locus-tag	class	description
FLQ13_00030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_00035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLQ13_00055	COG0492	ferredoxin-NADP+ reductase activity
FLQ13_00060	COG3118	belongs to the thioredoxin family
FLQ13_00070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_00080	COG0509	glycine decarboxylation via glycine cleavage system
FLQ13_00090	COG1309	transcriptional regulator
FLQ13_00110	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FLQ13_00130	COG0583	DNA-binding transcription factor activity
FLQ13_00140	COG2085	NADP oxidoreductase coenzyme F420-dependent
FLQ13_00145	COG1733	regulation of RNA biosynthetic process
FLQ13_00180	COG2732	(Barnase) inhibitor
FLQ13_00210	COG1725	Transcriptional regulator
FLQ13_00230	COG0747	negative chemotaxis
FLQ13_00235	COG0601	transmembrane transport
FLQ13_00240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLQ13_00245	COG0444	Belongs to the ABC transporter superfamily
FLQ13_00250	COG4608	Belongs to the ABC transporter superfamily
FLQ13_00255	COG3443	Belongs to the bacterial solute-binding protein 9 family
FLQ13_00265	COG4991	sh3 domain protein
FLQ13_00270	COG4991	sh3 domain protein
FLQ13_00295	COG0789	Transcriptional regulator
FLQ13_00305	COG1064	alcohol dehydrogenase
FLQ13_00310	COG0693	protein deglycase activity
FLQ13_00315	COG1621	beta-fructofuranosidase activity
FLQ13_00320	COG3716	PTS system mannose fructose sorbose family IID component
FLQ13_00330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_00335	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLQ13_00350	COG1280	lysine exporter protein (LysE YggA)
FLQ13_00355	COG1378	Sugar-specific transcriptional regulator TrmB
FLQ13_00360	COG1595	DNA-templated transcription, initiation
FLQ13_00370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FLQ13_00370	COG2755	lipolytic protein G-D-S-L family
FLQ13_00380	COG2124	cytochrome p450
FLQ13_00380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FLQ13_00385	COG1309	transcriptional regulator
FLQ13_00390	COG2226	methyltransferase
FLQ13_00405	COG2116	formate transmembrane transporter activity
FLQ13_00410	COG5609	conserved protein (DUF2294)
FLQ13_00415	COG3383	formate dehydrogenase (NAD+) activity
FLQ13_00420	COG2427	Protein of unknown function (DUF1641)
FLQ13_00435	COG0626	cystathionine gamma-synthase activity
FLQ13_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLQ13_00445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FLQ13_00450	COG2226	methyltransferase
FLQ13_00465	COG0768	penicillin binding
FLQ13_00470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLQ13_00475	COG0572	uridine kinase
FLQ13_00495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLQ13_00500	COG3906	Belongs to the UPF0473 family
FLQ13_00505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FLQ13_00510	COG4472	Bacterial protein of unknown function (DUF965)
FLQ13_00515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FLQ13_00520	COG0628	permease
FLQ13_00525	COG1126	abc transporter atp-binding protein
FLQ13_00530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLQ13_00535	COG0765	amino acid transport
FLQ13_00540	COG0765	amino acid transport
FLQ13_00555	COG3881	PFAM PRC-barrel domain
FLQ13_00560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FLQ13_00565	COG0457	Tetratricopeptide repeat
FLQ13_00570	COG0482	sulfurtransferase activity
FLQ13_00575	COG1104	cysteine desulfurase activity
FLQ13_00580	COG1959	2 iron, 2 sulfur cluster binding
FLQ13_00585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FLQ13_00590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FLQ13_00600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FLQ13_00605	COG0124	histidyl-tRNA synthetase
FLQ13_00615	COG4991	sh3 domain protein
FLQ13_00615	COG3103	Sh3 type 3 domain protein
FLQ13_00615	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLQ13_00620	COG1490	D-aminoacyl-tRNA deacylase activity
FLQ13_00625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLQ13_00630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLQ13_00640	COG5416	Lipopolysaccharide assembly protein A domain
FLQ13_00645	COG0490	domain, Protein
FLQ13_00650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLQ13_00650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLQ13_00665	COG2323	membrane
FLQ13_00675	COG1862	Preprotein translocase
FLQ13_00685	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FLQ13_00695	COG2255	four-way junction helicase activity
FLQ13_00700	COG0632	four-way junction helicase activity
FLQ13_00710	COG2814	Major facilitator Superfamily
FLQ13_00720	COG2112	serine threonine protein kinase
FLQ13_00735	COG1115	amino acid carrier protein
FLQ13_00740	COG0217	transcriptional regulatory protein
FLQ13_00755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FLQ13_00760	COG0157	Belongs to the NadC ModD family
FLQ13_00765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FLQ13_00770	COG1104	cysteine desulfurase activity
FLQ13_00775	COG1827	regulation of RNA biosynthetic process
FLQ13_00780	COG0077	Prephenate dehydratase
FLQ13_00785	COG4492	Belongs to the UPF0735 family
FLQ13_00790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FLQ13_00795	COG3290	protein histidine kinase activity
FLQ13_00805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FLQ13_00810	COG2868	ribosomal protein
FLQ13_00815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FLQ13_00820	COG1994	Peptidase M50
FLQ13_00825	COG0739	heme binding
FLQ13_00830	COG2894	cell division
FLQ13_00835	COG0850	regulation of cytokinetic process
FLQ13_00840	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FLQ13_00845	COG1792	Involved in formation and maintenance of cell shape
FLQ13_00850	COG1077	Cell shape determining protein MreB Mrl
FLQ13_00860	COG0424	maF-like protein
FLQ13_00870	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FLQ13_00875	COG0285	dihydrofolate synthase activity
FLQ13_00880	COG0525	valine-tRNA ligase activity
FLQ13_00890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLQ13_00895	COG1388	LysM domain
FLQ13_00900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLQ13_00905	COG0113	porphobilinogen synthase activity
FLQ13_00910	COG1587	Uroporphyrinogen-III synthase
FLQ13_00915	COG0181	hydroxymethylbilane synthase activity
FLQ13_00920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLQ13_00925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FLQ13_00935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FLQ13_00945	COG0470	DNA polymerase III
FLQ13_00945	COG1067	ATP-dependent peptidase activity
FLQ13_00950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLQ13_00955	COG0544	peptidyl-prolyl cis-trans isomerase activity
FLQ13_00960	COG1477	protein flavinylation
FLQ13_00960	COG0457	Tetratricopeptide repeat
FLQ13_00965	COG0066	3-isopropylmalate dehydratase activity
FLQ13_00970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FLQ13_00975	COG0473	3-isopropylmalate dehydrogenase activity
FLQ13_00980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLQ13_00985	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FLQ13_00990	COG0440	acetolactate synthase activity
FLQ13_00995	COG0028	Belongs to the TPP enzyme family
FLQ13_01005	COG0454	-acetyltransferase
FLQ13_01010	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FLQ13_01020	COG0622	Phosphoesterase
FLQ13_01025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLQ13_01035	COG5401	PFAM Sporulation and spore germination
FLQ13_01040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FLQ13_01045	COG1846	Transcriptional regulator
FLQ13_01050	COG2197	response regulator
FLQ13_01055	COG0824	Thioesterase
FLQ13_01060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FLQ13_01070	COG2009	succinate dehydrogenase
FLQ13_01075	COG1719	4-vinyl reductase, 4VR
FLQ13_01080	COG0527	aspartate kinase activity
FLQ13_01090	COG0322	excinuclease ABC activity
FLQ13_01095	COG3118	belongs to the thioredoxin family
FLQ13_01100	COG3534	alpha-L-arabinofuranosidase
FLQ13_01105	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FLQ13_01110	COG2086	electron transfer activity
FLQ13_01115	COG1024	Enoyl-CoA hydratase
FLQ13_01120	COG1309	transcriptional regulator
FLQ13_01125	COG0318	PFAM AMP-dependent synthetase and ligase
FLQ13_01130	COG3766	membrane
FLQ13_01135	COG1193	negative regulation of DNA recombination
FLQ13_01140	COG1796	DNA polymerase
FLQ13_01140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FLQ13_01145	COG1286	toxin biosynthetic process
FLQ13_01150	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FLQ13_01155	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLQ13_01160	COG0072	phenylalanine-tRNA ligase activity
FLQ13_01160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLQ13_01175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLQ13_01185	COG3835	regulator
FLQ13_01190	COG0277	FAD linked oxidase domain protein
FLQ13_01195	COG0247	lactate metabolic process
FLQ13_01200	COG0346	lactoylglutathione lyase activity
FLQ13_01205	COG1966	Carbon starvation protein
FLQ13_01220	COG1695	Transcriptional regulator
FLQ13_01225	COG3534	alpha-L-arabinofuranosidase
FLQ13_01230	COG0395	ABC-type sugar transport system, permease component
FLQ13_01240	COG1653	transport
FLQ13_01245	COG0371	Dehydrogenase
FLQ13_01250	COG0647	UMP catabolic process
FLQ13_01255	COG0235	Class ii aldolase
FLQ13_01260	COG1069	ribulokinase activity
FLQ13_01265	COG2160	L-arabinose isomerase activity
FLQ13_01270	COG3507	Belongs to the glycosyl hydrolase 43 family
FLQ13_01275	COG1363	Peptidase, m42
FLQ13_01285	COG3326	Membrane
FLQ13_01290	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FLQ13_01295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FLQ13_01300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FLQ13_01310	COG1346	cytolysis
FLQ13_01315	COG1380	Effector of murein hydrolase LrgA
FLQ13_01325	COG3275	phosphorelay sensor kinase activity
FLQ13_01335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLQ13_01345	COG0398	Pfam SNARE associated Golgi protein
FLQ13_01350	COG1484	DNA-dependent DNA replication
FLQ13_01355	COG3611	Membrane attachment protein
FLQ13_01360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FLQ13_01365	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FLQ13_01370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLQ13_01375	COG1733	regulation of RNA biosynthetic process
FLQ13_01380	COG2814	Major facilitator Superfamily
FLQ13_01385	COG0656	L-ascorbic acid biosynthetic process
FLQ13_01390	COG0237	dephospho-CoA kinase activity
FLQ13_01395	COG1971	Probably functions as a manganese efflux pump
FLQ13_01400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FLQ13_01405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLQ13_01405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLQ13_01410	COG5002	protein histidine kinase activity
FLQ13_01415	COG0745	RESPONSE REGULATOR receiver
FLQ13_01420	COG0039	L-malate dehydrogenase activity
FLQ13_01425	COG0538	isocitrate dehydrogenase activity
FLQ13_01430	COG0372	Belongs to the citrate synthase family
FLQ13_01440	COG0628	permease
FLQ13_01445	COG3030	protein affecting phage T7 exclusion by the F plasmid
FLQ13_01450	COG0469	pyruvate kinase activity
FLQ13_01455	COG0205	6-phosphofructokinase activity
FLQ13_01460	COG0825	malonyl-CoA metabolic process
FLQ13_01465	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FLQ13_01470	COG0281	malic enzyme
FLQ13_01475	COG0587	DNA-directed DNA polymerase activity
FLQ13_01495	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FLQ13_01505	COG4109	DRTGG domain
FLQ13_01510	COG0730	response to heat
FLQ13_01515	COG1473	amidohydrolase
FLQ13_01520	COG0196	riboflavin kinase activity
FLQ13_01530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FLQ13_01540	COG1126	abc transporter atp-binding protein
FLQ13_01545	COG0765	amino acid transport
FLQ13_01550	COG0765	amino acid transport
FLQ13_01555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLQ13_01560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLQ13_01565	COG0454	-acetyltransferase
FLQ13_01570	COG0583	DNA-binding transcription factor activity
FLQ13_01575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FLQ13_01580	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_01590	COG0165	Argininosuccinate lyase
FLQ13_01595	COG0137	argininosuccinate synthase activity
FLQ13_01600	COG0521	Mo-molybdopterin cofactor biosynthetic process
FLQ13_01605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FLQ13_01610	COG0827	DNA restriction-modification system
FLQ13_01615	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FLQ13_01620	COG3874	Sporulation protein YtfJ
FLQ13_01630	COG1714	RDD family
FLQ13_01635	COG0616	signal peptide processing
FLQ13_01640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLQ13_01645	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FLQ13_01650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLQ13_01660	COG0301	tRNA thio-modification
FLQ13_01665	COG1104	cysteine desulfurase activity
FLQ13_01670	COG1114	Component of the transport system for branched-chain amino acids
FLQ13_01675	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FLQ13_01680	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FLQ13_01685	COG1309	transcriptional regulator
FLQ13_01690	COG1956	GAF domain-containing protein
FLQ13_01710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLQ13_01715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLQ13_01720	COG0454	-acetyltransferase
FLQ13_01725	COG0517	IMP dehydrogenase activity
FLQ13_01735	COG1360	Flagellar Motor Protein
FLQ13_01740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FLQ13_01745	COG1609	Transcriptional regulator
FLQ13_01750	COG1605	Chorismate mutase
FLQ13_01750	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FLQ13_01760	COG4980	gas vesicle protein
FLQ13_01765	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FLQ13_01770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FLQ13_01775	COG1674	ftsk spoiiie
FLQ13_01780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLQ13_01785	COG4848	Belongs to the UPF0354 family
FLQ13_01790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_01805	COG1363	Peptidase, m42
FLQ13_01810	COG5584	Small secreted protein
FLQ13_01815	COG0281	malic enzyme
FLQ13_01825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FLQ13_01835	COG0510	thiamine kinase activity
FLQ13_01840	COG1523	belongs to the glycosyl hydrolase 13 family
FLQ13_01845	COG1597	lipid kinase activity
FLQ13_01855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FLQ13_01860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLQ13_01865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLQ13_01870	COG2252	PERMEase
FLQ13_01875	COG4473	ABC transporter
FLQ13_01880	COG1131	(ABC) transporter
FLQ13_01885	COG1349	DNA-binding transcription factor activity
FLQ13_01890	COG1187	pseudouridine synthase activity
FLQ13_01895	COG2244	polysaccharide biosynthetic process
FLQ13_01915	COG5578	integral membrane protein
FLQ13_01925	COG1653	transport
FLQ13_01940	COG2207	Transcriptional regulator
FLQ13_01945	COG1653	transport
FLQ13_01950	COG0395	ABC-type sugar transport system, permease component
FLQ13_01955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLQ13_01960	COG2124	cytochrome p450
FLQ13_01965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FLQ13_01975	COG0156	8-amino-7-oxononanoate synthase activity
FLQ13_01980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLQ13_02015	COG1486	melibiose metabolic process
FLQ13_02025	COG0495	leucyl-tRNA aminoacylation
FLQ13_02035	COG2202	Pas domain
FLQ13_02035	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_02040	COG2814	Major facilitator Superfamily
FLQ13_02045	COG2433	Pfam Transposase IS66
FLQ13_02055	COG1136	(ABC) transporter
FLQ13_02060	COG2205	protein histidine kinase activity
FLQ13_02065	COG0745	RESPONSE REGULATOR receiver
FLQ13_02070	COG0577	efflux transmembrane transporter activity
FLQ13_02075	COG1136	(ABC) transporter
FLQ13_02090	COG1131	(ABC) transporter
FLQ13_02105	COG1242	4 iron, 4 sulfur cluster binding
FLQ13_02110	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FLQ13_02120	COG2267	carboxylic ester hydrolase activity
FLQ13_02125	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FLQ13_02130	COG1113	amino acid transport
FLQ13_02135	COG0367	asparagine synthase
FLQ13_02140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FLQ13_02145	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FLQ13_02155	COG1506	peptidase
FLQ13_02160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLQ13_02165	COG1116	anion transmembrane transporter activity
FLQ13_02170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLQ13_02175	COG0494	nUDIX hydrolase
FLQ13_02180	COG4824	toxin secretion phage lysis holin
FLQ13_02185	COG0783	Belongs to the Dps family
FLQ13_02200	COG1854	S-ribosylhomocysteine lyase activity
FLQ13_02205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FLQ13_02210	COG0288	reversible hydration of carbon dioxide
FLQ13_02215	COG0254	rRNA binding
FLQ13_02220	COG1271	oxidase subunit
FLQ13_02225	COG1294	oxidase, subunit
FLQ13_02235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLQ13_02240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLQ13_02240	COG1321	iron dependent repressor
FLQ13_02245	COG1121	(ABC) transporter
FLQ13_02250	COG0803	Belongs to the bacterial solute-binding protein 9 family
FLQ13_02255	COG4948	Mandelate Racemase Muconate Lactonizing
FLQ13_02260	COG0318	PFAM AMP-dependent synthetase and ligase
FLQ13_02265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FLQ13_02270	COG0596	Alpha beta hydrolase
FLQ13_02275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FLQ13_02280	COG1169	isochorismate synthase
FLQ13_02285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLQ13_02290	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FLQ13_02295	COG0058	SHG alpha-glucan phosphorylase activity
FLQ13_02300	COG0297	glycogen (starch) synthase activity
FLQ13_02305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLQ13_02310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLQ13_02315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FLQ13_02445	COG1247	-acetyltransferase
FLQ13_02450	COG2268	Band 7 protein
FLQ13_02455	COG1585	Membrane protein implicated in regulation of membrane protease activity
FLQ13_02460	COG2318	DinB family
FLQ13_02470	COG1454	alcohol dehydrogenase
FLQ13_02480	COG1510	regulation of RNA biosynthetic process
FLQ13_02490	COG0569	domain protein
FLQ13_02500	COG4682	membrane
FLQ13_02505	COG1705	Flagellar rod assembly protein muramidase FlgJ
FLQ13_02510	COG0477	Major facilitator Superfamily
FLQ13_02530	COG0628	permease
FLQ13_02535	COG0673	inositol 2-dehydrogenase activity
FLQ13_02540	COG4806	L-rhamnose isomerase
FLQ13_02550	COG1070	Carbohydrate kinase
FLQ13_02555	COG1349	DNA-binding transcription factor activity
FLQ13_02560	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_02560	COG3347	Dehydrogenase
FLQ13_02565	COG0840	transmembrane signaling receptor activity
FLQ13_02570	COG0840	transmembrane signaling receptor activity
FLQ13_02575	COG0840	transmembrane signaling receptor activity
