locus-tag	class	description
CG481_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG481_000010	COG0592	DNA-directed DNA polymerase activity
CG481_000015	COG2501	S4 domain
CG481_000020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG481_000025	COG0187	DNA topoisomerase II activity
CG481_000030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG481_000065	COG0516	GMP reductase activity
CG481_000065	COG0517	IMP dehydrogenase activity
CG481_000070	COG1686	Belongs to the peptidase S11 family
CG481_000075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CG481_000080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CG481_000085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG481_000100	COG1428	Deoxynucleoside kinase
CG481_000105	COG1428	Deoxynucleoside kinase
CG481_000110	COG1335	isochorismatase
CG481_000115	COG0590	tRNA wobble adenosine to inosine editing
CG481_000125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG481_000130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG481_000135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG481_000180	COG1982	Orn Lys Arg decarboxylase major
CG481_000185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG481_000190	COG0470	DNA polymerase III
CG481_000195	COG1774	PSP1 C-terminal conserved region
CG481_000200	COG4467	Involved in initiation control of chromosome replication
CG481_000205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CG481_000215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CG481_000220	COG2002	toxin-antitoxin pair type II binding
CG481_000230	COG0084	hydrolase, TatD family'
CG481_000240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG481_000250	COG4466	Protein conserved in bacteria
CG481_000260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CG481_000265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG481_000270	COG0251	oxidation-reduction process
CG481_000275	COG2088	sporulation resulting in formation of a cellular spore
CG481_000280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG481_000285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CG481_000290	COG0193	aminoacyl-tRNA hydrolase activity
CG481_000300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG481_000305	COG2002	toxin-antitoxin pair type II binding
CG481_000310	COG2244	polysaccharide biosynthetic process
CG481_000315	COG3956	TIGRFAM MazG family protein
CG481_000320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CG481_000340	COG1098	S1 RNA binding domain
CG481_000370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG481_000375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CG481_000380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG481_000385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG481_000395	COG0512	Glutamine amidotransferase of anthranilate synthase
CG481_000400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG481_000405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CG481_000410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CG481_000415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CG481_000420	COG1396	sequence-specific DNA binding
CG481_000425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG481_000430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG481_000465	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG481_000515	COG3880	PFAM UvrB UvrC protein
CG481_000520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CG481_000525	COG0542	response to heat
CG481_000530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CG481_000545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG481_000550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG481_000555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG481_000560	COG1045	serine acetyltransferase
CG481_000565	COG0215	cysteine-tRNA ligase activity
CG481_000575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG481_000580	COG3688	RNA-binding protein containing a PIN domain
CG481_000600	COG0250	Participates in transcription elongation, termination and antitermination
CG481_000610	COG0081	regulation of translation
CG481_000615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG481_000620	COG0222	ribosome binding
CG481_000625	COG2813	Specifically methylates the guanine in position
CG481_000635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG481_000640	COG1358	cellular component organization or biogenesis
CG481_000645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CG481_000650	COG0049	tRNA binding
CG481_000655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG481_000660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG481_000670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CG481_000675	COG0088	Forms part of the polypeptide exit tunnel
CG481_000680	COG0089	rRNA binding
CG481_000685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CG481_000690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG481_000695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CG481_000700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CG481_000705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CG481_000715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG481_000720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG481_000725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CG481_000730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CG481_000740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG481_000745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CG481_000750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CG481_000755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CG481_000760	COG1841	ribosomal large subunit assembly
CG481_000765	COG0200	Binds to the 23S rRNA
CG481_000770	COG0201	protein transport
CG481_000775	COG0563	adenylate kinase activity
CG481_000780	COG0024	Methionine aminopeptidase
CG481_000790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG481_000800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG481_000805	COG0202	RNA polymerase activity
CG481_000820	COG1122	ATPase activity
CG481_000825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG481_000835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG481_000840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CG481_000850	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG481_000855	COG0489	protein tyrosine kinase activity
CG481_000865	COG2194	sulfuric ester hydrolase activity
CG481_000870	COG0726	polysaccharide deacetylase
CG481_000950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CG481_000960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG481_001025	COG0457	Tetratricopeptide repeat
CG481_001050	COG1266	CAAX protease self-immunity
CG481_001125	COG3681	Belongs to the UPF0597 family
CG481_001130	COG3681	Belongs to the UPF0597 family
CG481_001155	COG2814	Major facilitator Superfamily
CG481_001165	COG0601	transmembrane transport
CG481_001170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG481_001175	COG0444	Belongs to the ABC transporter superfamily
CG481_001180	COG4608	Belongs to the ABC transporter superfamily
CG481_001185	COG4166	transmembrane transport
CG481_001205	COG1309	transcriptional regulator
CG481_001215	COG0656	L-ascorbic acid biosynthetic process
CG481_001230	COG4149	molybdate abc transporter
CG481_001235	COG0725	ABC transporter, periplasmic molybdate-binding protein
CG481_001240	COG1910	domain protein
CG481_001245	COG0204	Acyl-transferase
CG481_001250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG481_001255	COG1648	precorrin-2 dehydrogenase activity
CG481_001255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG481_001265	COG1587	Uroporphyrinogen-III synthase
CG481_001265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG481_001270	COG2146	nitrite reductase [NAD(P)H] activity
CG481_001275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG481_001305	COG4585	Histidine kinase
CG481_001310	COG2197	response regulator
CG481_001315	COG1131	(ABC) transporter
CG481_001320	COG0842	Transport permease protein
CG481_001320	COG1511	domain protein
CG481_001325	COG0842	Transport permease protein
CG481_001335	COG0747	negative chemotaxis
CG481_001340	COG0601	transmembrane transport
CG481_001345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG481_001350	COG0444	Belongs to the ABC transporter superfamily
CG481_001355	COG4608	Belongs to the ABC transporter superfamily
CG481_001360	COG0561	phosphatase activity
CG481_001380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CG481_001385	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG481_001395	COG2814	Major facilitator Superfamily
CG481_001400	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG481_001405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CG481_001415	COG0705	Rhomboid family
CG481_001415	COG0457	Tetratricopeptide repeat
CG481_001420	COG0736	holo-[acyl-carrier-protein] synthase activity
CG481_001425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG481_001435	COG0864	Transcriptional regulator
CG481_001440	COG2337	Toxic component of a toxin-antitoxin (TA) module
CG481_001445	COG2183	response to ionizing radiation
CG481_001455	COG3091	SprT-like family
CG481_001495	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG481_001545	COG0802	atpase or kinase
CG481_001550	COG1214	PFAM Peptidase M22, glycoprotease
CG481_001555	COG0456	acetyltransferase
CG481_001565	COG0488	(ABC) transporter
CG481_001570	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CG481_001580	COG1266	CAAX protease self-immunity
CG481_001585	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CG481_001590	COG0459	protein refolding
CG481_001595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG481_001595	COG0519	Catalyzes the synthesis of GMP from XMP
CG481_001600	COG2252	PERMEase
CG481_001610	COG5002	protein histidine kinase activity
CG481_001680	COG2205	protein histidine kinase activity
CG481_001685	COG0745	RESPONSE REGULATOR receiver
CG481_001705	COG0697	spore germination
CG481_001730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG481_001735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG481_001740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG481_001745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG481_001750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG481_001755	COG0047	phosphoribosylformylglycinamidine synthase activity
CG481_001760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG481_001765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CG481_001770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG481_001775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG481_001780	COG0138	bifunctional purine biosynthesis protein purh
CG481_001785	COG0151	Belongs to the GarS family
CG481_001795	COG0583	DNA-binding transcription factor activity
CG481_001815	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CG481_001820	COG0210	DNA helicase
CG481_001825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CG481_001830	COG4851	CamS sex pheromone cAM373 precursor
CG481_001840	COG1012	belongs to the aldehyde dehydrogenase family
CG481_001845	COG1335	isochorismatase
CG481_001855	COG2011	ABC-type metal ion transport system permease component
CG481_001875	COG4682	membrane
CG481_001880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG481_001885	COG0154	amidase activity
CG481_001890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG481_001895	COG1597	lipid kinase activity
CG481_001900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG481_001905	COG0546	phosphoglycolate phosphatase activity
CG481_001910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG481_001925	COG1012	belongs to the aldehyde dehydrogenase family
CG481_001930	COG2076	Multidrug Resistance protein
CG481_001935	COG2309	aminopeptidase activity
CG481_001945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG481_001950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG481_001955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG481_001970	COG0450	alkyl hydroperoxide reductase
CG481_002030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG481_002035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG481_002040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG481_002045	COG0492	ferredoxin-NADP+ reductase activity
CG481_002055	COG0166	Belongs to the GPI family
CG481_002060	COG5002	protein histidine kinase activity
CG481_002090	COG2814	Major facilitator Superfamily
CG481_002095	COG0723	plastoquinol--plastocyanin reductase activity
CG481_002095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG481_002105	COG0765	amino acid transport
CG481_002110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG481_002115	COG1126	abc transporter atp-binding protein
CG481_002120	COG0840	transmembrane signaling receptor activity
CG481_002130	COG2235	arginine
CG481_002145	COG0549	Belongs to the carbamate kinase family
CG481_002160	COG0366	Alpha amylase catalytic
CG481_002165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG481_002165	COG1263	PTS System
CG481_002165	COG2190	(PTS) system
CG481_002185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG481_002190	COG4605	iron ion homeostasis
CG481_002195	COG4604	ABC transporter, ATP-binding protein
CG481_002200	COG4607	ABC-type enterochelin transport system periplasmic component
CG481_002205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CG481_002210	COG0352	thiamine-phosphate diphosphorylase activity
CG481_002215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CG481_002235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG481_002245	COG1116	anion transmembrane transporter activity
CG481_002280	COG2270	Major facilitator Superfamily
CG481_002305	COG2310	stress, protein
CG481_002310	COG2310	stress, protein
CG481_002315	COG2310	stress, protein
CG481_002320	COG0861	Integral membrane protein TerC family
CG481_002330	COG3853	Toxic anion resistance protein (TelA)
CG481_002340	COG4840	Belongs to the UPF0435 family
CG481_002345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG481_002355	COG1295	ribonuclease BN
CG481_002360	COG2217	Heavy metal translocating P-type atpase
CG481_002365	COG0697	spore germination
CG481_002375	COG0681	Belongs to the peptidase S26 family
CG481_002385	COG0586	Pfam SNARE associated Golgi protein
CG481_002400	COG0387	Pfam Sodium calcium exchanger
CG481_002410	COG0535	radical SAM domain protein
