locus-tag	class	description
MW696_00015	COG1392	Phosphate transport regulator
MW696_00020	COG0405	Gamma-glutamyltransferase
MW696_00025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MW696_00035	COG4208	sulfate ABC transporter
MW696_00045	COG5578	integral membrane protein
MW696_00050	COG2972	Histidine kinase
MW696_00055	COG2207	Transcriptional regulator
MW696_00055	COG4753	response regulator
MW696_00060	COG1653	transport
MW696_00065	COG1175	transmembrane transport
MW696_00070	COG0395	ABC-type sugar transport system, permease component
MW696_00075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MW696_00080	COG2207	Transcriptional regulator
MW696_00085	COG2755	lipolytic protein G-D-S-L family
MW696_00095	COG5578	integral membrane protein
MW696_00100	COG3401	FG-GAP repeat protein
MW696_00105	COG3401	FG-GAP repeat protein
MW696_00110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_00120	COG2755	lipolytic protein G-D-S-L family
MW696_00125	COG1874	Beta-galactosidase
MW696_00135	COG1653	transport
MW696_00140	COG4209	transmembrane transport
MW696_00145	COG0395	ABC-type sugar transport system, permease component
MW696_00150	COG0531	amino acid
MW696_00155	COG0346	lactoylglutathione lyase activity
MW696_00160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MW696_00165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MW696_00170	COG2362	D-Aminopeptidase
MW696_00175	COG0601	transmembrane transport
MW696_00180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MW696_00185	COG0444	Belongs to the ABC transporter superfamily
MW696_00190	COG4166	transmembrane transport
MW696_00195	COG1619	proteins homologs of microcin C7 resistance protein MccF
MW696_00200	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_00205	COG0791	NLP P60 protein
MW696_00210	COG4608	Belongs to the ABC transporter superfamily
MW696_00225	COG1834	amidinotransferase
MW696_00230	COG1607	acyl-coa hydrolase
MW696_00235	COG3866	Pectate lyase
MW696_00240	COG2318	DinB family
MW696_00245	COG2076	Multidrug Resistance protein
MW696_00250	COG2076	Multidrug Resistance protein
MW696_00255	COG0788	formyltetrahydrofolate deformylase activity
MW696_00260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MW696_00265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MW696_00270	COG1764	response to oxidative stress
MW696_00275	COG1846	Transcriptional regulator
MW696_00280	COG1764	response to oxidative stress
MW696_00290	COG0590	tRNA wobble adenosine to inosine editing
MW696_00310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MW696_00315	COG1404	Belongs to the peptidase S8 family
MW696_00325	COG2239	Acts as a magnesium transporter
MW696_00335	COG0789	Transcriptional regulator
MW696_00350	COG1846	Transcriptional regulator
MW696_00355	COG1793	dna ligase
MW696_00355	COG3285	dna ligase
MW696_00360	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MW696_00365	COG3300	MHYT domain
MW696_00365	COG5001	Diguanylate cyclase
MW696_00370	COG0586	Pfam SNARE associated Golgi protein
MW696_00375	COG0861	Integral membrane protein TerC family
MW696_00380	COG1191	sigma factor activity
MW696_00400	COG0501	Belongs to the peptidase M48B family
MW696_00405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MW696_00410	COG0768	penicillin binding
MW696_00425	COG3594	Acyltransferase
MW696_00430	COG5002	protein histidine kinase activity
MW696_00435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MW696_00445	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MW696_00450	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MW696_00455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MW696_00460	COG0436	Aminotransferase
MW696_00465	COG1850	ribulose-bisphosphate carboxylase activity
MW696_00470	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MW696_00470	COG0235	Class ii aldolase
MW696_00475	COG0235	Class ii aldolase
MW696_00475	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MW696_00480	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MW696_00485	COG0346	lactoylglutathione lyase activity
MW696_00490	COG3339	Conserved Protein
MW696_00500	COG3852	Histidine kinase
MW696_00505	COG1846	Transcriptional regulator
MW696_00510	COG1360	Flagellar Motor Protein
MW696_00515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MW696_00520	COG0542	response to heat
MW696_00525	COG3949	Membrane
MW696_00530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MW696_00535	COG0720	synthase
MW696_00540	COG0602	queuosine metabolic process
MW696_00545	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MW696_00560	COG0456	acetyltransferase
MW696_00580	COG4873	Protein conserved in bacteria
MW696_00590	COG3773	Cell wall hydrolase
MW696_00595	COG2244	polysaccharide biosynthetic process
MW696_00600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_00605	COG2217	Heavy metal translocating P-type atpase
MW696_00610	COG0006	proline dipeptidase activity
MW696_00615	COG1609	Transcriptional regulator
MW696_00620	COG3711	transcriptional antiterminator
MW696_00625	COG1263	PTS System
MW696_00625	COG2190	(PTS) system
MW696_00625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_00630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_00635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MW696_00645	COG1533	DNA photolyase activity
MW696_00650	COG0456	acetyltransferase
MW696_00655	COG0840	transmembrane signaling receptor activity
MW696_00660	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_00665	COG2084	Dehydrogenase
MW696_00670	COG2340	Cysteine-rich secretory protein family
MW696_00675	COG0768	penicillin binding
MW696_00680	COG4191	Histidine kinase
MW696_00685	COG0436	Aminotransferase
MW696_00705	COG0784	Response regulator, receiver
MW696_00705	COG0835	chemotaxis
MW696_00715	COG2814	Major facilitator Superfamily
MW696_00720	COG1376	ErfK ybiS ycfS ynhG family protein
MW696_00725	COG1408	metallophosphoesterase
MW696_00730	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_00735	COG2200	EAL domain
MW696_00740	COG4703	Protein of unknown function (DUF1797)
MW696_00750	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MW696_00760	COG0517	IMP dehydrogenase activity
MW696_00765	COG0583	DNA-binding transcription factor activity
MW696_00770	COG0716	FMN binding
MW696_00780	COG0716	FMN binding
MW696_00785	COG2171	N-acyltransferase activity
MW696_00790	COG1473	amidohydrolase
MW696_00800	COG0450	alkyl hydroperoxide reductase
MW696_00805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_00820	COG0746	molybdenum cofactor guanylyltransferase activity
MW696_00825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MW696_00830	COG0303	'Molybdopterin
MW696_00835	COG1763	Mo-molybdopterin cofactor biosynthetic process
MW696_00840	COG0314	molybdopterin synthase activity
MW696_00845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MW696_00855	COG1132	(ABC) transporter
MW696_00860	COG1132	(ABC) transporter
MW696_00870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MW696_00875	COG1136	(ABC) transporter
MW696_00880	COG0577	efflux transmembrane transporter activity
MW696_00890	COG1349	DNA-binding transcription factor activity
MW696_00895	COG1105	Belongs to the carbohydrate kinase PfkB family
MW696_00900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_00900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_00900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_00920	COG0488	(ABC) transporter
MW696_00925	COG2309	aminopeptidase activity
MW696_00935	COG1077	Cell shape determining protein MreB Mrl
MW696_00940	COG2002	toxin-antitoxin pair type II binding
MW696_00945	COG3852	Histidine kinase
MW696_00950	COG0569	domain protein
MW696_00955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MW696_00960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MW696_00965	COG5503	Protein of unknown function (DUF1447)
MW696_00970	COG0561	phosphatase activity
MW696_00975	COG0242	peptide deformylase activity
MW696_00985	COG0497	DNA recombination
MW696_00990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MW696_00995	COG0022	dehydrogenase e1 component
MW696_01000	COG0508	dehydrogenase complex catalyzes the overall conversion of
MW696_01005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MW696_01010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_01020	COG1982	Orn Lys Arg decarboxylase major
MW696_01025	COG4476	Belongs to the UPF0223 family
MW696_01030	COG4493	Belongs to the UPF0637 family
MW696_01040	COG0483	inositol monophosphate 1-phosphatase activity
MW696_01060	COG1217	gtp-binding protein TYPA
MW696_01070	COG1846	Transcriptional regulator
MW696_01075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MW696_01080	COG4896	Protein conserved in bacteria
MW696_01090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MW696_01095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MW696_01100	COG2066	Belongs to the glutaminase family
MW696_01105	COG4838	Belongs to the UPF0358 family
MW696_01110	COG0772	Belongs to the SEDS family
MW696_01115	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MW696_01120	COG1612	heme a metabolic process
MW696_01125	COG0109	protoheme IX farnesyltransferase activity
MW696_01130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MW696_01130	COG2010	Cytochrome c
MW696_01135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MW696_01140	COG1845	cytochrome c oxidase, subunit III
MW696_01145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MW696_01150	COG3336	cytochrome c oxidase
MW696_01160	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MW696_01165	COG2340	Cysteine-rich secretory protein family
MW696_01190	COG3679	Belongs to the UPF0342 family
MW696_01195	COG4471	UPF0298 protein
MW696_01200	COG0742	ribosomal rna small subunit methyltransferase
MW696_01205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MW696_01210	COG3314	Sporulation integral membrane protein YlbJ
MW696_01215	COG3480	Lon protease (S16) C-terminal proteolytic domain
MW696_01220	COG1323	Belongs to the UPF0348 family
MW696_01225	COG1399	metal-binding, possibly nucleic acid-binding protein
MW696_01230	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MW696_01240	COG0454	-acetyltransferase
MW696_01245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MW696_01250	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MW696_01255	COG2001	Belongs to the MraZ family
MW696_01260	COG0275	rRNA processing
MW696_01265	COG4839	cell division protein FtsL
MW696_01270	COG0768	penicillin binding
MW696_01275	COG0768	penicillin binding
MW696_01280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MW696_01285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MW696_01290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MW696_01295	COG0772	Belongs to the SEDS family
MW696_01300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MW696_01305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MW696_01310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MW696_01315	COG3879	Bacterial protein of unknown function (DUF881)
MW696_01320	COG3879	Bacterial protein of unknown function (DUF881)
MW696_01325	COG3856	small basic protein
MW696_01330	COG0849	cell division
MW696_01335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MW696_01345	COG1404	Belongs to the peptidase S8 family
MW696_01345	COG4412	M6 family metalloprotease domain protein
MW696_01355	COG1191	sigma factor activity
MW696_01360	COG1191	sigma factor activity
MW696_01365	COG1119	ATPase activity
MW696_01370	COG0500	methyltransferase
MW696_01375	COG1873	PFAM PRC-barrel domain
MW696_01380	COG1496	oxidoreductase activity
MW696_01385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MW696_01390	COG1799	cell septum assembly
MW696_01395	COG0762	integral membrane protein
MW696_01400	COG2302	S4 RNA-binding domain
MW696_01405	COG3599	regulation of cell shape
MW696_01410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MW696_01415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MW696_01420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MW696_01425	COG0564	pseudouridine synthase activity
MW696_01430	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MW696_01435	COG2233	PERMEase
MW696_01440	COG0540	Belongs to the ATCase OTCase family
MW696_01445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MW696_01450	COG0505	Belongs to the CarA family
MW696_01455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MW696_01460	COG0543	2 iron, 2 sulfur cluster binding
MW696_01465	COG0167	dihydroorotate dehydrogenase activity
MW696_01470	COG0284	orotidine-5'-phosphate decarboxylase activity
MW696_01475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MW696_01490	COG0175	sulfate reduction
MW696_01495	COG0306	phosphate transporter
MW696_01500	COG2046	Belongs to the sulfate adenylyltransferase family
MW696_01505	COG0529	Catalyzes the synthesis of activated sulfate
MW696_01510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MW696_01515	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
MW696_01520	COG1648	precorrin-2 dehydrogenase activity
MW696_01530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MW696_01535	COG1561	YicC-like family, N-terminal region
MW696_01540	COG2052	Domain of unknown function (DUF370)
MW696_01545	COG0194	GDP metabolic process
MW696_01550	COG1758	RNA polymerase activity
MW696_01555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MW696_01560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MW696_01565	COG0242	peptide deformylase activity
MW696_01570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MW696_01575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MW696_01575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MW696_01580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MW696_01585	COG0631	protein serine/threonine phosphatase activity
MW696_01590	COG0515	serine threonine protein kinase
MW696_01590	COG2815	serine threonine protein kinase
MW696_01595	COG1162	GTPase activity
MW696_01600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MW696_01605	COG1564	THIamine pyrophosphokinase
MW696_01615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MW696_01620	COG1302	Protein conserved in bacteria
MW696_01625	COG1461	Dihydroxyacetone kinase
MW696_01630	COG1760	l-serine dehydratase
MW696_01635	COG1760	l-serine dehydratase
MW696_01640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MW696_01645	COG1349	DNA-binding transcription factor activity
MW696_01650	COG0416	fatty acid biosynthetic process
MW696_01655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MW696_01660	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_01665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MW696_01670	COG0571	ribonuclease III activity
MW696_01675	COG1196	nuclear chromosome segregation
MW696_01680	COG0552	protein localization to endoplasmic reticulum
MW696_01685	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MW696_01690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MW696_01695	COG0228	four-way junction DNA binding
MW696_01700	COG1837	Belongs to the UPF0109 family
MW696_01710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MW696_01715	COG0336	Belongs to the RNA methyltransferase TrmD family
MW696_01720	COG0335	large ribosomal subunit rRNA binding
MW696_01725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MW696_01730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MW696_01740	COG2257	FlhB HrpN YscU SpaS Family
MW696_01745	COG0045	succinate-CoA ligase (ADP-forming) activity
MW696_01750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MW696_01755	COG0758	DNA mediated transformation
MW696_01760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MW696_01765	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MW696_01770	COG4974	Belongs to the 'phage' integrase family
MW696_01775	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MW696_01780	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MW696_01785	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MW696_01790	COG1815	bacterial-type flagellum-dependent cell motility
MW696_01795	COG1558	bacterial-type flagellum-dependent cell motility
MW696_01800	COG1677	Flagellar hook-basal body complex protein FliE
MW696_01805	COG1766	The M ring may be actively involved in energy transduction
MW696_01810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MW696_01815	COG1317	bacterial-type flagellum organization
MW696_01820	COG1157	protein secretion by the type III secretion system
MW696_01825	COG2882	bacterial-type flagellum organization
MW696_01835	COG3144	bacterial-type flagellum assembly
MW696_01840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MW696_01845	COG4786	Flagellar basal body rod
MW696_01850	COG1582	Flagellar protein (FlbD)
MW696_01855	COG1580	Controls the rotational direction of flagella during chemotaxis
MW696_01860	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MW696_01865	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MW696_01865	COG1776	CheC inhibitor of MCP methylation
MW696_01870	COG2201	protein-glutamate methylesterase activity
MW696_01875	COG3190	flagellar
MW696_01880	COG1338	Plays a role in the flagellum-specific transport system
MW696_01885	COG1987	bacterial-type flagellum assembly
MW696_01890	COG1684	flagellar biosynthetic protein fliR
MW696_01895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MW696_01900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MW696_01905	COG1419	protein localization to endoplasmic reticulum
MW696_01910	COG0455	bacterial-type flagellum organization
MW696_01915	COG2201	protein-glutamate methylesterase activity
MW696_01920	COG0643	Histidine kinase
MW696_01920	COG2198	Histidine kinase
MW696_01925	COG0835	chemotaxis
MW696_01930	COG1776	CheC inhibitor of MCP methylation
MW696_01935	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MW696_01940	COG1191	sigma factor activity
MW696_01950	COG0052	Belongs to the universal ribosomal protein uS2 family
MW696_01955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MW696_01960	COG0528	UMP kinase activity
MW696_01965	COG0233	cytoplasmic translational termination
MW696_01970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MW696_01975	COG4589	Belongs to the CDS family
MW696_01980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MW696_01985	COG0750	zinc metalloprotease
MW696_01990	COG0442	prolyl-tRNA aminoacylation
MW696_01995	COG2176	DNA-directed DNA polymerase activity
MW696_02005	COG0457	Tetratricopeptide repeat
MW696_02010	COG0779	Required for maturation of 30S ribosomal subunits
MW696_02015	COG0195	Participates in both transcription termination and antitermination
MW696_02020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MW696_02025	COG1358	cellular component organization or biogenesis
MW696_02030	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MW696_02035	COG1550	Protein conserved in bacteria
MW696_02040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MW696_02045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MW696_02050	COG0196	riboflavin kinase activity
MW696_02055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MW696_02060	COG1185	polyribonucleotide nucleotidyltransferase activity
MW696_02065	COG0726	polysaccharide deacetylase
MW696_02070	COG0612	Peptidase, M16
MW696_02075	COG1873	PFAM PRC-barrel domain
MW696_02080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MW696_02085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MW696_02090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MW696_02095	COG0527	aspartate kinase activity
MW696_02105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MW696_02110	COG0740	serine-type endopeptidase activity
MW696_02120	COG4980	gas vesicle protein
MW696_02120	COG1674	ftsk spoiiie
MW696_02125	COG2188	Transcriptional regulator
MW696_02130	COG2814	Major facilitator Superfamily
MW696_02135	COG0612	Peptidase, M16
MW696_02140	COG0612	Peptidase, M16
MW696_02145	COG0300	oxidoreductase activity
MW696_02160	COG1426	Protein conserved in bacteria
MW696_02165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MW696_02170	COG1058	Belongs to the CinA family
MW696_02170	COG1546	Belongs to the CinA family
MW696_02180	COG1418	mRNA catabolic process
MW696_02185	COG1692	metallophosphoesterase
MW696_02190	COG2359	stage V sporulation protein S
MW696_02200	COG1063	alcohol dehydrogenase
MW696_02205	COG0156	8-amino-7-oxononanoate synthase activity
MW696_02210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MW696_02215	COG4550	Control of competence regulator ComK, YlbF/YmcA
