locus-tag	class	description
JC776_00005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JC776_00020	COG1316	TRANSCRIPTIONal
JC776_00025	COG0083	homoserine kinase activity
JC776_00035	COG0460	homoserine dehydrogenase
JC776_00045	COG0300	oxidoreductase activity
JC776_00050	COG1388	LysM domain
JC776_00050	COG0791	NLP P60 protein
JC776_00065	COG1686	Belongs to the peptidase S11 family
JC776_00090	COG0523	cobalamin synthesis protein
JC776_00100	COG0628	permease
JC776_00105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JC776_00110	COG1012	belongs to the aldehyde dehydrogenase family
JC776_00125	COG1454	alcohol dehydrogenase
JC776_00130	COG1012	belongs to the aldehyde dehydrogenase family
JC776_00135	COG1510	regulation of RNA biosynthetic process
JC776_00145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JC776_00160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JC776_00165	COG2390	Transcriptional regulator
JC776_00175	COG0083	homoserine kinase activity
JC776_00185	COG1054	Belongs to the UPF0176 family
JC776_00190	COG1914	H( )-stimulated, divalent metal cation uptake system
JC776_00200	COG4166	transmembrane transport
JC776_00205	COG0402	S-adenosylhomocysteine deaminase activity
JC776_00225	COG3384	dioxygenase
JC776_00230	COG2814	Major facilitator Superfamily
JC776_00235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC776_00265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JC776_00270	COG0129	dihydroxy-acid dehydratase activity
JC776_00280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JC776_00285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC776_00300	COG5566	PFAM Mor transcription activator
JC776_00305	COG0733	neurotransmitter:sodium symporter activity
JC776_00310	COG2244	polysaccharide biosynthetic process
JC776_00315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JC776_00320	COG2223	nitrite transmembrane transporter activity
JC776_00325	COG4166	transmembrane transport
JC776_00330	COG0488	(ABC) transporter
JC776_00335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JC776_00360	COG0109	protoheme IX farnesyltransferase activity
JC776_00370	COG2502	aspartate--ammonia ligase
JC776_00380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JC776_00385	COG1280	lysine exporter protein (LysE YggA)
JC776_00390	COG2733	membrane
JC776_00395	COG3340	Belongs to the peptidase S51 family
JC776_00400	COG0534	Mate efflux family protein
JC776_00430	COG1757	Na H antiporter
JC776_00440	COG0697	spore germination
JC776_00445	COG1802	Transcriptional regulator
JC776_00465	COG0367	asparagine synthase
JC776_00510	COG2814	Major facilitator Superfamily
JC776_00560	COG0577	efflux transmembrane transporter activity
JC776_00560	COG1136	(ABC) transporter
JC776_00565	COG4786	Flagellar basal body rod
JC776_00570	COG1419	protein localization to endoplasmic reticulum
JC776_00575	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JC776_00580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JC776_00590	COG1987	bacterial-type flagellum assembly
JC776_00595	COG1338	Plays a role in the flagellum-specific transport system
JC776_00605	COG1776	CheC inhibitor of MCP methylation
JC776_00605	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC776_00610	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC776_00620	COG0741	lytic transglycosylase activity
JC776_00625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JC776_00630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JC776_00640	COG0784	Response regulator, receiver
JC776_00640	COG0835	chemotaxis
JC776_00675	COG1157	protein secretion by the type III secretion system
JC776_00685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC776_00705	COG1815	bacterial-type flagellum-dependent cell motility
JC776_00720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JC776_00725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JC776_00730	COG1256	bacterial-type flagellum assembly
JC776_00750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JC776_00765	COG1776	CheC inhibitor of MCP methylation
JC776_00765	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC776_00770	COG2198	Histidine kinase
JC776_00770	COG0643	Histidine kinase
JC776_00775	COG2201	protein-glutamate methylesterase activity
JC776_00785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JC776_00815	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JC776_00820	COG2323	membrane
JC776_00845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JC776_00850	COG0475	glutathione-regulated potassium exporter activity
JC776_00855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JC776_00860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC776_00865	COG3162	membrane
JC776_00875	COG1278	Cold shock
JC776_00905	COG0328	RNA-DNA hybrid ribonuclease activity
JC776_00925	COG1733	regulation of RNA biosynthetic process
JC776_00930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC776_00940	COG3766	membrane
JC776_00980	COG0456	acetyltransferase
JC776_00990	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JC776_00995	COG2311	Membrane
JC776_01000	COG2233	PERMEase
JC776_01005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JC776_01010	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JC776_01015	COG1199	ATP-dependent helicase activity
JC776_01025	COG0116	Belongs to the methyltransferase superfamily
JC776_01035	COG3599	regulation of cell shape
JC776_01040	COG4474	Belongs to the UPF0398 family
JC776_01075	COG3331	DNA recombination
JC776_01080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC776_01080	COG4499	WXG100 protein secretion system (Wss), protein YukC
JC776_01090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JC776_01095	COG3935	DnaD domain protein
JC776_01115	COG1199	ATP-dependent helicase activity
JC776_01115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JC776_01120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JC776_01125	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JC776_01130	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JC776_01140	COG0617	tRNA 3'-terminal CCA addition
JC776_01145	COG0438	transferase activity, transferring glycosyl groups
JC776_01150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JC776_01155	COG1803	Methylglyoxal synthase
JC776_01160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JC776_01165	COG1694	Mazg nucleotide pyrophosphohydrolase
JC776_01170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC776_01180	COG2738	Putative neutral zinc metallopeptidase
JC776_01195	COG4347	Protein of unknown function (DUF1405)
JC776_01205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JC776_01220	COG5582	Belongs to the UPF0302 family
JC776_01225	COG0457	Tetratricopeptide repeat
JC776_01230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JC776_01235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JC776_01240	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JC776_01245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JC776_01255	COG0142	geranyltranstransferase activity
JC776_01260	COG2226	methyltransferase
JC776_01265	COG0142	geranyltranstransferase activity
JC776_01270	COG0302	gtp cyclohydrolase
JC776_01280	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JC776_01300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JC776_01305	COG1160	GTP binding
JC776_01330	COG1304	FMN binding
JC776_01340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JC776_01355	COG0492	ferredoxin-NADP+ reductase activity
JC776_01370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JC776_01385	COG1408	metallophosphoesterase
JC776_01395	COG1266	CAAX protease self-immunity
JC776_01400	COG0514	ATP-dependent DNA helicase (RecQ)
JC776_01410	COG1141	Ferredoxin
JC776_01415	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JC776_01430	COG2096	Adenosyltransferase
JC776_01435	COG5002	protein histidine kinase activity
JC776_01440	COG0745	RESPONSE REGULATOR receiver
JC776_01445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JC776_01450	COG1333	cytochrome c biogenesis protein
JC776_01460	COG1187	pseudouridine synthase activity
JC776_01465	COG0700	Nucleoside recognition
JC776_01470	COG2715	membrane protein required for spore maturation
JC776_01475	COG1686	Belongs to the peptidase S11 family
JC776_01480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JC776_01495	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JC776_01495	COG0392	lysyltransferase activity
JC776_01505	COG0813	purine-nucleoside phosphorylase activity
JC776_01510	COG5002	protein histidine kinase activity
JC776_01515	COG0582	viral genome integration into host DNA
JC776_01525	COG1801	Protein of unknown function DUF72
JC776_01530	COG3852	Histidine kinase
JC776_01540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC776_01545	COG1392	Phosphate transport regulator
JC776_01550	COG0306	phosphate transporter
JC776_01555	COG0730	response to heat
JC776_01575	COG2801	Transposase and inactivated derivatives
JC776_01585	COG1482	cell wall glycoprotein biosynthetic process
JC776_01590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC776_01590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC776_01590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC776_01595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC776_01595	COG3711	transcriptional antiterminator
JC776_01610	COG2723	6-phospho-beta-galactosidase activity
JC776_01620	COG3711	transcriptional antiterminator
JC776_01650	COG4085	toxin activity
JC776_01650	COG0737	Belongs to the 5'-nucleotidase family
JC776_01650	COG1525	nuclease
JC776_01655	COG1114	Component of the transport system for branched-chain amino acids
JC776_01660	COG2197	response regulator
JC776_01665	COG4585	Histidine kinase
JC776_01670	COG4758	membrane
JC776_01685	COG1757	Na H antiporter
JC776_01690	COG3557	Belongs to the UPF0374 family
JC776_01705	COG0733	neurotransmitter:sodium symporter activity
JC776_01710	COG1648	precorrin-2 dehydrogenase activity
JC776_01710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC776_01730	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JC776_01735	COG0529	Catalyzes the synthesis of activated sulfate
JC776_01740	COG2046	Belongs to the sulfate adenylyltransferase family
JC776_01745	COG0175	sulfate reduction
JC776_01755	COG0019	diaminopimelate decarboxylase activity
JC776_01765	COG1368	sulfuric ester hydrolase activity
JC776_01770	COG1183	phosphatidylcholine synthase activity
JC776_01785	COG0140	phosphoribosyl-ATP diphosphatase activity
JC776_01790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JC776_01795	COG0107	imidazoleglycerol-phosphate synthase activity
JC776_01800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JC776_01805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JC776_01810	COG0131	Imidazoleglycerol-phosphate dehydratase
JC776_01820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JC776_01830	COG0066	3-isopropylmalate dehydratase activity
JC776_01835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JC776_01845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JC776_01850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JC776_01855	COG0440	acetolactate synthase activity
JC776_01860	COG0028	Belongs to the TPP enzyme family
JC776_01885	COG3874	Sporulation protein YtfJ
JC776_01895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC776_01900	COG1301	dicarboxylic acid transport
JC776_01910	COG1846	Transcriptional regulator
JC776_01925	COG0534	Mate efflux family protein
JC776_01930	COG0288	reversible hydration of carbon dioxide
JC776_01935	COG3002	Belongs to the UPF0753 family
JC776_01940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JC776_01945	COG5609	conserved protein (DUF2294)
JC776_01955	COG3173	Aminoglycoside phosphotransferase
JC776_01965	COG1368	sulfuric ester hydrolase activity
JC776_01990	COG0716	FMN binding
JC776_02005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JC776_02010	COG1696	Membrane protein involved in D-alanine export
JC776_02020	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JC776_02025	COG2070	2-Nitropropane dioxygenase
JC776_02030	COG1619	proteins homologs of microcin C7 resistance protein MccF
JC776_02045	COG1522	sequence-specific DNA binding
JC776_02060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JC776_02065	COG1131	(ABC) transporter
JC776_02075	COG1131	(ABC) transporter
JC776_02080	COG1725	Transcriptional regulator
JC776_02085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JC776_02100	COG1780	Probably involved in ribonucleotide reductase function
JC776_02115	COG0456	acetyltransferase
JC776_02125	COG4873	Protein conserved in bacteria
JC776_02130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JC776_02140	COG0720	synthase
JC776_02145	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JC776_02160	COG1846	Transcriptional regulator
JC776_02165	COG3852	Histidine kinase
JC776_02175	COG2861	carbohydrate metabolic process
JC776_02185	COG0235	Class ii aldolase
JC776_02190	COG1349	DNA-binding transcription factor activity
JC776_02195	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JC776_02200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JC776_02210	COG3842	ATPase activity
JC776_02215	COG1840	ABC-type Fe3 transport system, periplasmic component
JC776_02230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC776_02235	COG3243	poly(R)-hydroxyalkanoic acid synthase
JC776_02240	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_02260	COG2030	dehydratase
JC776_02270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC776_02275	COG0861	Integral membrane protein TerC family
JC776_02280	COG2116	formate transmembrane transporter activity
JC776_02305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JC776_02310	COG2267	carboxylic ester hydrolase activity
JC776_02320	COG0584	glycerophosphoryl diester phosphodiesterase
JC776_02325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JC776_02330	COG1556	Lactate utilization protein
JC776_02335	COG1139	Iron-sulfur cluster binding protein
JC776_02340	COG0247	lactate metabolic process
JC776_02345	COG2186	Transcriptional regulator
JC776_02350	COG5002	protein histidine kinase activity
JC776_02355	COG0745	RESPONSE REGULATOR receiver
JC776_02365	COG3835	regulator
JC776_02370	COG0277	FAD linked oxidase domain protein
JC776_02375	COG0247	lactate metabolic process
JC776_02380	COG2340	Cysteine-rich secretory protein family
JC776_02390	COG0564	pseudouridine synthase activity