CG481_002430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CG481_002465	COG2066	Belongs to the glutaminase family
CG481_002470	COG1263	PTS System
CG481_002470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG481_002485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG481_002485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG481_002495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CG481_002500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG481_002515	COG0402	S-adenosylhomocysteine deaminase activity
CG481_002520	COG2137	regulation of response to DNA damage stimulus
CG481_002545	COG1988	membrane-bound metal-dependent
CG481_002550	COG1194	a g-specific adenine glycosylase
CG481_002575	COG3557	Belongs to the UPF0374 family
CG481_002580	COG1132	(ABC) transporter
CG481_002585	COG4129	membrane
CG481_002590	COG0069	glutamate synthase activity
CG481_002590	COG0067	glutamate synthase
CG481_002590	COG0070	glutamate synthase
CG481_002595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG481_002620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG481_002625	COG0735	belongs to the Fur family
CG481_002745	COG0457	Tetratricopeptide repeat
CG481_002750	COG0217	transcriptional regulatory protein
CG481_002755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG481_002760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG481_002780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CG481_002790	COG2766	serine protein kinase
CG481_002815	COG1280	lysine exporter protein (LysE YggA)
CG481_002855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG481_002865	COG1585	Membrane protein implicated in regulation of membrane protease activity
CG481_002870	COG2268	Band 7 protein
CG481_002910	COG3290	protein histidine kinase activity
CG481_002915	COG4565	transcriptional regulatory protein
CG481_002920	COG3493	citrate carrier protein
CG481_002925	COG0281	malic enzyme
CG481_002940	COG5002	protein histidine kinase activity
CG481_002945	COG0745	RESPONSE REGULATOR receiver
CG481_002955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CG481_002960	COG3383	formate dehydrogenase (NAD+) activity
CG481_002965	COG2427	Protein of unknown function (DUF1641)
CG481_002975	COG0840	transmembrane signaling receptor activity
CG481_002985	COG0531	amino acid
CG481_003000	COG0640	Transcriptional regulator
CG481_003005	COG2217	Heavy metal translocating P-type atpase
CG481_003010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG481_003020	COG3227	Zinc metalloprotease (Elastase)
CG481_003035	COG2217	Heavy metal translocating P-type atpase
CG481_003055	COG2720	vancomycin resistance protein
CG481_003060	COG1316	TRANSCRIPTIONal
CG481_003070	COG1253	flavin adenine dinucleotide binding
CG481_003075	COG1027	Aspartate ammonia-lyase
CG481_003080	COG1620	l-lactate permease
CG481_003100	COG3104	oligopeptide transport
CG481_003105	COG0156	8-amino-7-oxononanoate synthase activity
CG481_003110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG481_003115	COG4548	von Willebrand factor, type A
CG481_003120	COG0714	Associated with various cellular activities
CG481_003125	COG0531	amino acid
CG481_003130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG481_003135	COG1115	amino acid carrier protein
CG481_003145	COG1126	abc transporter atp-binding protein
CG481_003150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG481_003155	COG0765	amino acid transport
CG481_003160	COG0765	amino acid transport
CG481_003175	COG5002	protein histidine kinase activity
CG481_003190	COG0659	secondary active sulfate transmembrane transporter activity
CG481_003195	COG0589	response to stress
CG481_003205	COG0747	negative chemotaxis
CG481_003215	COG0601	transmembrane transport
CG481_003220	COG4608	Belongs to the ABC transporter superfamily
CG481_003230	COG2271	Major facilitator Superfamily
CG481_003235	COG1846	Transcriptional regulator
CG481_003240	COG0477	Major facilitator Superfamily
CG481_003245	COG1609	Transcriptional regulator
CG481_003250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG481_003255	COG1869	D-ribose catabolic process
CG481_003260	COG1129	ABC transporter
CG481_003265	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG481_003270	COG1879	ABC-type sugar transport system periplasmic component
CG481_003275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CG481_003290	COG3568	Endonuclease Exonuclease Phosphatase
CG481_003315	COG0840	transmembrane signaling receptor activity
CG481_003320	COG3583	domain protein
CG481_003320	COG3584	3D domain protein
CG481_003325	COG1476	TRANSCRIPTIONal
CG481_003355	COG1114	Component of the transport system for branched-chain amino acids
CG481_003365	COG1113	amino acid transport
CG481_003370	COG2153	protein acetylation
CG481_003380	COG0569	domain protein
CG481_003380	COG0475	glutathione-regulated potassium exporter activity
CG481_003395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG481_003400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CG481_003405	COG0833	amino acid
CG481_003410	COG4990	cell redox homeostasis
CG481_003425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG481_003430	COG0697	spore germination
CG481_003435	COG0531	amino acid
CG481_003450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG481_003455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG481_003460	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG481_003460	COG1918	ferrous iron import across plasma membrane
CG481_003465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG481_003470	COG0573	inorganic phosphate transmembrane transporter activity
CG481_003475	COG0581	inorganic phosphate transmembrane transporter activity
CG481_003480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG481_003520	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG481_003595	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CG481_003620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG481_003625	COG1116	anion transmembrane transporter activity
CG481_003630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG481_003635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG481_003640	COG0352	thiamine-phosphate diphosphorylase activity
CG481_003645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG481_003650	COG2104	thiamine diphosphate biosynthetic process
CG481_003655	COG2022	thiamine diphosphate biosynthetic process
CG481_003660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG481_003665	COG0351	phosphomethylpyrimidine kinase
CG481_003695	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CG481_003700	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CG481_003705	COG2205	protein histidine kinase activity
CG481_003710	COG2814	Major facilitator Superfamily
CG481_003715	COG1846	Transcriptional regulator
CG481_003725	COG2252	PERMEase
CG481_003730	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_003735	COG1376	ErfK ybiS ycfS ynhG family protein
CG481_003790	COG0778	Nitroreductase
CG481_003800	COG2719	SpoVR family
CG481_003810	COG1316	TRANSCRIPTIONal
CG481_003815	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG481_003830	COG0577	efflux transmembrane transporter activity
CG481_003835	COG1136	(ABC) transporter
CG481_003845	COG1114	Component of the transport system for branched-chain amino acids
CG481_003850	COG3546	catalase activity
CG481_003905	COG0475	glutathione-regulated potassium exporter activity
CG481_003910	COG1737	Transcriptional regulator
CG481_003920	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CG481_003925	COG1263	PTS System
CG481_003925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG481_003940	COG1522	sequence-specific DNA binding
CG481_003955	COG0531	amino acid
CG481_003965	COG1012	belongs to the aldehyde dehydrogenase family
CG481_003970	COG1132	(ABC) transporter
CG481_003975	COG1132	(ABC) transporter
CG481_003985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG481_003990	COG0765	amino acid transport
CG481_003995	COG1126	abc transporter atp-binding protein
CG481_004010	COG0189	ligase activity
CG481_004015	COG4399	Belongs to the UPF0754 family
CG481_004020	COG3679	Belongs to the UPF0342 family
CG481_004025	COG4585	Histidine kinase
CG481_004030	COG2197	response regulator
CG481_004085	COG0561	phosphatase activity
CG481_004095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG481_004125	COG2244	polysaccharide biosynthetic process
CG481_004135	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG481_004155	COG1696	Membrane protein involved in D-alanine export
CG481_004170	COG1024	Enoyl-CoA hydratase
CG481_004185	COG1363	Peptidase, m42
CG481_004200	COG2239	Acts as a magnesium transporter
CG481_004205	COG0772	Belongs to the SEDS family
CG481_004210	COG1115	amino acid carrier protein
CG481_004285	COG1476	TRANSCRIPTIONal
CG481_004420	COG3829	transcription factor binding
CG481_004420	COG3290	protein histidine kinase activity
CG481_004445	COG1061	Type III restriction enzyme res subunit
CG481_004485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CG481_004495	COG4638	Rieske (2fe-2S)
CG481_004500	COG1012	belongs to the aldehyde dehydrogenase family
CG481_004505	COG0473	3-isopropylmalate dehydrogenase activity
CG481_004525	COG1064	alcohol dehydrogenase
CG481_004540	COG3246	L-lysine catabolic process to acetate
CG481_004575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CG481_004585	COG4641	Protein conserved in bacteria
CG481_004600	COG3711	transcriptional antiterminator
CG481_004605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG481_004605	COG1263	PTS System
CG481_004605	COG2190	(PTS) system
CG481_004610	COG2723	6-phospho-beta-galactosidase activity
CG481_004620	COG2376	Dihydroxyacetone kinase
CG481_004625	COG0393	Putative heavy-metal-binding
CG481_004655	COG0420	3'-5' exonuclease activity
CG481_004660	COG4717	serine-type aminopeptidase activity
CG481_004665	COG3481	metal-dependent phosphohydrolase, HD sub domain
CG481_004680	COG0577	efflux transmembrane transporter activity
CG481_004685	COG1136	(ABC) transporter
CG481_004695	COG5002	protein histidine kinase activity
CG481_004700	COG0745	RESPONSE REGULATOR receiver
CG481_004710	COG1316	TRANSCRIPTIONal
CG481_004725	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CG481_004730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CG481_004735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG481_004740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CG481_004760	COG1846	Transcriptional regulator
CG481_004765	COG4980	gas vesicle protein
CG481_004775	COG0537	adenosine 5'-monophosphoramidase activity
CG481_004780	COG1131	(ABC) transporter
CG481_004785	COG4473	ABC transporter
CG481_004805	COG3402	PFAM membrane-flanked domain
CG481_004815	COG2329	Antibiotic biosynthesis monooxygenase
CG481_004820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG481_004825	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CG481_004865	COG1309	transcriptional regulator
CG481_004875	COG0438	transferase activity, transferring glycosyl groups
CG481_004875	COG1216	Glycosyl transferase, family 2
CG481_004890	COG1609	Transcriptional regulator
CG481_004900	COG1234	tRNA 3'-trailer cleavage
CG481_004905	COG0095	Lipoate-protein ligase
CG481_004915	COG0318	PFAM AMP-dependent synthetase and ligase
CG481_004930	COG2205	protein histidine kinase activity
CG481_004935	COG0745	RESPONSE REGULATOR receiver
CG481_004955	COG0501	Belongs to the peptidase M48B family
CG481_004960	COG0840	transmembrane signaling receptor activity
CG481_004965	COG0697	spore germination
CG481_004985	COG2224	Isocitrate lyase
CG481_004990	COG1278	Cold shock
CG481_005000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG481_005010	COG1396	sequence-specific DNA binding
CG481_005100	COG1598	PFAM Uncharacterised protein family UPF0150
CG481_005220	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG481_005235	COG2207	Transcriptional regulator
CG481_005235	COG3708	Transcriptional regulator
CG481_005270	COG0398	Pfam SNARE associated Golgi protein
CG481_005280	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CG481_005285	COG1074	ATP-dependent DNA helicase activity
CG481_005325	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG481_005355	COG0753	catalase activity
CG481_005365	COG1874	Beta-galactosidase
CG481_005365	COG0366	Alpha amylase catalytic
CG481_005370	COG1666	GTP binding
CG481_005375	COG2996	Protein conserved in bacteria
CG481_005390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG481_005405	COG0561	phosphatase activity
CG481_005430	COG2267	carboxylic ester hydrolase activity
CG481_005450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG481_005455	COG5504	Zn-dependent protease
CG481_005465	COG0180	Tryptophanyl-tRNA synthetase
CG481_005480	COG4166	transmembrane transport
CG481_005485	COG0601	transmembrane transport
CG481_005490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG481_005495	COG0444	Belongs to the ABC transporter superfamily
CG481_005500	COG4608	Belongs to the ABC transporter superfamily
CG481_005505	COG0534	Mate efflux family protein
CG481_005510	COG4166	transmembrane transport
CG481_005530	COG1393	Belongs to the ArsC family
CG481_005535	COG0861	Integral membrane protein TerC family
CG481_005555	COG1164	Oligoendopeptidase f
CG481_005570	COG2346	COG2346, Truncated hemoglobins
CG481_005585	COG2357	RelA SpoT domain protein
CG481_005595	COG0564	pseudouridine synthase activity
CG481_005605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG481_005610	COG0772	Belongs to the SEDS family
CG481_005655	COG1216	Glycosyl transferase, family 2
CG481_005680	COG0463	Glycosyl transferase, family 2
CG481_005680	COG0457	Tetratricopeptide repeat
CG481_005700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CG481_005715	COG1091	dTDP-4-dehydrorhamnose reductase activity
CG481_005740	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CG481_005745	COG2382	esterase
CG481_005760	COG5492	domain, Protein
CG481_005765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG481_005780	COG1620	l-lactate permease
CG481_005785	COG5634	Uncharacterized conserved protein (DUF2278)
CG481_005825	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG481_005830	COG0567	Dehydrogenase, E1 component
CG481_005840	COG0583	DNA-binding transcription factor activity
CG481_005845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG481_005865	COG0196	riboflavin kinase activity
CG481_005870	COG3162	membrane
CG481_005875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG481_005880	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG481_005895	COG0457	Tetratricopeptide repeat
