locus-tag	class	description
C2H92_00005	COG0778	Nitroreductase
C2H92_00020	COG1090	epimerase
C2H92_00025	COG2137	regulation of response to DNA damage stimulus
C2H92_00035	COG2814	Major facilitator Superfamily
C2H92_00055	COG1476	TRANSCRIPTIONal
C2H92_00060	COG3103	Sh3 type 3 domain protein
C2H92_00065	COG5658	integral membrane protein
C2H92_00070	COG0596	Alpha beta hydrolase
C2H92_00075	COG0463	Glycosyl transferase, family 2
C2H92_00080	COG4485	Bacterial membrane protein, YfhO
C2H92_00085	COG1988	membrane-bound metal-dependent
C2H92_00090	COG1194	a g-specific adenine glycosylase
C2H92_00100	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_00115	COG3557	Belongs to the UPF0374 family
C2H92_00120	COG1132	(ABC) transporter
C2H92_00125	COG4129	membrane
C2H92_00130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C2H92_00135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2H92_00140	COG0735	belongs to the Fur family
C2H92_00270	COG4326	sporulation control protein
C2H92_00280	COG1063	alcohol dehydrogenase
C2H92_00285	COG5577	PFAM Coat F domain
C2H92_00295	COG3340	Belongs to the peptidase S51 family
C2H92_00300	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C2H92_00315	COG0753	catalase activity
C2H92_00320	COG1116	anion transmembrane transporter activity
C2H92_00325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2H92_00330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2H92_00335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2H92_00345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C2H92_00355	COG1476	TRANSCRIPTIONal
C2H92_00365	COG3382	B3 4 domain protein
C2H92_00370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C2H92_00380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C2H92_00390	COG0789	Transcriptional regulator
C2H92_00395	COG1664	Polymer-forming cytoskeletal
C2H92_00400	COG1664	Polymer-forming cytoskeletal
C2H92_00405	COG2766	serine protein kinase
C2H92_00410	COG2718	Belongs to the UPF0229 family
C2H92_00415	COG1846	Transcriptional regulator
C2H92_00420	COG1566	PFAM secretion protein HlyD family protein
C2H92_00425	COG2814	Major facilitator Superfamily
C2H92_00430	COG0655	NAD(P)H dehydrogenase (quinone) activity
C2H92_00445	COG1725	Transcriptional regulator
C2H92_00450	COG1131	(ABC) transporter
C2H92_00455	COG1131	(ABC) transporter
C2H92_00460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C2H92_00465	COG1278	Cold shock
C2H92_00475	COG1464	Belongs to the NlpA lipoprotein family
C2H92_00480	COG3706	GGDEF domain
C2H92_00485	COG1823	symporter activity
C2H92_00530	COG5577	PFAM Coat F domain
C2H92_00535	COG0737	Belongs to the 5'-nucleotidase family
C2H92_00535	COG1525	nuclease
C2H92_00535	COG4085	toxin activity
C2H92_00540	COG3764	Sortase (surface protein transpeptidase)
C2H92_00545	COG0564	pseudouridine synthase activity
C2H92_00555	COG0517	IMP dehydrogenase activity
C2H92_00560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2H92_00565	COG3153	acetyltransferase
C2H92_00565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2H92_00580	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C2H92_00585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C2H92_00590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C2H92_00600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C2H92_00605	COG4585	Histidine kinase
C2H92_00605	COG2203	Gaf domain
C2H92_00610	COG2197	response regulator
C2H92_00615	COG0431	NADPH-dependent FMN reductase
C2H92_00630	COG1388	LysM domain
C2H92_00630	COG0791	NLP P60 protein
C2H92_00635	COG1959	2 iron, 2 sulfur cluster binding
C2H92_00640	COG0668	transmembrane transport
C2H92_00645	COG2719	SpoVR family
C2H92_00650	COG1785	Belongs to the alkaline phosphatase family
C2H92_00655	COG0791	NLP P60 protein
C2H92_00655	COG1388	LysM domain
C2H92_00660	COG0583	DNA-binding transcription factor activity
C2H92_00670	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_00675	COG0531	amino acid
C2H92_00680	COG0733	neurotransmitter:sodium symporter activity
C2H92_00685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2H92_00690	COG0456	acetyltransferase
C2H92_00705	COG1595	DNA-templated transcription, initiation
C2H92_00715	COG0204	Acyl-transferase
C2H92_00720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2H92_00725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2H92_00730	COG1253	flavin adenine dinucleotide binding
C2H92_00735	COG0789	Transcriptional regulator
C2H92_00740	COG0436	Aminotransferase
C2H92_00745	COG1253	flavin adenine dinucleotide binding
C2H92_00750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C2H92_00755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C2H92_00760	COG0584	glycerophosphoryl diester phosphodiesterase
C2H92_00770	COG0668	transmembrane transport
C2H92_00775	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C2H92_00780	COG0726	polysaccharide deacetylase
C2H92_00785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2H92_00790	COG1757	Na H antiporter
C2H92_00795	COG0589	response to stress
C2H92_00805	COG1132	(ABC) transporter
C2H92_00810	COG1132	(ABC) transporter
C2H92_00815	COG0702	epimerase
C2H92_00835	COG0189	ligase activity
C2H92_00840	COG0189	ligase activity
C2H92_00845	COG4399	Belongs to the UPF0754 family
C2H92_00850	COG3679	Belongs to the UPF0342 family
C2H92_00855	COG4335	DNA alkylation repair
C2H92_00860	COG0561	phosphatase activity
C2H92_00865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2H92_00870	COG0475	glutathione-regulated potassium exporter activity
C2H92_00875	COG0490	domain, Protein
C2H92_00885	COG1024	Enoyl-CoA hydratase
C2H92_00895	COG4152	abc transporter atp-binding protein
C2H92_00900	COG1668	transmembrane transport
C2H92_00905	COG0420	3'-5' exonuclease activity
C2H92_00910	COG4717	serine-type aminopeptidase activity
C2H92_00915	COG3481	metal-dependent phosphohydrolase, HD sub domain
C2H92_00925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2H92_00955	COG1846	Transcriptional regulator
C2H92_00960	COG4980	gas vesicle protein
C2H92_00975	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C2H92_00980	COG0537	adenosine 5'-monophosphoramidase activity
C2H92_00985	COG1131	(ABC) transporter
C2H92_00990	COG4473	ABC transporter
C2H92_01000	COG1473	amidohydrolase
C2H92_01005	COG3069	C4-dicarboxylate transmembrane transporter activity
C2H92_01015	COG2329	Antibiotic biosynthesis monooxygenase
C2H92_01025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C2H92_01030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C2H92_01040	COG1309	transcriptional regulator
C2H92_01045	COG1511	domain protein
C2H92_01050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C2H92_01055	COG4377	Putative membrane peptidase family (DUF2324)
C2H92_01065	COG1363	Peptidase, m42
C2H92_01070	COG4405	Protein conserved in bacteria
C2H92_01075	COG1301	dicarboxylic acid transport
C2H92_01085	COG1234	tRNA 3'-trailer cleavage
C2H92_01090	COG0095	Lipoate-protein ligase
C2H92_01095	COG0702	epimerase
C2H92_01100	COG0318	PFAM AMP-dependent synthetase and ligase
C2H92_01110	COG0501	Belongs to the peptidase M48B family
C2H92_01115	COG1404	Belongs to the peptidase S8 family
C2H92_01120	COG0456	acetyltransferase
C2H92_01125	COG0604	alcohol dehydrogenase
C2H92_01130	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C2H92_01135	COG0406	alpha-ribazole phosphatase activity
C2H92_01140	COG0183	Belongs to the thiolase family
C2H92_01145	COG0318	PFAM AMP-dependent synthetase and ligase
C2H92_01150	COG1268	BioY protein
C2H92_01160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2H92_01160	COG0723	plastoquinol--plastocyanin reductase activity
C2H92_01165	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_01175	COG4903	ComK protein
C2H92_01180	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_01190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2H92_01205	COG0398	Pfam SNARE associated Golgi protein
C2H92_01210	COG0681	Belongs to the peptidase S26 family
C2H92_01215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2H92_01220	COG1846	Transcriptional regulator
C2H92_01230	COG0738	Major facilitator superfamily
C2H92_01235	COG0673	inositol 2-dehydrogenase activity
C2H92_01240	COG0561	phosphatase activity
C2H92_01245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C2H92_01250	COG1609	Transcriptional regulator
C2H92_01260	COG3180	Ammonia monooxygenase
C2H92_01265	COG2814	Major facilitator Superfamily
C2H92_01265	COG0477	Major facilitator Superfamily
C2H92_01270	COG4533	DNA binding
C2H92_01280	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C2H92_01285	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C2H92_01290	COG1074	ATP-dependent DNA helicase activity
C2H92_01295	COG0420	3'-5' exonuclease activity
C2H92_01300	COG0419	ATPase involved in DNA repair
C2H92_01305	COG1403	HNH endonuclease
C2H92_01345	COG5337	Spore coat protein CotH
C2H92_01350	COG0179	Fumarylacetoacetate (FAA) hydrolase
C2H92_01360	COG1404	Belongs to the peptidase S8 family
C2H92_01370	COG0367	asparagine synthase
C2H92_01375	COG2318	DinB family
C2H92_01380	COG1562	ergosterol biosynthetic process
C2H92_01385	COG0534	Mate efflux family protein
C2H92_01390	COG1917	Cupin 2, conserved barrel domain protein
C2H92_01390	COG2207	Transcriptional regulator
C2H92_01400	COG0673	inositol 2-dehydrogenase activity
C2H92_01405	COG2318	DinB family
C2H92_01410	COG1279	arginine transmembrane transporter activity
C2H92_01415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2H92_01420	COG1357	PFAM Pentapeptide repeats (8 copies)
C2H92_01425	COG2267	carboxylic ester hydrolase activity
C2H92_01430	COG0529	Catalyzes the synthesis of activated sulfate
C2H92_01435	COG2046	Belongs to the sulfate adenylyltransferase family
C2H92_01440	COG0175	sulfate reduction
C2H92_01445	COG2045	Belongs to the ComB family
C2H92_01450	COG1809	phosphosulfolactate synthase activity
C2H92_01455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2H92_01460	COG4948	Mandelate Racemase Muconate Lactonizing
C2H92_01465	COG2814	Major facilitator Superfamily
C2H92_01470	COG0454	-acetyltransferase
C2H92_01475	COG2153	protein acetylation
C2H92_01485	COG1666	GTP binding
C2H92_01490	COG2996	Protein conserved in bacteria
C2H92_01510	COG1695	Transcriptional regulator
C2H92_01525	COG3227	Zinc metalloprotease (Elastase)
C2H92_01530	COG1307	EDD domain protein, DegV family
C2H92_01535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2H92_01550	COG0561	phosphatase activity
C2H92_01555	COG1073	alpha beta
C2H92_01560	COG2151	metal-sulfur cluster biosynthetic enzyme
C2H92_01570	COG0277	FAD linked oxidase domain protein
C2H92_01575	COG2271	Major facilitator Superfamily
C2H92_01580	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C2H92_01595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C2H92_01600	COG0505	Belongs to the CarA family
C2H92_01610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C2H92_01625	COG2267	carboxylic ester hydrolase activity
C2H92_01635	COG1744	ABC transporter substrate-binding protein PnrA-like
C2H92_01650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C2H92_01655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2H92_01660	COG5504	Zn-dependent protease
C2H92_01665	COG0444	Belongs to the ABC transporter superfamily
C2H92_01670	COG4608	Belongs to the ABC transporter superfamily
C2H92_01680	COG0601	transmembrane transport
C2H92_01685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2H92_01695	COG0180	Tryptophanyl-tRNA synthetase
C2H92_01705	COG4166	transmembrane transport
C2H92_01710	COG0601	transmembrane transport
C2H92_01715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2H92_01720	COG0444	Belongs to the ABC transporter superfamily
C2H92_01725	COG4608	Belongs to the ABC transporter superfamily
C2H92_01730	COG2814	Major facilitator Superfamily
C2H92_01735	COG0456	acetyltransferase
C2H92_01740	COG1393	Belongs to the ArsC family
C2H92_01745	COG0861	Integral membrane protein TerC family
C2H92_01750	COG4862	establishment of competence for transformation
C2H92_01755	COG4469	Competence protein
C2H92_01760	COG1164	Oligoendopeptidase f
C2H92_01775	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C2H92_01780	COG2346	COG2346, Truncated hemoglobins
C2H92_01785	COG0741	lytic transglycosylase activity
C2H92_01790	COG4116	CYTH
C2H92_01800	COG2357	RelA SpoT domain protein
C2H92_01805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C2H92_01810	COG0564	pseudouridine synthase activity
C2H92_01815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C2H92_01820	COG0569	domain protein
C2H92_01820	COG0475	glutathione-regulated potassium exporter activity
C2H92_01825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C2H92_01830	COG0352	thiamine-phosphate diphosphorylase activity
C2H92_01835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2H92_01840	COG2104	thiamine diphosphate biosynthetic process
C2H92_01845	COG2022	thiamine diphosphate biosynthetic process
C2H92_01850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2H92_01855	COG0351	phosphomethylpyrimidine kinase
C2H92_01860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C2H92_01920	COG0210	DNA helicase
C2H92_01930	COG2153	protein acetylation
C2H92_01935	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C2H92_01940	COG2382	esterase
C2H92_01945	COG0626	cystathionine gamma-synthase activity
C2H92_01950	COG0626	cystathionine gamma-synthase activity
C2H92_01955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_01960	COG5505	Protein of unknown function (DUF819)
C2H92_01985	COG0457	Tetratricopeptide repeat
C2H92_02085	COG5444	nuclease activity
C2H92_02110	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C2H92_02140	COG3409	Peptidoglycan-binding domain 1 protein
C2H92_02160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_02200	COG0726	polysaccharide deacetylase
C2H92_02215	COG5504	Zn-dependent protease
C2H92_02220	COG2205	protein histidine kinase activity
C2H92_02230	COG3383	formate dehydrogenase (NAD+) activity
C2H92_02235	COG2427	Protein of unknown function (DUF1641)
C2H92_02245	COG1051	belongs to the nudix hydrolase family
C2H92_02255	COG2124	cytochrome p450
C2H92_02275	COG1587	Uroporphyrinogen-III synthase
C2H92_02280	COG0390	transport system, permease component
C2H92_02285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C2H92_02290	COG0697	spore germination
C2H92_02310	COG1904	glucuronate isomerase
C2H92_02315	COG2211	Major facilitator Superfamily
C2H92_02320	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C2H92_02325	COG1063	alcohol dehydrogenase
C2H92_02330	COG1312	Catalyzes the dehydration of D-mannonate
C2H92_02335	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_02340	COG2271	Major facilitator Superfamily
C2H92_02345	COG1609	Transcriptional regulator
C2H92_02350	COG0246	Mannitol dehydrogenase
C2H92_02355	COG2721	sulfolactate sulfo-lyase activity
C2H92_02360	COG0730	response to heat
C2H92_02365	COG2318	DinB family
C2H92_02370	COG0457	Tetratricopeptide repeat
C2H92_02380	COG2350	Protein conserved in bacteria
C2H92_02385	COG1388	LysM domain
C2H92_02385	COG3409	Peptidoglycan-binding domain 1 protein
C2H92_02385	COG5632	N-Acetylmuramoyl-L-alanine amidase
C2H92_02395	COG4195	phage-related replication protein
C2H92_02400	COG3546	catalase activity
C2H92_02405	COG2856	Zn peptidase
C2H92_02410	COG1396	sequence-specific DNA binding
C2H92_02420	COG1522	sequence-specific DNA binding
C2H92_02425	COG1484	DNA-dependent DNA replication
C2H92_02445	COG1595	DNA-templated transcription, initiation
C2H92_02450	COG3728	DNA packaging
C2H92_02450	COG5484	DNA packaging
C2H92_02455	COG1783	phage Terminase large subunit
C2H92_02460	COG5518	Phage portal protein
C2H92_02465	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C2H92_02470	COG4653	Phage capsid family
C2H92_02520	COG5412	phage tail tape measure protein
C2H92_02520	COG3953	SLT domain
C2H92_02520	COG5412	phage tail tape measure protein
C2H92_02520	COG3953	SLT domain
C2H92_02520	COG3953	SLT domain
C2H92_02520	COG5412	phage tail tape measure protein
C2H92_02525	COG1652	LysM domain
C2H92_02530	COG4193	domain, Protein
C2H92_02540	COG3628	GPW Gp25 family protein
C2H92_02545	COG3299	homolog of phage Mu protein gp47
C2H92_02550	COG3778	Protein conserved in bacteria
C2H92_02585	COG5632	N-Acetylmuramoyl-L-alanine amidase
C2H92_02585	COG3409	Peptidoglycan-binding domain 1 protein
C2H92_02600	COG0306	phosphate transporter
C2H92_02605	COG1392	Phosphate transport regulator
C2H92_02610	COG0531	amino acid
C2H92_02615	COG0346	lactoylglutathione lyase activity
C2H92_02620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C2H92_02625	COG0463	Glycosyl transferase, family 2
C2H92_02635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2H92_02645	COG2362	D-Aminopeptidase
C2H92_02650	COG0601	transmembrane transport
C2H92_02655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2H92_02660	COG0444	Belongs to the ABC transporter superfamily
C2H92_02665	COG4166	transmembrane transport
C2H92_02670	COG1619	proteins homologs of microcin C7 resistance protein MccF
C2H92_02675	COG4948	Mandelate Racemase Muconate Lactonizing
C2H92_02680	COG0791	NLP P60 protein
C2H92_02685	COG4608	Belongs to the ABC transporter superfamily
C2H92_02690	COG2706	6-phosphogluconolactonase activity
C2H92_02695	COG1834	amidinotransferase
C2H92_02700	COG1607	acyl-coa hydrolase
C2H92_02705	COG1017	nitric oxide dioxygenase activity
C2H92_02705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2H92_02715	COG2323	membrane
C2H92_02720	COG2318	DinB family
C2H92_02725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_02730	COG2076	Multidrug Resistance protein
C2H92_02735	COG2076	Multidrug Resistance protein
C2H92_02740	COG0788	formyltetrahydrofolate deformylase activity
C2H92_02745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C2H92_02750	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C2H92_02755	COG1764	response to oxidative stress
C2H92_02760	COG1846	Transcriptional regulator
C2H92_02765	COG1764	response to oxidative stress
C2H92_02775	COG0590	tRNA wobble adenosine to inosine editing
C2H92_02780	COG0406	alpha-ribazole phosphatase activity
C2H92_02785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C2H92_02790	COG1404	Belongs to the peptidase S8 family
C2H92_02795	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_02800	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C2H92_02810	COG4721	ABC-type cobalt transport system, permease component
C2H92_02820	COG0745	RESPONSE REGULATOR receiver
C2H92_02825	COG3850	Histidine kinase
C2H92_02825	COG5002	protein histidine kinase activity
C2H92_02830	COG3212	peptidase
C2H92_02835	COG3212	peptidase
C2H92_02850	COG2239	Acts as a magnesium transporter
C2H92_02855	COG0789	Transcriptional regulator
C2H92_02870	COG1846	Transcriptional regulator
C2H92_02885	COG1408	metallophosphoesterase
C2H92_02895	COG0463	Glycosyl transferase, family 2
C2H92_02900	COG3285	dna ligase
C2H92_02900	COG1793	dna ligase
C2H92_02905	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C2H92_02910	COG5001	Diguanylate cyclase
C2H92_02910	COG3300	MHYT domain
C2H92_02915	COG0586	Pfam SNARE associated Golgi protein
C2H92_02920	COG0861	Integral membrane protein TerC family
C2H92_02925	COG1191	sigma factor activity
C2H92_02945	COG0501	Belongs to the peptidase M48B family
C2H92_02950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C2H92_02965	COG3594	Acyltransferase
C2H92_02970	COG5002	protein histidine kinase activity