JC776_02400	COG2409	Drug exporters of the RND superfamily
JC776_02405	COG0671	phosphoesterase, PA-phosphatase related
JC776_02410	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JC776_02415	COG1177	transmembrane transport
JC776_02420	COG1176	ABC-type spermidine putrescine transport system, permease component I
JC776_02430	COG1012	belongs to the aldehyde dehydrogenase family
JC776_02465	COG0681	Belongs to the peptidase S26 family
JC776_02470	COG1686	Belongs to the peptidase S11 family
JC776_02495	COG0582	viral genome integration into host DNA
JC776_02545	COG0582	viral genome integration into host DNA
JC776_02550	COG0457	Tetratricopeptide repeat
JC776_02580	COG0673	inositol 2-dehydrogenase activity
JC776_02650	COG0457	Tetratricopeptide repeat
JC776_02665	COG0179	Fumarylacetoacetate (FAA) hydrolase
JC776_02670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC776_02675	COG3162	membrane
JC776_02680	COG0196	riboflavin kinase activity
JC776_02695	COG1012	belongs to the aldehyde dehydrogenase family
JC776_02700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JC776_02705	COG0583	DNA-binding transcription factor activity
JC776_02715	COG0567	Dehydrogenase, E1 component
JC776_02720	COG0508	dehydrogenase complex catalyzes the overall conversion of
JC776_02760	COG5634	Uncharacterized conserved protein (DUF2278)
JC776_02765	COG1620	l-lactate permease
JC776_02775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC776_02780	COG5492	domain, Protein
JC776_02795	COG2382	esterase
JC776_02800	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JC776_02825	COG1091	dTDP-4-dehydrorhamnose reductase activity
JC776_02840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JC776_02860	COG0463	Glycosyl transferase, family 2
JC776_02860	COG0457	Tetratricopeptide repeat
JC776_02880	COG1216	Glycosyl transferase, family 2
JC776_02925	COG0772	Belongs to the SEDS family
JC776_02930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JC776_02940	COG0564	pseudouridine synthase activity
JC776_02950	COG2357	RelA SpoT domain protein
JC776_02960	COG4116	CYTH
JC776_02965	COG2346	COG2346, Truncated hemoglobins
JC776_02975	COG1164	Oligoendopeptidase f
JC776_02995	COG0861	Integral membrane protein TerC family
JC776_03010	COG4166	transmembrane transport
JC776_03015	COG0534	Mate efflux family protein
JC776_03020	COG4608	Belongs to the ABC transporter superfamily
JC776_03025	COG0444	Belongs to the ABC transporter superfamily
JC776_03030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC776_03035	COG0601	transmembrane transport
JC776_03040	COG4166	transmembrane transport
JC776_03050	COG0180	Tryptophanyl-tRNA synthetase
JC776_03060	COG5504	Zn-dependent protease
JC776_03065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JC776_03070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JC776_03085	COG2267	carboxylic ester hydrolase activity
JC776_03105	COG0561	phosphatase activity
JC776_03120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC776_03135	COG2996	Protein conserved in bacteria
JC776_03140	COG1666	GTP binding
JC776_03145	COG0366	Alpha amylase catalytic
JC776_03145	COG1874	Beta-galactosidase
JC776_03150	COG0753	catalase activity
JC776_03160	COG0367	asparagine synthase
JC776_03180	COG0179	Fumarylacetoacetate (FAA) hydrolase
JC776_03220	COG1074	ATP-dependent DNA helicase activity
JC776_03225	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JC776_03235	COG0398	Pfam SNARE associated Golgi protein
JC776_03240	COG4903	ComK protein
JC776_03245	COG1278	Cold shock
JC776_03250	COG2224	Isocitrate lyase
JC776_03255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JC776_03270	COG0697	spore germination
JC776_03275	COG0840	transmembrane signaling receptor activity
JC776_03280	COG0501	Belongs to the peptidase M48B family
JC776_03300	COG0745	RESPONSE REGULATOR receiver
JC776_03305	COG2205	protein histidine kinase activity
JC776_03320	COG0318	PFAM AMP-dependent synthetase and ligase
JC776_03325	COG0095	Lipoate-protein ligase
JC776_03330	COG1234	tRNA 3'-trailer cleavage
JC776_03340	COG1609	Transcriptional regulator
JC776_03350	COG0438	transferase activity, transferring glycosyl groups
JC776_03350	COG1216	Glycosyl transferase, family 2
JC776_03360	COG1309	transcriptional regulator
JC776_03390	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JC776_03395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JC776_03400	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JC776_03405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC776_03410	COG2329	Antibiotic biosynthesis monooxygenase
JC776_03420	COG3402	PFAM membrane-flanked domain
JC776_03440	COG4473	ABC transporter
JC776_03445	COG1131	(ABC) transporter
JC776_03450	COG0537	adenosine 5'-monophosphoramidase activity
JC776_03455	COG4980	gas vesicle protein
JC776_03460	COG1846	Transcriptional regulator
JC776_03480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JC776_03485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JC776_03490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JC776_03495	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JC776_03505	COG1316	TRANSCRIPTIONal
JC776_03515	COG0745	RESPONSE REGULATOR receiver
JC776_03520	COG5002	protein histidine kinase activity
JC776_03525	COG1136	(ABC) transporter
JC776_03530	COG0577	efflux transmembrane transporter activity
JC776_03535	COG3481	metal-dependent phosphohydrolase, HD sub domain
JC776_03540	COG4717	serine-type aminopeptidase activity
JC776_03545	COG0420	3'-5' exonuclease activity
JC776_03580	COG2376	Dihydroxyacetone kinase
JC776_03590	COG2723	6-phospho-beta-galactosidase activity
JC776_03595	COG1263	PTS System
JC776_03595	COG2190	(PTS) system
JC776_03595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC776_03600	COG3711	transcriptional antiterminator
JC776_03615	COG4641	Protein conserved in bacteria
JC776_03660	COG3246	L-lysine catabolic process to acetate
JC776_03675	COG1064	alcohol dehydrogenase
JC776_03685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC776_03695	COG0473	3-isopropylmalate dehydrogenase activity
JC776_03700	COG1012	belongs to the aldehyde dehydrogenase family
JC776_03705	COG4638	Rieske (2fe-2S)
JC776_03710	COG3829	transcription factor binding
JC776_03720	COG1061	Type III restriction enzyme res subunit
JC776_03735	COG0494	nUDIX hydrolase
JC776_03780	COG1131	(ABC) transporter
JC776_03820	COG1476	TRANSCRIPTIONal
JC776_03925	COG1115	amino acid carrier protein
JC776_03930	COG0772	Belongs to the SEDS family
JC776_03935	COG2239	Acts as a magnesium transporter
JC776_03950	COG1363	Peptidase, m42
JC776_03960	COG1024	Enoyl-CoA hydratase
JC776_03975	COG1696	Membrane protein involved in D-alanine export
JC776_03995	COG0860	N-Acetylmuramoyl-L-alanine amidase
JC776_04005	COG2244	polysaccharide biosynthetic process
JC776_04030	COG0318	PFAM AMP-dependent synthetase and ligase
JC776_04035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JC776_04045	COG0561	phosphatase activity
JC776_04050	COG2094	Belongs to the DNA glycosylase MPG family
JC776_04110	COG2197	response regulator
JC776_04115	COG4585	Histidine kinase
JC776_04120	COG3679	Belongs to the UPF0342 family
JC776_04125	COG4399	Belongs to the UPF0754 family
JC776_04130	COG0189	ligase activity
JC776_04145	COG1126	abc transporter atp-binding protein
JC776_04150	COG0765	amino acid transport
JC776_04155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC776_04160	COG1132	(ABC) transporter
JC776_04165	COG1132	(ABC) transporter
JC776_04170	COG1012	belongs to the aldehyde dehydrogenase family
JC776_04180	COG0531	amino acid
JC776_04190	COG1522	sequence-specific DNA binding
JC776_04225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC776_04225	COG1263	PTS System
JC776_04230	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JC776_04240	COG1737	Transcriptional regulator
JC776_04245	COG0475	glutathione-regulated potassium exporter activity
JC776_04300	COG3546	catalase activity
JC776_04305	COG1114	Component of the transport system for branched-chain amino acids
JC776_04315	COG1136	(ABC) transporter
JC776_04320	COG0577	efflux transmembrane transporter activity
JC776_04335	COG1283	sodium-dependent phosphate transmembrane transporter activity
JC776_04340	COG1316	TRANSCRIPTIONal
JC776_04350	COG2719	SpoVR family
JC776_04360	COG0778	Nitroreductase
JC776_04415	COG1376	ErfK ybiS ycfS ynhG family protein
JC776_04420	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_04425	COG2252	PERMEase
JC776_04435	COG1846	Transcriptional regulator
JC776_04460	COG0735	belongs to the Fur family
JC776_04470	COG2816	NAD+ diphosphatase activity
JC776_04480	COG4974	Belongs to the 'phage' integrase family
JC776_04490	COG2205	protein histidine kinase activity
JC776_04495	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JC776_04500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JC776_04530	COG0351	phosphomethylpyrimidine kinase
JC776_04535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC776_04540	COG2022	thiamine diphosphate biosynthetic process
JC776_04545	COG2104	thiamine diphosphate biosynthetic process
JC776_04550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC776_04555	COG0352	thiamine-phosphate diphosphorylase activity
JC776_04560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JC776_04565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC776_04570	COG1116	anion transmembrane transporter activity
JC776_04575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JC776_04605	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JC776_04690	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC776_04730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC776_04735	COG0581	inorganic phosphate transmembrane transporter activity
JC776_04740	COG0573	inorganic phosphate transmembrane transporter activity
JC776_04745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JC776_04750	COG1918	ferrous iron import across plasma membrane
JC776_04750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JC776_04755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JC776_04760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JC776_04775	COG0531	amino acid
JC776_04780	COG0697	spore germination
JC776_04785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC776_04800	COG4990	cell redox homeostasis
JC776_04805	COG0833	amino acid
JC776_04810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JC776_04815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JC776_04830	COG0475	glutathione-regulated potassium exporter activity
JC776_04830	COG0569	domain protein
JC776_04840	COG2153	protein acetylation
JC776_04845	COG1113	amino acid transport
JC776_04855	COG1114	Component of the transport system for branched-chain amino acids
JC776_04890	COG1476	TRANSCRIPTIONal
JC776_04895	COG3584	3D domain protein
JC776_04895	COG1388	LysM domain
JC776_04900	COG0840	transmembrane signaling receptor activity
JC776_04925	COG3568	Endonuclease Exonuclease Phosphatase
JC776_04965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JC776_04970	COG1879	ABC-type sugar transport system periplasmic component
JC776_04975	COG1172	Belongs to the binding-protein-dependent transport system permease family
JC776_04985	COG1869	D-ribose catabolic process
JC776_04990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JC776_04995	COG1609	Transcriptional regulator
JC776_05000	COG0477	Major facilitator Superfamily
JC776_05005	COG1846	Transcriptional regulator
JC776_05010	COG2271	Major facilitator Superfamily
JC776_05020	COG4608	Belongs to the ABC transporter superfamily
JC776_05025	COG0601	transmembrane transport
JC776_05035	COG0747	negative chemotaxis
JC776_05045	COG0589	response to stress
JC776_05050	COG0659	secondary active sulfate transmembrane transporter activity
JC776_05060	COG0745	RESPONSE REGULATOR receiver
JC776_05065	COG5002	protein histidine kinase activity
JC776_05075	COG0833	amino acid
JC776_05080	COG0765	amino acid transport
JC776_05085	COG0765	amino acid transport
JC776_05090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC776_05095	COG1126	abc transporter atp-binding protein
JC776_05100	COG1115	amino acid carrier protein
JC776_05105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC776_05110	COG0531	amino acid
JC776_05115	COG0714	Associated with various cellular activities
JC776_05120	COG4548	von Willebrand factor, type A
JC776_05130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JC776_05135	COG0156	8-amino-7-oxononanoate synthase activity
JC776_05140	COG3104	oligopeptide transport
JC776_05155	COG1620	l-lactate permease
JC776_05160	COG1027	Aspartate ammonia-lyase
JC776_05165	COG1253	flavin adenine dinucleotide binding
JC776_05175	COG1316	TRANSCRIPTIONal
JC776_05180	COG2720	vancomycin resistance protein
JC776_05200	COG2217	Heavy metal translocating P-type atpase
JC776_05215	COG3227	Zinc metalloprotease (Elastase)
JC776_05230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JC776_05235	COG2217	Heavy metal translocating P-type atpase
JC776_05240	COG0640	Transcriptional regulator
JC776_05250	COG0531	amino acid
JC776_05260	COG0840	transmembrane signaling receptor activity
JC776_05270	COG2427	Protein of unknown function (DUF1641)
JC776_05275	COG3383	formate dehydrogenase (NAD+) activity
JC776_05280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JC776_05285	COG0745	RESPONSE REGULATOR receiver
JC776_05290	COG5002	protein histidine kinase activity
JC776_05305	COG0281	malic enzyme
JC776_05310	COG3493	citrate carrier protein
JC776_05315	COG4565	transcriptional regulatory protein
JC776_05320	COG3290	protein histidine kinase activity
JC776_05330	COG4990	cell redox homeostasis
JC776_05365	COG2268	Band 7 protein
JC776_05370	COG1585	Membrane protein implicated in regulation of membrane protease activity
JC776_05380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JC776_05425	COG1280	lysine exporter protein (LysE YggA)
JC776_05440	COG2718	Belongs to the UPF0229 family
JC776_05445	COG2766	serine protein kinase
JC776_05450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JC776_05470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JC776_05475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JC776_05480	COG0217	transcriptional regulatory protein
JC776_05485	COG0457	Tetratricopeptide repeat
JC776_05505	COG3157	Type VI secretion system effector, Hcp
JC776_05605	COG0735	belongs to the Fur family
JC776_05610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JC776_05630	COG4555	ABC transporter