MW696_02225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MW696_02230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MW696_02235	COG2273	Hydrolase Family 16
MW696_02245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_02290	COG4282	regulation of fungal-type cell wall biogenesis
MW696_02315	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MW696_02340	COG3866	Pectate lyase
MW696_02345	COG3507	Belongs to the glycosyl hydrolase 43 family
MW696_02350	COG1522	sequence-specific DNA binding
MW696_02355	COG1902	pentaerythritol trinitrate reductase activity
MW696_02360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MW696_02385	COG0402	S-adenosylhomocysteine deaminase activity
MW696_02415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MW696_02425	COG2323	membrane
MW696_02430	COG3619	membrane
MW696_02440	COG2814	Major facilitator Superfamily
MW696_02445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_02450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_02455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_02460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_02465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_02470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_02475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_02475	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MW696_02480	COG0393	Putative heavy-metal-binding
MW696_02485	COG0398	Pfam SNARE associated Golgi protein
MW696_02490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MW696_02495	COG1819	glycosyl
MW696_02500	COG0531	amino acid
MW696_02505	COG5577	PFAM Coat F domain
MW696_02515	COG3858	chitin binding
MW696_02515	COG1388	LysM domain
MW696_02520	COG1309	transcriptional regulator
MW696_02530	COG1764	response to oxidative stress
MW696_02535	COG2076	Multidrug Resistance protein
MW696_02540	COG2076	Multidrug Resistance protein
MW696_02555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MW696_02560	COG1923	regulation of RNA biosynthetic process
MW696_02570	COG1780	Probably involved in ribonucleotide reductase function
MW696_02575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MW696_02580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MW696_02585	COG4112	unkown
MW696_02590	COG1802	Transcriptional regulator
MW696_02595	COG0697	spore germination
MW696_02625	COG4282	regulation of fungal-type cell wall biogenesis
MW696_02630	COG1073	alpha beta
MW696_02640	COG0464	growth
MW696_02645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MW696_02650	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MW696_02655	COG0789	Transcriptional regulator
MW696_02660	COG0174	glutamine synthetase
MW696_02680	COG3655	Transcriptional regulator
MW696_02685	COG5444	nuclease activity
MW696_02695	COG0457	Tetratricopeptide repeat
MW696_02710	COG2814	Major facilitator Superfamily
MW696_02715	COG0457	Tetratricopeptide repeat
MW696_02720	COG0457	Tetratricopeptide repeat
MW696_02730	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MW696_02760	COG2814	Major facilitator Superfamily
MW696_02765	COG0457	Tetratricopeptide repeat
MW696_02770	COG0490	domain, Protein
MW696_02775	COG0475	glutathione-regulated potassium exporter activity
MW696_02795	COG0756	dUTP diphosphatase activity
MW696_02805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MW696_02830	COG1231	oxidoreductase activity
MW696_02835	COG1309	transcriptional regulator
MW696_02840	COG2076	Multidrug Resistance protein
MW696_02845	COG2076	Multidrug Resistance protein
MW696_02850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_02925	COG5434	Belongs to the glycosyl hydrolase 28 family
MW696_02930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MW696_02935	COG1388	LysM domain
MW696_02940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MW696_02945	COG4224	UPF0291 protein
MW696_02950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MW696_02960	COG3763	UPF0154 protein
MW696_02970	COG0785	Cytochrome C biogenesis protein
MW696_02975	COG2201	protein-glutamate methylesterase activity
MW696_02980	COG4846	Membrane protein involved in cytochrome C biogenesis
MW696_02990	COG0071	Belongs to the small heat shock protein (HSP20) family
MW696_03005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MW696_03010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_03030	COG0824	Thioesterase
MW696_03040	COG4841	protein insertion into membrane
MW696_03045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MW696_03050	COG1832	CoA-binding protein
MW696_03055	COG0187	DNA topoisomerase II activity
MW696_03060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MW696_03065	COG1609	Transcriptional regulator
MW696_03080	COG2160	L-arabinose isomerase activity
MW696_03110	COG2181	nitrate reductase activity
MW696_03115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MW696_03120	COG1140	nitrate reductase beta subunit
MW696_03125	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MW696_03140	COG0535	radical SAM domain protein
MW696_03145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MW696_03155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MW696_03160	COG2223	nitrite transmembrane transporter activity
MW696_03180	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MW696_03190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MW696_03205	COG0574	Belongs to the PEP-utilizing enzyme family
MW696_03205	COG3848	Pyruvate phosphate dikinase
MW696_03215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MW696_03220	COG0798	PFAM Bile acid sodium symporter
MW696_03225	COG0640	Transcriptional regulator
MW696_03230	COG0693	protein deglycase activity
MW696_03270	COG1024	Enoyl-CoA hydratase
MW696_03275	COG1012	belongs to the aldehyde dehydrogenase family
MW696_03280	COG2084	Dehydrogenase
MW696_03285	COG1960	acyl-CoA dehydrogenase activity
MW696_03290	COG0789	Transcriptional regulator
MW696_03300	COG1064	alcohol dehydrogenase
MW696_03305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MW696_03310	COG2814	Major facilitator Superfamily
MW696_03315	COG1388	LysM domain
MW696_03320	COG2205	protein histidine kinase activity
MW696_03345	COG1595	DNA-templated transcription, initiation
MW696_03350	COG1482	cell wall glycoprotein biosynthetic process
MW696_03355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_03355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_03355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_03360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_03360	COG3711	transcriptional antiterminator
MW696_03365	COG0785	Cytochrome C biogenesis protein
MW696_03370	COG2814	Major facilitator Superfamily
MW696_03400	COG1725	Transcriptional regulator
MW696_03415	COG1309	transcriptional regulator
MW696_03445	COG2404	hydrolase activity, acting on ester bonds
MW696_03450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MW696_03455	COG1882	Formate acetyltransferase
MW696_03470	COG2027	D-alanyl-D-alanine carboxypeptidase
MW696_03475	COG1252	NADH dehydrogenase
MW696_03485	COG0166	Belongs to the GPI family
MW696_03495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MW696_03500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MW696_03505	COG1024	Enoyl-CoA hydratase
MW696_03510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MW696_03515	COG0511	ligase activity, forming carbon-carbon bonds
MW696_03520	COG0439	Biotin carboxylase
MW696_03525	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_03530	COG1960	acyl-CoA dehydrogenase activity
MW696_03535	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_03540	COG1733	regulation of RNA biosynthetic process
MW696_03580	COG2323	membrane
MW696_03585	COG0175	sulfate reduction
MW696_03590	COG1809	phosphosulfolactate synthase activity
MW696_03595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_03600	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_03605	COG2814	Major facilitator Superfamily
MW696_03610	COG0463	Glycosyl transferase, family 2
MW696_03625	COG0493	'glutamate synthase
MW696_03630	COG0069	glutamate synthase activity
MW696_03630	COG0070	glutamate synthase
MW696_03630	COG0067	glutamate synthase
MW696_03635	COG0583	DNA-binding transcription factor activity
MW696_03660	COG1132	(ABC) transporter
MW696_03665	COG3540	Alkaline phosphatase
MW696_03675	COG0300	oxidoreductase activity
MW696_03680	COG0477	Major facilitator Superfamily
MW696_03685	COG0243	molybdopterin cofactor binding
MW696_03690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MW696_03695	COG1846	Transcriptional regulator
MW696_03700	COG2814	Major facilitator Superfamily
MW696_03705	COG0531	amino acid
MW696_03715	COG0531	amino acid
MW696_03720	COG0531	amino acid
MW696_03725	COG0697	spore germination
MW696_03730	COG0488	(ABC) transporter
MW696_03750	COG0840	transmembrane signaling receptor activity
MW696_03755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_03760	COG1404	Belongs to the peptidase S8 family
MW696_03770	COG1309	transcriptional regulator
MW696_03780	COG1309	transcriptional regulator
MW696_03785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_03790	COG3708	Transcriptional regulator
MW696_03805	COG2378	regulation of single-species biofilm formation
MW696_03815	COG0640	Transcriptional regulator
MW696_03825	COG0531	amino acid
MW696_03830	COG0741	lytic transglycosylase activity
MW696_03835	COG1086	Polysaccharide biosynthesis protein
MW696_03855	COG2322	membrane
MW696_03865	COG1619	proteins homologs of microcin C7 resistance protein MccF
MW696_03870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_03875	COG1388	LysM domain
MW696_03885	COG3584	3D domain protein
MW696_03885	COG1388	LysM domain
MW696_03890	COG0514	ATP-dependent DNA helicase (RecQ)
MW696_03925	COG4282	regulation of fungal-type cell wall biogenesis
MW696_03970	COG5444	nuclease activity
MW696_03985	COG0457	Tetratricopeptide repeat
MW696_04010	COG0702	epimerase
MW696_04025	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_04030	COG1357	PFAM Pentapeptide repeats (8 copies)
MW696_04045	COG1280	lysine exporter protein (LysE YggA)
MW696_04050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MW696_04085	COG5634	Uncharacterized conserved protein (DUF2278)
MW696_04105	COG2318	DinB family
MW696_04110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MW696_04115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MW696_04120	COG2140	Oxalate decarboxylase
MW696_04140	COG0288	reversible hydration of carbon dioxide
MW696_04145	COG3002	Belongs to the UPF0753 family
MW696_04150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MW696_04155	COG5609	conserved protein (DUF2294)
MW696_04175	COG1012	belongs to the aldehyde dehydrogenase family
MW696_04195	COG0667	Aldo Keto reductase
MW696_04200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MW696_04205	COG1846	Transcriptional regulator
MW696_04210	COG1657	PFAM Prenyltransferase squalene oxidase
MW696_04215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MW696_04220	COG0733	neurotransmitter:sodium symporter activity
MW696_04225	COG0385	Bile acid
MW696_04230	COG0508	dehydrogenase complex catalyzes the overall conversion of
MW696_04235	COG0567	Dehydrogenase, E1 component
MW696_04240	COG4548	von Willebrand factor, type A
MW696_04245	COG0714	Associated with various cellular activities
MW696_04250	COG2032	superoxide dismutase activity
MW696_04255	COG0791	NLP P60 protein
MW696_04255	COG1388	LysM domain
MW696_04260	COG0534	Mate efflux family protein
MW696_04265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MW696_04270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MW696_04280	COG2962	Rard protein
MW696_04290	COG4305	rare lipoprotein A
MW696_04300	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_04305	COG1733	regulation of RNA biosynthetic process
MW696_04310	COG0778	Nitroreductase
MW696_04315	COG0400	carboxylic ester hydrolase activity
MW696_04320	COG0346	lactoylglutathione lyase activity
MW696_04330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_04335	COG3409	Peptidoglycan-binding domain 1 protein
MW696_04335	COG0793	Belongs to the peptidase S41A family
MW696_04340	COG2226	methyltransferase
MW696_04350	COG1876	peptidase activity
MW696_04355	COG0813	purine-nucleoside phosphorylase activity
MW696_04360	COG0701	Predicted permease
MW696_04380	COG0671	phosphoesterase, PA-phosphatase related
MW696_04400	COG4479	Belongs to the UPF0346 family
MW696_04410	COG1509	lysine 2,3-aminomutase activity
MW696_04415	COG0456	acetyltransferase
MW696_04420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MW696_04425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MW696_04430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MW696_04435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MW696_04445	COG0456	acetyltransferase
MW696_04450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MW696_04455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MW696_04460	COG1846	Transcriptional regulator
MW696_04470	COG0534	Mate efflux family protein
MW696_04485	COG4698	Protein conserved in bacteria
MW696_04490	COG2755	lipolytic protein G-D-S-L family
MW696_04495	COG1999	signal sequence binding
MW696_04510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MW696_04515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MW696_04520	COG1272	protein, Hemolysin III
MW696_04525	COG0204	Acyl-transferase
MW696_04530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MW696_04535	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MW696_04550	COG2521	methyltransferase
MW696_04550	COG2136	Putative SAM-dependent methyltransferase
MW696_04560	COG0129	dihydroxy-acid dehydratase activity
MW696_04565	COG1413	lyase activity
MW696_04570	COG1418	mRNA catabolic process
MW696_04575	COG0386	Belongs to the glutathione peroxidase family
MW696_04580	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MW696_04585	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MW696_04590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MW696_04600	COG1278	Cold shock
MW696_04620	COG0328	RNA-DNA hybrid ribonuclease activity
MW696_04625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MW696_04630	COG0328	RNA-DNA hybrid ribonuclease activity
MW696_04640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_04655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MW696_04665	COG1755	Isoprenylcysteine carboxyl methyltransferase
MW696_04670	COG3424	synthase
MW696_04680	COG2233	PERMEase
MW696_04685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MW696_04690	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MW696_04695	COG1199	ATP-dependent helicase activity
MW696_04710	COG0116	Belongs to the methyltransferase superfamily
MW696_04720	COG3599	regulation of cell shape
MW696_04725	COG4474	Belongs to the UPF0398 family
MW696_04735	COG3359	exonuclease
MW696_04740	COG1111	helicase
MW696_04740	COG1205	dead DEAH box helicase
MW696_04745	COG2190	(PTS) system
MW696_04750	COG0071	Belongs to the small heat shock protein (HSP20) family
MW696_04785	COG3331	DNA recombination
MW696_04790	COG4499	WXG100 protein secretion system (Wss), protein YukC
MW696_04790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MW696_04800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MW696_04805	COG3935	DnaD domain protein
MW696_04810	COG0017	Asparaginyl-tRNA synthetase
MW696_04815	COG0436	Aminotransferase
MW696_04820	COG5353	protein conserved in bacteria
MW696_04830	COG1199	ATP-dependent helicase activity
MW696_04830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MW696_04835	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MW696_04840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MW696_04845	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MW696_04855	COG0617	tRNA 3'-terminal CCA addition
MW696_04860	COG0438	transferase activity, transferring glycosyl groups
MW696_04865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MW696_04870	COG1803	Methylglyoxal synthase
MW696_04875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MW696_04880	COG1694	Mazg nucleotide pyrophosphohydrolase
MW696_04885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_04895	COG4347	Protein of unknown function (DUF1405)
MW696_04900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MW696_04900	COG2010	Cytochrome c
MW696_04905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MW696_04910	COG0723	plastoquinol--plastocyanin reductase activity
MW696_04920	COG5582	Belongs to the UPF0302 family
MW696_04925	COG0457	Tetratricopeptide repeat
MW696_04930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MW696_04935	COG0287	Prephenate dehydrogenase
MW696_04940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MW696_04945	COG0159	tryptophan synthase activity
MW696_04950	COG0133	tryptophan synthase activity
MW696_04955	COG0135	phosphoribosylanthranilate isomerase activity
MW696_04960	COG0134	indole-3-glycerol-phosphate synthase activity
MW696_04965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MW696_04970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MW696_04975	COG4401	Chorismate mutase type I
MW696_04980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MW696_04985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MW696_04990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MW696_04995	COG0105	UTP biosynthetic process
MW696_05000	COG0142	geranyltranstransferase activity
MW696_05005	COG2226	methyltransferase
MW696_05010	COG0142	geranyltranstransferase activity
MW696_05025	COG0776	regulation of translation
MW696_05030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MW696_05045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MW696_05050	COG1160	GTP binding
MW696_05075	COG1304	FMN binding
MW696_05080	COG0539	negative regulation of cytoplasmic translation
MW696_05085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MW696_05095	COG2959	enzyme of heme biosynthesis
MW696_05100	COG3409	Peptidoglycan-binding domain 1 protein
MW696_05100	COG3773	Cell wall hydrolase
MW696_05105	COG2339	peptidase activity
MW696_05115	COG0492	ferredoxin-NADP+ reductase activity
MW696_05120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MW696_05125	COG4862	establishment of competence for transformation
MW696_05130	COG1408	metallophosphoesterase
MW696_05140	COG1388	LysM domain
MW696_05145	COG1266	CAAX protease self-immunity
MW696_05150	COG0514	ATP-dependent DNA helicase (RecQ)
MW696_05155	COG4955	Helix-turn-helix domain
MW696_05160	COG1141	Ferredoxin
MW696_05165	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MW696_05170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MW696_05175	COG0739	heme binding
MW696_05185	COG1595	DNA-templated transcription, initiation
MW696_05205	COG5002	protein histidine kinase activity
MW696_05210	COG0745	RESPONSE REGULATOR receiver
MW696_05215	COG5002	protein histidine kinase activity
MW696_05220	COG0745	RESPONSE REGULATOR receiver
MW696_05225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MW696_05230	COG1333	cytochrome c biogenesis protein
MW696_05235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_05240	COG1187	pseudouridine synthase activity
MW696_05245	COG0700	Nucleoside recognition
MW696_05250	COG2715	membrane protein required for spore maturation
MW696_05255	COG1686	Belongs to the peptidase S11 family
MW696_05265	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MW696_05270	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MW696_05275	COG1547	Domain of unknown function (DUF309)
MW696_05280	COG0456	acetyltransferase
MW696_05285	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MW696_05290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MW696_05290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MW696_05295	COG0307	riboflavin synthase, alpha
MW696_05300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MW696_05300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MW696_05320	COG0457	Tetratricopeptide repeat
MW696_05325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MW696_05330	COG4086	secreted protein
MW696_05335	COG4195	phage-related replication protein
MW696_05345	COG0019	diaminopimelate decarboxylase activity
MW696_05355	COG0697	spore germination
MW696_05370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MW696_05405	COG1686	Belongs to the peptidase S11 family
MW696_05410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MW696_05415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MW696_05420	COG4974	Belongs to the 'phage' integrase family
