locus-tag	class	description
NM058_00085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NM058_00090	COG1396	sequence-specific DNA binding
NM058_00095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NM058_00100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NM058_00105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NM058_00115	COG0512	Glutamine amidotransferase of anthranilate synthase
NM058_00125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NM058_00130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NM058_00135	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NM058_00140	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NM058_00150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NM058_00155	COG0037	tRNA processing
NM058_00165	COG2304	oxidoreductase activity
NM058_00170	COG2208	phosphoserine phosphatase activity
NM058_00185	COG1098	S1 RNA binding domain
NM058_00190	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NM058_00205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NM058_00215	COG2244	polysaccharide biosynthetic process
NM058_00220	COG2002	toxin-antitoxin pair type II binding
NM058_00240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NM058_00245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NM058_00255	COG2088	sporulation resulting in formation of a cellular spore
NM058_00260	COG0251	oxidation-reduction process
NM058_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NM058_00270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NM058_00280	COG4466	Protein conserved in bacteria
NM058_00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NM058_00295	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NM058_00300	COG3583	domain protein
NM058_00300	COG3584	3D domain protein
NM058_00305	COG0084	hydrolase, TatD family'
NM058_00310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM058_00310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM058_00315	COG2002	toxin-antitoxin pair type II binding
NM058_00325	COG2827	Endonuclease containing a URI domain
NM058_00340	COG1774	PSP1 C-terminal conserved region
NM058_00345	COG0470	DNA polymerase III
NM058_00350	COG1728	Protein conserved in bacteria
NM058_00355	COG3870	Protein conserved in bacteria
NM058_00360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NM058_00365	COG1982	Orn Lys Arg decarboxylase major
NM058_00370	COG3853	Toxic anion resistance protein (TelA)
NM058_00375	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NM058_00420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NM058_00425	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NM058_00430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NM058_00440	COG0590	tRNA wobble adenosine to inosine editing
NM058_00445	COG1335	isochorismatase
NM058_00450	COG1388	LysM domain
NM058_00450	COG3858	chitin binding
NM058_00455	COG1428	Deoxynucleoside kinase
NM058_00460	COG1428	Deoxynucleoside kinase
NM058_00470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NM058_00475	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NM058_00485	COG1686	Belongs to the peptidase S11 family
NM058_00490	COG0516	GMP reductase activity
NM058_00490	COG0517	IMP dehydrogenase activity
NM058_00540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NM058_00545	COG2501	S4 domain
NM058_00550	COG0592	DNA-directed DNA polymerase activity
NM058_00555	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NM058_00565	COG0594	ribonuclease P activity
NM058_00570	COG0706	membrane insertase activity
NM058_00575	COG1847	R3H domain protein
NM058_00580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NM058_00585	COG0445	tRNA wobble uridine modification
NM058_00590	COG0357	Ribosomal RNA small subunit methyltransferase G
NM058_00595	COG1475	DNA binding
NM058_00605	COG1192	Involved in chromosome partitioning
NM058_00610	COG1475	DNA binding
NM058_00620	COG3949	Membrane
NM058_00625	COG4481	Protein conserved in bacteria
NM058_00630	COG0243	molybdopterin cofactor binding
NM058_00635	COG0012	GTP binding
NM058_00640	COG0360	Binds together with S18 to 16S ribosomal RNA
NM058_00650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NM058_00655	COG0708	Exodeoxyribonuclease III
NM058_00665	COG0346	lactoylglutathione lyase activity
NM058_00670	COG0477	Major facilitator Superfamily
NM058_00670	COG2814	Major facilitator Superfamily
NM058_00680	COG1331	Highly conserved protein containing a thioredoxin domain
NM058_00690	COG2856	Zn peptidase
NM058_00720	COG0789	Transcriptional regulator
NM058_00730	COG2315	Protein conserved in bacteria
NM058_00745	COG2364	Membrane
NM058_00750	COG2153	protein acetylation
NM058_00755	COG1846	Transcriptional regulator
NM058_00765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM058_00800	COG2153	protein acetylation
NM058_00805	COG0583	DNA-binding transcription factor activity
NM058_00810	COG2814	Major facilitator Superfamily
NM058_00815	COG1357	PFAM Pentapeptide repeats (8 copies)
NM058_00820	COG4319	ketosteroid isomerase
NM058_00830	COG2271	Major facilitator Superfamily
NM058_00840	COG1227	inorganic diphosphatase activity
NM058_00845	COG1733	regulation of RNA biosynthetic process
NM058_00850	COG5577	PFAM Coat F domain
NM058_00875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NM058_00885	COG3093	addiction module antidote protein HigA
NM058_00900	COG0305	Participates in initiation and elongation during chromosome replication
NM058_00905	COG0346	lactoylglutathione lyase activity
NM058_00935	COG0745	RESPONSE REGULATOR receiver
NM058_00945	COG4863	YycH protein
NM058_00950	COG4853	Protein conserved in bacteria
NM058_00955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NM058_00960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NM058_00990	COG3829	transcription factor binding
NM058_00995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NM058_01000	COG0833	amino acid
NM058_01005	COG0010	Belongs to the arginase family
NM058_01015	COG0457	Tetratricopeptide repeat
NM058_01020	COG0456	acetyltransferase
NM058_01025	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NM058_01060	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NM058_01080	COG2188	Transcriptional regulator
NM058_01085	COG1263	PTS System
NM058_01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM058_01085	COG2190	(PTS) system
NM058_01090	COG2723	6-phospho-beta-galactosidase activity
NM058_01100	COG3634	alkyl hydroperoxide reductase activity
NM058_01105	COG0450	alkyl hydroperoxide reductase
NM058_01110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NM058_01120	COG1070	Carbohydrate kinase
NM058_01125	COG1802	Transcriptional regulator
NM058_01130	COG1929	Belongs to the glycerate kinase type-1 family
NM058_01135	COG5039	Polysaccharide pyruvyl transferase
NM058_01155	COG1346	cytolysis
NM058_01160	COG1380	Effector of murein hydrolase LrgA
NM058_01165	COG1846	Transcriptional regulator
NM058_01170	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_01175	COG1309	transcriptional regulator
NM058_01190	COG1714	RDD family
NM058_01195	COG0789	Transcriptional regulator
NM058_01210	COG1012	belongs to the aldehyde dehydrogenase family
NM058_01220	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_01230	COG0326	Molecular chaperone. Has ATPase activity
NM058_01255	COG2271	Major facilitator Superfamily
NM058_01270	COG0667	Aldo Keto reductase
NM058_01275	COG1349	DNA-binding transcription factor activity
NM058_01280	COG1012	belongs to the aldehyde dehydrogenase family
NM058_01290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NM058_01305	COG2814	Major facilitator Superfamily
NM058_01310	COG0673	inositol 2-dehydrogenase activity
NM058_01315	COG1082	Xylose isomerase domain protein TIM barrel
NM058_01320	COG1082	Xylose isomerase domain protein TIM barrel
NM058_01325	COG0191	fructose-bisphosphate aldolase activity
NM058_01330	COG0745	RESPONSE REGULATOR receiver
NM058_01355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM058_01385	COG0561	phosphatase activity
NM058_01395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM058_01400	COG0456	acetyltransferase
NM058_01405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM058_01415	COG1126	abc transporter atp-binding protein
NM058_01420	COG1473	amidohydrolase
NM058_01425	COG2079	MmgE PrpD family protein
NM058_01440	COG2390	Transcriptional regulator
NM058_01445	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NM058_01450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NM058_01455	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NM058_01460	COG0833	amino acid
NM058_01475	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NM058_01480	COG2986	histidine ammonia-lyase
NM058_01495	COG3507	Belongs to the glycosyl hydrolase 43 family
NM058_01535	COG5444	nuclease activity
NM058_01575	COG2723	6-phospho-beta-galactosidase activity
NM058_01580	COG0589	response to stress
NM058_01585	COG0861	Integral membrane protein TerC family
NM058_01595	COG0697	spore germination
NM058_01685	COG3401	FG-GAP repeat protein
NM058_01685	COG2755	lipolytic protein G-D-S-L family
NM058_01690	COG0513	Belongs to the DEAD box helicase family
NM058_01695	COG2270	Major facilitator Superfamily