FLQ13_02580	COG0840	transmembrane signaling receptor activity
FLQ13_02595	COG2070	2-Nitropropane dioxygenase
FLQ13_02600	COG0432	Pfam Uncharacterised protein family UPF0047
FLQ13_02610	COG0366	Alpha amylase catalytic
FLQ13_02615	COG1253	flavin adenine dinucleotide binding
FLQ13_02620	COG2738	Putative neutral zinc metallopeptidase
FLQ13_02635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FLQ13_02650	COG0166	Belongs to the GPI family
FLQ13_02655	COG1979	alcohol dehydrogenase
FLQ13_02665	COG2155	Conserved Protein
FLQ13_02670	COG1098	S1 RNA binding domain
FLQ13_02680	COG1522	sequence-specific DNA binding
FLQ13_02685	COG2267	carboxylic ester hydrolase activity
FLQ13_02695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FLQ13_02700	COG2205	protein histidine kinase activity
FLQ13_02710	COG5018	Exonuclease
FLQ13_02720	COG2814	Major facilitator Superfamily
FLQ13_02725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLQ13_02730	COG3011	Protein conserved in bacteria
FLQ13_02740	COG3290	protein histidine kinase activity
FLQ13_02745	COG4565	transcriptional regulatory protein
FLQ13_02770	COG3493	citrate carrier protein
FLQ13_02780	COG2111	Na H antiporter
FLQ13_02780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FLQ13_02785	COG2111	Na H antiporter
FLQ13_02790	COG1006	Multisubunit Na H antiporter MnhC subunit
FLQ13_02795	COG0651	ATP synthesis coupled electron transport
FLQ13_02800	COG1863	multisubunit Na H antiporter MnhE subunit
FLQ13_02805	COG2212	antiporter activity
FLQ13_02810	COG1320	monovalent cation:proton antiporter activity
FLQ13_02815	COG2050	protein possibly involved in aromatic compounds catabolism
FLQ13_02820	COG2197	response regulator
FLQ13_02825	COG4585	Histidine kinase
FLQ13_02835	COG0142	geranyltranstransferase activity
FLQ13_02850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FLQ13_02855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FLQ13_02860	COG1335	isochorismatase
FLQ13_02865	COG5506	Protein of unknown function (DUF1694)
FLQ13_02880	COG0628	permease
FLQ13_02900	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_02910	COG1511	domain protein
FLQ13_02920	COG4499	WXG100 protein secretion system (Wss), protein YukC
FLQ13_02925	COG5417	Belongs to the EsaB family
FLQ13_02930	COG4842	Belongs to the WXG100 family
FLQ13_02935	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FLQ13_02935	COG2508	Transcriptional regulator
FLQ13_02940	COG0686	Belongs to the AlaDH PNT family
FLQ13_02945	COG5634	Uncharacterized conserved protein (DUF2278)
FLQ13_02950	COG3251	PFAM MbtH domain protein
FLQ13_02955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLQ13_02960	COG3433	isochorismatase activity
FLQ13_02960	COG1535	isochorismatase
FLQ13_02965	COG1021	2,3-dihydroxybenzoate-AMP ligase
FLQ13_02970	COG1169	isochorismate synthase
FLQ13_02975	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_02980	COG2819	hydrolase of the alpha beta superfamily
FLQ13_02990	COG1268	BioY protein
FLQ13_03000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLQ13_03005	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FLQ13_03010	COG3584	3D domain protein
FLQ13_03025	COG1252	NADH dehydrogenase
FLQ13_03030	COG0492	ferredoxin-NADP+ reductase activity
FLQ13_03040	COG0516	GMP reductase activity
FLQ13_03045	COG0316	Belongs to the HesB IscA family
FLQ13_03050	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FLQ13_03055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLQ13_03060	COG4844	belongs to the
FLQ13_03065	COG1252	NADH dehydrogenase
FLQ13_03070	COG4837	Protein of unknown function (DUF1462)
FLQ13_03075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FLQ13_03080	COG0823	Involved in the tonB-independent uptake of proteins
FLQ13_03080	COG4946	Tricorn protease homolog
FLQ13_03080	COG1506	peptidase
FLQ13_03085	COG0083	homoserine kinase activity
FLQ13_03090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FLQ13_03100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLQ13_03105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FLQ13_03110	COG0647	UMP catabolic process
FLQ13_03135	COG0739	heme binding
FLQ13_03145	COG3377	Domain of unknown function (DUF1805)
FLQ13_03150	COG0737	Belongs to the 5'-nucleotidase family
FLQ13_03155	COG0730	response to heat
FLQ13_03160	COG1801	Protein of unknown function DUF72
FLQ13_03175	COG2508	Transcriptional regulator
FLQ13_03180	COG2233	PERMEase
FLQ13_03185	COG2233	PERMEase
FLQ13_03190	COG3648	Uricase
FLQ13_03190	COG3195	allantoin biosynthetic process
FLQ13_03205	COG2080	2 iron, 2 sulfur cluster binding
FLQ13_03215	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FLQ13_03220	COG2068	MobA-Related Protein
FLQ13_03225	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FLQ13_03235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FLQ13_03245	COG2356	endonuclease I
FLQ13_03250	COG3842	ATPase activity
FLQ13_03255	COG2188	Transcriptional regulator
FLQ13_03260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLQ13_03265	COG0395	ABC-type sugar transport system, permease component
FLQ13_03270	COG1175	transmembrane transport
FLQ13_03275	COG1653	transport
FLQ13_03280	COG2222	sugar isomerase
FLQ13_03285	COG0322	excinuclease ABC activity
FLQ13_03310	COG0719	Fe-S assembly protein
FLQ13_03315	COG0822	iron-sulfur transferase activity
FLQ13_03320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLQ13_03325	COG0719	Fe-S assembly protein
FLQ13_03330	COG0396	ATPase activity
FLQ13_03340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLQ13_03345	COG1464	Belongs to the NlpA lipoprotein family
FLQ13_03350	COG2011	ABC-type metal ion transport system permease component
FLQ13_03355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLQ13_03365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_03370	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FLQ13_03380	COG0509	glycine decarboxylation via glycine cleavage system
FLQ13_03385	COG1393	Belongs to the ArsC family
FLQ13_03390	COG1960	acyl-CoA dehydrogenase activity
FLQ13_03395	COG0183	Belongs to the thiolase family
FLQ13_03420	COG5577	PFAM Coat F domain
FLQ13_03425	COG1846	Transcriptional regulator
FLQ13_03430	COG0477	Major facilitator Superfamily
FLQ13_03435	COG1942	4-Oxalocrotonate Tautomerase
FLQ13_03440	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_03445	COG0583	DNA-binding transcription factor activity
FLQ13_03455	COG1120	ATPase activity
FLQ13_03470	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_03475	COG0783	Belongs to the Dps family
FLQ13_03480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLQ13_03485	COG0745	RESPONSE REGULATOR receiver
FLQ13_03490	COG2205	protein histidine kinase activity
FLQ13_03490	COG2770	Histidine kinase
FLQ13_03500	COG1309	transcriptional regulator
FLQ13_03505	COG0114	fumarate hydratase activity
FLQ13_03530	COG2197	response regulator
FLQ13_03535	COG4585	Histidine kinase
FLQ13_03540	COG4758	membrane
FLQ13_03545	COG3595	metallopeptidase activity
FLQ13_03550	COG1842	Phage shock protein A
FLQ13_03555	COG4758	membrane
FLQ13_03570	COG2096	Adenosyltransferase
FLQ13_03580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLQ13_03585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLQ13_03590	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_03595	COG3386	PFAM SMP-30 Gluconolaconase
FLQ13_03600	COG2205	protein histidine kinase activity
FLQ13_03605	COG0745	RESPONSE REGULATOR receiver
FLQ13_03615	COG1191	sigma factor activity
FLQ13_03625	COG2140	Oxalate decarboxylase
FLQ13_03635	COG0577	efflux transmembrane transporter activity
FLQ13_03640	COG1136	(ABC) transporter
FLQ13_03645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLQ13_03650	COG1120	ATPase activity
FLQ13_03655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLQ13_03660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLQ13_03665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLQ13_03675	COG0531	amino acid
FLQ13_03685	COG1988	membrane-bound metal-dependent
FLQ13_03690	COG1368	sulfuric ester hydrolase activity
FLQ13_03695	COG1910	domain protein
FLQ13_03700	COG0725	ABC transporter, periplasmic molybdate-binding protein
FLQ13_03705	COG4149	molybdate abc transporter
FLQ13_03710	COG0656	L-ascorbic acid biosynthetic process
FLQ13_03720	COG0025	NhaP-type Na H and K H
FLQ13_03725	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLQ13_03745	COG2860	membrane
FLQ13_03755	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FLQ13_03760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLQ13_03765	COG2217	Heavy metal translocating P-type atpase
FLQ13_03770	COG2217	Heavy metal translocating P-type atpase
FLQ13_03775	COG2608	mercury ion transmembrane transporter activity
FLQ13_03780	COG1937	Protein conserved in bacteria
FLQ13_03785	COG0673	inositol 2-dehydrogenase activity
FLQ13_03790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FLQ13_03795	COG1289	transmembrane transporter activity
FLQ13_03800	COG1802	Transcriptional regulator
FLQ13_03805	COG0697	spore germination
FLQ13_03815	COG2076	Multidrug Resistance protein
FLQ13_03820	COG1309	transcriptional regulator
FLQ13_03825	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_03835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FLQ13_03840	COG0557	exoribonuclease II activity
FLQ13_03845	COG1647	Serine aminopeptidase, S33
FLQ13_03850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLQ13_03855	COG0596	Alpha beta hydrolase
FLQ13_03860	COG1476	TRANSCRIPTIONal
FLQ13_03865	COG1396	sequence-specific DNA binding
FLQ13_03870	COG1396	sequence-specific DNA binding
FLQ13_03875	COG1733	regulation of RNA biosynthetic process
FLQ13_03880	COG0840	transmembrane signaling receptor activity
FLQ13_03885	COG1174	glycine betaine transport
FLQ13_03890	COG1732	Glycine betaine
FLQ13_03895	COG1174	glycine betaine transport
FLQ13_03900	COG0517	IMP dehydrogenase activity
FLQ13_03900	COG1125	glycine betaine transport
FLQ13_03905	COG1510	regulation of RNA biosynthetic process
FLQ13_03910	COG1174	glycine betaine transport
FLQ13_03915	COG1732	Glycine betaine
FLQ13_03920	COG1174	glycine betaine transport
FLQ13_03925	COG1125	glycine betaine transport
FLQ13_03925	COG0517	IMP dehydrogenase activity
FLQ13_03930	COG1510	regulation of RNA biosynthetic process
FLQ13_03940	COG3064	Membrane
FLQ13_03945	COG4640	response to antibiotic
FLQ13_03950	COG0456	acetyltransferase
FLQ13_03965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLQ13_03985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLQ13_03990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLQ13_04000	COG2234	aminopeptidase activity
FLQ13_04010	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FLQ13_04015	COG0149	triose-phosphate isomerase activity
FLQ13_04020	COG0126	phosphoglycerate kinase activity
FLQ13_04025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLQ13_04030	COG2390	Transcriptional regulator
FLQ13_04035	COG2814	Major facilitator Superfamily
FLQ13_04040	COG1609	Transcriptional regulator
FLQ13_04045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLQ13_04050	COG0583	DNA-binding transcription factor activity
FLQ13_04055	COG0697	spore germination
FLQ13_04060	COG1113	amino acid transport
FLQ13_04065	COG3858	chitin binding
FLQ13_04070	COG1556	Lactate utilization protein
FLQ13_04075	COG1139	Iron-sulfur cluster binding protein
FLQ13_04080	COG0247	lactate metabolic process
FLQ13_04090	COG2197	response regulator
FLQ13_04095	COG4585	Histidine kinase
FLQ13_04100	COG0842	Transport permease protein
FLQ13_04105	COG1131	(ABC) transporter
FLQ13_04110	COG0596	Alpha beta hydrolase
FLQ13_04115	COG2208	phosphoserine phosphatase activity
FLQ13_04125	COG1874	Beta-galactosidase
FLQ13_04130	COG3833	ABC-type maltose transport systems, permease component
FLQ13_04135	COG1175	transmembrane transport
FLQ13_04140	COG2182	Extracellular solute-binding protein
FLQ13_04145	COG1609	Transcriptional regulator
FLQ13_04150	COG2186	Transcriptional regulator
FLQ13_04155	COG1620	l-lactate permease
FLQ13_04160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FLQ13_04170	COG5039	Polysaccharide pyruvyl transferase
FLQ13_04175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLQ13_04180	COG0110	maltose O-acetyltransferase activity
FLQ13_04185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FLQ13_04190	COG2244	polysaccharide biosynthetic process
FLQ13_04195	COG1216	Glycosyl transferase, family 2
FLQ13_04200	COG5039	Polysaccharide pyruvyl transferase
FLQ13_04205	COG1216	Glycosyl transferase, family 2
FLQ13_04215	COG0438	transferase activity, transferring glycosyl groups
FLQ13_04220	COG1215	transferase activity, transferring glycosyl groups
FLQ13_04225	COG0438	transferase activity, transferring glycosyl groups
FLQ13_04230	COG1086	Polysaccharide biosynthesis protein
FLQ13_04235	COG0489	protein tyrosine kinase activity
FLQ13_04240	COG3944	biosynthesis protein
FLQ13_04245	COG1396	sequence-specific DNA binding
FLQ13_04250	COG2272	Belongs to the type-B carboxylesterase lipase family
FLQ13_04260	COG3479	Phenolic acid decarboxylase
FLQ13_04270	COG1794	racemase activity, acting on amino acids and derivatives
FLQ13_04275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FLQ13_04285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLQ13_04295	COG0640	Transcriptional regulator
FLQ13_04300	COG1621	beta-fructofuranosidase activity
FLQ13_04305	COG1621	beta-fructofuranosidase activity
FLQ13_04310	COG0531	amino acid
FLQ13_04315	COG1309	transcriptional regulator
FLQ13_04320	COG2076	Multidrug Resistance protein
FLQ13_04325	COG2076	Multidrug Resistance protein
FLQ13_04335	COG0277	FAD linked oxidase domain protein
FLQ13_04350	COG1611	Belongs to the LOG family
FLQ13_04355	COG1694	Mazg nucleotide pyrophosphohydrolase
FLQ13_04360	COG0659	secondary active sulfate transmembrane transporter activity
FLQ13_04365	COG0288	reversible hydration of carbon dioxide
FLQ13_04370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLQ13_04375	COG0577	efflux transmembrane transporter activity
FLQ13_04380	COG1136	(ABC) transporter
FLQ13_04385	COG5002	protein histidine kinase activity
FLQ13_04390	COG0745	RESPONSE REGULATOR receiver
FLQ13_04400	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FLQ13_04405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLQ13_04410	COG1481	regulation of sporulation
FLQ13_04420	COG1660	Displays ATPase and GTPase activities
FLQ13_04425	COG1051	belongs to the nudix hydrolase family
FLQ13_04430	COG0492	ferredoxin-NADP+ reductase activity
FLQ13_04435	COG3883	PFAM NLP P60 protein
FLQ13_04435	COG0791	NLP P60 protein
FLQ13_04440	COG0457	Tetratricopeptide repeat
FLQ13_04445	COG1132	(ABC) transporter
FLQ13_04465	COG0140	phosphoribosyl-ATP diphosphatase activity
FLQ13_04465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FLQ13_04470	COG0107	imidazoleglycerol-phosphate synthase activity
FLQ13_04480	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLQ13_04485	COG0131	Imidazoleglycerol-phosphate dehydratase
FLQ13_04490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FLQ13_04495	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FLQ13_04500	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FLQ13_04505	COG4990	cell redox homeostasis
FLQ13_04510	COG5297	Belongs to the glycosyl hydrolase family 6
FLQ13_04515	COG0110	maltose O-acetyltransferase activity
FLQ13_04520	COG0546	phosphoglycolate phosphatase activity
FLQ13_04530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FLQ13_04535	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FLQ13_04540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLQ13_04545	COG0363	glucosamine-6-phosphate deaminase activity
FLQ13_04555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FLQ13_04560	COG1846	Transcriptional regulator
FLQ13_04570	COG1950	PFAM Membrane protein of
FLQ13_04575	COG1983	PspC domain protein
FLQ13_04580	COG3595	metallopeptidase activity
FLQ13_04595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FLQ13_04600	COG0556	nucleotide-excision repair
FLQ13_04605	COG4897	Protein conserved in bacteria
FLQ13_04620	COG2814	Major facilitator Superfamily
FLQ13_04625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLQ13_04635	COG0793	Belongs to the peptidase S41A family
FLQ13_04635	COG3409	Peptidoglycan-binding domain 1 protein
FLQ13_04640	COG2177	Part of the ABC transporter FtsEX involved in
FLQ13_04645	COG2884	Cell division ATP-binding protein ftsE
FLQ13_04650	COG2010	Cytochrome c
FLQ13_04655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLQ13_04665	COG0653	protein targeting
FLQ13_04670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLQ13_04685	COG1516	flagellar protein fliS
FLQ13_04690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FLQ13_04695	COG1334	flagellar protein FlaG
FLQ13_04700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLQ13_04705	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FLQ13_04710	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FLQ13_04720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLQ13_04725	COG1256	bacterial-type flagellum assembly
FLQ13_04725	COG4786	Flagellar basal body rod
FLQ13_04730	COG3418	PFAM FlgN family protein
FLQ13_04735	COG2747	anti-sigma28 factor FlgM
FLQ13_04745	COG1040	competence protein
FLQ13_04755	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FLQ13_04760	COG1307	EDD domain protein, DegV family
FLQ13_04765	COG2197	response regulator
FLQ13_04770	COG4585	Histidine kinase
FLQ13_04775	COG1739	Uncharacterized protein family UPF0029
FLQ13_04780	COG1316	TRANSCRIPTIONal
FLQ13_04785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLQ13_04790	COG0438	transferase activity, transferring glycosyl groups
FLQ13_04795	COG1215	transferase activity, transferring glycosyl groups
FLQ13_04805	COG3307	-O-antigen
FLQ13_04810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLQ13_04815	COG0297	glycogen (starch) synthase activity
FLQ13_04815	COG0438	transferase activity, transferring glycosyl groups
FLQ13_04830	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLQ13_04830	COG2247	cell wall binding repeat
FLQ13_04835	COG2385	sporulation resulting in formation of a cellular spore
FLQ13_04835	COG2247	cell wall binding repeat
FLQ13_04845	COG1316	TRANSCRIPTIONal
FLQ13_04850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FLQ13_04875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLQ13_04880	COG1134	teichoic acid transport
FLQ13_04885	COG1682	transport, permease protein
FLQ13_04890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLQ13_04890	COG1215	transferase activity, transferring glycosyl groups
FLQ13_04895	COG1215	transferase activity, transferring glycosyl groups
FLQ13_04895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLQ13_04900	COG0463	Glycosyl transferase, family 2
FLQ13_04945	COG4193	domain, Protein
FLQ13_04950	COG1482	cell wall glycoprotein biosynthetic process
FLQ13_04955	COG0697	spore germination
FLQ13_04960	COG0814	amino acid
FLQ13_04970	COG2814	Major facilitator Superfamily
FLQ13_04975	COG1316	TRANSCRIPTIONal
FLQ13_04980	COG0561	phosphatase activity
FLQ13_04985	COG0791	NLP P60 protein
FLQ13_04995	COG2843	Capsule synthesis protein
