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_1860	COG1309	transcriptional regulator
AB434_1863	COG1363	Peptidase, m42
AB434_1871	COG2972	Histidine kinase
AB434_1875	COG0531	amino acid
AB434_1877	COG1620	l-lactate permease
AB434_1878	COG2186	Transcriptional regulator
AB434_1887	COG0473	3-isopropylmalate dehydrogenase activity
AB434_1888	COG0473	3-isopropylmalate dehydrogenase activity
AB434_1896	COG1447	Phosphotransferase system cellobiose-specific component IIA
AB434_1900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB434_1900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AB434_1901	COG2723	6-phospho-beta-galactosidase activity
AB434_1902	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB434_1902	COG3711	transcriptional antiterminator
AB434_1903	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AB434_1906	COG1131	(ABC) transporter
AB434_1908	COG0626	cystathionine gamma-synthase activity
AB434_1909	COG0626	cystathionine gamma-synthase activity
AB434_1914	COG1653	transport
AB434_1915	COG2207	Transcriptional regulator
AB434_1919	COG0604	alcohol dehydrogenase
AB434_1920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AB434_1921	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AB434_1928	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_1930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AB434_1932	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AB434_1934	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB434_1935	COG1316	TRANSCRIPTIONal
AB434_1936	COG1136	(ABC) transporter
AB434_1936	COG0577	efflux transmembrane transporter activity
AB434_1938	COG3328	transposase activity
AB434_1940	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AB434_1943	COG0039	L-malate dehydrogenase activity
AB434_1945	COG1388	LysM domain
AB434_1945	COG3584	3D domain protein
AB434_1947	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB434_1950	COG0011	TIGRFAM Protein of
AB434_1951	COG2706	6-phosphogluconolactonase activity
AB434_1954	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AB434_1954	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AB434_1955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_1955	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB434_1957	COG3715	PTS system
AB434_1958	COG3716	PTS system mannose fructose sorbose family IID component
AB434_1961	COG2079	MmgE PrpD family protein
AB434_1962	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AB434_1964	COG0154	amidase activity
AB434_1966	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB434_1967	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB434_1968	COG1116	anion transmembrane transporter activity
AB434_1969	COG0083	homoserine kinase activity
AB434_1970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AB434_1971	COG0460	homoserine dehydrogenase
AB434_1972	COG0010	Belongs to the arginase family
AB434_1975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AB434_1976	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AB434_1979	COG4145	pantothenate transmembrane transporter activity
AB434_1983	COG1012	belongs to the aldehyde dehydrogenase family
AB434_1983	COG1454	alcohol dehydrogenase
AB434_1986	COG1388	LysM domain
AB434_1986	COG0791	NLP P60 protein
AB434_1987	COG0024	Methionine aminopeptidase
AB434_1990	COG1268	BioY protein
AB434_1992	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_1993	COG1960	acyl-CoA dehydrogenase activity
AB434_1994	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_1995	COG2746	aminoglycoside 3-N-acetyltransferase activity
AB434_1996	COG2244	polysaccharide biosynthetic process
AB434_1997	COG0589	response to stress
AB434_2000	COG0535	radical SAM domain protein
AB434_2002	COG0457	Tetratricopeptide repeat
AB434_2004	COG1063	alcohol dehydrogenase
AB434_2006	COG2211	Major facilitator Superfamily
AB434_2007	COG2211	Major facilitator Superfamily
AB434_2009	COG1609	Transcriptional regulator
AB434_2011	COG0561	phosphatase activity
AB434_2016	COG0656	L-ascorbic acid biosynthetic process
AB434_2021	COG0656	L-ascorbic acid biosynthetic process
AB434_2023	COG0431	NADPH-dependent FMN reductase
AB434_2024	COG0420	3'-5' exonuclease activity
AB434_2025	COG4717	serine-type aminopeptidase activity
AB434_2026	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_2027	COG0534	Mate efflux family protein
AB434_2031	COG1664	Polymer-forming cytoskeletal
AB434_2034	COG0789	Transcriptional regulator
AB434_2035	COG0436	Aminotransferase
AB434_2037	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AB434_2039	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB434_2042	COG2226	methyltransferase
AB434_2045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AB434_2061	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AB434_2062	COG1113	amino acid transport
AB434_2063	COG2814	Major facilitator Superfamily
AB434_2066	COG2409	Drug exporters of the RND superfamily
AB434_2066	COG1033	growth of symbiont in host cell
AB434_2067	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AB434_2069	COG1960	acyl-CoA dehydrogenase activity
AB434_2070	COG1960	acyl-CoA dehydrogenase activity
AB434_2075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AB434_2076	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AB434_2079	COG1609	Transcriptional regulator
AB434_2084	COG2996	Protein conserved in bacteria
AB434_2085	COG0346	lactoylglutathione lyase activity
AB434_2089	COG1482	cell wall glycoprotein biosynthetic process
AB434_2091	COG0477	Major facilitator Superfamily
AB434_2092	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AB434_2095	COG0791	NLP P60 protein
AB434_2095	COG1388	LysM domain
AB434_2097	COG0768	penicillin binding
AB434_2099	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB434_2102	COG1739	Uncharacterized protein family UPF0029
AB434_2104	COG2197	response regulator
AB434_2106	COG0531	amino acid
AB434_2108	COG1307	EDD domain protein, DegV family
AB434_2109	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AB434_2110	COG1040	competence protein
AB434_2112	COG2747	anti-sigma28 factor FlgM
AB434_2114	COG4786	Flagellar basal body rod
AB434_2114	COG1256	bacterial-type flagellum assembly
AB434_2115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AB434_2117	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AB434_2121	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AB434_2122	COG1285	pathogenesis
AB434_2123	COG0647	UMP catabolic process
AB434_2125	COG2271	Major facilitator Superfamily
AB434_2127	COG1113	amino acid transport
AB434_2129	COG1113	amino acid transport
AB434_2132	COG1067	ATP-dependent peptidase activity
AB434_2137	COG2094	Belongs to the DNA glycosylase MPG family
AB434_2141	COG1334	flagellar protein FlaG
AB434_2142	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AB434_2143	COG1516	flagellar protein fliS
AB434_2151	COG0653	protein targeting
AB434_2152	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AB434_2153	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB434_2156	COG2884	Cell division ATP-binding protein ftsE
AB434_2157	COG2177	Part of the ABC transporter FtsEX involved in
AB434_2158	COG0739	heme binding
AB434_2162	COG0460	homoserine dehydrogenase
AB434_2163	COG0793	Belongs to the peptidase S41A family
AB434_2163	COG3409	Peptidoglycan-binding domain 1 protein
AB434_2165	COG3328	transposase activity
AB434_2166	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AB434_2167	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AB434_2168	COG4605	iron ion homeostasis
AB434_2169	COG4604	ABC transporter, ATP-binding protein
AB434_2170	COG4607	ABC-type enterochelin transport system periplasmic component
AB434_2174	COG0745	RESPONSE REGULATOR receiver