CG481_005950	COG0673	inositol 2-dehydrogenase activity
CG481_005980	COG0457	Tetratricopeptide repeat
CG481_005985	COG0582	viral genome integration into host DNA
CG481_006020	COG1686	Belongs to the peptidase S11 family
CG481_006025	COG0681	Belongs to the peptidase S26 family
CG481_006060	COG1012	belongs to the aldehyde dehydrogenase family
CG481_006070	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG481_006075	COG1177	transmembrane transport
CG481_006080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG481_006085	COG0671	phosphoesterase, PA-phosphatase related
CG481_006090	COG2409	Drug exporters of the RND superfamily
CG481_006100	COG0564	pseudouridine synthase activity
CG481_006110	COG2340	Cysteine-rich secretory protein family
CG481_006115	COG0247	lactate metabolic process
CG481_006120	COG0277	FAD linked oxidase domain protein
CG481_006125	COG3835	regulator
CG481_006135	COG0745	RESPONSE REGULATOR receiver
CG481_006140	COG5002	protein histidine kinase activity
CG481_006145	COG2186	Transcriptional regulator
CG481_006150	COG0247	lactate metabolic process
CG481_006155	COG1139	Iron-sulfur cluster binding protein
CG481_006160	COG1556	Lactate utilization protein
CG481_006165	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CG481_006170	COG0584	glycerophosphoryl diester phosphodiesterase
CG481_006180	COG2267	carboxylic ester hydrolase activity
CG481_006185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG481_006195	COG2116	formate transmembrane transporter activity
CG481_006200	COG0861	Integral membrane protein TerC family
CG481_006205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG481_006215	COG2030	dehydratase
CG481_006235	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_006240	COG3243	poly(R)-hydroxyalkanoic acid synthase
CG481_006260	COG1840	ABC-type Fe3 transport system, periplasmic component
CG481_006265	COG3842	ATPase activity
CG481_006275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG481_006280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CG481_006285	COG1349	DNA-binding transcription factor activity
CG481_006290	COG0235	Class ii aldolase
CG481_006300	COG2861	carbohydrate metabolic process
CG481_006315	COG3852	Histidine kinase
CG481_006320	COG1846	Transcriptional regulator
CG481_006340	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CG481_006345	COG0720	synthase
CG481_006355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG481_006360	COG4873	Protein conserved in bacteria
CG481_006370	COG0456	acetyltransferase
CG481_006390	COG1780	Probably involved in ribonucleotide reductase function
CG481_006405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG481_006410	COG1725	Transcriptional regulator
CG481_006415	COG1131	(ABC) transporter
CG481_006425	COG1131	(ABC) transporter
CG481_006430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG481_006445	COG1522	sequence-specific DNA binding
CG481_006460	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG481_006465	COG2070	2-Nitropropane dioxygenase
CG481_006470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CG481_006480	COG1696	Membrane protein involved in D-alanine export
CG481_006485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG481_006500	COG0716	FMN binding
CG481_006525	COG1368	sulfuric ester hydrolase activity
CG481_006535	COG3173	Aminoglycoside phosphotransferase
CG481_006550	COG5609	conserved protein (DUF2294)
CG481_006555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG481_006560	COG3002	Belongs to the UPF0753 family
CG481_006570	COG0534	Mate efflux family protein
CG481_006585	COG1846	Transcriptional regulator
CG481_006595	COG1301	dicarboxylic acid transport
CG481_006600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG481_006610	COG3874	Sporulation protein YtfJ
CG481_006630	COG0028	Belongs to the TPP enzyme family
CG481_006635	COG0440	acetolactate synthase activity
CG481_006640	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CG481_006645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG481_006655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG481_006660	COG0066	3-isopropylmalate dehydratase activity
CG481_006670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CG481_006680	COG0131	Imidazoleglycerol-phosphate dehydratase
CG481_006685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG481_006690	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CG481_006695	COG0107	imidazoleglycerol-phosphate synthase activity
CG481_006700	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG481_006705	COG0140	phosphoribosyl-ATP diphosphatase activity
CG481_006720	COG1183	phosphatidylcholine synthase activity
CG481_006725	COG1368	sulfuric ester hydrolase activity
CG481_006745	COG0175	sulfate reduction
CG481_006750	COG2046	Belongs to the sulfate adenylyltransferase family
CG481_006755	COG0529	Catalyzes the synthesis of activated sulfate
CG481_006760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG481_006780	COG1648	precorrin-2 dehydrogenase activity
CG481_006780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG481_006785	COG0733	neurotransmitter:sodium symporter activity
CG481_006800	COG3557	Belongs to the UPF0374 family
CG481_006805	COG1757	Na H antiporter
CG481_006820	COG4758	membrane
CG481_006825	COG4585	Histidine kinase
CG481_006830	COG2197	response regulator
CG481_006835	COG1114	Component of the transport system for branched-chain amino acids
CG481_006840	COG4085	toxin activity
CG481_006840	COG1525	nuclease
CG481_006840	COG0737	Belongs to the 5'-nucleotidase family
CG481_006870	COG3711	transcriptional antiterminator
CG481_006870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG481_006875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG481_006875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG481_006875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG481_006880	COG1482	cell wall glycoprotein biosynthetic process
CG481_006890	COG2801	Transposase and inactivated derivatives
CG481_006910	COG0730	response to heat
CG481_006915	COG0306	phosphate transporter
CG481_006920	COG1392	Phosphate transport regulator
CG481_006925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG481_006935	COG3852	Histidine kinase
CG481_006940	COG1801	Protein of unknown function DUF72
CG481_006950	COG0582	viral genome integration into host DNA
CG481_006955	COG5002	protein histidine kinase activity
CG481_006960	COG0813	purine-nucleoside phosphorylase activity
CG481_006970	COG0392	lysyltransferase activity
CG481_006970	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CG481_006985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG481_006990	COG1686	Belongs to the peptidase S11 family
CG481_006995	COG2715	membrane protein required for spore maturation
CG481_007000	COG0700	Nucleoside recognition
CG481_007005	COG1187	pseudouridine synthase activity
CG481_007015	COG1333	cytochrome c biogenesis protein
CG481_007020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG481_007025	COG0745	RESPONSE REGULATOR receiver
CG481_007030	COG5002	protein histidine kinase activity
CG481_007035	COG2096	Adenosyltransferase
CG481_007050	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CG481_007055	COG1141	Ferredoxin
CG481_007065	COG0514	ATP-dependent DNA helicase (RecQ)
CG481_007070	COG1266	CAAX protease self-immunity
CG481_007080	COG1408	metallophosphoesterase
CG481_007095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG481_007110	COG0492	ferredoxin-NADP+ reductase activity
CG481_007125	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG481_007135	COG1304	FMN binding
CG481_007160	COG1160	GTP binding
CG481_007165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG481_007185	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG481_007195	COG0302	gtp cyclohydrolase
CG481_007200	COG0142	geranyltranstransferase activity
CG481_007205	COG2226	methyltransferase
CG481_007210	COG0142	geranyltranstransferase activity
CG481_007215	COG0105	UTP biosynthetic process
CG481_007220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG481_007225	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CG481_007230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG481_007235	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG481_007240	COG0457	Tetratricopeptide repeat
CG481_007245	COG5582	Belongs to the UPF0302 family
CG481_007260	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG481_007270	COG4347	Protein of unknown function (DUF1405)
CG481_007285	COG2738	Putative neutral zinc metallopeptidase
CG481_007295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG481_007300	COG1694	Mazg nucleotide pyrophosphohydrolase
CG481_007305	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CG481_007310	COG1803	Methylglyoxal synthase
CG481_007315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG481_007320	COG0438	transferase activity, transferring glycosyl groups
CG481_007325	COG0617	tRNA 3'-terminal CCA addition
CG481_007340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CG481_007345	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG481_007350	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CG481_007355	COG1199	ATP-dependent helicase activity
CG481_007355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG481_007375	COG3935	DnaD domain protein
CG481_007380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG481_007390	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG481_007390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG481_007395	COG3331	DNA recombination
CG481_007430	COG4474	Belongs to the UPF0398 family
CG481_007435	COG3599	regulation of cell shape
CG481_007445	COG0116	Belongs to the methyltransferase superfamily
CG481_007455	COG1199	ATP-dependent helicase activity
CG481_007460	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CG481_007465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG481_007470	COG2233	PERMEase
CG481_007475	COG2311	Membrane
CG481_007480	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG481_007490	COG0456	acetyltransferase
CG481_007530	COG3766	membrane
CG481_007535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG481_007540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG481_007545	COG1733	regulation of RNA biosynthetic process
CG481_007565	COG0328	RNA-DNA hybrid ribonuclease activity
CG481_007595	COG1278	Cold shock
CG481_007605	COG3162	membrane
CG481_007610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG481_007615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG481_007620	COG0475	glutathione-regulated potassium exporter activity
CG481_007625	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG481_007630	COG2323	membrane
CG481_007635	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CG481_007660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG481_007670	COG2201	protein-glutamate methylesterase activity
CG481_007675	COG2198	Histidine kinase
CG481_007675	COG0643	Histidine kinase
CG481_007680	COG1776	CheC inhibitor of MCP methylation
CG481_007680	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG481_007695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CG481_007715	COG1256	bacterial-type flagellum assembly
CG481_007720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG481_007740	COG1815	bacterial-type flagellum-dependent cell motility
CG481_007745	COG1558	bacterial-type flagellum-dependent cell motility
CG481_007750	COG1677	Flagellar hook-basal body complex protein FliE
CG481_007760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG481_007770	COG1157	protein secretion by the type III secretion system
CG481_007805	COG0835	chemotaxis
CG481_007805	COG0784	Response regulator, receiver
CG481_007815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG481_007820	COG0463	Glycosyl transferase, family 2
CG481_007820	COG0457	Tetratricopeptide repeat
CG481_007835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG481_007840	COG0741	lytic transglycosylase activity
CG481_007850	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG481_007855	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG481_007855	COG1776	CheC inhibitor of MCP methylation
CG481_007865	COG1338	Plays a role in the flagellum-specific transport system
CG481_007870	COG1987	bacterial-type flagellum assembly
CG481_007880	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG481_007885	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG481_007890	COG1419	protein localization to endoplasmic reticulum
CG481_007895	COG4786	Flagellar basal body rod
CG481_007900	COG1136	(ABC) transporter
CG481_007900	COG0577	efflux transmembrane transporter activity
CG481_007930	COG1309	transcriptional regulator
CG481_007950	COG2814	Major facilitator Superfamily
CG481_007960	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_007995	COG0367	asparagine synthase
CG481_008015	COG1802	Transcriptional regulator
CG481_008030	COG1757	Na H antiporter
CG481_008035	COG0114	fumarate hydratase activity
CG481_008060	COG0534	Mate efflux family protein
CG481_008065	COG3340	Belongs to the peptidase S51 family
CG481_008070	COG2733	membrane
CG481_008080	COG1280	lysine exporter protein (LysE YggA)
CG481_008085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG481_008100	COG2502	aspartate--ammonia ligase
CG481_008105	COG1309	transcriptional regulator
CG481_008110	COG0109	protoheme IX farnesyltransferase activity
CG481_008140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG481_008150	COG4166	transmembrane transport
CG481_008155	COG2223	nitrite transmembrane transporter activity
CG481_008160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG481_008165	COG2244	polysaccharide biosynthetic process
CG481_008170	COG0733	neurotransmitter:sodium symporter activity
CG481_008175	COG5566	PFAM Mor transcription activator
CG481_008185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG481_008190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG481_008200	COG0129	dihydroxy-acid dehydratase activity
CG481_008205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG481_008210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG481_008215	COG2814	Major facilitator Superfamily
CG481_008220	COG3384	dioxygenase
CG481_008240	COG0402	S-adenosylhomocysteine deaminase activity
CG481_008245	COG4166	transmembrane transport
CG481_008255	COG1914	H( )-stimulated, divalent metal cation uptake system
CG481_008270	COG0083	homoserine kinase activity