JC776_05635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JC776_05640	COG0070	glutamate synthase
JC776_05640	COG0067	glutamate synthase
JC776_05640	COG0069	glutamate synthase activity
JC776_05645	COG4129	membrane
JC776_05650	COG1132	(ABC) transporter
JC776_05655	COG3557	Belongs to the UPF0374 family
JC776_05675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JC776_05680	COG1194	a g-specific adenine glycosylase
JC776_05685	COG1988	membrane-bound metal-dependent
JC776_05710	COG2137	regulation of response to DNA damage stimulus
JC776_05715	COG0402	S-adenosylhomocysteine deaminase activity
JC776_05730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JC776_05735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JC776_05745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JC776_05745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JC776_05755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JC776_05760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC776_05760	COG1263	PTS System
JC776_05765	COG2066	Belongs to the glutaminase family
JC776_05795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JC776_05820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JC776_05845	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JC776_05865	COG0535	radical SAM domain protein
JC776_05875	COG0387	Pfam Sodium calcium exchanger
JC776_05890	COG0586	Pfam SNARE associated Golgi protein
JC776_05900	COG0681	Belongs to the peptidase S26 family
JC776_05910	COG0697	spore germination
JC776_05915	COG2217	Heavy metal translocating P-type atpase
JC776_05920	COG1295	ribonuclease BN
JC776_05930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JC776_05935	COG4840	Belongs to the UPF0435 family
JC776_05945	COG3853	Toxic anion resistance protein (TelA)
JC776_05955	COG0861	Integral membrane protein TerC family
JC776_05960	COG2310	stress, protein
JC776_05965	COG2310	stress, protein
JC776_05970	COG2310	stress, protein
JC776_05995	COG2270	Major facilitator Superfamily
JC776_06000	COG2801	Transposase and inactivated derivatives
JC776_06005	COG2963	transposase activity
JC776_06085	COG1116	anion transmembrane transporter activity
JC776_06095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC776_06115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JC776_06125	COG0352	thiamine-phosphate diphosphorylase activity
JC776_06130	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JC776_06135	COG4607	ABC-type enterochelin transport system periplasmic component
JC776_06140	COG4604	ABC transporter, ATP-binding protein
JC776_06145	COG4605	iron ion homeostasis
JC776_06150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC776_06170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC776_06170	COG1263	PTS System
JC776_06170	COG2190	(PTS) system
JC776_06175	COG0366	Alpha amylase catalytic
JC776_06185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JC776_06190	COG0549	Belongs to the carbamate kinase family
JC776_06205	COG2235	arginine
JC776_06220	COG0840	transmembrane signaling receptor activity
JC776_06230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC776_06235	COG0765	amino acid transport
JC776_06245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC776_06245	COG0723	plastoquinol--plastocyanin reductase activity
JC776_06250	COG2814	Major facilitator Superfamily
JC776_06255	COG3541	Predicted nucleotidyltransferase
JC776_06285	COG5002	protein histidine kinase activity
JC776_06290	COG0166	Belongs to the GPI family
JC776_06300	COG0492	ferredoxin-NADP+ reductase activity
JC776_06305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JC776_06310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC776_06315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC776_06355	COG0714	Associated with various cellular activities
JC776_06380	COG0450	alkyl hydroperoxide reductase
JC776_06395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JC776_06400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JC776_06405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC776_06415	COG2309	aminopeptidase activity
JC776_06420	COG2076	Multidrug Resistance protein
JC776_06425	COG1012	belongs to the aldehyde dehydrogenase family
JC776_06430	COG0531	amino acid
JC776_06440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JC776_06445	COG0546	phosphoglycolate phosphatase activity
JC776_06450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JC776_06455	COG1597	lipid kinase activity
JC776_06460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JC776_06465	COG0154	amidase activity
JC776_06470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JC776_06475	COG4682	membrane
JC776_06490	COG1464	Belongs to the NlpA lipoprotein family
JC776_06495	COG2011	ABC-type metal ion transport system permease component
JC776_06505	COG1335	isochorismatase
JC776_06510	COG1012	belongs to the aldehyde dehydrogenase family
JC776_06520	COG4851	CamS sex pheromone cAM373 precursor
JC776_06525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JC776_06530	COG0210	DNA helicase
JC776_06535	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JC776_06555	COG0583	DNA-binding transcription factor activity
JC776_06565	COG0151	Belongs to the GarS family
JC776_06570	COG0138	bifunctional purine biosynthesis protein purh
JC776_06575	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JC776_06580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JC776_06585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JC776_06590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JC776_06595	COG0047	phosphoribosylformylglycinamidine synthase activity
JC776_06600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JC776_06605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JC776_06610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JC776_06615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JC776_06620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JC776_06640	COG0697	spore germination
JC776_06660	COG0745	RESPONSE REGULATOR receiver
JC776_06665	COG2205	protein histidine kinase activity
JC776_06730	COG5002	protein histidine kinase activity
JC776_06740	COG2252	PERMEase
JC776_06745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JC776_06745	COG0519	Catalyzes the synthesis of GMP from XMP
JC776_06750	COG0459	protein refolding
JC776_06755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JC776_06760	COG1266	CAAX protease self-immunity
JC776_06770	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JC776_06775	COG0488	(ABC) transporter
JC776_06785	COG0456	acetyltransferase
JC776_06790	COG1214	PFAM Peptidase M22, glycoprotease
JC776_06795	COG0802	atpase or kinase
JC776_06845	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC776_06885	COG3091	SprT-like family
JC776_06895	COG2183	response to ionizing radiation
JC776_06900	COG2337	Toxic component of a toxin-antitoxin (TA) module
JC776_06905	COG0864	Transcriptional regulator
JC776_06915	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JC776_06920	COG0736	holo-[acyl-carrier-protein] synthase activity
JC776_06925	COG0457	Tetratricopeptide repeat
JC776_06925	COG0705	Rhomboid family
JC776_06935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JC776_06940	COG1181	Belongs to the D-alanine--D-alanine ligase family
JC776_06945	COG2814	Major facilitator Superfamily
JC776_06955	COG0179	Fumarylacetoacetate (FAA) hydrolase
JC776_06960	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JC776_06980	COG0561	phosphatase activity
JC776_06985	COG4608	Belongs to the ABC transporter superfamily
JC776_06990	COG0444	Belongs to the ABC transporter superfamily
JC776_06995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC776_07000	COG0601	transmembrane transport
JC776_07005	COG0747	negative chemotaxis
JC776_07015	COG0842	Transport permease protein
JC776_07020	COG0842	Transport permease protein
JC776_07020	COG1511	domain protein
JC776_07025	COG1131	(ABC) transporter
JC776_07030	COG2197	response regulator
JC776_07035	COG4585	Histidine kinase
JC776_07060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JC776_07065	COG2146	nitrite reductase [NAD(P)H] activity
JC776_07070	COG1587	Uroporphyrinogen-III synthase
JC776_07070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC776_07080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC776_07080	COG1648	precorrin-2 dehydrogenase activity
JC776_07085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC776_07090	COG0204	Acyl-transferase
JC776_07095	COG1910	domain protein
JC776_07100	COG0725	ABC transporter, periplasmic molybdate-binding protein
JC776_07105	COG4149	molybdate abc transporter
JC776_07115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JC776_07120	COG0656	L-ascorbic acid biosynthetic process
JC776_07130	COG1309	transcriptional regulator
JC776_07140	COG2207	Transcriptional regulator
JC776_07150	COG4166	transmembrane transport
JC776_07155	COG4608	Belongs to the ABC transporter superfamily
JC776_07160	COG0444	Belongs to the ABC transporter superfamily
JC776_07165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC776_07170	COG0601	transmembrane transport
JC776_07180	COG2814	Major facilitator Superfamily
JC776_07210	COG3681	Belongs to the UPF0597 family
JC776_07215	COG3681	Belongs to the UPF0597 family
JC776_07315	COG0602	queuosine metabolic process
JC776_07320	COG1396	sequence-specific DNA binding
JC776_07350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JC776_07360	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JC776_07440	COG0726	polysaccharide deacetylase
JC776_07445	COG2194	sulfuric ester hydrolase activity
JC776_07455	COG0489	protein tyrosine kinase activity
JC776_07460	COG0860	N-Acetylmuramoyl-L-alanine amidase
JC776_07470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JC776_07475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JC776_07485	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JC776_07505	COG0202	RNA polymerase activity
JC776_07510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JC776_07515	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JC776_07520	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JC776_07530	COG0024	Methionine aminopeptidase
JC776_07535	COG0563	adenylate kinase activity
JC776_07540	COG0201	protein transport
JC776_07545	COG0200	Binds to the 23S rRNA
JC776_07550	COG1841	ribosomal large subunit assembly
JC776_07555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JC776_07560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JC776_07570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JC776_07580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JC776_07585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JC776_07590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JC776_07595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JC776_07600	COG0255	Belongs to the universal ribosomal protein uL29 family
JC776_07605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JC776_07610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JC776_07615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JC776_07620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JC776_07625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JC776_07630	COG0089	rRNA binding
JC776_07635	COG0088	Forms part of the polypeptide exit tunnel
JC776_07640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JC776_07650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JC776_07655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JC776_07660	COG0049	tRNA binding
JC776_07665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JC776_07670	COG1358	cellular component organization or biogenesis
JC776_07675	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JC776_07685	COG2813	Specifically methylates the guanine in position
JC776_07690	COG0222	ribosome binding
JC776_07695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JC776_07700	COG0081	regulation of translation
JC776_07705	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JC776_07710	COG0250	Participates in transcription elongation, termination and antitermination
JC776_07720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JC776_07730	COG3688	RNA-binding protein containing a PIN domain
JC776_07735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JC776_07745	COG0215	cysteine-tRNA ligase activity
JC776_07750	COG1045	serine acetyltransferase
JC776_07755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JC776_07760	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JC776_07765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JC776_07770	COG4956	integral membrane protein (PIN domain superfamily)
JC776_07780	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JC776_07785	COG0542	response to heat
JC776_07790	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JC776_07795	COG3880	PFAM UvrB UvrC protein
JC776_07845	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC776_07880	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JC776_07885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JC776_07890	COG1396	sequence-specific DNA binding
JC776_07895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JC776_07900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JC776_07905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JC776_07910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JC776_07915	COG0512	Glutamine amidotransferase of anthranilate synthase
JC776_07920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JC776_07925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JC776_07930	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JC776_07935	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JC776_07940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JC776_07945	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JC776_07955	COG2208	phosphoserine phosphatase activity
JC776_07970	COG1098	S1 RNA binding domain
JC776_07990	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JC776_07995	COG3956	TIGRFAM MazG family protein
JC776_08000	COG2244	polysaccharide biosynthetic process
JC776_08005	COG2002	toxin-antitoxin pair type II binding
JC776_08010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JC776_08020	COG0193	aminoacyl-tRNA hydrolase activity
JC776_08030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JC776_08035	COG2088	sporulation resulting in formation of a cellular spore
JC776_08040	COG0251	oxidation-reduction process
