locus-tag	class	description
LLY41_00020	COG0726	polysaccharide deacetylase
LLY41_00025	COG2194	sulfuric ester hydrolase activity
LLY41_00035	COG0489	protein tyrosine kinase activity
LLY41_00040	COG0860	N-Acetylmuramoyl-L-alanine amidase
LLY41_00050	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LLY41_00055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LLY41_00060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLY41_00070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LLY41_00075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LLY41_00080	COG0101	tRNA pseudouridine synthase activity
LLY41_00085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LLY41_00090	COG1122	ATPase activity
LLY41_00095	COG1122	ATPase activity
LLY41_00100	COG0203	ribosomal protein L17
LLY41_00105	COG0202	RNA polymerase activity
LLY41_00115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LLY41_00120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LLY41_00125	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LLY41_00130	COG2163	COG2163 Ribosomal protein L14E L6E L27E
LLY41_00135	COG0024	Methionine aminopeptidase
LLY41_00140	COG0563	adenylate kinase activity
LLY41_00145	COG0201	protein transport
LLY41_00155	COG1841	ribosomal large subunit assembly
LLY41_00160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LLY41_00165	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LLY41_00170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LLY41_00185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LLY41_00190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LLY41_00195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LLY41_00210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LLY41_00215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LLY41_00225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LLY41_00230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LLY41_00240	COG0088	Forms part of the polypeptide exit tunnel
LLY41_00245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LLY41_00250	COG0051	transcription antitermination factor activity, RNA binding
LLY41_00255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LLY41_00270	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LLY41_00275	COG1358	cellular component organization or biogenesis
LLY41_00280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LLY41_00290	COG2813	Specifically methylates the guanine in position
LLY41_00295	COG0222	ribosome binding
LLY41_00300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LLY41_00305	COG0081	regulation of translation
LLY41_00310	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LLY41_00315	COG0250	Participates in transcription elongation, termination and antitermination
LLY41_00320	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LLY41_00325	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLY41_00335	COG3688	RNA-binding protein containing a PIN domain
LLY41_00340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLY41_00350	COG0215	cysteine-tRNA ligase activity
LLY41_00355	COG1045	serine acetyltransferase
LLY41_00360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LLY41_00370	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LLY41_00375	COG4956	integral membrane protein (PIN domain superfamily)
LLY41_00380	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LLY41_00390	COG0542	response to heat
LLY41_00395	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LLY41_00400	COG3880	PFAM UvrB UvrC protein
LLY41_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LLY41_00490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LLY41_00495	COG1396	sequence-specific DNA binding
LLY41_00500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LLY41_00505	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LLY41_00510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LLY41_00515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LLY41_00520	COG0512	Glutamine amidotransferase of anthranilate synthase
LLY41_00530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LLY41_00535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLY41_00540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LLY41_00545	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LLY41_00550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLY41_00555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LLY41_00565	COG0515	serine threonine protein kinase
LLY41_00570	COG2304	oxidoreductase activity
LLY41_00575	COG2208	phosphoserine phosphatase activity
LLY41_00590	COG1098	S1 RNA binding domain
LLY41_00610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LLY41_00615	COG3956	TIGRFAM MazG family protein
LLY41_00620	COG2244	polysaccharide biosynthetic process
LLY41_00625	COG2002	toxin-antitoxin pair type II binding
LLY41_00630	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LLY41_00645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LLY41_00655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LLY41_00665	COG0251	oxidation-reduction process
LLY41_00670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLY41_00685	COG4466	Protein conserved in bacteria
LLY41_00695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LLY41_00705	COG3584	3D domain protein
LLY41_00705	COG3583	domain protein
LLY41_00710	COG0084	hydrolase, TatD family'
LLY41_00720	COG2002	toxin-antitoxin pair type II binding
LLY41_00725	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LLY41_00735	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LLY41_00740	COG4467	Involved in initiation control of chromosome replication
LLY41_00745	COG1774	PSP1 C-terminal conserved region
LLY41_00750	COG0470	DNA polymerase III
LLY41_00755	COG1728	Protein conserved in bacteria
LLY41_00760	COG3870	Protein conserved in bacteria
LLY41_00765	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LLY41_00770	COG1982	Orn Lys Arg decarboxylase major
LLY41_00815	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LLY41_00820	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LLY41_00825	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LLY41_00835	COG0590	tRNA wobble adenosine to inosine editing
LLY41_00840	COG1335	isochorismatase
LLY41_00845	COG3858	chitin binding
LLY41_00845	COG1388	LysM domain
LLY41_00850	COG1428	Deoxynucleoside kinase
LLY41_00855	COG1428	Deoxynucleoside kinase
LLY41_00870	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LLY41_00885	COG0516	GMP reductase activity
LLY41_00885	COG0517	IMP dehydrogenase activity
LLY41_00930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LLY41_00935	COG0187	DNA topoisomerase II activity
LLY41_00945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LLY41_00950	COG2501	S4 domain
LLY41_00955	COG0592	DNA-directed DNA polymerase activity
LLY41_00965	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LLY41_00970	COG0594	ribonuclease P activity
LLY41_00980	COG1847	R3H domain protein
LLY41_00985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LLY41_00990	COG0445	tRNA wobble uridine modification
LLY41_00995	COG0357	Ribosomal RNA small subunit methyltransferase G
LLY41_01000	COG1475	DNA binding
LLY41_01005	COG1192	Involved in chromosome partitioning
LLY41_01025	COG0668	transmembrane transport
LLY41_01030	COG4481	Protein conserved in bacteria
LLY41_01035	COG0243	molybdopterin cofactor binding
LLY41_01040	COG0012	GTP binding
LLY41_01045	COG0360	Binds together with S18 to 16S ribosomal RNA
LLY41_01050	COG0629	single-stranded DNA binding
LLY41_01055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LLY41_01060	COG4241	membrane
LLY41_01065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LLY41_01070	COG0359	binds to the 23S rRNA
LLY41_01075	COG0305	Participates in initiation and elongation during chromosome replication
LLY41_01080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LLY41_01110	COG0745	RESPONSE REGULATOR receiver
LLY41_01115	COG5002	protein histidine kinase activity
LLY41_01120	COG4863	YycH protein
LLY41_01125	COG4853	Protein conserved in bacteria
LLY41_01130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LLY41_01135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LLY41_01145	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LLY41_01170	COG0732	type I restriction modification DNA specificity domain
LLY41_01210	COG5444	nuclease activity
LLY41_01255	COG5444	nuclease activity
LLY41_01275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LLY41_01295	COG1187	pseudouridine synthase activity
LLY41_01330	COG1846	Transcriptional regulator
LLY41_01355	COG5002	protein histidine kinase activity
LLY41_01360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LLY41_01365	COG0583	DNA-binding transcription factor activity
LLY41_01380	COG2814	Major facilitator Superfamily
LLY41_01385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLY41_01390	COG1027	Aspartate ammonia-lyase
LLY41_01395	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LLY41_01405	COG1070	Carbohydrate kinase
LLY41_01420	COG0579	oxidoreductase
LLY41_01425	COG3620	sequence-specific DNA binding
LLY41_01430	COG3708	Transcriptional regulator
LLY41_01430	COG2207	Transcriptional regulator
LLY41_01480	COG1404	Belongs to the peptidase S8 family
LLY41_01490	COG3227	Zinc metalloprotease (Elastase)
LLY41_01500	COG0681	Belongs to the peptidase S26 family
LLY41_01510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLY41_01535	COG2321	neutral zinc metallopeptidase
LLY41_01540	COG4297	protein containing double-stranded beta helix domain
LLY41_01545	COG3104	oligopeptide transport
LLY41_01550	COG2199	diguanylate cyclase activity
LLY41_01565	COG0492	ferredoxin-NADP+ reductase activity
LLY41_01580	COG0366	Alpha amylase catalytic
LLY41_01585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LLY41_01600	COG3314	Sporulation integral membrane protein YlbJ
LLY41_01615	COG4555	ABC transporter
LLY41_01625	COG2031	fatty acid transporter
LLY41_01640	COG0561	phosphatase activity
LLY41_01645	COG2133	pyrroloquinoline quinone binding
LLY41_01655	COG0842	Transport permease protein
LLY41_01655	COG1511	domain protein
LLY41_01660	COG1131	(ABC) transporter
LLY41_01665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLY41_01680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LLY41_01685	COG0351	phosphomethylpyrimidine kinase
LLY41_01695	COG0746	molybdenum cofactor guanylyltransferase activity
LLY41_01700	COG0314	molybdopterin synthase activity
LLY41_01705	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LLY41_01710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LLY41_01725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LLY41_01740	COG2363	Small membrane protein
LLY41_01750	COG3253	May function as heme-dependent peroxidase
LLY41_01755	COG0280	phosphate acetyltransferase
LLY41_01770	COG4844	belongs to the
LLY41_01775	COG1078	dGTPase activity
LLY41_01780	COG3465	dGTPase activity
LLY41_01790	COG1994	Peptidase M50
LLY41_01805	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LLY41_01810	COG0010	Belongs to the arginase family
LLY41_01815	COG4506	Protein conserved in bacteria
LLY41_01820	COG0018	arginyl-trna synthetase
LLY41_01830	COG0697	spore germination
LLY41_01835	COG4294	response to UV
LLY41_01840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLY41_01845	COG2181	nitrate reductase activity
LLY41_01845	COG0247	lactate metabolic process
LLY41_01855	COG1250	3-hydroxyacyl-CoA dehydrogenase
LLY41_01860	COG1960	acyl-CoA dehydrogenase activity
LLY41_01865	COG1960	acyl-CoA dehydrogenase activity
LLY41_01875	COG1703	isobutyryl-CoA mutase activity
LLY41_01875	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LLY41_01875	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LLY41_01885	COG3343	RNA polymerase activity
LLY41_01890	COG0504	CTP synthase activity
LLY41_01895	COG4821	SIS domain
LLY41_01900	COG2204	response regulator
LLY41_01905	COG0191	fructose-bisphosphate aldolase activity
LLY41_01910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LLY41_01920	COG1494	fructose-1,6-bisphosphatase
LLY41_01925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LLY41_01940	COG1435	thymidine kinase activity
LLY41_01950	COG0697	spore germination
LLY41_01955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LLY41_01980	COG0009	L-threonylcarbamoyladenylate synthase
LLY41_01985	COG1971	Probably functions as a manganese efflux pump
LLY41_01995	COG0840	transmembrane signaling receptor activity
LLY41_02000	COG0698	ribose 5-phosphate isomerase
LLY41_02005	COG4475	Protein of unknown function (DUF436)
LLY41_02010	COG1595	DNA-templated transcription, initiation
LLY41_02020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LLY41_02025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LLY41_02030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LLY41_02045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLY41_02065	COG0356	it plays a direct role in the translocation of protons across the membrane
LLY41_02070	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LLY41_02075	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LLY41_02080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LLY41_02085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LLY41_02090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LLY41_02095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LLY41_02100	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LLY41_02105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LLY41_02120	COG1388	LysM domain
LLY41_02120	COG3584	3D domain protein
LLY41_02125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LLY41_02130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LLY41_02140	COG0649	NAD binding
LLY41_02145	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LLY41_02150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LLY41_02155	COG0839	Belongs to the complex I subunit 6 family
LLY41_02160	COG0713	ATP synthesis coupled electron transport
LLY41_02165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LLY41_02170	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LLY41_02175	COG1007	ATP synthesis coupled electron transport
LLY41_02180	COG4836	Membrane
LLY41_02200	COG2385	sporulation resulting in formation of a cellular spore
LLY41_02210	COG0739	heme binding
LLY41_02215	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LLY41_02230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LLY41_02240	COG0617	tRNA 3'-terminal CCA addition
LLY41_02240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LLY41_02240	COG0517	IMP dehydrogenase activity
LLY41_02245	COG2176	DNA-directed DNA polymerase activity
LLY41_02250	COG1388	LysM domain
LLY41_02250	COG0791	NLP P60 protein
LLY41_02255	COG1609	Transcriptional regulator
LLY41_02260	COG1077	Cell shape determining protein MreB Mrl
LLY41_02265	COG4786	Flagellar basal body rod
LLY41_02270	COG4786	Flagellar basal body rod
LLY41_02295	COG0629	single-stranded DNA binding
LLY41_02320	COG4715	Zinc finger, swim domain protein
LLY41_02335	COG0840	transmembrane signaling receptor activity
LLY41_02345	COG2188	Transcriptional regulator
LLY41_02365	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LLY41_02370	COG0626	cystathionine gamma-synthase activity
LLY41_02375	COG3457	Alanine racemase
LLY41_02380	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LLY41_02390	COG3409	Peptidoglycan-binding domain 1 protein
LLY41_02390	COG3773	Cell wall hydrolase
LLY41_02395	COG3584	3D domain protein
LLY41_02395	COG1388	LysM domain
LLY41_02400	COG5001	Diguanylate cyclase
LLY41_02400	COG3300	MHYT domain
LLY41_02425	COG1175	transmembrane transport
LLY41_02430	COG0395	ABC-type sugar transport system, permease component
LLY41_02435	COG0445	tRNA wobble uridine modification
LLY41_02440	COG0366	Alpha amylase catalytic
LLY41_02500	COG1609	Transcriptional regulator