CG481_008280	COG2390	Transcriptional regulator
CG481_008285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CG481_008310	COG1510	regulation of RNA biosynthetic process
CG481_008320	COG1454	alcohol dehydrogenase
CG481_008335	COG1012	belongs to the aldehyde dehydrogenase family
CG481_008350	COG0628	permease
CG481_008355	COG0039	L-malate dehydrogenase activity
CG481_008360	COG0523	cobalamin synthesis protein
CG481_008385	COG1686	Belongs to the peptidase S11 family
CG481_008400	COG1388	LysM domain
CG481_008400	COG0791	NLP P60 protein
CG481_008405	COG0300	oxidoreductase activity
CG481_008415	COG0460	homoserine dehydrogenase
CG481_008425	COG0083	homoserine kinase activity
CG481_008430	COG1316	TRANSCRIPTIONal
CG481_008435	COG0726	polysaccharide deacetylase
CG481_008445	COG1285	pathogenesis
CG481_008450	COG1247	-acetyltransferase
CG481_008485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CG481_008490	COG0577	efflux transmembrane transporter activity
CG481_008495	COG2409	Drug exporters of the RND superfamily
CG481_008500	COG1404	Belongs to the peptidase S8 family
CG481_008515	COG0840	transmembrane signaling receptor activity
CG481_008535	COG0783	Belongs to the Dps family
CG481_008555	COG0523	cobalamin synthesis protein
CG481_008565	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG481_008580	COG1902	pentaerythritol trinitrate reductase activity
CG481_008585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG481_008595	COG4166	transmembrane transport
CG481_008600	COG0346	lactoylglutathione lyase activity
CG481_008615	COG1051	belongs to the nudix hydrolase family
CG481_008620	COG0586	Pfam SNARE associated Golgi protein
CG481_008625	COG2244	polysaccharide biosynthetic process
CG481_008635	COG0701	Predicted permease
CG481_008640	COG3689	TIGRFAM TIGR03943 family protein
CG481_008645	COG1607	acyl-coa hydrolase
CG481_008655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG481_008665	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_008675	COG2839	Protein conserved in bacteria
CG481_008680	COG1253	flavin adenine dinucleotide binding
CG481_008695	COG1114	Component of the transport system for branched-chain amino acids
CG481_008720	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG481_008730	COG1876	peptidase activity
CG481_008780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG481_008785	COG1819	glycosyl
CG481_008790	COG1819	glycosyl
CG481_008795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG481_008840	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG481_008880	COG3874	Sporulation protein YtfJ
CG481_008905	COG2226	methyltransferase
CG481_008930	COG0386	Belongs to the glutathione peroxidase family
CG481_008960	COG0640	Transcriptional regulator
CG481_008965	COG0798	PFAM Bile acid sodium symporter
CG481_008970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG481_009015	COG1418	mRNA catabolic process
CG481_009020	COG0488	(ABC) transporter
CG481_009030	COG0629	single-stranded DNA binding
CG481_009035	COG1413	lyase activity
CG481_009050	COG2136	Putative SAM-dependent methyltransferase
CG481_009050	COG2521	methyltransferase
CG481_009055	COG0018	arginyl-trna synthetase
CG481_009065	COG0733	neurotransmitter:sodium symporter activity
CG481_009085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG481_009090	COG0477	Major facilitator Superfamily
CG481_009105	COG1454	alcohol dehydrogenase
CG481_009110	COG2610	gluconate transmembrane transporter activity
CG481_009120	COG0456	acetyltransferase
CG481_009125	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG481_009135	COG1131	(ABC) transporter
CG481_009140	COG4473	ABC transporter
CG481_009155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG481_009160	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG481_009170	COG0768	penicillin binding
CG481_009180	COG0204	Acyl-transferase
CG481_009190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG481_009195	COG0805	protein transport
CG481_009205	COG1307	EDD domain protein, DegV family
CG481_009215	COG1999	signal sequence binding
CG481_009220	COG0071	Belongs to the small heat shock protein (HSP20) family
CG481_009225	COG0367	asparagine synthase
CG481_009240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG481_009260	COG0071	Belongs to the small heat shock protein (HSP20) family
CG481_009270	COG1737	Transcriptional regulator
CG481_009275	COG1070	Carbohydrate kinase
CG481_009285	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CG481_009340	COG1151	hydroxylamine reductase activity
CG481_009350	COG1253	flavin adenine dinucleotide binding
CG481_009355	COG5506	Protein of unknown function (DUF1694)
CG481_009375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG481_009380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CG481_009385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG481_009400	COG3829	transcription factor binding
CG481_009410	COG1509	lysine 2,3-aminomutase activity
CG481_009420	COG4479	Belongs to the UPF0346 family
CG481_009425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG481_009455	COG0515	serine threonine protein kinase
CG481_009455	COG1357	PFAM Pentapeptide repeats (8 copies)
CG481_009460	COG0671	phosphoesterase, PA-phosphatase related
CG481_009465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG481_009470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG481_009515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CG481_009525	COG0726	polysaccharide deacetylase
CG481_009530	COG1408	metallophosphoesterase
CG481_009535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG481_009540	COG2323	membrane
CG481_009545	COG0671	phosphoesterase, PA-phosphatase related
CG481_009555	COG1280	lysine exporter protein (LysE YggA)
CG481_009560	COG3403	YqcI/YcgG family
CG481_009590	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG481_009590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG481_009600	COG0372	Belongs to the citrate synthase family
CG481_009605	COG2079	MmgE PrpD family protein
CG481_009610	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CG481_009615	COG1960	acyl-CoA dehydrogenase activity
CG481_009620	COG2084	Dehydrogenase
CG481_009625	COG1012	belongs to the aldehyde dehydrogenase family
CG481_009635	COG1280	lysine exporter protein (LysE YggA)
CG481_009655	COG0420	3'-5' exonuclease activity
CG481_009660	COG0419	ATPase involved in DNA repair
CG481_009665	COG3104	oligopeptide transport
CG481_009690	COG1131	(ABC) transporter
CG481_009715	COG1131	(ABC) transporter
CG481_009720	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG481_009740	COG1942	4-Oxalocrotonate Tautomerase
CG481_009755	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_009760	COG1169	isochorismate synthase
CG481_009765	COG1021	2,3-dihydroxybenzoate-AMP ligase
CG481_009770	COG3433	isochorismatase activity
CG481_009770	COG1535	isochorismatase
CG481_009775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG481_009780	COG3251	PFAM MbtH domain protein
CG481_009785	COG2814	Major facilitator Superfamily
CG481_009850	COG0776	regulation of translation
CG481_009865	COG2329	Antibiotic biosynthesis monooxygenase
CG481_009915	COG0667	Aldo Keto reductase
CG481_009935	COG0010	Belongs to the arginase family
CG481_009945	COG1132	(ABC) transporter
CG481_009950	COG1132	(ABC) transporter
CG481_009980	COG1649	PFAM Uncharacterised BCR, COG1649
CG481_009995	COG2971	BadF BadG BcrA BcrD
CG481_010015	COG0588	phosphoglycerate mutase activity
CG481_010045	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG481_010055	COG1960	acyl-CoA dehydrogenase activity
CG481_010060	COG0439	Biotin carboxylase
CG481_010065	COG0511	ligase activity, forming carbon-carbon bonds
CG481_010070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG481_010075	COG1024	Enoyl-CoA hydratase
CG481_010080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG481_010085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG481_010095	COG1216	Glycosyl transferase, family 2
CG481_010100	COG0640	Transcriptional regulator
CG481_010115	COG1686	Belongs to the peptidase S11 family
CG481_010120	COG5002	protein histidine kinase activity
CG481_010150	COG0789	Transcriptional regulator
CG481_010175	COG0745	RESPONSE REGULATOR receiver
CG481_010195	COG2002	toxin-antitoxin pair type II binding
CG481_010200	COG3409	Peptidoglycan-binding domain 1 protein
CG481_010200	COG3773	Cell wall hydrolase
CG481_010220	COG0201	protein transport
CG481_010240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG481_010245	COG0322	excinuclease ABC activity
CG481_010260	COG4667	esterase of the alpha-beta hydrolase superfamily
CG481_010300	COG2223	nitrite transmembrane transporter activity
CG481_010350	COG1216	Glycosyl transferase, family 2
CG481_010365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG481_010370	COG1279	arginine transmembrane transporter activity
CG481_010410	COG1794	racemase activity, acting on amino acids and derivatives
CG481_010420	COG2828	Protein conserved in bacteria
CG481_010425	COG5002	protein histidine kinase activity
CG481_010430	COG0561	phosphatase activity
CG481_010450	COG2124	cytochrome p450
CG481_010495	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG481_010525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG481_010530	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG481_010540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG481_010550	COG2959	enzyme of heme biosynthesis
CG481_010555	COG3409	Peptidoglycan-binding domain 1 protein
CG481_010555	COG3773	Cell wall hydrolase
CG481_010580	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CG481_010585	COG3844	kynureninase activity
CG481_010595	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_010605	COG4176	ABC-type proline glycine betaine transport system permease component
CG481_010610	COG4175	Glycine betaine
CG481_010610	COG0517	IMP dehydrogenase activity
CG481_010640	COG2153	protein acetylation
CG481_010665	COG0514	ATP-dependent DNA helicase (RecQ)
CG481_010685	COG4637	Psort location Cytoplasmic, score
CG481_010690	COG1227	inorganic diphosphatase activity
CG481_010700	COG3397	chitin binding
CG481_010740	COG4166	transmembrane transport
CG481_010750	COG4948	Mandelate Racemase Muconate Lactonizing
CG481_010820	COG1307	EDD domain protein, DegV family
CG481_010890	COG2261	transglycosylase associated protein
CG481_010910	COG2826	transposase and inactivated derivatives, IS30 family
CG481_010940	COG3973	AAA domain
CG481_010950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG481_010975	COG0628	permease
CG481_010990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG481_010995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG481_011000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG481_011015	COG2746	aminoglycoside 3-N-acetyltransferase activity
CG481_011035	COG0456	acetyltransferase
CG481_011035	COG0454	-acetyltransferase
CG481_011045	COG0726	polysaccharide deacetylase
CG481_011050	COG3037	sugar-specific permease SgaT UlaA
CG481_011060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG481_011065	COG1368	sulfuric ester hydrolase activity
CG481_011070	COG0488	(ABC) transporter
CG481_011095	COG0346	lactoylglutathione lyase activity
CG481_011105	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG481_011110	COG1518	maintenance of DNA repeat elements
CG481_011150	COG2329	Antibiotic biosynthesis monooxygenase
CG481_011165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG481_011190	COG0494	nUDIX hydrolase
CG481_011205	COG0456	acetyltransferase
CG481_011210	COG0477	Major facilitator Superfamily
CG481_011225	COG0697	spore germination
CG481_011230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG481_011240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG481_011255	COG0730	response to heat
CG481_011265	COG0833	amino acid
CG481_011285	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CG481_011300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CG481_011305	COG1984	allophanate hydrolase subunit 2
CG481_011310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG481_011315	COG1414	Transcriptional regulator
CG481_011330	COG1960	acyl-CoA dehydrogenase activity
CG481_011360	COG0346	lactoylglutathione lyase activity
CG481_011370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG481_011375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG481_011380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG481_011385	COG0438	transferase activity, transferring glycosyl groups
CG481_011400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG481_011405	COG0438	transferase activity, transferring glycosyl groups
CG481_011410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG481_011420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG481_011440	COG4851	CamS sex pheromone cAM373 precursor
CG481_011540	COG0477	Major facilitator Superfamily
CG481_011555	COG1846	Transcriptional regulator
CG481_011560	COG2814	Major facilitator Superfamily
CG481_011570	COG2031	fatty acid transporter
CG481_011600	COG1122	ATPase activity
CG481_011605	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG481_011625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG481_011640	COG1131	(ABC) transporter
CG481_011700	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CG481_011705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG481_011710	COG0579	oxidoreductase
CG481_011715	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CG481_011725	COG1253	flavin adenine dinucleotide binding
CG481_011730	COG0789	Transcriptional regulator
CG481_011735	COG3813	Protein conserved in bacteria
CG481_011750	COG0384	phenazine biosynthesis protein PhzF
CG481_011815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG481_011860	COG0577	efflux transmembrane transporter activity
CG481_011860	COG1136	(ABC) transporter
CG481_011930	COG0577	efflux transmembrane transporter activity
CG481_011930	COG1136	(ABC) transporter
CG481_011985	COG2072	flavoprotein involved in K transport
CG481_012010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG481_012015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG481_012030	COG1193	negative regulation of DNA recombination
CG481_012040	COG1164	Oligoendopeptidase f
CG481_012060	COG0584	glycerophosphoryl diester phosphodiesterase
CG481_012065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG481_012095	COG3397	chitin binding
CG481_012105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG481_012110	COG0277	FAD linked oxidase domain protein
CG481_012115	COG1285	pathogenesis
