locus-tag	class	description
CG482_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG482_000010	COG0592	DNA-directed DNA polymerase activity
CG482_000015	COG2501	S4 domain
CG482_000020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG482_000025	COG0187	DNA topoisomerase II activity
CG482_000030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG482_000065	COG0517	IMP dehydrogenase activity
CG482_000065	COG0516	GMP reductase activity
CG482_000070	COG1686	Belongs to the peptidase S11 family
CG482_000075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CG482_000080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CG482_000085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG482_000100	COG1428	Deoxynucleoside kinase
CG482_000105	COG1428	Deoxynucleoside kinase
CG482_000110	COG1335	isochorismatase
CG482_000115	COG0590	tRNA wobble adenosine to inosine editing
CG482_000125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG482_000130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG482_000135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG482_000180	COG1982	Orn Lys Arg decarboxylase major
CG482_000185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG482_000190	COG0470	DNA polymerase III
CG482_000195	COG1774	PSP1 C-terminal conserved region
CG482_000200	COG4467	Involved in initiation control of chromosome replication
CG482_000205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CG482_000215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CG482_000220	COG2002	toxin-antitoxin pair type II binding
CG482_000230	COG0084	hydrolase, TatD family'
CG482_000240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG482_000250	COG4466	Protein conserved in bacteria
CG482_000260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CG482_000265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG482_000270	COG0251	oxidation-reduction process
CG482_000275	COG2088	sporulation resulting in formation of a cellular spore
CG482_000280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG482_000285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CG482_000290	COG0193	aminoacyl-tRNA hydrolase activity
CG482_000300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG482_000305	COG2002	toxin-antitoxin pair type II binding
CG482_000310	COG2244	polysaccharide biosynthetic process
CG482_000315	COG3956	TIGRFAM MazG family protein
CG482_000320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CG482_000340	COG1098	S1 RNA binding domain
CG482_000355	COG2208	phosphoserine phosphatase activity
CG482_000370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG482_000375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CG482_000380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG482_000385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG482_000395	COG0512	Glutamine amidotransferase of anthranilate synthase
CG482_000400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG482_000405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CG482_000410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CG482_000415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CG482_000420	COG1396	sequence-specific DNA binding
CG482_000425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG482_000430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG482_000465	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_000515	COG3880	PFAM UvrB UvrC protein
CG482_000520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CG482_000525	COG0542	response to heat
CG482_000530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CG482_000540	COG4956	integral membrane protein (PIN domain superfamily)
CG482_000545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG482_000550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG482_000555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG482_000560	COG1045	serine acetyltransferase
CG482_000565	COG0215	cysteine-tRNA ligase activity
CG482_000575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG482_000580	COG3688	RNA-binding protein containing a PIN domain
CG482_000600	COG0250	Participates in transcription elongation, termination and antitermination
CG482_000610	COG0081	regulation of translation
CG482_000615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG482_000620	COG0222	ribosome binding
CG482_000625	COG2813	Specifically methylates the guanine in position
CG482_000635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG482_000640	COG1358	cellular component organization or biogenesis
CG482_000645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CG482_000650	COG0049	tRNA binding
CG482_000655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG482_000660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG482_000670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CG482_000675	COG0088	Forms part of the polypeptide exit tunnel
CG482_000680	COG0089	rRNA binding
CG482_000685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CG482_000690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG482_000695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CG482_000700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CG482_000705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CG482_000715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG482_000720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG482_000725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CG482_000730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CG482_000740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG482_000745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CG482_000750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CG482_000755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CG482_000760	COG1841	ribosomal large subunit assembly
CG482_000765	COG0200	Binds to the 23S rRNA
CG482_000770	COG0201	protein transport
CG482_000775	COG0563	adenylate kinase activity
CG482_000780	COG0024	Methionine aminopeptidase
CG482_000790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG482_000800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG482_000805	COG0202	RNA polymerase activity
CG482_000820	COG1122	ATPase activity
CG482_000825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG482_000835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG482_000840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CG482_000850	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG482_000855	COG0489	protein tyrosine kinase activity
CG482_000865	COG2194	sulfuric ester hydrolase activity
CG482_000870	COG0726	polysaccharide deacetylase
CG482_000950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CG482_000960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG482_001025	COG0457	Tetratricopeptide repeat
CG482_001050	COG1266	CAAX protease self-immunity
CG482_001125	COG3681	Belongs to the UPF0597 family
CG482_001130	COG3681	Belongs to the UPF0597 family
CG482_001155	COG2814	Major facilitator Superfamily
CG482_001165	COG0601	transmembrane transport
CG482_001170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG482_001175	COG0444	Belongs to the ABC transporter superfamily
CG482_001180	COG4608	Belongs to the ABC transporter superfamily
CG482_001185	COG4166	transmembrane transport
CG482_001205	COG1309	transcriptional regulator
CG482_001215	COG0656	L-ascorbic acid biosynthetic process
CG482_001220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG482_001230	COG4149	molybdate abc transporter
CG482_001235	COG0725	ABC transporter, periplasmic molybdate-binding protein
CG482_001240	COG1910	domain protein
CG482_001245	COG0204	Acyl-transferase
CG482_001250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_001255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG482_001255	COG1648	precorrin-2 dehydrogenase activity
CG482_001265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG482_001265	COG1587	Uroporphyrinogen-III synthase
CG482_001270	COG2146	nitrite reductase [NAD(P)H] activity
CG482_001275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG482_001305	COG4585	Histidine kinase
CG482_001310	COG2197	response regulator
CG482_001315	COG1131	(ABC) transporter
CG482_001320	COG0842	Transport permease protein
CG482_001320	COG1511	domain protein
CG482_001325	COG0842	Transport permease protein
CG482_001335	COG0747	negative chemotaxis
CG482_001340	COG0601	transmembrane transport
CG482_001350	COG0444	Belongs to the ABC transporter superfamily
CG482_001355	COG4608	Belongs to the ABC transporter superfamily
CG482_001360	COG0561	phosphatase activity
CG482_001380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CG482_001385	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG482_001395	COG2814	Major facilitator Superfamily
CG482_001400	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG482_001405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CG482_001415	COG0705	Rhomboid family
CG482_001415	COG0457	Tetratricopeptide repeat
CG482_001420	COG0736	holo-[acyl-carrier-protein] synthase activity
CG482_001425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG482_001435	COG0864	Transcriptional regulator
CG482_001440	COG2337	Toxic component of a toxin-antitoxin (TA) module
CG482_001445	COG2183	response to ionizing radiation
CG482_001455	COG3091	SprT-like family
CG482_001495	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_001545	COG0802	atpase or kinase
CG482_001550	COG1214	PFAM Peptidase M22, glycoprotease
CG482_001555	COG0456	acetyltransferase
CG482_001565	COG0488	(ABC) transporter
CG482_001570	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CG482_001580	COG1266	CAAX protease self-immunity
CG482_001585	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CG482_001590	COG0459	protein refolding
CG482_001595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG482_001595	COG0519	Catalyzes the synthesis of GMP from XMP
CG482_001600	COG2252	PERMEase
CG482_001610	COG5002	protein histidine kinase activity
CG482_001680	COG2205	protein histidine kinase activity
CG482_001685	COG0745	RESPONSE REGULATOR receiver
CG482_001705	COG0697	spore germination
CG482_001730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG482_001735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG482_001740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG482_001745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG482_001750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG482_001755	COG0047	phosphoribosylformylglycinamidine synthase activity
CG482_001760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG482_001765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CG482_001770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG482_001775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG482_001780	COG0138	bifunctional purine biosynthesis protein purh
CG482_001785	COG0151	Belongs to the GarS family
CG482_001795	COG0583	DNA-binding transcription factor activity
CG482_001815	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CG482_001820	COG0210	DNA helicase
CG482_001825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CG482_001830	COG4851	CamS sex pheromone cAM373 precursor
CG482_001840	COG1012	belongs to the aldehyde dehydrogenase family
CG482_001845	COG1335	isochorismatase
CG482_001855	COG2011	ABC-type metal ion transport system permease component
CG482_001875	COG4682	membrane
CG482_001880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG482_001885	COG0154	amidase activity
CG482_001890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG482_001895	COG1597	lipid kinase activity
CG482_001900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG482_001905	COG0546	phosphoglycolate phosphatase activity
CG482_001910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG482_001920	COG0531	amino acid
CG482_001925	COG1012	belongs to the aldehyde dehydrogenase family
CG482_001930	COG2076	Multidrug Resistance protein
CG482_001935	COG2309	aminopeptidase activity
CG482_001945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_001950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG482_001955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG482_001970	COG0450	alkyl hydroperoxide reductase
CG482_001995	COG0714	Associated with various cellular activities
CG482_002030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_002035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_002040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG482_002045	COG0492	ferredoxin-NADP+ reductase activity
CG482_002055	COG0166	Belongs to the GPI family
CG482_002060	COG5002	protein histidine kinase activity
CG482_002090	COG2814	Major facilitator Superfamily
CG482_002095	COG0723	plastoquinol--plastocyanin reductase activity
CG482_002095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG482_002105	COG0765	amino acid transport
CG482_002110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG482_002115	COG1126	abc transporter atp-binding protein
CG482_002120	COG0840	transmembrane signaling receptor activity
CG482_002130	COG2235	arginine
CG482_002145	COG0549	Belongs to the carbamate kinase family
CG482_002160	COG0366	Alpha amylase catalytic
CG482_002165	COG1263	PTS System
CG482_002165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_002165	COG2190	(PTS) system
CG482_002185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_002190	COG4605	iron ion homeostasis
CG482_002195	COG4604	ABC transporter, ATP-binding protein
CG482_002200	COG4607	ABC-type enterochelin transport system periplasmic component
CG482_002205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CG482_002210	COG0352	thiamine-phosphate diphosphorylase activity
CG482_002215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CG482_002235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG482_002245	COG1116	anion transmembrane transporter activity
CG482_002280	COG2270	Major facilitator Superfamily
CG482_002305	COG2310	stress, protein
CG482_002310	COG2310	stress, protein
CG482_002315	COG2310	stress, protein
CG482_002320	COG0861	Integral membrane protein TerC family
CG482_002330	COG3853	Toxic anion resistance protein (TelA)
CG482_002340	COG4840	Belongs to the UPF0435 family
CG482_002345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG482_002355	COG1295	ribonuclease BN
CG482_002360	COG2217	Heavy metal translocating P-type atpase
CG482_002365	COG0697	spore germination
CG482_002375	COG0681	Belongs to the peptidase S26 family
CG482_002385	COG0586	Pfam SNARE associated Golgi protein
CG482_002410	COG0535	radical SAM domain protein
