locus-tag class description BGM20_00030 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BGM20_00035 ENOG4105EMS pseudouridine synthase BGM20_00050 ENOG4105ETU transcriptional activator (TenA BGM20_00070 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) BGM20_00075 ENOG4105D06 uba thif-type nad fad binding protein BGM20_00080 ENOG4105DWF phosphomethylpyrimidine kinase BGM20_00085 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BGM20_00090 ENOG4107A88 BGM20_00145 ENOG4105ENA helicase BGM20_00160 ENOG4108ZMI UPF0477 protein BGM20_00170 ENOG4105C28 cystathionine BGM20_00175 ENOG4105C28 cystathionine BGM20_00180 ENOG4105D9U N-acetyltransferase BGM20_00185 ENOG4105JHY Membrane BGM20_00210 ENOG4106BHF BGM20_00215 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BGM20_00255 ENOG4108PSK reductase BGM20_00270 ENOG4105DM4 PTS System BGM20_00275 ENOG4105DG6 mannose-6-phosphate isomerase BGM20_00280 ENOG4105G7B Protein of unknown function (DUF2992) BGM20_00285 ENOG4105VMI -acetyltransferase BGM20_00295 ENOG4108Z66 YbaK ebsC protein BGM20_00310 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BGM20_00320 ENOG4108ZJ4 polysaccharide deacetylase BGM20_00325 ENOG4107CUJ Protein of unknown function (DUF2690) BGM20_00355 ENOG4108IEG Formate dehydrogenase Alpha subunit BGM20_00385 ENOG41087PP glycosyltransferase MGT family BGM20_00395 ENOG4105EXQ uroporphyrinogen iii synthase hem4 BGM20_00400 ENOG4105C4B ABC transporter, permease BGM20_00405 ENOG4108IXI (ABC) transporter BGM20_00415 ENOG4105Q95 Cupin 2, conserved barrel domain protein BGM20_00430 ENOG4105D2H Uronic isomerase BGM20_00435 ENOG4105CT4 transporter BGM20_00440 ENOG4105DG4 malate L-lactate dehydrogenase BGM20_00445 ENOG4105CPQ Dehydrogenase BGM20_00450 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BGM20_00455 ENOG4105DMW Dehydrogenase reductase BGM20_00465 ENOG4107KJX Transcriptional regulator BGM20_00470 ENOG4107QZW Altronate oxidoreductase BGM20_00475 ENOG4105CTX dehydratase BGM20_00480 ENOG4107TSN permease BGM20_00490 ENOG4105JD4 ATPase yjob BGM20_00505 ENOG41068K0 YCII-related domain BGM20_00510 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BGM20_00515 ENOG4105KWG Pfam:DUF1696 BGM20_00520 ENOG4105K7W phage-related replication protein BGM20_00525 ENOG4105WEF catalase BGM20_00530 ENOG410635T phage-like element pbsx protein BGM20_00580 ENOG4108TFU terminase (Small subunit) BGM20_00585 ENOG4105IG6 Phage terminase, large subunit BGM20_00590 ENOG4108MDF Phage Portal Protein BGM20_00615 ENOG41060SN BGM20_00630 ENOG4105PQS phage protein BGM20_00635 ENOG4105FR7 XkdM protein, phage-like element PBSX BGM20_00640 ENOG4105MTC XkdN-like protein BGM20_00650 ENOG4108FKH Transglycosylase SLT domain BGM20_00650 ENOG4108FKH Transglycosylase SLT domain BGM20_00655 ENOG4108WZM domain protein BGM20_00660 ENOG4105X7F BGM20_00670 ENOG4105MFU Protein of unknown function (DUF2634) BGM20_00675 ENOG41066EA baseplate J family protein BGM20_00680 ENOG410906S phage-like element pbsx protein xkdt BGM20_00690 ENOG41068G1 BGM20_00720 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BGM20_00735 ENOG4105CJ3 phosphate transporter BGM20_00740 ENOG4107GRR phosphate transport regulator BGM20_00745 ENOG4107R7I amino acid BGM20_00755 ENOG4105EDW glycosyl transferase, family 39 BGM20_00760 ENOG4105CKK Glycosyl transferase, family 2 BGM20_00770 ENOG4105C0H protease BGM20_00780 ENOG4108ME1 Peptidase M55 D-aminopeptidase BGM20_00785 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BGM20_00790 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGM20_00795 ENOG4105C3U ABC transporter BGM20_00805 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BGM20_00810 ENOG4105DTQ mandelate racemase muconate lactonizing BGM20_00815 ENOG4107SN7 NLP P60 protein BGM20_00820 ENOG4108JQ7 (ABC) transporter BGM20_00825 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BGM20_00830 ENOG4107TUM Amidinotransferase BGM20_00835 ENOG4108S4H thioesterase Superfamily protein BGM20_00840 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BGM20_00860 ENOG4108428 Inherit from COG: -acetyltransferase BGM20_00870 ENOG41080TC multidrug resistance protein BGM20_00875 ENOG4105CIY formyltetrahydrofolate deformylase BGM20_00880 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BGM20_00895 ENOG4105K56 Transcriptional regulator BGM20_00900 ENOG4108ZHJ Organic hydroperoxide resistance protein BGM20_00905 ENOG4107Y2X deaminase BGM20_00910 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BGM20_00915 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BGM20_00925 ENOG4108W7F transporter, permease BGM20_00930 ENOG4108JJB ABC transporter BGM20_00935 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein BGM20_00940 ENOG4108X43 YKOF domain protein BGM20_00945 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGM20_00950 ENOG41062D9 Histidine kinase BGM20_00960 ENOG4106849 propeptide, pepSY amd peptidase M4 BGM20_00980 ENOG4105CJW magnesium transporter BGM20_00985 ENOG4105V75 Transcriptional regulator BGM20_01030 ENOG4105DQE DNA ligase BGM20_01035 ENOG4105FDF Could be involved in DNA repair (By similarity) BGM20_01040 ENOG4105BZU Histidine kinase BGM20_01045 ENOG4107T5V SNARE associated Golgi BGM20_01050 ENOG4107TS3 membrane protein, TerC BGM20_01055 ENOG4108WZW RNA polymerase sigma BGM20_01065 ENOG410681C small acid-soluble spore protein BGM20_01075 ENOG4105D0M Protease HtpX homolog BGM20_01095 ENOG4108TGC Acyltransferase BGM20_01100 ENOG4105BZU Histidine kinase BGM20_01105 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BGM20_01115 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BGM20_01120 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BGM20_01125 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BGM20_01135 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit BGM20_01140 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) BGM20_01145 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BGM20_01150 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BGM20_01170 ENOG4105BZU Histidine kinase BGM20_01175 ENOG41090MY MarR family Transcriptional regulator BGM20_01180 ENOG4105ER2 Ompa motb domain protein BGM20_01185 ENOG4105E14 MotA TolQ exbB proton channel BGM20_01195 ENOG4108K88 Membrane BGM20_01200 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BGM20_01205 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase BGM20_01210 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BGM20_01215 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BGM20_01225 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr BGM20_01265 ENOG4105F0V Cell wall hydrolase BGM20_01280 ENOG4105C59 p-type ATPase BGM20_01290 ENOG4105DC7 peptidase M24 BGM20_01305 ENOG4105CID antiterminator BGM20_01315 ENOG4105KRI phosphocarrier protein (HPr BGM20_01320 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BGM20_01330 ENOG4105F6S Spore photoproduct lyase BGM20_01340 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BGM20_01350 ENOG4105K4I Scp-like extracellular BGM20_01360 ENOG4105BZU Histidine kinase BGM20_01365 ENOG4105CHM Aminotransferase BGM20_01375 ENOG4107R88 Chemotaxis protein (CheV) BGM20_01380 ENOG4105UIN BGM20_01390 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein BGM20_01400 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BGM20_01405 ENOG4105EPM Diguanylate phosphodiesterase BGM20_01415 ENOG4107IN1 Protein of unknown function (DUF1797) BGM20_01420 ENOG4108XRC Protein of unknown function (DUF458) BGM20_01450 ENOG4105NQC Flavodoxin BGM20_01460 ENOG4105CH2 amidohydrolase BGM20_01470 ENOG4105D8X mechanosensitive ion channel BGM20_01475 ENOG4105D3R alkyl hydroperoxide reductase BGM20_01480 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BGM20_01500 ENOG4105D06 uba thif-type nad fad binding protein BGM20_01505 ENOG4105CVM Molybdenum cofactor synthesis domain protein BGM20_01510 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BGM20_01515 ENOG4108ZAF Molybdopterin BGM20_01520 ENOG41067WU Molybdopterin converting factor (Subunit 1) BGM20_01525 ENOG4105BZ1 (ABC) transporter BGM20_01530 ENOG4105BZ1 (ABC) transporter BGM20_01540 ENOG4107X8C Efflux transporter RND family MFP subunit BGM20_01545 ENOG4105C19 ABC transporter BGM20_01550 ENOG4107RBB ABC transporter, permease BGM20_01555 ENOG4105E98 transcriptional regulator DeoR family BGM20_01560 ENOG4105DE4 1-phosphofructokinase BGM20_01565 ENOG4105DM4 PTS System BGM20_01570 ENOG4105C3F Signal peptidase i BGM20_01580 ENOG4105C5H ABC transporter BGM20_01585 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BGM20_01610 ENOG4105BZU Histidine kinase BGM20_01620 ENOG4107ZYR domain protein BGM20_01630 ENOG4105CN5 Metallo-Beta-Lactamase BGM20_01640 ENOG4108X4Q Hydrolase BGM20_01645 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BGM20_01665 ENOG4105CPP Dehydrogenase, E1 component BGM20_01670 ENOG4105C7S Dehydrogenase BGM20_01675 ENOG4107QN2 dihydrolipoyl dehydrogenase BGM20_01685 ENOG4105CXN decarboxylase BGM20_01690 ENOG4105WBI UPF0223 protein BGM20_01705 ENOG4105ECY inositol monophosphatase BGM20_01715 ENOG4105JQZ Methyltransferase BGM20_01755 ENOG4105CI3 gtp-binding protein typa BGM20_01760 ENOG4105QA2 BGM20_01775 ENOG4108IAB Phoh family BGM20_01785 ENOG4105CSV Glutaminase BGM20_01790 ENOG4105ZPI UPF0358 protein BGM20_01795 ENOG4105CNI cell division protein FtsW BGM20_01800 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BGM20_01810 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BGM20_01825 ENOG4105CCU oxidase (Subunit III) BGM20_01830 ENOG41064X9 cytochrome C oxidase subunit IV BGM20_01845 ENOG41080XQ Signal transduction protein with cbs domains BGM20_01850 ENOG4106UY4 Inherit from COG: Scp-like extracellular BGM20_01870 ENOG4105WUC UPF0298 protein BGM20_01875 ENOG4106H78 methyltransferase BGM20_01880 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BGM20_01885 ENOG4105H20 Sporulation integral membrane protein YlbJ BGM20_01890 ENOG4105D78 K07001 NTE family protein BGM20_01895 ENOG41063PX domain protein BGM20_01900 ENOG4105CDE UPF0348 protein BGM20_01910 ENOG4105KNH Nucleic acid-binding protein BGM20_01915 ENOG41067VY 50S ribosomal protein L32 BGM20_01940 ENOG4108V6E Cell division protein mraZ BGM20_01945 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BGM20_01955 ENOG4105CJN penicillin-binding protein BGM20_01965 ENOG4105CJN penicillin-binding protein BGM20_01975 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BGM20_01985 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BGM20_01990 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BGM20_01995 ENOG4105CNI cell division protein FtsW BGM20_02000 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BGM20_02005 ENOG4105D4A Cell wall formation (By similarity) BGM20_02010 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BGM20_02015 ENOG4108R2U division initiation protein BGM20_02025 ENOG4105K67 small basic protein BGM20_02030 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BGM20_02035 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BGM20_02045 ENOG4105FFI sigma-e processing peptidase spoiiga BGM20_02050 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM20_02060 ENOG4105DKW ABC transporter BGM20_02070 ENOG4105WR5 sporulation protein, YlmC YmxH family BGM20_02075 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BGM20_02080 ENOG4105DFA alanine racemase domain protein BGM20_02085 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) BGM20_02090 ENOG41067XK integral membrane protein BGM20_02095 ENOG4105DBK s4 domain protein BGM20_02105 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BGM20_02115 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BGM20_02120 ENOG4105C34 Pseudouridine synthase BGM20_02125 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) BGM20_02135 ENOG4105CXT aspartate transcarbamylase BGM20_02145 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BGM20_02150 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BGM20_02155 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BGM20_02160 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) BGM20_02165 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BGM20_02170 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BGM20_02175 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) BGM20_02185 ENOG4107S4M Sulfate adenylate transferase BGM20_02190 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BGM20_02195 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BGM20_02200 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BGM20_02205 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BGM20_02210 ENOG4105F23 Fibronectin-binding protein BGM20_02220 ENOG4105DSJ YicC domain protein BGM20_02225 ENOG4105KC4 UPF0296 protein BGM20_02230 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BGM20_02240 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BGM20_02245 ENOG4105C25 Primosomal protein n' BGM20_02250 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BGM20_02255 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BGM20_02260 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BGM20_02265 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BGM20_02270 ENOG4108ZF3 Phosphatase BGM20_02275 ENOG4105D9P serine threonine protein kinase BGM20_02280 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BGM20_02285 ENOG4105DJV ribulose-phosphate 3-epimerase BGM20_02290 ENOG4105FJ0 thiamine BGM20_02300 ENOG4105VB9 50S ribosomal protein l28 BGM20_02305 ENOG4108ZAA Alkaline-shock protein BGM20_02310 ENOG4105DP4 dak2 domain fusion protein ylov BGM20_02320 ENOG4105EJQ L-serine dehydratase BGM20_02325 ENOG4105CB5 ATP-dependent DNA helicase recG BGM20_02330 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) BGM20_02340 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BGM20_02345 ENOG4105CHR reductase BGM20_02350 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BGM20_02355 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BGM20_02360 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BGM20_02365 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BGM20_02375 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) BGM20_02385 ENOG4105K5M 30s ribosomal protein S16 BGM20_02390 ENOG4108BW8 UPF0109 protein BGM20_02400 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) BGM20_02405 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BGM20_02410 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) BGM20_02415 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BGM20_02420 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BGM20_02430 ENOG4105VM1 flagellar BGM20_02435 ENOG4105CMV Succinyl-CoA synthetase subunit beta BGM20_02440 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BGM20_02450 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BGM20_02455 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) BGM20_02460 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BGM20_02465 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BGM20_02470 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BGM20_02480 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BGM20_02485 ENOG4108ZC9 flagellar basal-body rod protein flgc BGM20_02490 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BGM20_02495 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BGM20_02500 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BGM20_02515 ENOG4106YF4 Flagellar biosynthesis chaperone BGM20_02525 ENOG410696Y Flagellar hook-length control protein BGM20_02530 ENOG410822I Flagellar hook capping protein BGM20_02535 ENOG4108JQA flagellar BGM20_02540 ENOG41068WV flagellar FlbD family protein BGM20_02550 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BGM20_02555 ENOG4105DD5 Flagellar motor switch protein BGM20_02560 ENOG4107YTP response regulator receiver protein BGM20_02570 ENOG4105CN7 Flagellar