LLY41_02520	COG0395	ABC-type sugar transport system, permease component
LLY41_02545	COG0840	transmembrane signaling receptor activity
LLY41_02570	COG0768	penicillin binding
LLY41_02600	COG1388	LysM domain
LLY41_02600	COG0791	NLP P60 protein
LLY41_02645	COG2003	Belongs to the UPF0758 family
LLY41_02655	COG4974	Belongs to the 'phage' integrase family
LLY41_02725	COG2247	cell wall binding repeat
LLY41_02725	COG0860	N-Acetylmuramoyl-L-alanine amidase
LLY41_02740	COG0653	protein targeting
LLY41_02755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LLY41_02760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LLY41_02775	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LLY41_02780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LLY41_02785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LLY41_02795	COG4193	domain, Protein
LLY41_02795	COG5263	repeat protein
LLY41_02805	COG1134	teichoic acid transport
LLY41_02815	COG1368	sulfuric ester hydrolase activity
LLY41_02825	COG0463	Glycosyl transferase, family 2
LLY41_02825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LLY41_02830	COG0438	transferase activity, transferring glycosyl groups
LLY41_02835	COG0728	peptidoglycan biosynthetic process
LLY41_02840	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LLY41_02850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLY41_02860	COG1316	TRANSCRIPTIONal
LLY41_02865	COG1739	Uncharacterized protein family UPF0029
LLY41_02870	COG4585	Histidine kinase
LLY41_02875	COG2197	response regulator
LLY41_02890	COG1307	EDD domain protein, DegV family
LLY41_02895	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LLY41_02900	COG1040	competence protein
LLY41_02905	COG5001	Diguanylate cyclase
LLY41_02940	COG1728	Protein conserved in bacteria
LLY41_02955	COG4786	Flagellar basal body rod
LLY41_02955	COG1256	bacterial-type flagellum assembly
LLY41_02960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LLY41_02970	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LLY41_02975	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LLY41_02990	COG1086	Polysaccharide biosynthesis protein
LLY41_03000	COG0275	rRNA processing
LLY41_03010	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LLY41_03015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LLY41_03020	COG1215	transferase activity, transferring glycosyl groups
LLY41_03025	COG0662	Cupin 2, conserved barrel domain protein
LLY41_03025	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LLY41_03035	COG1442	glycosyl transferase family 8
LLY41_03045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LLY41_03055	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_03080	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LLY41_03090	COG2089	acid synthase
LLY41_03095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LLY41_03100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LLY41_03110	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LLY41_03115	COG1516	flagellar protein fliS
LLY41_03135	COG0840	transmembrane signaling receptor activity
LLY41_03140	COG1744	ABC transporter substrate-binding protein PnrA-like
LLY41_03160	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LLY41_03170	COG2059	Chromate
LLY41_03175	COG2059	Chromate
LLY41_03185	COG1405	negative regulation of cell septum assembly
LLY41_03185	COG3012	SEC-C Motif Domain Protein
LLY41_03200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LLY41_03205	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LLY41_03205	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LLY41_03210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LLY41_03210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LLY41_03215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LLY41_03220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LLY41_03225	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LLY41_03235	COG0129	dihydroxy-acid dehydratase activity
LLY41_03240	COG1414	Transcriptional regulator
LLY41_03250	COG2721	sulfolactate sulfo-lyase activity
LLY41_03255	COG2721	sulfolactate sulfo-lyase activity
LLY41_03260	COG1012	belongs to the aldehyde dehydrogenase family
LLY41_03265	COG4948	Mandelate Racemase Muconate Lactonizing
LLY41_03270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LLY41_03280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LLY41_03290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LLY41_03295	COG0800	Aldolase
LLY41_03300	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LLY41_03305	COG1691	(AIR) carboxylase
LLY41_03310	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LLY41_03315	COG1606	tRNA processing
LLY41_03330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLY41_03340	COG2884	Cell division ATP-binding protein ftsE
LLY41_03345	COG2177	Part of the ABC transporter FtsEX involved in
LLY41_03350	COG0791	NLP P60 protein
LLY41_03350	COG3883	PFAM NLP P60 protein
LLY41_03355	COG0793	Belongs to the peptidase S41A family
LLY41_03355	COG3409	Peptidoglycan-binding domain 1 protein
LLY41_03360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LLY41_03370	COG0628	permease
LLY41_03380	COG4191	Histidine kinase
LLY41_03385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LLY41_03390	COG2011	ABC-type metal ion transport system permease component
LLY41_03395	COG1464	Belongs to the NlpA lipoprotein family
LLY41_03410	COG4897	Protein conserved in bacteria
LLY41_03415	COG0556	nucleotide-excision repair
LLY41_03420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LLY41_03440	COG3595	metallopeptidase activity
LLY41_03445	COG1983	PspC domain protein
LLY41_03450	COG1950	PFAM Membrane protein of
LLY41_03465	COG2188	Transcriptional regulator
LLY41_03470	COG0363	glucosamine-6-phosphate deaminase activity
LLY41_03475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LLY41_03490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLY41_03490	COG1263	PTS System
LLY41_03495	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LLY41_03505	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LLY41_03515	COG0110	maltose O-acetyltransferase activity
LLY41_03520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LLY41_03525	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LLY41_03530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LLY41_03535	COG0131	Imidazoleglycerol-phosphate dehydratase
LLY41_03540	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LLY41_03545	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LLY41_03550	COG0107	imidazoleglycerol-phosphate synthase activity
LLY41_03555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LLY41_03555	COG0140	phosphoribosyl-ATP diphosphatase activity
LLY41_03565	COG0457	Tetratricopeptide repeat
LLY41_03570	COG0492	ferredoxin-NADP+ reductase activity
LLY41_03575	COG1051	belongs to the nudix hydrolase family
LLY41_03580	COG1660	Displays ATPase and GTPase activities
LLY41_03585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LLY41_03595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLY41_03600	COG0740	serine-type endopeptidase activity
LLY41_03610	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LLY41_03640	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LLY41_03650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LLY41_03655	COG1647	Serine aminopeptidase, S33
LLY41_03660	COG0557	exoribonuclease II activity
LLY41_03665	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LLY41_03680	COG1309	transcriptional regulator
LLY41_03695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LLY41_03700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LLY41_03705	COG0668	transmembrane transport
LLY41_03710	COG0655	NAD(P)H dehydrogenase (quinone) activity
LLY41_03715	COG1785	Belongs to the alkaline phosphatase family
LLY41_03725	COG1846	Transcriptional regulator
LLY41_03730	COG2409	Drug exporters of the RND superfamily
LLY41_03730	COG1033	growth of symbiont in host cell
LLY41_03735	COG0300	oxidoreductase activity
LLY41_03745	COG0242	peptide deformylase activity
LLY41_03765	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_03770	COG0860	N-Acetylmuramoyl-L-alanine amidase
LLY41_03815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LLY41_03820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLY41_03825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLY41_03830	COG1120	ATPase activity
LLY41_03845	COG5577	PFAM Coat F domain
LLY41_03860	COG1024	Enoyl-CoA hydratase
LLY41_03860	COG1250	3-hydroxyacyl-CoA dehydrogenase
LLY41_03865	COG0183	Belongs to the thiolase family
LLY41_03870	COG1960	acyl-CoA dehydrogenase activity
LLY41_03875	COG1393	Belongs to the ArsC family
LLY41_03880	COG0509	glycine decarboxylation via glycine cleavage system
LLY41_03890	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LLY41_03895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLY41_03905	COG2873	o-acetylhomoserine
LLY41_03910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LLY41_03915	COG2011	ABC-type metal ion transport system permease component
LLY41_03920	COG1464	Belongs to the NlpA lipoprotein family
LLY41_03925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLY41_03935	COG0396	ATPase activity
LLY41_03940	COG0719	Fe-S assembly protein
LLY41_03945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LLY41_03950	COG0822	iron-sulfur transferase activity
LLY41_03955	COG0719	Fe-S assembly protein
LLY41_03965	COG3377	Domain of unknown function (DUF1805)
LLY41_03980	COG1757	Na H antiporter
LLY41_03985	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
LLY41_03990	COG0733	neurotransmitter:sodium symporter activity
LLY41_04000	COG0739	heme binding
LLY41_04015	COG4470	Protein conserved in bacteria
LLY41_04030	COG2445	Protein of unknown function DUF86
LLY41_04040	COG0647	UMP catabolic process
LLY41_04045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LLY41_04050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LLY41_04055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLY41_04060	COG0460	homoserine dehydrogenase
LLY41_04065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LLY41_04080	COG4837	Protein of unknown function (DUF1462)
LLY41_04085	COG1252	NADH dehydrogenase
LLY41_04090	COG4844	belongs to the
LLY41_04100	COG0316	Belongs to the HesB IscA family
LLY41_04110	COG1252	NADH dehydrogenase
LLY41_04115	COG0494	nUDIX hydrolase
LLY41_04130	COG3584	3D domain protein
LLY41_04140	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LLY41_04155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LLY41_04160	COG2056	Na+-H+ antiporter family
LLY41_04165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LLY41_04170	COG0789	Transcriptional regulator
LLY41_04180	COG3243	poly(R)-hydroxyalkanoic acid synthase
LLY41_04190	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_04205	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LLY41_04205	COG2508	Transcriptional regulator
LLY41_04210	COG0686	Belongs to the AlaDH PNT family
LLY41_04235	COG2050	protein possibly involved in aromatic compounds catabolism
LLY41_04240	COG1320	monovalent cation:proton antiporter activity
LLY41_04245	COG2212	antiporter activity
LLY41_04250	COG1863	multisubunit Na H antiporter MnhE subunit
LLY41_04260	COG1006	Multisubunit Na H antiporter MnhC subunit
LLY41_04265	COG2111	Na H antiporter
LLY41_04270	COG2111	Na H antiporter
LLY41_04270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LLY41_04285	COG5018	Exonuclease
LLY41_04295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LLY41_04305	COG2032	superoxide dismutase activity
LLY41_04315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LLY41_04325	COG2267	carboxylic ester hydrolase activity
LLY41_04330	COG1522	sequence-specific DNA binding
LLY41_04335	COG0436	Aminotransferase
LLY41_04345	COG1098	S1 RNA binding domain
LLY41_04350	COG1757	Na H antiporter
LLY41_04360	COG3829	transcription factor binding
LLY41_04365	COG1012	belongs to the aldehyde dehydrogenase family
LLY41_04370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LLY41_04375	COG2155	Conserved Protein
LLY41_04380	COG1979	alcohol dehydrogenase
LLY41_04405	COG2234	aminopeptidase activity
LLY41_04410	COG2936	dipeptidyl-peptidase activity
LLY41_04415	COG2112	serine threonine protein kinase
LLY41_04420	COG0702	epimerase
LLY41_04430	COG1271	oxidase subunit
LLY41_04435	COG1294	oxidase, subunit
LLY41_04445	COG1285	pathogenesis
LLY41_04580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LLY41_04590	COG0297	glycogen (starch) synthase activity
LLY41_04600	COG1834	amidinotransferase
LLY41_04610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LLY41_04615	COG1575	Belongs to the MenA family. Type 1 subfamily
LLY41_04620	COG1169	isochorismate synthase
LLY41_04625	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LLY41_04630	COG0596	Alpha beta hydrolase
LLY41_04635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LLY41_04640	COG0318	PFAM AMP-dependent synthetase and ligase
LLY41_04645	COG4948	Mandelate Racemase Muconate Lactonizing
LLY41_04665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LLY41_04670	COG1854	S-ribosylhomocysteine lyase activity
LLY41_04675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLY41_04685	COG0783	Belongs to the Dps family
LLY41_04705	COG0494	nUDIX hydrolase
LLY41_04710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LLY41_04715	COG1116	anion transmembrane transporter activity
LLY41_04720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LLY41_04725	COG1506	peptidase
LLY41_04745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LLY41_04750	COG0367	asparagine synthase
LLY41_04755	COG4990	cell redox homeostasis
LLY41_04760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LLY41_04765	COG2267	carboxylic ester hydrolase activity
LLY41_04775	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LLY41_04780	COG1242	4 iron, 4 sulfur cluster binding
LLY41_04810	COG2610	gluconate transmembrane transporter activity
LLY41_04815	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_04825	COG0495	leucyl-tRNA aminoacylation
LLY41_04830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLY41_04840	COG2081	HI0933 family
LLY41_04845	COG2244	polysaccharide biosynthetic process
LLY41_04850	COG1187	pseudouridine synthase activity
LLY41_04855	COG1349	DNA-binding transcription factor activity
LLY41_04865	COG1131	(ABC) transporter
LLY41_04870	COG4473	ABC transporter
LLY41_04875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LLY41_04885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LLY41_04900	COG1597	lipid kinase activity
LLY41_04920	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LLY41_04930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLY41_04935	COG5584	Small secreted protein
LLY41_04940	COG1363	Peptidase, m42
LLY41_04945	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LLY41_04970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLY41_04975	COG4848	Belongs to the UPF0354 family
LLY41_04980	COG1674	ftsk spoiiie
LLY41_04995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LLY41_05000	COG2309	aminopeptidase activity
LLY41_05005	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LLY41_05010	COG4980	gas vesicle protein
LLY41_05015	COG3118	belongs to the thioredoxin family
LLY41_05025	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LLY41_05025	COG1605	Chorismate mutase
LLY41_05045	COG0123	including yeast histone deacetylase and acetoin utilization protein
LLY41_05050	COG0517	IMP dehydrogenase activity
LLY41_05055	COG0454	-acetyltransferase
LLY41_05060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LLY41_05075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LLY41_05090	COG1956	GAF domain-containing protein
LLY41_05095	COG1309	transcriptional regulator