CG482_002430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CG482_002465	COG2066	Belongs to the glutaminase family
CG482_002470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_002470	COG1263	PTS System
CG482_002485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG482_002485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG482_002495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CG482_002500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG482_002515	COG0402	S-adenosylhomocysteine deaminase activity
CG482_002520	COG2137	regulation of response to DNA damage stimulus
CG482_002545	COG1988	membrane-bound metal-dependent
CG482_002550	COG1194	a g-specific adenine glycosylase
CG482_002575	COG3557	Belongs to the UPF0374 family
CG482_002580	COG1132	(ABC) transporter
CG482_002585	COG4129	membrane
CG482_002590	COG0070	glutamate synthase
CG482_002590	COG0069	glutamate synthase activity
CG482_002590	COG0067	glutamate synthase
CG482_002595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG482_002600	COG4555	ABC transporter
CG482_002620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG482_002625	COG0735	belongs to the Fur family
CG482_002745	COG0457	Tetratricopeptide repeat
CG482_002750	COG0217	transcriptional regulatory protein
CG482_002755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG482_002760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG482_002780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CG482_002790	COG2766	serine protein kinase
CG482_002815	COG1280	lysine exporter protein (LysE YggA)
CG482_002855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG482_002865	COG1585	Membrane protein implicated in regulation of membrane protease activity
CG482_002870	COG2268	Band 7 protein
CG482_002910	COG3290	protein histidine kinase activity
CG482_002915	COG4565	transcriptional regulatory protein
CG482_002920	COG3493	citrate carrier protein
CG482_002925	COG0281	malic enzyme
CG482_002940	COG5002	protein histidine kinase activity
CG482_002945	COG0745	RESPONSE REGULATOR receiver
CG482_002955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CG482_002960	COG3383	formate dehydrogenase (NAD+) activity
CG482_002965	COG2427	Protein of unknown function (DUF1641)
CG482_002975	COG0840	transmembrane signaling receptor activity
CG482_002985	COG0531	amino acid
CG482_003000	COG0640	Transcriptional regulator
CG482_003010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG482_003020	COG3227	Zinc metalloprotease (Elastase)
CG482_003035	COG2217	Heavy metal translocating P-type atpase
CG482_003055	COG2720	vancomycin resistance protein
CG482_003060	COG1316	TRANSCRIPTIONal
CG482_003070	COG1253	flavin adenine dinucleotide binding
CG482_003075	COG1027	Aspartate ammonia-lyase
CG482_003080	COG1620	l-lactate permease
CG482_003100	COG3104	oligopeptide transport
CG482_003105	COG0156	8-amino-7-oxononanoate synthase activity
CG482_003110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG482_003115	COG4548	von Willebrand factor, type A
CG482_003120	COG0714	Associated with various cellular activities
CG482_003125	COG0531	amino acid
CG482_003130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG482_003145	COG1126	abc transporter atp-binding protein
CG482_003150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG482_003155	COG0765	amino acid transport
CG482_003160	COG0765	amino acid transport
CG482_003165	COG0833	amino acid
CG482_003175	COG5002	protein histidine kinase activity
CG482_003190	COG0659	secondary active sulfate transmembrane transporter activity
CG482_003195	COG0589	response to stress
CG482_003205	COG0747	negative chemotaxis
CG482_003215	COG0601	transmembrane transport
CG482_003220	COG4608	Belongs to the ABC transporter superfamily
CG482_003230	COG2271	Major facilitator Superfamily
CG482_003235	COG1846	Transcriptional regulator
CG482_003240	COG0477	Major facilitator Superfamily
CG482_003245	COG1609	Transcriptional regulator
CG482_003250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG482_003255	COG1869	D-ribose catabolic process
CG482_003260	COG1129	ABC transporter
CG482_003265	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG482_003270	COG1879	ABC-type sugar transport system periplasmic component
CG482_003275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CG482_003290	COG3568	Endonuclease Exonuclease Phosphatase
CG482_003315	COG0840	transmembrane signaling receptor activity
CG482_003320	COG3584	3D domain protein
CG482_003320	COG3583	domain protein
CG482_003325	COG1476	TRANSCRIPTIONal
CG482_003355	COG1114	Component of the transport system for branched-chain amino acids
CG482_003365	COG1113	amino acid transport
CG482_003370	COG2153	protein acetylation
CG482_003380	COG0475	glutathione-regulated potassium exporter activity
CG482_003380	COG0569	domain protein
CG482_003395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG482_003400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CG482_003405	COG0833	amino acid
CG482_003410	COG4990	cell redox homeostasis
CG482_003425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_003430	COG0697	spore germination
CG482_003435	COG0531	amino acid
CG482_003450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG482_003455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG482_003460	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG482_003460	COG1918	ferrous iron import across plasma membrane
CG482_003465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG482_003470	COG0573	inorganic phosphate transmembrane transporter activity
CG482_003475	COG0581	inorganic phosphate transmembrane transporter activity
CG482_003480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG482_003520	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_003595	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CG482_003620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG482_003625	COG1116	anion transmembrane transporter activity
CG482_003630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG482_003635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG482_003640	COG0352	thiamine-phosphate diphosphorylase activity
CG482_003645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG482_003650	COG2104	thiamine diphosphate biosynthetic process
CG482_003655	COG2022	thiamine diphosphate biosynthetic process
CG482_003660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG482_003665	COG0351	phosphomethylpyrimidine kinase
CG482_003695	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CG482_003700	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CG482_003705	COG2205	protein histidine kinase activity
CG482_003710	COG2814	Major facilitator Superfamily
CG482_003715	COG1846	Transcriptional regulator
CG482_003725	COG2252	PERMEase
CG482_003730	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_003735	COG1376	ErfK ybiS ycfS ynhG family protein
CG482_003790	COG0778	Nitroreductase
CG482_003800	COG2719	SpoVR family
CG482_003810	COG1316	TRANSCRIPTIONal
CG482_003815	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG482_003830	COG0577	efflux transmembrane transporter activity
CG482_003835	COG1136	(ABC) transporter
CG482_003845	COG1114	Component of the transport system for branched-chain amino acids
CG482_003850	COG3546	catalase activity
CG482_003905	COG0475	glutathione-regulated potassium exporter activity
CG482_003910	COG1737	Transcriptional regulator
CG482_003920	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CG482_003925	COG1263	PTS System
CG482_003925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_003940	COG1522	sequence-specific DNA binding
CG482_003955	COG0531	amino acid
CG482_003965	COG1012	belongs to the aldehyde dehydrogenase family
CG482_003970	COG1132	(ABC) transporter
CG482_003975	COG1132	(ABC) transporter
CG482_003985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG482_003990	COG0765	amino acid transport
CG482_003995	COG1126	abc transporter atp-binding protein
CG482_004010	COG0189	ligase activity
CG482_004015	COG4399	Belongs to the UPF0754 family
CG482_004020	COG3679	Belongs to the UPF0342 family
CG482_004025	COG4585	Histidine kinase
CG482_004030	COG2197	response regulator
CG482_004080	COG2094	Belongs to the DNA glycosylase MPG family
CG482_004085	COG0561	phosphatase activity
CG482_004095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG482_004125	COG2244	polysaccharide biosynthetic process
CG482_004135	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG482_004155	COG1696	Membrane protein involved in D-alanine export
CG482_004170	COG1024	Enoyl-CoA hydratase
CG482_004185	COG1363	Peptidase, m42
CG482_004200	COG2239	Acts as a magnesium transporter
CG482_004210	COG1115	amino acid carrier protein
CG482_004285	COG1476	TRANSCRIPTIONal
CG482_004420	COG3829	transcription factor binding
CG482_004420	COG3290	protein histidine kinase activity
CG482_004445	COG1061	Type III restriction enzyme res subunit
CG482_004485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CG482_004495	COG4638	Rieske (2fe-2S)
CG482_004500	COG1012	belongs to the aldehyde dehydrogenase family
CG482_004505	COG0473	3-isopropylmalate dehydrogenase activity
CG482_004515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_004525	COG1064	alcohol dehydrogenase
CG482_004540	COG3246	L-lysine catabolic process to acetate
CG482_004575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CG482_004585	COG4641	Protein conserved in bacteria
CG482_004600	COG3711	transcriptional antiterminator
CG482_004605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_004605	COG2190	(PTS) system
CG482_004605	COG1263	PTS System
CG482_004610	COG2723	6-phospho-beta-galactosidase activity
CG482_004620	COG2376	Dihydroxyacetone kinase
CG482_004625	COG0393	Putative heavy-metal-binding
CG482_004655	COG0420	3'-5' exonuclease activity
CG482_004660	COG4717	serine-type aminopeptidase activity
CG482_004665	COG3481	metal-dependent phosphohydrolase, HD sub domain
CG482_004680	COG1136	(ABC) transporter
CG482_004690	COG5002	protein histidine kinase activity
CG482_004695	COG0745	RESPONSE REGULATOR receiver
CG482_004705	COG1316	TRANSCRIPTIONal
CG482_004720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CG482_004725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CG482_004730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG482_004735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CG482_004755	COG1846	Transcriptional regulator
CG482_004760	COG4980	gas vesicle protein
CG482_004770	COG0537	adenosine 5'-monophosphoramidase activity
CG482_004775	COG1131	(ABC) transporter
CG482_004780	COG4473	ABC transporter
CG482_004800	COG3402	PFAM membrane-flanked domain
CG482_004810	COG2329	Antibiotic biosynthesis monooxygenase
CG482_004815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_004820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CG482_004860	COG1309	transcriptional regulator
CG482_004870	COG1216	Glycosyl transferase, family 2
CG482_004870	COG0438	transferase activity, transferring glycosyl groups
CG482_004885	COG1609	Transcriptional regulator
CG482_004895	COG1234	tRNA 3'-trailer cleavage
CG482_004900	COG0095	Lipoate-protein ligase
CG482_004910	COG0318	PFAM AMP-dependent synthetase and ligase
CG482_004925	COG2205	protein histidine kinase activity
CG482_004930	COG0745	RESPONSE REGULATOR receiver
CG482_004950	COG0501	Belongs to the peptidase M48B family
CG482_004955	COG0840	transmembrane signaling receptor activity
CG482_004960	COG0697	spore germination
CG482_004980	COG2224	Isocitrate lyase
CG482_004985	COG1278	Cold shock
CG482_004995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG482_005005	COG1396	sequence-specific DNA binding
CG482_005095	COG1598	PFAM Uncharacterised protein family UPF0150
CG482_005215	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG482_005230	COG2207	Transcriptional regulator
CG482_005230	COG3708	Transcriptional regulator
CG482_005265	COG0398	Pfam SNARE associated Golgi protein
CG482_005275	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CG482_005280	COG1074	ATP-dependent DNA helicase activity
CG482_005320	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG482_005340	COG0367	asparagine synthase
CG482_005350	COG0753	catalase activity
CG482_005360	COG1874	Beta-galactosidase
CG482_005360	COG0366	Alpha amylase catalytic
CG482_005365	COG1666	GTP binding
CG482_005370	COG2996	Protein conserved in bacteria
CG482_005385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_005400	COG0561	phosphatase activity
CG482_005425	COG2267	carboxylic ester hydrolase activity
CG482_005440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG482_005445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG482_005450	COG5504	Zn-dependent protease
CG482_005460	COG0180	Tryptophanyl-tRNA synthetase
CG482_005475	COG4166	transmembrane transport
CG482_005480	COG0601	transmembrane transport
CG482_005485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG482_005490	COG0444	Belongs to the ABC transporter superfamily
CG482_005495	COG4608	Belongs to the ABC transporter superfamily
CG482_005500	COG0534	Mate efflux family protein
CG482_005505	COG4166	transmembrane transport
CG482_005525	COG1393	Belongs to the ArsC family
CG482_005530	COG0861	Integral membrane protein TerC family
CG482_005550	COG1164	Oligoendopeptidase f
CG482_005565	COG2346	COG2346, Truncated hemoglobins
CG482_005570	COG4116	CYTH
CG482_005580	COG2357	RelA SpoT domain protein
CG482_005590	COG0564	pseudouridine synthase activity
CG482_005600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG482_005605	COG0772	Belongs to the SEDS family
CG482_005650	COG1216	Glycosyl transferase, family 2
CG482_005670	COG0457	Tetratricopeptide repeat
CG482_005670	COG0463	Glycosyl transferase, family 2
CG482_005690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CG482_005705	COG1091	dTDP-4-dehydrorhamnose reductase activity
CG482_005730	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CG482_005735	COG2382	esterase
CG482_005750	COG5492	domain, Protein
CG482_005755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_005770	COG1620	l-lactate permease
CG482_005775	COG5634	Uncharacterized conserved protein (DUF2278)
CG482_005815	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG482_005820	COG0567	Dehydrogenase, E1 component
CG482_005830	COG0583	DNA-binding transcription factor activity
CG482_005835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG482_005840	COG1012	belongs to the aldehyde dehydrogenase family
CG482_005855	COG0196	riboflavin kinase activity
CG482_005860	COG3162	membrane
