locus-tag	class	description
JC774_00030	COG1404	Belongs to the peptidase S8 family
JC774_00040	COG0582	viral genome integration into host DNA
JC774_00065	COG1132	(ABC) transporter
JC774_00185	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JC774_00265	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC774_00305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC774_00310	COG0581	inorganic phosphate transmembrane transporter activity
JC774_00315	COG0573	inorganic phosphate transmembrane transporter activity
JC774_00320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JC774_00325	COG1918	ferrous iron import across plasma membrane
JC774_00325	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JC774_00330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JC774_00335	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JC774_00350	COG0531	amino acid
JC774_00355	COG0697	spore germination
JC774_00360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC774_00375	COG4990	cell redox homeostasis
JC774_00380	COG0833	amino acid
JC774_00385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JC774_00390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JC774_00405	COG0569	domain protein
JC774_00405	COG0475	glutathione-regulated potassium exporter activity
JC774_00415	COG2153	protein acetylation
JC774_00420	COG1113	amino acid transport
JC774_00435	COG1114	Component of the transport system for branched-chain amino acids
JC774_00440	COG3104	oligopeptide transport
JC774_00465	COG1476	TRANSCRIPTIONal
JC774_00470	COG3584	3D domain protein
JC774_00470	COG1388	LysM domain
JC774_00475	COG0840	transmembrane signaling receptor activity
JC774_00500	COG3568	Endonuclease Exonuclease Phosphatase
JC774_00515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JC774_00520	COG1879	ABC-type sugar transport system periplasmic component
JC774_00525	COG1172	Belongs to the binding-protein-dependent transport system permease family
JC774_00535	COG1869	D-ribose catabolic process
JC774_00540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JC774_00545	COG1609	Transcriptional regulator
JC774_00550	COG0477	Major facilitator Superfamily
JC774_00555	COG1846	Transcriptional regulator
JC774_00560	COG2271	Major facilitator Superfamily
JC774_00570	COG4608	Belongs to the ABC transporter superfamily
JC774_00575	COG0601	transmembrane transport
JC774_00585	COG0747	negative chemotaxis
JC774_00595	COG0589	response to stress
JC774_00600	COG0659	secondary active sulfate transmembrane transporter activity
JC774_00615	COG5002	protein histidine kinase activity
JC774_00625	COG0833	amino acid
JC774_00630	COG0765	amino acid transport
JC774_00635	COG0765	amino acid transport
JC774_00640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC774_00645	COG1126	abc transporter atp-binding protein
JC774_00650	COG1115	amino acid carrier protein
JC774_00655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC774_00660	COG0531	amino acid
JC774_00665	COG0714	Associated with various cellular activities
JC774_00670	COG4548	von Willebrand factor, type A
JC774_00675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JC774_00680	COG0156	8-amino-7-oxononanoate synthase activity
JC774_00685	COG3104	oligopeptide transport
JC774_00700	COG1620	l-lactate permease
JC774_00705	COG1027	Aspartate ammonia-lyase
JC774_00710	COG1253	flavin adenine dinucleotide binding
JC774_00715	COG1316	TRANSCRIPTIONal
JC774_00720	COG2720	vancomycin resistance protein
JC774_00740	COG2217	Heavy metal translocating P-type atpase
JC774_00755	COG3227	Zinc metalloprotease (Elastase)
JC774_00770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JC774_00775	COG2217	Heavy metal translocating P-type atpase
JC774_00780	COG0640	Transcriptional regulator
JC774_00790	COG0531	amino acid
JC774_00800	COG0840	transmembrane signaling receptor activity
JC774_00810	COG2427	Protein of unknown function (DUF1641)
JC774_00815	COG3383	formate dehydrogenase (NAD+) activity
JC774_00820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JC774_00825	COG0745	RESPONSE REGULATOR receiver
JC774_00830	COG5002	protein histidine kinase activity
JC774_00845	COG0281	malic enzyme
JC774_00850	COG3493	citrate carrier protein
JC774_00855	COG4565	transcriptional regulatory protein
JC774_00860	COG3290	protein histidine kinase activity
JC774_00870	COG4990	cell redox homeostasis
JC774_00905	COG2268	Band 7 protein
JC774_00910	COG1585	Membrane protein implicated in regulation of membrane protease activity
JC774_00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JC774_00965	COG1280	lysine exporter protein (LysE YggA)
JC774_00980	COG2718	Belongs to the UPF0229 family
JC774_00985	COG2766	serine protein kinase
JC774_00990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JC774_01010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JC774_01015	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JC774_01020	COG0217	transcriptional regulatory protein
JC774_01045	COG0457	Tetratricopeptide repeat
JC774_01145	COG0735	belongs to the Fur family
JC774_01150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JC774_01170	COG4555	ABC transporter
JC774_01175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JC774_01180	COG0067	glutamate synthase
JC774_01180	COG0070	glutamate synthase
JC774_01180	COG0069	glutamate synthase activity
JC774_01185	COG4129	membrane
JC774_01190	COG1132	(ABC) transporter
JC774_01195	COG3557	Belongs to the UPF0374 family
JC774_01220	COG1194	a g-specific adenine glycosylase
JC774_01225	COG1988	membrane-bound metal-dependent
JC774_01250	COG2137	regulation of response to DNA damage stimulus
JC774_01255	COG0402	S-adenosylhomocysteine deaminase activity
JC774_01270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JC774_01275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JC774_01285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JC774_01285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JC774_01295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JC774_01300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC774_01300	COG1263	PTS System
JC774_01305	COG2066	Belongs to the glutaminase family
JC774_01340	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JC774_01360	COG0535	radical SAM domain protein
JC774_01370	COG0387	Pfam Sodium calcium exchanger
JC774_01385	COG0586	Pfam SNARE associated Golgi protein
JC774_01395	COG0681	Belongs to the peptidase S26 family
JC774_01405	COG0697	spore germination
JC774_01410	COG2217	Heavy metal translocating P-type atpase
JC774_01415	COG1295	ribonuclease BN
JC774_01425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JC774_01430	COG4840	Belongs to the UPF0435 family
JC774_01440	COG3853	Toxic anion resistance protein (TelA)
JC774_01450	COG0861	Integral membrane protein TerC family
JC774_01455	COG2310	stress, protein
JC774_01460	COG2310	stress, protein
JC774_01465	COG2310	stress, protein
JC774_01490	COG2270	Major facilitator Superfamily
JC774_01510	COG1819	glycosyl
JC774_01535	COG1116	anion transmembrane transporter activity
JC774_01545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC774_01565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JC774_01575	COG0352	thiamine-phosphate diphosphorylase activity
JC774_01580	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JC774_01585	COG4607	ABC-type enterochelin transport system periplasmic component
JC774_01590	COG4604	ABC transporter, ATP-binding protein
JC774_01595	COG4605	iron ion homeostasis
JC774_01600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC774_01620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC774_01620	COG2190	(PTS) system
JC774_01620	COG1263	PTS System
JC774_01625	COG0366	Alpha amylase catalytic
JC774_01635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JC774_01640	COG0549	Belongs to the carbamate kinase family
JC774_01655	COG2235	arginine
JC774_01670	COG0840	transmembrane signaling receptor activity
JC774_01680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC774_01685	COG0765	amino acid transport
JC774_01695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC774_01695	COG0723	plastoquinol--plastocyanin reductase activity
JC774_01700	COG2814	Major facilitator Superfamily
JC774_01735	COG5002	protein histidine kinase activity
JC774_01740	COG0166	Belongs to the GPI family
JC774_01750	COG0492	ferredoxin-NADP+ reductase activity
JC774_01755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JC774_01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC774_01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC774_01780	COG0450	alkyl hydroperoxide reductase
JC774_01795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JC774_01800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JC774_01805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC774_01815	COG2309	aminopeptidase activity
JC774_01820	COG2076	Multidrug Resistance protein
JC774_01825	COG1012	belongs to the aldehyde dehydrogenase family
JC774_01830	COG0531	amino acid
JC774_01840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JC774_01845	COG0546	phosphoglycolate phosphatase activity
JC774_01850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JC774_01855	COG1597	lipid kinase activity
JC774_01860	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JC774_01865	COG0154	amidase activity
JC774_01870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JC774_01875	COG4682	membrane
JC774_01895	COG2011	ABC-type metal ion transport system permease component
JC774_01905	COG1335	isochorismatase
JC774_01910	COG1012	belongs to the aldehyde dehydrogenase family
JC774_01920	COG4851	CamS sex pheromone cAM373 precursor
JC774_01925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JC774_01930	COG0210	DNA helicase
JC774_01935	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JC774_01955	COG0583	DNA-binding transcription factor activity
JC774_01965	COG0151	Belongs to the GarS family
JC774_01970	COG0138	bifunctional purine biosynthesis protein purh
JC774_01975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JC774_01980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JC774_01985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JC774_01990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JC774_01995	COG0047	phosphoribosylformylglycinamidine synthase activity
JC774_02000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JC774_02005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JC774_02010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JC774_02015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JC774_02020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JC774_02040	COG0697	spore germination
JC774_02060	COG0745	RESPONSE REGULATOR receiver
JC774_02065	COG2205	protein histidine kinase activity
JC774_02130	COG5002	protein histidine kinase activity
JC774_02140	COG2252	PERMEase
JC774_02145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JC774_02145	COG0519	Catalyzes the synthesis of GMP from XMP
JC774_02150	COG0459	protein refolding
JC774_02155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JC774_02160	COG1266	CAAX protease self-immunity
JC774_02170	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JC774_02175	COG0488	(ABC) transporter
JC774_02185	COG0456	acetyltransferase
JC774_02190	COG1214	PFAM Peptidase M22, glycoprotease
JC774_02195	COG0802	atpase or kinase
JC774_02245	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC774_02285	COG3091	SprT-like family
JC774_02295	COG2183	response to ionizing radiation
JC774_02300	COG2337	Toxic component of a toxin-antitoxin (TA) module
JC774_02305	COG0864	Transcriptional regulator
JC774_02315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JC774_02320	COG0736	holo-[acyl-carrier-protein] synthase activity
JC774_02325	COG0457	Tetratricopeptide repeat
JC774_02325	COG0705	Rhomboid family
JC774_02335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JC774_02340	COG1181	Belongs to the D-alanine--D-alanine ligase family
JC774_02345	COG2814	Major facilitator Superfamily
JC774_02355	COG0179	Fumarylacetoacetate (FAA) hydrolase
JC774_02360	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JC774_02375	COG0561	phosphatase activity
JC774_02380	COG4608	Belongs to the ABC transporter superfamily
JC774_02385	COG0444	Belongs to the ABC transporter superfamily
JC774_02390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC774_02395	COG0601	transmembrane transport
JC774_02400	COG0747	negative chemotaxis
JC774_02410	COG0842	Transport permease protein
JC774_02415	COG1511	domain protein
JC774_02415	COG0842	Transport permease protein
JC774_02420	COG1131	(ABC) transporter
JC774_02425	COG2197	response regulator
JC774_02430	COG4585	Histidine kinase
JC774_02455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JC774_02460	COG2146	nitrite reductase [NAD(P)H] activity
JC774_02465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC774_02465	COG1587	Uroporphyrinogen-III synthase
JC774_02475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC774_02475	COG1648	precorrin-2 dehydrogenase activity
JC774_02480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC774_02485	COG0204	Acyl-transferase
JC774_02490	COG1910	domain protein
JC774_02495	COG0725	ABC transporter, periplasmic molybdate-binding protein
JC774_02500	COG4149	molybdate abc transporter
JC774_02510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JC774_02515	COG0656	L-ascorbic acid biosynthetic process
JC774_02525	COG1309	transcriptional regulator
JC774_02535	COG2207	Transcriptional regulator
JC774_02545	COG4166	transmembrane transport
JC774_02550	COG4608	Belongs to the ABC transporter superfamily
JC774_02555	COG0444	Belongs to the ABC transporter superfamily
JC774_02560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC774_02565	COG0601	transmembrane transport
JC774_02575	COG2814	Major facilitator Superfamily
JC774_02605	COG3681	Belongs to the UPF0597 family
JC774_02610	COG3681	Belongs to the UPF0597 family
JC774_02680	COG1266	CAAX protease self-immunity
JC774_02700	COG0457	Tetratricopeptide repeat
JC774_02770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JC774_02780	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JC774_02860	COG0726	polysaccharide deacetylase
JC774_02865	COG2194	sulfuric ester hydrolase activity
JC774_02875	COG0489	protein tyrosine kinase activity
JC774_02880	COG0860	N-Acetylmuramoyl-L-alanine amidase
JC774_02890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JC774_02895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JC774_02905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JC774_02925	COG0202	RNA polymerase activity
