locus-tag	class	description
CG483_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG483_000010	COG0592	DNA-directed DNA polymerase activity
CG483_000015	COG2501	S4 domain
CG483_000020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG483_000025	COG0187	DNA topoisomerase II activity
CG483_000030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG483_000065	COG0516	GMP reductase activity
CG483_000065	COG0517	IMP dehydrogenase activity
CG483_000070	COG1686	Belongs to the peptidase S11 family
CG483_000075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CG483_000080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CG483_000085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG483_000100	COG1428	Deoxynucleoside kinase
CG483_000105	COG1428	Deoxynucleoside kinase
CG483_000110	COG1335	isochorismatase
CG483_000115	COG0590	tRNA wobble adenosine to inosine editing
CG483_000125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG483_000130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG483_000135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG483_000180	COG1982	Orn Lys Arg decarboxylase major
CG483_000185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG483_000190	COG0470	DNA polymerase III
CG483_000195	COG1774	PSP1 C-terminal conserved region
CG483_000200	COG4467	Involved in initiation control of chromosome replication
CG483_000205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CG483_000215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CG483_000220	COG2002	toxin-antitoxin pair type II binding
CG483_000230	COG0084	hydrolase, TatD family'
CG483_000240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG483_000250	COG4466	Protein conserved in bacteria
CG483_000260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CG483_000265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG483_000270	COG0251	oxidation-reduction process
CG483_000275	COG2088	sporulation resulting in formation of a cellular spore
CG483_000280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG483_000285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CG483_000290	COG0193	aminoacyl-tRNA hydrolase activity
CG483_000300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG483_000305	COG2002	toxin-antitoxin pair type II binding
CG483_000310	COG2244	polysaccharide biosynthetic process
CG483_000315	COG3956	TIGRFAM MazG family protein
CG483_000320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CG483_000340	COG1098	S1 RNA binding domain
CG483_000370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG483_000375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CG483_000380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG483_000385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG483_000390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CG483_000395	COG0512	Glutamine amidotransferase of anthranilate synthase
CG483_000400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG483_000405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CG483_000410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CG483_000415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CG483_000420	COG1396	sequence-specific DNA binding
CG483_000425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG483_000430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG483_000465	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG483_000515	COG3880	PFAM UvrB UvrC protein
CG483_000520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CG483_000525	COG0542	response to heat
CG483_000530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CG483_000540	COG4956	integral membrane protein (PIN domain superfamily)
CG483_000545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG483_000550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG483_000555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG483_000560	COG1045	serine acetyltransferase
CG483_000565	COG0215	cysteine-tRNA ligase activity
CG483_000575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG483_000580	COG3688	RNA-binding protein containing a PIN domain
CG483_000600	COG0250	Participates in transcription elongation, termination and antitermination
CG483_000610	COG0081	regulation of translation
CG483_000615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG483_000620	COG0222	ribosome binding
CG483_000625	COG2813	Specifically methylates the guanine in position
CG483_000635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG483_000640	COG1358	cellular component organization or biogenesis
CG483_000645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CG483_000650	COG0049	tRNA binding
CG483_000655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG483_000660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG483_000670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CG483_000675	COG0088	Forms part of the polypeptide exit tunnel
CG483_000680	COG0089	rRNA binding
CG483_000685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CG483_000690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG483_000695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CG483_000700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CG483_000705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CG483_000715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG483_000720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG483_000725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CG483_000730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CG483_000740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG483_000745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CG483_000750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CG483_000755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CG483_000760	COG1841	ribosomal large subunit assembly
CG483_000765	COG0200	Binds to the 23S rRNA
CG483_000770	COG0201	protein transport
CG483_000775	COG0563	adenylate kinase activity
CG483_000780	COG0024	Methionine aminopeptidase
CG483_000790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG483_000800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG483_000805	COG0202	RNA polymerase activity
CG483_000820	COG1122	ATPase activity
CG483_000825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG483_000835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG483_000840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CG483_000850	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG483_000855	COG0489	protein tyrosine kinase activity
CG483_000865	COG2194	sulfuric ester hydrolase activity
CG483_000870	COG0726	polysaccharide deacetylase
CG483_000900	COG4974	Belongs to the 'phage' integrase family
CG483_001055	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CG483_001065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG483_001105	COG1396	sequence-specific DNA binding
CG483_001110	COG0602	queuosine metabolic process
CG483_001225	COG3681	Belongs to the UPF0597 family
CG483_001230	COG3681	Belongs to the UPF0597 family
CG483_001255	COG2814	Major facilitator Superfamily
CG483_001265	COG0601	transmembrane transport
CG483_001270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG483_001275	COG0444	Belongs to the ABC transporter superfamily
CG483_001280	COG4608	Belongs to the ABC transporter superfamily
CG483_001285	COG4166	transmembrane transport
CG483_001295	COG2207	Transcriptional regulator
CG483_001305	COG1309	transcriptional regulator
CG483_001315	COG0656	L-ascorbic acid biosynthetic process
CG483_001320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG483_001330	COG4149	molybdate abc transporter
CG483_001335	COG0725	ABC transporter, periplasmic molybdate-binding protein
CG483_001340	COG1910	domain protein
CG483_001345	COG0204	Acyl-transferase
CG483_001350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG483_001355	COG1648	precorrin-2 dehydrogenase activity
CG483_001355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG483_001365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG483_001365	COG1587	Uroporphyrinogen-III synthase
CG483_001370	COG2146	nitrite reductase [NAD(P)H] activity
CG483_001375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG483_001405	COG4585	Histidine kinase
CG483_001410	COG2197	response regulator
CG483_001415	COG1131	(ABC) transporter
CG483_001420	COG1511	domain protein
CG483_001420	COG0842	Transport permease protein
CG483_001435	COG0747	negative chemotaxis
CG483_001440	COG0601	transmembrane transport
CG483_001445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG483_001450	COG0444	Belongs to the ABC transporter superfamily
CG483_001455	COG4608	Belongs to the ABC transporter superfamily
CG483_001460	COG0561	phosphatase activity
CG483_001480	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CG483_001485	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG483_001495	COG2814	Major facilitator Superfamily
CG483_001500	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG483_001505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CG483_001515	COG0705	Rhomboid family
CG483_001515	COG0457	Tetratricopeptide repeat
CG483_001520	COG0736	holo-[acyl-carrier-protein] synthase activity
CG483_001525	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG483_001535	COG0864	Transcriptional regulator
CG483_001540	COG2337	Toxic component of a toxin-antitoxin (TA) module
CG483_001545	COG2183	response to ionizing radiation
CG483_001555	COG3091	SprT-like family
CG483_001595	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG483_001645	COG0802	atpase or kinase
CG483_001650	COG1214	PFAM Peptidase M22, glycoprotease
CG483_001655	COG0456	acetyltransferase
CG483_001665	COG0488	(ABC) transporter
CG483_001670	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CG483_001680	COG1266	CAAX protease self-immunity
CG483_001685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CG483_001690	COG0459	protein refolding
CG483_001695	COG0519	Catalyzes the synthesis of GMP from XMP
CG483_001695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG483_001700	COG2252	PERMEase
CG483_001710	COG5002	protein histidine kinase activity
CG483_001780	COG2205	protein histidine kinase activity
CG483_001785	COG0745	RESPONSE REGULATOR receiver
CG483_001805	COG0697	spore germination
CG483_001830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG483_001835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG483_001840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG483_001845	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG483_001850	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG483_001855	COG0047	phosphoribosylformylglycinamidine synthase activity
CG483_001860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG483_001865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CG483_001870	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG483_001875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG483_001880	COG0138	bifunctional purine biosynthesis protein purh
CG483_001885	COG0151	Belongs to the GarS family
CG483_001895	COG0583	DNA-binding transcription factor activity
CG483_001915	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CG483_001920	COG0210	DNA helicase
CG483_001925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CG483_001930	COG4851	CamS sex pheromone cAM373 precursor
CG483_001940	COG1012	belongs to the aldehyde dehydrogenase family
CG483_001945	COG1335	isochorismatase
CG483_001955	COG2011	ABC-type metal ion transport system permease component
CG483_001960	COG1464	Belongs to the NlpA lipoprotein family
CG483_001975	COG4682	membrane
CG483_001980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG483_001985	COG0154	amidase activity
CG483_001990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG483_001995	COG1597	lipid kinase activity
CG483_002000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG483_002005	COG0546	phosphoglycolate phosphatase activity
CG483_002010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG483_002020	COG0531	amino acid
CG483_002025	COG1012	belongs to the aldehyde dehydrogenase family
CG483_002030	COG2076	Multidrug Resistance protein
CG483_002035	COG2309	aminopeptidase activity
CG483_002050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG483_002055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG483_002060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG483_002075	COG0450	alkyl hydroperoxide reductase
CG483_002100	COG0714	Associated with various cellular activities
CG483_002135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG483_002140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG483_002145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG483_002150	COG0492	ferredoxin-NADP+ reductase activity
CG483_002160	COG0166	Belongs to the GPI family
CG483_002165	COG5002	protein histidine kinase activity
CG483_002190	COG3541	Predicted nucleotidyltransferase
CG483_002195	COG2814	Major facilitator Superfamily
CG483_002200	COG0723	plastoquinol--plastocyanin reductase activity
CG483_002200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG483_002210	COG0765	amino acid transport
CG483_002215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG483_002220	COG1126	abc transporter atp-binding protein
CG483_002225	COG0840	transmembrane signaling receptor activity
CG483_002240	COG2235	arginine
CG483_002255	COG0549	Belongs to the carbamate kinase family
CG483_002270	COG0366	Alpha amylase catalytic
CG483_002275	COG1263	PTS System
CG483_002275	COG2190	(PTS) system
CG483_002275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG483_002295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG483_002300	COG4605	iron ion homeostasis
CG483_002305	COG4604	ABC transporter, ATP-binding protein
CG483_002310	COG4607	ABC-type enterochelin transport system periplasmic component
CG483_002315	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CG483_002320	COG0352	thiamine-phosphate diphosphorylase activity
CG483_002325	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CG483_002345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG483_002355	COG1116	anion transmembrane transporter activity
CG483_002435	COG2963	transposase activity
CG483_002440	COG2801	Transposase and inactivated derivatives
CG483_002445	COG2270	Major facilitator Superfamily
CG483_002470	COG2310	stress, protein
CG483_002475	COG2310	stress, protein
CG483_002480	COG2310	stress, protein
CG483_002485	COG0861	Integral membrane protein TerC family
CG483_002495	COG3853	Toxic anion resistance protein (TelA)
CG483_002505	COG4840	Belongs to the UPF0435 family
CG483_002510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG483_002520	COG1295	ribonuclease BN
CG483_002525	COG2217	Heavy metal translocating P-type atpase