C2H92_02975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C2H92_02980	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C2H92_02985	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C2H92_02990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2H92_02995	COG0436	Aminotransferase
C2H92_03000	COG1850	ribulose-bisphosphate carboxylase activity
C2H92_03005	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C2H92_03010	COG0235	Class ii aldolase
C2H92_03015	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C2H92_03025	COG3339	Conserved Protein
C2H92_03040	COG3852	Histidine kinase
C2H92_03050	COG1846	Transcriptional regulator
C2H92_03055	COG1360	Flagellar Motor Protein
C2H92_03060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C2H92_03065	COG0542	response to heat
C2H92_03070	COG3949	Membrane
C2H92_03075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C2H92_03080	COG0720	synthase
C2H92_03085	COG0602	queuosine metabolic process
C2H92_03090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C2H92_03145	COG4873	Protein conserved in bacteria
C2H92_03160	COG2244	polysaccharide biosynthetic process
C2H92_03165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_03170	COG2217	Heavy metal translocating P-type atpase
C2H92_03180	COG0006	proline dipeptidase activity
C2H92_03185	COG1609	Transcriptional regulator
C2H92_03190	COG3711	transcriptional antiterminator
C2H92_03195	COG1263	PTS System
C2H92_03195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H92_03195	COG2190	(PTS) system
C2H92_03200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H92_03205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2H92_03215	COG1533	DNA photolyase activity
C2H92_03220	COG0456	acetyltransferase
C2H92_03225	COG0840	transmembrane signaling receptor activity
C2H92_03235	COG2340	Cysteine-rich secretory protein family
C2H92_03245	COG4191	Histidine kinase
C2H92_03250	COG0436	Aminotransferase
C2H92_03260	COG0835	chemotaxis
C2H92_03260	COG0784	Response regulator, receiver
C2H92_03270	COG2814	Major facilitator Superfamily
C2H92_03275	COG1376	ErfK ybiS ycfS ynhG family protein
C2H92_03280	COG1408	metallophosphoesterase
C2H92_03285	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_03290	COG2200	EAL domain
C2H92_03295	COG3546	catalase activity
C2H92_03300	COG4703	Protein of unknown function (DUF1797)
C2H92_03305	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C2H92_03315	COG0517	IMP dehydrogenase activity
C2H92_03320	COG0583	DNA-binding transcription factor activity
C2H92_03325	COG0716	FMN binding
C2H92_03335	COG0716	FMN binding
C2H92_03340	COG2171	N-acyltransferase activity
C2H92_03345	COG1473	amidohydrolase
C2H92_03355	COG0668	transmembrane transport
C2H92_03360	COG0450	alkyl hydroperoxide reductase
C2H92_03365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_03385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2H92_03390	COG0303	'Molybdopterin
C2H92_03395	COG1763	Mo-molybdopterin cofactor biosynthetic process
C2H92_03405	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C2H92_03410	COG1132	(ABC) transporter
C2H92_03415	COG1132	(ABC) transporter
C2H92_03425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H92_03430	COG1136	(ABC) transporter
C2H92_03435	COG0577	efflux transmembrane transporter activity
C2H92_03440	COG1349	DNA-binding transcription factor activity
C2H92_03445	COG1105	Belongs to the carbohydrate kinase PfkB family
C2H92_03465	COG0488	(ABC) transporter
C2H92_03470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C2H92_03475	COG2309	aminopeptidase activity
C2H92_03485	COG1077	Cell shape determining protein MreB Mrl
C2H92_03495	COG2002	toxin-antitoxin pair type II binding
C2H92_03500	COG3852	Histidine kinase
C2H92_03510	COG0569	domain protein
C2H92_03515	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C2H92_03520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C2H92_03525	COG5503	Protein of unknown function (DUF1447)
C2H92_03530	COG0561	phosphatase activity
C2H92_03535	COG0242	peptide deformylase activity
C2H92_03545	COG0497	DNA recombination
C2H92_03550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C2H92_03555	COG0022	dehydrogenase e1 component
C2H92_03560	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2H92_03565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2H92_03570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_03580	COG1982	Orn Lys Arg decarboxylase major
C2H92_03585	COG4476	Belongs to the UPF0223 family
C2H92_03590	COG4493	Belongs to the UPF0637 family
C2H92_03600	COG0483	inositol monophosphate 1-phosphatase activity
C2H92_03610	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C2H92_03615	COG0657	acetylesterase activity
C2H92_03620	COG1959	2 iron, 2 sulfur cluster binding
C2H92_03640	COG1595	DNA-templated transcription, initiation
C2H92_03660	COG1217	gtp-binding protein TYPA
C2H92_03670	COG4896	Protein conserved in bacteria
C2H92_03680	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C2H92_03685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C2H92_03690	COG2066	Belongs to the glutaminase family
C2H92_03695	COG4838	Belongs to the UPF0358 family
C2H92_03700	COG0772	Belongs to the SEDS family
C2H92_03705	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C2H92_03710	COG1612	heme a metabolic process
C2H92_03715	COG0109	protoheme IX farnesyltransferase activity
C2H92_03720	COG2010	Cytochrome c
C2H92_03720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C2H92_03725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C2H92_03730	COG1845	cytochrome c oxidase, subunit III
C2H92_03735	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C2H92_03740	COG3336	cytochrome c oxidase
C2H92_03750	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C2H92_03755	COG2340	Cysteine-rich secretory protein family
C2H92_03770	COG3679	Belongs to the UPF0342 family
C2H92_03775	COG4471	UPF0298 protein
C2H92_03785	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C2H92_03795	COG1752	Esterase of the alpha-beta hydrolase superfamily
C2H92_03805	COG1323	Belongs to the UPF0348 family
C2H92_03825	COG0454	-acetyltransferase
C2H92_03835	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C2H92_03840	COG2001	Belongs to the MraZ family
C2H92_03845	COG0275	rRNA processing
C2H92_03850	COG4839	cell division protein FtsL
C2H92_03860	COG0768	penicillin binding
C2H92_03865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C2H92_03870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C2H92_03875	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C2H92_03880	COG0772	Belongs to the SEDS family
C2H92_03885	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C2H92_03890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C2H92_03895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C2H92_03905	COG3879	Bacterial protein of unknown function (DUF881)
C2H92_03910	COG3856	small basic protein
C2H92_03915	COG0849	cell division
C2H92_03920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C2H92_03935	COG1191	sigma factor activity
C2H92_03940	COG1191	sigma factor activity
C2H92_03945	COG1119	ATPase activity
C2H92_03950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2H92_03955	COG1873	PFAM PRC-barrel domain
C2H92_03960	COG1496	oxidoreductase activity
C2H92_03965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C2H92_03970	COG1799	cell septum assembly
C2H92_03975	COG0762	integral membrane protein
C2H92_03980	COG2302	S4 RNA-binding domain
C2H92_03985	COG3599	regulation of cell shape
C2H92_03990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C2H92_03995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2H92_04000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C2H92_04005	COG0564	pseudouridine synthase activity
C2H92_04015	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C2H92_04020	COG2233	PERMEase
C2H92_04025	COG0540	Belongs to the ATCase OTCase family
C2H92_04030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C2H92_04035	COG0505	Belongs to the CarA family
C2H92_04040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C2H92_04050	COG0167	dihydroorotate dehydrogenase activity
C2H92_04055	COG0284	orotidine-5'-phosphate decarboxylase activity
C2H92_04060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C2H92_04065	COG0175	sulfate reduction
C2H92_04070	COG0306	phosphate transporter
C2H92_04075	COG2046	Belongs to the sulfate adenylyltransferase family
C2H92_04080	COG0529	Catalyzes the synthesis of activated sulfate
C2H92_04085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C2H92_04090	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C2H92_04095	COG1648	precorrin-2 dehydrogenase activity
C2H92_04100	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C2H92_04105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C2H92_04110	COG1561	YicC-like family, N-terminal region
C2H92_04120	COG0194	GDP metabolic process
C2H92_04125	COG1758	RNA polymerase activity
C2H92_04130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C2H92_04135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C2H92_04140	COG0242	peptide deformylase activity
C2H92_04145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C2H92_04150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C2H92_04150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C2H92_04155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C2H92_04160	COG0631	protein serine/threonine phosphatase activity
C2H92_04165	COG0515	serine threonine protein kinase
C2H92_04165	COG2815	serine threonine protein kinase
C2H92_04170	COG1162	GTPase activity
C2H92_04175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2H92_04180	COG1564	THIamine pyrophosphokinase
C2H92_04190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C2H92_04195	COG1302	Protein conserved in bacteria
C2H92_04200	COG1461	Dihydroxyacetone kinase
C2H92_04205	COG1760	l-serine dehydratase
C2H92_04210	COG1760	l-serine dehydratase
C2H92_04215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C2H92_04220	COG2050	protein possibly involved in aromatic compounds catabolism
C2H92_04220	COG1349	DNA-binding transcription factor activity
C2H92_04225	COG0416	fatty acid biosynthetic process
C2H92_04230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C2H92_04235	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_04245	COG0571	ribonuclease III activity
C2H92_04250	COG1196	nuclear chromosome segregation
C2H92_04255	COG0552	protein localization to endoplasmic reticulum
C2H92_04265	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C2H92_04270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C2H92_04275	COG0228	four-way junction DNA binding
C2H92_04280	COG1837	Belongs to the UPF0109 family
C2H92_04290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C2H92_04295	COG0336	Belongs to the RNA methyltransferase TrmD family
C2H92_04300	COG0335	large ribosomal subunit rRNA binding
C2H92_04310	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C2H92_04320	COG2257	FlhB HrpN YscU SpaS Family
C2H92_04325	COG0045	succinate-CoA ligase (ADP-forming) activity
C2H92_04330	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2H92_04335	COG0758	DNA mediated transformation
C2H92_04340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C2H92_04345	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C2H92_04350	COG4974	Belongs to the 'phage' integrase family
C2H92_04355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C2H92_04360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C2H92_04365	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C2H92_04370	COG1815	bacterial-type flagellum-dependent cell motility
C2H92_04375	COG1558	bacterial-type flagellum-dependent cell motility
C2H92_04380	COG1677	Flagellar hook-basal body complex protein FliE
C2H92_04385	COG1766	The M ring may be actively involved in energy transduction
C2H92_04390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2H92_04395	COG1317	bacterial-type flagellum organization
C2H92_04400	COG1157	protein secretion by the type III secretion system
C2H92_04405	COG2882	bacterial-type flagellum organization
C2H92_04410	COG3334	PFAM MgtE intracellular
C2H92_04415	COG3144	bacterial-type flagellum assembly
C2H92_04420	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C2H92_04425	COG4786	Flagellar basal body rod
C2H92_04430	COG1582	Flagellar protein (FlbD)
C2H92_04435	COG1580	Controls the rotational direction of flagella during chemotaxis
C2H92_04440	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2H92_04445	COG1776	CheC inhibitor of MCP methylation
C2H92_04445	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2H92_04450	COG2201	protein-glutamate methylesterase activity
C2H92_04455	COG3190	flagellar
C2H92_04460	COG1338	Plays a role in the flagellum-specific transport system
C2H92_04465	COG1987	bacterial-type flagellum assembly
C2H92_04470	COG1684	flagellar biosynthetic protein fliR
C2H92_04475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C2H92_04480	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C2H92_04485	COG1419	protein localization to endoplasmic reticulum
C2H92_04490	COG0455	bacterial-type flagellum organization
C2H92_04495	COG2201	protein-glutamate methylesterase activity
C2H92_04500	COG2198	Histidine kinase
C2H92_04500	COG0643	Histidine kinase
C2H92_04505	COG0835	chemotaxis
C2H92_04510	COG1776	CheC inhibitor of MCP methylation
C2H92_04515	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C2H92_04520	COG1191	sigma factor activity
C2H92_04530	COG0052	Belongs to the universal ribosomal protein uS2 family
C2H92_04535	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C2H92_04540	COG0528	UMP kinase activity
C2H92_04545	COG0233	cytoplasmic translational termination
C2H92_04550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C2H92_04555	COG4589	Belongs to the CDS family
C2H92_04560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C2H92_04565	COG0750	zinc metalloprotease
C2H92_04570	COG0442	prolyl-tRNA aminoacylation
C2H92_04575	COG2176	DNA-directed DNA polymerase activity
C2H92_04580	COG0779	Required for maturation of 30S ribosomal subunits
C2H92_04585	COG0195	Participates in both transcription termination and antitermination
C2H92_04590	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C2H92_04595	COG1358	cellular component organization or biogenesis
C2H92_04600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C2H92_04605	COG1550	Protein conserved in bacteria
C2H92_04610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C2H92_04620	COG0196	riboflavin kinase activity
C2H92_04630	COG1185	polyribonucleotide nucleotidyltransferase activity
C2H92_04635	COG0726	polysaccharide deacetylase
C2H92_04645	COG1873	PFAM PRC-barrel domain
C2H92_04650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2H92_04655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C2H92_04665	COG0527	aspartate kinase activity
C2H92_04670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2H92_04675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C2H92_04680	COG0740	serine-type endopeptidase activity
C2H92_04695	COG2188	Transcriptional regulator
C2H92_04700	COG2814	Major facilitator Superfamily
C2H92_04705	COG0612	Peptidase, M16
C2H92_04710	COG0612	Peptidase, M16
C2H92_04715	COG0300	oxidoreductase activity
C2H92_04730	COG1426	Protein conserved in bacteria
C2H92_04735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C2H92_04740	COG1058	Belongs to the CinA family
C2H92_04740	COG1546	Belongs to the CinA family
C2H92_04745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C2H92_04750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2H92_04755	COG1418	mRNA catabolic process
C2H92_04760	COG1692	metallophosphoesterase
C2H92_04765	COG2359	stage V sporulation protein S
C2H92_04770	COG1063	alcohol dehydrogenase
C2H92_04775	COG0156	8-amino-7-oxononanoate synthase activity
C2H92_04780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C2H92_04785	COG4550	Control of competence regulator ComK, YlbF/YmcA
C2H92_04795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C2H92_04800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C2H92_04840	COG0582	viral genome integration into host DNA
C2H92_04885	COG5444	nuclease activity
C2H92_04935	COG3226	Transcriptional regulator
C2H92_04940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2H92_04945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C2H92_04950	COG3321	synthase
C2H92_04955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C2H92_04955	COG2070	2-Nitropropane dioxygenase
C2H92_04960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C2H92_04965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2H92_04970	COG3425	synthase
C2H92_04975	COG1024	Enoyl-CoA hydratase
C2H92_04980	COG1024	Enoyl-CoA hydratase
C2H92_04995	COG3321	synthase
C2H92_04995	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_04995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2H92_04995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2H92_04995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C2H92_05010	COG2124	cytochrome p450
C2H92_05020	COG1404	Belongs to the peptidase S8 family
C2H92_05030	COG4195	phage-related replication protein
C2H92_05035	COG1764	response to oxidative stress
C2H92_05065	COG1923	regulation of RNA biosynthetic process
C2H92_05090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2H92_05095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2H92_05100	COG4112	unkown
C2H92_05105	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H92_05110	COG1131	(ABC) transporter
C2H92_05120	COG0464	growth
C2H92_05125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C2H92_05130	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C2H92_05135	COG0789	Transcriptional regulator
C2H92_05140	COG0174	glutamine synthetase
C2H92_05160	COG0577	efflux transmembrane transporter activity
C2H92_05160	COG1136	(ABC) transporter
C2H92_05220	COG1621	beta-fructofuranosidase activity
C2H92_05230	COG0395	ABC-type sugar transport system, permease component
C2H92_05235	COG1175	transmembrane transport
C2H92_05245	COG1609	Transcriptional regulator
C2H92_05255	COG2273	Hydrolase Family 16
C2H92_05270	COG0457	Tetratricopeptide repeat
C2H92_05320	COG0726	polysaccharide deacetylase
C2H92_05345	COG1131	(ABC) transporter
C2H92_05370	COG2720	vancomycin resistance protein
C2H92_05375	COG3739	integral membrane protein
C2H92_05380	COG3655	Transcriptional regulator
C2H92_05390	COG2135	peptidase activity
C2H92_05395	COG5434	Belongs to the glycosyl hydrolase 28 family
C2H92_05415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C2H92_05425	COG3832	glyoxalase III activity
C2H92_05460	COG4195	phage-related replication protein
C2H92_05480	COG0346	lactoylglutathione lyase activity
C2H92_05495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2H92_05500	COG1388	LysM domain
C2H92_05505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2H92_05510	COG4224	UPF0291 protein
C2H92_05515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2H92_05525	COG3763	UPF0154 protein
C2H92_05535	COG0785	Cytochrome C biogenesis protein
C2H92_05540	COG2201	protein-glutamate methylesterase activity
C2H92_05545	COG4846	Membrane protein involved in cytochrome C biogenesis
C2H92_05555	COG0071	Belongs to the small heat shock protein (HSP20) family
C2H92_05570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C2H92_05575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_05595	COG0824	Thioesterase