NM058_01705	COG3711	transcriptional antiterminator
NM058_01710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM058_01710	COG1263	PTS System
NM058_01710	COG2190	(PTS) system
NM058_01715	COG2723	6-phospho-beta-galactosidase activity
NM058_01720	COG2273	Hydrolase Family 16
NM058_01725	COG2851	Citrate transporter
NM058_01730	COG0693	protein deglycase activity
NM058_01730	COG0753	catalase activity
NM058_01745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NM058_01750	COG0500	methyltransferase
NM058_01755	COG2610	gluconate transmembrane transporter activity
NM058_01760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NM058_01765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NM058_01775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NM058_01785	COG4894	glucomannan catabolic process
NM058_01795	COG2195	Cleaves the N-terminal amino acid of tripeptides
NM058_01800	COG2197	response regulator
NM058_01805	COG4585	Histidine kinase
NM058_01815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NM058_01825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM058_01830	COG1012	belongs to the aldehyde dehydrogenase family
NM058_01850	COG0726	polysaccharide deacetylase
NM058_01860	COG3493	citrate carrier protein
NM058_01865	COG1271	oxidase subunit
NM058_01870	COG1294	oxidase, subunit
NM058_01875	COG4988	ABC transporter
NM058_01880	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NM058_01890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NM058_01895	COG1595	DNA-templated transcription, initiation
NM058_01915	COG1131	(ABC) transporter
NM058_01920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NM058_01925	COG2814	Major facilitator Superfamily
NM058_01930	COG0753	catalase activity
NM058_01935	COG2094	Belongs to the DNA glycosylase MPG family
NM058_01950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM058_01965	COG1486	melibiose metabolic process
NM058_01970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NM058_01975	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NM058_01980	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NM058_01985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_01990	COG1696	Membrane protein involved in D-alanine export
NM058_01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_02010	COG1575	Belongs to the MenA family. Type 1 subfamily
NM058_02015	COG2357	RelA SpoT domain protein
NM058_02020	COG2814	Major facilitator Superfamily
NM058_02050	COG5522	Integral membrane protein (intg_mem_TP0381)
NM058_02060	COG3711	transcriptional antiterminator
NM058_02075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM058_02085	COG0346	lactoylglutathione lyase activity
NM058_02090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NM058_02095	COG4895	conserved protein (DUF2196)
NM058_02105	COG1346	cytolysis
NM058_02110	COG1380	Effector of murein hydrolase LrgA
NM058_02115	COG0583	DNA-binding transcription factor activity
NM058_02120	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NM058_02125	COG0352	thiamine-phosphate diphosphorylase activity
NM058_02130	COG0672	)-iron permease
NM058_02145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NM058_02150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NM058_02155	COG3162	membrane
NM058_02170	COG2246	polysaccharide biosynthetic process
NM058_02175	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NM058_02180	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NM058_02185	COG2261	transglycosylase associated protein
NM058_02190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NM058_02220	COG0778	Nitroreductase
NM058_02225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM058_02230	COG1404	Belongs to the peptidase S8 family
NM058_02265	COG0351	phosphomethylpyrimidine kinase
NM058_02270	COG1216	Glycosyl transferase, family 2
NM058_02275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NM058_02290	COG2233	PERMEase
NM058_02295	COG2363	Small membrane protein
NM058_02305	COG0463	Glycosyl transferase, family 2
NM058_02310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NM058_02325	COG0456	acetyltransferase
NM058_02335	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NM058_02340	COG1088	dTDP-glucose 4,6-dehydratase activity
NM058_02345	COG1091	dTDP-4-dehydrorhamnose reductase activity
NM058_02350	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NM058_02360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NM058_02365	COG1012	belongs to the aldehyde dehydrogenase family
NM058_02370	COG4187	Peptidase family M20/M25/M40
NM058_02385	COG0077	Prephenate dehydratase
NM058_02390	COG1917	Cupin 2, conserved barrel domain protein
NM058_02395	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_02405	COG2814	Major facilitator Superfamily
NM058_02415	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_02420	COG3253	May function as heme-dependent peroxidase
NM058_02425	COG0280	phosphate acetyltransferase
NM058_02430	COG0583	DNA-binding transcription factor activity
NM058_02435	COG0095	Lipoate-protein ligase
NM058_02445	COG0697	spore germination
NM058_02455	COG4844	belongs to the
NM058_02460	COG1078	dGTPase activity
NM058_02465	COG3465	dGTPase activity
NM058_02470	COG1959	2 iron, 2 sulfur cluster binding
NM058_02490	COG1846	Transcriptional regulator
NM058_02495	COG1942	4-Oxalocrotonate Tautomerase
NM058_02500	COG1994	Peptidase M50
NM058_02515	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NM058_02520	COG0010	Belongs to the arginase family
NM058_02535	COG0457	Tetratricopeptide repeat
NM058_02540	COG3391	amine dehydrogenase activity
NM058_02560	COG0612	Peptidase, M16
NM058_02570	COG1131	(ABC) transporter
NM058_02580	COG0535	radical SAM domain protein
NM058_02595	COG4506	Protein conserved in bacteria
NM058_02600	COG0018	arginyl-trna synthetase
NM058_02610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NM058_02620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NM058_02625	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NM058_02630	COG1140	nitrate reductase beta subunit
NM058_02640	COG2181	nitrate reductase activity
NM058_02655	COG1132	(ABC) transporter
NM058_02660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NM058_02670	COG4294	response to UV
NM058_02675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NM058_02680	COG2181	nitrate reductase activity
NM058_02680	COG0247	lactate metabolic process
NM058_02685	COG1960	acyl-CoA dehydrogenase activity
NM058_02690	COG3343	RNA polymerase activity
NM058_02700	COG4821	SIS domain
NM058_02710	COG0191	fructose-bisphosphate aldolase activity
NM058_02715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NM058_02720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NM058_02725	COG1494	fructose-1,6-bisphosphatase
NM058_02730	COG1494	fructose-1,6-bisphosphatase
NM058_02750	COG1435	thymidine kinase activity
NM058_02755	COG0281	malic enzyme
NM058_02760	COG0679	Auxin Efflux Carrier
NM058_02765	COG0789	Transcriptional regulator
NM058_02770	COG0346	lactoylglutathione lyase activity
NM058_02775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NM058_02780	COG2890	protein-(glutamine-N5) methyltransferase activity
NM058_02800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NM058_02805	COG0009	L-threonylcarbamoyladenylate synthase
NM058_02810	COG1971	Probably functions as a manganese efflux pump
NM058_02815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NM058_02820	COG0698	ribose 5-phosphate isomerase
NM058_02825	COG4475	Protein of unknown function (DUF436)
NM058_02830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NM058_02835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NM058_02845	COG0356	it plays a direct role in the translocation of protons across the membrane
NM058_02865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NM058_02870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NM058_02875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NM058_02890	COG4836	Membrane
NM058_02900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NM058_02905	COG2385	sporulation resulting in formation of a cellular spore
NM058_02910	COG2304	oxidoreductase activity
NM058_02915	COG2304	oxidoreductase activity
NM058_02925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NM058_02930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NM058_02935	COG0457	Tetratricopeptide repeat
NM058_02945	COG3237	CsbD-like
NM058_02975	COG0831	urea catabolic process
NM058_02980	COG0832	Belongs to the urease beta subunit family
NM058_02985	COG0804	urea catabolic process
NM058_02990	COG1959	2 iron, 2 sulfur cluster binding
NM058_02995	COG2910	NAD(P)H-binding
NM058_03005	COG0789	Transcriptional regulator
NM058_03020	COG2089	acid synthase
NM058_03035	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NM058_03040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NM058_03060	COG1247	-acetyltransferase
NM058_03080	COG0347	Belongs to the P(II) protein family
NM058_03085	COG0004	ammonium transporteR
NM058_03095	COG1335	isochorismatase
NM058_03105	COG1953	Uracil, thiamine, allantoin
NM058_03110	COG3420	alginic acid biosynthetic process
NM058_03120	COG1846	Transcriptional regulator