CG482_005865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_005870	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG482_005885	COG0457	Tetratricopeptide repeat
CG482_005940	COG0673	inositol 2-dehydrogenase activity
CG482_005970	COG0457	Tetratricopeptide repeat
CG482_005975	COG0582	viral genome integration into host DNA
CG482_006010	COG1686	Belongs to the peptidase S11 family
CG482_006015	COG0681	Belongs to the peptidase S26 family
CG482_006050	COG1012	belongs to the aldehyde dehydrogenase family
CG482_006060	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG482_006065	COG1177	transmembrane transport
CG482_006070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG482_006075	COG0671	phosphoesterase, PA-phosphatase related
CG482_006080	COG2409	Drug exporters of the RND superfamily
CG482_006090	COG0564	pseudouridine synthase activity
CG482_006100	COG2340	Cysteine-rich secretory protein family
CG482_006105	COG0247	lactate metabolic process
CG482_006110	COG0277	FAD linked oxidase domain protein
CG482_006115	COG3835	regulator
CG482_006125	COG0745	RESPONSE REGULATOR receiver
CG482_006130	COG5002	protein histidine kinase activity
CG482_006135	COG2186	Transcriptional regulator
CG482_006140	COG0247	lactate metabolic process
CG482_006145	COG1139	Iron-sulfur cluster binding protein
CG482_006150	COG1556	Lactate utilization protein
CG482_006155	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CG482_006160	COG0584	glycerophosphoryl diester phosphodiesterase
CG482_006170	COG2267	carboxylic ester hydrolase activity
CG482_006175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG482_006185	COG2116	formate transmembrane transporter activity
CG482_006190	COG0861	Integral membrane protein TerC family
CG482_006195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG482_006205	COG2030	dehydratase
CG482_006225	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_006230	COG3243	poly(R)-hydroxyalkanoic acid synthase
CG482_006235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG482_006250	COG1840	ABC-type Fe3 transport system, periplasmic component
CG482_006255	COG3842	ATPase activity
CG482_006265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG482_006270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CG482_006275	COG1349	DNA-binding transcription factor activity
CG482_006280	COG0235	Class ii aldolase
CG482_006290	COG2861	carbohydrate metabolic process
CG482_006300	COG3852	Histidine kinase
CG482_006305	COG1846	Transcriptional regulator
CG482_006325	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CG482_006330	COG0720	synthase
CG482_006340	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG482_006345	COG4873	Protein conserved in bacteria
CG482_006355	COG0456	acetyltransferase
CG482_006375	COG1780	Probably involved in ribonucleotide reductase function
CG482_006390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG482_006395	COG1725	Transcriptional regulator
CG482_006400	COG1131	(ABC) transporter
CG482_006410	COG1131	(ABC) transporter
CG482_006415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG482_006430	COG1522	sequence-specific DNA binding
CG482_006445	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG482_006450	COG2070	2-Nitropropane dioxygenase
CG482_006455	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CG482_006465	COG1696	Membrane protein involved in D-alanine export
CG482_006470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG482_006485	COG0716	FMN binding
CG482_006510	COG1368	sulfuric ester hydrolase activity
CG482_006520	COG3173	Aminoglycoside phosphotransferase
CG482_006535	COG5609	conserved protein (DUF2294)
CG482_006540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG482_006545	COG3002	Belongs to the UPF0753 family
CG482_006550	COG0288	reversible hydration of carbon dioxide
CG482_006555	COG0534	Mate efflux family protein
CG482_006570	COG1846	Transcriptional regulator
CG482_006580	COG1301	dicarboxylic acid transport
CG482_006585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG482_006595	COG3874	Sporulation protein YtfJ
CG482_006615	COG0028	Belongs to the TPP enzyme family
CG482_006620	COG0440	acetolactate synthase activity
CG482_006625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CG482_006630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG482_006640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG482_006645	COG0066	3-isopropylmalate dehydratase activity
CG482_006655	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CG482_006665	COG0131	Imidazoleglycerol-phosphate dehydratase
CG482_006670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG482_006680	COG0107	imidazoleglycerol-phosphate synthase activity
CG482_006685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG482_006690	COG0140	phosphoribosyl-ATP diphosphatase activity
CG482_006705	COG1183	phosphatidylcholine synthase activity
CG482_006710	COG1368	sulfuric ester hydrolase activity
CG482_006720	COG0019	diaminopimelate decarboxylase activity
CG482_006730	COG0175	sulfate reduction
CG482_006735	COG2046	Belongs to the sulfate adenylyltransferase family
CG482_006740	COG0529	Catalyzes the synthesis of activated sulfate
CG482_006745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG482_006765	COG1648	precorrin-2 dehydrogenase activity
CG482_006765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG482_006770	COG0733	neurotransmitter:sodium symporter activity
CG482_006785	COG3557	Belongs to the UPF0374 family
CG482_006790	COG1757	Na H antiporter
CG482_006805	COG4758	membrane
CG482_006810	COG4585	Histidine kinase
CG482_006815	COG2197	response regulator
CG482_006820	COG1114	Component of the transport system for branched-chain amino acids
CG482_006825	COG1525	nuclease
CG482_006825	COG4085	toxin activity
CG482_006825	COG0737	Belongs to the 5'-nucleotidase family
CG482_006855	COG3711	transcriptional antiterminator
CG482_006855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_006860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG482_006860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG482_006860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_006875	COG2801	Transposase and inactivated derivatives
CG482_006895	COG0730	response to heat
CG482_006900	COG0306	phosphate transporter
CG482_006905	COG1392	Phosphate transport regulator
CG482_006910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_006920	COG3852	Histidine kinase
CG482_006925	COG1801	Protein of unknown function DUF72
CG482_006935	COG0582	viral genome integration into host DNA
CG482_006940	COG5002	protein histidine kinase activity
CG482_006945	COG0813	purine-nucleoside phosphorylase activity
CG482_006955	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CG482_006955	COG0392	lysyltransferase activity
CG482_006975	COG1686	Belongs to the peptidase S11 family
CG482_006980	COG2715	membrane protein required for spore maturation
CG482_006985	COG0700	Nucleoside recognition
CG482_006990	COG1187	pseudouridine synthase activity
CG482_007000	COG1333	cytochrome c biogenesis protein
CG482_007005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG482_007010	COG0745	RESPONSE REGULATOR receiver
CG482_007015	COG5002	protein histidine kinase activity
CG482_007020	COG2096	Adenosyltransferase
CG482_007035	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CG482_007040	COG1141	Ferredoxin
CG482_007050	COG0514	ATP-dependent DNA helicase (RecQ)
CG482_007055	COG1266	CAAX protease self-immunity
CG482_007065	COG1408	metallophosphoesterase
CG482_007080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG482_007110	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG482_007120	COG1304	FMN binding
CG482_007145	COG1160	GTP binding
CG482_007150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG482_007170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG482_007180	COG0302	gtp cyclohydrolase
CG482_007185	COG0142	geranyltranstransferase activity
CG482_007190	COG2226	methyltransferase
CG482_007195	COG0142	geranyltranstransferase activity
CG482_007200	COG0105	UTP biosynthetic process
CG482_007205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG482_007210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CG482_007215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG482_007220	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG482_007225	COG0457	Tetratricopeptide repeat
CG482_007230	COG5582	Belongs to the UPF0302 family
CG482_007245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG482_007255	COG4347	Protein of unknown function (DUF1405)
CG482_007270	COG2738	Putative neutral zinc metallopeptidase
CG482_007280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_007285	COG1694	Mazg nucleotide pyrophosphohydrolase
CG482_007290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CG482_007295	COG1803	Methylglyoxal synthase
CG482_007300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG482_007305	COG0438	transferase activity, transferring glycosyl groups
CG482_007310	COG0617	tRNA 3'-terminal CCA addition
CG482_007325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CG482_007330	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG482_007335	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CG482_007340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG482_007340	COG1199	ATP-dependent helicase activity
CG482_007360	COG3935	DnaD domain protein
CG482_007365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG482_007375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_007375	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG482_007380	COG3331	DNA recombination
CG482_007415	COG4474	Belongs to the UPF0398 family
CG482_007420	COG3599	regulation of cell shape
CG482_007430	COG0116	Belongs to the methyltransferase superfamily
CG482_007440	COG1199	ATP-dependent helicase activity
CG482_007445	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CG482_007455	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG482_007460	COG2233	PERMEase
CG482_007465	COG2311	Membrane
CG482_007470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG482_007480	COG0456	acetyltransferase
CG482_007520	COG3766	membrane
CG482_007525	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG482_007530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_007535	COG1733	regulation of RNA biosynthetic process
CG482_007555	COG0328	RNA-DNA hybrid ribonuclease activity
CG482_007585	COG1278	Cold shock
CG482_007595	COG3162	membrane
CG482_007600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_007605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG482_007610	COG0475	glutathione-regulated potassium exporter activity
CG482_007615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG482_007620	COG2323	membrane
CG482_007625	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CG482_007650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG482_007660	COG2201	protein-glutamate methylesterase activity
CG482_007665	COG2198	Histidine kinase
CG482_007665	COG0643	Histidine kinase
CG482_007670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG482_007670	COG1776	CheC inhibitor of MCP methylation
CG482_007685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CG482_007695	COG1728	Protein conserved in bacteria
CG482_007705	COG1256	bacterial-type flagellum assembly
CG482_007710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG482_007730	COG1815	bacterial-type flagellum-dependent cell motility
CG482_007735	COG1558	bacterial-type flagellum-dependent cell motility
CG482_007740	COG1677	Flagellar hook-basal body complex protein FliE
CG482_007750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG482_007760	COG1157	protein secretion by the type III secretion system
CG482_007795	COG0835	chemotaxis
CG482_007795	COG0784	Response regulator, receiver
CG482_007805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG482_007810	COG0463	Glycosyl transferase, family 2
CG482_007810	COG0457	Tetratricopeptide repeat
CG482_007825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG482_007830	COG0741	lytic transglycosylase activity
CG482_007840	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG482_007845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG482_007845	COG1776	CheC inhibitor of MCP methylation
CG482_007855	COG1338	Plays a role in the flagellum-specific transport system
CG482_007860	COG1987	bacterial-type flagellum assembly
CG482_007870	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG482_007875	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG482_007880	COG1419	protein localization to endoplasmic reticulum
CG482_007885	COG4786	Flagellar basal body rod
CG482_007890	COG1136	(ABC) transporter
CG482_007890	COG0577	efflux transmembrane transporter activity
CG482_007920	COG1309	transcriptional regulator
CG482_007940	COG2814	Major facilitator Superfamily
CG482_007950	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_007985	COG0367	asparagine synthase
CG482_008005	COG1802	Transcriptional regulator
CG482_008020	COG1757	Na H antiporter
CG482_008025	COG0114	fumarate hydratase activity
CG482_008050	COG0534	Mate efflux family protein
CG482_008055	COG3340	Belongs to the peptidase S51 family
CG482_008060	COG2733	membrane
CG482_008070	COG1280	lysine exporter protein (LysE YggA)
CG482_008075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG482_008090	COG2502	aspartate--ammonia ligase
CG482_008095	COG1309	transcriptional regulator
CG482_008100	COG0109	protoheme IX farnesyltransferase activity
CG482_008130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG482_008140	COG4166	transmembrane transport
CG482_008145	COG2223	nitrite transmembrane transporter activity
CG482_008150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG482_008155	COG2244	polysaccharide biosynthetic process
CG482_008160	COG0733	neurotransmitter:sodium symporter activity
CG482_008165	COG5566	PFAM Mor transcription activator
CG482_008175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG482_008180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG482_008190	COG0129	dihydroxy-acid dehydratase activity
CG482_008195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG482_008200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG482_008205	COG2814	Major facilitator Superfamily
CG482_008210	COG3384	dioxygenase
CG482_008230	COG0402	S-adenosylhomocysteine deaminase activity
CG482_008235	COG4166	transmembrane transport
CG482_008245	COG1914	H( )-stimulated, divalent metal cation uptake system
CG482_008260	COG0083	homoserine kinase activity
CG482_008270	COG2390	Transcriptional regulator
