locus-tag	class	description
BC359_00040	COG0726	polysaccharide deacetylase
BC359_00045	COG2194	sulfuric ester hydrolase activity
BC359_00055	COG0489	protein tyrosine kinase activity
BC359_00060	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_00080	COG0328	RNA-DNA hybrid ribonuclease activity
BC359_00080	COG3341	Caulimovirus viroplasmin
BC359_00085	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC359_00090	COG0732	type I restriction modification DNA specificity domain
BC359_00095	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BC359_00130	COG0582	viral genome integration into host DNA
BC359_00140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BC359_00145	COG0101	tRNA pseudouridine synthase activity
BC359_00150	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BC359_00155	COG1122	ATPase activity
BC359_00160	COG1122	ATPase activity
BC359_00165	COG0203	ribosomal protein L17
BC359_00170	COG0202	RNA polymerase activity
BC359_00175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BC359_00180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BC359_00185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BC359_00190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BC359_00195	COG0024	Methionine aminopeptidase
BC359_00200	COG0563	adenylate kinase activity
BC359_00205	COG0201	protein transport
BC359_00210	COG0200	Binds to the 23S rRNA
BC359_00215	COG1841	ribosomal large subunit assembly
BC359_00220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BC359_00240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC359_00250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BC359_00255	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BC359_00260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BC359_00265	COG0255	Belongs to the universal ribosomal protein uL29 family
BC359_00270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BC359_00275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BC359_00280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BC359_00285	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BC359_00290	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BC359_00295	COG0089	rRNA binding
BC359_00300	COG0088	Forms part of the polypeptide exit tunnel
BC359_00305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BC359_00315	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BC359_00325	COG0049	tRNA binding
BC359_00330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BC359_00335	COG1358	cellular component organization or biogenesis
BC359_00345	COG0085	RNA polymerase activity
BC359_00350	COG2813	Specifically methylates the guanine in position
BC359_00360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BC359_00365	COG0081	regulation of translation
BC359_00370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BC359_00375	COG0250	Participates in transcription elongation, termination and antitermination
BC359_00380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC359_00385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BC359_00395	COG3688	RNA-binding protein containing a PIN domain
BC359_00410	COG0215	cysteine-tRNA ligase activity
BC359_00415	COG1045	serine acetyltransferase
BC359_00420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BC359_00425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BC359_00430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BC359_00435	COG4956	integral membrane protein (PIN domain superfamily)
BC359_00440	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BC359_00445	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BC359_00450	COG0542	response to heat
BC359_00455	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BC359_00460	COG3880	PFAM UvrB UvrC protein
BC359_00485	COG1523	belongs to the glycosyl hydrolase 13 family
BC359_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BC359_00495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BC359_00500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BC359_00505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BC359_00510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC359_00515	COG0512	Glutamine amidotransferase of anthranilate synthase
BC359_00520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BC359_00525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC359_00530	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BC359_00535	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BC359_00540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC359_00555	COG0515	serine threonine protein kinase
BC359_00560	COG2304	oxidoreductase activity
BC359_00580	COG1098	S1 RNA binding domain
BC359_00585	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BC359_00600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BC359_00605	COG3956	TIGRFAM MazG family protein
BC359_00610	COG2244	polysaccharide biosynthetic process
BC359_00615	COG2002	toxin-antitoxin pair type II binding
BC359_00620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BC359_00630	COG0193	aminoacyl-tRNA hydrolase activity
BC359_00635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BC359_00640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BC359_00645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BC359_00650	COG2088	sporulation resulting in formation of a cellular spore
BC359_00660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC359_00675	COG4466	Protein conserved in bacteria
BC359_00685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC359_00695	COG0084	hydrolase, TatD family'
BC359_00705	COG2002	toxin-antitoxin pair type II binding
BC359_00710	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BC359_00720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BC359_00725	COG4467	Involved in initiation control of chromosome replication
BC359_00730	COG1774	PSP1 C-terminal conserved region
BC359_00735	COG0470	DNA polymerase III
BC359_00740	COG3870	Protein conserved in bacteria
BC359_00745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BC359_00750	COG1982	Orn Lys Arg decarboxylase major
BC359_00855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BC359_00860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BC359_00865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BC359_00875	COG0590	tRNA wobble adenosine to inosine editing
BC359_00880	COG1335	isochorismatase
BC359_00885	COG3858	chitin binding
BC359_00885	COG1388	LysM domain
BC359_00890	COG1428	Deoxynucleoside kinase
BC359_00895	COG1428	Deoxynucleoside kinase
BC359_00910	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BC359_00925	COG0516	GMP reductase activity
BC359_00925	COG0517	IMP dehydrogenase activity
BC359_00960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC359_00970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BC359_00975	COG2501	S4 domain
BC359_00980	COG0592	DNA-directed DNA polymerase activity
BC359_00985	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BC359_00990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BC359_00995	COG0594	ribonuclease P activity
BC359_01000	COG0706	membrane insertase activity
BC359_01005	COG1847	R3H domain protein
BC359_01010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BC359_01015	COG0445	tRNA wobble uridine modification
BC359_01025	COG1475	DNA binding
BC359_01030	COG1192	Involved in chromosome partitioning
BC359_01035	COG1475	DNA binding
BC359_01045	COG3949	Membrane
BC359_01050	COG0668	transmembrane transport
BC359_01055	COG4481	Protein conserved in bacteria
BC359_01060	COG0012	GTP binding
BC359_01075	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BC359_01085	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BC359_01095	COG0305	Participates in initiation and elongation during chromosome replication
BC359_01100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BC359_01145	COG0745	RESPONSE REGULATOR receiver
BC359_01150	COG5002	protein histidine kinase activity
BC359_01155	COG4863	YycH protein
BC359_01160	COG4853	Protein conserved in bacteria
BC359_01165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BC359_01170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC359_01185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC359_01205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC359_01215	COG0732	type I restriction modification DNA specificity domain
BC359_01355	COG0210	DNA helicase
BC359_01400	COG3645	SOS response
BC359_01405	COG0732	type I restriction modification DNA specificity domain
BC359_01410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC359_01435	COG1401	restriction endodeoxyribonuclease activity
BC359_01490	COG2814	Major facilitator Superfamily
BC359_01495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC359_01510	COG1464	Belongs to the NlpA lipoprotein family
BC359_01515	COG3634	alkyl hydroperoxide reductase activity
BC359_01520	COG0450	alkyl hydroperoxide reductase
BC359_01525	COG2972	Histidine kinase
BC359_01530	COG3279	Response regulator of the LytR AlgR family
BC359_01535	COG2182	Extracellular solute-binding protein
BC359_01540	COG1621	beta-fructofuranosidase activity
BC359_01545	COG1621	beta-fructofuranosidase activity
BC359_01565	COG2966	Psort location CytoplasmicMembrane, score
BC359_01570	COG3610	response to peptide
BC359_01575	COG1368	sulfuric ester hydrolase activity
BC359_01585	COG0728	peptidoglycan biosynthetic process
BC359_01610	COG0438	transferase activity, transferring glycosyl groups
BC359_01620	COG1263	PTS System
BC359_01620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_01620	COG2190	(PTS) system
BC359_01625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC359_01630	COG0561	phosphatase activity
BC359_01635	COG0351	phosphomethylpyrimidine kinase
BC359_01640	COG0686	Belongs to the AlaDH PNT family
BC359_01645	COG2508	Transcriptional regulator
BC359_01645	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BC359_01650	COG1115	amino acid carrier protein
BC359_01655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BC359_01660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC359_01670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BC359_01680	COG2363	Small membrane protein
BC359_01690	COG3773	Cell wall hydrolase
BC359_01700	COG0280	phosphate acetyltransferase
BC359_01705	COG0095	Lipoate-protein ligase
BC359_01720	COG1078	dGTPase activity
BC359_01725	COG3465	dGTPase activity
BC359_01735	COG1994	Peptidase M50
BC359_01745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC359_01750	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BC359_01755	COG0010	Belongs to the arginase family
BC359_01775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_01780	COG2181	nitrate reductase activity
BC359_01780	COG0247	lactate metabolic process
BC359_01790	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC359_01795	COG1960	acyl-CoA dehydrogenase activity
BC359_01800	COG1960	acyl-CoA dehydrogenase activity
BC359_01810	COG1703	isobutyryl-CoA mutase activity
BC359_01810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_01810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_01815	COG3343	RNA polymerase activity
BC359_01820	COG0504	CTP synthase activity
BC359_01825	COG4821	SIS domain
BC359_01830	COG2204	response regulator
BC359_01835	COG0191	fructose-bisphosphate aldolase activity
BC359_01840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BC359_01845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BC359_01850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BC359_01860	COG1435	thymidine kinase activity
BC359_01870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BC359_01875	COG2890	protein-(glutamine-N5) methyltransferase activity
BC359_01895	COG1971	Probably functions as a manganese efflux pump
BC359_01900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC359_01905	COG0698	ribose 5-phosphate isomerase
BC359_01920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BC359_01925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BC359_01945	COG0356	it plays a direct role in the translocation of protons across the membrane
BC359_01950	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC359_01955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BC359_01960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC359_01965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BC359_01970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BC359_01975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BC359_01980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BC359_01985	COG4836	Membrane
BC359_02010	COG2385	sporulation resulting in formation of a cellular spore
BC359_02015	COG0739	heme binding
BC359_02020	COG1609	Transcriptional regulator
BC359_02030	COG4786	Flagellar basal body rod
BC359_02035	COG4786	Flagellar basal body rod
BC359_02060	COG0629	single-stranded DNA binding
BC359_02065	COG0791	NLP P60 protein
BC359_02065	COG1388	LysM domain
BC359_02070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC359_02080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC359_02090	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BC359_02095	COG2268	Band 7 protein
BC359_02100	COG1585	Membrane protein implicated in regulation of membrane protease activity
BC359_02105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC359_02110	COG1316	TRANSCRIPTIONal
BC359_02115	COG1739	Uncharacterized protein family UPF0029
BC359_02120	COG4585	Histidine kinase
BC359_02125	COG2197	response regulator
BC359_02145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC359_02150	COG1728	Protein conserved in bacteria
BC359_02155	COG1307	EDD domain protein, DegV family
BC359_02160	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BC359_02165	COG1040	competence protein
BC359_02175	COG2747	anti-sigma28 factor FlgM
BC359_02185	COG4786	Flagellar basal body rod
BC359_02185	COG1256	bacterial-type flagellum assembly
BC359_02190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC359_02200	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BC359_02205	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BC359_02210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC359_02215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC359_02240	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BC359_02245	COG1516	flagellar protein fliS
BC359_02255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BC359_02260	COG0653	protein targeting
BC359_02265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BC359_02275	COG2010	Cytochrome c
BC359_02280	COG2884	Cell division ATP-binding protein ftsE
BC359_02285	COG2177	Part of the ABC transporter FtsEX involved in