AB434_2175	COG5002	protein histidine kinase activity
AB434_2177	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AB434_2180	COG0573	inorganic phosphate transmembrane transporter activity
AB434_2181	COG0581	inorganic phosphate transmembrane transporter activity
AB434_2182	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AB434_2183	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AB434_2194	COG0556	nucleotide-excision repair
AB434_2195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AB434_2197	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AB434_2199	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AB434_2200	COG1682	transport, permease protein
AB434_2201	COG0463	Glycosyl transferase, family 2
AB434_2201	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AB434_2204	COG3595	metallopeptidase activity
AB434_2206	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AB434_2207	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AB434_2210	COG0546	phosphoglycolate phosphatase activity
AB434_2211	COG0110	maltose O-acetyltransferase activity
AB434_2212	COG0457	Tetratricopeptide repeat
AB434_2214	COG0492	ferredoxin-NADP+ reductase activity
AB434_2217	COG1051	belongs to the nudix hydrolase family
AB434_2218	COG1660	Displays ATPase and GTPase activities
AB434_2219	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AB434_2221	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB434_2229	COG3842	ATPase activity
AB434_2230	COG2508	Transcriptional regulator
AB434_2232	COG0189	ligase activity
AB434_2233	COG0189	ligase activity
AB434_2236	COG4399	Belongs to the UPF0754 family
AB434_2238	COG0561	phosphatase activity
AB434_2239	COG1024	Enoyl-CoA hydratase
AB434_2241	COG0861	Integral membrane protein TerC family
AB434_2244	COG0701	Predicted permease
AB434_2245	COG3689	TIGRFAM TIGR03943 family protein
AB434_2246	COG0420	3'-5' exonuclease activity
AB434_2247	COG4717	serine-type aminopeptidase activity
AB434_2248	COG3481	metal-dependent phosphohydrolase, HD sub domain
AB434_2250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AB434_2255	COG1846	Transcriptional regulator
AB434_2261	COG0537	adenosine 5'-monophosphoramidase activity
AB434_2263	COG1131	(ABC) transporter
AB434_2264	COG4473	ABC transporter
AB434_2266	COG1473	amidohydrolase
AB434_2267	COG3069	C4-dicarboxylate transmembrane transporter activity
AB434_2268	COG2329	Antibiotic biosynthesis monooxygenase
AB434_2270	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AB434_2273	COG1309	transcriptional regulator
AB434_2274	COG1511	domain protein
AB434_2275	COG1263	PTS System
AB434_2275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_2275	COG1263	PTS System
AB434_2275	COG2190	(PTS) system
AB434_2275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AB434_2275	COG2190	(PTS) system
AB434_2276	COG1349	DNA-binding transcription factor activity
AB434_2278	COG3254	rhamnose metabolic process
AB434_2279	COG2814	Major facilitator Superfamily
AB434_2280	COG0697	spore germination
AB434_2282	COG1012	belongs to the aldehyde dehydrogenase family
AB434_2283	COG1999	signal sequence binding
AB434_2286	COG0095	Lipoate-protein ligase
AB434_2287	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_2288	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AB434_2290	COG0501	Belongs to the peptidase M48B family
AB434_2295	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AB434_2296	COG1074	ATP-dependent DNA helicase activity
AB434_2304	COG2311	Membrane
AB434_2305	COG0179	Fumarylacetoacetate (FAA) hydrolase
AB434_2308	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_2309	COG1307	EDD domain protein, DegV family
AB434_2313	COG0561	phosphatase activity
AB434_2314	COG2151	metal-sulfur cluster biosynthetic enzyme
AB434_2322	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB434_2323	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AB434_2327	COG4608	Belongs to the ABC transporter superfamily
AB434_2328	COG0601	transmembrane transport
AB434_2330	COG0747	negative chemotaxis
AB434_2332	COG0180	Tryptophanyl-tRNA synthetase
AB434_2334	COG4166	transmembrane transport
AB434_2335	COG0601	transmembrane transport
AB434_2336	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AB434_2337	COG0444	Belongs to the ABC transporter superfamily
AB434_2338	COG4608	Belongs to the ABC transporter superfamily
AB434_2340	COG1393	Belongs to the ArsC family
AB434_2342	COG4862	establishment of competence for transformation
AB434_2344	COG4469	Competence protein
AB434_2345	COG1164	Oligoendopeptidase f
AB434_2350	COG2346	COG2346, Truncated hemoglobins
AB434_2355	COG3328	transposase activity
AB434_2358	COG0741	lytic transglycosylase activity
AB434_2361	COG2357	RelA SpoT domain protein
AB434_2362	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AB434_2363	COG0564	pseudouridine synthase activity
AB434_2366	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AB434_2367	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AB434_2378	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AB434_2381	COG3328	transposase activity
AB434_2388	COG2153	protein acetylation
AB434_2390	COG2382	esterase
AB434_2403	COG1940	carbohydrate kinase activity
AB434_2406	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_2409	COG4152	abc transporter atp-binding protein
AB434_2410	COG1668	transmembrane transport
AB434_2414	COG3579	cysteine-type endopeptidase activity
AB434_2425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB434_2426	COG3344	reverse transcriptase
AB434_2427	COG2059	Chromate
AB434_2428	COG2059	Chromate
AB434_2429	COG1522	sequence-specific DNA binding
AB434_2435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AB434_2436	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AB434_2439	COG0842	Transport permease protein
AB434_2439	COG1511	domain protein
AB434_2442	COG1609	Transcriptional regulator
AB434_2444	COG1554	hydrolase, family 65, central catalytic
AB434_2445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AB434_2460	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_2466	COG1959	2 iron, 2 sulfur cluster binding
AB434_2470	COG0730	response to heat
AB434_2472	COG0783	Belongs to the Dps family
AB434_2474	COG0673	inositol 2-dehydrogenase activity
AB434_2475	COG3852	Histidine kinase
AB434_2476	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AB434_2479	COG0861	Integral membrane protein TerC family
AB434_2486	COG5002	protein histidine kinase activity
AB434_2490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AB434_2496	COG0542	response to heat
AB434_2497	COG3949	Membrane
AB434_2500	COG4873	Protein conserved in bacteria
AB434_2503	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AB434_2506	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_2507	COG2084	Dehydrogenase
AB434_2510	COG0436	Aminotransferase
AB434_2511	COG0835	chemotaxis
AB434_2511	COG0784	Response regulator, receiver
AB434_2513	COG1033	growth of symbiont in host cell
AB434_2513	COG2409	Drug exporters of the RND superfamily
AB434_2516	COG5001	Diguanylate cyclase
AB434_2516	COG3300	MHYT domain
AB434_2520	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_2524	COG4703	Protein of unknown function (DUF1797)
AB434_2525	COG0517	IMP dehydrogenase activity
AB434_2526	COG0583	DNA-binding transcription factor activity
AB434_2527	COG2171	N-acyltransferase activity
AB434_2528	COG1473	amidohydrolase
AB434_2531	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AB434_2540	COG1982	Orn Lys Arg decarboxylase major
AB434_2542	COG4476	Belongs to the UPF0223 family
AB434_2545	COG0483	inositol monophosphate 1-phosphatase activity
AB434_2549	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AB434_2550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AB434_2551	COG4838	Belongs to the UPF0358 family