C2H92_05605	COG4841	protein insertion into membrane
C2H92_05610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C2H92_05615	COG1832	CoA-binding protein
C2H92_05625	COG0187	DNA topoisomerase II activity
C2H92_05640	COG1115	amino acid carrier protein
C2H92_05645	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C2H92_05665	COG5520	Belongs to the glycosyl hydrolase 30 family
C2H92_05670	COG3507	Belongs to the glycosyl hydrolase 43 family
C2H92_05680	COG2246	polysaccharide biosynthetic process
C2H92_05685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C2H92_05690	COG0586	Pfam SNARE associated Golgi protein
C2H92_05695	COG2404	hydrolase activity, acting on ester bonds
C2H92_05700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C2H92_05705	COG1024	Enoyl-CoA hydratase
C2H92_05710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C2H92_05715	COG0511	ligase activity, forming carbon-carbon bonds
C2H92_05720	COG0439	Biotin carboxylase
C2H92_05725	COG0318	PFAM AMP-dependent synthetase and ligase
C2H92_05730	COG1960	acyl-CoA dehydrogenase activity
C2H92_05740	COG1649	PFAM Uncharacterised BCR, COG1649
C2H92_05765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2H92_05770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2H92_05775	COG2027	D-alanyl-D-alanine carboxypeptidase
C2H92_05785	COG0534	Mate efflux family protein
C2H92_05800	COG0582	viral genome integration into host DNA
C2H92_05805	COG0166	Belongs to the GPI family
C2H92_05810	COG0405	Gamma-glutamyltransferase
C2H92_05815	COG0583	DNA-binding transcription factor activity
C2H92_05820	COG0604	alcohol dehydrogenase
C2H92_05825	COG0493	'glutamate synthase
C2H92_05830	COG0067	glutamate synthase
C2H92_05830	COG0069	glutamate synthase activity
C2H92_05830	COG0070	glutamate synthase
C2H92_05835	COG0583	DNA-binding transcription factor activity
C2H92_05840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C2H92_05860	COG0300	oxidoreductase activity
C2H92_05865	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C2H92_05875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_05890	COG1131	(ABC) transporter
C2H92_05900	COG2814	Major facilitator Superfamily
C2H92_05905	COG1070	Carbohydrate kinase
C2H92_05910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C2H92_05915	COG0243	molybdopterin cofactor binding
C2H92_05925	COG4305	rare lipoprotein A
C2H92_05930	COG3619	membrane
C2H92_05940	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_05945	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_05995	COG1070	Carbohydrate kinase
C2H92_06010	COG3507	Belongs to the glycosyl hydrolase 43 family
C2H92_06015	COG2211	Major facilitator Superfamily
C2H92_06035	COG0135	phosphoribosylanthranilate isomerase activity
C2H92_06065	COG3397	chitin binding
C2H92_06075	COG2318	DinB family
C2H92_06085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_06100	COG0596	Alpha beta hydrolase
C2H92_06130	COG0457	Tetratricopeptide repeat
C2H92_06165	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_06170	COG1733	regulation of RNA biosynthetic process
C2H92_06175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2H92_06180	COG0662	Cupin 2, conserved barrel domain protein
C2H92_06180	COG2207	Transcriptional regulator
C2H92_06185	COG0456	acetyltransferase
C2H92_06190	COG1309	transcriptional regulator
C2H92_06195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2H92_06200	COG3708	Transcriptional regulator
C2H92_06205	COG2378	regulation of single-species biofilm formation
C2H92_06215	COG0640	Transcriptional regulator
C2H92_06220	COG0741	lytic transglycosylase activity
C2H92_06225	COG2322	membrane
C2H92_06240	COG1619	proteins homologs of microcin C7 resistance protein MccF
C2H92_06245	COG3239	Fatty acid desaturase
C2H92_06250	COG4585	Histidine kinase
C2H92_06255	COG2197	response regulator
C2H92_06265	COG3584	3D domain protein
C2H92_06265	COG1388	LysM domain
C2H92_06270	COG0514	ATP-dependent DNA helicase (RecQ)
C2H92_06280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C2H92_06285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2H92_06300	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_06305	COG1657	PFAM Prenyltransferase squalene oxidase
C2H92_06310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C2H92_06315	COG0733	neurotransmitter:sodium symporter activity
C2H92_06320	COG0385	Bile acid
C2H92_06325	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2H92_06330	COG0567	Dehydrogenase, E1 component
C2H92_06335	COG4548	von Willebrand factor, type A
C2H92_06340	COG0714	Associated with various cellular activities
C2H92_06345	COG2032	superoxide dismutase activity
C2H92_06350	COG1388	LysM domain
C2H92_06350	COG0791	NLP P60 protein
C2H92_06355	COG1819	glycosyl
C2H92_06360	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C2H92_06365	COG0534	Mate efflux family protein
C2H92_06370	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_06375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C2H92_06380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C2H92_06390	COG2962	Rard protein
C2H92_06415	COG1733	regulation of RNA biosynthetic process
C2H92_06420	COG0778	Nitroreductase
C2H92_06425	COG0400	carboxylic ester hydrolase activity
C2H92_06430	COG0346	lactoylglutathione lyase activity
C2H92_06440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2H92_06445	COG3409	Peptidoglycan-binding domain 1 protein
C2H92_06445	COG0793	Belongs to the peptidase S41A family
C2H92_06450	COG2226	methyltransferase
C2H92_06460	COG1876	peptidase activity
C2H92_06465	COG0813	purine-nucleoside phosphorylase activity
C2H92_06495	COG1309	transcriptional regulator
C2H92_06500	COG2814	Major facilitator Superfamily
C2H92_06515	COG0671	phosphoesterase, PA-phosphatase related
C2H92_06535	COG4479	Belongs to the UPF0346 family
C2H92_06545	COG1509	lysine 2,3-aminomutase activity
C2H92_06550	COG0456	acetyltransferase
C2H92_06555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2H92_06565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C2H92_06580	COG0456	acetyltransferase
C2H92_06585	COG0463	Glycosyl transferase, family 2
C2H92_06600	COG4641	Protein conserved in bacteria
C2H92_06605	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C2H92_06610	COG1086	Polysaccharide biosynthesis protein
C2H92_06620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C2H92_06625	COG1846	Transcriptional regulator
C2H92_06630	COG0534	Mate efflux family protein
C2H92_06640	COG4698	Protein conserved in bacteria
C2H92_06645	COG2755	lipolytic protein G-D-S-L family
C2H92_06650	COG1999	signal sequence binding
C2H92_06660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C2H92_06665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C2H92_06670	COG1272	protein, Hemolysin III
C2H92_06675	COG0204	Acyl-transferase
C2H92_06680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C2H92_06690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C2H92_06700	COG2136	Putative SAM-dependent methyltransferase
C2H92_06700	COG2521	methyltransferase
C2H92_06710	COG0129	dihydroxy-acid dehydratase activity
C2H92_06715	COG1413	lyase activity
C2H92_06720	COG1418	mRNA catabolic process
C2H92_06725	COG0386	Belongs to the glutathione peroxidase family
C2H92_06730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C2H92_06735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C2H92_06740	COG1278	Cold shock
C2H92_06760	COG0328	RNA-DNA hybrid ribonuclease activity
C2H92_06765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C2H92_06770	COG0328	RNA-DNA hybrid ribonuclease activity
C2H92_06780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C2H92_06795	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C2H92_06805	COG1755	Isoprenylcysteine carboxyl methyltransferase
C2H92_06810	COG3424	synthase
C2H92_06815	COG2233	PERMEase
C2H92_06820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C2H92_06825	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C2H92_06835	COG0800	Aldolase
C2H92_06840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H92_06845	COG1609	Transcriptional regulator
C2H92_06850	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C2H92_06855	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_06860	COG1199	ATP-dependent helicase activity
C2H92_06875	COG0116	Belongs to the methyltransferase superfamily
C2H92_06890	COG4474	Belongs to the UPF0398 family
C2H92_06900	COG3359	exonuclease
C2H92_06905	COG1111	helicase
C2H92_06905	COG1205	dead DEAH box helicase
C2H92_06910	COG2190	(PTS) system
C2H92_06915	COG0071	Belongs to the small heat shock protein (HSP20) family
C2H92_06950	COG3331	DNA recombination
C2H92_06955	COG4499	WXG100 protein secretion system (Wss), protein YukC
C2H92_06955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2H92_06965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C2H92_06970	COG3935	DnaD domain protein
C2H92_06975	COG0017	Asparaginyl-tRNA synthetase
C2H92_06980	COG0436	Aminotransferase
C2H92_07000	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C2H92_07005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C2H92_07010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C2H92_07015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C2H92_07015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C2H92_07020	COG0617	tRNA 3'-terminal CCA addition
C2H92_07025	COG0438	transferase activity, transferring glycosyl groups
C2H92_07030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C2H92_07035	COG1803	Methylglyoxal synthase
C2H92_07040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C2H92_07045	COG1694	Mazg nucleotide pyrophosphohydrolase
C2H92_07050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2H92_07060	COG4347	Protein of unknown function (DUF1405)
C2H92_07065	COG2010	Cytochrome c
C2H92_07065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C2H92_07070	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C2H92_07075	COG0723	plastoquinol--plastocyanin reductase activity
C2H92_07085	COG5582	Belongs to the UPF0302 family
C2H92_07090	COG0457	Tetratricopeptide repeat
C2H92_07095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C2H92_07105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C2H92_07110	COG0159	tryptophan synthase activity
C2H92_07115	COG0133	tryptophan synthase activity
C2H92_07120	COG0135	phosphoribosylanthranilate isomerase activity
C2H92_07130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C2H92_07135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C2H92_07140	COG4401	Chorismate mutase type I
C2H92_07145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C2H92_07150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C2H92_07155	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C2H92_07160	COG0105	UTP biosynthetic process
C2H92_07165	COG0142	geranyltranstransferase activity
C2H92_07170	COG2226	methyltransferase
C2H92_07175	COG0142	geranyltranstransferase activity
C2H92_07185	COG0302	gtp cyclohydrolase
C2H92_07190	COG0776	regulation of translation
C2H92_07195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C2H92_07210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C2H92_07215	COG1160	GTP binding
C2H92_07240	COG1304	FMN binding
C2H92_07245	COG0539	negative regulation of cytoplasmic translation
C2H92_07250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C2H92_07260	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C2H92_07265	COG2959	enzyme of heme biosynthesis
C2H92_07270	COG3773	Cell wall hydrolase
C2H92_07270	COG3409	Peptidoglycan-binding domain 1 protein
C2H92_07280	COG0492	ferredoxin-NADP+ reductase activity
C2H92_07285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2H92_07290	COG4862	establishment of competence for transformation
C2H92_07295	COG1408	metallophosphoesterase
C2H92_07305	COG1388	LysM domain
C2H92_07310	COG1266	CAAX protease self-immunity
C2H92_07315	COG0514	ATP-dependent DNA helicase (RecQ)
C2H92_07320	COG4955	Helix-turn-helix domain
C2H92_07325	COG1141	Ferredoxin
C2H92_07330	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C2H92_07340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C2H92_07345	COG0710	3-dehydroquinate dehydratase activity
C2H92_07355	COG1595	DNA-templated transcription, initiation
C2H92_07360	COG5002	protein histidine kinase activity
C2H92_07365	COG0745	RESPONSE REGULATOR receiver
C2H92_07370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2H92_07380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_07385	COG1187	pseudouridine synthase activity
C2H92_07390	COG0700	Nucleoside recognition
C2H92_07395	COG2715	membrane protein required for spore maturation
C2H92_07400	COG1686	Belongs to the peptidase S11 family
C2H92_07410	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C2H92_07415	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C2H92_07425	COG1547	Domain of unknown function (DUF309)
C2H92_07430	COG0456	acetyltransferase
C2H92_07435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C2H92_07440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C2H92_07440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C2H92_07445	COG0307	riboflavin synthase, alpha
C2H92_07450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2H92_07450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2H92_07460	COG0681	Belongs to the peptidase S26 family
C2H92_07465	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C2H92_07470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C2H92_07475	COG4086	secreted protein
C2H92_07480	COG0019	diaminopimelate decarboxylase activity
C2H92_07485	COG0697	spore germination
C2H92_07500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C2H92_07520	COG1191	sigma factor activity
C2H92_07525	COG2172	sigma factor antagonist activity
C2H92_07530	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_07535	COG1686	Belongs to the peptidase S11 family
C2H92_07540	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C2H92_07545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C2H92_07550	COG4974	Belongs to the 'phage' integrase family
C2H92_07560	COG0735	belongs to the Fur family
C2H92_07565	COG1300	Membrane
C2H92_07575	COG0281	malic enzyme
C2H92_07580	COG1757	Na H antiporter
C2H92_07585	COG1027	Aspartate ammonia-lyase
C2H92_07590	COG0252	asparaginase activity
C2H92_07595	COG1396	sequence-specific DNA binding
C2H92_07605	COG0494	nUDIX hydrolase
C2H92_07615	COG0667	Aldo Keto reductase
C2H92_07625	COG1073	alpha beta
C2H92_07635	COG4918	Iron-sulphur cluster biosynthesis
C2H92_07640	COG0456	acetyltransferase
C2H92_07640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C2H92_07645	COG2329	Antibiotic biosynthesis monooxygenase
C2H92_07650	COG0456	acetyltransferase
C2H92_07660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2H92_07670	COG2211	Major facilitator Superfamily
C2H92_07680	COG0346	lactoylglutathione lyase activity
C2H92_07685	COG1072	(Pantothenic acid kinase))
C2H92_07690	COG3048	D-serine ammonia-lyase activity
C2H92_07695	COG0300	oxidoreductase activity
C2H92_07700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2H92_07705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C2H92_07710	COG4187	Peptidase family M20/M25/M40
C2H92_07715	COG1902	pentaerythritol trinitrate reductase activity
C2H92_07720	COG0596	Alpha beta hydrolase
C2H92_07730	COG1234	tRNA 3'-trailer cleavage
C2H92_07735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C2H92_07745	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C2H92_07750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2H92_07760	COG0706	membrane insertase activity
C2H92_07765	COG3361	conserved protein (COG2071)
C2H92_07770	COG2195	Cleaves the N-terminal amino acid of tripeptides
C2H92_07780	COG0346	lactoylglutathione lyase activity
C2H92_07785	COG1376	ErfK ybiS ycfS ynhG family protein
C2H92_07790	COG4129	membrane
C2H92_07795	COG1126	abc transporter atp-binding protein
C2H92_07800	COG0765	amino acid transport
C2H92_07805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H92_07815	COG1597	lipid kinase activity
C2H92_07820	COG2814	Major facilitator Superfamily
C2H92_07825	COG0789	Transcriptional regulator
C2H92_07825	COG4978	Transcriptional regulator
C2H92_07835	COG0022	dehydrogenase e1 component
C2H92_07840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C2H92_07845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2H92_07850	COG3426	butyrate kinase activity
C2H92_07855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2H92_07860	COG0280	phosphate acetyltransferase
C2H92_07865	COG3829	transcription factor binding
C2H92_07865	COG3290	protein histidine kinase activity
C2H92_07875	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C2H92_07880	COG2079	MmgE PrpD family protein
C2H92_07890	COG1960	acyl-CoA dehydrogenase activity
C2H92_07895	COG1250	3-hydroxyacyl-CoA dehydrogenase
C2H92_07900	COG0183	Belongs to the thiolase family
C2H92_07910	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H92_07920	COG1902	pentaerythritol trinitrate reductase activity
C2H92_07930	COG0745	RESPONSE REGULATOR receiver
C2H92_07935	COG0750	zinc metalloprotease
C2H92_07940	COG0497	DNA recombination
C2H92_07945	COG1438	arginine binding
C2H92_07950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C2H92_07960	COG0142	geranyltranstransferase activity
C2H92_07965	COG1722	exodeoxyribonuclease VII activity
C2H92_07970	COG1570	exodeoxyribonuclease VII activity
C2H92_07975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C2H92_07980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C2H92_07985	COG1302	Protein conserved in bacteria
C2H92_07990	COG0439	Biotin carboxylase
C2H92_07995	COG0511	ligase activity, forming carbon-carbon bonds
C2H92_08035	COG3854	ATPases associated with a variety of cellular activities
C2H92_08045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C2H92_08050	COG0006	proline dipeptidase activity
C2H92_08055	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C2H92_08065	COG3872	metal-dependent enzyme
C2H92_08075	COG1752	Esterase of the alpha-beta hydrolase superfamily
C2H92_08080	COG1321	iron dependent repressor
C2H92_08085	COG0095	Lipoate-protein ligase
C2H92_08090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2H92_08095	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C2H92_08105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C2H92_08110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C2H92_08125	COG1396	sequence-specific DNA binding
C2H92_08135	COG0681	Belongs to the peptidase S26 family
C2H92_08160	COG4940	Competence protein ComGF
C2H92_08170	COG4970	Tfp pilus assembly protein FimT
C2H92_08175	COG4537	Required for transformation and DNA binding
C2H92_08180	COG1459	type II secretion system
C2H92_08185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2H92_08190	COG0517	IMP dehydrogenase activity
C2H92_08195	COG0598	Magnesium transport protein CorA
C2H92_08200	COG1253	flavin adenine dinucleotide binding
C2H92_08205	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_08215	COG1393	Belongs to the ArsC family
C2H92_08225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2H92_08235	COG0011	TIGRFAM Protein of
C2H92_08245	COG2866	Carboxypeptidase
C2H92_08255	COG1940	carbohydrate kinase activity
C2H92_08260	COG4483	Protein conserved in bacteria
C2H92_08265	COG0705	Rhomboid family
C2H92_08265	COG0457	Tetratricopeptide repeat