CG482_008275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CG482_008300	COG1510	regulation of RNA biosynthetic process
CG482_008310	COG1454	alcohol dehydrogenase
CG482_008325	COG1012	belongs to the aldehyde dehydrogenase family
CG482_008340	COG0628	permease
CG482_008345	COG0039	L-malate dehydrogenase activity
CG482_008350	COG0523	cobalamin synthesis protein
CG482_008375	COG1686	Belongs to the peptidase S11 family
CG482_008390	COG1388	LysM domain
CG482_008390	COG0791	NLP P60 protein
CG482_008395	COG0300	oxidoreductase activity
CG482_008405	COG0460	homoserine dehydrogenase
CG482_008415	COG0083	homoserine kinase activity
CG482_008420	COG1316	TRANSCRIPTIONal
CG482_008425	COG0726	polysaccharide deacetylase
CG482_008435	COG1285	pathogenesis
CG482_008440	COG1247	-acetyltransferase
CG482_008475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CG482_008480	COG0577	efflux transmembrane transporter activity
CG482_008485	COG2409	Drug exporters of the RND superfamily
CG482_008490	COG1404	Belongs to the peptidase S8 family
CG482_008505	COG0840	transmembrane signaling receptor activity
CG482_008525	COG0783	Belongs to the Dps family
CG482_008545	COG0523	cobalamin synthesis protein
CG482_008555	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG482_008570	COG1902	pentaerythritol trinitrate reductase activity
CG482_008575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG482_008585	COG4166	transmembrane transport
CG482_008590	COG0346	lactoylglutathione lyase activity
CG482_008600	COG5337	Spore coat protein CotH
CG482_008605	COG1051	belongs to the nudix hydrolase family
CG482_008610	COG0586	Pfam SNARE associated Golgi protein
CG482_008615	COG2244	polysaccharide biosynthetic process
CG482_008625	COG0701	Predicted permease
CG482_008630	COG3689	TIGRFAM TIGR03943 family protein
CG482_008635	COG1607	acyl-coa hydrolase
CG482_008645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG482_008655	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_008665	COG2839	Protein conserved in bacteria
CG482_008670	COG1253	flavin adenine dinucleotide binding
CG482_008710	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG482_008720	COG1876	peptidase activity
CG482_008770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG482_008775	COG1819	glycosyl
CG482_008780	COG1819	glycosyl
CG482_008785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG482_008830	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG482_008870	COG3874	Sporulation protein YtfJ
CG482_008895	COG2226	methyltransferase
CG482_008920	COG0386	Belongs to the glutathione peroxidase family
CG482_008950	COG0640	Transcriptional regulator
CG482_008955	COG0798	PFAM Bile acid sodium symporter
CG482_008960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG482_009005	COG1418	mRNA catabolic process
CG482_009010	COG0488	(ABC) transporter
CG482_009020	COG0629	single-stranded DNA binding
CG482_009025	COG1413	lyase activity
CG482_009040	COG2136	Putative SAM-dependent methyltransferase
CG482_009040	COG2521	methyltransferase
CG482_009045	COG0018	arginyl-trna synthetase
CG482_009055	COG0733	neurotransmitter:sodium symporter activity
CG482_009075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG482_009080	COG0477	Major facilitator Superfamily
CG482_009095	COG1454	alcohol dehydrogenase
CG482_009110	COG0456	acetyltransferase
CG482_009115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG482_009125	COG1131	(ABC) transporter
CG482_009130	COG4473	ABC transporter
CG482_009145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG482_009150	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG482_009160	COG0768	penicillin binding
CG482_009170	COG0204	Acyl-transferase
CG482_009180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG482_009185	COG0805	protein transport
CG482_009195	COG1307	EDD domain protein, DegV family
CG482_009205	COG1999	signal sequence binding
CG482_009210	COG0071	Belongs to the small heat shock protein (HSP20) family
CG482_009215	COG0367	asparagine synthase
CG482_009230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG482_009250	COG0071	Belongs to the small heat shock protein (HSP20) family
CG482_009260	COG1737	Transcriptional regulator
CG482_009265	COG1070	Carbohydrate kinase
CG482_009275	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CG482_009330	COG1151	hydroxylamine reductase activity
CG482_009340	COG1253	flavin adenine dinucleotide binding
CG482_009345	COG5506	Protein of unknown function (DUF1694)
CG482_009365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG482_009370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CG482_009375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG482_009380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG482_009390	COG3829	transcription factor binding
CG482_009400	COG1509	lysine 2,3-aminomutase activity
CG482_009410	COG4479	Belongs to the UPF0346 family
CG482_009415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG482_009445	COG0515	serine threonine protein kinase
CG482_009445	COG1357	PFAM Pentapeptide repeats (8 copies)
CG482_009455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG482_009460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG482_009505	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CG482_009515	COG0726	polysaccharide deacetylase
CG482_009520	COG1408	metallophosphoesterase
CG482_009525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG482_009530	COG2323	membrane
CG482_009535	COG0671	phosphoesterase, PA-phosphatase related
CG482_009545	COG1280	lysine exporter protein (LysE YggA)
CG482_009550	COG3403	YqcI/YcgG family
CG482_009580	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG482_009580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_009590	COG0372	Belongs to the citrate synthase family
CG482_009595	COG2079	MmgE PrpD family protein
CG482_009600	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CG482_009605	COG1960	acyl-CoA dehydrogenase activity
CG482_009610	COG2084	Dehydrogenase
CG482_009615	COG1012	belongs to the aldehyde dehydrogenase family
CG482_009625	COG1280	lysine exporter protein (LysE YggA)
CG482_009645	COG0420	3'-5' exonuclease activity
CG482_009650	COG0419	ATPase involved in DNA repair
CG482_009655	COG3104	oligopeptide transport
CG482_009680	COG1131	(ABC) transporter
CG482_009700	COG1131	(ABC) transporter
CG482_009705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG482_009725	COG1942	4-Oxalocrotonate Tautomerase
CG482_009740	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_009745	COG1169	isochorismate synthase
CG482_009750	COG1021	2,3-dihydroxybenzoate-AMP ligase
CG482_009755	COG1535	isochorismatase
CG482_009755	COG3433	isochorismatase activity
CG482_009760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG482_009765	COG3251	PFAM MbtH domain protein
CG482_009770	COG2814	Major facilitator Superfamily
CG482_009835	COG0776	regulation of translation
CG482_009850	COG2329	Antibiotic biosynthesis monooxygenase
CG482_009890	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CG482_009900	COG0667	Aldo Keto reductase
CG482_009920	COG0010	Belongs to the arginase family
CG482_009930	COG1132	(ABC) transporter
CG482_009935	COG1132	(ABC) transporter
CG482_009965	COG1649	PFAM Uncharacterised BCR, COG1649
CG482_009980	COG2971	BadF BadG BcrA BcrD
CG482_010000	COG0588	phosphoglycerate mutase activity
CG482_010030	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG482_010040	COG1960	acyl-CoA dehydrogenase activity
CG482_010045	COG0439	Biotin carboxylase
CG482_010050	COG0511	ligase activity, forming carbon-carbon bonds
CG482_010055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG482_010060	COG1024	Enoyl-CoA hydratase
CG482_010065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG482_010070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG482_010080	COG1216	Glycosyl transferase, family 2
CG482_010085	COG0640	Transcriptional regulator
CG482_010100	COG1686	Belongs to the peptidase S11 family
CG482_010105	COG5002	protein histidine kinase activity
CG482_010135	COG0789	Transcriptional regulator
CG482_010160	COG0745	RESPONSE REGULATOR receiver
CG482_010180	COG2002	toxin-antitoxin pair type II binding
CG482_010185	COG3409	Peptidoglycan-binding domain 1 protein
CG482_010185	COG3773	Cell wall hydrolase
CG482_010200	COG0693	protein deglycase activity
CG482_010205	COG0201	protein transport
CG482_010225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG482_010230	COG0322	excinuclease ABC activity
CG482_010245	COG4667	esterase of the alpha-beta hydrolase superfamily
CG482_010285	COG2223	nitrite transmembrane transporter activity
CG482_010335	COG1216	Glycosyl transferase, family 2
CG482_010350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG482_010355	COG1279	arginine transmembrane transporter activity
CG482_010395	COG1794	racemase activity, acting on amino acids and derivatives
CG482_010405	COG2828	Protein conserved in bacteria
CG482_010410	COG5002	protein histidine kinase activity
CG482_010415	COG0561	phosphatase activity
CG482_010435	COG2124	cytochrome p450
CG482_010480	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG482_010510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG482_010515	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_010525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG482_010535	COG2959	enzyme of heme biosynthesis
CG482_010540	COG3773	Cell wall hydrolase
CG482_010540	COG3409	Peptidoglycan-binding domain 1 protein
CG482_010565	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CG482_010570	COG3844	kynureninase activity
CG482_010580	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_010590	COG4176	ABC-type proline glycine betaine transport system permease component
CG482_010595	COG4175	Glycine betaine
CG482_010595	COG0517	IMP dehydrogenase activity
CG482_010625	COG2153	protein acetylation
CG482_010650	COG0514	ATP-dependent DNA helicase (RecQ)
CG482_010670	COG4637	Psort location Cytoplasmic, score
CG482_010675	COG1227	inorganic diphosphatase activity
CG482_010685	COG3397	chitin binding
CG482_010725	COG4166	transmembrane transport
CG482_010735	COG4948	Mandelate Racemase Muconate Lactonizing
CG482_010805	COG1307	EDD domain protein, DegV family
CG482_010875	COG2261	transglycosylase associated protein
CG482_010895	COG2826	transposase and inactivated derivatives, IS30 family
CG482_010910	COG0436	Aminotransferase
CG482_010935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG482_010960	COG0628	permease
CG482_010975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG482_010980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG482_010985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG482_011000	COG2746	aminoglycoside 3-N-acetyltransferase activity
CG482_011020	COG0454	-acetyltransferase
CG482_011020	COG0456	acetyltransferase
CG482_011030	COG0726	polysaccharide deacetylase
CG482_011035	COG3037	sugar-specific permease SgaT UlaA
CG482_011045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_011050	COG1368	sulfuric ester hydrolase activity
CG482_011055	COG0488	(ABC) transporter
CG482_011060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG482_011060	COG1605	Chorismate mutase
CG482_011080	COG0346	lactoylglutathione lyase activity
CG482_011090	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG482_011095	COG1518	maintenance of DNA repeat elements
CG482_011135	COG2329	Antibiotic biosynthesis monooxygenase
CG482_011150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG482_011175	COG0494	nUDIX hydrolase
CG482_011190	COG0456	acetyltransferase
CG482_011195	COG0477	Major facilitator Superfamily
CG482_011210	COG0697	spore germination
CG482_011215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG482_011225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG482_011240	COG0730	response to heat
CG482_011250	COG0833	amino acid
CG482_011270	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CG482_011285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CG482_011290	COG1984	allophanate hydrolase subunit 2
CG482_011295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG482_011300	COG1414	Transcriptional regulator
CG482_011315	COG1960	acyl-CoA dehydrogenase activity
CG482_011345	COG0346	lactoylglutathione lyase activity
CG482_011355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG482_011360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG482_011365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG482_011370	COG0438	transferase activity, transferring glycosyl groups
CG482_011385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG482_011390	COG0438	transferase activity, transferring glycosyl groups
CG482_011395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG482_011405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG482_011425	COG4851	CamS sex pheromone cAM373 precursor
CG482_011525	COG0477	Major facilitator Superfamily
CG482_011540	COG1846	Transcriptional regulator
CG482_011545	COG2814	Major facilitator Superfamily
CG482_011555	COG2031	fatty acid transporter
CG482_011585	COG1122	ATPase activity
CG482_011590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG482_011610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG482_011625	COG1131	(ABC) transporter
CG482_011685	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CG482_011690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_011695	COG0579	oxidoreductase
CG482_011700	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CG482_011710	COG1253	flavin adenine dinucleotide binding
CG482_011715	COG0789	Transcriptional regulator
CG482_011720	COG3813	Protein conserved in bacteria
CG482_011735	COG0384	phenazine biosynthesis protein PhzF
CG482_011800	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG482_011845	COG1136	(ABC) transporter
CG482_011845	COG0577	efflux transmembrane transporter activity
CG482_011915	COG0577	efflux transmembrane transporter activity
CG482_011915	COG1136	(ABC) transporter
CG482_011970	COG2072	flavoprotein involved in K transport
CG482_011995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG482_012000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG482_012015	COG1193	negative regulation of DNA recombination
CG482_012025	COG1164	Oligoendopeptidase f
CG482_012045	COG0584	glycerophosphoryl diester phosphodiesterase
CG482_012050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG482_012080	COG3397	chitin binding
CG482_012090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG482_012095	COG0277	FAD linked oxidase domain protein
CG482_012100	COG1285	pathogenesis
CG482_012105	COG2720	vancomycin resistance protein
CG482_012140	COG4824	toxin secretion phage lysis holin