LLY41_05100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LLY41_05105	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LLY41_05110	COG1114	Component of the transport system for branched-chain amino acids
LLY41_05115	COG1104	cysteine desulfurase activity
LLY41_05120	COG0301	tRNA thio-modification
LLY41_05140	COG2962	Rard protein
LLY41_05145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LLY41_05150	COG0616	signal peptide processing
LLY41_05155	COG1714	RDD family
LLY41_05165	COG3874	Sporulation protein YtfJ
LLY41_05170	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LLY41_05175	COG0827	DNA restriction-modification system
LLY41_05180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLY41_05190	COG0521	Mo-molybdopterin cofactor biosynthetic process
LLY41_05200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLY41_05205	COG0137	argininosuccinate synthase activity
LLY41_05210	COG0165	Argininosuccinate lyase
LLY41_05215	COG0589	response to stress
LLY41_05230	COG0006	proline dipeptidase activity
LLY41_05235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LLY41_05245	COG4109	DRTGG domain
LLY41_05255	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LLY41_05275	COG0281	malic enzyme
LLY41_05280	COG2186	Transcriptional regulator
LLY41_05285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LLY41_05290	COG0825	malonyl-CoA metabolic process
LLY41_05295	COG0205	6-phosphofructokinase activity
LLY41_05305	COG3030	protein affecting phage T7 exclusion by the F plasmid
LLY41_05315	COG2707	UPF0756 membrane protein
LLY41_05320	COG0372	Belongs to the citrate synthase family
LLY41_05325	COG0538	isocitrate dehydrogenase activity
LLY41_05330	COG0039	L-malate dehydrogenase activity
LLY41_05340	COG0745	RESPONSE REGULATOR receiver
LLY41_05345	COG5002	protein histidine kinase activity
LLY41_05350	COG0330	HflC and HflK could
LLY41_05355	COG0330	HflC and HflK could
LLY41_05360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLY41_05360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLY41_05365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LLY41_05370	COG1971	Probably functions as a manganese efflux pump
LLY41_05375	COG0237	dephospho-CoA kinase activity
LLY41_05380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LLY41_05385	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LLY41_05395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LLY41_05400	COG3611	Membrane attachment protein
LLY41_05405	COG1484	DNA-dependent DNA replication
LLY41_05415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LLY41_05420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LLY41_05430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LLY41_05435	COG3326	Membrane
LLY41_05455	COG1363	Peptidase, m42
LLY41_05465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLY41_05470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LLY41_05475	COG0072	phenylalanine-tRNA ligase activity
LLY41_05475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLY41_05480	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LLY41_05485	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LLY41_05490	COG1286	toxin biosynthetic process
LLY41_05495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LLY41_05495	COG1796	DNA polymerase
LLY41_05505	COG3766	membrane
LLY41_05510	COG0318	PFAM AMP-dependent synthetase and ligase
LLY41_05515	COG1309	transcriptional regulator
LLY41_05520	COG1024	Enoyl-CoA hydratase
LLY41_05525	COG2086	electron transfer activity
LLY41_05530	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LLY41_05535	COG3118	belongs to the thioredoxin family
LLY41_05540	COG0322	excinuclease ABC activity
LLY41_05550	COG1719	4-vinyl reductase, 4VR
LLY41_05555	COG2009	succinate dehydrogenase
LLY41_05565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LLY41_05570	COG0824	Thioesterase
LLY41_05575	COG2197	response regulator
LLY41_05580	COG1846	Transcriptional regulator
LLY41_05590	COG0514	ATP-dependent DNA helicase (RecQ)
LLY41_05595	COG5401	PFAM Sporulation and spore germination
LLY41_05605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LLY41_05610	COG0622	Phosphoesterase
LLY41_05620	COG0028	Belongs to the TPP enzyme family
LLY41_05625	COG0440	acetolactate synthase activity
LLY41_05630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LLY41_05635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LLY41_05640	COG0473	3-isopropylmalate dehydrogenase activity
LLY41_05645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LLY41_05650	COG0066	3-isopropylmalate dehydratase activity
LLY41_05655	COG0457	Tetratricopeptide repeat
LLY41_05655	COG1477	protein flavinylation
LLY41_05660	COG0544	peptidyl-prolyl cis-trans isomerase activity
LLY41_05665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LLY41_05670	COG1067	ATP-dependent peptidase activity
LLY41_05670	COG0470	DNA polymerase III
LLY41_05675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LLY41_05685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLY41_05690	COG0765	amino acid transport
LLY41_05710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LLY41_05715	COG0181	hydroxymethylbilane synthase activity
LLY41_05725	COG0113	porphobilinogen synthase activity
LLY41_05730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LLY41_05735	COG1388	LysM domain
LLY41_05735	COG1388	LysM domain
LLY41_05740	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LLY41_05750	COG0525	valine-tRNA ligase activity
LLY41_05755	COG0285	dihydrofolate synthase activity
LLY41_05810	COG1459	type II secretion system
LLY41_05820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LLY41_05850	COG0424	maF-like protein
LLY41_05855	COG2003	Belongs to the UPF0758 family
LLY41_05865	COG1792	Involved in formation and maintenance of cell shape
LLY41_05875	COG0850	regulation of cytokinetic process
LLY41_05880	COG2894	cell division
LLY41_05885	COG0739	heme binding
LLY41_05890	COG1994	Peptidase M50
LLY41_05895	COG1530	ribonuclease E activity
LLY41_05900	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LLY41_05905	COG2868	ribosomal protein
LLY41_05910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LLY41_05915	COG3290	protein histidine kinase activity
LLY41_05920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LLY41_05925	COG4492	Belongs to the UPF0735 family
LLY41_05930	COG0077	Prephenate dehydratase
LLY41_05935	COG1827	regulation of RNA biosynthetic process
LLY41_05940	COG1104	cysteine desulfurase activity
LLY41_05955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LLY41_05960	COG1388	LysM domain
LLY41_05980	COG0582	viral genome integration into host DNA
LLY41_05990	COG2111	Na H antiporter
LLY41_05990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LLY41_05995	COG2111	Na H antiporter
LLY41_06000	COG1006	Multisubunit Na H antiporter MnhC subunit
LLY41_06010	COG1863	multisubunit Na H antiporter MnhE subunit
LLY41_06015	COG2212	antiporter activity
LLY41_06020	COG1320	monovalent cation:proton antiporter activity
LLY41_06025	COG0632	four-way junction helicase activity
LLY41_06030	COG2255	four-way junction helicase activity
LLY41_06040	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LLY41_06045	COG0343	queuine tRNA-ribosyltransferase activity
LLY41_06050	COG1862	Preprotein translocase
LLY41_06065	COG2323	membrane
LLY41_06070	COG2244	polysaccharide biosynthetic process
LLY41_06085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LLY41_06090	COG5416	Lipopolysaccharide assembly protein A domain
LLY41_06095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LLY41_06095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LLY41_06100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLY41_06110	COG1490	D-aminoacyl-tRNA deacylase activity
LLY41_06115	COG4991	sh3 domain protein
LLY41_06115	COG3103	Sh3 type 3 domain protein
LLY41_06115	COG0860	N-Acetylmuramoyl-L-alanine amidase
LLY41_06125	COG0124	histidyl-tRNA synthetase
LLY41_06130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LLY41_06140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LLY41_06150	COG1131	(ABC) transporter
LLY41_06155	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LLY41_06160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LLY41_06165	COG1959	2 iron, 2 sulfur cluster binding
LLY41_06170	COG1104	cysteine desulfurase activity
LLY41_06185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LLY41_06210	COG0628	permease
LLY41_06215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LLY41_06220	COG4472	Bacterial protein of unknown function (DUF965)
LLY41_06230	COG3906	Belongs to the UPF0473 family
LLY41_06235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LLY41_06240	COG4122	O-methyltransferase activity
LLY41_06245	COG0826	peptidase U32
LLY41_06250	COG0826	peptidase U32
LLY41_06255	COG0572	uridine kinase
LLY41_06260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LLY41_06265	COG0768	penicillin binding
LLY41_06280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LLY41_06315	COG1183	phosphatidylcholine synthase activity
LLY41_06330	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LLY41_06335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LLY41_06345	COG1534	Rna-binding protein
LLY41_06350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LLY41_06355	COG1713	HD superfamily hydrolase involved in NAD metabolism
LLY41_06360	COG0799	negative regulation of ribosome biogenesis
LLY41_06365	COG2226	methyltransferase
LLY41_06370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLY41_06375	COG1596	polysaccharide export
LLY41_06375	COG1555	photosystem II stabilization
LLY41_06380	COG2131	deaminase
LLY41_06385	COG0658	competence protein
LLY41_06385	COG2333	competence protein COMEC
LLY41_06395	COG1466	dna polymerase III delta subunit
LLY41_06400	COG0268	Binds directly to 16S ribosomal RNA
LLY41_06420	COG0481	GTPase activity
LLY41_06425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LLY41_06430	COG1420	regulation of RNA biosynthetic process
LLY41_06435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LLY41_06440	COG0443	Heat shock 70 kDa protein
LLY41_06445	COG0484	heat shock protein binding
LLY41_06450	COG2264	protein methyltransferase activity
LLY41_06455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LLY41_06460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LLY41_06465	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LLY41_06470	COG1283	sodium-dependent phosphate transmembrane transporter activity
LLY41_06480	COG1610	YqeY-like protein
LLY41_06485	COG1030	water channel activity
LLY41_06510	COG1702	phosphate starvation-inducible protein PhoH
LLY41_06520	COG1480	7TM receptor with intracellular HD hydrolase
LLY41_06530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LLY41_06535	COG0295	cytidine deaminase activity
LLY41_06540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LLY41_06550	COG1381	Involved in DNA repair and RecF pathway recombination
LLY41_06555	COG0752	glycyl-tRNA synthetase alpha subunit
LLY41_06560	COG0751	glycine-tRNA ligase activity
LLY41_06565	COG0517	IMP dehydrogenase activity
LLY41_06580	COG0358	DNA primase activity
LLY41_06585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LLY41_06595	COG1960	acyl-CoA dehydrogenase activity
LLY41_06600	COG2010	Cytochrome c
LLY41_06610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LLY41_06615	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LLY41_06625	COG0513	Belongs to the DEAD box helicase family
LLY41_06630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LLY41_06640	COG1121	(ABC) transporter
LLY41_06645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LLY41_06650	COG0735	belongs to the Fur family
LLY41_06655	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LLY41_06660	COG4709	membrane
LLY41_06675	COG5521	maltodextrose utilization protein MalA
LLY41_06680	COG1283	sodium-dependent phosphate transmembrane transporter activity
LLY41_06685	COG2839	Protein conserved in bacteria
LLY41_06695	COG0477	Major facilitator Superfamily
LLY41_06700	COG0768	penicillin binding
LLY41_06705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LLY41_06710	COG0573	inorganic phosphate transmembrane transporter activity
LLY41_06715	COG0581	inorganic phosphate transmembrane transporter activity
LLY41_06720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLY41_06725	COG0704	Plays a role in the regulation of phosphate uptake
LLY41_06760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LLY41_06780	COG0457	Tetratricopeptide repeat
LLY41_06780	COG0705	Rhomboid family
LLY41_06785	COG0697	spore germination
LLY41_06795	COG1940	carbohydrate kinase activity
LLY41_06810	COG0011	TIGRFAM Protein of
LLY41_06825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLY41_06845	COG1393	Belongs to the ArsC family
LLY41_06855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LLY41_06860	COG1459	type II secretion system
LLY41_06865	COG4537	Required for transformation and DNA binding
LLY41_06870	COG4970	Tfp pilus assembly protein FimT
LLY41_06905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LLY41_06910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LLY41_06920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LLY41_06925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLY41_06930	COG0095	Lipoate-protein ligase
LLY41_06935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLY41_06945	COG1752	Esterase of the alpha-beta hydrolase superfamily
LLY41_06960	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LLY41_06965	COG0006	proline dipeptidase activity
LLY41_06970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LLY41_06985	COG1785	Belongs to the alkaline phosphatase family
LLY41_06990	COG3854	ATPases associated with a variety of cellular activities
LLY41_07030	COG0511	ligase activity, forming carbon-carbon bonds
LLY41_07035	COG0439	Biotin carboxylase
LLY41_07040	COG1302	Protein conserved in bacteria
LLY41_07050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LLY41_07060	COG1722	exodeoxyribonuclease VII activity
LLY41_07075	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LLY41_07080	COG1438	arginine binding
LLY41_07090	COG0750	zinc metalloprotease
LLY41_07100	COG3093	addiction module antidote protein HigA
LLY41_07110	COG3829	transcription factor binding
LLY41_07110	COG3290	protein histidine kinase activity
LLY41_07115	COG0280	phosphate acetyltransferase
LLY41_07130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLY41_07135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LLY41_07140	COG0022	dehydrogenase e1 component
LLY41_07145	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLY41_07155	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LLY41_07155	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LLY41_07160	COG1703	isobutyryl-CoA mutase activity
LLY41_07170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLY41_07175	COG0765	amino acid transport
LLY41_07180	COG1126	abc transporter atp-binding protein
LLY41_07190	COG1376	ErfK ybiS ycfS ynhG family protein
LLY41_07200	COG0346	lactoylglutathione lyase activity
LLY41_07205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LLY41_07210	COG2195	Cleaves the N-terminal amino acid of tripeptides
LLY41_07220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLY41_07225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LLY41_07230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LLY41_07245	COG0733	neurotransmitter:sodium symporter activity
LLY41_07250	COG1902	pentaerythritol trinitrate reductase activity
LLY41_07255	COG1215	transferase activity, transferring glycosyl groups
LLY41_07260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLY41_07265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLY41_07270	COG0300	oxidoreductase activity
LLY41_07290	COG4918	Iron-sulphur cluster biosynthesis