MW696_05430	COG0735	belongs to the Fur family
MW696_05435	COG1300	Membrane
MW696_05440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_05455	COG4122	O-methyltransferase activity
MW696_05465	COG1379	DNA repair
MW696_05470	COG0494	nUDIX hydrolase
MW696_05480	COG1309	transcriptional regulator
MW696_05490	COG0667	Aldo Keto reductase
MW696_05495	COG0477	Major facilitator Superfamily
MW696_05500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_05505	COG3420	alginic acid biosynthetic process
MW696_05520	COG1073	alpha beta
MW696_05530	COG4918	Iron-sulphur cluster biosynthesis
MW696_05540	COG0456	acetyltransferase
MW696_05540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MW696_05550	COG0456	acetyltransferase
MW696_05560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MW696_05580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MW696_05595	COG2211	Major facilitator Superfamily
MW696_05600	COG0346	lactoylglutathione lyase activity
MW696_05605	COG1072	(Pantothenic acid kinase))
MW696_05615	COG1131	(ABC) transporter
MW696_05650	COG4195	phage-related replication protein
MW696_05655	COG0300	oxidoreductase activity
MW696_05660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_05665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MW696_05670	COG4187	Peptidase family M20/M25/M40
MW696_05675	COG1902	pentaerythritol trinitrate reductase activity
MW696_05680	COG0596	Alpha beta hydrolase
MW696_05685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MW696_05690	COG1234	tRNA 3'-trailer cleavage
MW696_05695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MW696_05700	COG2188	Transcriptional regulator
MW696_05705	COG2723	6-phospho-beta-galactosidase activity
MW696_05710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_05715	COG1447	Phosphotransferase system cellobiose-specific component IIA
MW696_05720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_05725	COG1785	Belongs to the alkaline phosphatase family
MW696_05730	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_05735	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MW696_05740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MW696_05750	COG0706	membrane insertase activity
MW696_05760	COG2195	Cleaves the N-terminal amino acid of tripeptides
MW696_05765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MW696_05775	COG4129	membrane
MW696_05780	COG1126	abc transporter atp-binding protein
MW696_05785	COG0765	amino acid transport
MW696_05790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_05800	COG1597	lipid kinase activity
MW696_05805	COG0508	dehydrogenase complex catalyzes the overall conversion of
MW696_05810	COG0022	dehydrogenase e1 component
MW696_05815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MW696_05820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MW696_05825	COG3426	butyrate kinase activity
MW696_05835	COG0280	phosphate acetyltransferase
MW696_05840	COG3290	protein histidine kinase activity
MW696_05840	COG3829	transcription factor binding
MW696_05850	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_05855	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MW696_05870	COG0745	RESPONSE REGULATOR receiver
MW696_05875	COG0750	zinc metalloprotease
MW696_05880	COG0497	DNA recombination
MW696_05885	COG1438	arginine binding
MW696_05890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MW696_05895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MW696_05900	COG0142	geranyltranstransferase activity
MW696_05905	COG1722	exodeoxyribonuclease VII activity
MW696_05910	COG1570	exodeoxyribonuclease VII activity
MW696_05915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MW696_05920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MW696_05925	COG1302	Protein conserved in bacteria
MW696_05930	COG0439	Biotin carboxylase
MW696_05935	COG0511	ligase activity, forming carbon-carbon bonds
MW696_05975	COG3854	ATPases associated with a variety of cellular activities
MW696_05990	COG0006	proline dipeptidase activity
MW696_05995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MW696_06005	COG3872	metal-dependent enzyme
MW696_06015	COG1752	Esterase of the alpha-beta hydrolase superfamily
MW696_06020	COG1321	iron dependent repressor
MW696_06030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_06035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MW696_06040	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MW696_06045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MW696_06050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MW696_06075	COG0681	Belongs to the peptidase S26 family
MW696_06100	COG4940	Competence protein ComGF
MW696_06110	COG4970	Tfp pilus assembly protein FimT
MW696_06115	COG4537	Required for transformation and DNA binding
MW696_06120	COG1459	type II secretion system
MW696_06125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MW696_06130	COG1366	Belongs to the anti-sigma-factor antagonist family
MW696_06140	COG1393	Belongs to the ArsC family
MW696_06150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_06160	COG0011	TIGRFAM Protein of
MW696_06170	COG2866	Carboxypeptidase
MW696_06175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_06185	COG2116	formate transmembrane transporter activity
MW696_06200	COG1368	sulfuric ester hydrolase activity
MW696_06205	COG1940	carbohydrate kinase activity
MW696_06210	COG4483	Protein conserved in bacteria
MW696_06215	COG0697	spore germination
MW696_06220	COG0705	Rhomboid family
MW696_06220	COG0457	Tetratricopeptide repeat
MW696_06230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MW696_06245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MW696_06250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MW696_06255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MW696_06260	COG0581	inorganic phosphate transmembrane transporter activity
MW696_06265	COG0573	inorganic phosphate transmembrane transporter activity
MW696_06270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MW696_06275	COG0768	penicillin binding
MW696_06280	COG0477	Major facilitator Superfamily
MW696_06285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MW696_06290	COG2839	Protein conserved in bacteria
MW696_06295	COG5521	maltodextrose utilization protein MalA
MW696_06300	COG1388	LysM domain
MW696_06305	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MW696_06310	COG4709	membrane
MW696_06315	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
MW696_06320	COG0735	belongs to the Fur family
MW696_06325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MW696_06330	COG1121	(ABC) transporter
MW696_06335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_06345	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MW696_06350	COG0513	Belongs to the DEAD box helicase family
MW696_06360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MW696_06365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MW696_06370	COG2384	SAM-dependent methyltransferase
MW696_06400	COG5444	nuclease activity
MW696_06410	COG2010	Cytochrome c
MW696_06415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MW696_06420	COG0358	DNA primase activity
MW696_06425	COG1671	Belongs to the UPF0178 family
MW696_06430	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MW696_06435	COG0517	IMP dehydrogenase activity
MW696_06440	COG0751	glycine-tRNA ligase activity
MW696_06445	COG0752	glycyl-tRNA synthetase alpha subunit
MW696_06450	COG1381	Involved in DNA repair and RecF pathway recombination
MW696_06460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MW696_06465	COG0295	cytidine deaminase activity
MW696_06470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MW696_06475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MW696_06480	COG1480	7TM receptor with intracellular HD hydrolase
MW696_06485	COG1702	phosphate starvation-inducible protein PhoH
MW696_06490	COG0561	phosphatase activity
MW696_06505	COG4864	UPF0365 protein
MW696_06510	COG1030	water channel activity
MW696_06515	COG1610	YqeY-like protein
MW696_06520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MW696_06525	COG1283	sodium-dependent phosphate transmembrane transporter activity
MW696_06530	COG1247	-acetyltransferase
MW696_06535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MW696_06540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MW696_06545	COG2264	protein methyltransferase activity
MW696_06550	COG0484	heat shock protein binding
MW696_06555	COG0443	Heat shock 70 kDa protein
MW696_06560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MW696_06565	COG1420	regulation of RNA biosynthetic process
MW696_06570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MW696_06575	COG0481	GTPase activity
MW696_06585	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_06590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MW696_06595	COG0268	Binds directly to 16S ribosomal RNA
MW696_06600	COG1466	dna polymerase III delta subunit
MW696_06610	COG0658	competence protein
MW696_06610	COG2333	competence protein COMEC
MW696_06615	COG2131	deaminase
MW696_06620	COG1555	photosystem II stabilization
MW696_06620	COG1596	polysaccharide export
MW696_06625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MW696_06630	COG2226	methyltransferase
MW696_06635	COG0799	negative regulation of ribosome biogenesis
MW696_06640	COG1713	HD superfamily hydrolase involved in NAD metabolism
MW696_06645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MW696_06650	COG1534	Rna-binding protein
MW696_06655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MW696_06660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MW696_06665	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MW696_06680	COG2755	lipolytic protein G-D-S-L family
MW696_06690	COG5609	conserved protein (DUF2294)
MW696_06695	COG3383	formate dehydrogenase (NAD+) activity
MW696_06700	COG2427	Protein of unknown function (DUF1641)
MW696_06720	COG0457	Tetratricopeptide repeat
MW696_06725	COG5444	nuclease activity
MW696_06755	COG1793	dna ligase
MW696_06830	COG0551	DNA topoisomerase type I activity
MW696_06830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MW696_06885	COG0739	heme binding
MW696_07005	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MW696_07095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MW696_07110	COG1309	transcriptional regulator
MW696_07115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MW696_07125	COG0730	response to heat
MW696_07130	COG0425	Belongs to the sulfur carrier protein TusA family
MW696_07135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_07135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_07140	COG2210	Belongs to the sulfur carrier protein TusA family
MW696_07145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_07145	COG0425	Belongs to the sulfur carrier protein TusA family
MW696_07155	COG2210	Belongs to the sulfur carrier protein TusA family
MW696_07160	COG1937	Protein conserved in bacteria
MW696_07165	COG1054	Belongs to the UPF0176 family
MW696_07175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MW696_07215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MW696_07230	COG0494	nUDIX hydrolase
MW696_07235	COG1733	regulation of RNA biosynthetic process
MW696_07240	COG0477	Major facilitator Superfamily
MW696_07245	COG2723	6-phospho-beta-galactosidase activity
MW696_07250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_07250	COG1263	PTS System
MW696_07250	COG2190	(PTS) system
MW696_07255	COG3711	transcriptional antiterminator
MW696_07260	COG1522	sequence-specific DNA binding
MW696_07265	COG1335	isochorismatase
MW696_07290	COG0697	spore germination
MW696_07300	COG0583	DNA-binding transcription factor activity
MW696_07305	COG2070	2-Nitropropane dioxygenase
MW696_07315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MW696_07320	COG0604	alcohol dehydrogenase
MW696_07325	COG2188	Transcriptional regulator
MW696_07345	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_07350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MW696_07355	COG3959	Transketolase, thiamine diphosphate binding domain
MW696_07375	COG0789	Transcriptional regulator
MW696_07375	COG4978	Transcriptional regulator
MW696_07410	COG0071	Belongs to the small heat shock protein (HSP20) family
MW696_07415	COG2409	Drug exporters of the RND superfamily
MW696_07420	COG2197	response regulator
MW696_07425	COG4585	Histidine kinase
MW696_07440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MW696_07445	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MW696_07450	COG1733	regulation of RNA biosynthetic process
MW696_07460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_07470	COG2197	response regulator
MW696_07475	COG4585	Histidine kinase
MW696_07485	COG0730	response to heat
MW696_07490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_07490	COG0425	Belongs to the sulfur carrier protein TusA family
MW696_07495	COG2210	Belongs to the sulfur carrier protein TusA family
MW696_07500	COG1937	Protein conserved in bacteria
MW696_07510	COG3239	Fatty acid desaturase
MW696_07515	COG4585	Histidine kinase
MW696_07520	COG2197	response regulator
MW696_07525	COG0492	ferredoxin-NADP+ reductase activity
MW696_07535	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_07540	COG1942	4-Oxalocrotonate Tautomerase
MW696_07555	COG3443	Belongs to the bacterial solute-binding protein 9 family
MW696_07565	COG2124	cytochrome p450
MW696_07570	COG2368	4-hydroxyphenylacetate
MW696_07580	COG0833	amino acid
MW696_07585	COG4187	Peptidase family M20/M25/M40
MW696_07590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MW696_07605	COG5583	Uncharacterized small protein (DUF2292)
MW696_07615	COG3507	Belongs to the glycosyl hydrolase 43 family
MW696_07625	COG1917	Cupin 2, conserved barrel domain protein
MW696_07625	COG4977	sequence-specific DNA binding
MW696_07635	COG1621	beta-fructofuranosidase activity
MW696_07640	COG3716	PTS system mannose fructose sorbose family IID component
MW696_07645	COG3715	PTS system
MW696_07650	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_07655	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_07660	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MW696_07660	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MW696_07675	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MW696_07690	COG1113	amino acid transport
MW696_07705	COG1525	nuclease
MW696_07720	COG2814	Major facilitator Superfamily
MW696_07730	COG2350	Protein conserved in bacteria
MW696_07740	COG2169	Transcriptional regulator
MW696_07745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MW696_07750	COG0656	L-ascorbic acid biosynthetic process
MW696_07755	COG2814	Major facilitator Superfamily
MW696_07760	COG1733	regulation of RNA biosynthetic process
MW696_07765	COG1587	Uroporphyrinogen-III synthase
MW696_07775	COG0583	DNA-binding transcription factor activity
MW696_07780	COG2814	Major facilitator Superfamily
MW696_07790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MW696_07790	COG2124	cytochrome p450
MW696_07795	COG1309	transcriptional regulator
MW696_07805	COG1404	Belongs to the peptidase S8 family
MW696_07810	COG2226	methyltransferase
MW696_07835	COG0626	cystathionine gamma-synthase activity
MW696_07840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MW696_07845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MW696_07850	COG2226	methyltransferase
MW696_07865	COG0768	penicillin binding
MW696_07870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MW696_07875	COG0572	uridine kinase
MW696_07880	COG0826	peptidase U32
MW696_07885	COG0826	peptidase U32
MW696_07890	COG4122	O-methyltransferase activity
MW696_07895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MW696_07900	COG3906	Belongs to the UPF0473 family
MW696_07905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MW696_07910	COG4472	Bacterial protein of unknown function (DUF965)
MW696_07915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MW696_07920	COG0628	permease
MW696_07925	COG1126	abc transporter atp-binding protein
MW696_07930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_07935	COG0765	amino acid transport
MW696_07940	COG0765	amino acid transport
MW696_07955	COG3881	PFAM PRC-barrel domain
MW696_07960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MW696_07965	COG0457	Tetratricopeptide repeat
MW696_07970	COG0482	sulfurtransferase activity
MW696_07975	COG1104	cysteine desulfurase activity
MW696_07980	COG1959	2 iron, 2 sulfur cluster binding
MW696_07985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MW696_07995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MW696_08005	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MW696_08010	COG0124	histidyl-tRNA synthetase
MW696_08020	COG3103	Sh3 type 3 domain protein
MW696_08020	COG4991	sh3 domain protein
MW696_08020	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_08025	COG1490	D-aminoacyl-tRNA deacylase activity
MW696_08030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MW696_08035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MW696_08040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MW696_08040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MW696_08045	COG5416	Lipopolysaccharide assembly protein A domain
MW696_08050	COG0490	domain, Protein
MW696_08055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MW696_08055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MW696_08065	COG2244	polysaccharide biosynthetic process
MW696_08070	COG2323	membrane
MW696_08080	COG1862	Preprotein translocase
MW696_08085	COG0343	queuine tRNA-ribosyltransferase activity
MW696_08090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MW696_08100	COG2255	four-way junction helicase activity
MW696_08105	COG0632	four-way junction helicase activity
MW696_08115	COG2112	serine threonine protein kinase
MW696_08125	COG2318	DinB family
MW696_08130	COG4195	phage-related replication protein
MW696_08145	COG0217	transcriptional regulatory protein
MW696_08155	COG1388	LysM domain
MW696_08160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MW696_08165	COG0157	Belongs to the NadC ModD family
MW696_08170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MW696_08180	COG1827	regulation of RNA biosynthetic process
MW696_08185	COG0077	Prephenate dehydratase
MW696_08190	COG4492	Belongs to the UPF0735 family
MW696_08195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MW696_08200	COG3290	protein histidine kinase activity
MW696_08205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MW696_08210	COG2868	ribosomal protein
MW696_08215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MW696_08220	COG1994	Peptidase M50
MW696_08225	COG0739	heme binding
MW696_08230	COG3832	glyoxalase III activity
MW696_08235	COG0640	Transcriptional regulator
MW696_08240	COG2894	cell division
MW696_08245	COG0850	regulation of cytokinetic process
MW696_08250	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MW696_08260	COG1077	Cell shape determining protein MreB Mrl
MW696_08265	COG2003	Belongs to the UPF0758 family
MW696_08270	COG0424	maF-like protein
MW696_08280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MW696_08285	COG0285	dihydrofolate synthase activity
MW696_08290	COG0525	valine-tRNA ligase activity
MW696_08300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MW696_08305	COG1388	LysM domain
MW696_08310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MW696_08315	COG0113	porphobilinogen synthase activity
MW696_08320	COG1587	Uroporphyrinogen-III synthase
MW696_08325	COG0181	hydroxymethylbilane synthase activity
MW696_08330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MW696_08335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MW696_08345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MW696_08350	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MW696_08355	COG0470	DNA polymerase III
MW696_08355	COG1067	ATP-dependent peptidase activity
MW696_08360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MW696_08365	COG0544	peptidyl-prolyl cis-trans isomerase activity
MW696_08370	COG0457	Tetratricopeptide repeat
MW696_08370	COG1477	protein flavinylation
MW696_08375	COG0066	3-isopropylmalate dehydratase activity
MW696_08380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MW696_08385	COG0473	3-isopropylmalate dehydrogenase activity
MW696_08390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MW696_08395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MW696_08400	COG0440	acetolactate synthase activity
MW696_08405	COG0028	Belongs to the TPP enzyme family