JC776_08045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JC776_08050	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JC776_08060	COG4466	Protein conserved in bacteria
JC776_08070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JC776_08080	COG0084	hydrolase, TatD family'
JC776_08090	COG2002	toxin-antitoxin pair type II binding
JC776_08095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JC776_08105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JC776_08110	COG4467	Involved in initiation control of chromosome replication
JC776_08115	COG1774	PSP1 C-terminal conserved region
JC776_08120	COG0470	DNA polymerase III
JC776_08125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JC776_08130	COG1982	Orn Lys Arg decarboxylase major
JC776_08170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JC776_08175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JC776_08180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JC776_08190	COG0590	tRNA wobble adenosine to inosine editing
JC776_08195	COG1335	isochorismatase
JC776_08200	COG1428	Deoxynucleoside kinase
JC776_08205	COG1428	Deoxynucleoside kinase
JC776_08220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JC776_08225	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JC776_08230	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JC776_08235	COG1686	Belongs to the peptidase S11 family
JC776_08240	COG0516	GMP reductase activity
JC776_08240	COG0517	IMP dehydrogenase activity
JC776_08275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JC776_08280	COG0187	DNA topoisomerase II activity
JC776_08285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JC776_08290	COG2501	S4 domain
JC776_08295	COG0592	DNA-directed DNA polymerase activity
JC776_08300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JC776_08305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JC776_08310	COG0594	ribonuclease P activity
JC776_08315	COG0706	membrane insertase activity
JC776_08320	COG1847	R3H domain protein
JC776_08325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JC776_08330	COG0445	tRNA wobble uridine modification
JC776_08335	COG0357	Ribosomal RNA small subunit methyltransferase G
JC776_08340	COG1475	DNA binding
JC776_08345	COG1192	Involved in chromosome partitioning
JC776_08350	COG1475	DNA binding
JC776_08360	COG0668	transmembrane transport
JC776_08365	COG4481	Protein conserved in bacteria
JC776_08370	COG0012	GTP binding
JC776_08375	COG0360	Binds together with S18 to 16S ribosomal RNA
JC776_08385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JC776_08390	COG4241	membrane
JC776_08395	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JC776_08400	COG0359	binds to the 23S rRNA
JC776_08405	COG0305	Participates in initiation and elongation during chromosome replication
JC776_08410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JC776_08435	COG0745	RESPONSE REGULATOR receiver
JC776_08440	COG5002	protein histidine kinase activity
JC776_08450	COG4853	Protein conserved in bacteria
JC776_08455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JC776_08460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JC776_08470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JC776_08480	COG1132	(ABC) transporter
JC776_08495	COG0582	viral genome integration into host DNA
JC776_08550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC776_08550	COG3711	transcriptional antiterminator
JC776_08555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JC776_08565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JC776_08570	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JC776_08575	COG2814	Major facilitator Superfamily
JC776_08580	COG3275	phosphorelay sensor kinase activity
JC776_08585	COG3279	Response regulator of the LytR AlgR family
JC776_08595	COG1346	cytolysis
JC776_08600	COG0628	permease
JC776_08605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC776_08605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC776_08610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC776_08615	COG1309	transcriptional regulator
JC776_08620	COG0488	(ABC) transporter
JC776_08625	COG0463	Glycosyl transferase, family 2
JC776_08640	COG0463	Glycosyl transferase, family 2
JC776_08655	COG1216	Glycosyl transferase, family 2
JC776_08660	COG1607	acyl-coa hydrolase
JC776_08675	COG0840	transmembrane signaling receptor activity
JC776_08690	COG0438	transferase activity, transferring glycosyl groups
JC776_08695	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JC776_08700	COG0477	Major facilitator Superfamily
JC776_08705	COG3279	Response regulator of the LytR AlgR family
JC776_08710	COG1966	Carbon starvation protein
JC776_08720	COG0351	phosphomethylpyrimidine kinase
JC776_08730	COG2873	o-acetylhomoserine
JC776_08735	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JC776_08740	COG0460	homoserine dehydrogenase
JC776_08745	COG2755	lipolytic protein G-D-S-L family
JC776_08750	COG1131	(ABC) transporter
JC776_08755	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JC776_08760	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JC776_08765	COG2814	Major facilitator Superfamily
JC776_08770	COG0561	phosphatase activity
JC776_08775	COG2233	PERMEase
JC776_08780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JC776_08790	COG2363	Small membrane protein
JC776_08800	COG3773	Cell wall hydrolase
JC776_08810	COG3253	May function as heme-dependent peroxidase
JC776_08815	COG0280	phosphate acetyltransferase
JC776_08830	COG4844	belongs to the
JC776_08835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC776_08840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC776_08845	COG1120	ATPase activity
JC776_08850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JC776_08855	COG1078	dGTPase activity
JC776_08865	COG1994	Peptidase M50
JC776_08875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC776_08880	COG0584	glycerophosphoryl diester phosphodiesterase
JC776_08885	COG0789	Transcriptional regulator
JC776_08890	COG2814	Major facilitator Superfamily
JC776_08895	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JC776_08900	COG0010	Belongs to the arginase family
JC776_08915	COG1619	proteins homologs of microcin C7 resistance protein MccF
JC776_08920	COG4506	Protein conserved in bacteria
JC776_08935	COG2234	aminopeptidase activity
JC776_08940	COG0024	Methionine aminopeptidase
JC776_08945	COG1131	(ABC) transporter
JC776_08950	COG0842	Transport permease protein
JC776_08955	COG4585	Histidine kinase
JC776_08960	COG2197	response regulator
JC776_08975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JC776_08980	COG0247	lactate metabolic process
JC776_08980	COG2181	nitrate reductase activity
JC776_08985	COG0183	Belongs to the thiolase family
JC776_08990	COG1250	3-hydroxyacyl-CoA dehydrogenase
JC776_08995	COG1960	acyl-CoA dehydrogenase activity
JC776_09000	COG1960	acyl-CoA dehydrogenase activity
JC776_09015	COG0504	CTP synthase activity
JC776_09020	COG4821	SIS domain
JC776_09040	COG1494	fructose-1,6-bisphosphatase
JC776_09045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JC776_09055	COG1435	thymidine kinase activity
JC776_09060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JC776_09065	COG2890	protein-(glutamine-N5) methyltransferase activity
JC776_09080	COG0009	L-threonylcarbamoyladenylate synthase
JC776_09095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JC776_09100	COG2259	Doxx family
JC776_09120	COG0698	ribose 5-phosphate isomerase
JC776_09130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JC776_09135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JC776_09160	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JC776_09165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JC776_09170	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JC776_09175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JC776_09180	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JC776_09185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JC776_09190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JC776_09205	COG3300	MHYT domain
JC776_09205	COG5001	Diguanylate cyclase
JC776_09210	COG3300	MHYT domain
JC776_09210	COG5001	Diguanylate cyclase
JC776_09215	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC776_09220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC776_09225	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC776_09230	COG0649	NAD binding
JC776_09235	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JC776_09245	COG0839	Belongs to the complex I subunit 6 family
JC776_09250	COG0713	ATP synthesis coupled electron transport
JC776_09255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JC776_09260	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC776_09265	COG1007	ATP synthesis coupled electron transport
JC776_09270	COG4836	Membrane
JC776_09285	COG2385	sporulation resulting in formation of a cellular spore
JC776_09290	COG3279	Response regulator of the LytR AlgR family
JC776_09305	COG0739	heme binding
JC776_09315	COG1609	Transcriptional regulator
JC776_09330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JC776_09335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JC776_09340	COG0463	Glycosyl transferase, family 2
JC776_09340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JC776_09345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JC776_09350	COG1682	transport, permease protein
JC776_09355	COG1134	teichoic acid transport
JC776_09360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JC776_09360	COG1215	transferase activity, transferring glycosyl groups
JC776_09370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JC776_09380	COG0745	RESPONSE REGULATOR receiver
JC776_09385	COG3850	Histidine kinase
JC776_09385	COG5002	protein histidine kinase activity
JC776_09420	COG1136	(ABC) transporter
JC776_09425	COG0577	efflux transmembrane transporter activity
JC776_09465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JC776_09470	COG4715	Zinc finger, swim domain protein
JC776_09485	COG3584	3D domain protein
JC776_09485	COG1388	LysM domain
JC776_09490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JC776_09495	COG1215	transferase activity, transferring glycosyl groups
JC776_09505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC776_09510	COG0791	NLP P60 protein
JC776_09510	COG1388	LysM domain
JC776_09520	COG1368	sulfuric ester hydrolase activity
JC776_09530	COG2389	metal-binding protein
JC776_09535	COG1620	l-lactate permease
JC776_09540	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JC776_09545	COG1294	oxidase, subunit
JC776_09550	COG1271	oxidase subunit
JC776_09560	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JC776_09565	COG1301	dicarboxylic acid transport
JC776_09570	COG1447	Phosphotransferase system cellobiose-specific component IIA
JC776_09585	COG1447	Phosphotransferase system cellobiose-specific component IIA
JC776_09590	COG1486	melibiose metabolic process
JC776_09605	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JC776_09605	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JC776_09615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JC776_09620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JC776_09630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JC776_09640	COG1316	TRANSCRIPTIONal
JC776_09645	COG1739	Uncharacterized protein family UPF0029
JC776_09650	COG1307	EDD domain protein, DegV family
JC776_09655	COG1733	regulation of RNA biosynthetic process
JC776_09660	COG1388	LysM domain
JC776_09660	COG0791	NLP P60 protein
JC776_09665	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JC776_09670	COG1040	competence protein
JC776_09675	COG1278	Cold shock
JC776_09700	COG2884	Cell division ATP-binding protein ftsE
JC776_09705	COG2177	Part of the ABC transporter FtsEX involved in
JC776_09710	COG3409	Peptidoglycan-binding domain 1 protein
JC776_09710	COG0793	Belongs to the peptidase S41A family
JC776_09715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JC776_09730	COG0583	DNA-binding transcription factor activity
JC776_09755	COG0789	Transcriptional regulator
JC776_09770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JC776_09780	COG1950	PFAM Membrane protein of
JC776_09785	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JC776_09790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JC776_09800	COG0110	maltose O-acetyltransferase activity
JC776_09805	COG0457	Tetratricopeptide repeat
JC776_09810	COG0492	ferredoxin-NADP+ reductase activity
JC776_09820	COG1051	belongs to the nudix hydrolase family
JC776_09825	COG1660	Displays ATPase and GTPase activities
JC776_09830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JC776_09835	COG1481	regulation of sporulation
JC776_09840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC776_09850	COG2323	membrane
JC776_09865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JC776_09910	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JC776_09925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JC776_09930	COG0126	phosphoglycerate kinase activity
JC776_09935	COG0149	triose-phosphate isomerase activity
JC776_09940	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JC776_09945	COG0148	phosphopyruvate hydratase activity
JC776_09955	COG1346	cytolysis
JC776_09960	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JC776_09965	COG1647	Serine aminopeptidase, S33
JC776_09970	COG0557	exoribonuclease II activity
JC776_09975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JC776_09990	COG0697	spore germination
JC776_10010	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JC776_10020	COG4977	sequence-specific DNA binding
JC776_10020	COG1917	Cupin 2, conserved barrel domain protein
JC776_10025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC776_10040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JC776_10055	COG1252	NADH dehydrogenase
JC776_10070	COG2910	NAD(P)H-binding
JC776_10075	COG1115	amino acid carrier protein
JC776_10080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC776_10085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC776_10105	COG1121	(ABC) transporter
JC776_10110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JC776_10115	COG0803	Belongs to the bacterial solute-binding protein 9 family
JC776_10135	COG1611	Belongs to the LOG family
JC776_10140	COG0783	Belongs to the Dps family
JC776_10155	COG1741	Belongs to the pirin family
JC776_10160	COG3227	Zinc metalloprotease (Elastase)
JC776_10165	COG2151	metal-sulfur cluster biosynthetic enzyme