CG483_002530	COG0697	spore germination
CG483_002540	COG0681	Belongs to the peptidase S26 family
CG483_002550	COG0586	Pfam SNARE associated Golgi protein
CG483_002565	COG0387	Pfam Sodium calcium exchanger
CG483_002575	COG0535	radical SAM domain protein
CG483_002595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CG483_002620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG483_002645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG483_002675	COG2066	Belongs to the glutaminase family
CG483_002680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG483_002680	COG1263	PTS System
CG483_002685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG483_002695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG483_002695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG483_002705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CG483_002710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG483_002725	COG0402	S-adenosylhomocysteine deaminase activity
CG483_002730	COG2137	regulation of response to DNA damage stimulus
CG483_002755	COG1988	membrane-bound metal-dependent
CG483_002760	COG1194	a g-specific adenine glycosylase
CG483_002785	COG3557	Belongs to the UPF0374 family
CG483_002790	COG1132	(ABC) transporter
CG483_002795	COG4129	membrane
CG483_002800	COG0067	glutamate synthase
CG483_002800	COG0070	glutamate synthase
CG483_002800	COG0069	glutamate synthase activity
CG483_002805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG483_002810	COG4555	ABC transporter
CG483_002830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG483_002835	COG0735	belongs to the Fur family
CG483_002935	COG3157	Type VI secretion system effector, Hcp
CG483_002955	COG0457	Tetratricopeptide repeat
CG483_002960	COG0217	transcriptional regulatory protein
CG483_002965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG483_002970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG483_002990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CG483_003000	COG2766	serine protein kinase
CG483_003025	COG1280	lysine exporter protein (LysE YggA)
CG483_003065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG483_003075	COG1585	Membrane protein implicated in regulation of membrane protease activity
CG483_003080	COG2268	Band 7 protein
CG483_003110	COG4990	cell redox homeostasis
CG483_003120	COG3290	protein histidine kinase activity
CG483_003125	COG4565	transcriptional regulatory protein
CG483_003130	COG3493	citrate carrier protein
CG483_003135	COG0281	malic enzyme
CG483_003150	COG5002	protein histidine kinase activity
CG483_003155	COG0745	RESPONSE REGULATOR receiver
CG483_003165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CG483_003170	COG3383	formate dehydrogenase (NAD+) activity
CG483_003175	COG2427	Protein of unknown function (DUF1641)
CG483_003185	COG0840	transmembrane signaling receptor activity
CG483_003195	COG0531	amino acid
CG483_003210	COG0640	Transcriptional regulator
CG483_003215	COG2217	Heavy metal translocating P-type atpase
CG483_003220	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG483_003230	COG3227	Zinc metalloprotease (Elastase)
CG483_003245	COG2217	Heavy metal translocating P-type atpase
CG483_003265	COG2720	vancomycin resistance protein
CG483_003270	COG1316	TRANSCRIPTIONal
CG483_003280	COG1253	flavin adenine dinucleotide binding
CG483_003285	COG1027	Aspartate ammonia-lyase
CG483_003290	COG1620	l-lactate permease
CG483_003310	COG3104	oligopeptide transport
CG483_003315	COG0156	8-amino-7-oxononanoate synthase activity
CG483_003320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG483_003335	COG4548	von Willebrand factor, type A
CG483_003340	COG0714	Associated with various cellular activities
CG483_003345	COG0531	amino acid
CG483_003350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG483_003355	COG1115	amino acid carrier protein
CG483_003365	COG1126	abc transporter atp-binding protein
CG483_003370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG483_003375	COG0765	amino acid transport
CG483_003380	COG0765	amino acid transport
CG483_003385	COG0833	amino acid
CG483_003395	COG5002	protein histidine kinase activity
CG483_003400	COG0745	RESPONSE REGULATOR receiver
CG483_003410	COG0659	secondary active sulfate transmembrane transporter activity
CG483_003415	COG0589	response to stress
CG483_003425	COG0747	negative chemotaxis
CG483_003435	COG0601	transmembrane transport
CG483_003440	COG4608	Belongs to the ABC transporter superfamily
CG483_003450	COG2271	Major facilitator Superfamily
CG483_003455	COG1846	Transcriptional regulator
CG483_003460	COG0477	Major facilitator Superfamily
CG483_003465	COG1609	Transcriptional regulator
CG483_003470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG483_003475	COG1869	D-ribose catabolic process
CG483_003480	COG1129	ABC transporter
CG483_003485	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG483_003490	COG1879	ABC-type sugar transport system periplasmic component
CG483_003495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CG483_003535	COG3568	Endonuclease Exonuclease Phosphatase
CG483_003560	COG0840	transmembrane signaling receptor activity
CG483_003565	COG3584	3D domain protein
CG483_003565	COG3583	domain protein
CG483_003570	COG1476	TRANSCRIPTIONal
CG483_003600	COG1114	Component of the transport system for branched-chain amino acids
CG483_003610	COG1113	amino acid transport
CG483_003615	COG2153	protein acetylation
CG483_003625	COG0569	domain protein
CG483_003625	COG0475	glutathione-regulated potassium exporter activity
CG483_003640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG483_003645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CG483_003650	COG0833	amino acid
CG483_003655	COG4990	cell redox homeostasis
CG483_003670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG483_003675	COG0697	spore germination
CG483_003680	COG0531	amino acid
CG483_003695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG483_003700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG483_003705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG483_003705	COG1918	ferrous iron import across plasma membrane
CG483_003710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG483_003715	COG0573	inorganic phosphate transmembrane transporter activity
CG483_003720	COG0581	inorganic phosphate transmembrane transporter activity
CG483_003725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG483_003765	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG483_003850	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CG483_003875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG483_003880	COG1116	anion transmembrane transporter activity
CG483_003885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG483_003890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG483_003895	COG0352	thiamine-phosphate diphosphorylase activity
CG483_003900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG483_003905	COG2104	thiamine diphosphate biosynthetic process
CG483_003910	COG2022	thiamine diphosphate biosynthetic process
CG483_003915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG483_003920	COG0351	phosphomethylpyrimidine kinase
CG483_003950	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CG483_003955	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CG483_003960	COG2205	protein histidine kinase activity
CG483_003970	COG4974	Belongs to the 'phage' integrase family
CG483_003990	COG0735	belongs to the Fur family
CG483_004015	COG1846	Transcriptional regulator
CG483_004025	COG2252	PERMEase
CG483_004030	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_004035	COG1376	ErfK ybiS ycfS ynhG family protein
CG483_004060	COG1316	TRANSCRIPTIONal
CG483_004090	COG0778	Nitroreductase
CG483_004100	COG2719	SpoVR family
CG483_004110	COG1316	TRANSCRIPTIONal
CG483_004115	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG483_004130	COG0577	efflux transmembrane transporter activity
CG483_004135	COG1136	(ABC) transporter
CG483_004145	COG1114	Component of the transport system for branched-chain amino acids
CG483_004150	COG3546	catalase activity
CG483_004205	COG0475	glutathione-regulated potassium exporter activity
CG483_004210	COG1737	Transcriptional regulator
CG483_004220	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CG483_004225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG483_004225	COG1263	PTS System
CG483_004270	COG1522	sequence-specific DNA binding
CG483_004285	COG0531	amino acid
CG483_004295	COG1012	belongs to the aldehyde dehydrogenase family
CG483_004300	COG1132	(ABC) transporter
CG483_004305	COG1132	(ABC) transporter
CG483_004315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG483_004320	COG0765	amino acid transport
CG483_004325	COG1126	abc transporter atp-binding protein
CG483_004340	COG0189	ligase activity
CG483_004345	COG4399	Belongs to the UPF0754 family
CG483_004350	COG3679	Belongs to the UPF0342 family
CG483_004355	COG4585	Histidine kinase
CG483_004360	COG2197	response regulator
CG483_004420	COG2094	Belongs to the DNA glycosylase MPG family
CG483_004425	COG0561	phosphatase activity
CG483_004435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG483_004440	COG0318	PFAM AMP-dependent synthetase and ligase
CG483_004465	COG2244	polysaccharide biosynthetic process
CG483_004475	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG483_004495	COG1696	Membrane protein involved in D-alanine export
CG483_004510	COG1024	Enoyl-CoA hydratase
CG483_004525	COG1363	Peptidase, m42
CG483_004540	COG2239	Acts as a magnesium transporter
CG483_004550	COG1115	amino acid carrier protein
CG483_004675	COG1476	TRANSCRIPTIONal
CG483_004720	COG1131	(ABC) transporter
CG483_004765	COG0494	nUDIX hydrolase
CG483_004780	COG1061	Type III restriction enzyme res subunit
CG483_004795	COG4638	Rieske (2fe-2S)
CG483_004800	COG1012	belongs to the aldehyde dehydrogenase family
CG483_004805	COG0473	3-isopropylmalate dehydrogenase activity
CG483_004815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG483_004825	COG1064	alcohol dehydrogenase
CG483_004840	COG3246	L-lysine catabolic process to acetate
CG483_004885	COG4641	Protein conserved in bacteria
CG483_004900	COG3711	transcriptional antiterminator
CG483_004905	COG2190	(PTS) system
CG483_004905	COG1263	PTS System
CG483_004905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG483_004910	COG2723	6-phospho-beta-galactosidase activity
CG483_004920	COG2376	Dihydroxyacetone kinase
CG483_004925	COG0393	Putative heavy-metal-binding
CG483_004955	COG0420	3'-5' exonuclease activity
CG483_004960	COG4717	serine-type aminopeptidase activity
CG483_004965	COG3481	metal-dependent phosphohydrolase, HD sub domain
CG483_004980	COG0577	efflux transmembrane transporter activity
CG483_004985	COG1136	(ABC) transporter
CG483_004990	COG5002	protein histidine kinase activity
CG483_004995	COG0745	RESPONSE REGULATOR receiver
CG483_005005	COG1316	TRANSCRIPTIONal
CG483_005020	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CG483_005025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CG483_005030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG483_005035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CG483_005055	COG1846	Transcriptional regulator
CG483_005060	COG4980	gas vesicle protein
CG483_005070	COG0537	adenosine 5'-monophosphoramidase activity
CG483_005075	COG1131	(ABC) transporter
CG483_005080	COG4473	ABC transporter
CG483_005100	COG3402	PFAM membrane-flanked domain
CG483_005110	COG2329	Antibiotic biosynthesis monooxygenase
CG483_005115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG483_005120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CG483_005160	COG1309	transcriptional regulator
CG483_005170	COG1216	Glycosyl transferase, family 2
CG483_005170	COG0438	transferase activity, transferring glycosyl groups
CG483_005180	COG1609	Transcriptional regulator
CG483_005190	COG1234	tRNA 3'-trailer cleavage
CG483_005195	COG0095	Lipoate-protein ligase
CG483_005205	COG0318	PFAM AMP-dependent synthetase and ligase
CG483_005220	COG2205	protein histidine kinase activity
CG483_005225	COG0745	RESPONSE REGULATOR receiver
CG483_005245	COG0501	Belongs to the peptidase M48B family
CG483_005250	COG0840	transmembrane signaling receptor activity
CG483_005255	COG0697	spore germination
CG483_005275	COG2224	Isocitrate lyase
CG483_005280	COG1278	Cold shock
CG483_005285	COG4903	ComK protein
CG483_005290	COG0398	Pfam SNARE associated Golgi protein
CG483_005300	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CG483_005305	COG1074	ATP-dependent DNA helicase activity
CG483_005345	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG483_005365	COG0367	asparagine synthase
CG483_005375	COG0753	catalase activity
CG483_005385	COG0366	Alpha amylase catalytic
CG483_005385	COG1874	Beta-galactosidase
CG483_005390	COG1666	GTP binding
CG483_005395	COG2996	Protein conserved in bacteria
CG483_005410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG483_005425	COG0561	phosphatase activity
CG483_005450	COG2267	carboxylic ester hydrolase activity
CG483_005465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG483_005470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG483_005475	COG5504	Zn-dependent protease
CG483_005485	COG0180	Tryptophanyl-tRNA synthetase
CG483_005500	COG4166	transmembrane transport
CG483_005505	COG0601	transmembrane transport
CG483_005510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG483_005515	COG0444	Belongs to the ABC transporter superfamily
CG483_005520	COG4608	Belongs to the ABC transporter superfamily
CG483_005525	COG0534	Mate efflux family protein
CG483_005530	COG4166	transmembrane transport
CG483_005550	COG1393	Belongs to the ArsC family
CG483_005555	COG0861	Integral membrane protein TerC family
CG483_005575	COG1164	Oligoendopeptidase f
CG483_005590	COG2346	COG2346, Truncated hemoglobins
CG483_005595	COG4116	CYTH
CG483_005605	COG2357	RelA SpoT domain protein
CG483_005615	COG0564	pseudouridine synthase activity
CG483_005625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG483_005630	COG0772	Belongs to the SEDS family
CG483_005675	COG1216	Glycosyl transferase, family 2
CG483_005700	COG0457	Tetratricopeptide repeat
CG483_005700	COG0463	Glycosyl transferase, family 2
CG483_005720	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CG483_005735	COG1091	dTDP-4-dehydrorhamnose reductase activity
CG483_005760	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CG483_005765	COG2382	esterase
CG483_005780	COG5492	domain, Protein
CG483_005785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG483_005800	COG1620	l-lactate permease
CG483_005805	COG5634	Uncharacterized conserved protein (DUF2278)
CG483_005845	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG483_005850	COG0567	Dehydrogenase, E1 component