BC359_02290	COG3883	PFAM NLP P60 protein
BC359_02290	COG0791	NLP P60 protein
BC359_02295	COG3409	Peptidoglycan-binding domain 1 protein
BC359_02295	COG0793	Belongs to the peptidase S41A family
BC359_02300	COG1733	regulation of RNA biosynthetic process
BC359_02305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BC359_02315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC359_02320	COG0506	proline dehydrogenase activity
BC359_02325	COG1012	belongs to the aldehyde dehydrogenase family
BC359_02330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_02345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC359_02350	COG3595	metallopeptidase activity
BC359_02355	COG1983	PspC domain protein
BC359_02360	COG1950	PFAM Membrane protein of
BC359_02365	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BC359_02370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BC359_02375	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC359_02380	COG0546	phosphoglycolate phosphatase activity
BC359_02385	COG0110	maltose O-acetyltransferase activity
BC359_02390	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BC359_02395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BC359_02400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BC359_02405	COG0131	Imidazoleglycerol-phosphate dehydratase
BC359_02410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BC359_02415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BC359_02420	COG0107	imidazoleglycerol-phosphate synthase activity
BC359_02425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BC359_02425	COG0140	phosphoribosyl-ATP diphosphatase activity
BC359_02430	COG0457	Tetratricopeptide repeat
BC359_02435	COG0492	ferredoxin-NADP+ reductase activity
BC359_02440	COG1051	belongs to the nudix hydrolase family
BC359_02445	COG1660	Displays ATPase and GTPase activities
BC359_02450	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BC359_02455	COG1481	regulation of sporulation
BC359_02460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC359_02480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BC359_02520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC359_02525	COG1647	Serine aminopeptidase, S33
BC359_02530	COG0557	exoribonuclease II activity
BC359_02535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BC359_02555	COG0477	Major facilitator Superfamily
BC359_02565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC359_02570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_02575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_02580	COG1120	ATPase activity
BC359_02600	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC359_02600	COG1024	Enoyl-CoA hydratase
BC359_02605	COG0183	Belongs to the thiolase family
BC359_02610	COG1960	acyl-CoA dehydrogenase activity
BC359_02615	COG1393	Belongs to the ArsC family
BC359_02620	COG0509	glycine decarboxylation via glycine cleavage system
BC359_02630	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BC359_02640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC359_02645	COG2011	ABC-type metal ion transport system permease component
BC359_02650	COG1464	Belongs to the NlpA lipoprotein family
BC359_02655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC359_02660	COG0396	ATPase activity
BC359_02665	COG0719	Fe-S assembly protein
BC359_02670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC359_02675	COG0822	iron-sulfur transferase activity
BC359_02680	COG0719	Fe-S assembly protein
BC359_02685	COG1801	Protein of unknown function DUF72
BC359_02690	COG3377	Domain of unknown function (DUF1805)
BC359_02705	COG1757	Na H antiporter
BC359_02710	COG0733	neurotransmitter:sodium symporter activity
BC359_02720	COG0739	heme binding
BC359_02725	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BC359_02735	COG4470	Protein conserved in bacteria
BC359_02745	COG2445	Protein of unknown function DUF86
BC359_02750	COG0647	UMP catabolic process
BC359_02755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC359_02760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BC359_02765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC359_02770	COG0460	homoserine dehydrogenase
BC359_02775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BC359_02780	COG0083	homoserine kinase activity
BC359_02785	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BC359_02790	COG4837	Protein of unknown function (DUF1462)
BC359_02795	COG1252	NADH dehydrogenase
BC359_02800	COG4844	belongs to the
BC359_02810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BC359_02815	COG0316	Belongs to the HesB IscA family
BC359_02820	COG4974	Belongs to the 'phage' integrase family
BC359_02910	COG0492	ferredoxin-NADP+ reductase activity
BC359_02915	COG1252	NADH dehydrogenase
BC359_02925	COG3584	3D domain protein
BC359_02930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BC359_02935	COG2056	Na+-H+ antiporter family
BC359_02950	COG2050	protein possibly involved in aromatic compounds catabolism
BC359_02955	COG5018	Exonuclease
BC359_02970	COG2032	superoxide dismutase activity
BC359_02975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BC359_02980	COG2267	carboxylic ester hydrolase activity
BC359_02985	COG1522	sequence-specific DNA binding
BC359_02990	COG0436	Aminotransferase
BC359_02995	COG1098	S1 RNA binding domain
BC359_03000	COG2155	Conserved Protein
BC359_03005	COG1979	alcohol dehydrogenase
BC359_03015	COG2212	antiporter activity
BC359_03020	COG1863	multisubunit Na H antiporter MnhE subunit
BC359_03025	COG0651	ATP synthesis coupled electron transport
BC359_03030	COG1006	Multisubunit Na H antiporter MnhC subunit
BC359_03035	COG2111	Na H antiporter
BC359_03040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC359_03040	COG2111	Na H antiporter
BC359_03050	COG0166	Belongs to the GPI family
BC359_03060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BC359_03065	COG0346	lactoylglutathione lyase activity
BC359_03075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BC359_03090	COG0306	phosphate transporter
BC359_03100	COG0529	Catalyzes the synthesis of activated sulfate
BC359_03120	COG1285	pathogenesis
BC359_03125	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_03260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BC359_03265	COG0297	glycogen (starch) synthase activity
BC359_03270	COG0058	SHG alpha-glucan phosphorylase activity
BC359_03275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BC359_03280	COG1169	isochorismate synthase
BC359_03285	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BC359_03290	COG0596	Alpha beta hydrolase
BC359_03295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BC359_03300	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_03305	COG4948	Mandelate Racemase Muconate Lactonizing
BC359_03310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC359_03315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC359_03340	COG1294	oxidase, subunit
BC359_03345	COG1271	oxidase subunit
BC359_03350	COG0254	rRNA binding
BC359_03355	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC359_03360	COG0523	cobalamin synthesis protein
BC359_03365	COG0288	reversible hydration of carbon dioxide
BC359_03370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BC359_03375	COG1854	S-ribosylhomocysteine lyase activity
BC359_03385	COG0783	Belongs to the Dps family
BC359_03390	COG4824	toxin secretion phage lysis holin
BC359_03400	COG0494	nUDIX hydrolase
BC359_03405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC359_03410	COG1116	anion transmembrane transporter activity
BC359_03415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC359_03420	COG1506	peptidase
BC359_03430	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BC359_03435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BC359_03440	COG0438	transferase activity, transferring glycosyl groups
BC359_03440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BC359_03450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BC359_03455	COG2267	carboxylic ester hydrolase activity
BC359_03465	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BC359_03470	COG1242	4 iron, 4 sulfur cluster binding
BC359_03485	COG2814	Major facilitator Superfamily
BC359_03490	COG2610	gluconate transmembrane transporter activity
BC359_03495	COG0495	leucyl-tRNA aminoacylation
BC359_03500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_03510	COG2081	HI0933 family
BC359_03515	COG2244	polysaccharide biosynthetic process
BC359_03520	COG1187	pseudouridine synthase activity
BC359_03525	COG1349	DNA-binding transcription factor activity
BC359_03530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC359_03535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC359_03545	COG1523	belongs to the glycosyl hydrolase 13 family
BC359_03550	COG0510	thiamine kinase activity
BC359_03560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BC359_03565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_03575	COG1363	Peptidase, m42
BC359_03580	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BC359_03585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_03590	COG4848	Belongs to the UPF0354 family
BC359_03595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC359_03600	COG1674	ftsk spoiiie
BC359_03610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BC359_03625	COG4980	gas vesicle protein
BC359_03630	COG3118	belongs to the thioredoxin family
BC359_03635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC359_03635	COG1605	Chorismate mutase
BC359_03655	COG0123	including yeast histone deacetylase and acetoin utilization protein
BC359_03660	COG0517	IMP dehydrogenase activity
BC359_03665	COG0454	-acetyltransferase
BC359_03670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC359_03685	COG2203	Gaf domain
BC359_03685	COG2199	diguanylate cyclase activity
BC359_03690	COG1956	GAF domain-containing protein
BC359_03695	COG1309	transcriptional regulator
BC359_03700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC359_03705	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BC359_03710	COG1114	Component of the transport system for branched-chain amino acids
BC359_03715	COG1104	cysteine desulfurase activity
BC359_03720	COG0301	tRNA thio-modification
BC359_03730	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BC359_03735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BC359_03740	COG0616	signal peptide processing
BC359_03745	COG1714	RDD family
BC359_03755	COG3874	Sporulation protein YtfJ
BC359_03760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BC359_03765	COG0827	DNA restriction-modification system
BC359_03770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BC359_03785	COG0137	argininosuccinate synthase activity
BC359_03790	COG0165	Argininosuccinate lyase
BC359_03800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BC359_03810	COG4109	DRTGG domain
BC359_03825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BC359_03840	COG0587	DNA-directed DNA polymerase activity
BC359_03850	COG1725	Transcriptional regulator
BC359_03855	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BC359_03860	COG0825	malonyl-CoA metabolic process
BC359_03870	COG3030	protein affecting phage T7 exclusion by the F plasmid
BC359_03875	COG0628	permease
BC359_03880	COG2707	UPF0756 membrane protein
BC359_03885	COG0372	Belongs to the citrate synthase family
BC359_03890	COG0538	isocitrate dehydrogenase activity
BC359_03895	COG0039	L-malate dehydrogenase activity
BC359_03905	COG0745	RESPONSE REGULATOR receiver
BC359_03910	COG5002	protein histidine kinase activity
BC359_03915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC359_03915	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC359_03920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BC359_03925	COG1971	Probably functions as a manganese efflux pump
BC359_03930	COG0237	dephospho-CoA kinase activity
BC359_03935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC359_03940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BC359_03950	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BC359_03955	COG3611	Membrane attachment protein
BC359_03960	COG1484	DNA-dependent DNA replication
BC359_03970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC359_03975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BC359_03980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BC359_03985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BC359_03990	COG3326	Membrane
BC359_04010	COG1363	Peptidase, m42
BC359_04020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC359_04025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BC359_04040	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BC359_04045	COG1286	toxin biosynthetic process
BC359_04050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC359_04050	COG1796	DNA polymerase
BC359_04055	COG1193	negative regulation of DNA recombination
BC359_04060	COG3766	membrane
BC359_04065	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_04070	COG1309	transcriptional regulator
BC359_04075	COG1024	Enoyl-CoA hydratase
BC359_04080	COG2086	electron transfer activity
BC359_04085	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BC359_04090	COG3118	belongs to the thioredoxin family
BC359_04095	COG0322	excinuclease ABC activity
BC359_04100	COG0527	aspartate kinase activity
BC359_04105	COG1719	4-vinyl reductase, 4VR
BC359_04110	COG2009	succinate dehydrogenase
BC359_04115	COG1053	succinate dehydrogenase
BC359_04125	COG2197	response regulator
BC359_04135	COG0490	domain, Protein
BC359_04140	COG0475	glutathione-regulated potassium exporter activity
BC359_04155	COG1392	Phosphate transport regulator
BC359_04160	COG0306	phosphate transporter
BC359_04165	COG1846	Transcriptional regulator
BC359_04175	COG5401	PFAM Sporulation and spore germination
BC359_04190	COG0622	Phosphoesterase
BC359_04200	COG0028	Belongs to the TPP enzyme family
BC359_04205	COG0440	acetolactate synthase activity
BC359_04210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BC359_04215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC359_04225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BC359_04230	COG0066	3-isopropylmalate dehydratase activity
BC359_04235	COG0457	Tetratricopeptide repeat
BC359_04235	COG1477	protein flavinylation
BC359_04240	COG0544	peptidyl-prolyl cis-trans isomerase activity
BC359_04245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BC359_04250	COG1067	ATP-dependent peptidase activity
BC359_04250	COG0470	DNA polymerase III
BC359_04260	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BC359_04275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC359_04280	COG0181	hydroxymethylbilane synthase activity