biosynthetic protein FliP BGM20_02575 ENOG4105VS8 Flagellar biosynthetic protein fliq BGM20_02580 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BGM20_02585 ENOG4105D00 flagellar biosynthetic protein flhB BGM20_02590 ENOG4105D7B Flagellar biosynthesis protein flha BGM20_02595 ENOG4105FZW flagellar biosynthesis regulator FlhF BGM20_02605 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BGM20_02610 ENOG4105CBS Chea signal transduction histidine kinase BGM20_02615 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis BGM20_02630 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM20_02640 ENOG4105CE9 30S ribosomal protein S2 BGM20_02645 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) BGM20_02655 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BGM20_02660 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BGM20_02665 ENOG4105KNE Phosphatidate cytidylyltransferase BGM20_02675 ENOG4105DZP Membrane-associated zinc metalloprotease BGM20_02680 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BGM20_02690 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BGM20_02695 ENOG4105CHV Transcription elongation factor NusA BGM20_02700 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BGM20_02705 ENOG4105VHM ribosomal protein BGM20_02710 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BGM20_02715 ENOG4105W7A Protein of unknown function (DUF503) BGM20_02720 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BGM20_02725 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BGM20_02730 ENOG4105DTN riboflavin biosynthesis protein ribF BGM20_02735 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) BGM20_02740 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BGM20_02750 ENOG4105C1V Peptidase, M16 BGM20_02765 ENOG4105E35 Dipicolinate synthase subunit A BGM20_02770 ENOG4108S0H Dipicolinic acid synthetase, b subunit BGM20_02775 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BGM20_02785 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BGM20_02805 ENOG4105CNU cell division protein FtsK BGM20_02810 ENOG4105FDP GntR family transcriptional regulator BGM20_02830 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BGM20_02835 ENOG4105XZV Protein of unknown function (DUF3243) BGM20_02850 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BGM20_02855 ENOG4105CEV competence damage-inducible protein BGM20_02865 ENOG4108A04 Beta-lactamase BGM20_02870 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) BGM20_02875 ENOG4105D48 metallophosphoesterase BGM20_02880 ENOG4105MCT stage V sporulation protein S BGM20_02890 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BGM20_02895 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BGM20_02910 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) BGM20_02915 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BGM20_02930 ENOG4105IIP Membrane BGM20_02935 ENOG4105W1N transcriptional regulator BGM20_02940 ENOG4108151 Beta-lactamase domain protein BGM20_02950 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BGM20_02960 ENOG4107QKG PfaD family BGM20_02965 ENOG41062T2 Acyl carrier protein BGM20_02970 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase BGM20_02975 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BGM20_02980 ENOG4108MGH Enoyl-CoA hydratase BGM20_02985 ENOG4108KQ6 Enoyl-CoA hydratase BGM20_02995 ENOG4107SQU synthase BGM20_03005 ENOG4105C0W non-ribosomal peptide synthetase BGM20_03015 ENOG4106A3M Cytochrome p-450 BGM20_03040 ENOG4105K7W phage-related replication protein BGM20_03045 ENOG4108X3M OsmC Ohr family protein BGM20_03050 ENOG410814C multidrug resistance protein BGM20_03070 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BGM20_03075 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BGM20_03090 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BGM20_03095 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BGM20_03100 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BGM20_03105 ENOG4105U6W MutT NUDIX family protein BGM20_03110 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BGM20_03115 ENOG4106F1P AAA ATPase, central domain protein BGM20_03125 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BGM20_03130 ENOG4105CXI aluminum resistance protein BGM20_03135 ENOG4105KV4 Transcriptional regulator BGM20_03140 ENOG4105C5F glutamine synthetase BGM20_03180 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin BGM20_03225 ENOG41079P0 BGM20_03250 ENOG4106WTF Glycosyl transferase, family 2 BGM20_03255 ENOG4107RGC Glycosyl transferase, family 2 BGM20_03280 ENOG4107NTZ BGM20_03295 ENOG410907G BGM20_03300 ENOG4105CT4 transporter BGM20_03305 ENOG4105DSG hydrolase family 43 BGM20_03310 ENOG4105E2R ROK family BGM20_03315 ENOG4105C93 Xylose Isomerase BGM20_03320 ENOG4105CMG Carbohydrate kinase BGM20_03325 ENOG4107Y9E nuclease BGM20_03330 ENOG4105C54 Major Facilitator superfamily BGM20_03335 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BGM20_03345 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BGM20_03415 ENOG4108NHD germination protein BGM20_03430 ENOG4105FVX BGM20_03440 ENOG4105K7W phage-related replication protein BGM20_03450 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BGM20_03460 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BGM20_03470 ENOG4108SVB resolvase BGM20_03475 ENOG4105VPS UPF0291 protein BGM20_03480 ENOG4105CV1 Transketolase (EC 2.2.1.1) BGM20_03500 ENOG4107QIV Cytochrome c biogenesis protein BGM20_03525 ENOG4107DZX Small, acid-soluble spore protein P BGM20_03535 ENOG4108I0Z Aconitate hydratase BGM20_03540 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BGM20_03555 ENOG41067CD Small, acid-soluble spore protein Tlp BGM20_03565 ENOG4105MI2 BGM20_03570 ENOG4105W8X HesB YadR YfhF-family protein BGM20_03575 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BGM20_03580 ENOG4105K4P CoA-binding domain protein BGM20_03585 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGM20_03610 ENOG4107QWR cellulase (EC 3.2.1.4) BGM20_03620 ENOG4108MYR Secreted protein BGM20_03625 ENOG4107SYN Glycosyl hydrolases family 43 BGM20_03640 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BGM20_03645 ENOG4107T5V SNARE associated Golgi BGM20_03655 ENOG4107QX3 carboxylase BGM20_03660 ENOG4105E39 Enoyl-CoA hydratase BGM20_03665 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BGM20_03670 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BGM20_03675 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BGM20_03680 ENOG4105CEY Amp-dependent synthetase and ligase BGM20_03685 ENOG4105C1G acyl-Coa dehydrogenase BGM20_03700 ENOG4105F32 YngK protein BGM20_03705 ENOG4106U2H Protein of unknown function (DUF1360) BGM20_03720 ENOG4105C0W non-ribosomal peptide synthetase BGM20_03730 ENOG4105C0W non-ribosomal peptide synthetase BGM20_03735 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family BGM20_03740 ENOG4108N2V aldose 1-epimerase BGM20_03745 ENOG4107QJQ Mate efflux family protein BGM20_03770 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BGM20_03775 ENOG4105SKE transcriptional Regulator LysR family BGM20_03780 ENOG4105CB2 alcohol dehydrogenase BGM20_03785 ENOG4105BZ8 glutamate synthase BGM20_03790 ENOG4105CBC glutamate synthase BGM20_03795 ENOG4105C5Q Transcriptional regulator BGM20_03800 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BGM20_03805 ENOG4105II7 pyrroline-5-carboxylate reductase BGM20_03825 ENOG4108UB7 BGM20_03830 ENOG41068WN BGM20_03835 ENOG4105IE8 Alpha-ketoglutarate permease BGM20_03840 ENOG4107U6E carbohydrate kinase FGGY BGM20_03845 ENOG4108M3J Dehydrogenase BGM20_03850 ENOG4108J2R molybdopterin oxidoreductase BGM20_03875 ENOG4105EC8 Methyl-accepting chemotaxis BGM20_03885 ENOG4108YQE rare lipoprotein a BGM20_03890 ENOG4105XPP Protein of unknown function (DUF1275) BGM20_03895 ENOG4108NR7 pectate lyase BGM20_03900 ENOG4108RAV Conserved protein BGM20_03920 ENOG4105EPI acetyltransferase, (GNAT) family BGM20_03940 ENOG41073R8 VanW family BGM20_03950 ENOG4105VMP Transcriptional regulator BGM20_03955 ENOG4105NX3 Membrane BGM20_03965 ENOG4108Q5Y Membrane BGM20_03975 ENOG4108V4B ThiJ pfpI BGM20_03980 ENOG4108J4B Beta-lactamase BGM20_04005 ENOG4107T94 Endo-14-beta-xylanase BGM20_04015 ENOG4105YB8 TM2 domain containing protein BGM20_04085 ENOG4108Z7R Chaperone CsaA BGM20_04090 ENOG4105FTV AraC Family Transcriptional Regulator BGM20_04095 ENOG4108HJF gCN5-related N-acetyltransferase BGM20_04105 ENOG4108W8B Beta-lactamase domain protein BGM20_04115 ENOG4105D29 Helix-turn-helix type 11 domain protein BGM20_04125 ENOG4105KTU Transcriptional regulator, arsr family BGM20_04135 ENOG4108SJC Membrane BGM20_04155 ENOG4105ECK Fatty Acid Desaturase BGM20_04160 ENOG4108ZGX Histidine kinase BGM20_04165 ENOG4108S01 response regulator BGM20_04175 ENOG41069ER domain protein BGM20_04180 ENOG4105C9U ATP-dependent DNA helicase RecQ BGM20_04195 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BGM20_04200 ENOG4105SCY DNAK suppressor BGM20_04240 ENOG4105C26 Dehydrogenase BGM20_04245 ENOG4105EWU Squalene--hopene cyclase BGM20_04250 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BGM20_04255 ENOG4105C8J )-transporter BGM20_04260 ENOG4105C09 Bile acid BGM20_04265 ENOG4105C7S Dehydrogenase BGM20_04275 ENOG4107T89 von Willebrand factor, type A BGM20_04280 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BGM20_04290 ENOG4105K4H Nlp p60 protein BGM20_04295 ENOG41087PP glycosyltransferase MGT family BGM20_04305 ENOG4107QMU Mate efflux family protein BGM20_04310 ENOG4106SCS STAS domain BGM20_04330 ENOG4105FR1 rard protein BGM20_04345 ENOG4105C6Z Gluconate BGM20_04350 ENOG41090U3 tautomerase BGM20_04365 ENOG4105FBA Phospholipase Carboxylesterase BGM20_04380 ENOG4105E1V na solute symporter BGM20_04400 ENOG4108VXD carboxy-peptidase BGM20_04405 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BGM20_04415 ENOG4106Z5R BGM20_04420 ENOG410841Q phosphoesterase PA-phosphatase related protein BGM20_04455 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BGM20_04460 ENOG4108TSC N-acetyltransferase BGM20_04465 ENOG4107S4Y M20 DapE family protein YgeY BGM20_04480 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BGM20_04520 ENOG4107T32 3-phytase (EC 3.1.3.8) BGM20_04530 ENOG4105C5E polysaccharide biosynthesis protein BGM20_04535 ENOG4105E0X reductase BGM20_04560 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) BGM20_04565 ENOG41090WU lipolytic protein G-D-S-L family BGM20_04570 ENOG4108KF3 Electron transport protein SCO1 SenC BGM20_04585 ENOG4105C7B Threonine dehydratase BGM20_04595 ENOG4108UT2 hemolysin iii BGM20_04605 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BGM20_04610 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BGM20_04625 ENOG4107YX5 Pfam:DUF548 BGM20_04630 ENOG4108Y6J UPF0403 protein BGM20_04635 ENOG4105C01 Dihydroxy-acid dehydratase BGM20_04650 ENOG4108V06 Glutathione peroxidase BGM20_04655 ENOG4105CVG Homoserine O-transsuccinylase BGM20_04695 ENOG41081VK Ribonuclease BGM20_04725 ENOG410890F Dynamin family BGM20_04735 ENOG41065KQ synthase BGM20_04740 ENOG4105C2W permease BGM20_04745 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BGM20_04750 ENOG4105CTD carboxy-peptidase BGM20_04755 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) BGM20_04765 ENOG4105D7K pfkb domain protein BGM20_04770 ENOG4108M60 Transcriptional regulator BGM20_04780 ENOG4105CHR reductase BGM20_04785 ENOG4105DVT helicase BGM20_04795 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BGM20_04810 ENOG4108UKS UPF0398 protein BGM20_04825 ENOG4108I5C dEAD DEAH box helicase BGM20_04875 ENOG4105BZ4 penicillin-binding protein BGM20_04885 ENOG4105CSM endonuclease III BGM20_04895 ENOG4105C5S asparaginyl-tRNA synthetase BGM20_04900 ENOG4105CHM Aminotransferase BGM20_04910 ENOG4105YAC BGM20_04915 ENOG4105DVT helicase BGM20_04920 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) BGM20_04925 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) BGM20_04930 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BGM20_04935 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BGM20_04940 ENOG4105DJ0 Poly(A) Polymerase BGM20_04945 ENOG4105CPK Glycosyl transferase (Group 1 BGM20_04950 ENOG4105FJR Lmbe family BGM20_04955 ENOG4108Z5K methylglyoxal synthase BGM20_04960 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BGM20_04965 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BGM20_04970 ENOG4108JYZ YitT family BGM20_05010 ENOG41068YB TPR repeat-containing protein BGM20_05015 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BGM20_05035 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BGM20_05040 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BGM20_05050 ENOG4108I0Q anthranilate phosphoribosyltransferase BGM20_05055 ENOG4105CRQ synthase (Component I) BGM20_05060 ENOG4105KHN chorismate mutase BGM20_05065 ENOG4105D49 3-dehydroquinate synthase BGM20_05070 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BGM20_05075 ENOG4105BZU Histidine kinase BGM20_05085 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BGM20_05090 ENOG4105EAH synthase BGM20_05095 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BGM20_05100 ENOG4105XXQ heptaprenyl diphosphate synthase component I BGM20_05110 ENOG4105EUJ GTP cyclohydrolase i BGM20_05115 ENOG4105K70 DNA-binding protein BGM20_05120 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BGM20_05135 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BGM20_05140 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BGM20_05145 ENOG41065D1 BGM20_05150 ENOG4105S2F BGM20_05165 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) BGM20_05170 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BGM20_05175 ENOG4105CAT Cytidine monophosphate kinase BGM20_05190 ENOG4105MSI germination protein ypeb BGM20_05200 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) BGM20_05220 ENOG4107RGJ metallophosphoesterase BGM20_05235 ENOG4105I7S Abortive infection protein BGM20_05245 ENOG4105T7X BGM20_05255 ENOG4108SAX Membrane BGM20_05260 ENOG4108JQ1 Dehydrogenase BGM20_05265 ENOG4105FF2 Type I DHQase BGM20_05280 ENOG4105BZU Histidine kinase BGM20_05285 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGM20_05290 ENOG4105CRE cytochrome C BGM20_05295 ENOG4107TWT Cytochrome c biogenesis protein BGM20_05305 ENOG4105FE9 pseudouridine synthase BGM20_05315 ENOG4108JIC nucleoside recognition domain protein BGM20_05320 ENOG4105DZ1 carboxypeptidase BGM20_05330 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BGM20_05335 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BGM20_05350 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BGM20_05355 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BGM20_05360 ENOG4108R6K riboflavin synthase, subunit alpha BGM20_05365 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BGM20_05375 ENOG4105C3F Signal peptidase i BGM20_05380 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) BGM20_05400 ENOG4107ZE5 PPIases accelerate the folding of proteins BGM20_05405 ENOG4105PTM secreted protein BGM20_05410 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BGM20_05420 ENOG4105G6R Stage v sporulation protein ae BGM20_05435 ENOG41090VF Stage v sporulation protein ac BGM20_05450 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM20_05455 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BGM20_05460 ENOG41082AN stage II sporulation protein BGM20_05465 ENOG4105DZ1 carboxypeptidase BGM20_05470 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BGM20_05475 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BGM20_05480 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BGM20_05490 ENOG4105I3K Ferric uptake regulator, Fur family BGM20_05495 ENOG4105MZ9 stage II sporulation protein m BGM20_05510 ENOG4105DFD Na H antiporter BGM20_05515 ENOG4108IJ0 Aspartate ammonia-lyase BGM20_05520 ENOG4105HDK L-asparaginase BGM20_05525 ENOG4108IMY Transcriptional