CG482_012250	COG0270	DNA (cytosine-5-)-methyltransferase activity
CG482_012295	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CG482_012315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_012315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_012385	COG1484	DNA-dependent DNA replication
CG482_012425	COG0582	viral genome integration into host DNA
CG482_012450	COG1278	Cold shock
CG482_012460	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_012465	COG0165	Argininosuccinate lyase
CG482_012480	COG3409	Peptidoglycan-binding domain 1 protein
CG482_012495	COG4145	pantothenate transmembrane transporter activity
CG482_012500	COG3924	membrane
CG482_012505	COG1012	belongs to the aldehyde dehydrogenase family
CG482_012520	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CG482_012525	COG2962	Rard protein
CG482_012560	COG2226	methyltransferase
CG482_012565	COG4166	transmembrane transport
CG482_012570	COG4166	transmembrane transport
CG482_012575	COG1301	dicarboxylic acid transport
CG482_012580	COG0673	inositol 2-dehydrogenase activity
CG482_012585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG482_012590	COG0187	DNA topoisomerase II activity
CG482_012600	COG1832	CoA-binding protein
CG482_012605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG482_012610	COG0745	RESPONSE REGULATOR receiver
CG482_012625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG482_012630	COG4841	protein insertion into membrane
CG482_012635	COG0824	Thioesterase
CG482_012665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG482_012670	COG3655	Transcriptional regulator
CG482_012690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG482_012700	COG0726	polysaccharide deacetylase
CG482_012730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG482_012735	COG0318	PFAM AMP-dependent synthetase and ligase
CG482_012765	COG0457	Tetratricopeptide repeat
CG482_012845	COG2826	transposase and inactivated derivatives, IS30 family
CG482_012860	COG0534	Mate efflux family protein
CG482_012890	COG3023	N-Acetylmuramoyl-L-alanine amidase
CG482_012900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_012910	COG5002	protein histidine kinase activity
CG482_012915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_012920	COG0010	Belongs to the arginase family
CG482_012925	COG1228	amidohydrolase
CG482_012930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CG482_012935	COG2986	histidine ammonia-lyase
CG482_012960	COG4846	Membrane protein involved in cytochrome C biogenesis
CG482_012965	COG0785	Cytochrome C biogenesis protein
CG482_012980	COG0583	DNA-binding transcription factor activity
CG482_012985	COG1380	Effector of murein hydrolase LrgA
CG482_012990	COG1346	cytolysis
CG482_012995	COG4187	Peptidase family M20/M25/M40
CG482_013005	COG0833	amino acid
CG482_013015	COG0730	response to heat
CG482_013025	COG3409	Peptidoglycan-binding domain 1 protein
CG482_013025	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG482_013040	COG1132	(ABC) transporter
CG482_013045	COG1132	(ABC) transporter
CG482_013050	COG3763	UPF0154 protein
CG482_013065	COG3639	organic phosphonate transmembrane transporter activity
CG482_013070	COG3639	organic phosphonate transmembrane transporter activity
CG482_013085	COG0737	Belongs to the 5'-nucleotidase family
CG482_013090	COG4224	UPF0291 protein
CG482_013095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG482_013100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CG482_013115	COG1695	Transcriptional regulator
CG482_013155	COG3328	transposase activity
CG482_013160	COG3328	transposase activity
CG482_013170	COG1598	PFAM Uncharacterised protein family UPF0150
CG482_013180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG482_013205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG482_013225	COG0730	response to heat
CG482_013310	COG4824	toxin secretion phage lysis holin
CG482_013390	COG3728	DNA packaging
CG482_013400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG482_013530	COG0582	viral genome integration into host DNA
CG482_013535	COG0174	glutamine synthetase
CG482_013540	COG0789	Transcriptional regulator
CG482_013545	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CG482_013550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG482_013555	COG2860	membrane
CG482_013560	COG0464	growth
CG482_013575	COG1923	regulation of RNA biosynthetic process
CG482_013580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG482_013590	COG3584	3D domain protein
CG482_013590	COG1388	LysM domain
CG482_013595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_013595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG482_013595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG482_013600	COG1105	Belongs to the carbohydrate kinase PfkB family
CG482_013605	COG1349	DNA-binding transcription factor activity
CG482_013610	COG2322	membrane
CG482_013635	COG2116	formate transmembrane transporter activity
CG482_013645	COG1937	Protein conserved in bacteria
CG482_013650	COG2819	hydrolase of the alpha beta superfamily
CG482_013655	COG1120	ATPase activity
CG482_013660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_013665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_013670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG482_013675	COG2706	6-phosphogluconolactonase activity
CG482_013680	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG482_013690	COG0346	lactoylglutathione lyase activity
CG482_013705	COG1113	amino acid transport
CG482_013730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG482_013735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG482_013745	COG4550	Control of competence regulator ComK, YlbF/YmcA
CG482_013750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG482_013755	COG1013	pyruvate-flavodoxin oxidoreductase activity
CG482_013760	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CG482_013760	COG0674	pyruvate-flavodoxin oxidoreductase activity
CG482_013770	COG2359	stage V sporulation protein S
CG482_013775	COG1692	metallophosphoesterase
CG482_013780	COG1418	mRNA catabolic process
CG482_013785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG482_013790	COG1546	Belongs to the CinA family
CG482_013790	COG1058	Belongs to the CinA family
CG482_013795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG482_013800	COG1426	Protein conserved in bacteria
CG482_013825	COG0612	Peptidase, M16
CG482_013830	COG0612	Peptidase, M16
CG482_013855	COG2188	Transcriptional regulator
CG482_013860	COG1674	ftsk spoiiie
CG482_013875	COG0740	serine-type endopeptidase activity
CG482_013900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG482_013920	COG0527	aspartate kinase activity
CG482_013925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG482_013930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG482_013935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG482_013940	COG1873	PFAM PRC-barrel domain
CG482_013945	COG0612	Peptidase, M16
CG482_013950	COG0726	polysaccharide deacetylase
CG482_013955	COG1185	polyribonucleotide nucleotidyltransferase activity
CG482_013965	COG0196	riboflavin kinase activity
CG482_013970	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG482_013975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CG482_013980	COG1550	Protein conserved in bacteria
CG482_013985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CG482_013990	COG1358	cellular component organization or biogenesis
CG482_013995	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CG482_014000	COG0195	Participates in both transcription termination and antitermination
CG482_014005	COG0779	Required for maturation of 30S ribosomal subunits
CG482_014015	COG0442	prolyl-tRNA aminoacylation
CG482_014020	COG0750	zinc metalloprotease
CG482_014030	COG4589	Belongs to the CDS family
CG482_014040	COG0233	cytoplasmic translational termination
CG482_014045	COG0528	UMP kinase activity
CG482_014050	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG482_014055	COG0052	Belongs to the universal ribosomal protein uS2 family
CG482_014060	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CG482_014065	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CG482_014070	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CG482_014075	COG4974	Belongs to the 'phage' integrase family
CG482_014080	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CG482_014085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG482_014090	COG0758	DNA mediated transformation
CG482_014095	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CG482_014100	COG0045	succinate-CoA ligase (ADP-forming) activity
CG482_014105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG482_014120	COG0335	large ribosomal subunit rRNA binding
CG482_014130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CG482_014135	COG1837	Belongs to the UPF0109 family
CG482_014140	COG0228	four-way junction DNA binding
CG482_014145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG482_014150	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CG482_014155	COG0552	protein localization to endoplasmic reticulum
CG482_014160	COG1196	nuclear chromosome segregation
CG482_014165	COG0571	ribonuclease III activity
CG482_014175	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_014180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CG482_014185	COG0416	fatty acid biosynthetic process
CG482_014190	COG1349	DNA-binding transcription factor activity
CG482_014190	COG2050	protein possibly involved in aromatic compounds catabolism
CG482_014195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG482_014200	COG1461	Dihydroxyacetone kinase
CG482_014205	COG1302	Protein conserved in bacteria
CG482_014210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CG482_014220	COG1564	THIamine pyrophosphokinase
CG482_014225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CG482_014230	COG1162	GTPase activity
CG482_014235	COG2815	serine threonine protein kinase
CG482_014235	COG0515	serine threonine protein kinase
CG482_014240	COG0631	protein serine/threonine phosphatase activity
CG482_014245	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG482_014250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG482_014250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG482_014255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG482_014260	COG0242	peptide deformylase activity
CG482_014265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG482_014270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG482_014275	COG1758	RNA polymerase activity
CG482_014280	COG0194	GDP metabolic process
CG482_014290	COG1561	YicC-like family, N-terminal region
CG482_014295	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG482_014320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CG482_014325	COG0284	orotidine-5'-phosphate decarboxylase activity
CG482_014330	COG0167	dihydroorotate dehydrogenase activity
CG482_014335	COG0543	2 iron, 2 sulfur cluster binding
CG482_014340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CG482_014350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CG482_014355	COG0540	Belongs to the ATCase OTCase family
CG482_014365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CG482_014375	COG0564	pseudouridine synthase activity
CG482_014380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG482_014390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CG482_014395	COG3599	regulation of cell shape
CG482_014400	COG2302	S4 RNA-binding domain
CG482_014405	COG0762	integral membrane protein
CG482_014410	COG1799	cell septum assembly
CG482_014415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CG482_014425	COG1873	PFAM PRC-barrel domain
CG482_014430	COG1191	sigma factor activity
CG482_014435	COG1191	sigma factor activity
CG482_014445	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG482_014450	COG0849	cell division
CG482_014455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG482_014465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG482_014470	COG0772	Belongs to the SEDS family
CG482_014475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG482_014480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG482_014485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG482_014490	COG0768	penicillin binding
CG482_014500	COG4839	cell division protein FtsL
CG482_014505	COG0275	rRNA processing
CG482_014510	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CG482_014515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CG482_014535	COG1399	metal-binding, possibly nucleic acid-binding protein
CG482_014645	COG4626	Terminase
CG482_014645	COG1802	Transcriptional regulator
CG482_014730	COG0756	dUTP diphosphatase activity
CG482_014760	COG3723	Recombinational DNA repair protein, rece pathway
CG482_014770	COG5377	YqaJ viral recombinase family
CG482_014815	COG0582	viral genome integration into host DNA
CG482_014820	COG1323	Belongs to the UPF0348 family
CG482_014825	COG3480	Lon protease (S16) C-terminal proteolytic domain
CG482_014830	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG482_014835	COG3314	Sporulation integral membrane protein YlbJ
CG482_014840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG482_014845	COG0742	ribosomal rna small subunit methyltransferase
CG482_014855	COG4471	UPF0298 protein
CG482_014860	COG3679	Belongs to the UPF0342 family
CG482_014865	COG0406	alpha-ribazole phosphatase activity
CG482_014880	COG2340	Cysteine-rich secretory protein family
CG482_014890	COG3336	cytochrome c oxidase
CG482_014915	COG0109	protoheme IX farnesyltransferase activity
CG482_014920	COG1612	heme a metabolic process
CG482_014925	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CG482_014935	COG0772	Belongs to the SEDS family
CG482_014940	COG4838	Belongs to the UPF0358 family
CG482_014945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CG482_014950	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CG482_014960	COG4896	Protein conserved in bacteria
CG482_014985	COG0483	inositol monophosphate 1-phosphatase activity
CG482_014995	COG4493	Belongs to the UPF0637 family
CG482_015000	COG4476	Belongs to the UPF0223 family
CG482_015005	COG1982	Orn Lys Arg decarboxylase major
CG482_015045	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG482_015055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG482_015070	COG0561	phosphatase activity
CG482_015085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG482_015090	COG0569	domain protein
CG482_015100	COG1473	amidohydrolase
CG482_015105	COG2171	N-acyltransferase activity