LLY41_07305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LLY41_07315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LLY41_07320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LLY41_07335	COG0667	Aldo Keto reductase
LLY41_07350	COG1379	DNA repair
LLY41_07360	COG1300	Membrane
LLY41_07365	COG0735	belongs to the Fur family
LLY41_07375	COG4974	Belongs to the 'phage' integrase family
LLY41_07380	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LLY41_07405	COG2172	sigma factor antagonist activity
LLY41_07430	COG0697	spore germination
LLY41_07440	COG4086	secreted protein
LLY41_07450	COG1547	Domain of unknown function (DUF309)
LLY41_07465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LLY41_07480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LLY41_07485	COG1686	Belongs to the peptidase S11 family
LLY41_07490	COG2715	membrane protein required for spore maturation
LLY41_07500	COG1187	pseudouridine synthase activity
LLY41_07505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLY41_07510	COG1333	cytochrome c biogenesis protein
LLY41_07515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LLY41_07520	COG0745	RESPONSE REGULATOR receiver
LLY41_07525	COG5002	protein histidine kinase activity
LLY41_07530	COG1595	DNA-templated transcription, initiation
LLY41_07540	COG0739	heme binding
LLY41_07540	COG0741	lytic transglycosylase activity
LLY41_07540	COG1196	nuclear chromosome segregation
LLY41_07545	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LLY41_07550	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LLY41_07560	COG4955	Helix-turn-helix domain
LLY41_07565	COG0514	ATP-dependent DNA helicase (RecQ)
LLY41_07570	COG1266	CAAX protease self-immunity
LLY41_07585	COG3546	catalase activity
LLY41_07610	COG1408	metallophosphoesterase
LLY41_07620	COG4862	establishment of competence for transformation
LLY41_07625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LLY41_07630	COG0492	ferredoxin-NADP+ reductase activity
LLY41_07635	COG0252	asparaginase activity
LLY41_07665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LLY41_07670	COG0204	Acyl-transferase
LLY41_07675	COG0539	negative regulation of cytoplasmic translation
LLY41_07705	COG1160	GTP binding
LLY41_07710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LLY41_07725	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LLY41_07730	COG0776	regulation of translation
LLY41_07735	COG0302	gtp cyclohydrolase
LLY41_07750	COG2226	methyltransferase
LLY41_07760	COG0105	UTP biosynthetic process
LLY41_07765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LLY41_07770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LLY41_07775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LLY41_07780	COG4401	Chorismate mutase type I
LLY41_07785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LLY41_07790	COG0287	Prephenate dehydrogenase
LLY41_07805	COG0457	Tetratricopeptide repeat
LLY41_07825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LLY41_07835	COG4347	Protein of unknown function (DUF1405)
LLY41_07845	COG2738	Putative neutral zinc metallopeptidase
LLY41_07850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLY41_07855	COG1694	Mazg nucleotide pyrophosphohydrolase
LLY41_07870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LLY41_07875	COG0438	transferase activity, transferring glycosyl groups
LLY41_07890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LLY41_07895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LLY41_07900	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LLY41_07905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LLY41_07905	COG1199	ATP-dependent helicase activity
LLY41_07935	COG3935	DnaD domain protein
LLY41_07940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LLY41_07955	COG4499	WXG100 protein secretion system (Wss), protein YukC
LLY41_07955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLY41_07960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLY41_07960	COG4499	WXG100 protein secretion system (Wss), protein YukC
LLY41_08000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLY41_08005	COG0071	Belongs to the small heat shock protein (HSP20) family
LLY41_08020	COG0601	transmembrane transport
LLY41_08025	COG1111	helicase
LLY41_08025	COG1205	dead DEAH box helicase
LLY41_08030	COG3359	exonuclease
LLY41_08045	COG4474	Belongs to the UPF0398 family
LLY41_08050	COG3599	regulation of cell shape
LLY41_08060	COG0116	Belongs to the methyltransferase superfamily
LLY41_08070	COG1199	ATP-dependent helicase activity
LLY41_08075	COG2151	metal-sulfur cluster biosynthetic enzyme
LLY41_08105	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LLY41_08115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LLY41_08120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LLY41_08130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLY41_08135	COG2233	PERMEase
LLY41_08145	COG3424	synthase
LLY41_08150	COG1755	Isoprenylcysteine carboxyl methyltransferase
LLY41_08155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LLY41_08180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLY41_08205	COG0328	RNA-DNA hybrid ribonuclease activity
LLY41_08210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LLY41_08215	COG0328	RNA-DNA hybrid ribonuclease activity
LLY41_08225	COG1278	Cold shock
LLY41_08245	COG1321	iron dependent repressor
LLY41_08295	COG1418	mRNA catabolic process
LLY41_08300	COG0488	(ABC) transporter
LLY41_08305	COG1413	lyase activity
LLY41_08310	COG0129	dihydroxy-acid dehydratase activity
LLY41_08320	COG2136	Putative SAM-dependent methyltransferase
LLY41_08320	COG2521	methyltransferase
LLY41_08325	COG0436	Aminotransferase
LLY41_08335	COG2310	stress, protein
LLY41_08340	COG0861	Integral membrane protein TerC family
LLY41_08375	COG3853	Toxic anion resistance protein (TelA)
LLY41_08380	COG2310	stress, protein
LLY41_08395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LLY41_08400	COG0204	Acyl-transferase
LLY41_08410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LLY41_08415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LLY41_08420	COG0805	protein transport
LLY41_08430	COG1307	EDD domain protein, DegV family
LLY41_08440	COG1999	signal sequence binding
LLY41_08445	COG2755	lipolytic protein G-D-S-L family
LLY41_08465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLY41_08470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLY41_08475	COG2190	(PTS) system
LLY41_08495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LLY41_08500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LLY41_08505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LLY41_08510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LLY41_08515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LLY41_08525	COG0456	acetyltransferase
LLY41_08530	COG3829	transcription factor binding
LLY41_08535	COG1509	lysine 2,3-aminomutase activity
LLY41_08545	COG4479	Belongs to the UPF0346 family
LLY41_08570	COG0584	glycerophosphoryl diester phosphodiesterase
LLY41_08590	COG1876	peptidase activity
LLY41_08605	COG3409	Peptidoglycan-binding domain 1 protein
LLY41_08605	COG0793	Belongs to the peptidase S41A family
LLY41_08610	COG1316	TRANSCRIPTIONal
LLY41_08615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LLY41_08625	COG0523	cobalamin synthesis protein
LLY41_08650	COG0745	RESPONSE REGULATOR receiver
LLY41_08655	COG5002	protein histidine kinase activity
LLY41_08665	COG2340	Cysteine-rich secretory protein family
LLY41_08670	COG0454	-acetyltransferase
LLY41_08685	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_08690	COG0534	Mate efflux family protein
LLY41_08710	COG0586	Pfam SNARE associated Golgi protein
LLY41_08735	COG1131	(ABC) transporter
LLY41_08740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LLY41_08745	COG4667	esterase of the alpha-beta hydrolase superfamily
LLY41_08755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLY41_08760	COG2217	Heavy metal translocating P-type atpase
LLY41_08765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LLY41_08765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LLY41_08770	COG0307	riboflavin synthase, alpha
LLY41_08775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLY41_08775	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLY41_08780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LLY41_08790	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LLY41_08795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LLY41_08805	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LLY41_08810	COG0671	phosphoesterase, PA-phosphatase related
LLY41_08815	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LLY41_08820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LLY41_08830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LLY41_08845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LLY41_08855	COG0513	Belongs to the DEAD box helicase family
LLY41_08870	COG1214	PFAM Peptidase M22, glycoprotease
LLY41_08870	COG0456	acetyltransferase
LLY41_08910	COG1280	lysine exporter protein (LysE YggA)
LLY41_08925	COG1937	Protein conserved in bacteria
LLY41_08930	COG2608	mercury ion transmembrane transporter activity
LLY41_08935	COG2217	Heavy metal translocating P-type atpase
LLY41_08940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLY41_08945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLY41_08950	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LLY41_08955	COG1268	BioY protein
LLY41_08970	COG1105	Belongs to the carbohydrate kinase PfkB family
LLY41_08975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLY41_08975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLY41_08975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLY41_09000	COG0596	Alpha beta hydrolase
LLY41_09005	COG2814	Major facilitator Superfamily
LLY41_09010	COG2258	MOSC domain
LLY41_09020	COG0512	Glutamine amidotransferase of anthranilate synthase
LLY41_09020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LLY41_09025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LLY41_09030	COG0134	indole-3-glycerol-phosphate synthase activity
LLY41_09055	COG2011	ABC-type metal ion transport system permease component
LLY41_09065	COG1704	LemA family
LLY41_09075	COG2226	methyltransferase
LLY41_09085	COG2135	peptidase activity
LLY41_09095	COG2318	DinB family
LLY41_09135	COG0243	molybdopterin cofactor binding
LLY41_09165	COG2223	nitrite transmembrane transporter activity
LLY41_09175	COG2197	response regulator
LLY41_09185	COG4585	Histidine kinase
LLY41_09195	COG1695	Transcriptional regulator
LLY41_09200	COG2966	Psort location CytoplasmicMembrane, score
LLY41_09205	COG3610	response to peptide
LLY41_09210	COG1132	(ABC) transporter
LLY41_09215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLY41_09220	COG1472	Belongs to the glycosyl hydrolase 3 family
LLY41_09240	COG3153	acetyltransferase
LLY41_09240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LLY41_09260	COG3226	Transcriptional regulator
LLY41_09265	COG3383	formate dehydrogenase (NAD+) activity
LLY41_09270	COG2427	Protein of unknown function (DUF1641)
LLY41_09285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LLY41_09290	COG5609	conserved protein (DUF2294)
LLY41_09295	COG0791	NLP P60 protein
LLY41_09295	COG3883	PFAM NLP P60 protein
LLY41_09300	COG2186	Transcriptional regulator
LLY41_09305	COG0277	FAD linked oxidase domain protein
LLY41_09310	COG0247	lactate metabolic process
LLY41_09315	COG0277	FAD linked oxidase domain protein
LLY41_09330	COG1414	Transcriptional regulator
LLY41_09335	COG1620	l-lactate permease
LLY41_09340	COG1725	Transcriptional regulator
LLY41_09345	COG1131	(ABC) transporter
LLY41_09355	COG1595	DNA-templated transcription, initiation
LLY41_09370	COG0183	Belongs to the thiolase family
LLY41_09380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LLY41_09390	COG1183	phosphatidylcholine synthase activity
LLY41_09395	COG0322	excinuclease ABC activity
LLY41_09415	COG1022	Amp-dependent synthetase and ligase
LLY41_09430	COG0683	leucine binding
LLY41_09455	COG3832	glyoxalase III activity
LLY41_09475	COG0745	RESPONSE REGULATOR receiver
LLY41_09480	COG5002	protein histidine kinase activity
LLY41_09505	COG0456	acetyltransferase
LLY41_09510	COG0778	Nitroreductase
LLY41_09540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LLY41_09560	COG2002	toxin-antitoxin pair type II binding
LLY41_09585	COG0598	Magnesium transport protein CorA
LLY41_09595	COG4149	molybdate abc transporter
LLY41_09605	COG1846	Transcriptional regulator
LLY41_09610	COG0346	lactoylglutathione lyase activity
LLY41_09615	COG0400	carboxylic ester hydrolase activity
LLY41_09620	COG0655	NAD(P)H dehydrogenase (quinone) activity
LLY41_09625	COG1741	Belongs to the pirin family
LLY41_09640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLY41_09660	COG2801	Transposase and inactivated derivatives
LLY41_09670	COG0860	N-Acetylmuramoyl-L-alanine amidase
LLY41_09705	COG2801	Transposase and inactivated derivatives
LLY41_09710	COG0243	molybdopterin cofactor binding
LLY41_09715	COG2197	response regulator
LLY41_09735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LLY41_09750	COG0583	DNA-binding transcription factor activity
LLY41_09755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LLY41_09795	COG0456	acetyltransferase
LLY41_09805	COG1051	belongs to the nudix hydrolase family
LLY41_09830	COG1054	Belongs to the UPF0176 family
LLY41_09835	COG1280	lysine exporter protein (LysE YggA)
LLY41_09870	COG0842	Transport permease protein
LLY41_09875	COG1131	(ABC) transporter
LLY41_09900	COG5000	phosphorelay sensor kinase activity
LLY41_09900	COG5002	protein histidine kinase activity
LLY41_09905	COG1595	DNA-templated transcription, initiation
LLY41_09915	COG1140	nitrate reductase beta subunit
LLY41_09920	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LLY41_09925	COG2181	nitrate reductase activity
LLY41_09935	COG2223	nitrite transmembrane transporter activity
LLY41_09965	COG0586	Pfam SNARE associated Golgi protein
LLY41_09970	COG1253	flavin adenine dinucleotide binding
LLY41_09975	COG0789	Transcriptional regulator
LLY41_09980	COG1301	dicarboxylic acid transport
LLY41_09995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLY41_10000	COG2356	endonuclease I
LLY41_10010	COG0569	domain protein
LLY41_10015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LLY41_10055	COG0789	Transcriptional regulator
LLY41_10065	COG0697	spore germination
LLY41_10075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LLY41_10085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LLY41_10095	COG1802	Transcriptional regulator
LLY41_10100	COG1114	Component of the transport system for branched-chain amino acids
LLY41_10105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LLY41_10110	COG1733	regulation of RNA biosynthetic process
LLY41_10115	COG2259	Doxx family
LLY41_10120	COG2514	catechol 2,3-dioxygenase activity
LLY41_10135	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LLY41_10145	COG1742	UPF0060 membrane protein
LLY41_10150	COG2814	Major facilitator Superfamily
LLY41_10155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLY41_10175	COG1609	Transcriptional regulator
LLY41_10200	COG2304	oxidoreductase activity
LLY41_10205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLY41_10235	COG1231	oxidoreductase activity
LLY41_10245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLY41_10260	COG0697	spore germination
LLY41_10265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LLY41_10270	COG2807	transmembrane transport
LLY41_10280	COG0492	ferredoxin-NADP+ reductase activity
LLY41_10295	COG0640	Transcriptional regulator
LLY41_10300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LLY41_10305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLY41_10320	COG5002	protein histidine kinase activity
LLY41_10320	COG3850	Histidine kinase
LLY41_10330	COG2409	Drug exporters of the RND superfamily