regulator BGM20_05535 ENOG4108YZ4 nudix hydrolase BGM20_05545 ENOG4105CPC Aldo Keto reductase BGM20_05565 ENOG4106HZJ BGM20_05570 ENOG4105RHY Pfam:UPF0157 BGM20_05575 ENOG4105KAC Antibiotic biosynthesis monooxygenase BGM20_05580 ENOG4108XET gCN5-related N-acetyltransferase BGM20_05590 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BGM20_05600 ENOG4105E5W Transporter BGM20_05610 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase BGM20_05625 ENOG4108IXY short-chain dehydrogenase reductase BGM20_05630 ENOG41069FQ Metallo-beta-lactamase superfamily BGM20_05635 ENOG4105II7 pyrroline-5-carboxylate reductase BGM20_05645 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BGM20_05655 ENOG410861F 50S ribosomal protein L33 BGM20_05660 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BGM20_05665 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BGM20_05670 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BGM20_05675 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BGM20_05685 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) BGM20_05690 ENOG4108NA0 Uncharacterized conserved protein (COG2071) BGM20_05695 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BGM20_05700 ENOG4108HNZ carboxyl transferase BGM20_05705 ENOG4108ZVT methylmalonyl-coA epimerase BGM20_05715 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BGM20_05720 ENOG4108QEG Membrane BGM20_05725 ENOG4105CDA abc transporter atp-binding protein BGM20_05730 ENOG4105E5Q amino acid AbC transporter BGM20_05735 ENOG4108HW3 (ABC) transporter BGM20_05740 ENOG4108Y6J UPF0403 protein BGM20_05745 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BGM20_05760 ENOG4105C7S Dehydrogenase BGM20_05765 ENOG4105CPP Dehydrogenase, E1 component BGM20_05780 ENOG4105CKM Branched-chain carboxylic acid kinase BGM20_05785 ENOG4107RDP Dehydrogenase BGM20_05795 ENOG4108JUB Transcriptional regulator BGM20_05800 ENOG4106CCJ Protein of unknown function (DUF2627) BGM20_05805 ENOG4105CR4 methylisocitrate lyase BGM20_05810 ENOG4105DXD 2-methylcitrate dehydratase BGM20_05820 ENOG4105C1G acyl-Coa dehydrogenase BGM20_05825 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BGM20_05840 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BGM20_05855 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BGM20_05865 ENOG4107QQR Sporulation BGM20_05875 ENOG4105S1Z Stage IV sporulation protein B BGM20_05880 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BGM20_05885 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BGM20_05890 ENOG4105DX0 Hemolysin A BGM20_05900 ENOG4105CTB Polyprenyl synthetase BGM20_05905 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BGM20_05910 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BGM20_05915 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BGM20_05920 ENOG4105M7K Involved in the transcription termination process (By similarity) BGM20_05925 ENOG4108ZSR alkaline shock protein BGM20_05930 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BGM20_05950 ENOG410644B Stage III sporulation protein af BGM20_05960 ENOG4105KQ4 Stage iii sporulation protein ad BGM20_05965 ENOG4108CQH stage III sporulation protein AC BGM20_05970 ENOG4105KR5 Stage iii sporulation protein BGM20_05975 ENOG4105CD2 stage iii sporulation protein aa BGM20_05985 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BGM20_05990 ENOG4105DC7 peptidase M24 BGM20_05995 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BGM20_06005 ENOG4105CBJ Metal-dependent enzyme BGM20_06020 ENOG4105KST dependent repressor BGM20_06025 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BGM20_06030 ENOG4105WZW rhodanese family BGM20_06040 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BGM20_06045 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) BGM20_06050 ENOG4105C0D helicase BGM20_06065 ENOG4108IMY Transcriptional regulator BGM20_06075 ENOG4105VFR signal peptidase BGM20_06135 ENOG41080XP Cbs domain BGM20_06145 ENOG4105C37 (CBS) domain BGM20_06170 ENOG4105C5X domain protein BGM20_06195 ENOG4105E0M Sulfatase BGM20_06210 ENOG4107ZXI Rhomboid family BGM20_06220 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BGM20_06225 ENOG4105WDJ 50S ribosomal protein L33 BGM20_06245 ENOG41068DG YceG-like family BGM20_06250 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BGM20_06255 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BGM20_06260 ENOG4105E2Z phosphate ABC transporter (Permease BGM20_06265 ENOG4105C8U phosphate abc transporter BGM20_06270 ENOG4105CVA phosphate BGM20_06275 ENOG4107RF6 penicillin-binding protein BGM20_06285 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BGM20_06290 ENOG4105SXS Protein of unknown function (DUF456) BGM20_06305 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BGM20_06310 ENOG41063Y9 BGM20_06315 ENOG4108U5J '-nucleotidase BGM20_06320 ENOG4105N80 Ferric uptake regulator, Fur family BGM20_06325 ENOG4108JYZ YitT family BGM20_06330 ENOG41069ZM Protein of unknown function (DUF2624) BGM20_06335 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) BGM20_06350 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BGM20_06355 ENOG4105EGD dinuclear metal center protein, YbgI family BGM20_06370 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM20_06375 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BGM20_06380 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 BGM20_06385 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BGM20_06395 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BGM20_06400 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BGM20_06405 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) BGM20_06415 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BGM20_06420 ENOG4105KG3 cytidine deaminase BGM20_06425 ENOG4107YR5 Diacylglycerol kinase BGM20_06430 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BGM20_06435 ENOG4105CTJ Metal Dependent Phosphohydrolase BGM20_06445 ENOG4105C9A Phoh family BGM20_06450 ENOG4105EI1 sporulation protein yqfd BGM20_06455 ENOG41068P3 sporulation protein YqfC BGM20_06465 ENOG4105DI5 UPF0365 protein BGM20_06470 ENOG4105F7J membrane-bound serine protease BGM20_06475 ENOG4105KTH gatB Yqey BGM20_06490 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BGM20_06495 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BGM20_06500 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BGM20_06510 ENOG4105CFG Acts as a chaperone (By similarity) BGM20_06515 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BGM20_06520 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) BGM20_06525 ENOG4105CSA Coproporphyrinogen iii oxidase BGM20_06530 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BGM20_06540 ENOG4108ZRV stage ii sporulation protein p BGM20_06545 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) BGM20_06550 ENOG41082YS Binds directly to 16S ribosomal RNA BGM20_06555 ENOG4105TQK DNA polymerase iii, delta' subunit BGM20_06565 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BGM20_06570 ENOG4108UK2 deaminase BGM20_06575 ENOG4105KQC Competence protein BGM20_06585 ENOG4108D32 Methyltransferase BGM20_06595 ENOG4108WF2 Metal Dependent Phosphohydrolase BGM20_06600 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BGM20_06605 ENOG410812S Rna-binding protein BGM20_06610 ENOG4105E2X shikimate dehydrogenase BGM20_06615 ENOG4105CQW ribosome biogenesis GTPase YqeH BGM20_06620 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BGM20_06640 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BGM20_06645 ENOG41080BT SNARE associated Golgi BGM20_06660 ENOG4105WFK nuclease BGM20_06665 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM20_06670 ENOG4107Y5K Resolvase BGM20_06675 ENOG4108UXE Protein tyrosine phosphatase BGM20_06680 ENOG4105D6J arsenicaL-resistance protein BGM20_06685 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BGM20_06690 ENOG41085FC arsR family transcriptional regulator BGM20_06755 ENOG41064HX Suppressor of fused protein (SUFU) BGM20_06775 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BGM20_06810 ENOG410906S phage-like element pbsx protein xkdt BGM20_06815 ENOG41066EA baseplate J family protein BGM20_06820 ENOG4105MFU Protein of unknown function (DUF2634) BGM20_06830 ENOG4105X7F BGM20_06835 ENOG4108WZM domain protein BGM20_06840 ENOG4108FKH Transglycosylase SLT domain BGM20_06850 ENOG4105MTC XkdN-like protein BGM20_06860 ENOG4105FR7 XkdM protein, phage-like element PBSX BGM20_06865 ENOG4105PQS phage protein BGM20_06880 ENOG41060SN BGM20_06915 ENOG4106CGH Phage Mu protein F like protein BGM20_06920 ENOG4108MDF Phage Portal Protein BGM20_06925 ENOG4105IG6 Phage terminase, large subunit BGM20_06955 ENOG4105QBX endodeoxyribonuclease RusA BGM20_06980 ENOG4108PNI recT protein BGM20_06985 ENOG4108NF7 phage-type endonuclease BGM20_07010 ENOG4106A7E Transcriptional regulator BGM20_07015 ENOG41067QW Transcriptional regulator BGM20_07025 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BGM20_07045 ENOG4108SWU Histidine kinase BGM20_07050 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGM20_07055 ENOG4105DHF Membrane BGM20_07065 ENOG4108UYN gCN5-related N-acetyltransferase BGM20_07070 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BGM20_07075 ENOG41068VA BGM20_07080 ENOG41087NI Sulfite exporter TauE/SafE BGM20_07085 ENOG4105VFE sira family BGM20_07090 ENOG4107TPS domain protein BGM20_07100 ENOG4105VFE sira family BGM20_07105 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BGM20_07110 ENOG4105XTG Pfam:DUF156 BGM20_07115 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BGM20_07130 ENOG41090E6 transcriptional regulator MERR family BGM20_07145 ENOG4105C37 (CBS) domain BGM20_07160 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family BGM20_07165 ENOG4105H3G oxidoreductase BGM20_07170 ENOG4105PGM cation diffusion facilitator family transporter BGM20_07175 ENOG41090U3 tautomerase BGM20_07195 ENOG4105KMT branched-chain amino acid BGM20_07200 ENOG4108UMN azlc family BGM20_07205 ENOG4108ZRZ Transcriptional regulator (AsnC family) BGM20_07230 ENOG41064BW Protein of unknown function (DUF2568) BGM20_07240 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BGM20_07245 ENOG4105EA8 2-Nitropropane dioxygenase BGM20_07250 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BGM20_07260 ENOG4107YCY Transcriptional regulator BGM20_07270 ENOG4105CHR reductase BGM20_07275 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BGM20_07280 ENOG4108HHA Transketolase BGM20_07295 ENOG4105UNS Pfam:DUF419 BGM20_07305 ENOG4108MEK Metal-binding protein YodA BGM20_07310 ENOG410904A RNA polymerase BGM20_07315 ENOG4105CPC Aldo Keto reductase BGM20_07325 ENOG4108KAM Transcriptional regulator BGM20_07330 ENOG4105C7F AcnD-accessory protein PrpF BGM20_07335 ENOG41083Q9 chitosanase BGM20_07340 ENOG4105X5K response regulator receiver protein BGM20_07345 ENOG4108VQT Alpha beta hydrolase fold protein BGM20_07350 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein BGM20_07355 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein BGM20_07360 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase BGM20_07370 ENOG4105PGS Spore coat protein BGM20_07375 ENOG4105E2A Dehydrogenase BGM20_07390 ENOG4105VUF Transcriptional regulator BGM20_07395 ENOG4105DQ4 alcohol dehydrogenase BGM20_07400 ENOG4108Z0Z intracellular protease Pfpi family BGM20_07405 ENOG4108HKT sucrose-6-phosphate hydrolase BGM20_07410 ENOG4105F3R pts system mannose fructose sorbose family iid BGM20_07415 ENOG4105ETZ PTS System BGM20_07420 ENOG4108IQ3 PTS system BGM20_07425 ENOG4105YHU PTS system BGM20_07430 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM20_07435 ENOG4105C85 amino acid BGM20_07440 ENOG4105N14 lysine exporter protein LysE YggA BGM20_07445 ENOG4108NGU Transcriptional regulator BGM20_07450 ENOG4105JVQ RNA Polymerase BGM20_07455 ENOG4108P49 AntiSigma factor BGM20_07465 ENOG4105WDR BGM20_07470 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BGM20_07475 ENOG41082JN Transcriptional regulator BGM20_07495 ENOG4105TMB Formate nitrite transporter BGM20_07500 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BGM20_07505 ENOG4108JB9 formate dehydrogenase BGM20_07520 ENOG4105C28 cystathionine BGM20_07535 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BGM20_07550 ENOG4107XRG penicillin-binding protein BGM20_07555 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BGM20_07560 ENOG4105DBI uridine monophosphokinase BGM20_07565 ENOG4105CFP Peptidase U32 BGM20_07570 ENOG4105XYU peptidase (U32 family) BGM20_07575 ENOG4108VQJ O-methyltransferase BGM20_07580 ENOG4105HHA aminodeoxychorismate lyase BGM20_07585 ENOG4105VPH UPF0473 protein BGM20_07590 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BGM20_07595 ENOG4105VBH UPF0297 protein BGM20_07600 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BGM20_07605 ENOG4105C02 permease BGM20_07610 ENOG4105CDA abc transporter atp-binding protein BGM20_07615 ENOG4105CT1 (ABC) transporter BGM20_07620 ENOG4105EAD ABC transporter BGM20_07625 ENOG4105DRP amino acid AbC transporter BGM20_07635 ENOG41060CR BGM20_07645 ENOG4105C7H Helicase, RecD TraA family BGM20_07655 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BGM20_07660 ENOG4105C3J Cysteine desulfurase BGM20_07670 ENOG4105D1H recombination factor protein RarA BGM20_07675 ENOG4105CUZ uba thif-type nad fad binding protein BGM20_07685 ENOG4105C9M aspartyl-trna synthetase BGM20_07690 ENOG4105CUT histidyl-tRNA synthetase BGM20_07700 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BGM20_07710 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BGM20_07715 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BGM20_07720 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BGM20_07725 ENOG41067VP Protein of unknown function (DUF1049) BGM20_07730 ENOG4105NCW Trka-c domain protein BGM20_07735 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BGM20_07745 ENOG4105CKP Polysaccharide Biosynthesis Protein BGM20_07750 ENOG4108QG2 Membrane BGM20_07755 ENOG4105NAP BGM20_07760 ENOG4105VIE preprotein translocase, subunit YajC BGM20_07765 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BGM20_07770 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BGM20_07775 ENOG41061AI Protein of unknown function (DUF2905) BGM20_07780 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BGM20_07785 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BGM20_07795 ENOG4105IE8 Alpha-ketoglutarate permease BGM20_07800 ENOG4105CK5 oxidoreductase BGM20_07825 ENOG4105BZG amino acid carrier protein BGM20_07830 ENOG4105CDY transcriptional regulatory protein BGM20_07840 ENOG4106678 morphogenetic protein associated with SpoVID BGM20_07845 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BGM20_07850 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BGM20_07855 ENOG4108IYU L-aspartate oxidase BGM20_07870 ENOG4105CQC Prephenate dehydratase BGM20_07875 ENOG41090I5 UPF0735 ACT domain-containing protein BGM20_07880 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BGM20_07895 ENOG4105K46 50S ribosomal protein l27 BGM20_07900 ENOG4105X36 (ribosomal) protein BGM20_07905 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BGM20_07920 ENOG4107QMS site-determining protein BGM20_07925 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BGM20_07930 ENOG4105YHC Rod shape-determining protein MreD BGM20_07935 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BGM20_07940 ENOG4105DFF Rod shape-determining protein mreb BGM20_07945 ENOG4105W5Q DNA repair protein (RadC BGM20_07950 ENOG4108Z03 MAF-like protein BGM20_07960 ENOG4106A3R peptidase BGM20_07965 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BGM20_07970 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BGM20_07980 ENOG4106AR7 Spore coat protein BGM20_07985 ENOG41068KH stage VI sporulation protein D BGM20_07990 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BGM20_07995 