CG483_005860	COG0583	DNA-binding transcription factor activity
CG483_005865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG483_005870	COG1012	belongs to the aldehyde dehydrogenase family
CG483_005885	COG0196	riboflavin kinase activity
CG483_005890	COG3162	membrane
CG483_005895	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG483_005900	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG483_005915	COG0457	Tetratricopeptide repeat
CG483_005980	COG0673	inositol 2-dehydrogenase activity
CG483_006010	COG0457	Tetratricopeptide repeat
CG483_006015	COG0582	viral genome integration into host DNA
CG483_006065	COG0582	viral genome integration into host DNA
CG483_006090	COG1686	Belongs to the peptidase S11 family
CG483_006095	COG0681	Belongs to the peptidase S26 family
CG483_006130	COG1012	belongs to the aldehyde dehydrogenase family
CG483_006140	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG483_006145	COG1177	transmembrane transport
CG483_006150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG483_006155	COG0671	phosphoesterase, PA-phosphatase related
CG483_006160	COG2409	Drug exporters of the RND superfamily
CG483_006170	COG0564	pseudouridine synthase activity
CG483_006180	COG2340	Cysteine-rich secretory protein family
CG483_006185	COG0247	lactate metabolic process
CG483_006190	COG0277	FAD linked oxidase domain protein
CG483_006195	COG3835	regulator
CG483_006205	COG0745	RESPONSE REGULATOR receiver
CG483_006210	COG5002	protein histidine kinase activity
CG483_006215	COG2186	Transcriptional regulator
CG483_006220	COG0247	lactate metabolic process
CG483_006225	COG1139	Iron-sulfur cluster binding protein
CG483_006230	COG1556	Lactate utilization protein
CG483_006235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CG483_006240	COG0584	glycerophosphoryl diester phosphodiesterase
CG483_006255	COG2267	carboxylic ester hydrolase activity
CG483_006260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG483_006285	COG2116	formate transmembrane transporter activity
CG483_006290	COG0861	Integral membrane protein TerC family
CG483_006295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG483_006305	COG2030	dehydratase
CG483_006325	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_006330	COG3243	poly(R)-hydroxyalkanoic acid synthase
CG483_006335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG483_006350	COG1840	ABC-type Fe3 transport system, periplasmic component
CG483_006355	COG3842	ATPase activity
CG483_006365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG483_006370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CG483_006375	COG1349	DNA-binding transcription factor activity
CG483_006380	COG0235	Class ii aldolase
CG483_006390	COG2861	carbohydrate metabolic process
CG483_006400	COG3852	Histidine kinase
CG483_006405	COG1846	Transcriptional regulator
CG483_006425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CG483_006430	COG0720	synthase
CG483_006440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG483_006445	COG4873	Protein conserved in bacteria
CG483_006455	COG0456	acetyltransferase
CG483_006475	COG1780	Probably involved in ribonucleotide reductase function
CG483_006490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG483_006495	COG1725	Transcriptional regulator
CG483_006500	COG1131	(ABC) transporter
CG483_006510	COG1131	(ABC) transporter
CG483_006515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG483_006530	COG1522	sequence-specific DNA binding
CG483_006545	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG483_006550	COG2070	2-Nitropropane dioxygenase
CG483_006555	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CG483_006565	COG1696	Membrane protein involved in D-alanine export
CG483_006570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG483_006585	COG0716	FMN binding
CG483_006610	COG1368	sulfuric ester hydrolase activity
CG483_006620	COG3173	Aminoglycoside phosphotransferase
CG483_006635	COG5609	conserved protein (DUF2294)
CG483_006640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG483_006645	COG3002	Belongs to the UPF0753 family
CG483_006650	COG0288	reversible hydration of carbon dioxide
CG483_006655	COG0534	Mate efflux family protein
CG483_006670	COG1846	Transcriptional regulator
CG483_006680	COG1301	dicarboxylic acid transport
CG483_006685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG483_006695	COG3874	Sporulation protein YtfJ
CG483_006720	COG0028	Belongs to the TPP enzyme family
CG483_006725	COG0440	acetolactate synthase activity
CG483_006730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CG483_006735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG483_006745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG483_006750	COG0066	3-isopropylmalate dehydratase activity
CG483_006760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CG483_006770	COG0131	Imidazoleglycerol-phosphate dehydratase
CG483_006775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG483_006780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CG483_006785	COG0107	imidazoleglycerol-phosphate synthase activity
CG483_006790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG483_006795	COG0140	phosphoribosyl-ATP diphosphatase activity
CG483_006810	COG1183	phosphatidylcholine synthase activity
CG483_006815	COG1368	sulfuric ester hydrolase activity
CG483_006825	COG0019	diaminopimelate decarboxylase activity
CG483_006835	COG0175	sulfate reduction
CG483_006840	COG2046	Belongs to the sulfate adenylyltransferase family
CG483_006845	COG0529	Catalyzes the synthesis of activated sulfate
CG483_006850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG483_006870	COG1648	precorrin-2 dehydrogenase activity
CG483_006870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG483_006875	COG0733	neurotransmitter:sodium symporter activity
CG483_006890	COG3557	Belongs to the UPF0374 family
CG483_006895	COG1757	Na H antiporter
CG483_006910	COG4758	membrane
CG483_006915	COG4585	Histidine kinase
CG483_006920	COG2197	response regulator
CG483_006925	COG1114	Component of the transport system for branched-chain amino acids
CG483_006930	COG1525	nuclease
CG483_006930	COG4085	toxin activity
CG483_006930	COG0737	Belongs to the 5'-nucleotidase family
CG483_006960	COG3711	transcriptional antiterminator
CG483_006970	COG2723	6-phospho-beta-galactosidase activity
CG483_006985	COG3711	transcriptional antiterminator
CG483_006985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG483_006990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG483_006990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG483_006990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG483_006995	COG1482	cell wall glycoprotein biosynthetic process
CG483_007005	COG2801	Transposase and inactivated derivatives
CG483_007025	COG0730	response to heat
CG483_007030	COG0306	phosphate transporter
CG483_007035	COG1392	Phosphate transport regulator
CG483_007040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG483_007050	COG3852	Histidine kinase
CG483_007055	COG1801	Protein of unknown function DUF72
CG483_007065	COG0582	viral genome integration into host DNA
CG483_007070	COG5002	protein histidine kinase activity
CG483_007075	COG0813	purine-nucleoside phosphorylase activity
CG483_007085	COG0392	lysyltransferase activity
CG483_007085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CG483_007105	COG1686	Belongs to the peptidase S11 family
CG483_007110	COG2715	membrane protein required for spore maturation
CG483_007115	COG0700	Nucleoside recognition
CG483_007120	COG1187	pseudouridine synthase activity
CG483_007130	COG1333	cytochrome c biogenesis protein
CG483_007135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG483_007140	COG0745	RESPONSE REGULATOR receiver
CG483_007145	COG5002	protein histidine kinase activity
CG483_007150	COG2096	Adenosyltransferase
CG483_007165	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CG483_007170	COG1141	Ferredoxin
CG483_007180	COG0514	ATP-dependent DNA helicase (RecQ)
CG483_007185	COG1266	CAAX protease self-immunity
CG483_007195	COG1408	metallophosphoesterase
CG483_007210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG483_007225	COG0492	ferredoxin-NADP+ reductase activity
CG483_007240	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG483_007250	COG1304	FMN binding
CG483_007275	COG1160	GTP binding
CG483_007280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG483_007300	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG483_007310	COG0302	gtp cyclohydrolase
CG483_007315	COG0142	geranyltranstransferase activity
CG483_007320	COG2226	methyltransferase
CG483_007325	COG0142	geranyltranstransferase activity
CG483_007330	COG0105	UTP biosynthetic process
CG483_007335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG483_007340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CG483_007345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG483_007350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG483_007355	COG0457	Tetratricopeptide repeat
CG483_007360	COG5582	Belongs to the UPF0302 family
CG483_007375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG483_007385	COG4347	Protein of unknown function (DUF1405)
CG483_007400	COG2738	Putative neutral zinc metallopeptidase
CG483_007410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG483_007415	COG1694	Mazg nucleotide pyrophosphohydrolase
CG483_007420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CG483_007425	COG1803	Methylglyoxal synthase
CG483_007430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG483_007435	COG0438	transferase activity, transferring glycosyl groups
CG483_007440	COG0617	tRNA 3'-terminal CCA addition
CG483_007455	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CG483_007460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG483_007465	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CG483_007470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG483_007470	COG1199	ATP-dependent helicase activity
CG483_007490	COG3935	DnaD domain protein
CG483_007495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG483_007505	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG483_007505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG483_007510	COG3331	DNA recombination
CG483_007545	COG4474	Belongs to the UPF0398 family
CG483_007550	COG3599	regulation of cell shape
CG483_007560	COG0116	Belongs to the methyltransferase superfamily
CG483_007570	COG1199	ATP-dependent helicase activity
CG483_007575	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CG483_007580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG483_007585	COG2233	PERMEase
CG483_007590	COG2311	Membrane
CG483_007595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG483_007605	COG0456	acetyltransferase
CG483_007645	COG3766	membrane
CG483_007650	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG483_007655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG483_007660	COG1733	regulation of RNA biosynthetic process
CG483_007680	COG0328	RNA-DNA hybrid ribonuclease activity
CG483_007710	COG1278	Cold shock
CG483_007720	COG3162	membrane
CG483_007725	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG483_007730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG483_007735	COG0475	glutathione-regulated potassium exporter activity
CG483_007740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG483_007765	COG2323	membrane
CG483_007770	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CG483_007795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG483_007805	COG2201	protein-glutamate methylesterase activity
CG483_007810	COG2198	Histidine kinase
CG483_007810	COG0643	Histidine kinase
CG483_007815	COG1776	CheC inhibitor of MCP methylation
CG483_007815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG483_007830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CG483_007850	COG1256	bacterial-type flagellum assembly
CG483_007855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG483_007860	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CG483_007875	COG1815	bacterial-type flagellum-dependent cell motility
CG483_007880	COG1558	bacterial-type flagellum-dependent cell motility
CG483_007885	COG1677	Flagellar hook-basal body complex protein FliE
CG483_007895	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG483_007905	COG1157	protein secretion by the type III secretion system
CG483_007940	COG0784	Response regulator, receiver
CG483_007940	COG0835	chemotaxis
CG483_007950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG483_007955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG483_007960	COG0741	lytic transglycosylase activity
CG483_007970	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG483_007975	COG1776	CheC inhibitor of MCP methylation
CG483_007975	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG483_007985	COG1338	Plays a role in the flagellum-specific transport system
CG483_007990	COG1987	bacterial-type flagellum assembly
CG483_008000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG483_008005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG483_008010	COG1419	protein localization to endoplasmic reticulum
CG483_008015	COG4786	Flagellar basal body rod
CG483_008020	COG0577	efflux transmembrane transporter activity
CG483_008020	COG1136	(ABC) transporter
CG483_008070	COG2814	Major facilitator Superfamily
CG483_008080	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_008115	COG0367	asparagine synthase
CG483_008135	COG1802	Transcriptional regulator
CG483_008140	COG0697	spore germination
CG483_008150	COG1757	Na H antiporter
CG483_008160	COG0114	fumarate hydratase activity
CG483_008185	COG0534	Mate efflux family protein
CG483_008190	COG3340	Belongs to the peptidase S51 family
CG483_008195	COG2733	membrane
CG483_008205	COG1280	lysine exporter protein (LysE YggA)
CG483_008210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG483_008225	COG2502	aspartate--ammonia ligase
CG483_008235	COG0109	protoheme IX farnesyltransferase activity
CG483_008265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG483_008275	COG4166	transmembrane transport
CG483_008280	COG2223	nitrite transmembrane transporter activity
CG483_008285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG483_008290	COG2244	polysaccharide biosynthetic process
CG483_008295	COG0733	neurotransmitter:sodium symporter activity
CG483_008300	COG5566	PFAM Mor transcription activator
CG483_008315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG483_008320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG483_008330	COG0129	dihydroxy-acid dehydratase activity
CG483_008335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG483_008365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG483_008370	COG2814	Major facilitator Superfamily