LLY41_10335	COG2323	membrane
LLY41_10340	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_10365	COG1193	negative regulation of DNA recombination
LLY41_10370	COG1757	Na H antiporter
LLY41_10395	COG1657	PFAM Prenyltransferase squalene oxidase
LLY41_10410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLY41_10425	COG1301	dicarboxylic acid transport
LLY41_10440	COG0322	excinuclease ABC activity
LLY41_10445	COG1737	Transcriptional regulator
LLY41_10455	COG1175	transmembrane transport
LLY41_10460	COG0395	ABC-type sugar transport system, permease component
LLY41_10470	COG2971	BadF BadG BcrA BcrD
LLY41_10505	COG3829	transcription factor binding
LLY41_10535	COG1024	Enoyl-CoA hydratase
LLY41_10545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LLY41_10550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LLY41_10560	COG1012	belongs to the aldehyde dehydrogenase family
LLY41_10570	COG0247	lactate metabolic process
LLY41_10580	COG1671	Belongs to the UPF0178 family
LLY41_10585	COG1401	restriction endodeoxyribonuclease activity
LLY41_10595	COG1061	Type III restriction enzyme res subunit
LLY41_10600	COG0494	nUDIX hydrolase
LLY41_10625	COG1414	Transcriptional regulator
LLY41_10630	COG0028	Belongs to the TPP enzyme family
LLY41_10635	COG1012	belongs to the aldehyde dehydrogenase family
LLY41_10640	COG0129	dihydroxy-acid dehydratase activity
LLY41_10650	COG1129	ABC transporter
LLY41_10655	COG1172	Belongs to the binding-protein-dependent transport system permease family
LLY41_10665	COG0788	formyltetrahydrofolate deformylase activity
LLY41_10700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLY41_10710	COG0697	spore germination
LLY41_10735	COG4412	M6 family metalloprotease domain protein
LLY41_10735	COG1404	Belongs to the peptidase S8 family
LLY41_10780	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LLY41_10815	COG0109	protoheme IX farnesyltransferase activity
LLY41_10835	COG2146	nitrite reductase [NAD(P)H] activity
LLY41_10840	COG1476	TRANSCRIPTIONal
LLY41_10855	COG0789	Transcriptional regulator
LLY41_10915	COG3655	Transcriptional regulator
LLY41_10920	COG3739	integral membrane protein
LLY41_10945	COG3559	Exporter of polyketide antibiotics
LLY41_10955	COG1473	amidohydrolase
LLY41_10965	COG4948	Mandelate Racemase Muconate Lactonizing
LLY41_10970	COG3949	Membrane
LLY41_10975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LLY41_10980	COG2602	Beta-lactamase
LLY41_11015	COG0500	methyltransferase
LLY41_11055	COG0346	lactoylglutathione lyase activity
LLY41_11060	COG1104	cysteine desulfurase activity
LLY41_11080	COG0662	Cupin 2, conserved barrel domain protein
LLY41_11095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLY41_11095	COG2213	PTS system mannitol-specific
LLY41_11100	COG3711	transcriptional antiterminator
LLY41_11105	COG0246	Mannitol dehydrogenase
LLY41_11145	COG0534	Mate efflux family protein
LLY41_11155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LLY41_11160	COG0747	negative chemotaxis
LLY41_11165	COG0601	transmembrane transport
LLY41_11170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLY41_11175	COG0444	Belongs to the ABC transporter superfamily
LLY41_11195	COG2608	mercury ion transmembrane transporter activity
LLY41_11200	COG2217	Heavy metal translocating P-type atpase
LLY41_11210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LLY41_11220	COG1940	carbohydrate kinase activity
LLY41_11225	COG2115	Belongs to the xylose isomerase family
LLY41_11230	COG1070	Carbohydrate kinase
LLY41_11240	COG2814	Major facilitator Superfamily
LLY41_11240	COG0477	Major facilitator Superfamily
LLY41_11250	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLY41_11255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LLY41_11260	COG1121	(ABC) transporter
LLY41_11265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LLY41_11275	COG1368	sulfuric ester hydrolase activity
LLY41_11295	COG1917	Cupin 2, conserved barrel domain protein
LLY41_11295	COG2207	Transcriptional regulator
LLY41_11300	COG0697	spore germination
LLY41_11305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LLY41_11330	COG0456	acetyltransferase
LLY41_11345	COG0183	Belongs to the thiolase family
LLY41_11350	COG0318	PFAM AMP-dependent synthetase and ligase
LLY41_11355	COG1268	BioY protein
LLY41_11375	COG0385	Bile acid
LLY41_11380	COG1098	S1 RNA binding domain
LLY41_11400	COG5002	protein histidine kinase activity
LLY41_11435	COG3383	formate dehydrogenase (NAD+) activity
LLY41_11440	COG1388	LysM domain
LLY41_11440	COG1705	Flagellar rod assembly protein muramidase FlgJ
LLY41_11450	COG0726	polysaccharide deacetylase
LLY41_11460	COG0500	methyltransferase
LLY41_11460	COG3615	Tellurite resistance protein tehB
LLY41_11465	COG2188	Transcriptional regulator
LLY41_11470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLY41_11475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LLY41_11480	COG1447	Phosphotransferase system cellobiose-specific component IIA
LLY41_11485	COG1486	melibiose metabolic process
LLY41_11490	COG3394	polysaccharide catabolic process
LLY41_11495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLY41_11495	COG1263	PTS System
LLY41_11500	COG0363	glucosamine-6-phosphate deaminase activity
LLY41_11505	COG4821	SIS domain
LLY41_11515	COG0577	efflux transmembrane transporter activity
LLY41_11520	COG1136	(ABC) transporter
LLY41_11525	COG0642	Histidine kinase
LLY41_11530	COG0745	RESPONSE REGULATOR receiver
LLY41_11575	COG2814	Major facilitator Superfamily
LLY41_11580	COG1846	Transcriptional regulator
LLY41_11585	COG2357	RelA SpoT domain protein
LLY41_11595	COG1309	transcriptional regulator
LLY41_11600	COG2223	nitrite transmembrane transporter activity
LLY41_11615	COG0346	lactoylglutathione lyase activity
LLY41_11635	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_11640	COG0318	PFAM AMP-dependent synthetase and ligase
LLY41_11645	COG1309	transcriptional regulator
LLY41_11650	COG1250	3-hydroxyacyl-CoA dehydrogenase
LLY41_11670	COG1960	acyl-CoA dehydrogenase activity
LLY41_11680	COG2226	methyltransferase
LLY41_11685	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_11690	COG2814	Major facilitator Superfamily
LLY41_11705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LLY41_11715	COG3290	protein histidine kinase activity
LLY41_11715	COG3829	transcription factor binding
LLY41_11720	COG0277	FAD linked oxidase domain protein
LLY41_11725	COG0247	lactate metabolic process
LLY41_11735	COG1802	Transcriptional regulator
LLY41_11745	COG1024	Enoyl-CoA hydratase
LLY41_11770	COG0673	inositol 2-dehydrogenase activity
LLY41_11780	COG0175	sulfate reduction
LLY41_11785	COG0306	phosphate transporter
LLY41_11790	COG2046	Belongs to the sulfate adenylyltransferase family
LLY41_11795	COG0529	Catalyzes the synthesis of activated sulfate
LLY41_11815	COG3835	regulator
LLY41_11820	COG2610	gluconate transmembrane transporter activity
LLY41_11825	COG1929	Belongs to the glycerate kinase type-1 family
LLY41_11840	COG2814	Major facilitator Superfamily
LLY41_11845	COG0840	transmembrane signaling receptor activity
LLY41_11860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LLY41_11865	COG1012	belongs to the aldehyde dehydrogenase family
LLY41_11870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LLY41_11875	COG0613	PHP domain protein
LLY41_11880	COG2046	Belongs to the sulfate adenylyltransferase family
LLY41_11885	COG0529	Catalyzes the synthesis of activated sulfate
LLY41_11910	COG0471	metal ion transport
LLY41_11910	COG3273	potassium ion transport
LLY41_11915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LLY41_11920	COG1088	dTDP-glucose 4,6-dehydratase activity
LLY41_11925	COG1091	dTDP-4-dehydrorhamnose reductase activity
LLY41_11930	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LLY41_11950	COG0463	Glycosyl transferase, family 2
LLY41_11955	COG4641	Protein conserved in bacteria
LLY41_12020	COG1482	cell wall glycoprotein biosynthetic process
LLY41_12030	COG1272	protein, Hemolysin III
LLY41_12040	COG1968	undecaprenyl-diphosphatase activity
LLY41_12065	COG1131	(ABC) transporter
LLY41_12075	COG4536	flavin adenine dinucleotide binding
LLY41_12085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LLY41_12095	COG3773	Cell wall hydrolase
LLY41_12105	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LLY41_12120	COG4990	cell redox homeostasis
LLY41_12135	COG0697	spore germination
LLY41_12145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LLY41_12155	COG0561	phosphatase activity
LLY41_12160	COG1764	response to oxidative stress
LLY41_12165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LLY41_12170	COG0351	phosphomethylpyrimidine kinase
LLY41_12180	COG0708	Exodeoxyribonuclease III
LLY41_12190	COG2076	Multidrug Resistance protein
LLY41_12195	COG2076	Multidrug Resistance protein
LLY41_12215	COG0628	permease
LLY41_12225	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_12230	COG0737	Belongs to the 5'-nucleotidase family
LLY41_12235	COG4336	lyase activity
LLY41_12240	COG1914	H( )-stimulated, divalent metal cation uptake system
LLY41_12245	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LLY41_12250	COG1984	allophanate hydrolase subunit 2
LLY41_12255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LLY41_12270	COG0720	synthase
LLY41_12280	COG3842	ATPase activity
LLY41_12285	COG1176	ABC-type spermidine putrescine transport system, permease component I
LLY41_12300	COG2861	carbohydrate metabolic process
LLY41_12310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLY41_12330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LLY41_12335	COG1845	cytochrome c oxidase, subunit III
LLY41_12340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LLY41_12350	COG0697	spore germination
LLY41_12375	COG2340	Cysteine-rich secretory protein family
LLY41_12410	COG0656	L-ascorbic acid biosynthetic process
LLY41_12445	COG0546	phosphoglycolate phosphatase activity
LLY41_12455	COG0646	methionine synthase
LLY41_12455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LLY41_12460	COG0626	cystathionine gamma-synthase activity
LLY41_12465	COG0626	cystathionine gamma-synthase activity
LLY41_12475	COG0567	Dehydrogenase, E1 component
LLY41_12480	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLY41_12495	COG0318	PFAM AMP-dependent synthetase and ligase
LLY41_12505	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LLY41_12505	COG2105	PFAM AIG2 family protein
LLY41_12540	COG0392	lysyltransferase activity
LLY41_12540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LLY41_12550	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LLY41_12565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LLY41_12575	COG2340	Cysteine-rich secretory protein family
LLY41_12585	COG1609	Transcriptional regulator
LLY41_12585	COG2207	Transcriptional regulator
LLY41_12590	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LLY41_12595	COG1228	amidohydrolase
LLY41_12600	COG0010	Belongs to the arginase family
LLY41_12605	COG3314	Sporulation integral membrane protein YlbJ
LLY41_12610	COG2404	hydrolase activity, acting on ester bonds
LLY41_12615	COG1686	Belongs to the peptidase S11 family
LLY41_12630	COG0488	(ABC) transporter
LLY41_12635	COG2030	dehydratase
LLY41_12650	COG1999	signal sequence binding
LLY41_12655	COG1012	belongs to the aldehyde dehydrogenase family
LLY41_12660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LLY41_12675	COG3361	conserved protein (COG2071)
LLY41_12695	COG1164	Oligoendopeptidase f
LLY41_12705	COG5002	protein histidine kinase activity
LLY41_12710	COG1388	LysM domain
LLY41_12710	COG3584	3D domain protein
LLY41_12725	COG4989	oxidoreductase activity
LLY41_12735	COG2310	stress, protein
LLY41_12740	COG2310	stress, protein
LLY41_12765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLY41_12775	COG1418	mRNA catabolic process
LLY41_12785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LLY41_12790	COG3663	DNA glycosylase
LLY41_12795	COG1404	Belongs to the peptidase S8 family
LLY41_12805	COG3695	enzyme binding
LLY41_12815	COG2027	D-alanyl-D-alanine carboxypeptidase
LLY41_12820	COG2353	YceI-like domain
LLY41_12825	COG0514	ATP-dependent DNA helicase (RecQ)
LLY41_12855	COG3239	Fatty acid desaturase
LLY41_12860	COG4585	Histidine kinase
LLY41_12875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LLY41_12885	COG3621	Patatin-like phospholipase
LLY41_12905	COG1164	Oligoendopeptidase f
LLY41_12930	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LLY41_12945	COG0326	Molecular chaperone. Has ATPase activity
LLY41_12960	COG2323	membrane
LLY41_13005	COG1115	amino acid carrier protein
LLY41_13010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LLY41_13015	COG0187	DNA topoisomerase II activity
LLY41_13020	COG1832	CoA-binding protein
LLY41_13030	COG0402	S-adenosylhomocysteine deaminase activity
LLY41_13035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LLY41_13040	COG3665	Urea carboxylase-associated protein
LLY41_13045	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LLY41_13050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LLY41_13055	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
LLY41_13090	COG0163	prenyltransferase activity
LLY41_13095	COG1335	isochorismatase
LLY41_13120	COG0746	molybdenum cofactor guanylyltransferase activity
LLY41_13130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LLY41_13145	COG2252	PERMEase
LLY41_13160	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LLY41_13170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LLY41_13175	COG3852	Histidine kinase
LLY41_13180	COG2843	Capsule synthesis protein
LLY41_13190	COG4841	protein insertion into membrane
LLY41_13200	COG0824	Thioesterase
LLY41_13205	COG0464	growth
LLY41_13225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLY41_13235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LLY41_13275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LLY41_13290	COG0753	catalase activity
LLY41_13295	COG0488	(ABC) transporter
LLY41_13300	COG1307	EDD domain protein, DegV family
LLY41_13310	COG0179	Fumarylacetoacetate (FAA) hydrolase
LLY41_13315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LLY41_13320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LLY41_13325	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LLY41_13340	COG0022	dehydrogenase e1 component
LLY41_13360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LLY41_13365	COG4120	Belongs to the binding-protein-dependent transport system permease family
LLY41_13380	COG3327	negative regulation of DNA-templated transcription, initiation
LLY41_13385	COG0183	Belongs to the thiolase family
LLY41_13390	COG1250	3-hydroxyacyl-CoA dehydrogenase
LLY41_13395	COG1024	Enoyl-CoA hydratase
LLY41_13400	COG1024	Enoyl-CoA hydratase
LLY41_13425	COG3396	Phenylacetate-CoA oxygenase
LLY41_13430	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LLY41_13445	COG3764	Sortase (surface protein transpeptidase)
LLY41_13455	COG0217	transcriptional regulatory protein
LLY41_13470	COG1525	nuclease
LLY41_13475	COG1760	l-serine dehydratase
LLY41_13480	COG1760	l-serine dehydratase
LLY41_13495	COG5002	protein histidine kinase activity
LLY41_13500	COG0745	RESPONSE REGULATOR receiver
LLY41_13510	COG1388	LysM domain
LLY41_13520	COG1368	sulfuric ester hydrolase activity
LLY41_13525	COG2364	Membrane
LLY41_13530	COG1199	ATP-dependent helicase activity
LLY41_13530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LLY41_13545	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LLY41_13545	COG3264	Mechanosensitive ion channel
LLY41_13550	COG0628	permease
LLY41_13555	COG1363	Peptidase, m42
LLY41_13595	COG0791	NLP P60 protein
LLY41_13595	COG1388	LysM domain
LLY41_13625	COG0137	argininosuccinate synthase activity
LLY41_13630	COG0419	ATPase involved in DNA repair
LLY41_13670	COG0840	transmembrane signaling receptor activity