ENOG4105D52 delta-aminolevulinic acid dehydratase BGM20_08005 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BGM20_08015 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) BGM20_08025 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BGM20_08030 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BGM20_08035 ENOG4108IUQ atp-dependent protease BGM20_08040 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BGM20_08045 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BGM20_08055 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BGM20_08060 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BGM20_08065 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BGM20_08070 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) BGM20_08075 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BGM20_08080 ENOG4108ZP8 Acetolactate synthase small subunit BGM20_08085 ENOG4105C7K acetolactate synthase BGM20_08095 ENOG4105I4A GCN5-related N-acetyltransferase BGM20_08105 ENOG4107KM7 Heat induced stress protein YflT BGM20_08115 ENOG4105M59 Phosphodiesterase, mj0936 family BGM20_08120 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BGM20_08125 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BGM20_08130 ENOG4108XJQ germination protein BGM20_08135 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BGM20_08140 ENOG41067TZ transcriptional regulator, MarR family BGM20_08145 ENOG4105PFC Transcriptional regulator BGM20_08155 ENOG4105E33 succinate dehydrogenase BGM20_08165 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BGM20_08180 ENOG4105CFH Aspartokinase BGM20_08185 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BGM20_08190 ENOG4105K63 Thioredoxin BGM20_08195 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BGM20_08200 ENOG4105C10 Electron transfer flavoprotein BGM20_08205 ENOG4105BZJ Electron transfer flavoprotein BGM20_08210 ENOG41060WC Enoyl-CoA hydratase BGM20_08215 ENOG4107Z3H Transcriptional regulator, TetR family BGM20_08220 ENOG4105CEY Amp-dependent synthetase and ligase BGM20_08230 ENOG4105C98 muts2 protein BGM20_08235 ENOG4105DCG PHP domain protein BGM20_08250 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BGM20_08255 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BGM20_08260 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BGM20_08270 ENOG4108RWN rrna methyltransferase BGM20_08275 ENOG41067MF small acid-soluble spore protein BGM20_08290 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BGM20_08305 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) BGM20_08310 ENOG4105DRS transport system, permease BGM20_08325 ENOG4108MDK Dehydrogenase BGM20_08335 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BGM20_08340 ENOG4105EF1 ribulokinase BGM20_08350 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase BGM20_08355 ENOG4105CN9 Peptidase m42 family protein BGM20_08365 ENOG410696E Membrane BGM20_08370 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BGM20_08375 ENOG4105VJV 50s ribosomal protein L35 BGM20_08380 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BGM20_08390 ENOG41067MG lrgb family BGM20_08400 ENOG4105DY9 regulatoR BGM20_08405 ENOG4108HRK Histidine kinase BGM20_08410 ENOG4105U0R haloacid dehalogenase-like hydrolase BGM20_08415 ENOG4105C22 threonyL-tRNA synthetase BGM20_08420 ENOG4108TDW sporulation protein YtxC BGM20_08440 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) BGM20_08445 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BGM20_08450 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BGM20_08455 ENOG4105KVH Transcriptional regulator BGM20_08460 ENOG4105F27 Major Facilitator BGM20_08465 ENOG4105CV8 reductase BGM20_08470 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BGM20_08485 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BGM20_08490 ENOG4105C2M dna polymerase I BGM20_08500 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGM20_08505 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BGM20_08510 ENOG4108HMX isocitrate dehydrogenase (NADP) BGM20_08515 ENOG4105BZN citrate synthase BGM20_08525 ENOG4108REF Sporulation integral membrane protein ytvi BGM20_08530 ENOG4105FS0 cytoplasmic membrane protein BGM20_08535 ENOG4105CA9 Pyruvate kinase BGM20_08540 ENOG4105CTQ phosphohexokinase BGM20_08550 ENOG4108IEY Carboxyl transferase domain BGM20_08555 ENOG4105C6K Malic enzyme BGM20_08560 ENOG4105C0B DNA polymerase III (alpha subunit) BGM20_08565 ENOG4105VV2 BGM20_08575 ENOG4106EVM BGM20_08580 ENOG4105SFS phosphoesterase RecJ domain protein BGM20_08600 ENOG410635A Membrane BGM20_08605 ENOG4105CH2 amidohydrolase BGM20_08625 ENOG4105DEN Luciferase family BGM20_08630 ENOG4105CDA abc transporter atp-binding protein BGM20_08655 ENOG4108XSB acetyltransferase, (GNAT) family BGM20_08660 ENOG4108KSA LysR family transcriptional regulator BGM20_08665 ENOG4105E8R UPF0173 metal-dependent hydrolase BGM20_08680 ENOG4105CH7 arginosuccinase BGM20_08685 ENOG4105CDH Citrulline--aspartate ligase BGM20_08690 ENOG4105EPU Molybdenum cofactor synthesis domain protein BGM20_08695 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BGM20_08705 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BGM20_08710 ENOG4105KBJ sporulation protein ytfj BGM20_08720 ENOG4105VK3 rdd domain containing protein BGM20_08725 ENOG4105D07 Signal peptide peptidase, SppA BGM20_08730 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BGM20_08735 ENOG4105EFZ amidohydrolase BGM20_08740 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BGM20_08775 ENOG4105U5Y Transcriptional regulator BGM20_08785 ENOG4105BZU Histidine kinase BGM20_08790 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BGM20_08800 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BGM20_08810 ENOG4105F1V Acetoin utilization protein BGM20_08815 ENOG4105W87 Cbs domain BGM20_08825 ENOG4105ER2 Ompa motb domain protein BGM20_08830 ENOG4107R0U MotA TolQ exbB proton channel BGM20_08835 ENOG4105ETE Transcriptional regulator (LacI family BGM20_08840 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BGM20_08860 ENOG4105DFU Cell wall formation (By similarity) BGM20_08870 ENOG4108VDD TRNA binding domain protein BGM20_08885 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ BGM20_08900 ENOG4105C6K Malic enzyme BGM20_08905 ENOG4105C8F Beta-lactamase domain protein BGM20_08910 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BGM20_08920 ENOG4108V15 phosphotransferase enzyme family BGM20_08925 ENOG4108IUM Glycogen debranching enzyme BGM20_08940 ENOG4107F58 2'-5' rna ligase BGM20_08945 ENOG4105C6T cysteine synthase BGM20_08955 ENOG4105C7N Xanthine uracil vitamin C permease BGM20_08970 ENOG4105YW5 deoR family transcriptional regulator BGM20_08985 ENOG4105CBX hi0933 family BGM20_08990 ENOG4105C94 Transporter BGM20_09000 ENOG4105MU9 integral membrane protein BGM20_09005 ENOG4105DDC Oxidoreductase domain protein BGM20_09015 ENOG4105F5H Glycosyl Hydrolase Family 88 BGM20_09025 ENOG41075H3 AraC family transcriptional regulator BGM20_09035 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component BGM20_09045 ENOG4106A3M Cytochrome p-450 BGM20_09050 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BGM20_09060 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BGM20_09065 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BGM20_09075 ENOG4105NTD Inherit from COG: Hydrolase BGM20_09090 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BGM20_09095 ENOG4105I1K ABC transporter BGM20_09105 ENOG41085GJ domain protein BGM20_09110 ENOG4105C8T Leucyl-tRNA synthetase BGM20_09120 ENOG4105BZU Histidine kinase BGM20_09125 ENOG410605W Major Facilitator BGM20_09130 ENOG4106UBQ BGM20_09140 ENOG4105C19 ABC transporter BGM20_09145 ENOG4105EWM Histidine kinase BGM20_09155 ENOG4107R34 abc transporter permease protein BGM20_09160 ENOG4105C19 ABC transporter BGM20_09175 ENOG4105DVE abc transporter atp-binding protein BGM20_09180 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BGM20_09195 ENOG4105N5T Radical SAM Protein BGM20_09210 ENOG4105E8V Alpha Beta Hydrolase Fold protein BGM20_09215 ENOG4108Z0R Transferase BGM20_09220 ENOG4105C85 amino acid BGM20_09225 ENOG4105CAQ asparagine synthetase BGM20_09230 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BGM20_09235 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase BGM20_09250 ENOG4105D2X ABC transporter substrate-binding protein BGM20_09260 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BGM20_09275 ENOG4108RMU ferritin dps family protein BGM20_09290 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) BGM20_09295 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BGM20_09300 ENOG4108V2W Carbonate dehydratase BGM20_09325 ENOG4105CC5 ABC transporter BGM20_09330 ENOG4105CC5 ABC transporter BGM20_09335 ENOG4105DIK (ABC) transporter BGM20_09340 ENOG4105DSE periplasmic solute binding protein BGM20_09345 ENOG4105DTQ mandelate racemase muconate lactonizing BGM20_09350 ENOG4105CEY Amp-dependent synthetase and ligase BGM20_09355 ENOG4108IPT Naphthoate synthase BGM20_09360 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BGM20_09365 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BGM20_09390 ENOG4108IAJ Nad-dependent epimerase dehydratase BGM20_09395 ENOG4107SBE Glycosyl transferase (Group 1 BGM20_09410 ENOG4107SBE Glycosyl transferase (Group 1 BGM20_09415 ENOG4108KS4 Spore coat protein BGM20_09430 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BGM20_09440 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BGM20_09575 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BGM20_09580 ENOG4105VRR gCN5-related N-acetyltransferase BGM20_09585 ENOG4105DZ6 Band 7 protein BGM20_09595 ENOG4106DF1 BGM20_09600 ENOG4108VNY MOSC domain protein BGM20_09605 ENOG4108JB8 alcohol dehydrogenase BGM20_09610 ENOG4105C26 Dehydrogenase BGM20_09615 ENOG4105TRT Transcriptional regulator BGM20_09630 ENOG4105CZN Potassium uptake protein BGM20_09635 ENOG4107I77 yiaA/B two helix domain BGM20_09640 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BGM20_09660 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BGM20_09670 ENOG4105EE0 oxidoreductase BGM20_09675 ENOG4105DKG l-rhamnose isomerase BGM20_09680 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) BGM20_09685 ENOG4105DET Rhamnulokinase BGM20_09690 ENOG4105E98 transcriptional regulator DeoR family BGM20_09700 ENOG4105C8Q Methyl-accepting chemotaxis BGM20_09705 ENOG4105C8Q Methyl-accepting chemotaxis BGM20_09710 ENOG4105C8Q Methyl-accepting chemotaxis BGM20_09730 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BGM20_09755 ENOG4107PBV potassium channel BGM20_09760 ENOG4107PBV potassium channel BGM20_09775 ENOG4107QYV phosphohexose isomerase BGM20_09785 ENOG4107QW4 alcohol dehydrogenase BGM20_09790 ENOG4105WG9 Conserved Protein BGM20_09800 ENOG4105CHM Aminotransferase BGM20_09805 ENOG4108ZB6 transcriptional regulator AsnC family BGM20_09810 ENOG4108MUZ hydrolase BGM20_09820 ENOG4105C87 Aminotransferase class I and II BGM20_09825 ENOG4108HGU Histidine kinase BGM20_09830 ENOG4105Y38 Kinase-associated protein B BGM20_09850 ENOG4105BZ4 penicillin-binding protein BGM20_09855 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BGM20_09870 ENOG4108MRH transcriptional regulatory protein BGM20_09875 ENOG4105DIH basic membrane BGM20_09880 ENOG4108JQ9 ABC transporter BGM20_09885 ENOG4105UIB (ABC) transporter BGM20_09905 ENOG4105D65 subunit l BGM20_09910 ENOG4105HC0 Na H antiporter BGM20_09915 ENOG4108ZE9 Monovalent cation H antiporter subunit C BGM20_09920 ENOG4108JPZ Monovalent cation H antiporter subunit D BGM20_09925 ENOG4105SC1 monovalent cation H antiporter subunit E BGM20_09935 ENOG4105KJM monovalent cation h antiporter subunit g BGM20_09940 ENOG4105KA0 thioesterase Superfamily protein BGM20_09950 ENOG4105BZU Histidine kinase BGM20_09975 ENOG4105D58 Diguanylate phosphodiesterase BGM20_09980 ENOG4105DAP Nicotinate phosphoribosyltransferase BGM20_10005 ENOG4105C02 permease BGM20_10025 ENOG410904N short-chain dehydrogenase reductase BGM20_10060 ENOG4108K8K Transcriptional regulator BGM20_10065 ENOG4105DCF alanine dehydrogenase BGM20_10075 ENOG4105WQT MbtH domain protein BGM20_10080 ENOG4105CEY Amp-dependent synthetase and ligase BGM20_10085 ENOG4105WQI isochorismatase BGM20_10090 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BGM20_10095 ENOG4105E4F Isochorismate synthase BGM20_10100 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BGM20_10105 ENOG4105NIV Esterase BGM20_10125 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BGM20_10135 ENOG41069ER domain protein BGM20_10150 ENOG4105CEP NADH dehydrogenase BGM20_10155 ENOG4105CAY ferredoxin--nadp reductase BGM20_10175 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BGM20_10180 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BGM20_10195 ENOG4105ZKE UPF0349 protein BGM20_10210 ENOG41083MR nifu domain-containing protein BGM20_10215 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BGM20_10220 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BGM20_10225 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) BGM20_10230 ENOG4105D6E homoserine dehydrogenase BGM20_10240 ENOG4108W5N phosphatidylglycerophosphatase a BGM20_10245 ENOG4105D4U had-superfamily hydrolase, subfamily iia BGM20_10255 ENOG4105MMD transcriptional regulator BGM20_10260 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BGM20_10265 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BGM20_10270 ENOG4105FAA peptidase M23 BGM20_10275 ENOG4108YTE sporulation protein YunB BGM20_10280 ENOG4105KZD Domain of unknown function (DUF1805) BGM20_10285 ENOG4107R8B 5'-nucleotidase BGM20_10295 ENOG4105I3N Conserved Protein BGM20_10305 ENOG4105CD3 dihydroorotase BGM20_10310 ENOG4105G9B Transcriptional regulator BGM20_10325 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) BGM20_10330 ENOG4105VT2 5-hydroxyisourate hydrolase BGM20_10340 ENOG4107YV9 domain protein BGM20_10345 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding BGM20_10360 ENOG4105XRQ Xanthine dehydrogenase accessory factor BGM20_10365 ENOG4105C5R Aminotransferase BGM20_10380 ENOG4108K8S endonuclease I BGM20_10385 ENOG4108IJ9 (ABC) transporter BGM20_10390 ENOG4105FDP GntR family transcriptional regulator BGM20_10395 ENOG4108KPW sugar kinase BGM20_10400 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BGM20_10405 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component BGM20_10410 ENOG4105XN3 extracellular solute-binding protein family 1 BGM20_10415 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine BGM20_10420 ENOG4105PKS Excinuclease abc c subunit domain protein BGM20_10425 ENOG4107VFR oxidoreductase BGM20_10440 ENOG4105DIW FeS assembly protein SUFB BGM20_10445 ENOG4108UNV SUF system FeS assembly protein, NifU family BGM20_10450 ENOG4105C9B Cysteine desulfurase BGM20_10455 ENOG4105JRK feS assembly protein SufD BGM20_10460 ENOG4105C3K feS assembly ATPase SufC BGM20_10475 ENOG4105D01 (LipO)protein BGM20_10480 ENOG4108UMI ABC transporter, permease BGM20_10485 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BGM20_10510 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BGM20_10515 ENOG41080E8 Transcriptional regulator, Spx MgsR family BGM20_10520 ENOG4105C1G acyl-Coa dehydrogenase BGM20_10525 ENOG4105CHU acetyl-coa acetyltransferase BGM20_10555 ENOG41067TZ transcriptional regulator, MarR family BGM20_10560 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGM20_10565 ENOG4105MDS 4-oxalocrotonate tautomerase BGM20_10575 ENOG4105EGI Transcriptional regulator BGM20_10585 ENOG4105E0A ABC, transporter BGM20_10600 ENOG4105E1F short-chain dehydrogenase reductase BGM20_10605 ENOG4105HUF DNA protection during starvation protein BGM20_10610 ENOG4105C0H protease BGM20_10620 ENOG4105F3H Histidine kinase BGM20_10630 ENOG41067SE Tetr family transcriptional regulator BGM20_10635 ENOG4105C9Q fumarate hydratase class II BGM20_10660 