C2H92_08275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C2H92_08285	COG0438	transferase activity, transferring glycosyl groups
C2H92_08300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C2H92_08305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C2H92_08310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C2H92_08315	COG0581	inorganic phosphate transmembrane transporter activity
C2H92_08320	COG0573	inorganic phosphate transmembrane transporter activity
C2H92_08325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C2H92_08330	COG0768	penicillin binding
C2H92_08340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C2H92_08345	COG2839	Protein conserved in bacteria
C2H92_08350	COG5521	maltodextrose utilization protein MalA
C2H92_08355	COG1388	LysM domain
C2H92_08360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C2H92_08365	COG4709	membrane
C2H92_08370	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C2H92_08385	COG0735	belongs to the Fur family
C2H92_08390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2H92_08400	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C2H92_08415	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C2H92_08420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C2H92_08425	COG2384	SAM-dependent methyltransferase
C2H92_08430	COG2010	Cytochrome c
C2H92_08435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C2H92_08445	COG1671	Belongs to the UPF0178 family
C2H92_08450	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C2H92_08455	COG0517	IMP dehydrogenase activity
C2H92_08465	COG0752	glycyl-tRNA synthetase alpha subunit
C2H92_08470	COG1381	Involved in DNA repair and RecF pathway recombination
C2H92_08485	COG0295	cytidine deaminase activity
C2H92_08490	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C2H92_08495	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C2H92_08500	COG1480	7TM receptor with intracellular HD hydrolase
C2H92_08510	COG0561	phosphatase activity
C2H92_08525	COG4864	UPF0365 protein
C2H92_08530	COG1030	water channel activity
C2H92_08535	COG1610	YqeY-like protein
C2H92_08545	COG1283	sodium-dependent phosphate transmembrane transporter activity
C2H92_08550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C2H92_08555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C2H92_08560	COG2264	protein methyltransferase activity
C2H92_08565	COG0484	heat shock protein binding
C2H92_08575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C2H92_08580	COG1420	regulation of RNA biosynthetic process
C2H92_08585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2H92_08590	COG0481	GTPase activity
C2H92_08600	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H92_08605	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2H92_08610	COG0268	Binds directly to 16S ribosomal RNA
C2H92_08615	COG1466	dna polymerase III delta subunit
C2H92_08625	COG0658	competence protein
C2H92_08625	COG2333	competence protein COMEC
C2H92_08630	COG2131	deaminase
C2H92_08635	COG1596	polysaccharide export
C2H92_08635	COG1555	photosystem II stabilization
C2H92_08640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C2H92_08645	COG2226	methyltransferase
C2H92_08650	COG0799	negative regulation of ribosome biogenesis
C2H92_08655	COG1713	HD superfamily hydrolase involved in NAD metabolism
C2H92_08660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C2H92_08665	COG1534	Rna-binding protein
C2H92_08670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C2H92_08675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C2H92_08680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C2H92_08690	COG2755	lipolytic protein G-D-S-L family
C2H92_08695	COG5632	N-Acetylmuramoyl-L-alanine amidase
C2H92_08695	COG3409	Peptidoglycan-binding domain 1 protein
C2H92_08700	COG0398	Pfam SNARE associated Golgi protein
C2H92_08705	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C2H92_08715	COG3209	COG3209 Rhs family protein
C2H92_08730	COG3223	Belongs to the PsiE family
C2H92_08735	COG5002	protein histidine kinase activity
C2H92_08735	COG0642	Histidine kinase
C2H92_08740	COG0745	RESPONSE REGULATOR receiver
C2H92_08745	COG2311	Membrane
C2H92_08755	COG0454	-acetyltransferase
C2H92_08760	COG2249	NAD(P)H dehydrogenase (quinone) activity
C2H92_08770	COG1846	Transcriptional regulator
C2H92_08775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2H92_08795	COG0457	Tetratricopeptide repeat
C2H92_08860	COG3443	Belongs to the bacterial solute-binding protein 9 family
C2H92_08865	COG4991	sh3 domain protein
C2H92_08870	COG4991	sh3 domain protein
C2H92_08895	COG0693	protein deglycase activity
C2H92_08900	COG1621	beta-fructofuranosidase activity
C2H92_08905	COG3716	PTS system mannose fructose sorbose family IID component
C2H92_08910	COG3715	PTS system
C2H92_08915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H92_08920	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H92_08925	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C2H92_08925	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C2H92_08930	COG1113	amino acid transport
C2H92_08940	COG1378	Sugar-specific transcriptional regulator TrmB
C2H92_08955	COG2755	lipolytic protein G-D-S-L family
C2H92_08955	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C2H92_08965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C2H92_08965	COG2124	cytochrome p450
C2H92_08970	COG1309	transcriptional regulator
C2H92_08985	COG2116	formate transmembrane transporter activity
C2H92_08990	COG5609	conserved protein (DUF2294)
C2H92_08995	COG3383	formate dehydrogenase (NAD+) activity
C2H92_09000	COG2427	Protein of unknown function (DUF1641)
C2H92_09010	COG0626	cystathionine gamma-synthase activity
C2H92_09015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2H92_09020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C2H92_09025	COG2226	methyltransferase
C2H92_09040	COG0768	penicillin binding
C2H92_09045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2H92_09050	COG0572	uridine kinase
C2H92_09055	COG0826	peptidase U32
C2H92_09060	COG0826	peptidase U32
C2H92_09065	COG4122	O-methyltransferase activity
C2H92_09070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C2H92_09075	COG3906	Belongs to the UPF0473 family
C2H92_09080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C2H92_09085	COG4472	Bacterial protein of unknown function (DUF965)
C2H92_09090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C2H92_09095	COG0628	permease
C2H92_09100	COG1126	abc transporter atp-binding protein
C2H92_09105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H92_09115	COG0765	amino acid transport
C2H92_09130	COG3881	PFAM PRC-barrel domain
C2H92_09135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C2H92_09140	COG0457	Tetratricopeptide repeat
C2H92_09145	COG0482	sulfurtransferase activity
C2H92_09150	COG1104	cysteine desulfurase activity
C2H92_09155	COG1959	2 iron, 2 sulfur cluster binding
C2H92_09160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C2H92_09165	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C2H92_09175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C2H92_09180	COG0124	histidyl-tRNA synthetase
C2H92_09190	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H92_09190	COG3103	Sh3 type 3 domain protein
C2H92_09190	COG4991	sh3 domain protein
C2H92_09195	COG1490	D-aminoacyl-tRNA deacylase activity
C2H92_09200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C2H92_09205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C2H92_09210	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C2H92_09210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C2H92_09215	COG5416	Lipopolysaccharide assembly protein A domain
C2H92_09220	COG0490	domain, Protein
C2H92_09225	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2H92_09225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2H92_09235	COG2244	polysaccharide biosynthetic process
C2H92_09240	COG2323	membrane
C2H92_09250	COG1862	Preprotein translocase
C2H92_09255	COG0343	queuine tRNA-ribosyltransferase activity
C2H92_09260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C2H92_09270	COG2255	four-way junction helicase activity
C2H92_09275	COG0632	four-way junction helicase activity
C2H92_09285	COG2814	Major facilitator Superfamily
C2H92_09290	COG0673	inositol 2-dehydrogenase activity
C2H92_09295	COG2112	serine threonine protein kinase
C2H92_09305	COG1115	amino acid carrier protein
C2H92_09310	COG0217	transcriptional regulatory protein
C2H92_09320	COG1388	LysM domain
C2H92_09325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C2H92_09330	COG0157	Belongs to the NadC ModD family
C2H92_09335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C2H92_09340	COG1104	cysteine desulfurase activity
C2H92_09345	COG1827	regulation of RNA biosynthetic process
C2H92_09350	COG0077	Prephenate dehydratase
C2H92_09355	COG4492	Belongs to the UPF0735 family
C2H92_09360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C2H92_09365	COG3290	protein histidine kinase activity
C2H92_09370	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C2H92_09375	COG2868	ribosomal protein
C2H92_09380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C2H92_09385	COG1994	Peptidase M50
C2H92_09390	COG0739	heme binding
C2H92_09395	COG2894	cell division
C2H92_09400	COG0850	regulation of cytokinetic process
C2H92_09405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C2H92_09415	COG1077	Cell shape determining protein MreB Mrl
C2H92_09425	COG0424	maF-like protein
C2H92_09435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C2H92_09440	COG0285	dihydrofolate synthase activity
C2H92_09445	COG0525	valine-tRNA ligase activity
C2H92_09455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C2H92_09460	COG1388	LysM domain
C2H92_09465	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C2H92_09470	COG0113	porphobilinogen synthase activity
C2H92_09475	COG1587	Uroporphyrinogen-III synthase
C2H92_09480	COG0181	hydroxymethylbilane synthase activity
C2H92_09485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2H92_09490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C2H92_09500	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C2H92_09505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C2H92_09510	COG0470	DNA polymerase III
C2H92_09510	COG1067	ATP-dependent peptidase activity
C2H92_09515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C2H92_09520	COG0544	peptidyl-prolyl cis-trans isomerase activity
C2H92_09525	COG0457	Tetratricopeptide repeat
C2H92_09525	COG1477	protein flavinylation
C2H92_09530	COG0066	3-isopropylmalate dehydratase activity
C2H92_09535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C2H92_09540	COG0473	3-isopropylmalate dehydrogenase activity
C2H92_09545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C2H92_09550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C2H92_09555	COG0440	acetolactate synthase activity
C2H92_09560	COG0028	Belongs to the TPP enzyme family
C2H92_09570	COG0454	-acetyltransferase
C2H92_09575	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
C2H92_09585	COG0622	Phosphoesterase
C2H92_09590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C2H92_09595	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C2H92_09600	COG5401	PFAM Sporulation and spore germination
C2H92_09605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C2H92_09615	COG2197	response regulator
C2H92_09620	COG0824	Thioesterase
C2H92_09625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C2H92_09635	COG2009	succinate dehydrogenase
C2H92_09640	COG1719	4-vinyl reductase, 4VR
C2H92_09645	COG0527	aspartate kinase activity
C2H92_09650	COG0322	excinuclease ABC activity
C2H92_09655	COG3118	belongs to the thioredoxin family
C2H92_09660	COG3534	alpha-L-arabinofuranosidase
C2H92_09665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C2H92_09670	COG2086	electron transfer activity
C2H92_09675	COG1024	Enoyl-CoA hydratase
C2H92_09680	COG1309	transcriptional regulator
C2H92_09685	COG0318	PFAM AMP-dependent synthetase and ligase
C2H92_09690	COG3766	membrane
C2H92_09705	COG1286	toxin biosynthetic process
C2H92_09710	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C2H92_09715	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C2H92_09720	COG0072	phenylalanine-tRNA ligase activity
C2H92_09720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2H92_09735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2H92_09750	COG0277	FAD linked oxidase domain protein
C2H92_09755	COG0247	lactate metabolic process
C2H92_09760	COG0346	lactoylglutathione lyase activity
C2H92_09780	COG1695	Transcriptional regulator
C2H92_09790	COG0395	ABC-type sugar transport system, permease component
C2H92_09795	COG1175	transmembrane transport
C2H92_09800	COG1653	transport
C2H92_09805	COG0371	Dehydrogenase
C2H92_09810	COG0647	UMP catabolic process
C2H92_09815	COG0235	Class ii aldolase
C2H92_09820	COG1069	ribulokinase activity
C2H92_09825	COG2160	L-arabinose isomerase activity
C2H92_09830	COG3507	Belongs to the glycosyl hydrolase 43 family
C2H92_09835	COG1363	Peptidase, m42
C2H92_09845	COG3326	Membrane
C2H92_09850	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C2H92_09855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C2H92_09860	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C2H92_09880	COG1346	cytolysis
C2H92_09885	COG1380	Effector of murein hydrolase LrgA
C2H92_09890	COG3279	Response regulator of the LytR AlgR family
C2H92_09895	COG3275	phosphorelay sensor kinase activity
C2H92_09900	COG1011	Hydrolase
C2H92_09905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C2H92_09915	COG0398	Pfam SNARE associated Golgi protein
C2H92_09920	COG1484	DNA-dependent DNA replication
C2H92_09925	COG3611	Membrane attachment protein
C2H92_09930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C2H92_09935	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C2H92_09940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C2H92_09945	COG1733	regulation of RNA biosynthetic process
C2H92_09950	COG2814	Major facilitator Superfamily
C2H92_09955	COG0656	L-ascorbic acid biosynthetic process
C2H92_09960	COG0237	dephospho-CoA kinase activity
C2H92_09965	COG1971	Probably functions as a manganese efflux pump
C2H92_09970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C2H92_09985	COG0745	RESPONSE REGULATOR receiver
C2H92_09990	COG0039	L-malate dehydrogenase activity
C2H92_09995	COG0538	isocitrate dehydrogenase activity
C2H92_10000	COG0372	Belongs to the citrate synthase family
C2H92_10005	COG2707	UPF0756 membrane protein
C2H92_10010	COG0628	permease
C2H92_10015	COG3030	protein affecting phage T7 exclusion by the F plasmid
C2H92_10020	COG0469	pyruvate kinase activity
C2H92_10025	COG0205	6-phosphofructokinase activity
C2H92_10030	COG0825	malonyl-CoA metabolic process
C2H92_10035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C2H92_10040	COG0281	malic enzyme
C2H92_10045	COG0587	DNA-directed DNA polymerase activity
C2H92_10065	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C2H92_10075	COG4109	DRTGG domain
C2H92_10080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C2H92_10095	COG0165	Argininosuccinate lyase
C2H92_10100	COG0137	argininosuccinate synthase activity
C2H92_10105	COG0521	Mo-molybdopterin cofactor biosynthetic process
C2H92_10110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C2H92_10115	COG0827	DNA restriction-modification system
C2H92_10120	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C2H92_10125	COG3874	Sporulation protein YtfJ
C2H92_10135	COG1714	RDD family
C2H92_10140	COG0616	signal peptide processing
C2H92_10145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C2H92_10150	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C2H92_10155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C2H92_10165	COG0301	tRNA thio-modification
C2H92_10170	COG1104	cysteine desulfurase activity
C2H92_10175	COG1114	Component of the transport system for branched-chain amino acids
C2H92_10180	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C2H92_10185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C2H92_10190	COG1309	transcriptional regulator
C2H92_10195	COG1956	GAF domain-containing protein
C2H92_10200	COG2203	Gaf domain
C2H92_10200	COG2199	diguanylate cyclase activity
C2H92_10215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C2H92_10225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C2H92_10230	COG0454	-acetyltransferase
C2H92_10235	COG0517	IMP dehydrogenase activity
C2H92_10240	COG0123	including yeast histone deacetylase and acetoin utilization protein
C2H92_10245	COG1360	Flagellar Motor Protein
C2H92_10250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C2H92_10255	COG1609	Transcriptional regulator
C2H92_10260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C2H92_10260	COG1605	Chorismate mutase
C2H92_10270	COG3118	belongs to the thioredoxin family
C2H92_10275	COG4980	gas vesicle protein
C2H92_10280	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C2H92_10285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C2H92_10290	COG1674	ftsk spoiiie
C2H92_10295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2H92_10305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_10315	COG1363	Peptidase, m42
C2H92_10320	COG5584	Small secreted protein
C2H92_10325	COG0281	malic enzyme
C2H92_10335	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C2H92_10345	COG0510	thiamine kinase activity
C2H92_10350	COG1523	belongs to the glycosyl hydrolase 13 family
C2H92_10355	COG1597	lipid kinase activity
C2H92_10365	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C2H92_10370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2H92_10375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2H92_10380	COG2252	PERMEase
C2H92_10385	COG4473	ABC transporter
C2H92_10390	COG1131	(ABC) transporter
C2H92_10395	COG1349	DNA-binding transcription factor activity
C2H92_10400	COG1187	pseudouridine synthase activity
C2H92_10405	COG2244	polysaccharide biosynthetic process
C2H92_10410	COG2081	HI0933 family
C2H92_10415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C2H92_10425	COG5578	integral membrane protein
C2H92_10430	COG0673	inositol 2-dehydrogenase activity
C2H92_10435	COG1653	transport
C2H92_10440	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C2H92_10445	COG4209	transmembrane transport
C2H92_10450	COG2207	Transcriptional regulator
C2H92_10455	COG1653	transport
C2H92_10460	COG0395	ABC-type sugar transport system, permease component
C2H92_10465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2H92_10470	COG2124	cytochrome p450
C2H92_10475	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C2H92_10485	COG0156	8-amino-7-oxononanoate synthase activity
C2H92_10490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C2H92_10500	COG1073	alpha beta
C2H92_10505	COG1609	Transcriptional regulator
C2H92_10510	COG1653	transport
C2H92_10515	COG1175	transmembrane transport
C2H92_10520	COG0395	ABC-type sugar transport system, permease component
C2H92_10525	COG1486	melibiose metabolic process
C2H92_10530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2H92_10535	COG0495	leucyl-tRNA aminoacylation
C2H92_10545	COG2202	Pas domain
C2H92_10545	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_10550	COG2814	Major facilitator Superfamily
C2H92_10555	COG2433	Pfam Transposase IS66
C2H92_10565	COG1136	(ABC) transporter
C2H92_10570	COG2205	protein histidine kinase activity