AB434_2552	COG0772	Belongs to the SEDS family
AB434_2553	COG1612	heme a metabolic process
AB434_2555	COG0109	protoheme IX farnesyltransferase activity
AB434_2556	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AB434_2556	COG2010	Cytochrome c
AB434_2559	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AB434_2560	COG3336	cytochrome c oxidase
AB434_2563	COG2340	Cysteine-rich secretory protein family
AB434_2564	COG2050	protein possibly involved in aromatic compounds catabolism
AB434_2568	COG3679	Belongs to the UPF0342 family
AB434_2572	COG0742	ribosomal rna small subunit methyltransferase
AB434_2573	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AB434_2576	COG3314	Sporulation integral membrane protein YlbJ
AB434_2577	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB434_2578	COG3480	Lon protease (S16) C-terminal proteolytic domain
AB434_2581	COG1323	Belongs to the UPF0348 family
AB434_2582	COG1399	metal-binding, possibly nucleic acid-binding protein
AB434_2583	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AB434_2585	COG0454	-acetyltransferase
AB434_2587	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AB434_2588	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AB434_2591	COG2001	Belongs to the MraZ family
AB434_2592	COG0275	rRNA processing
AB434_2593	COG4839	cell division protein FtsL
AB434_2596	COG0768	penicillin binding
AB434_2597	COG0768	penicillin binding
AB434_2601	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AB434_2602	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AB434_2603	COG0772	Belongs to the SEDS family
AB434_2604	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AB434_2605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AB434_2607	COG0849	cell division
AB434_2608	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AB434_2611	COG1191	sigma factor activity
AB434_2612	COG1191	sigma factor activity
AB434_2613	COG1873	PFAM PRC-barrel domain
AB434_2614	COG3584	3D domain protein
AB434_2614	COG1388	LysM domain
AB434_2616	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AB434_2617	COG1799	cell septum assembly
AB434_2618	COG0762	integral membrane protein
AB434_2619	COG2302	S4 RNA-binding domain
AB434_2620	COG3599	regulation of cell shape
AB434_2624	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AB434_2625	COG0564	pseudouridine synthase activity
AB434_2629	COG0540	Belongs to the ATCase OTCase family
AB434_2630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AB434_2634	COG0167	dihydroorotate dehydrogenase activity
AB434_2635	COG0284	orotidine-5'-phosphate decarboxylase activity
AB434_2636	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AB434_2642	COG1917	Cupin 2, conserved barrel domain protein
AB434_2642	COG2207	Transcriptional regulator
AB434_2643	COG1070	Carbohydrate kinase
AB434_2644	COG4806	L-rhamnose isomerase
AB434_2645	COG0235	Class ii aldolase
AB434_2647	COG1803	Methylglyoxal synthase
AB434_2650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AB434_2651	COG0477	Major facilitator Superfamily
AB434_2652	COG0477	Major facilitator Superfamily
AB434_2653	COG1309	transcriptional regulator
AB434_2655	COG2076	Multidrug Resistance protein
AB434_2657	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AB434_2658	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB434_2660	COG0628	permease
AB434_2661	COG0561	phosphatase activity
AB434_2664	COG3573	Dehydrogenase
AB434_2665	COG3573	Dehydrogenase
AB434_2672	COG0720	synthase
AB434_2674	COG0385	Bile acid
AB434_2676	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AB434_2677	COG1561	YicC-like family, N-terminal region
AB434_2678	COG2052	Domain of unknown function (DUF370)
AB434_2679	COG0194	GDP metabolic process
AB434_2681	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AB434_2682	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AB434_2683	COG0242	peptide deformylase activity
AB434_2684	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AB434_2685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AB434_2685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AB434_2686	COG0631	protein serine/threonine phosphatase activity
AB434_2687	COG0515	serine threonine protein kinase
AB434_2687	COG2815	serine threonine protein kinase
AB434_2689	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AB434_2690	COG1564	THIamine pyrophosphokinase
AB434_2692	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AB434_2693	COG1302	Protein conserved in bacteria
AB434_2694	COG1461	Dihydroxyacetone kinase
AB434_2696	COG1760	l-serine dehydratase
AB434_2697	COG1760	l-serine dehydratase
AB434_2698	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AB434_2699	COG2050	protein possibly involved in aromatic compounds catabolism
AB434_2699	COG1349	DNA-binding transcription factor activity
AB434_2701	COG0416	fatty acid biosynthetic process
AB434_2702	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AB434_2703	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_2704	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AB434_2705	COG0571	ribonuclease III activity
AB434_2706	COG1196	nuclear chromosome segregation
AB434_2708	COG0552	protein localization to endoplasmic reticulum
AB434_2711	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AB434_2712	COG0228	four-way junction DNA binding
AB434_2713	COG1837	Belongs to the UPF0109 family
AB434_2715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AB434_2716	COG0336	Belongs to the RNA methyltransferase TrmD family
AB434_2719	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AB434_2722	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AB434_2724	COG0045	succinate-CoA ligase (ADP-forming) activity
AB434_2725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AB434_2726	COG0758	DNA mediated transformation
AB434_2727	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AB434_2730	COG4974	Belongs to the 'phage' integrase family
AB434_2731	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AB434_2733	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AB434_2734	COG1815	bacterial-type flagellum-dependent cell motility
AB434_2735	COG1558	bacterial-type flagellum-dependent cell motility
AB434_2736	COG1677	Flagellar hook-basal body complex protein FliE
AB434_2737	COG1766	The M ring may be actively involved in energy transduction
AB434_2738	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AB434_2740	COG1317	bacterial-type flagellum organization
AB434_2741	COG1157	protein secretion by the type III secretion system
AB434_2742	COG2882	bacterial-type flagellum organization
AB434_2745	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AB434_2747	COG4786	Flagellar basal body rod
AB434_2749	COG1580	Controls the rotational direction of flagella during chemotaxis
AB434_2750	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AB434_2751	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AB434_2751	COG1776	CheC inhibitor of MCP methylation
AB434_2752	COG2201	protein-glutamate methylesterase activity
AB434_2753	COG3190	flagellar
AB434_2754	COG1338	Plays a role in the flagellum-specific transport system
AB434_2755	COG1987	bacterial-type flagellum assembly
AB434_2756	COG1684	flagellar biosynthetic protein fliR
AB434_2757	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AB434_2758	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AB434_2759	COG1419	protein localization to endoplasmic reticulum
AB434_2760	COG0455	bacterial-type flagellum organization
AB434_2761	COG2201	protein-glutamate methylesterase activity
AB434_2762	COG2198	Histidine kinase
AB434_2762	COG0643	Histidine kinase