ENOG4105WH1 Two component transcriptional regulator luxr family BGM20_10665 ENOG4105ENE Histidine kinase BGM20_10680 ENOG41087YS Phage shock protein A BGM20_10695 ENOG4108WBT adenosyltransferase BGM20_10700 ENOG4105E0A ABC, transporter BGM20_10705 ENOG4105EHG Permease protein BGM20_10710 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BGM20_10715 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BGM20_10720 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BGM20_10730 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGM20_10740 ENOG4106DF4 Sigma-70, region 4 BGM20_10750 ENOG4105F0F Oxalate decarboxylase BGM20_10760 ENOG4107RBB ABC transporter, permease BGM20_10765 ENOG4105C19 ABC transporter BGM20_10770 ENOG4108WMK Efflux transporter RND family MFP subunit BGM20_10775 ENOG4105E0A ABC, transporter BGM20_10780 ENOG4105EHG Permease protein BGM20_10785 ENOG4105DQ5 transport system permease protein BGM20_10795 ENOG4105D5Q Arginine ornithine antiporter BGM20_10805 ENOG4107K5X Membrane-bound metal-dependent hydrolase BGM20_10810 ENOG4107QZ2 Sulfatase BGM20_10815 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BGM20_10820 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BGM20_10825 ENOG4105E0C molybdate abc transporter BGM20_10840 ENOG4105EEQ Na H antiporter BGM20_10845 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BGM20_10850 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BGM20_10855 ENOG4105EEM helicase BGM20_10865 ENOG4105EN6 Membrane BGM20_10875 ENOG4107ZQN disulfide bond BGM20_10880 ENOG4105C59 p-type ATPase BGM20_10885 ENOG4105C59 p-type ATPase BGM20_10890 ENOG410681U heavy metal transport detoxification protein BGM20_10895 ENOG4105VPX protein, conserved in bacteria BGM20_10900 ENOG4105D9R oxidoreductase BGM20_10905 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BGM20_10910 ENOG4105ME7 Membrane BGM20_10915 ENOG4105RXJ BGM20_10920 ENOG4105KPY Small multidrug resistance protein BGM20_10925 ENOG4105KBX Transcriptional regulator, TetR family BGM20_10930 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BGM20_10940 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BGM20_10945 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BGM20_10955 ENOG4105XZU Preprotein translocase, subunit SecG BGM20_10980 ENOG4105KVH Transcriptional regulator BGM20_10985 ENOG4105C8Q Methyl-accepting chemotaxis BGM20_10990 ENOG4105R40 Glycine betaine carnitine choline BGM20_10995 ENOG4108HQR Glycine betaine BGM20_11000 ENOG4105E90 ABC transporter BGM20_11005 ENOG4108IJ8 ABC transporter BGM20_11010 ENOG4107HG4 Transcriptional regulator BGM20_11015 ENOG4105R40 Glycine betaine carnitine choline BGM20_11020 ENOG4108HQR Glycine betaine BGM20_11025 ENOG4105E90 ABC transporter BGM20_11030 ENOG4108IJ8 ABC transporter BGM20_11035 ENOG4107HG4 Transcriptional regulator BGM20_11040 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BGM20_11045 ENOG4108QCI YvbH-like oligomerisation region BGM20_11055 ENOG4105T65 Membrane-associated protein BGM20_11060 ENOG4108W0I acetyltransferase BGM20_11065 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BGM20_11070 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BGM20_11075 ENOG4105CP7 Triose-phosphate isomerase BGM20_11080 ENOG4105BZA Phosphoglycerate kinase BGM20_11090 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BGM20_11105 ENOG4105CMD Transcriptional regulator, GntR family BGM20_11110 ENOG4105DEN Luciferase family BGM20_11120 ENOG4105GZI Transcriptional regulator BGM20_11125 ENOG4107RT3 EamA-like transporter family BGM20_11135 ENOG4105VRS hydrolase family 18 BGM20_11140 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BGM20_11145 ENOG4107QR9 Iron-sulfur cluster binding protein BGM20_11150 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BGM20_11160 ENOG4105BZU Histidine kinase BGM20_11165 ENOG4105KCT ABC transporter BGM20_11170 ENOG4108M15 ABC transporter BGM20_11175 ENOG4107R6F Alpha Beta Hydrolase Fold protein BGM20_11180 ENOG4108MJI response regulator BGM20_11195 ENOG4105EG2 ABC transporter, permease BGM20_11205 ENOG4107FKK extracellular solute-binding protein family 1 BGM20_11215 ENOG4105JXH GntR family transcriptional regulator BGM20_11220 ENOG4105DAA L-lactate BGM20_11225 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM20_11235 ENOG4108ZPC Polysaccharide pyruvyl transferase BGM20_11240 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BGM20_11245 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family BGM20_11250 ENOG4105D3Q Sugar transferase BGM20_11260 ENOG4105K64 Glycosyl transferase, family 2 BGM20_11270 ENOG4107QRS glycosyltransferase group 2 family protein BGM20_11275 ENOG41068W6 Capsular polysaccharide biosynthesis protein BGM20_11280 ENOG4108KMV Glycosyl transferase (Group 1 BGM20_11285 ENOG4105K64 Glycosyl transferase, family 2 BGM20_11290 ENOG4108PQP glycosyl transferase group 1 BGM20_11300 ENOG4108QV3 biosynthesis protein BGM20_11305 ENOG4105HTX biosynthesis protein BGM20_11315 ENOG4105EBR Carboxylesterase BGM20_11325 ENOG4105PY6 Phenolic acid decarboxylase BGM20_11330 ENOG4105NI3 Protein of unknown function (DUF3237) BGM20_11340 ENOG4105FQP Beta-lactamase BGM20_11345 ENOG4105EDQ levansucrase EC 2.4.1.10 BGM20_11350 ENOG4108HKT sucrose-6-phosphate hydrolase BGM20_11355 ENOG4107QTZ amino acid BGM20_11380 ENOG4105DNP FAD linked oxidase domain protein BGM20_11385 ENOG4105IRW patatin-like phospholipase family protein BGM20_11395 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BGM20_11400 ENOG4107URF beta-phospho-glucomutase BGM20_11405 ENOG4105CG3 alpha amylase, catalytic region BGM20_11420 ENOG4105EG2 ABC transporter, permease BGM20_11425 ENOG4105D56 permease protein BGM20_11430 ENOG4107FKK extracellular solute-binding protein family 1 BGM20_11435 ENOG4108IUK alpha amylase, catalytic BGM20_11440 ENOG4105FKQ transcriptional regulator BGM20_11445 ENOG4108URH decarboxylase BGM20_11450 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain BGM20_11455 ENOG4105CHH sulfate transporter BGM20_11460 ENOG4108V2W Carbonate dehydratase BGM20_11465 ENOG4105C5I Dehydrogenase BGM20_11475 ENOG4105C19 ABC transporter BGM20_11480 ENOG4105EWM Histidine kinase BGM20_11490 ENOG4107A6P BGM20_11495 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BGM20_11500 ENOG4105KRI phosphocarrier protein (HPr BGM20_11505 ENOG4105CIE May be required for sporulation (By similarity) BGM20_11510 ENOG4105CHW UPF0052 protein BGM20_11515 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BGM20_11520 ENOG4108Z4K mutator MutT protein BGM20_11525 ENOG4105C3M thioredoxin reductase BGM20_11540 ENOG4105BZ1 (ABC) transporter BGM20_11550 ENOG4106FGC BGM20_11560 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BGM20_11565 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BGM20_11570 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BGM20_11575 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BGM20_11580 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BGM20_11585 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BGM20_11590 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BGM20_11595 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) BGM20_11605 ENOG4108E16 pectate lyase BGM20_11610 ENOG4108S4C acetyltransferase BGM20_11615 ENOG4107XGZ Hydrolase BGM20_11620 ENOG4105HKU nucleoside recognition domain-containing protein BGM20_11625 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) BGM20_11630 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) BGM20_11635 ENOG4105CE4 GlcNAc 6-P deacetylase BGM20_11640 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BGM20_11645 ENOG4105FDP GntR family transcriptional regulator BGM20_11650 ENOG41088CQ domain protein BGM20_11660 ENOG4106A3M Cytochrome p-450 BGM20_11665 ENOG410625E BGM20_11680 ENOG41086DT Membrane protein of unknown function BGM20_11685 ENOG41067S9 phage shock protein C, PspC BGM20_11690 ENOG4108PY7 BGM20_11705 ENOG4105I03 Flagellin BGM20_11710 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BGM20_11715 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BGM20_11730 ENOG4105MKU Transcriptional regulator BGM20_11750 ENOG4105CN1 protease BGM20_11755 ENOG4105CRP Part of the ABC transporter FtsEX involved in BGM20_11760 ENOG4105CAK Cell division ATP-binding protein ftsE BGM20_11775 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BGM20_11785 ENOG4105MS2 ribosomal subunit Interface protein BGM20_11800 ENOG4105MQ3 flagellar protein FliS BGM20_11805 ENOG4107RT6 flagellar hook-associated BGM20_11810 ENOG41083S7 flagellar protein FlaG BGM20_11815 ENOG4105I03 Flagellin BGM20_11820 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BGM20_11825 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) BGM20_11830 ENOG4105MKD BGM20_11835 ENOG4105DTJ flagellar hook-associated protein BGM20_11840 ENOG4105E1Q flagellar hook-associated protein BGM20_11855 ENOG4105RU3 BGM20_11860 ENOG41081UC Inherit from COG: Competence protein BGM20_11880 ENOG4105WH1 Two component transcriptional regulator luxr family BGM20_11885 ENOG4105BZU Histidine kinase BGM20_11890 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BGM20_11895 ENOG4108KGH TRANSCRIPTIONal BGM20_11900 ENOG4105ESV Glycosyl transferase, family 4 BGM20_11905 ENOG4107EF8 Glycosyl transferase (Group 1 BGM20_11920 ENOG4105QZI O-Antigen Polymerase BGM20_11925 ENOG4105C6Y Udp-glucose 6-dehydrogenase BGM20_11930 ENOG4107RA4 Glycosyl transferase (Group 1 BGM20_11935 ENOG4105PSV Polysaccharide Biosynthesis Protein BGM20_11940 ENOG4105D3Q Sugar transferase BGM20_11950 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BGM20_11955 ENOG4105JFG SpoIID LytB domain protein BGM20_11970 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BGM20_11990 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BGM20_11995 ENOG4105EY8 ABC transporter BGM20_12015 ENOG4107VDP teichoic acid biosynthesis BGM20_12020 ENOG41088M2 Glycosyl transferase family 2 BGM20_12070 ENOG4105DG6 mannose-6-phosphate isomerase BGM20_12090 ENOG4108NHD germination protein BGM20_12095 ENOG4105C54 Major Facilitator superfamily BGM20_12100 ENOG4108KGH TRANSCRIPTIONal BGM20_12105 ENOG4105J7I hydrolase BGM20_12110 ENOG4105K4H Nlp p60 protein BGM20_12120 ENOG4105PNM synthesis protein BGM20_12130 ENOG4105N98 Capsule biosynthesis protein capB BGM20_12135 ENOG4105ETE Transcriptional regulator (LacI family BGM20_12140 ENOG4108RVA ribokinase BGM20_12145 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BGM20_12150 ENOG4105C2J ABC transporter BGM20_12155 ENOG4105CNN ABC, transporter BGM20_12160 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BGM20_12175 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BGM20_12180 ENOG4107FQX Alpha-acetolactate decarboxylase BGM20_12190 ENOG4107RSM transcriptional regulator BGM20_12205 ENOG4106UIA BGM20_12220 ENOG4107XC4 flavin reductase domain protein, FMN-binding BGM20_12230 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BGM20_12240 ENOG4105CAH Chromate BGM20_12245 ENOG4105FGV Chromate BGM20_12255 ENOG4108WS4 fmn reductase BGM20_12260 ENOG4107V2S Transcriptional regulator BGM20_12265 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BGM20_12305 ENOG4108XI2 Domain of unknown function (DUF1963) BGM20_12310 ENOG4105C6Y Udp-glucose 6-dehydrogenase BGM20_12315 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BGM20_12320 ENOG4107YJ4 chain length determinant protein BGM20_12325 ENOG4105HTX biosynthesis protein BGM20_12335 ENOG4105KBK Zinc finger, swim domain protein BGM20_12340 ENOG4105C0D helicase BGM20_12345 ENOG410667J hydrolase BGM20_12350 ENOG4105E98 transcriptional regulator DeoR family BGM20_12355 ENOG4105Z8H single-stranded DNA-binding protein BGM20_12380 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) BGM20_12385 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BGM20_12395 ENOG4105CGA flagellar basal-body rod protein FlgG BGM20_12405 ENOG4105DFF Rod shape-determining protein mreb BGM20_12410 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BGM20_12415 ENOG4107MII Sugar-specific transcriptional regulator TrmB BGM20_12420 ENOG4105CZM Major Facilitator BGM20_12425 ENOG4108M26 parallel beta-helix repeat protein BGM20_12430 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BGM20_12435 ENOG41080V3 Major Facilitator superfamily BGM20_12440 ENOG4105D3W isochorismatase BGM20_12445 ENOG4107P26 BGM20_12450 ENOG4105BZU Histidine kinase BGM20_12460 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BGM20_12470 ENOG4105FRN stage II sporulation protein BGM20_12475 ENOG4107TCE N-acetyltransferase BGM20_12495 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BGM20_12500 ENOG4107TXC Transcriptional regulator BGM20_12505 ENOG4106BRK BGM20_12510 ENOG4108RYK Nad-dependent epimerase dehydratase BGM20_12515 ENOG4108Z40 Transcriptional regulator BGM20_12520 ENOG4105CQM Urea amidohydrolase subunit alpha BGM20_12525 ENOG4105KI2 Urea amidohydrolase subunit beta BGM20_12530 ENOG4108YZ9 Urea amidohydrolase subunit gamma BGM20_12565 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BGM20_12575 ENOG4108TF4 von Willebrand factor, type A BGM20_12590 ENOG4105JFG SpoIID LytB domain protein BGM20_12595 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BGM20_12605 ENOG4106778 Protein of unknown function (DUF1146) BGM20_12615 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BGM20_12620 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BGM20_12625 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BGM20_12630 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BGM20_12655 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) BGM20_12665 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BGM20_12670 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BGM20_12675 ENOG4108UIC UPF0340 protein BGM20_12680 ENOG4108YZG isomerase BGM20_12685 ENOG4107WAU Protein tyrosine phosphatase BGM20_12690 ENOG410815N Probably functions as a manganese efflux pump (By similarity) BGM20_12695 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BGM20_12705 ENOG4108ZXQ stage ii sporulation protein r BGM20_12725 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BGM20_12730 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BGM20_12740 ENOG4107TT2 Auxin Efflux Carrier BGM20_12745 ENOG4105C6K Malic enzyme BGM20_12750 ENOG4107104 thymidine kinase BGM20_12755 ENOG41082DI 50s ribosomal protein l31 BGM20_12770 ENOG4105CBT Fructose-1,6-bisphosphatase BGM20_12775 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BGM20_12780 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway BGM20_12785 ENOG4105D2N Aldolase BGM20_12790 ENOG410812K response regulator receiver protein BGM20_12800 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BGM20_12815 ENOG4105DF6 Fe-S oxidoreductase BGM20_12825 ENOG4105E5J UV damage endonuclease BGM20_12835 ENOG4105NAE bifunctional deaminase-reductase domain protein BGM20_12840 ENOG4105BZ1 (ABC) transporter BGM20_12845 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BGM20_12860 ENOG4105R3A Nitrate reductase BGM20_12865 ENOG4108IUE nitrate reductase beta subunit BGM20_12885 ENOG4107V6Q Cyclic nucleotide-binding domain BGM20_12895 ENOG4105C75 arginyL-tRNA synthetase BGM20_12900 ENOG410684U Domain of unknown function (DUF1934) BGM20_12910 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E BGM20_12960 ENOG4107JM4 Tetratricopeptide repeat BGM20_12990 ENOG4108RDQ ABC transporter BGM20_13000 ENOG4105CYW agmatinase BGM20_13005 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BGM20_13010 ENOG4105BZ4 penicillin-binding protein BGM20_13015 ENOG4108XFG YwhD family BGM20_13020 ENOG4108Z4T Peptidase M50 BGM20_13025 ENOG41069HH 4-oxalocrotonate tautomerase BGM20_13030 ENOG41067TZ transcriptional regulator, MarR family BGM20_13035 ENOG4105C22 threonyL-tRNA synthetase BGM20_13045 ENOG4105C57 major facilitator superfamily BGM20_13050 ENOG41062ES Transcriptional