JC776_10170	COG0840	transmembrane signaling receptor activity
JC776_10175	COG0840	transmembrane signaling receptor activity
JC776_10180	COG5002	protein histidine kinase activity
JC776_10185	COG0745	RESPONSE REGULATOR receiver
JC776_10190	COG1376	ErfK ybiS ycfS ynhG family protein
JC776_10200	COG0586	Pfam SNARE associated Golgi protein
JC776_10210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC776_10220	COG0706	membrane insertase activity
JC776_10225	COG0531	amino acid
JC776_10245	COG0840	transmembrane signaling receptor activity
JC776_10250	COG0011	TIGRFAM Protein of
JC776_10270	COG1686	Belongs to the peptidase S11 family
JC776_10280	COG1250	3-hydroxyacyl-CoA dehydrogenase
JC776_10280	COG1024	Enoyl-CoA hydratase
JC776_10285	COG0183	Belongs to the thiolase family
JC776_10290	COG1960	acyl-CoA dehydrogenase activity
JC776_10335	COG1393	Belongs to the ArsC family
JC776_10340	COG0509	glycine decarboxylation via glycine cleavage system
JC776_10345	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JC776_10350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC776_10365	COG2011	ABC-type metal ion transport system permease component
JC776_10370	COG1464	Belongs to the NlpA lipoprotein family
JC776_10375	COG0396	ATPase activity
JC776_10380	COG0719	Fe-S assembly protein
JC776_10385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JC776_10390	COG0822	iron-sulfur transferase activity
JC776_10395	COG0719	Fe-S assembly protein
JC776_10410	COG0737	Belongs to the 5'-nucleotidase family
JC776_10415	COG3377	Domain of unknown function (DUF1805)
JC776_10425	COG0739	heme binding
JC776_10430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JC776_10445	COG4377	Putative membrane peptidase family (DUF2324)
JC776_10450	COG0789	Transcriptional regulator
JC776_10460	COG4470	Protein conserved in bacteria
JC776_10470	COG1494	fructose-1,6-bisphosphatase
JC776_10475	COG2445	Protein of unknown function DUF86
JC776_10485	COG0647	UMP catabolic process
JC776_10495	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JC776_10500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC776_10505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JC776_10510	COG4837	Protein of unknown function (DUF1462)
JC776_10525	COG3655	Transcriptional regulator
JC776_10535	COG2824	Alkylphosphonate utilization operon protein PhnA
JC776_10540	COG1252	NADH dehydrogenase
JC776_10550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC776_10555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JC776_10560	COG0316	Belongs to the HesB IscA family
JC776_10585	COG1131	(ABC) transporter
JC776_10620	COG1683	Conserved Protein
JC776_10635	COG0492	ferredoxin-NADP+ reductase activity
JC776_10640	COG1252	NADH dehydrogenase
JC776_10660	COG3584	3D domain protein
JC776_10670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JC776_10680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JC776_10685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JC776_10690	COG1268	BioY protein
JC776_10700	COG2050	protein possibly involved in aromatic compounds catabolism
JC776_10720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JC776_10725	COG5018	Exonuclease
JC776_10745	COG2032	superoxide dismutase activity
JC776_10750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JC776_10760	COG2267	carboxylic ester hydrolase activity
JC776_10765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JC776_10770	COG1522	sequence-specific DNA binding
JC776_10775	COG0436	Aminotransferase
JC776_10780	COG1098	S1 RNA binding domain
JC776_10785	COG2155	Conserved Protein
JC776_10790	COG0166	Belongs to the GPI family
JC776_10800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JC776_10805	COG1285	pathogenesis
JC776_10840	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC776_10940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JC776_10945	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JC776_10950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JC776_10955	COG0297	glycogen (starch) synthase activity
JC776_10960	COG0058	SHG alpha-glucan phosphorylase activity
JC776_10980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JC776_10985	COG1575	Belongs to the MenA family. Type 1 subfamily
JC776_10990	COG1169	isochorismate synthase
JC776_10995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JC776_11000	COG0596	Alpha beta hydrolase
JC776_11005	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JC776_11010	COG0318	PFAM AMP-dependent synthetase and ligase
JC776_11015	COG4948	Mandelate Racemase Muconate Lactonizing
JC776_11030	COG0577	efflux transmembrane transporter activity
JC776_11035	COG1136	(ABC) transporter
JC776_11040	COG0577	efflux transmembrane transporter activity
JC776_11045	COG2205	protein histidine kinase activity
JC776_11050	COG0745	RESPONSE REGULATOR receiver
JC776_11060	COG1136	(ABC) transporter
JC776_11065	COG1597	lipid kinase activity
JC776_11070	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JC776_11110	COG1842	Phage shock protein A
JC776_11140	COG1294	oxidase, subunit
JC776_11145	COG1271	oxidase subunit
JC776_11150	COG0288	reversible hydration of carbon dioxide
JC776_11155	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JC776_11160	COG1854	S-ribosylhomocysteine lyase activity
JC776_11170	COG0494	nUDIX hydrolase
JC776_11185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC776_11190	COG1116	anion transmembrane transporter activity
JC776_11195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JC776_11210	COG1368	sulfuric ester hydrolase activity
JC776_11220	COG3409	Peptidoglycan-binding domain 1 protein
JC776_11220	COG5632	N-Acetylmuramoyl-L-alanine amidase
JC776_11225	COG1414	Transcriptional regulator
JC776_11230	COG0246	Mannitol dehydrogenase
JC776_11235	COG1312	Catalyzes the dehydration of D-mannonate
JC776_11240	COG2610	gluconate transmembrane transporter activity
JC776_11245	COG0800	Aldolase
JC776_11295	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JC776_11300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JC776_11325	COG0746	molybdenum cofactor guanylyltransferase activity
JC776_11335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JC776_11340	COG2267	carboxylic ester hydrolase activity
JC776_11350	COG2378	regulation of single-species biofilm formation
JC776_11360	COG1794	racemase activity, acting on amino acids and derivatives
JC776_11370	COG1121	(ABC) transporter
JC776_11375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JC776_11380	COG1242	4 iron, 4 sulfur cluster binding
JC776_11395	COG0346	lactoylglutathione lyase activity
JC776_11400	COG1136	(ABC) transporter
JC776_11410	COG2814	Major facilitator Superfamily
JC776_11415	COG0495	leucyl-tRNA aminoacylation
JC776_11450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JC776_11460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JC776_11475	COG2181	nitrate reductase activity
JC776_11480	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JC776_11485	COG1140	nitrate reductase beta subunit
JC776_11490	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JC776_11495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JC776_11500	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JC776_11505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC776_11510	COG0315	cyclic pyranopterin monophosphate synthase activity
JC776_11515	COG0303	'Molybdopterin
JC776_11520	COG1763	Mo-molybdopterin cofactor biosynthetic process
JC776_11525	COG0314	molybdopterin synthase activity
JC776_11535	COG2223	nitrite transmembrane transporter activity
JC776_11545	COG1329	Transcriptional regulator
JC776_11565	COG3832	glyoxalase III activity
JC776_11575	COG2814	Major facilitator Superfamily
JC776_11580	COG2081	HI0933 family
JC776_11585	COG2244	polysaccharide biosynthetic process
JC776_11590	COG1187	pseudouridine synthase activity
JC776_11595	COG1349	DNA-binding transcription factor activity
JC776_11600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JC776_11610	COG1523	belongs to the glycosyl hydrolase 13 family
JC776_11615	COG0510	thiamine kinase activity
JC776_11625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JC776_11630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC776_11640	COG1363	Peptidase, m42
JC776_11660	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JC776_11665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC776_11670	COG4848	Belongs to the UPF0354 family
JC776_11675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC776_11685	COG1674	ftsk spoiiie
JC776_11695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JC776_11710	COG2309	aminopeptidase activity
JC776_11720	COG3118	belongs to the thioredoxin family
JC776_11725	COG1605	Chorismate mutase
JC776_11725	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JC776_11730	COG1609	Transcriptional regulator
JC776_11740	COG1970	mechanosensitive ion channel activity
JC776_11745	COG0123	including yeast histone deacetylase and acetoin utilization protein
JC776_11750	COG0517	IMP dehydrogenase activity
JC776_11755	COG0454	-acetyltransferase
JC776_11760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JC776_11795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JC776_11800	COG0626	cystathionine gamma-synthase activity
JC776_11805	COG1956	GAF domain-containing protein
JC776_11810	COG1309	transcriptional regulator
JC776_11815	COG0697	spore germination
JC776_11820	COG0583	DNA-binding transcription factor activity
JC776_11825	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JC776_11830	COG1104	cysteine desulfurase activity
JC776_11835	COG0301	tRNA thio-modification
JC776_11845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JC776_11850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JC776_11865	COG3874	Sporulation protein YtfJ
JC776_11870	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JC776_11875	COG0827	DNA restriction-modification system
JC776_11880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JC776_11890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC776_11900	COG0137	argininosuccinate synthase activity
JC776_11905	COG0165	Argininosuccinate lyase
JC776_11925	COG0589	response to stress
JC776_11930	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_11955	COG0006	proline dipeptidase activity
JC776_11960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JC776_11965	COG4109	DRTGG domain
JC776_11975	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JC776_11990	COG0587	DNA-directed DNA polymerase activity
JC776_11995	COG0281	malic enzyme
JC776_12000	COG1725	Transcriptional regulator
JC776_12005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JC776_12010	COG0825	malonyl-CoA metabolic process
JC776_12015	COG0205	6-phosphofructokinase activity
JC776_12025	COG3030	protein affecting phage T7 exclusion by the F plasmid
JC776_12030	COG0628	permease
JC776_12035	COG2707	UPF0756 membrane protein
JC776_12040	COG0372	Belongs to the citrate synthase family
JC776_12045	COG0538	isocitrate dehydrogenase activity
JC776_12050	COG0039	L-malate dehydrogenase activity
JC776_12065	COG0745	RESPONSE REGULATOR receiver
JC776_12070	COG5002	protein histidine kinase activity
JC776_12075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC776_12075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC776_12085	COG1971	Probably functions as a manganese efflux pump
JC776_12095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JC776_12100	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JC776_12105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JC776_12110	COG3611	Membrane attachment protein
JC776_12115	COG1484	DNA-dependent DNA replication
JC776_12125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JC776_12135	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JC776_12140	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JC776_12150	COG1363	Peptidase, m42
JC776_12155	COG1309	transcriptional regulator
JC776_12160	COG1566	PFAM secretion protein HlyD family protein
JC776_12165	COG2814	Major facilitator Superfamily
JC776_12175	COG1418	mRNA catabolic process
JC776_12185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JC776_12190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JC776_12200	COG0017	Asparaginyl-tRNA synthetase
JC776_12210	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JC776_12215	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JC776_12220	COG1286	toxin biosynthetic process
JC776_12225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JC776_12225	COG1796	DNA polymerase
JC776_12230	COG1193	negative regulation of DNA recombination
JC776_12235	COG1187	pseudouridine synthase activity
JC776_12240	COG1114	Component of the transport system for branched-chain amino acids
JC776_12245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JC776_12250	COG4895	conserved protein (DUF2196)
JC776_12260	COG0745	RESPONSE REGULATOR receiver
JC776_12265	COG2205	protein histidine kinase activity
JC776_12270	COG1131	(ABC) transporter
JC776_12290	COG2318	DinB family
JC776_12300	COG0318	PFAM AMP-dependent synthetase and ligase
JC776_12305	COG1309	transcriptional regulator
JC776_12310	COG1024	Enoyl-CoA hydratase
JC776_12315	COG2086	electron transfer activity
JC776_12320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JC776_12325	COG3118	belongs to the thioredoxin family
JC776_12340	COG1719	4-vinyl reductase, 4VR
JC776_12345	COG2009	succinate dehydrogenase
JC776_12350	COG1053	succinate dehydrogenase
JC776_12355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JC776_12365	COG1876	peptidase activity
JC776_12370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JC776_12375	COG1360	Flagellar Motor Protein
JC776_12380	COG4152	abc transporter atp-binding protein
JC776_12385	COG1668	transmembrane transport
JC776_12390	COG1959	2 iron, 2 sulfur cluster binding
JC776_12400	COG2197	response regulator
JC776_12410	COG5401	PFAM Sporulation and spore germination
JC776_12415	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JC776_12425	COG0622	Phosphoesterase
JC776_12485	COG1309	transcriptional regulator
JC776_12495	COG1033	growth of symbiont in host cell
JC776_12495	COG2409	Drug exporters of the RND superfamily
JC776_12510	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_12510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JC776_12510	COG4221	oxidoreductase activity
JC776_12510	COG3321	synthase