AB434_2763	COG0835	chemotaxis
AB434_2764	COG1776	CheC inhibitor of MCP methylation
AB434_2765	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AB434_2766	COG1191	sigma factor activity
AB434_2768	COG0052	Belongs to the universal ribosomal protein uS2 family
AB434_2769	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AB434_2770	COG0528	UMP kinase activity
AB434_2771	COG0233	cytoplasmic translational termination
AB434_2773	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AB434_2774	COG4589	Belongs to the CDS family
AB434_2776	COG0750	zinc metalloprotease
AB434_2777	COG0442	prolyl-tRNA aminoacylation
AB434_2779	COG2176	DNA-directed DNA polymerase activity
AB434_2780	COG0779	Required for maturation of 30S ribosomal subunits
AB434_2781	COG0195	Participates in both transcription termination and antitermination
AB434_2782	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AB434_2783	COG1358	cellular component organization or biogenesis
AB434_2785	COG1550	Protein conserved in bacteria
AB434_2786	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AB434_2787	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AB434_2788	COG0196	riboflavin kinase activity
AB434_2789	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AB434_2790	COG1185	polyribonucleotide nucleotidyltransferase activity
AB434_2791	COG0726	polysaccharide deacetylase
AB434_2792	COG0612	Peptidase, M16
AB434_2793	COG1873	PFAM PRC-barrel domain
AB434_2795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AB434_2796	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AB434_2797	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AB434_2799	COG0527	aspartate kinase activity
AB434_2803	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AB434_2805	COG0740	serine-type endopeptidase activity
AB434_2807	COG4980	gas vesicle protein
AB434_2807	COG1674	ftsk spoiiie
AB434_2814	COG0612	Peptidase, M16
AB434_2815	COG0612	Peptidase, M16
AB434_2816	COG0300	oxidoreductase activity
AB434_2820	COG1426	Protein conserved in bacteria
AB434_2821	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AB434_2822	COG1546	Belongs to the CinA family
AB434_2822	COG1058	Belongs to the CinA family
AB434_2825	COG1418	mRNA catabolic process
AB434_2826	COG1692	metallophosphoesterase
AB434_2828	COG2359	stage V sporulation protein S
AB434_2831	COG0531	amino acid
AB434_2838	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB434_2839	COG4550	Control of competence regulator ComK, YlbF/YmcA
AB434_2841	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AB434_2842	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AB434_2847	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AB434_2850	COG0464	growth
AB434_2851	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AB434_2852	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AB434_2853	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB434_2858	COG1321	iron dependent repressor
AB434_2860	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AB434_2862	COG1418	mRNA catabolic process
AB434_2863	COG0488	(ABC) transporter
AB434_2864	COG1413	lyase activity
AB434_2868	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AB434_2869	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AB434_2870	COG1272	protein, Hemolysin III
AB434_2871	COG2755	lipolytic protein G-D-S-L family
AB434_2873	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AB434_2873	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AB434_2874	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB434_2875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB434_2877	COG0840	transmembrane signaling receptor activity
AB434_2878	COG4479	Belongs to the UPF0346 family
AB434_2883	COG1876	peptidase activity
AB434_2884	COG3409	Peptidoglycan-binding domain 1 protein
AB434_2884	COG0793	Belongs to the peptidase S41A family
AB434_2885	COG1846	Transcriptional regulator
AB434_2887	COG2340	Cysteine-rich secretory protein family
AB434_2888	COG0534	Mate efflux family protein
AB434_2890	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AB434_2891	COG3285	dna ligase
AB434_2891	COG1793	dna ligase
AB434_2892	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AB434_2893	COG0671	phosphoesterase, PA-phosphatase related
AB434_2895	COG1368	sulfuric ester hydrolase activity
AB434_2897	COG1331	Highly conserved protein containing a thioredoxin domain
AB434_2898	COG2814	Major facilitator Superfamily
AB434_2900	COG0745	RESPONSE REGULATOR receiver
AB434_2901	COG5002	protein histidine kinase activity
AB434_2904	COG0567	Dehydrogenase, E1 component
AB434_2906	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB434_2907	COG1012	belongs to the aldehyde dehydrogenase family
AB434_2909	COG0706	membrane insertase activity
AB434_2912	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB434_2916	COG2135	peptidase activity
AB434_2918	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB434_2919	COG0517	IMP dehydrogenase activity
AB434_2919	COG0516	GMP reductase activity
AB434_2920	COG0723	plastoquinol--plastocyanin reductase activity
AB434_2920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AB434_2921	COG1388	LysM domain
AB434_2921	COG3584	3D domain protein
AB434_2924	COG1113	amino acid transport
AB434_2925	COG1280	lysine exporter protein (LysE YggA)
AB434_2926	COG0598	Magnesium transport protein CorA
AB434_2928	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AB434_2929	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AB434_2930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AB434_2931	COG0131	Imidazoleglycerol-phosphate dehydratase
AB434_2932	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AB434_2934	COG0107	imidazoleglycerol-phosphate synthase activity
AB434_2935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AB434_2935	COG0140	phosphoribosyl-ATP diphosphatase activity
AB434_2937	COG2391	methyltransferase activity
AB434_2938	COG2962	Rard protein
AB434_2940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AB434_2941	COG0569	domain protein
AB434_2945	COG2807	transmembrane transport
AB434_2946	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AB434_2948	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AB434_2952	COG1278	Cold shock
AB434_2955	COG0302	gtp cyclohydrolase
AB434_2956	COG3634	alkyl hydroperoxide reductase activity
AB434_2959	COG0577	efflux transmembrane transporter activity
AB434_2960	COG1136	(ABC) transporter
AB434_2961	COG0642	Histidine kinase
AB434_2962	COG0745	RESPONSE REGULATOR receiver
AB434_2968	COG3328	transposase activity
AB434_2970	COG0640	Transcriptional regulator
AB434_2971	COG2814	Major facilitator Superfamily
AB434_2972	COG5039	Polysaccharide pyruvyl transferase
AB434_2974	COG1113	amino acid transport
AB434_2977	COG0477	Major facilitator Superfamily
AB434_2981	COG1132	(ABC) transporter
AB434_2983	COG1132	(ABC) transporter
AB434_2985	COG1380	Effector of murein hydrolase LrgA
AB434_2986	COG1346	cytolysis
AB434_2987	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_2992	COG2309	aminopeptidase activity
AB434_2994	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AB434_2998	COG0824	Thioesterase
AB434_3000	COG4841	protein insertion into membrane
AB434_3001	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AB434_3003	COG1832	CoA-binding protein
AB434_3005	COG0187	DNA topoisomerase II activity
AB434_3006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AB434_3009	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AB434_3010	COG0574	Belongs to the PEP-utilizing enzyme family
AB434_3010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AB434_3017	COG2070	2-Nitropropane dioxygenase
AB434_3020	COG0681	Belongs to the peptidase S26 family