BC359_04290	COG0113	porphobilinogen synthase activity
BC359_04300	COG1388	LysM domain
BC359_04315	COG0525	valine-tRNA ligase activity
BC359_04325	COG0285	dihydrofolate synthase activity
BC359_04335	COG2322	membrane
BC359_04345	COG1459	type II secretion system
BC359_04355	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BC359_04390	COG2003	Belongs to the UPF0758 family
BC359_04395	COG1077	Cell shape determining protein MreB Mrl
BC359_04400	COG1792	Involved in formation and maintenance of cell shape
BC359_04405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BC359_04415	COG2894	cell division
BC359_04420	COG0739	heme binding
BC359_04425	COG1994	Peptidase M50
BC359_04430	COG1530	ribonuclease E activity
BC359_04440	COG2868	ribosomal protein
BC359_04445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BC359_04450	COG3290	protein histidine kinase activity
BC359_04460	COG4492	Belongs to the UPF0735 family
BC359_04465	COG0077	Prephenate dehydratase
BC359_04470	COG1827	regulation of RNA biosynthetic process
BC359_04475	COG1104	cysteine desulfurase activity
BC359_04485	COG0157	Belongs to the NadC ModD family
BC359_04495	COG1388	LysM domain
BC359_04530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BC359_04540	COG1862	Preprotein translocase
BC359_04550	COG2323	membrane
BC359_04555	COG2244	polysaccharide biosynthetic process
BC359_04565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC359_04565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC359_04570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC359_04580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC359_04585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC359_04595	COG3103	Sh3 type 3 domain protein
BC359_04595	COG4991	sh3 domain protein
BC359_04595	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_04605	COG0124	histidyl-tRNA synthetase
BC359_04610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BC359_04620	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BC359_04625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BC359_04630	COG1959	2 iron, 2 sulfur cluster binding
BC359_04635	COG1104	cysteine desulfurase activity
BC359_04640	COG0482	sulfurtransferase activity
BC359_04650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC359_04660	COG0628	permease
BC359_04665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC359_04670	COG4472	Bacterial protein of unknown function (DUF965)
BC359_04680	COG3906	Belongs to the UPF0473 family
BC359_04685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BC359_04705	COG0572	uridine kinase
BC359_04710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BC359_04715	COG0768	penicillin binding
BC359_04730	COG2226	methyltransferase
BC359_04735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC359_04740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC359_04745	COG0626	cystathionine gamma-synthase activity
BC359_04755	COG1191	sigma factor activity
BC359_04770	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BC359_04775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BC359_04785	COG1534	Rna-binding protein
BC359_04790	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BC359_04795	COG1713	HD superfamily hydrolase involved in NAD metabolism
BC359_04800	COG0799	negative regulation of ribosome biogenesis
BC359_04805	COG2226	methyltransferase
BC359_04810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC359_04815	COG1555	photosystem II stabilization
BC359_04815	COG1596	polysaccharide export
BC359_04820	COG2131	deaminase
BC359_04825	COG0658	competence protein
BC359_04825	COG2333	competence protein COMEC
BC359_04835	COG1466	dna polymerase III delta subunit
BC359_04840	COG0268	Binds directly to 16S ribosomal RNA
BC359_04845	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BC359_04855	COG0481	GTPase activity
BC359_04860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC359_04870	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BC359_04875	COG0443	Heat shock 70 kDa protein
BC359_04880	COG0484	heat shock protein binding
BC359_04885	COG2264	protein methyltransferase activity
BC359_04890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BC359_04895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC359_04900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BC359_04905	COG1610	YqeY-like protein
BC359_04910	COG1030	water channel activity
BC359_04935	COG1702	phosphate starvation-inducible protein PhoH
BC359_04940	COG1480	7TM receptor with intracellular HD hydrolase
BC359_04950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BC359_04955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BC359_04965	COG1381	Involved in DNA repair and RecF pathway recombination
BC359_04970	COG0517	IMP dehydrogenase activity
BC359_04975	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BC359_04980	COG1671	Belongs to the UPF0178 family
BC359_04985	COG0358	DNA primase activity
BC359_04990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC359_04995	COG1960	acyl-CoA dehydrogenase activity
BC359_05005	COG2384	SAM-dependent methyltransferase
BC359_05010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BC359_05015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BC359_05030	COG0513	Belongs to the DEAD box helicase family
BC359_05045	COG1121	(ABC) transporter
BC359_05050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC359_05055	COG0735	belongs to the Fur family
BC359_05060	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BC359_05065	COG4709	membrane
BC359_05070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BC359_05080	COG2814	Major facilitator Superfamily
BC359_05100	COG2839	Protein conserved in bacteria
BC359_05135	COG0477	Major facilitator Superfamily
BC359_05145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC359_05150	COG0573	inorganic phosphate transmembrane transporter activity
BC359_05155	COG0581	inorganic phosphate transmembrane transporter activity
BC359_05165	COG0704	Plays a role in the regulation of phosphate uptake
BC359_05190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC359_05200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BC359_05210	COG0705	Rhomboid family
BC359_05210	COG0457	Tetratricopeptide repeat
BC359_05215	COG4483	Protein conserved in bacteria
BC359_05220	COG1940	carbohydrate kinase activity
BC359_05225	COG1368	sulfuric ester hydrolase activity
BC359_05240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_05250	COG1393	Belongs to the ArsC family
BC359_05255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BC359_05260	COG1459	type II secretion system
BC359_05265	COG4537	Required for transformation and DNA binding
BC359_05270	COG4970	Tfp pilus assembly protein FimT
BC359_05305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC359_05310	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BC359_05320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC359_05325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_05330	COG0095	Lipoate-protein ligase
BC359_05335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC359_05340	COG1321	iron dependent repressor
BC359_05350	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC359_05360	COG3872	metal-dependent enzyme
BC359_05370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BC359_05375	COG0006	proline dipeptidase activity
BC359_05380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BC359_05390	COG3854	ATPases associated with a variety of cellular activities
BC359_05430	COG0511	ligase activity, forming carbon-carbon bonds
BC359_05435	COG0439	Biotin carboxylase
BC359_05440	COG1302	Protein conserved in bacteria
BC359_05445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC359_05455	COG1722	exodeoxyribonuclease VII activity
BC359_05460	COG0142	geranyltranstransferase activity
BC359_05470	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BC359_05480	COG0497	DNA recombination
BC359_05485	COG0750	zinc metalloprotease
BC359_05490	COG0745	RESPONSE REGULATOR receiver
BC359_05500	COG1620	l-lactate permease
BC359_05505	COG0039	L-malate dehydrogenase activity
BC359_05510	COG3093	addiction module antidote protein HigA
BC359_05515	COG0584	glycerophosphoryl diester phosphodiesterase
BC359_05525	COG3290	protein histidine kinase activity
BC359_05525	COG3829	transcription factor binding
BC359_05550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC359_05555	COG0022	dehydrogenase e1 component
BC359_05560	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC359_05570	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_05570	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_05585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC359_05590	COG0765	amino acid transport
BC359_05595	COG1126	abc transporter atp-binding protein
BC359_05600	COG4129	membrane
BC359_05605	COG1376	ErfK ybiS ycfS ynhG family protein
BC359_05610	COG0346	lactoylglutathione lyase activity
BC359_05615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC359_05620	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC359_05625	COG0493	'glutamate synthase
BC359_05655	COG2508	Transcriptional regulator
BC359_05660	COG1012	belongs to the aldehyde dehydrogenase family
BC359_05665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC359_05675	COG1902	pentaerythritol trinitrate reductase activity
BC359_05680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC359_05685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_05690	COG0300	oxidoreductase activity
BC359_05700	COG4918	Iron-sulphur cluster biosynthesis
BC359_05705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC359_05715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BC359_05720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC359_05730	COG0667	Aldo Keto reductase
BC359_05735	COG0494	nUDIX hydrolase
BC359_05740	COG1300	Membrane
BC359_05745	COG0735	belongs to the Fur family
BC359_05755	COG4974	Belongs to the 'phage' integrase family
BC359_05775	COG1686	Belongs to the peptidase S11 family
BC359_05810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC359_05825	COG0697	spore germination
BC359_05835	COG4086	secreted protein
BC359_05840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BC359_05850	COG1547	Domain of unknown function (DUF309)
BC359_05860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BC359_05865	COG1686	Belongs to the peptidase S11 family
BC359_05870	COG2715	membrane protein required for spore maturation
BC359_05885	COG0700	Nucleoside recognition
BC359_05890	COG1187	pseudouridine synthase activity
BC359_05895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_05900	COG1333	cytochrome c biogenesis protein
BC359_05905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC359_05910	COG0745	RESPONSE REGULATOR receiver
BC359_05915	COG5002	protein histidine kinase activity
BC359_05920	COG0739	heme binding
BC359_05925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC359_05930	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BC359_05945	COG0514	ATP-dependent DNA helicase (RecQ)
BC359_05960	COG1408	metallophosphoesterase
BC359_05965	COG0789	Transcriptional regulator
BC359_05975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC359_05980	COG0492	ferredoxin-NADP+ reductase activity
BC359_05985	COG0252	asparaginase activity
BC359_05990	COG2339	peptidase activity
BC359_05995	COG3409	Peptidoglycan-binding domain 1 protein
BC359_05995	COG3773	Cell wall hydrolase
BC359_06010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BC359_06020	COG0539	negative regulation of cytoplasmic translation
BC359_06030	COG2271	Major facilitator Superfamily
BC359_06065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC359_06070	COG0776	regulation of translation
BC359_06075	COG0302	gtp cyclohydrolase
BC359_06085	COG0142	geranyltranstransferase activity
BC359_06090	COG2226	methyltransferase
BC359_06095	COG0142	geranyltranstransferase activity
BC359_06100	COG0105	UTP biosynthetic process
BC359_06105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BC359_06110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BC359_06115	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BC359_06125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC359_06130	COG0134	indole-3-glycerol-phosphate synthase activity
BC359_06135	COG0135	phosphoribosylanthranilate isomerase activity
BC359_06140	COG0133	tryptophan synthase activity
BC359_06145	COG0159	tryptophan synthase activity
BC359_06150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC359_06155	COG0287	Prephenate dehydrogenase
BC359_06160	COG0457	Tetratricopeptide repeat
BC359_06165	COG5582	Belongs to the UPF0302 family
BC359_06180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC359_06190	COG4347	Protein of unknown function (DUF1405)
BC359_06210	COG3679	Belongs to the UPF0342 family
BC359_06230	COG0742	ribosomal rna small subunit methyltransferase
BC359_06235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BC359_06240	COG3314	Sporulation integral membrane protein YlbJ
BC359_06245	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC359_06250	COG3480	Lon protease (S16) C-terminal proteolytic domain
BC359_06255	COG1323	Belongs to the UPF0348 family
BC359_06260	COG1399	metal-binding, possibly nucleic acid-binding protein
BC359_06265	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BC359_06270	COG1024	Enoyl-CoA hydratase
BC359_06280	COG0454	-acetyltransferase
BC359_06285	COG0439	Biotin carboxylase
BC359_06290	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BC359_06295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC359_06300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC359_06310	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BC359_06320	COG4839	cell division protein FtsL
BC359_06340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC359_06350	COG0772	Belongs to the SEDS family
BC359_06355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BC359_06360	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BC359_06365	COG0849	cell division
BC359_06370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BC359_06380	COG1191	sigma factor activity
BC359_06385	COG1191	sigma factor activity
BC359_06390	COG1873	PFAM PRC-barrel domain
BC359_06400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BC359_06405	COG1799	cell septum assembly
BC359_06410	COG0762	integral membrane protein
BC359_06415	COG2302	S4 RNA-binding domain
BC359_06420	COG3599	regulation of cell shape
BC359_06435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BC359_06440	COG0564	pseudouridine synthase activity
BC359_06445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BC359_06450	COG2233	PERMEase