MW696_08410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MW696_08420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MW696_08445	COG5444	nuclease activity
MW696_08455	COG0622	Phosphoesterase
MW696_08460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MW696_08465	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MW696_08470	COG5401	PFAM Sporulation and spore germination
MW696_08475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MW696_08480	COG1846	Transcriptional regulator
MW696_08485	COG2197	response regulator
MW696_08490	COG4221	oxidoreductase activity
MW696_08495	COG0824	Thioesterase
MW696_08500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MW696_08505	COG1053	succinate dehydrogenase
MW696_08510	COG2009	succinate dehydrogenase
MW696_08515	COG1719	4-vinyl reductase, 4VR
MW696_08525	COG0527	aspartate kinase activity
MW696_08530	COG0322	excinuclease ABC activity
MW696_08535	COG3118	belongs to the thioredoxin family
MW696_08540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MW696_08545	COG2086	electron transfer activity
MW696_08550	COG1024	Enoyl-CoA hydratase
MW696_08555	COG1309	transcriptional regulator
MW696_08560	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_08565	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_08575	COG3766	membrane
MW696_08580	COG1193	negative regulation of DNA recombination
MW696_08585	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MW696_08585	COG1796	DNA polymerase
MW696_08590	COG1286	toxin biosynthetic process
MW696_08595	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MW696_08600	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MW696_08615	COG0072	phenylalanine-tRNA ligase activity
MW696_08615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_08620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MW696_08625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MW696_08635	COG1966	Carbon starvation protein
MW696_08640	COG1309	transcriptional regulator
MW696_08645	COG3402	PFAM membrane-flanked domain
MW696_08650	COG3428	Bacterial PH domain
MW696_08665	COG0395	ABC-type sugar transport system, permease component
MW696_08670	COG1175	transmembrane transport
MW696_08675	COG1653	transport
MW696_08680	COG0371	Dehydrogenase
MW696_08685	COG0235	Class ii aldolase
MW696_08690	COG1069	ribulokinase activity
MW696_08695	COG2160	L-arabinose isomerase activity
MW696_08705	COG1363	Peptidase, m42
MW696_08715	COG3326	Membrane
MW696_08720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MW696_08730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MW696_08735	COG1346	cytolysis
MW696_08740	COG1380	Effector of murein hydrolase LrgA
MW696_08745	COG3540	Alkaline phosphatase
MW696_08750	COG3279	Response regulator of the LytR AlgR family
MW696_08755	COG3275	phosphorelay sensor kinase activity
MW696_08760	COG1011	Hydrolase
MW696_08775	COG0398	Pfam SNARE associated Golgi protein
MW696_08780	COG1484	DNA-dependent DNA replication
MW696_08785	COG3611	Membrane attachment protein
MW696_08790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MW696_08800	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MW696_08805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MW696_08810	COG3866	Pectate lyase
MW696_08815	COG0237	dephospho-CoA kinase activity
MW696_08820	COG1971	Probably functions as a manganese efflux pump
MW696_08825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MW696_08830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_08830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_08835	COG5002	protein histidine kinase activity
MW696_08840	COG0745	RESPONSE REGULATOR receiver
MW696_08845	COG0039	L-malate dehydrogenase activity
MW696_08850	COG0538	isocitrate dehydrogenase activity
MW696_08855	COG0372	Belongs to the citrate synthase family
MW696_08860	COG2707	UPF0756 membrane protein
MW696_08865	COG0628	permease
MW696_08870	COG3030	protein affecting phage T7 exclusion by the F plasmid
MW696_08880	COG0205	6-phosphofructokinase activity
MW696_08885	COG0825	malonyl-CoA metabolic process
MW696_08890	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MW696_08895	COG0281	malic enzyme
MW696_08900	COG0587	DNA-directed DNA polymerase activity
MW696_08920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MW696_08930	COG4109	DRTGG domain
MW696_08935	COG1695	Transcriptional regulator
MW696_08940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MW696_08945	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_08955	COG0165	Argininosuccinate lyase
MW696_08960	COG0137	argininosuccinate synthase activity
MW696_08965	COG0521	Mo-molybdopterin cofactor biosynthetic process
MW696_08970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MW696_08975	COG0827	DNA restriction-modification system
MW696_08980	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MW696_08985	COG3874	Sporulation protein YtfJ
MW696_08995	COG1714	RDD family
MW696_09000	COG0616	signal peptide processing
MW696_09005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MW696_09015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MW696_09025	COG0301	tRNA thio-modification
MW696_09030	COG1104	cysteine desulfurase activity
MW696_09035	COG1114	Component of the transport system for branched-chain amino acids
MW696_09040	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MW696_09045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MW696_09050	COG1309	transcriptional regulator
MW696_09055	COG1956	GAF domain-containing protein
MW696_09060	COG2203	Gaf domain
MW696_09060	COG2199	diguanylate cyclase activity
MW696_09065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MW696_09085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MW696_09090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MW696_09095	COG0454	-acetyltransferase
MW696_09100	COG0517	IMP dehydrogenase activity
MW696_09105	COG0123	including yeast histone deacetylase and acetoin utilization protein
MW696_09110	COG1360	Flagellar Motor Protein
MW696_09115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MW696_09120	COG1609	Transcriptional regulator
MW696_09125	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MW696_09125	COG1605	Chorismate mutase
MW696_09135	COG3118	belongs to the thioredoxin family
MW696_09140	COG4980	gas vesicle protein
MW696_09145	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MW696_09150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MW696_09155	COG1674	ftsk spoiiie
MW696_09160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_09165	COG4848	Belongs to the UPF0354 family
MW696_09170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_09180	COG1363	Peptidase, m42
MW696_09185	COG5584	Small secreted protein
MW696_09190	COG0281	malic enzyme
MW696_09195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_09200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MW696_09210	COG0510	thiamine kinase activity
MW696_09215	COG1597	lipid kinase activity
MW696_09225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MW696_09230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MW696_09240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MW696_09245	COG2252	PERMEase
MW696_09250	COG1349	DNA-binding transcription factor activity
MW696_09255	COG1187	pseudouridine synthase activity
MW696_09260	COG2244	polysaccharide biosynthetic process
MW696_09265	COG2081	HI0933 family
MW696_09275	COG1349	DNA-binding transcription factor activity
MW696_09285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MW696_09300	COG0471	metal ion transport
MW696_09305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_09315	COG0457	Tetratricopeptide repeat
MW696_09325	COG5578	integral membrane protein
MW696_09330	COG0673	inositol 2-dehydrogenase activity
MW696_09335	COG1653	transport
MW696_09340	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MW696_09345	COG4209	transmembrane transport
MW696_09350	COG2207	Transcriptional regulator
MW696_09355	COG1653	transport
MW696_09360	COG0395	ABC-type sugar transport system, permease component
MW696_09365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MW696_09370	COG1073	alpha beta
MW696_09380	COG0583	DNA-binding transcription factor activity
MW696_09385	COG0346	lactoylglutathione lyase activity
MW696_09390	COG0495	leucyl-tRNA aminoacylation
MW696_09400	COG2814	Major facilitator Superfamily
MW696_09415	COG2433	Pfam Transposase IS66
MW696_09420	COG0577	efflux transmembrane transporter activity
MW696_09425	COG1136	(ABC) transporter
MW696_09435	COG1131	(ABC) transporter
MW696_09440	COG1725	Transcriptional regulator
MW696_09455	COG1242	4 iron, 4 sulfur cluster binding
MW696_09460	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MW696_09465	COG1301	dicarboxylic acid transport
MW696_09475	COG2267	carboxylic ester hydrolase activity
MW696_09480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MW696_09485	COG0671	phosphoesterase, PA-phosphatase related
MW696_09490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MW696_09490	COG0438	transferase activity, transferring glycosyl groups
MW696_09495	COG0367	asparagine synthase
MW696_09500	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MW696_09505	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MW696_09515	COG1506	peptidase
MW696_09520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MW696_09525	COG1116	anion transmembrane transporter activity
MW696_09530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MW696_09535	COG0494	nUDIX hydrolase
MW696_09550	COG4824	toxin secretion phage lysis holin
MW696_09555	COG0783	Belongs to the Dps family
MW696_09570	COG1854	S-ribosylhomocysteine lyase activity
MW696_09575	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MW696_09580	COG0288	reversible hydration of carbon dioxide
MW696_09585	COG0803	Belongs to the bacterial solute-binding protein 9 family
MW696_09590	COG0254	rRNA binding
MW696_09595	COG1271	oxidase subunit
MW696_09600	COG1294	oxidase, subunit
MW696_09615	COG2079	MmgE PrpD family protein
MW696_09620	COG1473	amidohydrolase
MW696_09625	COG1126	abc transporter atp-binding protein
MW696_09630	COG0765	amino acid transport
MW696_09635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_09640	COG0456	acetyltransferase
MW696_09645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_09650	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_09655	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_09660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MW696_09665	COG0596	Alpha beta hydrolase
MW696_09670	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MW696_09675	COG1169	isochorismate synthase
MW696_09680	COG1575	Belongs to the MenA family. Type 1 subfamily
MW696_09685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MW696_09785	COG0789	Transcriptional regulator
MW696_09795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MW696_09810	COG1609	Transcriptional regulator
MW696_09815	COG3859	Proton-coupled thiamine transporter YuaJ
MW696_09820	COG3764	Sortase (surface protein transpeptidase)
MW696_09835	COG0457	Tetratricopeptide repeat
MW696_09840	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MW696_09845	COG2318	DinB family
MW696_09855	COG1454	alcohol dehydrogenase
MW696_09860	COG1012	belongs to the aldehyde dehydrogenase family
MW696_09865	COG1510	regulation of RNA biosynthetic process
MW696_09870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MW696_09870	COG1017	nitric oxide dioxygenase activity
MW696_09895	COG1397	ADP-ribosylglycohydrolase
MW696_09900	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MW696_09955	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MW696_09970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MW696_09975	COG0726	polysaccharide deacetylase
MW696_09980	COG1408	metallophosphoesterase
MW696_09985	COG1968	undecaprenyl-diphosphatase activity
MW696_09990	COG0628	permease
MW696_09995	COG0673	inositol 2-dehydrogenase activity
MW696_10000	COG0840	transmembrane signaling receptor activity
MW696_10005	COG0840	transmembrane signaling receptor activity
MW696_10010	COG0840	transmembrane signaling receptor activity
MW696_10020	COG2070	2-Nitropropane dioxygenase
MW696_10025	COG0432	Pfam Uncharacterised protein family UPF0047
MW696_10030	COG0366	Alpha amylase catalytic
MW696_10035	COG5297	Belongs to the glycosyl hydrolase family 6
MW696_10040	COG1253	flavin adenine dinucleotide binding
MW696_10045	COG2738	Putative neutral zinc metallopeptidase
MW696_10060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MW696_10075	COG0166	Belongs to the GPI family
MW696_10080	COG1979	alcohol dehydrogenase
MW696_10085	COG2155	Conserved Protein
MW696_10090	COG1098	S1 RNA binding domain
MW696_10095	COG0436	Aminotransferase
MW696_10100	COG1522	sequence-specific DNA binding
MW696_10105	COG2267	carboxylic ester hydrolase activity
MW696_10115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MW696_10130	COG5018	Exonuclease
MW696_10135	COG2814	Major facilitator Superfamily
MW696_10140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MW696_10145	COG3011	Protein conserved in bacteria
MW696_10155	COG3290	protein histidine kinase activity
MW696_10160	COG4565	transcriptional regulatory protein
MW696_10165	COG1744	ABC transporter substrate-binding protein PnrA-like
MW696_10170	COG3845	ABC transporter
MW696_10175	COG4603	Belongs to the binding-protein-dependent transport system permease family
MW696_10180	COG1079	Belongs to the binding-protein-dependent transport system permease family
MW696_10185	COG1183	phosphatidylcholine synthase activity
MW696_10190	COG0586	Pfam SNARE associated Golgi protein
MW696_10195	COG0688	phosphatidylethanolamine metabolic process
MW696_10200	COG3493	citrate carrier protein
MW696_10210	COG2111	Na H antiporter
MW696_10210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MW696_10215	COG2111	Na H antiporter
MW696_10220	COG1006	Multisubunit Na H antiporter MnhC subunit
MW696_10225	COG0651	ATP synthesis coupled electron transport
MW696_10230	COG1863	multisubunit Na H antiporter MnhE subunit
MW696_10235	COG2212	antiporter activity
MW696_10240	COG1320	monovalent cation:proton antiporter activity
MW696_10245	COG2050	protein possibly involved in aromatic compounds catabolism
MW696_10250	COG2197	response regulator
MW696_10255	COG4585	Histidine kinase
MW696_10265	COG0142	geranyltranstransferase activity
MW696_10280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MW696_10285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MW696_10290	COG1335	isochorismatase
MW696_10295	COG5506	Protein of unknown function (DUF1694)
MW696_10310	COG0628	permease
MW696_10315	COG1959	2 iron, 2 sulfur cluster binding
MW696_10325	COG1418	mRNA catabolic process
MW696_10330	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_10345	COG1511	domain protein
MW696_10350	COG0433	COG0433 Predicted ATPase
MW696_10350	COG1674	ftsk spoiiie
MW696_10355	COG4499	WXG100 protein secretion system (Wss), protein YukC
MW696_10360	COG5417	Belongs to the EsaB family
MW696_10365	COG4842	Belongs to the WXG100 family
MW696_10370	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MW696_10370	COG2508	Transcriptional regulator
MW696_10375	COG0686	Belongs to the AlaDH PNT family
MW696_10380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MW696_10385	COG1268	BioY protein
MW696_10390	COG2056	Na+-H+ antiporter family
MW696_10395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MW696_10400	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MW696_10405	COG3584	3D domain protein
MW696_10420	COG1252	NADH dehydrogenase
MW696_10425	COG0492	ferredoxin-NADP+ reductase activity
MW696_10455	COG0316	Belongs to the HesB IscA family
MW696_10460	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MW696_10465	COG4844	belongs to the
MW696_10470	COG1252	NADH dehydrogenase
MW696_10485	COG0457	Tetratricopeptide repeat
MW696_10490	COG3479	Phenolic acid decarboxylase
MW696_10500	COG4837	Protein of unknown function (DUF1462)
MW696_10510	COG4946	Tricorn protease homolog
MW696_10510	COG0823	Involved in the tonB-independent uptake of proteins
MW696_10510	COG1506	peptidase
MW696_10515	COG0083	homoserine kinase activity
MW696_10520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MW696_10525	COG0460	homoserine dehydrogenase
MW696_10530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MW696_10535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MW696_10540	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MW696_10545	COG0647	UMP catabolic process
MW696_10550	COG2445	Protein of unknown function DUF86
MW696_10555	COG4470	Protein conserved in bacteria
MW696_10570	COG0739	heme binding
MW696_10580	COG3377	Domain of unknown function (DUF1805)
MW696_10585	COG0737	Belongs to the 5'-nucleotidase family
MW696_10590	COG0730	response to heat
MW696_10595	COG1801	Protein of unknown function DUF72
MW696_10605	COG3226	Transcriptional regulator
MW696_10610	COG2814	Major facilitator Superfamily
MW696_10615	COG2356	endonuclease I
MW696_10635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MW696_10640	COG2068	MobA-Related Protein
MW696_10645	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MW696_10650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MW696_10670	COG0719	Fe-S assembly protein
MW696_10675	COG0822	iron-sulfur transferase activity
MW696_10680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MW696_10685	COG0719	Fe-S assembly protein
MW696_10690	COG0396	ATPase activity
MW696_10705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MW696_10710	COG1464	Belongs to the NlpA lipoprotein family
MW696_10715	COG2011	ABC-type metal ion transport system permease component
MW696_10720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MW696_10730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_10735	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MW696_10745	COG0509	glycine decarboxylation via glycine cleavage system
MW696_10750	COG1393	Belongs to the ArsC family
MW696_10755	COG1960	acyl-CoA dehydrogenase activity
MW696_10760	COG0183	Belongs to the thiolase family
MW696_10765	COG1250	3-hydroxyacyl-CoA dehydrogenase
MW696_10765	COG1024	Enoyl-CoA hydratase
MW696_10780	COG5577	PFAM Coat F domain
MW696_10795	COG1120	ATPase activity
MW696_10800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_10805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_10810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_10825	COG1686	Belongs to the peptidase S11 family
MW696_10830	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_10835	COG0783	Belongs to the Dps family
MW696_10840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MW696_10845	COG0745	RESPONSE REGULATOR receiver
MW696_10850	COG2770	Histidine kinase
MW696_10850	COG2205	protein histidine kinase activity
MW696_10860	COG1309	transcriptional regulator
MW696_10865	COG0114	fumarate hydratase activity
MW696_10875	COG0697	spore germination
MW696_10880	COG0814	amino acid
MW696_10895	COG2197	response regulator
MW696_10900	COG4585	Histidine kinase
MW696_10905	COG4758	membrane
MW696_10915	COG1842	Phage shock protein A
MW696_10920	COG4758	membrane
MW696_10925	COG4677	pectinesterase activity
MW696_10935	COG0297	glycogen (starch) synthase activity
MW696_10940	COG2096	Adenosyltransferase
MW696_10945	COG1120	ATPase activity
MW696_10950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_10955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_10960	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_10965	COG2258	MOSC domain
MW696_10970	COG0583	DNA-binding transcription factor activity
MW696_10980	COG2721	sulfolactate sulfo-lyase activity
MW696_10985	COG0246	Mannitol dehydrogenase
MW696_10990	COG1609	Transcriptional regulator
MW696_10995	COG2211	Major facilitator Superfamily
MW696_11000	COG1904	glucuronate isomerase
MW696_11005	COG2205	protein histidine kinase activity
MW696_11010	COG0745	RESPONSE REGULATOR receiver
MW696_11015	COG1120	ATPase activity
MW696_11020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_11025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_11030	COG0531	amino acid
MW696_11040	COG1988	membrane-bound metal-dependent
MW696_11045	COG1368	sulfuric ester hydrolase activity
MW696_11050	COG2814	Major facilitator Superfamily
MW696_11055	COG0656	L-ascorbic acid biosynthetic process
MW696_11060	COG1940	carbohydrate kinase activity
MW696_11070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MW696_11080	COG3973	AAA domain
MW696_11085	COG2860	membrane
MW696_11090	COG0456	acetyltransferase