CG481_012120	COG2720	vancomycin resistance protein
CG481_012155	COG4824	toxin secretion phage lysis holin
CG481_012265	COG0270	DNA (cytosine-5-)-methyltransferase activity
CG481_012310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CG481_012330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG481_012330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG481_012400	COG1484	DNA-dependent DNA replication
CG481_012440	COG0582	viral genome integration into host DNA
CG481_012465	COG1278	Cold shock
CG481_012475	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_012480	COG0165	Argininosuccinate lyase
CG481_012495	COG3409	Peptidoglycan-binding domain 1 protein
CG481_012510	COG4145	pantothenate transmembrane transporter activity
CG481_012520	COG1012	belongs to the aldehyde dehydrogenase family
CG481_012535	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CG481_012540	COG2962	Rard protein
CG481_012575	COG2226	methyltransferase
CG481_012580	COG4166	transmembrane transport
CG481_012585	COG4166	transmembrane transport
CG481_012595	COG0673	inositol 2-dehydrogenase activity
CG481_012600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG481_012605	COG0187	DNA topoisomerase II activity
CG481_012615	COG1832	CoA-binding protein
CG481_012620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG481_012625	COG0745	RESPONSE REGULATOR receiver
CG481_012640	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG481_012645	COG4841	protein insertion into membrane
CG481_012650	COG0824	Thioesterase
CG481_012680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG481_012685	COG3655	Transcriptional regulator
CG481_012705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG481_012715	COG0726	polysaccharide deacetylase
CG481_012745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG481_012750	COG0318	PFAM AMP-dependent synthetase and ligase
CG481_012780	COG0457	Tetratricopeptide repeat
CG481_012860	COG2826	transposase and inactivated derivatives, IS30 family
CG481_012875	COG0534	Mate efflux family protein
CG481_012905	COG3023	N-Acetylmuramoyl-L-alanine amidase
CG481_012915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG481_012925	COG5002	protein histidine kinase activity
CG481_012935	COG0010	Belongs to the arginase family
CG481_012940	COG1228	amidohydrolase
CG481_012945	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CG481_012950	COG2986	histidine ammonia-lyase
CG481_012975	COG4846	Membrane protein involved in cytochrome C biogenesis
CG481_012980	COG0785	Cytochrome C biogenesis protein
CG481_012995	COG0583	DNA-binding transcription factor activity
CG481_013000	COG1380	Effector of murein hydrolase LrgA
CG481_013005	COG1346	cytolysis
CG481_013010	COG4187	Peptidase family M20/M25/M40
CG481_013020	COG0833	amino acid
CG481_013030	COG0730	response to heat
CG481_013040	COG3409	Peptidoglycan-binding domain 1 protein
CG481_013040	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG481_013055	COG1132	(ABC) transporter
CG481_013060	COG1132	(ABC) transporter
CG481_013065	COG3763	UPF0154 protein
CG481_013080	COG3639	organic phosphonate transmembrane transporter activity
CG481_013085	COG3639	organic phosphonate transmembrane transporter activity
CG481_013100	COG0737	Belongs to the 5'-nucleotidase family
CG481_013105	COG4224	UPF0291 protein
CG481_013110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG481_013115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CG481_013130	COG1695	Transcriptional regulator
CG481_013170	COG3328	transposase activity
CG481_013175	COG3328	transposase activity
CG481_013185	COG1598	PFAM Uncharacterised protein family UPF0150
CG481_013195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG481_013220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG481_013240	COG0730	response to heat
CG481_013310	COG0174	glutamine synthetase
CG481_013315	COG0789	Transcriptional regulator
CG481_013320	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CG481_013325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG481_013330	COG2860	membrane
CG481_013335	COG0464	growth
CG481_013350	COG1923	regulation of RNA biosynthetic process
CG481_013355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG481_013365	COG3584	3D domain protein
CG481_013365	COG1388	LysM domain
CG481_013370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG481_013370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG481_013370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG481_013375	COG1105	Belongs to the carbohydrate kinase PfkB family
CG481_013380	COG1349	DNA-binding transcription factor activity
CG481_013385	COG2322	membrane
CG481_013410	COG2116	formate transmembrane transporter activity
CG481_013420	COG1937	Protein conserved in bacteria
CG481_013425	COG2819	hydrolase of the alpha beta superfamily
CG481_013430	COG1120	ATPase activity
CG481_013435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG481_013440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG481_013445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG481_013450	COG2706	6-phosphogluconolactonase activity
CG481_013465	COG0346	lactoylglutathione lyase activity
CG481_013480	COG1113	amino acid transport
CG481_013505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG481_013510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG481_013520	COG4550	Control of competence regulator ComK, YlbF/YmcA
CG481_013525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG481_013530	COG1013	pyruvate-flavodoxin oxidoreductase activity
CG481_013535	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CG481_013535	COG0674	pyruvate-flavodoxin oxidoreductase activity
CG481_013545	COG2359	stage V sporulation protein S
CG481_013550	COG1692	metallophosphoesterase
CG481_013555	COG1418	mRNA catabolic process
CG481_013560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG481_013565	COG1546	Belongs to the CinA family
CG481_013565	COG1058	Belongs to the CinA family
CG481_013570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG481_013575	COG1426	Protein conserved in bacteria
CG481_013595	COG0300	oxidoreductase activity
CG481_013600	COG0612	Peptidase, M16
CG481_013605	COG0612	Peptidase, M16
CG481_013630	COG2188	Transcriptional regulator
CG481_013635	COG1674	ftsk spoiiie
CG481_013650	COG0740	serine-type endopeptidase activity
CG481_013675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG481_013695	COG0527	aspartate kinase activity
CG481_013700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG481_013705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG481_013710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG481_013715	COG1873	PFAM PRC-barrel domain
CG481_013720	COG0612	Peptidase, M16
CG481_013725	COG0726	polysaccharide deacetylase
CG481_013730	COG1185	polyribonucleotide nucleotidyltransferase activity
CG481_013740	COG0196	riboflavin kinase activity
CG481_013745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG481_013750	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CG481_013755	COG1550	Protein conserved in bacteria
CG481_013760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CG481_013765	COG1358	cellular component organization or biogenesis
CG481_013770	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CG481_013775	COG0195	Participates in both transcription termination and antitermination
CG481_013780	COG0779	Required for maturation of 30S ribosomal subunits
CG481_013790	COG0442	prolyl-tRNA aminoacylation
CG481_013795	COG0750	zinc metalloprotease
CG481_013805	COG4589	Belongs to the CDS family
CG481_013815	COG0233	cytoplasmic translational termination
CG481_013820	COG0528	UMP kinase activity
CG481_013825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG481_013830	COG0052	Belongs to the universal ribosomal protein uS2 family
CG481_013835	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CG481_013840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CG481_013845	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CG481_013850	COG4974	Belongs to the 'phage' integrase family
CG481_013855	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CG481_013860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG481_013865	COG0758	DNA mediated transformation
CG481_013870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CG481_013875	COG0045	succinate-CoA ligase (ADP-forming) activity
CG481_013880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG481_013895	COG0335	large ribosomal subunit rRNA binding
CG481_013905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CG481_013910	COG1837	Belongs to the UPF0109 family
CG481_013915	COG0228	four-way junction DNA binding
CG481_013920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG481_013925	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CG481_013930	COG0552	protein localization to endoplasmic reticulum
CG481_013935	COG1196	nuclear chromosome segregation
CG481_013940	COG0571	ribonuclease III activity
CG481_013950	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_013955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CG481_013960	COG0416	fatty acid biosynthetic process
CG481_013965	COG2050	protein possibly involved in aromatic compounds catabolism
CG481_013965	COG1349	DNA-binding transcription factor activity
CG481_013970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG481_013975	COG1461	Dihydroxyacetone kinase
CG481_013980	COG1302	Protein conserved in bacteria
CG481_013985	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CG481_013995	COG1564	THIamine pyrophosphokinase
CG481_014000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CG481_014005	COG1162	GTPase activity
CG481_014010	COG0515	serine threonine protein kinase
CG481_014010	COG2815	serine threonine protein kinase
CG481_014015	COG0631	protein serine/threonine phosphatase activity
CG481_014020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG481_014025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG481_014025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG481_014030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG481_014035	COG0242	peptide deformylase activity
CG481_014040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG481_014050	COG1758	RNA polymerase activity
CG481_014055	COG0194	GDP metabolic process
CG481_014065	COG1561	YicC-like family, N-terminal region
CG481_014070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG481_014095	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CG481_014100	COG0284	orotidine-5'-phosphate decarboxylase activity
CG481_014105	COG0167	dihydroorotate dehydrogenase activity
CG481_014110	COG0543	2 iron, 2 sulfur cluster binding
CG481_014115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CG481_014125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CG481_014130	COG0540	Belongs to the ATCase OTCase family
CG481_014140	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CG481_014150	COG0564	pseudouridine synthase activity
CG481_014155	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG481_014165	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CG481_014170	COG3599	regulation of cell shape
CG481_014175	COG2302	S4 RNA-binding domain
CG481_014180	COG0762	integral membrane protein
CG481_014185	COG1799	cell septum assembly
CG481_014190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CG481_014200	COG1873	PFAM PRC-barrel domain
CG481_014205	COG1191	sigma factor activity
CG481_014210	COG1191	sigma factor activity
CG481_014220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG481_014225	COG0849	cell division
CG481_014230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG481_014240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG481_014245	COG0772	Belongs to the SEDS family
CG481_014250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG481_014255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG481_014260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG481_014265	COG0768	penicillin binding
CG481_014275	COG4839	cell division protein FtsL
CG481_014280	COG0275	rRNA processing
CG481_014290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CG481_014310	COG1399	metal-binding, possibly nucleic acid-binding protein
CG481_014420	COG4626	Terminase
CG481_014420	COG1802	Transcriptional regulator
CG481_014505	COG0756	dUTP diphosphatase activity
CG481_014535	COG3723	Recombinational DNA repair protein, rece pathway
CG481_014545	COG5377	YqaJ viral recombinase family
CG481_014590	COG0582	viral genome integration into host DNA
CG481_014595	COG1323	Belongs to the UPF0348 family
CG481_014600	COG3480	Lon protease (S16) C-terminal proteolytic domain
CG481_014605	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG481_014610	COG3314	Sporulation integral membrane protein YlbJ
CG481_014615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG481_014620	COG0742	ribosomal rna small subunit methyltransferase
CG481_014630	COG4471	UPF0298 protein
CG481_014635	COG3679	Belongs to the UPF0342 family
CG481_014640	COG0406	alpha-ribazole phosphatase activity
CG481_014655	COG2340	Cysteine-rich secretory protein family
CG481_014665	COG3336	cytochrome c oxidase
CG481_014690	COG0109	protoheme IX farnesyltransferase activity
CG481_014695	COG1612	heme a metabolic process
CG481_014710	COG0772	Belongs to the SEDS family
CG481_014715	COG4838	Belongs to the UPF0358 family
CG481_014720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CG481_014725	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CG481_014735	COG4896	Protein conserved in bacteria
CG481_014760	COG0483	inositol monophosphate 1-phosphatase activity
CG481_014770	COG4493	Belongs to the UPF0637 family
CG481_014775	COG4476	Belongs to the UPF0223 family
CG481_014780	COG1982	Orn Lys Arg decarboxylase major
CG481_014820	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG481_014830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG481_014845	COG0561	phosphatase activity
CG481_014860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG481_014865	COG0569	domain protein
CG481_014875	COG1473	amidohydrolase
CG481_014880	COG2171	N-acyltransferase activity
CG481_014885	COG0583	DNA-binding transcription factor activity
CG481_014890	COG0517	IMP dehydrogenase activity
CG481_014900	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CG481_014915	COG4703	Protein of unknown function (DUF1797)
CG481_014930	COG2200	EAL domain
CG481_014935	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_014940	COG1408	metallophosphoesterase