regulator BGM20_13060 ENOG4105DCI Phosphohydrolase BGM20_13070 ENOG4108VCI transcription factor, rsfa family BGM20_13075 ENOG4108RNG Permease of the drug metabolite transporter BGM20_13080 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BGM20_13085 ENOG4105DUM transcriptional regulator, lysR family BGM20_13090 ENOG4108IJ2 phosphate acetyltransferase BGM20_13105 ENOG4105CHM Aminotransferase BGM20_13115 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase BGM20_13120 ENOG4105CHR reductase BGM20_13125 ENOG4106CHD Bacilysin biosynthesis protein bacB BGM20_13130 ENOG41061WN bacilysin biosynthesis protein BGM20_13135 ENOG4105FCW Major Facilitator superfamily BGM20_13150 ENOG4105C26 Dehydrogenase BGM20_13155 ENOG4105D82 Glutamate dehydrogenase BGM20_13165 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase BGM20_13170 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BGM20_13175 ENOG4105C1B dTDP-glucose 4-6-dehydratase BGM20_13180 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BGM20_13185 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG BGM20_13190 ENOG4107TY6 Acylneuraminate cytidylyltransferase BGM20_13200 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD BGM20_13205 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BGM20_13245 ENOG4105C26 Dehydrogenase BGM20_13250 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BGM20_13255 ENOG4108RJ9 Glycosyl transferase, family 2 BGM20_13260 ENOG4105DWF phosphomethylpyrimidine kinase BGM20_13275 ENOG4105C5Y PTS System BGM20_13280 ENOG4108QTI )-transporter BGM20_13295 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BGM20_13300 ENOG4105DEN Luciferase family BGM20_13305 ENOG4108DBC nitroreductase BGM20_13320 ENOG41060D1 Quinol oxidase BGM20_13325 ENOG4105CCU oxidase (Subunit III) BGM20_13330 ENOG4105BZ9 Cytochrome C oxidase, subunit I BGM20_13335 ENOG4105E2S oxidase) subunit II BGM20_13340 ENOG4107BMA Transglycosylase associated protein BGM20_13350 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BGM20_13355 ENOG4105WH5 Teichoic acid glycosylation protein BGM20_13380 ENOG4107ZXU DSBA oxidoreductase BGM20_13385 ENOG4105DBE peroxidase BGM20_13390 ENOG410650H (LipO)protein BGM20_13395 ENOG4107SJW iron permease, FTR1 BGM20_13400 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BGM20_13410 ENOG4105CMU LysR family (Transcriptional regulator BGM20_13415 ENOG4105VAW lrga family BGM20_13420 ENOG41067MG lrgb family BGM20_13425 ENOG4105D8G Major Facilitator superfamily BGM20_13435 ENOG4105DR4 Methyltransferase BGM20_13445 ENOG4105CK1 PTS System BGM20_13455 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin BGM20_13470 ENOG4105X1N Glycosyl transferase family 8 BGM20_13480 ENOG4105GVJ transcriptional regulator BGM20_13485 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BGM20_13490 ENOG4105IIU Aminopeptidase BGM20_13515 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BGM20_13530 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) BGM20_13535 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BGM20_13545 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BGM20_13550 ENOG4108VHC Short-chain dehydrogenase reductase Sdr BGM20_13555 ENOG4105CM2 brancheD-chain amino acid aminotransferase BGM20_13560 ENOG4105F8D glycoside hydrolase family 4 BGM20_13565 ENOG4105VCP PTS System BGM20_13570 ENOG4105CK1 PTS System BGM20_13575 ENOG4105VZJ PTS System BGM20_13580 ENOG4105EMD TRANSCRIPTIONal BGM20_13590 ENOG4108VX5 3-methyladenine DNA glycosylase BGM20_13595 ENOG4105CH6 catalase BGM20_13610 ENOG4105DA5 (ABC) transporter BGM20_13615 ENOG41069JR BGM20_13635 ENOG4105ETS cytosine purines uracil thiamine allantoin BGM20_13640 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BGM20_13650 ENOG4108JJ9 ABC, transporter BGM20_13655 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BGM20_13660 ENOG4105C4M (Ubiquinol oxidase) subunit I BGM20_13665 ENOG4105D2K citrate carrier protein BGM20_13680 ENOG4107BJW polysaccharide deacetylase BGM20_13700 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BGM20_13710 ENOG4105CMR udp-glucose 4-epimerase BGM20_13720 ENOG4105BZU Histidine kinase BGM20_13725 ENOG4105WH1 Two component transcriptional regulator luxr family BGM20_13730 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BGM20_13760 ENOG4105DTD Dehydrogenase BGM20_13765 ENOG4108IIH CoA-transferase subunit B BGM20_13770 ENOG4105D6N CoA-transferase, subunit a BGM20_13775 ENOG4105CY2 Citrate transporter BGM20_13780 ENOG4105DHI Methyltransferase BGM20_13800 ENOG4105CH6 catalase BGM20_13805 ENOG4105D4T Citrate transporter BGM20_13810 ENOG4108RZ2 Glycoside hydrolase family 16 BGM20_13815 ENOG4105CID antiterminator BGM20_13825 ENOG4105DEU major facilitator superfamily BGM20_13830 ENOG4105C1J atp-dependent rna helicase BGM20_13885 ENOG4105CNA YD repeat protein BGM20_13895 ENOG4107YZX Universal stress protein BGM20_13900 ENOG4105CS2 ec 3.2.1.21 BGM20_13905 ENOG4105C5Y PTS System BGM20_13920 ENOG4107EV6 Inherit from COG: YD repeat protein BGM20_13935 ENOG4106Z5D Glycoside Hydrolase Family 43 BGM20_13950 ENOG4105C84 Histidine ammonia-lyase BGM20_13955 ENOG4105CGP Urocanate hydratase BGM20_13960 ENOG4105CI2 imidazolone-5-propionate hydrolase BGM20_13965 ENOG4107W25 arginase agmatinase formiminoglutamase BGM20_13975 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BGM20_13980 ENOG4105D9N nucleoside BGM20_13990 ENOG4107RHR regulatoR BGM20_13995 ENOG4108TM9 integral membrane protein BGM20_14000 ENOG4105ENY Ethanolamine utilization protein eutH BGM20_14005 ENOG4108PGP mmge prpd family protein BGM20_14010 ENOG4105CH2 amidohydrolase BGM20_14020 ENOG4108HW4 amino acid AbC transporter BGM20_14025 ENOG4105EAB amino acid AbC transporter BGM20_14030 ENOG4108XSB acetyltransferase, (GNAT) family BGM20_14035 ENOG4105CPU Monooxygenase BGM20_14040 ENOG4107QHE Choloylglycine hydrolase BGM20_14045 ENOG410667J hydrolase BGM20_14075 ENOG4108V5C ABC transporter BGM20_14105 ENOG4105D2N Aldolase BGM20_14110 ENOG4107TRN Xylose isomerase domain protein TIM barrel BGM20_14115 ENOG4105F0H myo-inositol catabolism protein BGM20_14120 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BGM20_14130 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BGM20_14135 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BGM20_14140 ENOG4105D7K pfkb domain protein BGM20_14145 ENOG4105DH8 myo-inositol catabolism BGM20_14150 ENOG4105C26 Dehydrogenase BGM20_14160 ENOG4105CPC Aldo Keto reductase BGM20_14175 ENOG4107QNK )-transporter BGM20_14180 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BGM20_14190 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BGM20_14195 ENOG4105ST3 Transcriptional regulator BGM20_14200 ENOG4105C26 Dehydrogenase BGM20_14210 ENOG4108ITS PQQ enzyme repeat BGM20_14220 ENOG41085PJ rdd domain containing protein BGM20_14235 ENOG4105J7D transcriptional regulator BGM20_14240 ENOG4107JEE Short-chain dehydrogenase reductase Sdr BGM20_14245 ENOG41061AU MarR family Transcriptional regulator BGM20_14265 ENOG4105BZW Glycerate kinase BGM20_14270 ENOG4105G3Z GntR family transcriptional regulator BGM20_14275 ENOG4105CMG Carbohydrate kinase BGM20_14280 ENOG4105C6Z Gluconate BGM20_14285 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BGM20_14290 ENOG4105D3R alkyl hydroperoxide reductase BGM20_14295 ENOG4108JU3 Alkyl hydroperoxide reductase BGM20_14300 ENOG4105CS2 ec 3.2.1.21 BGM20_14310 ENOG4108S3Y transcriptional regulator BGM20_14315 ENOG4106KKU BGM20_14320 ENOG4108Z15 abc transporter atp-binding protein BGM20_14325 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 BGM20_14340 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BGM20_14355 ENOG4105E2A Dehydrogenase BGM20_14375 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BGM20_14380 ENOG4105WQG acetyltransferase BGM20_14385 ENOG410780I phosphoprotein phosphatase activity BGM20_14395 ENOG41066UZ arginase EC 3.5.3.1 BGM20_14400 ENOG4108IQI permease BGM20_14405 ENOG4105C8Y Acetylornithine aminotransferase BGM20_14410 ENOG4108JUB Transcriptional regulator BGM20_14415 ENOG4105BZU Histidine kinase BGM20_14440 ENOG4105C0H protease BGM20_14445 ENOG4105Q2H domain protein BGM20_14460 ENOG4105BZU Histidine kinase BGM20_14465 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGM20_14490 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BGM20_14495 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BGM20_14500 ENOG4105CDU Replicative dna helicase BGM20_14525 ENOG4105DJ2 Major Facilitator Superfamily BGM20_14530 ENOG4105EDW glycosyl transferase, family 39 BGM20_14535 ENOG4105K9Q Binds to the 23S rRNA (By similarity) BGM20_14540 ENOG4105BZR domain protein BGM20_14545 ENOG4108XMW Membrane BGM20_14560 ENOG4105KVH Transcriptional regulator BGM20_14565 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BGM20_14585 ENOG41090E6 transcriptional regulator MERR family BGM20_14595 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein BGM20_14600 ENOG4105DDN Pentapeptide repeat-containing protein BGM20_14605 ENOG4105D94 Major Facilitator Superfamily BGM20_14615 ENOG41082BV acetyltransferase BGM20_14620 ENOG41081I9 integral membrane protein BGM20_14630 ENOG4108U05 Transcriptional regulator BGM20_14635 ENOG41082BV acetyltransferase BGM20_14645 ENOG4108U7W acetyltransferase BGM20_14650 ENOG4105UNS Pfam:DUF419 BGM20_14655 ENOG4105NAE bifunctional deaminase-reductase domain protein BGM20_14665 ENOG4105C7Z Conserved Protein BGM20_14670 ENOG4107FCW Abortive infection protein BGM20_14680 ENOG4108UW5 maltose o-acetyltransferase BGM20_14685 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BGM20_14695 ENOG4105CGK Exodeoxyribonuclease III BGM20_14700 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BGM20_14705 ENOG4108UUM single-stranded DNA-binding protein BGM20_14710 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BGM20_14715 ENOG4105C3G gtp-binding protein BGM20_14720 ENOG4108J2R molybdopterin oxidoreductase BGM20_14725 ENOG4105VDK protein, conserved in bacteria BGM20_14735 ENOG4108ZDA Sporulation protein YyaC BGM20_14740 ENOG4105FA0 parb-like partition protein BGM20_14745 ENOG4107QJE Chromosome Partitioning Protein BGM20_14760 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) BGM20_14765 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BGM20_14770 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BGM20_14785 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) BGM20_14795 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BGM20_14800 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BGM20_14805 ENOG410848D S4 domain protein YaaA BGM20_14820 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGM20_14825 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGM20_14860 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BGM20_14870 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) BGM20_14875 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) BGM20_14880 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BGM20_14890 ENOG4105ZMH deoxynucleoside kinase BGM20_14900 ENOG4105VRS hydrolase family 18 BGM20_14905 ENOG4105GTG Isochorismatase BGM20_14910 ENOG4108Z6B deaminase BGM20_14920 ENOG4105C6E dna polymerase iii BGM20_14925 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BGM20_14930 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BGM20_14940 ENOG41067KS pro-sigma K processing BGM20_14980 ENOG4105CDW Resistance protein BGM20_14985 ENOG4105CXN decarboxylase BGM20_14990 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BGM20_14995 ENOG4105X0R protein from nitrogen regulatory protein P-II BGM20_15000 ENOG4105XVJ Protein of unknown function (DUF327) BGM20_15005 ENOG4105FA2 dna polymerase iii BGM20_15010 ENOG4105MA4 psp1 domain protein BGM20_15015 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) BGM20_15020 ENOG41060K3 Methyltransferase BGM20_15025 ENOG4105VC4 domain protein BGM20_15030 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BGM20_15035 ENOG4105KRN Transcriptional regulator, abrb family BGM20_15040 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BGM20_15045 ENOG4105F8V Hydrolase, tatD family BGM20_15050 ENOG41069ER domain protein BGM20_15060 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BGM20_15065 ENOG4105XFA sporulation peptidase YabG BGM20_15070 ENOG4105W42 Veg protein BGM20_15075 ENOG4105XEW small acid-soluble spore protein BGM20_15080 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BGM20_15085 ENOG4105DFT pur operon repressor BGM20_15090 ENOG4105KME endoribonuclease L-psp BGM20_15095 ENOG4105K4W Could be involved in septation (By similarity) BGM20_15105 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BGM20_15110 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BGM20_15115 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BGM20_15120 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BGM20_15130 ENOG4108JA2 transcriptioN-repair coupling factor BGM20_15135 ENOG4108M14 stage v sporulation protein t BGM20_15145 ENOG4108IY2 MazG family BGM20_15150 ENOG41082I2 s4 domain protein BGM20_15155 ENOG4105VYY sporulation protein yabp BGM20_15170 ENOG41060GV RNA binding s1 domain protein BGM20_15200 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BGM20_15205 ENOG4108UGV hypoxanthine phosphoribosyltransferase BGM20_15210 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BGM20_15220 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BGM20_15225 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase BGM20_15230 ENOG4105C6T cysteine synthase BGM20_15235 ENOG4105CRQ synthase (Component I) BGM20_15240 ENOG4105DDQ anthranilate synthase BGM20_15245 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BGM20_15250 ENOG4105EEI dihydropteroate synthase BGM20_15255 ENOG4105KRF dihydroneopterin aldolase BGM20_15260 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BGM20_15270 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BGM20_15275 ENOG4105CRK lysyL-tRNA synthetase BGM20_15365 ENOG4108Z0C Uvrb UvrC protein BGM20_15370 ENOG41066A3 ATP guanido phosphotransferase BGM20_15380 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BGM20_15385 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BGM20_15390 ENOG4105CTP PilT protein domain protein BGM20_15395 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BGM20_15400 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BGM20_15405 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BGM20_15415 ENOG4105D7W serine acetyltransferase BGM20_15420 ENOG4105C8N cysteinyl-tRNA synthetase BGM20_15425 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) BGM20_15430 ENOG4105C2N RNA methyltransferase TrmH family group 3 BGM20_15435 ENOG4105M0M Tetracycline resistance protein BGM20_15455 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BGM20_15460 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BGM20_15470 ENOG4108VZM 50s ribosomal protein L10 BGM20_15475 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BGM20_15480 ENOG4107Y49 methyltransferase BGM20_15485 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BGM20_15490 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BGM20_15495 ENOG4105XPM ribosomal protein BGM20_15500 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) BGM20_15505 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BGM20_15510 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BGM20_15515 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BGM20_15520 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BGM20_15525 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) BGM20_15530 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BGM20_15535 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BGM20_15540 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BGM20_15545 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BGM20_15550 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BGM20_15555 