JC774_02930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JC774_02935	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JC774_02940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JC774_02950	COG0024	Methionine aminopeptidase
JC774_02955	COG0563	adenylate kinase activity
JC774_02960	COG0201	protein transport
JC774_02965	COG0200	Binds to the 23S rRNA
JC774_02970	COG1841	ribosomal large subunit assembly
JC774_02975	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JC774_02980	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JC774_02990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JC774_03000	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JC774_03005	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JC774_03010	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JC774_03015	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JC774_03020	COG0255	Belongs to the universal ribosomal protein uL29 family
JC774_03025	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JC774_03030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JC774_03035	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JC774_03040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JC774_03045	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JC774_03050	COG0089	rRNA binding
JC774_03055	COG0088	Forms part of the polypeptide exit tunnel
JC774_03060	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JC774_03070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JC774_03075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JC774_03080	COG0049	tRNA binding
JC774_03085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JC774_03090	COG1358	cellular component organization or biogenesis
JC774_03095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JC774_03105	COG2813	Specifically methylates the guanine in position
JC774_03110	COG0222	ribosome binding
JC774_03115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JC774_03120	COG0081	regulation of translation
JC774_03125	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JC774_03130	COG0250	Participates in transcription elongation, termination and antitermination
JC774_03140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JC774_03150	COG3688	RNA-binding protein containing a PIN domain
JC774_03155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JC774_03165	COG0215	cysteine-tRNA ligase activity
JC774_03170	COG1045	serine acetyltransferase
JC774_03175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JC774_03180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JC774_03185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JC774_03190	COG4956	integral membrane protein (PIN domain superfamily)
JC774_03200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JC774_03205	COG0542	response to heat
JC774_03210	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JC774_03215	COG3880	PFAM UvrB UvrC protein
JC774_03265	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC774_03300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JC774_03305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JC774_03310	COG1396	sequence-specific DNA binding
JC774_03315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JC774_03320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JC774_03325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JC774_03330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JC774_03335	COG0512	Glutamine amidotransferase of anthranilate synthase
JC774_03340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JC774_03345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JC774_03350	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JC774_03355	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JC774_03360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JC774_03365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JC774_03375	COG2208	phosphoserine phosphatase activity
JC774_03390	COG1098	S1 RNA binding domain
JC774_03410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JC774_03415	COG3956	TIGRFAM MazG family protein
JC774_03420	COG2244	polysaccharide biosynthetic process
JC774_03425	COG2002	toxin-antitoxin pair type II binding
JC774_03430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JC774_03440	COG0193	aminoacyl-tRNA hydrolase activity
JC774_03450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JC774_03455	COG2088	sporulation resulting in formation of a cellular spore
JC774_03460	COG0251	oxidation-reduction process
JC774_03465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JC774_03470	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JC774_03480	COG4466	Protein conserved in bacteria
JC774_03490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JC774_03500	COG0084	hydrolase, TatD family'
JC774_03510	COG2002	toxin-antitoxin pair type II binding
JC774_03515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JC774_03525	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JC774_03530	COG4467	Involved in initiation control of chromosome replication
JC774_03535	COG1774	PSP1 C-terminal conserved region
JC774_03540	COG0470	DNA polymerase III
JC774_03545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JC774_03550	COG1982	Orn Lys Arg decarboxylase major
JC774_03595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JC774_03600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JC774_03605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JC774_03615	COG0590	tRNA wobble adenosine to inosine editing
JC774_03620	COG1335	isochorismatase
JC774_03625	COG1428	Deoxynucleoside kinase
JC774_03630	COG1428	Deoxynucleoside kinase
JC774_03645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JC774_03650	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JC774_03655	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JC774_03660	COG1686	Belongs to the peptidase S11 family
JC774_03670	COG0516	GMP reductase activity
JC774_03670	COG0517	IMP dehydrogenase activity
JC774_03705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JC774_03710	COG0187	DNA topoisomerase II activity
JC774_03715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JC774_03720	COG2501	S4 domain
JC774_03725	COG0592	DNA-directed DNA polymerase activity
JC774_03730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JC774_03735	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JC774_03740	COG0594	ribonuclease P activity
JC774_03745	COG0706	membrane insertase activity
JC774_03750	COG1847	R3H domain protein
JC774_03755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JC774_03760	COG0445	tRNA wobble uridine modification
JC774_03765	COG0357	Ribosomal RNA small subunit methyltransferase G
JC774_03770	COG1475	DNA binding
JC774_03775	COG1192	Involved in chromosome partitioning
JC774_03780	COG1475	DNA binding
JC774_03790	COG0668	transmembrane transport
JC774_03795	COG4481	Protein conserved in bacteria
JC774_03800	COG0012	GTP binding
JC774_03805	COG0360	Binds together with S18 to 16S ribosomal RNA
JC774_03815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JC774_03820	COG4241	membrane
JC774_03825	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JC774_03830	COG0359	binds to the 23S rRNA
JC774_03835	COG0305	Participates in initiation and elongation during chromosome replication
JC774_03840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JC774_03865	COG0745	RESPONSE REGULATOR receiver
JC774_03870	COG5002	protein histidine kinase activity
JC774_03880	COG4853	Protein conserved in bacteria
JC774_03885	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JC774_03890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JC774_03900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JC774_03975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC774_03975	COG3711	transcriptional antiterminator
JC774_03980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JC774_03990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JC774_03995	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JC774_04000	COG2814	Major facilitator Superfamily
JC774_04010	COG3279	Response regulator of the LytR AlgR family
JC774_04020	COG1346	cytolysis
JC774_04025	COG0628	permease
JC774_04030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC774_04030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC774_04035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JC774_04040	COG1309	transcriptional regulator
JC774_04045	COG0488	(ABC) transporter
JC774_04050	COG0463	Glycosyl transferase, family 2
JC774_04065	COG0463	Glycosyl transferase, family 2
JC774_04080	COG1216	Glycosyl transferase, family 2
JC774_04085	COG1607	acyl-coa hydrolase
JC774_04100	COG0840	transmembrane signaling receptor activity
JC774_04115	COG0438	transferase activity, transferring glycosyl groups
JC774_04120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JC774_04125	COG0477	Major facilitator Superfamily
JC774_04130	COG3279	Response regulator of the LytR AlgR family
JC774_04135	COG1966	Carbon starvation protein
JC774_04145	COG0351	phosphomethylpyrimidine kinase
JC774_04155	COG2873	o-acetylhomoserine
JC774_04160	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JC774_04165	COG0460	homoserine dehydrogenase
JC774_04170	COG2755	lipolytic protein G-D-S-L family
JC774_04175	COG1131	(ABC) transporter
JC774_04180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JC774_04185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JC774_04190	COG2814	Major facilitator Superfamily
JC774_04195	COG0561	phosphatase activity
JC774_04200	COG2233	PERMEase
JC774_04205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JC774_04215	COG2363	Small membrane protein
JC774_04225	COG3773	Cell wall hydrolase
JC774_04235	COG3253	May function as heme-dependent peroxidase
JC774_04240	COG0280	phosphate acetyltransferase
JC774_04255	COG4844	belongs to the
JC774_04260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC774_04265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC774_04270	COG1120	ATPase activity
JC774_04275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JC774_04280	COG1078	dGTPase activity
JC774_04290	COG1994	Peptidase M50
JC774_04300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC774_04305	COG0584	glycerophosphoryl diester phosphodiesterase
JC774_04310	COG0789	Transcriptional regulator
JC774_04315	COG2814	Major facilitator Superfamily
JC774_04320	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JC774_04325	COG0010	Belongs to the arginase family
JC774_04340	COG1619	proteins homologs of microcin C7 resistance protein MccF
JC774_04345	COG4506	Protein conserved in bacteria
JC774_04360	COG2234	aminopeptidase activity
JC774_04365	COG0024	Methionine aminopeptidase
JC774_04370	COG1131	(ABC) transporter
JC774_04375	COG0842	Transport permease protein
JC774_04380	COG4585	Histidine kinase
JC774_04385	COG2197	response regulator
JC774_04400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JC774_04405	COG2181	nitrate reductase activity
JC774_04405	COG0247	lactate metabolic process
JC774_04410	COG0183	Belongs to the thiolase family
JC774_04415	COG1250	3-hydroxyacyl-CoA dehydrogenase
JC774_04420	COG1960	acyl-CoA dehydrogenase activity
JC774_04425	COG1960	acyl-CoA dehydrogenase activity
JC774_04440	COG0504	CTP synthase activity
JC774_04445	COG4821	SIS domain
JC774_04465	COG1494	fructose-1,6-bisphosphatase
JC774_04470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JC774_04480	COG1435	thymidine kinase activity
JC774_04485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JC774_04490	COG2890	protein-(glutamine-N5) methyltransferase activity
JC774_04505	COG0009	L-threonylcarbamoyladenylate synthase
JC774_04520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JC774_04525	COG2259	Doxx family
JC774_04545	COG0698	ribose 5-phosphate isomerase
JC774_04555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JC774_04560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JC774_04585	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JC774_04590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JC774_04595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JC774_04600	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JC774_04605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JC774_04610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JC774_04615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JC774_04630	COG5001	Diguanylate cyclase
JC774_04630	COG3300	MHYT domain
JC774_04640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC774_04645	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC774_04650	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC774_04655	COG0649	NAD binding
JC774_04660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JC774_04670	COG0839	Belongs to the complex I subunit 6 family
JC774_04675	COG0713	ATP synthesis coupled electron transport
JC774_04680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JC774_04685	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JC774_04690	COG1007	ATP synthesis coupled electron transport
JC774_04695	COG4836	Membrane
JC774_04710	COG2385	sporulation resulting in formation of a cellular spore
JC774_04715	COG3279	Response regulator of the LytR AlgR family
JC774_04730	COG0739	heme binding
JC774_04740	COG1609	Transcriptional regulator
JC774_04750	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JC774_04760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JC774_04765	COG1682	transport, permease protein
JC774_04780	COG1215	transferase activity, transferring glycosyl groups
JC774_04780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JC774_04785	COG0438	transferase activity, transferring glycosyl groups
JC774_04795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JC774_04805	COG1316	TRANSCRIPTIONal
JC774_04820	COG5002	protein histidine kinase activity
JC774_04855	COG1136	(ABC) transporter
JC774_04860	COG0577	efflux transmembrane transporter activity
JC774_04900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JC774_04905	COG4715	Zinc finger, swim domain protein
JC774_04920	COG3584	3D domain protein
JC774_04920	COG1388	LysM domain
JC774_04925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JC774_04930	COG1215	transferase activity, transferring glycosyl groups
JC774_04940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC774_04945	COG0791	NLP P60 protein
JC774_04945	COG1388	LysM domain
JC774_04955	COG1368	sulfuric ester hydrolase activity
JC774_04965	COG2389	metal-binding protein
JC774_04970	COG1620	l-lactate permease
JC774_04975	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JC774_04980	COG1294	oxidase, subunit
JC774_04985	COG1271	oxidase subunit
JC774_04995	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JC774_05000	COG1301	dicarboxylic acid transport