NM058_03130	COG1609	Transcriptional regulator
NM058_03145	COG4786	Flagellar basal body rod
NM058_03155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NM058_03160	COG1970	mechanosensitive ion channel activity
NM058_03165	COG2972	Histidine kinase
NM058_03165	COG0745	RESPONSE REGULATOR receiver
NM058_03175	COG3279	Response regulator of the LytR AlgR family
NM058_03190	COG2602	Beta-lactamase
NM058_03205	COG0629	single-stranded DNA binding
NM058_03210	COG1349	DNA-binding transcription factor activity
NM058_03215	COG0561	phosphatase activity
NM058_03220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NM058_03225	COG4715	Zinc finger, swim domain protein
NM058_03235	COG3944	biosynthesis protein
NM058_03240	COG0489	protein tyrosine kinase activity
NM058_03250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NM058_03265	COG5444	nuclease activity
NM058_03290	COG0655	NAD(P)H dehydrogenase (quinone) activity
NM058_03300	COG2059	Chromate
NM058_03305	COG2059	Chromate
NM058_03310	COG1522	sequence-specific DNA binding
NM058_03325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NM058_03335	COG5337	Spore coat protein CotH
NM058_03340	COG0583	DNA-binding transcription factor activity
NM058_03345	COG0028	Belongs to the TPP enzyme family
NM058_03350	COG3527	Alpha-acetolactate decarboxylase
NM058_03365	COG3103	Sh3 type 3 domain protein
NM058_03375	COG1172	Belongs to the binding-protein-dependent transport system permease family
NM058_03385	COG1869	D-ribose catabolic process
NM058_03390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NM058_03400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NM058_03420	COG0791	NLP P60 protein
NM058_03425	COG0561	phosphatase activity
NM058_03430	COG1316	TRANSCRIPTIONal
NM058_03455	COG1482	cell wall glycoprotein biosynthetic process
NM058_03495	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NM058_03505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NM058_03515	COG0463	Glycosyl transferase, family 2
NM058_03515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NM058_03520	COG1181	Belongs to the D-alanine--D-alanine ligase family
NM058_03530	COG1215	transferase activity, transferring glycosyl groups
NM058_03540	COG1682	transport, permease protein
NM058_03545	COG1134	teichoic acid transport
NM058_03550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NM058_03580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NM058_03625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NM058_03630	COG3307	-O-antigen
NM058_03635	COG3206	protein involved in exopolysaccharide biosynthesis
NM058_03645	COG0438	transferase activity, transferring glycosyl groups
NM058_03650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NM058_03660	COG1739	Uncharacterized protein family UPF0029
NM058_03670	COG2197	response regulator
NM058_03675	COG1307	EDD domain protein, DegV family
NM058_03680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NM058_03690	COG1040	competence protein
NM058_03700	COG2747	anti-sigma28 factor FlgM
NM058_03705	COG3418	PFAM FlgN family protein
NM058_03710	COG4786	Flagellar basal body rod
NM058_03710	COG1256	bacterial-type flagellum assembly
NM058_03715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM058_03725	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NM058_03730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NM058_03735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM058_03740	COG1334	flagellar protein FlaG
NM058_03745	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NM058_03750	COG1516	flagellar protein fliS
NM058_03765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NM058_03780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM058_03785	COG2010	Cytochrome c
NM058_03790	COG2884	Cell division ATP-binding protein ftsE
NM058_03795	COG2177	Part of the ABC transporter FtsEX involved in
NM058_03800	COG3409	Peptidoglycan-binding domain 1 protein
NM058_03800	COG0793	Belongs to the peptidase S41A family
NM058_03820	COG1309	transcriptional regulator
NM058_03835	COG4897	Protein conserved in bacteria
NM058_03840	COG0556	nucleotide-excision repair
NM058_03850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NM058_03865	COG3595	metallopeptidase activity
NM058_03870	COG1983	PspC domain protein
NM058_03885	COG2814	Major facilitator Superfamily
NM058_03895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NM058_03900	COG2188	Transcriptional regulator
NM058_03920	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NM058_03925	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NM058_03935	COG0110	maltose O-acetyltransferase activity
NM058_03940	COG5297	Belongs to the glycosyl hydrolase family 6
NM058_03945	COG4990	cell redox homeostasis
NM058_03965	COG0131	Imidazoleglycerol-phosphate dehydratase
NM058_03975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NM058_03980	COG0107	imidazoleglycerol-phosphate synthase activity
NM058_03985	COG0140	phosphoribosyl-ATP diphosphatase activity
NM058_03985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NM058_04005	COG1132	(ABC) transporter
NM058_04010	COG0457	Tetratricopeptide repeat
NM058_04015	COG0791	NLP P60 protein
NM058_04015	COG3883	PFAM NLP P60 protein
NM058_04020	COG0492	ferredoxin-NADP+ reductase activity
NM058_04025	COG1051	belongs to the nudix hydrolase family
NM058_04030	COG1660	Displays ATPase and GTPase activities
NM058_04035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NM058_04045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM058_04050	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NM058_04060	COG0745	RESPONSE REGULATOR receiver
NM058_04065	COG5002	protein histidine kinase activity
NM058_04075	COG0577	efflux transmembrane transporter activity
NM058_04085	COG0288	reversible hydration of carbon dioxide
NM058_04090	COG0659	secondary active sulfate transmembrane transporter activity
NM058_04105	COG1609	Transcriptional regulator
NM058_04115	COG2182	Extracellular solute-binding protein
NM058_04120	COG1175	transmembrane transport
NM058_04125	COG3833	ABC-type maltose transport systems, permease component
NM058_04135	COG1554	hydrolase, family 65, central catalytic
NM058_04145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NM058_04165	COG2076	Multidrug Resistance protein
NM058_04170	COG2076	Multidrug Resistance protein
NM058_04175	COG1309	transcriptional regulator
NM058_04180	COG0531	amino acid
NM058_04185	COG1621	beta-fructofuranosidase activity
NM058_04190	COG1621	beta-fructofuranosidase activity
NM058_04200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NM058_04205	COG1794	racemase activity, acting on amino acids and derivatives
NM058_04215	COG3479	Phenolic acid decarboxylase
NM058_04230	COG1396	sequence-specific DNA binding
NM058_04245	COG1086	Polysaccharide biosynthesis protein
NM058_04250	COG0438	transferase activity, transferring glycosyl groups
NM058_04255	COG1215	transferase activity, transferring glycosyl groups
NM058_04260	COG0438	transferase activity, transferring glycosyl groups
NM058_04270	COG1216	Glycosyl transferase, family 2
NM058_04275	COG5039	Polysaccharide pyruvyl transferase
NM058_04290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NM058_04295	COG0110	maltose O-acetyltransferase activity
NM058_04305	COG5039	Polysaccharide pyruvyl transferase
NM058_04315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NM058_04325	COG2186	Transcriptional regulator
NM058_04330	COG1609	Transcriptional regulator
NM058_04340	COG1175	transmembrane transport
NM058_04345	COG3833	ABC-type maltose transport systems, permease component
NM058_04350	COG1874	Beta-galactosidase
NM058_04355	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NM058_04360	COG2208	phosphoserine phosphatase activity
NM058_04375	COG0842	Transport permease protein
NM058_04390	COG0247	lactate metabolic process
NM058_04395	COG1139	Iron-sulfur cluster binding protein
NM058_04400	COG1556	Lactate utilization protein
NM058_04405	COG3858	chitin binding
NM058_04410	COG1113	amino acid transport
NM058_04420	COG0583	DNA-binding transcription factor activity
NM058_04425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM058_04430	COG1609	Transcriptional regulator
NM058_04435	COG2814	Major facilitator Superfamily
NM058_04440	COG2390	Transcriptional regulator
NM058_04450	COG0126	phosphoglycerate kinase activity
NM058_04460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NM058_04470	COG0456	acetyltransferase
NM058_04475	COG4640	response to antibiotic
NM058_04480	COG3064	Membrane
NM058_04490	COG1510	regulation of RNA biosynthetic process
NM058_04500	COG1174	glycine betaine transport
NM058_04505	COG1732	Glycine betaine
NM058_04510	COG1174	glycine betaine transport
NM058_04525	COG1174	glycine betaine transport
NM058_04530	COG1732	Glycine betaine
NM058_04535	COG1174	glycine betaine transport
NM058_04540	COG0840	transmembrane signaling receptor activity
NM058_04545	COG1733	regulation of RNA biosynthetic process
NM058_04550	COG1396	sequence-specific DNA binding
NM058_04555	COG1396	sequence-specific DNA binding
NM058_04570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NM058_04575	COG1647	Serine aminopeptidase, S33
NM058_04580	COG0557	exoribonuclease II activity