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BGM20_15560 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BGM20_15565 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BGM20_15570 ENOG41082SA 50s ribosomal protein l29 BGM20_15575 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BGM20_15580 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) BGM20_15590 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BGM20_15600 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BGM20_15605 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BGM20_15610 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) BGM20_15615 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BGM20_15620 ENOG4105VPB 50S ribosomal protein L30 BGM20_15630 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BGM20_15640 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BGM20_15650 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BGM20_15660 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BGM20_15665 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) BGM20_15670 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BGM20_15675 ENOG4108ZT0 50S ribosomal protein l17 BGM20_15680 ENOG4108JJB ABC transporter BGM20_15685 ENOG4108JJB ABC transporter BGM20_15690 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BGM20_15695 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BGM20_15700 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BGM20_15705 ENOG4108UJD 30S ribosomal protein S9 BGM20_15710 ENOG4108I0C methyltransferase BGM20_15725 ENOG4105D1F ATP-binding protein BGM20_15740 ENOG4108NMV polysaccharide deacetylase BGM20_15825 ENOG4105CHH sulfate transporter BGM20_15835 ENOG4108SA1 esterase BGM20_15855 ENOG410874W AraC family transcriptional regulator BGM20_15860 ENOG4105EHZ conserved protein UCP016719 BGM20_15865 ENOG4105D17 glycoside hydrolase, family 3 domain protein BGM20_15885 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BGM20_15895 ENOG4105EWC Purine nucleoside phosphorylase BGM20_15925 ENOG4105EMN RNA polymerase sigma factor BGM20_15935 ENOG4105C8B TIGR00159 family BGM20_15940 ENOG4107U5W ybbr family BGM20_15945 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BGM20_15950 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BGM20_15955 ENOG4105D03 DNA-3-methyladenine glycosylase II BGM20_15970 ENOG4108TWJ NADH dehydrogenase subunit 5 BGM20_15990 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BGM20_16000 ENOG4105WAB arsR family transcriptional regulator BGM20_16005 ENOG4108RWP Major Facilitator Superfamily protein BGM20_16020 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BGM20_16040 ENOG4105BZ1 (ABC) transporter BGM20_16065 ENOG4105G0J serine threonine protein kinase BGM20_16075 ENOG4106K80 BGM20_16085 ENOG4106DDH Sporulation-specific SASP protein BGM20_16095 ENOG4108HWY Beta-lactamase BGM20_16100 ENOG4107E6A Cytochrome p-450 BGM20_16110 ENOG4107QTZ amino acid BGM20_16115 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BGM20_16120 ENOG4105CXY transporter BGM20_16130 ENOG410645S MarR family Transcriptional regulator BGM20_16135 ENOG4105DCM major facilitator superfamily BGM20_16150 ENOG410631K Membrane BGM20_16155 ENOG4106AXJ AraC family transcriptional regulator BGM20_16160 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BGM20_16165 ENOG4108TCS Glutamyl endopeptidase BGM20_16175 ENOG4108WC5 Alpha Beta Hydrolase Fold protein BGM20_16180 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BGM20_16185 ENOG4107ZTW SNARE associated Golgi BGM20_16200 ENOG4105C72 UPF0176 protein BGM20_16210 ENOG4108IIZ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane BGM20_16215 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BGM20_16220 ENOG4108X79 transcriptional regulator BGM20_16230 ENOG4105CM2 brancheD-chain amino acid aminotransferase BGM20_16235 ENOG4108IQI permease BGM20_16240 ENOG4108J5H Homocysteine s-methyltransferase BGM20_16255 ENOG4105CSV Glutaminase BGM20_16270 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase BGM20_16275 ENOG4105C26 Dehydrogenase BGM20_16280 ENOG4105DJB Major Facilitator Superfamily BGM20_16285 ENOG4105EQX glucarate dehydratase BGM20_16290 ENOG41073TP transcriptional regulator BGM20_16295 ENOG4105CTX dehydratase BGM20_16315 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGM20_16350 ENOG4105MUA Resistance protein BGM20_16360 ENOG4105DGI Alkaline phosphatase BGM20_16365 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BGM20_16370 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BGM20_16375 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BGM20_16380 ENOG4107EPV Aminotransferase class V BGM20_16385 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGM20_16390 ENOG4105J7D transcriptional regulator BGM20_16395 ENOG4107RB3 L-asparaginase BGM20_16400 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BGM20_16410 ENOG41060AI SEC-C motif BGM20_16420 ENOG4107Y7X LytTR BGM20_16425 ENOG4108IUW ABC transporter BGM20_16430 ENOG4108SDH ABC, transporter BGM20_16435 ENOG4107SET aldo keto reductase BGM20_16465 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BGM20_16475 ENOG4105DSE periplasmic solute binding protein BGM20_16480 ENOG4105DIK (ABC) transporter BGM20_16490 ENOG4105DEN Luciferase family BGM20_16495 ENOG4108N0M stress protein BGM20_16500 ENOG4106FN3 tellurium resistance protein BGM20_16505 ENOG4106FN3 tellurium resistance protein BGM20_16510 ENOG4107TS3 membrane protein, TerC BGM20_16515 ENOG4108TTB tellurium resistance protein BGM20_16525 ENOG41079KZ Major Facilitator Superfamily BGM20_16530 ENOG4107XZQ multidrug resistance protein BGM20_16535 ENOG4108A65 Transcriptional regulator BGM20_16540 ENOG4108IJ7 Glycine betaine BGM20_16545 ENOG4107SQ8 Glycine betaine BGM20_16580 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BGM20_16615 ENOG4105EIG urea carboxylase-associated protein 1 BGM20_16620 ENOG4107RA1 nh(3)-dependent nad( ) synthetase BGM20_16625 ENOG4105I1F Resistance protein BGM20_16635 ENOG41089UC methyltransferase, type 11 BGM20_16640 ENOG4105C5Q Transcriptional regulator BGM20_16645 ENOG4105I82 acetyl xylan esterase BGM20_16650 ENOG410756H nucleotidyltransferase BGM20_16660 ENOG4105C26 Dehydrogenase BGM20_16665 ENOG4105CK7 Sodium proline symporter BGM20_16670 ENOG4107YHD transcriptional regulator BGM20_16680 ENOG4108PJD permease BGM20_16685 ENOG4105U6C Alpha beta hydrolase fold protein BGM20_16695 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BGM20_16700 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BGM20_16705 ENOG4108IFG nitrite reductase, (NAD(P)H) BGM20_16710 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BGM20_16730 ENOG4105S7A ErfK ybiS ycfS ynhG family protein BGM20_16740 ENOG4105CKI cobalamin synthesis protein BGM20_16745 ENOG4105E5Q amino acid AbC transporter BGM20_16750 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein BGM20_16760 ENOG4105HHM rdd domain containing protein BGM20_16770 ENOG4105CS2 ec 3.2.1.21 BGM20_16785 ENOG4105C8Q Methyl-accepting chemotaxis BGM20_16790 ENOG41080HJ 6-phospho 3-hexuloisomerase BGM20_16795 ENOG4108VA3 3-hexulose-6-phosphate synthase BGM20_16800 ENOG4105KVH Transcriptional regulator BGM20_16810 ENOG4105CEY Amp-dependent synthetase and ligase BGM20_16840 ENOG4105SX7 Transporter BGM20_16850 ENOG4105W8Z 4'-phosphopantetheinyl transferase BGM20_16860 ENOG4105CDA abc transporter atp-binding protein BGM20_16865 ENOG4105DRP amino acid AbC transporter BGM20_16875 ENOG4106P55 Transcriptional regulator BGM20_16880 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BGM20_16885 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BGM20_16890 ENOG41069ZX BGM20_16895 ENOG41069ZX BGM20_16905 ENOG4105DUX Transporter BGM20_16920 ENOG4105E1K spore germination protein BGM20_16940 ENOG4107WD8 ABC transporter, permease BGM20_16945 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGM20_16950 ENOG4105BZU Histidine kinase BGM20_16970 ENOG4105CFH Aspartokinase BGM20_16975 ENOG4105DHS permease protein BGM20_16980 ENOG4105CM4 permease protein BGM20_16985 ENOG4108IPW abc transporter atp-binding protein BGM20_17000 ENOG4105R8C Transcriptional regulator BGM20_17005 ENOG4108DBC nitroreductase BGM20_17010 ENOG41067V3 Antibiotic biosynthesis monooxygenase BGM20_17015 ENOG4105YVS arsR family transcriptional regulator BGM20_17025 ENOG4108JPW Aminotransferase BGM20_17030 ENOG4105C26 Dehydrogenase BGM20_17040 ENOG4105H9W Short-chain dehydrogenase reductase Sdr BGM20_17045 ENOG4105KTB nuclear export factor GLE1 BGM20_17050 ENOG4108T5E Copper resistance protein BGM20_17055 ENOG4108ZYE Transcriptional regulator BGM20_17080 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BGM20_17085 ENOG4108ZX0 Signal peptidase I BGM20_17115 ENOG4105E7W lamb ycsf family protein BGM20_17120 ENOG4105C5A transporter BGM20_17125 ENOG4105CFM UPF0317 protein BGM20_17130 ENOG4105P4J Allophanate hydrolase, subunit 1 BGM20_17140 ENOG4107258 Transcriptional regulator BGM20_17145 ENOG4105XJB lipolytic protein G-D-S-L family BGM20_17155 ENOG41061CK Antibiotic biosynthesis monooxygenase BGM20_17160 ENOG4107RVG penicillin-binding protein BGM20_17165 ENOG4107QM2 Aldo Keto reductase BGM20_17170 ENOG4105ETD TRANSCRIPTIONal BGM20_17180 ENOG4105HMZ Methyltransferase BGM20_17185 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BGM20_17200 ENOG410606W general stress protein BGM20_17210 ENOG4105VCH membrane BGM20_17220 ENOG4105C9U ATP-dependent DNA helicase RecQ BGM20_17235 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BGM20_17240 ENOG4107R8N Glycosyl transferase, family 2 BGM20_17250 ENOG4105C0X amino acid BGM20_17270 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BGM20_17280 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) BGM20_17285 ENOG4105EU9 BGM20_17290 ENOG4105QVS general stress protein BGM20_17295 ENOG41082W1 Cupin 2, conserved barrel domain protein BGM20_17310 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BGM20_17315 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BGM20_17320 ENOG4108MRH transcriptional regulatory protein BGM20_17325 ENOG4107QJT sodium dicarboxylate symporter BGM20_17330 ENOG4106F5Q Membrane BGM20_17340 ENOG4105CJ1 ABC, transporter BGM20_17355 ENOG4105FDT acyl-CoA dehydrogenase BGM20_17375 ENOG4105SZ6 Thioredoxin BGM20_17380 ENOG4105CPF Cell wall formation (By similarity) BGM20_17385 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BGM20_17390 ENOG4105C1J atp-dependent rna helicase BGM20_17395 ENOG410905X membrane-flanked domain protein BGM20_17400 ENOG4105CKV Membrane BGM20_17410 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) BGM20_17415 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BGM20_17420 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BGM20_17430 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BGM20_17435 ENOG4107MMM Anti-sigma-factor antagonist BGM20_17440 ENOG4105FUA antagonist BGM20_17445 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase BGM20_17450 ENOG4107SGM protein serine threonine phosphatase BGM20_17455 ENOG4105WN5 stage II sporulation protein BGM20_17460 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) BGM20_17470 ENOG41064BQ Phosphatase BGM20_17570 ENOG4105VZ8 Transcriptional regulator BGM20_17595 ENOG4108V4B ThiJ pfpI BGM20_17600 ENOG4105VEQ Cold shock protein BGM20_17605 ENOG4108VJ1 Transcriptional regulator (CarD family BGM20_17620 ENOG4108MCI Transcriptional regulator, ARAC family BGM20_17625 ENOG4108UZ3 Transporter BGM20_17630 ENOG41086D8 Transcriptional regulator BGM20_17635 ENOG4107U9B transcriptional regulator BGM20_17640 ENOG4105DXI Major Facilitator superfamily BGM20_17650 ENOG4105CZ9 Domain of unknown function (DU1801) BGM20_17655 ENOG4105GIG BGM20_17680 ENOG4105KRI phosphocarrier protein (HPr BGM20_17685 ENOG4105ST3 Transcriptional regulator BGM20_17690 ENOG4105T38 integral membrane protein BGM20_17695 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGM20_17700 ENOG4108ZMQ domain protein BGM20_17705 ENOG4105MJ9 esterase BGM20_17710 ENOG4107Z6X Transcriptional regulator BGM20_17720 ENOG4105EQ0 Major Facilitator superfamily BGM20_17725 ENOG4108JGH Tetr family transcriptional regulator BGM20_17735 ENOG41082YX Transcriptional regulator, arsr family BGM20_17740 ENOG4107R5R arsenical pump membrane protein BGM20_17750 ENOG4105Z7P Acetyltransferase (GNAT) family BGM20_17755 ENOG4107Y9U Membrane BGM20_17765 ENOG4108SQ9 flavin reductase domain protein, FMN-binding BGM20_17770 ENOG4108ZHR arsR family transcriptional regulator BGM20_17775 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BGM20_17785 ENOG4105ENE Histidine kinase BGM20_17790 ENOG4108VB1 regulatoR BGM20_17795 ENOG4105EYF MMPL domain protein BGM20_17800 ENOG4108WC5 Alpha Beta Hydrolase Fold protein BGM20_17805 ENOG4108UQV Membrane BGM20_17810 ENOG4108Z5V transcriptional regulator, merr family BGM20_17815 ENOG41076HS cation diffusion facilitator family transporter BGM20_17820 ENOG4108TVJ Nitroreductase BGM20_17825 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BGM20_17830 ENOG4108VGI doxx family BGM20_17835 ENOG4105XXY Thioredoxin BGM20_17855 ENOG410900G Protein of unknown function (DUF421) BGM20_17860 ENOG4108QY0 Membrane BGM20_17880 ENOG4105PF9 Transcriptional regulator BGM20_17890 ENOG4105WQG acetyltransferase BGM20_17900 ENOG4105C85 amino acid BGM20_17910 ENOG41062A4 Transcriptional regulator BGM20_17915 ENOG4105EYF MMPL domain protein BGM20_17920 ENOG4108TVJ Nitroreductase BGM20_17925 ENOG4105FS7 Transcriptional regulator BGM20_17930 ENOG4105C2C drug resistance transporter, Bcr CflA BGM20_17940 ENOG4105DRR Transcriptional regulator, GntR family BGM20_17960 ENOG4105G6Z alkaline phosphatase BGM20_17965 ENOG4108ZMX Domain of unknown function (DU1801) BGM20_17975 ENOG4108YM7 Gcn5-related n-acetyltransferase BGM20_17980 ENOG4107TVP HD domain protein BGM20_17985 ENOG41090UD (LipO)protein BGM20_17990 ENOG4105F27 Major Facilitator BGM20_17995 ENOG4105VZJ PTS System BGM20_18000 ENOG4105VCP PTS System BGM20_18005 ENOG4105CK1 PTS System BGM20_18010 ENOG4105CS2 ec 3.2.1.21 BGM20_18015 ENOG4108TZY GntR Family Transcriptional Regulator BGM20_18020 ENOG4105EVU fructokinase BGM20_18025 ENOG4105DG6 mannose-6-phosphate isomerase BGM20_18030 ENOG4105D3P Mannan endo-1,4-beta-mannosidase BGM20_18075 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BGM20_18080 ENOG4105K8N protein family UPF0079, ATPase BGM20_18085 ENOG41072GX Peptidase M22 Glycoprotease BGM20_18090 ENOG410801F ribosomal-protein-alanine acetyltransferase BGM20_18095 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BGM20_18100 ENOG4105C5H ABC transporter BGM20_18105 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BGM20_18110 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) BGM20_18115 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BGM20_18120 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BGM20_18130 ENOG4108TYN CAAX amino terminal protease family protein BGM20_18135 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BGM20_18140 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BGM20_18170 ENOG4105DVF Cytosine-specific methyltransferase BGM20_18175 ENOG4107RHI Cytosine-specific methyltransferase BGM20_18220 ENOG4105PGZ NB-ARC domain BGM20_18225 ENOG4105CPQ Dehydrogenase BGM20_18230 ENOG4105CT4 transporter BGM20_18240 ENOG41087YS Phage shock protein A BGM20_18245 ENOG4105DQX Zinc finger domain BGM20_18250 ENOG4108WV1 Pfam:DUF477 BGM20_18260 ENOG4108ZMR Ion transport 2 domain-containing protein BGM20_18265 ENOG4107QNK )-transporter BGM20_18295 ENOG4107YUH hydrolase BGM20_18305 ENOG4107STQ Multicopper oxidase BGM20_18310 ENOG4105C85 amino acid BGM20_18325 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BGM20_18345 ENOG4105C7N Xanthine uracil vitamin C permease BGM20_18370 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BGM20_18375 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BGM20_18380 