FLQ13_05005	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLQ13_05015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLQ13_05020	COG1869	D-ribose catabolic process
FLQ13_05025	COG1129	ABC transporter
FLQ13_05030	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLQ13_05035	COG1879	ABC-type sugar transport system periplasmic component
FLQ13_05040	COG3103	Sh3 type 3 domain protein
FLQ13_05050	COG2249	NAD(P)H dehydrogenase (quinone) activity
FLQ13_05055	COG3527	Alpha-acetolactate decarboxylase
FLQ13_05060	COG0028	Belongs to the TPP enzyme family
FLQ13_05065	COG0583	DNA-binding transcription factor activity
FLQ13_05070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLQ13_05085	COG5337	Spore coat protein CotH
FLQ13_05095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLQ13_05100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLQ13_05115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLQ13_05125	COG0405	Gamma-glutamyltransferase
FLQ13_05130	COG1522	sequence-specific DNA binding
FLQ13_05135	COG2059	Chromate
FLQ13_05140	COG2059	Chromate
FLQ13_05150	COG0655	NAD(P)H dehydrogenase (quinone) activity
FLQ13_05155	COG0583	DNA-binding transcription factor activity
FLQ13_05195	COG5444	nuclease activity
FLQ13_05220	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLQ13_05225	COG4464	protein tyrosine phosphatase activity
FLQ13_05230	COG0489	protein tyrosine kinase activity
FLQ13_05235	COG3944	biosynthesis protein
FLQ13_05245	COG4715	Zinc finger, swim domain protein
FLQ13_05250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLQ13_05255	COG0561	phosphatase activity
FLQ13_05260	COG1349	DNA-binding transcription factor activity
FLQ13_05265	COG0629	single-stranded DNA binding
FLQ13_05280	COG2602	Beta-lactamase
FLQ13_05285	COG1970	mechanosensitive ion channel activity
FLQ13_05290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FLQ13_05295	COG0457	Tetratricopeptide repeat
FLQ13_05300	COG4786	Flagellar basal body rod
FLQ13_05305	COG4786	Flagellar basal body rod
FLQ13_05310	COG1077	Cell shape determining protein MreB Mrl
FLQ13_05315	COG1609	Transcriptional regulator
FLQ13_05325	COG1846	Transcriptional regulator
FLQ13_05330	COG2814	Major facilitator Superfamily
FLQ13_05335	COG3420	alginic acid biosynthetic process
FLQ13_05340	COG1953	Uracil, thiamine, allantoin
FLQ13_05345	COG0477	Major facilitator Superfamily
FLQ13_05350	COG1335	isochorismatase
FLQ13_05360	COG0004	ammonium transporteR
FLQ13_05365	COG0347	Belongs to the P(II) protein family
FLQ13_05370	COG0671	phosphoesterase, PA-phosphatase related
FLQ13_05380	COG0739	heme binding
FLQ13_05385	COG1247	-acetyltransferase
FLQ13_05410	COG2910	NAD(P)H-binding
FLQ13_05415	COG1959	2 iron, 2 sulfur cluster binding
FLQ13_05425	COG0832	Belongs to the urease beta subunit family
FLQ13_05430	COG0831	urea catabolic process
FLQ13_05460	COG3237	CsbD-like
FLQ13_05465	COG1994	Peptidase M50
FLQ13_05470	COG0457	Tetratricopeptide repeat
FLQ13_05475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FLQ13_05490	COG2304	oxidoreductase activity
FLQ13_05495	COG2304	oxidoreductase activity
FLQ13_05500	COG2385	sporulation resulting in formation of a cellular spore
FLQ13_05510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLQ13_05520	COG4836	Membrane
FLQ13_05530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FLQ13_05535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FLQ13_05540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FLQ13_05550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLQ13_05555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FLQ13_05560	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLQ13_05565	COG0356	it plays a direct role in the translocation of protons across the membrane
FLQ13_05575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FLQ13_05580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FLQ13_05585	COG4475	Protein of unknown function (DUF436)
FLQ13_05590	COG0698	ribose 5-phosphate isomerase
FLQ13_05595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLQ13_05600	COG1971	Probably functions as a manganese efflux pump
FLQ13_05610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FLQ13_05630	COG2890	protein-(glutamine-N5) methyltransferase activity
FLQ13_05635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FLQ13_05640	COG0346	lactoylglutathione lyase activity
FLQ13_05645	COG0789	Transcriptional regulator
FLQ13_05650	COG0679	Auxin Efflux Carrier
FLQ13_05655	COG0281	malic enzyme
FLQ13_05660	COG1435	thymidine kinase activity
FLQ13_05665	COG0254	rRNA binding
FLQ13_05670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FLQ13_05680	COG1494	fructose-1,6-bisphosphatase
FLQ13_05685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLQ13_05690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLQ13_05695	COG0191	fructose-bisphosphate aldolase activity
FLQ13_05700	COG2204	response regulator
FLQ13_05705	COG4821	SIS domain
FLQ13_05710	COG0504	CTP synthase activity
FLQ13_05715	COG3343	RNA polymerase activity
FLQ13_05720	COG1960	acyl-CoA dehydrogenase activity
FLQ13_05725	COG2181	nitrate reductase activity
FLQ13_05725	COG0247	lactate metabolic process
FLQ13_05730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLQ13_05735	COG4294	response to UV
FLQ13_05745	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLQ13_05755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLQ13_05765	COG2181	nitrate reductase activity
FLQ13_05770	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FLQ13_05775	COG1140	nitrate reductase beta subunit
FLQ13_05785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLQ13_05795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLQ13_05800	COG2223	nitrite transmembrane transporter activity
FLQ13_05805	COG0018	arginyl-trna synthetase
FLQ13_05810	COG4506	Protein conserved in bacteria
FLQ13_05825	COG0535	radical SAM domain protein
FLQ13_05835	COG1131	(ABC) transporter
FLQ13_05845	COG0612	Peptidase, M16
FLQ13_05865	COG3391	amine dehydrogenase activity
FLQ13_05875	COG0457	Tetratricopeptide repeat
FLQ13_05885	COG0010	Belongs to the arginase family
FLQ13_05890	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FLQ13_05895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLQ13_05910	COG1994	Peptidase M50
FLQ13_05915	COG1942	4-Oxalocrotonate Tautomerase
FLQ13_05920	COG1846	Transcriptional regulator
FLQ13_05925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLQ13_05930	COG0477	Major facilitator Superfamily
FLQ13_05935	COG1959	2 iron, 2 sulfur cluster binding
FLQ13_05940	COG3465	dGTPase activity
FLQ13_05945	COG1078	dGTPase activity
FLQ13_05950	COG4844	belongs to the
FLQ13_05960	COG0697	spore germination
FLQ13_05965	COG0095	Lipoate-protein ligase
FLQ13_05970	COG0583	DNA-binding transcription factor activity
FLQ13_05975	COG0280	phosphate acetyltransferase
FLQ13_05985	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_05990	COG0436	Aminotransferase
FLQ13_06000	COG0151	Belongs to the GarS family
FLQ13_06005	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_06010	COG1917	Cupin 2, conserved barrel domain protein
FLQ13_06015	COG0077	Prephenate dehydratase
FLQ13_06030	COG0833	amino acid
FLQ13_06035	COG4187	Peptidase family M20/M25/M40
FLQ13_06040	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_06045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLQ13_06055	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FLQ13_06060	COG1091	dTDP-4-dehydrorhamnose reductase activity
FLQ13_06065	COG1088	dTDP-glucose 4,6-dehydratase activity
FLQ13_06070	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FLQ13_06075	COG3980	spore coat polysaccharide biosynthesis protein
FLQ13_06080	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FLQ13_06090	COG0456	acetyltransferase
FLQ13_06100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLQ13_06105	COG0463	Glycosyl transferase, family 2
FLQ13_06115	COG2363	Small membrane protein
FLQ13_06130	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_06135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FLQ13_06140	COG1216	Glycosyl transferase, family 2
FLQ13_06155	COG1695	Transcriptional regulator
FLQ13_06160	COG0351	phosphomethylpyrimidine kinase
FLQ13_06170	COG1621	beta-fructofuranosidase activity
FLQ13_06185	COG3711	transcriptional antiterminator
FLQ13_06195	COG1404	Belongs to the peptidase S8 family
FLQ13_06200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLQ13_06205	COG0778	Nitroreductase
FLQ13_06230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLQ13_06235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FLQ13_06240	COG2261	transglycosylase associated protein
FLQ13_06245	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FLQ13_06250	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FLQ13_06255	COG2246	polysaccharide biosynthetic process
FLQ13_06260	COG1309	transcriptional regulator
FLQ13_06270	COG3162	membrane
FLQ13_06275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLQ13_06280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FLQ13_06290	COG2822	iron ion transport
FLQ13_06295	COG0672	)-iron permease
FLQ13_06300	COG0352	thiamine-phosphate diphosphorylase activity
FLQ13_06305	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FLQ13_06310	COG0583	DNA-binding transcription factor activity
FLQ13_06315	COG1380	Effector of murein hydrolase LrgA
FLQ13_06320	COG1346	cytolysis
FLQ13_06325	COG2814	Major facilitator Superfamily
FLQ13_06330	COG4895	conserved protein (DUF2196)
FLQ13_06340	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FLQ13_06345	COG0346	lactoylglutathione lyase activity
FLQ13_06355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLQ13_06375	COG3711	transcriptional antiterminator
FLQ13_06380	COG1442	glycosyl transferase family 8
FLQ13_06385	COG5522	Integral membrane protein (intg_mem_TP0381)
FLQ13_06390	COG1846	Transcriptional regulator
FLQ13_06395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLQ13_06400	COG2234	aminopeptidase activity
FLQ13_06405	COG2357	RelA SpoT domain protein
FLQ13_06410	COG1575	Belongs to the MenA family. Type 1 subfamily
FLQ13_06420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLQ13_06425	COG1696	Membrane protein involved in D-alanine export
FLQ13_06430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLQ13_06435	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FLQ13_06440	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FLQ13_06445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLQ13_06450	COG1486	melibiose metabolic process
FLQ13_06460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLQ13_06465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLQ13_06470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLQ13_06470	COG3711	transcriptional antiterminator
FLQ13_06480	COG2094	Belongs to the DNA glycosylase MPG family
FLQ13_06485	COG0753	catalase activity
FLQ13_06490	COG2814	Major facilitator Superfamily
FLQ13_06500	COG1131	(ABC) transporter
FLQ13_06520	COG1595	DNA-templated transcription, initiation
FLQ13_06525	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FLQ13_06530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FLQ13_06535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLQ13_06540	COG4988	ABC transporter
FLQ13_06545	COG1294	oxidase, subunit
FLQ13_06550	COG1271	oxidase subunit
FLQ13_06555	COG3493	citrate carrier protein
FLQ13_06560	COG0501	Belongs to the peptidase M48B family
FLQ13_06570	COG0726	polysaccharide deacetylase
FLQ13_06580	COG3842	ATPase activity
FLQ13_06585	COG2508	Transcriptional regulator
FLQ13_06590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLQ13_06615	COG2195	Cleaves the N-terminal amino acid of tripeptides
FLQ13_06625	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FLQ13_06630	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FLQ13_06635	COG3290	protein histidine kinase activity
FLQ13_06635	COG3829	transcription factor binding
FLQ13_06640	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_06645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FLQ13_06650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FLQ13_06655	COG2610	gluconate transmembrane transporter activity
FLQ13_06660	COG0500	methyltransferase
FLQ13_06665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLQ13_06680	COG0693	protein deglycase activity
FLQ13_06680	COG0753	catalase activity
FLQ13_06685	COG2851	Citrate transporter
FLQ13_06695	COG2723	6-phospho-beta-galactosidase activity
FLQ13_06700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_06700	COG2190	(PTS) system
FLQ13_06700	COG1263	PTS System
FLQ13_06705	COG3711	transcriptional antiterminator
FLQ13_06715	COG2270	Major facilitator Superfamily
FLQ13_06720	COG0513	Belongs to the DEAD box helicase family
FLQ13_06725	COG2755	lipolytic protein G-D-S-L family
FLQ13_06725	COG3401	FG-GAP repeat protein
FLQ13_06790	COG0697	spore germination
FLQ13_06795	COG0589	response to stress
FLQ13_06800	COG2723	6-phospho-beta-galactosidase activity
FLQ13_06805	COG2190	(PTS) system
FLQ13_06805	COG1263	PTS System
FLQ13_06805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_06850	COG3507	Belongs to the glycosyl hydrolase 43 family
FLQ13_06865	COG2986	histidine ammonia-lyase
FLQ13_06870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FLQ13_06875	COG1228	amidohydrolase
FLQ13_06885	COG0833	amino acid
FLQ13_06890	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FLQ13_06895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLQ13_06900	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FLQ13_06905	COG2390	Transcriptional regulator
FLQ13_06920	COG2079	MmgE PrpD family protein
FLQ13_06930	COG1126	abc transporter atp-binding protein
FLQ13_06935	COG0765	amino acid transport
FLQ13_06940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLQ13_06960	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FLQ13_06965	COG0561	phosphatase activity
FLQ13_06995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLQ13_07000	COG5294	Protein conserved in bacteria
FLQ13_07010	COG1136	(ABC) transporter
FLQ13_07015	COG2205	protein histidine kinase activity
FLQ13_07020	COG0745	RESPONSE REGULATOR receiver
FLQ13_07035	COG1082	Xylose isomerase domain protein TIM barrel
FLQ13_07040	COG0673	inositol 2-dehydrogenase activity
FLQ13_07045	COG2814	Major facilitator Superfamily
FLQ13_07050	COG1082	Xylose isomerase domain protein TIM barrel
FLQ13_07055	COG3962	Belongs to the TPP enzyme family
FLQ13_07060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLQ13_07070	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_07075	COG1349	DNA-binding transcription factor activity
FLQ13_07080	COG0667	Aldo Keto reductase
FLQ13_07105	COG2814	Major facilitator Superfamily
FLQ13_07110	COG0326	Molecular chaperone. Has ATPase activity
FLQ13_07120	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_07125	COG1309	transcriptional regulator
FLQ13_07130	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_07140	COG0789	Transcriptional regulator
FLQ13_07145	COG1714	RDD family
FLQ13_07150	COG2311	Membrane
FLQ13_07155	COG1917	Cupin 2, conserved barrel domain protein
FLQ13_07160	COG1309	transcriptional regulator
FLQ13_07165	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_07200	COG1929	Belongs to the glycerate kinase type-1 family
FLQ13_07205	COG1802	Transcriptional regulator
FLQ13_07210	COG1070	Carbohydrate kinase
FLQ13_07215	COG2610	gluconate transmembrane transporter activity
FLQ13_07220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLQ13_07225	COG0450	alkyl hydroperoxide reductase
FLQ13_07230	COG3634	alkyl hydroperoxide reductase activity
FLQ13_07235	COG2723	6-phospho-beta-galactosidase activity
FLQ13_07240	COG2190	(PTS) system
FLQ13_07240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_07240	COG1263	PTS System
FLQ13_07245	COG2188	Transcriptional regulator
FLQ13_07255	COG1131	(ABC) transporter
FLQ13_07260	COG1994	Peptidase M50
FLQ13_07275	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FLQ13_07285	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FLQ13_07300	COG1063	alcohol dehydrogenase
FLQ13_07320	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FLQ13_07325	COG0456	acetyltransferase
FLQ13_07330	COG0457	Tetratricopeptide repeat
FLQ13_07340	COG0010	Belongs to the arginase family
FLQ13_07345	COG0833	amino acid
FLQ13_07350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLQ13_07355	COG3829	transcription factor binding
FLQ13_07365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLQ13_07370	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FLQ13_07375	COG4853	Protein conserved in bacteria
FLQ13_07380	COG4863	YycH protein
FLQ13_07385	COG5002	protein histidine kinase activity
FLQ13_07390	COG0745	RESPONSE REGULATOR receiver
FLQ13_07420	COG0346	lactoylglutathione lyase activity
FLQ13_07425	COG0305	Participates in initiation and elongation during chromosome replication
FLQ13_07440	COG3093	addiction module antidote protein HigA
FLQ13_07445	COG2807	transmembrane transport
FLQ13_07455	COG0359	binds to the 23S rRNA
FLQ13_07460	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FLQ13_07475	COG5577	PFAM Coat F domain
FLQ13_07480	COG1733	regulation of RNA biosynthetic process
FLQ13_07485	COG1227	inorganic diphosphatase activity
FLQ13_07500	COG2271	Major facilitator Superfamily
FLQ13_07515	COG4319	ketosteroid isomerase
FLQ13_07520	COG1357	PFAM Pentapeptide repeats (8 copies)
FLQ13_07525	COG2814	Major facilitator Superfamily
FLQ13_07530	COG0583	DNA-binding transcription factor activity
FLQ13_07535	COG2153	protein acetylation
FLQ13_07545	COG0583	DNA-binding transcription factor activity
FLQ13_07560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLQ13_07570	COG0640	Transcriptional regulator
FLQ13_07575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLQ13_07610	COG0300	oxidoreductase activity
FLQ13_07615	COG1902	pentaerythritol trinitrate reductase activity
FLQ13_07620	COG0596	Alpha beta hydrolase
FLQ13_07620	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLQ13_07625	COG1309	transcriptional regulator
FLQ13_07635	COG1063	alcohol dehydrogenase
FLQ13_07650	COG0789	Transcriptional regulator
FLQ13_07650	COG4978	Transcriptional regulator
FLQ13_07655	COG1811	Na channel or pump
FLQ13_07660	COG3708	Transcriptional regulator
FLQ13_07660	COG2207	Transcriptional regulator
FLQ13_07680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLQ13_07685	COG1331	Highly conserved protein containing a thioredoxin domain
FLQ13_07705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLQ13_07710	COG2856	Zn peptidase
FLQ13_07745	COG1331	Highly conserved protein containing a thioredoxin domain
FLQ13_07750	COG1266	CAAX protease self-immunity
FLQ13_07755	COG2814	Major facilitator Superfamily
FLQ13_07755	COG0477	Major facilitator Superfamily
FLQ13_07760	COG0110	maltose O-acetyltransferase activity
FLQ13_07765	COG0346	lactoylglutathione lyase activity
FLQ13_07770	COG1609	Transcriptional regulator
FLQ13_07775	COG0708	Exodeoxyribonuclease III
FLQ13_07790	COG0360	Binds together with S18 to 16S ribosomal RNA
FLQ13_07795	COG0012	GTP binding
FLQ13_07800	COG0243	molybdopterin cofactor binding
FLQ13_07805	COG4481	Protein conserved in bacteria
FLQ13_07810	COG3949	Membrane
FLQ13_07820	COG1475	DNA binding