LLY41_13675	COG2720	vancomycin resistance protein
LLY41_13685	COG2814	Major facilitator Superfamily
LLY41_13700	COG0069	glutamate synthase activity
LLY41_13710	COG0366	Alpha amylase catalytic
LLY41_13715	COG0366	Alpha amylase catalytic
LLY41_13720	COG0395	ABC-type sugar transport system, permease component
LLY41_13725	COG1175	transmembrane transport
LLY41_13730	COG1653	transport
LLY41_13740	COG1587	Uroporphyrinogen-III synthase
LLY41_13745	COG1368	sulfuric ester hydrolase activity
LLY41_13750	COG1942	4-Oxalocrotonate Tautomerase
LLY41_13755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LLY41_13765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LLY41_13770	COG1113	amino acid transport
LLY41_13790	COG3971	2-oxopent-4-enoate hydratase activity
LLY41_13800	COG0251	oxidation-reduction process
LLY41_13815	COG0431	NADPH-dependent FMN reductase
LLY41_13820	COG0196	riboflavin kinase activity
LLY41_13825	COG2368	4-hydroxyphenylacetate
LLY41_13840	COG0741	lytic transglycosylase activity
LLY41_13850	COG3622	Belongs to the hyi family
LLY41_13855	COG2304	oxidoreductase activity
LLY41_13875	COG2059	Chromate
LLY41_13880	COG2059	Chromate
LLY41_13925	COG3069	C4-dicarboxylate transmembrane transporter activity
LLY41_13930	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LLY41_13945	COG0697	spore germination
LLY41_13955	COG1404	Belongs to the peptidase S8 family
LLY41_13960	COG0657	acetylesterase activity
LLY41_13965	COG2072	flavoprotein involved in K transport
LLY41_13970	COG2197	response regulator
LLY41_13975	COG3681	Belongs to the UPF0597 family
LLY41_13985	COG0395	ABC-type sugar transport system, permease component
LLY41_13990	COG1175	transmembrane transport
LLY41_14000	COG1472	Belongs to the glycosyl hydrolase 3 family
LLY41_14005	COG3459	Glycosyltransferase 36 associated
LLY41_14015	COG1609	Transcriptional regulator
LLY41_14025	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LLY41_14035	COG0697	spore germination
LLY41_14040	COG1174	glycine betaine transport
LLY41_14045	COG0517	IMP dehydrogenase activity
LLY41_14045	COG1125	glycine betaine transport
LLY41_14055	COG0281	malic enzyme
LLY41_14060	COG0583	DNA-binding transcription factor activity
LLY41_14070	COG0753	catalase activity
LLY41_14075	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_14085	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LLY41_14140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LLY41_14150	COG4166	transmembrane transport
LLY41_14155	COG4608	Belongs to the ABC transporter superfamily
LLY41_14160	COG0444	Belongs to the ABC transporter superfamily
LLY41_14165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLY41_14170	COG0601	transmembrane transport
LLY41_14200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LLY41_14210	COG4122	O-methyltransferase activity
LLY41_14235	COG3773	Cell wall hydrolase
LLY41_14240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLY41_14250	COG3201	nicotinamide mononucleotide transporter
LLY41_14260	COG0385	Bile acid
LLY41_14265	COG0277	FAD linked oxidase domain protein
LLY41_14270	COG2186	Transcriptional regulator
LLY41_14280	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_14295	COG4807	Protein conserved in bacteria
LLY41_14310	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LLY41_14315	COG0732	type I restriction modification DNA specificity domain
LLY41_14320	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LLY41_14390	COG4974	Belongs to the 'phage' integrase family
LLY41_14410	COG4846	Membrane protein involved in cytochrome C biogenesis
LLY41_14415	COG2201	protein-glutamate methylesterase activity
LLY41_14420	COG0785	Cytochrome C biogenesis protein
LLY41_14430	COG1132	(ABC) transporter
LLY41_14435	COG1132	(ABC) transporter
LLY41_14445	COG3763	UPF0154 protein
LLY41_14460	COG4224	UPF0291 protein
LLY41_14465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LLY41_14475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LLY41_14485	COG0174	glutamine synthetase
LLY41_14490	COG0789	Transcriptional regulator
LLY41_14495	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LLY41_14500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LLY41_14505	COG2860	membrane
LLY41_14515	COG0464	growth
LLY41_14520	COG1923	regulation of RNA biosynthetic process
LLY41_14525	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LLY41_14530	COG1077	Cell shape determining protein MreB Mrl
LLY41_14535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LLY41_14540	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LLY41_14550	COG0346	lactoylglutathione lyase activity
LLY41_14575	COG4550	Control of competence regulator ComK, YlbF/YmcA
LLY41_14580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LLY41_14585	COG1013	pyruvate-flavodoxin oxidoreductase activity
LLY41_14590	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LLY41_14590	COG0674	pyruvate-flavodoxin oxidoreductase activity
LLY41_14600	COG2359	stage V sporulation protein S
LLY41_14605	COG1692	metallophosphoesterase
LLY41_14610	COG1418	mRNA catabolic process
LLY41_14615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LLY41_14620	COG1546	Belongs to the CinA family
LLY41_14620	COG1058	Belongs to the CinA family
LLY41_14625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LLY41_14630	COG1426	Protein conserved in bacteria
LLY41_14645	COG0300	oxidoreductase activity
LLY41_14655	COG0612	Peptidase, M16
LLY41_14660	COG1079	Belongs to the binding-protein-dependent transport system permease family
LLY41_14665	COG4603	Belongs to the binding-protein-dependent transport system permease family
LLY41_14670	COG3845	ABC transporter
LLY41_14675	COG1744	ABC transporter substrate-binding protein PnrA-like
LLY41_14680	COG2188	Transcriptional regulator
LLY41_14685	COG1674	ftsk spoiiie
LLY41_14685	COG4980	gas vesicle protein
LLY41_14695	COG0740	serine-type endopeptidase activity
LLY41_14710	COG0527	aspartate kinase activity
LLY41_14715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LLY41_14720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LLY41_14725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLY41_14730	COG1873	PFAM PRC-barrel domain
LLY41_14735	COG0612	Peptidase, M16
LLY41_14740	COG0726	polysaccharide deacetylase
LLY41_14750	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LLY41_14755	COG0196	riboflavin kinase activity
LLY41_14760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LLY41_14770	COG1550	Protein conserved in bacteria
LLY41_14780	COG1358	cellular component organization or biogenesis
LLY41_14785	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LLY41_14790	COG0195	Participates in both transcription termination and antitermination
LLY41_14795	COG0779	Required for maturation of 30S ribosomal subunits
LLY41_14800	COG2176	DNA-directed DNA polymerase activity
LLY41_14805	COG0750	zinc metalloprotease
LLY41_14815	COG4589	Belongs to the CDS family
LLY41_14830	COG0528	UMP kinase activity
LLY41_14855	COG1191	sigma factor activity
LLY41_14860	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LLY41_14865	COG1776	CheC inhibitor of MCP methylation
LLY41_14870	COG0835	chemotaxis
LLY41_14875	COG0643	Histidine kinase
LLY41_14875	COG2198	Histidine kinase
LLY41_14880	COG2201	protein-glutamate methylesterase activity
LLY41_14885	COG0455	bacterial-type flagellum organization
LLY41_14890	COG1419	protein localization to endoplasmic reticulum
LLY41_14895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LLY41_14900	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LLY41_14910	COG1987	bacterial-type flagellum assembly
LLY41_14915	COG1338	Plays a role in the flagellum-specific transport system
LLY41_14920	COG3190	flagellar
LLY41_14925	COG2201	protein-glutamate methylesterase activity
LLY41_14935	COG1776	CheC inhibitor of MCP methylation
LLY41_14935	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LLY41_14940	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LLY41_14945	COG1580	Controls the rotational direction of flagella during chemotaxis
LLY41_14950	COG1582	Flagellar protein (FlbD)
LLY41_14955	COG4786	Flagellar basal body rod
LLY41_14965	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LLY41_14980	COG2882	bacterial-type flagellum organization
LLY41_14985	COG1157	protein secretion by the type III secretion system
LLY41_14990	COG1317	bacterial-type flagellum organization
LLY41_14995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LLY41_15000	COG1766	The M ring may be actively involved in energy transduction
LLY41_15005	COG1677	Flagellar hook-basal body complex protein FliE
LLY41_15010	COG1558	bacterial-type flagellum-dependent cell motility
LLY41_15015	COG1815	bacterial-type flagellum-dependent cell motility
LLY41_15020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LLY41_15025	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LLY41_15035	COG4974	Belongs to the 'phage' integrase family
LLY41_15040	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LLY41_15050	COG0758	DNA mediated transformation
LLY41_15055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LLY41_15065	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LLY41_15095	COG0336	Belongs to the RNA methyltransferase TrmD family
LLY41_15100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LLY41_15110	COG1837	Belongs to the UPF0109 family
LLY41_15120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LLY41_15125	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LLY41_15145	COG0714	Associated with various cellular activities
LLY41_15160	COG1131	(ABC) transporter
LLY41_15175	COG0552	protein localization to endoplasmic reticulum
LLY41_15190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLY41_15195	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_15200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LLY41_15210	COG1349	DNA-binding transcription factor activity
LLY41_15215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LLY41_15220	COG1461	Dihydroxyacetone kinase
LLY41_15225	COG1302	Protein conserved in bacteria
LLY41_15230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LLY41_15240	COG1564	THIamine pyrophosphokinase
LLY41_15245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LLY41_15255	COG0515	serine threonine protein kinase
LLY41_15255	COG2815	serine threonine protein kinase
LLY41_15260	COG0631	protein serine/threonine phosphatase activity
LLY41_15265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LLY41_15270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLY41_15270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LLY41_15275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LLY41_15295	COG1758	RNA polymerase activity
LLY41_15300	COG0194	GDP metabolic process
LLY41_15310	COG1561	YicC-like family, N-terminal region
LLY41_15315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLY41_15335	COG0167	dihydroorotate dehydrogenase activity
LLY41_15350	COG0505	Belongs to the CarA family
LLY41_15355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LLY41_15360	COG0540	Belongs to the ATCase OTCase family
LLY41_15370	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LLY41_15375	COG0564	pseudouridine synthase activity
LLY41_15380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LLY41_15390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LLY41_15395	COG3599	regulation of cell shape
LLY41_15400	COG2302	S4 RNA-binding domain
LLY41_15405	COG0762	integral membrane protein
LLY41_15410	COG1799	cell septum assembly
LLY41_15415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LLY41_15420	COG1496	oxidoreductase activity
LLY41_15425	COG1873	PFAM PRC-barrel domain
LLY41_15430	COG1191	sigma factor activity
LLY41_15435	COG1191	sigma factor activity
LLY41_15450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LLY41_15460	COG3856	small basic protein
LLY41_15465	COG3879	Bacterial protein of unknown function (DUF881)
LLY41_15470	COG3879	Bacterial protein of unknown function (DUF881)
LLY41_15480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LLY41_15485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LLY41_15490	COG0772	Belongs to the SEDS family
LLY41_15495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LLY41_15500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLY41_15510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LLY41_15520	COG0768	penicillin binding
LLY41_15535	COG0275	rRNA processing
LLY41_15540	COG2001	Belongs to the MraZ family
LLY41_15545	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LLY41_15555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LLY41_15560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LLY41_15565	COG0511	ligase activity, forming carbon-carbon bonds
LLY41_15570	COG0439	Biotin carboxylase
LLY41_15585	COG1024	Enoyl-CoA hydratase
LLY41_15590	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LLY41_15595	COG1399	metal-binding, possibly nucleic acid-binding protein
LLY41_15600	COG1323	Belongs to the UPF0348 family
LLY41_15605	COG3480	Lon protease (S16) C-terminal proteolytic domain
LLY41_15610	COG1752	Esterase of the alpha-beta hydrolase superfamily
LLY41_15615	COG3314	Sporulation integral membrane protein YlbJ
LLY41_15620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LLY41_15625	COG0742	ribosomal rna small subunit methyltransferase
LLY41_15640	COG4471	UPF0298 protein
LLY41_15645	COG3679	Belongs to the UPF0342 family
LLY41_15675	COG2340	Cysteine-rich secretory protein family
LLY41_15680	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LLY41_15700	COG0628	permease
LLY41_15715	COG3336	cytochrome c oxidase
LLY41_15745	COG1612	heme a metabolic process
LLY41_15750	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LLY41_15755	COG0772	Belongs to the SEDS family
LLY41_15760	COG4838	Belongs to the UPF0358 family
LLY41_15770	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LLY41_15785	COG4896	Protein conserved in bacteria
LLY41_15800	COG1217	gtp-binding protein TYPA
LLY41_15815	COG0483	inositol monophosphate 1-phosphatase activity
LLY41_15825	COG4493	Belongs to the UPF0637 family
LLY41_15830	COG4476	Belongs to the UPF0223 family
LLY41_15840	COG1982	Orn Lys Arg decarboxylase major
LLY41_15865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LLY41_15885	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLY41_15890	COG0022	dehydrogenase e1 component
LLY41_15910	COG0242	peptide deformylase activity
LLY41_15915	COG0561	phosphatase activity
LLY41_15925	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LLY41_15930	COG0569	domain protein
LLY41_15935	COG1132	(ABC) transporter
LLY41_15940	COG1132	(ABC) transporter
LLY41_15945	COG1473	amidohydrolase
LLY41_15950	COG2171	N-acyltransferase activity
LLY41_15955	COG0583	DNA-binding transcription factor activity
LLY41_15960	COG0477	Major facilitator Superfamily
LLY41_15980	COG4703	Protein of unknown function (DUF1797)
LLY41_16010	COG4990	cell redox homeostasis
LLY41_16015	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_16020	COG1408	metallophosphoesterase
LLY41_16025	COG1376	ErfK ybiS ycfS ynhG family protein
LLY41_16045	COG0835	chemotaxis
LLY41_16045	COG0784	Response regulator, receiver
LLY41_16060	COG1714	RDD family
LLY41_16070	COG0436	Aminotransferase
LLY41_16075	COG2084	Dehydrogenase
LLY41_16085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LLY41_16100	COG0390	transport system, permease component
LLY41_16105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLY41_16115	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_16125	COG4873	Protein conserved in bacteria
LLY41_16145	COG3949	Membrane
LLY41_16150	COG0542	response to heat
LLY41_16160	COG1846	Transcriptional regulator
LLY41_16165	COG0737	Belongs to the 5'-nucleotidase family
LLY41_16170	COG3852	Histidine kinase
LLY41_16175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LLY41_16180	COG2223	nitrite transmembrane transporter activity