CG483_008375	COG3384	dioxygenase
CG483_008395	COG0402	S-adenosylhomocysteine deaminase activity
CG483_008400	COG4166	transmembrane transport
CG483_008410	COG1914	H( )-stimulated, divalent metal cation uptake system
CG483_008425	COG0083	homoserine kinase activity
CG483_008435	COG2390	Transcriptional regulator
CG483_008440	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CG483_008465	COG1510	regulation of RNA biosynthetic process
CG483_008475	COG1454	alcohol dehydrogenase
CG483_008490	COG1012	belongs to the aldehyde dehydrogenase family
CG483_008505	COG0628	permease
CG483_008510	COG0039	L-malate dehydrogenase activity
CG483_008515	COG0523	cobalamin synthesis protein
CG483_008540	COG1686	Belongs to the peptidase S11 family
CG483_008555	COG0791	NLP P60 protein
CG483_008555	COG1388	LysM domain
CG483_008560	COG0300	oxidoreductase activity
CG483_008570	COG0460	homoserine dehydrogenase
CG483_008580	COG0083	homoserine kinase activity
CG483_008585	COG1316	TRANSCRIPTIONal
CG483_008590	COG0726	polysaccharide deacetylase
CG483_008600	COG1285	pathogenesis
CG483_008605	COG1247	-acetyltransferase
CG483_008620	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG483_008640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CG483_008645	COG0577	efflux transmembrane transporter activity
CG483_008650	COG2409	Drug exporters of the RND superfamily
CG483_008655	COG1404	Belongs to the peptidase S8 family
CG483_008670	COG0840	transmembrane signaling receptor activity
CG483_008685	COG3949	Membrane
CG483_008690	COG0783	Belongs to the Dps family
CG483_008710	COG0523	cobalamin synthesis protein
CG483_008720	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG483_008735	COG1902	pentaerythritol trinitrate reductase activity
CG483_008740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG483_008750	COG4166	transmembrane transport
CG483_008755	COG0346	lactoylglutathione lyase activity
CG483_008765	COG5337	Spore coat protein CotH
CG483_008770	COG1051	belongs to the nudix hydrolase family
CG483_008775	COG0586	Pfam SNARE associated Golgi protein
CG483_008780	COG2244	polysaccharide biosynthetic process
CG483_008790	COG0701	Predicted permease
CG483_008795	COG3689	TIGRFAM TIGR03943 family protein
CG483_008800	COG1607	acyl-coa hydrolase
CG483_008810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG483_008820	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_008830	COG2839	Protein conserved in bacteria
CG483_008835	COG1253	flavin adenine dinucleotide binding
CG483_008850	COG1114	Component of the transport system for branched-chain amino acids
CG483_008875	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG483_008885	COG1876	peptidase activity
CG483_008935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG483_008940	COG1819	glycosyl
CG483_008945	COG1819	glycosyl
CG483_008950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG483_009000	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG483_009055	COG3874	Sporulation protein YtfJ
CG483_009080	COG2226	methyltransferase
CG483_009105	COG0386	Belongs to the glutathione peroxidase family
CG483_009140	COG0640	Transcriptional regulator
CG483_009145	COG0798	PFAM Bile acid sodium symporter
CG483_009150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG483_009195	COG1418	mRNA catabolic process
CG483_009200	COG0488	(ABC) transporter
CG483_009210	COG0629	single-stranded DNA binding
CG483_009215	COG1413	lyase activity
CG483_009230	COG2136	Putative SAM-dependent methyltransferase
CG483_009230	COG2521	methyltransferase
CG483_009235	COG0018	arginyl-trna synthetase
CG483_009245	COG0733	neurotransmitter:sodium symporter activity
CG483_009270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG483_009275	COG0477	Major facilitator Superfamily
CG483_009295	COG2610	gluconate transmembrane transporter activity
CG483_009305	COG0456	acetyltransferase
CG483_009310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG483_009320	COG1131	(ABC) transporter
CG483_009325	COG4473	ABC transporter
CG483_009340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG483_009345	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG483_009355	COG0768	penicillin binding
CG483_009365	COG0204	Acyl-transferase
CG483_009370	COG1272	protein, Hemolysin III
CG483_009375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG483_009380	COG0805	protein transport
CG483_009390	COG1307	EDD domain protein, DegV family
CG483_009400	COG1999	signal sequence binding
CG483_009405	COG0071	Belongs to the small heat shock protein (HSP20) family
CG483_009410	COG0367	asparagine synthase
CG483_009425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG483_009445	COG0071	Belongs to the small heat shock protein (HSP20) family
CG483_009455	COG1737	Transcriptional regulator
CG483_009460	COG1070	Carbohydrate kinase
CG483_009470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CG483_009525	COG1151	hydroxylamine reductase activity
CG483_009535	COG1253	flavin adenine dinucleotide binding
CG483_009540	COG5506	Protein of unknown function (DUF1694)
CG483_009560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG483_009565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CG483_009570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG483_009575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG483_009585	COG3829	transcription factor binding
CG483_009595	COG1509	lysine 2,3-aminomutase activity
CG483_009605	COG4479	Belongs to the UPF0346 family
CG483_009630	COG1357	PFAM Pentapeptide repeats (8 copies)
CG483_009630	COG0515	serine threonine protein kinase
CG483_009635	COG0671	phosphoesterase, PA-phosphatase related
CG483_009640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG483_009645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG483_009690	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CG483_009700	COG0726	polysaccharide deacetylase
CG483_009705	COG1408	metallophosphoesterase
CG483_009710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG483_009715	COG2323	membrane
CG483_009720	COG0671	phosphoesterase, PA-phosphatase related
CG483_009730	COG1280	lysine exporter protein (LysE YggA)
CG483_009735	COG3403	YqcI/YcgG family
CG483_009765	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG483_009765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG483_009775	COG0372	Belongs to the citrate synthase family
CG483_009780	COG2079	MmgE PrpD family protein
CG483_009785	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CG483_009790	COG1960	acyl-CoA dehydrogenase activity
CG483_009795	COG2084	Dehydrogenase
CG483_009800	COG1012	belongs to the aldehyde dehydrogenase family
CG483_009810	COG1280	lysine exporter protein (LysE YggA)
CG483_009830	COG0420	3'-5' exonuclease activity
CG483_009835	COG0419	ATPase involved in DNA repair
CG483_009840	COG3104	oligopeptide transport
CG483_009875	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CG483_009880	COG1131	(ABC) transporter
CG483_009900	COG1131	(ABC) transporter
CG483_009905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG483_009925	COG1942	4-Oxalocrotonate Tautomerase
CG483_009960	COG0457	Tetratricopeptide repeat
CG483_009995	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_010000	COG1169	isochorismate synthase
CG483_010005	COG1021	2,3-dihydroxybenzoate-AMP ligase
CG483_010010	COG1535	isochorismatase
CG483_010010	COG3433	isochorismatase activity
CG483_010015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG483_010020	COG3251	PFAM MbtH domain protein
CG483_010025	COG2814	Major facilitator Superfamily
CG483_010040	COG0776	regulation of translation
CG483_010055	COG2329	Antibiotic biosynthesis monooxygenase
CG483_010060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG483_010095	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CG483_010105	COG0667	Aldo Keto reductase
CG483_010125	COG0010	Belongs to the arginase family
CG483_010135	COG1132	(ABC) transporter
CG483_010140	COG1132	(ABC) transporter
CG483_010145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG483_010170	COG1649	PFAM Uncharacterised BCR, COG1649
CG483_010190	COG2971	BadF BadG BcrA BcrD
CG483_010210	COG0588	phosphoglycerate mutase activity
CG483_010240	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG483_010250	COG1960	acyl-CoA dehydrogenase activity
CG483_010255	COG0439	Biotin carboxylase
CG483_010260	COG0511	ligase activity, forming carbon-carbon bonds
CG483_010265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG483_010270	COG1024	Enoyl-CoA hydratase
CG483_010275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG483_010280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG483_010290	COG1216	Glycosyl transferase, family 2
CG483_010295	COG0640	Transcriptional regulator
CG483_010305	COG1686	Belongs to the peptidase S11 family
CG483_010310	COG5002	protein histidine kinase activity
CG483_010340	COG0789	Transcriptional regulator
CG483_010360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG483_010370	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_010390	COG0475	glutathione-regulated potassium exporter activity
CG483_010410	COG1309	transcriptional regulator
CG483_010420	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_010425	COG2002	toxin-antitoxin pair type II binding
CG483_010430	COG3409	Peptidoglycan-binding domain 1 protein
CG483_010430	COG3773	Cell wall hydrolase
CG483_010445	COG0693	protein deglycase activity
CG483_010450	COG0201	protein transport
CG483_010470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG483_010475	COG0322	excinuclease ABC activity
CG483_010490	COG4667	esterase of the alpha-beta hydrolase superfamily
CG483_010510	COG1051	belongs to the nudix hydrolase family
CG483_010560	COG2223	nitrite transmembrane transporter activity
CG483_010610	COG1216	Glycosyl transferase, family 2
CG483_010625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG483_010630	COG1279	arginine transmembrane transporter activity
CG483_010670	COG1794	racemase activity, acting on amino acids and derivatives
CG483_010680	COG2828	Protein conserved in bacteria
CG483_010685	COG5002	protein histidine kinase activity
CG483_010690	COG0561	phosphatase activity
CG483_010710	COG2124	cytochrome p450
CG483_010745	COG0457	Tetratricopeptide repeat
CG483_010755	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG483_010785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG483_010790	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG483_010800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG483_010810	COG2959	enzyme of heme biosynthesis
CG483_010815	COG3409	Peptidoglycan-binding domain 1 protein
CG483_010815	COG3773	Cell wall hydrolase
CG483_010840	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CG483_010845	COG3844	kynureninase activity
CG483_010855	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_010865	COG4176	ABC-type proline glycine betaine transport system permease component
CG483_010870	COG0517	IMP dehydrogenase activity
CG483_010870	COG4175	Glycine betaine
CG483_010900	COG2153	protein acetylation
CG483_010930	COG0514	ATP-dependent DNA helicase (RecQ)
CG483_010950	COG4637	Psort location Cytoplasmic, score
CG483_010955	COG1227	inorganic diphosphatase activity
CG483_010965	COG3397	chitin binding
CG483_011005	COG4166	transmembrane transport
CG483_011015	COG4948	Mandelate Racemase Muconate Lactonizing
CG483_011095	COG1307	EDD domain protein, DegV family
CG483_011145	COG5444	nuclease activity
CG483_011255	COG5444	nuclease activity
CG483_011275	COG2261	transglycosylase associated protein
CG483_011280	COG0675	Transposase, IS605 OrfB family
CG483_011305	COG0436	Aminotransferase
CG483_011320	COG3973	AAA domain
CG483_011325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG483_011350	COG0628	permease
CG483_011365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG483_011370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG483_011375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG483_011390	COG2746	aminoglycoside 3-N-acetyltransferase activity
CG483_011405	COG0454	-acetyltransferase
CG483_011405	COG0456	acetyltransferase
CG483_011415	COG0726	polysaccharide deacetylase
CG483_011420	COG3037	sugar-specific permease SgaT UlaA
CG483_011430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG483_011435	COG1368	sulfuric ester hydrolase activity
CG483_011440	COG0488	(ABC) transporter
CG483_011445	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG483_011445	COG1605	Chorismate mutase
CG483_011465	COG0346	lactoylglutathione lyase activity
CG483_011475	COG3547	Transposase (IS116 IS110 IS902 family)
CG483_011480	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG483_011520	COG2329	Antibiotic biosynthesis monooxygenase
CG483_011535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG483_011560	COG0494	nUDIX hydrolase
CG483_011575	COG0456	acetyltransferase
CG483_011580	COG0477	Major facilitator Superfamily
CG483_011595	COG0697	spore germination
CG483_011600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG483_011610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG483_011625	COG0730	response to heat
CG483_011635	COG0833	amino acid
CG483_011660	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CG483_011675	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CG483_011680	COG1984	allophanate hydrolase subunit 2
CG483_011685	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG483_011690	COG1414	Transcriptional regulator
CG483_011705	COG1960	acyl-CoA dehydrogenase activity
CG483_011735	COG0346	lactoylglutathione lyase activity
CG483_011745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG483_011750	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG483_011755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG483_011760	COG0438	transferase activity, transferring glycosyl groups
CG483_011775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG483_011780	COG0438	transferase activity, transferring glycosyl groups
CG483_011785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG483_011795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG483_011815	COG4851	CamS sex pheromone cAM373 precursor
CG483_011935	COG0477	Major facilitator Superfamily
CG483_011950	COG1846	Transcriptional regulator
CG483_011955	COG2814	Major facilitator Superfamily
CG483_011965	COG2031	fatty acid transporter
CG483_012000	COG1122	ATPase activity
CG483_012025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG483_012040	COG1131	(ABC) transporter
CG483_012100	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CG483_012105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG483_012110	COG0579	oxidoreductase
CG483_012115	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CG483_012125	COG1253	flavin adenine dinucleotide binding