JC774_05005	COG1447	Phosphotransferase system cellobiose-specific component IIA
JC774_05020	COG1447	Phosphotransferase system cellobiose-specific component IIA
JC774_05025	COG1486	melibiose metabolic process
JC774_05040	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JC774_05040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JC774_05050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JC774_05055	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JC774_05065	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JC774_05095	COG0457	Tetratricopeptide repeat
JC774_05115	COG1316	TRANSCRIPTIONal
JC774_05120	COG1739	Uncharacterized protein family UPF0029
JC774_05125	COG1307	EDD domain protein, DegV family
JC774_05130	COG1733	regulation of RNA biosynthetic process
JC774_05135	COG0791	NLP P60 protein
JC774_05135	COG1388	LysM domain
JC774_05145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JC774_05150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JC774_05315	COG1598	PFAM Uncharacterised protein family UPF0150
JC774_05425	COG4824	toxin secretion phage lysis holin
JC774_05475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JC774_05495	COG1040	competence protein
JC774_05500	COG1278	Cold shock
JC774_05525	COG2884	Cell division ATP-binding protein ftsE
JC774_05530	COG2177	Part of the ABC transporter FtsEX involved in
JC774_05535	COG0793	Belongs to the peptidase S41A family
JC774_05535	COG3409	Peptidoglycan-binding domain 1 protein
JC774_05540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JC774_05555	COG0583	DNA-binding transcription factor activity
JC774_05575	COG0789	Transcriptional regulator
JC774_05590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JC774_05600	COG1950	PFAM Membrane protein of
JC774_05605	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JC774_05610	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JC774_05620	COG0110	maltose O-acetyltransferase activity
JC774_05625	COG0457	Tetratricopeptide repeat
JC774_05630	COG0492	ferredoxin-NADP+ reductase activity
JC774_05640	COG1051	belongs to the nudix hydrolase family
JC774_05645	COG1660	Displays ATPase and GTPase activities
JC774_05650	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JC774_05655	COG1481	regulation of sporulation
JC774_05660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC774_05670	COG2323	membrane
JC774_05685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JC774_05725	COG0457	Tetratricopeptide repeat
JC774_05735	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JC774_05750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JC774_05755	COG0126	phosphoglycerate kinase activity
JC774_05760	COG0149	triose-phosphate isomerase activity
JC774_05765	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JC774_05770	COG0148	phosphopyruvate hydratase activity
JC774_05780	COG1346	cytolysis
JC774_05785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JC774_05790	COG1647	Serine aminopeptidase, S33
JC774_05795	COG0557	exoribonuclease II activity
JC774_05800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JC774_05815	COG0697	spore germination
JC774_05835	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JC774_05845	COG4977	sequence-specific DNA binding
JC774_05845	COG1917	Cupin 2, conserved barrel domain protein
JC774_05850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC774_05865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JC774_05880	COG1252	NADH dehydrogenase
JC774_05895	COG2910	NAD(P)H-binding
JC774_05900	COG1115	amino acid carrier protein
JC774_05905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC774_05910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC774_05930	COG1121	(ABC) transporter
JC774_05935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JC774_05940	COG0803	Belongs to the bacterial solute-binding protein 9 family
JC774_05965	COG1611	Belongs to the LOG family
JC774_05970	COG0783	Belongs to the Dps family
JC774_05985	COG1741	Belongs to the pirin family
JC774_05990	COG3227	Zinc metalloprotease (Elastase)
JC774_05995	COG2151	metal-sulfur cluster biosynthetic enzyme
JC774_06000	COG0840	transmembrane signaling receptor activity
JC774_06005	COG0840	transmembrane signaling receptor activity
JC774_06010	COG5002	protein histidine kinase activity
JC774_06015	COG0745	RESPONSE REGULATOR receiver
JC774_06020	COG1376	ErfK ybiS ycfS ynhG family protein
JC774_06030	COG0586	Pfam SNARE associated Golgi protein
JC774_06040	COG1131	(ABC) transporter
JC774_06055	COG0745	RESPONSE REGULATOR receiver
JC774_06060	COG5002	protein histidine kinase activity
JC774_06070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC774_06080	COG0706	membrane insertase activity
JC774_06085	COG0531	amino acid
JC774_06105	COG0840	transmembrane signaling receptor activity
JC774_06110	COG0011	TIGRFAM Protein of
JC774_06130	COG1686	Belongs to the peptidase S11 family
JC774_06140	COG1024	Enoyl-CoA hydratase
JC774_06140	COG1250	3-hydroxyacyl-CoA dehydrogenase
JC774_06145	COG0183	Belongs to the thiolase family
JC774_06150	COG1960	acyl-CoA dehydrogenase activity
JC774_06195	COG1393	Belongs to the ArsC family
JC774_06200	COG0509	glycine decarboxylation via glycine cleavage system
JC774_06205	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JC774_06210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC774_06225	COG2011	ABC-type metal ion transport system permease component
JC774_06230	COG1464	Belongs to the NlpA lipoprotein family
JC774_06235	COG0396	ATPase activity
JC774_06240	COG0719	Fe-S assembly protein
JC774_06245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JC774_06250	COG0822	iron-sulfur transferase activity
JC774_06255	COG0719	Fe-S assembly protein
JC774_06270	COG0737	Belongs to the 5'-nucleotidase family
JC774_06275	COG3377	Domain of unknown function (DUF1805)
JC774_06285	COG0739	heme binding
JC774_06290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JC774_06305	COG4377	Putative membrane peptidase family (DUF2324)
JC774_06310	COG0789	Transcriptional regulator
JC774_06320	COG4470	Protein conserved in bacteria
JC774_06330	COG1494	fructose-1,6-bisphosphatase
JC774_06335	COG2445	Protein of unknown function DUF86
JC774_06345	COG0647	UMP catabolic process
JC774_06350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JC774_06355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC774_06360	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JC774_06365	COG4837	Protein of unknown function (DUF1462)
JC774_06380	COG3655	Transcriptional regulator
JC774_06390	COG2824	Alkylphosphonate utilization operon protein PhnA
JC774_06395	COG1252	NADH dehydrogenase
JC774_06405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JC774_06410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JC774_06415	COG0316	Belongs to the HesB IscA family
JC774_06425	COG1683	Conserved Protein
JC774_06440	COG0492	ferredoxin-NADP+ reductase activity
JC774_06445	COG1252	NADH dehydrogenase
JC774_06465	COG3584	3D domain protein
JC774_06475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JC774_06485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JC774_06490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JC774_06495	COG1268	BioY protein
JC774_06505	COG2050	protein possibly involved in aromatic compounds catabolism
JC774_06525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JC774_06530	COG5018	Exonuclease
JC774_06550	COG2032	superoxide dismutase activity
JC774_06555	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JC774_06565	COG2267	carboxylic ester hydrolase activity
JC774_06570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JC774_06575	COG1522	sequence-specific DNA binding
JC774_06580	COG0436	Aminotransferase
JC774_06585	COG1098	S1 RNA binding domain
JC774_06590	COG2155	Conserved Protein
JC774_06595	COG0166	Belongs to the GPI family
JC774_06605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JC774_06610	COG1285	pathogenesis
JC774_06645	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC774_06745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JC774_06750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JC774_06755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JC774_06760	COG0297	glycogen (starch) synthase activity
JC774_06765	COG0058	SHG alpha-glucan phosphorylase activity
JC774_06785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JC774_06790	COG1575	Belongs to the MenA family. Type 1 subfamily
JC774_06795	COG1169	isochorismate synthase
JC774_06800	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JC774_06805	COG0596	Alpha beta hydrolase
JC774_06810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JC774_06815	COG0318	PFAM AMP-dependent synthetase and ligase
JC774_06820	COG4948	Mandelate Racemase Muconate Lactonizing
JC774_06835	COG0577	efflux transmembrane transporter activity
JC774_06840	COG1136	(ABC) transporter
JC774_06845	COG0577	efflux transmembrane transporter activity
JC774_06850	COG2205	protein histidine kinase activity
JC774_06855	COG0745	RESPONSE REGULATOR receiver
JC774_06865	COG1136	(ABC) transporter
JC774_06870	COG1597	lipid kinase activity
JC774_06875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JC774_06915	COG1842	Phage shock protein A
JC774_06945	COG1294	oxidase, subunit
JC774_06950	COG1271	oxidase subunit
JC774_06955	COG0288	reversible hydration of carbon dioxide
JC774_06960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JC774_06965	COG1854	S-ribosylhomocysteine lyase activity
JC774_06975	COG0494	nUDIX hydrolase
JC774_06990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC774_06995	COG1116	anion transmembrane transporter activity
JC774_07000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JC774_07015	COG1368	sulfuric ester hydrolase activity
JC774_07025	COG5632	N-Acetylmuramoyl-L-alanine amidase
JC774_07025	COG3409	Peptidoglycan-binding domain 1 protein
JC774_07030	COG1414	Transcriptional regulator
JC774_07035	COG0246	Mannitol dehydrogenase
JC774_07040	COG1312	Catalyzes the dehydration of D-mannonate
JC774_07045	COG2610	gluconate transmembrane transporter activity
JC774_07050	COG0800	Aldolase
JC774_07100	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JC774_07105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JC774_07130	COG0746	molybdenum cofactor guanylyltransferase activity
JC774_07135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JC774_07140	COG2267	carboxylic ester hydrolase activity
JC774_07150	COG2378	regulation of single-species biofilm formation
JC774_07160	COG1794	racemase activity, acting on amino acids and derivatives
JC774_07170	COG1121	(ABC) transporter
JC774_07175	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JC774_07180	COG1242	4 iron, 4 sulfur cluster binding
JC774_07195	COG0346	lactoylglutathione lyase activity
JC774_07200	COG1136	(ABC) transporter
JC774_07210	COG2814	Major facilitator Superfamily
JC774_07215	COG0495	leucyl-tRNA aminoacylation
JC774_07250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JC774_07260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JC774_07275	COG2181	nitrate reductase activity
JC774_07280	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JC774_07285	COG1140	nitrate reductase beta subunit
JC774_07290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JC774_07295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JC774_07300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JC774_07305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC774_07310	COG0315	cyclic pyranopterin monophosphate synthase activity
JC774_07315	COG0303	'Molybdopterin
JC774_07320	COG1763	Mo-molybdopterin cofactor biosynthetic process
JC774_07325	COG0314	molybdopterin synthase activity
JC774_07335	COG2223	nitrite transmembrane transporter activity
JC774_07345	COG1329	Transcriptional regulator
JC774_07400	COG0463	Glycosyl transferase, family 2
JC774_07420	COG3832	glyoxalase III activity
JC774_07430	COG2814	Major facilitator Superfamily
JC774_07435	COG2081	HI0933 family
JC774_07440	COG2244	polysaccharide biosynthetic process
JC774_07445	COG1187	pseudouridine synthase activity
JC774_07450	COG1349	DNA-binding transcription factor activity
JC774_07455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JC774_07465	COG1523	belongs to the glycosyl hydrolase 13 family
JC774_07470	COG0510	thiamine kinase activity
JC774_07480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JC774_07485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC774_07495	COG1363	Peptidase, m42
JC774_07510	COG0675	Transposase, IS605 OrfB family
JC774_07515	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JC774_07520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC774_07525	COG4848	Belongs to the UPF0354 family
JC774_07530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JC774_07540	COG1674	ftsk spoiiie
JC774_07550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JC774_07555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC774_07565	COG2309	aminopeptidase activity
JC774_07575	COG3118	belongs to the thioredoxin family
JC774_07580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JC774_07580	COG1605	Chorismate mutase
JC774_07585	COG1609	Transcriptional regulator
JC774_07595	COG1970	mechanosensitive ion channel activity
JC774_07600	COG0123	including yeast histone deacetylase and acetoin utilization protein
JC774_07605	COG0517	IMP dehydrogenase activity
JC774_07610	COG0454	-acetyltransferase
JC774_07615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JC774_07625	COG1595	DNA-templated transcription, initiation
JC774_07660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JC774_07665	COG0626	cystathionine gamma-synthase activity
JC774_07670	COG1956	GAF domain-containing protein
JC774_07675	COG1309	transcriptional regulator
JC774_07680	COG0697	spore germination
JC774_07685	COG0583	DNA-binding transcription factor activity
JC774_07690	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JC774_07695	COG1104	cysteine desulfurase activity
JC774_07700	COG0301	tRNA thio-modification
JC774_07710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JC774_07715	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JC774_07730	COG3874	Sporulation protein YtfJ
JC774_07735	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JC774_07740	COG0827	DNA restriction-modification system
JC774_07745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JC774_07755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC774_07765	COG0137	argininosuccinate synthase activity
JC774_07770	COG0165	Argininosuccinate lyase
JC774_07790	COG0589	response to stress