C2H92_10575	COG0745	RESPONSE REGULATOR receiver
C2H92_10580	COG0577	efflux transmembrane transporter activity
C2H92_10585	COG1136	(ABC) transporter
C2H92_10600	COG1131	(ABC) transporter
C2H92_10605	COG1725	Transcriptional regulator
C2H92_10615	COG1242	4 iron, 4 sulfur cluster binding
C2H92_10620	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C2H92_10630	COG2267	carboxylic ester hydrolase activity
C2H92_10635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2H92_10640	COG1113	amino acid transport
C2H92_10645	COG0367	asparagine synthase
C2H92_10650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C2H92_10655	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C2H92_10665	COG1506	peptidase
C2H92_10670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2H92_10675	COG1116	anion transmembrane transporter activity
C2H92_10680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2H92_10685	COG0494	nUDIX hydrolase
C2H92_10690	COG4824	toxin secretion phage lysis holin
C2H92_10695	COG0783	Belongs to the Dps family
C2H92_10710	COG1854	S-ribosylhomocysteine lyase activity
C2H92_10715	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C2H92_10720	COG0288	reversible hydration of carbon dioxide
C2H92_10725	COG0254	rRNA binding
C2H92_10730	COG1271	oxidase subunit
C2H92_10735	COG1294	oxidase, subunit
C2H92_10745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2H92_10750	COG1321	iron dependent repressor
C2H92_10750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2H92_10755	COG1121	(ABC) transporter
C2H92_10760	COG0803	Belongs to the bacterial solute-binding protein 9 family
C2H92_10765	COG4948	Mandelate Racemase Muconate Lactonizing
C2H92_10770	COG0318	PFAM AMP-dependent synthetase and ligase
C2H92_10775	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C2H92_10780	COG0596	Alpha beta hydrolase
C2H92_10785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C2H92_10795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2H92_10800	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C2H92_10805	COG0058	SHG alpha-glucan phosphorylase activity
C2H92_10810	COG0297	glycogen (starch) synthase activity
C2H92_10815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C2H92_10820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C2H92_10825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C2H92_10950	COG3859	Proton-coupled thiamine transporter YuaJ
C2H92_10960	COG2268	Band 7 protein
C2H92_10965	COG1585	Membrane protein implicated in regulation of membrane protease activity
C2H92_10970	COG2318	DinB family
C2H92_10980	COG1454	alcohol dehydrogenase
C2H92_10985	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_10990	COG1510	regulation of RNA biosynthetic process
C2H92_11000	COG0569	domain protein
C2H92_11005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C2H92_11010	COG4682	membrane
C2H92_11015	COG1705	Flagellar rod assembly protein muramidase FlgJ
C2H92_11020	COG0477	Major facilitator Superfamily
C2H92_11030	COG5553	Cysteine dioxygenase type I
C2H92_11040	COG1968	undecaprenyl-diphosphatase activity
C2H92_11045	COG0628	permease
C2H92_11050	COG0673	inositol 2-dehydrogenase activity
C2H92_11055	COG4806	L-rhamnose isomerase
C2H92_11060	COG3254	rhamnose metabolic process
C2H92_11065	COG1070	Carbohydrate kinase
C2H92_11070	COG1349	DNA-binding transcription factor activity
C2H92_11075	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_11075	COG3347	Dehydrogenase
C2H92_11080	COG0840	transmembrane signaling receptor activity
C2H92_11085	COG0840	transmembrane signaling receptor activity
C2H92_11090	COG0840	transmembrane signaling receptor activity
C2H92_11095	COG0840	transmembrane signaling receptor activity
C2H92_11110	COG2070	2-Nitropropane dioxygenase
C2H92_11115	COG0432	Pfam Uncharacterised protein family UPF0047
C2H92_11125	COG0366	Alpha amylase catalytic
C2H92_11130	COG1253	flavin adenine dinucleotide binding
C2H92_11135	COG2738	Putative neutral zinc metallopeptidase
C2H92_11165	COG0166	Belongs to the GPI family
C2H92_11170	COG1979	alcohol dehydrogenase
C2H92_11175	COG1979	alcohol dehydrogenase
C2H92_11180	COG2155	Conserved Protein
C2H92_11185	COG1098	S1 RNA binding domain
C2H92_11190	COG0436	Aminotransferase
C2H92_11195	COG1522	sequence-specific DNA binding
C2H92_11200	COG2267	carboxylic ester hydrolase activity
C2H92_11215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C2H92_11220	COG2205	protein histidine kinase activity
C2H92_11230	COG5018	Exonuclease
C2H92_11240	COG2814	Major facilitator Superfamily
C2H92_11245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2H92_11250	COG3011	Protein conserved in bacteria
C2H92_11260	COG3290	protein histidine kinase activity
C2H92_11265	COG4565	transcriptional regulatory protein
C2H92_11270	COG1744	ABC transporter substrate-binding protein PnrA-like
C2H92_11275	COG3845	ABC transporter
C2H92_11280	COG4603	Belongs to the binding-protein-dependent transport system permease family
C2H92_11285	COG1079	Belongs to the binding-protein-dependent transport system permease family
C2H92_11290	COG3493	citrate carrier protein
C2H92_11300	COG2111	Na H antiporter
C2H92_11300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C2H92_11305	COG2111	Na H antiporter
C2H92_11310	COG1006	Multisubunit Na H antiporter MnhC subunit
C2H92_11315	COG0651	ATP synthesis coupled electron transport
C2H92_11320	COG1863	multisubunit Na H antiporter MnhE subunit
C2H92_11325	COG2212	antiporter activity
C2H92_11330	COG1320	monovalent cation:proton antiporter activity
C2H92_11335	COG2050	protein possibly involved in aromatic compounds catabolism
C2H92_11340	COG2197	response regulator
C2H92_11345	COG4585	Histidine kinase
C2H92_11370	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C2H92_11375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C2H92_11380	COG1335	isochorismatase
C2H92_11385	COG5506	Protein of unknown function (DUF1694)
C2H92_11400	COG0628	permease
C2H92_11410	COG1418	mRNA catabolic process
C2H92_11415	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_11425	COG1511	domain protein
C2H92_11430	COG1674	ftsk spoiiie
C2H92_11430	COG0433	COG0433 Predicted ATPase
C2H92_11440	COG5417	Belongs to the EsaB family
C2H92_11445	COG4842	Belongs to the WXG100 family
C2H92_11450	COG2508	Transcriptional regulator
C2H92_11450	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C2H92_11455	COG0686	Belongs to the AlaDH PNT family
C2H92_11460	COG5634	Uncharacterized conserved protein (DUF2278)
C2H92_11465	COG3251	PFAM MbtH domain protein
C2H92_11470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2H92_11475	COG1535	isochorismatase
C2H92_11475	COG3433	isochorismatase activity
C2H92_11480	COG1021	2,3-dihydroxybenzoate-AMP ligase
C2H92_11485	COG1169	isochorismate synthase
C2H92_11490	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_11495	COG2819	hydrolase of the alpha beta superfamily
C2H92_11500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C2H92_11505	COG1268	BioY protein
C2H92_11510	COG2056	Na+-H+ antiporter family
C2H92_11515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C2H92_11520	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C2H92_11525	COG3584	3D domain protein
C2H92_11540	COG1252	NADH dehydrogenase
C2H92_11545	COG0492	ferredoxin-NADP+ reductase activity
C2H92_11555	COG0516	GMP reductase activity
C2H92_11560	COG0316	Belongs to the HesB IscA family
C2H92_11565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C2H92_11570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2H92_11575	COG4844	belongs to the
C2H92_11580	COG1252	NADH dehydrogenase
C2H92_11585	COG4837	Protein of unknown function (DUF1462)
C2H92_11590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C2H92_11595	COG0823	Involved in the tonB-independent uptake of proteins
C2H92_11595	COG4946	Tricorn protease homolog
C2H92_11595	COG1506	peptidase
C2H92_11600	COG0083	homoserine kinase activity
C2H92_11605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C2H92_11615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C2H92_11620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C2H92_11625	COG0647	UMP catabolic process
C2H92_11630	COG2445	Protein of unknown function DUF86
C2H92_11635	COG4470	Protein conserved in bacteria
C2H92_11650	COG0739	heme binding
C2H92_11660	COG3377	Domain of unknown function (DUF1805)
C2H92_11665	COG0737	Belongs to the 5'-nucleotidase family
C2H92_11670	COG0730	response to heat
C2H92_11675	COG1801	Protein of unknown function DUF72
C2H92_11685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C2H92_11690	COG2508	Transcriptional regulator
C2H92_11695	COG2233	PERMEase
C2H92_11700	COG2233	PERMEase
C2H92_11705	COG3648	Uricase
C2H92_11705	COG3195	allantoin biosynthetic process
C2H92_11710	COG2351	hydroxyisourate hydrolase activity
C2H92_11725	COG2080	2 iron, 2 sulfur cluster binding
C2H92_11730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C2H92_11735	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C2H92_11740	COG2068	MobA-Related Protein
C2H92_11745	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C2H92_11750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C2H92_11755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2H92_11760	COG2356	endonuclease I
C2H92_11765	COG3842	ATPase activity
C2H92_11770	COG2188	Transcriptional regulator
C2H92_11775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H92_11780	COG0395	ABC-type sugar transport system, permease component
C2H92_11785	COG1175	transmembrane transport
C2H92_11790	COG1653	transport
C2H92_11795	COG2222	sugar isomerase
C2H92_11800	COG0322	excinuclease ABC activity
C2H92_11805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2H92_11820	COG0719	Fe-S assembly protein
C2H92_11825	COG0822	iron-sulfur transferase activity
C2H92_11830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C2H92_11835	COG0719	Fe-S assembly protein
C2H92_11840	COG0396	ATPase activity
C2H92_11850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2H92_11855	COG1464	Belongs to the NlpA lipoprotein family
C2H92_11860	COG2011	ABC-type metal ion transport system permease component
C2H92_11865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C2H92_11875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_11880	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C2H92_11890	COG0509	glycine decarboxylation via glycine cleavage system
C2H92_11895	COG1393	Belongs to the ArsC family
C2H92_11900	COG1960	acyl-CoA dehydrogenase activity
C2H92_11905	COG0183	Belongs to the thiolase family
C2H92_11910	COG1024	Enoyl-CoA hydratase
C2H92_11910	COG1250	3-hydroxyacyl-CoA dehydrogenase
C2H92_11920	COG0506	proline dehydrogenase activity
C2H92_11930	COG5577	PFAM Coat F domain
C2H92_11940	COG0477	Major facilitator Superfamily
C2H92_11945	COG1942	4-Oxalocrotonate Tautomerase
C2H92_11955	COG0583	DNA-binding transcription factor activity
C2H92_11965	COG1120	ATPase activity
C2H92_11980	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_11985	COG0783	Belongs to the Dps family
C2H92_11990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2H92_11995	COG0745	RESPONSE REGULATOR receiver
C2H92_12010	COG1309	transcriptional regulator
C2H92_12015	COG0114	fumarate hydratase activity
C2H92_12025	COG0697	spore germination
C2H92_12040	COG2197	response regulator
C2H92_12045	COG4585	Histidine kinase
C2H92_12050	COG4758	membrane
C2H92_12055	COG3595	metallopeptidase activity
C2H92_12060	COG1842	Phage shock protein A
C2H92_12065	COG4758	membrane
C2H92_12070	COG2814	Major facilitator Superfamily
C2H92_12075	COG2096	Adenosyltransferase
C2H92_12080	COG1120	ATPase activity
C2H92_12085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_12090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2H92_12095	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_12105	COG2205	protein histidine kinase activity
C2H92_12110	COG0745	RESPONSE REGULATOR receiver
C2H92_12120	COG1191	sigma factor activity
C2H92_12130	COG2140	Oxalate decarboxylase
C2H92_12140	COG0577	efflux transmembrane transporter activity
C2H92_12145	COG1136	(ABC) transporter
C2H92_12150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2H92_12155	COG1120	ATPase activity
C2H92_12160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_12170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2H92_12180	COG0531	amino acid
C2H92_12195	COG1988	membrane-bound metal-dependent
C2H92_12205	COG1910	domain protein
C2H92_12210	COG0725	ABC transporter, periplasmic molybdate-binding protein
C2H92_12215	COG4149	molybdate abc transporter
C2H92_12220	COG0656	L-ascorbic acid biosynthetic process
C2H92_12230	COG0025	NhaP-type Na H and K H
C2H92_12235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2H92_12240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C2H92_12245	COG3973	AAA domain
C2H92_12260	COG2860	membrane
C2H92_12265	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C2H92_12270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2H92_12275	COG2217	Heavy metal translocating P-type atpase
C2H92_12280	COG2217	Heavy metal translocating P-type atpase
C2H92_12285	COG2608	mercury ion transmembrane transporter activity
C2H92_12290	COG1937	Protein conserved in bacteria
C2H92_12295	COG0673	inositol 2-dehydrogenase activity
C2H92_12300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C2H92_12305	COG1289	transmembrane transporter activity
C2H92_12310	COG1802	Transcriptional regulator
C2H92_12315	COG0697	spore germination
C2H92_12325	COG2076	Multidrug Resistance protein
C2H92_12330	COG1309	transcriptional regulator
C2H92_12335	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_12355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C2H92_12360	COG0557	exoribonuclease II activity
C2H92_12365	COG1647	Serine aminopeptidase, S33
C2H92_12370	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C2H92_12375	COG0596	Alpha beta hydrolase
C2H92_12380	COG1476	TRANSCRIPTIONal
C2H92_12385	COG1396	sequence-specific DNA binding
C2H92_12390	COG1396	sequence-specific DNA binding
C2H92_12395	COG1733	regulation of RNA biosynthetic process
C2H92_12400	COG0840	transmembrane signaling receptor activity
C2H92_12405	COG1174	glycine betaine transport
C2H92_12410	COG1732	Glycine betaine
C2H92_12415	COG1174	glycine betaine transport
C2H92_12425	COG1510	regulation of RNA biosynthetic process
C2H92_12430	COG1174	glycine betaine transport
C2H92_12435	COG1732	Glycine betaine
C2H92_12440	COG1174	glycine betaine transport
C2H92_12445	COG1125	glycine betaine transport
C2H92_12445	COG0517	IMP dehydrogenase activity
C2H92_12450	COG1510	regulation of RNA biosynthetic process
C2H92_12460	COG3064	Membrane
C2H92_12465	COG4640	response to antibiotic
C2H92_12470	COG0456	acetyltransferase
C2H92_12480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C2H92_12485	COG0149	triose-phosphate isomerase activity
C2H92_12490	COG0126	phosphoglycerate kinase activity
C2H92_12495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C2H92_12500	COG2390	Transcriptional regulator
C2H92_12505	COG2814	Major facilitator Superfamily
C2H92_12510	COG1609	Transcriptional regulator
C2H92_12515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2H92_12520	COG0583	DNA-binding transcription factor activity
C2H92_12525	COG0697	spore germination
C2H92_12530	COG1113	amino acid transport
C2H92_12535	COG3858	chitin binding
C2H92_12540	COG1556	Lactate utilization protein
C2H92_12545	COG1139	Iron-sulfur cluster binding protein
C2H92_12550	COG0247	lactate metabolic process
C2H92_12565	COG2197	response regulator
C2H92_12570	COG4585	Histidine kinase
C2H92_12575	COG0842	Transport permease protein
C2H92_12580	COG1131	(ABC) transporter
C2H92_12585	COG0596	Alpha beta hydrolase
C2H92_12590	COG2208	phosphoserine phosphatase activity
C2H92_12595	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C2H92_12600	COG1874	Beta-galactosidase
C2H92_12605	COG3833	ABC-type maltose transport systems, permease component
C2H92_12610	COG1175	transmembrane transport
C2H92_12615	COG2182	Extracellular solute-binding protein
C2H92_12620	COG1609	Transcriptional regulator
C2H92_12630	COG1620	l-lactate permease
C2H92_12635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C2H92_12645	COG5039	Polysaccharide pyruvyl transferase
C2H92_12650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C2H92_12655	COG0110	maltose O-acetyltransferase activity
C2H92_12660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C2H92_12665	COG2244	polysaccharide biosynthetic process
C2H92_12670	COG1216	Glycosyl transferase, family 2
C2H92_12675	COG5039	Polysaccharide pyruvyl transferase
C2H92_12680	COG1216	Glycosyl transferase, family 2
C2H92_12690	COG0438	transferase activity, transferring glycosyl groups
C2H92_12695	COG1215	transferase activity, transferring glycosyl groups
C2H92_12700	COG0438	transferase activity, transferring glycosyl groups
C2H92_12705	COG1086	Polysaccharide biosynthesis protein
C2H92_12710	COG0489	protein tyrosine kinase activity
C2H92_12715	COG3944	biosynthesis protein
C2H92_12720	COG1396	sequence-specific DNA binding
C2H92_12750	COG3479	Phenolic acid decarboxylase
C2H92_12760	COG1794	racemase activity, acting on amino acids and derivatives
C2H92_12765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2H92_12775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C2H92_12780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2H92_12785	COG0640	Transcriptional regulator
C2H92_12790	COG1621	beta-fructofuranosidase activity
C2H92_12795	COG1621	beta-fructofuranosidase activity
C2H92_12800	COG0531	amino acid
C2H92_12805	COG1309	transcriptional regulator
C2H92_12810	COG2076	Multidrug Resistance protein
C2H92_12815	COG2076	Multidrug Resistance protein
C2H92_12835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2H92_12840	COG0366	Alpha amylase catalytic
C2H92_12850	COG5521	maltodextrose utilization protein MalA
C2H92_12855	COG3833	ABC-type maltose transport systems, permease component
C2H92_12860	COG1175	transmembrane transport
C2H92_12865	COG2182	Extracellular solute-binding protein
C2H92_12875	COG1609	Transcriptional regulator
C2H92_12880	COG1611	Belongs to the LOG family
C2H92_12885	COG1694	Mazg nucleotide pyrophosphohydrolase
C2H92_12890	COG0659	secondary active sulfate transmembrane transporter activity
C2H92_12895	COG0288	reversible hydration of carbon dioxide
C2H92_12900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2H92_12905	COG0577	efflux transmembrane transporter activity
C2H92_12910	COG1136	(ABC) transporter
C2H92_12915	COG5002	protein histidine kinase activity
C2H92_12920	COG0745	RESPONSE REGULATOR receiver
C2H92_12930	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C2H92_12935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H92_12940	COG1481	regulation of sporulation
C2H92_12945	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C2H92_12950	COG1660	Displays ATPase and GTPase activities
C2H92_12955	COG1051	belongs to the nudix hydrolase family
C2H92_12960	COG0492	ferredoxin-NADP+ reductase activity
C2H92_12965	COG0791	NLP P60 protein
C2H92_12965	COG3883	PFAM NLP P60 protein
C2H92_12970	COG0457	Tetratricopeptide repeat
C2H92_12975	COG1132	(ABC) transporter
C2H92_13005	COG0140	phosphoribosyl-ATP diphosphatase activity
C2H92_13005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C2H92_13010	COG0107	imidazoleglycerol-phosphate synthase activity
C2H92_13020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C2H92_13025	COG0131	Imidazoleglycerol-phosphate dehydratase