CG483_012130	COG0789	Transcriptional regulator
CG483_012135	COG3813	Protein conserved in bacteria
CG483_012215	COG0582	viral genome integration into host DNA
CG483_012255	COG4591	ABC-type transport system involved in lipoprotein release permease component
CG483_012260	COG1136	(ABC) transporter
CG483_012260	COG0577	efflux transmembrane transporter activity
CG483_012325	COG2072	flavoprotein involved in K transport
CG483_012350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG483_012355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG483_012370	COG1193	negative regulation of DNA recombination
CG483_012375	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CG483_012380	COG1164	Oligoendopeptidase f
CG483_012400	COG0584	glycerophosphoryl diester phosphodiesterase
CG483_012405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG483_012435	COG3397	chitin binding
CG483_012445	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG483_012450	COG0277	FAD linked oxidase domain protein
CG483_012455	COG1285	pathogenesis
CG483_012460	COG2720	vancomycin resistance protein
CG483_012660	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CG483_012765	COG1484	DNA-dependent DNA replication
CG483_012815	COG0582	viral genome integration into host DNA
CG483_012840	COG1278	Cold shock
CG483_012850	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_012855	COG0165	Argininosuccinate lyase
CG483_012870	COG3409	Peptidoglycan-binding domain 1 protein
CG483_012885	COG4145	pantothenate transmembrane transporter activity
CG483_012890	COG3924	membrane
CG483_012895	COG1012	belongs to the aldehyde dehydrogenase family
CG483_012905	COG1657	PFAM Prenyltransferase squalene oxidase
CG483_012910	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CG483_012915	COG2962	Rard protein
CG483_012950	COG2226	methyltransferase
CG483_012955	COG4166	transmembrane transport
CG483_012960	COG4166	transmembrane transport
CG483_012965	COG1301	dicarboxylic acid transport
CG483_012970	COG0673	inositol 2-dehydrogenase activity
CG483_012975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG483_012980	COG0187	DNA topoisomerase II activity
CG483_012990	COG1832	CoA-binding protein
CG483_012995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG483_013000	COG0745	RESPONSE REGULATOR receiver
CG483_013015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG483_013020	COG4841	protein insertion into membrane
CG483_013030	COG0824	Thioesterase
CG483_013060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG483_013065	COG3655	Transcriptional regulator
CG483_013085	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG483_013095	COG0726	polysaccharide deacetylase
CG483_013125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG483_013130	COG0318	PFAM AMP-dependent synthetase and ligase
CG483_013160	COG0457	Tetratricopeptide repeat
CG483_013235	COG2826	transposase and inactivated derivatives, IS30 family
CG483_013250	COG0534	Mate efflux family protein
CG483_013280	COG3023	N-Acetylmuramoyl-L-alanine amidase
CG483_013290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG483_013300	COG5002	protein histidine kinase activity
CG483_013305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG483_013310	COG0010	Belongs to the arginase family
CG483_013315	COG1228	amidohydrolase
CG483_013320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CG483_013325	COG2986	histidine ammonia-lyase
CG483_013345	COG4846	Membrane protein involved in cytochrome C biogenesis
CG483_013350	COG0785	Cytochrome C biogenesis protein
CG483_013365	COG0583	DNA-binding transcription factor activity
CG483_013370	COG1380	Effector of murein hydrolase LrgA
CG483_013375	COG1346	cytolysis
CG483_013380	COG4187	Peptidase family M20/M25/M40
CG483_013390	COG0833	amino acid
CG483_013400	COG0730	response to heat
CG483_013410	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG483_013410	COG3409	Peptidoglycan-binding domain 1 protein
CG483_013425	COG1132	(ABC) transporter
CG483_013430	COG1132	(ABC) transporter
CG483_013435	COG3763	UPF0154 protein
CG483_013450	COG3639	organic phosphonate transmembrane transporter activity
CG483_013455	COG3639	organic phosphonate transmembrane transporter activity
CG483_013470	COG0737	Belongs to the 5'-nucleotidase family
CG483_013475	COG4224	UPF0291 protein
CG483_013480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG483_013485	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CG483_013500	COG1695	Transcriptional regulator
CG483_013535	COG3328	transposase activity
CG483_013540	COG3328	transposase activity
CG483_013545	COG3328	transposase activity
CG483_013560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG483_013605	COG0730	response to heat
CG483_013660	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG483_013730	COG3723	Recombinational DNA repair protein, rece pathway
CG483_013775	COG0582	viral genome integration into host DNA
CG483_013780	COG0174	glutamine synthetase
CG483_013785	COG0789	Transcriptional regulator
CG483_013790	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CG483_013795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG483_013800	COG2860	membrane
CG483_013805	COG0464	growth
CG483_013820	COG1923	regulation of RNA biosynthetic process
CG483_013825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG483_013835	COG1388	LysM domain
CG483_013835	COG3584	3D domain protein
CG483_013840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG483_013840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG483_013840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG483_013845	COG1105	Belongs to the carbohydrate kinase PfkB family
CG483_013850	COG1349	DNA-binding transcription factor activity
CG483_013855	COG2322	membrane
CG483_013880	COG2116	formate transmembrane transporter activity
CG483_013890	COG1937	Protein conserved in bacteria
CG483_013895	COG2819	hydrolase of the alpha beta superfamily
CG483_013900	COG1120	ATPase activity
CG483_013905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG483_013910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG483_013915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG483_013920	COG2706	6-phosphogluconolactonase activity
CG483_013925	COG2826	transposase and inactivated derivatives, IS30 family
CG483_013930	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG483_013940	COG0346	lactoylglutathione lyase activity
CG483_013955	COG1113	amino acid transport
CG483_013980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG483_013985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG483_013995	COG4550	Control of competence regulator ComK, YlbF/YmcA
CG483_014000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG483_014005	COG1013	pyruvate-flavodoxin oxidoreductase activity
CG483_014010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CG483_014010	COG0674	pyruvate-flavodoxin oxidoreductase activity
CG483_014020	COG2359	stage V sporulation protein S
CG483_014025	COG1692	metallophosphoesterase
CG483_014030	COG1418	mRNA catabolic process
CG483_014035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG483_014040	COG1058	Belongs to the CinA family
CG483_014040	COG1546	Belongs to the CinA family
CG483_014045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG483_014050	COG1426	Protein conserved in bacteria
CG483_014065	COG0300	oxidoreductase activity
CG483_014070	COG0612	Peptidase, M16
CG483_014075	COG0612	Peptidase, M16
CG483_014100	COG2188	Transcriptional regulator
CG483_014120	COG0740	serine-type endopeptidase activity
CG483_014145	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG483_014160	COG0527	aspartate kinase activity
CG483_014165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG483_014170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG483_014175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG483_014180	COG1873	PFAM PRC-barrel domain
CG483_014185	COG0612	Peptidase, M16
CG483_014190	COG0726	polysaccharide deacetylase
CG483_014195	COG1185	polyribonucleotide nucleotidyltransferase activity
CG483_014205	COG0196	riboflavin kinase activity
CG483_014210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG483_014215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CG483_014220	COG1550	Protein conserved in bacteria
CG483_014225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CG483_014230	COG1358	cellular component organization or biogenesis
CG483_014235	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CG483_014240	COG0195	Participates in both transcription termination and antitermination
CG483_014245	COG0779	Required for maturation of 30S ribosomal subunits
CG483_014255	COG0442	prolyl-tRNA aminoacylation
CG483_014260	COG0750	zinc metalloprotease
CG483_014270	COG4589	Belongs to the CDS family
CG483_014280	COG0233	cytoplasmic translational termination
CG483_014285	COG0528	UMP kinase activity
CG483_014290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG483_014295	COG0052	Belongs to the universal ribosomal protein uS2 family
CG483_014300	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CG483_014305	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CG483_014315	COG4974	Belongs to the 'phage' integrase family
CG483_014320	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CG483_014325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG483_014330	COG0758	DNA mediated transformation
CG483_014335	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CG483_014340	COG0045	succinate-CoA ligase (ADP-forming) activity
CG483_014345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG483_014360	COG0335	large ribosomal subunit rRNA binding
CG483_014370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CG483_014375	COG1837	Belongs to the UPF0109 family
CG483_014380	COG0228	four-way junction DNA binding
CG483_014385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG483_014390	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CG483_014395	COG0552	protein localization to endoplasmic reticulum
CG483_014400	COG1196	nuclear chromosome segregation
CG483_014405	COG0571	ribonuclease III activity
CG483_014415	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_014420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CG483_014425	COG0416	fatty acid biosynthetic process
CG483_014430	COG1349	DNA-binding transcription factor activity
CG483_014430	COG2050	protein possibly involved in aromatic compounds catabolism
CG483_014435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG483_014440	COG1461	Dihydroxyacetone kinase
CG483_014445	COG1302	Protein conserved in bacteria
CG483_014450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CG483_014460	COG1564	THIamine pyrophosphokinase
CG483_014465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CG483_014470	COG1162	GTPase activity
CG483_014475	COG2815	serine threonine protein kinase
CG483_014475	COG0515	serine threonine protein kinase
CG483_014480	COG0631	protein serine/threonine phosphatase activity
CG483_014485	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG483_014490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG483_014490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG483_014495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG483_014500	COG0242	peptide deformylase activity
CG483_014505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG483_014510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG483_014515	COG1758	RNA polymerase activity
CG483_014520	COG0194	GDP metabolic process
CG483_014530	COG1561	YicC-like family, N-terminal region
CG483_014535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG483_014560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CG483_014570	COG0167	dihydroorotate dehydrogenase activity
CG483_014575	COG0543	2 iron, 2 sulfur cluster binding
CG483_014580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CG483_014590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CG483_014595	COG0540	Belongs to the ATCase OTCase family
CG483_014605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CG483_014615	COG0564	pseudouridine synthase activity
CG483_014620	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG483_014630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CG483_014635	COG3599	regulation of cell shape
CG483_014640	COG2302	S4 RNA-binding domain
CG483_014645	COG0762	integral membrane protein
CG483_014650	COG1799	cell septum assembly
CG483_014655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CG483_014665	COG1873	PFAM PRC-barrel domain
CG483_014670	COG1191	sigma factor activity
CG483_014675	COG1191	sigma factor activity
CG483_014685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG483_014690	COG0849	cell division
CG483_014695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG483_014705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG483_014710	COG0772	Belongs to the SEDS family
CG483_014715	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG483_014720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG483_014725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG483_014730	COG0768	penicillin binding
CG483_014740	COG4839	cell division protein FtsL
CG483_014745	COG0275	rRNA processing
CG483_014750	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CG483_014755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CG483_014775	COG1399	metal-binding, possibly nucleic acid-binding protein
CG483_014885	COG4626	Terminase
CG483_014885	COG1802	Transcriptional regulator
CG483_014975	COG0756	dUTP diphosphatase activity
CG483_015005	COG3723	Recombinational DNA repair protein, rece pathway
CG483_015015	COG5377	YqaJ viral recombinase family
CG483_015060	COG0582	viral genome integration into host DNA
CG483_015065	COG1323	Belongs to the UPF0348 family
CG483_015070	COG3480	Lon protease (S16) C-terminal proteolytic domain
CG483_015075	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG483_015080	COG3314	Sporulation integral membrane protein YlbJ
CG483_015085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG483_015090	COG0742	ribosomal rna small subunit methyltransferase
CG483_015100	COG4471	UPF0298 protein
CG483_015105	COG3679	Belongs to the UPF0342 family
CG483_015110	COG0406	alpha-ribazole phosphatase activity
CG483_015125	COG2340	Cysteine-rich secretory protein family
CG483_015135	COG3336	cytochrome c oxidase
CG483_015160	COG0109	protoheme IX farnesyltransferase activity
CG483_015165	COG1612	heme a metabolic process
CG483_015170	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CG483_015180	COG0772	Belongs to the SEDS family
CG483_015185	COG4838	Belongs to the UPF0358 family
CG483_015190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CG483_015195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CG483_015205	COG4896	Protein conserved in bacteria