JC774_07795	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_07820	COG0006	proline dipeptidase activity
JC774_07825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JC774_07830	COG4109	DRTGG domain
JC774_07840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JC774_07855	COG0587	DNA-directed DNA polymerase activity
JC774_07860	COG0281	malic enzyme
JC774_07865	COG1725	Transcriptional regulator
JC774_07870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JC774_07875	COG0825	malonyl-CoA metabolic process
JC774_07880	COG0205	6-phosphofructokinase activity
JC774_07890	COG3030	protein affecting phage T7 exclusion by the F plasmid
JC774_07895	COG0628	permease
JC774_07900	COG2707	UPF0756 membrane protein
JC774_07905	COG0372	Belongs to the citrate synthase family
JC774_07910	COG0538	isocitrate dehydrogenase activity
JC774_07915	COG0039	L-malate dehydrogenase activity
JC774_07930	COG0745	RESPONSE REGULATOR receiver
JC774_07935	COG5002	protein histidine kinase activity
JC774_07940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC774_07940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC774_07950	COG1971	Probably functions as a manganese efflux pump
JC774_07960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JC774_07965	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JC774_07970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JC774_07975	COG3611	Membrane attachment protein
JC774_07980	COG1484	DNA-dependent DNA replication
JC774_07990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JC774_08000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JC774_08005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JC774_08015	COG1363	Peptidase, m42
JC774_08020	COG1309	transcriptional regulator
JC774_08025	COG1566	PFAM secretion protein HlyD family protein
JC774_08030	COG2814	Major facilitator Superfamily
JC774_08040	COG1418	mRNA catabolic process
JC774_08050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JC774_08055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JC774_08065	COG0017	Asparaginyl-tRNA synthetase
JC774_08075	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JC774_08080	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JC774_08085	COG1286	toxin biosynthetic process
JC774_08090	COG1796	DNA polymerase
JC774_08090	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JC774_08095	COG1193	negative regulation of DNA recombination
JC774_08100	COG1187	pseudouridine synthase activity
JC774_08105	COG1114	Component of the transport system for branched-chain amino acids
JC774_08110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JC774_08115	COG4895	conserved protein (DUF2196)
JC774_08125	COG0745	RESPONSE REGULATOR receiver
JC774_08130	COG2205	protein histidine kinase activity
JC774_08135	COG1131	(ABC) transporter
JC774_08155	COG2318	DinB family
JC774_08165	COG0318	PFAM AMP-dependent synthetase and ligase
JC774_08170	COG1309	transcriptional regulator
JC774_08175	COG1024	Enoyl-CoA hydratase
JC774_08180	COG2086	electron transfer activity
JC774_08185	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JC774_08190	COG3118	belongs to the thioredoxin family
JC774_08205	COG1719	4-vinyl reductase, 4VR
JC774_08210	COG2009	succinate dehydrogenase
JC774_08215	COG1053	succinate dehydrogenase
JC774_08220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JC774_08230	COG1876	peptidase activity
JC774_08235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JC774_08240	COG1360	Flagellar Motor Protein
JC774_08245	COG4152	abc transporter atp-binding protein
JC774_08250	COG1668	transmembrane transport
JC774_08255	COG1959	2 iron, 2 sulfur cluster binding
JC774_08265	COG2197	response regulator
JC774_08275	COG5401	PFAM Sporulation and spore germination
JC774_08280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JC774_08290	COG0622	Phosphoesterase
JC774_08310	COG1309	transcriptional regulator
JC774_08320	COG1033	growth of symbiont in host cell
JC774_08320	COG2409	Drug exporters of the RND superfamily
JC774_08335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JC774_08335	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_08335	COG4221	oxidoreductase activity
JC774_08335	COG3321	synthase
JC774_08360	COG0544	peptidyl-prolyl cis-trans isomerase activity
JC774_08365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JC774_08370	COG0470	DNA polymerase III
JC774_08370	COG1067	ATP-dependent peptidase activity
JC774_08380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JC774_08385	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JC774_08390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JC774_08395	COG0181	hydroxymethylbilane synthase activity
JC774_08400	COG1587	Uroporphyrinogen-III synthase
JC774_08405	COG0113	porphobilinogen synthase activity
JC774_08410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JC774_08415	COG1388	LysM domain
JC774_08415	COG1388	LysM domain
JC774_08435	COG0285	dihydrofolate synthase activity
JC774_08445	COG0424	maF-like protein
JC774_08465	COG1077	Cell shape determining protein MreB Mrl
JC774_08470	COG1792	Involved in formation and maintenance of cell shape
JC774_08480	COG0850	regulation of cytokinetic process
JC774_08485	COG2894	cell division
JC774_08490	COG0739	heme binding
JC774_08495	COG1994	Peptidase M50
JC774_08500	COG1530	ribonuclease E activity
JC774_08505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JC774_08510	COG2868	ribosomal protein
JC774_08515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JC774_08520	COG3290	protein histidine kinase activity
JC774_08530	COG0745	RESPONSE REGULATOR receiver
JC774_08535	COG5002	protein histidine kinase activity
JC774_08540	COG1136	(ABC) transporter
JC774_08545	COG0577	efflux transmembrane transporter activity
JC774_08550	COG0577	efflux transmembrane transporter activity
JC774_08555	COG0077	Prephenate dehydratase
JC774_08560	COG2258	MOSC domain
JC774_08565	COG1827	regulation of RNA biosynthetic process
JC774_08570	COG1104	cysteine desulfurase activity
JC774_08575	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JC774_08580	COG0157	Belongs to the NadC ModD family
JC774_08585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JC774_08605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JC774_08610	COG0632	four-way junction helicase activity
JC774_08615	COG2255	four-way junction helicase activity
JC774_08625	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JC774_08630	COG0343	queuine tRNA-ribosyltransferase activity
JC774_08635	COG1862	Preprotein translocase
JC774_08655	COG2244	polysaccharide biosynthetic process
JC774_08665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JC774_08665	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JC774_08670	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JC774_08675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JC774_08675	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JC774_08680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JC774_08685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JC774_08690	COG1490	D-aminoacyl-tRNA deacylase activity
JC774_08710	COG0124	histidyl-tRNA synthetase
JC774_08715	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JC774_08720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JC774_08730	COG2207	Transcriptional regulator
JC774_08750	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JC774_08755	COG1959	2 iron, 2 sulfur cluster binding
JC774_08760	COG1104	cysteine desulfurase activity
JC774_08765	COG0482	sulfurtransferase activity
JC774_08775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JC774_08795	COG0628	permease
JC774_08800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JC774_08805	COG4472	Bacterial protein of unknown function (DUF965)
JC774_08810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JC774_08820	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JC774_08825	COG4122	O-methyltransferase activity
JC774_08830	COG0826	peptidase U32
JC774_08835	COG0826	peptidase U32
JC774_08840	COG0572	uridine kinase
JC774_08845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JC774_08855	COG0768	penicillin binding
JC774_08875	COG2226	methyltransferase
JC774_08880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JC774_08885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JC774_08890	COG0626	cystathionine gamma-synthase activity
JC774_08900	COG1609	Transcriptional regulator
JC774_08915	COG2259	Doxx family
JC774_08920	COG2514	catechol 2,3-dioxygenase activity
JC774_08925	COG2154	pterin-4-alpha-carbinolamine dehydratase
JC774_08930	COG3186	Phenylalanine-4-hydroxylase
JC774_08955	COG2267	carboxylic ester hydrolase activity
JC774_08960	COG0456	acetyltransferase
JC774_08965	COG1785	Belongs to the alkaline phosphatase family
JC774_08970	COG2357	RelA SpoT domain protein
JC774_08975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JC774_08990	COG0688	phosphatidylethanolamine metabolic process
JC774_09000	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JC774_09005	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JC774_09010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JC774_09015	COG1534	Rna-binding protein
JC774_09020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JC774_09025	COG1713	HD superfamily hydrolase involved in NAD metabolism
JC774_09030	COG0799	negative regulation of ribosome biogenesis
JC774_09035	COG2226	methyltransferase
JC774_09040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JC774_09045	COG1596	polysaccharide export
JC774_09045	COG1555	photosystem II stabilization
JC774_09050	COG2131	deaminase
JC774_09055	COG2333	competence protein COMEC
JC774_09055	COG0658	competence protein
JC774_09065	COG1466	dna polymerase III delta subunit
JC774_09070	COG0268	Binds directly to 16S ribosomal RNA
JC774_09075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JC774_09085	COG0481	GTPase activity
JC774_09090	COG0693	protein deglycase activity
JC774_09095	COG1733	regulation of RNA biosynthetic process
JC774_09100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JC774_09105	COG1420	regulation of RNA biosynthetic process
JC774_09110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JC774_09115	COG0443	Heat shock 70 kDa protein
JC774_09120	COG0484	heat shock protein binding
JC774_09125	COG2264	protein methyltransferase activity
JC774_09130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JC774_09135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JC774_09140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JC774_09145	COG1610	YqeY-like protein
JC774_09160	COG1702	phosphate starvation-inducible protein PhoH
JC774_09165	COG1480	7TM receptor with intracellular HD hydrolase
JC774_09170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JC774_09175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JC774_09185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JC774_09195	COG1381	Involved in DNA repair and RecF pathway recombination
JC774_09200	COG0517	IMP dehydrogenase activity
JC774_09205	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JC774_09210	COG1671	Belongs to the UPF0178 family
JC774_09215	COG0358	DNA primase activity
JC774_09220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JC774_09230	COG2384	SAM-dependent methyltransferase
JC774_09235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JC774_09240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JC774_09255	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JC774_09265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC774_09270	COG1121	(ABC) transporter
JC774_09275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JC774_09280	COG0735	belongs to the Fur family
JC774_09285	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JC774_09305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JC774_09310	COG0477	Major facilitator Superfamily
JC774_09315	COG0768	penicillin binding
JC774_09320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JC774_09325	COG0573	inorganic phosphate transmembrane transporter activity
JC774_09330	COG0581	inorganic phosphate transmembrane transporter activity
JC774_09340	COG0704	Plays a role in the regulation of phosphate uptake
JC774_09345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JC774_09350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JC774_09355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JC774_09360	COG4483	Protein conserved in bacteria
JC774_09365	COG1940	carbohydrate kinase activity
JC774_09375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC774_09390	COG0626	cystathionine gamma-synthase activity
JC774_09395	COG0626	cystathionine gamma-synthase activity
JC774_09400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JC774_09400	COG0646	methionine synthase
JC774_09405	COG1410	methionine synthase
JC774_09405	COG0646	methionine synthase
JC774_09420	COG1078	dGTPase activity
JC774_09460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JC774_09465	COG1459	type II secretion system
JC774_09490	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JC774_09520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JC774_09525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JC774_09530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JC774_09535	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JC774_09550	COG1725	Transcriptional regulator
JC774_09555	COG1131	(ABC) transporter
JC774_09575	COG2076	Multidrug Resistance protein
JC774_09580	COG2076	Multidrug Resistance protein
JC774_09590	COG1609	Transcriptional regulator
JC774_09600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JC774_09615	COG1321	iron dependent repressor
JC774_09625	COG3872	metal-dependent enzyme
JC774_09635	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JC774_09640	COG0006	proline dipeptidase activity
JC774_09645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JC774_09665	COG3854	ATPases associated with a variety of cellular activities
JC774_09710	COG0511	ligase activity, forming carbon-carbon bonds
JC774_09715	COG0439	Biotin carboxylase
JC774_09720	COG1302	Protein conserved in bacteria
JC774_09725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JC774_09730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JC774_09735	COG1570	exodeoxyribonuclease VII activity
JC774_09740	COG1722	exodeoxyribonuclease VII activity
JC774_09750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JC774_09755	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JC774_09765	COG0497	DNA recombination
JC774_09770	COG0750	zinc metalloprotease
JC774_09780	COG0745	RESPONSE REGULATOR receiver
JC774_09805	COG1136	(ABC) transporter
JC774_09820	COG3093	addiction module antidote protein HigA