C2H92_13030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C2H92_13035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C2H92_13040	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C2H92_13045	COG4990	cell redox homeostasis
C2H92_13050	COG5297	Belongs to the glycosyl hydrolase family 6
C2H92_13055	COG0110	maltose O-acetyltransferase activity
C2H92_13060	COG0546	phosphoglycolate phosphatase activity
C2H92_13065	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C2H92_13070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C2H92_13075	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C2H92_13080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2H92_13085	COG0363	glucosamine-6-phosphate deaminase activity
C2H92_13090	COG2188	Transcriptional regulator
C2H92_13095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C2H92_13100	COG1846	Transcriptional regulator
C2H92_13105	COG2814	Major facilitator Superfamily
C2H92_13110	COG1950	PFAM Membrane protein of
C2H92_13115	COG1983	PspC domain protein
C2H92_13120	COG3595	metallopeptidase activity
C2H92_13135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C2H92_13145	COG4897	Protein conserved in bacteria
C2H92_13150	COG0574	Belongs to the PEP-utilizing enzyme family
C2H92_13150	COG3848	Pyruvate phosphate dikinase
C2H92_13155	COG1309	transcriptional regulator
C2H92_13160	COG2814	Major facilitator Superfamily
C2H92_13165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2H92_13175	COG0793	Belongs to the peptidase S41A family
C2H92_13175	COG3409	Peptidoglycan-binding domain 1 protein
C2H92_13180	COG2177	Part of the ABC transporter FtsEX involved in
C2H92_13185	COG2884	Cell division ATP-binding protein ftsE
C2H92_13190	COG2010	Cytochrome c
C2H92_13195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2H92_13205	COG0653	protein targeting
C2H92_13210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C2H92_13225	COG1516	flagellar protein fliS
C2H92_13230	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C2H92_13235	COG1334	flagellar protein FlaG
C2H92_13240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C2H92_13245	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C2H92_13260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C2H92_13265	COG4786	Flagellar basal body rod
C2H92_13265	COG1256	bacterial-type flagellum assembly
C2H92_13270	COG3418	PFAM FlgN family protein
C2H92_13275	COG2747	anti-sigma28 factor FlgM
C2H92_13285	COG1040	competence protein
C2H92_13295	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C2H92_13300	COG1307	EDD domain protein, DegV family
C2H92_13305	COG2197	response regulator
C2H92_13310	COG4585	Histidine kinase
C2H92_13315	COG1739	Uncharacterized protein family UPF0029
C2H92_13320	COG1316	TRANSCRIPTIONal
C2H92_13325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C2H92_13330	COG0438	transferase activity, transferring glycosyl groups
C2H92_13335	COG1215	transferase activity, transferring glycosyl groups
C2H92_13340	COG3206	protein involved in exopolysaccharide biosynthesis
C2H92_13345	COG3307	-O-antigen
C2H92_13350	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C2H92_13355	COG0438	transferase activity, transferring glycosyl groups
C2H92_13355	COG0297	glycogen (starch) synthase activity
C2H92_13360	COG2244	polysaccharide biosynthetic process
C2H92_13370	COG2247	cell wall binding repeat
C2H92_13370	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H92_13375	COG2385	sporulation resulting in formation of a cellular spore
C2H92_13375	COG2247	cell wall binding repeat
C2H92_13385	COG1316	TRANSCRIPTIONal
C2H92_13390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C2H92_13395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C2H92_13405	COG1682	transport, permease protein
C2H92_13410	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C2H92_13420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C2H92_13425	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C2H92_13430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C2H92_13440	COG4193	domain, Protein
C2H92_13450	COG0697	spore germination
C2H92_13455	COG0814	amino acid
C2H92_13465	COG2814	Major facilitator Superfamily
C2H92_13470	COG1316	TRANSCRIPTIONal
C2H92_13475	COG0561	phosphatase activity
C2H92_13480	COG0791	NLP P60 protein
C2H92_13490	COG2843	Capsule synthesis protein
C2H92_13500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C2H92_13505	COG1609	Transcriptional regulator
C2H92_13510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H92_13515	COG1869	D-ribose catabolic process
C2H92_13520	COG1129	ABC transporter
C2H92_13525	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2H92_13530	COG1879	ABC-type sugar transport system periplasmic component
C2H92_13535	COG3103	Sh3 type 3 domain protein
C2H92_13545	COG2249	NAD(P)H dehydrogenase (quinone) activity
C2H92_13550	COG3527	Alpha-acetolactate decarboxylase
C2H92_13555	COG0028	Belongs to the TPP enzyme family
C2H92_13560	COG0583	DNA-binding transcription factor activity
C2H92_13565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2H92_13580	COG5337	Spore coat protein CotH
C2H92_13590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2H92_13610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2H92_13620	COG0405	Gamma-glutamyltransferase
C2H92_13625	COG1522	sequence-specific DNA binding
C2H92_13630	COG2059	Chromate
C2H92_13635	COG2059	Chromate
C2H92_13645	COG0655	NAD(P)H dehydrogenase (quinone) activity
C2H92_13650	COG0583	DNA-binding transcription factor activity
C2H92_13750	COG5444	nuclease activity
C2H92_13770	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C2H92_13775	COG4464	protein tyrosine phosphatase activity
C2H92_13780	COG0489	protein tyrosine kinase activity
C2H92_13785	COG3944	biosynthesis protein
C2H92_13805	COG0561	phosphatase activity
C2H92_13810	COG1349	DNA-binding transcription factor activity
C2H92_13815	COG0629	single-stranded DNA binding
C2H92_13830	COG2602	Beta-lactamase
C2H92_13840	COG3764	Sortase (surface protein transpeptidase)
C2H92_13850	COG3279	Response regulator of the LytR AlgR family
C2H92_13855	COG0745	RESPONSE REGULATOR receiver
C2H92_13855	COG2972	Histidine kinase
C2H92_13860	COG1970	mechanosensitive ion channel activity
C2H92_13865	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C2H92_13870	COG0457	Tetratricopeptide repeat
C2H92_13875	COG4786	Flagellar basal body rod
C2H92_13880	COG4786	Flagellar basal body rod
C2H92_13885	COG1077	Cell shape determining protein MreB Mrl
C2H92_13890	COG1609	Transcriptional regulator
C2H92_13900	COG1846	Transcriptional regulator
C2H92_13905	COG2814	Major facilitator Superfamily
C2H92_13910	COG3420	alginic acid biosynthetic process
C2H92_13915	COG1953	Uracil, thiamine, allantoin
C2H92_13920	COG0477	Major facilitator Superfamily
C2H92_13925	COG1335	isochorismatase
C2H92_13935	COG0004	ammonium transporteR
C2H92_13940	COG0347	Belongs to the P(II) protein family
C2H92_13945	COG0671	phosphoesterase, PA-phosphatase related
C2H92_13955	COG0739	heme binding
C2H92_13960	COG1247	-acetyltransferase
C2H92_13975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2H92_13985	COG2910	NAD(P)H-binding
C2H92_13990	COG1959	2 iron, 2 sulfur cluster binding
C2H92_13995	COG0804	urea catabolic process
C2H92_14000	COG0832	Belongs to the urease beta subunit family
C2H92_14005	COG0831	urea catabolic process
C2H92_14035	COG3237	CsbD-like
C2H92_14040	COG1994	Peptidase M50
C2H92_14045	COG0457	Tetratricopeptide repeat
C2H92_14050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C2H92_14055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C2H92_14065	COG2304	oxidoreductase activity
C2H92_14075	COG2304	oxidoreductase activity
C2H92_14085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C2H92_14095	COG4836	Membrane
C2H92_14105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C2H92_14110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C2H92_14115	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C2H92_14125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C2H92_14130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C2H92_14140	COG0356	it plays a direct role in the translocation of protons across the membrane
C2H92_14155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C2H92_14160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C2H92_14165	COG4475	Protein of unknown function (DUF436)
C2H92_14170	COG0698	ribose 5-phosphate isomerase
C2H92_14175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C2H92_14180	COG1971	Probably functions as a manganese efflux pump
C2H92_14185	COG0009	L-threonylcarbamoyladenylate synthase
C2H92_14190	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C2H92_14210	COG2890	protein-(glutamine-N5) methyltransferase activity
C2H92_14215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C2H92_14220	COG0346	lactoylglutathione lyase activity
C2H92_14225	COG0789	Transcriptional regulator
C2H92_14230	COG0679	Auxin Efflux Carrier
C2H92_14235	COG0281	malic enzyme
C2H92_14240	COG1435	thymidine kinase activity
C2H92_14250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C2H92_14255	COG1494	fructose-1,6-bisphosphatase
C2H92_14265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2H92_14270	COG0191	fructose-bisphosphate aldolase activity
C2H92_14275	COG2204	response regulator
C2H92_14280	COG4821	SIS domain
C2H92_14285	COG0504	CTP synthase activity
C2H92_14290	COG3343	RNA polymerase activity
C2H92_14295	COG1960	acyl-CoA dehydrogenase activity
C2H92_14300	COG0247	lactate metabolic process
C2H92_14300	COG2181	nitrate reductase activity
C2H92_14305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2H92_14310	COG4294	response to UV
C2H92_14320	COG1476	TRANSCRIPTIONal
C2H92_14335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2H92_14345	COG2181	nitrate reductase activity
C2H92_14350	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C2H92_14355	COG1140	nitrate reductase beta subunit
C2H92_14360	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C2H92_14365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2H92_14375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2H92_14380	COG2223	nitrite transmembrane transporter activity
C2H92_14385	COG0018	arginyl-trna synthetase
C2H92_14390	COG4506	Protein conserved in bacteria
C2H92_14405	COG0535	radical SAM domain protein
C2H92_14415	COG1131	(ABC) transporter
C2H92_14425	COG0612	Peptidase, M16
C2H92_14445	COG3391	amine dehydrogenase activity
C2H92_14455	COG0457	Tetratricopeptide repeat
C2H92_14465	COG0010	Belongs to the arginase family
C2H92_14470	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C2H92_14475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2H92_14555	COG1994	Peptidase M50
C2H92_14560	COG1942	4-Oxalocrotonate Tautomerase
C2H92_14565	COG1846	Transcriptional regulator
C2H92_14570	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C2H92_14575	COG0477	Major facilitator Superfamily
C2H92_14580	COG1959	2 iron, 2 sulfur cluster binding
C2H92_14585	COG3465	dGTPase activity
C2H92_14590	COG1078	dGTPase activity
C2H92_14595	COG4844	belongs to the
C2H92_14605	COG0697	spore germination
C2H92_14615	COG0583	DNA-binding transcription factor activity
C2H92_14620	COG0280	phosphate acetyltransferase
C2H92_14625	COG3253	May function as heme-dependent peroxidase
C2H92_14630	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_14635	COG0436	Aminotransferase
C2H92_14640	COG2814	Major facilitator Superfamily
C2H92_14645	COG0151	Belongs to the GarS family
C2H92_14650	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_14655	COG1917	Cupin 2, conserved barrel domain protein
C2H92_14660	COG0077	Prephenate dehydratase
C2H92_14665	COG2814	Major facilitator Superfamily
C2H92_14675	COG0833	amino acid
C2H92_14680	COG4187	Peptidase family M20/M25/M40
C2H92_14685	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_14690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2H92_14700	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C2H92_14705	COG1091	dTDP-4-dehydrorhamnose reductase activity
C2H92_14710	COG1088	dTDP-glucose 4,6-dehydratase activity
C2H92_14715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C2H92_14720	COG3980	spore coat polysaccharide biosynthesis protein
C2H92_14725	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C2H92_14730	COG2089	acid synthase
C2H92_14735	COG0456	acetyltransferase
C2H92_14740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C2H92_14745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C2H92_14750	COG0463	Glycosyl transferase, family 2
C2H92_14765	COG2363	Small membrane protein
C2H92_14770	COG2233	PERMEase
C2H92_14780	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_14785	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C2H92_14790	COG1216	Glycosyl transferase, family 2
C2H92_14805	COG1695	Transcriptional regulator
C2H92_14810	COG0351	phosphomethylpyrimidine kinase
C2H92_14820	COG1621	beta-fructofuranosidase activity
C2H92_14825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H92_14825	COG1263	PTS System
C2H92_14830	COG2116	formate transmembrane transporter activity
C2H92_14835	COG3711	transcriptional antiterminator
C2H92_14845	COG1404	Belongs to the peptidase S8 family
C2H92_14850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2H92_14855	COG0778	Nitroreductase
C2H92_14860	COG0772	Belongs to the SEDS family
C2H92_14885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C2H92_14890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C2H92_14895	COG2261	transglycosylase associated protein
C2H92_14900	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C2H92_14905	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C2H92_14910	COG2246	polysaccharide biosynthetic process
C2H92_14915	COG1309	transcriptional regulator
C2H92_14925	COG3162	membrane
C2H92_14930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2H92_14935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C2H92_14950	COG0352	thiamine-phosphate diphosphorylase activity
C2H92_14955	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C2H92_14960	COG0583	DNA-binding transcription factor activity
C2H92_14965	COG1380	Effector of murein hydrolase LrgA
C2H92_14970	COG1346	cytolysis
C2H92_14975	COG2814	Major facilitator Superfamily
C2H92_14980	COG4895	conserved protein (DUF2196)
C2H92_14985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C2H92_14990	COG0346	lactoylglutathione lyase activity
C2H92_15000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2H92_15010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H92_15010	COG1263	PTS System
C2H92_15015	COG3711	transcriptional antiterminator
C2H92_15020	COG1442	glycosyl transferase family 8
C2H92_15025	COG5522	Integral membrane protein (intg_mem_TP0381)
C2H92_15030	COG1846	Transcriptional regulator
C2H92_15035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C2H92_15040	COG2234	aminopeptidase activity
C2H92_15055	COG2814	Major facilitator Superfamily
C2H92_15060	COG2357	RelA SpoT domain protein
C2H92_15065	COG1575	Belongs to the MenA family. Type 1 subfamily
C2H92_15080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2H92_15085	COG1696	Membrane protein involved in D-alanine export
C2H92_15090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C2H92_15095	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C2H92_15100	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C2H92_15105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2H92_15110	COG1486	melibiose metabolic process
C2H92_15115	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2H92_15120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2H92_15125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2H92_15130	COG3711	transcriptional antiterminator
C2H92_15130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H92_15140	COG2094	Belongs to the DNA glycosylase MPG family
C2H92_15145	COG0753	catalase activity
C2H92_15150	COG2814	Major facilitator Superfamily
C2H92_15155	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C2H92_15160	COG1131	(ABC) transporter
C2H92_15180	COG1595	DNA-templated transcription, initiation
C2H92_15185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C2H92_15190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C2H92_15195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C2H92_15205	COG1294	oxidase, subunit
C2H92_15210	COG1271	oxidase subunit
C2H92_15215	COG3493	citrate carrier protein
C2H92_15220	COG0501	Belongs to the peptidase M48B family
C2H92_15230	COG0726	polysaccharide deacetylase
C2H92_15240	COG3842	ATPase activity
C2H92_15245	COG2508	Transcriptional regulator
C2H92_15250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2H92_15260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C2H92_15270	COG4585	Histidine kinase
C2H92_15275	COG2197	response regulator
C2H92_15280	COG2195	Cleaves the N-terminal amino acid of tripeptides
C2H92_15290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C2H92_15295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C2H92_15300	COG3290	protein histidine kinase activity
C2H92_15300	COG3829	transcription factor binding
C2H92_15305	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_15310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C2H92_15315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C2H92_15325	COG0500	methyltransferase
C2H92_15330	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_15335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2H92_15350	COG0753	catalase activity
C2H92_15350	COG0693	protein deglycase activity
C2H92_15355	COG2851	Citrate transporter
C2H92_15360	COG2323	membrane
C2H92_15380	COG2270	Major facilitator Superfamily
C2H92_15385	COG0513	Belongs to the DEAD box helicase family
C2H92_15390	COG3401	FG-GAP repeat protein
C2H92_15390	COG2755	lipolytic protein G-D-S-L family
C2H92_15485	COG0697	spore germination
C2H92_15490	COG0589	response to stress
C2H92_15550	COG0494	nUDIX hydrolase
C2H92_15560	COG3507	Belongs to the glycosyl hydrolase 43 family
C2H92_15570	COG2986	histidine ammonia-lyase
C2H92_15575	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C2H92_15580	COG1228	amidohydrolase
C2H92_15585	COG0010	Belongs to the arginase family
C2H92_15590	COG0833	amino acid
C2H92_15595	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C2H92_15600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2H92_15605	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C2H92_15610	COG2390	Transcriptional regulator
C2H92_15635	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C2H92_15640	COG0561	phosphatase activity
C2H92_15670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2H92_15675	COG5294	Protein conserved in bacteria
C2H92_15680	COG0577	efflux transmembrane transporter activity
C2H92_15685	COG1136	(ABC) transporter
C2H92_15690	COG2205	protein histidine kinase activity
C2H92_15695	COG0745	RESPONSE REGULATOR receiver
C2H92_15700	COG0191	fructose-bisphosphate aldolase activity
C2H92_15705	COG1082	Xylose isomerase domain protein TIM barrel
C2H92_15710	COG1082	Xylose isomerase domain protein TIM barrel
C2H92_15715	COG0673	inositol 2-dehydrogenase activity
C2H92_15720	COG2814	Major facilitator Superfamily
C2H92_15725	COG1082	Xylose isomerase domain protein TIM barrel
C2H92_15730	COG3962	Belongs to the TPP enzyme family
C2H92_15735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H92_15745	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_15750	COG1349	DNA-binding transcription factor activity