FLQ13_07825	COG1192	Involved in chromosome partitioning
FLQ13_07835	COG1475	DNA binding
FLQ13_07840	COG0357	Ribosomal RNA small subunit methyltransferase G
FLQ13_07845	COG0445	tRNA wobble uridine modification
FLQ13_07850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FLQ13_07855	COG1847	R3H domain protein
FLQ13_07860	COG0706	membrane insertase activity
FLQ13_07865	COG0594	ribonuclease P activity
FLQ13_07870	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FLQ13_07875	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FLQ13_07880	COG0592	DNA-directed DNA polymerase activity
FLQ13_07885	COG2501	S4 domain
FLQ13_07890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLQ13_07900	COG0187	DNA topoisomerase II activity
FLQ13_07910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLQ13_07945	COG0516	GMP reductase activity
FLQ13_07945	COG0517	IMP dehydrogenase activity
FLQ13_07950	COG1686	Belongs to the peptidase S11 family
FLQ13_07955	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FLQ13_07960	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FLQ13_07965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FLQ13_07975	COG1428	Deoxynucleoside kinase
FLQ13_07980	COG1428	Deoxynucleoside kinase
FLQ13_07985	COG1388	LysM domain
FLQ13_07985	COG3858	chitin binding
FLQ13_07990	COG1335	isochorismatase
FLQ13_07995	COG0590	tRNA wobble adenosine to inosine editing
FLQ13_08005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FLQ13_08010	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FLQ13_08015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FLQ13_08060	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FLQ13_08065	COG3853	Toxic anion resistance protein (TelA)
FLQ13_08070	COG1982	Orn Lys Arg decarboxylase major
FLQ13_08080	COG3870	Protein conserved in bacteria
FLQ13_08085	COG1728	Protein conserved in bacteria
FLQ13_08090	COG0470	DNA polymerase III
FLQ13_08095	COG1774	PSP1 C-terminal conserved region
FLQ13_08105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FLQ13_08110	COG2827	Endonuclease containing a URI domain
FLQ13_08115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FLQ13_08120	COG2002	toxin-antitoxin pair type II binding
FLQ13_08125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLQ13_08125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLQ13_08130	COG0084	hydrolase, TatD family'
FLQ13_08135	COG3583	domain protein
FLQ13_08135	COG3584	3D domain protein
FLQ13_08140	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FLQ13_08145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FLQ13_08155	COG4466	Protein conserved in bacteria
FLQ13_08165	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FLQ13_08170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLQ13_08175	COG0251	oxidation-reduction process
FLQ13_08180	COG2088	sporulation resulting in formation of a cellular spore
FLQ13_08185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLQ13_08190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLQ13_08195	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FLQ13_08200	COG0193	aminoacyl-tRNA hydrolase activity
FLQ13_08210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLQ13_08215	COG2002	toxin-antitoxin pair type II binding
FLQ13_08225	COG3956	TIGRFAM MazG family protein
FLQ13_08230	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FLQ13_08245	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FLQ13_08250	COG1098	S1 RNA binding domain
FLQ13_08265	COG2208	phosphoserine phosphatase activity
FLQ13_08270	COG2304	oxidoreductase activity
FLQ13_08275	COG0515	serine threonine protein kinase
FLQ13_08280	COG0037	tRNA processing
FLQ13_08290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLQ13_08295	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FLQ13_08300	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FLQ13_08310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLQ13_08315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLQ13_08320	COG0512	Glutamine amidotransferase of anthranilate synthase
FLQ13_08325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLQ13_08330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FLQ13_08335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLQ13_08340	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FLQ13_08345	COG1396	sequence-specific DNA binding
FLQ13_08350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLQ13_08355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FLQ13_08435	COG4463	regulation of RNA biosynthetic process
FLQ13_08440	COG3880	PFAM UvrB UvrC protein
FLQ13_08445	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FLQ13_08450	COG0542	response to heat
FLQ13_08455	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FLQ13_08460	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FLQ13_08465	COG4956	integral membrane protein (PIN domain superfamily)
FLQ13_08470	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FLQ13_08475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FLQ13_08480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLQ13_08485	COG1045	serine acetyltransferase
FLQ13_08495	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FLQ13_08500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLQ13_08505	COG3688	RNA-binding protein containing a PIN domain
FLQ13_08510	COG1595	DNA-templated transcription, initiation
FLQ13_08515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FLQ13_08520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLQ13_08525	COG0250	Participates in transcription elongation, termination and antitermination
FLQ13_08530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FLQ13_08535	COG0081	regulation of translation
FLQ13_08545	COG0222	ribosome binding
FLQ13_08550	COG2813	Specifically methylates the guanine in position
FLQ13_08555	COG0085	RNA polymerase activity
FLQ13_08560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLQ13_08565	COG1358	cellular component organization or biogenesis
FLQ13_08575	COG0049	tRNA binding
FLQ13_08580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FLQ13_08585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLQ13_08590	COG0596	Alpha beta hydrolase
FLQ13_08595	COG0051	transcription antitermination factor activity, RNA binding
FLQ13_08600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FLQ13_08610	COG0089	rRNA binding
FLQ13_08615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FLQ13_08620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLQ13_08625	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FLQ13_08630	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FLQ13_08635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FLQ13_08640	COG0255	Belongs to the universal ribosomal protein uL29 family
FLQ13_08645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FLQ13_08650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FLQ13_08660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FLQ13_08670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FLQ13_08675	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FLQ13_08680	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FLQ13_08690	COG1841	ribosomal large subunit assembly
FLQ13_08695	COG0200	Binds to the 23S rRNA
FLQ13_08700	COG0201	protein transport
FLQ13_08705	COG0563	adenylate kinase activity
FLQ13_08710	COG0024	Methionine aminopeptidase
FLQ13_08720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FLQ13_08725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FLQ13_08735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FLQ13_08740	COG0202	RNA polymerase activity
FLQ13_08745	COG0203	ribosomal protein L17
FLQ13_08750	COG1122	ATPase activity
FLQ13_08755	COG1122	ATPase activity
FLQ13_08760	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLQ13_08765	COG0101	tRNA pseudouridine synthase activity
FLQ13_08770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FLQ13_08780	COG2226	methyltransferase
FLQ13_08790	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLQ13_08795	COG0489	protein tyrosine kinase activity
FLQ13_08805	COG2194	sulfuric ester hydrolase activity
FLQ13_08810	COG0726	polysaccharide deacetylase
FLQ13_08895	COG0659	secondary active sulfate transmembrane transporter activity
FLQ13_08900	COG0385	Bile acid
FLQ13_08905	COG2819	hydrolase of the alpha beta superfamily
FLQ13_08910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLQ13_08915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLQ13_08920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLQ13_08925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLQ13_08925	COG2207	Transcriptional regulator
FLQ13_08930	COG3876	Protein conserved in bacteria
FLQ13_08935	COG1472	Belongs to the glycosyl hydrolase 3 family
FLQ13_08940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FLQ13_08945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_08945	COG1263	PTS System
FLQ13_08950	COG1737	Transcriptional regulator
FLQ13_08955	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FLQ13_08960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLQ13_08965	COG1683	Conserved Protein
FLQ13_08995	COG1595	DNA-templated transcription, initiation
FLQ13_09000	COG5662	AntiSigma factor
FLQ13_09005	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FLQ13_09010	COG4856	YbbR-like protein
FLQ13_09015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLQ13_09040	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FLQ13_09045	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FLQ13_09055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FLQ13_09065	COG0288	reversible hydration of carbon dioxide
FLQ13_09075	COG5609	conserved protein (DUF2294)
FLQ13_09080	COG0640	Transcriptional regulator
FLQ13_09085	COG2814	Major facilitator Superfamily
FLQ13_09090	COG1413	lyase activity
FLQ13_09100	COG0596	Alpha beta hydrolase
FLQ13_09105	COG0745	RESPONSE REGULATOR receiver
FLQ13_09110	COG0642	Histidine kinase
FLQ13_09120	COG0515	serine threonine protein kinase
FLQ13_09135	COG1113	amino acid transport
FLQ13_09150	COG2602	Beta-lactamase
FLQ13_09165	COG0531	amino acid
FLQ13_09175	COG0584	glycerophosphoryl diester phosphodiesterase
FLQ13_09195	COG1846	Transcriptional regulator
FLQ13_09195	COG0456	acetyltransferase
FLQ13_09200	COG2271	Major facilitator Superfamily
FLQ13_09210	COG3409	Peptidoglycan-binding domain 1 protein
FLQ13_09215	COG0697	spore germination
FLQ13_09225	COG0371	Dehydrogenase
FLQ13_09230	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FLQ13_09235	COG3591	Belongs to the peptidase S1B family
FLQ13_09250	COG1183	phosphatidylcholine synthase activity
FLQ13_09255	COG0586	Pfam SNARE associated Golgi protein
FLQ13_09260	COG0688	phosphatidylethanolamine metabolic process
FLQ13_09270	COG2312	Erythromycin esterase
FLQ13_09280	COG1301	dicarboxylic acid transport
FLQ13_09285	COG2190	(PTS) system
FLQ13_09285	COG1263	PTS System
FLQ13_09285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_09305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLQ13_09310	COG0833	amino acid
FLQ13_09315	COG2040	homocysteine
FLQ13_09320	COG1115	amino acid carrier protein
FLQ13_09325	COG2066	Belongs to the glutaminase family
FLQ13_09335	COG0784	Response regulator, receiver
FLQ13_09350	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_09355	COG2271	Major facilitator Superfamily
FLQ13_09360	COG4948	Mandelate Racemase Muconate Lactonizing
FLQ13_09365	COG2186	Transcriptional regulator
FLQ13_09375	COG3173	Aminoglycoside phosphotransferase
FLQ13_09390	COG2205	protein histidine kinase activity
FLQ13_09415	COG3773	Cell wall hydrolase
FLQ13_09420	COG2304	oxidoreductase activity
FLQ13_09430	COG3540	Alkaline phosphatase
FLQ13_09435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLQ13_09445	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FLQ13_09455	COG0477	Major facilitator Superfamily
FLQ13_09460	COG1309	transcriptional regulator
FLQ13_09465	COG0252	asparaginase activity
FLQ13_09475	COG1714	RDD family
FLQ13_09480	COG1405	negative regulation of cell septum assembly
FLQ13_09480	COG3012	SEC-C Motif Domain Protein
FLQ13_09485	COG3290	protein histidine kinase activity
FLQ13_09490	COG3279	Response regulator of the LytR AlgR family
FLQ13_09495	COG4555	ABC transporter
FLQ13_09500	COG1668	transmembrane transport
FLQ13_09505	COG0667	Aldo Keto reductase
FLQ13_09520	COG1595	DNA-templated transcription, initiation
FLQ13_09525	COG1595	DNA-templated transcription, initiation
FLQ13_09530	COG1876	peptidase activity
FLQ13_09535	COG0457	Tetratricopeptide repeat
FLQ13_09540	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_09545	COG0366	Alpha amylase catalytic
FLQ13_09550	COG0803	Belongs to the bacterial solute-binding protein 9 family
FLQ13_09555	COG1121	(ABC) transporter
FLQ13_09560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLQ13_09565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLQ13_09570	COG2310	stress, protein
FLQ13_09575	COG2310	stress, protein
FLQ13_09580	COG2310	stress, protein
FLQ13_09585	COG0861	Integral membrane protein TerC family
FLQ13_09600	COG1358	cellular component organization or biogenesis
FLQ13_09615	COG3853	Toxic anion resistance protein (TelA)
FLQ13_09620	COG0477	Major facilitator Superfamily
FLQ13_09625	COG2814	Major facilitator Superfamily
FLQ13_09630	COG0640	Transcriptional regulator
FLQ13_09635	COG4175	Glycine betaine
FLQ13_09635	COG0517	IMP dehydrogenase activity
FLQ13_09640	COG4176	ABC-type proline glycine betaine transport system permease component
FLQ13_09645	COG2113	Glycine betaine
FLQ13_09650	COG1473	amidohydrolase
FLQ13_09655	COG1288	antiporter activity
FLQ13_09670	COG0039	L-malate dehydrogenase activity
FLQ13_09675	COG1620	l-lactate permease
FLQ13_09680	COG2814	Major facilitator Superfamily
FLQ13_09685	COG1846	Transcriptional regulator
FLQ13_09690	COG1280	lysine exporter protein (LysE YggA)
FLQ13_09695	COG3403	YqcI/YcgG family
FLQ13_09700	COG1113	amino acid transport
FLQ13_09705	COG3665	Urea carboxylase-associated protein
FLQ13_09710	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FLQ13_09715	COG1660	Displays ATPase and GTPase activities
FLQ13_09725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLQ13_09735	COG2226	methyltransferase
FLQ13_09740	COG0583	DNA-binding transcription factor activity
FLQ13_09745	COG3458	cephalosporin-C deacetylase activity
FLQ13_09750	COG3541	Predicted nucleotidyltransferase
FLQ13_09760	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_09765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLQ13_09770	COG2508	Transcriptional regulator
FLQ13_09775	COG3689	TIGRFAM TIGR03943 family protein
FLQ13_09780	COG0701	Predicted permease
FLQ13_09785	COG0492	ferredoxin-NADP+ reductase activity
FLQ13_09790	COG1587	Uroporphyrinogen-III synthase
FLQ13_09790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FLQ13_09795	COG2146	nitrite reductase [NAD(P)H] activity
FLQ13_09800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLQ13_09820	COG1469	GTP cyclohydrolase I activity
FLQ13_09825	COG1376	ErfK ybiS ycfS ynhG family protein
FLQ13_09835	COG0523	cobalamin synthesis protein
FLQ13_09840	COG0765	amino acid transport
FLQ13_09845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLQ13_09850	COG1063	alcohol dehydrogenase
FLQ13_09870	COG2723	6-phospho-beta-galactosidase activity
FLQ13_09880	COG3209	COG3209 Rhs family protein
FLQ13_09885	COG0840	transmembrane signaling receptor activity
FLQ13_09885	COG3290	protein histidine kinase activity
FLQ13_09890	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FLQ13_09900	COG1733	regulation of RNA biosynthetic process
FLQ13_09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLQ13_09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLQ13_09915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLQ13_09920	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FLQ13_09935	COG0697	spore germination
FLQ13_09945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLQ13_09960	COG1126	abc transporter atp-binding protein
FLQ13_09965	COG0765	amino acid transport
FLQ13_09970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLQ13_09975	COG0583	DNA-binding transcription factor activity
FLQ13_09980	COG0163	prenyltransferase activity
FLQ13_09985	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FLQ13_10000	COG0596	Alpha beta hydrolase
FLQ13_10005	COG3104	oligopeptide transport
FLQ13_10010	COG5434	Belongs to the glycosyl hydrolase 28 family
FLQ13_10020	COG0697	spore germination
FLQ13_10030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FLQ13_10035	COG1136	(ABC) transporter
FLQ13_10040	COG0577	efflux transmembrane transporter activity
FLQ13_10045	COG0745	RESPONSE REGULATOR receiver
FLQ13_10050	COG5002	protein histidine kinase activity
FLQ13_10050	COG3850	Histidine kinase
FLQ13_10055	COG0457	Tetratricopeptide repeat
FLQ13_10075	COG0527	aspartate kinase activity
FLQ13_10080	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLQ13_10085	COG4605	iron ion homeostasis
FLQ13_10095	COG4607	ABC-type enterochelin transport system periplasmic component
FLQ13_10100	COG2814	Major facilitator Superfamily
FLQ13_10105	COG1309	transcriptional regulator
FLQ13_10110	COG0778	Nitroreductase
FLQ13_10115	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FLQ13_10120	COG0640	Transcriptional regulator
FLQ13_10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLQ13_10130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLQ13_10135	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_10145	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_10150	COG4549	nuclear export factor GLE1
FLQ13_10155	COG2372	response to copper ion
FLQ13_10155	COG1276	copper resistance
FLQ13_10160	COG1349	DNA-binding transcription factor activity
FLQ13_10175	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLQ13_10180	COG0246	Mannitol dehydrogenase
FLQ13_10185	COG0473	3-isopropylmalate dehydrogenase activity
FLQ13_10190	COG0412	Dienelactone hydrolase
FLQ13_10195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FLQ13_10205	COG0561	phosphatase activity
FLQ13_10210	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FLQ13_10220	COG4336	lyase activity
FLQ13_10225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FLQ13_10230	COG1984	allophanate hydrolase subunit 2
FLQ13_10250	COG2329	Antibiotic biosynthesis monooxygenase
FLQ13_10260	COG4989	oxidoreductase activity
FLQ13_10265	COG3711	transcriptional antiterminator
FLQ13_10270	COG0318	PFAM AMP-dependent synthetase and ligase
FLQ13_10275	COG2226	methyltransferase
FLQ13_10280	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_10285	COG1917	Cupin 2, conserved barrel domain protein
FLQ13_10290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLQ13_10295	COG3871	stress protein (general stress protein 26)
FLQ13_10305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLQ13_10310	COG2814	Major facilitator Superfamily
FLQ13_10315	COG1522	sequence-specific DNA binding
FLQ13_10320	COG0551	DNA topoisomerase type I activity
FLQ13_10320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLQ13_10330	COG3706	GGDEF domain
FLQ13_10335	COG5298	Protein conserved in bacteria
FLQ13_10360	COG0028	Belongs to the TPP enzyme family