CG483_015230	COG0483	inositol monophosphate 1-phosphatase activity
CG483_015240	COG4493	Belongs to the UPF0637 family
CG483_015245	COG4476	Belongs to the UPF0223 family
CG483_015250	COG1982	Orn Lys Arg decarboxylase major
CG483_015290	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG483_015300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG483_015315	COG0561	phosphatase activity
CG483_015330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG483_015335	COG0569	domain protein
CG483_015345	COG1473	amidohydrolase
CG483_015350	COG2171	N-acyltransferase activity
CG483_015355	COG0583	DNA-binding transcription factor activity
CG483_015360	COG0517	IMP dehydrogenase activity
CG483_015370	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CG483_015390	COG4703	Protein of unknown function (DUF1797)
CG483_015405	COG2200	EAL domain
CG483_015410	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_015415	COG1408	metallophosphoesterase
CG483_015425	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CG483_015465	COG2814	Major facilitator Superfamily
CG483_015470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG483_015480	COG3209	COG3209 Rhs family protein
CG483_015490	COG2205	protein histidine kinase activity
CG483_015500	COG0436	Aminotransferase
CG483_015505	COG1609	Transcriptional regulator
CG483_015510	COG3833	ABC-type maltose transport systems, permease component
CG483_015515	COG1175	transmembrane transport
CG483_015520	COG2182	Extracellular solute-binding protein
CG483_015535	COG0366	Alpha amylase catalytic
CG483_015540	COG3842	ATPase activity
CG483_015570	COG0183	Belongs to the thiolase family
CG483_015600	COG1695	Transcriptional regulator
CG483_015605	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_015615	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CG483_015620	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CG483_015625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG483_015630	COG0436	Aminotransferase
CG483_015635	COG1850	ribulose-bisphosphate carboxylase activity
CG483_015640	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CG483_015645	COG0235	Class ii aldolase
CG483_015650	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CG483_015665	COG2084	Dehydrogenase
CG483_015680	COG0778	Nitroreductase
CG483_015705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG483_015705	COG2190	(PTS) system
CG483_015705	COG1263	PTS System
CG483_015710	COG3711	transcriptional antiterminator
CG483_015725	COG0363	glucosamine-6-phosphate deaminase activity
CG483_015740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG483_015745	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG483_015755	COG1547	Domain of unknown function (DUF309)
CG483_015765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CG483_015770	COG4086	secreted protein
CG483_015775	COG0561	phosphatase activity
CG483_015780	COG0697	spore germination
CG483_015795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG483_015820	COG0733	neurotransmitter:sodium symporter activity
CG483_015830	COG2172	sigma factor antagonist activity
CG483_015840	COG1686	Belongs to the peptidase S11 family
CG483_015850	COG1725	Transcriptional regulator
CG483_015855	COG1131	(ABC) transporter
CG483_015880	COG1846	Transcriptional regulator
CG483_015895	COG0598	Magnesium transport protein CorA
CG483_015925	COG4974	Belongs to the 'phage' integrase family
CG483_015935	COG0735	belongs to the Fur family
CG483_015940	COG1300	Membrane
CG483_015960	COG0667	Aldo Keto reductase
CG483_015965	COG0656	L-ascorbic acid biosynthetic process
CG483_015970	COG0456	acetyltransferase
CG483_015970	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CG483_015980	COG0737	Belongs to the 5'-nucleotidase family
CG483_015980	COG1525	nuclease
CG483_015980	COG4085	toxin activity
CG483_015990	COG0596	Alpha beta hydrolase
CG483_015995	COG2056	Na+-H+ antiporter family
CG483_016000	COG1609	Transcriptional regulator
CG483_016005	COG0456	acetyltransferase
CG483_016010	COG1073	alpha beta
CG483_016025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG483_016025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG483_016030	COG0307	riboflavin synthase, alpha
CG483_016035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG483_016035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG483_016050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG483_016055	COG4106	trans-aconitate 2-methyltransferase activity
CG483_016060	COG0596	Alpha beta hydrolase
CG483_016065	COG0156	8-amino-7-oxononanoate synthase activity
CG483_016075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG483_016090	COG0737	Belongs to the 5'-nucleotidase family
CG483_016115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG483_016125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG483_016135	COG0300	oxidoreductase activity
CG483_016140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG483_016145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG483_016150	COG1760	l-serine dehydratase
CG483_016155	COG1760	l-serine dehydratase
CG483_016165	COG1234	tRNA 3'-trailer cleavage
CG483_016185	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG483_016190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG483_016205	COG1376	ErfK ybiS ycfS ynhG family protein
CG483_016210	COG4129	membrane
CG483_016215	COG1126	abc transporter atp-binding protein
CG483_016220	COG0765	amino acid transport
CG483_016225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG483_016240	COG2816	NAD+ diphosphatase activity
CG483_016245	COG0772	Belongs to the SEDS family
CG483_016255	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG483_016260	COG0022	dehydrogenase e1 component
CG483_016265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG483_016270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG483_016275	COG3426	butyrate kinase activity
CG483_016280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG483_016285	COG0280	phosphate acetyltransferase
CG483_016295	COG3829	transcription factor binding
CG483_016295	COG3290	protein histidine kinase activity
CG483_016305	COG0584	glycerophosphoryl diester phosphodiesterase
CG483_016310	COG3093	addiction module antidote protein HigA
CG483_016315	COG0745	RESPONSE REGULATOR receiver
CG483_016320	COG0750	zinc metalloprotease
CG483_016325	COG0497	DNA recombination
CG483_016335	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CG483_016340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG483_016350	COG1722	exodeoxyribonuclease VII activity
CG483_016355	COG1570	exodeoxyribonuclease VII activity
CG483_016360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG483_016365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG483_016370	COG1302	Protein conserved in bacteria
CG483_016375	COG0439	Biotin carboxylase
CG483_016380	COG0511	ligase activity, forming carbon-carbon bonds
CG483_016425	COG3854	ATPases associated with a variety of cellular activities
CG483_016445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG483_016450	COG0006	proline dipeptidase activity
CG483_016455	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG483_016465	COG3872	metal-dependent enzyme
CG483_016475	COG1321	iron dependent repressor
CG483_016490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG483_016500	COG1609	Transcriptional regulator
CG483_016510	COG2076	Multidrug Resistance protein
CG483_016515	COG2076	Multidrug Resistance protein
CG483_016540	COG1131	(ABC) transporter
CG483_016545	COG1725	Transcriptional regulator
CG483_016560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG483_016565	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG483_016570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG483_016575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG483_016605	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG483_016630	COG1459	type II secretion system
CG483_016635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG483_016670	COG1078	dGTPase activity
CG483_016690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CG483_016690	COG0646	methionine synthase
CG483_016695	COG0626	cystathionine gamma-synthase activity
CG483_016700	COG0626	cystathionine gamma-synthase activity
CG483_016720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG483_016730	COG1940	carbohydrate kinase activity
CG483_016735	COG4483	Protein conserved in bacteria
CG483_016740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CG483_016745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG483_016760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CG483_016765	COG0581	inorganic phosphate transmembrane transporter activity
CG483_016770	COG0573	inorganic phosphate transmembrane transporter activity
CG483_016775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG483_016785	COG0477	Major facilitator Superfamily
CG483_016790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG483_016810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG483_016815	COG0735	belongs to the Fur family
CG483_016820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG483_016825	COG1121	(ABC) transporter
CG483_016830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG483_016840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CG483_016860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CG483_016865	COG2384	SAM-dependent methyltransferase
CG483_016875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG483_016880	COG0358	DNA primase activity
CG483_016885	COG1671	Belongs to the UPF0178 family
CG483_016890	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CG483_016895	COG0517	IMP dehydrogenase activity
CG483_016900	COG1381	Involved in DNA repair and RecF pathway recombination
CG483_016910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG483_016920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG483_016925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CG483_016930	COG1480	7TM receptor with intracellular HD hydrolase
CG483_016935	COG1702	phosphate starvation-inducible protein PhoH
CG483_016950	COG1610	YqeY-like protein
CG483_016955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG483_016960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG483_016965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG483_016970	COG2264	protein methyltransferase activity
CG483_016975	COG0484	heat shock protein binding
CG483_016980	COG0443	Heat shock 70 kDa protein
CG483_016985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG483_016990	COG1420	regulation of RNA biosynthetic process
CG483_016995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG483_017000	COG1733	regulation of RNA biosynthetic process
CG483_017005	COG0693	protein deglycase activity
CG483_017010	COG0481	GTPase activity
CG483_017025	COG0268	Binds directly to 16S ribosomal RNA
CG483_017030	COG1466	dna polymerase III delta subunit
CG483_017040	COG0658	competence protein
CG483_017040	COG2333	competence protein COMEC
CG483_017045	COG2131	deaminase
CG483_017050	COG1555	photosystem II stabilization
CG483_017050	COG1596	polysaccharide export
CG483_017055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG483_017060	COG2226	methyltransferase
CG483_017065	COG0799	negative regulation of ribosome biogenesis
CG483_017070	COG1713	HD superfamily hydrolase involved in NAD metabolism
CG483_017075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG483_017080	COG1534	Rna-binding protein
CG483_017085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG483_017090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CG483_017095	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CG483_017105	COG0688	phosphatidylethanolamine metabolic process
CG483_017110	COG1191	sigma factor activity
CG483_017120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG483_017125	COG2357	RelA SpoT domain protein
CG483_017130	COG1785	Belongs to the alkaline phosphatase family
CG483_017135	COG0456	acetyltransferase
CG483_017140	COG2267	carboxylic ester hydrolase activity
CG483_017165	COG3186	Phenylalanine-4-hydroxylase
CG483_017170	COG2154	pterin-4-alpha-carbinolamine dehydratase
CG483_017175	COG2514	catechol 2,3-dioxygenase activity
CG483_017180	COG2259	Doxx family
CG483_017195	COG1609	Transcriptional regulator
CG483_017205	COG0626	cystathionine gamma-synthase activity
CG483_017210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG483_017215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CG483_017220	COG2226	methyltransferase
CG483_017235	COG0768	penicillin binding
CG483_017245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG483_017250	COG0572	uridine kinase
CG483_017270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG483_017280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG483_017285	COG4472	Bacterial protein of unknown function (DUF965)
CG483_017290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG483_017295	COG0628	permease
CG483_017315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CG483_017325	COG0482	sulfurtransferase activity
CG483_017330	COG1104	cysteine desulfurase activity
CG483_017335	COG1959	2 iron, 2 sulfur cluster binding
CG483_017340	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG483_017360	COG2207	Transcriptional regulator
CG483_017370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CG483_017375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG483_017380	COG0124	histidyl-tRNA synthetase
CG483_017400	COG1490	D-aminoacyl-tRNA deacylase activity
CG483_017405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG483_017410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG483_017415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG483_017415	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CG483_017420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG483_017425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG483_017425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG483_017435	COG2244	polysaccharide biosynthetic process
CG483_017460	COG1862	Preprotein translocase
CG483_017465	COG0343	queuine tRNA-ribosyltransferase activity
CG483_017470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG483_017480	COG2255	four-way junction helicase activity
CG483_017485	COG0632	four-way junction helicase activity
CG483_017490	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CG483_017510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CG483_017515	COG0157	Belongs to the NadC ModD family
CG483_017520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CG483_017525	COG1104	cysteine desulfurase activity
CG483_017530	COG1827	regulation of RNA biosynthetic process
CG483_017535	COG2258	MOSC domain
CG483_017540	COG0077	Prephenate dehydratase