AB434_3023	COG0473	3-isopropylmalate dehydrogenase activity
AB434_3027	COG2226	methyltransferase
AB434_3035	COG0456	acetyltransferase
AB434_3036	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AB434_3037	COG0456	acetyltransferase
AB434_3038	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_3039	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AB434_3040	COG0351	phosphomethylpyrimidine kinase
AB434_3043	COG2258	MOSC domain
AB434_3049	COG1309	transcriptional regulator
AB434_3050	COG2814	Major facilitator Superfamily
AB434_3053	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB434_3054	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB434_3056	COG1809	phosphosulfolactate synthase activity
AB434_3057	COG2045	Belongs to the ComB family
AB434_3058	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AB434_3059	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AB434_3061	COG0789	Transcriptional regulator
AB434_3062	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB434_3063	COG0697	spore germination
AB434_3065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AB434_3066	COG0022	dehydrogenase e1 component
AB434_3067	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB434_3068	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB434_3069	COG3284	Transcriptional regulator
AB434_3070	COG1511	domain protein
AB434_3070	COG3264	Mechanosensitive ion channel
AB434_3075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB434_3076	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AB434_3080	COG0183	Belongs to the thiolase family
AB434_3081	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_3084	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AB434_3085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB434_3086	COG2508	Transcriptional regulator
AB434_3087	COG2233	PERMEase
AB434_3089	COG2072	flavoprotein involved in K transport
AB434_3091	COG0561	phosphatase activity
AB434_3092	COG2322	membrane
AB434_3095	COG0039	L-malate dehydrogenase activity
AB434_3096	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_3097	COG2223	nitrite transmembrane transporter activity
AB434_3098	COG3773	Cell wall hydrolase
AB434_3099	COG0708	Exodeoxyribonuclease III
AB434_3102	COG0297	glycogen (starch) synthase activity
AB434_3103	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AB434_3104	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AB434_3105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AB434_3111	COG1247	-acetyltransferase
AB434_3113	COG0494	nUDIX hydrolase
AB434_3114	COG1914	H( )-stimulated, divalent metal cation uptake system
AB434_3115	COG0783	Belongs to the Dps family
AB434_3117	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AB434_3118	COG1131	(ABC) transporter
AB434_3124	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AB434_3126	COG2030	dehydratase
AB434_3127	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_3129	COG0277	FAD linked oxidase domain protein
AB434_3131	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AB434_3132	COG0709	Synthesizes selenophosphate from selenide and ATP
AB434_3135	COG0701	Predicted permease
AB434_3136	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AB434_3137	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AB434_3140	COG1252	NADH dehydrogenase
AB434_3142	COG2404	hydrolase activity, acting on ester bonds
AB434_3144	COG4990	cell redox homeostasis
AB434_3145	COG0789	Transcriptional regulator
AB434_3150	COG0436	Aminotransferase
AB434_3151	COG0165	Argininosuccinate lyase
AB434_3152	COG0137	argininosuccinate synthase activity
AB434_3153	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AB434_3154	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AB434_3155	COG0505	Belongs to the CarA family
AB434_3156	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AB434_3157	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AB434_3158	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AB434_3159	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AB434_3162	COG3546	catalase activity
AB434_3168	COG1619	proteins homologs of microcin C7 resistance protein MccF
AB434_3169	COG2027	D-alanyl-D-alanine carboxypeptidase
AB434_3170	COG0204	Acyl-transferase
AB434_3173	COG4846	Membrane protein involved in cytochrome C biogenesis
AB434_3174	COG2201	protein-glutamate methylesterase activity
AB434_3175	COG0785	Cytochrome C biogenesis protein
AB434_3176	COG3763	UPF0154 protein
AB434_3179	COG4224	UPF0291 protein
AB434_3180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AB434_3182	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AB434_3185	COG1388	LysM domain
AB434_3185	COG0791	NLP P60 protein
AB434_3195	COG3953	SLT domain
AB434_3195	COG5280	Phage tail tape measure protein TP901
AB434_3204	COG0740	serine-type endopeptidase activity
AB434_3211	COG0582	viral genome integration into host DNA
AB434_3212	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AB434_3220	COG0629	single-stranded DNA binding
AB434_3227	COG1396	sequence-specific DNA binding
AB434_3229	COG2176	DNA-directed DNA polymerase activity
AB434_3232	COG0582	viral genome integration into host DNA
AB434_3233	COG0174	glutamine synthetase
AB434_3234	COG0789	Transcriptional regulator
AB434_3235	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AB434_3238	COG2233	PERMEase
AB434_3240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AB434_3241	COG0116	Belongs to the methyltransferase superfamily
AB434_3246	COG4474	Belongs to the UPF0398 family
AB434_3249	COG3359	exonuclease
AB434_3250	COG1205	dead DEAH box helicase
AB434_3250	COG1111	helicase
AB434_3251	COG0071	Belongs to the small heat shock protein (HSP20) family
AB434_3258	COG3331	DNA recombination
AB434_3259	COG4499	WXG100 protein secretion system (Wss), protein YukC
AB434_3259	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AB434_3260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AB434_3261	COG3935	DnaD domain protein
AB434_3262	COG3344	reverse transcriptase
AB434_3263	COG0017	Asparaginyl-tRNA synthetase
AB434_3266	COG1199	ATP-dependent helicase activity
AB434_3266	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AB434_3267	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AB434_3268	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AB434_3272	COG0438	transferase activity, transferring glycosyl groups
AB434_3273	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AB434_3274	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AB434_3275	COG1694	Mazg nucleotide pyrophosphohydrolase
AB434_3276	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AB434_3278	COG2738	Putative neutral zinc metallopeptidase
AB434_3280	COG4347	Protein of unknown function (DUF1405)
AB434_3282	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AB434_3285	COG5582	Belongs to the UPF0302 family
AB434_3286	COG0457	Tetratricopeptide repeat
AB434_3289	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AB434_3290	COG0287	Prephenate dehydrogenase
AB434_3291	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AB434_3292	COG4401	Chorismate mutase type I
AB434_3293	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AB434_3294	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AB434_3295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB434_3296	COG0105	UTP biosynthetic process
AB434_3297	COG0142	geranyltranstransferase activity
AB434_3298	COG2226	methyltransferase
AB434_3299	COG0142	geranyltranstransferase activity
AB434_3302	COG0776	regulation of translation
AB434_3303	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AB434_3307	COG1160	GTP binding
AB434_3310	COG0539	negative regulation of cytoplasmic translation