JC776_12535	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC776_12540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JC776_12545	COG0470	DNA polymerase III
JC776_12545	COG1067	ATP-dependent peptidase activity
JC776_12555	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JC776_12560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JC776_12565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JC776_12570	COG0181	hydroxymethylbilane synthase activity
JC776_12575	COG1587	Uroporphyrinogen-III synthase
JC776_12580	COG0113	porphobilinogen synthase activity
JC776_12585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JC776_12590	COG1388	LysM domain
JC776_12590	COG1388	LysM domain
JC776_12610	COG0285	dihydrofolate synthase activity
JC776_12620	COG0424	maF-like protein
JC776_12640	COG1077	Cell shape determining protein MreB Mrl
JC776_12645	COG1792	Involved in formation and maintenance of cell shape
JC776_12655	COG0850	regulation of cytokinetic process
JC776_12660	COG2894	cell division
JC776_12665	COG0739	heme binding
JC776_12670	COG1994	Peptidase M50
JC776_12675	COG1530	ribonuclease E activity
JC776_12680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JC776_12685	COG2868	ribosomal protein
JC776_12690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JC776_12695	COG3290	protein histidine kinase activity
JC776_12705	COG0745	RESPONSE REGULATOR receiver
JC776_12710	COG5002	protein histidine kinase activity
JC776_12715	COG1136	(ABC) transporter
JC776_12720	COG0577	efflux transmembrane transporter activity
JC776_12725	COG0577	efflux transmembrane transporter activity
JC776_12730	COG0077	Prephenate dehydratase
JC776_12735	COG2258	MOSC domain
JC776_12740	COG1827	regulation of RNA biosynthetic process
JC776_12745	COG1104	cysteine desulfurase activity
JC776_12750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JC776_12755	COG0157	Belongs to the NadC ModD family
JC776_12760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JC776_12780	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JC776_12785	COG0632	four-way junction helicase activity
JC776_12790	COG2255	four-way junction helicase activity
JC776_12800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JC776_12805	COG0343	queuine tRNA-ribosyltransferase activity
JC776_12810	COG1862	Preprotein translocase
JC776_12830	COG2244	polysaccharide biosynthetic process
JC776_12840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JC776_12840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JC776_12845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JC776_12850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JC776_12850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JC776_12855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JC776_12860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JC776_12865	COG1490	D-aminoacyl-tRNA deacylase activity
JC776_12885	COG0124	histidyl-tRNA synthetase
JC776_12890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JC776_12895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JC776_12905	COG2207	Transcriptional regulator
JC776_12925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JC776_12930	COG1959	2 iron, 2 sulfur cluster binding
JC776_12935	COG1104	cysteine desulfurase activity
JC776_12940	COG0482	sulfurtransferase activity
JC776_12950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JC776_12970	COG0628	permease
JC776_12975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JC776_12980	COG4472	Bacterial protein of unknown function (DUF965)
JC776_12985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JC776_12995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JC776_13000	COG4122	O-methyltransferase activity
JC776_13005	COG0826	peptidase U32
JC776_13010	COG0826	peptidase U32
JC776_13015	COG0572	uridine kinase
JC776_13020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JC776_13030	COG0768	penicillin binding
JC776_13045	COG2226	methyltransferase
JC776_13050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JC776_13055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JC776_13060	COG0626	cystathionine gamma-synthase activity
JC776_13070	COG1609	Transcriptional regulator
JC776_13090	COG2259	Doxx family
JC776_13095	COG2514	catechol 2,3-dioxygenase activity
JC776_13100	COG2154	pterin-4-alpha-carbinolamine dehydratase
JC776_13105	COG3186	Phenylalanine-4-hydroxylase
JC776_13130	COG2267	carboxylic ester hydrolase activity
JC776_13135	COG0456	acetyltransferase
JC776_13140	COG1785	Belongs to the alkaline phosphatase family
JC776_13145	COG2357	RelA SpoT domain protein
JC776_13150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JC776_13165	COG0688	phosphatidylethanolamine metabolic process
JC776_13175	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JC776_13180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JC776_13185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JC776_13190	COG1534	Rna-binding protein
JC776_13195	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JC776_13200	COG1713	HD superfamily hydrolase involved in NAD metabolism
JC776_13205	COG0799	negative regulation of ribosome biogenesis
JC776_13210	COG2226	methyltransferase
JC776_13215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JC776_13220	COG1555	photosystem II stabilization
JC776_13220	COG1596	polysaccharide export
JC776_13225	COG2131	deaminase
JC776_13230	COG0658	competence protein
JC776_13230	COG2333	competence protein COMEC
JC776_13240	COG1466	dna polymerase III delta subunit
JC776_13245	COG0268	Binds directly to 16S ribosomal RNA
JC776_13250	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JC776_13260	COG0481	GTPase activity
JC776_13265	COG0693	protein deglycase activity
JC776_13270	COG1733	regulation of RNA biosynthetic process
JC776_13275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JC776_13280	COG1420	regulation of RNA biosynthetic process
JC776_13285	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JC776_13290	COG0443	Heat shock 70 kDa protein
JC776_13295	COG0484	heat shock protein binding
JC776_13300	COG2264	protein methyltransferase activity
JC776_13305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JC776_13310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JC776_13315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JC776_13320	COG1610	YqeY-like protein
JC776_13335	COG1702	phosphate starvation-inducible protein PhoH
JC776_13340	COG1480	7TM receptor with intracellular HD hydrolase
JC776_13345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JC776_13350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JC776_13360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JC776_13370	COG1381	Involved in DNA repair and RecF pathway recombination
JC776_13375	COG0517	IMP dehydrogenase activity
JC776_13380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JC776_13385	COG1671	Belongs to the UPF0178 family
JC776_13390	COG0358	DNA primase activity
JC776_13395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JC776_13405	COG2384	SAM-dependent methyltransferase
JC776_13410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JC776_13415	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JC776_13430	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JC776_13440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC776_13445	COG1121	(ABC) transporter
JC776_13450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JC776_13455	COG0735	belongs to the Fur family
JC776_13460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JC776_13480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JC776_13485	COG0477	Major facilitator Superfamily
JC776_13490	COG0768	penicillin binding
JC776_13495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JC776_13500	COG0573	inorganic phosphate transmembrane transporter activity
JC776_13505	COG0581	inorganic phosphate transmembrane transporter activity
JC776_13515	COG0704	Plays a role in the regulation of phosphate uptake
JC776_13520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JC776_13525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JC776_13530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JC776_13535	COG4483	Protein conserved in bacteria
JC776_13540	COG1940	carbohydrate kinase activity
JC776_13550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC776_13565	COG0626	cystathionine gamma-synthase activity
JC776_13570	COG0626	cystathionine gamma-synthase activity
JC776_13575	COG0646	methionine synthase
JC776_13575	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JC776_13580	COG0646	methionine synthase
JC776_13580	COG1410	methionine synthase
JC776_13595	COG1078	dGTPase activity
JC776_13640	COG1396	sequence-specific DNA binding
JC776_13780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JC776_13800	COG3728	DNA packaging
JC776_13880	COG4824	toxin secretion phage lysis holin
JC776_13910	COG1459	type II secretion system
JC776_13935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JC776_13965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JC776_13970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JC776_13975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JC776_13980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JC776_13995	COG1725	Transcriptional regulator
JC776_14000	COG1131	(ABC) transporter
JC776_14020	COG2076	Multidrug Resistance protein
JC776_14025	COG2076	Multidrug Resistance protein
JC776_14035	COG1609	Transcriptional regulator
JC776_14045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JC776_14060	COG1321	iron dependent repressor
JC776_14070	COG3872	metal-dependent enzyme
JC776_14080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JC776_14085	COG0006	proline dipeptidase activity
JC776_14090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JC776_14110	COG3854	ATPases associated with a variety of cellular activities
JC776_14155	COG0511	ligase activity, forming carbon-carbon bonds
JC776_14160	COG0439	Biotin carboxylase
JC776_14165	COG1302	Protein conserved in bacteria
JC776_14170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JC776_14175	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JC776_14180	COG1570	exodeoxyribonuclease VII activity
JC776_14185	COG1722	exodeoxyribonuclease VII activity
JC776_14195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JC776_14200	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JC776_14210	COG0497	DNA recombination
JC776_14215	COG0750	zinc metalloprotease
JC776_14220	COG0745	RESPONSE REGULATOR receiver
JC776_14225	COG3093	addiction module antidote protein HigA
JC776_14230	COG0584	glycerophosphoryl diester phosphodiesterase
JC776_14240	COG3829	transcription factor binding
JC776_14240	COG3290	protein histidine kinase activity
JC776_14245	COG0280	phosphate acetyltransferase
JC776_14255	COG3426	butyrate kinase activity
JC776_14260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JC776_14265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JC776_14270	COG0022	dehydrogenase e1 component
JC776_14275	COG0508	dehydrogenase complex catalyzes the overall conversion of
JC776_14280	COG0772	Belongs to the SEDS family
JC776_14285	COG2816	NAD+ diphosphatase activity
JC776_14300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC776_14305	COG0765	amino acid transport
JC776_14310	COG1126	abc transporter atp-binding protein
JC776_14315	COG4129	membrane
JC776_14320	COG1376	ErfK ybiS ycfS ynhG family protein
JC776_14335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC776_14340	COG2195	Cleaves the N-terminal amino acid of tripeptides
JC776_14360	COG1234	tRNA 3'-trailer cleavage
JC776_14370	COG1760	l-serine dehydratase
JC776_14375	COG1760	l-serine dehydratase
JC776_14380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JC776_14385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC776_14390	COG0300	oxidoreductase activity
JC776_14400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JC776_14410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JC776_14440	COG0737	Belongs to the 5'-nucleotidase family
JC776_14445	COG1757	Na H antiporter
JC776_14455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JC776_14465	COG0156	8-amino-7-oxononanoate synthase activity
JC776_14470	COG0596	Alpha beta hydrolase
JC776_14475	COG4106	trans-aconitate 2-methyltransferase activity
JC776_14480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JC776_14495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JC776_14495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JC776_14500	COG0307	riboflavin synthase, alpha
JC776_14505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JC776_14505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JC776_14520	COG1073	alpha beta
JC776_14525	COG0456	acetyltransferase
JC776_14530	COG1609	Transcriptional regulator
JC776_14535	COG2056	Na+-H+ antiporter family
JC776_14540	COG0596	Alpha beta hydrolase
JC776_14550	COG4085	toxin activity
JC776_14550	COG1525	nuclease
JC776_14550	COG0737	Belongs to the 5'-nucleotidase family
JC776_14560	COG0456	acetyltransferase
JC776_14560	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JC776_14565	COG0656	L-ascorbic acid biosynthetic process
JC776_14570	COG0667	Aldo Keto reductase
JC776_14590	COG1300	Membrane
JC776_14595	COG0735	belongs to the Fur family
JC776_14605	COG4974	Belongs to the 'phage' integrase family
JC776_14630	COG0598	Magnesium transport protein CorA
JC776_14645	COG1846	Transcriptional regulator
JC776_14665	COG1131	(ABC) transporter
JC776_14670	COG1725	Transcriptional regulator
JC776_14675	COG1686	Belongs to the peptidase S11 family
JC776_14685	COG2172	sigma factor antagonist activity
JC776_14695	COG0733	neurotransmitter:sodium symporter activity
JC776_14720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JC776_14735	COG0697	spore germination
JC776_14740	COG0561	phosphatase activity
JC776_14745	COG4086	secreted protein
JC776_14750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JC776_14760	COG1547	Domain of unknown function (DUF309)
JC776_14770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JC776_14775	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JC776_14790	COG0363	glucosamine-6-phosphate deaminase activity
JC776_14795	COG2188	Transcriptional regulator
JC776_14805	COG3711	transcriptional antiterminator
JC776_14810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC776_14810	COG2190	(PTS) system
JC776_14810	COG1263	PTS System
JC776_14835	COG0778	Nitroreductase
JC776_14840	COG2199	diguanylate cyclase activity