NM058_04585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NM058_04605	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_04610	COG1309	transcriptional regulator
NM058_04615	COG2076	Multidrug Resistance protein
NM058_04625	COG1289	transmembrane transporter activity
NM058_04630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NM058_04640	COG1937	Protein conserved in bacteria
NM058_04645	COG2608	mercury ion transmembrane transporter activity
NM058_04650	COG2217	Heavy metal translocating P-type atpase
NM058_04660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NM058_04665	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NM058_04685	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NM058_04700	COG0656	L-ascorbic acid biosynthetic process
NM058_04705	COG4149	molybdate abc transporter
NM058_04710	COG0725	ABC transporter, periplasmic molybdate-binding protein
NM058_04715	COG1910	domain protein
NM058_04720	COG1368	sulfuric ester hydrolase activity
NM058_04725	COG1988	membrane-bound metal-dependent
NM058_04735	COG0531	amino acid
NM058_04750	COG0640	Transcriptional regulator
NM058_04755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM058_04760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM058_04775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NM058_04780	COG1136	(ABC) transporter
NM058_04785	COG0577	efflux transmembrane transporter activity
NM058_04805	COG1191	sigma factor activity
NM058_04815	COG0745	RESPONSE REGULATOR receiver
NM058_04820	COG2205	protein histidine kinase activity
NM058_04825	COG3386	PFAM SMP-30 Gluconolaconase
NM058_04835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM058_04850	COG2096	Adenosyltransferase
NM058_04860	COG4758	membrane
NM058_04865	COG1842	Phage shock protein A
NM058_04870	COG3595	metallopeptidase activity
NM058_04880	COG4585	Histidine kinase
NM058_04885	COG2197	response regulator
NM058_04895	COG0814	amino acid
NM058_04900	COG0697	spore germination
NM058_04910	COG0114	fumarate hydratase activity
NM058_04915	COG1309	transcriptional regulator
NM058_04925	COG2770	Histidine kinase
NM058_04925	COG2205	protein histidine kinase activity
NM058_04930	COG0745	RESPONSE REGULATOR receiver
NM058_04935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NM058_04940	COG0783	Belongs to the Dps family
NM058_04945	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_04960	COG1120	ATPase activity
NM058_04970	COG0583	DNA-binding transcription factor activity
NM058_04975	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_04980	COG1942	4-Oxalocrotonate Tautomerase
NM058_04990	COG1846	Transcriptional regulator
NM058_04995	COG5577	PFAM Coat F domain
NM058_05005	COG0506	proline dehydrogenase activity
NM058_05020	COG0183	Belongs to the thiolase family
NM058_05030	COG1393	Belongs to the ArsC family
NM058_05035	COG0509	glycine decarboxylation via glycine cleavage system
NM058_05045	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NM058_05050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_05060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NM058_05065	COG2011	ABC-type metal ion transport system permease component
NM058_05070	COG1464	Belongs to the NlpA lipoprotein family
NM058_05075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NM058_05085	COG0396	ATPase activity
NM058_05090	COG0719	Fe-S assembly protein
NM058_05100	COG0822	iron-sulfur transferase activity
NM058_05105	COG0719	Fe-S assembly protein
NM058_05110	COG0640	Transcriptional regulator
NM058_05115	COG0346	lactoylglutathione lyase activity
NM058_05130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NM058_05135	COG0322	excinuclease ABC activity
NM058_05140	COG2222	sugar isomerase
NM058_05145	COG1653	transport
NM058_05155	COG0395	ABC-type sugar transport system, permease component
NM058_05165	COG2188	Transcriptional regulator
NM058_05170	COG3842	ATPase activity
NM058_05175	COG2356	endonuclease I
NM058_05190	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NM058_05195	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NM058_05200	COG2068	MobA-Related Protein
NM058_05205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NM058_05210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NM058_05215	COG2080	2 iron, 2 sulfur cluster binding
NM058_05245	COG2351	hydroxyisourate hydrolase activity
NM058_05260	COG2233	PERMEase
NM058_05265	COG2508	Transcriptional regulator
NM058_05270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NM058_05280	COG1801	Protein of unknown function DUF72
NM058_05285	COG0730	response to heat
NM058_05290	COG0737	Belongs to the 5'-nucleotidase family
NM058_05295	COG3377	Domain of unknown function (DUF1805)
NM058_05310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NM058_05320	COG4470	Protein conserved in bacteria
NM058_05325	COG2445	Protein of unknown function DUF86
NM058_05330	COG0647	UMP catabolic process
NM058_05335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NM058_05340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NM058_05345	COG0460	homoserine dehydrogenase
NM058_05355	COG0083	homoserine kinase activity
NM058_05360	COG4946	Tricorn protease homolog
NM058_05360	COG0823	Involved in the tonB-independent uptake of proteins
NM058_05360	COG1506	peptidase
NM058_05370	COG4837	Protein of unknown function (DUF1462)
NM058_05375	COG1252	NADH dehydrogenase
NM058_05380	COG4844	belongs to the
NM058_05390	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NM058_05400	COG0456	acetyltransferase
NM058_05405	COG2808	Putative FMN-binding domain
NM058_05410	COG0516	GMP reductase activity
NM058_05420	COG0492	ferredoxin-NADP+ reductase activity
NM058_05440	COG3584	3D domain protein
NM058_05445	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NM058_05455	COG2056	Na+-H+ antiporter family
NM058_05460	COG1268	BioY protein
NM058_05470	COG2819	hydrolase of the alpha beta superfamily
NM058_05475	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_05480	COG1169	isochorismate synthase
NM058_05485	COG1021	2,3-dihydroxybenzoate-AMP ligase
NM058_05490	COG1535	isochorismatase
NM058_05490	COG3433	isochorismatase activity
NM058_05500	COG3251	PFAM MbtH domain protein
NM058_05505	COG5634	Uncharacterized conserved protein (DUF2278)
NM058_05510	COG0686	Belongs to the AlaDH PNT family
NM058_05515	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NM058_05515	COG2508	Transcriptional regulator
NM058_05520	COG4842	Belongs to the WXG100 family
NM058_05525	COG5417	Belongs to the EsaB family
NM058_05535	COG1674	ftsk spoiiie
NM058_05535	COG0433	COG0433 Predicted ATPase
NM058_05545	COG1511	domain protein
NM058_05555	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_05560	COG1418	mRNA catabolic process
NM058_05575	COG0628	permease
NM058_05595	COG1335	isochorismatase
NM058_05600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NM058_05605	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NM058_05625	COG0142	geranyltranstransferase activity
NM058_05635	COG4585	Histidine kinase
NM058_05640	COG2197	response regulator
NM058_05645	COG2050	protein possibly involved in aromatic compounds catabolism
NM058_05650	COG1320	monovalent cation:proton antiporter activity
NM058_05655	COG2212	antiporter activity
NM058_05665	COG0651	ATP synthesis coupled electron transport
NM058_05670	COG1006	Multisubunit Na H antiporter MnhC subunit
NM058_05675	COG2111	Na H antiporter
NM058_05680	COG2111	Na H antiporter
NM058_05680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NM058_05690	COG3493	citrate carrier protein
NM058_05695	COG1079	Belongs to the binding-protein-dependent transport system permease family
NM058_05710	COG1744	ABC transporter substrate-binding protein PnrA-like
NM058_05715	COG4565	transcriptional regulatory protein
NM058_05720	COG3290	protein histidine kinase activity
NM058_05730	COG3011	Protein conserved in bacteria
NM058_05740	COG2814	Major facilitator Superfamily
NM058_05750	COG5018	Exonuclease
NM058_05760	COG2205	protein histidine kinase activity
NM058_05765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NM058_05775	COG2267	carboxylic ester hydrolase activity
NM058_05780	COG1522	sequence-specific DNA binding
NM058_05785	COG0436	Aminotransferase
NM058_05795	COG2155	Conserved Protein
NM058_05805	COG1979	alcohol dehydrogenase
NM058_05810	COG0166	Belongs to the GPI family
NM058_05840	COG2738	Putative neutral zinc metallopeptidase
NM058_05845	COG1253	flavin adenine dinucleotide binding
NM058_05850	COG0366	Alpha amylase catalytic
NM058_05855	COG0432	Pfam Uncharacterised protein family UPF0047
NM058_05875	COG0840	transmembrane signaling receptor activity
NM058_05885	COG0840	transmembrane signaling receptor activity
NM058_05890	COG0840	transmembrane signaling receptor activity
NM058_05900	COG1349	DNA-binding transcription factor activity
NM058_05905	COG1070	Carbohydrate kinase
NM058_05910	COG3254	rhamnose metabolic process
NM058_05915	COG4806	L-rhamnose isomerase
NM058_05920	COG0673	inositol 2-dehydrogenase activity
NM058_05930	COG1968	undecaprenyl-diphosphatase activity
NM058_05945	COG0477	Major facilitator Superfamily
NM058_05950	COG1705	Flagellar rod assembly protein muramidase FlgJ
NM058_05955	COG4682	membrane