AB434_3311	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AB434_3312	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AB434_3313	COG2959	enzyme of heme biosynthesis
AB434_3314	COG3773	Cell wall hydrolase
AB434_3314	COG3409	Peptidoglycan-binding domain 1 protein
AB434_3315	COG2339	peptidase activity
AB434_3316	COG0492	ferredoxin-NADP+ reductase activity
AB434_3318	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AB434_3321	COG1408	metallophosphoesterase
AB434_3325	COG3546	catalase activity
AB434_3328	COG1266	CAAX protease self-immunity
AB434_3329	COG0514	ATP-dependent DNA helicase (RecQ)
AB434_3332	COG1141	Ferredoxin
AB434_3333	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AB434_3334	COG1196	nuclear chromosome segregation
AB434_3334	COG0741	lytic transglycosylase activity
AB434_3334	COG0739	heme binding
AB434_3335	COG5002	protein histidine kinase activity
AB434_3336	COG0745	RESPONSE REGULATOR receiver
AB434_3338	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB434_3339	COG1333	cytochrome c biogenesis protein
AB434_3340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB434_3341	COG1187	pseudouridine synthase activity
AB434_3342	COG0700	Nucleoside recognition
AB434_3343	COG2715	membrane protein required for spore maturation
AB434_3344	COG1686	Belongs to the peptidase S11 family
AB434_3345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AB434_3350	COG0697	spore germination
AB434_3355	COG1191	sigma factor activity
AB434_3358	COG1686	Belongs to the peptidase S11 family
AB434_3361	COG4974	Belongs to the 'phage' integrase family
AB434_3363	COG0735	belongs to the Fur family
AB434_3364	COG1300	Membrane
AB434_3365	COG1379	DNA repair
AB434_3368	COG0667	Aldo Keto reductase
AB434_3371	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AB434_3372	COG3853	Toxic anion resistance protein (TelA)
AB434_3374	COG1073	alpha beta
AB434_3375	COG1388	LysM domain
AB434_3375	COG3858	chitin binding
AB434_3378	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB434_3379	COG0300	oxidoreductase activity
AB434_3381	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AB434_3383	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AB434_3384	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AB434_3386	COG2195	Cleaves the N-terminal amino acid of tripeptides
AB434_3388	COG1376	ErfK ybiS ycfS ynhG family protein
AB434_3391	COG1105	Belongs to the carbohydrate kinase PfkB family
AB434_3392	COG0508	dehydrogenase complex catalyzes the overall conversion of
AB434_3393	COG0022	dehydrogenase e1 component
AB434_3394	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AB434_3395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AB434_3397	COG3829	transcription factor binding
AB434_3397	COG3290	protein histidine kinase activity
AB434_3398	COG3290	protein histidine kinase activity
AB434_3398	COG3829	transcription factor binding
AB434_3400	COG0584	glycerophosphoryl diester phosphodiesterase
AB434_3401	COG0745	RESPONSE REGULATOR receiver
AB434_3402	COG0750	zinc metalloprotease
AB434_3403	COG0497	DNA recombination
AB434_3405	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AB434_3406	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AB434_3409	COG1570	exodeoxyribonuclease VII activity
AB434_3413	COG1302	Protein conserved in bacteria
AB434_3414	COG0439	Biotin carboxylase
AB434_3415	COG0511	ligase activity, forming carbon-carbon bonds
AB434_3424	COG3854	ATPases associated with a variety of cellular activities
AB434_3425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AB434_3426	COG0006	proline dipeptidase activity
AB434_3429	COG3872	metal-dependent enzyme
AB434_3431	COG1752	Esterase of the alpha-beta hydrolase superfamily
AB434_3433	COG3327	negative regulation of DNA-templated transcription, initiation
AB434_3434	COG0183	Belongs to the thiolase family
AB434_3435	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_3436	COG1012	belongs to the aldehyde dehydrogenase family
AB434_3437	COG1024	Enoyl-CoA hydratase
AB434_3438	COG0492	ferredoxin-NADP+ reductase activity
AB434_3440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AB434_3442	COG0095	Lipoate-protein ligase
AB434_3444	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB434_3445	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AB434_3447	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AB434_3450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AB434_3453	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AB434_3458	COG4537	Required for transformation and DNA binding
AB434_3459	COG1459	type II secretion system
AB434_3460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB434_3463	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB434_3465	COG1940	carbohydrate kinase activity
AB434_3466	COG4483	Protein conserved in bacteria
AB434_3468	COG0457	Tetratricopeptide repeat
AB434_3468	COG0705	Rhomboid family
AB434_3471	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AB434_3474	COG0477	Major facilitator Superfamily
AB434_3476	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AB434_3478	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AB434_3479	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AB434_3480	COG0735	belongs to the Fur family
AB434_3481	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AB434_3482	COG1121	(ABC) transporter
AB434_3485	COG0791	NLP P60 protein
AB434_3485	COG3883	PFAM NLP P60 protein
AB434_3486	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AB434_3487	COG0513	Belongs to the DEAD box helicase family
AB434_3491	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AB434_3492	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AB434_3493	COG2384	SAM-dependent methyltransferase
AB434_3494	COG2010	Cytochrome c
AB434_3497	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AB434_3498	COG0358	DNA primase activity
AB434_3501	COG0517	IMP dehydrogenase activity
AB434_3503	COG1381	Involved in DNA repair and RecF pathway recombination
AB434_3506	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AB434_3507	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AB434_3508	COG1480	7TM receptor with intracellular HD hydrolase
AB434_3510	COG1702	phosphate starvation-inducible protein PhoH
AB434_3514	COG1610	YqeY-like protein
AB434_3517	COG1283	sodium-dependent phosphate transmembrane transporter activity
AB434_3518	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AB434_3519	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AB434_3520	COG2264	protein methyltransferase activity
AB434_3522	COG0443	Heat shock 70 kDa protein
AB434_3523	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AB434_3525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AB434_3526	COG0481	GTPase activity
AB434_3527	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB434_3528	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AB434_3530	COG0268	Binds directly to 16S ribosomal RNA
AB434_3531	COG1466	dna polymerase III delta subunit
AB434_3533	COG0658	competence protein
AB434_3533	COG2333	competence protein COMEC
AB434_3534	COG2131	deaminase
AB434_3535	COG1555	photosystem II stabilization
AB434_3535	COG1596	polysaccharide export
AB434_3536	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AB434_3537	COG2226	methyltransferase
AB434_3538	COG0799	negative regulation of ribosome biogenesis
AB434_3539	COG1713	HD superfamily hydrolase involved in NAD metabolism
AB434_3540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AB434_3541	COG1534	Rna-binding protein
AB434_3543	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AB434_3544	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AB434_3545	COG0247	lactate metabolic process
AB434_3546	COG0277	FAD linked oxidase domain protein