JC774_09825	COG0584	glycerophosphoryl diester phosphodiesterase
JC774_09840	COG3829	transcription factor binding
JC774_09840	COG3290	protein histidine kinase activity
JC774_09845	COG0280	phosphate acetyltransferase
JC774_09855	COG3426	butyrate kinase activity
JC774_09860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JC774_09865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JC774_09870	COG0022	dehydrogenase e1 component
JC774_09875	COG0508	dehydrogenase complex catalyzes the overall conversion of
JC774_09880	COG0772	Belongs to the SEDS family
JC774_09885	COG2816	NAD+ diphosphatase activity
JC774_09900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC774_09905	COG0765	amino acid transport
JC774_09910	COG1126	abc transporter atp-binding protein
JC774_09915	COG4129	membrane
JC774_09920	COG1376	ErfK ybiS ycfS ynhG family protein
JC774_09935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC774_09940	COG2195	Cleaves the N-terminal amino acid of tripeptides
JC774_09960	COG1234	tRNA 3'-trailer cleavage
JC774_09970	COG1760	l-serine dehydratase
JC774_09975	COG1760	l-serine dehydratase
JC774_09980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JC774_09985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC774_09990	COG0300	oxidoreductase activity
JC774_10000	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JC774_10010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JC774_10040	COG0737	Belongs to the 5'-nucleotidase family
JC774_10045	COG1757	Na H antiporter
JC774_10055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JC774_10065	COG0156	8-amino-7-oxononanoate synthase activity
JC774_10070	COG0596	Alpha beta hydrolase
JC774_10075	COG4106	trans-aconitate 2-methyltransferase activity
JC774_10080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JC774_10095	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JC774_10095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JC774_10100	COG0307	riboflavin synthase, alpha
JC774_10105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JC774_10105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JC774_10120	COG1073	alpha beta
JC774_10125	COG0456	acetyltransferase
JC774_10130	COG1609	Transcriptional regulator
JC774_10135	COG2056	Na+-H+ antiporter family
JC774_10140	COG0596	Alpha beta hydrolase
JC774_10150	COG0737	Belongs to the 5'-nucleotidase family
JC774_10150	COG1525	nuclease
JC774_10150	COG4085	toxin activity
JC774_10160	COG0456	acetyltransferase
JC774_10160	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JC774_10165	COG0656	L-ascorbic acid biosynthetic process
JC774_10170	COG0667	Aldo Keto reductase
JC774_10190	COG1300	Membrane
JC774_10195	COG0735	belongs to the Fur family
JC774_10205	COG4974	Belongs to the 'phage' integrase family
JC774_10230	COG0598	Magnesium transport protein CorA
JC774_10245	COG1846	Transcriptional regulator
JC774_10265	COG1131	(ABC) transporter
JC774_10270	COG1725	Transcriptional regulator
JC774_10275	COG1686	Belongs to the peptidase S11 family
JC774_10285	COG2172	sigma factor antagonist activity
JC774_10295	COG0733	neurotransmitter:sodium symporter activity
JC774_10320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JC774_10335	COG0697	spore germination
JC774_10340	COG0561	phosphatase activity
JC774_10345	COG4086	secreted protein
JC774_10350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JC774_10360	COG1547	Domain of unknown function (DUF309)
JC774_10370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JC774_10375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JC774_10390	COG0363	glucosamine-6-phosphate deaminase activity
JC774_10395	COG2188	Transcriptional regulator
JC774_10405	COG3711	transcriptional antiterminator
JC774_10410	COG1263	PTS System
JC774_10410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC774_10410	COG2190	(PTS) system
JC774_10435	COG0778	Nitroreductase
JC774_10440	COG2199	diguanylate cyclase activity
JC774_10450	COG2084	Dehydrogenase
JC774_10465	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JC774_10470	COG0235	Class ii aldolase
JC774_10475	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JC774_10480	COG1850	ribulose-bisphosphate carboxylase activity
JC774_10485	COG0436	Aminotransferase
JC774_10490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JC774_10495	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JC774_10500	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JC774_10510	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_10515	COG1695	Transcriptional regulator
JC774_10540	COG0183	Belongs to the thiolase family
JC774_10570	COG1609	Transcriptional regulator
JC774_10575	COG0436	Aminotransferase
JC774_10585	COG2205	protein histidine kinase activity
JC774_10595	COG3209	COG3209 Rhs family protein
JC774_10605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JC774_10610	COG2814	Major facilitator Superfamily
JC774_10650	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JC774_10660	COG1408	metallophosphoesterase
JC774_10665	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_10670	COG2200	EAL domain
JC774_10685	COG4703	Protein of unknown function (DUF1797)
JC774_10695	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JC774_10705	COG0517	IMP dehydrogenase activity
JC774_10710	COG0583	DNA-binding transcription factor activity
JC774_10715	COG2171	N-acyltransferase activity
JC774_10720	COG1473	amidohydrolase
JC774_10730	COG0569	domain protein
JC774_10735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JC774_10740	COG5503	Protein of unknown function (DUF1447)
JC774_10745	COG0561	phosphatase activity
JC774_10760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JC774_10770	COG0508	dehydrogenase complex catalyzes the overall conversion of
JC774_10805	COG1982	Orn Lys Arg decarboxylase major
JC774_10810	COG4476	Belongs to the UPF0223 family
JC774_10815	COG4493	Belongs to the UPF0637 family
JC774_10825	COG0483	inositol monophosphate 1-phosphatase activity
JC774_10835	COG1217	gtp-binding protein TYPA
JC774_10850	COG4896	Protein conserved in bacteria
JC774_10860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JC774_10865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JC774_10870	COG4838	Belongs to the UPF0358 family
JC774_10875	COG0772	Belongs to the SEDS family
JC774_10880	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JC774_10885	COG1612	heme a metabolic process
JC774_10890	COG0109	protoheme IX farnesyltransferase activity
JC774_10900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JC774_10915	COG3336	cytochrome c oxidase
JC774_10925	COG2340	Cysteine-rich secretory protein family
JC774_10940	COG0406	alpha-ribazole phosphatase activity
JC774_10945	COG3679	Belongs to the UPF0342 family
JC774_10950	COG4471	UPF0298 protein
JC774_10960	COG0742	ribosomal rna small subunit methyltransferase
JC774_10965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JC774_10970	COG3314	Sporulation integral membrane protein YlbJ
JC774_10975	COG1752	Esterase of the alpha-beta hydrolase superfamily
JC774_10980	COG3480	Lon protease (S16) C-terminal proteolytic domain
JC774_10985	COG1323	Belongs to the UPF0348 family
JC774_10990	COG0582	viral genome integration into host DNA
JC774_10995	COG1396	sequence-specific DNA binding
JC774_11010	COG1396	sequence-specific DNA binding
JC774_11050	COG5377	YqaJ viral recombinase family
JC774_11060	COG3723	Recombinational DNA repair protein, rece pathway
JC774_11090	COG2002	toxin-antitoxin pair type II binding
JC774_11175	COG1802	Transcriptional regulator
JC774_11175	COG4626	Terminase
JC774_11285	COG1399	metal-binding, possibly nucleic acid-binding protein
JC774_11290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JC774_11300	COG0454	-acetyltransferase
JC774_11305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JC774_11310	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JC774_11315	COG0275	rRNA processing
JC774_11320	COG4839	cell division protein FtsL
JC774_11325	COG0768	penicillin binding
JC774_11330	COG0768	penicillin binding
JC774_11335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JC774_11340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JC774_11345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JC774_11350	COG0772	Belongs to the SEDS family
JC774_11355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JC774_11365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JC774_11370	COG0849	cell division
JC774_11375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JC774_11385	COG1191	sigma factor activity
JC774_11390	COG1191	sigma factor activity
JC774_11395	COG1873	PFAM PRC-barrel domain
JC774_11405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JC774_11410	COG1799	cell septum assembly
JC774_11415	COG0762	integral membrane protein
JC774_11420	COG2302	S4 RNA-binding domain
JC774_11425	COG3599	regulation of cell shape
JC774_11430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JC774_11440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JC774_11445	COG0564	pseudouridine synthase activity
JC774_11450	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JC774_11460	COG0540	Belongs to the ATCase OTCase family
JC774_11465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JC774_11475	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JC774_11480	COG0543	2 iron, 2 sulfur cluster binding
JC774_11485	COG0167	dihydroorotate dehydrogenase activity
JC774_11490	COG0284	orotidine-5'-phosphate decarboxylase activity
JC774_11495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JC774_11520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JC774_11525	COG1561	YicC-like family, N-terminal region
JC774_11540	COG1758	RNA polymerase activity
JC774_11545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JC774_11550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JC774_11555	COG0242	peptide deformylase activity
JC774_11560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JC774_11565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JC774_11565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JC774_11570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JC774_11575	COG0631	protein serine/threonine phosphatase activity
JC774_11580	COG0515	serine threonine protein kinase
JC774_11580	COG2815	serine threonine protein kinase
JC774_11585	COG1162	GTPase activity
JC774_11590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JC774_11595	COG1564	THIamine pyrophosphokinase
JC774_11605	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JC774_11610	COG1302	Protein conserved in bacteria
JC774_11615	COG1461	Dihydroxyacetone kinase
JC774_11620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JC774_11625	COG2050	protein possibly involved in aromatic compounds catabolism
JC774_11625	COG1349	DNA-binding transcription factor activity
JC774_11630	COG0416	fatty acid biosynthetic process
JC774_11635	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JC774_11640	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_11645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JC774_11650	COG0571	ribonuclease III activity
JC774_11655	COG1196	nuclear chromosome segregation
JC774_11660	COG0552	protein localization to endoplasmic reticulum
JC774_11665	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JC774_11670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JC774_11675	COG0228	four-way junction DNA binding
JC774_11680	COG1837	Belongs to the UPF0109 family
JC774_11685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JC774_11690	COG0336	Belongs to the RNA methyltransferase TrmD family
JC774_11695	COG0335	large ribosomal subunit rRNA binding
JC774_11710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JC774_11715	COG0045	succinate-CoA ligase (ADP-forming) activity
JC774_11720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JC774_11725	COG0758	DNA mediated transformation
JC774_11730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JC774_11735	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JC774_11740	COG4974	Belongs to the 'phage' integrase family
JC774_11745	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JC774_11750	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JC774_11755	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JC774_11760	COG0052	Belongs to the universal ribosomal protein uS2 family
JC774_11765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JC774_11770	COG0528	UMP kinase activity
JC774_11775	COG0233	cytoplasmic translational termination
JC774_11785	COG4589	Belongs to the CDS family
JC774_11795	COG0750	zinc metalloprotease
JC774_11800	COG0442	prolyl-tRNA aminoacylation
JC774_11810	COG0779	Required for maturation of 30S ribosomal subunits
JC774_11815	COG0195	Participates in both transcription termination and antitermination
JC774_11820	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JC774_11825	COG1358	cellular component organization or biogenesis
JC774_11830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JC774_11835	COG1550	Protein conserved in bacteria
JC774_11840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JC774_11845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JC774_11850	COG0196	riboflavin kinase activity
JC774_11860	COG1185	polyribonucleotide nucleotidyltransferase activity
JC774_11865	COG0726	polysaccharide deacetylase
JC774_11870	COG0612	Peptidase, M16
JC774_11875	COG1873	PFAM PRC-barrel domain
JC774_11880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JC774_11885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JC774_11890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JC774_11895	COG0527	aspartate kinase activity
JC774_11915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JC774_11940	COG0740	serine-type endopeptidase activity
JC774_11960	COG1674	ftsk spoiiie
JC774_11965	COG2188	Transcriptional regulator
JC774_11970	COG1744	ABC transporter substrate-binding protein PnrA-like
JC774_11975	COG3845	ABC transporter
JC774_11980	COG4603	Belongs to the binding-protein-dependent transport system permease family
JC774_11985	COG1079	Belongs to the binding-protein-dependent transport system permease family
JC774_11990	COG0612	Peptidase, M16
JC774_11995	COG0612	Peptidase, M16
JC774_12000	COG0300	oxidoreductase activity
JC774_12020	COG1426	Protein conserved in bacteria
JC774_12025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JC774_12030	COG1546	Belongs to the CinA family
JC774_12030	COG1058	Belongs to the CinA family
JC774_12035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JC774_12040	COG1418	mRNA catabolic process
JC774_12045	COG1692	metallophosphoesterase
JC774_12050	COG2359	stage V sporulation protein S