NM058_05960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NM058_05965	COG0569	domain protein
NM058_05975	COG1510	regulation of RNA biosynthetic process
NM058_05980	COG1012	belongs to the aldehyde dehydrogenase family
NM058_05985	COG1454	alcohol dehydrogenase
NM058_05995	COG2318	DinB family
NM058_06000	COG1585	Membrane protein implicated in regulation of membrane protease activity
NM058_06010	COG1247	-acetyltransferase
NM058_06015	COG3859	Proton-coupled thiamine transporter YuaJ
NM058_06145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NM058_06160	COG0058	SHG alpha-glucan phosphorylase activity
NM058_06165	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NM058_06170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NM058_06180	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NM058_06185	COG0596	Alpha beta hydrolase
NM058_06190	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NM058_06195	COG0318	PFAM AMP-dependent synthetase and ligase
NM058_06200	COG4948	Mandelate Racemase Muconate Lactonizing
NM058_06205	COG0803	Belongs to the bacterial solute-binding protein 9 family
NM058_06210	COG1121	(ABC) transporter
NM058_06220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NM058_06230	COG1294	oxidase, subunit
NM058_06240	COG0254	rRNA binding
NM058_06245	COG0288	reversible hydration of carbon dioxide
NM058_06250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NM058_06255	COG1854	S-ribosylhomocysteine lyase activity
NM058_06270	COG0783	Belongs to the Dps family
NM058_06275	COG4824	toxin secretion phage lysis holin
NM058_06280	COG0494	nUDIX hydrolase
NM058_06290	COG1116	anion transmembrane transporter activity
NM058_06295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NM058_06300	COG1506	peptidase
NM058_06310	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NM058_06320	COG0367	asparagine synthase
NM058_06325	COG1113	amino acid transport
NM058_06330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NM058_06335	COG2267	carboxylic ester hydrolase activity
NM058_06345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NM058_06350	COG1242	4 iron, 4 sulfur cluster binding
NM058_06365	COG1725	Transcriptional regulator
NM058_06370	COG1131	(ABC) transporter
NM058_06390	COG0577	efflux transmembrane transporter activity
NM058_06395	COG0745	RESPONSE REGULATOR receiver
NM058_06405	COG1136	(ABC) transporter
NM058_06410	COG0577	efflux transmembrane transporter activity
NM058_06420	COG2814	Major facilitator Superfamily
NM058_06425	COG2202	Pas domain
NM058_06425	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_06440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NM058_06450	COG0395	ABC-type sugar transport system, permease component
NM058_06465	COG1609	Transcriptional regulator
NM058_06470	COG1073	alpha beta
NM058_06480	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NM058_06485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NM058_06490	COG0156	8-amino-7-oxononanoate synthase activity
NM058_06500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NM058_06505	COG2124	cytochrome p450
NM058_06510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_06520	COG1653	transport
NM058_06550	COG5578	integral membrane protein
NM058_06565	COG2081	HI0933 family
NM058_06570	COG2244	polysaccharide biosynthetic process
NM058_06575	COG1187	pseudouridine synthase activity
NM058_06580	COG1349	DNA-binding transcription factor activity
NM058_06590	COG4473	ABC transporter
NM058_06605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NM058_06610	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NM058_06620	COG1597	lipid kinase activity
NM058_06640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NM058_06645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM058_06655	COG5584	Small secreted protein
NM058_06675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_06680	COG4848	Belongs to the UPF0354 family
NM058_06685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM058_06695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NM058_06700	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NM058_06705	COG4980	gas vesicle protein
NM058_06710	COG3118	belongs to the thioredoxin family
NM058_06730	COG1360	Flagellar Motor Protein
NM058_06735	COG0123	including yeast histone deacetylase and acetoin utilization protein
NM058_06740	COG0517	IMP dehydrogenase activity
NM058_06745	COG0454	-acetyltransferase
NM058_06750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NM058_06755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NM058_06760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NM058_06765	COG2203	Gaf domain
NM058_06765	COG2199	diguanylate cyclase activity
NM058_06770	COG1956	GAF domain-containing protein
NM058_06775	COG1309	transcriptional regulator
NM058_06780	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NM058_06785	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NM058_06790	COG1114	Component of the transport system for branched-chain amino acids
NM058_06800	COG0301	tRNA thio-modification
NM058_06810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NM058_06825	COG0616	signal peptide processing
NM058_06830	COG1714	RDD family
NM058_06845	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NM058_06850	COG0827	DNA restriction-modification system
NM058_06855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NM058_06865	COG0137	argininosuccinate synthase activity
NM058_06870	COG0165	Argininosuccinate lyase
NM058_06875	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_06880	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NM058_06890	COG0454	-acetyltransferase
NM058_06895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM058_06900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM058_06905	COG0765	amino acid transport
NM058_06910	COG0765	amino acid transport
NM058_06915	COG1126	abc transporter atp-binding protein
NM058_06920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM058_06930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM058_06935	COG0196	riboflavin kinase activity
NM058_06945	COG0730	response to heat
NM058_06950	COG4109	DRTGG domain
NM058_06960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NM058_06980	COG0587	DNA-directed DNA polymerase activity
NM058_06985	COG0281	malic enzyme
NM058_06990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NM058_07000	COG0205	6-phosphofructokinase activity
NM058_07005	COG0469	pyruvate kinase activity
NM058_07010	COG3030	protein affecting phage T7 exclusion by the F plasmid
NM058_07015	COG0628	permease
NM058_07020	COG0628	permease
NM058_07025	COG0628	permease
NM058_07030	COG2707	UPF0756 membrane protein
NM058_07035	COG0372	Belongs to the citrate synthase family
NM058_07040	COG0538	isocitrate dehydrogenase activity
NM058_07045	COG0039	L-malate dehydrogenase activity
NM058_07050	COG0745	RESPONSE REGULATOR receiver
NM058_07065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NM058_07070	COG1971	Probably functions as a manganese efflux pump
NM058_07075	COG0237	dephospho-CoA kinase activity
NM058_07080	COG0656	L-ascorbic acid biosynthetic process
NM058_07085	COG2814	Major facilitator Superfamily
NM058_07100	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NM058_07110	COG3611	Membrane attachment protein
NM058_07120	COG0398	Pfam SNARE associated Golgi protein
NM058_07130	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NM058_07135	COG1011	Hydrolase
NM058_07140	COG3275	phosphorelay sensor kinase activity
NM058_07150	COG1380	Effector of murein hydrolase LrgA
NM058_07155	COG1346	cytolysis
NM058_07165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NM058_07170	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NM058_07190	COG1363	Peptidase, m42
NM058_07195	COG3507	Belongs to the glycosyl hydrolase 43 family
NM058_07200	COG2160	L-arabinose isomerase activity
NM058_07205	COG1069	ribulokinase activity
NM058_07210	COG0235	Class ii aldolase
NM058_07220	COG0371	Dehydrogenase
NM058_07230	COG1175	transmembrane transport
NM058_07240	COG3534	alpha-L-arabinofuranosidase
NM058_07245	COG1695	Transcriptional regulator
NM058_07270	COG0346	lactoylglutathione lyase activity
NM058_07280	COG0277	FAD linked oxidase domain protein
NM058_07285	COG3835	regulator
NM058_07295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NM058_07305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NM058_07315	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NM058_07320	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NM058_07325	COG1286	toxin biosynthetic process
NM058_07340	COG3766	membrane
NM058_07345	COG0318	PFAM AMP-dependent synthetase and ligase
NM058_07350	COG1309	transcriptional regulator
NM058_07365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NM058_07375	COG3118	belongs to the thioredoxin family
NM058_07380	COG0322	excinuclease ABC activity
NM058_07385	COG0527	aspartate kinase activity
NM058_07390	COG1719	4-vinyl reductase, 4VR
NM058_07395	COG2009	succinate dehydrogenase
NM058_07400	COG1053	succinate dehydrogenase
NM058_07405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NM058_07415	COG2197	response regulator