FLQ13_10370	COG1914	H( )-stimulated, divalent metal cation uptake system
FLQ13_10375	COG2261	transglycosylase associated protein
FLQ13_10380	COG4876	unkown
FLQ13_10385	COG2217	Heavy metal translocating P-type atpase
FLQ13_10390	COG3729	General stress protein
FLQ13_10395	COG0662	Cupin 2, conserved barrel domain protein
FLQ13_10410	COG3546	catalase activity
FLQ13_10415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FLQ13_10420	COG3290	protein histidine kinase activity
FLQ13_10425	COG4565	transcriptional regulatory protein
FLQ13_10430	COG1301	dicarboxylic acid transport
FLQ13_10435	COG0628	permease
FLQ13_10440	COG1301	dicarboxylic acid transport
FLQ13_10445	COG1131	(ABC) transporter
FLQ13_10450	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FLQ13_10460	COG1960	acyl-CoA dehydrogenase activity
FLQ13_10475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLQ13_10480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_10485	COG1181	Belongs to the D-alanine--D-alanine ligase family
FLQ13_10490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FLQ13_10495	COG0513	Belongs to the DEAD box helicase family
FLQ13_10500	COG3402	PFAM membrane-flanked domain
FLQ13_10510	COG0705	Rhomboid family
FLQ13_10515	COG0736	holo-[acyl-carrier-protein] synthase activity
FLQ13_10520	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FLQ13_10525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLQ13_10530	COG0864	Transcriptional regulator
FLQ13_10535	COG2337	Toxic component of a toxin-antitoxin (TA) module
FLQ13_10540	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_10545	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_10550	COG2172	sigma factor antagonist activity
FLQ13_10555	COG2208	phosphoserine phosphatase activity
FLQ13_10560	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_10565	COG2172	sigma factor antagonist activity
FLQ13_10570	COG1191	sigma factor activity
FLQ13_10575	COG2208	phosphoserine phosphatase activity
FLQ13_10585	COG1673	EVE domain
FLQ13_10590	COG1846	Transcriptional regulator
FLQ13_10595	COG2183	response to ionizing radiation
FLQ13_10605	COG3091	SprT-like family
FLQ13_10670	COG0697	spore germination
FLQ13_10740	COG0604	alcohol dehydrogenase
FLQ13_10750	COG3239	Fatty acid desaturase
FLQ13_10755	COG1278	Cold shock
FLQ13_10760	COG1278	Cold shock
FLQ13_10765	COG1329	Transcriptional regulator
FLQ13_10770	COG2315	Protein conserved in bacteria
FLQ13_10775	COG0346	lactoylglutathione lyase activity
FLQ13_10800	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FLQ13_10815	COG2364	Membrane
FLQ13_10820	COG1846	Transcriptional regulator
FLQ13_10825	COG0456	acetyltransferase
FLQ13_10830	COG2808	Putative FMN-binding domain
FLQ13_10840	COG0697	spore germination
FLQ13_10845	COG0693	protein deglycase activity
FLQ13_10850	COG0789	Transcriptional regulator
FLQ13_10850	COG4978	Transcriptional regulator
FLQ13_10865	COG0697	spore germination
FLQ13_10870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLQ13_10875	COG0640	Transcriptional regulator
FLQ13_10880	COG0346	lactoylglutathione lyase activity
FLQ13_10890	COG3764	Sortase (surface protein transpeptidase)
FLQ13_10910	COG0456	acetyltransferase
FLQ13_10920	COG0702	epimerase
FLQ13_10930	COG3711	transcriptional antiterminator
FLQ13_10930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLQ13_10935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLQ13_10935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLQ13_10935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLQ13_10940	COG1482	cell wall glycoprotein biosynthetic process
FLQ13_10945	COG2030	dehydratase
FLQ13_10950	COG0697	spore germination
FLQ13_10960	COG0596	Alpha beta hydrolase
FLQ13_10980	COG0778	Nitroreductase
FLQ13_10985	COG0346	lactoylglutathione lyase activity
FLQ13_10990	COG2259	Doxx family
FLQ13_10995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_11000	COG1309	transcriptional regulator
FLQ13_11010	COG0456	acetyltransferase
FLQ13_11020	COG0673	inositol 2-dehydrogenase activity
FLQ13_11025	COG1609	Transcriptional regulator
FLQ13_11045	COG1113	amino acid transport
FLQ13_11050	COG2318	DinB family
FLQ13_11055	COG1846	Transcriptional regulator
FLQ13_11060	COG2409	Drug exporters of the RND superfamily
FLQ13_11060	COG1033	growth of symbiont in host cell
FLQ13_11070	COG0778	Nitroreductase
FLQ13_11075	COG1846	Transcriptional regulator
FLQ13_11080	COG1396	sequence-specific DNA binding
FLQ13_11085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FLQ13_11100	COG2814	Major facilitator Superfamily
FLQ13_11110	COG1802	Transcriptional regulator
FLQ13_11115	COG1388	LysM domain
FLQ13_11115	COG3858	chitin binding
FLQ13_11135	COG1785	Belongs to the alkaline phosphatase family
FLQ13_11145	COG1388	LysM domain
FLQ13_11150	COG2814	Major facilitator Superfamily
FLQ13_11155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLQ13_11160	COG1447	Phosphotransferase system cellobiose-specific component IIA
FLQ13_11165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLQ13_11170	COG2723	6-phospho-beta-galactosidase activity
FLQ13_11175	COG2188	Transcriptional regulator
FLQ13_11180	COG1940	carbohydrate kinase activity
FLQ13_11185	COG1482	cell wall glycoprotein biosynthetic process
FLQ13_11190	COG4124	Belongs to the glycosyl hydrolase 26 family
FLQ13_11235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FLQ13_11240	COG0802	atpase or kinase
FLQ13_11245	COG1214	PFAM Peptidase M22, glycoprotease
FLQ13_11250	COG0456	acetyltransferase
FLQ13_11255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FLQ13_11260	COG0488	(ABC) transporter
FLQ13_11265	COG0315	cyclic pyranopterin monophosphate synthase activity
FLQ13_11270	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FLQ13_11275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLQ13_11280	COG0805	protein transport
FLQ13_11290	COG1266	CAAX protease self-immunity
FLQ13_11295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FLQ13_11310	COG1073	alpha beta
FLQ13_11315	COG0457	Tetratricopeptide repeat
FLQ13_11320	COG1063	alcohol dehydrogenase
FLQ13_11325	COG2211	Major facilitator Superfamily
FLQ13_11330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLQ13_11335	COG1842	Phage shock protein A
FLQ13_11340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLQ13_11345	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FLQ13_11350	COG4260	virion core protein, lumpy skin disease virus
FLQ13_11360	COG2814	Major facilitator Superfamily
FLQ13_11365	COG1063	alcohol dehydrogenase
FLQ13_11370	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FLQ13_11385	COG2267	carboxylic ester hydrolase activity
FLQ13_11400	COG1113	amino acid transport
FLQ13_11410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLQ13_11415	COG0714	Associated with various cellular activities
FLQ13_11420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FLQ13_11425	COG1305	Transglutaminase-like
FLQ13_11430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FLQ13_11430	COG0519	Catalyzes the synthesis of GMP from XMP
FLQ13_11445	COG2252	PERMEase
FLQ13_11455	COG3064	Membrane
FLQ13_11465	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FLQ13_11475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLQ13_11480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLQ13_11485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLQ13_11490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FLQ13_11495	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLQ13_11500	COG0047	phosphoribosylformylglycinamidine synthase activity
FLQ13_11510	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLQ13_11515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FLQ13_11520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLQ13_11525	COG0138	bifunctional purine biosynthesis protein purh
FLQ13_11530	COG0151	Belongs to the GarS family
FLQ13_11540	COG1522	sequence-specific DNA binding
FLQ13_11545	COG0531	amino acid
FLQ13_11555	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FLQ13_11560	COG1470	cell adhesion involved in biofilm formation
FLQ13_11565	COG4496	protein, YerC YecD
FLQ13_11570	COG0069	glutamate synthase activity
FLQ13_11580	COG0210	DNA helicase
FLQ13_11585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FLQ13_11595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLQ13_11600	COG1285	pathogenesis
FLQ13_11605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLQ13_11610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLQ13_11615	COG0154	amidase activity
FLQ13_11620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLQ13_11625	COG1309	transcriptional regulator
FLQ13_11630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLQ13_11635	COG1597	lipid kinase activity
FLQ13_11640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLQ13_11650	COG0457	Tetratricopeptide repeat
FLQ13_11675	COG5444	nuclease activity
FLQ13_11680	COG3391	amine dehydrogenase activity
FLQ13_11695	COG0457	Tetratricopeptide repeat
FLQ13_11705	COG0217	transcriptional regulatory protein
FLQ13_11715	COG1309	transcriptional regulator
FLQ13_11720	COG3631	Ketosteroid isomerase-related protein
FLQ13_11725	COG0702	epimerase
FLQ13_11730	COG2159	amidohydrolase
FLQ13_11735	COG1309	transcriptional regulator
FLQ13_11750	COG3546	catalase activity
FLQ13_11755	COG0454	-acetyltransferase
FLQ13_11765	COG5578	integral membrane protein
FLQ13_11770	COG2972	Histidine kinase
FLQ13_11775	COG2207	Transcriptional regulator
FLQ13_11775	COG4753	response regulator
FLQ13_11780	COG1653	transport
FLQ13_11785	COG1175	transmembrane transport
FLQ13_11790	COG0395	ABC-type sugar transport system, permease component
FLQ13_11795	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FLQ13_11805	COG2755	lipolytic protein G-D-S-L family
FLQ13_11815	COG5578	integral membrane protein
FLQ13_11820	COG3401	FG-GAP repeat protein
FLQ13_11825	COG3401	FG-GAP repeat protein
FLQ13_11830	COG0667	Aldo Keto reductase
FLQ13_11835	COG2755	lipolytic protein G-D-S-L family
FLQ13_11850	COG1653	transport
FLQ13_11855	COG4209	transmembrane transport
FLQ13_11860	COG0395	ABC-type sugar transport system, permease component
FLQ13_11870	COG2323	membrane
FLQ13_11875	COG2329	Antibiotic biosynthesis monooxygenase
FLQ13_11880	COG0346	lactoylglutathione lyase activity
FLQ13_11895	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_11900	COG5583	Uncharacterized small protein (DUF2292)
FLQ13_11905	COG0670	Belongs to the BI1 family
FLQ13_11910	COG1846	Transcriptional regulator
FLQ13_11925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FLQ13_11925	COG2124	cytochrome p450
FLQ13_11930	COG1368	sulfuric ester hydrolase activity
FLQ13_11935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FLQ13_11940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLQ13_11945	COG1442	glycosyl transferase family 8
FLQ13_11950	COG1216	Glycosyl transferase, family 2
FLQ13_11955	COG1442	glycosyl transferase family 8
FLQ13_11960	COG2223	nitrite transmembrane transporter activity
FLQ13_11965	COG1011	Hydrolase
FLQ13_11970	COG0531	amino acid
FLQ13_11975	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_11980	COG0840	transmembrane signaling receptor activity
FLQ13_11985	COG0488	(ABC) transporter
FLQ13_11995	COG0789	Transcriptional regulator
FLQ13_12000	COG2814	Major facilitator Superfamily
FLQ13_12010	COG0488	(ABC) transporter
FLQ13_12015	COG0513	Belongs to the DEAD box helicase family
FLQ13_12020	COG0456	acetyltransferase
FLQ13_12025	COG2130	NADP-dependent
FLQ13_12035	COG2211	Major facilitator Superfamily
FLQ13_12040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FLQ13_12045	COG1120	ATPase activity
FLQ13_12055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLQ13_12060	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FLQ13_12075	COG3866	Pectate lyase
FLQ13_12080	COG0471	metal ion transport
FLQ13_12105	COG0463	Glycosyl transferase, family 2
FLQ13_12115	COG3290	protein histidine kinase activity
FLQ13_12120	COG4565	transcriptional regulatory protein
FLQ13_12125	COG3181	Tripartite tricarboxylate transporter family receptor
FLQ13_12130	COG2851	Citrate transporter
FLQ13_12135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLQ13_12140	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FLQ13_12145	COG1254	Belongs to the acylphosphatase family
FLQ13_12150	COG2258	MOSC domain
FLQ13_12170	COG0024	Methionine aminopeptidase
FLQ13_12175	COG1263	PTS System
FLQ13_12175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_12180	COG1368	sulfuric ester hydrolase activity
FLQ13_12195	COG1263	PTS System
FLQ13_12195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_12205	COG2188	Transcriptional regulator
FLQ13_12210	COG0778	Nitroreductase
FLQ13_12220	COG0737	Belongs to the 5'-nucleotidase family
FLQ13_12225	COG0693	protein deglycase activity
FLQ13_12230	COG2814	Major facilitator Superfamily
FLQ13_12235	COG4840	Belongs to the UPF0435 family
FLQ13_12240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLQ13_12245	COG4980	gas vesicle protein
FLQ13_12275	COG0535	radical SAM domain protein
FLQ13_12285	COG0726	polysaccharide deacetylase
FLQ13_12295	COG2084	Dehydrogenase
FLQ13_12300	COG0598	Magnesium transport protein CorA
FLQ13_12305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FLQ13_12310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLQ13_12320	COG1132	(ABC) transporter
FLQ13_12325	COG0515	serine threonine protein kinase
FLQ13_12335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLQ13_12345	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FLQ13_12360	COG4637	Psort location Cytoplasmic, score
FLQ13_12370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLQ13_12375	COG0022	dehydrogenase e1 component
FLQ13_12380	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLQ13_12385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLQ13_12390	COG3284	Transcriptional regulator
FLQ13_12400	COG1742	UPF0060 membrane protein
FLQ13_12425	COG4842	Belongs to the WXG100 family
FLQ13_12430	COG1486	melibiose metabolic process
FLQ13_12435	COG1737	Transcriptional regulator
FLQ13_12445	COG1132	(ABC) transporter
FLQ13_12450	COG1132	(ABC) transporter
FLQ13_12455	COG2259	Doxx family
FLQ13_12460	COG2514	catechol 2,3-dioxygenase activity
FLQ13_12465	COG4977	sequence-specific DNA binding
FLQ13_12465	COG1917	Cupin 2, conserved barrel domain protein
FLQ13_12475	COG1082	Xylose isomerase domain protein TIM barrel
FLQ13_12480	COG0673	inositol 2-dehydrogenase activity
FLQ13_12485	COG4585	Histidine kinase
FLQ13_12490	COG2197	response regulator
FLQ13_12495	COG1131	(ABC) transporter
FLQ13_12500	COG0842	Transport permease protein
FLQ13_12500	COG1511	domain protein
FLQ13_12505	COG0842	Transport permease protein
FLQ13_12510	COG1695	Transcriptional regulator
FLQ13_12515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FLQ13_12525	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FLQ13_12530	COG2318	DinB family
FLQ13_12540	COG1846	Transcriptional regulator
FLQ13_12545	COG0392	lysyltransferase activity
FLQ13_12545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FLQ13_12550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLQ13_12555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLQ13_12565	COG0384	phenazine biosynthesis protein PhzF
FLQ13_12570	COG0778	Nitroreductase
FLQ13_12585	COG1090	epimerase
FLQ13_12590	COG2137	regulation of response to DNA damage stimulus
FLQ13_12600	COG2814	Major facilitator Superfamily
FLQ13_12620	COG1476	TRANSCRIPTIONal
FLQ13_12625	COG3103	Sh3 type 3 domain protein
FLQ13_12630	COG5658	integral membrane protein
FLQ13_12635	COG0596	Alpha beta hydrolase
FLQ13_12640	COG0463	Glycosyl transferase, family 2
FLQ13_12645	COG4485	Bacterial membrane protein, YfhO
FLQ13_12650	COG1988	membrane-bound metal-dependent
FLQ13_12665	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_12680	COG3557	Belongs to the UPF0374 family
FLQ13_12685	COG1132	(ABC) transporter
FLQ13_12690	COG4129	membrane
FLQ13_12695	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLQ13_12700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FLQ13_12705	COG0735	belongs to the Fur family
FLQ13_12815	COG4326	sporulation control protein
FLQ13_12825	COG1063	alcohol dehydrogenase
FLQ13_12830	COG5577	PFAM Coat F domain
FLQ13_12840	COG3340	Belongs to the peptidase S51 family
FLQ13_12845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FLQ13_12855	COG0753	catalase activity
FLQ13_12865	COG1116	anion transmembrane transporter activity
FLQ13_12870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLQ13_12875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLQ13_12880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLQ13_12890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLQ13_12900	COG1476	TRANSCRIPTIONal
FLQ13_12910	COG3382	B3 4 domain protein
FLQ13_12915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FLQ13_12925	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FLQ13_12930	COG0789	Transcriptional regulator
FLQ13_12935	COG1664	Polymer-forming cytoskeletal
FLQ13_12940	COG1664	Polymer-forming cytoskeletal
FLQ13_12945	COG2766	serine protein kinase
FLQ13_12950	COG2718	Belongs to the UPF0229 family
FLQ13_12955	COG1846	Transcriptional regulator
FLQ13_12960	COG1566	PFAM secretion protein HlyD family protein
FLQ13_12965	COG2814	Major facilitator Superfamily
FLQ13_12970	COG0655	NAD(P)H dehydrogenase (quinone) activity
FLQ13_12985	COG1725	Transcriptional regulator
FLQ13_12990	COG1131	(ABC) transporter
FLQ13_12995	COG1131	(ABC) transporter
FLQ13_13000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FLQ13_13005	COG1278	Cold shock
FLQ13_13015	COG1464	Belongs to the NlpA lipoprotein family
FLQ13_13045	COG5577	PFAM Coat F domain
FLQ13_13060	COG0564	pseudouridine synthase activity
FLQ13_13070	COG0517	IMP dehydrogenase activity
FLQ13_13075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLQ13_13080	COG3153	acetyltransferase
FLQ13_13080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLQ13_13090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLQ13_13095	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FLQ13_13100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FLQ13_13105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLQ13_13110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FLQ13_13115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLQ13_13120	COG2203	Gaf domain
FLQ13_13120	COG4585	Histidine kinase
FLQ13_13125	COG2197	response regulator
FLQ13_13130	COG0431	NADPH-dependent FMN reductase
FLQ13_13145	COG1388	LysM domain
FLQ13_13145	COG0791	NLP P60 protein
FLQ13_13150	COG1959	2 iron, 2 sulfur cluster binding
FLQ13_13155	COG0668	transmembrane transport
FLQ13_13160	COG2719	SpoVR family
FLQ13_13170	COG0791	NLP P60 protein
FLQ13_13170	COG1388	LysM domain
FLQ13_13175	COG0583	DNA-binding transcription factor activity
FLQ13_13180	COG0372	Belongs to the citrate synthase family
FLQ13_13185	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_13190	COG0531	amino acid
FLQ13_13195	COG0733	neurotransmitter:sodium symporter activity
FLQ13_13200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLQ13_13205	COG0456	acetyltransferase
FLQ13_13220	COG1595	DNA-templated transcription, initiation
FLQ13_13225	COG0667	Aldo Keto reductase