JC774_12060	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JC774_12060	COG0674	pyruvate-flavodoxin oxidoreductase activity
JC774_12065	COG1013	pyruvate-flavodoxin oxidoreductase activity
JC774_12070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JC774_12075	COG4550	Control of competence regulator ComK, YlbF/YmcA
JC774_12085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JC774_12090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JC774_12100	COG1113	amino acid transport
JC774_12110	COG0346	lactoylglutathione lyase activity
JC774_12120	COG2195	Cleaves the N-terminal amino acid of tripeptides
JC774_12125	COG2706	6-phosphogluconolactonase activity
JC774_12130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JC774_12135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC774_12140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JC774_12145	COG1120	ATPase activity
JC774_12150	COG2819	hydrolase of the alpha beta superfamily
JC774_12155	COG1937	Protein conserved in bacteria
JC774_12165	COG2116	formate transmembrane transporter activity
JC774_12185	COG2322	membrane
JC774_12190	COG1349	DNA-binding transcription factor activity
JC774_12195	COG1105	Belongs to the carbohydrate kinase PfkB family
JC774_12200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC774_12200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC774_12200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC774_12205	COG1388	LysM domain
JC774_12205	COG3584	3D domain protein
JC774_12215	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JC774_12220	COG1923	regulation of RNA biosynthetic process
JC774_12235	COG0464	growth
JC774_12245	COG2860	membrane
JC774_12250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JC774_12255	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JC774_12260	COG0789	Transcriptional regulator
JC774_12265	COG0174	glutamine synthetase
JC774_12325	COG0730	response to heat
JC774_12335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC774_12365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JC774_12370	COG1598	PFAM Uncharacterised protein family UPF0150
JC774_12375	COG3328	transposase activity
JC774_12380	COG3328	transposase activity
JC774_12420	COG1695	Transcriptional regulator
JC774_12435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JC774_12440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JC774_12445	COG4224	UPF0291 protein
JC774_12450	COG0737	Belongs to the 5'-nucleotidase family
JC774_12465	COG3639	organic phosphonate transmembrane transporter activity
JC774_12470	COG3639	organic phosphonate transmembrane transporter activity
JC774_12485	COG3763	UPF0154 protein
JC774_12490	COG1132	(ABC) transporter
JC774_12495	COG1132	(ABC) transporter
JC774_12510	COG5632	N-Acetylmuramoyl-L-alanine amidase
JC774_12510	COG3409	Peptidoglycan-binding domain 1 protein
JC774_12520	COG0730	response to heat
JC774_12530	COG0833	amino acid
JC774_12540	COG4187	Peptidase family M20/M25/M40
JC774_12545	COG1346	cytolysis
JC774_12550	COG1380	Effector of murein hydrolase LrgA
JC774_12555	COG0583	DNA-binding transcription factor activity
JC774_12560	COG1473	amidohydrolase
JC774_12570	COG0785	Cytochrome C biogenesis protein
JC774_12575	COG4846	Membrane protein involved in cytochrome C biogenesis
JC774_12595	COG2986	histidine ammonia-lyase
JC774_12600	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JC774_12605	COG1228	amidohydrolase
JC774_12610	COG0010	Belongs to the arginase family
JC774_12615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC774_12620	COG5002	protein histidine kinase activity
JC774_12630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC774_12640	COG3023	N-Acetylmuramoyl-L-alanine amidase
JC774_12665	COG0534	Mate efflux family protein
JC774_12680	COG2826	transposase and inactivated derivatives, IS30 family
JC774_12770	COG0318	PFAM AMP-dependent synthetase and ligase
JC774_12775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JC774_12815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JC774_12825	COG3655	Transcriptional regulator
JC774_12830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC774_12860	COG0824	Thioesterase
JC774_12865	COG4841	protein insertion into membrane
JC774_12870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JC774_12885	COG0745	RESPONSE REGULATOR receiver
JC774_12890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JC774_12895	COG1832	CoA-binding protein
JC774_12900	COG0187	DNA topoisomerase II activity
JC774_12905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JC774_12910	COG0673	inositol 2-dehydrogenase activity
JC774_12915	COG1301	dicarboxylic acid transport
JC774_12920	COG4166	transmembrane transport
JC774_12925	COG4166	transmembrane transport
JC774_12930	COG2226	methyltransferase
JC774_12965	COG2962	Rard protein
JC774_12970	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JC774_12975	COG1657	PFAM Prenyltransferase squalene oxidase
JC774_12985	COG1012	belongs to the aldehyde dehydrogenase family
JC774_12990	COG3924	membrane
JC774_12995	COG4145	pantothenate transmembrane transporter activity
JC774_13010	COG3409	Peptidoglycan-binding domain 1 protein
JC774_13025	COG0165	Argininosuccinate lyase
JC774_13030	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_13040	COG1278	Cold shock
JC774_13065	COG0582	viral genome integration into host DNA
JC774_13105	COG1484	DNA-dependent DNA replication
JC774_13185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC774_13185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC774_13205	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JC774_13255	COG0270	DNA (cytosine-5-)-methyltransferase activity
JC774_13440	COG2720	vancomycin resistance protein
JC774_13445	COG1285	pathogenesis
JC774_13450	COG0277	FAD linked oxidase domain protein
JC774_13455	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JC774_13465	COG3397	chitin binding
JC774_13495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC774_13500	COG0584	glycerophosphoryl diester phosphodiesterase
JC774_13520	COG1164	Oligoendopeptidase f
JC774_13530	COG1193	negative regulation of DNA recombination
JC774_13540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JC774_13545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JC774_13575	COG2072	flavoprotein involved in K transport
JC774_13695	COG0577	efflux transmembrane transporter activity
JC774_13695	COG1136	(ABC) transporter
JC774_13745	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JC774_13800	COG0384	phenazine biosynthesis protein PhzF
JC774_13815	COG3813	Protein conserved in bacteria
JC774_13820	COG0789	Transcriptional regulator
JC774_13825	COG1253	flavin adenine dinucleotide binding
JC774_13835	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JC774_13840	COG0579	oxidoreductase
JC774_13845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC774_13850	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JC774_13890	COG2365	Tyrosine phosphatase family
JC774_13910	COG1131	(ABC) transporter
JC774_13925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JC774_13950	COG1122	ATPase activity
JC774_13980	COG2031	fatty acid transporter
JC774_13990	COG2814	Major facilitator Superfamily
JC774_13995	COG1846	Transcriptional regulator
JC774_14010	COG0477	Major facilitator Superfamily
JC774_14160	COG4851	CamS sex pheromone cAM373 precursor
JC774_14180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JC774_14190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC774_14195	COG0438	transferase activity, transferring glycosyl groups
JC774_14200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JC774_14215	COG0438	transferase activity, transferring glycosyl groups
JC774_14220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JC774_14225	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JC774_14230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JC774_14240	COG0346	lactoylglutathione lyase activity
JC774_14255	COG3314	Sporulation integral membrane protein YlbJ
JC774_14265	COG1960	acyl-CoA dehydrogenase activity
JC774_14280	COG1414	Transcriptional regulator
JC774_14285	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JC774_14290	COG1984	allophanate hydrolase subunit 2
JC774_14295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JC774_14310	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JC774_14330	COG0833	amino acid
JC774_14340	COG0730	response to heat
JC774_14355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JC774_14365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC774_14370	COG0697	spore germination
JC774_14380	COG0477	Major facilitator Superfamily
JC774_14385	COG0456	acetyltransferase
JC774_14400	COG0494	nUDIX hydrolase
JC774_14425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC774_14440	COG2329	Antibiotic biosynthesis monooxygenase
JC774_14475	COG1518	maintenance of DNA repeat elements
JC774_14480	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JC774_14485	COG3547	Transposase (IS116 IS110 IS902 family)
JC774_14495	COG0346	lactoylglutathione lyase activity
JC774_14515	COG1605	Chorismate mutase
JC774_14515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JC774_14520	COG0488	(ABC) transporter
JC774_14525	COG1368	sulfuric ester hydrolase activity
JC774_14530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC774_14570	COG2746	aminoglycoside 3-N-acetyltransferase activity
JC774_14585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JC774_14590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC774_14595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JC774_14605	COG0628	permease
JC774_14630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JC774_14635	COG3973	AAA domain
JC774_14650	COG0436	Aminotransferase
JC774_14670	COG2826	transposase and inactivated derivatives, IS30 family
JC774_14690	COG0675	Transposase, IS605 OrfB family
JC774_14695	COG2261	transglycosylase associated protein
JC774_14755	COG1307	EDD domain protein, DegV family
JC774_14830	COG4948	Mandelate Racemase Muconate Lactonizing
JC774_14840	COG4166	transmembrane transport
JC774_14885	COG3397	chitin binding
JC774_14890	COG1227	inorganic diphosphatase activity
JC774_14895	COG4637	Psort location Cytoplasmic, score
JC774_14920	COG0514	ATP-dependent DNA helicase (RecQ)
JC774_14945	COG2153	protein acetylation
JC774_14975	COG4175	Glycine betaine
JC774_14975	COG0517	IMP dehydrogenase activity
JC774_14980	COG4176	ABC-type proline glycine betaine transport system permease component
JC774_14990	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_15000	COG3844	kynureninase activity
JC774_15005	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JC774_15035	COG2959	enzyme of heme biosynthesis
JC774_15045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JC774_15055	COG0673	inositol 2-dehydrogenase activity
JC774_15060	COG3718	enzyme involved in inositol metabolism
JC774_15065	COG1609	Transcriptional regulator
JC774_15090	COG0673	inositol 2-dehydrogenase activity
JC774_15095	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC774_15100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JC774_15130	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JC774_15175	COG2124	cytochrome p450
JC774_15195	COG0561	phosphatase activity
JC774_15200	COG5002	protein histidine kinase activity
JC774_15205	COG2828	Protein conserved in bacteria
JC774_15215	COG1794	racemase activity, acting on amino acids and derivatives
JC774_15250	COG1279	arginine transmembrane transporter activity
JC774_15255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC774_15270	COG1216	Glycosyl transferase, family 2
JC774_15310	COG2223	nitrite transmembrane transporter activity
JC774_15355	COG4667	esterase of the alpha-beta hydrolase superfamily
JC774_15365	COG2318	DinB family
JC774_15370	COG0322	excinuclease ABC activity
JC774_15375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC774_15400	COG0201	protein transport
JC774_15405	COG0693	protein deglycase activity
JC774_15425	COG2002	toxin-antitoxin pair type II binding
JC774_15450	COG0745	RESPONSE REGULATOR receiver
JC774_15475	COG0789	Transcriptional regulator
JC774_15505	COG5002	protein histidine kinase activity
JC774_15510	COG1686	Belongs to the peptidase S11 family
JC774_15515	COG0640	Transcriptional regulator
JC774_15520	COG1216	Glycosyl transferase, family 2
JC774_15530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JC774_15535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JC774_15540	COG1024	Enoyl-CoA hydratase
JC774_15545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JC774_15550	COG0511	ligase activity, forming carbon-carbon bonds
JC774_15555	COG0439	Biotin carboxylase
JC774_15560	COG1960	acyl-CoA dehydrogenase activity
JC774_15570	COG2195	Cleaves the N-terminal amino acid of tripeptides
JC774_15600	COG0588	phosphoglycerate mutase activity
JC774_15620	COG2971	BadF BadG BcrA BcrD
JC774_15635	COG1649	PFAM Uncharacterised BCR, COG1649
JC774_15665	COG1132	(ABC) transporter
JC774_15670	COG1132	(ABC) transporter
JC774_15680	COG0010	Belongs to the arginase family
JC774_15700	COG0667	Aldo Keto reductase
JC774_15705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JC774_15710	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JC774_15745	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JC774_15765	COG0776	regulation of translation
JC774_15785	COG3251	PFAM MbtH domain protein
JC774_15790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JC774_15795	COG3433	isochorismatase activity
JC774_15795	COG1535	isochorismatase
JC774_15800	COG1021	2,3-dihydroxybenzoate-AMP ligase
JC774_15805	COG1169	isochorismate synthase
JC774_15810	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_15835	COG1942	4-Oxalocrotonate Tautomerase
JC774_15865	COG3104	oligopeptide transport
JC774_15870	COG0419	ATPase involved in DNA repair
JC774_15875	COG0420	3'-5' exonuclease activity
JC774_15895	COG1280	lysine exporter protein (LysE YggA)
JC774_15905	COG1012	belongs to the aldehyde dehydrogenase family
JC774_15910	COG2084	Dehydrogenase
JC774_15915	COG1960	acyl-CoA dehydrogenase activity
JC774_15920	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JC774_15925	COG2079	MmgE PrpD family protein
JC774_15930	COG0372	Belongs to the citrate synthase family
JC774_15940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC774_15940	COG4499	WXG100 protein secretion system (Wss), protein YukC
JC774_15965	COG3403	YqcI/YcgG family
JC774_15970	COG1280	lysine exporter protein (LysE YggA)
JC774_15985	COG4990	cell redox homeostasis
JC774_15990	COG0671	phosphoesterase, PA-phosphatase related
JC774_15995	COG2323	membrane
JC774_16000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JC774_16005	COG1408	metallophosphoesterase