ENOG4105C83 adenylosuccinate lyase BGM20_18385 ENOG4105C8V SAICAR synthetase BGM20_18390 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BGM20_18395 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I BGM20_18400 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii BGM20_18410 ENOG4105CXB phosphoribosylaminoimidazole synthetase BGM20_18415 ENOG4108V3E phosphoribosylglycinamide formyltransferase BGM20_18420 ENOG4105DC1 bifunctional purine biosynthesis protein purh BGM20_18425 ENOG4105C12 Phosphoribosylglycinamide synthetase BGM20_18435 ENOG4105DVH amino acid BGM20_18450 ENOG4108R5T secreted protein BGM20_18455 ENOG4105KGF protein, YerC YecD BGM20_18460 ENOG4105CBC glutamate synthase BGM20_18465 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) BGM20_18470 ENOG4105C4R Atp-dependent dna helicase BGM20_18475 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BGM20_18485 ENOG4105CRN Aminoglycoside phosphotransferase BGM20_18490 ENOG4105KT7 mgtC SapB transporter BGM20_18495 ENOG4105CK7 Sodium proline symporter BGM20_18500 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BGM20_18505 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BGM20_18510 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BGM20_18515 ENOG4108IG5 Transcriptional regulator BGM20_18525 ENOG4105CBD Diacylglycerol kinase BGM20_18530 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BGM20_18565 ENOG4108HFV BGM20_18585 ENOG4105CDY transcriptional regulatory protein BGM20_18595 ENOG4105M4P Tetr family transcriptional regulator BGM20_18600 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein BGM20_18605 ENOG4107S9F NmrA family BGM20_18620 ENOG4105WEF catalase BGM20_18625 ENOG4105M18 -acetyltransferase BGM20_18640 ENOG4105C2F Histidine kinase BGM20_18645 ENOG4105EQD regulatoR BGM20_18650 ENOG410769Z extracellular solute-binding protein family 1 BGM20_18655 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BGM20_18660 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BGM20_18665 ENOG4105F5H Glycosyl Hydrolase Family 88 BGM20_18670 ENOG41075H3 AraC family transcriptional regulator BGM20_18675 ENOG4107TDE lipolytic protein G-D-S-L family BGM20_18695 ENOG4105CX8 fg-gap repeat protein BGM20_18700 ENOG4107TDE lipolytic protein G-D-S-L family BGM20_18710 ENOG4105EKC BGM20_18715 ENOG4105E0S extracellular solute-binding protein family 1 BGM20_18725 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component BGM20_18730 ENOG4105F8D glycoside hydrolase family 4 BGM20_18735 ENOG4105H67 Protein of unknown function (DUF421) BGM20_18740 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BGM20_18745 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BGM20_18765 ENOG4106I4J membrane BGM20_18770 ENOG4108PCN EamA-like transporter family BGM20_18775 ENOG41082F9 transcriptional regulator BGM20_18780 ENOG41061H0 Monooxygenase BGM20_18790 ENOG4108R1P BGM20_18795 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BGM20_18800 ENOG4105E0M Sulfatase BGM20_18805 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BGM20_18815 ENOG41090R9 glycosyltransferase BGM20_18820 ENOG4107R51 Glycosyl transferase, family 2 BGM20_18825 ENOG41090R9 glycosyltransferase BGM20_18830 ENOG4105EU0 Major facilitator Superfamily BGM20_18840 ENOG4105CUB amino acid BGM20_18845 ENOG4105C26 Dehydrogenase BGM20_18850 ENOG4105FKZ Methyl-accepting chemotaxis BGM20_18855 ENOG4105C5H ABC transporter BGM20_18865 ENOG4107SWG transcriptional regulator MERR family BGM20_18870 ENOG4105DXB Major Facilitator superfamily BGM20_18890 ENOG4105C5H ABC transporter BGM20_18895 ENOG4105FDU atp-dependent rna helicase BGM20_18905 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BGM20_18925 ENOG4105E6M Sulphatase-modifying factor protein BGM20_18930 ENOG4105E0A ABC, transporter BGM20_18935 ENOG4108U1V ABC transporter, permease BGM20_18940 ENOG4105DQ5 transport system permease protein BGM20_18945 ENOG4108HUF Transporter BGM20_18960 ENOG4108J20 pectate lyase BGM20_18965 ENOG4107QPK )-transporter BGM20_18975 ENOG4108MRH transcriptional regulatory protein BGM20_19005 ENOG410855V Acylphosphatase BGM20_19010 ENOG4108RPX mosc domain containing protein BGM20_19030 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BGM20_19055 ENOG4105GEU Spore germination protein BGM20_19065 ENOG4108Q5U germination protein, ger(x)c family BGM20_19075 ENOG4105C5Y PTS System BGM20_19080 ENOG4105CG3 alpha amylase, catalytic region BGM20_19085 ENOG4107414 GntR family transcriptional regulator BGM20_19090 ENOG4108RCM Nitroreductase BGM20_19095 ENOG4105CGH 5'-nucleotidase BGM20_19100 ENOG4107RKG DJ-1/PfpI family BGM20_19115 ENOG4105KJF protein tyrosine phosphatase BGM20_19125 ENOG4107U9T Pfam:Ribonuclease_BN BGM20_19135 ENOG4108ISG Major Facilitator BGM20_19145 ENOG4105UPD Calcium Proton BGM20_19155 ENOG4105D8X mechanosensitive ion channel BGM20_19175 ENOG4106KE4 Dehydrogenase BGM20_19180 ENOG4105D7N magnesium and cobalt transport protein CorA BGM20_19190 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BGM20_19210 ENOG4107RUY (E1 component), alpha subunit BGM20_19220 ENOG4107QKR Dehydrogenase BGM20_19230 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BGM20_19235 ENOG41069DP small acid-soluble spore protein BGM20_19240 ENOG4105KK4 UPF0060 membrane protein BGM20_19270 ENOG4105F8D glycoside hydrolase family 4 BGM20_19275 ENOG4108Q3X Transcriptional regulator BGM20_19280 ENOG4105CI1 PTS System BGM20_19285 ENOG4105BZ1 (ABC) transporter BGM20_19290 ENOG4105BZ1 (ABC) transporter BGM20_19300 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BGM20_19305 ENOG4105ID8 Transcriptional regulator, ARAC family BGM20_19310 ENOG4107QNK )-transporter BGM20_19315 ENOG4107QP6 Xylose isomerase domain protein TIM barrel BGM20_19320 ENOG4105CIB oxidoreductase Domain protein BGM20_19325 ENOG4105BZU Histidine kinase BGM20_19330 ENOG4105WH1 Two component transcriptional regulator luxr family BGM20_19335 ENOG4105CJ1 ABC, transporter BGM20_19340 ENOG41090VJ ABC-2 type transporter BGM20_19345 ENOG4108KYE ABC-2 type transporter BGM20_19350 ENOG4105U3E Transcriptional regulator BGM20_19355 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold BGM20_19365 ENOG4108YYS metal-dependent hydrolase (By similarity) BGM20_19370 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGM20_19375 ENOG410834F Transcriptional regulator BGM20_19385 ENOG4108MES Periplasmic binding protein BGM20_19390 ENOG4105DQ5 transport system permease protein BGM20_19395 ENOG4108IHU transport system permease protein BGM20_19400 ENOG4105JAB phenazine biosynthesis protein, phzf family BGM20_19405 ENOG4107Y03 Nitroreductase BGM20_19420 ENOG4105ECP epimerase BGM20_19440 ENOG4105F27 Major Facilitator BGM20_19460 ENOG4106AKJ BGM20_19465 ENOG4105D74 hydrolase BGM20_19470 ENOG4105CKK Glycosyl transferase, family 2 BGM20_19475 ENOG4105EJV Membrane BGM20_19480 ENOG41067AE Membrane-bound metal-dependent hydrolase BGM20_19485 ENOG4105CEN a g-specific adenine glycosylase BGM20_19490 ENOG4106BXE BGM20_19495 ENOG4105CAN Short-chain dehydrogenase reductase Sdr BGM20_19510 ENOG4105EVI UPF0374 protein BGM20_19515 ENOG4105BZ1 (ABC) transporter BGM20_19520 ENOG4107NBY Membrane BGM20_19530 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BGM20_19535 ENOG4105G5W regulator Fur family BGM20_19650 ENOG4108N23 SpoOM-related protein BGM20_19665 ENOG4105EC3 peptidase S51, dipeptidase E BGM20_19670 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BGM20_19675 ENOG4105DNP FAD linked oxidase domain protein BGM20_19690 ENOG4105E2Y ABC, transporter BGM20_19695 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BGM20_19700 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BGM20_19715 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BGM20_19720 ENOG4107D63 BGM20_19725 ENOG4105VZ8 Transcriptional regulator BGM20_19740 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BGM20_19750 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BGM20_19770 ENOG4105CYN Serine protein kinase BGM20_19775 ENOG4106AKX UPF0229 protein BGM20_19785 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BGM20_19790 ENOG4105CW7 secretion protein, HlyD family BGM20_19795 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGM20_19800 ENOG4105CS1 NAD(P)H quinone oxidoreductase BGM20_19815 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BGM20_19820 ENOG4105CZV ABC transporter BGM20_19825 ENOG4105CJ1 ABC, transporter BGM20_19830 ENOG4108TU7 Inherit from COG: (ABC) transporter BGM20_19835 ENOG4105VEQ Cold shock protein BGM20_19845 ENOG4105BZU Histidine kinase BGM20_19885 ENOG4108YBP pseudouridine synthase BGM20_19895 ENOG41080XP Cbs domain BGM20_19900 ENOG4107YBY Hydrolase BGM20_19905 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BGM20_19910 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BGM20_19915 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BGM20_19925 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BGM20_19930 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BGM20_19940 ENOG4105BZU Histidine kinase BGM20_19945 ENOG4105WH1 Two component transcriptional regulator luxr family BGM20_19980 ENOG4105ED1 spovr family BGM20_19985 ENOG4105G6Z alkaline phosphatase BGM20_20000 ENOG4105BZN citrate synthase BGM20_20010 ENOG4105CUB amino acid BGM20_20015 ENOG4105C8J )-transporter BGM20_20020 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGM20_20035 ENOG4105J37 BGM20_20040 ENOG4108AEY RNA polymerase sigma factor BGM20_20045 ENOG4108FN7 Aldo keto reductase BGM20_20050 ENOG4105F6E Acyl-transferase BGM20_20055 ENOG4105C37 (CBS) domain BGM20_20065 ENOG4105CHM Aminotransferase BGM20_20070 ENOG4105C37 (CBS) domain BGM20_20080 ENOG4105WMR Protein CrcB homolog BGM20_20085 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BGM20_20095 ENOG4105D64 Mechanosensitive ion channel BGM20_20100 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BGM20_20105 ENOG4107VMI polysaccharide deacetylase BGM20_20110 ENOG4105F0I Aminotransferase BGM20_20130 ENOG4105BZ1 (ABC) transporter BGM20_20135 ENOG4105BZ1 (ABC) transporter BGM20_20155 ENOG410839P BGM20_20165 ENOG4106MP8 UPF0754 membrane protein BGM20_20170 ENOG4105WZB UPF0342 protein BGM20_20175 ENOG4105F1N DNA alkylation repair BGM20_20185 ENOG4105D4P Coproporphyrinogen iii oxidase BGM20_20190 ENOG4107S91 Sodium hydrogen exchanger BGM20_20195 ENOG4105NCW Trka-c domain protein BGM20_20205 ENOG4105CGU Enoyl-CoA hydratase BGM20_20215 ENOG4108IUX (ABC) transporter BGM20_20220 ENOG4105RHA ABC transporter, permease BGM20_20225 ENOG4107VRP DNA repair exonuclease BGM20_20230 ENOG4106D4I domain protein BGM20_20235 ENOG4105EQI Metal Dependent Phosphohydrolase BGM20_20245 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BGM20_20280 ENOG4105NBU tryptophan transport protein BGM20_20285 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BGM20_20290 ENOG4105K59 histidine triad (HIT) protein BGM20_20325 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BGM20_20330 ENOG4105BZ4 penicillin-binding protein BGM20_20335 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BGM20_20340 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BGM20_20345 ENOG4105C1Q protoporphyrinogen oxidase BGM20_20355 ENOG4105ECB domain protein BGM20_20365 ENOG41090T1 Membrane BGM20_20375 ENOG4105DER m42 family BGM20_20390 ENOG4106AXD BGM20_20395 ENOG4108RQ5 Beta-lactamase domain-containing protein BGM20_20400 ENOG4105DF9 Lipoate-protein, ligase BGM20_20410 ENOG4105CEY Amp-dependent synthetase and ligase BGM20_20420 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BGM20_20425 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BGM20_20430 ENOG4105KD7 acetyltransferase BGM20_20440 ENOG4108HUF Transporter BGM20_20445 ENOG4107TB6 phosphoglycerate mutase BGM20_20455 ENOG4107F3J Amp-dependent synthetase and ligase BGM20_20460 ENOG4107ZYJ bioY protein BGM20_20465 ENOG4106YBV Methyl-accepting chemotaxis BGM20_20485 ENOG4105XVF Competence transcription factor BGM20_20490 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BGM20_20495 ENOG4105X3H Excalibur domain protein BGM20_20500 ENOG4105E1V na solute symporter BGM20_20505 ENOG4106CAD Protein of unknown function (DUF3311) BGM20_20510 ENOG41060YP BGM20_20525 ENOG4107SCK Monooxygenase BGM20_20530 ENOG4108INS Transcriptional regulator BGM20_20545 ENOG4105TRI Hydrolase BGM20_20560 ENOG4108KK1 membrane protein AbrB duplication BGM20_20565 ENOG4106K7D Major facilitator family transporter BGM20_20575 ENOG4105VWP Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding BGM20_20590 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BGM20_20600 ENOG4105EYH Exonuclease BGM20_20655 ENOG4105ERH Fumarylacetoacetate hydrolase BGM20_20665 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BGM20_20675 ENOG4105CAQ asparagine synthetase BGM20_20690 ENOG4105UQX Mate efflux family protein BGM20_20695 ENOG4106HBX Transcriptional Regulator AraC Family BGM20_20700 ENOG4105ETE Transcriptional regulator (LacI family BGM20_20705 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BGM20_20710 ENOG4105SF0 DinB family BGM20_20715 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BGM20_20720 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGM20_20725 ENOG4105MYW Pentapeptide repeat protein BGM20_20730 ENOG4107S9D Alpha beta hydrolase BGM20_20735 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BGM20_20740 ENOG4107RIQ Sulfate adenylate transferase BGM20_20750 ENOG4108N5B 2-phosphosulfolactate phosphatase BGM20_20755 ENOG41061P3 phosphosulfolactate synthase BGM20_20765 ENOG4105DIA mandelate racemase muconate lactonizing BGM20_20770 ENOG4107RCC Major Facilitator Superfamily BGM20_20775 ENOG4108SZE gCN5-related N-acetyltransferase BGM20_20780 ENOG4105MA6 gCN5-related N-acetyltransferase BGM20_20790 ENOG4108VPT UPF0234 protein BGM20_20795 ENOG4105QNR S1 RNA binding domain protein BGM20_20815 ENOG4105K7K Transcriptional regulator BGM20_20825 ENOG410751J BGM20_20830 ENOG4105D4Y metalloprotease BGM20_20835 ENOG4105EPR degv family BGM20_20840 ENOG4107AYK membrAne BGM20_20850 ENOG41073B9 BGM20_20860 ENOG4108KP7 hydrolase BGM20_20865 ENOG4108MXZ Esterase BGM20_20870 ENOG4105VG1 fes assembly suf system protein BGM20_20880 ENOG4105IQ5 FAD linked oxidase domain protein BGM20_20890 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BGM20_20905 ENOG4105C8Y Acetylornithine aminotransferase BGM20_20910 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BGM20_20920 ENOG4105DBV ornithine carbamoyltransferase BGM20_20945 ENOG4107RMD Basic membrane lipoprotein BGM20_20960 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BGM20_20965 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BGM20_20975 ENOG4105C3U ABC transporter BGM20_20980 ENOG4108JQ7 (ABC) transporter BGM20_20995 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGM20_21005 ENOG4105C31 Tryptophanyl-tRNA synthetase BGM20_21010 ENOG4108J59 Extracellular solute-binding protein, family 5 BGM20_21015 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BGM20_21020 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGM20_21030 ENOG4108JQ7 (ABC) transporter BGM20_21045 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) BGM20_21050 ENOG4108ZCF integral membrane protein BGM20_21055 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis BGM20_21065 ENOG4105DPN Oligoendopeptidase f BGM20_21080 ENOG4105T58 Dithiol-disulfide isomerase BGM20_21085 ENOG4108Z18 K06886 hemoglobin BGM20_21090 ENOG4105E4C Lytic transglycosylase catalytic BGM20_21095 ENOG4105MIX Adenylate cyclase BGM20_21110 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BGM20_21115 ENOG4105EMS pseudouridine synthase BGM20_21130 ENOG4105ETU transcriptional activator (TenA BGM20_21135 ENOG4108VEU Thiamine monophosphate synthase BGM20_21150 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) BGM20_21155 ENOG4105D06 uba thif-type nad fad binding protein