BC359_06460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC359_06480	COG0167	dihydroorotate dehydrogenase activity
BC359_06490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BC359_06500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BC359_06505	COG1561	YicC-like family, N-terminal region
BC359_06510	COG2052	Domain of unknown function (DUF370)
BC359_06515	COG0194	GDP metabolic process
BC359_06525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC359_06530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BC359_06535	COG0242	peptide deformylase activity
BC359_06540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC359_06545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BC359_06545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC359_06555	COG0631	protein serine/threonine phosphatase activity
BC359_06560	COG2815	serine threonine protein kinase
BC359_06560	COG0515	serine threonine protein kinase
BC359_06570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC359_06575	COG1564	THIamine pyrophosphokinase
BC359_06585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BC359_06590	COG1302	Protein conserved in bacteria
BC359_06595	COG1461	Dihydroxyacetone kinase
BC359_06605	COG1760	l-serine dehydratase
BC359_06610	COG1760	l-serine dehydratase
BC359_06615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BC359_06620	COG1349	DNA-binding transcription factor activity
BC359_06625	COG0416	fatty acid biosynthetic process
BC359_06630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BC359_06635	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_06640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC359_06650	COG1196	nuclear chromosome segregation
BC359_06655	COG0552	protein localization to endoplasmic reticulum
BC359_06665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BC359_06670	COG0228	four-way junction DNA binding
BC359_06675	COG1837	Belongs to the UPF0109 family
BC359_06685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BC359_06695	COG0335	large ribosomal subunit rRNA binding
BC359_06710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BC359_06720	COG2257	FlhB HrpN YscU SpaS Family
BC359_06730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BC359_06735	COG0758	DNA mediated transformation
BC359_06740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC359_06750	COG4974	Belongs to the 'phage' integrase family
BC359_06760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BC359_06765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BC359_06770	COG1815	bacterial-type flagellum-dependent cell motility
BC359_06775	COG1558	bacterial-type flagellum-dependent cell motility
BC359_06780	COG1677	Flagellar hook-basal body complex protein FliE
BC359_06785	COG1766	The M ring may be actively involved in energy transduction
BC359_06790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC359_06795	COG1317	bacterial-type flagellum organization
BC359_06800	COG1157	protein secretion by the type III secretion system
BC359_06805	COG2882	bacterial-type flagellum organization
BC359_06820	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BC359_06825	COG4786	Flagellar basal body rod
BC359_06830	COG1582	Flagellar protein (FlbD)
BC359_06835	COG1580	Controls the rotational direction of flagella during chemotaxis
BC359_06840	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC359_06845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC359_06845	COG1776	CheC inhibitor of MCP methylation
BC359_06850	COG2201	protein-glutamate methylesterase activity
BC359_06855	COG3190	flagellar
BC359_06860	COG1338	Plays a role in the flagellum-specific transport system
BC359_06865	COG1987	bacterial-type flagellum assembly
BC359_06870	COG1684	flagellar biosynthetic protein fliR
BC359_06875	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC359_06880	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC359_06885	COG1419	protein localization to endoplasmic reticulum
BC359_06890	COG0455	bacterial-type flagellum organization
BC359_06895	COG2201	protein-glutamate methylesterase activity
BC359_06900	COG2198	Histidine kinase
BC359_06900	COG0643	Histidine kinase
BC359_06905	COG0835	chemotaxis
BC359_06910	COG1776	CheC inhibitor of MCP methylation
BC359_06915	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BC359_06920	COG1191	sigma factor activity
BC359_06935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BC359_06940	COG0528	UMP kinase activity
BC359_06945	COG0233	cytoplasmic translational termination
BC359_06955	COG4589	Belongs to the CDS family
BC359_06965	COG0750	zinc metalloprotease
BC359_06970	COG0442	prolyl-tRNA aminoacylation
BC359_06990	COG0779	Required for maturation of 30S ribosomal subunits
BC359_06995	COG0195	Participates in both transcription termination and antitermination
BC359_07000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BC359_07005	COG1358	cellular component organization or biogenesis
BC359_07010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BC359_07015	COG1550	Protein conserved in bacteria
BC359_07030	COG0196	riboflavin kinase activity
BC359_07035	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BC359_07040	COG1185	polyribonucleotide nucleotidyltransferase activity
BC359_07045	COG0726	polysaccharide deacetylase
BC359_07050	COG0612	Peptidase, M16
BC359_07055	COG1873	PFAM PRC-barrel domain
BC359_07060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC359_07065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC359_07070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BC359_07075	COG0527	aspartate kinase activity
BC359_07095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC359_07100	COG0740	serine-type endopeptidase activity
BC359_07120	COG2188	Transcriptional regulator
BC359_07125	COG1744	ABC transporter substrate-binding protein PnrA-like
BC359_07145	COG0612	Peptidase, M16
BC359_07155	COG0300	oxidoreductase activity
BC359_07170	COG1426	Protein conserved in bacteria
BC359_07175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BC359_07180	COG1546	Belongs to the CinA family
BC359_07180	COG1058	Belongs to the CinA family
BC359_07195	COG1692	metallophosphoesterase
BC359_07200	COG2359	stage V sporulation protein S
BC359_07210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BC359_07210	COG0674	pyruvate-flavodoxin oxidoreductase activity
BC359_07215	COG1013	pyruvate-flavodoxin oxidoreductase activity
BC359_07225	COG0156	8-amino-7-oxononanoate synthase activity
BC359_07230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC359_07235	COG4550	Control of competence regulator ComK, YlbF/YmcA
BC359_07245	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BC359_07260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BC359_07270	COG0464	growth
BC359_07275	COG2860	membrane
BC359_07280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC359_07285	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BC359_07290	COG0789	Transcriptional regulator
BC359_07295	COG0174	glutamine synthetase
BC359_07300	COG0582	viral genome integration into host DNA
BC359_07305	COG2856	Zn peptidase
BC359_07355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC359_07360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC359_07375	COG0583	DNA-binding transcription factor activity
BC359_07380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_07385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC359_07390	COG1587	Uroporphyrinogen-III synthase
BC359_07395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC359_07400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC359_07415	COG1982	Orn Lys Arg decarboxylase major
BC359_07425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC359_07425	COG1017	nitric oxide dioxygenase activity
BC359_07430	COG1959	2 iron, 2 sulfur cluster binding
BC359_07445	COG3316	Transposase and inactivated derivatives
BC359_07450	COG1271	oxidase subunit
BC359_07455	COG1294	oxidase, subunit
BC359_07460	COG1271	oxidase subunit
BC359_07465	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BC359_07505	COG0531	amino acid
BC359_07510	COG1846	Transcriptional regulator
BC359_07515	COG0456	acetyltransferase
BC359_07525	COG1078	dGTPase activity
BC359_07525	COG1078	dGTPase activity
BC359_07530	COG0662	Cupin 2, conserved barrel domain protein
BC359_07535	COG2814	Major facilitator Superfamily
BC359_07545	COG0531	amino acid
BC359_07565	COG0659	secondary active sulfate transmembrane transporter activity
BC359_07565	COG0659	secondary active sulfate transmembrane transporter activity
BC359_07575	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BC359_07595	COG3409	Peptidoglycan-binding domain 1 protein
BC359_07595	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC359_07605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BC359_07615	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC359_07620	COG4224	UPF0291 protein
BC359_07635	COG3763	UPF0154 protein
BC359_07640	COG1132	(ABC) transporter
BC359_07645	COG1132	(ABC) transporter
BC359_07650	COG0785	Cytochrome C biogenesis protein
BC359_07655	COG2201	protein-glutamate methylesterase activity
BC359_07660	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BC359_07675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC359_07690	COG1012	belongs to the aldehyde dehydrogenase family
BC359_07695	COG1966	Carbon starvation protein
BC359_07705	COG5002	protein histidine kinase activity
BC359_07715	COG3142	Participates in the control of copper homeostasis
BC359_07725	COG0076	glutamate decarboxylase activity
BC359_07760	COG0788	formyltetrahydrofolate deformylase activity
BC359_07765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BC359_07770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BC359_07775	COG0204	Acyl-transferase
BC359_07780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC359_07790	COG1307	EDD domain protein, DegV family
BC359_07795	COG5002	protein histidine kinase activity
BC359_07800	COG1999	signal sequence binding
BC359_07805	COG2755	lipolytic protein G-D-S-L family
BC359_07825	COG4191	Histidine kinase
BC359_07835	COG0577	efflux transmembrane transporter activity
BC359_07840	COG1136	(ABC) transporter
BC359_07845	COG2205	protein histidine kinase activity
BC359_07850	COG0745	RESPONSE REGULATOR receiver
BC359_07855	COG1301	dicarboxylic acid transport
BC359_07865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC359_07870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC359_07880	COG1509	lysine 2,3-aminomutase activity
BC359_07895	COG3594	Acyltransferase
BC359_07920	COG0515	serine threonine protein kinase
BC359_07925	COG4326	sporulation control protein
BC359_07930	COG0671	phosphoesterase, PA-phosphatase related
BC359_07940	COG0813	purine-nucleoside phosphorylase activity
BC359_07945	COG0659	secondary active sulfate transmembrane transporter activity
BC359_07955	COG0772	Belongs to the SEDS family
BC359_07975	COG2190	(PTS) system
BC359_07980	COG3711	transcriptional antiterminator
BC359_07985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_07985	COG1263	PTS System
BC359_08010	COG0456	acetyltransferase
BC359_08015	COG4555	ABC transporter
BC359_08025	COG0584	glycerophosphoryl diester phosphodiesterase
BC359_08040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_08085	COG0791	NLP P60 protein
BC359_08085	COG1388	LysM domain
BC359_08090	COG0205	6-phosphofructokinase activity
BC359_08095	COG0589	response to stress
BC359_08100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BC359_08110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BC359_08120	COG1253	flavin adenine dinucleotide binding
BC359_08125	COG2340	Cysteine-rich secretory protein family
BC359_08130	COG0668	transmembrane transport
BC359_08135	COG2323	membrane
BC359_08140	COG1280	lysine exporter protein (LysE YggA)
BC359_08145	COG2514	catechol 2,3-dioxygenase activity
BC359_08160	COG2205	protein histidine kinase activity
BC359_08165	COG1609	Transcriptional regulator
BC359_08185	COG0395	ABC-type sugar transport system, permease component
BC359_08190	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BC359_08195	COG1737	Transcriptional regulator
BC359_08200	COG1263	PTS System
BC359_08200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_08210	COG3876	Protein conserved in bacteria
BC359_08215	COG1472	Belongs to the glycosyl hydrolase 3 family
BC359_08225	COG1309	transcriptional regulator
BC359_08230	COG2814	Major facilitator Superfamily
BC359_08255	COG0517	IMP dehydrogenase activity
BC359_08255	COG1125	glycine betaine transport
BC359_08260	COG1174	glycine betaine transport
BC359_08270	COG1316	TRANSCRIPTIONal
BC359_08280	COG0006	proline dipeptidase activity
BC359_08305	COG0789	Transcriptional regulator
BC359_08310	COG1607	acyl-coa hydrolase
BC359_08315	COG2247	cell wall binding repeat
BC359_08315	COG2385	sporulation resulting in formation of a cellular spore
BC359_08320	COG2770	Histidine kinase
BC359_08320	COG2205	protein histidine kinase activity
BC359_08325	COG0745	RESPONSE REGULATOR receiver
BC359_08330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC359_08340	COG1522	sequence-specific DNA binding
BC359_08345	COG0569	domain protein
BC359_08350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC359_08360	COG1404	Belongs to the peptidase S8 family
BC359_08365	COG0840	transmembrane signaling receptor activity
BC359_08370	COG0791	NLP P60 protein
BC359_08370	COG1388	LysM domain
BC359_08395	COG1216	Glycosyl transferase, family 2
BC359_08400	COG2259	Doxx family
BC359_08415	COG4980	gas vesicle protein
BC359_08425	COG1764	response to oxidative stress
BC359_08440	COG0454	-acetyltransferase
BC359_08445	COG2814	Major facilitator Superfamily
BC359_08455	COG4195	phage-related replication protein
BC359_08460	COG3226	Transcriptional regulator
BC359_08470	COG0861	Integral membrane protein TerC family
BC359_08475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BC359_08475	COG2755	lipolytic protein G-D-S-L family
BC359_08485	COG0110	maltose O-acetyltransferase activity
BC359_08490	COG0531	amino acid
BC359_08495	COG0561	phosphatase activity
BC359_08525	COG1937	Protein conserved in bacteria
BC359_08530	COG2608	mercury ion transmembrane transporter activity
BC359_08535	COG2217	Heavy metal translocating P-type atpase
BC359_08540	COG2312	Erythromycin esterase
BC359_08545	COG0346	lactoylglutathione lyase activity
BC359_08555	COG4948	Mandelate Racemase Muconate Lactonizing
BC359_08585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_08590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC359_08610	COG4335	DNA alkylation repair
BC359_08615	COG1187	pseudouridine synthase activity