NM058_07420	COG1846	Transcriptional regulator
NM058_07425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NM058_07430	COG5401	PFAM Sporulation and spore germination
NM058_07440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NM058_07445	COG0622	Phosphoesterase
NM058_07455	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NM058_07460	COG0454	-acetyltransferase
NM058_07475	COG0440	acetolactate synthase activity
NM058_07480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NM058_07485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NM058_07490	COG0473	3-isopropylmalate dehydrogenase activity
NM058_07495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NM058_07500	COG0066	3-isopropylmalate dehydratase activity
NM058_07505	COG1477	protein flavinylation
NM058_07505	COG0457	Tetratricopeptide repeat
NM058_07510	COG0544	peptidyl-prolyl cis-trans isomerase activity
NM058_07515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NM058_07525	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NM058_07530	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NM058_07540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NM058_07555	COG1587	Uroporphyrinogen-III synthase
NM058_07565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NM058_07570	COG1388	LysM domain
NM058_07575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NM058_07585	COG0525	valine-tRNA ligase activity
NM058_07605	COG0424	maF-like protein
NM058_07785	COG5280	Phage tail tape measure protein TP901
NM058_07785	COG3953	SLT domain
NM058_07795	COG1705	Flagellar rod assembly protein muramidase FlgJ
NM058_07835	COG5632	N-Acetylmuramoyl-L-alanine amidase
NM058_07835	COG3409	Peptidoglycan-binding domain 1 protein
NM058_07835	COG1388	LysM domain
NM058_07850	COG0457	Tetratricopeptide repeat
NM058_07895	COG1077	Cell shape determining protein MreB Mrl
NM058_07905	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NM058_07910	COG0850	regulation of cytokinetic process
NM058_07915	COG2894	cell division
NM058_07920	COG0739	heme binding
NM058_07930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NM058_07935	COG2868	ribosomal protein
NM058_07940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NM058_07950	COG3290	protein histidine kinase activity
NM058_07955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NM058_07960	COG4492	Belongs to the UPF0735 family
NM058_07965	COG0077	Prephenate dehydratase
NM058_07970	COG1827	regulation of RNA biosynthetic process
NM058_07975	COG1104	cysteine desulfurase activity
NM058_07985	COG0157	Belongs to the NadC ModD family
NM058_07990	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NM058_08010	COG1115	amino acid carrier protein
NM058_08030	COG2112	serine threonine protein kinase
NM058_08035	COG0673	inositol 2-dehydrogenase activity
NM058_08040	COG2814	Major facilitator Superfamily
NM058_08050	COG0632	four-way junction helicase activity
NM058_08055	COG2255	four-way junction helicase activity
NM058_08065	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NM058_08075	COG1862	Preprotein translocase
NM058_08085	COG2323	membrane
NM058_08090	COG2244	polysaccharide biosynthetic process
NM058_08100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NM058_08100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NM058_08105	COG0490	domain, Protein
NM058_08110	COG5416	Lipopolysaccharide assembly protein A domain
NM058_08120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NM058_08125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NM058_08130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NM058_08135	COG1490	D-aminoacyl-tRNA deacylase activity
NM058_08140	COG4991	sh3 domain protein
NM058_08140	COG3103	Sh3 type 3 domain protein
NM058_08140	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM058_08150	COG0124	histidyl-tRNA synthetase
NM058_08165	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NM058_08170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NM058_08175	COG1959	2 iron, 2 sulfur cluster binding
NM058_08180	COG1104	cysteine desulfurase activity
NM058_08185	COG0482	sulfurtransferase activity
NM058_08190	COG0457	Tetratricopeptide repeat
NM058_08195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NM058_08200	COG3881	PFAM PRC-barrel domain
NM058_08215	COG0765	amino acid transport
NM058_08220	COG0765	amino acid transport
NM058_08230	COG1126	abc transporter atp-binding protein
NM058_08240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NM058_08245	COG4472	Bacterial protein of unknown function (DUF965)
NM058_08250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NM058_08255	COG3906	Belongs to the UPF0473 family
NM058_08260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NM058_08265	COG4122	O-methyltransferase activity
NM058_08270	COG0826	peptidase U32
NM058_08280	COG0572	uridine kinase
NM058_08285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NM058_08305	COG2226	methyltransferase
NM058_08310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NM058_08315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NM058_08320	COG0626	cystathionine gamma-synthase activity
NM058_08330	COG2427	Protein of unknown function (DUF1641)
NM058_08335	COG3383	formate dehydrogenase (NAD+) activity
NM058_08340	COG5609	conserved protein (DUF2294)
NM058_08345	COG2116	formate transmembrane transporter activity
NM058_08360	COG2226	methyltransferase
NM058_08390	COG1595	DNA-templated transcription, initiation
NM058_08400	COG1280	lysine exporter protein (LysE YggA)
NM058_08420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM058_08430	COG3715	PTS system
NM058_08435	COG3716	PTS system mannose fructose sorbose family IID component
NM058_08445	COG1621	beta-fructofuranosidase activity
NM058_08460	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NM058_08470	COG0789	Transcriptional regulator
NM058_08475	COG0789	Transcriptional regulator
NM058_08480	COG2207	Transcriptional regulator
NM058_08485	COG0667	Aldo Keto reductase
NM058_08495	COG5577	PFAM Coat F domain
NM058_08510	COG5577	PFAM Coat F domain
NM058_08520	COG4991	sh3 domain protein
NM058_08525	COG4991	sh3 domain protein
NM058_08530	COG0110	maltose O-acetyltransferase activity
NM058_08535	COG0697	spore germination
NM058_08540	COG0596	Alpha beta hydrolase
NM058_08545	COG5566	PFAM Mor transcription activator
NM058_08550	COG3409	Peptidoglycan-binding domain 1 protein
NM058_08555	COG0667	Aldo Keto reductase
NM058_08560	COG1595	DNA-templated transcription, initiation
NM058_08565	COG3443	Belongs to the bacterial solute-binding protein 9 family
NM058_08575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NM058_08580	COG4608	Belongs to the ABC transporter superfamily
NM058_08585	COG0444	Belongs to the ABC transporter superfamily
NM058_08590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM058_08595	COG0601	transmembrane transport
NM058_08600	COG0747	negative chemotaxis
NM058_08630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM058_08635	COG0477	Major facilitator Superfamily
NM058_08640	COG0456	acetyltransferase
NM058_08645	COG2318	DinB family
NM058_08650	COG1802	Transcriptional regulator
NM058_08655	COG0697	spore germination
NM058_08660	COG1917	Cupin 2, conserved barrel domain protein
NM058_08660	COG2207	Transcriptional regulator
NM058_08670	COG4124	Belongs to the glycosyl hydrolase 26 family
NM058_08675	COG0583	DNA-binding transcription factor activity
NM058_08680	COG0697	spore germination
NM058_08690	COG0583	DNA-binding transcription factor activity
NM058_08700	COG0563	adenylate kinase activity
NM058_08725	COG4824	toxin secretion phage lysis holin
NM058_08730	COG5632	N-Acetylmuramoyl-L-alanine amidase
NM058_08730	COG3409	Peptidoglycan-binding domain 1 protein
NM058_08740	COG2732	(Barnase) inhibitor
NM058_08755	COG4282	regulation of fungal-type cell wall biogenesis
NM058_08760	COG5444	nuclease activity
NM058_08770	COG0457	Tetratricopeptide repeat
NM058_08795	COG1733	regulation of RNA biosynthetic process
NM058_08800	COG2085	NADP oxidoreductase coenzyme F420-dependent
NM058_08805	COG1309	transcriptional regulator
NM058_08810	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_08835	COG1937	Protein conserved in bacteria
NM058_08850	COG0425	Belongs to the sulfur carrier protein TusA family
NM058_08850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NM058_08865	COG0425	Belongs to the sulfur carrier protein TusA family
NM058_08870	COG0730	response to heat
NM058_08875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NM058_08880	COG1522	sequence-specific DNA binding
NM058_08885	COG1522	sequence-specific DNA binding
NM058_08890	COG1335	isochorismatase
NM058_08895	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NM058_08900	COG2814	Major facilitator Superfamily
NM058_08905	COG2814	Major facilitator Superfamily
NM058_08940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NM058_08945	COG0398	Pfam SNARE associated Golgi protein
NM058_08950	COG3409	Peptidoglycan-binding domain 1 protein
NM058_08950	COG5632	N-Acetylmuramoyl-L-alanine amidase
NM058_08955	COG2755	lipolytic protein G-D-S-L family