JC776_14850	COG2084	Dehydrogenase
JC776_14865	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JC776_14870	COG0235	Class ii aldolase
JC776_14875	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JC776_14880	COG1850	ribulose-bisphosphate carboxylase activity
JC776_14885	COG0436	Aminotransferase
JC776_14890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JC776_14895	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JC776_14900	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JC776_14910	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_14915	COG1695	Transcriptional regulator
JC776_14940	COG0183	Belongs to the thiolase family
JC776_14965	COG3842	ATPase activity
JC776_14970	COG0366	Alpha amylase catalytic
JC776_14980	COG2182	Extracellular solute-binding protein
JC776_14985	COG1175	transmembrane transport
JC776_14990	COG3833	ABC-type maltose transport systems, permease component
JC776_14995	COG1609	Transcriptional regulator
JC776_15000	COG0436	Aminotransferase
JC776_15010	COG2205	protein histidine kinase activity
JC776_15020	COG3209	COG3209 Rhs family protein
JC776_15030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JC776_15035	COG2814	Major facilitator Superfamily
JC776_15075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JC776_15085	COG1408	metallophosphoesterase
JC776_15090	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_15095	COG2200	EAL domain
JC776_15110	COG4703	Protein of unknown function (DUF1797)
JC776_15115	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JC776_15125	COG0517	IMP dehydrogenase activity
JC776_15130	COG0583	DNA-binding transcription factor activity
JC776_15135	COG2171	N-acyltransferase activity
JC776_15140	COG1473	amidohydrolase
JC776_15150	COG0569	domain protein
JC776_15155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JC776_15160	COG5503	Protein of unknown function (DUF1447)
JC776_15165	COG0561	phosphatase activity
JC776_15180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JC776_15190	COG0508	dehydrogenase complex catalyzes the overall conversion of
JC776_15230	COG1982	Orn Lys Arg decarboxylase major
JC776_15235	COG4476	Belongs to the UPF0223 family
JC776_15240	COG4493	Belongs to the UPF0637 family
JC776_15250	COG0483	inositol monophosphate 1-phosphatase activity
JC776_15260	COG1217	gtp-binding protein TYPA
JC776_15275	COG4896	Protein conserved in bacteria
JC776_15285	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JC776_15290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JC776_15295	COG4838	Belongs to the UPF0358 family
JC776_15300	COG0772	Belongs to the SEDS family
JC776_15305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JC776_15310	COG1612	heme a metabolic process
JC776_15315	COG0109	protoheme IX farnesyltransferase activity
JC776_15325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JC776_15340	COG3336	cytochrome c oxidase
JC776_15350	COG2340	Cysteine-rich secretory protein family
JC776_15365	COG0406	alpha-ribazole phosphatase activity
JC776_15370	COG3679	Belongs to the UPF0342 family
JC776_15375	COG4471	UPF0298 protein
JC776_15385	COG0742	ribosomal rna small subunit methyltransferase
JC776_15390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JC776_15395	COG3314	Sporulation integral membrane protein YlbJ
JC776_15400	COG1752	Esterase of the alpha-beta hydrolase superfamily
JC776_15405	COG3480	Lon protease (S16) C-terminal proteolytic domain
JC776_15410	COG1323	Belongs to the UPF0348 family
JC776_15415	COG0582	viral genome integration into host DNA
JC776_15465	COG5377	YqaJ viral recombinase family
JC776_15475	COG3723	Recombinational DNA repair protein, rece pathway
JC776_15510	COG0756	dUTP diphosphatase activity
JC776_15600	COG4626	Terminase
JC776_15600	COG1802	Transcriptional regulator
JC776_15710	COG1399	metal-binding, possibly nucleic acid-binding protein
JC776_15715	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JC776_15725	COG0454	-acetyltransferase
JC776_15730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JC776_15735	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JC776_15740	COG0275	rRNA processing
JC776_15745	COG4839	cell division protein FtsL
JC776_15750	COG0768	penicillin binding
JC776_15755	COG0768	penicillin binding
JC776_15760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JC776_15765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JC776_15770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JC776_15775	COG0772	Belongs to the SEDS family
JC776_15780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JC776_15790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JC776_15795	COG0849	cell division
JC776_15800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JC776_15810	COG1191	sigma factor activity
JC776_15815	COG1191	sigma factor activity
JC776_15820	COG1873	PFAM PRC-barrel domain
JC776_15830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JC776_15835	COG1799	cell septum assembly
JC776_15840	COG0762	integral membrane protein
JC776_15845	COG2302	S4 RNA-binding domain
JC776_15850	COG3599	regulation of cell shape
JC776_15855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JC776_15865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JC776_15870	COG0564	pseudouridine synthase activity
JC776_15875	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JC776_15885	COG0540	Belongs to the ATCase OTCase family
JC776_15890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JC776_15900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JC776_15905	COG0543	2 iron, 2 sulfur cluster binding
JC776_15910	COG0167	dihydroorotate dehydrogenase activity
JC776_15915	COG0284	orotidine-5'-phosphate decarboxylase activity
JC776_15920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JC776_15945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JC776_15950	COG1561	YicC-like family, N-terminal region
JC776_15965	COG1758	RNA polymerase activity
JC776_15970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JC776_15975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JC776_15980	COG0242	peptide deformylase activity
JC776_15985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JC776_15990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JC776_15990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JC776_15995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JC776_16000	COG0631	protein serine/threonine phosphatase activity
JC776_16005	COG2815	serine threonine protein kinase
JC776_16005	COG0515	serine threonine protein kinase
JC776_16010	COG1162	GTPase activity
JC776_16015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JC776_16020	COG1564	THIamine pyrophosphokinase
JC776_16030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JC776_16035	COG1302	Protein conserved in bacteria
JC776_16040	COG1461	Dihydroxyacetone kinase
JC776_16045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JC776_16050	COG1349	DNA-binding transcription factor activity
JC776_16050	COG2050	protein possibly involved in aromatic compounds catabolism
JC776_16055	COG0416	fatty acid biosynthetic process
JC776_16060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JC776_16065	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_16070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JC776_16075	COG0571	ribonuclease III activity
JC776_16080	COG1196	nuclear chromosome segregation
JC776_16085	COG0552	protein localization to endoplasmic reticulum
JC776_16090	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JC776_16095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JC776_16100	COG0228	four-way junction DNA binding
JC776_16105	COG1837	Belongs to the UPF0109 family
JC776_16110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JC776_16115	COG0336	Belongs to the RNA methyltransferase TrmD family
JC776_16120	COG0335	large ribosomal subunit rRNA binding
JC776_16135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JC776_16140	COG0045	succinate-CoA ligase (ADP-forming) activity
JC776_16145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JC776_16150	COG0758	DNA mediated transformation
JC776_16155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JC776_16160	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JC776_16165	COG4974	Belongs to the 'phage' integrase family
JC776_16170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JC776_16175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JC776_16180	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JC776_16185	COG0052	Belongs to the universal ribosomal protein uS2 family
JC776_16190	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JC776_16195	COG0528	UMP kinase activity
JC776_16200	COG0233	cytoplasmic translational termination
JC776_16210	COG4589	Belongs to the CDS family
JC776_16220	COG0750	zinc metalloprotease
JC776_16225	COG0442	prolyl-tRNA aminoacylation
JC776_16235	COG0779	Required for maturation of 30S ribosomal subunits
JC776_16240	COG0195	Participates in both transcription termination and antitermination
JC776_16245	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JC776_16250	COG1358	cellular component organization or biogenesis
JC776_16255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JC776_16260	COG1550	Protein conserved in bacteria
JC776_16265	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JC776_16270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JC776_16275	COG0196	riboflavin kinase activity
JC776_16285	COG1185	polyribonucleotide nucleotidyltransferase activity
JC776_16290	COG0726	polysaccharide deacetylase
JC776_16295	COG0612	Peptidase, M16
JC776_16300	COG1873	PFAM PRC-barrel domain
JC776_16305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JC776_16310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JC776_16315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JC776_16320	COG0527	aspartate kinase activity
JC776_16335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JC776_16360	COG0740	serine-type endopeptidase activity
JC776_16385	COG2188	Transcriptional regulator
JC776_16390	COG1744	ABC transporter substrate-binding protein PnrA-like
JC776_16395	COG3845	ABC transporter
JC776_16400	COG4603	Belongs to the binding-protein-dependent transport system permease family
JC776_16405	COG1079	Belongs to the binding-protein-dependent transport system permease family
JC776_16410	COG0612	Peptidase, M16
JC776_16415	COG0612	Peptidase, M16
JC776_16420	COG0300	oxidoreductase activity
JC776_16435	COG1426	Protein conserved in bacteria
JC776_16440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JC776_16445	COG1546	Belongs to the CinA family
JC776_16445	COG1058	Belongs to the CinA family
JC776_16450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JC776_16455	COG1418	mRNA catabolic process
JC776_16460	COG1692	metallophosphoesterase
JC776_16465	COG2359	stage V sporulation protein S
JC776_16475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JC776_16475	COG0674	pyruvate-flavodoxin oxidoreductase activity
JC776_16480	COG1013	pyruvate-flavodoxin oxidoreductase activity
JC776_16490	COG2318	DinB family
JC776_16495	COG0322	excinuclease ABC activity
JC776_16500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC776_16520	COG0201	protein transport
JC776_16525	COG0693	protein deglycase activity
JC776_16545	COG2002	toxin-antitoxin pair type II binding
JC776_16550	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_16560	COG1309	transcriptional regulator
JC776_16580	COG0475	glutathione-regulated potassium exporter activity
JC776_16600	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_16610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JC776_16630	COG0789	Transcriptional regulator
JC776_16660	COG5002	protein histidine kinase activity
JC776_16665	COG1686	Belongs to the peptidase S11 family
JC776_16670	COG0640	Transcriptional regulator
JC776_16675	COG1216	Glycosyl transferase, family 2
JC776_16685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JC776_16690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JC776_16695	COG1024	Enoyl-CoA hydratase
JC776_16700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JC776_16705	COG0511	ligase activity, forming carbon-carbon bonds
JC776_16710	COG0439	Biotin carboxylase
JC776_16715	COG1960	acyl-CoA dehydrogenase activity
JC776_16725	COG2195	Cleaves the N-terminal amino acid of tripeptides
JC776_16755	COG0588	phosphoglycerate mutase activity
JC776_16775	COG2971	BadF BadG BcrA BcrD
JC776_16795	COG1649	PFAM Uncharacterised BCR, COG1649
JC776_16820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JC776_16825	COG1132	(ABC) transporter
JC776_16830	COG1132	(ABC) transporter
JC776_16840	COG0010	Belongs to the arginase family
JC776_16860	COG0667	Aldo Keto reductase
JC776_16865	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JC776_16870	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JC776_16905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JC776_16910	COG2329	Antibiotic biosynthesis monooxygenase
JC776_16925	COG0776	regulation of translation
JC776_16940	COG2814	Major facilitator Superfamily
JC776_16945	COG3251	PFAM MbtH domain protein
JC776_16950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JC776_16955	COG1535	isochorismatase
JC776_16955	COG3433	isochorismatase activity
JC776_16960	COG1021	2,3-dihydroxybenzoate-AMP ligase
JC776_16965	COG1169	isochorismate synthase
JC776_16970	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_17000	COG0457	Tetratricopeptide repeat
JC776_17025	COG1942	4-Oxalocrotonate Tautomerase
JC776_17045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JC776_17050	COG1131	(ABC) transporter
JC776_17070	COG1131	(ABC) transporter
JC776_17075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JC776_17105	COG3104	oligopeptide transport
JC776_17110	COG0419	ATPase involved in DNA repair
JC776_17115	COG0420	3'-5' exonuclease activity
JC776_17135	COG1280	lysine exporter protein (LysE YggA)
JC776_17145	COG1012	belongs to the aldehyde dehydrogenase family
JC776_17150	COG2084	Dehydrogenase
JC776_17155	COG1960	acyl-CoA dehydrogenase activity
JC776_17160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JC776_17165	COG2079	MmgE PrpD family protein
JC776_17170	COG0372	Belongs to the citrate synthase family
JC776_17180	COG4499	WXG100 protein secretion system (Wss), protein YukC
JC776_17180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC776_17205	COG3403	YqcI/YcgG family
JC776_17210	COG1280	lysine exporter protein (LysE YggA)