MW696_11090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MW696_11095	COG0456	acetyltransferase
MW696_11100	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MW696_11105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MW696_11110	COG2217	Heavy metal translocating P-type atpase
MW696_11125	COG1175	transmembrane transport
MW696_11130	COG0395	ABC-type sugar transport system, permease component
MW696_11135	COG1501	Belongs to the glycosyl hydrolase 31 family
MW696_11140	COG1472	Belongs to the glycosyl hydrolase 3 family
MW696_11145	COG1121	(ABC) transporter
MW696_11150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MW696_11155	COG0803	Belongs to the bacterial solute-binding protein 9 family
MW696_11165	COG1105	Belongs to the carbohydrate kinase PfkB family
MW696_11170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_11170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_11170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_11185	COG2217	Heavy metal translocating P-type atpase
MW696_11190	COG2608	mercury ion transmembrane transporter activity
MW696_11195	COG1937	Protein conserved in bacteria
MW696_11200	COG0693	protein deglycase activity
MW696_11205	COG1349	DNA-binding transcription factor activity
MW696_11210	COG1070	Carbohydrate kinase
MW696_11215	COG4952	isomerase
MW696_11225	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_11225	COG3347	Dehydrogenase
MW696_11230	COG2814	Major facilitator Superfamily
MW696_11235	COG3340	Belongs to the peptidase S51 family
MW696_11240	COG2814	Major facilitator Superfamily
MW696_11245	COG1846	Transcriptional regulator
MW696_11250	COG1819	glycosyl
MW696_11255	COG0673	inositol 2-dehydrogenase activity
MW696_11260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MW696_11265	COG1054	Belongs to the UPF0176 family
MW696_11275	COG1191	sigma factor activity
MW696_11285	COG2140	Oxalate decarboxylase
MW696_11300	COG5520	Belongs to the glycosyl hydrolase 30 family
MW696_11305	COG3507	Belongs to the glycosyl hydrolase 43 family
MW696_11315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MW696_11320	COG0557	exoribonuclease II activity
MW696_11325	COG1647	Serine aminopeptidase, S33
MW696_11330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MW696_11335	COG2002	toxin-antitoxin pair type II binding
MW696_11340	COG1476	TRANSCRIPTIONal
MW696_11345	COG1396	sequence-specific DNA binding
MW696_11350	COG1396	sequence-specific DNA binding
MW696_11355	COG1174	glycine betaine transport
MW696_11360	COG1732	Glycine betaine
MW696_11365	COG1174	glycine betaine transport
MW696_11370	COG0517	IMP dehydrogenase activity
MW696_11370	COG1125	glycine betaine transport
MW696_11375	COG1510	regulation of RNA biosynthetic process
MW696_11380	COG2095	MarC family integral membrane protein
MW696_11385	COG3064	Membrane
MW696_11390	COG4640	response to antibiotic
MW696_11395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_11405	COG0148	phosphopyruvate hydratase activity
MW696_11410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MW696_11415	COG0149	triose-phosphate isomerase activity
MW696_11420	COG0126	phosphoglycerate kinase activity
MW696_11425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MW696_11430	COG2390	Transcriptional regulator
MW696_11440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_11445	COG1113	amino acid transport
MW696_11455	COG1881	PFAM PEBP family protein
MW696_11465	COG4585	Histidine kinase
MW696_11470	COG2197	response regulator
MW696_11480	COG1131	(ABC) transporter
MW696_11490	COG4978	Transcriptional regulator
MW696_11490	COG0789	Transcriptional regulator
MW696_11500	COG1556	Lactate utilization protein
MW696_11505	COG1139	Iron-sulfur cluster binding protein
MW696_11510	COG0247	lactate metabolic process
MW696_11515	COG2186	Transcriptional regulator
MW696_11520	COG1620	l-lactate permease
MW696_11525	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MW696_11535	COG5039	Polysaccharide pyruvyl transferase
MW696_11540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MW696_11545	COG0110	maltose O-acetyltransferase activity
MW696_11550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MW696_11555	COG2244	polysaccharide biosynthetic process
MW696_11560	COG1216	Glycosyl transferase, family 2
MW696_11565	COG5039	Polysaccharide pyruvyl transferase
MW696_11570	COG1216	Glycosyl transferase, family 2
MW696_11580	COG0438	transferase activity, transferring glycosyl groups
MW696_11585	COG1215	transferase activity, transferring glycosyl groups
MW696_11590	COG0438	transferase activity, transferring glycosyl groups
MW696_11595	COG1086	Polysaccharide biosynthesis protein
MW696_11600	COG0489	protein tyrosine kinase activity
MW696_11605	COG3944	biosynthesis protein
MW696_11610	COG1396	sequence-specific DNA binding
MW696_11615	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_11620	COG2271	Major facilitator Superfamily
MW696_11630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MW696_11640	COG1454	alcohol dehydrogenase
MW696_11645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MW696_11655	COG1733	regulation of RNA biosynthetic process
MW696_11660	COG1902	pentaerythritol trinitrate reductase activity
MW696_11665	COG1621	beta-fructofuranosidase activity
MW696_11670	COG1621	beta-fructofuranosidase activity
MW696_11690	COG0457	Tetratricopeptide repeat
MW696_11695	COG0457	Tetratricopeptide repeat
MW696_11700	COG5444	nuclease activity
MW696_11735	COG5632	N-Acetylmuramoyl-L-alanine amidase
MW696_11735	COG3409	Peptidoglycan-binding domain 1 protein
MW696_11735	COG1388	LysM domain
MW696_11755	COG5434	Belongs to the glycosyl hydrolase 28 family
MW696_11855	COG0582	viral genome integration into host DNA
MW696_11955	COG3584	3D domain protein
MW696_11960	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
MW696_11985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MW696_12000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MW696_12010	COG1780	Probably involved in ribonucleotide reductase function
MW696_12025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MW696_12045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_12045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_12180	COG4974	Belongs to the 'phage' integrase family
MW696_12190	COG0740	serine-type endopeptidase activity
MW696_12200	COG1611	Belongs to the LOG family
MW696_12205	COG1694	Mazg nucleotide pyrophosphohydrolase
MW696_12210	COG1078	dGTPase activity
MW696_12215	COG0659	secondary active sulfate transmembrane transporter activity
MW696_12220	COG0288	reversible hydration of carbon dioxide
MW696_12225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MW696_12230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MW696_12235	COG0640	Transcriptional regulator
MW696_12240	COG0577	efflux transmembrane transporter activity
MW696_12245	COG1136	(ABC) transporter
MW696_12250	COG5002	protein histidine kinase activity
MW696_12255	COG0745	RESPONSE REGULATOR receiver
MW696_12260	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MW696_12265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_12270	COG1481	regulation of sporulation
MW696_12275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MW696_12280	COG1660	Displays ATPase and GTPase activities
MW696_12285	COG1051	belongs to the nudix hydrolase family
MW696_12290	COG0492	ferredoxin-NADP+ reductase activity
MW696_12295	COG0457	Tetratricopeptide repeat
MW696_12300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MW696_12300	COG0140	phosphoribosyl-ATP diphosphatase activity
MW696_12305	COG0107	imidazoleglycerol-phosphate synthase activity
MW696_12310	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MW696_12315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MW696_12320	COG0131	Imidazoleglycerol-phosphate dehydratase
MW696_12325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MW696_12330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MW696_12335	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MW696_12340	COG4990	cell redox homeostasis
MW696_12345	COG3858	chitin binding
MW696_12350	COG5297	Belongs to the glycosyl hydrolase family 6
MW696_12355	COG0110	maltose O-acetyltransferase activity
MW696_12360	COG0546	phosphoglycolate phosphatase activity
MW696_12365	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MW696_12370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MW696_12375	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MW696_12380	COG1846	Transcriptional regulator
MW696_12385	COG2814	Major facilitator Superfamily
MW696_12390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MW696_12395	COG1950	PFAM Membrane protein of
MW696_12400	COG1983	PspC domain protein
MW696_12405	COG3595	metallopeptidase activity
MW696_12420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MW696_12425	COG0556	nucleotide-excision repair
MW696_12430	COG4897	Protein conserved in bacteria
MW696_12440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MW696_12450	COG0793	Belongs to the peptidase S41A family
MW696_12450	COG3409	Peptidoglycan-binding domain 1 protein
MW696_12455	COG0473	3-isopropylmalate dehydrogenase activity
MW696_12460	COG0791	NLP P60 protein
MW696_12460	COG3883	PFAM NLP P60 protein
MW696_12465	COG2177	Part of the ABC transporter FtsEX involved in
MW696_12470	COG2884	Cell division ATP-binding protein ftsE
MW696_12475	COG2010	Cytochrome c
MW696_12480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_12490	COG0653	protein targeting
MW696_12495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MW696_12510	COG1516	flagellar protein fliS
MW696_12515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MW696_12520	COG1334	flagellar protein FlaG
MW696_12525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MW696_12530	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MW696_12535	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MW696_12545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MW696_12550	COG1256	bacterial-type flagellum assembly
MW696_12550	COG4786	Flagellar basal body rod
MW696_12555	COG3418	PFAM FlgN family protein
MW696_12560	COG2747	anti-sigma28 factor FlgM
MW696_12570	COG1040	competence protein
MW696_12580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MW696_12585	COG1307	EDD domain protein, DegV family
MW696_12590	COG2197	response regulator
MW696_12595	COG4585	Histidine kinase
MW696_12600	COG1739	Uncharacterized protein family UPF0029
MW696_12605	COG1316	TRANSCRIPTIONal
MW696_12610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MW696_12615	COG0438	transferase activity, transferring glycosyl groups
MW696_12620	COG1215	transferase activity, transferring glycosyl groups
MW696_12625	COG3206	protein involved in exopolysaccharide biosynthesis
MW696_12630	COG3307	-O-antigen
MW696_12635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MW696_12640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MW696_12645	COG0297	glycogen (starch) synthase activity
MW696_12645	COG0438	transferase activity, transferring glycosyl groups
MW696_12650	COG2244	polysaccharide biosynthetic process
MW696_12660	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_12660	COG2247	cell wall binding repeat
MW696_12665	COG2385	sporulation resulting in formation of a cellular spore
MW696_12665	COG2247	cell wall binding repeat
MW696_12675	COG1316	TRANSCRIPTIONal
MW696_12680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MW696_12685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MW696_12690	COG1134	teichoic acid transport
MW696_12695	COG1682	transport, permease protein
MW696_12700	COG1215	transferase activity, transferring glycosyl groups
MW696_12715	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MW696_12725	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MW696_12730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MW696_12740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MW696_12745	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MW696_12750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MW696_12755	COG4193	domain, Protein
MW696_12760	COG1482	cell wall glycoprotein biosynthetic process
MW696_12770	COG1328	CTP reductase activity
MW696_12780	COG0800	Aldolase
MW696_12785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MW696_12790	COG1609	Transcriptional regulator
MW696_12795	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MW696_12800	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_12805	COG1063	alcohol dehydrogenase
MW696_12815	COG2814	Major facilitator Superfamily
MW696_12820	COG1316	TRANSCRIPTIONal
MW696_12825	COG0561	phosphatase activity
MW696_12830	COG0791	NLP P60 protein
MW696_12840	COG2843	Capsule synthesis protein
MW696_12850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MW696_12855	COG1609	Transcriptional regulator
MW696_12860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MW696_12865	COG1869	D-ribose catabolic process
MW696_12870	COG1129	ABC transporter
MW696_12875	COG1172	Belongs to the binding-protein-dependent transport system permease family
MW696_12880	COG1879	ABC-type sugar transport system periplasmic component
MW696_12885	COG0583	DNA-binding transcription factor activity
MW696_12890	COG2226	methyltransferase
MW696_12895	COG3527	Alpha-acetolactate decarboxylase
MW696_12900	COG0028	Belongs to the TPP enzyme family
MW696_12905	COG0583	DNA-binding transcription factor activity
MW696_12915	COG1522	sequence-specific DNA binding
MW696_12920	COG2059	Chromate
MW696_12925	COG2059	Chromate
MW696_12930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MW696_12935	COG4464	protein tyrosine phosphatase activity
MW696_12940	COG3944	biosynthesis protein
MW696_12950	COG4715	Zinc finger, swim domain protein
MW696_12955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MW696_12960	COG0831	urea catabolic process
MW696_12965	COG0832	Belongs to the urease beta subunit family
MW696_12970	COG0804	urea catabolic process
MW696_12975	COG0561	phosphatase activity
MW696_12980	COG1349	DNA-binding transcription factor activity
MW696_12985	COG0629	single-stranded DNA binding
MW696_13000	COG1970	mechanosensitive ion channel activity
MW696_13005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MW696_13010	COG4786	Flagellar basal body rod
MW696_13015	COG4786	Flagellar basal body rod
MW696_13020	COG1077	Cell shape determining protein MreB Mrl
MW696_13025	COG1609	Transcriptional regulator
MW696_13030	COG1846	Transcriptional regulator
MW696_13035	COG2814	Major facilitator Superfamily
MW696_13040	COG0671	phosphoesterase, PA-phosphatase related
MW696_13045	COG1227	inorganic diphosphatase activity
MW696_13050	COG3546	catalase activity
MW696_13055	COG3361	conserved protein (COG2071)
MW696_13060	COG0517	IMP dehydrogenase activity
MW696_13065	COG0598	Magnesium transport protein CorA
MW696_13070	COG1253	flavin adenine dinucleotide binding
MW696_13075	COG0004	ammonium transporteR
MW696_13080	COG0347	Belongs to the P(II) protein family
MW696_13090	COG0740	serine-type endopeptidase activity
MW696_13100	COG0739	heme binding
MW696_13105	COG1247	-acetyltransferase
MW696_13115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MW696_13120	COG0477	Major facilitator Superfamily
MW696_13125	COG3251	PFAM MbtH domain protein
MW696_13130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_13135	COG3433	isochorismatase activity
MW696_13135	COG1535	isochorismatase
MW696_13140	COG1021	2,3-dihydroxybenzoate-AMP ligase
MW696_13145	COG1169	isochorismate synthase
MW696_13150	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_13155	COG2819	hydrolase of the alpha beta superfamily
MW696_13160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_13165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_13170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_13175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_13175	COG2207	Transcriptional regulator
MW696_13185	COG2910	NAD(P)H-binding
MW696_13190	COG1959	2 iron, 2 sulfur cluster binding
MW696_13200	COG1994	Peptidase M50
MW696_13205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MW696_13210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MW696_13215	COG2223	nitrite transmembrane transporter activity
MW696_13225	COG2304	oxidoreductase activity
MW696_13230	COG2304	oxidoreductase activity
MW696_13235	COG2385	sporulation resulting in formation of a cellular spore
MW696_13240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MW696_13250	COG4836	Membrane
MW696_13255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MW696_13260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MW696_13265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MW696_13270	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MW696_13275	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MW696_13280	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MW696_13285	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MW696_13300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MW696_13305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MW696_13310	COG4475	Protein of unknown function (DUF436)
MW696_13315	COG0698	ribose 5-phosphate isomerase
MW696_13320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MW696_13325	COG1971	Probably functions as a manganese efflux pump
MW696_13330	COG0009	L-threonylcarbamoyladenylate synthase
MW696_13335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MW696_13345	COG0738	Major facilitator superfamily
MW696_13350	COG0673	inositol 2-dehydrogenase activity
MW696_13355	COG0561	phosphatase activity
MW696_13360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MW696_13365	COG1609	Transcriptional regulator
MW696_13370	COG2890	protein-(glutamine-N5) methyltransferase activity
MW696_13375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MW696_13380	COG0346	lactoylglutathione lyase activity
MW696_13385	COG0789	Transcriptional regulator
MW696_13390	COG0679	Auxin Efflux Carrier
MW696_13395	COG0281	malic enzyme
MW696_13400	COG1435	thymidine kinase activity
MW696_13410	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MW696_13415	COG1494	fructose-1,6-bisphosphatase
MW696_13420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MW696_13425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MW696_13430	COG0191	fructose-bisphosphate aldolase activity
MW696_13435	COG2204	response regulator
MW696_13440	COG4821	SIS domain
MW696_13445	COG0504	CTP synthase activity
MW696_13450	COG3343	RNA polymerase activity
MW696_13455	COG1960	acyl-CoA dehydrogenase activity
MW696_13460	COG1960	acyl-CoA dehydrogenase activity
MW696_13465	COG1250	3-hydroxyacyl-CoA dehydrogenase
MW696_13470	COG0183	Belongs to the thiolase family
MW696_13475	COG0247	lactate metabolic process
MW696_13475	COG2181	nitrate reductase activity
MW696_13495	COG0018	arginyl-trna synthetase
MW696_13500	COG4506	Protein conserved in bacteria
MW696_13505	COG0010	Belongs to the arginase family
MW696_13510	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MW696_13515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MW696_13525	COG1994	Peptidase M50
MW696_13530	COG1942	4-Oxalocrotonate Tautomerase
MW696_13540	COG3465	dGTPase activity
MW696_13545	COG1078	dGTPase activity
MW696_13550	COG4844	belongs to the
MW696_13575	COG2814	Major facilitator Superfamily
MW696_13600	COG1414	Transcriptional regulator
MW696_13610	COG0280	phosphate acetyltransferase
MW696_13615	COG3253	May function as heme-dependent peroxidase
MW696_13640	COG1131	(ABC) transporter
MW696_13650	COG2197	response regulator
MW696_13655	COG2363	Small membrane protein
MW696_13660	COG2233	PERMEase
MW696_13670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MW696_13675	COG1216	Glycosyl transferase, family 2
MW696_13680	COG0351	phosphomethylpyrimidine kinase
MW696_13690	COG1621	beta-fructofuranosidase activity
MW696_13695	COG1263	PTS System
MW696_13695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_13700	COG3711	transcriptional antiterminator
MW696_13710	COG1404	Belongs to the peptidase S8 family
MW696_13720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_13730	COG0778	Nitroreductase
MW696_13735	COG1473	amidohydrolase
MW696_13740	COG0772	Belongs to the SEDS family
MW696_13745	COG0772	Belongs to the SEDS family
MW696_13750	COG3314	Sporulation integral membrane protein YlbJ
MW696_13790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MW696_13800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MW696_13805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MW696_13810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MW696_13825	COG0655	NAD(P)H dehydrogenase (quinone) activity
MW696_13830	COG3162	membrane
MW696_13835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_13840	COG1070	Carbohydrate kinase
MW696_13845	COG2115	Belongs to the xylose isomerase family
MW696_13855	COG0352	thiamine-phosphate diphosphorylase activity
MW696_13860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MW696_13865	COG0583	DNA-binding transcription factor activity
MW696_13880	COG1380	Effector of murein hydrolase LrgA
MW696_13885	COG1346	cytolysis
MW696_13890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_13895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MW696_13900	COG0346	lactoylglutathione lyase activity
MW696_13905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MW696_13910	COG1442	glycosyl transferase family 8
MW696_13915	COG5522	Integral membrane protein (intg_mem_TP0381)
MW696_13920	COG2271	Major facilitator Superfamily
MW696_13925	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_13930	COG0800	Aldolase
MW696_13935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MW696_13940	COG1414	Transcriptional regulator
MW696_13945	COG2234	aminopeptidase activity
MW696_13965	COG0477	Major facilitator Superfamily
MW696_13970	COG1335	isochorismatase
MW696_13975	COG2357	RelA SpoT domain protein
MW696_13990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_13995	COG1696	Membrane protein involved in D-alanine export
MW696_14000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MW696_14005	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MW696_14010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MW696_14015	COG2814	Major facilitator Superfamily
MW696_14020	COG1486	melibiose metabolic process
MW696_14025	COG1447	Phosphotransferase system cellobiose-specific component IIA
MW696_14030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_14035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_14040	COG3711	transcriptional antiterminator
MW696_14040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_14045	COG2094	Belongs to the DNA glycosylase MPG family
MW696_14070	COG0372	Belongs to the citrate synthase family
MW696_14075	COG2079	MmgE PrpD family protein
MW696_14080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MW696_14085	COG1132	(ABC) transporter
MW696_14090	COG2755	lipolytic protein G-D-S-L family
MW696_14110	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MW696_14115	COG1131	(ABC) transporter
MW696_14135	COG1595	DNA-templated transcription, initiation
MW696_14140	COG2814	Major facilitator Superfamily
MW696_14150	COG0753	catalase activity
MW696_14160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MW696_14170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MW696_14175	COG2311	Membrane
MW696_14180	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MW696_14185	COG4988	ABC transporter
MW696_14190	COG1294	oxidase, subunit
MW696_14195	COG1271	oxidase subunit
MW696_14200	COG3001	Fructosamine kinase
MW696_14205	COG2116	formate transmembrane transporter activity
MW696_14215	COG0281	malic enzyme
MW696_14220	COG1757	Na H antiporter
MW696_14225	COG1027	Aspartate ammonia-lyase
MW696_14230	COG0252	asparaginase activity
MW696_14235	COG1396	sequence-specific DNA binding
MW696_14240	COG2706	6-phosphogluconolactonase activity
MW696_14245	COG0745	RESPONSE REGULATOR receiver
MW696_14260	COG5294	Protein conserved in bacteria
MW696_14275	COG0726	polysaccharide deacetylase
MW696_14280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_14295	COG3493	citrate carrier protein
MW696_14300	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_14320	COG5444	nuclease activity
MW696_14330	COG1368	sulfuric ester hydrolase activity
MW696_14345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_14350	COG1438	arginine binding
MW696_14355	COG2235	arginine
MW696_14360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MW696_14370	COG0549	Belongs to the carbamate kinase family
MW696_14380	COG2205	protein histidine kinase activity
MW696_14385	COG2723	6-phospho-beta-galactosidase activity
MW696_14390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_14400	COG1595	DNA-templated transcription, initiation
MW696_14410	COG2195	Cleaves the N-terminal amino acid of tripeptides
MW696_14420	COG1621	beta-fructofuranosidase activity
MW696_14425	COG2223	nitrite transmembrane transporter activity
MW696_14430	COG1609	Transcriptional regulator
MW696_14445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MW696_14450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MW696_14455	COG0463	Glycosyl transferase, family 2
MW696_14460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MW696_14470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MW696_14475	COG1476	TRANSCRIPTIONal
MW696_14480	COG0693	protein deglycase activity
MW696_14480	COG0753	catalase activity
MW696_14485	COG2851	Citrate transporter
MW696_14490	COG2723	6-phospho-beta-galactosidase activity
MW696_14500	COG3711	transcriptional antiterminator
MW696_14505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MW696_14510	COG1122	ATPase activity
MW696_14515	COG4721	ABC-type cobalt transport system, permease component
MW696_14520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MW696_14535	COG2224	Isocitrate lyase
MW696_14540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MW696_14550	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MW696_14555	COG0577	efflux transmembrane transporter activity
MW696_14560	COG1136	(ABC) transporter
MW696_14565	COG2205	protein histidine kinase activity
MW696_14570	COG0745	RESPONSE REGULATOR receiver
MW696_14575	COG2723	6-phospho-beta-galactosidase activity
MW696_14580	COG1263	PTS System
MW696_14580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_14580	COG2190	(PTS) system
MW696_14590	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MW696_14605	COG0513	Belongs to the DEAD box helicase family
MW696_14610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MW696_14615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MW696_14620	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MW696_14625	COG2390	Transcriptional regulator
MW696_14630	COG0457	Tetratricopeptide repeat
MW696_14635	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MW696_14640	COG3706	GGDEF domain
MW696_14650	COG1215	transferase activity, transferring glycosyl groups
MW696_14660	COG3977	Valine--pyruvate aminotransferase
MW696_14675	COG1181	Belongs to the D-alanine--D-alanine ligase family
MW696_14685	COG0191	fructose-bisphosphate aldolase activity
MW696_14690	COG1082	Xylose isomerase domain protein TIM barrel
MW696_14695	COG1082	Xylose isomerase domain protein TIM barrel
MW696_14700	COG0673	inositol 2-dehydrogenase activity
MW696_14705	COG2814	Major facilitator Superfamily
MW696_14710	COG1082	Xylose isomerase domain protein TIM barrel
MW696_14715	COG3962	Belongs to the TPP enzyme family
MW696_14720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MW696_14725	COG3718	enzyme involved in inositol metabolism
MW696_14730	COG1012	belongs to the aldehyde dehydrogenase family
MW696_14735	COG1349	DNA-binding transcription factor activity
MW696_14740	COG0667	Aldo Keto reductase
MW696_14745	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_14750	COG2271	Major facilitator Superfamily
MW696_14755	COG0326	Molecular chaperone. Has ATPase activity
MW696_14760	COG0488	(ABC) transporter
MW696_14765	COG0561	phosphatase activity
MW696_14785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_14810	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MW696_14815	COG0577	efflux transmembrane transporter activity
MW696_14820	COG1136	(ABC) transporter
MW696_14825	COG2205	protein histidine kinase activity
MW696_14830	COG0745	RESPONSE REGULATOR receiver
MW696_14840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_14845	COG3867	Arabinogalactan endo-beta-1,4-galactanase
MW696_14850	COG1874	Beta-galactosidase
MW696_14855	COG3833	ABC-type maltose transport systems, permease component
MW696_14860	COG1175	transmembrane transport
MW696_14865	COG2182	Extracellular solute-binding protein
MW696_14870	COG1609	Transcriptional regulator
MW696_14880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MW696_14885	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MW696_14890	COG1940	carbohydrate kinase activity
MW696_14895	COG1802	Transcriptional regulator
MW696_14900	COG1070	Carbohydrate kinase
MW696_14905	COG2610	gluconate transmembrane transporter activity
MW696_14915	COG1454	alcohol dehydrogenase
MW696_14915	COG1012	belongs to the aldehyde dehydrogenase family
MW696_14925	COG0450	alkyl hydroperoxide reductase
MW696_14930	COG3634	alkyl hydroperoxide reductase activity
MW696_14935	COG1113	amino acid transport
MW696_14955	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MW696_14980	COG1131	(ABC) transporter
MW696_14985	COG0842	Transport permease protein
MW696_14990	COG4585	Histidine kinase
MW696_14995	COG2197	response regulator
MW696_15005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MW696_15010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MW696_15025	COG0456	acetyltransferase
MW696_15040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MW696_15045	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MW696_15050	COG4853	Protein conserved in bacteria
MW696_15055	COG4863	YycH protein
MW696_15060	COG5002	protein histidine kinase activity
MW696_15065	COG0745	RESPONSE REGULATOR receiver
MW696_15090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MW696_15100	COG0305	Participates in initiation and elongation during chromosome replication
MW696_15110	COG3093	addiction module antidote protein HigA
MW696_15115	COG2807	transmembrane transport
MW696_15120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MW696_15125	COG0363	glucosamine-6-phosphate deaminase activity
MW696_15130	COG2188	Transcriptional regulator
MW696_15135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MW696_15140	COG1263	PTS System
MW696_15140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_15145	COG0359	binds to the 23S rRNA
MW696_15150	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MW696_15155	COG4241	membrane
MW696_15165	COG5577	PFAM Coat F domain
MW696_15170	COG0659	secondary active sulfate transmembrane transporter activity
MW696_15175	COG2271	Major facilitator Superfamily
MW696_15180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MW696_15185	COG0629	single-stranded DNA binding
MW696_15190	COG0360	Binds together with S18 to 16S ribosomal RNA
MW696_15195	COG0012	GTP binding
MW696_15200	COG4481	Protein conserved in bacteria
MW696_15205	COG3949	Membrane
MW696_15215	COG1475	DNA binding
MW696_15220	COG1192	Involved in chromosome partitioning
MW696_15225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MW696_15230	COG1595	DNA-templated transcription, initiation
MW696_15235	COG1475	DNA binding
MW696_15240	COG0357	Ribosomal RNA small subunit methyltransferase G
MW696_15245	COG0445	tRNA wobble uridine modification
MW696_15250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MW696_15255	COG1847	R3H domain protein
MW696_15260	COG0706	membrane insertase activity
MW696_15265	COG0594	ribonuclease P activity
MW696_15275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MW696_15280	COG0592	DNA-directed DNA polymerase activity
MW696_15285	COG2501	S4 domain
MW696_15290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MW696_15300	COG0187	DNA topoisomerase II activity
MW696_15305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MW696_15325	COG0516	GMP reductase activity
MW696_15325	COG0517	IMP dehydrogenase activity
MW696_15330	COG1686	Belongs to the peptidase S11 family
MW696_15335	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MW696_15340	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MW696_15345	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MW696_15350	COG1929	Belongs to the glycerate kinase type-1 family
MW696_15355	COG2610	gluconate transmembrane transporter activity
MW696_15360	COG3835	regulator
MW696_15365	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MW696_15375	COG1309	transcriptional regulator
MW696_15380	COG1428	Deoxynucleoside kinase
MW696_15385	COG1428	Deoxynucleoside kinase
MW696_15390	COG1388	LysM domain
MW696_15390	COG3858	chitin binding
MW696_15395	COG1335	isochorismatase
MW696_15400	COG0590	tRNA wobble adenosine to inosine editing
MW696_15410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MW696_15415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MW696_15420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MW696_15440	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MW696_15445	COG3853	Toxic anion resistance protein (TelA)
MW696_15450	COG1982	Orn Lys Arg decarboxylase major
MW696_15455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MW696_15460	COG3870	Protein conserved in bacteria
MW696_15465	COG1728	Protein conserved in bacteria
MW696_15470	COG0470	DNA polymerase III
MW696_15475	COG1774	PSP1 C-terminal conserved region
MW696_15480	COG4467	Involved in initiation control of chromosome replication
MW696_15485	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MW696_15490	COG2827	Endonuclease containing a URI domain
MW696_15495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MW696_15500	COG2002	toxin-antitoxin pair type II binding
MW696_15505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_15505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_15510	COG0084	hydrolase, TatD family'
MW696_15515	COG3583	domain protein
MW696_15515	COG3584	3D domain protein
MW696_15520	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MW696_15525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MW696_15535	COG4466	Protein conserved in bacteria
MW696_15545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MW696_15555	COG0251	oxidation-reduction process
MW696_15560	COG2088	sporulation resulting in formation of a cellular spore
MW696_15565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MW696_15570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MW696_15575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MW696_15580	COG0193	aminoacyl-tRNA hydrolase activity
MW696_15590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MW696_15595	COG2002	toxin-antitoxin pair type II binding
MW696_15600	COG2244	polysaccharide biosynthetic process
MW696_15605	COG3956	TIGRFAM MazG family protein
MW696_15610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MW696_15625	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MW696_15630	COG1098	S1 RNA binding domain
MW696_15645	COG2208	phosphoserine phosphatase activity
MW696_15650	COG2304	oxidoreductase activity
MW696_15655	COG0515	serine threonine protein kinase
MW696_15660	COG0037	tRNA processing
MW696_15665	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MW696_15670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MW696_15675	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MW696_15680	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MW696_15685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MW696_15690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MW696_15695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MW696_15700	COG0512	Glutamine amidotransferase of anthranilate synthase
MW696_15705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MW696_15710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MW696_15715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MW696_15720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MW696_15725	COG1396	sequence-specific DNA binding
MW696_15730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MW696_15735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MW696_15760	COG4463	regulation of RNA biosynthetic process
MW696_15765	COG3880	PFAM UvrB UvrC protein
MW696_15770	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MW696_15775	COG0542	response to heat
MW696_15780	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MW696_15785	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MW696_15790	COG4956	integral membrane protein (PIN domain superfamily)
MW696_15795	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MW696_15800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MW696_15805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MW696_15810	COG1045	serine acetyltransferase
MW696_15815	COG0215	cysteine-tRNA ligase activity
MW696_15825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MW696_15830	COG3688	RNA-binding protein containing a PIN domain
MW696_15840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MW696_15850	COG0250	Participates in transcription elongation, termination and antitermination
MW696_15855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MW696_15860	COG0081	regulation of translation
MW696_15865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MW696_15870	COG0222	ribosome binding
MW696_15875	COG2813	Specifically methylates the guanine in position
MW696_15880	COG0085	RNA polymerase activity
MW696_15885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MW696_15890	COG1358	cellular component organization or biogenesis
MW696_15895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MW696_15900	COG0049	tRNA binding
MW696_15905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MW696_15910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MW696_15920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MW696_15925	COG0088	Forms part of the polypeptide exit tunnel
MW696_15930	COG0089	rRNA binding
MW696_15935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MW696_15940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MW696_15945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MW696_15950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MW696_15955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MW696_15960	COG0255	Belongs to the universal ribosomal protein uL29 family
MW696_15965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MW696_15970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MW696_15975	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MW696_15980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MW696_15985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MW696_15990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MW696_15995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MW696_16000	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MW696_16005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MW696_16015	COG0200	Binds to the 23S rRNA
MW696_16020	COG0201	protein transport
MW696_16025	COG0563	adenylate kinase activity
MW696_16030	COG0024	Methionine aminopeptidase
MW696_16035	COG2163	COG2163 Ribosomal protein L14E L6E L27E
MW696_16040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MW696_16045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MW696_16050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MW696_16055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MW696_16060	COG0202	RNA polymerase activity
MW696_16065	COG0203	ribosomal protein L17
MW696_16070	COG1122	ATPase activity
MW696_16075	COG1122	ATPase activity
MW696_16080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MW696_16085	COG0101	tRNA pseudouridine synthase activity
MW696_16090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MW696_16095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MW696_16110	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_16115	COG0489	protein tyrosine kinase activity
MW696_16125	COG2194	sulfuric ester hydrolase activity
MW696_16130	COG0726	polysaccharide deacetylase
MW696_16145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MW696_16155	COG0385	Bile acid
MW696_16160	COG3876	Protein conserved in bacteria
MW696_16165	COG1472	Belongs to the glycosyl hydrolase 3 family
MW696_16170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MW696_16175	COG1263	PTS System
MW696_16175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_16180	COG1737	Transcriptional regulator
MW696_16185	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MW696_16190	COG1683	Conserved Protein
MW696_16215	COG1595	DNA-templated transcription, initiation
MW696_16220	COG5662	AntiSigma factor
MW696_16225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MW696_16230	COG4856	YbbR-like protein
MW696_16235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MW696_16240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MW696_16245	COG5646	InterPro IPR014922
MW696_16250	COG0640	Transcriptional regulator
MW696_16255	COG2814	Major facilitator Superfamily
MW696_16280	COG1725	Transcriptional regulator
MW696_16285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_16305	COG0596	Alpha beta hydrolase
MW696_16310	COG0745	RESPONSE REGULATOR receiver
MW696_16315	COG0642	Histidine kinase
MW696_16320	COG1132	(ABC) transporter
MW696_16335	COG1131	(ABC) transporter
MW696_16345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MW696_16365	COG2312	Erythromycin esterase
MW696_16385	COG1011	Hydrolase
MW696_16390	COG1113	amino acid transport
MW696_16430	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_16435	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_16440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MW696_16450	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_16480	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_16485	COG2315	Protein conserved in bacteria
MW696_16490	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_16495	COG3621	Patatin-like phospholipase
MW696_16525	COG1733	regulation of RNA biosynthetic process
MW696_16530	COG0596	Alpha beta hydrolase
MW696_16535	COG2211	Major facilitator Superfamily
MW696_16540	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_16540	COG3103	Sh3 type 3 domain protein
MW696_16540	COG4991	sh3 domain protein
MW696_16555	COG3764	Sortase (surface protein transpeptidase)
MW696_16565	COG2002	toxin-antitoxin pair type II binding
MW696_16580	COG0477	Major facilitator Superfamily
MW696_16585	COG1794	racemase activity, acting on amino acids and derivatives
MW696_16605	COG2226	methyltransferase
MW696_16610	COG0076	glutamate decarboxylase activity
MW696_16620	COG1846	Transcriptional regulator
MW696_16625	COG2409	Drug exporters of the RND superfamily
MW696_16625	COG1033	growth of symbiont in host cell
MW696_16635	COG0778	Nitroreductase
MW696_16640	COG1802	Transcriptional regulator
MW696_16645	COG0730	response to heat
MW696_16655	COG4682	membrane
MW696_16675	COG0697	spore germination
MW696_16680	COG1917	Cupin 2, conserved barrel domain protein
MW696_16680	COG2207	Transcriptional regulator
MW696_16700	COG0371	Dehydrogenase
MW696_16710	COG4257	antibiotic catabolic process
MW696_16725	COG3394	polysaccharide catabolic process
MW696_16730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_16730	COG1263	PTS System
MW696_16740	COG0789	Transcriptional regulator
MW696_16745	COG0531	amino acid
MW696_16750	COG2205	protein histidine kinase activity
MW696_16755	COG2304	oxidoreductase activity
MW696_16760	COG1115	amino acid carrier protein
MW696_16765	COG2066	Belongs to the glutaminase family
MW696_16770	COG4191	Histidine kinase
MW696_16775	COG0784	Response regulator, receiver
MW696_16785	COG3540	Alkaline phosphatase
MW696_16790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MW696_16795	COG0805	protein transport
MW696_16800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MW696_16805	COG1012	belongs to the aldehyde dehydrogenase family
MW696_16810	COG2271	Major facilitator Superfamily
MW696_16815	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_16820	COG2186	Transcriptional regulator
MW696_16825	COG2721	sulfolactate sulfo-lyase activity
MW696_16855	COG3173	Aminoglycoside phosphotransferase
MW696_16860	COG1846	Transcriptional regulator
MW696_16865	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_16885	COG0789	Transcriptional regulator
MW696_16895	COG0697	spore germination
MW696_16905	COG1714	RDD family
MW696_16910	COG3012	SEC-C Motif Domain Protein
MW696_16910	COG1405	negative regulation of cell septum assembly
MW696_16915	COG1131	(ABC) transporter
MW696_16940	COG0583	DNA-binding transcription factor activity
MW696_16945	COG1942	4-Oxalocrotonate Tautomerase
MW696_16950	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_16955	COG4106	trans-aconitate 2-methyltransferase activity
MW696_16975	COG0252	asparaginase activity
MW696_16980	COG0456	acetyltransferase
MW696_16990	COG1164	Oligoendopeptidase f
MW696_16995	COG2261	transglycosylase associated protein
MW696_17005	COG0247	lactate metabolic process
MW696_17010	COG0277	FAD linked oxidase domain protein
MW696_17015	COG3591	Belongs to the peptidase S1B family
MW696_17020	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_17030	COG1595	DNA-templated transcription, initiation
MW696_17045	COG3773	Cell wall hydrolase
MW696_17050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_17055	COG3883	PFAM NLP P60 protein
MW696_17055	COG0791	NLP P60 protein
MW696_17065	COG1131	(ABC) transporter
MW696_17070	COG1309	transcriptional regulator
MW696_17095	COG2310	stress, protein
MW696_17100	COG2310	stress, protein
MW696_17105	COG2310	stress, protein
MW696_17110	COG0861	Integral membrane protein TerC family
MW696_17125	COG1358	cellular component organization or biogenesis
MW696_17145	COG3853	Toxic anion resistance protein (TelA)
MW696_17150	COG0517	IMP dehydrogenase activity
MW696_17150	COG4175	Glycine betaine
MW696_17155	COG4176	ABC-type proline glycine betaine transport system permease component
MW696_17160	COG2113	Glycine betaine
MW696_17165	COG1473	amidohydrolase
MW696_17170	COG1288	antiporter activity
MW696_17175	COG2223	nitrite transmembrane transporter activity
MW696_17180	COG0477	Major facilitator Superfamily
MW696_17185	COG0039	L-malate dehydrogenase activity
MW696_17190	COG1620	l-lactate permease
MW696_17195	COG1280	lysine exporter protein (LysE YggA)
MW696_17200	COG1113	amino acid transport
MW696_17205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MW696_17210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MW696_17215	COG3541	Predicted nucleotidyltransferase
MW696_17220	COG0506	proline dehydrogenase activity
MW696_17225	COG1012	belongs to the aldehyde dehydrogenase family
MW696_17230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_17235	COG2508	Transcriptional regulator
MW696_17240	COG3689	TIGRFAM TIGR03943 family protein
MW696_17245	COG0701	Predicted permease
MW696_17250	COG3458	cephalosporin-C deacetylase activity
MW696_17275	COG0765	amino acid transport
MW696_17280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_17295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MW696_17300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_17305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_17310	COG1120	ATPase activity
MW696_17315	COG3842	ATPase activity
MW696_17320	COG2723	6-phospho-beta-galactosidase activity
MW696_17345	COG5444	nuclease activity
MW696_17365	COG3842	ATPase activity
MW696_17370	COG1176	ABC-type spermidine putrescine transport system, permease component I
MW696_17380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_17390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_17395	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MW696_17400	COG0697	spore germination
MW696_17405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_17415	COG2819	hydrolase of the alpha beta superfamily
MW696_17420	COG2207	Transcriptional regulator
MW696_17420	COG3708	Transcriptional regulator
MW696_17430	COG2364	Membrane
MW696_17455	COG1126	abc transporter atp-binding protein
MW696_17460	COG0765	amino acid transport
MW696_17465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_17470	COG3829	transcription factor binding
MW696_17475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MW696_17480	COG0833	amino acid
MW696_17485	COG0010	Belongs to the arginase family
MW696_17490	COG2364	Membrane
MW696_17495	COG1846	Transcriptional regulator
MW696_17500	COG0456	acetyltransferase
MW696_17505	COG2808	Putative FMN-binding domain
MW696_17510	COG0583	DNA-binding transcription factor activity
MW696_17515	COG0163	prenyltransferase activity
MW696_17520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MW696_17555	COG5444	nuclease activity
MW696_17575	COG2972	Histidine kinase
MW696_17580	COG2197	response regulator
MW696_17585	COG4213	ABC transporter substrate-binding protein
MW696_17595	COG4214	carbohydrate transport
MW696_17600	COG2271	Major facilitator Superfamily
MW696_17605	COG0456	acetyltransferase
MW696_17605	COG1846	Transcriptional regulator
MW696_17610	COG1874	Beta-galactosidase
MW696_17615	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
MW696_17625	COG3104	oligopeptide transport
MW696_17630	COG5434	Belongs to the glycosyl hydrolase 28 family
MW696_17640	COG0697	spore germination
MW696_17650	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MW696_17655	COG0789	Transcriptional regulator
MW696_17660	COG1136	(ABC) transporter
MW696_17665	COG0577	efflux transmembrane transporter activity
MW696_17670	COG0745	RESPONSE REGULATOR receiver
MW696_17675	COG3850	Histidine kinase
MW696_17675	COG5002	protein histidine kinase activity
MW696_17680	COG5278	phosphoserine phosphatase activity
MW696_17680	COG0840	transmembrane signaling receptor activity
MW696_17685	COG0527	aspartate kinase activity
MW696_17690	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_17695	COG4605	iron ion homeostasis
MW696_17700	COG4604	ABC transporter, ATP-binding protein
MW696_17705	COG4607	ABC-type enterochelin transport system periplasmic component
MW696_17710	COG2814	Major facilitator Superfamily
MW696_17715	COG1309	transcriptional regulator
MW696_17725	COG0778	Nitroreductase
MW696_17730	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MW696_17735	COG0640	Transcriptional regulator
MW696_17740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_17745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MW696_17750	COG0531	amino acid
MW696_17755	COG1012	belongs to the aldehyde dehydrogenase family
MW696_17760	COG4221	oxidoreductase activity
MW696_17765	COG4549	nuclear export factor GLE1
MW696_17770	COG1276	copper resistance
MW696_17770	COG2372	response to copper ion
MW696_17775	COG1349	DNA-binding transcription factor activity
MW696_17780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MW696_17785	COG0243	molybdopterin cofactor binding
MW696_17790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MW696_17795	COG2146	nitrite reductase [NAD(P)H] activity
MW696_17800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MW696_17800	COG1587	Uroporphyrinogen-III synthase
MW696_17805	COG0789	Transcriptional regulator
MW696_17820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MW696_17830	COG0561	phosphatase activity
MW696_17835	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MW696_17840	COG1914	H( )-stimulated, divalent metal cation uptake system
MW696_17845	COG4336	lyase activity
MW696_17850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MW696_17855	COG1984	allophanate hydrolase subunit 2
MW696_17860	COG1414	Transcriptional regulator
MW696_17865	COG2755	lipolytic protein G-D-S-L family
MW696_17870	COG2213	PTS system mannitol-specific
MW696_17875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_17880	COG0246	Mannitol dehydrogenase
MW696_17885	COG3711	transcriptional antiterminator
MW696_17890	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_17895	COG1917	Cupin 2, conserved barrel domain protein
MW696_17900	COG3871	stress protein (general stress protein 26)
MW696_17915	COG2814	Major facilitator Superfamily
MW696_17925	COG1522	sequence-specific DNA binding
MW696_17930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MW696_17930	COG0551	DNA topoisomerase type I activity
MW696_17940	COG0287	Prephenate dehydrogenase
MW696_17945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MW696_17945	COG0512	Glutamine amidotransferase of anthranilate synthase
MW696_17950	COG1605	Chorismate mutase
MW696_17955	COG0531	amino acid
MW696_17960	COG0028	Belongs to the TPP enzyme family
MW696_17970	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_17980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_17985	COG1914	H( )-stimulated, divalent metal cation uptake system
MW696_17990	COG2261	transglycosylase associated protein
MW696_17995	COG1027	Aspartate ammonia-lyase
MW696_18000	COG1819	glycosyl
MW696_18005	COG4876	unkown
MW696_18010	COG2217	Heavy metal translocating P-type atpase
MW696_18025	COG0662	Cupin 2, conserved barrel domain protein
MW696_18035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MW696_18040	COG3290	protein histidine kinase activity
MW696_18045	COG4565	transcriptional regulatory protein
MW696_18050	COG1301	dicarboxylic acid transport
MW696_18055	COG0628	permease
MW696_18065	COG1131	(ABC) transporter
MW696_18070	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MW696_18080	COG1960	acyl-CoA dehydrogenase activity
MW696_18095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_18100	COG1181	Belongs to the D-alanine--D-alanine ligase family
MW696_18105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MW696_18115	COG0513	Belongs to the DEAD box helicase family
MW696_18120	COG3402	PFAM membrane-flanked domain
MW696_18125	COG3428	Bacterial PH domain
MW696_18130	COG0705	Rhomboid family
MW696_18135	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MW696_18140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MW696_18145	COG0864	Transcriptional regulator
MW696_18150	COG2337	Toxic component of a toxin-antitoxin (TA) module
MW696_18155	COG1366	Belongs to the anti-sigma-factor antagonist family
MW696_18160	COG1366	Belongs to the anti-sigma-factor antagonist family
MW696_18165	COG2172	sigma factor antagonist activity
MW696_18170	COG2208	phosphoserine phosphatase activity
MW696_18185	COG1191	sigma factor activity
MW696_18190	COG2208	phosphoserine phosphatase activity
MW696_18195	COG2183	response to ionizing radiation
MW696_18205	COG3091	SprT-like family
MW696_18245	COG1476	TRANSCRIPTIONal
MW696_18255	COG3239	Fatty acid desaturase
MW696_18260	COG1278	Cold shock
MW696_18265	COG0582	viral genome integration into host DNA
MW696_18275	COG0726	polysaccharide deacetylase
MW696_18295	COG0457	Tetratricopeptide repeat
MW696_18300	COG0640	Transcriptional regulator
MW696_18310	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MW696_18320	COG1733	regulation of RNA biosynthetic process
MW696_18325	COG0697	spore germination
MW696_18330	COG2207	Transcriptional regulator
MW696_18330	COG1917	Cupin 2, conserved barrel domain protein
MW696_18335	COG0697	spore germination
MW696_18340	COG2814	Major facilitator Superfamily
MW696_18345	COG1309	transcriptional regulator
MW696_18350	COG0110	maltose O-acetyltransferase activity
MW696_18355	COG2814	Major facilitator Superfamily
MW696_18360	COG0789	Transcriptional regulator
MW696_18360	COG4978	Transcriptional regulator
MW696_18365	COG1114	Component of the transport system for branched-chain amino acids
MW696_18370	COG3621	Patatin-like phospholipase
MW696_18375	COG1733	regulation of RNA biosynthetic process
MW696_18380	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_18385	COG1113	amino acid transport
MW696_18390	COG1216	Glycosyl transferase, family 2
MW696_18400	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MW696_18415	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_18420	COG0778	Nitroreductase
MW696_18430	COG0596	Alpha beta hydrolase
MW696_18435	COG5566	PFAM Mor transcription activator
MW696_18440	COG1595	DNA-templated transcription, initiation
MW696_18450	COG2755	lipolytic protein G-D-S-L family
MW696_18450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MW696_18455	COG0494	nUDIX hydrolase
MW696_18460	COG2814	Major facilitator Superfamily
MW696_18465	COG1979	alcohol dehydrogenase
MW696_18470	COG0745	RESPONSE REGULATOR receiver
MW696_18470	COG2972	Histidine kinase
MW696_18480	COG3279	Response regulator of the LytR AlgR family
MW696_18485	COG1388	LysM domain
MW696_18485	COG4932	domain protein
MW696_18490	COG3764	Sortase (surface protein transpeptidase)
MW696_18495	COG2851	Citrate transporter
MW696_18500	COG3181	Tripartite tricarboxylate transporter family receptor
MW696_18505	COG4565	transcriptional regulatory protein
MW696_18515	COG2814	Major facilitator Superfamily
MW696_18545	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MW696_18550	COG0802	atpase or kinase
MW696_18555	COG1214	PFAM Peptidase M22, glycoprotease
MW696_18560	COG0456	acetyltransferase
MW696_18565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MW696_18570	COG0488	(ABC) transporter
MW696_18575	COG0315	cyclic pyranopterin monophosphate synthase activity
MW696_18580	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MW696_18585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MW696_18590	COG0805	protein transport
MW696_18600	COG1266	CAAX protease self-immunity
MW696_18605	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MW696_18610	COG0459	protein refolding
MW696_18635	COG0756	dUTP diphosphatase activity
MW696_18675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MW696_18690	COG2323	membrane
MW696_18695	COG2135	peptidase activity
MW696_18700	COG0346	lactoylglutathione lyase activity
MW696_18705	COG0531	amino acid
MW696_18740	COG3189	MarR family transcriptional regulator
MW696_18745	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MW696_18750	COG2272	Belongs to the type-B carboxylesterase lipase family
MW696_18755	COG2814	Major facilitator Superfamily
MW696_18765	COG1378	Sugar-specific transcriptional regulator TrmB
MW696_18770	COG1280	lysine exporter protein (LysE YggA)
MW696_18775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MW696_18805	COG0726	polysaccharide deacetylase
MW696_18815	COG1609	Transcriptional regulator
MW696_18825	COG2182	Extracellular solute-binding protein
MW696_18830	COG1175	transmembrane transport
MW696_18835	COG3833	ABC-type maltose transport systems, permease component
MW696_18840	COG5521	maltodextrose utilization protein MalA
MW696_18845	COG1554	hydrolase, family 65, central catalytic
MW696_18850	COG0366	Alpha amylase catalytic
MW696_18855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MW696_18880	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MW696_18885	COG0823	Involved in the tonB-independent uptake of proteins
MW696_18905	COG0702	epimerase
MW696_18915	COG2132	Multicopper oxidase
MW696_18925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MW696_18930	COG0714	Associated with various cellular activities
MW696_18935	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MW696_18940	COG1305	Transglutaminase-like
MW696_18945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MW696_18945	COG0519	Catalyzes the synthesis of GMP from XMP
MW696_18950	COG2252	PERMEase
MW696_18965	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MW696_18975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MW696_18980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MW696_18985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MW696_18990	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MW696_18995	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MW696_19000	COG0047	phosphoribosylformylglycinamidine synthase activity
MW696_19005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MW696_19010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MW696_19015	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MW696_19020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MW696_19025	COG0138	bifunctional purine biosynthesis protein purh
MW696_19030	COG0151	Belongs to the GarS family
MW696_19050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MW696_19055	COG1470	cell adhesion involved in biofilm formation
MW696_19060	COG4496	protein, YerC YecD
MW696_19065	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MW696_19070	COG0210	DNA helicase
MW696_19075	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MW696_19080	COG4851	CamS sex pheromone cAM373 precursor
MW696_19085	COG1285	pathogenesis
MW696_19095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_19100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MW696_19105	COG0154	amidase activity
MW696_19110	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MW696_19115	COG4124	Belongs to the glycosyl hydrolase 26 family
MW696_19120	COG1063	alcohol dehydrogenase
MW696_19125	COG1309	transcriptional regulator
MW696_19130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MW696_19135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_19140	COG1957	nucleoside hydrolase
MW696_19145	COG1597	lipid kinase activity
MW696_19150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MW696_19170	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MW696_19175	COG3711	transcriptional antiterminator
MW696_19180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MW696_19185	COG0457	Tetratricopeptide repeat
MW696_19190	COG0457	Tetratricopeptide repeat
MW696_19215	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_19220	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MW696_19220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MW696_19225	COG3586	endonuclease activity
MW696_19230	COG0697	spore germination
MW696_19235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_19240	COG0697	spore germination
MW696_19245	COG0217	transcriptional regulatory protein
MW696_19260	COG0471	metal ion transport
MW696_19265	COG0281	malic enzyme
MW696_19270	COG0583	DNA-binding transcription factor activity
MW696_19275	COG1012	belongs to the aldehyde dehydrogenase family
MW696_19280	COG0840	transmembrane signaling receptor activity
MW696_19285	COG0109	protoheme IX farnesyltransferase activity
MW696_19290	COG1309	transcriptional regulator
MW696_19295	COG0471	metal ion transport
MW696_19300	COG0488	(ABC) transporter
MW696_19305	COG0640	Transcriptional regulator
MW696_19310	COG2814	Major facilitator Superfamily
MW696_19315	COG1469	GTP cyclohydrolase I activity
MW696_19320	COG0523	cobalamin synthesis protein
MW696_19325	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MW696_19330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MW696_19335	COG0156	8-amino-7-oxononanoate synthase activity
MW696_19340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MW696_19345	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MW696_19350	COG2124	cytochrome p450
MW696_19355	COG0789	Transcriptional regulator
MW696_19360	COG2814	Major facilitator Superfamily
MW696_19365	COG0488	(ABC) transporter
MW696_19370	COG0513	Belongs to the DEAD box helicase family
MW696_19385	COG0471	metal ion transport
MW696_19395	COG1136	(ABC) transporter
MW696_19415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_19425	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MW696_19430	COG3858	chitin binding
MW696_19440	COG5658	integral membrane protein
MW696_19445	COG0640	Transcriptional regulator
MW696_19450	COG1254	Belongs to the acylphosphatase family
MW696_19455	COG2258	MOSC domain
MW696_19470	COG0024	Methionine aminopeptidase
MW696_19475	COG1368	sulfuric ester hydrolase activity
MW696_19485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_19485	COG1263	PTS System
MW696_19490	COG0366	Alpha amylase catalytic
MW696_19495	COG2188	Transcriptional regulator
MW696_19510	COG0463	Glycosyl transferase, family 2
MW696_19515	COG0457	Tetratricopeptide repeat
MW696_19515	COG0463	Glycosyl transferase, family 2
MW696_19520	COG0438	transferase activity, transferring glycosyl groups
MW696_19535	COG0673	inositol 2-dehydrogenase activity
MW696_19550	COG2076	Multidrug Resistance protein
MW696_19555	COG1309	transcriptional regulator
MW696_19560	COG0657	acetylesterase activity
MW696_19565	COG1733	regulation of RNA biosynthetic process
MW696_19570	COG0778	Nitroreductase
MW696_19585	COG0737	Belongs to the 5'-nucleotidase family
MW696_19590	COG0693	protein deglycase activity
MW696_19595	COG4840	Belongs to the UPF0435 family
MW696_19600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MW696_19605	COG4980	gas vesicle protein
MW696_19610	COG1295	ribonuclease BN
MW696_19615	COG0477	Major facilitator Superfamily
MW696_19625	COG0387	Pfam Sodium calcium exchanger
MW696_19635	COG0535	radical SAM domain protein
MW696_19645	COG0726	polysaccharide deacetylase
MW696_19650	COG0371	Dehydrogenase
MW696_19665	COG0598	Magnesium transport protein CorA
MW696_19670	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MW696_19675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MW696_19680	COG4637	Psort location Cytoplasmic, score
MW696_19700	COG1819	glycosyl
MW696_19710	COG0477	Major facilitator Superfamily
MW696_19715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_19715	COG1263	PTS System
MW696_19720	COG3711	transcriptional antiterminator
MW696_19730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MW696_19735	COG0022	dehydrogenase e1 component
MW696_19740	COG0508	dehydrogenase complex catalyzes the overall conversion of
MW696_19745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MW696_19750	COG3284	Transcriptional regulator
MW696_19755	COG1742	UPF0060 membrane protein
MW696_19760	COG1486	melibiose metabolic process
MW696_19765	COG1737	Transcriptional regulator
MW696_19770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_19770	COG1263	PTS System
MW696_19780	COG1733	regulation of RNA biosynthetic process
MW696_19785	COG2259	Doxx family
MW696_19790	COG2514	catechol 2,3-dioxygenase activity
MW696_19800	COG3507	Belongs to the glycosyl hydrolase 43 family
MW696_19805	COG2207	Transcriptional regulator
MW696_19805	COG1917	Cupin 2, conserved barrel domain protein
MW696_19810	COG1653	transport
MW696_19815	COG1653	transport
MW696_19820	COG1309	transcriptional regulator
MW696_19825	COG2814	Major facilitator Superfamily
MW696_19830	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_19835	COG1051	belongs to the nudix hydrolase family
MW696_19845	COG0392	lysyltransferase activity
MW696_19845	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MW696_19850	COG0384	phenazine biosynthesis protein PhzF
MW696_19855	COG0778	Nitroreductase
MW696_19880	COG2137	regulation of response to DNA damage stimulus
MW696_19905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MW696_19910	COG0463	Glycosyl transferase, family 2
MW696_19920	COG4485	Bacterial membrane protein, YfhO
MW696_19925	COG1988	membrane-bound metal-dependent
MW696_19930	COG1194	a g-specific adenine glycosylase
MW696_19940	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_19955	COG3557	Belongs to the UPF0374 family
MW696_19960	COG1132	(ABC) transporter
MW696_19965	COG0444	Belongs to the ABC transporter superfamily
MW696_19970	COG4608	Belongs to the ABC transporter superfamily
MW696_19975	COG0747	negative chemotaxis
MW696_19980	COG0601	transmembrane transport
MW696_19985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MW696_19990	COG4129	membrane
MW696_19995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MW696_20000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MW696_20005	COG0735	belongs to the Fur family
MW696_20080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MW696_20100	COG0710	3-dehydroquinate dehydratase activity
MW696_20105	COG4326	sporulation control protein
MW696_20110	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MW696_20115	COG1116	anion transmembrane transporter activity
MW696_20120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MW696_20125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MW696_20130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_20140	COG1476	TRANSCRIPTIONal
MW696_20150	COG1122	ATPase activity
MW696_20170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MW696_20180	COG3382	B3 4 domain protein
MW696_20185	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MW696_20195	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MW696_20200	COG0789	Transcriptional regulator
MW696_20205	COG1664	Polymer-forming cytoskeletal
MW696_20215	COG2766	serine protein kinase
MW696_20220	COG2718	Belongs to the UPF0229 family
MW696_20225	COG1566	PFAM secretion protein HlyD family protein
MW696_20230	COG2814	Major facilitator Superfamily
MW696_20235	COG0655	NAD(P)H dehydrogenase (quinone) activity
MW696_20250	COG1725	Transcriptional regulator
MW696_20255	COG1131	(ABC) transporter
MW696_20260	COG1131	(ABC) transporter
MW696_20265	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MW696_20270	COG1278	Cold shock
MW696_20275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MW696_20280	COG2011	ABC-type metal ion transport system permease component
MW696_20285	COG1464	Belongs to the NlpA lipoprotein family
MW696_20290	COG1823	symporter activity
MW696_20315	COG5577	PFAM Coat F domain
MW696_20320	COG5002	protein histidine kinase activity
MW696_20325	COG4085	toxin activity
MW696_20325	COG0737	Belongs to the 5'-nucleotidase family
MW696_20325	COG1525	nuclease
MW696_20330	COG3764	Sortase (surface protein transpeptidase)
MW696_20335	COG0517	IMP dehydrogenase activity
MW696_20335	COG1125	glycine betaine transport
MW696_20340	COG1174	glycine betaine transport
MW696_20345	COG1732	Glycine betaine
MW696_20350	COG1174	glycine betaine transport
MW696_20355	COG0564	pseudouridine synthase activity
MW696_20365	COG0517	IMP dehydrogenase activity
MW696_20370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MW696_20375	COG3153	acetyltransferase
MW696_20375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MW696_20380	COG0488	(ABC) transporter
MW696_20395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MW696_20400	COG0604	alcohol dehydrogenase
MW696_20405	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MW696_20410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MW696_20415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MW696_20420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MW696_20425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MW696_20450	COG4585	Histidine kinase
MW696_20450	COG2203	Gaf domain
MW696_20455	COG2197	response regulator
MW696_20460	COG0431	NADPH-dependent FMN reductase
MW696_20475	COG1959	2 iron, 2 sulfur cluster binding
MW696_20480	COG1017	nitric oxide dioxygenase activity
MW696_20480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MW696_20485	COG2719	SpoVR family
MW696_20490	COG1785	Belongs to the alkaline phosphatase family
MW696_20500	COG1388	LysM domain
MW696_20500	COG0791	NLP P60 protein
MW696_20505	COG0583	DNA-binding transcription factor activity
MW696_20510	COG0372	Belongs to the citrate synthase family
MW696_20515	COG1846	Transcriptional regulator
MW696_20520	COG0531	amino acid
MW696_20525	COG0733	neurotransmitter:sodium symporter activity
MW696_20535	COG3708	Transcriptional regulator
MW696_20535	COG2207	Transcriptional regulator
MW696_20540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_20560	COG1595	DNA-templated transcription, initiation
MW696_20565	COG0204	Acyl-transferase
MW696_20580	COG1253	flavin adenine dinucleotide binding
MW696_20585	COG0789	Transcriptional regulator
MW696_20590	COG1253	flavin adenine dinucleotide binding
MW696_20610	COG3739	integral membrane protein
MW696_20615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MW696_20620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MW696_20625	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_20635	COG0668	transmembrane transport
MW696_20640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MW696_20645	COG0454	-acetyltransferase
MW696_20650	COG0726	polysaccharide deacetylase
MW696_20660	COG1757	Na H antiporter
MW696_20665	COG2017	converts alpha-aldose to the beta-anomer
MW696_20690	COG0589	response to stress
MW696_20695	COG1132	(ABC) transporter
MW696_20700	COG1132	(ABC) transporter
MW696_20705	COG0702	epimerase
MW696_20730	COG3842	ATPase activity
MW696_20735	COG2508	Transcriptional regulator
MW696_20745	COG0189	ligase activity
MW696_20750	COG0189	ligase activity
MW696_20755	COG4399	Belongs to the UPF0754 family
MW696_20760	COG3679	Belongs to the UPF0342 family
MW696_20765	COG0561	phosphatase activity
MW696_20780	COG0475	glutathione-regulated potassium exporter activity
MW696_20785	COG0490	domain, Protein
MW696_20795	COG1024	Enoyl-CoA hydratase
MW696_20800	COG0457	Tetratricopeptide repeat
MW696_20815	COG4152	abc transporter atp-binding protein
MW696_20820	COG1668	transmembrane transport
MW696_20825	COG0420	3'-5' exonuclease activity
MW696_20830	COG4717	serine-type aminopeptidase activity
MW696_20835	COG3481	metal-dependent phosphohydrolase, HD sub domain
MW696_20845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MW696_20875	COG1846	Transcriptional regulator
MW696_20880	COG4980	gas vesicle protein
MW696_20895	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MW696_20900	COG0537	adenosine 5'-monophosphoramidase activity
MW696_20905	COG1131	(ABC) transporter
MW696_20910	COG4473	ABC transporter
MW696_20920	COG1473	amidohydrolase
MW696_20930	COG2329	Antibiotic biosynthesis monooxygenase
MW696_20935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MW696_20940	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MW696_20945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MW696_20950	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MW696_20955	COG1309	transcriptional regulator
MW696_20960	COG1511	domain protein
MW696_20965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MW696_20970	COG1363	Peptidase, m42
MW696_20980	COG1301	dicarboxylic acid transport
MW696_20990	COG1234	tRNA 3'-trailer cleavage
MW696_20995	COG0095	Lipoate-protein ligase
MW696_21000	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_21010	COG1396	sequence-specific DNA binding
MW696_21025	COG0501	Belongs to the peptidase M48B family
MW696_21035	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MW696_21040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_21045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_21050	COG0406	alpha-ribazole phosphatase activity
MW696_21055	COG0840	transmembrane signaling receptor activity
MW696_21060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MW696_21060	COG0723	plastoquinol--plastocyanin reductase activity
MW696_21065	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_21075	COG4903	ComK protein
MW696_21085	COG0398	Pfam SNARE associated Golgi protein
MW696_21090	COG0681	Belongs to the peptidase S26 family
MW696_21110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MW696_21120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MW696_21125	COG3257	ureidoglycine aminohydrolase activity
MW696_21130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MW696_21135	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MW696_21140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MW696_21145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MW696_21155	COG0549	Belongs to the carbamate kinase family
MW696_21165	COG0457	Tetratricopeptide repeat
MW696_21175	COG3180	Ammonia monooxygenase
MW696_21190	COG3546	catalase activity
MW696_21195	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_21200	COG2720	vancomycin resistance protein
MW696_21205	COG5002	protein histidine kinase activity
MW696_21210	COG0745	RESPONSE REGULATOR receiver
MW696_21215	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MW696_21220	COG0725	ABC transporter, periplasmic molybdate-binding protein
MW696_21225	COG4149	molybdate abc transporter
MW696_21230	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MW696_21235	COG1074	ATP-dependent DNA helicase activity
MW696_21240	COG0420	3'-5' exonuclease activity
MW696_21245	COG0419	ATPase involved in DNA repair
MW696_21290	COG5337	Spore coat protein CotH
MW696_21300	COG0179	Fumarylacetoacetate (FAA) hydrolase
MW696_21320	COG0367	asparagine synthase
MW696_21325	COG0534	Mate efflux family protein
MW696_21330	COG1917	Cupin 2, conserved barrel domain protein
MW696_21330	COG2207	Transcriptional regulator
MW696_21360	COG0697	spore germination
MW696_21365	COG1279	arginine transmembrane transporter activity
MW696_21370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_21380	COG0076	glutamate decarboxylase activity
MW696_21405	COG2153	protein acetylation
MW696_21410	COG0646	methionine synthase
MW696_21410	COG1410	methionine synthase
MW696_21415	COG0646	methionine synthase
MW696_21415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MW696_21420	COG1666	GTP binding
MW696_21425	COG2996	Protein conserved in bacteria
MW696_21440	COG1307	EDD domain protein, DegV family
MW696_21445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_21455	COG0516	GMP reductase activity
MW696_21470	COG0561	phosphatase activity
MW696_21475	COG1073	alpha beta
MW696_21480	COG2151	metal-sulfur cluster biosynthetic enzyme
MW696_21485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MW696_21490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MW696_21495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MW696_21500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MW696_21505	COG0505	Belongs to the CarA family
MW696_21510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MW696_21515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MW696_21530	COG2267	carboxylic ester hydrolase activity
MW696_21540	COG1744	ABC transporter substrate-binding protein PnrA-like
MW696_21555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MW696_21560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MW696_21565	COG5504	Zn-dependent protease
MW696_21570	COG0444	Belongs to the ABC transporter superfamily
MW696_21575	COG4608	Belongs to the ABC transporter superfamily
MW696_21585	COG0601	transmembrane transport
MW696_21590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MW696_21600	COG0180	Tryptophanyl-tRNA synthetase
MW696_21605	COG4166	transmembrane transport
MW696_21610	COG0601	transmembrane transport
MW696_21615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MW696_21620	COG0444	Belongs to the ABC transporter superfamily
MW696_21625	COG4608	Belongs to the ABC transporter superfamily
MW696_21630	COG0456	acetyltransferase
MW696_21635	COG1393	Belongs to the ArsC family
MW696_21640	COG0861	Integral membrane protein TerC family
MW696_21650	COG4862	establishment of competence for transformation
MW696_21655	COG4469	Competence protein
MW696_21660	COG1164	Oligoendopeptidase f
MW696_21670	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MW696_21675	COG2346	COG2346, Truncated hemoglobins
MW696_21680	COG0741	lytic transglycosylase activity
MW696_21685	COG4116	CYTH
MW696_21695	COG2357	RelA SpoT domain protein
MW696_21700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MW696_21705	COG0564	pseudouridine synthase activity
MW696_21710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MW696_21715	COG0475	glutathione-regulated potassium exporter activity
MW696_21715	COG0569	domain protein
MW696_21720	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MW696_21725	COG0352	thiamine-phosphate diphosphorylase activity
MW696_21735	COG2104	thiamine diphosphate biosynthetic process
MW696_21740	COG2022	thiamine diphosphate biosynthetic process
MW696_21745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MW696_21750	COG0351	phosphomethylpyrimidine kinase
MW696_21755	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MW696_21810	COG0210	DNA helicase
MW696_21820	COG0586	Pfam SNARE associated Golgi protein
MW696_21825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MW696_21835	COG2246	polysaccharide biosynthetic process
MW696_21840	COG2153	protein acetylation
MW696_21845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MW696_21850	COG2382	esterase
MW696_21855	COG0626	cystathionine gamma-synthase activity
MW696_21860	COG0626	cystathionine gamma-synthase activity
MW696_21885	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MW696_21895	COG3591	Belongs to the peptidase S1B family
MW696_21920	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_21925	COG0346	lactoylglutathione lyase activity
MW696_21945	COG2267	carboxylic ester hydrolase activity
MW696_21965	COG0531	amino acid
MW696_21975	COG0583	DNA-binding transcription factor activity
MW696_21980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MW696_21985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MW696_21990	COG0583	DNA-binding transcription factor activity
MW696_21995	COG0697	spore germination
MW696_22000	COG0346	lactoylglutathione lyase activity
MW696_22010	COG3584	3D domain protein
MW696_22010	COG1388	LysM domain
MW696_22020	COG5434	Belongs to the glycosyl hydrolase 28 family
MW696_22025	COG2814	Major facilitator Superfamily
MW696_22030	COG1309	transcriptional regulator
MW696_22065	COG5444	nuclease activity
MW696_22070	COG0457	Tetratricopeptide repeat
MW696_22095	COG5444	nuclease activity
MW696_22110	COG4195	phage-related replication protein
MW696_22115	COG2856	Zn peptidase
MW696_22120	COG1396	sequence-specific DNA binding
MW696_22135	COG1522	sequence-specific DNA binding
MW696_22140	COG1484	DNA-dependent DNA replication
MW696_22160	COG1595	DNA-templated transcription, initiation
MW696_22170	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_22190	COG1802	Transcriptional regulator
MW696_22195	COG1063	alcohol dehydrogenase
MW696_22200	COG1312	Catalyzes the dehydration of D-mannonate
MW696_22205	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_22210	COG1063	alcohol dehydrogenase
MW696_22215	COG2271	Major facilitator Superfamily