LLY41_16200	COG0644	oxidoreductase
LLY41_16205	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LLY41_16220	COG0436	Aminotransferase
LLY41_16225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LLY41_16230	COG0640	Transcriptional regulator
LLY41_16235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LLY41_16240	COG5002	protein histidine kinase activity
LLY41_16245	COG0840	transmembrane signaling receptor activity
LLY41_16250	COG3594	Acyltransferase
LLY41_16280	COG1556	Lactate utilization protein
LLY41_16285	COG1139	Iron-sulfur cluster binding protein
LLY41_16290	COG0247	lactate metabolic process
LLY41_16315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LLY41_16320	COG3835	regulator
LLY41_16325	COG0277	FAD linked oxidase domain protein
LLY41_16330	COG0247	lactate metabolic process
LLY41_16345	COG1191	sigma factor activity
LLY41_16355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LLY41_16360	COG1757	Na H antiporter
LLY41_16365	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LLY41_16370	COG1988	membrane-bound metal-dependent
LLY41_16375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LLY41_16380	COG0366	Alpha amylase catalytic
LLY41_16385	COG0366	Alpha amylase catalytic
LLY41_16390	COG1263	PTS System
LLY41_16390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLY41_16395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LLY41_16400	COG3339	Conserved Protein
LLY41_16425	COG0084	hydrolase, TatD family'
LLY41_16440	COG1404	Belongs to the peptidase S8 family
LLY41_16440	COG4412	M6 family metalloprotease domain protein
LLY41_16445	COG0488	(ABC) transporter
LLY41_16450	COG0488	(ABC) transporter
LLY41_16480	COG0584	glycerophosphoryl diester phosphodiesterase
LLY41_16495	COG1966	Carbon starvation protein
LLY41_16525	COG2176	DNA-directed DNA polymerase activity
LLY41_16535	COG0004	ammonium transporteR
LLY41_16550	COG4948	Mandelate Racemase Muconate Lactonizing
LLY41_16560	COG3314	Sporulation integral membrane protein YlbJ
LLY41_16580	COG0506	proline dehydrogenase activity
LLY41_16595	COG2364	Membrane
LLY41_16620	COG2358	TRAP transporter, solute receptor (TAXI family
LLY41_16625	COG2382	esterase
LLY41_16635	COG2153	protein acetylation
LLY41_16640	COG2323	membrane
LLY41_16650	COG0210	DNA helicase
LLY41_16670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LLY41_16705	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LLY41_16710	COG0475	glutathione-regulated potassium exporter activity
LLY41_16710	COG0569	domain protein
LLY41_16715	COG2239	Acts as a magnesium transporter
LLY41_16720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LLY41_16735	COG2357	RelA SpoT domain protein
LLY41_16745	COG4116	CYTH
LLY41_16750	COG0741	lytic transglycosylase activity
LLY41_16755	COG2346	COG2346, Truncated hemoglobins
LLY41_16760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LLY41_16765	COG1164	Oligoendopeptidase f
LLY41_16775	COG4862	establishment of competence for transformation
LLY41_16780	COG1393	Belongs to the ArsC family
LLY41_16785	COG0456	acetyltransferase
LLY41_16800	COG4608	Belongs to the ABC transporter superfamily
LLY41_16805	COG0444	Belongs to the ABC transporter superfamily
LLY41_16810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLY41_16815	COG0601	transmembrane transport
LLY41_16820	COG4166	transmembrane transport
LLY41_16825	COG0180	Tryptophanyl-tRNA synthetase
LLY41_16840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLY41_16845	COG0601	transmembrane transport
LLY41_16855	COG4608	Belongs to the ABC transporter superfamily
LLY41_16860	COG0444	Belongs to the ABC transporter superfamily
LLY41_16865	COG5504	Zn-dependent protease
LLY41_16875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LLY41_16890	COG1744	ABC transporter substrate-binding protein PnrA-like
LLY41_16900	COG2267	carboxylic ester hydrolase activity
LLY41_16910	COG0542	response to heat
LLY41_16925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLY41_16935	COG0505	Belongs to the CarA family
LLY41_16950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LLY41_16965	COG1763	Mo-molybdopterin cofactor biosynthetic process
LLY41_16970	COG0303	'Molybdopterin
LLY41_16975	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
LLY41_16980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LLY41_16985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLY41_16990	COG0535	radical SAM domain protein
LLY41_16995	COG2151	metal-sulfur cluster biosynthetic enzyme
LLY41_17000	COG1073	alpha beta
LLY41_17005	COG0561	phosphatase activity
LLY41_17030	COG1307	EDD domain protein, DegV family
LLY41_17040	COG2996	Protein conserved in bacteria
LLY41_17045	COG1666	GTP binding
LLY41_17050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLY41_17055	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_17060	COG1609	Transcriptional regulator
LLY41_17065	COG1874	Beta-galactosidase
LLY41_17065	COG0366	Alpha amylase catalytic
LLY41_17070	COG3833	ABC-type maltose transport systems, permease component
LLY41_17075	COG1175	transmembrane transport
LLY41_17080	COG2182	Extracellular solute-binding protein
LLY41_17090	COG0534	Mate efflux family protein
LLY41_17095	COG0367	asparagine synthase
LLY41_17105	COG5001	Diguanylate cyclase
LLY41_17105	COG3300	MHYT domain
LLY41_17115	COG0179	Fumarylacetoacetate (FAA) hydrolase
LLY41_17120	COG2311	Membrane
LLY41_17165	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LLY41_17175	COG2814	Major facilitator Superfamily
LLY41_17185	COG0183	Belongs to the thiolase family
LLY41_17190	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_17205	COG0398	Pfam SNARE associated Golgi protein
LLY41_17210	COG1316	TRANSCRIPTIONal
LLY41_17215	COG1506	peptidase
LLY41_17215	COG0823	Involved in the tonB-independent uptake of proteins
LLY41_17215	COG4946	Tricorn protease homolog
LLY41_17225	COG4903	ComK protein
LLY41_17240	COG0501	Belongs to the peptidase M48B family
LLY41_17250	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LLY41_17255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LLY41_17270	COG1024	Enoyl-CoA hydratase
LLY41_17275	COG0318	PFAM AMP-dependent synthetase and ligase
LLY41_17280	COG0095	Lipoate-protein ligase
LLY41_17285	COG1234	tRNA 3'-trailer cleavage
LLY41_17295	COG1511	domain protein
LLY41_17300	COG1309	transcriptional regulator
LLY41_17305	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LLY41_17310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LLY41_17315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LLY41_17320	COG2329	Antibiotic biosynthesis monooxygenase
LLY41_17325	COG2197	response regulator
LLY41_17330	COG4585	Histidine kinase
LLY41_17340	COG3069	C4-dicarboxylate transmembrane transporter activity
LLY41_17345	COG0671	phosphoesterase, PA-phosphatase related
LLY41_17350	COG1473	amidohydrolase
LLY41_17360	COG4473	ABC transporter
LLY41_17365	COG1131	(ABC) transporter
LLY41_17370	COG0537	adenosine 5'-monophosphoramidase activity
LLY41_17375	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LLY41_17390	COG1846	Transcriptional regulator
LLY41_17415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLY41_17425	COG3481	metal-dependent phosphohydrolase, HD sub domain
LLY41_17430	COG4717	serine-type aminopeptidase activity
LLY41_17435	COG0420	3'-5' exonuclease activity
LLY41_17440	COG1280	lysine exporter protein (LysE YggA)
LLY41_17445	COG1668	transmembrane transport
LLY41_17450	COG4152	abc transporter atp-binding protein
LLY41_17460	COG1024	Enoyl-CoA hydratase
LLY41_17465	COG0318	PFAM AMP-dependent synthetase and ligase
LLY41_17470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LLY41_17475	COG0561	phosphatase activity
LLY41_17485	COG4721	ABC-type cobalt transport system, permease component
LLY41_17490	COG1122	ATPase activity
LLY41_17495	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LLY41_17505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LLY41_17510	COG3679	Belongs to the UPF0342 family
LLY41_17520	COG0189	ligase activity
LLY41_17525	COG0189	ligase activity
LLY41_17530	COG0189	ligase activity
LLY41_17535	COG0189	ligase activity
LLY41_17555	COG1937	Protein conserved in bacteria
LLY41_17560	COG2508	Transcriptional regulator
LLY41_17565	COG3842	ATPase activity
LLY41_17585	COG1132	(ABC) transporter
LLY41_17590	COG1132	(ABC) transporter
LLY41_17600	COG0393	Putative heavy-metal-binding
LLY41_17620	COG1595	DNA-templated transcription, initiation
LLY41_17625	COG2814	Major facilitator Superfamily
LLY41_17640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLY41_17655	COG3852	Histidine kinase
LLY41_17660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLY41_17665	COG1253	flavin adenine dinucleotide binding
LLY41_17670	COG0789	Transcriptional regulator
LLY41_17675	COG1253	flavin adenine dinucleotide binding
LLY41_17680	COG3850	Histidine kinase
LLY41_17680	COG5002	protein histidine kinase activity
LLY41_17685	COG0745	RESPONSE REGULATOR receiver
LLY41_17695	COG0640	Transcriptional regulator
LLY41_17705	COG2252	PERMEase
LLY41_17715	COG1295	ribonuclease BN
LLY41_17720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLY41_17730	COG0730	response to heat
LLY41_17735	COG0425	Belongs to the sulfur carrier protein TusA family
LLY41_17740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLY41_17740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLY41_17745	COG0425	Belongs to the sulfur carrier protein TusA family
LLY41_17745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLY41_17750	COG2210	Belongs to the sulfur carrier protein TusA family
LLY41_17755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLY41_17760	COG1054	Belongs to the UPF0176 family
LLY41_17765	COG1937	Protein conserved in bacteria
LLY41_17775	COG2719	SpoVR family
LLY41_17795	COG2197	response regulator
LLY41_17800	COG4585	Histidine kinase
LLY41_17800	COG2203	Gaf domain
LLY41_17805	COG4221	oxidoreductase activity
LLY41_17810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LLY41_17815	COG3153	acetyltransferase
LLY41_17815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LLY41_17825	COG3118	belongs to the thioredoxin family
LLY41_17835	COG0564	pseudouridine synthase activity
LLY41_17840	COG2261	transglycosylase associated protein
LLY41_17845	COG3973	AAA domain
LLY41_17850	COG5566	PFAM Mor transcription activator
LLY41_17860	COG1392	Phosphate transport regulator
LLY41_17865	COG0306	phosphate transporter
LLY41_17870	COG4187	Peptidase family M20/M25/M40
LLY41_17875	COG2252	PERMEase
LLY41_17880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLY41_17885	COG1823	symporter activity
LLY41_17890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLY41_17895	COG2094	Belongs to the DNA glycosylase MPG family
LLY41_17910	COG0460	homoserine dehydrogenase
LLY41_17940	COG2766	serine protein kinase
LLY41_17945	COG0778	Nitroreductase
LLY41_17950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LLY41_17960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LLY41_17965	COG3382	B3 4 domain protein
LLY41_17980	COG0673	inositol 2-dehydrogenase activity
LLY41_17985	COG0673	inositol 2-dehydrogenase activity
LLY41_18000	COG2972	Histidine kinase
LLY41_18005	COG1653	transport
LLY41_18020	COG5002	protein histidine kinase activity
LLY41_18130	COG0735	belongs to the Fur family
LLY41_18140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LLY41_18165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LLY41_18170	COG0067	glutamate synthase
LLY41_18170	COG0069	glutamate synthase activity
LLY41_18170	COG0070	glutamate synthase
LLY41_18175	COG4129	membrane
LLY41_18180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLY41_18185	COG0601	transmembrane transport
LLY41_18190	COG0747	negative chemotaxis
LLY41_18195	COG4608	Belongs to the ABC transporter superfamily
LLY41_18200	COG0444	Belongs to the ABC transporter superfamily
LLY41_18205	COG1132	(ABC) transporter
LLY41_18225	COG1028	Short-chain dehydrogenase reductase Sdr
LLY41_18235	COG1194	a g-specific adenine glycosylase
LLY41_18240	COG1988	membrane-bound metal-dependent
LLY41_18265	COG4221	oxidoreductase activity
LLY41_18275	COG1090	epimerase
LLY41_18300	COG2304	oxidoreductase activity
LLY41_18305	COG1132	(ABC) transporter
LLY41_18310	COG1132	(ABC) transporter
LLY41_18315	COG0584	glycerophosphoryl diester phosphodiesterase
LLY41_18340	COG0683	leucine binding
LLY41_18345	COG0506	proline dehydrogenase activity
LLY41_18350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LLY41_18355	COG2508	Transcriptional regulator
LLY41_18370	COG0702	epimerase
LLY41_18375	COG0069	glutamate synthase activity
LLY41_18400	COG3189	MarR family transcriptional regulator
LLY41_18410	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LLY41_18425	COG0386	Belongs to the glutathione peroxidase family
LLY41_18440	COG2764	glyoxalase bleomycin resistance protein dioxygenase
LLY41_18445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LLY41_18455	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LLY41_18465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LLY41_18475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLY41_18480	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LLY41_18500	COG2323	membrane
LLY41_18505	COG0405	Gamma-glutamyltransferase
LLY41_18515	COG0535	radical SAM domain protein
LLY41_18525	COG0387	Pfam Sodium calcium exchanger
LLY41_18540	COG0477	Major facilitator Superfamily
LLY41_18545	COG2217	Heavy metal translocating P-type atpase
LLY41_18560	COG4840	Belongs to the UPF0435 family
LLY41_18565	COG0693	protein deglycase activity
LLY41_18570	COG2188	Transcriptional regulator
LLY41_18585	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
LLY41_18590	COG1396	sequence-specific DNA binding
LLY41_18620	COG0681	Belongs to the peptidase S26 family
LLY41_18630	COG3764	Sortase (surface protein transpeptidase)
LLY41_18640	COG2313	pseudouridylate synthase activity
LLY41_18645	COG1522	sequence-specific DNA binding
LLY41_18645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LLY41_18650	COG1115	amino acid carrier protein
LLY41_18655	COG1846	Transcriptional regulator
LLY41_18660	COG2814	Major facilitator Superfamily
LLY41_18665	COG1360	Flagellar Motor Protein
LLY41_18670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LLY41_18700	COG2986	histidine ammonia-lyase
LLY41_18705	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_18720	COG2309	aminopeptidase activity
LLY41_18740	COG4145	pantothenate transmembrane transporter activity
LLY41_18755	COG1970	mechanosensitive ion channel activity
LLY41_18760	COG0670	Belongs to the BI1 family
LLY41_18790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LLY41_18795	COG0805	protein transport
LLY41_18810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLY41_18815	COG0312	modulator of DNA gyrase
LLY41_18820	COG0312	modulator of DNA gyrase
LLY41_18825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLY41_18845	COG0405	Gamma-glutamyltransferase
LLY41_18850	COG1607	acyl-coa hydrolase
LLY41_18865	COG0598	Magnesium transport protein CorA
LLY41_18880	COG2244	polysaccharide biosynthetic process
LLY41_18885	COG3314	Sporulation integral membrane protein YlbJ
LLY41_18890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LLY41_18910	COG2197	response regulator
LLY41_18925	COG1842	Phage shock protein A
LLY41_18935	COG1994	Peptidase M50
LLY41_18940	COG2720	vancomycin resistance protein
LLY41_18970	COG0626	cystathionine gamma-synthase activity
LLY41_18980	COG0697	spore germination
LLY41_18985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LLY41_18995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLY41_18995	COG0723	plastoquinol--plastocyanin reductase activity
LLY41_19000	COG0154	amidase activity
LLY41_19005	COG0513	Belongs to the DEAD box helicase family
LLY41_19010	COG0840	transmembrane signaling receptor activity
LLY41_19015	COG5002	protein histidine kinase activity