NM058_08965	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NM058_08970	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NM058_08975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NM058_08980	COG1534	Rna-binding protein
NM058_08985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NM058_08990	COG1713	HD superfamily hydrolase involved in NAD metabolism
NM058_08995	COG0799	negative regulation of ribosome biogenesis
NM058_09000	COG2226	methyltransferase
NM058_09010	COG1555	photosystem II stabilization
NM058_09010	COG1596	polysaccharide export
NM058_09015	COG2131	deaminase
NM058_09035	COG1466	dna polymerase III delta subunit
NM058_09040	COG0268	Binds directly to 16S ribosomal RNA
NM058_09050	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM058_09060	COG0481	GTPase activity
NM058_09070	COG1420	regulation of RNA biosynthetic process
NM058_09090	COG2264	protein methyltransferase activity
NM058_09095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NM058_09100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NM058_09105	COG1283	sodium-dependent phosphate transmembrane transporter activity
NM058_09115	COG1610	YqeY-like protein
NM058_09120	COG1030	water channel activity
NM058_09125	COG4864	UPF0365 protein
NM058_09145	COG1702	phosphate starvation-inducible protein PhoH
NM058_09155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NM058_09160	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NM058_09165	COG0295	cytidine deaminase activity
NM058_09170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NM058_09180	COG1381	Involved in DNA repair and RecF pathway recombination
NM058_09185	COG0752	glycyl-tRNA synthetase alpha subunit
NM058_09195	COG0517	IMP dehydrogenase activity
NM058_09200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NM058_09205	COG1671	Belongs to the UPF0178 family
NM058_09210	COG0358	DNA primase activity
NM058_09215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NM058_09220	COG2010	Cytochrome c
NM058_09225	COG2384	SAM-dependent methyltransferase
NM058_09230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NM058_09235	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NM058_09245	COG0513	Belongs to the DEAD box helicase family
NM058_09250	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NM058_09265	COG0735	belongs to the Fur family
NM058_09270	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NM058_09275	COG4709	membrane
NM058_09285	COG1388	LysM domain
NM058_09290	COG5521	maltodextrose utilization protein MalA
NM058_09295	COG2839	Protein conserved in bacteria
NM058_09310	COG0768	penicillin binding
NM058_09315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NM058_09320	COG0573	inorganic phosphate transmembrane transporter activity
NM058_09325	COG0581	inorganic phosphate transmembrane transporter activity
NM058_09330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NM058_09340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NM058_09365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NM058_09385	COG1940	carbohydrate kinase activity
NM058_09395	COG2866	Carboxypeptidase
NM058_09405	COG0011	TIGRFAM Protein of
NM058_09415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM058_09425	COG1393	Belongs to the ArsC family
NM058_09435	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_09445	COG0598	Magnesium transport protein CorA
NM058_09450	COG0517	IMP dehydrogenase activity
NM058_09460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NM058_09470	COG4537	Required for transformation and DNA binding
NM058_09475	COG4970	Tfp pilus assembly protein FimT
NM058_09485	COG4940	Competence protein ComGF
NM058_09510	COG0681	Belongs to the peptidase S26 family
NM058_09520	COG1396	sequence-specific DNA binding
NM058_09535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NM058_09540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NM058_09545	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NM058_09555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NM058_09560	COG0095	Lipoate-protein ligase
NM058_09565	COG1321	iron dependent repressor
NM058_09570	COG1752	Esterase of the alpha-beta hydrolase superfamily
NM058_09590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NM058_09595	COG0006	proline dipeptidase activity
NM058_09600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NM058_09610	COG3854	ATPases associated with a variety of cellular activities
NM058_09655	COG0439	Biotin carboxylase
NM058_09660	COG1302	Protein conserved in bacteria
NM058_09665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NM058_09670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NM058_09680	COG1722	exodeoxyribonuclease VII activity
NM058_09685	COG0142	geranyltranstransferase activity
NM058_09700	COG1438	arginine binding
NM058_09705	COG0497	DNA recombination
NM058_09710	COG0750	zinc metalloprotease
NM058_09715	COG0745	RESPONSE REGULATOR receiver
NM058_09725	COG1902	pentaerythritol trinitrate reductase activity
NM058_09740	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM058_09745	COG0584	glycerophosphoryl diester phosphodiesterase
NM058_09755	COG1250	3-hydroxyacyl-CoA dehydrogenase
NM058_09775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NM058_09785	COG3829	transcription factor binding
NM058_09785	COG3290	protein histidine kinase activity
NM058_09795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NM058_09805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NM058_09810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NM058_09815	COG0022	dehydrogenase e1 component
NM058_09820	COG0508	dehydrogenase complex catalyzes the overall conversion of
NM058_09825	COG0789	Transcriptional regulator
NM058_09825	COG4978	Transcriptional regulator
NM058_09835	COG1597	lipid kinase activity
NM058_09845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM058_09850	COG0765	amino acid transport
NM058_09855	COG1126	abc transporter atp-binding protein
NM058_09860	COG4129	membrane
NM058_09865	COG1376	ErfK ybiS ycfS ynhG family protein
NM058_09875	COG0346	lactoylglutathione lyase activity
NM058_09880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NM058_09890	COG3361	conserved protein (COG2071)
NM058_09895	COG0706	membrane insertase activity
NM058_09905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NM058_09910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NM058_09915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NM058_09925	COG1234	tRNA 3'-trailer cleavage
NM058_09935	COG0596	Alpha beta hydrolase
NM058_09940	COG1902	pentaerythritol trinitrate reductase activity
NM058_09950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NM058_09960	COG0300	oxidoreductase activity
NM058_09970	COG1072	(Pantothenic acid kinase))
NM058_10010	COG0456	acetyltransferase
NM058_10015	COG2329	Antibiotic biosynthesis monooxygenase
NM058_10020	COG0456	acetyltransferase
NM058_10020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NM058_10025	COG4918	Iron-sulphur cluster biosynthesis
NM058_10035	COG1073	alpha beta
NM058_10045	COG0667	Aldo Keto reductase
NM058_10055	COG0494	nUDIX hydrolase
NM058_10060	COG1379	DNA repair
NM058_10065	COG1396	sequence-specific DNA binding
NM058_10070	COG0252	asparaginase activity
NM058_10080	COG1757	Na H antiporter
NM058_10085	COG0281	malic enzyme
NM058_10095	COG1300	Membrane
NM058_10100	COG0735	belongs to the Fur family
NM058_10110	COG4974	Belongs to the 'phage' integrase family
NM058_10115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NM058_10120	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NM058_10125	COG1686	Belongs to the peptidase S11 family
NM058_10130	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_10140	COG1191	sigma factor activity
NM058_10160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NM058_10175	COG0697	spore germination
NM058_10185	COG4086	secreted protein
NM058_10190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NM058_10205	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NM058_10210	COG0681	Belongs to the peptidase S26 family
NM058_10230	COG0307	riboflavin synthase, alpha
NM058_10235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NM058_10235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NM058_10240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NM058_10245	COG0456	acetyltransferase
NM058_10275	COG2715	membrane protein required for spore maturation
NM058_10280	COG0700	Nucleoside recognition
NM058_10290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_10300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NM058_10315	COG1595	DNA-templated transcription, initiation
NM058_10325	COG0710	3-dehydroquinate dehydratase activity
NM058_10330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NM058_10335	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NM058_10340	COG1141	Ferredoxin
NM058_10345	COG4955	Helix-turn-helix domain
NM058_10370	COG1408	metallophosphoesterase
NM058_10380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NM058_10385	COG0492	ferredoxin-NADP+ reductase activity
NM058_10390	COG2339	peptidase activity
NM058_10395	COG3409	Peptidoglycan-binding domain 1 protein
NM058_10395	COG3773	Cell wall hydrolase
NM058_10400	COG2959	enzyme of heme biosynthesis