FLQ13_13230	COG0204	Acyl-transferase
FLQ13_13235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLQ13_13240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLQ13_13245	COG1253	flavin adenine dinucleotide binding
FLQ13_13250	COG0789	Transcriptional regulator
FLQ13_13255	COG0436	Aminotransferase
FLQ13_13260	COG1253	flavin adenine dinucleotide binding
FLQ13_13265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLQ13_13270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLQ13_13275	COG0584	glycerophosphoryl diester phosphodiesterase
FLQ13_13285	COG0668	transmembrane transport
FLQ13_13290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FLQ13_13295	COG0726	polysaccharide deacetylase
FLQ13_13300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLQ13_13305	COG1757	Na H antiporter
FLQ13_13310	COG0589	response to stress
FLQ13_13320	COG1132	(ABC) transporter
FLQ13_13325	COG1132	(ABC) transporter
FLQ13_13330	COG0702	epimerase
FLQ13_13350	COG0189	ligase activity
FLQ13_13355	COG0189	ligase activity
FLQ13_13360	COG4399	Belongs to the UPF0754 family
FLQ13_13365	COG3679	Belongs to the UPF0342 family
FLQ13_13370	COG4335	DNA alkylation repair
FLQ13_13375	COG0561	phosphatase activity
FLQ13_13380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLQ13_13385	COG0475	glutathione-regulated potassium exporter activity
FLQ13_13390	COG0490	domain, Protein
FLQ13_13400	COG1024	Enoyl-CoA hydratase
FLQ13_13410	COG4152	abc transporter atp-binding protein
FLQ13_13415	COG1668	transmembrane transport
FLQ13_13420	COG0420	3'-5' exonuclease activity
FLQ13_13425	COG4717	serine-type aminopeptidase activity
FLQ13_13430	COG3481	metal-dependent phosphohydrolase, HD sub domain
FLQ13_13470	COG1846	Transcriptional regulator
FLQ13_13475	COG4980	gas vesicle protein
FLQ13_13490	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FLQ13_13495	COG0537	adenosine 5'-monophosphoramidase activity
FLQ13_13500	COG1131	(ABC) transporter
FLQ13_13505	COG4473	ABC transporter
FLQ13_13515	COG1473	amidohydrolase
FLQ13_13520	COG3069	C4-dicarboxylate transmembrane transporter activity
FLQ13_13530	COG2329	Antibiotic biosynthesis monooxygenase
FLQ13_13535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLQ13_13540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FLQ13_13555	COG1309	transcriptional regulator
FLQ13_13560	COG1511	domain protein
FLQ13_13565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLQ13_13570	COG4377	Putative membrane peptidase family (DUF2324)
FLQ13_13580	COG1363	Peptidase, m42
FLQ13_13585	COG4405	Protein conserved in bacteria
FLQ13_13590	COG1301	dicarboxylic acid transport
FLQ13_13600	COG1234	tRNA 3'-trailer cleavage
FLQ13_13605	COG0095	Lipoate-protein ligase
FLQ13_13610	COG0702	epimerase
FLQ13_13615	COG0318	PFAM AMP-dependent synthetase and ligase
FLQ13_13625	COG0501	Belongs to the peptidase M48B family
FLQ13_13630	COG1404	Belongs to the peptidase S8 family
FLQ13_13640	COG0604	alcohol dehydrogenase
FLQ13_13645	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FLQ13_13650	COG0406	alpha-ribazole phosphatase activity
FLQ13_13655	COG0183	Belongs to the thiolase family
FLQ13_13670	COG0840	transmembrane signaling receptor activity
FLQ13_13675	COG0723	plastoquinol--plastocyanin reductase activity
FLQ13_13675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLQ13_13680	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_13695	COG4974	Belongs to the 'phage' integrase family
FLQ13_13710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLQ13_13725	COG0210	DNA helicase
FLQ13_13760	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_13770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLQ13_13785	COG0398	Pfam SNARE associated Golgi protein
FLQ13_13790	COG0681	Belongs to the peptidase S26 family
FLQ13_13800	COG1846	Transcriptional regulator
FLQ13_13810	COG0738	Major facilitator superfamily
FLQ13_13820	COG0561	phosphatase activity
FLQ13_13825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLQ13_13830	COG1609	Transcriptional regulator
FLQ13_13840	COG2814	Major facilitator Superfamily
FLQ13_13840	COG0477	Major facilitator Superfamily
FLQ13_13845	COG4533	DNA binding
FLQ13_13855	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FLQ13_13860	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FLQ13_13865	COG1074	ATP-dependent DNA helicase activity
FLQ13_13870	COG0420	3'-5' exonuclease activity
FLQ13_13875	COG0419	ATPase involved in DNA repair
FLQ13_13880	COG1403	HNH endonuclease
FLQ13_13920	COG5337	Spore coat protein CotH
FLQ13_13925	COG0179	Fumarylacetoacetate (FAA) hydrolase
FLQ13_13935	COG1404	Belongs to the peptidase S8 family
FLQ13_13945	COG0367	asparagine synthase
FLQ13_13950	COG2318	DinB family
FLQ13_13955	COG1562	ergosterol biosynthetic process
FLQ13_13965	COG1917	Cupin 2, conserved barrel domain protein
FLQ13_13965	COG2207	Transcriptional regulator
FLQ13_13970	COG1609	Transcriptional regulator
FLQ13_13975	COG0673	inositol 2-dehydrogenase activity
FLQ13_13980	COG2318	DinB family
FLQ13_13990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLQ13_13995	COG1357	PFAM Pentapeptide repeats (8 copies)
FLQ13_14000	COG2267	carboxylic ester hydrolase activity
FLQ13_14005	COG0529	Catalyzes the synthesis of activated sulfate
FLQ13_14010	COG2046	Belongs to the sulfate adenylyltransferase family
FLQ13_14015	COG0175	sulfate reduction
FLQ13_14020	COG2045	Belongs to the ComB family
FLQ13_14025	COG1809	phosphosulfolactate synthase activity
FLQ13_14035	COG4948	Mandelate Racemase Muconate Lactonizing
FLQ13_14040	COG2814	Major facilitator Superfamily
FLQ13_14045	COG0454	-acetyltransferase
FLQ13_14050	COG2153	protein acetylation
FLQ13_14055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FLQ13_14055	COG0646	methionine synthase
FLQ13_14060	COG1666	GTP binding
FLQ13_14065	COG2996	Protein conserved in bacteria
FLQ13_14085	COG1695	Transcriptional regulator
FLQ13_14100	COG3227	Zinc metalloprotease (Elastase)
FLQ13_14105	COG1307	EDD domain protein, DegV family
FLQ13_14110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLQ13_14125	COG0561	phosphatase activity
FLQ13_14130	COG1073	alpha beta
FLQ13_14135	COG2151	metal-sulfur cluster biosynthetic enzyme
FLQ13_14145	COG0277	FAD linked oxidase domain protein
FLQ13_14150	COG2271	Major facilitator Superfamily
FLQ13_14170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLQ13_14175	COG0505	Belongs to the CarA family
FLQ13_14180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FLQ13_14185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FLQ13_14210	COG1744	ABC transporter substrate-binding protein PnrA-like
FLQ13_14225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLQ13_14230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLQ13_14235	COG5504	Zn-dependent protease
FLQ13_14240	COG0444	Belongs to the ABC transporter superfamily
FLQ13_14245	COG4608	Belongs to the ABC transporter superfamily
FLQ13_14260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLQ13_14270	COG0180	Tryptophanyl-tRNA synthetase
FLQ13_14280	COG4166	transmembrane transport
FLQ13_14285	COG0601	transmembrane transport
FLQ13_14290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLQ13_14295	COG0444	Belongs to the ABC transporter superfamily
FLQ13_14300	COG4608	Belongs to the ABC transporter superfamily
FLQ13_14305	COG2814	Major facilitator Superfamily
FLQ13_14310	COG0456	acetyltransferase
FLQ13_14315	COG1393	Belongs to the ArsC family
FLQ13_14320	COG0861	Integral membrane protein TerC family
FLQ13_14330	COG4862	establishment of competence for transformation
FLQ13_14335	COG4469	Competence protein
FLQ13_14340	COG1164	Oligoendopeptidase f
FLQ13_14360	COG2346	COG2346, Truncated hemoglobins
FLQ13_14365	COG0741	lytic transglycosylase activity
FLQ13_14370	COG4116	CYTH
FLQ13_14380	COG2357	RelA SpoT domain protein
FLQ13_14385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLQ13_14390	COG0564	pseudouridine synthase activity
FLQ13_14395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FLQ13_14405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FLQ13_14410	COG0352	thiamine-phosphate diphosphorylase activity
FLQ13_14415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLQ13_14420	COG2104	thiamine diphosphate biosynthetic process
FLQ13_14425	COG2022	thiamine diphosphate biosynthetic process
FLQ13_14430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLQ13_14435	COG0351	phosphomethylpyrimidine kinase
FLQ13_14440	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FLQ13_14495	COG0210	DNA helicase
FLQ13_14505	COG2153	protein acetylation
FLQ13_14510	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FLQ13_14515	COG2382	esterase
FLQ13_14520	COG0626	cystathionine gamma-synthase activity
FLQ13_14530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLQ13_14595	COG0457	Tetratricopeptide repeat
FLQ13_14605	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FLQ13_14660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLQ13_14665	COG0583	DNA-binding transcription factor activity
FLQ13_14700	COG0109	protoheme IX farnesyltransferase activity
FLQ13_14710	COG0726	polysaccharide deacetylase
FLQ13_14725	COG5504	Zn-dependent protease
FLQ13_14730	COG2205	protein histidine kinase activity
FLQ13_14740	COG3383	formate dehydrogenase (NAD+) activity
FLQ13_14745	COG2427	Protein of unknown function (DUF1641)
FLQ13_14765	COG2124	cytochrome p450
FLQ13_14770	COG1819	glycosyl
FLQ13_14785	COG1587	Uroporphyrinogen-III synthase
FLQ13_14790	COG0390	transport system, permease component
FLQ13_14795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLQ13_14800	COG0697	spore germination
FLQ13_14805	COG4297	protein containing double-stranded beta helix domain
FLQ13_14815	COG1252	NADH dehydrogenase
FLQ13_14820	COG1904	glucuronate isomerase
FLQ13_14830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FLQ13_14835	COG1063	alcohol dehydrogenase
FLQ13_14840	COG1312	Catalyzes the dehydration of D-mannonate
FLQ13_14845	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_14850	COG2271	Major facilitator Superfamily
FLQ13_14855	COG1609	Transcriptional regulator
FLQ13_14860	COG0246	Mannitol dehydrogenase
FLQ13_14865	COG2721	sulfolactate sulfo-lyase activity
FLQ13_14870	COG0730	response to heat
FLQ13_14875	COG2318	DinB family
FLQ13_14880	COG0457	Tetratricopeptide repeat
FLQ13_14890	COG2350	Protein conserved in bacteria
FLQ13_14895	COG1388	LysM domain
FLQ13_14895	COG3409	Peptidoglycan-binding domain 1 protein
FLQ13_14895	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLQ13_14905	COG4195	phage-related replication protein
FLQ13_14915	COG2856	Zn peptidase
FLQ13_14920	COG1396	sequence-specific DNA binding
FLQ13_14930	COG1522	sequence-specific DNA binding
FLQ13_14935	COG1484	DNA-dependent DNA replication
FLQ13_14955	COG1595	DNA-templated transcription, initiation
FLQ13_14960	COG3728	DNA packaging
FLQ13_14960	COG5484	DNA packaging
FLQ13_14965	COG1783	phage Terminase large subunit
FLQ13_14970	COG5518	Phage portal protein
FLQ13_14975	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FLQ13_14980	COG4653	Phage capsid family
FLQ13_15040	COG4193	domain, Protein
FLQ13_15050	COG3628	GPW Gp25 family protein
FLQ13_15055	COG3299	homolog of phage Mu protein gp47
FLQ13_15060	COG3778	Protein conserved in bacteria
FLQ13_15100	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLQ13_15100	COG3409	Peptidoglycan-binding domain 1 protein
FLQ13_15105	COG3594	Acyltransferase
FLQ13_15125	COG0306	phosphate transporter
FLQ13_15130	COG1392	Phosphate transport regulator
FLQ13_15135	COG0531	amino acid
FLQ13_15140	COG0346	lactoylglutathione lyase activity
FLQ13_15145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FLQ13_15150	COG0463	Glycosyl transferase, family 2
FLQ13_15160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLQ13_15165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLQ13_15170	COG2362	D-Aminopeptidase
FLQ13_15175	COG0601	transmembrane transport
FLQ13_15185	COG0444	Belongs to the ABC transporter superfamily
FLQ13_15190	COG4166	transmembrane transport
FLQ13_15195	COG1619	proteins homologs of microcin C7 resistance protein MccF
FLQ13_15200	COG4948	Mandelate Racemase Muconate Lactonizing
FLQ13_15205	COG0791	NLP P60 protein
FLQ13_15210	COG4608	Belongs to the ABC transporter superfamily
FLQ13_15215	COG2706	6-phosphogluconolactonase activity
FLQ13_15220	COG1834	amidinotransferase
FLQ13_15225	COG1607	acyl-coa hydrolase
FLQ13_15230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLQ13_15230	COG1017	nitric oxide dioxygenase activity
FLQ13_15240	COG2323	membrane
FLQ13_15245	COG2318	DinB family
FLQ13_15250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLQ13_15255	COG2076	Multidrug Resistance protein
FLQ13_15260	COG2076	Multidrug Resistance protein
FLQ13_15265	COG0788	formyltetrahydrofolate deformylase activity
FLQ13_15275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FLQ13_15280	COG1764	response to oxidative stress
FLQ13_15285	COG1846	Transcriptional regulator
FLQ13_15290	COG1764	response to oxidative stress
FLQ13_15295	COG0457	Tetratricopeptide repeat
FLQ13_15295	COG0463	Glycosyl transferase, family 2
FLQ13_15300	COG0590	tRNA wobble adenosine to inosine editing
FLQ13_15305	COG0406	alpha-ribazole phosphatase activity
FLQ13_15310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FLQ13_15320	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_15325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLQ13_15335	COG4721	ABC-type cobalt transport system, permease component
FLQ13_15345	COG0745	RESPONSE REGULATOR receiver
FLQ13_15355	COG3212	peptidase
FLQ13_15360	COG3212	peptidase
FLQ13_15375	COG2239	Acts as a magnesium transporter
FLQ13_15380	COG0789	Transcriptional regulator
FLQ13_15395	COG1846	Transcriptional regulator
FLQ13_15405	COG0726	polysaccharide deacetylase
FLQ13_15410	COG1408	metallophosphoesterase
FLQ13_15425	COG3285	dna ligase
FLQ13_15425	COG1793	dna ligase
FLQ13_15430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FLQ13_15435	COG5001	Diguanylate cyclase
FLQ13_15435	COG3300	MHYT domain
FLQ13_15440	COG0586	Pfam SNARE associated Golgi protein
FLQ13_15445	COG0861	Integral membrane protein TerC family
FLQ13_15450	COG1191	sigma factor activity
FLQ13_15470	COG0501	Belongs to the peptidase M48B family
FLQ13_15475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLQ13_15490	COG3594	Acyltransferase
FLQ13_15495	COG5002	protein histidine kinase activity
FLQ13_15500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLQ13_15510	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FLQ13_15515	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FLQ13_15520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLQ13_15525	COG0436	Aminotransferase
FLQ13_15530	COG1850	ribulose-bisphosphate carboxylase activity
FLQ13_15535	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FLQ13_15540	COG0235	Class ii aldolase
FLQ13_15545	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FLQ13_15550	COG3339	Conserved Protein
FLQ13_15565	COG3852	Histidine kinase
FLQ13_15575	COG1846	Transcriptional regulator
FLQ13_15580	COG1360	Flagellar Motor Protein
FLQ13_15585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FLQ13_15590	COG0542	response to heat
FLQ13_15595	COG3949	Membrane
FLQ13_15600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FLQ13_15605	COG0720	synthase
FLQ13_15610	COG0602	queuosine metabolic process
FLQ13_15615	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FLQ13_15620	COG1388	LysM domain
FLQ13_15620	COG4641	Protein conserved in bacteria
FLQ13_15630	COG3858	chitin binding
FLQ13_15640	COG4873	Protein conserved in bacteria
FLQ13_15650	COG3773	Cell wall hydrolase
FLQ13_15655	COG2244	polysaccharide biosynthetic process
FLQ13_15660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_15665	COG2217	Heavy metal translocating P-type atpase
FLQ13_15680	COG1609	Transcriptional regulator
FLQ13_15685	COG3711	transcriptional antiterminator
FLQ13_15690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLQ13_15690	COG2190	(PTS) system
FLQ13_15690	COG1263	PTS System
FLQ13_15695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLQ13_15700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLQ13_15710	COG1533	DNA photolyase activity
FLQ13_15715	COG0456	acetyltransferase
FLQ13_15720	COG0840	transmembrane signaling receptor activity
FLQ13_15725	COG2084	Dehydrogenase
FLQ13_15730	COG2340	Cysteine-rich secretory protein family
FLQ13_15740	COG4191	Histidine kinase
FLQ13_15745	COG0436	Aminotransferase
FLQ13_15755	COG0784	Response regulator, receiver
FLQ13_15755	COG0835	chemotaxis
FLQ13_15765	COG2814	Major facilitator Superfamily
FLQ13_15770	COG1376	ErfK ybiS ycfS ynhG family protein
FLQ13_15780	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_15785	COG3409	Peptidoglycan-binding domain 1 protein
FLQ13_15795	COG2200	EAL domain
FLQ13_15800	COG3546	catalase activity
FLQ13_15805	COG4703	Protein of unknown function (DUF1797)
FLQ13_15810	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FLQ13_15820	COG0517	IMP dehydrogenase activity
FLQ13_15825	COG0583	DNA-binding transcription factor activity
FLQ13_15830	COG0716	FMN binding
FLQ13_15840	COG0716	FMN binding
FLQ13_15845	COG2171	N-acyltransferase activity
FLQ13_15850	COG1473	amidohydrolase
FLQ13_15860	COG0668	transmembrane transport
FLQ13_15865	COG0450	alkyl hydroperoxide reductase
FLQ13_15870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_15885	COG0746	molybdenum cofactor guanylyltransferase activity
FLQ13_15895	COG0303	'Molybdopterin
FLQ13_15900	COG1763	Mo-molybdopterin cofactor biosynthetic process
FLQ13_15905	COG0314	molybdopterin synthase activity
FLQ13_15910	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FLQ13_15915	COG1132	(ABC) transporter
FLQ13_15920	COG1132	(ABC) transporter
FLQ13_15930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLQ13_15935	COG1136	(ABC) transporter
FLQ13_15940	COG0577	efflux transmembrane transporter activity
FLQ13_15950	COG1105	Belongs to the carbohydrate kinase PfkB family
FLQ13_15960	COG0681	Belongs to the peptidase S26 family
FLQ13_15970	COG0488	(ABC) transporter
FLQ13_15975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLQ13_15980	COG2309	aminopeptidase activity
FLQ13_15990	COG1077	Cell shape determining protein MreB Mrl
FLQ13_15995	COG2002	toxin-antitoxin pair type II binding
FLQ13_16000	COG3852	Histidine kinase
FLQ13_16005	COG2105	PFAM AIG2 family protein
FLQ13_16005	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FLQ13_16010	COG0569	domain protein
FLQ13_16015	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FLQ13_16020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLQ13_16030	COG0561	phosphatase activity
FLQ13_16035	COG0242	peptide deformylase activity
FLQ13_16045	COG0497	DNA recombination
FLQ13_16050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLQ13_16055	COG0022	dehydrogenase e1 component
FLQ13_16060	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLQ13_16065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLQ13_16070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_16080	COG1982	Orn Lys Arg decarboxylase major
FLQ13_16085	COG4476	Belongs to the UPF0223 family
FLQ13_16090	COG4493	Belongs to the UPF0637 family