BC359_08620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_08625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_08630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC359_08635	COG1120	ATPase activity
BC359_08650	COG1114	Component of the transport system for branched-chain amino acids
BC359_08660	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BC359_08670	COG0640	Transcriptional regulator
BC359_08680	COG0405	Gamma-glutamyltransferase
BC359_08685	COG1253	flavin adenine dinucleotide binding
BC359_08690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BC359_08705	COG0024	Methionine aminopeptidase
BC359_08715	COG0346	lactoylglutathione lyase activity
BC359_08720	COG2807	transmembrane transport
BC359_08740	COG2814	Major facilitator Superfamily
BC359_08750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BC359_08755	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC359_08760	COG3695	enzyme binding
BC359_08785	COG1609	Transcriptional regulator
BC359_08790	COG2211	Major facilitator Superfamily
BC359_08810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BC359_08835	COG2244	polysaccharide biosynthetic process
BC359_08845	COG0604	alcohol dehydrogenase
BC359_08845	COG3321	synthase
BC359_08850	COG1979	alcohol dehydrogenase
BC359_08860	COG1309	transcriptional regulator
BC359_08865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_08875	COG1846	Transcriptional regulator
BC359_08880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BC359_08900	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_08905	COG0371	Dehydrogenase
BC359_08920	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BC359_08935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BC359_08940	COG2186	Transcriptional regulator
BC359_08970	COG1278	Cold shock
BC359_08975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BC359_08980	COG2076	Multidrug Resistance protein
BC359_08990	COG4195	phage-related replication protein
BC359_09005	COG1742	UPF0060 membrane protein
BC359_09010	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BC359_09025	COG0456	acetyltransferase
BC359_09030	COG1464	Belongs to the NlpA lipoprotein family
BC359_09035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC359_09040	COG2011	ABC-type metal ion transport system permease component
BC359_09045	COG0039	L-malate dehydrogenase activity
BC359_09075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BC359_09080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BC359_09100	COG5566	PFAM Mor transcription activator
BC359_09125	COG2130	NADP-dependent
BC359_09145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_09150	COG0730	response to heat
BC359_09155	COG3764	Sortase (surface protein transpeptidase)
BC359_09170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BC359_09185	COG1937	Protein conserved in bacteria
BC359_09195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BC359_09200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC359_09210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BC359_09235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_09240	COG1316	TRANSCRIPTIONal
BC359_09260	COG2814	Major facilitator Superfamily
BC359_09265	COG1309	transcriptional regulator
BC359_09270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC359_09300	COG0583	DNA-binding transcription factor activity
BC359_09305	COG0372	Belongs to the citrate synthase family
BC359_09335	COG1597	lipid kinase activity
BC359_09355	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BC359_09370	COG2318	DinB family
BC359_09375	COG0733	neurotransmitter:sodium symporter activity
BC359_09380	COG2002	toxin-antitoxin pair type II binding
BC359_09390	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC359_09395	COG3103	Sh3 type 3 domain protein
BC359_09395	COG4991	sh3 domain protein
BC359_09395	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_09400	COG4991	sh3 domain protein
BC359_09400	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_09400	COG3103	Sh3 type 3 domain protein
BC359_09425	COG0640	Transcriptional regulator
BC359_09440	COG0681	Belongs to the peptidase S26 family
BC359_09445	COG1902	pentaerythritol trinitrate reductase activity
BC359_09450	COG0730	response to heat
BC359_09475	COG0754	glutathionylspermidine amidase activity
BC359_09495	COG0733	neurotransmitter:sodium symporter activity
BC359_09505	COG0753	catalase activity
BC359_09510	COG1388	LysM domain
BC359_09510	COG0791	NLP P60 protein
BC359_09515	COG0011	TIGRFAM Protein of
BC359_09520	COG2508	Transcriptional regulator
BC359_09535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC359_09545	COG2059	Chromate
BC359_09550	COG2059	Chromate
BC359_09555	COG1605	Chorismate mutase
BC359_09555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC359_09565	COG0287	Prephenate dehydrogenase
BC359_09580	COG0723	plastoquinol--plastocyanin reductase activity
BC359_09580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC359_09595	COG0516	GMP reductase activity
BC359_09595	COG0517	IMP dehydrogenase activity
BC359_09605	COG1695	Transcriptional regulator
BC359_09610	COG2059	Chromate
BC359_09620	COG1253	flavin adenine dinucleotide binding
BC359_09625	COG3878	Protein conserved in bacteria
BC359_09630	COG5577	PFAM Coat F domain
BC359_09640	COG0783	Belongs to the Dps family
BC359_09675	COG1132	(ABC) transporter
BC359_09690	COG5002	protein histidine kinase activity
BC359_09695	COG0745	RESPONSE REGULATOR receiver
BC359_09700	COG1469	GTP cyclohydrolase I activity
BC359_09705	COG2244	polysaccharide biosynthetic process
BC359_09710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC359_09715	COG0400	carboxylic ester hydrolase activity
BC359_09730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BC359_09735	COG0778	Nitroreductase
BC359_09740	COG3584	3D domain protein
BC359_09740	COG1388	LysM domain
BC359_09750	COG0559	Belongs to the binding-protein-dependent transport system permease family
BC359_09760	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BC359_09770	COG0831	urea catabolic process
BC359_09775	COG0832	Belongs to the urease beta subunit family
BC359_09820	COG1233	COG1233 Phytoene dehydrogenase and related
BC359_09830	COG1301	dicarboxylic acid transport
BC359_09835	COG2404	hydrolase activity, acting on ester bonds
BC359_09840	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_09845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BC359_09850	COG1733	regulation of RNA biosynthetic process
BC359_09865	COG4145	pantothenate transmembrane transporter activity
BC359_09870	COG1492	cobalamin metabolic process
BC359_09875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_09880	COG4604	ABC transporter, ATP-binding protein
BC359_09895	COG1960	acyl-CoA dehydrogenase activity
BC359_09910	COG1215	transferase activity, transferring glycosyl groups
BC359_09920	COG1086	Polysaccharide biosynthesis protein
BC359_09935	COG2182	Extracellular solute-binding protein
BC359_09940	COG1175	transmembrane transport
BC359_09945	COG3833	ABC-type maltose transport systems, permease component
BC359_09960	COG0438	transferase activity, transferring glycosyl groups
BC359_09965	COG1216	Glycosyl transferase, family 2
BC359_09975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BC359_09975	COG0456	acetyltransferase
BC359_10020	COG2311	Membrane
BC359_10030	COG1764	response to oxidative stress
BC359_10035	COG0567	Dehydrogenase, E1 component
BC359_10040	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC359_10060	COG4682	membrane
BC359_10070	COG1301	dicarboxylic acid transport
BC359_10090	COG2390	Transcriptional regulator
BC359_10100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BC359_10105	COG0295	cytidine deaminase activity
BC359_10110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC359_10120	COG2309	aminopeptidase activity
BC359_10160	COG1114	Component of the transport system for branched-chain amino acids
BC359_10170	COG1525	nuclease
BC359_10195	COG0673	inositol 2-dehydrogenase activity
BC359_10200	COG0673	inositol 2-dehydrogenase activity
BC359_10205	COG1082	Xylose isomerase domain protein TIM barrel
BC359_10210	COG2814	Major facilitator Superfamily
BC359_10230	COG0656	L-ascorbic acid biosynthetic process
BC359_10235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_10250	COG0156	8-amino-7-oxononanoate synthase activity
BC359_10255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BC359_10295	COG0444	Belongs to the ABC transporter superfamily
BC359_10300	COG4608	Belongs to the ABC transporter superfamily
BC359_10310	COG1396	sequence-specific DNA binding
BC359_10325	COG1280	lysine exporter protein (LysE YggA)
BC359_10330	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC359_10370	COG0697	spore germination
BC359_10390	COG2814	Major facilitator Superfamily
BC359_10390	COG0477	Major facilitator Superfamily
BC359_10400	COG2391	methyltransferase activity
BC359_10410	COG2814	Major facilitator Superfamily
BC359_10445	COG0346	lactoylglutathione lyase activity
BC359_10460	COG2323	membrane
BC359_10500	COG2814	Major facilitator Superfamily
BC359_10505	COG0583	DNA-binding transcription factor activity
BC359_10525	COG2207	Transcriptional regulator
BC359_10525	COG1917	Cupin 2, conserved barrel domain protein
BC359_10560	COG4319	ketosteroid isomerase
BC359_10585	COG1263	PTS System
BC359_10585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_10610	COG0697	spore germination
BC359_10615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_10650	COG0561	phosphatase activity
BC359_10670	COG0456	acetyltransferase
BC359_10685	COG0456	acetyltransferase
BC359_10705	COG0656	L-ascorbic acid biosynthetic process
BC359_10750	COG5444	nuclease activity
BC359_10825	COG5444	nuclease activity
BC359_10875	COG0617	tRNA 3'-terminal CCA addition
BC359_10900	COG1937	Protein conserved in bacteria
BC359_10905	COG0425	Belongs to the sulfur carrier protein TusA family
BC359_10910	COG2210	Belongs to the sulfur carrier protein TusA family
BC359_10915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_10920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_10920	COG0425	Belongs to the sulfur carrier protein TusA family
BC359_10925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_10925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_10930	COG0425	Belongs to the sulfur carrier protein TusA family
BC359_10935	COG0730	response to heat
BC359_10940	COG0109	protoheme IX farnesyltransferase activity
BC359_10945	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_10950	COG1309	transcriptional regulator
BC359_10955	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC359_10965	COG1960	acyl-CoA dehydrogenase activity
BC359_11000	COG0393	Putative heavy-metal-binding
BC359_11015	COG3583	domain protein
BC359_11015	COG3584	3D domain protein
BC359_11025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_11040	COG2723	6-phospho-beta-galactosidase activity
BC359_11060	COG0579	oxidoreductase
BC359_11075	COG2329	Antibiotic biosynthesis monooxygenase
BC359_11080	COG1278	Cold shock
BC359_11095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC359_11100	COG0583	DNA-binding transcription factor activity
BC359_11205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC359_11220	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_11230	COG3973	AAA domain
BC359_11235	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_11240	COG3773	Cell wall hydrolase
BC359_11300	COG2204	response regulator
BC359_11305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC359_11315	COG1595	DNA-templated transcription, initiation
BC359_11320	COG0326	Molecular chaperone. Has ATPase activity
BC359_11355	COG2124	cytochrome p450
BC359_11360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BC359_11370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC359_11375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_11395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC359_11400	COG2720	vancomycin resistance protein
BC359_11405	COG1846	Transcriptional regulator
BC359_11410	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_11425	COG0702	epimerase
BC359_11430	COG0494	nUDIX hydrolase
BC359_11445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BC359_11450	COG0456	acetyltransferase
BC359_11455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC359_11455	COG3153	acetyltransferase
BC359_11465	COG0791	NLP P60 protein
BC359_11465	COG3883	PFAM NLP P60 protein
BC359_11470	COG1587	Uroporphyrinogen-III synthase
BC359_11475	COG1414	Transcriptional regulator
BC359_11480	COG0439	Biotin carboxylase
BC359_11485	COG0511	ligase activity, forming carbon-carbon bonds
BC359_11490	COG1984	allophanate hydrolase subunit 2
BC359_11495	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC359_11500	COG4336	lyase activity
BC359_11505	COG1914	H( )-stimulated, divalent metal cation uptake system
BC359_11510	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BC359_11515	COG0791	NLP P60 protein
BC359_11535	COG2197	response regulator
BC359_11540	COG2203	Gaf domain
BC359_11540	COG4585	Histidine kinase
BC359_11555	COG0129	dihydroxy-acid dehydratase activity
BC359_11560	COG1227	inorganic diphosphatase activity
BC359_11575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC359_11585	COG2233	PERMEase
BC359_11600	COG1247	-acetyltransferase
BC359_11625	COG4974	Belongs to the 'phage' integrase family
BC359_11650	COG1335	isochorismatase
BC359_11660	COG3403	YqcI/YcgG family
BC359_11665	COG2267	carboxylic ester hydrolase activity
BC359_11675	COG0187	DNA topoisomerase II activity
BC359_11680	COG1832	CoA-binding protein
BC359_11685	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BC359_11690	COG4841	protein insertion into membrane
BC359_11695	COG0824	Thioesterase
BC359_11715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_11720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BC359_11745	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BC359_11780	COG2814	Major facilitator Superfamily
BC359_11785	COG1295	ribonuclease BN
BC359_11795	COG2814	Major facilitator Superfamily
BC359_11800	COG0789	Transcriptional regulator
BC359_11805	COG0659	secondary active sulfate transmembrane transporter activity
BC359_11825	COG1247	-acetyltransferase
BC359_11845	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_11850	COG5002	protein histidine kinase activity
BC359_11870	COG0004	ammonium transporteR
BC359_11885	COG1252	NADH dehydrogenase
BC359_11900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC359_11920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC359_11935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC359_11940	COG0438	transferase activity, transferring glycosyl groups
BC359_11955	COG0438	transferase activity, transferring glycosyl groups