CG481_014950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CG481_014970	COG0726	polysaccharide deacetylase
CG481_014990	COG2814	Major facilitator Superfamily
CG481_014995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG481_015005	COG3209	COG3209 Rhs family protein
CG481_015015	COG2205	protein histidine kinase activity
CG481_015025	COG0436	Aminotransferase
CG481_015030	COG1609	Transcriptional regulator
CG481_015065	COG0183	Belongs to the thiolase family
CG481_015095	COG1695	Transcriptional regulator
CG481_015100	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_015110	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CG481_015115	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CG481_015120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG481_015125	COG0436	Aminotransferase
CG481_015130	COG1850	ribulose-bisphosphate carboxylase activity
CG481_015135	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CG481_015140	COG0235	Class ii aldolase
CG481_015145	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CG481_015160	COG2084	Dehydrogenase
CG481_015175	COG0778	Nitroreductase
CG481_015200	COG2190	(PTS) system
CG481_015200	COG1263	PTS System
CG481_015200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG481_015205	COG3711	transcriptional antiterminator
CG481_015220	COG0363	glucosamine-6-phosphate deaminase activity
CG481_015235	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG481_015240	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG481_015250	COG1547	Domain of unknown function (DUF309)
CG481_015260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CG481_015265	COG4086	secreted protein
CG481_015270	COG0561	phosphatase activity
CG481_015275	COG0697	spore germination
CG481_015290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG481_015315	COG0733	neurotransmitter:sodium symporter activity
CG481_015325	COG2172	sigma factor antagonist activity
CG481_015335	COG1686	Belongs to the peptidase S11 family
CG481_015345	COG1725	Transcriptional regulator
CG481_015350	COG1131	(ABC) transporter
CG481_015370	COG1846	Transcriptional regulator
CG481_015385	COG0598	Magnesium transport protein CorA
CG481_015410	COG4974	Belongs to the 'phage' integrase family
CG481_015420	COG0735	belongs to the Fur family
CG481_015425	COG1300	Membrane
CG481_015445	COG0667	Aldo Keto reductase
CG481_015450	COG0656	L-ascorbic acid biosynthetic process
CG481_015455	COG0456	acetyltransferase
CG481_015455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CG481_015465	COG1525	nuclease
CG481_015465	COG0737	Belongs to the 5'-nucleotidase family
CG481_015465	COG4085	toxin activity
CG481_015475	COG0596	Alpha beta hydrolase
CG481_015480	COG2056	Na+-H+ antiporter family
CG481_015485	COG1609	Transcriptional regulator
CG481_015490	COG0456	acetyltransferase
CG481_015495	COG1073	alpha beta
CG481_015510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG481_015510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG481_015515	COG0307	riboflavin synthase, alpha
CG481_015520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG481_015520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG481_015535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG481_015540	COG4106	trans-aconitate 2-methyltransferase activity
CG481_015545	COG0596	Alpha beta hydrolase
CG481_015550	COG0156	8-amino-7-oxononanoate synthase activity
CG481_015560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG481_015575	COG0737	Belongs to the 5'-nucleotidase family
CG481_015600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG481_015610	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG481_015620	COG0300	oxidoreductase activity
CG481_015625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG481_015630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG481_015635	COG1760	l-serine dehydratase
CG481_015640	COG1760	l-serine dehydratase
CG481_015650	COG1234	tRNA 3'-trailer cleavage
CG481_015670	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG481_015675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG481_015690	COG1376	ErfK ybiS ycfS ynhG family protein
CG481_015695	COG4129	membrane
CG481_015700	COG1126	abc transporter atp-binding protein
CG481_015705	COG0765	amino acid transport
CG481_015710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG481_015725	COG2816	NAD+ diphosphatase activity
CG481_015730	COG0772	Belongs to the SEDS family
CG481_015740	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG481_015745	COG0022	dehydrogenase e1 component
CG481_015750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG481_015755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG481_015760	COG3426	butyrate kinase activity
CG481_015765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG481_015770	COG0280	phosphate acetyltransferase
CG481_015780	COG3829	transcription factor binding
CG481_015780	COG3290	protein histidine kinase activity
CG481_015790	COG0584	glycerophosphoryl diester phosphodiesterase
CG481_015795	COG3093	addiction module antidote protein HigA
CG481_015800	COG0745	RESPONSE REGULATOR receiver
CG481_015810	COG0750	zinc metalloprotease
CG481_015815	COG0497	DNA recombination
CG481_015825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CG481_015830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG481_015840	COG1722	exodeoxyribonuclease VII activity
CG481_015845	COG1570	exodeoxyribonuclease VII activity
CG481_015850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG481_015855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG481_015860	COG1302	Protein conserved in bacteria
CG481_015865	COG0439	Biotin carboxylase
CG481_015870	COG0511	ligase activity, forming carbon-carbon bonds
CG481_015915	COG3854	ATPases associated with a variety of cellular activities
CG481_015935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG481_015940	COG0006	proline dipeptidase activity
CG481_015945	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG481_015955	COG3872	metal-dependent enzyme
CG481_015965	COG1321	iron dependent repressor
CG481_015980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG481_015990	COG1609	Transcriptional regulator
CG481_016000	COG2076	Multidrug Resistance protein
CG481_016005	COG2076	Multidrug Resistance protein
CG481_016030	COG1131	(ABC) transporter
CG481_016035	COG1725	Transcriptional regulator
CG481_016050	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG481_016055	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG481_016060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG481_016065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG481_016095	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG481_016120	COG1459	type II secretion system
CG481_016165	COG1396	sequence-specific DNA binding
CG481_016195	COG4824	toxin secretion phage lysis holin
CG481_016275	COG3728	DNA packaging
CG481_016285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG481_016405	COG1396	sequence-specific DNA binding
CG481_016420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG481_016455	COG1078	dGTPase activity
CG481_016470	COG1410	methionine synthase
CG481_016470	COG0646	methionine synthase
CG481_016475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CG481_016475	COG0646	methionine synthase
CG481_016480	COG0626	cystathionine gamma-synthase activity
CG481_016485	COG0626	cystathionine gamma-synthase activity
CG481_016515	COG1940	carbohydrate kinase activity
CG481_016520	COG4483	Protein conserved in bacteria
CG481_016525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CG481_016530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG481_016535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CG481_016540	COG0704	Plays a role in the regulation of phosphate uptake
CG481_016545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CG481_016550	COG0581	inorganic phosphate transmembrane transporter activity
CG481_016555	COG0573	inorganic phosphate transmembrane transporter activity
CG481_016560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG481_016570	COG0477	Major facilitator Superfamily
CG481_016575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG481_016595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG481_016600	COG0735	belongs to the Fur family
CG481_016605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG481_016610	COG1121	(ABC) transporter
CG481_016615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG481_016625	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CG481_016640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CG481_016645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CG481_016650	COG2384	SAM-dependent methyltransferase
CG481_016660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG481_016665	COG0358	DNA primase activity
CG481_016670	COG1671	Belongs to the UPF0178 family
CG481_016675	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CG481_016680	COG0517	IMP dehydrogenase activity
CG481_016685	COG1381	Involved in DNA repair and RecF pathway recombination
CG481_016695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG481_016705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG481_016710	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CG481_016715	COG1480	7TM receptor with intracellular HD hydrolase
CG481_016720	COG1702	phosphate starvation-inducible protein PhoH
CG481_016735	COG1610	YqeY-like protein
CG481_016740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG481_016745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG481_016750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG481_016755	COG2264	protein methyltransferase activity
CG481_016760	COG0484	heat shock protein binding
CG481_016765	COG0443	Heat shock 70 kDa protein
CG481_016770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG481_016775	COG1420	regulation of RNA biosynthetic process
CG481_016780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG481_016785	COG1733	regulation of RNA biosynthetic process
CG481_016790	COG0693	protein deglycase activity
CG481_016795	COG0481	GTPase activity
CG481_016805	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CG481_016810	COG0268	Binds directly to 16S ribosomal RNA
CG481_016815	COG1466	dna polymerase III delta subunit
CG481_016825	COG0658	competence protein
CG481_016825	COG2333	competence protein COMEC
CG481_016830	COG2131	deaminase
CG481_016835	COG1596	polysaccharide export
CG481_016835	COG1555	photosystem II stabilization
CG481_016840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG481_016845	COG2226	methyltransferase
CG481_016850	COG0799	negative regulation of ribosome biogenesis
CG481_016855	COG1713	HD superfamily hydrolase involved in NAD metabolism
CG481_016860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG481_016865	COG1534	Rna-binding protein
CG481_016870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG481_016875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CG481_016880	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CG481_016890	COG0688	phosphatidylethanolamine metabolic process
CG481_016895	COG1191	sigma factor activity
CG481_016905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG481_016910	COG2357	RelA SpoT domain protein
CG481_016915	COG1785	Belongs to the alkaline phosphatase family
CG481_016920	COG0456	acetyltransferase
CG481_016925	COG2267	carboxylic ester hydrolase activity
CG481_016950	COG3186	Phenylalanine-4-hydroxylase
CG481_016955	COG2154	pterin-4-alpha-carbinolamine dehydratase
CG481_016960	COG2514	catechol 2,3-dioxygenase activity
CG481_016965	COG2259	Doxx family
CG481_016985	COG1609	Transcriptional regulator
CG481_016995	COG0626	cystathionine gamma-synthase activity
CG481_017000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG481_017005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CG481_017010	COG2226	methyltransferase
CG481_017030	COG0768	penicillin binding
CG481_017040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG481_017045	COG0572	uridine kinase
CG481_017065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG481_017075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG481_017080	COG4472	Bacterial protein of unknown function (DUF965)
CG481_017085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG481_017090	COG0628	permease
CG481_017115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CG481_017125	COG0482	sulfurtransferase activity
CG481_017130	COG1104	cysteine desulfurase activity
CG481_017135	COG1959	2 iron, 2 sulfur cluster binding
CG481_017140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG481_017160	COG2207	Transcriptional regulator
CG481_017170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CG481_017180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG481_017185	COG0124	histidyl-tRNA synthetase
CG481_017205	COG1490	D-aminoacyl-tRNA deacylase activity
CG481_017210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG481_017215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG481_017220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG481_017220	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CG481_017225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG481_017230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG481_017230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG481_017240	COG2244	polysaccharide biosynthetic process
CG481_017265	COG1862	Preprotein translocase
CG481_017270	COG0343	queuine tRNA-ribosyltransferase activity
CG481_017275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG481_017285	COG2255	four-way junction helicase activity
CG481_017290	COG0632	four-way junction helicase activity
CG481_017295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CG481_017315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CG481_017320	COG0157	Belongs to the NadC ModD family
CG481_017325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CG481_017330	COG1104	cysteine desulfurase activity
CG481_017335	COG1827	regulation of RNA biosynthetic process
CG481_017340	COG2258	MOSC domain
CG481_017345	COG0077	Prephenate dehydratase
CG481_017350	COG0577	efflux transmembrane transporter activity
CG481_017355	COG0577	efflux transmembrane transporter activity
CG481_017360	COG1136	(ABC) transporter
CG481_017365	COG5002	protein histidine kinase activity
CG481_017370	COG0745	RESPONSE REGULATOR receiver
CG481_017380	COG3290	protein histidine kinase activity