JC774_16010	COG0726	polysaccharide deacetylase
JC774_16020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JC774_16060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JC774_16065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JC774_16070	COG0671	phosphoesterase, PA-phosphatase related
JC774_16075	COG0515	serine threonine protein kinase
JC774_16075	COG1357	PFAM Pentapeptide repeats (8 copies)
JC774_16110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JC774_16120	COG4479	Belongs to the UPF0346 family
JC774_16130	COG1509	lysine 2,3-aminomutase activity
JC774_16135	COG3829	transcription factor binding
JC774_16140	COG0456	acetyltransferase
JC774_16145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JC774_16150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JC774_16155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JC774_16160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JC774_16180	COG5506	Protein of unknown function (DUF1694)
JC774_16185	COG1253	flavin adenine dinucleotide binding
JC774_16195	COG1151	hydroxylamine reductase activity
JC774_16250	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JC774_16260	COG1070	Carbohydrate kinase
JC774_16265	COG1737	Transcriptional regulator
JC774_16275	COG0071	Belongs to the small heat shock protein (HSP20) family
JC774_16295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JC774_16305	COG0367	asparagine synthase
JC774_16310	COG0071	Belongs to the small heat shock protein (HSP20) family
JC774_16315	COG1999	signal sequence binding
JC774_16325	COG1307	EDD domain protein, DegV family
JC774_16335	COG0805	protein transport
JC774_16340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JC774_16345	COG1272	protein, Hemolysin III
JC774_16350	COG0204	Acyl-transferase
JC774_16360	COG0768	penicillin binding
JC774_16370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JC774_16375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JC774_16390	COG4473	ABC transporter
JC774_16395	COG1131	(ABC) transporter
JC774_16405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JC774_16410	COG0456	acetyltransferase
JC774_16420	COG2610	gluconate transmembrane transporter activity
JC774_16425	COG1454	alcohol dehydrogenase
JC774_16440	COG0477	Major facilitator Superfamily
JC774_16445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC774_16455	COG0596	Alpha beta hydrolase
JC774_16460	COG0733	neurotransmitter:sodium symporter activity
JC774_16470	COG0018	arginyl-trna synthetase
JC774_16475	COG2136	Putative SAM-dependent methyltransferase
JC774_16475	COG2521	methyltransferase
JC774_16490	COG1413	lyase activity
JC774_16495	COG0629	single-stranded DNA binding
JC774_16505	COG0488	(ABC) transporter
JC774_16510	COG1418	mRNA catabolic process
JC774_16550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JC774_16555	COG0798	PFAM Bile acid sodium symporter
JC774_16560	COG0640	Transcriptional regulator
JC774_16585	COG0386	Belongs to the glutathione peroxidase family
JC774_16610	COG2226	methyltransferase
JC774_16635	COG3874	Sporulation protein YtfJ
JC774_16675	COG4499	WXG100 protein secretion system (Wss), protein YukC
JC774_16720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JC774_16725	COG1819	glycosyl
JC774_16730	COG1819	glycosyl
JC774_16735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JC774_16785	COG1876	peptidase activity
JC774_16795	COG0860	N-Acetylmuramoyl-L-alanine amidase
JC774_16810	COG1114	Component of the transport system for branched-chain amino acids
JC774_16825	COG1253	flavin adenine dinucleotide binding
JC774_16830	COG2839	Protein conserved in bacteria
JC774_16840	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_16850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JC774_16860	COG1607	acyl-coa hydrolase
JC774_16865	COG3689	TIGRFAM TIGR03943 family protein
JC774_16870	COG0701	Predicted permease
JC774_16880	COG2244	polysaccharide biosynthetic process
JC774_16885	COG0586	Pfam SNARE associated Golgi protein
JC774_16890	COG1051	belongs to the nudix hydrolase family
JC774_16895	COG5337	Spore coat protein CotH
JC774_16905	COG0346	lactoylglutathione lyase activity
JC774_16910	COG4166	transmembrane transport
JC774_16925	COG1902	pentaerythritol trinitrate reductase activity
JC774_16940	COG0477	Major facilitator Superfamily
JC774_16945	COG1733	regulation of RNA biosynthetic process
JC774_16965	COG1492	cobalamin metabolic process
JC774_16985	COG0477	Major facilitator Superfamily
JC774_17010	COG0803	Belongs to the bacterial solute-binding protein 9 family
JC774_17020	COG0523	cobalamin synthesis protein
JC774_17040	COG0783	Belongs to the Dps family
JC774_17045	COG3949	Membrane
JC774_17060	COG0840	transmembrane signaling receptor activity
JC774_17075	COG1404	Belongs to the peptidase S8 family
JC774_17080	COG2409	Drug exporters of the RND superfamily
JC774_17085	COG0577	efflux transmembrane transporter activity
JC774_17090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JC774_17110	COG1752	Esterase of the alpha-beta hydrolase superfamily
JC774_17125	COG1247	-acetyltransferase
JC774_17130	COG1285	pathogenesis
JC774_17145	COG1316	TRANSCRIPTIONal
JC774_17150	COG0083	homoserine kinase activity
JC774_17160	COG0460	homoserine dehydrogenase
JC774_17170	COG0300	oxidoreductase activity
JC774_17175	COG0791	NLP P60 protein
JC774_17175	COG1388	LysM domain
JC774_17190	COG1686	Belongs to the peptidase S11 family
JC774_17215	COG0523	cobalamin synthesis protein
JC774_17225	COG0628	permease
JC774_17230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JC774_17235	COG1012	belongs to the aldehyde dehydrogenase family
JC774_17250	COG1454	alcohol dehydrogenase
JC774_17255	COG1012	belongs to the aldehyde dehydrogenase family
JC774_17260	COG1510	regulation of RNA biosynthetic process
JC774_17270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JC774_17285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JC774_17290	COG2390	Transcriptional regulator
JC774_17300	COG0083	homoserine kinase activity
JC774_17310	COG1054	Belongs to the UPF0176 family
JC774_17315	COG1914	H( )-stimulated, divalent metal cation uptake system
JC774_17325	COG4166	transmembrane transport
JC774_17330	COG0402	S-adenosylhomocysteine deaminase activity
JC774_17350	COG3384	dioxygenase
JC774_17355	COG2814	Major facilitator Superfamily
JC774_17360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC774_17365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JC774_17370	COG0129	dihydroxy-acid dehydratase activity
JC774_17385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JC774_17390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JC774_17400	COG5566	PFAM Mor transcription activator
JC774_17405	COG0733	neurotransmitter:sodium symporter activity
JC774_17410	COG2244	polysaccharide biosynthetic process
JC774_17415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JC774_17420	COG2223	nitrite transmembrane transporter activity
JC774_17425	COG4166	transmembrane transport
JC774_17430	COG0488	(ABC) transporter
JC774_17435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JC774_17450	COG3290	protein histidine kinase activity
JC774_17465	COG4512	PFAM Accessory gene regulator B
JC774_17505	COG1131	(ABC) transporter
JC774_17575	COG0109	protoheme IX farnesyltransferase activity
JC774_17585	COG2502	aspartate--ammonia ligase
JC774_17595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JC774_17600	COG1280	lysine exporter protein (LysE YggA)
JC774_17605	COG2733	membrane
JC774_17610	COG3340	Belongs to the peptidase S51 family
JC774_17615	COG0534	Mate efflux family protein
JC774_17640	COG1757	Na H antiporter
JC774_17650	COG0697	spore germination
JC774_17655	COG1802	Transcriptional regulator
JC774_17675	COG0367	asparagine synthase
JC774_17710	COG1136	(ABC) transporter
JC774_17715	COG1309	transcriptional regulator
JC774_17745	COG2814	Major facilitator Superfamily
JC774_17760	COG1309	transcriptional regulator
JC774_17790	COG1136	(ABC) transporter
JC774_17790	COG0577	efflux transmembrane transporter activity
JC774_17795	COG4786	Flagellar basal body rod
JC774_17800	COG1419	protein localization to endoplasmic reticulum
JC774_17805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JC774_17810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JC774_17820	COG1987	bacterial-type flagellum assembly
JC774_17825	COG1338	Plays a role in the flagellum-specific transport system
JC774_17835	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC774_17840	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC774_17850	COG0741	lytic transglycosylase activity
JC774_17855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JC774_17870	COG0457	Tetratricopeptide repeat
JC774_17870	COG0463	Glycosyl transferase, family 2
JC774_17875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JC774_17885	COG0784	Response regulator, receiver
JC774_17885	COG0835	chemotaxis
JC774_17920	COG1157	protein secretion by the type III secretion system
JC774_17930	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC774_17945	COG1558	bacterial-type flagellum-dependent cell motility
JC774_17950	COG1815	bacterial-type flagellum-dependent cell motility
JC774_17970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JC774_17975	COG1256	bacterial-type flagellum assembly
JC774_17985	COG1728	Protein conserved in bacteria
JC774_17995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JC774_18010	COG1776	CheC inhibitor of MCP methylation
JC774_18010	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JC774_18015	COG0643	Histidine kinase
JC774_18015	COG2198	Histidine kinase
JC774_18020	COG2201	protein-glutamate methylesterase activity
JC774_18030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JC774_18060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JC774_18065	COG2323	membrane
JC774_18070	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JC774_18075	COG0475	glutathione-regulated potassium exporter activity
JC774_18080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JC774_18085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC774_18090	COG3162	membrane
JC774_18100	COG1278	Cold shock
JC774_18135	COG0328	RNA-DNA hybrid ribonuclease activity
JC774_18155	COG1733	regulation of RNA biosynthetic process
JC774_18160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JC774_18170	COG3766	membrane
JC774_18210	COG0456	acetyltransferase
JC774_18220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JC774_18225	COG2311	Membrane
JC774_18230	COG2233	PERMEase
JC774_18235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JC774_18240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JC774_18245	COG1199	ATP-dependent helicase activity
JC774_18255	COG0116	Belongs to the methyltransferase superfamily
JC774_18265	COG3599	regulation of cell shape
JC774_18270	COG4474	Belongs to the UPF0398 family
JC774_18305	COG3331	DNA recombination
JC774_18310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC774_18310	COG4499	WXG100 protein secretion system (Wss), protein YukC
JC774_18320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JC774_18325	COG3935	DnaD domain protein
JC774_18345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JC774_18345	COG1199	ATP-dependent helicase activity
JC774_18350	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JC774_18355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JC774_18360	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JC774_18370	COG0617	tRNA 3'-terminal CCA addition
JC774_18375	COG0438	transferase activity, transferring glycosyl groups
JC774_18380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JC774_18385	COG1803	Methylglyoxal synthase
JC774_18390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JC774_18395	COG1694	Mazg nucleotide pyrophosphohydrolase
JC774_18400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC774_18410	COG2738	Putative neutral zinc metallopeptidase
JC774_18425	COG4347	Protein of unknown function (DUF1405)
JC774_18435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JC774_18450	COG5582	Belongs to the UPF0302 family
JC774_18455	COG0457	Tetratricopeptide repeat
JC774_18460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JC774_18465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JC774_18470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JC774_18475	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JC774_18485	COG0142	geranyltranstransferase activity
JC774_18490	COG2226	methyltransferase
JC774_18495	COG0142	geranyltranstransferase activity
JC774_18500	COG0302	gtp cyclohydrolase
JC774_18510	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JC774_18530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JC774_18535	COG1160	GTP binding
JC774_18560	COG1304	FMN binding
JC774_18570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JC774_18585	COG0492	ferredoxin-NADP+ reductase activity
JC774_18600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JC774_18615	COG1408	metallophosphoesterase
JC774_18625	COG1266	CAAX protease self-immunity
JC774_18630	COG0514	ATP-dependent DNA helicase (RecQ)
JC774_18640	COG1141	Ferredoxin
JC774_18645	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JC774_18660	COG2096	Adenosyltransferase
JC774_18665	COG5002	protein histidine kinase activity
JC774_18670	COG0745	RESPONSE REGULATOR receiver
JC774_18675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JC774_18680	COG1333	cytochrome c biogenesis protein
JC774_18690	COG1187	pseudouridine synthase activity
JC774_18695	COG0700	Nucleoside recognition
JC774_18700	COG2715	membrane protein required for spore maturation
JC774_18705	COG1686	Belongs to the peptidase S11 family
JC774_18710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JC774_18725	COG0392	lysyltransferase activity
JC774_18725	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JC774_18735	COG0813	purine-nucleoside phosphorylase activity
JC774_18740	COG5002	protein histidine kinase activity
JC774_18745	COG0582	viral genome integration into host DNA
JC774_18755	COG1801	Protein of unknown function DUF72
JC774_18760	COG3852	Histidine kinase
JC774_18770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC774_18775	COG1392	Phosphate transport regulator
JC774_18780	COG0306	phosphate transporter
JC774_18785	COG0730	response to heat
JC774_18805	COG2801	Transposase and inactivated derivatives
JC774_18815	COG1482	cell wall glycoprotein biosynthetic process
JC774_18820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC774_18820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC774_18820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JC774_18825	COG3711	transcriptional antiterminator