BC359_11960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC359_11995	COG0456	acetyltransferase
BC359_12000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC359_12010	COG0586	Pfam SNARE associated Golgi protein
BC359_12015	COG0534	Mate efflux family protein
BC359_12025	COG1164	Oligoendopeptidase f
BC359_12030	COG0708	Exodeoxyribonuclease III
BC359_12035	COG0737	Belongs to the 5'-nucleotidase family
BC359_12050	COG1295	ribonuclease BN
BC359_12055	COG1834	amidinotransferase
BC359_12060	COG2409	Drug exporters of the RND superfamily
BC359_12085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BC359_12090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BC359_12095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC359_12100	COG2201	protein-glutamate methylesterase activity
BC359_12120	COG1388	LysM domain
BC359_12120	COG3584	3D domain protein
BC359_12130	COG1846	Transcriptional regulator
BC359_12135	COG1764	response to oxidative stress
BC359_12160	COG1131	(ABC) transporter
BC359_12165	COG1725	Transcriptional regulator
BC359_12170	COG0583	DNA-binding transcription factor activity
BC359_12175	COG1120	ATPase activity
BC359_12185	COG3546	catalase activity
BC359_12190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC359_12195	COG1575	Belongs to the MenA family. Type 1 subfamily
BC359_12215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC359_12225	COG0551	DNA topoisomerase type I activity
BC359_12225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC359_12250	COG1609	Transcriptional regulator
BC359_12270	COG1131	(ABC) transporter
BC359_12280	COG0488	(ABC) transporter
BC359_12290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC359_12295	COG2378	regulation of single-species biofilm formation
BC359_12305	COG2223	nitrite transmembrane transporter activity
BC359_12310	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_12315	COG3835	regulator
BC359_12325	COG0247	lactate metabolic process
BC359_12340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BC359_12345	COG1335	isochorismatase
BC359_12350	COG0494	nUDIX hydrolase
BC359_12360	COG1132	(ABC) transporter
BC359_12395	COG0297	glycogen (starch) synthase activity
BC359_12410	COG1396	sequence-specific DNA binding
BC359_12415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BC359_12420	COG0110	maltose O-acetyltransferase activity
BC359_12425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC359_12435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC359_12445	COG1215	transferase activity, transferring glycosyl groups
BC359_12450	COG0438	transferase activity, transferring glycosyl groups
BC359_12455	COG0438	transferase activity, transferring glycosyl groups
BC359_12460	COG1086	Polysaccharide biosynthesis protein
BC359_12465	COG0489	protein tyrosine kinase activity
BC359_12470	COG3944	biosynthesis protein
BC359_12485	COG2720	vancomycin resistance protein
BC359_12490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC359_12515	COG1657	PFAM Prenyltransferase squalene oxidase
BC359_12520	COG1119	ATPase activity
BC359_12530	COG2207	Transcriptional regulator
BC359_12545	COG4548	von Willebrand factor, type A
BC359_12550	COG0714	Associated with various cellular activities
BC359_12560	COG1595	DNA-templated transcription, initiation
BC359_12580	COG3871	stress protein (general stress protein 26)
BC359_12585	COG0352	thiamine-phosphate diphosphorylase activity
BC359_12590	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BC359_12605	COG2094	Belongs to the DNA glycosylase MPG family
BC359_12615	COG0673	inositol 2-dehydrogenase activity
BC359_12620	COG0673	inositol 2-dehydrogenase activity
BC359_12635	COG3773	Cell wall hydrolase
BC359_12640	COG0733	neurotransmitter:sodium symporter activity
BC359_12660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC359_12665	COG1012	belongs to the aldehyde dehydrogenase family
BC359_12675	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_12695	COG2032	superoxide dismutase activity
BC359_12705	COG0527	aspartate kinase activity
BC359_12710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC359_12710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC359_12710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC359_12715	COG1105	Belongs to the carbohydrate kinase PfkB family
BC359_12720	COG1349	DNA-binding transcription factor activity
BC359_12730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_12740	COG2323	membrane
BC359_12745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_12750	COG2323	membrane
BC359_12765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC359_12795	COG5002	protein histidine kinase activity
BC359_12805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC359_12810	COG2246	polysaccharide biosynthetic process
BC359_12815	COG0463	Glycosyl transferase, family 2
BC359_12825	COG3546	catalase activity
BC359_12845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BC359_12850	COG0628	permease
BC359_12855	COG1012	belongs to the aldehyde dehydrogenase family
BC359_12875	COG0493	'glutamate synthase
BC359_12880	COG0070	glutamate synthase
BC359_12880	COG0067	glutamate synthase
BC359_12880	COG0069	glutamate synthase activity
BC359_12885	COG0583	DNA-binding transcription factor activity
BC359_12900	COG1278	Cold shock
BC359_12905	COG3830	Belongs to the UPF0237 family
BC359_12910	COG2848	UPF0210 protein
BC359_12925	COG3402	PFAM membrane-flanked domain
BC359_12930	COG0281	malic enzyme
BC359_12935	COG1027	Aspartate ammonia-lyase
BC359_12940	COG1611	Belongs to the LOG family
BC359_12960	COG0281	malic enzyme
BC359_12975	COG3104	oligopeptide transport
BC359_12980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC359_12985	COG5002	protein histidine kinase activity
BC359_12995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC359_13005	COG0833	amino acid
BC359_13010	COG1757	Na H antiporter
BC359_13015	COG3361	conserved protein (COG2071)
BC359_13025	COG1360	Flagellar Motor Protein
BC359_13030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BC359_13035	COG2112	serine threonine protein kinase
BC359_13040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BC359_13040	COG2124	cytochrome p450
BC359_13045	COG1012	belongs to the aldehyde dehydrogenase family
BC359_13050	COG1823	symporter activity
BC359_13060	COG2234	aminopeptidase activity
BC359_13085	COG3853	Toxic anion resistance protein (TelA)
BC359_13095	COG1368	sulfuric ester hydrolase activity
BC359_13105	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_13115	COG2002	toxin-antitoxin pair type II binding
BC359_13140	COG1595	DNA-templated transcription, initiation
BC359_13145	COG3011	Protein conserved in bacteria
BC359_13150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC359_13160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC359_13165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC359_13180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC359_13195	COG2962	Rard protein
BC359_13200	COG2096	Adenosyltransferase
BC359_13210	COG0588	phosphoglycerate mutase activity
BC359_13215	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BC359_13230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BC359_13240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC359_13250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_13265	COG2521	methyltransferase
BC359_13265	COG2136	Putative SAM-dependent methyltransferase
BC359_13280	COG1413	lyase activity
BC359_13285	COG0488	(ABC) transporter
BC359_13290	COG1418	mRNA catabolic process
BC359_13295	COG0386	Belongs to the glutathione peroxidase family
BC359_13310	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BC359_13320	COG2226	methyltransferase
BC359_13335	COG1940	carbohydrate kinase activity
BC359_13340	COG2182	Extracellular solute-binding protein
BC359_13355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC359_13355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC359_13360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC359_13360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC359_13365	COG2814	Major facilitator Superfamily
BC359_13375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC359_13395	COG1819	glycosyl
BC359_13450	COG0534	Mate efflux family protein
BC359_13455	COG4608	Belongs to the ABC transporter superfamily
BC359_13460	COG0444	Belongs to the ABC transporter superfamily
BC359_13470	COG0601	transmembrane transport
BC359_13475	COG0747	negative chemotaxis
BC359_13500	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_13505	COG0561	phosphatase activity
BC359_13520	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC359_13525	COG0640	Transcriptional regulator
BC359_13535	COG0640	Transcriptional regulator
BC359_13540	COG0346	lactoylglutathione lyase activity
BC359_13550	COG0655	NAD(P)H dehydrogenase (quinone) activity
BC359_13555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC359_13565	COG2271	Major facilitator Superfamily
BC359_13570	COG1388	LysM domain
BC359_13575	COG0745	RESPONSE REGULATOR receiver
BC359_13580	COG5002	protein histidine kinase activity
BC359_13585	COG0596	Alpha beta hydrolase
BC359_13600	COG2197	response regulator
BC359_13605	COG4585	Histidine kinase
BC359_13610	COG3239	Fatty acid desaturase
BC359_13615	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC359_13620	COG0701	Predicted permease
BC359_13635	COG4608	Belongs to the ABC transporter superfamily
BC359_13640	COG0791	NLP P60 protein
BC359_13650	COG4166	transmembrane transport
BC359_13655	COG0444	Belongs to the ABC transporter superfamily
BC359_13660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC359_13665	COG0601	transmembrane transport
BC359_13670	COG2362	D-Aminopeptidase
BC359_13695	COG2814	Major facilitator Superfamily
BC359_13700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC359_13720	COG0328	RNA-DNA hybrid ribonuclease activity
BC359_13725	COG0328	RNA-DNA hybrid ribonuclease activity
BC359_13755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC359_13760	COG1755	Isoprenylcysteine carboxyl methyltransferase
BC359_13775	COG2233	PERMEase
BC359_13780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC359_13785	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BC359_13790	COG1199	ATP-dependent helicase activity
BC359_13805	COG0116	Belongs to the methyltransferase superfamily
BC359_13810	COG0366	Alpha amylase catalytic
BC359_13815	COG2197	response regulator
BC359_13820	COG4585	Histidine kinase
BC359_13845	COG3599	regulation of cell shape
BC359_13850	COG4474	Belongs to the UPF0398 family
BC359_13860	COG3359	exonuclease
BC359_13865	COG1205	dead DEAH box helicase
BC359_13865	COG1111	helicase
BC359_13880	COG1331	Highly conserved protein containing a thioredoxin domain
BC359_13895	COG4607	ABC-type enterochelin transport system periplasmic component
BC359_13900	COG4604	ABC transporter, ATP-binding protein
BC359_13905	COG4605	iron ion homeostasis
BC359_13910	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_13945	COG1278	Cold shock
BC359_13955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_13970	COG0626	cystathionine gamma-synthase activity
BC359_13975	COG0626	cystathionine gamma-synthase activity
BC359_13980	COG5337	Spore coat protein CotH
BC359_14015	COG3331	DNA recombination
BC359_14030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BC359_14035	COG3935	DnaD domain protein
BC359_14040	COG0017	Asparaginyl-tRNA synthetase
BC359_14045	COG0436	Aminotransferase
BC359_14065	COG1199	ATP-dependent helicase activity
BC359_14065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BC359_14070	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BC359_14075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BC359_14090	COG0617	tRNA 3'-terminal CCA addition
BC359_14095	COG0438	transferase activity, transferring glycosyl groups
BC359_14100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC359_14105	COG1803	Methylglyoxal synthase
BC359_14110	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BC359_14115	COG1694	Mazg nucleotide pyrophosphohydrolase
BC359_14120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_14125	COG2738	Putative neutral zinc metallopeptidase
BC359_14135	COG2340	Cysteine-rich secretory protein family
BC359_14140	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BC359_14150	COG3336	cytochrome c oxidase
BC359_14180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BC359_14185	COG0772	Belongs to the SEDS family
BC359_14190	COG4838	Belongs to the UPF0358 family
BC359_14195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC359_14200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BC359_14215	COG4896	Protein conserved in bacteria
BC359_14240	COG0483	inositol monophosphate 1-phosphatase activity
BC359_14250	COG4493	Belongs to the UPF0637 family
BC359_14255	COG4476	Belongs to the UPF0223 family
BC359_14260	COG1982	Orn Lys Arg decarboxylase major
BC359_14270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC359_14280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC359_14285	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC359_14290	COG0022	dehydrogenase e1 component
BC359_14305	COG0242	peptide deformylase activity
BC359_14310	COG0561	phosphatase activity
BC359_14320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC359_14335	COG1131	(ABC) transporter
BC359_14340	COG2197	response regulator
BC359_14345	COG4585	Histidine kinase
BC359_14350	COG0569	domain protein
BC359_14355	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC359_14360	COG0450	alkyl hydroperoxide reductase
BC359_14365	COG0668	transmembrane transport
BC359_14370	COG1473	amidohydrolase
BC359_14375	COG2171	N-acyltransferase activity
BC359_14380	COG0583	DNA-binding transcription factor activity
BC359_14385	COG4703	Protein of unknown function (DUF1797)
BC359_14400	COG2200	EAL domain
BC359_14405	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_14410	COG1408	metallophosphoesterase
BC359_14425	COG0248	Ppx GppA phosphatase
BC359_14430	COG1376	ErfK ybiS ycfS ynhG family protein
BC359_14440	COG4975	Glucose uptake
BC359_14450	COG0835	chemotaxis
BC359_14450	COG0784	Response regulator, receiver
BC359_14465	COG0436	Aminotransferase
BC359_14480	COG2084	Dehydrogenase
BC359_14485	COG0778	Nitroreductase
BC359_14500	COG0583	DNA-binding transcription factor activity
BC359_14505	COG1733	regulation of RNA biosynthetic process
BC359_14510	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BC359_14515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BC359_14525	COG1346	cytolysis
BC359_14550	COG2190	(PTS) system
BC359_14550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_14550	COG1263	PTS System
BC359_14555	COG3711	transcriptional antiterminator