FLQ13_16110	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FLQ13_16160	COG4896	Protein conserved in bacteria
FLQ13_16170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FLQ13_16175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FLQ13_16180	COG2066	Belongs to the glutaminase family
FLQ13_16185	COG4838	Belongs to the UPF0358 family
FLQ13_16190	COG0772	Belongs to the SEDS family
FLQ13_16195	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FLQ13_16205	COG0109	protoheme IX farnesyltransferase activity
FLQ13_16220	COG1845	cytochrome c oxidase, subunit III
FLQ13_16225	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FLQ13_16230	COG3336	cytochrome c oxidase
FLQ13_16240	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FLQ13_16245	COG2340	Cysteine-rich secretory protein family
FLQ13_16260	COG3679	Belongs to the UPF0342 family
FLQ13_16265	COG4471	UPF0298 protein
FLQ13_16280	COG3314	Sporulation integral membrane protein YlbJ
FLQ13_16285	COG1752	Esterase of the alpha-beta hydrolase superfamily
FLQ13_16290	COG3480	Lon protease (S16) C-terminal proteolytic domain
FLQ13_16300	COG1323	Belongs to the UPF0348 family
FLQ13_16305	COG1399	metal-binding, possibly nucleic acid-binding protein
FLQ13_16310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FLQ13_16320	COG0454	-acetyltransferase
FLQ13_16325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLQ13_16330	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FLQ13_16335	COG2001	Belongs to the MraZ family
FLQ13_16340	COG0275	rRNA processing
FLQ13_16345	COG4839	cell division protein FtsL
FLQ13_16355	COG0768	penicillin binding
FLQ13_16360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLQ13_16365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLQ13_16370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLQ13_16375	COG0772	Belongs to the SEDS family
FLQ13_16380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLQ13_16385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FLQ13_16390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FLQ13_16395	COG3879	Bacterial protein of unknown function (DUF881)
FLQ13_16400	COG3879	Bacterial protein of unknown function (DUF881)
FLQ13_16405	COG3856	small basic protein
FLQ13_16415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FLQ13_16420	COG4412	M6 family metalloprotease domain protein
FLQ13_16420	COG1404	Belongs to the peptidase S8 family
FLQ13_16430	COG1191	sigma factor activity
FLQ13_16435	COG1191	sigma factor activity
FLQ13_16440	COG1119	ATPase activity
FLQ13_16450	COG1873	PFAM PRC-barrel domain
FLQ13_16460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FLQ13_16465	COG1799	cell septum assembly
FLQ13_16470	COG0762	integral membrane protein
FLQ13_16480	COG3599	regulation of cell shape
FLQ13_16485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FLQ13_16495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLQ13_16500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FLQ13_16505	COG0564	pseudouridine synthase activity
FLQ13_16515	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FLQ13_16520	COG2233	PERMEase
FLQ13_16525	COG0540	Belongs to the ATCase OTCase family
FLQ13_16530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FLQ13_16535	COG0505	Belongs to the CarA family
FLQ13_16540	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FLQ13_16545	COG0543	2 iron, 2 sulfur cluster binding
FLQ13_16550	COG0167	dihydroorotate dehydrogenase activity
FLQ13_16555	COG0284	orotidine-5'-phosphate decarboxylase activity
FLQ13_16560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FLQ13_16565	COG0175	sulfate reduction
FLQ13_16570	COG0306	phosphate transporter
FLQ13_16575	COG2046	Belongs to the sulfate adenylyltransferase family
FLQ13_16580	COG0529	Catalyzes the synthesis of activated sulfate
FLQ13_16585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FLQ13_16590	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
FLQ13_16595	COG1648	precorrin-2 dehydrogenase activity
FLQ13_16605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FLQ13_16610	COG1561	YicC-like family, N-terminal region
FLQ13_16615	COG2052	Domain of unknown function (DUF370)
FLQ13_16620	COG0194	GDP metabolic process
FLQ13_16625	COG1758	RNA polymerase activity
FLQ13_16630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLQ13_16635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLQ13_16640	COG0242	peptide deformylase activity
FLQ13_16645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FLQ13_16650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLQ13_16650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FLQ13_16655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FLQ13_16660	COG0631	protein serine/threonine phosphatase activity
FLQ13_16665	COG0515	serine threonine protein kinase
FLQ13_16665	COG2815	serine threonine protein kinase
FLQ13_16670	COG1162	GTPase activity
FLQ13_16675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLQ13_16680	COG1564	THIamine pyrophosphokinase
FLQ13_16690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FLQ13_16695	COG1302	Protein conserved in bacteria
FLQ13_16700	COG1461	Dihydroxyacetone kinase
FLQ13_16705	COG1760	l-serine dehydratase
FLQ13_16710	COG1760	l-serine dehydratase
FLQ13_16715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLQ13_16720	COG1349	DNA-binding transcription factor activity
FLQ13_16720	COG2050	protein possibly involved in aromatic compounds catabolism
FLQ13_16725	COG0416	fatty acid biosynthetic process
FLQ13_16730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLQ13_16735	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_16740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLQ13_16745	COG0571	ribonuclease III activity
FLQ13_16755	COG0552	protein localization to endoplasmic reticulum
FLQ13_16765	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FLQ13_16770	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FLQ13_16775	COG0228	four-way junction DNA binding
FLQ13_16780	COG1837	Belongs to the UPF0109 family
FLQ13_16790	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FLQ13_16795	COG0336	Belongs to the RNA methyltransferase TrmD family
FLQ13_16800	COG0335	large ribosomal subunit rRNA binding
FLQ13_16805	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FLQ13_16810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLQ13_16820	COG2257	FlhB HrpN YscU SpaS Family
FLQ13_16825	COG0045	succinate-CoA ligase (ADP-forming) activity
FLQ13_16830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FLQ13_16835	COG0758	DNA mediated transformation
FLQ13_16840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLQ13_16845	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FLQ13_16850	COG4974	Belongs to the 'phage' integrase family
FLQ13_16855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FLQ13_16860	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FLQ13_16865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FLQ13_16870	COG1815	bacterial-type flagellum-dependent cell motility
FLQ13_16875	COG1558	bacterial-type flagellum-dependent cell motility
FLQ13_16880	COG1677	Flagellar hook-basal body complex protein FliE
FLQ13_16885	COG1766	The M ring may be actively involved in energy transduction
FLQ13_16890	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLQ13_16895	COG1317	bacterial-type flagellum organization
FLQ13_16905	COG2882	bacterial-type flagellum organization
FLQ13_16910	COG3334	PFAM MgtE intracellular
FLQ13_16915	COG3144	bacterial-type flagellum assembly
FLQ13_16920	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FLQ13_16925	COG4786	Flagellar basal body rod
FLQ13_16930	COG1582	Flagellar protein (FlbD)
FLQ13_16935	COG1580	Controls the rotational direction of flagella during chemotaxis
FLQ13_16940	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLQ13_16945	COG1776	CheC inhibitor of MCP methylation
FLQ13_16945	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLQ13_16950	COG2201	protein-glutamate methylesterase activity
FLQ13_16955	COG3190	flagellar
FLQ13_16960	COG1338	Plays a role in the flagellum-specific transport system
FLQ13_16965	COG1987	bacterial-type flagellum assembly
FLQ13_16970	COG1684	flagellar biosynthetic protein fliR
FLQ13_16975	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLQ13_16980	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLQ13_16985	COG1419	protein localization to endoplasmic reticulum
FLQ13_16990	COG0455	bacterial-type flagellum organization
FLQ13_17000	COG0643	Histidine kinase
FLQ13_17000	COG2198	Histidine kinase
FLQ13_17005	COG0835	chemotaxis
FLQ13_17010	COG1776	CheC inhibitor of MCP methylation
FLQ13_17015	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FLQ13_17020	COG1191	sigma factor activity
FLQ13_17030	COG0052	Belongs to the universal ribosomal protein uS2 family
FLQ13_17035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FLQ13_17040	COG0528	UMP kinase activity
FLQ13_17045	COG0233	cytoplasmic translational termination
FLQ13_17050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLQ13_17055	COG4589	Belongs to the CDS family
FLQ13_17060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FLQ13_17065	COG0750	zinc metalloprotease
FLQ13_17070	COG0442	prolyl-tRNA aminoacylation
FLQ13_17075	COG2176	DNA-directed DNA polymerase activity
FLQ13_17080	COG0779	Required for maturation of 30S ribosomal subunits
FLQ13_17085	COG0195	Participates in both transcription termination and antitermination
FLQ13_17090	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FLQ13_17095	COG1358	cellular component organization or biogenesis
FLQ13_17100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FLQ13_17105	COG1550	Protein conserved in bacteria
FLQ13_17110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FLQ13_17115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FLQ13_17120	COG0196	riboflavin kinase activity
FLQ13_17130	COG1185	polyribonucleotide nucleotidyltransferase activity
FLQ13_17135	COG0726	polysaccharide deacetylase
FLQ13_17140	COG0612	Peptidase, M16
FLQ13_17145	COG1873	PFAM PRC-barrel domain
FLQ13_17155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLQ13_17160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLQ13_17170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLQ13_17175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLQ13_17180	COG0740	serine-type endopeptidase activity
FLQ13_17195	COG2188	Transcriptional regulator
FLQ13_17205	COG0612	Peptidase, M16
FLQ13_17210	COG0612	Peptidase, M16
FLQ13_17215	COG0300	oxidoreductase activity
FLQ13_17230	COG1426	Protein conserved in bacteria
FLQ13_17235	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLQ13_17240	COG1546	Belongs to the CinA family
FLQ13_17240	COG1058	Belongs to the CinA family
FLQ13_17245	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FLQ13_17255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FLQ13_17260	COG1418	mRNA catabolic process
FLQ13_17265	COG1692	metallophosphoesterase
FLQ13_17270	COG2359	stage V sporulation protein S
FLQ13_17275	COG1063	alcohol dehydrogenase
FLQ13_17280	COG0156	8-amino-7-oxononanoate synthase activity
FLQ13_17285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLQ13_17290	COG4550	Control of competence regulator ComK, YlbF/YmcA
FLQ13_17300	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FLQ13_17305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FLQ13_17375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLQ13_17380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLQ13_17390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLQ13_17390	COG2070	2-Nitropropane dioxygenase
FLQ13_17395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLQ13_17400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLQ13_17405	COG3425	synthase
FLQ13_17410	COG1024	Enoyl-CoA hydratase
FLQ13_17415	COG1024	Enoyl-CoA hydratase
FLQ13_17430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLQ13_17430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLQ13_17430	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_17430	COG3321	synthase
FLQ13_17430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLQ13_17440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLQ13_17440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FLQ13_17440	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FLQ13_17440	COG3321	synthase
FLQ13_17445	COG2124	cytochrome p450
FLQ13_17455	COG1404	Belongs to the peptidase S8 family
FLQ13_17465	COG4195	phage-related replication protein
FLQ13_17470	COG1764	response to oxidative stress
FLQ13_17495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FLQ13_17500	COG1923	regulation of RNA biosynthetic process
FLQ13_17520	COG1780	Probably involved in ribonucleotide reductase function
FLQ13_17525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLQ13_17530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLQ13_17535	COG4112	unkown
FLQ13_17540	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLQ13_17550	COG0464	growth
FLQ13_17555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLQ13_17560	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FLQ13_17565	COG0789	Transcriptional regulator
FLQ13_17570	COG0174	glutamine synthetase
FLQ13_17590	COG0457	Tetratricopeptide repeat
FLQ13_17605	COG0456	acetyltransferase
FLQ13_17625	COG5444	nuclease activity
FLQ13_17640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLQ13_17665	COG2273	Hydrolase Family 16
FLQ13_17675	COG0457	Tetratricopeptide repeat
FLQ13_17705	COG0726	polysaccharide deacetylase
FLQ13_17730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLQ13_17735	COG2720	vancomycin resistance protein
FLQ13_17740	COG3739	integral membrane protein
FLQ13_17745	COG3655	Transcriptional regulator
FLQ13_17755	COG2135	peptidase activity
FLQ13_17770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLQ13_17780	COG3832	glyoxalase III activity
FLQ13_17815	COG4195	phage-related replication protein
FLQ13_17835	COG0346	lactoylglutathione lyase activity
FLQ13_17850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLQ13_17855	COG1388	LysM domain
FLQ13_17860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FLQ13_17865	COG4224	UPF0291 protein
FLQ13_17870	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FLQ13_17880	COG3763	UPF0154 protein
FLQ13_17890	COG0785	Cytochrome C biogenesis protein
FLQ13_17895	COG2201	protein-glutamate methylesterase activity
FLQ13_17900	COG4846	Membrane protein involved in cytochrome C biogenesis
FLQ13_17910	COG0071	Belongs to the small heat shock protein (HSP20) family
FLQ13_17925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FLQ13_17930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_17950	COG0824	Thioesterase
FLQ13_17960	COG4841	protein insertion into membrane
FLQ13_17965	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FLQ13_17970	COG1832	CoA-binding protein
FLQ13_17975	COG0187	DNA topoisomerase II activity
FLQ13_17980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLQ13_17990	COG1115	amino acid carrier protein
FLQ13_17995	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FLQ13_18010	COG5520	Belongs to the glycosyl hydrolase 30 family
FLQ13_18025	COG2246	polysaccharide biosynthetic process
FLQ13_18045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FLQ13_18050	COG1024	Enoyl-CoA hydratase
FLQ13_18055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLQ13_18060	COG0511	ligase activity, forming carbon-carbon bonds
FLQ13_18065	COG0439	Biotin carboxylase
FLQ13_18070	COG0318	PFAM AMP-dependent synthetase and ligase
FLQ13_18075	COG1960	acyl-CoA dehydrogenase activity
FLQ13_18090	COG1649	PFAM Uncharacterised BCR, COG1649
FLQ13_18110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLQ13_18115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLQ13_18125	COG2027	D-alanyl-D-alanine carboxypeptidase
FLQ13_18130	COG2017	converts alpha-aldose to the beta-anomer
FLQ13_18135	COG0534	Mate efflux family protein
FLQ13_18150	COG0582	viral genome integration into host DNA
FLQ13_18155	COG0166	Belongs to the GPI family
FLQ13_18160	COG0405	Gamma-glutamyltransferase
FLQ13_18165	COG0583	DNA-binding transcription factor activity
FLQ13_18170	COG0604	alcohol dehydrogenase
FLQ13_18175	COG0493	'glutamate synthase
FLQ13_18180	COG0069	glutamate synthase activity
FLQ13_18180	COG0070	glutamate synthase
FLQ13_18180	COG0067	glutamate synthase
FLQ13_18185	COG0583	DNA-binding transcription factor activity
FLQ13_18190	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLQ13_18210	COG0300	oxidoreductase activity
FLQ13_18215	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FLQ13_18240	COG1131	(ABC) transporter
FLQ13_18255	COG1070	Carbohydrate kinase
FLQ13_18260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLQ13_18280	COG0673	inositol 2-dehydrogenase activity
FLQ13_18285	COG1082	Xylose isomerase domain protein TIM barrel
FLQ13_18290	COG1609	Transcriptional regulator
FLQ13_18295	COG4305	rare lipoprotein A
FLQ13_18300	COG3619	membrane
FLQ13_18310	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_18350	COG1525	nuclease
FLQ13_18355	COG1231	oxidoreductase activity
FLQ13_18365	COG1070	Carbohydrate kinase
FLQ13_18380	COG3507	Belongs to the glycosyl hydrolase 43 family
FLQ13_18410	COG3397	chitin binding
FLQ13_18415	COG2318	DinB family
FLQ13_18425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLQ13_18520	COG0457	Tetratricopeptide repeat
FLQ13_18530	COG0574	Belongs to the PEP-utilizing enzyme family
FLQ13_18530	COG3848	Pyruvate phosphate dikinase
FLQ13_18550	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_18555	COG1733	regulation of RNA biosynthetic process
FLQ13_18565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLQ13_18570	COG0662	Cupin 2, conserved barrel domain protein
FLQ13_18570	COG2207	Transcriptional regulator
FLQ13_18575	COG0456	acetyltransferase
FLQ13_18580	COG1309	transcriptional regulator
FLQ13_18585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLQ13_18590	COG3708	Transcriptional regulator
FLQ13_18595	COG2378	regulation of single-species biofilm formation
FLQ13_18605	COG0640	Transcriptional regulator
FLQ13_18610	COG0741	lytic transglycosylase activity
FLQ13_18615	COG2322	membrane
FLQ13_18630	COG1619	proteins homologs of microcin C7 resistance protein MccF
FLQ13_18635	COG3239	Fatty acid desaturase
FLQ13_18640	COG4585	Histidine kinase
FLQ13_18645	COG2197	response regulator
FLQ13_18655	COG1388	LysM domain
FLQ13_18655	COG3584	3D domain protein
FLQ13_18660	COG0514	ATP-dependent DNA helicase (RecQ)
FLQ13_18670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FLQ13_18675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLQ13_18690	COG1012	belongs to the aldehyde dehydrogenase family
FLQ13_18695	COG1657	PFAM Prenyltransferase squalene oxidase
FLQ13_18700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLQ13_18705	COG0733	neurotransmitter:sodium symporter activity
FLQ13_18710	COG0385	Bile acid
FLQ13_18715	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLQ13_18725	COG4548	von Willebrand factor, type A
FLQ13_18730	COG0714	Associated with various cellular activities
FLQ13_18735	COG2032	superoxide dismutase activity
FLQ13_18745	COG1819	glycosyl