LLY41_19030	COG1115	amino acid carrier protein
LLY41_19040	COG2814	Major facilitator Superfamily
LLY41_19050	COG0235	Class ii aldolase
LLY41_19060	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LLY41_19070	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_19080	COG2706	6-phosphogluconolactonase activity
LLY41_19090	COG0604	alcohol dehydrogenase
LLY41_19095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LLY41_19100	COG0024	Methionine aminopeptidase
LLY41_19115	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LLY41_19125	COG3275	phosphorelay sensor kinase activity
LLY41_19135	COG1966	Carbon starvation protein
LLY41_19140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LLY41_19155	COG4895	conserved protein (DUF2196)
LLY41_19165	COG2176	DNA-directed DNA polymerase activity
LLY41_19190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LLY41_19210	COG2318	DinB family
LLY41_19215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LLY41_19220	COG3708	Transcriptional regulator
LLY41_19220	COG2207	Transcriptional regulator
LLY41_19225	COG0753	catalase activity
LLY41_19225	COG0693	protein deglycase activity
LLY41_19230	COG2205	protein histidine kinase activity
LLY41_19245	COG0406	alpha-ribazole phosphatase activity
LLY41_19260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLY41_19270	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_19275	COG1301	dicarboxylic acid transport
LLY41_19280	COG4565	transcriptional regulatory protein
LLY41_19285	COG3290	protein histidine kinase activity
LLY41_19295	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLY41_19310	COG0579	oxidoreductase
LLY41_19315	COG0247	lactate metabolic process
LLY41_19325	COG1802	Transcriptional regulator
LLY41_19335	COG2358	TRAP transporter, solute receptor (TAXI family
LLY41_19340	COG1247	-acetyltransferase
LLY41_19345	COG3135	benzoate transporter
LLY41_19355	COG1309	transcriptional regulator
LLY41_19360	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_19395	COG0789	Transcriptional regulator
LLY41_19420	COG0318	PFAM AMP-dependent synthetase and ligase
LLY41_19430	COG2233	PERMEase
LLY41_19440	COG0501	Belongs to the peptidase M48B family
LLY41_19445	COG2361	Protein of unknown function DUF86
LLY41_19450	COG2155	Conserved Protein
LLY41_19460	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_19465	COG0733	neurotransmitter:sodium symporter activity
LLY41_19480	COG3844	kynureninase activity
LLY41_19485	COG1309	transcriptional regulator
LLY41_19500	COG1902	pentaerythritol trinitrate reductase activity
LLY41_19520	COG2814	Major facilitator Superfamily
LLY41_19525	COG0789	Transcriptional regulator
LLY41_19525	COG4978	Transcriptional regulator
LLY41_19530	COG1278	Cold shock
LLY41_19535	COG0577	efflux transmembrane transporter activity
LLY41_19540	COG1136	(ABC) transporter
LLY41_19545	COG2205	protein histidine kinase activity
LLY41_19550	COG0745	RESPONSE REGULATOR receiver
LLY41_19555	COG0778	Nitroreductase
LLY41_19555	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LLY41_19565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LLY41_19570	COG2169	Transcriptional regulator
LLY41_19575	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LLY41_19580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LLY41_19590	COG2391	methyltransferase activity
LLY41_19620	COG0745	RESPONSE REGULATOR receiver
LLY41_19625	COG5002	protein histidine kinase activity
LLY41_19700	COG3212	peptidase
LLY41_19715	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LLY41_19720	COG1131	(ABC) transporter
LLY41_19735	COG2310	stress, protein
LLY41_19755	COG0702	epimerase
LLY41_19770	COG0659	secondary active sulfate transmembrane transporter activity
LLY41_19790	COG1247	-acetyltransferase
LLY41_19810	COG2814	Major facilitator Superfamily
LLY41_19815	COG3973	AAA domain
LLY41_19830	COG0346	lactoylglutathione lyase activity
LLY41_19850	COG2318	DinB family
LLY41_19855	COG0456	acetyltransferase
LLY41_19885	COG2072	flavoprotein involved in K transport
LLY41_19895	COG3842	ATPase activity
LLY41_19900	COG1178	ABC-type Fe3 transport system permease component
LLY41_19905	COG1840	ABC-type Fe3 transport system, periplasmic component
LLY41_19910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLY41_19910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLY41_19915	COG2210	Belongs to the sulfur carrier protein TusA family
LLY41_19920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLY41_19920	COG0425	Belongs to the sulfur carrier protein TusA family
LLY41_19925	COG0785	Cytochrome C biogenesis protein
LLY41_19930	COG0745	RESPONSE REGULATOR receiver
LLY41_19950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLY41_19960	COG3584	3D domain protein
LLY41_19960	COG3583	domain protein
LLY41_19965	COG0346	lactoylglutathione lyase activity
LLY41_19970	COG0640	Transcriptional regulator
LLY41_19990	COG0456	acetyltransferase
LLY41_19995	COG1131	(ABC) transporter
LLY41_20005	COG4149	molybdate abc transporter
LLY41_20010	COG0725	ABC transporter, periplasmic molybdate-binding protein
LLY41_20030	COG1301	dicarboxylic acid transport
LLY41_20065	COG1595	DNA-templated transcription, initiation
LLY41_20090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LLY41_20090	COG0456	acetyltransferase
LLY41_20100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LLY41_20105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LLY41_20110	COG1309	transcriptional regulator
LLY41_20130	COG0295	cytidine deaminase activity
LLY41_20145	COG0110	maltose O-acetyltransferase activity
LLY41_20170	COG2207	Transcriptional regulator
LLY41_20170	COG4753	response regulator
LLY41_20175	COG2972	Histidine kinase
LLY41_20185	COG1172	Belongs to the binding-protein-dependent transport system permease family
LLY41_20195	COG4213	ABC transporter substrate-binding protein
LLY41_20200	COG0861	Integral membrane protein TerC family
LLY41_20210	COG2312	Erythromycin esterase
LLY41_20225	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LLY41_20250	COG4572	Cation transport regulator
LLY41_20255	COG1522	sequence-specific DNA binding
LLY41_20260	COG0697	spore germination
LLY41_20270	COG3773	Cell wall hydrolase
LLY41_20320	COG1393	Belongs to the ArsC family
LLY41_20325	COG0456	acetyltransferase
LLY41_20335	COG1131	(ABC) transporter
LLY41_20360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLY41_20375	COG4912	Dna alkylation repair
LLY41_20405	COG4682	membrane
LLY41_20415	COG1846	Transcriptional regulator
LLY41_20420	COG0778	Nitroreductase
LLY41_20455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLY41_20460	COG2200	EAL domain
LLY41_20470	COG0577	efflux transmembrane transporter activity
LLY41_20475	COG1136	(ABC) transporter
LLY41_20480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LLY41_20515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LLY41_20520	COG2022	thiamine diphosphate biosynthetic process
LLY41_20535	COG0352	thiamine-phosphate diphosphorylase activity
LLY41_20555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LLY41_20560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LLY41_20570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LLY41_20575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LLY41_20590	COG1126	abc transporter atp-binding protein
LLY41_20595	COG0765	amino acid transport
LLY41_20600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLY41_20645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LLY41_20665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LLY41_20670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LLY41_20820	COG1733	regulation of RNA biosynthetic process
LLY41_20825	COG2814	Major facilitator Superfamily
LLY41_20845	COG5002	protein histidine kinase activity
LLY41_20850	COG2824	Alkylphosphonate utilization operon protein PhnA
LLY41_20855	COG0450	alkyl hydroperoxide reductase
LLY41_20870	COG2190	(PTS) system
LLY41_20870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLY41_20870	COG1263	PTS System
LLY41_20885	COG1132	(ABC) transporter
LLY41_20895	COG1082	Xylose isomerase domain protein TIM barrel
LLY41_20905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLY41_20930	COG2207	Transcriptional regulator
LLY41_20935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLY41_20940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLY41_20945	COG2329	Antibiotic biosynthesis monooxygenase
LLY41_20955	COG0492	ferredoxin-NADP+ reductase activity
LLY41_20960	COG1120	ATPase activity
LLY41_20965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LLY41_20970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLY41_20975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLY41_20980	COG3546	catalase activity
LLY41_20985	COG4608	Belongs to the ABC transporter superfamily
LLY41_20995	COG0601	transmembrane transport
LLY41_21000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLY41_21015	COG3738	Protein conserved in bacteria
LLY41_21020	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LLY41_21055	COG0861	Integral membrane protein TerC family
LLY41_21080	COG0788	formyltetrahydrofolate deformylase activity
LLY41_21085	COG2814	Major facilitator Superfamily
LLY41_21095	COG0527	aspartate kinase activity
LLY41_21105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LLY41_21110	COG0784	Response regulator, receiver
LLY41_21110	COG5002	protein histidine kinase activity
LLY41_21115	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LLY41_21120	COG2814	Major facilitator Superfamily
LLY41_21125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LLY41_21140	COG0584	glycerophosphoryl diester phosphodiesterase
LLY41_21155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLY41_21170	COG0697	spore germination
LLY41_21175	COG2234	aminopeptidase activity
LLY41_21185	COG0166	Belongs to the GPI family
LLY41_21190	COG5002	protein histidine kinase activity
LLY41_21195	COG3853	Toxic anion resistance protein (TelA)
LLY41_21200	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LLY41_21215	COG5002	protein histidine kinase activity
LLY41_21230	COG1309	transcriptional regulator
LLY41_21245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LLY41_21250	COG2323	membrane
LLY41_21255	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_21255	COG2202	Pas domain
LLY41_21260	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LLY41_21265	COG1227	inorganic diphosphatase activity
LLY41_21270	COG2070	2-Nitropropane dioxygenase
LLY41_21280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LLY41_21285	COG0154	amidase activity
LLY41_21295	COG5506	Protein of unknown function (DUF1694)
LLY41_21300	COG2224	Isocitrate lyase
LLY41_21315	COG1335	isochorismatase
LLY41_21320	COG1012	belongs to the aldehyde dehydrogenase family
LLY41_21325	COG4851	CamS sex pheromone cAM373 precursor
LLY41_21330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLY41_21335	COG0210	DNA helicase
LLY41_21340	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LLY41_21345	COG4496	protein, YerC YecD
LLY41_21365	COG0151	Belongs to the GarS family
LLY41_21370	COG0138	bifunctional purine biosynthesis protein purh
LLY41_21375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LLY41_21380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LLY41_21385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LLY41_21390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LLY41_21410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LLY41_21420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LLY41_21430	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LLY41_21450	COG1263	PTS System
LLY41_21450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LLY41_21450	COG2190	(PTS) system
LLY41_21455	COG3711	transcriptional antiterminator
LLY41_21460	COG2252	PERMEase
LLY41_21465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LLY41_21465	COG0519	Catalyzes the synthesis of GMP from XMP
LLY41_21470	COG1305	Transglutaminase-like
LLY41_21475	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LLY41_21480	COG0714	Associated with various cellular activities
LLY41_21570	COG1511	domain protein
LLY41_21575	COG1674	ftsk spoiiie
LLY41_21575	COG0433	COG0433 Predicted ATPase
LLY41_21585	COG5417	Belongs to the EsaB family
LLY41_21590	COG4842	Belongs to the WXG100 family
LLY41_21600	COG1732	Glycine betaine
LLY41_21645	COG5444	nuclease activity
LLY41_21700	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
LLY41_21705	COG0640	Transcriptional regulator
LLY41_21710	COG0459	protein refolding
LLY41_21715	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LLY41_21720	COG1266	CAAX protease self-immunity
LLY41_21730	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LLY41_21735	COG0315	cyclic pyranopterin monophosphate synthase activity
LLY41_21740	COG0488	(ABC) transporter
LLY41_21750	COG0456	acetyltransferase
LLY41_21755	COG1214	PFAM Peptidase M22, glycoprotease
LLY41_21760	COG0802	atpase or kinase
LLY41_21855	COG3091	SprT-like family
LLY41_21865	COG2183	response to ionizing radiation
LLY41_21870	COG2208	phosphoserine phosphatase activity
LLY41_21875	COG1191	sigma factor activity
LLY41_21880	COG2172	sigma factor antagonist activity
LLY41_21885	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_21890	COG2208	phosphoserine phosphatase activity
LLY41_21895	COG2172	sigma factor antagonist activity
LLY41_21900	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_21905	COG1366	Belongs to the anti-sigma-factor antagonist family
LLY41_21910	COG2337	Toxic component of a toxin-antitoxin (TA) module
LLY41_21915	COG0864	Transcriptional regulator
LLY41_21925	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LLY41_21930	COG0736	holo-[acyl-carrier-protein] synthase activity
LLY41_21935	COG0705	Rhomboid family
LLY41_21940	COG3428	Bacterial PH domain
LLY41_21945	COG3402	PFAM membrane-flanked domain
LLY41_21950	COG4294	response to UV
LLY41_21955	COG0513	Belongs to the DEAD box helicase family
LLY41_21965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLY41_21970	COG1181	Belongs to the D-alanine--D-alanine ligase family
LLY41_21985	COG0659	secondary active sulfate transmembrane transporter activity
LLY41_21990	COG0346	lactoylglutathione lyase activity
LLY41_22005	COG2096	Adenosyltransferase
LLY41_22020	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LLY41_22025	COG1492	cobalamin metabolic process
LLY41_22040	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LLY41_22045	COG1120	ATPase activity
LLY41_22050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLY41_22055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LLY41_22065	COG0772	Belongs to the SEDS family
LLY41_22080	COG0783	Belongs to the Dps family
LLY41_22095	COG3403	YqcI/YcgG family
LLY41_22105	COG4608	Belongs to the ABC transporter superfamily
LLY41_22110	COG0791	NLP P60 protein
LLY41_22115	COG4948	Mandelate Racemase Muconate Lactonizing
LLY41_22120	COG1619	proteins homologs of microcin C7 resistance protein MccF
LLY41_22125	COG4166	transmembrane transport
LLY41_22130	COG0444	Belongs to the ABC transporter superfamily
LLY41_22135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLY41_22140	COG0601	transmembrane transport
LLY41_22145	COG2362	D-Aminopeptidase
LLY41_22155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LLY41_22180	COG2814	Major facilitator Superfamily
LLY41_22185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LLY41_22190	COG1309	transcriptional regulator
LLY41_22195	COG4122	O-methyltransferase activity
LLY41_22200	COG4607	ABC-type enterochelin transport system periplasmic component
LLY41_22205	COG4604	ABC transporter, ATP-binding protein
LLY41_22210	COG4605	iron ion homeostasis
LLY41_22235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LLY41_22240	COG4856	YbbR-like protein
LLY41_22250	COG5662	AntiSigma factor
LLY41_22255	COG1595	DNA-templated transcription, initiation