BC359_14565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BC359_14570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC359_14570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC359_14575	COG0307	riboflavin synthase, alpha
BC359_14580	COG3949	Membrane
BC359_14585	COG4989	oxidoreductase activity
BC359_14590	COG0646	methionine synthase
BC359_14590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BC359_14595	COG0646	methionine synthase
BC359_14595	COG1410	methionine synthase
BC359_14600	COG1966	Carbon starvation protein
BC359_14630	COG5506	Protein of unknown function (DUF1694)
BC359_14635	COG3773	Cell wall hydrolase
BC359_14655	COG4873	Protein conserved in bacteria
BC359_14660	COG0702	epimerase
BC359_14665	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BC359_14670	COG0602	queuosine metabolic process
BC359_14675	COG0720	synthase
BC359_14680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BC359_14685	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BC359_14690	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BC359_14710	COG0697	spore germination
BC359_14715	COG0300	oxidoreductase activity
BC359_14735	COG0542	response to heat
BC359_14750	COG1846	Transcriptional regulator
BC359_14775	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC359_14780	COG1129	ABC transporter
BC359_14800	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BC359_14805	COG1850	ribulose-bisphosphate carboxylase activity
BC359_14810	COG0436	Aminotransferase
BC359_14815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC359_14820	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BC359_14825	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BC359_14835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC359_14850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BC359_14855	COG1032	radical SAM domain protein
BC359_14860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC359_14895	COG0861	Integral membrane protein TerC family
BC359_14910	COG3279	Response regulator of the LytR AlgR family
BC359_14920	COG1785	Belongs to the alkaline phosphatase family
BC359_14940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC359_14940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC359_14945	COG0477	Major facilitator Superfamily
BC359_14950	COG1846	Transcriptional regulator
BC359_14970	COG2252	PERMEase
BC359_15020	COG0346	lactoylglutathione lyase activity
BC359_15030	COG1253	flavin adenine dinucleotide binding
BC359_15035	COG0737	Belongs to the 5'-nucleotidase family
BC359_15035	COG4085	toxin activity
BC359_15035	COG1525	nuclease
BC359_15040	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BC359_15045	COG4988	ABC transporter
BC359_15050	COG1294	oxidase, subunit
BC359_15055	COG1271	oxidase subunit
BC359_15065	COG1063	alcohol dehydrogenase
BC359_15085	COG1131	(ABC) transporter
BC359_15110	COG1263	PTS System
BC359_15110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_15110	COG2190	(PTS) system
BC359_15115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BC359_15120	COG0363	glucosamine-6-phosphate deaminase activity
BC359_15160	COG0561	phosphatase activity
BC359_15165	COG1609	Transcriptional regulator
BC359_15170	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BC359_15210	COG4948	Mandelate Racemase Muconate Lactonizing
BC359_15220	COG1737	Transcriptional regulator
BC359_15225	COG1473	amidohydrolase
BC359_15245	COG0861	Integral membrane protein TerC family
BC359_15330	COG5444	nuclease activity
BC359_15345	COG1959	2 iron, 2 sulfur cluster binding
BC359_15350	COG0702	epimerase
BC359_15360	COG5577	PFAM Coat F domain
BC359_15365	COG1063	alcohol dehydrogenase
BC359_15375	COG5577	PFAM Coat F domain
BC359_15415	COG0489	protein tyrosine kinase activity
BC359_15420	COG3944	biosynthesis protein
BC359_15425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC359_15430	COG1482	cell wall glycoprotein biosynthetic process
BC359_15445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BC359_15470	COG0438	transferase activity, transferring glycosyl groups
BC359_15480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC359_15485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC359_15490	COG4464	protein tyrosine phosphatase activity
BC359_15515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC359_15550	COG1309	transcriptional regulator
BC359_15560	COG0840	transmembrane signaling receptor activity
BC359_15565	COG0791	NLP P60 protein
BC359_15575	COG5002	protein histidine kinase activity
BC359_15575	COG5001	Diguanylate cyclase
BC359_15575	COG3447	MASE1 domain protein
BC359_15585	COG1472	Belongs to the glycosyl hydrolase 3 family
BC359_15590	COG4640	response to antibiotic
BC359_15600	COG4640	response to antibiotic
BC359_15615	COG4842	Belongs to the WXG100 family
BC359_15620	COG0753	catalase activity
BC359_15630	COG3706	GGDEF domain
BC359_15640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BC359_15645	COG3300	MHYT domain
BC359_15645	COG5001	Diguanylate cyclase
BC359_15655	COG1131	(ABC) transporter
BC359_15660	COG1725	Transcriptional regulator
BC359_15675	COG3718	enzyme involved in inositol metabolism
BC359_15700	COG0673	inositol 2-dehydrogenase activity
BC359_15705	COG2814	Major facilitator Superfamily
BC359_15710	COG0673	inositol 2-dehydrogenase activity
BC359_15725	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC359_15730	COG1129	ABC transporter
BC359_15745	COG0154	amidase activity
BC359_15755	COG1376	ErfK ybiS ycfS ynhG family protein
BC359_15770	COG0492	ferredoxin-NADP+ reductase activity
BC359_15785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BC359_15790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_15800	COG0628	permease
BC359_15860	COG2076	Multidrug Resistance protein
BC359_15865	COG2076	Multidrug Resistance protein
BC359_15870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC359_15890	COG0673	inositol 2-dehydrogenase activity
BC359_15910	COG1278	Cold shock
BC359_15915	COG0402	S-adenosylhomocysteine deaminase activity
BC359_15935	COG1272	protein, Hemolysin III
BC359_15945	COG0701	Predicted permease
BC359_15950	COG1914	H( )-stimulated, divalent metal cation uptake system
BC359_15955	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BC359_15960	COG1984	allophanate hydrolase subunit 2
BC359_15965	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC359_15970	COG2188	Transcriptional regulator
BC359_15975	COG0366	Alpha amylase catalytic
BC359_15985	COG0697	spore germination
BC359_15995	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BC359_16000	COG2252	PERMEase
BC359_16005	COG0402	S-adenosylhomocysteine deaminase activity
BC359_16035	COG0406	alpha-ribazole phosphatase activity
BC359_16045	COG0716	FMN binding
BC359_16065	COG5002	protein histidine kinase activity
BC359_16075	COG3706	GGDEF domain
BC359_16075	COG0745	RESPONSE REGULATOR receiver
BC359_16105	COG3584	3D domain protein
BC359_16105	COG3583	domain protein
BC359_16110	COG1879	ABC-type sugar transport system periplasmic component
BC359_16115	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC359_16120	COG1129	ABC transporter
BC359_16125	COG1869	D-ribose catabolic process
BC359_16130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC359_16135	COG1609	Transcriptional regulator
BC359_16140	COG0656	L-ascorbic acid biosynthetic process
BC359_16145	COG1414	Transcriptional regulator
BC359_16165	COG3162	membrane
BC359_16170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_16185	COG1733	regulation of RNA biosynthetic process
BC359_16190	COG1511	domain protein
BC359_16195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC359_16200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC359_16205	COG1116	anion transmembrane transporter activity
BC359_16210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC359_16215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC359_16220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC359_16230	COG2226	methyltransferase
BC359_16235	COG3180	Ammonia monooxygenase
BC359_16240	COG0583	DNA-binding transcription factor activity
BC359_16245	COG3181	Tripartite tricarboxylate transporter family receptor
BC359_16250	COG4565	transcriptional regulatory protein
BC359_16255	COG3290	protein histidine kinase activity
BC359_16260	COG2851	Citrate transporter
BC359_16280	COG3290	protein histidine kinase activity
BC359_16285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC359_16290	COG1301	dicarboxylic acid transport
BC359_16305	COG3773	Cell wall hydrolase
BC359_16320	COG0577	efflux transmembrane transporter activity
BC359_16325	COG1136	(ABC) transporter
BC359_16330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC359_16345	COG1607	acyl-coa hydrolase
BC359_16355	COG4297	protein containing double-stranded beta helix domain
BC359_16360	COG2814	Major facilitator Superfamily
BC359_16365	COG1733	regulation of RNA biosynthetic process
BC359_16370	COG4895	conserved protein (DUF2196)
BC359_16375	COG0584	glycerophosphoryl diester phosphodiesterase
BC359_16380	COG1620	l-lactate permease
BC359_16385	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC359_16390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BC359_16395	COG0277	FAD linked oxidase domain protein
BC359_16400	COG0247	lactate metabolic process
BC359_16410	COG2186	Transcriptional regulator
BC359_16420	COG1595	DNA-templated transcription, initiation
BC359_16435	COG0697	spore germination
BC359_16440	COG1802	Transcriptional regulator
BC359_16445	COG2202	Pas domain
BC359_16445	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_16455	COG2116	formate transmembrane transporter activity
BC359_16465	COG2146	nitrite reductase [NAD(P)H] activity
BC359_16470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC359_16475	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC359_16480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC359_16485	COG1121	(ABC) transporter
BC359_16540	COG0582	viral genome integration into host DNA
BC359_16545	COG0582	viral genome integration into host DNA
BC359_16570	COG1070	Carbohydrate kinase
BC359_16575	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC359_16580	COG1737	Transcriptional regulator
BC359_16590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC359_16600	COG2382	esterase
BC359_16610	COG2153	protein acetylation
BC359_16615	COG0697	spore germination
BC359_16620	COG0697	spore germination
BC359_16630	COG2323	membrane
BC359_16640	COG0210	DNA helicase
BC359_16695	COG0569	domain protein
BC359_16695	COG0475	glutathione-regulated potassium exporter activity
BC359_16700	COG2239	Acts as a magnesium transporter
BC359_16705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC359_16710	COG0564	pseudouridine synthase activity
BC359_16715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BC359_16720	COG2357	RelA SpoT domain protein
BC359_16730	COG4116	CYTH
BC359_16735	COG0741	lytic transglycosylase activity
BC359_16740	COG2346	COG2346, Truncated hemoglobins
BC359_16750	COG1164	Oligoendopeptidase f
BC359_16760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_16770	COG0861	Integral membrane protein TerC family
BC359_16775	COG1393	Belongs to the ArsC family
BC359_16790	COG0456	acetyltransferase
BC359_16795	COG4608	Belongs to the ABC transporter superfamily
BC359_16800	COG0444	Belongs to the ABC transporter superfamily
BC359_16805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC359_16810	COG0601	transmembrane transport
BC359_16815	COG4166	transmembrane transport
BC359_16820	COG0180	Tryptophanyl-tRNA synthetase
BC359_16830	COG5504	Zn-dependent protease
BC359_16835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC359_16840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC359_16860	COG2267	carboxylic ester hydrolase activity
BC359_16870	COG1874	Beta-galactosidase
BC359_16875	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BC359_16880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC359_16885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BC359_16910	COG0542	response to heat
BC359_16925	COG0702	epimerase
BC359_16930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BC359_16940	COG0505	Belongs to the CarA family
BC359_16950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BC359_16955	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BC359_16960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BC359_16965	COG2151	metal-sulfur cluster biosynthetic enzyme
BC359_16975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_16980	COG1307	EDD domain protein, DegV family
BC359_16985	COG2996	Protein conserved in bacteria
BC359_16990	COG1666	GTP binding
BC359_16995	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_17000	COG3829	transcription factor binding
BC359_17005	COG4187	Peptidase family M20/M25/M40
BC359_17010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC359_17015	COG1012	belongs to the aldehyde dehydrogenase family
BC359_17020	COG1609	Transcriptional regulator
BC359_17025	COG0366	Alpha amylase catalytic
BC359_17030	COG0004	ammonium transporteR
BC359_17035	COG0347	Belongs to the P(II) protein family
BC359_17040	COG1562	ergosterol biosynthetic process
BC359_17055	COG0367	asparagine synthase
BC359_17100	COG1403	HNH endonuclease
BC359_17105	COG0419	ATPase involved in DNA repair
BC359_17110	COG0420	3'-5' exonuclease activity
BC359_17115	COG1074	ATP-dependent DNA helicase activity
BC359_17130	COG0398	Pfam SNARE associated Golgi protein
BC359_17200	COG2224	Isocitrate lyase
BC359_17205	COG0501	Belongs to the peptidase M48B family
BC359_17210	COG1024	Enoyl-CoA hydratase
BC359_17215	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_17220	COG0095	Lipoate-protein ligase
BC359_17225	COG1234	tRNA 3'-trailer cleavage
BC359_17235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC359_17240	COG2207	Transcriptional regulator
BC359_17245	COG2972	Histidine kinase
BC359_17260	COG1309	transcriptional regulator
BC359_17275	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BC359_17280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC359_17285	COG2329	Antibiotic biosynthesis monooxygenase
BC359_17290	COG3069	C4-dicarboxylate transmembrane transporter activity
BC359_17340	COG1388	LysM domain
BC359_17340	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC359_17340	COG3409	Peptidoglycan-binding domain 1 protein
BC359_17415	COG0740	serine-type endopeptidase activity
BC359_17505	COG0305	Participates in initiation and elongation during chromosome replication
BC359_17545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC359_17555	COG1473	amidohydrolase
BC359_17565	COG4473	ABC transporter
BC359_17570	COG1131	(ABC) transporter
BC359_17575	COG0537	adenosine 5'-monophosphoramidase activity