C2H92_15755	COG0667	Aldo Keto reductase
C2H92_15780	COG2814	Major facilitator Superfamily
C2H92_15785	COG0326	Molecular chaperone. Has ATPase activity
C2H92_15795	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_15810	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_15815	COG1714	RDD family
C2H92_15820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2H92_15830	COG1714	RDD family
C2H92_15835	COG2311	Membrane
C2H92_15870	COG5039	Polysaccharide pyruvyl transferase
C2H92_15875	COG1929	Belongs to the glycerate kinase type-1 family
C2H92_15880	COG1802	Transcriptional regulator
C2H92_15885	COG1070	Carbohydrate kinase
C2H92_15890	COG2610	gluconate transmembrane transporter activity
C2H92_15895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C2H92_15900	COG0450	alkyl hydroperoxide reductase
C2H92_15905	COG3634	alkyl hydroperoxide reductase activity
C2H92_15920	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C2H92_15950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C2H92_15965	COG1063	alcohol dehydrogenase
C2H92_15980	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C2H92_15985	COG0456	acetyltransferase
C2H92_15990	COG0457	Tetratricopeptide repeat
C2H92_16000	COG0010	Belongs to the arginase family
C2H92_16005	COG0833	amino acid
C2H92_16010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C2H92_16015	COG3829	transcription factor binding
C2H92_16025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2H92_16030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C2H92_16035	COG4853	Protein conserved in bacteria
C2H92_16040	COG4863	YycH protein
C2H92_16045	COG5002	protein histidine kinase activity
C2H92_16050	COG0745	RESPONSE REGULATOR receiver
C2H92_16080	COG0346	lactoylglutathione lyase activity
C2H92_16085	COG0305	Participates in initiation and elongation during chromosome replication
C2H92_16100	COG3093	addiction module antidote protein HigA
C2H92_16105	COG2807	transmembrane transport
C2H92_16110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C2H92_16115	COG0359	binds to the 23S rRNA
C2H92_16120	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C2H92_16125	COG4241	membrane
C2H92_16135	COG5577	PFAM Coat F domain
C2H92_16140	COG1733	regulation of RNA biosynthetic process
C2H92_16145	COG1227	inorganic diphosphatase activity
C2H92_16160	COG2271	Major facilitator Superfamily
C2H92_16165	COG4978	Transcriptional regulator
C2H92_16165	COG0789	Transcriptional regulator
C2H92_16180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2H92_16190	COG0640	Transcriptional regulator
C2H92_16195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2H92_16215	COG2197	response regulator
C2H92_16235	COG0789	Transcriptional regulator
C2H92_16235	COG4978	Transcriptional regulator
C2H92_16240	COG1811	Na channel or pump
C2H92_16260	COG0789	Transcriptional regulator
C2H92_16270	COG1331	Highly conserved protein containing a thioredoxin domain
C2H92_16280	COG1522	sequence-specific DNA binding
C2H92_16295	COG0789	Transcriptional regulator
C2H92_16310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2H92_16320	COG1331	Highly conserved protein containing a thioredoxin domain
C2H92_16345	COG5002	protein histidine kinase activity
C2H92_16350	COG0745	RESPONSE REGULATOR receiver
C2H92_16360	COG1331	Highly conserved protein containing a thioredoxin domain
C2H92_16400	COG0741	lytic transglycosylase activity
C2H92_16400	COG0791	NLP P60 protein
C2H92_16405	COG5644	endopeptidase inhibitor activity
C2H92_16450	COG2946	Replication initiation factor
C2H92_16455	COG1674	ftsk spoiiie
C2H92_16480	COG1396	sequence-specific DNA binding
C2H92_16485	COG2856	Zn peptidase
C2H92_16490	COG0457	Tetratricopeptide repeat
C2H92_16510	COG1331	Highly conserved protein containing a thioredoxin domain
C2H92_16515	COG1331	Highly conserved protein containing a thioredoxin domain
C2H92_16520	COG1266	CAAX protease self-immunity
C2H92_16525	COG0477	Major facilitator Superfamily
C2H92_16525	COG2814	Major facilitator Superfamily
C2H92_16530	COG0110	maltose O-acetyltransferase activity
C2H92_16535	COG0346	lactoylglutathione lyase activity
C2H92_16545	COG0708	Exodeoxyribonuclease III
C2H92_16555	COG0629	single-stranded DNA binding
C2H92_16570	COG0243	molybdopterin cofactor binding
C2H92_16580	COG3949	Membrane
C2H92_16595	COG1475	DNA binding
C2H92_16600	COG1192	Involved in chromosome partitioning
C2H92_16610	COG1475	DNA binding
C2H92_16615	COG0357	Ribosomal RNA small subunit methyltransferase G
C2H92_16620	COG0445	tRNA wobble uridine modification
C2H92_16625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C2H92_16630	COG1847	R3H domain protein
C2H92_16635	COG0706	membrane insertase activity
C2H92_16640	COG0594	ribonuclease P activity
C2H92_16650	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C2H92_16655	COG0592	DNA-directed DNA polymerase activity
C2H92_16660	COG2501	S4 domain
C2H92_16665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C2H92_16675	COG0187	DNA topoisomerase II activity
C2H92_16680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C2H92_16720	COG1686	Belongs to the peptidase S11 family
C2H92_16730	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C2H92_16735	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C2H92_16745	COG1428	Deoxynucleoside kinase
C2H92_16750	COG1428	Deoxynucleoside kinase
C2H92_16755	COG1388	LysM domain
C2H92_16755	COG3858	chitin binding
C2H92_16760	COG1335	isochorismatase
C2H92_16765	COG0590	tRNA wobble adenosine to inosine editing
C2H92_16775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C2H92_16780	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C2H92_16785	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C2H92_16830	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C2H92_16835	COG3853	Toxic anion resistance protein (TelA)
C2H92_16840	COG1982	Orn Lys Arg decarboxylase major
C2H92_16845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C2H92_16850	COG3870	Protein conserved in bacteria
C2H92_16855	COG1728	Protein conserved in bacteria
C2H92_16860	COG0470	DNA polymerase III
C2H92_16865	COG1774	PSP1 C-terminal conserved region
C2H92_16875	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C2H92_16880	COG2827	Endonuclease containing a URI domain
C2H92_16885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C2H92_16890	COG2002	toxin-antitoxin pair type II binding
C2H92_16895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2H92_16895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2H92_16900	COG0084	hydrolase, TatD family'
C2H92_16905	COG3584	3D domain protein
C2H92_16905	COG3583	domain protein
C2H92_16910	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C2H92_16915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C2H92_16925	COG4466	Protein conserved in bacteria
C2H92_16935	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C2H92_16945	COG0251	oxidation-reduction process
C2H92_16950	COG2088	sporulation resulting in formation of a cellular spore
C2H92_16955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C2H92_16960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C2H92_16965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C2H92_16970	COG0193	aminoacyl-tRNA hydrolase activity
C2H92_16980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C2H92_16985	COG2002	toxin-antitoxin pair type II binding
C2H92_16990	COG2244	polysaccharide biosynthetic process
C2H92_16995	COG3956	TIGRFAM MazG family protein
C2H92_17000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C2H92_17015	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C2H92_17020	COG1098	S1 RNA binding domain
C2H92_17035	COG2208	phosphoserine phosphatase activity
C2H92_17045	COG0515	serine threonine protein kinase
C2H92_17050	COG0037	tRNA processing
C2H92_17055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C2H92_17060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C2H92_17065	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C2H92_17070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C2H92_17075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2H92_17080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2H92_17085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C2H92_17090	COG0512	Glutamine amidotransferase of anthranilate synthase
C2H92_17095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2H92_17100	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C2H92_17105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C2H92_17110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2H92_17115	COG1396	sequence-specific DNA binding
C2H92_17120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2H92_17125	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C2H92_17205	COG4463	regulation of RNA biosynthetic process
C2H92_17210	COG3880	PFAM UvrB UvrC protein
C2H92_17215	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C2H92_17220	COG0542	response to heat
C2H92_17225	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C2H92_17230	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C2H92_17235	COG4956	integral membrane protein (PIN domain superfamily)
C2H92_17240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C2H92_17245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C2H92_17250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C2H92_17255	COG1045	serine acetyltransferase
C2H92_17260	COG0215	cysteine-tRNA ligase activity
C2H92_17265	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C2H92_17270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2H92_17275	COG3688	RNA-binding protein containing a PIN domain
C2H92_17280	COG1595	DNA-templated transcription, initiation
C2H92_17290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C2H92_17295	COG0250	Participates in transcription elongation, termination and antitermination
C2H92_17305	COG0081	regulation of translation
C2H92_17320	COG2813	Specifically methylates the guanine in position
C2H92_17325	COG0085	RNA polymerase activity
C2H92_17330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C2H92_17335	COG1358	cellular component organization or biogenesis
C2H92_17345	COG0049	tRNA binding
C2H92_17355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C2H92_17360	COG0596	Alpha beta hydrolase
C2H92_17370	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C2H92_17385	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C2H92_17405	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C2H92_17415	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C2H92_17420	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C2H92_17430	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C2H92_17440	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C2H92_17445	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C2H92_17450	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C2H92_17465	COG0200	Binds to the 23S rRNA
C2H92_17470	COG0201	protein transport
C2H92_17475	COG0563	adenylate kinase activity
C2H92_17480	COG0024	Methionine aminopeptidase
C2H92_17495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C2H92_17505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C2H92_17510	COG0202	RNA polymerase activity
C2H92_17515	COG0203	ribosomal protein L17
C2H92_17520	COG1122	ATPase activity
C2H92_17530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C2H92_17535	COG0101	tRNA pseudouridine synthase activity
C2H92_17540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C2H92_17550	COG2226	methyltransferase
C2H92_17560	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2H92_17565	COG0489	protein tyrosine kinase activity
C2H92_17575	COG2194	sulfuric ester hydrolase activity
C2H92_17580	COG0726	polysaccharide deacetylase
C2H92_17665	COG0659	secondary active sulfate transmembrane transporter activity
C2H92_17670	COG0385	Bile acid
C2H92_17675	COG2819	hydrolase of the alpha beta superfamily
C2H92_17680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_17685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_17690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2H92_17695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2H92_17695	COG2207	Transcriptional regulator
C2H92_17700	COG3876	Protein conserved in bacteria
C2H92_17710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2H92_17720	COG1737	Transcriptional regulator
C2H92_17725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C2H92_17730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_17735	COG1683	Conserved Protein
C2H92_17765	COG1595	DNA-templated transcription, initiation
C2H92_17770	COG5662	AntiSigma factor
C2H92_17780	COG4856	YbbR-like protein
C2H92_17785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C2H92_17800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C2H92_17805	COG2169	Transcriptional regulator
C2H92_17815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C2H92_17820	COG3002	Belongs to the UPF0753 family
C2H92_17825	COG0288	reversible hydration of carbon dioxide
C2H92_17835	COG5609	conserved protein (DUF2294)
C2H92_17840	COG0640	Transcriptional regulator
C2H92_17845	COG2814	Major facilitator Superfamily
C2H92_17855	COG1413	lyase activity
C2H92_17870	COG0596	Alpha beta hydrolase
C2H92_17875	COG0745	RESPONSE REGULATOR receiver
C2H92_17880	COG0642	Histidine kinase
C2H92_17890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C2H92_17900	COG2211	Major facilitator Superfamily
C2H92_17910	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
C2H92_17910	COG0028	Belongs to the TPP enzyme family
C2H92_17955	COG1113	amino acid transport
C2H92_17970	COG2602	Beta-lactamase
C2H92_17975	COG2124	cytochrome p450
C2H92_17985	COG0531	amino acid
C2H92_17995	COG0584	glycerophosphoryl diester phosphodiesterase
C2H92_18000	COG2271	Major facilitator Superfamily
C2H92_18015	COG1846	Transcriptional regulator
C2H92_18015	COG0456	acetyltransferase
C2H92_18020	COG2271	Major facilitator Superfamily
C2H92_18030	COG3409	Peptidoglycan-binding domain 1 protein
C2H92_18040	COG2207	Transcriptional regulator
C2H92_18040	COG1917	Cupin 2, conserved barrel domain protein
C2H92_18045	COG0371	Dehydrogenase
C2H92_18050	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C2H92_18055	COG3591	Belongs to the peptidase S1B family
C2H92_18065	COG0596	Alpha beta hydrolase
C2H92_18070	COG1183	phosphatidylcholine synthase activity
C2H92_18075	COG0586	Pfam SNARE associated Golgi protein
C2H92_18080	COG0688	phosphatidylethanolamine metabolic process
C2H92_18090	COG2312	Erythromycin esterase
C2H92_18095	COG2207	Transcriptional regulator
C2H92_18100	COG1054	Belongs to the UPF0176 family
C2H92_18105	COG1301	dicarboxylic acid transport
C2H92_18110	COG1263	PTS System
C2H92_18110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H92_18110	COG2190	(PTS) system
C2H92_18115	COG0363	glucosamine-6-phosphate deaminase activity
C2H92_18120	COG2188	Transcriptional regulator
C2H92_18130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2H92_18135	COG0833	amino acid
C2H92_18140	COG2040	homocysteine
C2H92_18145	COG1115	amino acid carrier protein
C2H92_18150	COG2066	Belongs to the glutaminase family
C2H92_18160	COG0784	Response regulator, receiver
C2H92_18165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2H92_18175	COG2271	Major facilitator Superfamily
C2H92_18180	COG4948	Mandelate Racemase Muconate Lactonizing
C2H92_18185	COG2186	Transcriptional regulator
C2H92_18190	COG2721	sulfolactate sulfo-lyase activity
C2H92_18195	COG3173	Aminoglycoside phosphotransferase
C2H92_18205	COG0697	spore germination
C2H92_18210	COG0745	RESPONSE REGULATOR receiver
C2H92_18215	COG2205	protein histidine kinase activity
C2H92_18220	COG1131	(ABC) transporter
C2H92_18245	COG3773	Cell wall hydrolase
C2H92_18250	COG2304	oxidoreductase activity
C2H92_18255	COG3540	Alkaline phosphatase
C2H92_18260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C2H92_18265	COG0805	protein transport
C2H92_18270	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C2H92_18275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C2H92_18280	COG0477	Major facilitator Superfamily
C2H92_18285	COG1309	transcriptional regulator
C2H92_18290	COG0252	asparaginase activity
C2H92_18295	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C2H92_18305	COG1405	negative regulation of cell septum assembly
C2H92_18305	COG3012	SEC-C Motif Domain Protein
C2H92_18310	COG3290	protein histidine kinase activity
C2H92_18320	COG4555	ABC transporter
C2H92_18325	COG1668	transmembrane transport
C2H92_18330	COG0667	Aldo Keto reductase
C2H92_18355	COG1876	peptidase activity
C2H92_18360	COG0457	Tetratricopeptide repeat
C2H92_18365	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_18375	COG0803	Belongs to the bacterial solute-binding protein 9 family
C2H92_18380	COG1121	(ABC) transporter
C2H92_18385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2H92_18390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2H92_18395	COG2310	stress, protein
C2H92_18400	COG2310	stress, protein
C2H92_18405	COG2310	stress, protein
C2H92_18410	COG0861	Integral membrane protein TerC family
C2H92_18425	COG1358	cellular component organization or biogenesis
C2H92_18440	COG3853	Toxic anion resistance protein (TelA)
C2H92_18445	COG0477	Major facilitator Superfamily
C2H92_18450	COG2814	Major facilitator Superfamily
C2H92_18455	COG0640	Transcriptional regulator
C2H92_18465	COG4176	ABC-type proline glycine betaine transport system permease component
C2H92_18470	COG2113	Glycine betaine
C2H92_18475	COG1473	amidohydrolase
C2H92_18480	COG1288	antiporter activity
C2H92_18490	COG0366	Alpha amylase catalytic
C2H92_18495	COG0039	L-malate dehydrogenase activity
C2H92_18500	COG1620	l-lactate permease
C2H92_18505	COG2814	Major facilitator Superfamily
C2H92_18510	COG1846	Transcriptional regulator
C2H92_18515	COG1280	lysine exporter protein (LysE YggA)
C2H92_18520	COG3403	YqcI/YcgG family
C2H92_18525	COG1113	amino acid transport
C2H92_18530	COG3665	Urea carboxylase-associated protein
C2H92_18535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C2H92_18540	COG1660	Displays ATPase and GTPase activities
C2H92_18555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C2H92_18565	COG3458	cephalosporin-C deacetylase activity
C2H92_18570	COG3541	Predicted nucleotidyltransferase
C2H92_18575	COG0506	proline dehydrogenase activity
C2H92_18580	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_18585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2H92_18590	COG2508	Transcriptional regulator
C2H92_18595	COG3689	TIGRFAM TIGR03943 family protein
C2H92_18600	COG0701	Predicted permease
C2H92_18605	COG2267	carboxylic ester hydrolase activity
C2H92_18610	COG0492	ferredoxin-NADP+ reductase activity
C2H92_18615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C2H92_18615	COG1587	Uroporphyrinogen-III synthase
C2H92_18620	COG2146	nitrite reductase [NAD(P)H] activity
C2H92_18625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2H92_18635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2H92_18640	COG2223	nitrite transmembrane transporter activity
C2H92_18645	COG1469	GTP cyclohydrolase I activity
C2H92_18660	COG0523	cobalamin synthesis protein
C2H92_18665	COG0765	amino acid transport
C2H92_18670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H92_18675	COG1063	alcohol dehydrogenase
C2H92_18680	COG1714	RDD family
C2H92_18690	COG1846	Transcriptional regulator