CG481_017385	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG481_017390	COG2868	ribosomal protein
CG481_017400	COG1530	ribonuclease E activity
CG481_017405	COG1994	Peptidase M50
CG481_017410	COG0739	heme binding
CG481_017415	COG2894	cell division
CG481_017430	COG1792	Involved in formation and maintenance of cell shape
CG481_017435	COG1077	Cell shape determining protein MreB Mrl
CG481_017455	COG0424	maF-like protein
CG481_017465	COG0285	dihydrofolate synthase activity
CG481_017495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG481_017500	COG0113	porphobilinogen synthase activity
CG481_017505	COG1587	Uroporphyrinogen-III synthase
CG481_017510	COG0181	hydroxymethylbilane synthase activity
CG481_017515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG481_017520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CG481_017525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG481_017535	COG0470	DNA polymerase III
CG481_017535	COG1067	ATP-dependent peptidase activity
CG481_017540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CG481_017545	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG481_017570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG481_017570	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_017570	COG4221	oxidoreductase activity
CG481_017570	COG3321	synthase
CG481_017595	COG1309	transcriptional regulator
CG481_017615	COG0622	Phosphoesterase
CG481_017625	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG481_017630	COG5401	PFAM Sporulation and spore germination
CG481_017640	COG2197	response regulator
CG481_017680	COG2197	response regulator
CG481_017690	COG1959	2 iron, 2 sulfur cluster binding
CG481_017695	COG1668	transmembrane transport
CG481_017700	COG4152	abc transporter atp-binding protein
CG481_017705	COG1360	Flagellar Motor Protein
CG481_017710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG481_017720	COG1876	peptidase activity
CG481_017730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CG481_017735	COG1053	succinate dehydrogenase
CG481_017740	COG2009	succinate dehydrogenase
CG481_017745	COG1719	4-vinyl reductase, 4VR
CG481_017760	COG3118	belongs to the thioredoxin family
CG481_017765	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CG481_017770	COG2086	electron transfer activity
CG481_017775	COG1024	Enoyl-CoA hydratase
CG481_017780	COG1309	transcriptional regulator
CG481_017795	COG2318	DinB family
CG481_017815	COG1131	(ABC) transporter
CG481_017820	COG2205	protein histidine kinase activity
CG481_017825	COG0745	RESPONSE REGULATOR receiver
CG481_017835	COG4895	conserved protein (DUF2196)
CG481_017840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CG481_017845	COG1114	Component of the transport system for branched-chain amino acids
CG481_017850	COG1187	pseudouridine synthase activity
CG481_017860	COG1193	negative regulation of DNA recombination
CG481_017865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CG481_017865	COG1796	DNA polymerase
CG481_017870	COG1286	toxin biosynthetic process
CG481_017875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CG481_017900	COG0017	Asparaginyl-tRNA synthetase
CG481_017905	COG0072	phenylalanine-tRNA ligase activity
CG481_017905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG481_017910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CG481_017915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG481_017925	COG1418	mRNA catabolic process
CG481_017940	COG2814	Major facilitator Superfamily
CG481_017945	COG1566	PFAM secretion protein HlyD family protein
CG481_017950	COG1309	transcriptional regulator
CG481_017955	COG1363	Peptidase, m42
CG481_017965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CG481_017970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CG481_017975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CG481_017980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG481_017990	COG1484	DNA-dependent DNA replication
CG481_017995	COG3611	Membrane attachment protein
CG481_018000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG481_018005	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CG481_018015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG481_018025	COG1971	Probably functions as a manganese efflux pump
CG481_018035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG481_018035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG481_018040	COG5002	protein histidine kinase activity
CG481_018045	COG0745	RESPONSE REGULATOR receiver
CG481_018055	COG0039	L-malate dehydrogenase activity
CG481_018060	COG0538	isocitrate dehydrogenase activity
CG481_018065	COG0372	Belongs to the citrate synthase family
CG481_018070	COG2707	UPF0756 membrane protein
CG481_018075	COG0628	permease
CG481_018080	COG3030	protein affecting phage T7 exclusion by the F plasmid
CG481_018090	COG0205	6-phosphofructokinase activity
CG481_018095	COG0825	malonyl-CoA metabolic process
CG481_018100	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CG481_018105	COG1725	Transcriptional regulator
CG481_018110	COG0281	malic enzyme
CG481_018115	COG0587	DNA-directed DNA polymerase activity
CG481_018130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CG481_018140	COG4109	DRTGG domain
CG481_018145	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CG481_018150	COG0006	proline dipeptidase activity
CG481_018175	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_018180	COG0589	response to stress
CG481_018205	COG0165	Argininosuccinate lyase
CG481_018210	COG0137	argininosuccinate synthase activity
CG481_018220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG481_018230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CG481_018235	COG0827	DNA restriction-modification system
CG481_018240	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CG481_018245	COG3874	Sporulation protein YtfJ
CG481_018255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CG481_018260	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CG481_018265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG481_018275	COG0301	tRNA thio-modification
CG481_018280	COG1104	cysteine desulfurase activity
CG481_018285	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CG481_018290	COG0583	DNA-binding transcription factor activity
CG481_018295	COG0697	spore germination
CG481_018300	COG1309	transcriptional regulator
CG481_018305	COG1956	GAF domain-containing protein
CG481_018310	COG0626	cystathionine gamma-synthase activity
CG481_018320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG481_018340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CG481_018350	COG1595	DNA-templated transcription, initiation
CG481_018360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG481_018365	COG0454	-acetyltransferase
CG481_018370	COG0517	IMP dehydrogenase activity
CG481_018375	COG0123	including yeast histone deacetylase and acetoin utilization protein
CG481_018380	COG1970	mechanosensitive ion channel activity
CG481_018390	COG1609	Transcriptional regulator
CG481_018400	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG481_018400	COG1605	Chorismate mutase
CG481_018405	COG3118	belongs to the thioredoxin family
CG481_018415	COG2309	aminopeptidase activity
CG481_018430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG481_018440	COG1674	ftsk spoiiie
CG481_018450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG481_018455	COG4848	Belongs to the UPF0354 family
CG481_018460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG481_018465	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CG481_018475	COG0675	Transposase, IS605 OrfB family
CG481_018485	COG1363	Peptidase, m42
CG481_018495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG481_018500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG481_018510	COG0510	thiamine kinase activity
CG481_018515	COG1523	belongs to the glycosyl hydrolase 13 family
CG481_018525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG481_018530	COG1349	DNA-binding transcription factor activity
CG481_018535	COG1187	pseudouridine synthase activity
CG481_018545	COG2081	HI0933 family
CG481_018550	COG2814	Major facilitator Superfamily
CG481_018560	COG3832	glyoxalase III activity
CG481_018580	COG0463	Glycosyl transferase, family 2
CG481_018640	COG1329	Transcriptional regulator
CG481_018650	COG2223	nitrite transmembrane transporter activity
CG481_018660	COG0314	molybdopterin synthase activity
CG481_018665	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG481_018670	COG0303	'Molybdopterin
CG481_018675	COG0315	cyclic pyranopterin monophosphate synthase activity
CG481_018680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG481_018685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG481_018690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG481_018695	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CG481_018700	COG1140	nitrate reductase beta subunit
CG481_018705	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CG481_018710	COG2181	nitrate reductase activity
CG481_018725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG481_018735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG481_018770	COG0495	leucyl-tRNA aminoacylation
CG481_018775	COG2814	Major facilitator Superfamily
CG481_018785	COG1136	(ABC) transporter
CG481_018790	COG0346	lactoylglutathione lyase activity
CG481_018805	COG1242	4 iron, 4 sulfur cluster binding
CG481_018810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CG481_018815	COG1121	(ABC) transporter
CG481_018825	COG1794	racemase activity, acting on amino acids and derivatives
CG481_018835	COG2378	regulation of single-species biofilm formation
CG481_018860	COG0746	molybdenum cofactor guanylyltransferase activity
CG481_018885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG481_018895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CG481_018940	COG3409	Peptidoglycan-binding domain 1 protein
CG481_018940	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG481_018950	COG1368	sulfuric ester hydrolase activity
CG481_018965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG481_018970	COG1116	anion transmembrane transporter activity
CG481_018975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG481_018990	COG0494	nUDIX hydrolase
CG481_019000	COG1854	S-ribosylhomocysteine lyase activity
CG481_019005	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG481_019010	COG0288	reversible hydration of carbon dioxide
CG481_019015	COG1271	oxidase subunit
CG481_019020	COG1294	oxidase, subunit
CG481_019050	COG1842	Phage shock protein A
CG481_019095	COG1597	lipid kinase activity
CG481_019100	COG0586	Pfam SNARE associated Golgi protein
CG481_019105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG481_019110	COG1136	(ABC) transporter
CG481_019120	COG0745	RESPONSE REGULATOR receiver
CG481_019125	COG2205	protein histidine kinase activity
CG481_019130	COG0577	efflux transmembrane transporter activity
CG481_019135	COG1136	(ABC) transporter
CG481_019155	COG4948	Mandelate Racemase Muconate Lactonizing
CG481_019160	COG0318	PFAM AMP-dependent synthetase and ligase
CG481_019165	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG481_019170	COG0596	Alpha beta hydrolase
CG481_019175	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CG481_019180	COG1169	isochorismate synthase
CG481_019185	COG1575	Belongs to the MenA family. Type 1 subfamily
CG481_019190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CG481_019195	COG1278	Cold shock
CG481_019215	COG0058	SHG alpha-glucan phosphorylase activity
CG481_019220	COG0297	glycogen (starch) synthase activity
CG481_019225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG481_019230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG481_019235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG481_019240	COG0039	L-malate dehydrogenase activity
CG481_019335	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG481_019370	COG1285	pathogenesis
CG481_019375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG481_019385	COG0166	Belongs to the GPI family
CG481_019395	COG2155	Conserved Protein
CG481_019400	COG1098	S1 RNA binding domain
CG481_019405	COG0436	Aminotransferase
CG481_019410	COG1522	sequence-specific DNA binding
CG481_019415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG481_019420	COG2267	carboxylic ester hydrolase activity
CG481_019430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CG481_019435	COG2032	superoxide dismutase activity
CG481_019445	COG5018	Exonuclease
CG481_019450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG481_019455	COG0423	glycine-tRNA ligase activity
CG481_019470	COG2050	protein possibly involved in aromatic compounds catabolism
CG481_019480	COG1268	BioY protein
CG481_019485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG481_019490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG481_019500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG481_019510	COG3584	3D domain protein
CG481_019530	COG1252	NADH dehydrogenase
CG481_019535	COG0492	ferredoxin-NADP+ reductase activity
CG481_019550	COG1683	Conserved Protein
CG481_019560	COG0316	Belongs to the HesB IscA family
CG481_019565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CG481_019570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG481_019580	COG1252	NADH dehydrogenase
CG481_019585	COG2824	Alkylphosphonate utilization operon protein PhnA
CG481_019595	COG3655	Transcriptional regulator
CG481_019610	COG4837	Protein of unknown function (DUF1462)
CG481_019615	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CG481_019620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG481_019625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CG481_019630	COG0647	UMP catabolic process
CG481_019640	COG2445	Protein of unknown function DUF86
CG481_019645	COG1494	fructose-1,6-bisphosphatase
CG481_019655	COG4470	Protein conserved in bacteria
CG481_019665	COG0789	Transcriptional regulator
CG481_019670	COG4377	Putative membrane peptidase family (DUF2324)
CG481_019685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CG481_019690	COG0739	heme binding
CG481_019700	COG3377	Domain of unknown function (DUF1805)
CG481_019705	COG0737	Belongs to the 5'-nucleotidase family
CG481_019725	COG0719	Fe-S assembly protein
CG481_019730	COG0822	iron-sulfur transferase activity
CG481_019735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG481_019740	COG0719	Fe-S assembly protein
CG481_019745	COG0396	ATPase activity
CG481_019750	COG1464	Belongs to the NlpA lipoprotein family