BC359_17580	COG2153	protein acetylation
BC359_17590	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BC359_17605	COG1846	Transcriptional regulator
BC359_17620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC359_17635	COG1668	transmembrane transport
BC359_17640	COG4152	abc transporter atp-binding protein
BC359_17655	COG1024	Enoyl-CoA hydratase
BC359_17660	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_17665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC359_17670	COG0561	phosphatase activity
BC359_17680	COG1131	(ABC) transporter
BC359_17695	COG3679	Belongs to the UPF0342 family
BC359_17705	COG0189	ligase activity
BC359_17710	COG0189	ligase activity
BC359_17715	COG0189	ligase activity
BC359_17720	COG0189	ligase activity
BC359_17730	COG2508	Transcriptional regulator
BC359_17735	COG3842	ATPase activity
BC359_17750	COG1253	flavin adenine dinucleotide binding
BC359_17755	COG0702	epimerase
BC359_17760	COG0351	phosphomethylpyrimidine kinase
BC359_17765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC359_17770	COG2022	thiamine diphosphate biosynthetic process
BC359_17780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC359_17795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC359_17800	COG0765	amino acid transport
BC359_17805	COG1126	abc transporter atp-binding protein
BC359_17810	COG0604	alcohol dehydrogenase
BC359_17820	COG2719	SpoVR family
BC359_17830	COG1268	BioY protein
BC359_17835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC359_17840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC359_17845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BC359_17850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BC359_17855	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC359_17890	COG0840	transmembrane signaling receptor activity
BC359_17895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC359_17900	COG0584	glycerophosphoryl diester phosphodiesterase
BC359_17920	COG3842	ATPase activity
BC359_17925	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC359_17930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BC359_17935	COG3829	transcription factor binding
BC359_17935	COG3290	protein histidine kinase activity
BC359_17940	COG2610	gluconate transmembrane transporter activity
BC359_17945	COG2217	Heavy metal translocating P-type atpase
BC359_17950	COG0586	Pfam SNARE associated Golgi protein
BC359_17960	COG1301	dicarboxylic acid transport
BC359_17965	COG1968	undecaprenyl-diphosphatase activity
BC359_17970	COG1114	Component of the transport system for branched-chain amino acids
BC359_17980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BC359_17995	COG0697	spore germination
BC359_18000	COG0688	phosphatidylethanolamine metabolic process
BC359_18010	COG1846	Transcriptional regulator
BC359_18015	COG2718	Belongs to the UPF0229 family
BC359_18020	COG2766	serine protein kinase
BC359_18025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BC359_18040	COG3382	B3 4 domain protein
BC359_18050	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BC359_18145	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BC359_18330	COG0735	belongs to the Fur family
BC359_18335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BC359_18360	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BC359_18365	COG4129	membrane
BC359_18370	COG1132	(ABC) transporter
BC359_18390	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_18400	COG1194	a g-specific adenine glycosylase
BC359_18405	COG1988	membrane-bound metal-dependent
BC359_18425	COG4221	oxidoreductase activity
BC359_18450	COG1090	epimerase
BC359_18470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC359_18480	COG0840	transmembrane signaling receptor activity
BC359_18485	COG0778	Nitroreductase
BC359_18495	COG1280	lysine exporter protein (LysE YggA)
BC359_18500	COG0778	Nitroreductase
BC359_18510	COG0745	RESPONSE REGULATOR receiver
BC359_18515	COG5002	protein histidine kinase activity
BC359_18520	COG0577	efflux transmembrane transporter activity
BC359_18525	COG1136	(ABC) transporter
BC359_18530	COG1113	amino acid transport
BC359_18550	COG1309	transcriptional regulator
BC359_18565	COG1126	abc transporter atp-binding protein
BC359_18570	COG0765	amino acid transport
BC359_18580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_18630	COG1131	(ABC) transporter
BC359_18645	COG3279	Response regulator of the LytR AlgR family
BC359_18655	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BC359_18660	COG2079	MmgE PrpD family protein
BC359_18665	COG0372	Belongs to the citrate synthase family
BC359_18680	COG0494	nUDIX hydrolase
BC359_18725	COG4974	Belongs to the 'phage' integrase family
BC359_18750	COG1192	Involved in chromosome partitioning
BC359_18770	COG2610	gluconate transmembrane transporter activity
BC359_18775	COG0191	fructose-bisphosphate aldolase activity
BC359_18785	COG2084	Dehydrogenase
BC359_18790	COG1802	Transcriptional regulator
BC359_18805	COG3316	Transposase and inactivated derivatives
BC359_18810	COG1982	Orn Lys Arg decarboxylase major
BC359_18820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC359_18825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC359_18830	COG1263	PTS System
BC359_18830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_18840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC359_18850	COG3316	Transposase and inactivated derivatives
BC359_18865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC359_18910	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BC359_18925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC359_18930	COG0697	spore germination
BC359_18935	COG2207	Transcriptional regulator
BC359_18935	COG0662	Cupin 2, conserved barrel domain protein
BC359_18940	COG1929	Belongs to the glycerate kinase type-1 family
BC359_18950	COG3835	regulator
BC359_18955	COG0583	DNA-binding transcription factor activity
BC359_18960	COG2814	Major facilitator Superfamily
BC359_18970	COG1253	flavin adenine dinucleotide binding
BC359_18985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BC359_18995	COG0477	Major facilitator Superfamily
BC359_18995	COG0477	Major facilitator Superfamily
BC359_19005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BC359_19020	COG1051	belongs to the nudix hydrolase family
BC359_19030	COG0535	radical SAM domain protein
BC359_19040	COG0387	Pfam Sodium calcium exchanger
BC359_19045	COG3871	stress protein (general stress protein 26)
BC359_19090	COG0477	Major facilitator Superfamily
BC359_19100	COG0640	Transcriptional regulator
BC359_19110	COG2217	Heavy metal translocating P-type atpase
BC359_19115	COG1295	ribonuclease BN
BC359_19120	COG4980	gas vesicle protein
BC359_19125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC359_19130	COG4840	Belongs to the UPF0435 family
BC359_19135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BC359_19140	COG2340	Cysteine-rich secretory protein family
BC359_19150	COG0693	protein deglycase activity
BC359_19155	COG1115	amino acid carrier protein
BC359_19165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC359_19165	COG1017	nitric oxide dioxygenase activity
BC359_19170	COG1959	2 iron, 2 sulfur cluster binding
BC359_19175	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BC359_19185	COG0488	(ABC) transporter
BC359_19200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC359_19210	COG2356	endonuclease I
BC359_19225	COG1511	domain protein
BC359_19230	COG0433	COG0433 Predicted ATPase
BC359_19230	COG1674	ftsk spoiiie
BC359_19235	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC359_19240	COG5417	Belongs to the EsaB family
BC359_19245	COG4842	Belongs to the WXG100 family
BC359_19265	COG0513	Belongs to the DEAD box helicase family
BC359_19270	COG0784	Response regulator, receiver
BC359_19270	COG2205	protein histidine kinase activity
BC359_19280	COG3852	Histidine kinase
BC359_19285	COG3290	protein histidine kinase activity
BC359_19290	COG0598	Magnesium transport protein CorA
BC359_19300	COG1115	amino acid carrier protein
BC359_19310	COG2318	DinB family
BC359_19340	COG0693	protein deglycase activity
BC359_19345	COG0745	RESPONSE REGULATOR receiver
BC359_19350	COG3850	Histidine kinase
BC359_19350	COG5002	protein histidine kinase activity
BC359_19365	COG1876	peptidase activity
BC359_19375	COG2070	2-Nitropropane dioxygenase
BC359_19380	COG2706	6-phosphogluconolactonase activity
BC359_19385	COG0024	Methionine aminopeptidase
BC359_19390	COG3852	Histidine kinase
BC359_19395	COG1744	ABC transporter substrate-binding protein PnrA-like
BC359_19400	COG0166	Belongs to the GPI family
BC359_19405	COG1187	pseudouridine synthase activity
BC359_19415	COG0581	inorganic phosphate transmembrane transporter activity
BC359_19420	COG0573	inorganic phosphate transmembrane transporter activity
BC359_19425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC359_19430	COG1132	(ABC) transporter
BC359_19435	COG1253	flavin adenine dinucleotide binding
BC359_19465	COG1404	Belongs to the peptidase S8 family
BC359_19520	COG1597	lipid kinase activity
BC359_19530	COG0154	amidase activity
BC359_19535	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BC359_19545	COG4851	CamS sex pheromone cAM373 precursor
BC359_19550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BC359_19555	COG0210	DNA helicase
BC359_19560	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BC359_19565	COG0423	glycine-tRNA ligase activity
BC359_19570	COG4496	protein, YerC YecD
BC359_19575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BC359_19585	COG0151	Belongs to the GarS family
BC359_19590	COG0138	bifunctional purine biosynthesis protein purh
BC359_19595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BC359_19600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BC359_19605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BC359_19610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC359_19615	COG0047	phosphoribosylformylglycinamidine synthase activity
BC359_19620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC359_19625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BC359_19630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BC359_19635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BC359_19640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BC359_19680	COG2252	PERMEase
BC359_19685	COG0519	Catalyzes the synthesis of GMP from XMP
BC359_19685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BC359_19690	COG1305	Transglutaminase-like
BC359_19695	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BC359_19700	COG0714	Associated with various cellular activities
BC359_19715	COG1733	regulation of RNA biosynthetic process
BC359_19725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC359_19730	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC359_19735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BC359_19745	COG0300	oxidoreductase activity
BC359_19760	COG0459	protein refolding
BC359_19765	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BC359_19770	COG1266	CAAX protease self-immunity
BC359_19780	COG0805	protein transport
BC359_19785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC359_19790	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BC359_19795	COG0488	(ABC) transporter
BC359_19805	COG0456	acetyltransferase
BC359_19810	COG1214	PFAM Peptidase M22, glycoprotease
BC359_19815	COG0802	atpase or kinase
BC359_19905	COG2183	response to ionizing radiation
BC359_19910	COG2208	phosphoserine phosphatase activity
BC359_19915	COG1191	sigma factor activity
BC359_19925	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_19930	COG2208	phosphoserine phosphatase activity
BC359_19935	COG2172	sigma factor antagonist activity
BC359_19940	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_19945	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_19950	COG2337	Toxic component of a toxin-antitoxin (TA) module
BC359_19955	COG0864	Transcriptional regulator
BC359_19960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC359_19965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BC359_19970	COG0736	holo-[acyl-carrier-protein] synthase activity
BC359_19975	COG0705	Rhomboid family
BC359_19980	COG4294	response to UV
BC359_19985	COG0513	Belongs to the DEAD box helicase family
BC359_19990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BC359_19995	COG1181	Belongs to the D-alanine--D-alanine ligase family
BC359_20005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BC359_20015	COG1176	ABC-type spermidine putrescine transport system, permease component I
BC359_20020	COG3842	ATPase activity
BC359_20030	COG3527	Alpha-acetolactate decarboxylase
BC359_20040	COG0246	Mannitol dehydrogenase
BC359_20045	COG3711	transcriptional antiterminator
BC359_20050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC359_20050	COG2213	PTS system mannitol-specific
BC359_20060	COG1556	Lactate utilization protein
BC359_20065	COG1139	Iron-sulfur cluster binding protein
BC359_20070	COG0247	lactate metabolic process
BC359_20075	COG2186	Transcriptional regulator
BC359_20080	COG1620	l-lactate permease
BC359_20090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BC359_20095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC359_20100	COG4856	YbbR-like protein
BC359_20105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BC359_20110	COG5662	AntiSigma factor
BC359_20115	COG1595	DNA-templated transcription, initiation
BC359_20185	COG0726	polysaccharide deacetylase
BC359_20190	COG2194	sulfuric ester hydrolase activity
BC359_20200	COG0489	protein tyrosine kinase activity
BC359_20205	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_20230	COG3341	Caulimovirus viroplasmin
BC359_20230	COG0328	RNA-DNA hybrid ribonuclease activity
BC359_20335	COG3316	Transposase and inactivated derivatives
BC359_20365	COG1073	alpha beta
BC359_20370	COG5002	protein histidine kinase activity
BC359_20375	COG2197	response regulator
BC359_20450	COG0791	NLP P60 protein
BC359_20450	COG0741	lytic transglycosylase activity
BC359_20520	COG1376	ErfK ybiS ycfS ynhG family protein
BC359_20565	COG3708	Transcriptional regulator
BC359_20565	COG2207	Transcriptional regulator
BC359_20575	COG3316	Transposase and inactivated derivatives
BC359_20595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_20620	COG3316	Transposase and inactivated derivatives
BC359_20650	COG3316	Transposase and inactivated derivatives
BC359_20670	COG5002	protein histidine kinase activity
BC359_20675	COG2002	toxin-antitoxin pair type II binding
BC359_20720	COG1380	Effector of murein hydrolase LrgA
BC359_20725	COG1346	cytolysis
BC359_20745	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BC359_20750	COG0583	DNA-binding transcription factor activity