CG483_017545	COG0577	efflux transmembrane transporter activity
CG483_017550	COG0577	efflux transmembrane transporter activity
CG483_017555	COG1136	(ABC) transporter
CG483_017560	COG5002	protein histidine kinase activity
CG483_017565	COG0745	RESPONSE REGULATOR receiver
CG483_017575	COG3290	protein histidine kinase activity
CG483_017580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG483_017585	COG2868	ribosomal protein
CG483_017595	COG1530	ribonuclease E activity
CG483_017600	COG1994	Peptidase M50
CG483_017605	COG0739	heme binding
CG483_017610	COG2894	cell division
CG483_017615	COG0850	regulation of cytokinetic process
CG483_017625	COG1792	Involved in formation and maintenance of cell shape
CG483_017630	COG1077	Cell shape determining protein MreB Mrl
CG483_017650	COG0424	maF-like protein
CG483_017660	COG0285	dihydrofolate synthase activity
CG483_017685	COG1388	LysM domain
CG483_017685	COG1388	LysM domain
CG483_017690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG483_017695	COG0113	porphobilinogen synthase activity
CG483_017700	COG1587	Uroporphyrinogen-III synthase
CG483_017705	COG0181	hydroxymethylbilane synthase activity
CG483_017710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG483_017715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CG483_017720	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG483_017730	COG0470	DNA polymerase III
CG483_017730	COG1067	ATP-dependent peptidase activity
CG483_017735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CG483_017740	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG483_017765	COG4221	oxidoreductase activity
CG483_017765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG483_017765	COG3321	synthase
CG483_017765	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_017780	COG2409	Drug exporters of the RND superfamily
CG483_017780	COG1033	growth of symbiont in host cell
CG483_017790	COG1309	transcriptional regulator
CG483_017850	COG0622	Phosphoesterase
CG483_017860	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG483_017865	COG5401	PFAM Sporulation and spore germination
CG483_017875	COG2197	response regulator
CG483_017885	COG1959	2 iron, 2 sulfur cluster binding
CG483_017890	COG1668	transmembrane transport
CG483_017895	COG4152	abc transporter atp-binding protein
CG483_017900	COG1360	Flagellar Motor Protein
CG483_017905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG483_017915	COG1876	peptidase activity
CG483_017925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CG483_017930	COG1053	succinate dehydrogenase
CG483_017935	COG2009	succinate dehydrogenase
CG483_017940	COG1719	4-vinyl reductase, 4VR
CG483_017955	COG3118	belongs to the thioredoxin family
CG483_017960	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CG483_017965	COG2086	electron transfer activity
CG483_017970	COG1024	Enoyl-CoA hydratase
CG483_017975	COG1309	transcriptional regulator
CG483_017980	COG0318	PFAM AMP-dependent synthetase and ligase
CG483_017990	COG2318	DinB family
CG483_018010	COG1131	(ABC) transporter
CG483_018015	COG2205	protein histidine kinase activity
CG483_018020	COG0745	RESPONSE REGULATOR receiver
CG483_018030	COG4895	conserved protein (DUF2196)
CG483_018040	COG1114	Component of the transport system for branched-chain amino acids
CG483_018045	COG1187	pseudouridine synthase activity
CG483_018055	COG1193	negative regulation of DNA recombination
CG483_018060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CG483_018060	COG1796	DNA polymerase
CG483_018065	COG1286	toxin biosynthetic process
CG483_018070	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CG483_018095	COG0017	Asparaginyl-tRNA synthetase
CG483_018100	COG0072	phenylalanine-tRNA ligase activity
CG483_018100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG483_018105	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CG483_018110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG483_018120	COG1418	mRNA catabolic process
CG483_018135	COG2814	Major facilitator Superfamily
CG483_018140	COG1566	PFAM secretion protein HlyD family protein
CG483_018145	COG1309	transcriptional regulator
CG483_018150	COG1363	Peptidase, m42
CG483_018160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CG483_018165	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CG483_018170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CG483_018175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG483_018185	COG1484	DNA-dependent DNA replication
CG483_018190	COG3611	Membrane attachment protein
CG483_018195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG483_018200	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CG483_018210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG483_018220	COG1971	Probably functions as a manganese efflux pump
CG483_018230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG483_018230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG483_018235	COG5002	protein histidine kinase activity
CG483_018240	COG0745	RESPONSE REGULATOR receiver
CG483_018250	COG0039	L-malate dehydrogenase activity
CG483_018255	COG0538	isocitrate dehydrogenase activity
CG483_018260	COG0372	Belongs to the citrate synthase family
CG483_018265	COG2707	UPF0756 membrane protein
CG483_018270	COG0628	permease
CG483_018275	COG3030	protein affecting phage T7 exclusion by the F plasmid
CG483_018285	COG0205	6-phosphofructokinase activity
CG483_018290	COG0825	malonyl-CoA metabolic process
CG483_018295	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CG483_018300	COG1725	Transcriptional regulator
CG483_018305	COG0281	malic enzyme
CG483_018310	COG0587	DNA-directed DNA polymerase activity
CG483_018325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CG483_018335	COG4109	DRTGG domain
CG483_018340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CG483_018345	COG0006	proline dipeptidase activity
CG483_018370	COG1028	Short-chain dehydrogenase reductase Sdr
CG483_018375	COG0589	response to stress
CG483_018400	COG0165	Argininosuccinate lyase
CG483_018405	COG0137	argininosuccinate synthase activity
CG483_018415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG483_018425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CG483_018430	COG0827	DNA restriction-modification system
CG483_018435	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CG483_018440	COG3874	Sporulation protein YtfJ
CG483_018450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CG483_018455	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CG483_018460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG483_018470	COG0301	tRNA thio-modification
CG483_018475	COG1104	cysteine desulfurase activity
CG483_018480	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CG483_018485	COG0583	DNA-binding transcription factor activity
CG483_018490	COG0697	spore germination
CG483_018495	COG1309	transcriptional regulator
CG483_018500	COG1956	GAF domain-containing protein
CG483_018505	COG0626	cystathionine gamma-synthase activity
CG483_018515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG483_018540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CG483_018550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG483_018555	COG0454	-acetyltransferase
CG483_018560	COG0517	IMP dehydrogenase activity
CG483_018565	COG0123	including yeast histone deacetylase and acetoin utilization protein
CG483_018570	COG1970	mechanosensitive ion channel activity
CG483_018580	COG1609	Transcriptional regulator
CG483_018590	COG1605	Chorismate mutase
CG483_018590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG483_018595	COG3118	belongs to the thioredoxin family
CG483_018605	COG2309	aminopeptidase activity
CG483_018620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG483_018630	COG1674	ftsk spoiiie
CG483_018640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG483_018645	COG4848	Belongs to the UPF0354 family
CG483_018650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG483_018655	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CG483_018675	COG1363	Peptidase, m42
CG483_018685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG483_018690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG483_018700	COG0510	thiamine kinase activity
CG483_018705	COG1523	belongs to the glycosyl hydrolase 13 family
CG483_018715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG483_018720	COG1349	DNA-binding transcription factor activity
CG483_018725	COG1187	pseudouridine synthase activity
CG483_018730	COG2244	polysaccharide biosynthetic process
CG483_018735	COG2081	HI0933 family
CG483_018740	COG2814	Major facilitator Superfamily
CG483_018750	COG3832	glyoxalase III activity
CG483_018770	COG1329	Transcriptional regulator
CG483_018780	COG2223	nitrite transmembrane transporter activity
CG483_018790	COG0314	molybdopterin synthase activity
CG483_018795	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG483_018800	COG0303	'Molybdopterin
CG483_018805	COG0315	cyclic pyranopterin monophosphate synthase activity
CG483_018810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG483_018815	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG483_018820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG483_018825	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CG483_018830	COG1140	nitrate reductase beta subunit
CG483_018835	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CG483_018840	COG2181	nitrate reductase activity
CG483_018855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG483_018865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG483_018900	COG0495	leucyl-tRNA aminoacylation
CG483_018905	COG2814	Major facilitator Superfamily
CG483_018915	COG1136	(ABC) transporter
CG483_018920	COG0346	lactoylglutathione lyase activity
CG483_018935	COG1242	4 iron, 4 sulfur cluster binding
CG483_018940	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CG483_018945	COG1121	(ABC) transporter
CG483_018955	COG1794	racemase activity, acting on amino acids and derivatives
CG483_018965	COG2378	regulation of single-species biofilm formation
CG483_018975	COG2267	carboxylic ester hydrolase activity
CG483_018990	COG0746	molybdenum cofactor guanylyltransferase activity
CG483_019015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG483_019025	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CG483_019075	COG0800	Aldolase
CG483_019080	COG2610	gluconate transmembrane transporter activity
CG483_019085	COG1312	Catalyzes the dehydration of D-mannonate
CG483_019095	COG1414	Transcriptional regulator
CG483_019100	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG483_019100	COG3409	Peptidoglycan-binding domain 1 protein
CG483_019110	COG1368	sulfuric ester hydrolase activity
CG483_019125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG483_019130	COG1116	anion transmembrane transporter activity
CG483_019135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG483_019150	COG0494	nUDIX hydrolase
CG483_019160	COG1854	S-ribosylhomocysteine lyase activity
CG483_019165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG483_019170	COG0288	reversible hydration of carbon dioxide
CG483_019175	COG1271	oxidase subunit
CG483_019180	COG1294	oxidase, subunit
CG483_019210	COG1842	Phage shock protein A
CG483_019255	COG1597	lipid kinase activity
CG483_019260	COG1136	(ABC) transporter
CG483_019270	COG0745	RESPONSE REGULATOR receiver
CG483_019275	COG2205	protein histidine kinase activity
CG483_019280	COG0577	efflux transmembrane transporter activity
CG483_019285	COG1136	(ABC) transporter
CG483_019305	COG4948	Mandelate Racemase Muconate Lactonizing
CG483_019310	COG0318	PFAM AMP-dependent synthetase and ligase
CG483_019315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG483_019320	COG0596	Alpha beta hydrolase
CG483_019325	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CG483_019330	COG1169	isochorismate synthase
CG483_019335	COG1575	Belongs to the MenA family. Type 1 subfamily
CG483_019340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CG483_019345	COG1278	Cold shock
CG483_019365	COG0058	SHG alpha-glucan phosphorylase activity
CG483_019370	COG0297	glycogen (starch) synthase activity
CG483_019375	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG483_019380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG483_019385	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG483_019390	COG0039	L-malate dehydrogenase activity
CG483_019485	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG483_019520	COG1285	pathogenesis
CG483_019525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG483_019535	COG0166	Belongs to the GPI family
CG483_019545	COG2155	Conserved Protein
CG483_019550	COG1098	S1 RNA binding domain
CG483_019555	COG0436	Aminotransferase
CG483_019560	COG1522	sequence-specific DNA binding
CG483_019565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG483_019570	COG2267	carboxylic ester hydrolase activity
CG483_019580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CG483_019585	COG2032	superoxide dismutase activity
CG483_019595	COG5018	Exonuclease
CG483_019600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG483_019605	COG0423	glycine-tRNA ligase activity
CG483_019625	COG2050	protein possibly involved in aromatic compounds catabolism
CG483_019635	COG1268	BioY protein
CG483_019640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG483_019645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG483_019655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG483_019665	COG3584	3D domain protein
CG483_019685	COG1252	NADH dehydrogenase
CG483_019690	COG0492	ferredoxin-NADP+ reductase activity
CG483_019705	COG1683	Conserved Protein
CG483_019740	COG1131	(ABC) transporter
CG483_019765	COG0316	Belongs to the HesB IscA family
CG483_019770	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CG483_019775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG483_019785	COG1252	NADH dehydrogenase
CG483_019790	COG2824	Alkylphosphonate utilization operon protein PhnA
CG483_019800	COG3655	Transcriptional regulator
CG483_019815	COG4837	Protein of unknown function (DUF1462)
CG483_019820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CG483_019825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG483_019830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CG483_019835	COG0647	UMP catabolic process
CG483_019845	COG2445	Protein of unknown function DUF86
CG483_019850	COG1494	fructose-1,6-bisphosphatase
CG483_019860	COG4470	Protein conserved in bacteria
CG483_019870	COG0789	Transcriptional regulator
CG483_019875	COG4377	Putative membrane peptidase family (DUF2324)
CG483_019890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CG483_019895	COG0739	heme binding
CG483_019905	COG3377	Domain of unknown function (DUF1805)
CG483_019910	COG0737	Belongs to the 5'-nucleotidase family