JC776_17225	COG0671	phosphoesterase, PA-phosphatase related
JC776_17230	COG2323	membrane
JC776_17235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JC776_17240	COG1408	metallophosphoesterase
JC776_17245	COG0726	polysaccharide deacetylase
JC776_17255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JC776_17295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC776_17300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JC776_17305	COG0671	phosphoesterase, PA-phosphatase related
JC776_17310	COG1357	PFAM Pentapeptide repeats (8 copies)
JC776_17310	COG0515	serine threonine protein kinase
JC776_17335	COG4479	Belongs to the UPF0346 family
JC776_17345	COG1509	lysine 2,3-aminomutase activity
JC776_17350	COG3829	transcription factor binding
JC776_17355	COG0456	acetyltransferase
JC776_17360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JC776_17365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JC776_17370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JC776_17375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JC776_17395	COG5506	Protein of unknown function (DUF1694)
JC776_17400	COG1253	flavin adenine dinucleotide binding
JC776_17410	COG1151	hydroxylamine reductase activity
JC776_17465	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JC776_17475	COG1070	Carbohydrate kinase
JC776_17480	COG1737	Transcriptional regulator
JC776_17490	COG0071	Belongs to the small heat shock protein (HSP20) family
JC776_17510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JC776_17520	COG0367	asparagine synthase
JC776_17525	COG0071	Belongs to the small heat shock protein (HSP20) family
JC776_17530	COG1999	signal sequence binding
JC776_17540	COG1307	EDD domain protein, DegV family
JC776_17550	COG0805	protein transport
JC776_17555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JC776_17560	COG1272	protein, Hemolysin III
JC776_17565	COG0204	Acyl-transferase
JC776_17575	COG0768	penicillin binding
JC776_17585	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JC776_17590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JC776_17605	COG4473	ABC transporter
JC776_17610	COG1131	(ABC) transporter
JC776_17620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JC776_17625	COG0456	acetyltransferase
JC776_17635	COG2610	gluconate transmembrane transporter activity
JC776_17655	COG0477	Major facilitator Superfamily
JC776_17660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC776_17670	COG0596	Alpha beta hydrolase
JC776_17675	COG0733	neurotransmitter:sodium symporter activity
JC776_17685	COG0018	arginyl-trna synthetase
JC776_17690	COG2521	methyltransferase
JC776_17690	COG2136	Putative SAM-dependent methyltransferase
JC776_17705	COG1413	lyase activity
JC776_17710	COG0629	single-stranded DNA binding
JC776_17720	COG0488	(ABC) transporter
JC776_17725	COG1418	mRNA catabolic process
JC776_17765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JC776_17770	COG0798	PFAM Bile acid sodium symporter
JC776_17775	COG0640	Transcriptional regulator
JC776_17795	COG0386	Belongs to the glutathione peroxidase family
JC776_17820	COG2226	methyltransferase
JC776_17845	COG3874	Sporulation protein YtfJ
JC776_17900	COG4499	WXG100 protein secretion system (Wss), protein YukC
JC776_17950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC776_17955	COG1819	glycosyl
JC776_17960	COG1819	glycosyl
JC776_17965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JC776_18015	COG1876	peptidase activity
JC776_18025	COG0860	N-Acetylmuramoyl-L-alanine amidase
JC776_18060	COG3023	N-Acetylmuramoyl-L-alanine amidase
JC776_18085	COG0534	Mate efflux family protein
JC776_18100	COG2826	transposase and inactivated derivatives, IS30 family
JC776_18165	COG0457	Tetratricopeptide repeat
JC776_18190	COG0318	PFAM AMP-dependent synthetase and ligase
JC776_18195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JC776_18235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JC776_18245	COG3655	Transcriptional regulator
JC776_18250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC776_18280	COG0824	Thioesterase
JC776_18290	COG4841	protein insertion into membrane
JC776_18295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JC776_18310	COG0745	RESPONSE REGULATOR receiver
JC776_18315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JC776_18320	COG1832	CoA-binding protein
JC776_18325	COG0187	DNA topoisomerase II activity
JC776_18330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JC776_18335	COG0673	inositol 2-dehydrogenase activity
JC776_18340	COG1301	dicarboxylic acid transport
JC776_18345	COG4166	transmembrane transport
JC776_18350	COG4166	transmembrane transport
JC776_18355	COG2226	methyltransferase
JC776_18390	COG2962	Rard protein
JC776_18395	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JC776_18400	COG1657	PFAM Prenyltransferase squalene oxidase
JC776_18410	COG1012	belongs to the aldehyde dehydrogenase family
JC776_18415	COG3924	membrane
JC776_18420	COG4145	pantothenate transmembrane transporter activity
JC776_18435	COG3409	Peptidoglycan-binding domain 1 protein
JC776_18450	COG0165	Argininosuccinate lyase
JC776_18455	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_18465	COG1278	Cold shock
JC776_18490	COG0582	viral genome integration into host DNA
JC776_18540	COG1484	DNA-dependent DNA replication
JC776_18655	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JC776_18875	COG2720	vancomycin resistance protein
JC776_18880	COG1285	pathogenesis
JC776_18885	COG0277	FAD linked oxidase domain protein
JC776_18890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JC776_18900	COG3397	chitin binding
JC776_18930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC776_18935	COG0584	glycerophosphoryl diester phosphodiesterase
JC776_18955	COG1164	Oligoendopeptidase f
JC776_18960	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JC776_18965	COG1193	negative regulation of DNA recombination
JC776_18975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JC776_18980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JC776_19060	COG1136	(ABC) transporter
JC776_19060	COG0577	efflux transmembrane transporter activity
JC776_19105	COG0582	viral genome integration into host DNA
JC776_19185	COG3813	Protein conserved in bacteria
JC776_19190	COG0789	Transcriptional regulator
JC776_19195	COG1253	flavin adenine dinucleotide binding
JC776_19205	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JC776_19210	COG0579	oxidoreductase
JC776_19215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC776_19220	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JC776_19260	COG2365	Tyrosine phosphatase family
JC776_19280	COG1131	(ABC) transporter
JC776_19300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JC776_19325	COG1122	ATPase activity
JC776_19355	COG2031	fatty acid transporter
JC776_19365	COG2814	Major facilitator Superfamily
JC776_19370	COG1846	Transcriptional regulator
JC776_19385	COG0477	Major facilitator Superfamily
JC776_19480	COG4851	CamS sex pheromone cAM373 precursor
JC776_19500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JC776_19510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC776_19515	COG0438	transferase activity, transferring glycosyl groups
JC776_19520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC776_19535	COG0438	transferase activity, transferring glycosyl groups
JC776_19540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JC776_19545	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JC776_19550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JC776_19560	COG0346	lactoylglutathione lyase activity
JC776_19575	COG3314	Sporulation integral membrane protein YlbJ
JC776_19585	COG1960	acyl-CoA dehydrogenase activity
JC776_19600	COG1414	Transcriptional regulator
JC776_19605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JC776_19610	COG1984	allophanate hydrolase subunit 2
JC776_19615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JC776_19630	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JC776_19650	COG0833	amino acid
JC776_19660	COG0730	response to heat
JC776_19675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JC776_19685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC776_19690	COG0697	spore germination
JC776_19700	COG0477	Major facilitator Superfamily
JC776_19705	COG0456	acetyltransferase
JC776_19720	COG0494	nUDIX hydrolase
JC776_19745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC776_19760	COG2329	Antibiotic biosynthesis monooxygenase
JC776_19800	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JC776_19830	COG1605	Chorismate mutase
JC776_19830	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JC776_19835	COG0488	(ABC) transporter
JC776_19840	COG1368	sulfuric ester hydrolase activity
JC776_19845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC776_19870	COG0456	acetyltransferase
JC776_19870	COG0454	-acetyltransferase
JC776_19885	COG2746	aminoglycoside 3-N-acetyltransferase activity
JC776_19900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JC776_19905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC776_19910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JC776_19920	COG0628	permease
JC776_19945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC776_19950	COG3973	AAA domain
JC776_19965	COG0436	Aminotransferase
JC776_19995	COG0675	Transposase, IS605 OrfB family
JC776_20000	COG2261	transglycosylase associated protein
JC776_20020	COG5444	nuclease activity
JC776_20105	COG5444	nuclease activity
JC776_20145	COG1307	EDD domain protein, DegV family
JC776_20225	COG4948	Mandelate Racemase Muconate Lactonizing
JC776_20235	COG4166	transmembrane transport
JC776_20280	COG3397	chitin binding
JC776_20290	COG1227	inorganic diphosphatase activity
JC776_20295	COG4637	Psort location Cytoplasmic, score
JC776_20320	COG0514	ATP-dependent DNA helicase (RecQ)
JC776_20355	COG2153	protein acetylation
JC776_20385	COG0517	IMP dehydrogenase activity
JC776_20385	COG4175	Glycine betaine
JC776_20390	COG4176	ABC-type proline glycine betaine transport system permease component
JC776_20400	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_20410	COG3844	kynureninase activity
JC776_20415	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JC776_20445	COG2959	enzyme of heme biosynthesis
JC776_20455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC776_20460	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC776_20465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JC776_20480	COG0010	Belongs to the arginase family
JC776_20485	COG1228	amidohydrolase
JC776_20490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JC776_20495	COG2986	histidine ammonia-lyase
JC776_20515	COG4846	Membrane protein involved in cytochrome C biogenesis
JC776_20520	COG0785	Cytochrome C biogenesis protein
JC776_20535	COG0583	DNA-binding transcription factor activity
JC776_20540	COG1380	Effector of murein hydrolase LrgA
JC776_20545	COG1346	cytolysis
JC776_20550	COG4187	Peptidase family M20/M25/M40
JC776_20560	COG0833	amino acid
JC776_20570	COG0730	response to heat
JC776_20580	COG5632	N-Acetylmuramoyl-L-alanine amidase
JC776_20580	COG3409	Peptidoglycan-binding domain 1 protein
JC776_20595	COG1132	(ABC) transporter
JC776_20600	COG1132	(ABC) transporter
JC776_20605	COG3763	UPF0154 protein
JC776_20620	COG3639	organic phosphonate transmembrane transporter activity
JC776_20625	COG3639	organic phosphonate transmembrane transporter activity
JC776_20640	COG0737	Belongs to the 5'-nucleotidase family
JC776_20645	COG4224	UPF0291 protein
JC776_20650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JC776_20655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JC776_20670	COG1695	Transcriptional regulator
JC776_20710	COG3328	transposase activity
JC776_20715	COG3328	transposase activity
JC776_20720	COG3328	transposase activity
JC776_20735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JC776_20770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC776_20785	COG0730	response to heat
JC776_20830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JC776_20900	COG3723	Recombinational DNA repair protein, rece pathway
JC776_20910	COG5377	YqaJ viral recombinase family
JC776_20960	COG0582	viral genome integration into host DNA
JC776_20965	COG0174	glutamine synthetase
JC776_20970	COG0789	Transcriptional regulator
JC776_20975	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JC776_20980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JC776_20985	COG2860	membrane
JC776_20995	COG0464	growth
JC776_21010	COG1923	regulation of RNA biosynthetic process
JC776_21015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JC776_21025	COG1388	LysM domain
JC776_21025	COG3584	3D domain protein
JC776_21030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC776_21030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC776_21030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC776_21035	COG1105	Belongs to the carbohydrate kinase PfkB family
JC776_21040	COG1349	DNA-binding transcription factor activity
JC776_21045	COG2322	membrane
JC776_21065	COG2116	formate transmembrane transporter activity
JC776_21075	COG1937	Protein conserved in bacteria
JC776_21080	COG2819	hydrolase of the alpha beta superfamily
JC776_21085	COG1120	ATPase activity
JC776_21090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC776_21095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC776_21100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JC776_21105	COG2706	6-phosphogluconolactonase activity
JC776_21110	COG2826	transposase and inactivated derivatives, IS30 family
JC776_21115	COG2195	Cleaves the N-terminal amino acid of tripeptides
JC776_21125	COG0346	lactoylglutathione lyase activity
JC776_21135	COG1113	amino acid transport
JC776_21145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JC776_21160	COG3209	COG3209 Rhs family protein
JC776_21190	COG0484	heat shock protein binding
JC776_21260	COG4191	Histidine kinase
JC776_21265	COG2197	response regulator
JC776_21270	COG1476	TRANSCRIPTIONal
JC776_21445	COG2003	Belongs to the UPF0758 family
JC776_21470	COG4166	transmembrane transport
JC776_21480	COG0457	Tetratricopeptide repeat
JC776_21515	COG1192	Involved in chromosome partitioning
JC776_21675	COG0741	lytic transglycosylase activity
JC776_21675	COG0791	NLP P60 protein
JC776_21795	COG1028	Short-chain dehydrogenase reductase Sdr
JC776_21820	COG0583	DNA-binding transcription factor activity
JC776_21905	COG4974	Belongs to the 'phage' integrase family