AB434_3547	COG0277	FAD linked oxidase domain protein
AB434_3548	COG3835	regulator
AB434_3549	COG2132	Multicopper oxidase
AB434_3550	COG0071	Belongs to the small heat shock protein (HSP20) family
AB434_3552	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB434_3556	COG1704	LemA family
AB434_3564	COG1183	phosphatidylcholine synthase activity
AB434_3568	COG3634	alkyl hydroperoxide reductase activity
AB434_3569	COG0450	alkyl hydroperoxide reductase
AB434_3576	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AB434_3577	COG0572	uridine kinase
AB434_3579	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AB434_3580	COG3906	Belongs to the UPF0473 family
AB434_3581	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AB434_3582	COG4472	Bacterial protein of unknown function (DUF965)
AB434_3583	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AB434_3584	COG0628	permease
AB434_3594	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AB434_3597	COG0482	sulfurtransferase activity
AB434_3598	COG1104	cysteine desulfurase activity
AB434_3599	COG1959	2 iron, 2 sulfur cluster binding
AB434_3601	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_3603	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AB434_3604	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AB434_3605	COG0385	Bile acid
AB434_3607	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AB434_3608	COG0124	histidyl-tRNA synthetase
AB434_3610	COG0860	N-Acetylmuramoyl-L-alanine amidase
AB434_3610	COG3103	Sh3 type 3 domain protein
AB434_3610	COG4991	sh3 domain protein
AB434_3611	COG2814	Major facilitator Superfamily
AB434_3612	COG1566	PFAM secretion protein HlyD family protein
AB434_3613	COG1846	Transcriptional regulator
AB434_3614	COG1490	D-aminoacyl-tRNA deacylase activity
AB434_3615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AB434_3616	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AB434_3617	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AB434_3617	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AB434_3619	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB434_3619	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AB434_3621	COG2244	polysaccharide biosynthetic process
AB434_3622	COG2323	membrane
AB434_3624	COG1862	Preprotein translocase
AB434_3625	COG0343	queuine tRNA-ribosyltransferase activity
AB434_3626	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AB434_3629	COG0632	four-way junction helicase activity
AB434_3631	COG0217	transcriptional regulatory protein
AB434_3633	COG1388	LysM domain
AB434_3634	COG1827	regulation of RNA biosynthetic process
AB434_3635	COG0077	Prephenate dehydratase
AB434_3636	COG4492	Belongs to the UPF0735 family
AB434_3637	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AB434_3638	COG3290	protein histidine kinase activity
AB434_3639	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AB434_3640	COG2868	ribosomal protein
AB434_3641	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AB434_3642	COG1530	ribonuclease E activity
AB434_3643	COG1994	Peptidase M50
AB434_3645	COG2894	cell division
AB434_3646	COG0850	regulation of cytokinetic process
AB434_3649	COG1792	Involved in formation and maintenance of cell shape
AB434_3650	COG1077	Cell shape determining protein MreB Mrl
AB434_3651	COG2003	Belongs to the UPF0758 family
AB434_3654	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AB434_3659	COG1459	type II secretion system
AB434_3661	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AB434_3668	COG0285	dihydrofolate synthase activity
AB434_3669	COG0525	valine-tRNA ligase activity
AB434_3671	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AB434_3672	COG1388	LysM domain
AB434_3672	COG1388	LysM domain
AB434_3674	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AB434_3675	COG0113	porphobilinogen synthase activity
AB434_3677	COG0181	hydroxymethylbilane synthase activity
AB434_3678	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AB434_3681	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AB434_3682	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AB434_3683	COG1067	ATP-dependent peptidase activity
AB434_3683	COG0470	DNA polymerase III
AB434_3685	COG0544	peptidyl-prolyl cis-trans isomerase activity
AB434_3686	COG1477	protein flavinylation
AB434_3686	COG0457	Tetratricopeptide repeat
AB434_3695	COG0622	Phosphoesterase
AB434_3696	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AB434_3697	COG5401	PFAM Sporulation and spore germination
AB434_3699	COG5577	PFAM Coat F domain
AB434_3700	COG1063	alcohol dehydrogenase
AB434_3701	COG5577	PFAM Coat F domain
AB434_3704	COG1846	Transcriptional regulator
AB434_3713	COG2197	response regulator
AB434_3714	COG0824	Thioesterase
AB434_3715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AB434_3716	COG1053	succinate dehydrogenase
AB434_3717	COG2009	succinate dehydrogenase
AB434_3719	COG1719	4-vinyl reductase, 4VR
AB434_3722	COG0322	excinuclease ABC activity
AB434_3723	COG3118	belongs to the thioredoxin family
AB434_3726	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AB434_3727	COG2086	electron transfer activity
AB434_3728	COG1024	Enoyl-CoA hydratase
AB434_3729	COG1309	transcriptional regulator
AB434_3730	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_3732	COG1193	negative regulation of DNA recombination
AB434_3733	COG1796	DNA polymerase
AB434_3733	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AB434_3735	COG1286	toxin biosynthetic process
AB434_3736	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AB434_3738	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB434_3738	COG0072	phenylalanine-tRNA ligase activity
AB434_3739	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AB434_3742	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AB434_3750	COG2329	Antibiotic biosynthesis monooxygenase
AB434_3752	COG1695	Transcriptional regulator
AB434_3757	COG0431	NADPH-dependent FMN reductase
AB434_3766	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AB434_3767	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AB434_3768	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AB434_3771	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AB434_3774	COG1484	DNA-dependent DNA replication
AB434_3775	COG3611	Membrane attachment protein
AB434_3776	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AB434_3777	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AB434_3778	COG0237	dephospho-CoA kinase activity
AB434_3779	COG1971	Probably functions as a manganese efflux pump
AB434_3780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AB434_3781	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB434_3781	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AB434_3783	COG0039	L-malate dehydrogenase activity
AB434_3784	COG0538	isocitrate dehydrogenase activity
AB434_3785	COG0372	Belongs to the citrate synthase family
AB434_3787	COG2707	UPF0756 membrane protein
AB434_3788	COG0628	permease
AB434_3790	COG0205	6-phosphofructokinase activity
AB434_3792	COG0825	malonyl-CoA metabolic process
AB434_3793	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AB434_3794	COG0281	malic enzyme
AB434_3795	COG0587	DNA-directed DNA polymerase activity
AB434_3798	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AB434_3800	COG4109	DRTGG domain
AB434_3801	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AB434_3802	COG0006	proline dipeptidase activity
AB434_3805	COG0589	response to stress
AB434_3808	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AB434_3810	COG0827	DNA restriction-modification system
AB434_3811	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AB434_3812	COG3874	Sporulation protein YtfJ