JC774_18825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JC774_18860	COG4085	toxin activity
JC774_18860	COG0737	Belongs to the 5'-nucleotidase family
JC774_18860	COG1525	nuclease
JC774_18865	COG1114	Component of the transport system for branched-chain amino acids
JC774_18870	COG2197	response regulator
JC774_18875	COG4585	Histidine kinase
JC774_18880	COG4758	membrane
JC774_18895	COG1757	Na H antiporter
JC774_18900	COG3557	Belongs to the UPF0374 family
JC774_18915	COG0733	neurotransmitter:sodium symporter activity
JC774_18920	COG1648	precorrin-2 dehydrogenase activity
JC774_18920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JC774_18940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JC774_18945	COG0529	Catalyzes the synthesis of activated sulfate
JC774_18950	COG2046	Belongs to the sulfate adenylyltransferase family
JC774_18955	COG0175	sulfate reduction
JC774_18965	COG0019	diaminopimelate decarboxylase activity
JC774_18975	COG1368	sulfuric ester hydrolase activity
JC774_18980	COG1183	phosphatidylcholine synthase activity
JC774_18995	COG0140	phosphoribosyl-ATP diphosphatase activity
JC774_19000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JC774_19005	COG0107	imidazoleglycerol-phosphate synthase activity
JC774_19010	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JC774_19015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JC774_19020	COG0131	Imidazoleglycerol-phosphate dehydratase
JC774_19030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JC774_19040	COG0066	3-isopropylmalate dehydratase activity
JC774_19045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JC774_19055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JC774_19060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JC774_19065	COG0440	acetolactate synthase activity
JC774_19070	COG0028	Belongs to the TPP enzyme family
JC774_19090	COG3874	Sporulation protein YtfJ
JC774_19100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC774_19105	COG1301	dicarboxylic acid transport
JC774_19115	COG1846	Transcriptional regulator
JC774_19130	COG0534	Mate efflux family protein
JC774_19135	COG0288	reversible hydration of carbon dioxide
JC774_19140	COG3002	Belongs to the UPF0753 family
JC774_19145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JC774_19150	COG5609	conserved protein (DUF2294)
JC774_19175	COG1368	sulfuric ester hydrolase activity
JC774_19200	COG0716	FMN binding
JC774_19215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JC774_19220	COG1696	Membrane protein involved in D-alanine export
JC774_19230	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JC774_19235	COG2070	2-Nitropropane dioxygenase
JC774_19240	COG1619	proteins homologs of microcin C7 resistance protein MccF
JC774_19260	COG1522	sequence-specific DNA binding
JC774_19275	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JC774_19280	COG1131	(ABC) transporter
JC774_19290	COG1131	(ABC) transporter
JC774_19295	COG1725	Transcriptional regulator
JC774_19300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JC774_19320	COG1780	Probably involved in ribonucleotide reductase function
JC774_19335	COG0456	acetyltransferase
JC774_19345	COG4873	Protein conserved in bacteria
JC774_19350	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JC774_19360	COG0720	synthase
JC774_19365	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JC774_19370	COG2318	DinB family
JC774_19380	COG1846	Transcriptional regulator
JC774_19385	COG3852	Histidine kinase
JC774_19395	COG2861	carbohydrate metabolic process
JC774_19405	COG0235	Class ii aldolase
JC774_19410	COG1349	DNA-binding transcription factor activity
JC774_19415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JC774_19420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JC774_19430	COG3842	ATPase activity
JC774_19435	COG1840	ABC-type Fe3 transport system, periplasmic component
JC774_19450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC774_19455	COG3243	poly(R)-hydroxyalkanoic acid synthase
JC774_19460	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_19480	COG2030	dehydratase
JC774_19490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JC774_19495	COG0861	Integral membrane protein TerC family
JC774_19500	COG2116	formate transmembrane transporter activity
JC774_19505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JC774_19510	COG2267	carboxylic ester hydrolase activity
JC774_19520	COG0584	glycerophosphoryl diester phosphodiesterase
JC774_19525	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JC774_19530	COG1556	Lactate utilization protein
JC774_19535	COG1139	Iron-sulfur cluster binding protein
JC774_19540	COG0247	lactate metabolic process
JC774_19545	COG2186	Transcriptional regulator
JC774_19550	COG5002	protein histidine kinase activity
JC774_19555	COG0745	RESPONSE REGULATOR receiver
JC774_19565	COG3835	regulator
JC774_19570	COG0277	FAD linked oxidase domain protein
JC774_19575	COG0247	lactate metabolic process
JC774_19580	COG2340	Cysteine-rich secretory protein family
JC774_19590	COG0564	pseudouridine synthase activity
JC774_19600	COG2409	Drug exporters of the RND superfamily
JC774_19605	COG0671	phosphoesterase, PA-phosphatase related
JC774_19610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JC774_19615	COG1177	transmembrane transport
JC774_19620	COG1176	ABC-type spermidine putrescine transport system, permease component I
JC774_19630	COG1012	belongs to the aldehyde dehydrogenase family
JC774_19670	COG0681	Belongs to the peptidase S26 family
JC774_19675	COG1686	Belongs to the peptidase S11 family
JC774_19690	COG0582	viral genome integration into host DNA
JC774_19775	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_19825	COG0179	Fumarylacetoacetate (FAA) hydrolase
JC774_19830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC774_19835	COG3162	membrane
JC774_19840	COG0196	riboflavin kinase activity
JC774_19855	COG1012	belongs to the aldehyde dehydrogenase family
JC774_19860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JC774_19865	COG0583	DNA-binding transcription factor activity
JC774_19875	COG0567	Dehydrogenase, E1 component
JC774_19880	COG0508	dehydrogenase complex catalyzes the overall conversion of
JC774_19920	COG5634	Uncharacterized conserved protein (DUF2278)
JC774_19925	COG1620	l-lactate permease
JC774_19935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC774_19940	COG5492	domain, Protein
JC774_19955	COG2382	esterase
JC774_19960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JC774_19985	COG1091	dTDP-4-dehydrorhamnose reductase activity
JC774_20000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JC774_20020	COG0463	Glycosyl transferase, family 2
JC774_20020	COG0457	Tetratricopeptide repeat
JC774_20040	COG1216	Glycosyl transferase, family 2
JC774_20085	COG0772	Belongs to the SEDS family
JC774_20090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JC774_20100	COG0564	pseudouridine synthase activity
JC774_20110	COG2357	RelA SpoT domain protein
JC774_20120	COG4116	CYTH
JC774_20125	COG2346	COG2346, Truncated hemoglobins
JC774_20135	COG1164	Oligoendopeptidase f
JC774_20155	COG0861	Integral membrane protein TerC family
JC774_20170	COG4166	transmembrane transport
JC774_20175	COG0534	Mate efflux family protein
JC774_20180	COG4608	Belongs to the ABC transporter superfamily
JC774_20185	COG0444	Belongs to the ABC transporter superfamily
JC774_20190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JC774_20195	COG0601	transmembrane transport
JC774_20200	COG4166	transmembrane transport
JC774_20210	COG0180	Tryptophanyl-tRNA synthetase
JC774_20220	COG5504	Zn-dependent protease
JC774_20225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JC774_20230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JC774_20245	COG2267	carboxylic ester hydrolase activity
JC774_20265	COG0561	phosphatase activity
JC774_20280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JC774_20295	COG2996	Protein conserved in bacteria
JC774_20300	COG1666	GTP binding
JC774_20305	COG1874	Beta-galactosidase
JC774_20305	COG0366	Alpha amylase catalytic
JC774_20310	COG0753	catalase activity
JC774_20320	COG0367	asparagine synthase
JC774_20340	COG0179	Fumarylacetoacetate (FAA) hydrolase
JC774_20380	COG1074	ATP-dependent DNA helicase activity
JC774_20385	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JC774_20395	COG0398	Pfam SNARE associated Golgi protein
JC774_20400	COG4903	ComK protein
JC774_20405	COG1278	Cold shock
JC774_20410	COG2224	Isocitrate lyase
JC774_20415	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JC774_20430	COG0697	spore germination
JC774_20435	COG0840	transmembrane signaling receptor activity
JC774_20440	COG0501	Belongs to the peptidase M48B family
JC774_20460	COG0745	RESPONSE REGULATOR receiver
JC774_20465	COG2205	protein histidine kinase activity
JC774_20480	COG0318	PFAM AMP-dependent synthetase and ligase
JC774_20490	COG0095	Lipoate-protein ligase
JC774_20495	COG1234	tRNA 3'-trailer cleavage
JC774_20505	COG1609	Transcriptional regulator
JC774_20520	COG1216	Glycosyl transferase, family 2
JC774_20520	COG0438	transferase activity, transferring glycosyl groups
JC774_20530	COG1309	transcriptional regulator
JC774_20555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JC774_20560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JC774_20565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JC774_20570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JC774_20575	COG2329	Antibiotic biosynthesis monooxygenase
JC774_20585	COG3402	PFAM membrane-flanked domain
JC774_20605	COG4473	ABC transporter
JC774_20610	COG1131	(ABC) transporter
JC774_20615	COG0537	adenosine 5'-monophosphoramidase activity
JC774_20620	COG4980	gas vesicle protein
JC774_20625	COG1846	Transcriptional regulator
JC774_20645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JC774_20650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JC774_20655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JC774_20660	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JC774_20670	COG1316	TRANSCRIPTIONal
JC774_20680	COG0745	RESPONSE REGULATOR receiver
JC774_20685	COG5002	protein histidine kinase activity
JC774_20695	COG1136	(ABC) transporter
JC774_20700	COG0577	efflux transmembrane transporter activity
JC774_20835	COG4653	Phage capsid family
JC774_20840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JC774_20855	COG1783	phage Terminase large subunit
JC774_20860	COG5484	DNA packaging
JC774_20905	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JC774_21040	COG1396	sequence-specific DNA binding
JC774_21050	COG4974	Belongs to the 'phage' integrase family
JC774_21055	COG3481	metal-dependent phosphohydrolase, HD sub domain
JC774_21060	COG4717	serine-type aminopeptidase activity
JC774_21065	COG0420	3'-5' exonuclease activity
JC774_21100	COG2376	Dihydroxyacetone kinase
JC774_21110	COG2723	6-phospho-beta-galactosidase activity
JC774_21115	COG2190	(PTS) system
JC774_21115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC774_21115	COG1263	PTS System
JC774_21120	COG3711	transcriptional antiterminator
JC774_21135	COG4641	Protein conserved in bacteria
JC774_21180	COG3246	L-lysine catabolic process to acetate
JC774_21195	COG1064	alcohol dehydrogenase
JC774_21205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JC774_21215	COG0473	3-isopropylmalate dehydrogenase activity
JC774_21220	COG1012	belongs to the aldehyde dehydrogenase family
JC774_21225	COG4638	Rieske (2fe-2S)
JC774_21230	COG3829	transcription factor binding
JC774_21235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JC774_21240	COG1472	Belongs to the glycosyl hydrolase 3 family
JC774_21250	COG4978	Transcriptional regulator
JC774_21250	COG0789	Transcriptional regulator
JC774_21360	COG5444	nuclease activity
JC774_21390	COG1115	amino acid carrier protein
JC774_21400	COG2239	Acts as a magnesium transporter
JC774_21415	COG1363	Peptidase, m42
JC774_21425	COG1024	Enoyl-CoA hydratase
JC774_21440	COG1696	Membrane protein involved in D-alanine export
JC774_21470	COG2244	polysaccharide biosynthetic process
JC774_21500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JC774_21515	COG0561	phosphatase activity
JC774_21520	COG2094	Belongs to the DNA glycosylase MPG family
JC774_21525	COG3527	Alpha-acetolactate decarboxylase
JC774_21530	COG0028	Belongs to the TPP enzyme family
JC774_21570	COG2197	response regulator
JC774_21575	COG4585	Histidine kinase
JC774_21580	COG3679	Belongs to the UPF0342 family
JC774_21585	COG4399	Belongs to the UPF0754 family
JC774_21590	COG0189	ligase activity
JC774_21605	COG1126	abc transporter atp-binding protein
JC774_21610	COG0765	amino acid transport
JC774_21615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JC774_21620	COG1132	(ABC) transporter
JC774_21625	COG1132	(ABC) transporter
JC774_21630	COG1012	belongs to the aldehyde dehydrogenase family
JC774_21635	COG0531	amino acid
JC774_21650	COG1522	sequence-specific DNA binding
JC774_21665	COG1263	PTS System
JC774_21665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JC774_21670	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JC774_21680	COG1737	Transcriptional regulator
JC774_21685	COG0475	glutathione-regulated potassium exporter activity
JC774_21740	COG3546	catalase activity
JC774_21745	COG1114	Component of the transport system for branched-chain amino acids
JC774_21750	COG5522	Integral membrane protein (intg_mem_TP0381)
JC774_21760	COG1136	(ABC) transporter
JC774_21765	COG0577	efflux transmembrane transporter activity
JC774_21780	COG1283	sodium-dependent phosphate transmembrane transporter activity
JC774_21785	COG1316	TRANSCRIPTIONal
JC774_21805	COG2719	SpoVR family
JC774_21815	COG0778	Nitroreductase
JC774_21870	COG1376	ErfK ybiS ycfS ynhG family protein
JC774_21875	COG1028	Short-chain dehydrogenase reductase Sdr
JC774_21880	COG2252	PERMEase
JC774_21890	COG1846	Transcriptional regulator
JC774_21895	COG2814	Major facilitator Superfamily
JC774_21900	COG2205	protein histidine kinase activity
JC774_21905	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JC774_21910	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JC774_21940	COG0351	phosphomethylpyrimidine kinase
JC774_21945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JC774_21950	COG2022	thiamine diphosphate biosynthetic process
JC774_21955	COG2104	thiamine diphosphate biosynthetic process
JC774_21960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JC774_21965	COG0352	thiamine-phosphate diphosphorylase activity
JC774_21970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JC774_21975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JC774_21980	COG1116	anion transmembrane transporter activity
JC774_21985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway