locus-tag	class	description
EQZ20_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EQZ20_00010	COG0592	DNA-directed DNA polymerase activity
EQZ20_00015	COG2501	S4 domain
EQZ20_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EQZ20_00030	COG0187	DNA topoisomerase II activity
EQZ20_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQZ20_00070	COG0516	GMP reductase activity
EQZ20_00070	COG0517	IMP dehydrogenase activity
EQZ20_00075	COG1686	Belongs to the peptidase S11 family
EQZ20_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EQZ20_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EQZ20_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EQZ20_00095	COG1929	Belongs to the glycerate kinase type-1 family
EQZ20_00100	COG2610	gluconate transmembrane transporter activity
EQZ20_00105	COG3835	regulator
EQZ20_00120	COG1428	Deoxynucleoside kinase
EQZ20_00125	COG1428	Deoxynucleoside kinase
EQZ20_00130	COG1388	LysM domain
EQZ20_00130	COG3858	chitin binding
EQZ20_00135	COG1335	isochorismatase
EQZ20_00140	COG0590	tRNA wobble adenosine to inosine editing
EQZ20_00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EQZ20_00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EQZ20_00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EQZ20_00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EQZ20_00210	COG3853	Toxic anion resistance protein (TelA)
EQZ20_00215	COG1982	Orn Lys Arg decarboxylase major
EQZ20_00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EQZ20_00225	COG3870	Protein conserved in bacteria
EQZ20_00230	COG1728	Protein conserved in bacteria
EQZ20_00235	COG0470	DNA polymerase III
EQZ20_00240	COG1774	PSP1 C-terminal conserved region
EQZ20_00245	COG4467	Involved in initiation control of chromosome replication
EQZ20_00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EQZ20_00255	COG2827	Endonuclease containing a URI domain
EQZ20_00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EQZ20_00265	COG2002	toxin-antitoxin pair type II binding
EQZ20_00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ20_00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ20_00275	COG0084	hydrolase, TatD family'
EQZ20_00280	COG3584	3D domain protein
EQZ20_00280	COG3583	domain protein
EQZ20_00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQZ20_00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EQZ20_00305	COG4466	Protein conserved in bacteria
EQZ20_00315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EQZ20_00320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQZ20_00325	COG0251	oxidation-reduction process
EQZ20_00330	COG2088	sporulation resulting in formation of a cellular spore
EQZ20_00335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EQZ20_00340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQZ20_00345	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EQZ20_00350	COG0193	aminoacyl-tRNA hydrolase activity
EQZ20_00360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EQZ20_00365	COG2002	toxin-antitoxin pair type II binding
EQZ20_00370	COG2244	polysaccharide biosynthetic process
EQZ20_00375	COG3956	TIGRFAM MazG family protein
EQZ20_00380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EQZ20_00395	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EQZ20_00400	COG1098	S1 RNA binding domain
EQZ20_00415	COG2208	phosphoserine phosphatase activity
EQZ20_00420	COG2304	oxidoreductase activity
EQZ20_00425	COG0515	serine threonine protein kinase
EQZ20_00430	COG0037	tRNA processing
EQZ20_00440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EQZ20_00445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EQZ20_00450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EQZ20_00455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQZ20_00460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQZ20_00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQZ20_00470	COG0512	Glutamine amidotransferase of anthranilate synthase
EQZ20_00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQZ20_00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EQZ20_00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EQZ20_00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQZ20_00495	COG1396	sequence-specific DNA binding
EQZ20_00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EQZ20_00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EQZ20_00585	COG4463	regulation of RNA biosynthetic process
EQZ20_00590	COG3880	PFAM UvrB UvrC protein
EQZ20_00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EQZ20_00600	COG0542	response to heat
EQZ20_00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EQZ20_00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EQZ20_00615	COG4956	integral membrane protein (PIN domain superfamily)
EQZ20_00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EQZ20_00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EQZ20_00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EQZ20_00635	COG1045	serine acetyltransferase
EQZ20_00640	COG0215	cysteine-tRNA ligase activity
EQZ20_00645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EQZ20_00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQZ20_00655	COG3688	RNA-binding protein containing a PIN domain
EQZ20_00665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQZ20_00675	COG0250	Participates in transcription elongation, termination and antitermination
EQZ20_00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EQZ20_00685	COG0081	regulation of translation
EQZ20_00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EQZ20_00695	COG0222	ribosome binding
EQZ20_00700	COG2813	Specifically methylates the guanine in position
EQZ20_00705	COG0085	RNA polymerase activity
EQZ20_00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EQZ20_00715	COG1358	cellular component organization or biogenesis
EQZ20_00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EQZ20_00725	COG0049	tRNA binding
EQZ20_00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EQZ20_00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EQZ20_00740	COG0051	transcription antitermination factor activity, RNA binding
EQZ20_00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EQZ20_00750	COG0088	Forms part of the polypeptide exit tunnel
EQZ20_00755	COG0089	rRNA binding
EQZ20_00760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EQZ20_00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EQZ20_00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EQZ20_00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EQZ20_00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EQZ20_00785	COG0255	Belongs to the universal ribosomal protein uL29 family
EQZ20_00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EQZ20_00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EQZ20_00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EQZ20_00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EQZ20_00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQZ20_00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EQZ20_00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EQZ20_00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EQZ20_00830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EQZ20_00835	COG1841	ribosomal large subunit assembly
EQZ20_00840	COG0200	Binds to the 23S rRNA
EQZ20_00845	COG0201	protein transport
EQZ20_00850	COG0563	adenylate kinase activity
EQZ20_00855	COG0024	Methionine aminopeptidase
EQZ20_00860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
EQZ20_00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EQZ20_00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EQZ20_00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EQZ20_00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EQZ20_00885	COG0202	RNA polymerase activity
EQZ20_00890	COG0203	ribosomal protein L17
EQZ20_00895	COG1122	ATPase activity
EQZ20_00900	COG1122	ATPase activity
EQZ20_00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQZ20_00910	COG0101	tRNA pseudouridine synthase activity
EQZ20_00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EQZ20_00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EQZ20_00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQZ20_00945	COG0489	protein tyrosine kinase activity
EQZ20_00955	COG2194	sulfuric ester hydrolase activity
EQZ20_00960	COG0726	polysaccharide deacetylase
EQZ20_00990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQZ20_01000	COG0385	Bile acid
EQZ20_01005	COG3876	Protein conserved in bacteria
EQZ20_01010	COG1472	Belongs to the glycosyl hydrolase 3 family
EQZ20_01015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQZ20_01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_01020	COG1263	PTS System
EQZ20_01025	COG1737	Transcriptional regulator
EQZ20_01030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EQZ20_01035	COG1683	Conserved Protein
EQZ20_01070	COG1595	DNA-templated transcription, initiation
EQZ20_01075	COG5662	AntiSigma factor
EQZ20_01080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EQZ20_01085	COG4856	YbbR-like protein
EQZ20_01090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQZ20_01095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQZ20_01100	COG5646	InterPro IPR014922
EQZ20_01105	COG0640	Transcriptional regulator
EQZ20_01110	COG2814	Major facilitator Superfamily
EQZ20_01130	COG1725	Transcriptional regulator
EQZ20_01150	COG1132	(ABC) transporter
EQZ20_01155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EQZ20_01180	COG1011	Hydrolase
EQZ20_01185	COG1113	amino acid transport
EQZ20_01195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQZ20_01230	COG1331	Highly conserved protein containing a thioredoxin domain
EQZ20_01235	COG1331	Highly conserved protein containing a thioredoxin domain
EQZ20_01240	COG1280	lysine exporter protein (LysE YggA)
EQZ20_01245	COG1331	Highly conserved protein containing a thioredoxin domain
EQZ20_01250	COG2315	Protein conserved in bacteria
EQZ20_01255	COG1331	Highly conserved protein containing a thioredoxin domain
EQZ20_01260	COG3621	Patatin-like phospholipase
EQZ20_01270	COG1733	regulation of RNA biosynthetic process
EQZ20_01275	COG0596	Alpha beta hydrolase
EQZ20_01280	COG2211	Major facilitator Superfamily
EQZ20_01285	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQZ20_01305	COG0477	Major facilitator Superfamily
EQZ20_01310	COG1794	racemase activity, acting on amino acids and derivatives
EQZ20_01345	COG0076	glutamate decarboxylase activity
EQZ20_01355	COG1846	Transcriptional regulator
EQZ20_01360	COG1033	growth of symbiont in host cell
EQZ20_01360	COG2409	Drug exporters of the RND superfamily
EQZ20_01370	COG0778	Nitroreductase
EQZ20_01375	COG1802	Transcriptional regulator
EQZ20_01380	COG0730	response to heat
EQZ20_01440	COG3409	Peptidoglycan-binding domain 1 protein
EQZ20_01455	COG1917	Cupin 2, conserved barrel domain protein
EQZ20_01455	COG2207	Transcriptional regulator
EQZ20_01470	COG0371	Dehydrogenase
EQZ20_01480	COG0535	radical SAM domain protein
EQZ20_01485	COG1266	CAAX protease self-immunity
EQZ20_01490	COG1131	(ABC) transporter
EQZ20_01500	COG1413	lyase activity
EQZ20_01505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_01530	COG3394	polysaccharide catabolic process
EQZ20_01535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_01535	COG1263	PTS System
EQZ20_01550	COG0531	amino acid
EQZ20_01555	COG2205	protein histidine kinase activity
EQZ20_01560	COG2304	oxidoreductase activity
EQZ20_01565	COG1115	amino acid carrier protein
EQZ20_01570	COG2066	Belongs to the glutaminase family
EQZ20_01575	COG4191	Histidine kinase
EQZ20_01580	COG0784	Response regulator, receiver
EQZ20_01590	COG3540	Alkaline phosphatase
EQZ20_01595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EQZ20_01600	COG0805	protein transport
EQZ20_01605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQZ20_01610	COG1012	belongs to the aldehyde dehydrogenase family
EQZ20_01615	COG2271	Major facilitator Superfamily
EQZ20_01620	COG4948	Mandelate Racemase Muconate Lactonizing
EQZ20_01625	COG2186	Transcriptional regulator
EQZ20_01630	COG2721	sulfolactate sulfo-lyase activity
EQZ20_01665	COG1846	Transcriptional regulator
EQZ20_01670	COG0318	PFAM AMP-dependent synthetase and ligase
EQZ20_01675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EQZ20_01685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQZ20_01710	COG0789	Transcriptional regulator
EQZ20_01740	COG0697	spore germination
EQZ20_01745	COG1405	negative regulation of cell septum assembly
EQZ20_01745	COG3012	SEC-C Motif Domain Protein
EQZ20_01775	COG0583	DNA-binding transcription factor activity
EQZ20_01780	COG1942	4-Oxalocrotonate Tautomerase
EQZ20_01790	COG4106	trans-aconitate 2-methyltransferase activity
EQZ20_01805	COG0252	asparaginase activity
EQZ20_01815	COG0456	acetyltransferase
EQZ20_01825	COG1164	Oligoendopeptidase f
EQZ20_01830	COG2261	transglycosylase associated protein
EQZ20_01840	COG0247	lactate metabolic process
EQZ20_01845	COG0277	FAD linked oxidase domain protein
EQZ20_01850	COG3591	Belongs to the peptidase S1B family
EQZ20_01855	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_01865	COG1595	DNA-templated transcription, initiation
EQZ20_01880	COG3773	Cell wall hydrolase
EQZ20_01885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQZ20_01890	COG3883	PFAM NLP P60 protein
EQZ20_01890	COG0791	NLP P60 protein
EQZ20_01900	COG1131	(ABC) transporter
EQZ20_01905	COG1309	transcriptional regulator
EQZ20_01930	COG2310	stress, protein
EQZ20_01935	COG2310	stress, protein
EQZ20_01940	COG2310	stress, protein
EQZ20_01945	COG0861	Integral membrane protein TerC family
EQZ20_01960	COG1358	cellular component organization or biogenesis
EQZ20_01980	COG3853	Toxic anion resistance protein (TelA)
EQZ20_01985	COG4175	Glycine betaine
EQZ20_01985	COG0517	IMP dehydrogenase activity
EQZ20_01990	COG4176	ABC-type proline glycine betaine transport system permease component
EQZ20_01995	COG2113	Glycine betaine
EQZ20_02000	COG1473	amidohydrolase
EQZ20_02010	COG2223	nitrite transmembrane transporter activity
EQZ20_02015	COG0477	Major facilitator Superfamily
EQZ20_02025	COG0039	L-malate dehydrogenase activity
EQZ20_02030	COG1620	l-lactate permease
EQZ20_02035	COG1280	lysine exporter protein (LysE YggA)
EQZ20_02040	COG1113	amino acid transport
EQZ20_02045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EQZ20_02050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EQZ20_02055	COG3541	Predicted nucleotidyltransferase
EQZ20_02065	COG1012	belongs to the aldehyde dehydrogenase family
EQZ20_02070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQZ20_02075	COG2508	Transcriptional regulator
EQZ20_02080	COG3689	TIGRFAM TIGR03943 family protein
EQZ20_02085	COG0701	Predicted permease
EQZ20_02090	COG3458	cephalosporin-C deacetylase activity
EQZ20_02115	COG0765	amino acid transport
EQZ20_02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ20_02130	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EQZ20_02135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_02145	COG1120	ATPase activity
EQZ20_02150	COG3842	ATPase activity
EQZ20_02155	COG2723	6-phospho-beta-galactosidase activity
EQZ20_02180	COG5444	nuclease activity
EQZ20_02200	COG3842	ATPase activity
EQZ20_02205	COG1176	ABC-type spermidine putrescine transport system, permease component I
EQZ20_02215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQZ20_02220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQZ20_02225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQZ20_02230	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EQZ20_02235	COG0697	spore germination
EQZ20_02240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_02255	COG3708	Transcriptional regulator
EQZ20_02255	COG2207	Transcriptional regulator
EQZ20_02260	COG2364	Membrane
EQZ20_02265	COG0673	inositol 2-dehydrogenase activity
EQZ20_02285	COG1126	abc transporter atp-binding protein
EQZ20_02290	COG0765	amino acid transport
EQZ20_02295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ20_02300	COG3829	transcription factor binding
EQZ20_02305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQZ20_02310	COG0833	amino acid
EQZ20_02315	COG0010	Belongs to the arginase family
EQZ20_02320	COG2364	Membrane
EQZ20_02325	COG1846	Transcriptional regulator
EQZ20_02330	COG0456	acetyltransferase
EQZ20_02340	COG0583	DNA-binding transcription factor activity
EQZ20_02345	COG0163	prenyltransferase activity
EQZ20_02350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EQZ20_02405	COG2972	Histidine kinase
EQZ20_02410	COG2197	response regulator
EQZ20_02415	COG4213	ABC transporter substrate-binding protein
EQZ20_02425	COG4214	carbohydrate transport
EQZ20_02430	COG2271	Major facilitator Superfamily
EQZ20_02435	COG1846	Transcriptional regulator
EQZ20_02435	COG0456	acetyltransferase
EQZ20_02450	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
EQZ20_02460	COG3104	oligopeptide transport
EQZ20_02465	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_02475	COG0697	spore germination
EQZ20_02485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EQZ20_02490	COG0789	Transcriptional regulator
EQZ20_02495	COG1136	(ABC) transporter
EQZ20_02500	COG0577	efflux transmembrane transporter activity
EQZ20_02505	COG0745	RESPONSE REGULATOR receiver
EQZ20_02510	COG5002	protein histidine kinase activity
EQZ20_02510	COG3850	Histidine kinase
EQZ20_02520	COG0527	aspartate kinase activity
EQZ20_02525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_02530	COG4605	iron ion homeostasis
EQZ20_02535	COG4604	ABC transporter, ATP-binding protein
EQZ20_02540	COG4607	ABC-type enterochelin transport system periplasmic component
EQZ20_02550	COG0778	Nitroreductase
EQZ20_02555	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EQZ20_02560	COG0640	Transcriptional regulator
EQZ20_02565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_02570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQZ20_02575	COG0531	amino acid
EQZ20_02580	COG1012	belongs to the aldehyde dehydrogenase family
EQZ20_02600	COG4549	nuclear export factor GLE1
EQZ20_02605	COG1276	copper resistance
EQZ20_02605	COG2372	response to copper ion
EQZ20_02610	COG1349	DNA-binding transcription factor activity
EQZ20_02615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQZ20_02620	COG0243	molybdopterin cofactor binding
EQZ20_02625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQZ20_02630	COG2146	nitrite reductase [NAD(P)H] activity
EQZ20_02635	COG1587	Uroporphyrinogen-III synthase
EQZ20_02635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EQZ20_02640	COG0789	Transcriptional regulator
EQZ20_02655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQZ20_02670	COG0561	phosphatase activity
EQZ20_02680	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EQZ20_02685	COG1914	H( )-stimulated, divalent metal cation uptake system
EQZ20_02690	COG4336	lyase activity
EQZ20_02695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EQZ20_02700	COG1984	allophanate hydrolase subunit 2
EQZ20_02705	COG1414	Transcriptional regulator
EQZ20_02710	COG2755	lipolytic protein G-D-S-L family
EQZ20_02715	COG2213	PTS system mannitol-specific
EQZ20_02720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_02725	COG0246	Mannitol dehydrogenase
EQZ20_02730	COG3711	transcriptional antiterminator
EQZ20_02735	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_02740	COG1917	Cupin 2, conserved barrel domain protein
EQZ20_02745	COG3871	stress protein (general stress protein 26)
EQZ20_02755	COG1316	TRANSCRIPTIONal
EQZ20_02760	COG2814	Major facilitator Superfamily
EQZ20_02770	COG1522	sequence-specific DNA binding
EQZ20_02775	COG0551	DNA topoisomerase type I activity
EQZ20_02775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQZ20_02780	COG0531	amino acid
EQZ20_02785	COG0028	Belongs to the TPP enzyme family
EQZ20_02795	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_02805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQZ20_02810	COG1914	H( )-stimulated, divalent metal cation uptake system
EQZ20_02815	COG2261	transglycosylase associated protein
EQZ20_02820	COG1027	Aspartate ammonia-lyase
EQZ20_02830	COG4876	unkown
EQZ20_02835	COG2217	Heavy metal translocating P-type atpase
EQZ20_02870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EQZ20_02875	COG3290	protein histidine kinase activity
EQZ20_02880	COG4565	transcriptional regulatory protein
EQZ20_02890	COG0628	permease
EQZ20_02895	COG1301	dicarboxylic acid transport
EQZ20_02900	COG1131	(ABC) transporter
EQZ20_02905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQZ20_02915	COG1960	acyl-CoA dehydrogenase activity
EQZ20_02930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_02935	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQZ20_02940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQZ20_02950	COG0513	Belongs to the DEAD box helicase family
EQZ20_02955	COG3402	PFAM membrane-flanked domain
EQZ20_02970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EQZ20_02980	COG0864	Transcriptional regulator
EQZ20_02985	COG2337	Toxic component of a toxin-antitoxin (TA) module
EQZ20_02990	COG1366	Belongs to the anti-sigma-factor antagonist family
EQZ20_02995	COG1366	Belongs to the anti-sigma-factor antagonist family
EQZ20_03000	COG2172	sigma factor antagonist activity
EQZ20_03005	COG2208	phosphoserine phosphatase activity
EQZ20_03020	COG1191	sigma factor activity
EQZ20_03025	COG2208	phosphoserine phosphatase activity
EQZ20_03030	COG2183	response to ionizing radiation
EQZ20_03040	COG3091	SprT-like family
EQZ20_03095	COG0457	Tetratricopeptide repeat
EQZ20_03100	COG0640	Transcriptional regulator
EQZ20_03110	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EQZ20_03115	COG4124	Belongs to the glycosyl hydrolase 26 family
EQZ20_03125	COG0697	spore germination
EQZ20_03130	COG1917	Cupin 2, conserved barrel domain protein
EQZ20_03130	COG2207	Transcriptional regulator
EQZ20_03135	COG0697	spore germination
EQZ20_03145	COG1309	transcriptional regulator
EQZ20_03150	COG0110	maltose O-acetyltransferase activity
EQZ20_03155	COG2814	Major facilitator Superfamily
EQZ20_03160	COG0789	Transcriptional regulator
EQZ20_03160	COG4978	Transcriptional regulator
EQZ20_03165	COG1114	Component of the transport system for branched-chain amino acids
EQZ20_03170	COG3621	Patatin-like phospholipase
EQZ20_03175	COG1733	regulation of RNA biosynthetic process
EQZ20_03180	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQZ20_03190	COG1113	amino acid transport
EQZ20_03195	COG1216	Glycosyl transferase, family 2
EQZ20_03195	COG1442	glycosyl transferase family 8
EQZ20_03210	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EQZ20_03225	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_03235	COG0778	Nitroreductase
EQZ20_03240	COG1846	Transcriptional regulator
EQZ20_03245	COG0596	Alpha beta hydrolase
EQZ20_03250	COG5566	PFAM Mor transcription activator
EQZ20_03255	COG1595	DNA-templated transcription, initiation
EQZ20_03265	COG2755	lipolytic protein G-D-S-L family
EQZ20_03265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EQZ20_03270	COG0494	nUDIX hydrolase
EQZ20_03275	COG2814	Major facilitator Superfamily
EQZ20_03280	COG1979	alcohol dehydrogenase
EQZ20_03285	COG0745	RESPONSE REGULATOR receiver
EQZ20_03285	COG2972	Histidine kinase
EQZ20_03295	COG2851	Citrate transporter
EQZ20_03305	COG3181	Tripartite tricarboxylate transporter family receptor
EQZ20_03310	COG4565	transcriptional regulatory protein
EQZ20_03315	COG3290	protein histidine kinase activity
EQZ20_03320	COG2814	Major facilitator Superfamily
EQZ20_03325	COG2814	Major facilitator Superfamily
EQZ20_03365	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EQZ20_03370	COG0802	atpase or kinase
EQZ20_03375	COG1214	PFAM Peptidase M22, glycoprotease
EQZ20_03380	COG0456	acetyltransferase
EQZ20_03385	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EQZ20_03390	COG0488	(ABC) transporter
EQZ20_03395	COG0315	cyclic pyranopterin monophosphate synthase activity
EQZ20_03400	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EQZ20_03405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EQZ20_03410	COG0805	protein transport
EQZ20_03420	COG1266	CAAX protease self-immunity
EQZ20_03425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EQZ20_03430	COG0459	protein refolding
EQZ20_03435	COG4974	Belongs to the 'phage' integrase family
EQZ20_03440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQZ20_03455	COG3561	AntA/AntB antirepressor
EQZ20_03570	COG1802	Transcriptional regulator
EQZ20_03570	COG4626	Terminase
EQZ20_03630	COG3953	SLT domain
EQZ20_03630	COG5280	Phage tail tape measure protein TP901
EQZ20_03640	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQZ20_03645	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_03665	COG4824	toxin secretion phage lysis holin
EQZ20_03680	COG5444	nuclease activity
EQZ20_03685	COG0457	Tetratricopeptide repeat
EQZ20_03710	COG5444	nuclease activity
EQZ20_03730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQZ20_03745	COG2323	membrane
EQZ20_03750	COG2135	peptidase activity
EQZ20_03755	COG0346	lactoylglutathione lyase activity
EQZ20_03760	COG0531	amino acid
EQZ20_03785	COG1309	transcriptional regulator
EQZ20_03790	COG0574	Belongs to the PEP-utilizing enzyme family
EQZ20_03790	COG3848	Pyruvate phosphate dikinase
EQZ20_03795	COG3189	MarR family transcriptional regulator
EQZ20_03800	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EQZ20_03805	COG2272	Belongs to the type-B carboxylesterase lipase family
EQZ20_03810	COG2814	Major facilitator Superfamily
EQZ20_03820	COG1378	Sugar-specific transcriptional regulator TrmB
EQZ20_03825	COG1280	lysine exporter protein (LysE YggA)
EQZ20_03835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQZ20_03865	COG0726	polysaccharide deacetylase
EQZ20_03875	COG1609	Transcriptional regulator
EQZ20_03880	COG0366	Alpha amylase catalytic
EQZ20_03885	COG2182	Extracellular solute-binding protein
EQZ20_03890	COG1175	transmembrane transport
EQZ20_03895	COG3833	ABC-type maltose transport systems, permease component
EQZ20_03900	COG5521	maltodextrose utilization protein MalA
EQZ20_03905	COG1554	hydrolase, family 65, central catalytic
EQZ20_03910	COG0366	Alpha amylase catalytic
EQZ20_03915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQZ20_03930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EQZ20_03935	COG0823	Involved in the tonB-independent uptake of proteins
EQZ20_03955	COG0702	epimerase
EQZ20_03960	COG2207	Transcriptional regulator
EQZ20_03960	COG3708	Transcriptional regulator
EQZ20_03965	COG2132	Multicopper oxidase
EQZ20_03975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EQZ20_03980	COG0714	Associated with various cellular activities
EQZ20_03985	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EQZ20_03990	COG1305	Transglutaminase-like
EQZ20_03995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EQZ20_03995	COG0519	Catalyzes the synthesis of GMP from XMP
EQZ20_04000	COG2252	PERMEase
EQZ20_04010	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EQZ20_04020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EQZ20_04025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQZ20_04030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EQZ20_04035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EQZ20_04040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQZ20_04045	COG0047	phosphoribosylformylglycinamidine synthase activity
EQZ20_04050	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQZ20_04055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EQZ20_04060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EQZ20_04065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EQZ20_04070	COG0138	bifunctional purine biosynthesis protein purh
EQZ20_04075	COG0151	Belongs to the GarS family
EQZ20_04085	COG2124	cytochrome p450
EQZ20_04095	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EQZ20_04100	COG1470	cell adhesion involved in biofilm formation
EQZ20_04105	COG4496	protein, YerC YecD
EQZ20_04110	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EQZ20_04115	COG0210	DNA helicase
EQZ20_04120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EQZ20_04125	COG4851	CamS sex pheromone cAM373 precursor
EQZ20_04130	COG1285	pathogenesis
EQZ20_04140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQZ20_04145	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQZ20_04150	COG0154	amidase activity
EQZ20_04155	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQZ20_04165	COG1063	alcohol dehydrogenase
EQZ20_04170	COG1309	transcriptional regulator
EQZ20_04175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQZ20_04180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQZ20_04185	COG1957	nucleoside hydrolase
EQZ20_04190	COG1597	lipid kinase activity
EQZ20_04195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQZ20_04215	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EQZ20_04220	COG0457	Tetratricopeptide repeat
EQZ20_04230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_04235	COG0697	spore germination
EQZ20_04240	COG0217	transcriptional regulatory protein
EQZ20_04265	COG0471	metal ion transport
EQZ20_04270	COG0281	malic enzyme
EQZ20_04275	COG0583	DNA-binding transcription factor activity
EQZ20_04280	COG1012	belongs to the aldehyde dehydrogenase family
EQZ20_04285	COG0840	transmembrane signaling receptor activity
EQZ20_04290	COG0109	protoheme IX farnesyltransferase activity
EQZ20_04295	COG1309	transcriptional regulator
EQZ20_04300	COG0471	metal ion transport
EQZ20_04305	COG0488	(ABC) transporter
EQZ20_04310	COG0640	Transcriptional regulator
EQZ20_04315	COG2814	Major facilitator Superfamily
EQZ20_04320	COG1469	GTP cyclohydrolase I activity
EQZ20_04325	COG0523	cobalamin synthesis protein
EQZ20_04330	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EQZ20_04335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQZ20_04340	COG0156	8-amino-7-oxononanoate synthase activity
EQZ20_04345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EQZ20_04350	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EQZ20_04355	COG2124	cytochrome p450
EQZ20_04360	COG0789	Transcriptional regulator
EQZ20_04365	COG2814	Major facilitator Superfamily
EQZ20_04370	COG0488	(ABC) transporter
EQZ20_04375	COG0513	Belongs to the DEAD box helicase family
EQZ20_04390	COG0471	metal ion transport
EQZ20_04400	COG1136	(ABC) transporter
EQZ20_04430	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EQZ20_04445	COG5658	integral membrane protein
EQZ20_04450	COG0640	Transcriptional regulator
EQZ20_04455	COG1254	Belongs to the acylphosphatase family
EQZ20_04460	COG2258	MOSC domain
EQZ20_04470	COG0024	Methionine aminopeptidase
EQZ20_04475	COG1368	sulfuric ester hydrolase activity
EQZ20_04485	COG1263	PTS System
EQZ20_04485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_04490	COG0366	Alpha amylase catalytic
EQZ20_04495	COG2188	Transcriptional regulator
EQZ20_04525	COG1215	transferase activity, transferring glycosyl groups
EQZ20_04530	COG0463	Glycosyl transferase, family 2
EQZ20_04530	COG0457	Tetratricopeptide repeat
EQZ20_04535	COG0438	transferase activity, transferring glycosyl groups
EQZ20_04550	COG0673	inositol 2-dehydrogenase activity
EQZ20_04565	COG2076	Multidrug Resistance protein
EQZ20_04570	COG1309	transcriptional regulator
EQZ20_04580	COG1733	regulation of RNA biosynthetic process
EQZ20_04585	COG0778	Nitroreductase
EQZ20_04595	COG0737	Belongs to the 5'-nucleotidase family
EQZ20_04600	COG0693	protein deglycase activity
EQZ20_04605	COG4840	Belongs to the UPF0435 family
EQZ20_04610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQZ20_04615	COG4980	gas vesicle protein
EQZ20_04620	COG1295	ribonuclease BN
EQZ20_04625	COG0477	Major facilitator Superfamily
EQZ20_04635	COG0387	Pfam Sodium calcium exchanger
EQZ20_04645	COG0535	radical SAM domain protein
EQZ20_04655	COG0726	polysaccharide deacetylase
EQZ20_04660	COG0371	Dehydrogenase
EQZ20_04675	COG0598	Magnesium transport protein CorA
EQZ20_04680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EQZ20_04685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQZ20_04690	COG4637	Psort location Cytoplasmic, score
EQZ20_04710	COG1819	glycosyl
EQZ20_04720	COG0477	Major facilitator Superfamily
EQZ20_04725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_04725	COG1263	PTS System
EQZ20_04730	COG3711	transcriptional antiterminator
EQZ20_04740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQZ20_04745	COG0022	dehydrogenase e1 component
EQZ20_04750	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQZ20_04755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQZ20_04760	COG3284	Transcriptional regulator
EQZ20_04765	COG1742	UPF0060 membrane protein
EQZ20_04770	COG1486	melibiose metabolic process
EQZ20_04775	COG1737	Transcriptional regulator
EQZ20_04780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_04780	COG1263	PTS System
EQZ20_04790	COG1733	regulation of RNA biosynthetic process
EQZ20_04795	COG2259	Doxx family
EQZ20_04800	COG2514	catechol 2,3-dioxygenase activity
EQZ20_04815	COG1917	Cupin 2, conserved barrel domain protein
EQZ20_04815	COG2207	Transcriptional regulator
EQZ20_04825	COG1309	transcriptional regulator
EQZ20_04830	COG2814	Major facilitator Superfamily
EQZ20_04835	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQZ20_04840	COG1051	belongs to the nudix hydrolase family
EQZ20_04850	COG0392	lysyltransferase activity
EQZ20_04850	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EQZ20_04855	COG0384	phenazine biosynthesis protein PhzF
EQZ20_04860	COG0778	Nitroreductase
EQZ20_04880	COG2137	regulation of response to DNA damage stimulus
EQZ20_04905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQZ20_04910	COG0463	Glycosyl transferase, family 2
EQZ20_04920	COG4485	Bacterial membrane protein, YfhO
EQZ20_04925	COG1988	membrane-bound metal-dependent
EQZ20_04930	COG1194	a g-specific adenine glycosylase
EQZ20_04940	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_04955	COG3557	Belongs to the UPF0374 family
EQZ20_04960	COG1132	(ABC) transporter
EQZ20_04970	COG0444	Belongs to the ABC transporter superfamily
EQZ20_04975	COG4608	Belongs to the ABC transporter superfamily
EQZ20_04980	COG0747	negative chemotaxis
EQZ20_04995	COG4129	membrane
EQZ20_05000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQZ20_05005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EQZ20_05010	COG0735	belongs to the Fur family
EQZ20_05140	COG0710	3-dehydroquinate dehydratase activity
EQZ20_05145	COG4326	sporulation control protein
EQZ20_05150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EQZ20_05155	COG1116	anion transmembrane transporter activity
EQZ20_05160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQZ20_05165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQZ20_05170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQZ20_05180	COG1476	TRANSCRIPTIONal
EQZ20_05190	COG1122	ATPase activity
EQZ20_05210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQZ20_05220	COG3382	B3 4 domain protein
EQZ20_05225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EQZ20_05235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EQZ20_05240	COG0789	Transcriptional regulator
EQZ20_05245	COG1664	Polymer-forming cytoskeletal
EQZ20_05255	COG2766	serine protein kinase
EQZ20_05260	COG2718	Belongs to the UPF0229 family
EQZ20_05265	COG1566	PFAM secretion protein HlyD family protein
EQZ20_05270	COG2814	Major facilitator Superfamily
EQZ20_05275	COG0655	NAD(P)H dehydrogenase (quinone) activity
EQZ20_05290	COG1725	Transcriptional regulator
EQZ20_05295	COG1131	(ABC) transporter
EQZ20_05300	COG1131	(ABC) transporter
EQZ20_05305	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQZ20_05310	COG1278	Cold shock
EQZ20_05315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQZ20_05320	COG2011	ABC-type metal ion transport system permease component
EQZ20_05325	COG1464	Belongs to the NlpA lipoprotein family
EQZ20_05330	COG1823	symporter activity
EQZ20_05360	COG5577	PFAM Coat F domain
EQZ20_05365	COG5002	protein histidine kinase activity
EQZ20_05370	COG4085	toxin activity
EQZ20_05370	COG1525	nuclease
EQZ20_05370	COG0737	Belongs to the 5'-nucleotidase family
EQZ20_05375	COG3764	Sortase (surface protein transpeptidase)
EQZ20_05380	COG0517	IMP dehydrogenase activity
EQZ20_05380	COG1125	glycine betaine transport
EQZ20_05385	COG1174	glycine betaine transport
EQZ20_05390	COG1732	Glycine betaine
EQZ20_05395	COG1174	glycine betaine transport
EQZ20_05400	COG0564	pseudouridine synthase activity
EQZ20_05410	COG0517	IMP dehydrogenase activity
EQZ20_05415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQZ20_05420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQZ20_05420	COG3153	acetyltransferase
EQZ20_05425	COG0488	(ABC) transporter
EQZ20_05440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQZ20_05445	COG0604	alcohol dehydrogenase
EQZ20_05450	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EQZ20_05455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQZ20_05460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQZ20_05465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EQZ20_05470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQZ20_05485	COG2203	Gaf domain
EQZ20_05485	COG4585	Histidine kinase
EQZ20_05490	COG2197	response regulator
EQZ20_05510	COG1959	2 iron, 2 sulfur cluster binding
EQZ20_05515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQZ20_05515	COG1017	nitric oxide dioxygenase activity
EQZ20_05520	COG2719	SpoVR family
EQZ20_05525	COG1785	Belongs to the alkaline phosphatase family
EQZ20_05535	COG0791	NLP P60 protein
EQZ20_05535	COG1388	LysM domain
EQZ20_05540	COG0583	DNA-binding transcription factor activity
EQZ20_05545	COG0372	Belongs to the citrate synthase family
EQZ20_05550	COG1846	Transcriptional regulator
EQZ20_05555	COG0531	amino acid
EQZ20_05560	COG0733	neurotransmitter:sodium symporter activity
EQZ20_05570	COG3708	Transcriptional regulator
EQZ20_05570	COG2207	Transcriptional regulator
EQZ20_05575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_05595	COG1595	DNA-templated transcription, initiation
EQZ20_05600	COG0204	Acyl-transferase
EQZ20_05615	COG1253	flavin adenine dinucleotide binding
EQZ20_05620	COG0789	Transcriptional regulator
EQZ20_05625	COG1253	flavin adenine dinucleotide binding
EQZ20_05645	COG3739	integral membrane protein
EQZ20_05650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQZ20_05655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQZ20_05660	COG0584	glycerophosphoryl diester phosphodiesterase
EQZ20_05670	COG0668	transmembrane transport
EQZ20_05675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EQZ20_05685	COG0454	-acetyltransferase
EQZ20_05690	COG0726	polysaccharide deacetylase
EQZ20_05700	COG1757	Na H antiporter
EQZ20_05705	COG2017	converts alpha-aldose to the beta-anomer
EQZ20_05730	COG0589	response to stress
EQZ20_05740	COG1132	(ABC) transporter
EQZ20_05745	COG1132	(ABC) transporter
EQZ20_05750	COG0702	epimerase
EQZ20_05765	COG3842	ATPase activity
EQZ20_05770	COG2508	Transcriptional regulator
EQZ20_05780	COG0189	ligase activity
EQZ20_05785	COG0189	ligase activity
EQZ20_05790	COG4399	Belongs to the UPF0754 family
EQZ20_05795	COG3679	Belongs to the UPF0342 family
EQZ20_05800	COG0561	phosphatase activity
EQZ20_05805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQZ20_05820	COG0475	glutathione-regulated potassium exporter activity
EQZ20_05825	COG0490	domain, Protein
EQZ20_05835	COG1024	Enoyl-CoA hydratase
EQZ20_05840	COG0457	Tetratricopeptide repeat
EQZ20_05850	COG4152	abc transporter atp-binding protein
EQZ20_05855	COG1668	transmembrane transport
EQZ20_05860	COG0420	3'-5' exonuclease activity
EQZ20_05865	COG4717	serine-type aminopeptidase activity
EQZ20_05870	COG3481	metal-dependent phosphohydrolase, HD sub domain
EQZ20_05880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQZ20_05915	COG1846	Transcriptional regulator
EQZ20_05920	COG4980	gas vesicle protein
EQZ20_05935	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EQZ20_05940	COG0537	adenosine 5'-monophosphoramidase activity
EQZ20_05950	COG1131	(ABC) transporter
EQZ20_05955	COG4473	ABC transporter
EQZ20_05965	COG1473	amidohydrolase
EQZ20_05980	COG2329	Antibiotic biosynthesis monooxygenase
EQZ20_05985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQZ20_05990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EQZ20_06010	COG1309	transcriptional regulator
EQZ20_06015	COG1511	domain protein
EQZ20_06020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQZ20_06025	COG1363	Peptidase, m42
EQZ20_06030	COG1301	dicarboxylic acid transport
EQZ20_06040	COG1234	tRNA 3'-trailer cleavage
EQZ20_06045	COG0095	Lipoate-protein ligase
EQZ20_06055	COG0318	PFAM AMP-dependent synthetase and ligase
EQZ20_06065	COG1396	sequence-specific DNA binding
EQZ20_06080	COG0501	Belongs to the peptidase M48B family
EQZ20_06090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EQZ20_06095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_06100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_06105	COG0406	alpha-ribazole phosphatase activity
EQZ20_06110	COG0840	transmembrane signaling receptor activity
EQZ20_06115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQZ20_06115	COG0723	plastoquinol--plastocyanin reductase activity
EQZ20_06120	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_06135	COG4903	ComK protein
EQZ20_06145	COG0398	Pfam SNARE associated Golgi protein
EQZ20_06150	COG0681	Belongs to the peptidase S26 family
EQZ20_06155	COG1404	Belongs to the peptidase S8 family
EQZ20_06160	COG0457	Tetratricopeptide repeat
EQZ20_06185	COG1486	melibiose metabolic process
EQZ20_06190	COG3180	Ammonia monooxygenase
EQZ20_06205	COG3546	catalase activity
EQZ20_06210	COG0318	PFAM AMP-dependent synthetase and ligase
EQZ20_06220	COG2720	vancomycin resistance protein
EQZ20_06225	COG5002	protein histidine kinase activity
EQZ20_06230	COG0745	RESPONSE REGULATOR receiver
EQZ20_06235	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EQZ20_06240	COG0725	ABC transporter, periplasmic molybdate-binding protein
EQZ20_06245	COG4149	molybdate abc transporter
EQZ20_06250	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EQZ20_06255	COG1074	ATP-dependent DNA helicase activity
EQZ20_06260	COG0420	3'-5' exonuclease activity
EQZ20_06265	COG0419	ATPase involved in DNA repair
EQZ20_06310	COG5337	Spore coat protein CotH
EQZ20_06320	COG0179	Fumarylacetoacetate (FAA) hydrolase
EQZ20_06340	COG0367	asparagine synthase
EQZ20_06345	COG0534	Mate efflux family protein
EQZ20_06350	COG2207	Transcriptional regulator
EQZ20_06350	COG1917	Cupin 2, conserved barrel domain protein
EQZ20_06360	COG1609	Transcriptional regulator
EQZ20_06365	COG0673	inositol 2-dehydrogenase activity
EQZ20_06370	COG2226	methyltransferase
EQZ20_06390	COG1279	arginine transmembrane transporter activity
EQZ20_06395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_06405	COG0076	glutamate decarboxylase activity
EQZ20_06410	COG4264	IucA IucC family
EQZ20_06430	COG2153	protein acetylation
EQZ20_06435	COG1410	methionine synthase
EQZ20_06435	COG0646	methionine synthase
EQZ20_06440	COG0646	methionine synthase
EQZ20_06440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EQZ20_06445	COG1666	GTP binding
EQZ20_06450	COG2996	Protein conserved in bacteria
EQZ20_06465	COG1307	EDD domain protein, DegV family
EQZ20_06470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ20_06480	COG0516	GMP reductase activity
EQZ20_06490	COG0561	phosphatase activity
EQZ20_06495	COG1073	alpha beta
EQZ20_06500	COG2151	metal-sulfur cluster biosynthetic enzyme
EQZ20_06510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EQZ20_06515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EQZ20_06520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EQZ20_06525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQZ20_06530	COG0505	Belongs to the CarA family
EQZ20_06535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQZ20_06540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EQZ20_06555	COG2267	carboxylic ester hydrolase activity
EQZ20_06565	COG1744	ABC transporter substrate-binding protein PnrA-like
EQZ20_06580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQZ20_06585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQZ20_06590	COG5504	Zn-dependent protease
EQZ20_06595	COG0444	Belongs to the ABC transporter superfamily
EQZ20_06600	COG4608	Belongs to the ABC transporter superfamily
EQZ20_06610	COG0601	transmembrane transport
EQZ20_06615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQZ20_06625	COG0180	Tryptophanyl-tRNA synthetase
EQZ20_06630	COG4166	transmembrane transport
EQZ20_06635	COG0601	transmembrane transport
EQZ20_06640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQZ20_06645	COG0444	Belongs to the ABC transporter superfamily
EQZ20_06650	COG4608	Belongs to the ABC transporter superfamily
EQZ20_06655	COG0456	acetyltransferase
EQZ20_06660	COG1393	Belongs to the ArsC family
EQZ20_06665	COG0861	Integral membrane protein TerC family
EQZ20_06675	COG4862	establishment of competence for transformation
EQZ20_06680	COG4469	Competence protein
EQZ20_06685	COG1164	Oligoendopeptidase f
EQZ20_06700	COG2346	COG2346, Truncated hemoglobins
EQZ20_06705	COG0741	lytic transglycosylase activity
EQZ20_06710	COG4116	CYTH
EQZ20_06720	COG2357	RelA SpoT domain protein
EQZ20_06725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQZ20_06730	COG0564	pseudouridine synthase activity
EQZ20_06735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EQZ20_06740	COG0569	domain protein
EQZ20_06740	COG0475	glutathione-regulated potassium exporter activity
EQZ20_06745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQZ20_06750	COG0352	thiamine-phosphate diphosphorylase activity
EQZ20_06760	COG2104	thiamine diphosphate biosynthetic process
EQZ20_06765	COG2022	thiamine diphosphate biosynthetic process
EQZ20_06770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQZ20_06775	COG0351	phosphomethylpyrimidine kinase
EQZ20_06780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EQZ20_06835	COG0210	DNA helicase
EQZ20_06845	COG0586	Pfam SNARE associated Golgi protein
EQZ20_06850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQZ20_06855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQZ20_06860	COG2246	polysaccharide biosynthetic process
EQZ20_06865	COG2153	protein acetylation
EQZ20_06870	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQZ20_06875	COG2382	esterase
EQZ20_06890	COG0626	cystathionine gamma-synthase activity
EQZ20_06895	COG0626	cystathionine gamma-synthase activity
EQZ20_07055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ20_07055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ20_07060	COG2176	DNA-directed DNA polymerase activity
EQZ20_07100	COG1780	Probably involved in ribonucleotide reductase function
EQZ20_07105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQZ20_07130	COG0756	dUTP diphosphatase activity
EQZ20_07140	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EQZ20_07145	COG3584	3D domain protein
EQZ20_07250	COG0582	viral genome integration into host DNA
EQZ20_07345	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_07370	COG1388	LysM domain
EQZ20_07370	COG3409	Peptidoglycan-binding domain 1 protein
EQZ20_07370	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQZ20_07400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EQZ20_07405	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_07410	COG0346	lactoylglutathione lyase activity
EQZ20_07455	COG1082	Xylose isomerase domain protein TIM barrel
EQZ20_07460	COG0673	inositol 2-dehydrogenase activity
EQZ20_07465	COG0531	amino acid
EQZ20_07475	COG0583	DNA-binding transcription factor activity
EQZ20_07480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQZ20_07485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQZ20_07490	COG0583	DNA-binding transcription factor activity
EQZ20_07495	COG0697	spore germination
EQZ20_07500	COG0346	lactoylglutathione lyase activity
EQZ20_07510	COG3584	3D domain protein
EQZ20_07510	COG1388	LysM domain
EQZ20_07520	COG2814	Major facilitator Superfamily
EQZ20_07525	COG1309	transcriptional regulator
EQZ20_07535	COG4195	phage-related replication protein
EQZ20_07540	COG2856	Zn peptidase
EQZ20_07545	COG1396	sequence-specific DNA binding
EQZ20_07555	COG1522	sequence-specific DNA binding
EQZ20_07560	COG1484	DNA-dependent DNA replication
EQZ20_07580	COG0584	glycerophosphoryl diester phosphodiesterase
EQZ20_07600	COG1802	Transcriptional regulator
EQZ20_07605	COG1063	alcohol dehydrogenase
EQZ20_07610	COG1312	Catalyzes the dehydration of D-mannonate
EQZ20_07615	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_07620	COG1063	alcohol dehydrogenase
EQZ20_07640	COG0306	phosphate transporter
EQZ20_07645	COG1392	Phosphate transport regulator
EQZ20_07650	COG0405	Gamma-glutamyltransferase
EQZ20_07655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EQZ20_07665	COG4208	sulfate ABC transporter
EQZ20_07675	COG5578	integral membrane protein
EQZ20_07680	COG2972	Histidine kinase
EQZ20_07685	COG4753	response regulator
EQZ20_07685	COG2207	Transcriptional regulator
EQZ20_07690	COG1653	transport
EQZ20_07695	COG1175	transmembrane transport
EQZ20_07700	COG0395	ABC-type sugar transport system, permease component
EQZ20_07705	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EQZ20_07720	COG0531	amino acid
EQZ20_07725	COG0346	lactoylglutathione lyase activity
EQZ20_07730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQZ20_07735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQZ20_07740	COG2362	D-Aminopeptidase
EQZ20_07745	COG0601	transmembrane transport
EQZ20_07750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQZ20_07755	COG0444	Belongs to the ABC transporter superfamily
EQZ20_07760	COG4166	transmembrane transport
EQZ20_07765	COG1619	proteins homologs of microcin C7 resistance protein MccF
EQZ20_07770	COG4948	Mandelate Racemase Muconate Lactonizing
EQZ20_07775	COG0791	NLP P60 protein
EQZ20_07780	COG4608	Belongs to the ABC transporter superfamily
EQZ20_07790	COG1834	amidinotransferase
EQZ20_07795	COG1607	acyl-coa hydrolase
EQZ20_07805	COG2318	DinB family
EQZ20_07810	COG2076	Multidrug Resistance protein
EQZ20_07815	COG2076	Multidrug Resistance protein
EQZ20_07820	COG0788	formyltetrahydrofolate deformylase activity
EQZ20_07825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EQZ20_07830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EQZ20_07835	COG1764	response to oxidative stress
EQZ20_07845	COG1846	Transcriptional regulator
EQZ20_07850	COG1764	response to oxidative stress
EQZ20_07860	COG0590	tRNA wobble adenosine to inosine editing
EQZ20_07865	COG0406	alpha-ribazole phosphatase activity
EQZ20_07885	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQZ20_07890	COG1404	Belongs to the peptidase S8 family
EQZ20_07900	COG2239	Acts as a magnesium transporter
EQZ20_07910	COG0789	Transcriptional regulator
EQZ20_07925	COG1846	Transcriptional regulator
EQZ20_07930	COG3285	dna ligase
EQZ20_07930	COG1793	dna ligase
EQZ20_07935	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EQZ20_07940	COG5001	Diguanylate cyclase
EQZ20_07940	COG3300	MHYT domain
EQZ20_07945	COG0586	Pfam SNARE associated Golgi protein
EQZ20_07950	COG0861	Integral membrane protein TerC family
EQZ20_07960	COG1191	sigma factor activity
EQZ20_07980	COG0501	Belongs to the peptidase M48B family
EQZ20_07985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQZ20_07995	COG0768	penicillin binding
EQZ20_08005	COG3594	Acyltransferase
EQZ20_08010	COG5002	protein histidine kinase activity
EQZ20_08015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQZ20_08020	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EQZ20_08025	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EQZ20_08030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQZ20_08035	COG0436	Aminotransferase
EQZ20_08040	COG1850	ribulose-bisphosphate carboxylase activity
EQZ20_08045	COG0235	Class ii aldolase
EQZ20_08045	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EQZ20_08050	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EQZ20_08050	COG0235	Class ii aldolase
EQZ20_08055	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EQZ20_08060	COG0346	lactoylglutathione lyase activity
EQZ20_08065	COG3339	Conserved Protein
EQZ20_08075	COG3852	Histidine kinase
EQZ20_08080	COG1846	Transcriptional regulator
EQZ20_08085	COG1360	Flagellar Motor Protein
EQZ20_08090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EQZ20_08095	COG0542	response to heat
EQZ20_08100	COG3949	Membrane
EQZ20_08105	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EQZ20_08110	COG0720	synthase
EQZ20_08115	COG0602	queuosine metabolic process
EQZ20_08120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EQZ20_08140	COG0456	acetyltransferase
EQZ20_08170	COG4873	Protein conserved in bacteria
EQZ20_08180	COG3773	Cell wall hydrolase
EQZ20_08190	COG2244	polysaccharide biosynthetic process
EQZ20_08195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_08200	COG2217	Heavy metal translocating P-type atpase
EQZ20_08210	COG0006	proline dipeptidase activity
EQZ20_08215	COG1609	Transcriptional regulator
EQZ20_08220	COG3711	transcriptional antiterminator
EQZ20_08225	COG2190	(PTS) system
EQZ20_08225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_08225	COG1263	PTS System
EQZ20_08230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_08235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EQZ20_08250	COG1533	DNA photolyase activity
EQZ20_08255	COG0456	acetyltransferase
EQZ20_08260	COG0840	transmembrane signaling receptor activity
EQZ20_08265	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_08270	COG2084	Dehydrogenase
EQZ20_08280	COG2340	Cysteine-rich secretory protein family
EQZ20_08285	COG0768	penicillin binding
EQZ20_08290	COG4191	Histidine kinase
EQZ20_08295	COG0436	Aminotransferase
EQZ20_08310	COG0835	chemotaxis
EQZ20_08310	COG0784	Response regulator, receiver
EQZ20_08325	COG2814	Major facilitator Superfamily
EQZ20_08330	COG1376	ErfK ybiS ycfS ynhG family protein
EQZ20_08335	COG1408	metallophosphoesterase
EQZ20_08340	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_08345	COG2200	EAL domain
EQZ20_08350	COG4703	Protein of unknown function (DUF1797)
EQZ20_08355	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EQZ20_08365	COG0517	IMP dehydrogenase activity
EQZ20_08370	COG0583	DNA-binding transcription factor activity
EQZ20_08375	COG0716	FMN binding
EQZ20_08385	COG0716	FMN binding
EQZ20_08390	COG2171	N-acyltransferase activity
EQZ20_08395	COG1473	amidohydrolase
EQZ20_08405	COG0450	alkyl hydroperoxide reductase
EQZ20_08410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_08425	COG0746	molybdenum cofactor guanylyltransferase activity
EQZ20_08430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQZ20_08435	COG0303	'Molybdopterin
EQZ20_08440	COG1763	Mo-molybdopterin cofactor biosynthetic process
EQZ20_08445	COG0314	molybdopterin synthase activity
EQZ20_08450	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EQZ20_08460	COG1132	(ABC) transporter
EQZ20_08465	COG1132	(ABC) transporter
EQZ20_08475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQZ20_08480	COG1136	(ABC) transporter
EQZ20_08485	COG0577	efflux transmembrane transporter activity
EQZ20_08495	COG1349	DNA-binding transcription factor activity
EQZ20_08500	COG1105	Belongs to the carbohydrate kinase PfkB family
EQZ20_08505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_08505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQZ20_08505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQZ20_08525	COG0488	(ABC) transporter
EQZ20_08530	COG2309	aminopeptidase activity
EQZ20_08540	COG1077	Cell shape determining protein MreB Mrl
EQZ20_08545	COG2002	toxin-antitoxin pair type II binding
EQZ20_08550	COG3852	Histidine kinase
EQZ20_08555	COG0569	domain protein
EQZ20_08560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EQZ20_08570	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQZ20_08585	COG0242	peptide deformylase activity
EQZ20_08595	COG0497	DNA recombination
EQZ20_08600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQZ20_08605	COG0022	dehydrogenase e1 component
EQZ20_08610	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQZ20_08615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQZ20_08620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_08630	COG1982	Orn Lys Arg decarboxylase major
EQZ20_08635	COG4476	Belongs to the UPF0223 family
EQZ20_08650	COG4493	Belongs to the UPF0637 family
EQZ20_08660	COG0483	inositol monophosphate 1-phosphatase activity
EQZ20_08685	COG1846	Transcriptional regulator
EQZ20_08690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EQZ20_08695	COG4896	Protein conserved in bacteria
EQZ20_08705	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EQZ20_08715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EQZ20_08720	COG2066	Belongs to the glutaminase family
EQZ20_08725	COG4838	Belongs to the UPF0358 family
EQZ20_08730	COG0772	Belongs to the SEDS family
EQZ20_08735	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EQZ20_08740	COG1612	heme a metabolic process
EQZ20_08745	COG0109	protoheme IX farnesyltransferase activity
EQZ20_08750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQZ20_08750	COG2010	Cytochrome c
EQZ20_08755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQZ20_08760	COG1845	cytochrome c oxidase, subunit III
EQZ20_08765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQZ20_08770	COG3336	cytochrome c oxidase
EQZ20_08780	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EQZ20_08785	COG2340	Cysteine-rich secretory protein family
EQZ20_08790	COG0583	DNA-binding transcription factor activity
EQZ20_08795	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQZ20_08805	COG1834	amidinotransferase
EQZ20_08820	COG3679	Belongs to the UPF0342 family
EQZ20_08825	COG4471	UPF0298 protein
EQZ20_08830	COG0742	ribosomal rna small subunit methyltransferase
EQZ20_08835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EQZ20_08840	COG3314	Sporulation integral membrane protein YlbJ
EQZ20_08845	COG3480	Lon protease (S16) C-terminal proteolytic domain
EQZ20_08850	COG1323	Belongs to the UPF0348 family
EQZ20_08855	COG1399	metal-binding, possibly nucleic acid-binding protein
EQZ20_08860	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EQZ20_08870	COG0454	-acetyltransferase
EQZ20_08875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EQZ20_08880	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EQZ20_08885	COG2001	Belongs to the MraZ family
EQZ20_08890	COG0275	rRNA processing
EQZ20_08895	COG4839	cell division protein FtsL
EQZ20_08905	COG0768	penicillin binding
EQZ20_08910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EQZ20_08915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQZ20_08920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQZ20_08925	COG0772	Belongs to the SEDS family
EQZ20_08930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQZ20_08935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EQZ20_08940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EQZ20_08945	COG3879	Bacterial protein of unknown function (DUF881)
EQZ20_08950	COG3879	Bacterial protein of unknown function (DUF881)
EQZ20_08955	COG3856	small basic protein
EQZ20_08960	COG0849	cell division
EQZ20_08965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EQZ20_08970	COG1404	Belongs to the peptidase S8 family
EQZ20_08970	COG4412	M6 family metalloprotease domain protein
EQZ20_08975	COG1404	Belongs to the peptidase S8 family
EQZ20_08975	COG4412	M6 family metalloprotease domain protein
EQZ20_08985	COG1191	sigma factor activity
EQZ20_08990	COG1191	sigma factor activity
EQZ20_08995	COG1119	ATPase activity
EQZ20_09005	COG1873	PFAM PRC-barrel domain
EQZ20_09015	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EQZ20_09020	COG1799	cell septum assembly
EQZ20_09025	COG0762	integral membrane protein
EQZ20_09030	COG2302	S4 RNA-binding domain
EQZ20_09035	COG3599	regulation of cell shape
EQZ20_09040	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EQZ20_09045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQZ20_09050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EQZ20_09055	COG0564	pseudouridine synthase activity
EQZ20_09060	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EQZ20_09065	COG2233	PERMEase
EQZ20_09070	COG0540	Belongs to the ATCase OTCase family
EQZ20_09075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EQZ20_09080	COG0505	Belongs to the CarA family
EQZ20_09085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQZ20_09090	COG0543	2 iron, 2 sulfur cluster binding
EQZ20_09095	COG0167	dihydroorotate dehydrogenase activity
EQZ20_09100	COG0284	orotidine-5'-phosphate decarboxylase activity
EQZ20_09105	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EQZ20_09115	COG0175	sulfate reduction
EQZ20_09120	COG0306	phosphate transporter
EQZ20_09125	COG2046	Belongs to the sulfate adenylyltransferase family
EQZ20_09130	COG0529	Catalyzes the synthesis of activated sulfate
EQZ20_09135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EQZ20_09140	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EQZ20_09145	COG1648	precorrin-2 dehydrogenase activity
EQZ20_09160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EQZ20_09165	COG1561	YicC-like family, N-terminal region
EQZ20_09170	COG2052	Domain of unknown function (DUF370)
EQZ20_09175	COG0194	GDP metabolic process
EQZ20_09180	COG1758	RNA polymerase activity
EQZ20_09185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQZ20_09190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQZ20_09195	COG0242	peptide deformylase activity
EQZ20_09200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EQZ20_09205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQZ20_09205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQZ20_09210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EQZ20_09215	COG0631	protein serine/threonine phosphatase activity
EQZ20_09220	COG2815	serine threonine protein kinase
EQZ20_09220	COG0515	serine threonine protein kinase
EQZ20_09225	COG1162	GTPase activity
EQZ20_09230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQZ20_09235	COG1564	THIamine pyrophosphokinase
EQZ20_09245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EQZ20_09250	COG1302	Protein conserved in bacteria
EQZ20_09255	COG1461	Dihydroxyacetone kinase
EQZ20_09260	COG1760	l-serine dehydratase
EQZ20_09265	COG1760	l-serine dehydratase
EQZ20_09270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EQZ20_09275	COG1349	DNA-binding transcription factor activity
EQZ20_09280	COG0416	fatty acid biosynthetic process
EQZ20_09285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EQZ20_09290	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_09295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQZ20_09300	COG0571	ribonuclease III activity
EQZ20_09305	COG1196	nuclear chromosome segregation
EQZ20_09310	COG0552	protein localization to endoplasmic reticulum
EQZ20_09315	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EQZ20_09320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EQZ20_09325	COG0228	four-way junction DNA binding
EQZ20_09330	COG1837	Belongs to the UPF0109 family
EQZ20_09340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EQZ20_09345	COG0336	Belongs to the RNA methyltransferase TrmD family
EQZ20_09350	COG0335	large ribosomal subunit rRNA binding
EQZ20_09360	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQZ20_09365	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQZ20_09375	COG2257	FlhB HrpN YscU SpaS Family
EQZ20_09380	COG0045	succinate-CoA ligase (ADP-forming) activity
EQZ20_09385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EQZ20_09390	COG0758	DNA mediated transformation
EQZ20_09395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQZ20_09400	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EQZ20_09405	COG4974	Belongs to the 'phage' integrase family
EQZ20_09410	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EQZ20_09415	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EQZ20_09420	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EQZ20_09425	COG1815	bacterial-type flagellum-dependent cell motility
EQZ20_09430	COG1558	bacterial-type flagellum-dependent cell motility
EQZ20_09435	COG1677	Flagellar hook-basal body complex protein FliE
EQZ20_09440	COG1766	The M ring may be actively involved in energy transduction
EQZ20_09445	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQZ20_09450	COG1317	bacterial-type flagellum organization
EQZ20_09455	COG1157	protein secretion by the type III secretion system
EQZ20_09460	COG2882	bacterial-type flagellum organization
EQZ20_09470	COG3144	bacterial-type flagellum assembly
EQZ20_09475	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EQZ20_09480	COG4786	Flagellar basal body rod
EQZ20_09485	COG1582	Flagellar protein (FlbD)
EQZ20_09490	COG1580	Controls the rotational direction of flagella during chemotaxis
EQZ20_09495	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQZ20_09500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQZ20_09500	COG1776	CheC inhibitor of MCP methylation
EQZ20_09505	COG2201	protein-glutamate methylesterase activity
EQZ20_09510	COG3190	flagellar
EQZ20_09515	COG1338	Plays a role in the flagellum-specific transport system
EQZ20_09520	COG1987	bacterial-type flagellum assembly
EQZ20_09525	COG1684	flagellar biosynthetic protein fliR
EQZ20_09530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EQZ20_09535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EQZ20_09540	COG1419	protein localization to endoplasmic reticulum
EQZ20_09545	COG0455	bacterial-type flagellum organization
EQZ20_09550	COG2201	protein-glutamate methylesterase activity
EQZ20_09555	COG0643	Histidine kinase
EQZ20_09555	COG2198	Histidine kinase
EQZ20_09560	COG0835	chemotaxis
EQZ20_09565	COG1776	CheC inhibitor of MCP methylation
EQZ20_09570	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EQZ20_09575	COG1191	sigma factor activity
EQZ20_09585	COG0052	Belongs to the universal ribosomal protein uS2 family
EQZ20_09590	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EQZ20_09595	COG0528	UMP kinase activity
EQZ20_09600	COG0233	cytoplasmic translational termination
EQZ20_09605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EQZ20_09610	COG4589	Belongs to the CDS family
EQZ20_09615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EQZ20_09620	COG0750	zinc metalloprotease
EQZ20_09625	COG0442	prolyl-tRNA aminoacylation
EQZ20_09630	COG2176	DNA-directed DNA polymerase activity
EQZ20_09655	COG0779	Required for maturation of 30S ribosomal subunits
EQZ20_09660	COG0195	Participates in both transcription termination and antitermination
EQZ20_09665	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EQZ20_09670	COG1358	cellular component organization or biogenesis
EQZ20_09675	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EQZ20_09680	COG1550	Protein conserved in bacteria
EQZ20_09685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EQZ20_09690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EQZ20_09695	COG0196	riboflavin kinase activity
EQZ20_09700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EQZ20_09705	COG1185	polyribonucleotide nucleotidyltransferase activity
EQZ20_09710	COG0726	polysaccharide deacetylase
EQZ20_09715	COG0612	Peptidase, M16
EQZ20_09720	COG1873	PFAM PRC-barrel domain
EQZ20_09730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQZ20_09740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EQZ20_09745	COG5444	nuclease activity
EQZ20_09775	COG0457	Tetratricopeptide repeat
EQZ20_09800	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQZ20_09805	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_09815	COG2433	Pfam Transposase IS66
EQZ20_09825	COG1196	nuclear chromosome segregation
EQZ20_09825	COG0739	heme binding
EQZ20_09825	COG0741	lytic transglycosylase activity
EQZ20_09830	COG0739	heme binding
EQZ20_09830	COG0741	lytic transglycosylase activity
EQZ20_09830	COG1196	nuclear chromosome segregation
EQZ20_09935	COG0582	viral genome integration into host DNA
EQZ20_10030	COG4373	Mu-like prophage FluMu protein gp28
EQZ20_10090	COG1404	Belongs to the peptidase S8 family
EQZ20_10160	COG3655	Transcriptional regulator
EQZ20_10260	COG0582	viral genome integration into host DNA
EQZ20_10340	COG1793	dna ligase
EQZ20_10420	COG2887	Belongs to the helicase family. UvrD subfamily
EQZ20_10430	COG0305	Participates in initiation and elongation during chromosome replication
EQZ20_10435	COG0358	DNA primase activity
EQZ20_10440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQZ20_10445	COG0587	DNA-directed DNA polymerase activity
EQZ20_10460	COG3584	3D domain protein
EQZ20_10500	COG1780	Probably involved in ribonucleotide reductase function
EQZ20_10505	COG1372	Participates in initiation and elongation during chromosome replication
EQZ20_10505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQZ20_10515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQZ20_10540	COG0756	dUTP diphosphatase activity
EQZ20_10565	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EQZ20_10620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EQZ20_10630	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EQZ20_10635	COG3331	DNA recombination
EQZ20_10645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQZ20_10650	COG0527	aspartate kinase activity
EQZ20_10660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQZ20_10665	COG0740	serine-type endopeptidase activity
EQZ20_10675	COG1674	ftsk spoiiie
EQZ20_10675	COG4980	gas vesicle protein
EQZ20_10680	COG2188	Transcriptional regulator
EQZ20_10685	COG2814	Major facilitator Superfamily
EQZ20_10690	COG0612	Peptidase, M16
EQZ20_10695	COG0612	Peptidase, M16
EQZ20_10700	COG0300	oxidoreductase activity
EQZ20_10715	COG1426	Protein conserved in bacteria
EQZ20_10720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EQZ20_10725	COG1546	Belongs to the CinA family
EQZ20_10725	COG1058	Belongs to the CinA family
EQZ20_10730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EQZ20_10735	COG1418	mRNA catabolic process
EQZ20_10740	COG1692	metallophosphoesterase
EQZ20_10745	COG2359	stage V sporulation protein S
EQZ20_10755	COG1063	alcohol dehydrogenase
EQZ20_10760	COG0156	8-amino-7-oxononanoate synthase activity
EQZ20_10765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQZ20_10770	COG4550	Control of competence regulator ComK, YlbF/YmcA
EQZ20_10780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQZ20_10785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EQZ20_10795	COG0457	Tetratricopeptide repeat
EQZ20_10800	COG5444	nuclease activity
EQZ20_10830	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EQZ20_10835	COG0346	lactoylglutathione lyase activity
EQZ20_10865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EQZ20_10875	COG0402	S-adenosylhomocysteine deaminase activity
EQZ20_10910	COG2323	membrane
EQZ20_10915	COG3619	membrane
EQZ20_10925	COG2814	Major facilitator Superfamily
EQZ20_10930	COG0393	Putative heavy-metal-binding
EQZ20_10935	COG0398	Pfam SNARE associated Golgi protein
EQZ20_10940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQZ20_10945	COG1819	glycosyl
EQZ20_10950	COG0531	amino acid
EQZ20_10970	COG1309	transcriptional regulator
EQZ20_10975	COG3631	Ketosteroid isomerase-related protein
EQZ20_10980	COG0702	epimerase
EQZ20_10985	COG1764	response to oxidative stress
EQZ20_10990	COG2076	Multidrug Resistance protein
EQZ20_10995	COG2076	Multidrug Resistance protein
EQZ20_11010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EQZ20_11015	COG1923	regulation of RNA biosynthetic process
EQZ20_11025	COG1780	Probably involved in ribonucleotide reductase function
EQZ20_11030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQZ20_11035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQZ20_11040	COG4112	unkown
EQZ20_11045	COG1802	Transcriptional regulator
EQZ20_11050	COG0697	spore germination
EQZ20_11110	COG4282	regulation of fungal-type cell wall biogenesis
EQZ20_11115	COG4282	regulation of fungal-type cell wall biogenesis
EQZ20_11120	COG1073	alpha beta
EQZ20_11130	COG0464	growth
EQZ20_11135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EQZ20_11140	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EQZ20_11145	COG0789	Transcriptional regulator
EQZ20_11150	COG0174	glutamine synthetase
EQZ20_11170	COG0726	polysaccharide deacetylase
EQZ20_11220	COG2814	Major facilitator Superfamily
EQZ20_11230	COG0490	domain, Protein
EQZ20_11235	COG0475	glutathione-regulated potassium exporter activity
EQZ20_11260	COG0756	dUTP diphosphatase activity
EQZ20_11270	COG0194	GDP metabolic process
EQZ20_11300	COG1231	oxidoreductase activity
EQZ20_11305	COG1309	transcriptional regulator
EQZ20_11310	COG2076	Multidrug Resistance protein
EQZ20_11315	COG2076	Multidrug Resistance protein
EQZ20_11320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQZ20_11355	COG1309	transcriptional regulator
EQZ20_11370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EQZ20_11385	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_11390	COG2602	Beta-lactamase
EQZ20_11395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQZ20_11400	COG1388	LysM domain
EQZ20_11405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EQZ20_11410	COG4224	UPF0291 protein
EQZ20_11415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EQZ20_11425	COG3763	UPF0154 protein
EQZ20_11435	COG0785	Cytochrome C biogenesis protein
EQZ20_11440	COG2201	protein-glutamate methylesterase activity
EQZ20_11445	COG4846	Membrane protein involved in cytochrome C biogenesis
EQZ20_11455	COG0071	Belongs to the small heat shock protein (HSP20) family
EQZ20_11470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EQZ20_11475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_11495	COG0824	Thioesterase
EQZ20_11510	COG4841	protein insertion into membrane
EQZ20_11515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EQZ20_11520	COG1832	CoA-binding protein
EQZ20_11525	COG0187	DNA topoisomerase II activity
EQZ20_11530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQZ20_11535	COG1609	Transcriptional regulator
EQZ20_11550	COG2160	L-arabinose isomerase activity
EQZ20_11585	COG2181	nitrate reductase activity
EQZ20_11590	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EQZ20_11595	COG1140	nitrate reductase beta subunit
EQZ20_11600	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EQZ20_11620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQZ20_11630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQZ20_11635	COG2223	nitrite transmembrane transporter activity
EQZ20_11655	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EQZ20_11665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EQZ20_11675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQZ20_11685	COG3848	Pyruvate phosphate dikinase
EQZ20_11685	COG0574	Belongs to the PEP-utilizing enzyme family
EQZ20_11690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQZ20_11695	COG0798	PFAM Bile acid sodium symporter
EQZ20_11700	COG0640	Transcriptional regulator
EQZ20_11710	COG0693	protein deglycase activity
EQZ20_11730	COG1687	branched-chain amino acid
EQZ20_11735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EQZ20_11740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_11760	COG1024	Enoyl-CoA hydratase
EQZ20_11765	COG1012	belongs to the aldehyde dehydrogenase family
EQZ20_11770	COG2084	Dehydrogenase
EQZ20_11775	COG1960	acyl-CoA dehydrogenase activity
EQZ20_11780	COG0789	Transcriptional regulator
EQZ20_11790	COG1064	alcohol dehydrogenase
EQZ20_11795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQZ20_11800	COG2814	Major facilitator Superfamily
EQZ20_11805	COG1388	LysM domain
EQZ20_11810	COG2205	protein histidine kinase activity
EQZ20_11835	COG0667	Aldo Keto reductase
EQZ20_11840	COG1595	DNA-templated transcription, initiation
EQZ20_11845	COG1482	cell wall glycoprotein biosynthetic process
EQZ20_11850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQZ20_11850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQZ20_11850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_11855	COG3711	transcriptional antiterminator
EQZ20_11855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_11860	COG0785	Cytochrome C biogenesis protein
EQZ20_11890	COG1131	(ABC) transporter
EQZ20_11895	COG1725	Transcriptional regulator
EQZ20_11910	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQZ20_11935	COG2312	Erythromycin esterase
EQZ20_11940	COG1649	PFAM Uncharacterised BCR, COG1649
EQZ20_11945	COG2404	hydrolase activity, acting on ester bonds
EQZ20_11950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EQZ20_11955	COG1882	Formate acetyltransferase
EQZ20_11960	COG2027	D-alanyl-D-alanine carboxypeptidase
EQZ20_11965	COG1252	NADH dehydrogenase
EQZ20_11980	COG0166	Belongs to the GPI family
EQZ20_11990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQZ20_11995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EQZ20_12000	COG1024	Enoyl-CoA hydratase
EQZ20_12005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQZ20_12010	COG0511	ligase activity, forming carbon-carbon bonds
EQZ20_12015	COG0439	Biotin carboxylase
EQZ20_12020	COG0318	PFAM AMP-dependent synthetase and ligase
EQZ20_12025	COG1960	acyl-CoA dehydrogenase activity
EQZ20_12035	COG1733	regulation of RNA biosynthetic process
EQZ20_12040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EQZ20_12045	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EQZ20_12055	COG2323	membrane
EQZ20_12060	COG0175	sulfate reduction
EQZ20_12065	COG1809	phosphosulfolactate synthase activity
EQZ20_12070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ20_12075	COG4948	Mandelate Racemase Muconate Lactonizing
EQZ20_12080	COG2814	Major facilitator Superfamily
EQZ20_12085	COG0463	Glycosyl transferase, family 2
EQZ20_12100	COG0493	'glutamate synthase
EQZ20_12105	COG0070	glutamate synthase
EQZ20_12105	COG0069	glutamate synthase activity
EQZ20_12105	COG0067	glutamate synthase
EQZ20_12110	COG0583	DNA-binding transcription factor activity
EQZ20_12140	COG1132	(ABC) transporter
EQZ20_12145	COG3540	Alkaline phosphatase
EQZ20_12155	COG0300	oxidoreductase activity
EQZ20_12160	COG0477	Major facilitator Superfamily
EQZ20_12165	COG0243	molybdopterin cofactor binding
EQZ20_12175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQZ20_12180	COG1846	Transcriptional regulator
EQZ20_12185	COG2814	Major facilitator Superfamily
EQZ20_12195	COG0531	amino acid
EQZ20_12215	COG0697	spore germination
EQZ20_12240	COG2378	regulation of single-species biofilm formation
EQZ20_12250	COG0840	transmembrane signaling receptor activity
EQZ20_12255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ20_12260	COG1404	Belongs to the peptidase S8 family
EQZ20_12270	COG1309	transcriptional regulator
EQZ20_12280	COG1309	transcriptional regulator
EQZ20_12285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQZ20_12290	COG3708	Transcriptional regulator
EQZ20_12310	COG0640	Transcriptional regulator
EQZ20_12320	COG0531	amino acid
EQZ20_12325	COG0741	lytic transglycosylase activity
EQZ20_12330	COG1086	Polysaccharide biosynthesis protein
EQZ20_12350	COG2322	membrane
EQZ20_12360	COG1619	proteins homologs of microcin C7 resistance protein MccF
EQZ20_12370	COG1388	LysM domain
EQZ20_12380	COG3584	3D domain protein
EQZ20_12380	COG1388	LysM domain
EQZ20_12385	COG0514	ATP-dependent DNA helicase (RecQ)
EQZ20_12455	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_12460	COG1357	PFAM Pentapeptide repeats (8 copies)
EQZ20_12475	COG1280	lysine exporter protein (LysE YggA)
EQZ20_12480	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQZ20_12510	COG2318	DinB family
EQZ20_12515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EQZ20_12520	COG0602	queuosine metabolic process
EQZ20_12535	COG4555	ABC transporter
EQZ20_12545	COG2264	protein methyltransferase activity
EQZ20_12575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQZ20_12580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQZ20_12585	COG2140	Oxalate decarboxylase
EQZ20_12595	COG0071	Belongs to the small heat shock protein (HSP20) family
EQZ20_12615	COG3002	Belongs to the UPF0753 family
EQZ20_12620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQZ20_12625	COG5609	conserved protein (DUF2294)
EQZ20_12650	COG1012	belongs to the aldehyde dehydrogenase family
EQZ20_12665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EQZ20_12670	COG1846	Transcriptional regulator
EQZ20_12675	COG1657	PFAM Prenyltransferase squalene oxidase
EQZ20_12680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQZ20_12685	COG0733	neurotransmitter:sodium symporter activity
EQZ20_12690	COG0385	Bile acid
EQZ20_12695	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQZ20_12700	COG0567	Dehydrogenase, E1 component
EQZ20_12705	COG4548	von Willebrand factor, type A
EQZ20_12710	COG0714	Associated with various cellular activities
EQZ20_12715	COG2032	superoxide dismutase activity
EQZ20_12720	COG1388	LysM domain
EQZ20_12720	COG0791	NLP P60 protein
EQZ20_12725	COG0534	Mate efflux family protein
EQZ20_12730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQZ20_12735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQZ20_12745	COG2962	Rard protein
EQZ20_12755	COG4305	rare lipoprotein A
EQZ20_12765	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_12770	COG1733	regulation of RNA biosynthetic process
EQZ20_12775	COG0778	Nitroreductase
EQZ20_12780	COG0400	carboxylic ester hydrolase activity
EQZ20_12785	COG0346	lactoylglutathione lyase activity
EQZ20_12800	COG0793	Belongs to the peptidase S41A family
EQZ20_12800	COG3409	Peptidoglycan-binding domain 1 protein
EQZ20_12805	COG2226	methyltransferase
EQZ20_12815	COG1876	peptidase activity
EQZ20_12820	COG0813	purine-nucleoside phosphorylase activity
EQZ20_12825	COG0701	Predicted permease
EQZ20_12830	COG3689	TIGRFAM TIGR03943 family protein
EQZ20_12845	COG0671	phosphoesterase, PA-phosphatase related
EQZ20_12860	COG4479	Belongs to the UPF0346 family
EQZ20_12870	COG1509	lysine 2,3-aminomutase activity
EQZ20_12875	COG0456	acetyltransferase
EQZ20_12880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQZ20_12885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EQZ20_12890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EQZ20_12895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQZ20_12905	COG0456	acetyltransferase
EQZ20_12910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQZ20_12915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQZ20_12920	COG1846	Transcriptional regulator
EQZ20_12930	COG0534	Mate efflux family protein
EQZ20_12945	COG4698	Protein conserved in bacteria
EQZ20_12950	COG2755	lipolytic protein G-D-S-L family
EQZ20_12955	COG1999	signal sequence binding
EQZ20_12970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EQZ20_12975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EQZ20_12980	COG1272	protein, Hemolysin III
EQZ20_12985	COG0204	Acyl-transferase
EQZ20_12990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EQZ20_12995	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQZ20_13015	COG2521	methyltransferase
EQZ20_13015	COG2136	Putative SAM-dependent methyltransferase
EQZ20_13025	COG0129	dihydroxy-acid dehydratase activity
EQZ20_13030	COG1413	lyase activity
EQZ20_13035	COG1418	mRNA catabolic process
EQZ20_13040	COG0386	Belongs to the glutathione peroxidase family
EQZ20_13045	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EQZ20_13050	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EQZ20_13060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQZ20_13070	COG1278	Cold shock
EQZ20_13090	COG0328	RNA-DNA hybrid ribonuclease activity
EQZ20_13095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EQZ20_13100	COG0328	RNA-DNA hybrid ribonuclease activity
EQZ20_13110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ20_13120	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EQZ20_13135	COG1755	Isoprenylcysteine carboxyl methyltransferase
EQZ20_13140	COG3424	synthase
EQZ20_13150	COG2233	PERMEase
EQZ20_13155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQZ20_13165	COG1199	ATP-dependent helicase activity
EQZ20_13175	COG0116	Belongs to the methyltransferase superfamily
EQZ20_13185	COG3599	regulation of cell shape
EQZ20_13190	COG4474	Belongs to the UPF0398 family
EQZ20_13200	COG3359	exonuclease
EQZ20_13220	COG5002	protein histidine kinase activity
EQZ20_13220	COG3850	Histidine kinase
EQZ20_13225	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_13230	COG0583	DNA-binding transcription factor activity
EQZ20_13235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQZ20_13250	COG0577	efflux transmembrane transporter activity
EQZ20_13255	COG1136	(ABC) transporter
EQZ20_13275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQZ20_13280	COG0798	PFAM Bile acid sodium symporter
EQZ20_13285	COG0640	Transcriptional regulator
EQZ20_13295	COG2190	(PTS) system
EQZ20_13300	COG0071	Belongs to the small heat shock protein (HSP20) family
EQZ20_13335	COG3331	DNA recombination
EQZ20_13340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQZ20_13340	COG4499	WXG100 protein secretion system (Wss), protein YukC
EQZ20_13355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EQZ20_13360	COG3935	DnaD domain protein
EQZ20_13365	COG0017	Asparaginyl-tRNA synthetase
EQZ20_13370	COG0436	Aminotransferase
EQZ20_13375	COG5353	protein conserved in bacteria
EQZ20_13385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQZ20_13385	COG1199	ATP-dependent helicase activity
EQZ20_13390	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EQZ20_13395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EQZ20_13400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EQZ20_13410	COG0617	tRNA 3'-terminal CCA addition
EQZ20_13415	COG0438	transferase activity, transferring glycosyl groups
EQZ20_13420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQZ20_13425	COG1803	Methylglyoxal synthase
EQZ20_13430	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EQZ20_13435	COG1694	Mazg nucleotide pyrophosphohydrolase
EQZ20_13440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ20_13450	COG4347	Protein of unknown function (DUF1405)
EQZ20_13455	COG2010	Cytochrome c
EQZ20_13455	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EQZ20_13460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EQZ20_13465	COG0723	plastoquinol--plastocyanin reductase activity
EQZ20_13475	COG5582	Belongs to the UPF0302 family
EQZ20_13480	COG0457	Tetratricopeptide repeat
EQZ20_13485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EQZ20_13490	COG0287	Prephenate dehydrogenase
EQZ20_13495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EQZ20_13500	COG0159	tryptophan synthase activity
EQZ20_13505	COG0133	tryptophan synthase activity
EQZ20_13510	COG0135	phosphoribosylanthranilate isomerase activity
EQZ20_13515	COG0134	indole-3-glycerol-phosphate synthase activity
EQZ20_13520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQZ20_13525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQZ20_13530	COG4401	Chorismate mutase type I
EQZ20_13535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EQZ20_13540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EQZ20_13545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EQZ20_13550	COG0105	UTP biosynthetic process
EQZ20_13555	COG0142	geranyltranstransferase activity
EQZ20_13560	COG2226	methyltransferase
EQZ20_13565	COG0142	geranyltranstransferase activity
EQZ20_13580	COG0776	regulation of translation
EQZ20_13585	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EQZ20_13605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EQZ20_13610	COG1160	GTP binding
EQZ20_13635	COG1304	FMN binding
EQZ20_13640	COG0539	negative regulation of cytoplasmic translation
EQZ20_13645	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EQZ20_13650	COG2959	enzyme of heme biosynthesis
EQZ20_13655	COG3773	Cell wall hydrolase
EQZ20_13655	COG3409	Peptidoglycan-binding domain 1 protein
EQZ20_13660	COG2339	peptidase activity
EQZ20_13670	COG0492	ferredoxin-NADP+ reductase activity
EQZ20_13675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQZ20_13680	COG4862	establishment of competence for transformation
EQZ20_13685	COG1408	metallophosphoesterase
EQZ20_13695	COG1388	LysM domain
EQZ20_13700	COG1266	CAAX protease self-immunity
EQZ20_13705	COG0514	ATP-dependent DNA helicase (RecQ)
EQZ20_13710	COG4955	Helix-turn-helix domain
EQZ20_13715	COG1141	Ferredoxin
EQZ20_13720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EQZ20_13725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EQZ20_13730	COG0739	heme binding
EQZ20_13740	COG1595	DNA-templated transcription, initiation
EQZ20_13750	COG5002	protein histidine kinase activity
EQZ20_13755	COG0745	RESPONSE REGULATOR receiver
EQZ20_13760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQZ20_13765	COG1333	cytochrome c biogenesis protein
EQZ20_13770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_13775	COG1187	pseudouridine synthase activity
EQZ20_13780	COG0700	Nucleoside recognition
EQZ20_13785	COG2715	membrane protein required for spore maturation
EQZ20_13790	COG1686	Belongs to the peptidase S11 family
EQZ20_13800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EQZ20_13805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EQZ20_13810	COG1547	Domain of unknown function (DUF309)
EQZ20_13815	COG0456	acetyltransferase
EQZ20_13820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EQZ20_13825	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQZ20_13825	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQZ20_13830	COG0307	riboflavin synthase, alpha
EQZ20_13835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQZ20_13835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQZ20_13855	COG2801	Transposase and inactivated derivatives
EQZ20_13870	COG0457	Tetratricopeptide repeat
EQZ20_13875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EQZ20_13880	COG4086	secreted protein
EQZ20_13885	COG4195	phage-related replication protein
EQZ20_13890	COG5002	protein histidine kinase activity
EQZ20_13905	COG0019	diaminopimelate decarboxylase activity
EQZ20_13915	COG0697	spore germination
EQZ20_13930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQZ20_13965	COG1686	Belongs to the peptidase S11 family
EQZ20_13970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EQZ20_13975	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EQZ20_13980	COG4974	Belongs to the 'phage' integrase family
EQZ20_13990	COG0735	belongs to the Fur family
EQZ20_13995	COG1300	Membrane
EQZ20_14000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ20_14010	COG1953	Uracil, thiamine, allantoin
EQZ20_14025	COG2153	protein acetylation
EQZ20_14030	COG1379	DNA repair
EQZ20_14035	COG0494	nUDIX hydrolase
EQZ20_14045	COG1309	transcriptional regulator
EQZ20_14055	COG0667	Aldo Keto reductase
EQZ20_14060	COG0477	Major facilitator Superfamily
EQZ20_14065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_14070	COG3420	alginic acid biosynthetic process
EQZ20_14080	COG1073	alpha beta
EQZ20_14090	COG4918	Iron-sulphur cluster biosynthesis
EQZ20_14105	COG0456	acetyltransferase
EQZ20_14135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQZ20_14160	COG0346	lactoylglutathione lyase activity
EQZ20_14165	COG1072	(Pantothenic acid kinase))
EQZ20_14200	COG2205	protein histidine kinase activity
EQZ20_14205	COG0745	RESPONSE REGULATOR receiver
EQZ20_14225	COG2814	Major facilitator Superfamily
EQZ20_14235	COG4195	phage-related replication protein
EQZ20_14240	COG0300	oxidoreductase activity
EQZ20_14245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQZ20_14250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQZ20_14260	COG4187	Peptidase family M20/M25/M40
EQZ20_14265	COG1902	pentaerythritol trinitrate reductase activity
EQZ20_14270	COG0596	Alpha beta hydrolase
EQZ20_14280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQZ20_14285	COG1234	tRNA 3'-trailer cleavage
EQZ20_14290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EQZ20_14295	COG2188	Transcriptional regulator
EQZ20_14300	COG2723	6-phospho-beta-galactosidase activity
EQZ20_14305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ20_14315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ20_14325	COG1785	Belongs to the alkaline phosphatase family
EQZ20_14330	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_14335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EQZ20_14340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQZ20_14350	COG0706	membrane insertase activity
EQZ20_14360	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQZ20_14365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EQZ20_14375	COG4129	membrane
EQZ20_14380	COG1126	abc transporter atp-binding protein
EQZ20_14385	COG0765	amino acid transport
EQZ20_14390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ20_14405	COG1597	lipid kinase activity
EQZ20_14415	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQZ20_14420	COG0022	dehydrogenase e1 component
EQZ20_14425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQZ20_14430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQZ20_14435	COG3426	butyrate kinase activity
EQZ20_14445	COG0280	phosphate acetyltransferase
EQZ20_14450	COG3290	protein histidine kinase activity
EQZ20_14450	COG3829	transcription factor binding
EQZ20_14460	COG0584	glycerophosphoryl diester phosphodiesterase
EQZ20_14465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EQZ20_14470	COG0745	RESPONSE REGULATOR receiver
EQZ20_14475	COG0750	zinc metalloprotease
EQZ20_14480	COG0497	DNA recombination
EQZ20_14485	COG1438	arginine binding
EQZ20_14490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EQZ20_14495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EQZ20_14500	COG0142	geranyltranstransferase activity
EQZ20_14505	COG1722	exodeoxyribonuclease VII activity
EQZ20_14510	COG1570	exodeoxyribonuclease VII activity
EQZ20_14515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EQZ20_14520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQZ20_14525	COG1302	Protein conserved in bacteria
EQZ20_14530	COG0439	Biotin carboxylase
EQZ20_14535	COG0511	ligase activity, forming carbon-carbon bonds
EQZ20_14575	COG3854	ATPases associated with a variety of cellular activities
EQZ20_14585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EQZ20_14590	COG0006	proline dipeptidase activity
EQZ20_14595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EQZ20_14605	COG3872	metal-dependent enzyme
EQZ20_14615	COG1752	Esterase of the alpha-beta hydrolase superfamily
EQZ20_14625	COG1321	iron dependent repressor
EQZ20_14635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQZ20_14645	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQZ20_14650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQZ20_14655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EQZ20_14660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EQZ20_14685	COG0681	Belongs to the peptidase S26 family
EQZ20_14710	COG4940	Competence protein ComGF
EQZ20_14720	COG4970	Tfp pilus assembly protein FimT
EQZ20_14725	COG4537	Required for transformation and DNA binding
EQZ20_14730	COG1459	type II secretion system
EQZ20_14735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EQZ20_14740	COG1366	Belongs to the anti-sigma-factor antagonist family
EQZ20_14750	COG1393	Belongs to the ArsC family
EQZ20_14760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQZ20_14770	COG0011	TIGRFAM Protein of
EQZ20_14780	COG2866	Carboxypeptidase
EQZ20_14785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQZ20_14795	COG2116	formate transmembrane transporter activity
EQZ20_14805	COG1368	sulfuric ester hydrolase activity
EQZ20_14810	COG1940	carbohydrate kinase activity
EQZ20_14815	COG4483	Protein conserved in bacteria
EQZ20_14820	COG0697	spore germination
EQZ20_14825	COG0705	Rhomboid family
EQZ20_14825	COG0457	Tetratricopeptide repeat
EQZ20_14830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EQZ20_14835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQZ20_14845	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQZ20_14850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQZ20_14855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQZ20_14860	COG0581	inorganic phosphate transmembrane transporter activity
EQZ20_14865	COG0573	inorganic phosphate transmembrane transporter activity
EQZ20_14870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQZ20_14880	COG0477	Major facilitator Superfamily
EQZ20_14885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQZ20_14890	COG2839	Protein conserved in bacteria
EQZ20_14895	COG5521	maltodextrose utilization protein MalA
EQZ20_14900	COG1388	LysM domain
EQZ20_14905	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EQZ20_14910	COG4709	membrane
EQZ20_14915	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EQZ20_14920	COG0735	belongs to the Fur family
EQZ20_14925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQZ20_14930	COG1121	(ABC) transporter
EQZ20_14935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ20_14945	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EQZ20_14950	COG0513	Belongs to the DEAD box helicase family
EQZ20_14960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EQZ20_14965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EQZ20_14970	COG2384	SAM-dependent methyltransferase
EQZ20_15000	COG2010	Cytochrome c
EQZ20_15005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQZ20_15010	COG0358	DNA primase activity
EQZ20_15015	COG1671	Belongs to the UPF0178 family
EQZ20_15020	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EQZ20_15025	COG0517	IMP dehydrogenase activity
EQZ20_15030	COG0751	glycine-tRNA ligase activity
EQZ20_15035	COG0752	glycyl-tRNA synthetase alpha subunit
EQZ20_15040	COG1381	Involved in DNA repair and RecF pathway recombination
EQZ20_15050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EQZ20_15055	COG0295	cytidine deaminase activity
EQZ20_15060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EQZ20_15065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EQZ20_15070	COG1480	7TM receptor with intracellular HD hydrolase
EQZ20_15075	COG1702	phosphate starvation-inducible protein PhoH
EQZ20_15080	COG0561	phosphatase activity
EQZ20_15095	COG4864	UPF0365 protein
EQZ20_15100	COG1030	water channel activity
EQZ20_15105	COG1610	YqeY-like protein
EQZ20_15110	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EQZ20_15115	COG1283	sodium-dependent phosphate transmembrane transporter activity
EQZ20_15120	COG1247	-acetyltransferase
EQZ20_15130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQZ20_15135	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EQZ20_15140	COG2264	protein methyltransferase activity
EQZ20_15145	COG0484	heat shock protein binding
EQZ20_15150	COG0443	Heat shock 70 kDa protein
EQZ20_15155	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EQZ20_15160	COG1420	regulation of RNA biosynthetic process
EQZ20_15165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQZ20_15170	COG0481	GTPase activity
EQZ20_15180	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQZ20_15185	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EQZ20_15190	COG0268	Binds directly to 16S ribosomal RNA
EQZ20_15195	COG1466	dna polymerase III delta subunit
EQZ20_15205	COG2333	competence protein COMEC
EQZ20_15205	COG0658	competence protein
EQZ20_15210	COG2131	deaminase
EQZ20_15215	COG1555	photosystem II stabilization
EQZ20_15215	COG1596	polysaccharide export
EQZ20_15220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQZ20_15225	COG2226	methyltransferase
EQZ20_15230	COG0799	negative regulation of ribosome biogenesis
EQZ20_15235	COG1713	HD superfamily hydrolase involved in NAD metabolism
EQZ20_15240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EQZ20_15245	COG1534	Rna-binding protein
EQZ20_15250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQZ20_15255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQZ20_15260	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EQZ20_15270	COG2755	lipolytic protein G-D-S-L family
EQZ20_15280	COG5609	conserved protein (DUF2294)
EQZ20_15285	COG3383	formate dehydrogenase (NAD+) activity
EQZ20_15290	COG2427	Protein of unknown function (DUF1641)
EQZ20_15300	COG1902	pentaerythritol trinitrate reductase activity
EQZ20_15320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_15325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQZ20_15330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQZ20_15335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQZ20_15350	COG0583	DNA-binding transcription factor activity
EQZ20_15395	COG0697	spore germination
EQZ20_15405	COG0583	DNA-binding transcription factor activity
EQZ20_15410	COG2070	2-Nitropropane dioxygenase
EQZ20_15420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EQZ20_15425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EQZ20_15430	COG0604	alcohol dehydrogenase
EQZ20_15435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQZ20_15460	COG2132	Multicopper oxidase
EQZ20_15465	COG5002	protein histidine kinase activity
EQZ20_15470	COG0745	RESPONSE REGULATOR receiver
EQZ20_15475	COG1388	LysM domain
EQZ20_15485	COG2409	Drug exporters of the RND superfamily
EQZ20_15490	COG2197	response regulator
EQZ20_15495	COG4585	Histidine kinase
EQZ20_15500	COG2124	cytochrome p450
EQZ20_15550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EQZ20_15555	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQZ20_15560	COG1733	regulation of RNA biosynthetic process
EQZ20_15575	COG2197	response regulator
EQZ20_15580	COG4585	Histidine kinase
EQZ20_15585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_15590	COG0730	response to heat
EQZ20_15595	COG0425	Belongs to the sulfur carrier protein TusA family
EQZ20_15600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQZ20_15600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQZ20_15605	COG2210	Belongs to the sulfur carrier protein TusA family
EQZ20_15610	COG0425	Belongs to the sulfur carrier protein TusA family
EQZ20_15610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQZ20_15615	COG2210	Belongs to the sulfur carrier protein TusA family
EQZ20_15620	COG1937	Protein conserved in bacteria
EQZ20_15640	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EQZ20_15645	COG1522	sequence-specific DNA binding
EQZ20_15675	COG1486	melibiose metabolic process
EQZ20_15680	COG0561	phosphatase activity
EQZ20_15685	COG0492	ferredoxin-NADP+ reductase activity
EQZ20_15695	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_15705	COG1942	4-Oxalocrotonate Tautomerase
EQZ20_15710	COG3443	Belongs to the bacterial solute-binding protein 9 family
EQZ20_15720	COG2124	cytochrome p450
EQZ20_15725	COG2368	4-hydroxyphenylacetate
EQZ20_15735	COG0833	amino acid
EQZ20_15740	COG4187	Peptidase family M20/M25/M40
EQZ20_15745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQZ20_15760	COG5583	Uncharacterized small protein (DUF2292)
EQZ20_15770	COG3507	Belongs to the glycosyl hydrolase 43 family
EQZ20_15775	COG2211	Major facilitator Superfamily
EQZ20_15780	COG1917	Cupin 2, conserved barrel domain protein
EQZ20_15780	COG4977	sequence-specific DNA binding
EQZ20_15785	COG1082	Xylose isomerase domain protein TIM barrel
EQZ20_15790	COG0673	inositol 2-dehydrogenase activity
EQZ20_15795	COG1621	beta-fructofuranosidase activity
EQZ20_15800	COG3716	PTS system mannose fructose sorbose family IID component
EQZ20_15805	COG3715	PTS system
EQZ20_15810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_15815	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_15820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EQZ20_15820	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EQZ20_15825	COG1113	amino acid transport
EQZ20_15840	COG1525	nuclease
EQZ20_15850	COG2814	Major facilitator Superfamily
EQZ20_15860	COG2350	Protein conserved in bacteria
EQZ20_15870	COG2169	Transcriptional regulator
EQZ20_15880	COG0656	L-ascorbic acid biosynthetic process
EQZ20_15885	COG2814	Major facilitator Superfamily
EQZ20_15890	COG1733	regulation of RNA biosynthetic process
EQZ20_15895	COG1587	Uroporphyrinogen-III synthase
EQZ20_15905	COG0583	DNA-binding transcription factor activity
EQZ20_15910	COG2814	Major facilitator Superfamily
EQZ20_15920	COG2124	cytochrome p450
EQZ20_15920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQZ20_15925	COG1309	transcriptional regulator
EQZ20_15935	COG1404	Belongs to the peptidase S8 family
EQZ20_15940	COG2226	methyltransferase
EQZ20_15965	COG0626	cystathionine gamma-synthase activity
EQZ20_15970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQZ20_15975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EQZ20_15980	COG2226	methyltransferase
EQZ20_15995	COG0768	penicillin binding
EQZ20_16000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQZ20_16005	COG0572	uridine kinase
EQZ20_16025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQZ20_16035	COG3906	Belongs to the UPF0473 family
EQZ20_16040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EQZ20_16045	COG4472	Bacterial protein of unknown function (DUF965)
EQZ20_16050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EQZ20_16055	COG0628	permease
EQZ20_16060	COG1126	abc transporter atp-binding protein
EQZ20_16065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ20_16070	COG0765	amino acid transport
EQZ20_16075	COG0765	amino acid transport
EQZ20_16090	COG3881	PFAM PRC-barrel domain
EQZ20_16095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQZ20_16100	COG0457	Tetratricopeptide repeat
EQZ20_16105	COG0482	sulfurtransferase activity
EQZ20_16110	COG1104	cysteine desulfurase activity
EQZ20_16115	COG1959	2 iron, 2 sulfur cluster binding
EQZ20_16120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EQZ20_16130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EQZ20_16140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EQZ20_16145	COG0124	histidyl-tRNA synthetase
EQZ20_16150	COG4991	sh3 domain protein
EQZ20_16150	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQZ20_16150	COG3103	Sh3 type 3 domain protein
EQZ20_16155	COG1490	D-aminoacyl-tRNA deacylase activity
EQZ20_16160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EQZ20_16165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQZ20_16170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQZ20_16170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EQZ20_16175	COG5416	Lipopolysaccharide assembly protein A domain
EQZ20_16180	COG0490	domain, Protein
EQZ20_16185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQZ20_16185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQZ20_16195	COG2244	polysaccharide biosynthetic process
EQZ20_16200	COG2323	membrane
EQZ20_16210	COG1862	Preprotein translocase
EQZ20_16215	COG0343	queuine tRNA-ribosyltransferase activity
EQZ20_16220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EQZ20_16230	COG2255	four-way junction helicase activity
EQZ20_16235	COG0632	four-way junction helicase activity
EQZ20_16245	COG2112	serine threonine protein kinase
EQZ20_16255	COG2318	DinB family
EQZ20_16260	COG4195	phage-related replication protein
EQZ20_16280	COG0217	transcriptional regulatory protein
EQZ20_16290	COG1388	LysM domain
EQZ20_16295	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EQZ20_16300	COG0157	Belongs to the NadC ModD family
EQZ20_16305	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EQZ20_16310	COG1104	cysteine desulfurase activity
EQZ20_16315	COG1827	regulation of RNA biosynthetic process
EQZ20_16320	COG0077	Prephenate dehydratase
EQZ20_16325	COG4492	Belongs to the UPF0735 family
EQZ20_16330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EQZ20_16335	COG3290	protein histidine kinase activity
EQZ20_16340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EQZ20_16345	COG2868	ribosomal protein
EQZ20_16350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EQZ20_16355	COG1994	Peptidase M50
EQZ20_16360	COG0739	heme binding
EQZ20_16365	COG3832	glyoxalase III activity
EQZ20_16370	COG0640	Transcriptional regulator
EQZ20_16375	COG2894	cell division
EQZ20_16380	COG0850	regulation of cytokinetic process
EQZ20_16385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EQZ20_16390	COG1792	Involved in formation and maintenance of cell shape
EQZ20_16395	COG1077	Cell shape determining protein MreB Mrl
EQZ20_16400	COG2003	Belongs to the UPF0758 family
EQZ20_16405	COG0424	maF-like protein
EQZ20_16415	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EQZ20_16420	COG0285	dihydrofolate synthase activity
EQZ20_16425	COG0525	valine-tRNA ligase activity
EQZ20_16435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EQZ20_16440	COG1388	LysM domain
EQZ20_16445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQZ20_16450	COG0113	porphobilinogen synthase activity
EQZ20_16455	COG1587	Uroporphyrinogen-III synthase
EQZ20_16460	COG0181	hydroxymethylbilane synthase activity
EQZ20_16465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQZ20_16470	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EQZ20_16480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EQZ20_16485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EQZ20_16490	COG1067	ATP-dependent peptidase activity
EQZ20_16490	COG0470	DNA polymerase III
EQZ20_16495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EQZ20_16500	COG0544	peptidyl-prolyl cis-trans isomerase activity
EQZ20_16505	COG0457	Tetratricopeptide repeat
EQZ20_16505	COG1477	protein flavinylation
EQZ20_16510	COG0066	3-isopropylmalate dehydratase activity
EQZ20_16515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EQZ20_16520	COG0473	3-isopropylmalate dehydrogenase activity
EQZ20_16525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQZ20_16530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EQZ20_16535	COG0440	acetolactate synthase activity
EQZ20_16540	COG0028	Belongs to the TPP enzyme family
EQZ20_16545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQZ20_16555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQZ20_16585	COG0622	Phosphoesterase
EQZ20_16590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EQZ20_16595	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EQZ20_16600	COG5401	PFAM Sporulation and spore germination
EQZ20_16605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EQZ20_16610	COG1846	Transcriptional regulator
EQZ20_16615	COG2197	response regulator
EQZ20_16620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EQZ20_16770	COG1783	phage Terminase large subunit
EQZ20_16775	COG5484	DNA packaging
EQZ20_16780	COG3677	Transposase
EQZ20_16855	COG3723	Recombinational DNA repair protein, rece pathway
EQZ20_16860	COG5377	YqaJ viral recombinase family
EQZ20_16900	COG3620	sequence-specific DNA binding
EQZ20_16915	COG2856	Zn peptidase
EQZ20_16920	COG2197	response regulator
EQZ20_16935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EQZ20_16940	COG1053	succinate dehydrogenase
EQZ20_16945	COG2009	succinate dehydrogenase
EQZ20_16950	COG1719	4-vinyl reductase, 4VR
EQZ20_16960	COG0527	aspartate kinase activity
EQZ20_16970	COG0322	excinuclease ABC activity
EQZ20_16975	COG3118	belongs to the thioredoxin family
EQZ20_16980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EQZ20_16985	COG2086	electron transfer activity
EQZ20_16990	COG1024	Enoyl-CoA hydratase
EQZ20_16995	COG1309	transcriptional regulator
EQZ20_17000	COG0318	PFAM AMP-dependent synthetase and ligase
EQZ20_17005	COG3766	membrane
EQZ20_17010	COG1193	negative regulation of DNA recombination
EQZ20_17015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EQZ20_17015	COG1796	DNA polymerase
EQZ20_17020	COG1286	toxin biosynthetic process
EQZ20_17025	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EQZ20_17030	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQZ20_17045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ20_17045	COG0072	phenylalanine-tRNA ligase activity
EQZ20_17050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EQZ20_17055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQZ20_17065	COG1966	Carbon starvation protein
EQZ20_17070	COG1309	transcriptional regulator
EQZ20_17080	COG3428	Bacterial PH domain
EQZ20_17100	COG0395	ABC-type sugar transport system, permease component
EQZ20_17105	COG1175	transmembrane transport
EQZ20_17110	COG1653	transport
EQZ20_17115	COG0371	Dehydrogenase
EQZ20_17120	COG0235	Class ii aldolase
EQZ20_17125	COG1069	ribulokinase activity
EQZ20_17130	COG2160	L-arabinose isomerase activity
EQZ20_17135	COG3507	Belongs to the glycosyl hydrolase 43 family
EQZ20_17140	COG1363	Peptidase, m42
EQZ20_17150	COG3326	Membrane
EQZ20_17155	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EQZ20_17165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EQZ20_17170	COG1346	cytolysis
EQZ20_17180	COG3540	Alkaline phosphatase
EQZ20_17185	COG3279	Response regulator of the LytR AlgR family
EQZ20_17190	COG3275	phosphorelay sensor kinase activity
EQZ20_17220	COG1484	DNA-dependent DNA replication
EQZ20_17225	COG3611	Membrane attachment protein
EQZ20_17230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EQZ20_17240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EQZ20_17245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQZ20_17250	COG0237	dephospho-CoA kinase activity
EQZ20_17255	COG1971	Probably functions as a manganese efflux pump
EQZ20_17260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EQZ20_17265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ20_17265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ20_17270	COG5002	protein histidine kinase activity
EQZ20_17275	COG0745	RESPONSE REGULATOR receiver
EQZ20_17280	COG0039	L-malate dehydrogenase activity
EQZ20_17285	COG0538	isocitrate dehydrogenase activity
EQZ20_17290	COG0372	Belongs to the citrate synthase family
EQZ20_17295	COG2707	UPF0756 membrane protein
EQZ20_17300	COG0628	permease
EQZ20_17305	COG3030	protein affecting phage T7 exclusion by the F plasmid
EQZ20_17315	COG0205	6-phosphofructokinase activity
EQZ20_17320	COG0825	malonyl-CoA metabolic process
EQZ20_17325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EQZ20_17330	COG0281	malic enzyme
EQZ20_17335	COG0587	DNA-directed DNA polymerase activity
EQZ20_17355	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EQZ20_17365	COG4109	DRTGG domain
EQZ20_17370	COG1695	Transcriptional regulator
EQZ20_17375	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EQZ20_17380	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_17385	COG0165	Argininosuccinate lyase
EQZ20_17390	COG0137	argininosuccinate synthase activity
EQZ20_17395	COG0521	Mo-molybdopterin cofactor biosynthetic process
EQZ20_17400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EQZ20_17405	COG0827	DNA restriction-modification system
EQZ20_17410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EQZ20_17415	COG3874	Sporulation protein YtfJ
EQZ20_17430	COG1714	RDD family
EQZ20_17435	COG0616	signal peptide processing
EQZ20_17440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQZ20_17450	COG0477	Major facilitator Superfamily
EQZ20_17455	COG1846	Transcriptional regulator
EQZ20_17460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQZ20_17470	COG0301	tRNA thio-modification
EQZ20_17475	COG1104	cysteine desulfurase activity
EQZ20_17480	COG1114	Component of the transport system for branched-chain amino acids
EQZ20_17485	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EQZ20_17490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EQZ20_17495	COG1309	transcriptional regulator
EQZ20_17500	COG1956	GAF domain-containing protein
EQZ20_17505	COG2199	diguanylate cyclase activity
EQZ20_17505	COG2203	Gaf domain
EQZ20_17510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EQZ20_17525	COG2323	membrane
EQZ20_17530	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EQZ20_17535	COG0662	Cupin 2, conserved barrel domain protein
EQZ20_17545	COG4824	toxin secretion phage lysis holin
EQZ20_17570	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_17575	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQZ20_17595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EQZ20_17600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQZ20_17605	COG0454	-acetyltransferase
EQZ20_17610	COG0517	IMP dehydrogenase activity
EQZ20_17615	COG0123	including yeast histone deacetylase and acetoin utilization protein
EQZ20_17625	COG1360	Flagellar Motor Protein
EQZ20_17630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EQZ20_17635	COG1609	Transcriptional regulator
EQZ20_17640	COG1605	Chorismate mutase
EQZ20_17640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EQZ20_17645	COG3118	belongs to the thioredoxin family
EQZ20_17655	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EQZ20_17660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EQZ20_17665	COG1674	ftsk spoiiie
EQZ20_17670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ20_17675	COG4848	Belongs to the UPF0354 family
EQZ20_17680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_17690	COG1363	Peptidase, m42
EQZ20_17695	COG5584	Small secreted protein
EQZ20_17700	COG0281	malic enzyme
EQZ20_17705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQZ20_17710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EQZ20_17720	COG0510	thiamine kinase activity
EQZ20_17725	COG1597	lipid kinase activity
EQZ20_17735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQZ20_17740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQZ20_17750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQZ20_17755	COG2252	PERMEase
EQZ20_17760	COG1349	DNA-binding transcription factor activity
EQZ20_17765	COG1187	pseudouridine synthase activity
EQZ20_17770	COG2244	polysaccharide biosynthetic process
EQZ20_17775	COG2081	HI0933 family
EQZ20_17785	COG1349	DNA-binding transcription factor activity
EQZ20_17790	COG3395	kinase activity
EQZ20_17795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EQZ20_17810	COG0471	metal ion transport
EQZ20_17815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQZ20_17830	COG5578	integral membrane protein
EQZ20_17835	COG0673	inositol 2-dehydrogenase activity
EQZ20_17840	COG1653	transport
EQZ20_17845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EQZ20_17850	COG4209	transmembrane transport
EQZ20_17855	COG2207	Transcriptional regulator
EQZ20_17860	COG1653	transport
EQZ20_17865	COG0395	ABC-type sugar transport system, permease component
EQZ20_17875	COG1073	alpha beta
EQZ20_17885	COG0583	DNA-binding transcription factor activity
EQZ20_17890	COG0346	lactoylglutathione lyase activity
EQZ20_17895	COG0495	leucyl-tRNA aminoacylation
EQZ20_17905	COG2814	Major facilitator Superfamily
EQZ20_17920	COG2433	Pfam Transposase IS66
EQZ20_17925	COG0577	efflux transmembrane transporter activity
EQZ20_17930	COG1136	(ABC) transporter
EQZ20_17940	COG1131	(ABC) transporter
EQZ20_17945	COG1725	Transcriptional regulator
EQZ20_17955	COG1242	4 iron, 4 sulfur cluster binding
EQZ20_17960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EQZ20_17965	COG1301	dicarboxylic acid transport
EQZ20_17975	COG2267	carboxylic ester hydrolase activity
EQZ20_17980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EQZ20_17985	COG0671	phosphoesterase, PA-phosphatase related
EQZ20_18005	COG0367	asparagine synthase
EQZ20_18010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EQZ20_18015	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EQZ20_18025	COG1506	peptidase
EQZ20_18030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQZ20_18035	COG1116	anion transmembrane transporter activity
EQZ20_18040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQZ20_18045	COG0494	nUDIX hydrolase
EQZ20_18060	COG4824	toxin secretion phage lysis holin
EQZ20_18065	COG0783	Belongs to the Dps family
EQZ20_18080	COG1854	S-ribosylhomocysteine lyase activity
EQZ20_18085	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EQZ20_18090	COG0288	reversible hydration of carbon dioxide
EQZ20_18095	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQZ20_18100	COG0254	rRNA binding
EQZ20_18105	COG1271	oxidase subunit
EQZ20_18110	COG1294	oxidase, subunit
EQZ20_18130	COG2079	MmgE PrpD family protein
EQZ20_18140	COG1126	abc transporter atp-binding protein
EQZ20_18145	COG0765	amino acid transport
EQZ20_18150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ20_18165	COG4948	Mandelate Racemase Muconate Lactonizing
EQZ20_18170	COG0318	PFAM AMP-dependent synthetase and ligase
EQZ20_18175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EQZ20_18180	COG0596	Alpha beta hydrolase
EQZ20_18185	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EQZ20_18190	COG1169	isochorismate synthase
EQZ20_18195	COG1575	Belongs to the MenA family. Type 1 subfamily
EQZ20_18200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQZ20_18345	COG1609	Transcriptional regulator
EQZ20_18350	COG3859	Proton-coupled thiamine transporter YuaJ
EQZ20_18355	COG3764	Sortase (surface protein transpeptidase)
EQZ20_18370	COG0457	Tetratricopeptide repeat
EQZ20_18375	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EQZ20_18380	COG2318	DinB family
EQZ20_18390	COG1454	alcohol dehydrogenase
EQZ20_18400	COG1510	regulation of RNA biosynthetic process
EQZ20_18405	COG1017	nitric oxide dioxygenase activity
EQZ20_18405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQZ20_18410	COG0586	Pfam SNARE associated Golgi protein
EQZ20_18500	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EQZ20_18510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQZ20_18515	COG0726	polysaccharide deacetylase
EQZ20_18520	COG1408	metallophosphoesterase
EQZ20_18525	COG1968	undecaprenyl-diphosphatase activity
EQZ20_18530	COG0628	permease
EQZ20_18535	COG0673	inositol 2-dehydrogenase activity
EQZ20_18545	COG0840	transmembrane signaling receptor activity
EQZ20_18550	COG0840	transmembrane signaling receptor activity
EQZ20_18555	COG0840	transmembrane signaling receptor activity
EQZ20_18570	COG0432	Pfam Uncharacterised protein family UPF0047
EQZ20_18575	COG0366	Alpha amylase catalytic
EQZ20_18580	COG5297	Belongs to the glycosyl hydrolase family 6
EQZ20_18585	COG1253	flavin adenine dinucleotide binding
EQZ20_18590	COG2738	Putative neutral zinc metallopeptidase
EQZ20_18605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EQZ20_18615	COG2323	membrane
EQZ20_18620	COG0166	Belongs to the GPI family
EQZ20_18625	COG1979	alcohol dehydrogenase
EQZ20_18630	COG2155	Conserved Protein
EQZ20_18635	COG1098	S1 RNA binding domain
EQZ20_18640	COG0436	Aminotransferase
EQZ20_18645	COG1522	sequence-specific DNA binding
EQZ20_18650	COG2267	carboxylic ester hydrolase activity
EQZ20_18660	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EQZ20_18675	COG5018	Exonuclease
EQZ20_18680	COG2814	Major facilitator Superfamily
EQZ20_18685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQZ20_18690	COG3011	Protein conserved in bacteria
EQZ20_18705	COG3290	protein histidine kinase activity
EQZ20_18710	COG4565	transcriptional regulatory protein
EQZ20_18735	COG1183	phosphatidylcholine synthase activity
EQZ20_18740	COG0586	Pfam SNARE associated Golgi protein
EQZ20_18745	COG0688	phosphatidylethanolamine metabolic process
EQZ20_18750	COG3493	citrate carrier protein
EQZ20_18760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQZ20_18760	COG2111	Na H antiporter
EQZ20_18765	COG2111	Na H antiporter
EQZ20_18770	COG1006	Multisubunit Na H antiporter MnhC subunit
EQZ20_18775	COG0651	ATP synthesis coupled electron transport
EQZ20_18780	COG1863	multisubunit Na H antiporter MnhE subunit
EQZ20_18785	COG2212	antiporter activity
EQZ20_18790	COG1320	monovalent cation:proton antiporter activity
EQZ20_18795	COG2050	protein possibly involved in aromatic compounds catabolism
EQZ20_18800	COG2197	response regulator
EQZ20_18805	COG4585	Histidine kinase
EQZ20_18815	COG0142	geranyltranstransferase activity
EQZ20_18830	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EQZ20_18835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EQZ20_18840	COG1335	isochorismatase
EQZ20_18845	COG5506	Protein of unknown function (DUF1694)
EQZ20_18860	COG0628	permease
EQZ20_18865	COG1959	2 iron, 2 sulfur cluster binding
EQZ20_18880	COG1418	mRNA catabolic process
EQZ20_18885	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_18900	COG1511	domain protein
EQZ20_18905	COG1674	ftsk spoiiie
EQZ20_18905	COG0433	COG0433 Predicted ATPase
EQZ20_18910	COG4499	WXG100 protein secretion system (Wss), protein YukC
EQZ20_18915	COG5417	Belongs to the EsaB family
EQZ20_18920	COG4842	Belongs to the WXG100 family
EQZ20_18925	COG2508	Transcriptional regulator
EQZ20_18925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EQZ20_18930	COG0686	Belongs to the AlaDH PNT family
EQZ20_18935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EQZ20_18940	COG1268	BioY protein
EQZ20_18945	COG2056	Na+-H+ antiporter family
EQZ20_18955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EQZ20_18960	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EQZ20_18965	COG3584	3D domain protein
EQZ20_18975	COG1252	NADH dehydrogenase
EQZ20_18980	COG0492	ferredoxin-NADP+ reductase activity
EQZ20_19000	COG0316	Belongs to the HesB IscA family
EQZ20_19005	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EQZ20_19010	COG4844	belongs to the
EQZ20_19015	COG1252	NADH dehydrogenase
EQZ20_19030	COG0457	Tetratricopeptide repeat
EQZ20_19035	COG3479	Phenolic acid decarboxylase
EQZ20_19045	COG4837	Protein of unknown function (DUF1462)
EQZ20_19050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EQZ20_19055	COG1506	peptidase
EQZ20_19055	COG0823	Involved in the tonB-independent uptake of proteins
EQZ20_19055	COG4946	Tricorn protease homolog
EQZ20_19060	COG0083	homoserine kinase activity
EQZ20_19065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EQZ20_19070	COG0460	homoserine dehydrogenase
EQZ20_19075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQZ20_19080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EQZ20_19085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQZ20_19090	COG0647	UMP catabolic process
EQZ20_19095	COG2445	Protein of unknown function DUF86
EQZ20_19100	COG4470	Protein conserved in bacteria
EQZ20_19115	COG0739	heme binding
EQZ20_19125	COG3377	Domain of unknown function (DUF1805)
EQZ20_19130	COG0737	Belongs to the 5'-nucleotidase family
EQZ20_19135	COG0730	response to heat
EQZ20_19140	COG1801	Protein of unknown function DUF72
EQZ20_19150	COG3226	Transcriptional regulator
EQZ20_19160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EQZ20_19165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQZ20_19170	COG2508	Transcriptional regulator
EQZ20_19180	COG2814	Major facilitator Superfamily
EQZ20_19185	COG1288	antiporter activity
EQZ20_19195	COG2356	endonuclease I
EQZ20_19200	COG3842	ATPase activity
EQZ20_19205	COG2188	Transcriptional regulator
EQZ20_19210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQZ20_19215	COG0395	ABC-type sugar transport system, permease component
EQZ20_19220	COG1175	transmembrane transport
EQZ20_19225	COG1653	transport
EQZ20_19230	COG2222	sugar isomerase
EQZ20_19250	COG2068	MobA-Related Protein
EQZ20_19255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EQZ20_19260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQZ20_19305	COG5444	nuclease activity
EQZ20_19345	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_19350	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQZ20_19360	COG5280	Phage tail tape measure protein TP901
EQZ20_19360	COG3953	SLT domain
EQZ20_19420	COG4626	Terminase
EQZ20_19420	COG1802	Transcriptional regulator
EQZ20_19470	COG1598	PFAM Uncharacterised protein family UPF0150
EQZ20_19580	COG4974	Belongs to the 'phage' integrase family
EQZ20_19585	COG0719	Fe-S assembly protein
EQZ20_19590	COG0822	iron-sulfur transferase activity
EQZ20_19595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EQZ20_19600	COG0719	Fe-S assembly protein
EQZ20_19605	COG0396	ATPase activity
EQZ20_19615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQZ20_19620	COG1464	Belongs to the NlpA lipoprotein family
EQZ20_19625	COG2011	ABC-type metal ion transport system permease component
EQZ20_19630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQZ20_19640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ20_19645	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQZ20_19655	COG0509	glycine decarboxylation via glycine cleavage system
EQZ20_19660	COG1393	Belongs to the ArsC family
EQZ20_19665	COG1960	acyl-CoA dehydrogenase activity
EQZ20_19670	COG0183	Belongs to the thiolase family
EQZ20_19675	COG1250	3-hydroxyacyl-CoA dehydrogenase
EQZ20_19675	COG1024	Enoyl-CoA hydratase
EQZ20_19690	COG5577	PFAM Coat F domain
EQZ20_19705	COG1120	ATPase activity
EQZ20_19710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_19715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_19720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQZ20_19735	COG1686	Belongs to the peptidase S11 family
EQZ20_19740	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_19745	COG0783	Belongs to the Dps family
EQZ20_19755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQZ20_19760	COG0745	RESPONSE REGULATOR receiver
EQZ20_19765	COG2770	Histidine kinase
EQZ20_19765	COG2205	protein histidine kinase activity
EQZ20_19770	COG1309	transcriptional regulator
EQZ20_19775	COG0114	fumarate hydratase activity
EQZ20_19785	COG0697	spore germination
EQZ20_19790	COG0814	amino acid
EQZ20_19805	COG2197	response regulator
EQZ20_19810	COG4585	Histidine kinase
EQZ20_19815	COG4758	membrane
EQZ20_19825	COG1842	Phage shock protein A
EQZ20_19830	COG4758	membrane
EQZ20_19845	COG2096	Adenosyltransferase
EQZ20_19850	COG1120	ATPase activity
EQZ20_19855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_19860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQZ20_19865	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_19870	COG2258	MOSC domain
EQZ20_19875	COG0583	DNA-binding transcription factor activity
EQZ20_19885	COG2721	sulfolactate sulfo-lyase activity
EQZ20_19890	COG0246	Mannitol dehydrogenase
EQZ20_19895	COG1609	Transcriptional regulator
EQZ20_19900	COG2211	Major facilitator Superfamily
EQZ20_19905	COG1904	glucuronate isomerase
EQZ20_19910	COG2205	protein histidine kinase activity
EQZ20_19915	COG0745	RESPONSE REGULATOR receiver
EQZ20_19920	COG1120	ATPase activity
EQZ20_19925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_19930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_19935	COG0531	amino acid
EQZ20_19950	COG1368	sulfuric ester hydrolase activity
EQZ20_19955	COG2814	Major facilitator Superfamily
EQZ20_19960	COG0656	L-ascorbic acid biosynthetic process
EQZ20_19965	COG1940	carbohydrate kinase activity
EQZ20_19975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EQZ20_19985	COG3973	AAA domain
EQZ20_19990	COG2860	membrane
EQZ20_19995	COG0456	acetyltransferase
EQZ20_19995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EQZ20_20000	COG0456	acetyltransferase
EQZ20_20005	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EQZ20_20010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EQZ20_20015	COG2217	Heavy metal translocating P-type atpase
EQZ20_20030	COG0395	ABC-type sugar transport system, permease component
EQZ20_20035	COG1501	Belongs to the glycosyl hydrolase 31 family
EQZ20_20040	COG1472	Belongs to the glycosyl hydrolase 3 family
EQZ20_20045	COG1121	(ABC) transporter
EQZ20_20050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQZ20_20055	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQZ20_20065	COG1105	Belongs to the carbohydrate kinase PfkB family
EQZ20_20070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQZ20_20070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_20070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQZ20_20085	COG2217	Heavy metal translocating P-type atpase
EQZ20_20090	COG2608	mercury ion transmembrane transporter activity
EQZ20_20095	COG1937	Protein conserved in bacteria
EQZ20_20100	COG0693	protein deglycase activity
EQZ20_20105	COG1349	DNA-binding transcription factor activity
EQZ20_20110	COG1070	Carbohydrate kinase
EQZ20_20115	COG4952	isomerase
EQZ20_20125	COG3347	Dehydrogenase
EQZ20_20125	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_20130	COG2814	Major facilitator Superfamily
EQZ20_20140	COG2814	Major facilitator Superfamily
EQZ20_20145	COG1846	Transcriptional regulator
EQZ20_20150	COG0154	amidase activity
EQZ20_20155	COG1819	glycosyl
EQZ20_20160	COG0673	inositol 2-dehydrogenase activity
EQZ20_20165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQZ20_20180	COG1191	sigma factor activity
EQZ20_20190	COG2140	Oxalate decarboxylase
EQZ20_20210	COG3507	Belongs to the glycosyl hydrolase 43 family
EQZ20_20220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQZ20_20250	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_20265	COG3953	SLT domain
EQZ20_20265	COG5280	Phage tail tape measure protein TP901
EQZ20_20355	COG1598	PFAM Uncharacterised protein family UPF0150
EQZ20_20360	COG0582	viral genome integration into host DNA
EQZ20_20430	COG3617	BRO family, N-terminal domain
EQZ20_20445	COG1396	sequence-specific DNA binding
EQZ20_20455	COG0582	viral genome integration into host DNA
EQZ20_20465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EQZ20_20470	COG0557	exoribonuclease II activity
EQZ20_20475	COG1647	Serine aminopeptidase, S33
EQZ20_20480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQZ20_20485	COG2002	toxin-antitoxin pair type II binding
EQZ20_20490	COG1476	TRANSCRIPTIONal
EQZ20_20495	COG1396	sequence-specific DNA binding
EQZ20_20500	COG1396	sequence-specific DNA binding
EQZ20_20505	COG1174	glycine betaine transport
EQZ20_20510	COG1732	Glycine betaine
EQZ20_20515	COG1174	glycine betaine transport
EQZ20_20520	COG0517	IMP dehydrogenase activity
EQZ20_20520	COG1125	glycine betaine transport
EQZ20_20525	COG1510	regulation of RNA biosynthetic process
EQZ20_20535	COG2095	MarC family integral membrane protein
EQZ20_20540	COG3064	Membrane
EQZ20_20550	COG4640	response to antibiotic
EQZ20_20555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQZ20_20565	COG0148	phosphopyruvate hydratase activity
EQZ20_20570	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EQZ20_20575	COG0149	triose-phosphate isomerase activity
EQZ20_20580	COG0126	phosphoglycerate kinase activity
EQZ20_20585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQZ20_20590	COG2390	Transcriptional regulator
EQZ20_20595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQZ20_20600	COG1113	amino acid transport
EQZ20_20625	COG4585	Histidine kinase
EQZ20_20630	COG2197	response regulator
EQZ20_20655	COG4978	Transcriptional regulator
EQZ20_20655	COG0789	Transcriptional regulator
EQZ20_20665	COG1556	Lactate utilization protein
EQZ20_20670	COG1139	Iron-sulfur cluster binding protein
EQZ20_20675	COG0247	lactate metabolic process
EQZ20_20680	COG2186	Transcriptional regulator
EQZ20_20685	COG1620	l-lactate permease
EQZ20_20690	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EQZ20_20700	COG5039	Polysaccharide pyruvyl transferase
EQZ20_20705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQZ20_20710	COG0110	maltose O-acetyltransferase activity
EQZ20_20715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EQZ20_20720	COG2244	polysaccharide biosynthetic process
EQZ20_20725	COG1216	Glycosyl transferase, family 2
EQZ20_20730	COG5039	Polysaccharide pyruvyl transferase
EQZ20_20735	COG1216	Glycosyl transferase, family 2
EQZ20_20745	COG0438	transferase activity, transferring glycosyl groups
EQZ20_20750	COG1215	transferase activity, transferring glycosyl groups
EQZ20_20755	COG0438	transferase activity, transferring glycosyl groups
EQZ20_20760	COG1086	Polysaccharide biosynthesis protein
EQZ20_20765	COG0489	protein tyrosine kinase activity
EQZ20_20770	COG3944	biosynthesis protein
EQZ20_20775	COG1396	sequence-specific DNA binding
EQZ20_20780	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQZ20_20785	COG2271	Major facilitator Superfamily
EQZ20_20795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EQZ20_20805	COG1454	alcohol dehydrogenase
EQZ20_20810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQZ20_20835	COG1621	beta-fructofuranosidase activity
EQZ20_20840	COG1621	beta-fructofuranosidase activity
EQZ20_20875	COG1388	LysM domain
EQZ20_20875	COG3409	Peptidoglycan-binding domain 1 protein
EQZ20_20875	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQZ20_20900	COG5434	Belongs to the glycosyl hydrolase 28 family
EQZ20_20995	COG0582	viral genome integration into host DNA
EQZ20_21085	COG3584	3D domain protein
EQZ20_21090	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EQZ20_21100	COG0756	dUTP diphosphatase activity
EQZ20_21125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQZ20_21130	COG1780	Probably involved in ribonucleotide reductase function
EQZ20_21165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ20_21165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ20_21220	COG3617	BRO family, N-terminal domain
EQZ20_21285	COG4974	Belongs to the 'phage' integrase family
EQZ20_21295	COG0740	serine-type endopeptidase activity
EQZ20_21305	COG1611	Belongs to the LOG family
EQZ20_21310	COG1694	Mazg nucleotide pyrophosphohydrolase
EQZ20_21315	COG1078	dGTPase activity
EQZ20_21330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQZ20_21335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQZ20_21340	COG0640	Transcriptional regulator
EQZ20_21345	COG0577	efflux transmembrane transporter activity
EQZ20_21350	COG1136	(ABC) transporter
EQZ20_21355	COG5002	protein histidine kinase activity
EQZ20_21360	COG0745	RESPONSE REGULATOR receiver
EQZ20_21365	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EQZ20_21370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_21375	COG1481	regulation of sporulation
EQZ20_21380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EQZ20_21385	COG1660	Displays ATPase and GTPase activities
EQZ20_21390	COG1051	belongs to the nudix hydrolase family
EQZ20_21400	COG0492	ferredoxin-NADP+ reductase activity
EQZ20_21405	COG0457	Tetratricopeptide repeat
EQZ20_21415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EQZ20_21415	COG0140	phosphoribosyl-ATP diphosphatase activity
EQZ20_21420	COG0107	imidazoleglycerol-phosphate synthase activity
EQZ20_21425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EQZ20_21430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EQZ20_21435	COG0131	Imidazoleglycerol-phosphate dehydratase
EQZ20_21440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EQZ20_21445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EQZ20_21450	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EQZ20_21455	COG4990	cell redox homeostasis
EQZ20_21465	COG5297	Belongs to the glycosyl hydrolase family 6
EQZ20_21470	COG0110	maltose O-acetyltransferase activity
EQZ20_21475	COG0546	phosphoglycolate phosphatase activity
EQZ20_21480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EQZ20_21485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EQZ20_21490	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EQZ20_21495	COG1846	Transcriptional regulator
EQZ20_21500	COG2814	Major facilitator Superfamily
EQZ20_21505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EQZ20_21510	COG1950	PFAM Membrane protein of
EQZ20_21515	COG1983	PspC domain protein
EQZ20_21520	COG3595	metallopeptidase activity
EQZ20_21535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQZ20_21540	COG0556	nucleotide-excision repair
EQZ20_21545	COG4897	Protein conserved in bacteria
EQZ20_21555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQZ20_21565	COG0793	Belongs to the peptidase S41A family
EQZ20_21565	COG3409	Peptidoglycan-binding domain 1 protein
EQZ20_21570	COG0473	3-isopropylmalate dehydrogenase activity
EQZ20_21575	COG3883	PFAM NLP P60 protein
EQZ20_21575	COG0791	NLP P60 protein
EQZ20_21580	COG2177	Part of the ABC transporter FtsEX involved in
EQZ20_21585	COG2884	Cell division ATP-binding protein ftsE
EQZ20_21590	COG2010	Cytochrome c
EQZ20_21595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ20_21605	COG0653	protein targeting
EQZ20_21610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EQZ20_21625	COG1516	flagellar protein fliS
EQZ20_21630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EQZ20_21635	COG1334	flagellar protein FlaG
EQZ20_21640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQZ20_21645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQZ20_21650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQZ20_21655	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EQZ20_21660	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EQZ20_21670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQZ20_21675	COG1256	bacterial-type flagellum assembly
EQZ20_21675	COG4786	Flagellar basal body rod
EQZ20_21680	COG3418	PFAM FlgN family protein
EQZ20_21685	COG2747	anti-sigma28 factor FlgM
EQZ20_21705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EQZ20_21710	COG1307	EDD domain protein, DegV family
EQZ20_21715	COG2197	response regulator
EQZ20_21720	COG4585	Histidine kinase
EQZ20_21725	COG1739	Uncharacterized protein family UPF0029
EQZ20_21730	COG1316	TRANSCRIPTIONal
EQZ20_21735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQZ20_21740	COG0438	transferase activity, transferring glycosyl groups
EQZ20_21745	COG1215	transferase activity, transferring glycosyl groups
EQZ20_21750	COG3206	protein involved in exopolysaccharide biosynthesis
EQZ20_21755	COG3307	-O-antigen
EQZ20_21760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQZ20_21765	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EQZ20_21770	COG0297	glycogen (starch) synthase activity
EQZ20_21770	COG0438	transferase activity, transferring glycosyl groups
EQZ20_21775	COG2244	polysaccharide biosynthetic process
EQZ20_21785	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQZ20_21785	COG2247	cell wall binding repeat
EQZ20_21790	COG2247	cell wall binding repeat
EQZ20_21790	COG2385	sporulation resulting in formation of a cellular spore
EQZ20_21800	COG1316	TRANSCRIPTIONal
EQZ20_21805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EQZ20_21810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQZ20_21815	COG1134	teichoic acid transport
EQZ20_21820	COG1682	transport, permease protein
EQZ20_21840	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQZ20_21850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EQZ20_21855	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EQZ20_21860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQZ20_21865	COG4193	domain, Protein
EQZ20_21870	COG1482	cell wall glycoprotein biosynthetic process
EQZ20_21880	COG1328	CTP reductase activity
EQZ20_21890	COG0800	Aldolase
EQZ20_21895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQZ20_21900	COG1609	Transcriptional regulator
EQZ20_21905	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EQZ20_21910	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_21920	COG2814	Major facilitator Superfamily
EQZ20_21925	COG1316	TRANSCRIPTIONal
EQZ20_21930	COG0561	phosphatase activity
EQZ20_21935	COG0791	NLP P60 protein
EQZ20_21940	COG2843	Capsule synthesis protein
EQZ20_21950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQZ20_21955	COG1609	Transcriptional regulator
EQZ20_21960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQZ20_21965	COG1869	D-ribose catabolic process
EQZ20_21970	COG1129	ABC transporter
EQZ20_21975	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQZ20_21980	COG1879	ABC-type sugar transport system periplasmic component
EQZ20_21985	COG0583	DNA-binding transcription factor activity
EQZ20_21990	COG2226	methyltransferase
EQZ20_21995	COG3527	Alpha-acetolactate decarboxylase
EQZ20_22000	COG0028	Belongs to the TPP enzyme family
EQZ20_22005	COG0583	DNA-binding transcription factor activity
EQZ20_22020	COG1522	sequence-specific DNA binding
EQZ20_22025	COG2059	Chromate
EQZ20_22030	COG2059	Chromate
EQZ20_22035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EQZ20_22040	COG4464	protein tyrosine phosphatase activity
EQZ20_22045	COG3944	biosynthesis protein
EQZ20_22055	COG4715	Zinc finger, swim domain protein
EQZ20_22060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EQZ20_22065	COG0831	urea catabolic process
EQZ20_22070	COG0832	Belongs to the urease beta subunit family
EQZ20_22080	COG0561	phosphatase activity
EQZ20_22085	COG1349	DNA-binding transcription factor activity
EQZ20_22095	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_22105	COG3732	PTS system glucitol sorbitol-specific
EQZ20_22125	COG0629	single-stranded DNA binding
EQZ20_22140	COG1970	mechanosensitive ion channel activity
EQZ20_22145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQZ20_22150	COG4786	Flagellar basal body rod
EQZ20_22155	COG4786	Flagellar basal body rod
EQZ20_22160	COG1077	Cell shape determining protein MreB Mrl
EQZ20_22165	COG1609	Transcriptional regulator
EQZ20_22175	COG1846	Transcriptional regulator
EQZ20_22180	COG2814	Major facilitator Superfamily
EQZ20_22185	COG0671	phosphoesterase, PA-phosphatase related
EQZ20_22195	COG1227	inorganic diphosphatase activity
EQZ20_22200	COG3546	catalase activity
EQZ20_22205	COG3361	conserved protein (COG2071)
EQZ20_22210	COG0517	IMP dehydrogenase activity
EQZ20_22215	COG0598	Magnesium transport protein CorA
EQZ20_22220	COG1253	flavin adenine dinucleotide binding
EQZ20_22225	COG0004	ammonium transporteR
EQZ20_22230	COG0347	Belongs to the P(II) protein family
EQZ20_22235	COG0740	serine-type endopeptidase activity
EQZ20_22245	COG0739	heme binding
EQZ20_22250	COG1247	-acetyltransferase
EQZ20_22260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQZ20_22265	COG0477	Major facilitator Superfamily
EQZ20_22270	COG3251	PFAM MbtH domain protein
EQZ20_22275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQZ20_22280	COG3433	isochorismatase activity
EQZ20_22280	COG1535	isochorismatase
EQZ20_22285	COG1021	2,3-dihydroxybenzoate-AMP ligase
EQZ20_22290	COG1169	isochorismate synthase
EQZ20_22295	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ20_22300	COG2819	hydrolase of the alpha beta superfamily
EQZ20_22305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_22310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQZ20_22315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQZ20_22320	COG2207	Transcriptional regulator
EQZ20_22320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQZ20_22330	COG2910	NAD(P)H-binding
EQZ20_22335	COG1959	2 iron, 2 sulfur cluster binding
EQZ20_22345	COG1994	Peptidase M50
EQZ20_22350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EQZ20_22355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EQZ20_22370	COG2304	oxidoreductase activity
EQZ20_22375	COG2304	oxidoreductase activity
EQZ20_22380	COG2385	sporulation resulting in formation of a cellular spore
EQZ20_22385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQZ20_22395	COG4836	Membrane
EQZ20_22400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EQZ20_22405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EQZ20_22410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EQZ20_22415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EQZ20_22420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQZ20_22425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EQZ20_22430	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQZ20_22450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EQZ20_22455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EQZ20_22460	COG4475	Protein of unknown function (DUF436)
EQZ20_22465	COG0698	ribose 5-phosphate isomerase
EQZ20_22470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQZ20_22475	COG1971	Probably functions as a manganese efflux pump
EQZ20_22480	COG0009	L-threonylcarbamoyladenylate synthase
EQZ20_22485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EQZ20_22495	COG0738	Major facilitator superfamily
EQZ20_22505	COG0561	phosphatase activity
EQZ20_22515	COG1609	Transcriptional regulator
EQZ20_22520	COG2890	protein-(glutamine-N5) methyltransferase activity
EQZ20_22525	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EQZ20_22530	COG0346	lactoylglutathione lyase activity
EQZ20_22535	COG0789	Transcriptional regulator
EQZ20_22540	COG0679	Auxin Efflux Carrier
EQZ20_22545	COG0281	malic enzyme
EQZ20_22550	COG1435	thymidine kinase activity
EQZ20_22555	COG0254	rRNA binding
EQZ20_22560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EQZ20_22565	COG1494	fructose-1,6-bisphosphatase
EQZ20_22570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQZ20_22575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EQZ20_22580	COG0191	fructose-bisphosphate aldolase activity
EQZ20_22585	COG2204	response regulator
EQZ20_22590	COG4821	SIS domain
EQZ20_22595	COG0504	CTP synthase activity
EQZ20_22600	COG3343	RNA polymerase activity
EQZ20_22610	COG1960	acyl-CoA dehydrogenase activity
EQZ20_22615	COG1960	acyl-CoA dehydrogenase activity
EQZ20_22620	COG1250	3-hydroxyacyl-CoA dehydrogenase
EQZ20_22625	COG0183	Belongs to the thiolase family
EQZ20_22630	COG2181	nitrate reductase activity
EQZ20_22630	COG0247	lactate metabolic process
EQZ20_22640	COG0018	arginyl-trna synthetase
EQZ20_22645	COG4506	Protein conserved in bacteria
EQZ20_22650	COG0010	Belongs to the arginase family
EQZ20_22655	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EQZ20_22660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQZ20_22670	COG1994	Peptidase M50
EQZ20_22675	COG1942	4-Oxalocrotonate Tautomerase
EQZ20_22685	COG3465	dGTPase activity
EQZ20_22690	COG1078	dGTPase activity
EQZ20_22695	COG4844	belongs to the
EQZ20_22725	COG2814	Major facilitator Superfamily
EQZ20_22750	COG1414	Transcriptional regulator
EQZ20_22760	COG0280	phosphate acetyltransferase
EQZ20_22775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQZ20_22800	COG1131	(ABC) transporter
EQZ20_22810	COG2197	response regulator
EQZ20_22815	COG2363	Small membrane protein
EQZ20_22820	COG2233	PERMEase
EQZ20_22830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EQZ20_22835	COG1216	Glycosyl transferase, family 2
EQZ20_22840	COG0351	phosphomethylpyrimidine kinase
EQZ20_22850	COG1621	beta-fructofuranosidase activity
EQZ20_22855	COG1263	PTS System
EQZ20_22855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_22860	COG3711	transcriptional antiterminator
EQZ20_22870	COG1404	Belongs to the peptidase S8 family
EQZ20_22880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQZ20_22885	COG0778	Nitroreductase
EQZ20_22890	COG1473	amidohydrolase
EQZ20_22895	COG0772	Belongs to the SEDS family
EQZ20_22900	COG0772	Belongs to the SEDS family
EQZ20_22920	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQZ20_22930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQZ20_22935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQZ20_22940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQZ20_22950	COG0655	NAD(P)H dehydrogenase (quinone) activity
EQZ20_22955	COG3162	membrane
EQZ20_22960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQZ20_22965	COG1070	Carbohydrate kinase
EQZ20_22970	COG2115	Belongs to the xylose isomerase family
EQZ20_22980	COG0352	thiamine-phosphate diphosphorylase activity
EQZ20_22985	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EQZ20_22990	COG0583	DNA-binding transcription factor activity
EQZ20_23005	COG1380	Effector of murein hydrolase LrgA
EQZ20_23010	COG1346	cytolysis
EQZ20_23015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQZ20_23020	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EQZ20_23030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQZ20_23035	COG1442	glycosyl transferase family 8
EQZ20_23040	COG5522	Integral membrane protein (intg_mem_TP0381)
EQZ20_23045	COG2271	Major facilitator Superfamily
EQZ20_23050	COG4948	Mandelate Racemase Muconate Lactonizing
EQZ20_23055	COG0800	Aldolase
EQZ20_23060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQZ20_23065	COG1414	Transcriptional regulator
EQZ20_23070	COG2234	aminopeptidase activity
EQZ20_23100	COG0477	Major facilitator Superfamily
EQZ20_23105	COG1335	isochorismatase
EQZ20_23115	COG2357	RelA SpoT domain protein
EQZ20_23130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQZ20_23135	COG1696	Membrane protein involved in D-alanine export
EQZ20_23140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQZ20_23145	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EQZ20_23150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQZ20_23155	COG2814	Major facilitator Superfamily
EQZ20_23160	COG1486	melibiose metabolic process
EQZ20_23165	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQZ20_23170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ20_23175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ20_23180	COG3711	transcriptional antiterminator
EQZ20_23180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ20_23185	COG2094	Belongs to the DNA glycosylase MPG family
EQZ20_23195	COG1086	Polysaccharide biosynthesis protein
EQZ20_23210	COG0372	Belongs to the citrate synthase family
EQZ20_23215	COG2079	MmgE PrpD family protein
EQZ20_23220	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EQZ20_23225	COG1132	(ABC) transporter
EQZ20_23230	COG2755	lipolytic protein G-D-S-L family
EQZ20_23250	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQZ20_23255	COG1131	(ABC) transporter
EQZ20_23275	COG1595	DNA-templated transcription, initiation
EQZ20_23280	COG2814	Major facilitator Superfamily
EQZ20_23295	COG0753	catalase activity
EQZ20_23310	COG3866	Pectate lyase
EQZ20_23315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EQZ20_23320	COG2311	Membrane
EQZ20_23325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EQZ20_23330	COG4988	ABC transporter
EQZ20_23335	COG1294	oxidase, subunit
EQZ20_23340	COG1271	oxidase subunit
EQZ20_23350	COG2116	formate transmembrane transporter activity
EQZ20_23360	COG0281	malic enzyme
EQZ20_23365	COG1757	Na H antiporter
EQZ20_23370	COG1027	Aspartate ammonia-lyase
EQZ20_23375	COG0252	asparaginase activity
EQZ20_23380	COG1396	sequence-specific DNA binding
EQZ20_23385	COG2706	6-phosphogluconolactonase activity
EQZ20_23390	COG0745	RESPONSE REGULATOR receiver
EQZ20_23395	COG2205	protein histidine kinase activity
EQZ20_23400	COG1136	(ABC) transporter
EQZ20_23405	COG0577	efflux transmembrane transporter activity
EQZ20_23410	COG5294	Protein conserved in bacteria
EQZ20_23425	COG0726	polysaccharide deacetylase
EQZ20_23435	COG3493	citrate carrier protein
EQZ20_23440	COG0584	glycerophosphoryl diester phosphodiesterase
EQZ20_23460	COG5444	nuclease activity
EQZ20_23470	COG1368	sulfuric ester hydrolase activity
EQZ20_23490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ20_23495	COG1438	arginine binding
EQZ20_23505	COG2235	arginine
EQZ20_23510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EQZ20_23520	COG0549	Belongs to the carbamate kinase family
EQZ20_23545	COG0745	RESPONSE REGULATOR receiver
EQZ20_23550	COG2205	protein histidine kinase activity
EQZ20_23555	COG2723	6-phospho-beta-galactosidase activity
EQZ20_23560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ20_23570	COG1595	DNA-templated transcription, initiation
EQZ20_23580	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQZ20_23590	COG1621	beta-fructofuranosidase activity
EQZ20_23595	COG2223	nitrite transmembrane transporter activity
EQZ20_23600	COG1609	Transcriptional regulator
EQZ20_23615	COG0235	Class ii aldolase
EQZ20_23625	COG3775	system Galactitol-specific IIC component
EQZ20_23630	COG3414	Phosphotransferase system galactitol-specific IIB component
EQZ20_23645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQZ20_23655	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EQZ20_23660	COG0463	Glycosyl transferase, family 2
EQZ20_23665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQZ20_23670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQZ20_23675	COG0753	catalase activity
EQZ20_23675	COG0693	protein deglycase activity
EQZ20_23680	COG2851	Citrate transporter
EQZ20_23685	COG2723	6-phospho-beta-galactosidase activity
EQZ20_23690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_23690	COG2190	(PTS) system
EQZ20_23690	COG1263	PTS System
EQZ20_23695	COG3711	transcriptional antiterminator
EQZ20_23700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQZ20_23705	COG1122	ATPase activity
EQZ20_23710	COG4721	ABC-type cobalt transport system, permease component
EQZ20_23715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQZ20_23725	COG2224	Isocitrate lyase
EQZ20_23730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EQZ20_23740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EQZ20_23745	COG2723	6-phospho-beta-galactosidase activity
EQZ20_23750	COG1263	PTS System
EQZ20_23750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_23750	COG2190	(PTS) system
EQZ20_23760	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EQZ20_23765	COG3507	Belongs to the glycosyl hydrolase 43 family
EQZ20_23770	COG0513	Belongs to the DEAD box helicase family
EQZ20_23780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EQZ20_23785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQZ20_23790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EQZ20_23795	COG2390	Transcriptional regulator
EQZ20_23800	COG0457	Tetratricopeptide repeat
EQZ20_23805	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EQZ20_23810	COG3706	GGDEF domain
EQZ20_23815	COG5298	Protein conserved in bacteria
EQZ20_23820	COG1215	transferase activity, transferring glycosyl groups
EQZ20_23830	COG3977	Valine--pyruvate aminotransferase
EQZ20_23845	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQZ20_23855	COG0191	fructose-bisphosphate aldolase activity
EQZ20_23860	COG1082	Xylose isomerase domain protein TIM barrel
EQZ20_23865	COG1082	Xylose isomerase domain protein TIM barrel
EQZ20_23870	COG0673	inositol 2-dehydrogenase activity
EQZ20_23880	COG1082	Xylose isomerase domain protein TIM barrel
EQZ20_23885	COG3962	Belongs to the TPP enzyme family
EQZ20_23890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQZ20_23895	COG3718	enzyme involved in inositol metabolism
EQZ20_23900	COG1012	belongs to the aldehyde dehydrogenase family
EQZ20_23905	COG1349	DNA-binding transcription factor activity
EQZ20_23910	COG0667	Aldo Keto reductase
EQZ20_23920	COG2271	Major facilitator Superfamily
EQZ20_23925	COG0326	Molecular chaperone. Has ATPase activity
EQZ20_23930	COG0488	(ABC) transporter
EQZ20_23935	COG0561	phosphatase activity
EQZ20_23955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQZ20_23975	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EQZ20_23980	COG0577	efflux transmembrane transporter activity
EQZ20_23985	COG1136	(ABC) transporter
EQZ20_23990	COG2205	protein histidine kinase activity
EQZ20_23995	COG0745	RESPONSE REGULATOR receiver
EQZ20_24005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQZ20_24010	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EQZ20_24015	COG1874	Beta-galactosidase
EQZ20_24020	COG3833	ABC-type maltose transport systems, permease component
EQZ20_24025	COG1175	transmembrane transport
EQZ20_24030	COG2182	Extracellular solute-binding protein
EQZ20_24035	COG1609	Transcriptional regulator
EQZ20_24045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQZ20_24050	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EQZ20_24055	COG1940	carbohydrate kinase activity
EQZ20_24060	COG1802	Transcriptional regulator
EQZ20_24065	COG1070	Carbohydrate kinase
EQZ20_24070	COG2610	gluconate transmembrane transporter activity
EQZ20_24075	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EQZ20_24080	COG1012	belongs to the aldehyde dehydrogenase family
EQZ20_24080	COG1454	alcohol dehydrogenase
EQZ20_24090	COG0450	alkyl hydroperoxide reductase
EQZ20_24095	COG3634	alkyl hydroperoxide reductase activity
EQZ20_24100	COG2723	6-phospho-beta-galactosidase activity
EQZ20_24110	COG2188	Transcriptional regulator
EQZ20_24125	COG1131	(ABC) transporter
EQZ20_24130	COG0842	Transport permease protein
EQZ20_24135	COG4585	Histidine kinase
EQZ20_24140	COG2197	response regulator
EQZ20_24155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EQZ20_24170	COG0456	acetyltransferase
EQZ20_24185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQZ20_24190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EQZ20_24195	COG4853	Protein conserved in bacteria
EQZ20_24200	COG4863	YycH protein
EQZ20_24205	COG5002	protein histidine kinase activity
EQZ20_24210	COG0745	RESPONSE REGULATOR receiver
EQZ20_24235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EQZ20_24245	COG0305	Participates in initiation and elongation during chromosome replication
EQZ20_24255	COG3093	addiction module antidote protein HigA
EQZ20_24260	COG2807	transmembrane transport
EQZ20_24265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EQZ20_24270	COG0363	glucosamine-6-phosphate deaminase activity
EQZ20_24280	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EQZ20_24285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ20_24285	COG1263	PTS System
EQZ20_24290	COG0359	binds to the 23S rRNA
EQZ20_24295	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EQZ20_24300	COG4241	membrane
EQZ20_24310	COG0659	secondary active sulfate transmembrane transporter activity
EQZ20_24315	COG2271	Major facilitator Superfamily
EQZ20_24320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EQZ20_24325	COG0629	single-stranded DNA binding
EQZ20_24330	COG0360	Binds together with S18 to 16S ribosomal RNA
EQZ20_24335	COG0012	GTP binding
EQZ20_24340	COG4481	Protein conserved in bacteria
EQZ20_24345	COG3949	Membrane
EQZ20_24355	COG1475	DNA binding
EQZ20_24360	COG1192	Involved in chromosome partitioning
EQZ20_24365	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQZ20_24370	COG1595	DNA-templated transcription, initiation
EQZ20_24375	COG1475	DNA binding
EQZ20_24380	COG0357	Ribosomal RNA small subunit methyltransferase G
EQZ20_24385	COG0445	tRNA wobble uridine modification
EQZ20_24390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EQZ20_24395	COG1847	R3H domain protein
EQZ20_24400	COG0706	membrane insertase activity
EQZ20_24405	COG0594	ribonuclease P activity
EQZ20_24410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EQZ20_24510	COG0582	viral genome integration into host DNA
EQZ20_24560	COG3883	PFAM NLP P60 protein
EQZ20_24560	COG0791	NLP P60 protein
EQZ20_24690	COG0457	Tetratricopeptide repeat