CG482_015110	COG0583	DNA-binding transcription factor activity
CG482_015115	COG0517	IMP dehydrogenase activity
CG482_015125	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CG482_015135	COG4703	Protein of unknown function (DUF1797)
CG482_015150	COG2200	EAL domain
CG482_015155	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_015160	COG1408	metallophosphoesterase
CG482_015170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CG482_015190	COG0726	polysaccharide deacetylase
CG482_015210	COG2814	Major facilitator Superfamily
CG482_015215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG482_015225	COG3209	COG3209 Rhs family protein
CG482_015235	COG2205	protein histidine kinase activity
CG482_015245	COG0436	Aminotransferase
CG482_015250	COG1609	Transcriptional regulator
CG482_015285	COG0183	Belongs to the thiolase family
CG482_015315	COG1695	Transcriptional regulator
CG482_015320	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_015330	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CG482_015335	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CG482_015340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG482_015345	COG0436	Aminotransferase
CG482_015350	COG1850	ribulose-bisphosphate carboxylase activity
CG482_015355	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CG482_015360	COG0235	Class ii aldolase
CG482_015365	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CG482_015380	COG2084	Dehydrogenase
CG482_015395	COG0778	Nitroreductase
CG482_015420	COG2190	(PTS) system
CG482_015420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_015420	COG1263	PTS System
CG482_015425	COG3711	transcriptional antiterminator
CG482_015440	COG0363	glucosamine-6-phosphate deaminase activity
CG482_015455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG482_015460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG482_015470	COG1547	Domain of unknown function (DUF309)
CG482_015480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CG482_015485	COG4086	secreted protein
CG482_015490	COG0561	phosphatase activity
CG482_015495	COG0697	spore germination
CG482_015510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG482_015535	COG0733	neurotransmitter:sodium symporter activity
CG482_015545	COG2172	sigma factor antagonist activity
CG482_015555	COG1686	Belongs to the peptidase S11 family
CG482_015565	COG1725	Transcriptional regulator
CG482_015570	COG1131	(ABC) transporter
CG482_015590	COG1846	Transcriptional regulator
CG482_015605	COG0598	Magnesium transport protein CorA
CG482_015630	COG4974	Belongs to the 'phage' integrase family
CG482_015640	COG0735	belongs to the Fur family
CG482_015645	COG1300	Membrane
CG482_015665	COG0667	Aldo Keto reductase
CG482_015670	COG0656	L-ascorbic acid biosynthetic process
CG482_015675	COG0456	acetyltransferase
CG482_015675	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CG482_015685	COG4085	toxin activity
CG482_015685	COG1525	nuclease
CG482_015685	COG0737	Belongs to the 5'-nucleotidase family
CG482_015695	COG0596	Alpha beta hydrolase
CG482_015700	COG2056	Na+-H+ antiporter family
CG482_015705	COG1609	Transcriptional regulator
CG482_015710	COG0456	acetyltransferase
CG482_015715	COG1073	alpha beta
CG482_015730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG482_015730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG482_015735	COG0307	riboflavin synthase, alpha
CG482_015740	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG482_015740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG482_015755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG482_015760	COG4106	trans-aconitate 2-methyltransferase activity
CG482_015765	COG0596	Alpha beta hydrolase
CG482_015770	COG0156	8-amino-7-oxononanoate synthase activity
CG482_015780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG482_015795	COG0737	Belongs to the 5'-nucleotidase family
CG482_015820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG482_015830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG482_015840	COG0300	oxidoreductase activity
CG482_015845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG482_015850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG482_015855	COG1760	l-serine dehydratase
CG482_015860	COG1760	l-serine dehydratase
CG482_015870	COG1234	tRNA 3'-trailer cleavage
CG482_015890	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG482_015895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG482_015910	COG1376	ErfK ybiS ycfS ynhG family protein
CG482_015915	COG4129	membrane
CG482_015920	COG1126	abc transporter atp-binding protein
CG482_015925	COG0765	amino acid transport
CG482_015930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG482_015945	COG2816	NAD+ diphosphatase activity
CG482_015950	COG0772	Belongs to the SEDS family
CG482_015960	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG482_015965	COG0022	dehydrogenase e1 component
CG482_015970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG482_015975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG482_015980	COG3426	butyrate kinase activity
CG482_015985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG482_015990	COG0280	phosphate acetyltransferase
CG482_016000	COG3290	protein histidine kinase activity
CG482_016000	COG3829	transcription factor binding
CG482_016010	COG0584	glycerophosphoryl diester phosphodiesterase
CG482_016015	COG3093	addiction module antidote protein HigA
CG482_016020	COG0745	RESPONSE REGULATOR receiver
CG482_016030	COG0750	zinc metalloprotease
CG482_016035	COG0497	DNA recombination
CG482_016045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CG482_016050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG482_016060	COG1722	exodeoxyribonuclease VII activity
CG482_016065	COG1570	exodeoxyribonuclease VII activity
CG482_016070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG482_016075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG482_016080	COG1302	Protein conserved in bacteria
CG482_016085	COG0439	Biotin carboxylase
CG482_016090	COG0511	ligase activity, forming carbon-carbon bonds
CG482_016135	COG3854	ATPases associated with a variety of cellular activities
CG482_016155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG482_016160	COG0006	proline dipeptidase activity
CG482_016165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG482_016175	COG3872	metal-dependent enzyme
CG482_016185	COG1321	iron dependent repressor
CG482_016200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG482_016210	COG1609	Transcriptional regulator
CG482_016220	COG2076	Multidrug Resistance protein
CG482_016225	COG2076	Multidrug Resistance protein
CG482_016250	COG1131	(ABC) transporter
CG482_016255	COG1725	Transcriptional regulator
CG482_016270	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG482_016275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG482_016280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG482_016315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG482_016340	COG1459	type II secretion system
CG482_016365	COG4824	toxin secretion phage lysis holin
CG482_016445	COG3728	DNA packaging
CG482_016455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG482_016565	COG1396	sequence-specific DNA binding
CG482_016580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG482_016615	COG1078	dGTPase activity
CG482_016630	COG1410	methionine synthase
CG482_016630	COG0646	methionine synthase
CG482_016635	COG0646	methionine synthase
CG482_016635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CG482_016640	COG0626	cystathionine gamma-synthase activity
CG482_016645	COG0626	cystathionine gamma-synthase activity
CG482_016665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG482_016675	COG1940	carbohydrate kinase activity
CG482_016680	COG4483	Protein conserved in bacteria
CG482_016685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CG482_016690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG482_016700	COG0704	Plays a role in the regulation of phosphate uptake
CG482_016705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CG482_016710	COG0581	inorganic phosphate transmembrane transporter activity
CG482_016715	COG0573	inorganic phosphate transmembrane transporter activity
CG482_016720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG482_016730	COG0477	Major facilitator Superfamily
CG482_016735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG482_016755	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG482_016760	COG0735	belongs to the Fur family
CG482_016765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG482_016770	COG1121	(ABC) transporter
CG482_016775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_016785	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CG482_016800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CG482_016805	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CG482_016810	COG2384	SAM-dependent methyltransferase
CG482_016820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG482_016825	COG0358	DNA primase activity
CG482_016830	COG1671	Belongs to the UPF0178 family
CG482_016835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CG482_016840	COG0517	IMP dehydrogenase activity
CG482_016845	COG1381	Involved in DNA repair and RecF pathway recombination
CG482_016855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG482_016865	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG482_016870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CG482_016875	COG1480	7TM receptor with intracellular HD hydrolase
CG482_016880	COG1702	phosphate starvation-inducible protein PhoH
CG482_016895	COG1610	YqeY-like protein
CG482_016900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG482_016905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG482_016910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG482_016915	COG2264	protein methyltransferase activity
CG482_016920	COG0484	heat shock protein binding
CG482_016925	COG0443	Heat shock 70 kDa protein
CG482_016930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG482_016940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG482_016945	COG1733	regulation of RNA biosynthetic process
CG482_016950	COG0693	protein deglycase activity
CG482_016955	COG0481	GTPase activity
CG482_016965	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CG482_016970	COG0268	Binds directly to 16S ribosomal RNA
CG482_016975	COG1466	dna polymerase III delta subunit
CG482_016985	COG2333	competence protein COMEC
CG482_016985	COG0658	competence protein
CG482_016990	COG2131	deaminase
CG482_016995	COG1555	photosystem II stabilization
CG482_016995	COG1596	polysaccharide export
CG482_017000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG482_017005	COG2226	methyltransferase
CG482_017010	COG0799	negative regulation of ribosome biogenesis
CG482_017015	COG1713	HD superfamily hydrolase involved in NAD metabolism
CG482_017020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG482_017025	COG1534	Rna-binding protein
CG482_017030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG482_017035	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CG482_017040	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CG482_017050	COG0688	phosphatidylethanolamine metabolic process
CG482_017055	COG1191	sigma factor activity
CG482_017065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG482_017070	COG2357	RelA SpoT domain protein
CG482_017075	COG1785	Belongs to the alkaline phosphatase family
CG482_017080	COG0456	acetyltransferase
CG482_017085	COG2267	carboxylic ester hydrolase activity
CG482_017110	COG3186	Phenylalanine-4-hydroxylase
CG482_017115	COG2154	pterin-4-alpha-carbinolamine dehydratase
CG482_017120	COG2514	catechol 2,3-dioxygenase activity
CG482_017125	COG2259	Doxx family
CG482_017145	COG1609	Transcriptional regulator
CG482_017155	COG0626	cystathionine gamma-synthase activity
CG482_017160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG482_017165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CG482_017170	COG2226	methyltransferase
CG482_017190	COG0768	penicillin binding
CG482_017200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG482_017205	COG0572	uridine kinase
CG482_017225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG482_017235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG482_017240	COG4472	Bacterial protein of unknown function (DUF965)
CG482_017245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG482_017250	COG0628	permease
CG482_017270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CG482_017280	COG0482	sulfurtransferase activity
CG482_017285	COG1104	cysteine desulfurase activity
CG482_017290	COG1959	2 iron, 2 sulfur cluster binding
CG482_017295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG482_017315	COG2207	Transcriptional regulator
CG482_017325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CG482_017330	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG482_017335	COG0124	histidyl-tRNA synthetase
CG482_017355	COG1490	D-aminoacyl-tRNA deacylase activity
CG482_017360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG482_017365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG482_017370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG482_017370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CG482_017375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG482_017380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG482_017380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG482_017390	COG2244	polysaccharide biosynthetic process
CG482_017415	COG1862	Preprotein translocase
CG482_017420	COG0343	queuine tRNA-ribosyltransferase activity
CG482_017425	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG482_017435	COG2255	four-way junction helicase activity
CG482_017440	COG0632	four-way junction helicase activity
CG482_017445	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CG482_017465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CG482_017470	COG0157	Belongs to the NadC ModD family
CG482_017475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CG482_017480	COG1104	cysteine desulfurase activity
CG482_017485	COG1827	regulation of RNA biosynthetic process
CG482_017490	COG2258	MOSC domain
CG482_017495	COG0077	Prephenate dehydratase
CG482_017500	COG0577	efflux transmembrane transporter activity
CG482_017505	COG0577	efflux transmembrane transporter activity
CG482_017510	COG1136	(ABC) transporter
CG482_017515	COG5002	protein histidine kinase activity
CG482_017520	COG0745	RESPONSE REGULATOR receiver
CG482_017530	COG3290	protein histidine kinase activity