FLQ13_18750	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FLQ13_18755	COG0534	Mate efflux family protein
FLQ13_18760	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_18765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLQ13_18770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLQ13_18780	COG2962	Rard protein
FLQ13_18800	COG1942	4-Oxalocrotonate Tautomerase
FLQ13_18810	COG1733	regulation of RNA biosynthetic process
FLQ13_18815	COG0778	Nitroreductase
FLQ13_18825	COG0346	lactoylglutathione lyase activity
FLQ13_18835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLQ13_18840	COG3409	Peptidoglycan-binding domain 1 protein
FLQ13_18840	COG0793	Belongs to the peptidase S41A family
FLQ13_18845	COG2226	methyltransferase
FLQ13_18855	COG1876	peptidase activity
FLQ13_18860	COG0813	purine-nucleoside phosphorylase activity
FLQ13_18875	COG0671	phosphoesterase, PA-phosphatase related
FLQ13_18900	COG4479	Belongs to the UPF0346 family
FLQ13_18910	COG1509	lysine 2,3-aminomutase activity
FLQ13_18915	COG0456	acetyltransferase
FLQ13_18920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLQ13_18925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FLQ13_18930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FLQ13_18935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLQ13_18945	COG0456	acetyltransferase
FLQ13_18950	COG0463	Glycosyl transferase, family 2
FLQ13_18965	COG4641	Protein conserved in bacteria
FLQ13_18975	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
FLQ13_18980	COG1086	Polysaccharide biosynthesis protein
FLQ13_18990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLQ13_18995	COG1846	Transcriptional regulator
FLQ13_19010	COG4698	Protein conserved in bacteria
FLQ13_19015	COG2755	lipolytic protein G-D-S-L family
FLQ13_19020	COG1999	signal sequence binding
FLQ13_19040	COG1272	protein, Hemolysin III
FLQ13_19045	COG0204	Acyl-transferase
FLQ13_19050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLQ13_19060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FLQ13_19070	COG2521	methyltransferase
FLQ13_19070	COG2136	Putative SAM-dependent methyltransferase
FLQ13_19080	COG0129	dihydroxy-acid dehydratase activity
FLQ13_19085	COG1413	lyase activity
FLQ13_19090	COG1418	mRNA catabolic process
FLQ13_19095	COG0386	Belongs to the glutathione peroxidase family
FLQ13_19100	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FLQ13_19105	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLQ13_19110	COG1278	Cold shock
FLQ13_19130	COG0328	RNA-DNA hybrid ribonuclease activity
FLQ13_19135	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FLQ13_19140	COG0328	RNA-DNA hybrid ribonuclease activity
FLQ13_19150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLQ13_19175	COG1755	Isoprenylcysteine carboxyl methyltransferase
FLQ13_19180	COG3424	synthase
FLQ13_19185	COG2233	PERMEase
FLQ13_19190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLQ13_19195	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FLQ13_19210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLQ13_19215	COG1609	Transcriptional regulator
FLQ13_19220	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FLQ13_19225	COG1028	Short-chain dehydrogenase reductase Sdr
FLQ13_19230	COG1199	ATP-dependent helicase activity
FLQ13_19245	COG0116	Belongs to the methyltransferase superfamily
FLQ13_19260	COG4474	Belongs to the UPF0398 family
FLQ13_19275	COG3359	exonuclease
FLQ13_19285	COG2190	(PTS) system
FLQ13_19290	COG0071	Belongs to the small heat shock protein (HSP20) family
FLQ13_19325	COG3331	DNA recombination
FLQ13_19330	COG4499	WXG100 protein secretion system (Wss), protein YukC
FLQ13_19330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLQ13_19340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FLQ13_19345	COG3935	DnaD domain protein
FLQ13_19350	COG0017	Asparaginyl-tRNA synthetase
FLQ13_19355	COG0436	Aminotransferase
FLQ13_19360	COG5353	protein conserved in bacteria
FLQ13_19370	COG1199	ATP-dependent helicase activity
FLQ13_19370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FLQ13_19375	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FLQ13_19380	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FLQ13_19385	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FLQ13_19390	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FLQ13_19390	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FLQ13_19395	COG0617	tRNA 3'-terminal CCA addition
FLQ13_19400	COG0438	transferase activity, transferring glycosyl groups
FLQ13_19405	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLQ13_19410	COG1803	Methylglyoxal synthase
FLQ13_19415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FLQ13_19420	COG1694	Mazg nucleotide pyrophosphohydrolase
FLQ13_19425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLQ13_19435	COG4347	Protein of unknown function (DUF1405)
FLQ13_19440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLQ13_19440	COG2010	Cytochrome c
FLQ13_19445	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLQ13_19465	COG0457	Tetratricopeptide repeat
FLQ13_19470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FLQ13_19475	COG0287	Prephenate dehydrogenase
FLQ13_19480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLQ13_19485	COG0159	tryptophan synthase activity
FLQ13_19490	COG0133	tryptophan synthase activity
FLQ13_19495	COG0135	phosphoribosylanthranilate isomerase activity
FLQ13_19505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FLQ13_19510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLQ13_19515	COG4401	Chorismate mutase type I
FLQ13_19520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FLQ13_19525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FLQ13_19530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FLQ13_19535	COG0105	UTP biosynthetic process
FLQ13_19545	COG2226	methyltransferase
FLQ13_19550	COG0142	geranyltranstransferase activity
FLQ13_19560	COG0302	gtp cyclohydrolase
FLQ13_19565	COG0776	regulation of translation
FLQ13_19570	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FLQ13_19585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FLQ13_19590	COG1160	GTP binding
FLQ13_19615	COG1304	FMN binding
FLQ13_19620	COG0539	negative regulation of cytoplasmic translation
FLQ13_19625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FLQ13_19635	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FLQ13_19640	COG2959	enzyme of heme biosynthesis
FLQ13_19645	COG3409	Peptidoglycan-binding domain 1 protein
FLQ13_19645	COG3773	Cell wall hydrolase
FLQ13_19650	COG2339	peptidase activity
FLQ13_19655	COG0492	ferredoxin-NADP+ reductase activity
FLQ13_19665	COG4862	establishment of competence for transformation
FLQ13_19670	COG1408	metallophosphoesterase
FLQ13_19680	COG1388	LysM domain
FLQ13_19685	COG1266	CAAX protease self-immunity
FLQ13_19695	COG4955	Helix-turn-helix domain
FLQ13_19700	COG1141	Ferredoxin
FLQ13_19705	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FLQ13_19710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLQ13_19715	COG0710	3-dehydroquinate dehydratase activity
FLQ13_19725	COG1595	DNA-templated transcription, initiation
FLQ13_19730	COG5002	protein histidine kinase activity
FLQ13_19735	COG0745	RESPONSE REGULATOR receiver
FLQ13_19740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLQ13_19750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLQ13_19755	COG1187	pseudouridine synthase activity
FLQ13_19760	COG0700	Nucleoside recognition
FLQ13_19765	COG2715	membrane protein required for spore maturation
FLQ13_19770	COG1686	Belongs to the peptidase S11 family
FLQ13_19780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FLQ13_19785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FLQ13_19795	COG1547	Domain of unknown function (DUF309)
FLQ13_19800	COG0456	acetyltransferase
FLQ13_19805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FLQ13_19810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLQ13_19810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLQ13_19815	COG0307	riboflavin synthase, alpha
FLQ13_19820	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLQ13_19820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLQ13_19830	COG0681	Belongs to the peptidase S26 family
FLQ13_19835	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
FLQ13_19840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLQ13_19845	COG4086	secreted protein
FLQ13_19850	COG0019	diaminopimelate decarboxylase activity
FLQ13_19855	COG0697	spore germination
FLQ13_19870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLQ13_19890	COG1191	sigma factor activity
FLQ13_19895	COG2172	sigma factor antagonist activity
FLQ13_19900	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_19905	COG1686	Belongs to the peptidase S11 family
FLQ13_19910	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FLQ13_19915	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FLQ13_19920	COG4974	Belongs to the 'phage' integrase family
FLQ13_19935	COG1300	Membrane
FLQ13_19945	COG0281	malic enzyme
FLQ13_19955	COG1027	Aspartate ammonia-lyase
FLQ13_19960	COG0252	asparaginase activity
FLQ13_19965	COG1396	sequence-specific DNA binding
FLQ13_19970	COG1379	DNA repair
FLQ13_19975	COG0494	nUDIX hydrolase
FLQ13_19985	COG0667	Aldo Keto reductase
FLQ13_19995	COG1073	alpha beta
FLQ13_20005	COG4918	Iron-sulphur cluster biosynthesis
FLQ13_20010	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FLQ13_20010	COG0456	acetyltransferase
FLQ13_20015	COG2329	Antibiotic biosynthesis monooxygenase
FLQ13_20020	COG0456	acetyltransferase
FLQ13_20030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLQ13_20040	COG2211	Major facilitator Superfamily
FLQ13_20045	COG0346	lactoylglutathione lyase activity
FLQ13_20050	COG1072	(Pantothenic acid kinase))
FLQ13_20055	COG3048	D-serine ammonia-lyase activity
FLQ13_20060	COG0300	oxidoreductase activity
FLQ13_20065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLQ13_20070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLQ13_20080	COG1902	pentaerythritol trinitrate reductase activity
FLQ13_20085	COG0596	Alpha beta hydrolase
FLQ13_20095	COG1234	tRNA 3'-trailer cleavage
FLQ13_20100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FLQ13_20110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLQ13_20115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLQ13_20125	COG0706	membrane insertase activity
FLQ13_20130	COG3361	conserved protein (COG2071)
FLQ13_20135	COG2195	Cleaves the N-terminal amino acid of tripeptides
FLQ13_20140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FLQ13_20145	COG0346	lactoylglutathione lyase activity
FLQ13_20150	COG1376	ErfK ybiS ycfS ynhG family protein
FLQ13_20155	COG4129	membrane
FLQ13_20160	COG1126	abc transporter atp-binding protein
FLQ13_20165	COG0765	amino acid transport
FLQ13_20170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLQ13_20180	COG1597	lipid kinase activity
FLQ13_20185	COG2814	Major facilitator Superfamily
FLQ13_20190	COG0789	Transcriptional regulator
FLQ13_20190	COG4978	Transcriptional regulator
FLQ13_20195	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLQ13_20200	COG0022	dehydrogenase e1 component
FLQ13_20205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLQ13_20210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLQ13_20215	COG3426	butyrate kinase activity
FLQ13_20220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLQ13_20240	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FLQ13_20250	COG0372	Belongs to the citrate synthase family
FLQ13_20255	COG1960	acyl-CoA dehydrogenase activity
FLQ13_20260	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLQ13_20265	COG0183	Belongs to the thiolase family
FLQ13_20270	COG0584	glycerophosphoryl diester phosphodiesterase
FLQ13_20275	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLQ13_20290	COG1902	pentaerythritol trinitrate reductase activity
FLQ13_20300	COG0745	RESPONSE REGULATOR receiver
FLQ13_20305	COG0750	zinc metalloprotease
FLQ13_20310	COG0497	DNA recombination
FLQ13_20315	COG1438	arginine binding
FLQ13_20320	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FLQ13_20325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FLQ13_20335	COG1722	exodeoxyribonuclease VII activity
FLQ13_20345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FLQ13_20350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLQ13_20355	COG1302	Protein conserved in bacteria
FLQ13_20360	COG0439	Biotin carboxylase
FLQ13_20365	COG0511	ligase activity, forming carbon-carbon bonds
FLQ13_20405	COG3854	ATPases associated with a variety of cellular activities
FLQ13_20415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FLQ13_20420	COG0006	proline dipeptidase activity
FLQ13_20425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FLQ13_20435	COG3872	metal-dependent enzyme
FLQ13_20445	COG1752	Esterase of the alpha-beta hydrolase superfamily
FLQ13_20450	COG1321	iron dependent repressor
FLQ13_20455	COG0095	Lipoate-protein ligase
FLQ13_20460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLQ13_20465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLQ13_20470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLQ13_20475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FLQ13_20480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLQ13_20495	COG1396	sequence-specific DNA binding
FLQ13_20505	COG0681	Belongs to the peptidase S26 family
FLQ13_20530	COG4940	Competence protein ComGF
FLQ13_20540	COG4970	Tfp pilus assembly protein FimT
FLQ13_20545	COG4537	Required for transformation and DNA binding
FLQ13_20550	COG1459	type II secretion system
FLQ13_20555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLQ13_20560	COG0517	IMP dehydrogenase activity
FLQ13_20565	COG0598	Magnesium transport protein CorA
FLQ13_20570	COG1253	flavin adenine dinucleotide binding
FLQ13_20575	COG1366	Belongs to the anti-sigma-factor antagonist family
FLQ13_20585	COG1393	Belongs to the ArsC family
FLQ13_20605	COG0011	TIGRFAM Protein of
FLQ13_20625	COG1940	carbohydrate kinase activity
FLQ13_20630	COG4483	Protein conserved in bacteria
FLQ13_20635	COG0457	Tetratricopeptide repeat
FLQ13_20635	COG0705	Rhomboid family
FLQ13_20645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLQ13_20650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FLQ13_20670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLQ13_20680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLQ13_20685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLQ13_20690	COG0581	inorganic phosphate transmembrane transporter activity
FLQ13_20695	COG0573	inorganic phosphate transmembrane transporter activity
FLQ13_20700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FLQ13_20710	COG0477	Major facilitator Superfamily
FLQ13_20715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLQ13_20720	COG2839	Protein conserved in bacteria
FLQ13_20725	COG5521	maltodextrose utilization protein MalA
FLQ13_20730	COG1388	LysM domain
FLQ13_20735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FLQ13_20740	COG4709	membrane
FLQ13_20745	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FLQ13_20750	COG0735	belongs to the Fur family
FLQ13_20755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLQ13_20765	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FLQ13_20770	COG0513	Belongs to the DEAD box helicase family
FLQ13_20780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FLQ13_20785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FLQ13_20790	COG2384	SAM-dependent methyltransferase
FLQ13_20795	COG2010	Cytochrome c
FLQ13_20800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLQ13_20805	COG0358	DNA primase activity
FLQ13_20810	COG1671	Belongs to the UPF0178 family
FLQ13_20815	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FLQ13_20820	COG0517	IMP dehydrogenase activity
FLQ13_20825	COG0751	glycine-tRNA ligase activity
FLQ13_20830	COG0752	glycyl-tRNA synthetase alpha subunit
FLQ13_20835	COG1381	Involved in DNA repair and RecF pathway recombination
FLQ13_20845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FLQ13_20850	COG0295	cytidine deaminase activity
FLQ13_20855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FLQ13_20860	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FLQ13_20865	COG1480	7TM receptor with intracellular HD hydrolase
FLQ13_20870	COG1702	phosphate starvation-inducible protein PhoH
FLQ13_20875	COG0561	phosphatase activity
FLQ13_20895	COG1030	water channel activity
FLQ13_20900	COG1610	YqeY-like protein
FLQ13_20905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FLQ13_20910	COG1283	sodium-dependent phosphate transmembrane transporter activity
FLQ13_20915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLQ13_20920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FLQ13_20925	COG2264	protein methyltransferase activity
FLQ13_20930	COG0484	heat shock protein binding
FLQ13_20940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FLQ13_20945	COG1420	regulation of RNA biosynthetic process
FLQ13_20950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLQ13_20955	COG0481	GTPase activity
FLQ13_20965	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLQ13_20970	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FLQ13_20975	COG0268	Binds directly to 16S ribosomal RNA
FLQ13_20980	COG1466	dna polymerase III delta subunit
FLQ13_20995	COG2333	competence protein COMEC
FLQ13_20995	COG0658	competence protein
FLQ13_21000	COG2131	deaminase
FLQ13_21005	COG1555	photosystem II stabilization
FLQ13_21005	COG1596	polysaccharide export
FLQ13_21010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLQ13_21015	COG2226	methyltransferase
FLQ13_21020	COG0799	negative regulation of ribosome biogenesis
FLQ13_21025	COG1713	HD superfamily hydrolase involved in NAD metabolism
FLQ13_21030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FLQ13_21035	COG1534	Rna-binding protein
FLQ13_21040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLQ13_21045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FLQ13_21050	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FLQ13_21060	COG2755	lipolytic protein G-D-S-L family
FLQ13_21065	COG3409	Peptidoglycan-binding domain 1 protein
FLQ13_21065	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLQ13_21070	COG0398	Pfam SNARE associated Golgi protein
FLQ13_21085	COG3209	COG3209 Rhs family protein
FLQ13_21120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLQ13_21135	COG2814	Major facilitator Superfamily
FLQ13_21140	COG0457	Tetratricopeptide repeat
FLQ13_21145	COG2072	flavoprotein involved in K transport
FLQ13_21150	COG1230	cation diffusion facilitator family transporter
FLQ13_21180	COG0730	response to heat
FLQ13_21185	COG0425	Belongs to the sulfur carrier protein TusA family
FLQ13_21190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLQ13_21190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLQ13_21200	COG0425	Belongs to the sulfur carrier protein TusA family
FLQ13_21200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLQ13_21215	COG1937	Protein conserved in bacteria
FLQ13_21230	COG0662	Cupin 2, conserved barrel domain protein
FLQ13_21260	COG1335	isochorismatase
FLQ13_21285	COG3677	Transposase