C2H92_18700	COG3842	ATPase activity
C2H92_18705	COG2723	6-phospho-beta-galactosidase activity
C2H92_18715	COG3209	COG3209 Rhs family protein
C2H92_18720	COG3290	protein histidine kinase activity
C2H92_18720	COG0840	transmembrane signaling receptor activity
C2H92_18725	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C2H92_18730	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C2H92_18735	COG1733	regulation of RNA biosynthetic process
C2H92_18740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2H92_18750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2H92_18760	COG2814	Major facilitator Superfamily
C2H92_18770	COG0697	spore germination
C2H92_18775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2H92_18790	COG0701	Predicted permease
C2H92_18795	COG2364	Membrane
C2H92_18800	COG1126	abc transporter atp-binding protein
C2H92_18805	COG0765	amino acid transport
C2H92_18810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2H92_18815	COG0583	DNA-binding transcription factor activity
C2H92_18820	COG0163	prenyltransferase activity
C2H92_18825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C2H92_18840	COG0596	Alpha beta hydrolase
C2H92_18845	COG3104	oligopeptide transport
C2H92_18850	COG5434	Belongs to the glycosyl hydrolase 28 family
C2H92_18860	COG0697	spore germination
C2H92_18870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C2H92_18875	COG1136	(ABC) transporter
C2H92_18880	COG0577	efflux transmembrane transporter activity
C2H92_18890	COG0745	RESPONSE REGULATOR receiver
C2H92_18900	COG0457	Tetratricopeptide repeat
C2H92_18920	COG0527	aspartate kinase activity
C2H92_18925	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_18930	COG4605	iron ion homeostasis
C2H92_18935	COG4604	ABC transporter, ATP-binding protein
C2H92_18940	COG4607	ABC-type enterochelin transport system periplasmic component
C2H92_18945	COG2814	Major facilitator Superfamily
C2H92_18950	COG1309	transcriptional regulator
C2H92_18955	COG0778	Nitroreductase
C2H92_18960	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C2H92_18965	COG0640	Transcriptional regulator
C2H92_18975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2H92_18980	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_18985	COG4975	Glucose uptake
C2H92_18990	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_18995	COG4549	nuclear export factor GLE1
C2H92_19000	COG1276	copper resistance
C2H92_19000	COG2372	response to copper ion
C2H92_19005	COG1349	DNA-binding transcription factor activity
C2H92_19020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2H92_19025	COG0246	Mannitol dehydrogenase
C2H92_19030	COG0473	3-isopropylmalate dehydrogenase activity
C2H92_19035	COG0681	Belongs to the peptidase S26 family
C2H92_19040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C2H92_19050	COG0561	phosphatase activity
C2H92_19055	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C2H92_19060	COG1914	H( )-stimulated, divalent metal cation uptake system
C2H92_19065	COG4336	lyase activity
C2H92_19070	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C2H92_19075	COG1984	allophanate hydrolase subunit 2
C2H92_19080	COG1414	Transcriptional regulator
C2H92_19085	COG2755	lipolytic protein G-D-S-L family
C2H92_19095	COG2329	Antibiotic biosynthesis monooxygenase
C2H92_19105	COG4989	oxidoreductase activity
C2H92_19110	COG3711	transcriptional antiterminator
C2H92_19115	COG0318	PFAM AMP-dependent synthetase and ligase
C2H92_19120	COG2226	methyltransferase
C2H92_19125	COG1028	Short-chain dehydrogenase reductase Sdr
C2H92_19130	COG1917	Cupin 2, conserved barrel domain protein
C2H92_19135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_19140	COG3871	stress protein (general stress protein 26)
C2H92_19150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2H92_19155	COG2814	Major facilitator Superfamily
C2H92_19160	COG1522	sequence-specific DNA binding
C2H92_19165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C2H92_19165	COG0551	DNA topoisomerase type I activity
C2H92_19170	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C2H92_19175	COG3706	GGDEF domain
C2H92_19180	COG5298	Protein conserved in bacteria
C2H92_19185	COG1215	transferase activity, transferring glycosyl groups
C2H92_19195	COG0531	amino acid
C2H92_19200	COG0494	nUDIX hydrolase
C2H92_19205	COG0028	Belongs to the TPP enzyme family
C2H92_19215	COG1914	H( )-stimulated, divalent metal cation uptake system
C2H92_19220	COG2261	transglycosylase associated protein
C2H92_19225	COG4876	unkown
C2H92_19230	COG2217	Heavy metal translocating P-type atpase
C2H92_19235	COG3729	General stress protein
C2H92_19240	COG0662	Cupin 2, conserved barrel domain protein
C2H92_19245	COG2329	Antibiotic biosynthesis monooxygenase
C2H92_19255	COG3546	catalase activity
C2H92_19260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C2H92_19265	COG3290	protein histidine kinase activity
C2H92_19270	COG4565	transcriptional regulatory protein
C2H92_19275	COG1301	dicarboxylic acid transport
C2H92_19280	COG0628	permease
C2H92_19285	COG1301	dicarboxylic acid transport
C2H92_19290	COG1131	(ABC) transporter
C2H92_19295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C2H92_19305	COG1960	acyl-CoA dehydrogenase activity
C2H92_19320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C2H92_19325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_19330	COG1181	Belongs to the D-alanine--D-alanine ligase family
C2H92_19335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C2H92_19340	COG0513	Belongs to the DEAD box helicase family
C2H92_19345	COG3402	PFAM membrane-flanked domain
C2H92_19350	COG3428	Bacterial PH domain
C2H92_19355	COG0705	Rhomboid family
C2H92_19360	COG0736	holo-[acyl-carrier-protein] synthase activity
C2H92_19365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C2H92_19370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C2H92_19375	COG0864	Transcriptional regulator
C2H92_19380	COG2337	Toxic component of a toxin-antitoxin (TA) module
C2H92_19385	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_19390	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_19395	COG2172	sigma factor antagonist activity
C2H92_19400	COG2208	phosphoserine phosphatase activity
C2H92_19405	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_19410	COG2172	sigma factor antagonist activity
C2H92_19415	COG1191	sigma factor activity
C2H92_19420	COG2208	phosphoserine phosphatase activity
C2H92_19425	COG2183	response to ionizing radiation
C2H92_19435	COG3091	SprT-like family
C2H92_19485	COG0640	Transcriptional regulator
C2H92_19495	COG1396	sequence-specific DNA binding
C2H92_19520	COG0823	Involved in the tonB-independent uptake of proteins
C2H92_19525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_19560	COG1476	TRANSCRIPTIONal
C2H92_19570	COG3239	Fatty acid desaturase
C2H92_19580	COG1278	Cold shock
C2H92_19585	COG1329	Transcriptional regulator
C2H92_19590	COG2315	Protein conserved in bacteria
C2H92_19595	COG0346	lactoylglutathione lyase activity
C2H92_19615	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C2H92_19630	COG2364	Membrane
C2H92_19635	COG1846	Transcriptional regulator
C2H92_19640	COG0456	acetyltransferase
C2H92_19645	COG2808	Putative FMN-binding domain
C2H92_19655	COG0697	spore germination
C2H92_19660	COG0693	protein deglycase activity
C2H92_19675	COG4257	antibiotic catabolic process
C2H92_19680	COG0456	acetyltransferase
C2H92_19690	COG2030	dehydratase
C2H92_19695	COG0697	spore germination
C2H92_19700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2H92_19705	COG0596	Alpha beta hydrolase
C2H92_19710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2H92_19715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C2H92_19720	COG1522	sequence-specific DNA binding
C2H92_19730	COG2323	membrane
C2H92_19735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2H92_19740	COG1309	transcriptional regulator
C2H92_19750	COG0456	acetyltransferase
C2H92_19760	COG0488	(ABC) transporter
C2H92_19765	COG1113	amino acid transport
C2H92_19770	COG2318	DinB family
C2H92_19775	COG1846	Transcriptional regulator
C2H92_19780	COG2409	Drug exporters of the RND superfamily
C2H92_19780	COG1033	growth of symbiont in host cell
C2H92_19790	COG0778	Nitroreductase
C2H92_19795	COG1846	Transcriptional regulator
C2H92_19800	COG1396	sequence-specific DNA binding
C2H92_19805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C2H92_19815	COG2814	Major facilitator Superfamily
C2H92_19820	COG0730	response to heat
C2H92_19825	COG1802	Transcriptional regulator
C2H92_19830	COG1388	LysM domain
C2H92_19830	COG3858	chitin binding
C2H92_19835	COG1819	glycosyl
C2H92_19845	COG1785	Belongs to the alkaline phosphatase family
C2H92_19860	COG1078	dGTPase activity
C2H92_19865	COG1388	LysM domain
C2H92_19870	COG2814	Major facilitator Superfamily
C2H92_19875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2H92_19885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2H92_19890	COG2723	6-phospho-beta-galactosidase activity
C2H92_19895	COG2188	Transcriptional regulator
C2H92_19900	COG1940	carbohydrate kinase activity
C2H92_19905	COG1482	cell wall glycoprotein biosynthetic process
C2H92_19910	COG4124	Belongs to the glycosyl hydrolase 26 family
C2H92_19955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C2H92_19965	COG1214	PFAM Peptidase M22, glycoprotease
C2H92_19970	COG0456	acetyltransferase
C2H92_19975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C2H92_19980	COG0488	(ABC) transporter
C2H92_19985	COG0315	cyclic pyranopterin monophosphate synthase activity
C2H92_19990	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C2H92_19995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C2H92_20000	COG0805	protein transport
C2H92_20010	COG1266	CAAX protease self-immunity
C2H92_20030	COG1073	alpha beta
C2H92_20035	COG0457	Tetratricopeptide repeat
C2H92_20040	COG1063	alcohol dehydrogenase
C2H92_20045	COG2211	Major facilitator Superfamily
C2H92_20050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2H92_20060	COG2814	Major facilitator Superfamily
C2H92_20065	COG1063	alcohol dehydrogenase
C2H92_20070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C2H92_20075	COG0823	Involved in the tonB-independent uptake of proteins
C2H92_20085	COG2267	carboxylic ester hydrolase activity
C2H92_20095	COG2132	Multicopper oxidase
C2H92_20100	COG1113	amino acid transport
C2H92_20110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C2H92_20115	COG0714	Associated with various cellular activities
C2H92_20120	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C2H92_20130	COG0519	Catalyzes the synthesis of GMP from XMP
C2H92_20130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C2H92_20145	COG2252	PERMEase
C2H92_20155	COG3064	Membrane
C2H92_20165	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C2H92_20175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C2H92_20180	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C2H92_20185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C2H92_20190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C2H92_20195	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C2H92_20200	COG0047	phosphoribosylformylglycinamidine synthase activity
C2H92_20205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C2H92_20210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C2H92_20215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C2H92_20220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C2H92_20225	COG0138	bifunctional purine biosynthesis protein purh
C2H92_20230	COG0151	Belongs to the GarS family
C2H92_20235	COG1522	sequence-specific DNA binding
C2H92_20240	COG0531	amino acid
C2H92_20250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C2H92_20255	COG1470	cell adhesion involved in biofilm formation
C2H92_20260	COG4496	protein, YerC YecD
C2H92_20265	COG0069	glutamate synthase activity
C2H92_20270	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C2H92_20275	COG0210	DNA helicase
C2H92_20280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C2H92_20285	COG4851	CamS sex pheromone cAM373 precursor
C2H92_20290	COG2211	Major facilitator Superfamily
C2H92_20300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C2H92_20305	COG1285	pathogenesis
C2H92_20310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2H92_20315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C2H92_20320	COG0154	amidase activity
C2H92_20325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C2H92_20330	COG1309	transcriptional regulator
C2H92_20335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2H92_20340	COG1597	lipid kinase activity
C2H92_20345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C2H92_20350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2H92_20355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2H92_20360	COG1002	Type II restriction enzyme, methylase subunits
C2H92_20365	COG1061	Type III restriction enzyme res subunit
C2H92_20370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C2H92_20400	COG3391	amine dehydrogenase activity
C2H92_20405	COG0457	Tetratricopeptide repeat
C2H92_20415	COG0217	transcriptional regulatory protein
C2H92_20425	COG1309	transcriptional regulator
C2H92_20430	COG3631	Ketosteroid isomerase-related protein
C2H92_20435	COG0702	epimerase
C2H92_20455	COG3546	catalase activity
C2H92_20460	COG0454	-acetyltransferase
C2H92_20470	COG5578	integral membrane protein
C2H92_20475	COG2972	Histidine kinase
C2H92_20480	COG4753	response regulator
C2H92_20480	COG2207	Transcriptional regulator
C2H92_20485	COG1653	transport
C2H92_20490	COG1175	transmembrane transport
C2H92_20495	COG0395	ABC-type sugar transport system, permease component
C2H92_20500	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C2H92_20505	COG2207	Transcriptional regulator
C2H92_20510	COG2755	lipolytic protein G-D-S-L family
C2H92_20520	COG5578	integral membrane protein
C2H92_20525	COG3401	FG-GAP repeat protein
C2H92_20530	COG3401	FG-GAP repeat protein
C2H92_20540	COG2755	lipolytic protein G-D-S-L family
C2H92_20545	COG1874	Beta-galactosidase
C2H92_20560	COG4209	transmembrane transport
C2H92_20565	COG0395	ABC-type sugar transport system, permease component
C2H92_20570	COG1486	melibiose metabolic process
C2H92_20575	COG2323	membrane
C2H92_20580	COG2329	Antibiotic biosynthesis monooxygenase
C2H92_20585	COG0346	lactoylglutathione lyase activity
C2H92_20595	COG1366	Belongs to the anti-sigma-factor antagonist family
C2H92_20600	COG5583	Uncharacterized small protein (DUF2292)
C2H92_20605	COG0670	Belongs to the BI1 family
C2H92_20610	COG0697	spore germination
C2H92_20620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2H92_20635	COG1368	sulfuric ester hydrolase activity
C2H92_20640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C2H92_20645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2H92_20650	COG1442	glycosyl transferase family 8
C2H92_20655	COG1216	Glycosyl transferase, family 2
C2H92_20660	COG1442	glycosyl transferase family 8
C2H92_20670	COG2223	nitrite transmembrane transporter activity
C2H92_20675	COG1011	Hydrolase
C2H92_20680	COG0531	amino acid
C2H92_20685	COG1012	belongs to the aldehyde dehydrogenase family
C2H92_20690	COG0840	transmembrane signaling receptor activity
C2H92_20695	COG0488	(ABC) transporter
C2H92_20705	COG0789	Transcriptional regulator
C2H92_20710	COG2814	Major facilitator Superfamily
C2H92_20715	COG1404	Belongs to the peptidase S8 family
C2H92_20730	COG0488	(ABC) transporter
C2H92_20735	COG0513	Belongs to the DEAD box helicase family
C2H92_20740	COG0456	acetyltransferase
C2H92_20745	COG2130	NADP-dependent
C2H92_20755	COG1120	ATPase activity
C2H92_20760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_20765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_20770	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C2H92_20790	COG0471	metal ion transport
C2H92_20800	COG3290	protein histidine kinase activity
C2H92_20805	COG4565	transcriptional regulatory protein
C2H92_20810	COG3181	Tripartite tricarboxylate transporter family receptor
C2H92_20815	COG2851	Citrate transporter
C2H92_20820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2H92_20825	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C2H92_20830	COG1254	Belongs to the acylphosphatase family
C2H92_20835	COG2258	MOSC domain
C2H92_20855	COG0024	Methionine aminopeptidase
C2H92_20860	COG1263	PTS System
C2H92_20860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H92_20865	COG1368	sulfuric ester hydrolase activity
C2H92_20875	COG1115	amino acid carrier protein
C2H92_20880	COG0697	spore germination
C2H92_20885	COG1263	PTS System
C2H92_20885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H92_20890	COG0366	Alpha amylase catalytic
C2H92_20895	COG2188	Transcriptional regulator
C2H92_20900	COG0778	Nitroreductase
C2H92_20905	COG0737	Belongs to the 5'-nucleotidase family
C2H92_20910	COG0693	protein deglycase activity
C2H92_20915	COG2814	Major facilitator Superfamily
C2H92_20920	COG4840	Belongs to the UPF0435 family
C2H92_20925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C2H92_20930	COG4980	gas vesicle protein
C2H92_20945	COG0477	Major facilitator Superfamily
C2H92_20950	COG0387	Pfam Sodium calcium exchanger
C2H92_20960	COG0668	transmembrane transport
C2H92_20965	COG0535	radical SAM domain protein
C2H92_20975	COG0726	polysaccharide deacetylase
C2H92_20980	COG2084	Dehydrogenase
C2H92_20985	COG0598	Magnesium transport protein CorA
C2H92_20990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C2H92_20995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C2H92_21025	COG1131	(ABC) transporter
C2H92_21035	COG1131	(ABC) transporter
C2H92_21040	COG1668	transmembrane transport
C2H92_21050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2H92_21060	COG4637	Psort location Cytoplasmic, score
C2H92_21070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C2H92_21075	COG0022	dehydrogenase e1 component
C2H92_21080	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2H92_21085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2H92_21090	COG3284	Transcriptional regulator
C2H92_21100	COG1742	UPF0060 membrane protein
C2H92_21125	COG4842	Belongs to the WXG100 family
C2H92_21130	COG1486	melibiose metabolic process
C2H92_21135	COG1737	Transcriptional regulator
C2H92_21140	COG1263	PTS System
C2H92_21140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2H92_21145	COG1132	(ABC) transporter
C2H92_21150	COG1132	(ABC) transporter
C2H92_21155	COG2259	Doxx family
C2H92_21160	COG2514	catechol 2,3-dioxygenase activity
C2H92_21165	COG4585	Histidine kinase
C2H92_21170	COG2197	response regulator
C2H92_21175	COG1131	(ABC) transporter
C2H92_21180	COG0842	Transport permease protein
C2H92_21180	COG1511	domain protein
C2H92_21185	COG0842	Transport permease protein
C2H92_21195	COG1695	Transcriptional regulator
C2H92_21200	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C2H92_21220	COG1131	(ABC) transporter
C2H92_21225	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C2H92_21230	COG1309	transcriptional regulator
C2H92_21235	COG2814	Major facilitator Superfamily
C2H92_21240	COG2318	DinB family
C2H92_21245	COG2814	Major facilitator Superfamily
C2H92_21250	COG1846	Transcriptional regulator
C2H92_21260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2H92_21265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_21270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2H92_21275	COG0384	phenazine biosynthesis protein PhzF