CG482_017535	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG482_017540	COG2868	ribosomal protein
CG482_017550	COG1530	ribonuclease E activity
CG482_017555	COG1994	Peptidase M50
CG482_017560	COG0739	heme binding
CG482_017565	COG2894	cell division
CG482_017570	COG0850	regulation of cytokinetic process
CG482_017580	COG1792	Involved in formation and maintenance of cell shape
CG482_017585	COG1077	Cell shape determining protein MreB Mrl
CG482_017605	COG0424	maF-like protein
CG482_017615	COG0285	dihydrofolate synthase activity
CG482_017640	COG1388	LysM domain
CG482_017640	COG1388	LysM domain
CG482_017645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG482_017650	COG0113	porphobilinogen synthase activity
CG482_017655	COG1587	Uroporphyrinogen-III synthase
CG482_017660	COG0181	hydroxymethylbilane synthase activity
CG482_017665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG482_017670	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CG482_017675	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG482_017685	COG1067	ATP-dependent peptidase activity
CG482_017685	COG0470	DNA polymerase III
CG482_017690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CG482_017695	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_017720	COG3321	synthase
CG482_017720	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_017720	COG4221	oxidoreductase activity
CG482_017720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG482_017735	COG2409	Drug exporters of the RND superfamily
CG482_017735	COG1033	growth of symbiont in host cell
CG482_017745	COG1309	transcriptional regulator
CG482_017765	COG0622	Phosphoesterase
CG482_017775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG482_017780	COG5401	PFAM Sporulation and spore germination
CG482_017790	COG2197	response regulator
CG482_017830	COG2197	response regulator
CG482_017840	COG1959	2 iron, 2 sulfur cluster binding
CG482_017845	COG1668	transmembrane transport
CG482_017850	COG4152	abc transporter atp-binding protein
CG482_017855	COG1360	Flagellar Motor Protein
CG482_017860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG482_017870	COG1876	peptidase activity
CG482_017880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CG482_017885	COG1053	succinate dehydrogenase
CG482_017890	COG2009	succinate dehydrogenase
CG482_017895	COG1719	4-vinyl reductase, 4VR
CG482_017910	COG3118	belongs to the thioredoxin family
CG482_017915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CG482_017920	COG2086	electron transfer activity
CG482_017925	COG1024	Enoyl-CoA hydratase
CG482_017930	COG1309	transcriptional regulator
CG482_017935	COG0318	PFAM AMP-dependent synthetase and ligase
CG482_017945	COG2318	DinB family
CG482_017965	COG1131	(ABC) transporter
CG482_017970	COG2205	protein histidine kinase activity
CG482_017975	COG0745	RESPONSE REGULATOR receiver
CG482_017985	COG4895	conserved protein (DUF2196)
CG482_017990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CG482_017995	COG1114	Component of the transport system for branched-chain amino acids
CG482_018000	COG1187	pseudouridine synthase activity
CG482_018010	COG1193	negative regulation of DNA recombination
CG482_018015	COG1796	DNA polymerase
CG482_018015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CG482_018020	COG1286	toxin biosynthetic process
CG482_018025	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CG482_018050	COG0017	Asparaginyl-tRNA synthetase
CG482_018055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG482_018055	COG0072	phenylalanine-tRNA ligase activity
CG482_018060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CG482_018065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG482_018075	COG1418	mRNA catabolic process
CG482_018090	COG2814	Major facilitator Superfamily
CG482_018095	COG1566	PFAM secretion protein HlyD family protein
CG482_018100	COG1309	transcriptional regulator
CG482_018105	COG1363	Peptidase, m42
CG482_018115	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CG482_018120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CG482_018125	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CG482_018130	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG482_018140	COG1484	DNA-dependent DNA replication
CG482_018145	COG3611	Membrane attachment protein
CG482_018150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG482_018155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CG482_018165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG482_018175	COG1971	Probably functions as a manganese efflux pump
CG482_018185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_018185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_018190	COG5002	protein histidine kinase activity
CG482_018195	COG0745	RESPONSE REGULATOR receiver
CG482_018205	COG0039	L-malate dehydrogenase activity
CG482_018210	COG0538	isocitrate dehydrogenase activity
CG482_018215	COG0372	Belongs to the citrate synthase family
CG482_018220	COG2707	UPF0756 membrane protein
CG482_018225	COG0628	permease
CG482_018230	COG3030	protein affecting phage T7 exclusion by the F plasmid
CG482_018240	COG0205	6-phosphofructokinase activity
CG482_018245	COG0825	malonyl-CoA metabolic process
CG482_018250	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CG482_018255	COG1725	Transcriptional regulator
CG482_018260	COG0281	malic enzyme
CG482_018265	COG0587	DNA-directed DNA polymerase activity
CG482_018280	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CG482_018290	COG4109	DRTGG domain
CG482_018295	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CG482_018300	COG0006	proline dipeptidase activity
CG482_018325	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_018330	COG0589	response to stress
CG482_018355	COG0165	Argininosuccinate lyase
CG482_018360	COG0137	argininosuccinate synthase activity
CG482_018370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_018380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CG482_018385	COG0827	DNA restriction-modification system
CG482_018390	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CG482_018395	COG3874	Sporulation protein YtfJ
CG482_018405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CG482_018410	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CG482_018415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG482_018425	COG0301	tRNA thio-modification
CG482_018430	COG1104	cysteine desulfurase activity
CG482_018435	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CG482_018445	COG0697	spore germination
CG482_018450	COG1309	transcriptional regulator
CG482_018455	COG1956	GAF domain-containing protein
CG482_018460	COG0626	cystathionine gamma-synthase activity
CG482_018470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG482_018490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CG482_018500	COG1595	DNA-templated transcription, initiation
CG482_018515	COG0454	-acetyltransferase
CG482_018520	COG0517	IMP dehydrogenase activity
CG482_018525	COG0123	including yeast histone deacetylase and acetoin utilization protein
CG482_018530	COG1970	mechanosensitive ion channel activity
CG482_018540	COG1609	Transcriptional regulator
CG482_018550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG482_018550	COG1605	Chorismate mutase
CG482_018555	COG3118	belongs to the thioredoxin family
CG482_018565	COG2309	aminopeptidase activity
CG482_018580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG482_018600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG482_018605	COG4848	Belongs to the UPF0354 family
CG482_018610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG482_018615	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CG482_018625	COG0675	Transposase, IS605 OrfB family
CG482_018635	COG1363	Peptidase, m42
CG482_018645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG482_018650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG482_018660	COG0510	thiamine kinase activity
CG482_018665	COG1523	belongs to the glycosyl hydrolase 13 family
CG482_018675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG482_018680	COG1349	DNA-binding transcription factor activity
CG482_018685	COG1187	pseudouridine synthase activity
CG482_018690	COG2244	polysaccharide biosynthetic process
CG482_018695	COG2081	HI0933 family
CG482_018700	COG2814	Major facilitator Superfamily
CG482_018710	COG3832	glyoxalase III activity
CG482_018730	COG0463	Glycosyl transferase, family 2
CG482_018790	COG1329	Transcriptional regulator
CG482_018800	COG2223	nitrite transmembrane transporter activity
CG482_018810	COG0314	molybdopterin synthase activity
CG482_018815	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG482_018820	COG0303	'Molybdopterin
CG482_018825	COG0315	cyclic pyranopterin monophosphate synthase activity
CG482_018830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG482_018835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG482_018840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG482_018845	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CG482_018850	COG1140	nitrate reductase beta subunit
CG482_018855	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CG482_018860	COG2181	nitrate reductase activity
CG482_018875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG482_018885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG482_018920	COG0495	leucyl-tRNA aminoacylation
CG482_018925	COG2814	Major facilitator Superfamily
CG482_018935	COG1136	(ABC) transporter
CG482_018940	COG0346	lactoylglutathione lyase activity
CG482_018955	COG1242	4 iron, 4 sulfur cluster binding
CG482_018960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CG482_018965	COG1121	(ABC) transporter
CG482_018975	COG1794	racemase activity, acting on amino acids and derivatives
CG482_018985	COG2378	regulation of single-species biofilm formation
CG482_019010	COG0746	molybdenum cofactor guanylyltransferase activity
CG482_019035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG482_019045	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CG482_019090	COG3409	Peptidoglycan-binding domain 1 protein
CG482_019090	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG482_019100	COG1368	sulfuric ester hydrolase activity
CG482_019115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG482_019120	COG1116	anion transmembrane transporter activity
CG482_019125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG482_019140	COG0494	nUDIX hydrolase
CG482_019150	COG1854	S-ribosylhomocysteine lyase activity
CG482_019155	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG482_019160	COG0288	reversible hydration of carbon dioxide
CG482_019165	COG1271	oxidase subunit
CG482_019170	COG1294	oxidase, subunit
CG482_019200	COG1842	Phage shock protein A
CG482_019245	COG1597	lipid kinase activity
CG482_019250	COG0586	Pfam SNARE associated Golgi protein
CG482_019255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG482_019260	COG1136	(ABC) transporter
CG482_019270	COG0745	RESPONSE REGULATOR receiver
CG482_019275	COG2205	protein histidine kinase activity
CG482_019280	COG0577	efflux transmembrane transporter activity
CG482_019285	COG1136	(ABC) transporter
CG482_019305	COG4948	Mandelate Racemase Muconate Lactonizing
CG482_019310	COG0318	PFAM AMP-dependent synthetase and ligase
CG482_019315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG482_019320	COG0596	Alpha beta hydrolase
CG482_019325	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CG482_019330	COG1169	isochorismate synthase
CG482_019335	COG1575	Belongs to the MenA family. Type 1 subfamily
CG482_019340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CG482_019345	COG1278	Cold shock
CG482_019365	COG0058	SHG alpha-glucan phosphorylase activity
CG482_019370	COG0297	glycogen (starch) synthase activity
CG482_019375	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG482_019380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG482_019385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG482_019390	COG0039	L-malate dehydrogenase activity
CG482_019485	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_019520	COG1285	pathogenesis
CG482_019525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG482_019535	COG0166	Belongs to the GPI family
CG482_019545	COG2155	Conserved Protein
CG482_019550	COG1098	S1 RNA binding domain
CG482_019555	COG0436	Aminotransferase
CG482_019560	COG1522	sequence-specific DNA binding
CG482_019565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG482_019570	COG2267	carboxylic ester hydrolase activity
CG482_019580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CG482_019585	COG2032	superoxide dismutase activity
CG482_019595	COG5018	Exonuclease
CG482_019600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG482_019605	COG0423	glycine-tRNA ligase activity
CG482_019620	COG2050	protein possibly involved in aromatic compounds catabolism
CG482_019630	COG1268	BioY protein
CG482_019635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG482_019640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG482_019650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG482_019660	COG3584	3D domain protein
CG482_019680	COG1252	NADH dehydrogenase
CG482_019685	COG0492	ferredoxin-NADP+ reductase activity
CG482_019700	COG1683	Conserved Protein
CG482_019710	COG0316	Belongs to the HesB IscA family
CG482_019715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CG482_019720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_019730	COG1252	NADH dehydrogenase
CG482_019735	COG2824	Alkylphosphonate utilization operon protein PhnA
CG482_019745	COG3655	Transcriptional regulator
CG482_019760	COG4837	Protein of unknown function (DUF1462)
CG482_019765	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CG482_019770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG482_019775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CG482_019780	COG0647	UMP catabolic process
CG482_019790	COG2445	Protein of unknown function DUF86
CG482_019795	COG1494	fructose-1,6-bisphosphatase
CG482_019805	COG4470	Protein conserved in bacteria
CG482_019815	COG0789	Transcriptional regulator
CG482_019820	COG4377	Putative membrane peptidase family (DUF2324)
CG482_019835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CG482_019840	COG0739	heme binding
CG482_019850	COG3377	Domain of unknown function (DUF1805)
CG482_019855	COG0737	Belongs to the 5'-nucleotidase family
CG482_019875	COG0719	Fe-S assembly protein
CG482_019880	COG0822	iron-sulfur transferase activity
CG482_019885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG482_019890	COG0719	Fe-S assembly protein