CG481_019755	COG2011	ABC-type metal ion transport system permease component
CG481_019770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG481_019775	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CG481_019780	COG0509	glycine decarboxylation via glycine cleavage system
CG481_019785	COG1393	Belongs to the ArsC family
CG481_019830	COG1960	acyl-CoA dehydrogenase activity
CG481_019835	COG0183	Belongs to the thiolase family
CG481_019840	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG481_019840	COG1024	Enoyl-CoA hydratase
CG481_019850	COG1686	Belongs to the peptidase S11 family
CG481_019875	COG0011	TIGRFAM Protein of
CG481_019880	COG0840	transmembrane signaling receptor activity
CG481_019900	COG0531	amino acid
CG481_019905	COG0706	membrane insertase activity
CG481_019915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG481_019925	COG5002	protein histidine kinase activity
CG481_019930	COG0745	RESPONSE REGULATOR receiver
CG481_019945	COG1131	(ABC) transporter
CG481_019955	COG0586	Pfam SNARE associated Golgi protein
CG481_019965	COG1376	ErfK ybiS ycfS ynhG family protein
CG481_019975	COG5002	protein histidine kinase activity
CG481_019980	COG0840	transmembrane signaling receptor activity
CG481_019985	COG0840	transmembrane signaling receptor activity
CG481_019990	COG2151	metal-sulfur cluster biosynthetic enzyme
CG481_019995	COG3227	Zinc metalloprotease (Elastase)
CG481_020000	COG1741	Belongs to the pirin family
CG481_020015	COG0783	Belongs to the Dps family
CG481_020020	COG1611	Belongs to the LOG family
CG481_020045	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG481_020050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG481_020055	COG1121	(ABC) transporter
CG481_020075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG481_020080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG481_020085	COG1115	amino acid carrier protein
CG481_020090	COG2910	NAD(P)H-binding
CG481_020105	COG1252	NADH dehydrogenase
CG481_020120	COG1595	DNA-templated transcription, initiation
CG481_020130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CG481_020145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG481_020150	COG4977	sequence-specific DNA binding
CG481_020150	COG1917	Cupin 2, conserved barrel domain protein
CG481_020160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CG481_020180	COG0697	spore germination
CG481_020195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CG481_020200	COG0557	exoribonuclease II activity
CG481_020205	COG1647	Serine aminopeptidase, S33
CG481_020210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG481_020215	COG1346	cytolysis
CG481_020225	COG0148	phosphopyruvate hydratase activity
CG481_020230	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CG481_020235	COG0149	triose-phosphate isomerase activity
CG481_020240	COG0126	phosphoglycerate kinase activity
CG481_020245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG481_020260	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CG481_020285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG481_020300	COG2323	membrane
CG481_020310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG481_020315	COG1481	regulation of sporulation
CG481_020320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CG481_020325	COG1660	Displays ATPase and GTPase activities
CG481_020330	COG1051	belongs to the nudix hydrolase family
CG481_020340	COG0492	ferredoxin-NADP+ reductase activity
CG481_020345	COG0457	Tetratricopeptide repeat
CG481_020350	COG0110	maltose O-acetyltransferase activity
CG481_020360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG481_020365	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CG481_020370	COG1950	PFAM Membrane protein of
CG481_020380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG481_020395	COG0789	Transcriptional regulator
CG481_020415	COG0583	DNA-binding transcription factor activity
CG481_020430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG481_020435	COG0793	Belongs to the peptidase S41A family
CG481_020435	COG3409	Peptidoglycan-binding domain 1 protein
CG481_020440	COG2177	Part of the ABC transporter FtsEX involved in
CG481_020445	COG2884	Cell division ATP-binding protein ftsE
CG481_020480	COG1278	Cold shock
CG481_020485	COG1040	competence protein
CG481_020490	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CG481_020495	COG1388	LysM domain
CG481_020495	COG0791	NLP P60 protein
CG481_020500	COG1733	regulation of RNA biosynthetic process
CG481_020505	COG1307	EDD domain protein, DegV family
CG481_020510	COG1739	Uncharacterized protein family UPF0029
CG481_020515	COG1316	TRANSCRIPTIONal
CG481_020535	COG0457	Tetratricopeptide repeat
CG481_020565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CG481_020575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG481_020585	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CG481_020585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CG481_020600	COG1486	melibiose metabolic process
CG481_020605	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG481_020620	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG481_020625	COG1301	dicarboxylic acid transport
CG481_020630	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CG481_020640	COG1271	oxidase subunit
CG481_020645	COG1294	oxidase, subunit
CG481_020650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CG481_020655	COG1620	l-lactate permease
CG481_020660	COG2389	metal-binding protein
CG481_020670	COG1368	sulfuric ester hydrolase activity
CG481_020680	COG0791	NLP P60 protein
CG481_020680	COG1388	LysM domain
CG481_020685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG481_020695	COG1215	transferase activity, transferring glycosyl groups
CG481_020705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG481_020710	COG1388	LysM domain
CG481_020710	COG3584	3D domain protein
CG481_020725	COG4715	Zinc finger, swim domain protein
CG481_020730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG481_020770	COG0577	efflux transmembrane transporter activity
CG481_020775	COG1136	(ABC) transporter
CG481_020810	COG3850	Histidine kinase
CG481_020810	COG5002	protein histidine kinase activity
CG481_020815	COG0745	RESPONSE REGULATOR receiver
CG481_020820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG481_020830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG481_020835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG481_020840	COG1134	teichoic acid transport
CG481_020845	COG1682	transport, permease protein
CG481_020850	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG481_020860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG481_020865	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG481_020870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CG481_020880	COG1609	Transcriptional regulator
CG481_020890	COG0739	heme binding
CG481_020905	COG3279	Response regulator of the LytR AlgR family
CG481_020910	COG2385	sporulation resulting in formation of a cellular spore
CG481_020925	COG4836	Membrane
CG481_020930	COG1007	ATP synthesis coupled electron transport
CG481_020935	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG481_020945	COG0713	ATP synthesis coupled electron transport
CG481_020950	COG0839	Belongs to the complex I subunit 6 family
CG481_020965	COG0649	NAD binding
CG481_020970	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG481_020975	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG481_020980	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG481_020985	COG3300	MHYT domain
CG481_020985	COG5001	Diguanylate cyclase
CG481_020990	COG3300	MHYT domain
CG481_020990	COG5001	Diguanylate cyclase
CG481_021005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG481_021010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG481_021015	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG481_021020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG481_021025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG481_021030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG481_021035	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG481_021060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG481_021065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG481_021075	COG0698	ribose 5-phosphate isomerase
CG481_021095	COG2190	(PTS) system
CG481_021100	COG2259	Doxx family
CG481_021105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG481_021120	COG0009	L-threonylcarbamoyladenylate synthase
CG481_021135	COG2890	protein-(glutamine-N5) methyltransferase activity
CG481_021140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG481_021145	COG1435	thymidine kinase activity
CG481_021155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG481_021160	COG1494	fructose-1,6-bisphosphatase
CG481_021180	COG4821	SIS domain
CG481_021185	COG0504	CTP synthase activity
CG481_021200	COG1960	acyl-CoA dehydrogenase activity
CG481_021205	COG1960	acyl-CoA dehydrogenase activity
CG481_021210	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG481_021215	COG0183	Belongs to the thiolase family
CG481_021220	COG0247	lactate metabolic process
CG481_021220	COG2181	nitrate reductase activity
CG481_021225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG481_021240	COG2197	response regulator
CG481_021245	COG4585	Histidine kinase
CG481_021250	COG0842	Transport permease protein
CG481_021255	COG1131	(ABC) transporter
CG481_021260	COG0024	Methionine aminopeptidase
CG481_021265	COG2234	aminopeptidase activity
CG481_021280	COG4506	Protein conserved in bacteria
CG481_021285	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG481_021305	COG0010	Belongs to the arginase family
CG481_021310	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CG481_021315	COG2814	Major facilitator Superfamily
CG481_021320	COG0789	Transcriptional regulator
CG481_021325	COG0584	glycerophosphoryl diester phosphodiesterase
CG481_021330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG481_021335	COG2801	Transposase and inactivated derivatives
CG481_021340	COG1404	Belongs to the peptidase S8 family
CG481_021360	COG1994	Peptidase M50
CG481_021370	COG1078	dGTPase activity
CG481_021375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG481_021380	COG1120	ATPase activity
CG481_021385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG481_021390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG481_021395	COG4844	belongs to the
CG481_021410	COG0280	phosphate acetyltransferase
CG481_021425	COG3773	Cell wall hydrolase
CG481_021435	COG2363	Small membrane protein
CG481_021445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG481_021450	COG2233	PERMEase
CG481_021455	COG0561	phosphatase activity
CG481_021460	COG2814	Major facilitator Superfamily
CG481_021465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG481_021470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG481_021475	COG1131	(ABC) transporter
CG481_021485	COG0460	homoserine dehydrogenase
CG481_021490	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CG481_021505	COG0351	phosphomethylpyrimidine kinase
CG481_021515	COG1966	Carbon starvation protein
CG481_021520	COG3279	Response regulator of the LytR AlgR family
CG481_021530	COG0477	Major facilitator Superfamily
CG481_021540	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CG481_021545	COG0438	transferase activity, transferring glycosyl groups
CG481_021560	COG0840	transmembrane signaling receptor activity
CG481_021585	COG1607	acyl-coa hydrolase
CG481_021590	COG1216	Glycosyl transferase, family 2
CG481_021605	COG0463	Glycosyl transferase, family 2
CG481_021620	COG0463	Glycosyl transferase, family 2
CG481_021625	COG0488	(ABC) transporter
CG481_021630	COG1309	transcriptional regulator
CG481_021635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG481_021640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG481_021640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG481_021645	COG0628	permease
CG481_021650	COG1346	cytolysis
CG481_021660	COG3279	Response regulator of the LytR AlgR family
CG481_021665	COG3275	phosphorelay sensor kinase activity
CG481_021670	COG2814	Major facilitator Superfamily
CG481_021675	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CG481_021680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG481_021690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG481_021695	COG3711	transcriptional antiterminator
CG481_021695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG481_021785	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG481_021795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG481_021800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CG481_021805	COG4853	Protein conserved in bacteria
CG481_021815	COG5002	protein histidine kinase activity
CG481_021820	COG0745	RESPONSE REGULATOR receiver
CG481_021845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG481_021850	COG0305	Participates in initiation and elongation during chromosome replication
CG481_021855	COG0359	binds to the 23S rRNA
CG481_021865	COG4241	membrane
CG481_021870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CG481_021875	COG0629	single-stranded DNA binding
CG481_021880	COG0360	Binds together with S18 to 16S ribosomal RNA
CG481_021885	COG0012	GTP binding
CG481_021890	COG4481	Protein conserved in bacteria
CG481_021895	COG0668	transmembrane transport
CG481_021910	COG1192	Involved in chromosome partitioning
CG481_021915	COG1475	DNA binding
CG481_021920	COG0357	Ribosomal RNA small subunit methyltransferase G
CG481_021925	COG0445	tRNA wobble uridine modification
CG481_021930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG481_021935	COG1847	R3H domain protein
CG481_021940	COG0706	membrane insertase activity
CG481_021945	COG0594	ribonuclease P activity
CG481_021955	COG1073	alpha beta
CG481_021965	COG2197	response regulator
CG481_021970	COG1476	TRANSCRIPTIONal
CG481_022145	COG2003	Belongs to the UPF0758 family
CG481_022160	COG3209	COG3209 Rhs family protein
CG481_022200	COG0457	Tetratricopeptide repeat
CG481_022270	COG1028	Short-chain dehydrogenase reductase Sdr
CG481_022290	COG0583	DNA-binding transcription factor activity
CG481_022335	COG0791	NLP P60 protein
CG481_022335	COG0741	lytic transglycosylase activity
CG481_022420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG481_022505	COG4974	Belongs to the 'phage' integrase family
CG481_022540	COG4166	transmembrane transport
CG481_022550	COG0457	Tetratricopeptide repeat
CG481_022590	COG1192	Involved in chromosome partitioning