CG483_019930	COG0719	Fe-S assembly protein
CG483_019935	COG0822	iron-sulfur transferase activity
CG483_019940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG483_019945	COG0719	Fe-S assembly protein
CG483_019950	COG0396	ATPase activity
CG483_019955	COG1464	Belongs to the NlpA lipoprotein family
CG483_019960	COG2011	ABC-type metal ion transport system permease component
CG483_019975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG483_019980	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CG483_019990	COG0509	glycine decarboxylation via glycine cleavage system
CG483_019995	COG1393	Belongs to the ArsC family
CG483_020035	COG1960	acyl-CoA dehydrogenase activity
CG483_020040	COG0183	Belongs to the thiolase family
CG483_020045	COG1024	Enoyl-CoA hydratase
CG483_020045	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG483_020055	COG1686	Belongs to the peptidase S11 family
CG483_020080	COG0011	TIGRFAM Protein of
CG483_020085	COG0840	transmembrane signaling receptor activity
CG483_020105	COG0531	amino acid
CG483_020110	COG0706	membrane insertase activity
CG483_020120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG483_020130	COG0586	Pfam SNARE associated Golgi protein
CG483_020140	COG1376	ErfK ybiS ycfS ynhG family protein
CG483_020145	COG0745	RESPONSE REGULATOR receiver
CG483_020150	COG5002	protein histidine kinase activity
CG483_020155	COG0840	transmembrane signaling receptor activity
CG483_020160	COG0840	transmembrane signaling receptor activity
CG483_020165	COG2151	metal-sulfur cluster biosynthetic enzyme
CG483_020170	COG3227	Zinc metalloprotease (Elastase)
CG483_020175	COG1741	Belongs to the pirin family
CG483_020190	COG0783	Belongs to the Dps family
CG483_020195	COG1611	Belongs to the LOG family
CG483_020215	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG483_020220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG483_020225	COG1121	(ABC) transporter
CG483_020245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG483_020250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG483_020255	COG1115	amino acid carrier protein
CG483_020260	COG2910	NAD(P)H-binding
CG483_020275	COG1252	NADH dehydrogenase
CG483_020290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CG483_020305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG483_020310	COG4977	sequence-specific DNA binding
CG483_020310	COG1917	Cupin 2, conserved barrel domain protein
CG483_020315	COG3223	Belongs to the PsiE family
CG483_020320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CG483_020340	COG0697	spore germination
CG483_020355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CG483_020360	COG0557	exoribonuclease II activity
CG483_020365	COG1647	Serine aminopeptidase, S33
CG483_020370	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG483_020375	COG1346	cytolysis
CG483_020385	COG0148	phosphopyruvate hydratase activity
CG483_020390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CG483_020395	COG0149	triose-phosphate isomerase activity
CG483_020400	COG0126	phosphoglycerate kinase activity
CG483_020405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG483_020420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CG483_020470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG483_020485	COG2323	membrane
CG483_020495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG483_020500	COG1481	regulation of sporulation
CG483_020510	COG1660	Displays ATPase and GTPase activities
CG483_020515	COG1051	belongs to the nudix hydrolase family
CG483_020525	COG0492	ferredoxin-NADP+ reductase activity
CG483_020530	COG0457	Tetratricopeptide repeat
CG483_020535	COG0110	maltose O-acetyltransferase activity
CG483_020545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG483_020550	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CG483_020555	COG1950	PFAM Membrane protein of
CG483_020565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG483_020580	COG0789	Transcriptional regulator
CG483_020600	COG0583	DNA-binding transcription factor activity
CG483_020615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG483_020620	COG0793	Belongs to the peptidase S41A family
CG483_020620	COG3409	Peptidoglycan-binding domain 1 protein
CG483_020625	COG2177	Part of the ABC transporter FtsEX involved in
CG483_020630	COG2884	Cell division ATP-binding protein ftsE
CG483_020665	COG1278	Cold shock
CG483_020670	COG1040	competence protein
CG483_020675	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CG483_020680	COG0791	NLP P60 protein
CG483_020680	COG1388	LysM domain
CG483_020685	COG1733	regulation of RNA biosynthetic process
CG483_020690	COG1307	EDD domain protein, DegV family
CG483_020695	COG1739	Uncharacterized protein family UPF0029
CG483_020700	COG1316	TRANSCRIPTIONal
CG483_020710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CG483_020720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG483_020730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CG483_020730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CG483_020745	COG1486	melibiose metabolic process
CG483_020750	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG483_020765	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG483_020770	COG1301	dicarboxylic acid transport
CG483_020775	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CG483_020785	COG1271	oxidase subunit
CG483_020790	COG1294	oxidase, subunit
CG483_020795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CG483_020800	COG1620	l-lactate permease
CG483_020805	COG2389	metal-binding protein
CG483_020815	COG1368	sulfuric ester hydrolase activity
CG483_020825	COG1388	LysM domain
CG483_020825	COG0791	NLP P60 protein
CG483_020830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG483_020840	COG1215	transferase activity, transferring glycosyl groups
CG483_020850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG483_020855	COG1388	LysM domain
CG483_020855	COG3584	3D domain protein
CG483_020870	COG4715	Zinc finger, swim domain protein
CG483_020915	COG0577	efflux transmembrane transporter activity
CG483_020920	COG1136	(ABC) transporter
CG483_020955	COG3850	Histidine kinase
CG483_020955	COG5002	protein histidine kinase activity
CG483_020960	COG0745	RESPONSE REGULATOR receiver
CG483_020970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG483_020980	COG1215	transferase activity, transferring glycosyl groups
CG483_020980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG483_020985	COG1134	teichoic acid transport
CG483_020990	COG1682	transport, permease protein
CG483_020995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG483_021000	COG0463	Glycosyl transferase, family 2
CG483_021000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG483_021005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG483_021010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CG483_021025	COG1609	Transcriptional regulator
CG483_021035	COG0739	heme binding
CG483_021050	COG3279	Response regulator of the LytR AlgR family
CG483_021055	COG2385	sporulation resulting in formation of a cellular spore
CG483_021070	COG4836	Membrane
CG483_021075	COG1007	ATP synthesis coupled electron transport
CG483_021080	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG483_021085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG483_021090	COG0713	ATP synthesis coupled electron transport
CG483_021095	COG0839	Belongs to the complex I subunit 6 family
CG483_021105	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CG483_021110	COG0649	NAD binding
CG483_021115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG483_021120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG483_021125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG483_021130	COG5001	Diguanylate cyclase
CG483_021130	COG3300	MHYT domain
CG483_021135	COG5001	Diguanylate cyclase
CG483_021135	COG3300	MHYT domain
CG483_021150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG483_021155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG483_021165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG483_021170	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG483_021175	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG483_021180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG483_021185	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG483_021210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG483_021215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG483_021225	COG0698	ribose 5-phosphate isomerase
CG483_021245	COG2190	(PTS) system
CG483_021250	COG2259	Doxx family
CG483_021255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG483_021270	COG0009	L-threonylcarbamoyladenylate synthase
CG483_021285	COG2890	protein-(glutamine-N5) methyltransferase activity
CG483_021290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG483_021295	COG1435	thymidine kinase activity
CG483_021305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG483_021310	COG1494	fructose-1,6-bisphosphatase
CG483_021330	COG4821	SIS domain
CG483_021335	COG0504	CTP synthase activity
CG483_021350	COG1960	acyl-CoA dehydrogenase activity
CG483_021355	COG1960	acyl-CoA dehydrogenase activity
CG483_021360	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG483_021365	COG0183	Belongs to the thiolase family
CG483_021370	COG0247	lactate metabolic process
CG483_021370	COG2181	nitrate reductase activity
CG483_021375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG483_021390	COG2197	response regulator
CG483_021395	COG4585	Histidine kinase
CG483_021400	COG0842	Transport permease protein
CG483_021405	COG1131	(ABC) transporter
CG483_021410	COG0024	Methionine aminopeptidase
CG483_021415	COG2234	aminopeptidase activity
CG483_021430	COG4506	Protein conserved in bacteria
CG483_021435	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG483_021450	COG0010	Belongs to the arginase family
CG483_021455	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CG483_021460	COG2814	Major facilitator Superfamily
CG483_021465	COG0789	Transcriptional regulator
CG483_021470	COG0584	glycerophosphoryl diester phosphodiesterase
CG483_021475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG483_021485	COG1994	Peptidase M50
CG483_021495	COG1078	dGTPase activity
CG483_021500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG483_021505	COG1120	ATPase activity
CG483_021510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG483_021515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG483_021520	COG4844	belongs to the
CG483_021535	COG0280	phosphate acetyltransferase
CG483_021550	COG3773	Cell wall hydrolase
CG483_021560	COG2363	Small membrane protein
CG483_021570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG483_021575	COG2233	PERMEase
CG483_021580	COG0561	phosphatase activity
CG483_021585	COG2814	Major facilitator Superfamily
CG483_021590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG483_021595	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG483_021600	COG1131	(ABC) transporter
CG483_021605	COG2755	lipolytic protein G-D-S-L family
CG483_021610	COG0460	homoserine dehydrogenase
CG483_021615	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CG483_021630	COG0351	phosphomethylpyrimidine kinase
CG483_021640	COG1966	Carbon starvation protein
CG483_021645	COG3279	Response regulator of the LytR AlgR family
CG483_021650	COG0477	Major facilitator Superfamily
CG483_021660	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CG483_021665	COG0438	transferase activity, transferring glycosyl groups
CG483_021680	COG0840	transmembrane signaling receptor activity
CG483_021695	COG1607	acyl-coa hydrolase
CG483_021700	COG1216	Glycosyl transferase, family 2
CG483_021715	COG0463	Glycosyl transferase, family 2
CG483_021730	COG0463	Glycosyl transferase, family 2
CG483_021735	COG0488	(ABC) transporter
CG483_021740	COG1309	transcriptional regulator
CG483_021745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG483_021750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG483_021750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG483_021755	COG0628	permease
CG483_021760	COG1346	cytolysis
CG483_021770	COG3279	Response regulator of the LytR AlgR family
CG483_021780	COG2814	Major facilitator Superfamily
CG483_021785	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CG483_021790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG483_021800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG483_021805	COG3711	transcriptional antiterminator
CG483_021805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG483_021860	COG0582	viral genome integration into host DNA
CG483_021875	COG1132	(ABC) transporter
CG483_021885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG483_021895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG483_021900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CG483_021905	COG4853	Protein conserved in bacteria
CG483_021915	COG5002	protein histidine kinase activity
CG483_021920	COG0745	RESPONSE REGULATOR receiver
CG483_021945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG483_021950	COG0305	Participates in initiation and elongation during chromosome replication
CG483_021955	COG0359	binds to the 23S rRNA
CG483_021960	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CG483_021965	COG4241	membrane
CG483_021970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CG483_021975	COG0629	single-stranded DNA binding
CG483_021980	COG0360	Binds together with S18 to 16S ribosomal RNA
CG483_021985	COG0012	GTP binding
CG483_021990	COG4481	Protein conserved in bacteria
CG483_021995	COG0668	transmembrane transport
CG483_022010	COG1192	Involved in chromosome partitioning
CG483_022015	COG1475	DNA binding
CG483_022020	COG0357	Ribosomal RNA small subunit methyltransferase G
CG483_022025	COG0445	tRNA wobble uridine modification
CG483_022030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG483_022035	COG1847	R3H domain protein
CG483_022040	COG0706	membrane insertase activity
CG483_022045	COG0594	ribonuclease P activity
CG483_022095	COG1073	alpha beta
CG483_022105	COG2197	response regulator
CG483_022110	COG1476	TRANSCRIPTIONal
CG483_022285	COG2003	Belongs to the UPF0758 family
CG483_022300	COG3209	COG3209 Rhs family protein
CG483_022305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG483_022410	COG0791	NLP P60 protein
CG483_022410	COG0741	lytic transglycosylase activity
CG483_022560	COG1192	Involved in chromosome partitioning
CG483_022600	COG0457	Tetratricopeptide repeat
CG483_022610	COG4166	transmembrane transport
CG483_022645	COG4974	Belongs to the 'phage' integrase family
CG483_022725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG483_022740	COG0583	DNA-binding transcription factor activity
CG483_022760	COG1028	Short-chain dehydrogenase reductase Sdr