CG482_019895	COG0396	ATPase activity
CG482_019900	COG1464	Belongs to the NlpA lipoprotein family
CG482_019905	COG2011	ABC-type metal ion transport system permease component
CG482_019920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG482_019925	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CG482_019930	COG0509	glycine decarboxylation via glycine cleavage system
CG482_019935	COG1393	Belongs to the ArsC family
CG482_019980	COG1960	acyl-CoA dehydrogenase activity
CG482_019985	COG0183	Belongs to the thiolase family
CG482_019990	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG482_019990	COG1024	Enoyl-CoA hydratase
CG482_020000	COG1686	Belongs to the peptidase S11 family
CG482_020025	COG0011	TIGRFAM Protein of
CG482_020030	COG0840	transmembrane signaling receptor activity
CG482_020050	COG0531	amino acid
CG482_020055	COG0706	membrane insertase activity
CG482_020065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_020075	COG5002	protein histidine kinase activity
CG482_020080	COG0745	RESPONSE REGULATOR receiver
CG482_020095	COG1131	(ABC) transporter
CG482_020105	COG0586	Pfam SNARE associated Golgi protein
CG482_020115	COG1376	ErfK ybiS ycfS ynhG family protein
CG482_020125	COG5002	protein histidine kinase activity
CG482_020130	COG0840	transmembrane signaling receptor activity
CG482_020135	COG0840	transmembrane signaling receptor activity
CG482_020140	COG2151	metal-sulfur cluster biosynthetic enzyme
CG482_020145	COG3227	Zinc metalloprotease (Elastase)
CG482_020150	COG1741	Belongs to the pirin family
CG482_020165	COG0783	Belongs to the Dps family
CG482_020170	COG1611	Belongs to the LOG family
CG482_020195	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG482_020200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG482_020205	COG1121	(ABC) transporter
CG482_020235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_020240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_020245	COG1115	amino acid carrier protein
CG482_020250	COG2910	NAD(P)H-binding
CG482_020265	COG1252	NADH dehydrogenase
CG482_020280	COG1595	DNA-templated transcription, initiation
CG482_020290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CG482_020305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG482_020310	COG1917	Cupin 2, conserved barrel domain protein
CG482_020310	COG4977	sequence-specific DNA binding
CG482_020320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CG482_020340	COG0697	spore germination
CG482_020355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CG482_020360	COG0557	exoribonuclease II activity
CG482_020365	COG1647	Serine aminopeptidase, S33
CG482_020370	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG482_020375	COG1346	cytolysis
CG482_020385	COG0148	phosphopyruvate hydratase activity
CG482_020390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CG482_020395	COG0149	triose-phosphate isomerase activity
CG482_020400	COG0126	phosphoglycerate kinase activity
CG482_020405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG482_020420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CG482_020445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG482_020460	COG2323	membrane
CG482_020470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_020475	COG1481	regulation of sporulation
CG482_020480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CG482_020485	COG1660	Displays ATPase and GTPase activities
CG482_020490	COG1051	belongs to the nudix hydrolase family
CG482_020500	COG0492	ferredoxin-NADP+ reductase activity
CG482_020505	COG0457	Tetratricopeptide repeat
CG482_020510	COG0110	maltose O-acetyltransferase activity
CG482_020520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG482_020525	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CG482_020530	COG1950	PFAM Membrane protein of
CG482_020540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG482_020555	COG0789	Transcriptional regulator
CG482_020575	COG0583	DNA-binding transcription factor activity
CG482_020590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG482_020595	COG0793	Belongs to the peptidase S41A family
CG482_020595	COG3409	Peptidoglycan-binding domain 1 protein
CG482_020600	COG2177	Part of the ABC transporter FtsEX involved in
CG482_020605	COG2884	Cell division ATP-binding protein ftsE
CG482_020640	COG1278	Cold shock
CG482_020645	COG1040	competence protein
CG482_020650	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CG482_020655	COG0791	NLP P60 protein
CG482_020655	COG1388	LysM domain
CG482_020660	COG1733	regulation of RNA biosynthetic process
CG482_020665	COG1307	EDD domain protein, DegV family
CG482_020670	COG1739	Uncharacterized protein family UPF0029
CG482_020675	COG1316	TRANSCRIPTIONal
CG482_020695	COG0457	Tetratricopeptide repeat
CG482_020725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CG482_020735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG482_020745	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CG482_020745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CG482_020760	COG1486	melibiose metabolic process
CG482_020765	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG482_020780	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG482_020785	COG1301	dicarboxylic acid transport
CG482_020790	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CG482_020800	COG1271	oxidase subunit
CG482_020805	COG1294	oxidase, subunit
CG482_020810	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CG482_020815	COG1620	l-lactate permease
CG482_020820	COG2389	metal-binding protein
CG482_020830	COG1368	sulfuric ester hydrolase activity
CG482_020840	COG0791	NLP P60 protein
CG482_020840	COG1388	LysM domain
CG482_020845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_020855	COG1215	transferase activity, transferring glycosyl groups
CG482_020865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG482_020870	COG3584	3D domain protein
CG482_020870	COG1388	LysM domain
CG482_020885	COG4715	Zinc finger, swim domain protein
CG482_020890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG482_020930	COG0577	efflux transmembrane transporter activity
CG482_020935	COG1136	(ABC) transporter
CG482_020970	COG5002	protein histidine kinase activity
CG482_020970	COG3850	Histidine kinase
CG482_020975	COG0745	RESPONSE REGULATOR receiver
CG482_020980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG482_020990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG482_020995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG482_021000	COG1134	teichoic acid transport
CG482_021005	COG1682	transport, permease protein
CG482_021010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG482_021020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG482_021025	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG482_021030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CG482_021040	COG1609	Transcriptional regulator
CG482_021050	COG0739	heme binding
CG482_021065	COG3279	Response regulator of the LytR AlgR family
CG482_021070	COG2385	sporulation resulting in formation of a cellular spore
CG482_021085	COG4836	Membrane
CG482_021090	COG1007	ATP synthesis coupled electron transport
CG482_021095	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG482_021100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG482_021105	COG0713	ATP synthesis coupled electron transport
CG482_021110	COG0839	Belongs to the complex I subunit 6 family
CG482_021125	COG0649	NAD binding
CG482_021130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG482_021135	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG482_021140	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG482_021145	COG5001	Diguanylate cyclase
CG482_021145	COG3300	MHYT domain
CG482_021150	COG3300	MHYT domain
CG482_021150	COG5001	Diguanylate cyclase
CG482_021165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG482_021170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG482_021175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG482_021185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG482_021190	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG482_021195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG482_021200	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG482_021225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG482_021230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG482_021240	COG0698	ribose 5-phosphate isomerase
CG482_021260	COG2190	(PTS) system
CG482_021265	COG2259	Doxx family
CG482_021270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG482_021285	COG0009	L-threonylcarbamoyladenylate synthase
CG482_021300	COG2890	protein-(glutamine-N5) methyltransferase activity
CG482_021305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG482_021310	COG1435	thymidine kinase activity
CG482_021320	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG482_021325	COG1494	fructose-1,6-bisphosphatase
CG482_021345	COG4821	SIS domain
CG482_021350	COG0504	CTP synthase activity
CG482_021365	COG1960	acyl-CoA dehydrogenase activity
CG482_021370	COG1960	acyl-CoA dehydrogenase activity
CG482_021375	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG482_021380	COG0183	Belongs to the thiolase family
CG482_021385	COG2181	nitrate reductase activity
CG482_021385	COG0247	lactate metabolic process
CG482_021390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG482_021405	COG2197	response regulator
CG482_021410	COG4585	Histidine kinase
CG482_021415	COG0842	Transport permease protein
CG482_021420	COG1131	(ABC) transporter
CG482_021425	COG0024	Methionine aminopeptidase
CG482_021430	COG2234	aminopeptidase activity
CG482_021445	COG4506	Protein conserved in bacteria
CG482_021450	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG482_021470	COG0010	Belongs to the arginase family
CG482_021475	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CG482_021480	COG2814	Major facilitator Superfamily
CG482_021485	COG0789	Transcriptional regulator
CG482_021490	COG0584	glycerophosphoryl diester phosphodiesterase
CG482_021495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_021500	COG2801	Transposase and inactivated derivatives
CG482_021505	COG1404	Belongs to the peptidase S8 family
CG482_021525	COG1994	Peptidase M50
CG482_021540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG482_021545	COG1120	ATPase activity
CG482_021550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_021555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_021560	COG4844	belongs to the
CG482_021575	COG0280	phosphate acetyltransferase
CG482_021590	COG3773	Cell wall hydrolase
CG482_021600	COG2363	Small membrane protein
CG482_021610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG482_021615	COG2233	PERMEase
CG482_021620	COG0561	phosphatase activity
CG482_021625	COG2814	Major facilitator Superfamily
CG482_021630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG482_021635	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG482_021640	COG1131	(ABC) transporter
CG482_021650	COG0460	homoserine dehydrogenase
CG482_021655	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CG482_021670	COG0351	phosphomethylpyrimidine kinase
CG482_021680	COG1966	Carbon starvation protein
CG482_021685	COG3279	Response regulator of the LytR AlgR family
CG482_021695	COG0477	Major facilitator Superfamily
CG482_021705	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CG482_021710	COG0438	transferase activity, transferring glycosyl groups
CG482_021725	COG0840	transmembrane signaling receptor activity
CG482_021750	COG1607	acyl-coa hydrolase
CG482_021755	COG1216	Glycosyl transferase, family 2
CG482_021770	COG0463	Glycosyl transferase, family 2
CG482_021785	COG0463	Glycosyl transferase, family 2
CG482_021790	COG0488	(ABC) transporter
CG482_021795	COG1309	transcriptional regulator
CG482_021800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG482_021805	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG482_021805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG482_021810	COG0628	permease
CG482_021815	COG1346	cytolysis
CG482_021825	COG3279	Response regulator of the LytR AlgR family
CG482_021830	COG3275	phosphorelay sensor kinase activity
CG482_021835	COG2814	Major facilitator Superfamily
CG482_021840	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CG482_021845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG482_021855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG482_021860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_021860	COG3711	transcriptional antiterminator
CG482_021950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG482_021960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG482_021965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CG482_021970	COG4853	Protein conserved in bacteria
CG482_021980	COG5002	protein histidine kinase activity
CG482_021985	COG0745	RESPONSE REGULATOR receiver
CG482_022010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG482_022015	COG0305	Participates in initiation and elongation during chromosome replication
CG482_022020	COG0359	binds to the 23S rRNA
CG482_022025	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CG482_022030	COG4241	membrane
CG482_022035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CG482_022040	COG0629	single-stranded DNA binding
CG482_022045	COG0360	Binds together with S18 to 16S ribosomal RNA
CG482_022050	COG0012	GTP binding
CG482_022055	COG4481	Protein conserved in bacteria
CG482_022060	COG0668	transmembrane transport
CG482_022070	COG1475	DNA binding
CG482_022075	COG1192	Involved in chromosome partitioning
CG482_022080	COG1475	DNA binding
CG482_022085	COG0357	Ribosomal RNA small subunit methyltransferase G
CG482_022090	COG0445	tRNA wobble uridine modification
CG482_022095	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG482_022100	COG1847	R3H domain protein
CG482_022105	COG0706	membrane insertase activity
CG482_022110	COG0594	ribonuclease P activity
CG482_022210	COG0457	Tetratricopeptide repeat
CG482_022245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG482_022250	COG3209	COG3209 Rhs family protein
CG482_022265	COG2003	Belongs to the UPF0758 family
CG482_022500	COG4974	Belongs to the 'phage' integrase family
CG482_022535	COG4166	transmembrane transport
CG482_022545	COG0457	Tetratricopeptide repeat
CG482_022585	COG1192	Involved in chromosome partitioning
CG482_022680	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_022700	COG0583	DNA-binding transcription factor activity
CG482_022745	COG0741	lytic transglycosylase activity
CG482_022745	COG0791	NLP P60 protein