AB434_3814	COG1714	RDD family
AB434_3815	COG0616	signal peptide processing
AB434_3816	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB434_3818	COG0301	tRNA thio-modification
AB434_3819	COG1104	cysteine desulfurase activity
AB434_3820	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AB434_3821	COG1309	transcriptional regulator
AB434_3822	COG1956	GAF domain-containing protein
AB434_3823	COG2203	Gaf domain
AB434_3823	COG2199	diguanylate cyclase activity
AB434_3826	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AB434_3828	COG0506	proline dehydrogenase activity
AB434_3829	COG1012	belongs to the aldehyde dehydrogenase family
AB434_3831	COG3290	protein histidine kinase activity
AB434_3831	COG3829	transcription factor binding
AB434_3835	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AB434_3837	COG3383	formate dehydrogenase (NAD+) activity
AB434_3838	COG2427	Protein of unknown function (DUF1641)
AB434_3839	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AB434_3840	COG0315	cyclic pyranopterin monophosphate synthase activity
AB434_3841	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AB434_3842	COG0314	molybdopterin synthase activity
AB434_3843	COG1763	Mo-molybdopterin cofactor biosynthetic process
AB434_3844	COG0303	'Molybdopterin
AB434_3847	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AB434_3849	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AB434_3850	COG4149	molybdate abc transporter
AB434_3852	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AB434_3854	COG0454	-acetyltransferase
AB434_3855	COG0517	IMP dehydrogenase activity
AB434_3856	COG0123	including yeast histone deacetylase and acetoin utilization protein
AB434_3858	COG1605	Chorismate mutase
AB434_3858	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AB434_3860	COG4980	gas vesicle protein
AB434_3862	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AB434_3865	COG1674	ftsk spoiiie
AB434_3867	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AB434_3868	COG4848	Belongs to the UPF0354 family
AB434_3870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB434_3871	COG2208	phosphoserine phosphatase activity
AB434_3872	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AB434_3873	COG5002	protein histidine kinase activity
AB434_3873	COG0784	Response regulator, receiver
AB434_3876	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AB434_3877	COG1363	Peptidase, m42
AB434_3878	COG5584	Small secreted protein
AB434_3880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AB434_3882	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AB434_3884	COG0510	thiamine kinase activity
AB434_3891	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AB434_3893	COG1349	DNA-binding transcription factor activity
AB434_3894	COG2244	polysaccharide biosynthetic process
AB434_3898	COG0495	leucyl-tRNA aminoacylation
AB434_3899	COG2814	Major facilitator Superfamily
AB434_3903	COG0275	rRNA processing
AB434_3907	COG2267	carboxylic ester hydrolase activity
AB434_3908	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AB434_3910	COG0367	asparagine synthase
AB434_3911	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AB434_3912	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AB434_3915	COG1506	peptidase
AB434_3916	COG0655	NAD(P)H dehydrogenase (quinone) activity
AB434_3917	COG1070	Carbohydrate kinase
AB434_3918	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AB434_3919	COG1116	anion transmembrane transporter activity
AB434_3920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AB434_3923	COG0783	Belongs to the Dps family
AB434_3924	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AB434_3926	COG0803	Belongs to the bacterial solute-binding protein 9 family
AB434_3928	COG4948	Mandelate Racemase Muconate Lactonizing
AB434_3929	COG0318	PFAM AMP-dependent synthetase and ligase
AB434_3931	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AB434_3932	COG0596	Alpha beta hydrolase
AB434_3933	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AB434_3934	COG1169	isochorismate synthase
AB434_3935	COG1575	Belongs to the MenA family. Type 1 subfamily
AB434_3937	COG1285	pathogenesis
AB434_3942	COG2217	Heavy metal translocating P-type atpase
AB434_3943	COG2608	mercury ion transmembrane transporter activity
AB434_3946	COG1522	sequence-specific DNA binding
AB434_3950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AB434_3955	COG0726	polysaccharide deacetylase
AB434_3959	COG3328	transposase activity
AB434_3961	COG0038	chloride channel
AB434_3963	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AB434_3964	COG1937	Protein conserved in bacteria
AB434_3966	COG1525	nuclease
AB434_3967	COG2190	(PTS) system
AB434_3971	COG2160	L-arabinose isomerase activity
AB434_3972	COG1609	Transcriptional regulator
AB434_3973	COG4213	ABC transporter substrate-binding protein
AB434_3975	COG4214	carbohydrate transport
AB434_3976	COG2160	L-arabinose isomerase activity
AB434_3978	COG1609	Transcriptional regulator
AB434_3979	COG0840	transmembrane signaling receptor activity
AB434_3984	COG1028	Short-chain dehydrogenase reductase Sdr
AB434_3986	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AB434_3991	COG1012	belongs to the aldehyde dehydrogenase family
AB434_3995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AB434_3997	COG2155	Conserved Protein
AB434_4002	COG1098	S1 RNA binding domain
AB434_4005	COG0656	L-ascorbic acid biosynthetic process
AB434_4011	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AB434_4018	COG2814	Major facilitator Superfamily
AB434_4019	COG2050	protein possibly involved in aromatic compounds catabolism
AB434_4023	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AB434_4025	COG0697	spore germination
AB434_4027	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AB434_4028	COG3584	3D domain protein
AB434_4031	COG1252	NADH dehydrogenase
AB434_4032	COG0492	ferredoxin-NADP+ reductase activity
AB434_4038	COG0316	Belongs to the HesB IscA family
AB434_4040	COG4837	Protein of unknown function (DUF1462)
AB434_4041	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AB434_4042	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AB434_4043	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AB434_4044	COG0647	UMP catabolic process
AB434_4045	COG2445	Protein of unknown function DUF86
AB434_4046	COG4470	Protein conserved in bacteria
AB434_4048	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AB434_4050	COG0739	heme binding
AB434_4052	COG3377	Domain of unknown function (DUF1805)
AB434_4053	COG0737	Belongs to the 5'-nucleotidase family
AB434_4055	COG0719	Fe-S assembly protein
AB434_4056	COG0822	iron-sulfur transferase activity
AB434_4057	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AB434_4058	COG0719	Fe-S assembly protein
AB434_4059	COG0396	ATPase activity
AB434_4062	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB434_4063	COG0509	glycine decarboxylation via glycine cleavage system
AB434_4064	COG1393	Belongs to the ArsC family
AB434_4065	COG1960	acyl-CoA dehydrogenase activity
AB434_4066	COG0183	Belongs to the thiolase family
AB434_4067	COG1024	Enoyl-CoA hydratase
AB434_4067	COG1250	3-hydroxyacyl-CoA dehydrogenase
AB434_4070	COG5577	PFAM Coat F domain
AB434_4071	COG0772	Belongs to the SEDS family
AB434_4072	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AB434_4075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AB434_4076	COG2202	Pas domain
AB434_4076	COG2200	EAL domain
AB434_4076	COG2199	diguanylate cyclase activity
AB434_4077	COG0753	catalase activity
AB434_4079	COG0671	phosphoesterase, PA-phosphatase related
AB434_4082	COG0726	polysaccharide deacetylase
AB434_4083	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)