NM058_10405	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NM058_10425	COG1304	FMN binding
NM058_10450	COG1160	GTP binding
NM058_10470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NM058_10475	COG0776	regulation of translation
NM058_10495	COG2226	methyltransferase
NM058_10500	COG0142	geranyltranstransferase activity
NM058_10505	COG0105	UTP biosynthetic process
NM058_10510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NM058_10515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NM058_10520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NM058_10525	COG4401	Chorismate mutase type I
NM058_10530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NM058_10535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NM058_10545	COG0135	phosphoribosylanthranilate isomerase activity
NM058_10555	COG0159	tryptophan synthase activity
NM058_10560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NM058_10575	COG0457	Tetratricopeptide repeat
NM058_10580	COG5582	Belongs to the UPF0302 family
NM058_10595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NM058_10605	COG4347	Protein of unknown function (DUF1405)
NM058_10615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM058_10620	COG1694	Mazg nucleotide pyrophosphohydrolase
NM058_10625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NM058_10630	COG1803	Methylglyoxal synthase
NM058_10655	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NM058_10660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NM058_10665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NM058_10685	COG0436	Aminotransferase
NM058_10690	COG0017	Asparaginyl-tRNA synthetase
NM058_10695	COG3935	DnaD domain protein
NM058_10700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NM058_10710	COG4499	WXG100 protein secretion system (Wss), protein YukC
NM058_10710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NM058_10750	COG0071	Belongs to the small heat shock protein (HSP20) family
NM058_10755	COG2190	(PTS) system
NM058_10765	COG3359	exonuclease
NM058_10780	COG4474	Belongs to the UPF0398 family
NM058_10795	COG0116	Belongs to the methyltransferase superfamily
NM058_10810	COG1199	ATP-dependent helicase activity
NM058_10815	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_10820	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NM058_10825	COG1609	Transcriptional regulator
NM058_10830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NM058_10835	COG0800	Aldolase
NM058_10845	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NM058_10850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NM058_10860	COG3424	synthase
NM058_10865	COG1755	Isoprenylcysteine carboxyl methyltransferase
NM058_10890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NM058_10900	COG0328	RNA-DNA hybrid ribonuclease activity
NM058_10910	COG0328	RNA-DNA hybrid ribonuclease activity
NM058_10930	COG1278	Cold shock
NM058_10940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NM058_10945	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NM058_10950	COG0386	Belongs to the glutathione peroxidase family
NM058_10960	COG1413	lyase activity
NM058_10965	COG0129	dihydroxy-acid dehydratase activity
NM058_10975	COG2136	Putative SAM-dependent methyltransferase
NM058_10975	COG2521	methyltransferase
NM058_10985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NM058_10995	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NM058_11000	COG0204	Acyl-transferase
NM058_11005	COG1272	protein, Hemolysin III
NM058_11010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NM058_11015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NM058_11025	COG1999	signal sequence binding
NM058_11030	COG2755	lipolytic protein G-D-S-L family
NM058_11035	COG4698	Protein conserved in bacteria
NM058_11050	COG1846	Transcriptional regulator
NM058_11055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NM058_11060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NM058_11065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NM058_11070	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
NM058_11075	COG4641	Protein conserved in bacteria
NM058_11120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NM058_11125	COG0456	acetyltransferase
NM058_11140	COG4479	Belongs to the UPF0346 family
NM058_11160	COG0671	phosphoesterase, PA-phosphatase related
NM058_11175	COG0813	purine-nucleoside phosphorylase activity
NM058_11180	COG1876	peptidase activity
NM058_11195	COG0793	Belongs to the peptidase S41A family
NM058_11195	COG3409	Peptidoglycan-binding domain 1 protein
NM058_11200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NM058_11210	COG0346	lactoylglutathione lyase activity
NM058_11225	COG1733	regulation of RNA biosynthetic process
NM058_11235	COG1942	4-Oxalocrotonate Tautomerase
NM058_11265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NM058_11270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NM058_11275	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_11285	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NM058_11290	COG1819	glycosyl
NM058_11295	COG0791	NLP P60 protein
NM058_11295	COG1388	LysM domain
NM058_11300	COG2032	superoxide dismutase activity
NM058_11305	COG0714	Associated with various cellular activities
NM058_11315	COG0567	Dehydrogenase, E1 component
NM058_11325	COG0385	Bile acid
NM058_11330	COG0733	neurotransmitter:sodium symporter activity
NM058_11335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NM058_11340	COG1657	PFAM Prenyltransferase squalene oxidase
NM058_11345	COG1012	belongs to the aldehyde dehydrogenase family
NM058_11360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NM058_11365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NM058_11375	COG0514	ATP-dependent DNA helicase (RecQ)
NM058_11380	COG1388	LysM domain
NM058_11380	COG3584	3D domain protein
NM058_11385	COG2197	response regulator
NM058_11390	COG4585	Histidine kinase
NM058_11395	COG3239	Fatty acid desaturase
NM058_11400	COG1619	proteins homologs of microcin C7 resistance protein MccF
NM058_11415	COG2322	membrane
NM058_11420	COG0741	lytic transglycosylase activity
NM058_11425	COG0640	Transcriptional regulator
NM058_11435	COG2378	regulation of single-species biofilm formation
NM058_11440	COG3708	Transcriptional regulator
NM058_11445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM058_11450	COG1309	transcriptional regulator
NM058_11455	COG0456	acetyltransferase
NM058_11460	COG0662	Cupin 2, conserved barrel domain protein
NM058_11460	COG2207	Transcriptional regulator
NM058_11465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NM058_11480	COG0577	efflux transmembrane transporter activity
NM058_11480	COG1136	(ABC) transporter
NM058_11490	COG1404	Belongs to the peptidase S8 family
NM058_11500	COG1404	Belongs to the peptidase S8 family
NM058_11580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NM058_11600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_11605	COG0463	Glycosyl transferase, family 2
NM058_11645	COG3655	Transcriptional regulator
NM058_11720	COG0726	polysaccharide deacetylase
NM058_11730	COG1231	oxidoreductase activity
NM058_11735	COG4282	regulation of fungal-type cell wall biogenesis
NM058_11755	COG3848	Pyruvate phosphate dikinase
NM058_11755	COG0574	Belongs to the PEP-utilizing enzyme family
NM058_11760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM058_11765	COG3397	chitin binding
NM058_11775	COG2367	Beta-lactamase
NM058_11780	COG0693	protein deglycase activity
NM058_11790	COG1388	LysM domain
NM058_11795	COG0697	spore germination
NM058_11805	COG3739	integral membrane protein
NM058_11845	COG0457	Tetratricopeptide repeat
NM058_11855	COG2140	Oxalate decarboxylase
NM058_11865	COG2135	peptidase activity
NM058_11890	COG3619	membrane
NM058_11895	COG4305	rare lipoprotein A
NM058_11900	COG2368	4-hydroxyphenylacetate
NM058_11905	COG0840	transmembrane signaling receptor activity
NM058_11905	COG5278	phosphoserine phosphatase activity
NM058_11925	COG1082	Xylose isomerase domain protein TIM barrel
NM058_11945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NM058_11960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM058_11970	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NM058_11990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NM058_11995	COG0583	DNA-binding transcription factor activity
NM058_12000	COG0067	glutamate synthase
NM058_12000	COG0069	glutamate synthase activity
NM058_12000	COG0070	glutamate synthase
NM058_12005	COG0493	'glutamate synthase
NM058_12015	COG0583	DNA-binding transcription factor activity
NM058_12020	COG0405	Gamma-glutamyltransferase
NM058_12025	COG0166	Belongs to the GPI family
NM058_12030	COG0582	viral genome integration into host DNA
NM058_12045	COG0534	Mate efflux family protein
NM058_12050	COG2017	converts alpha-aldose to the beta-anomer
NM058_12075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_12080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_12090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_12090	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NM058_12100	COG1649	PFAM Uncharacterised BCR, COG1649
NM058_12120	COG1960	acyl-CoA dehydrogenase activity
NM058_12135	COG0511	ligase activity, forming carbon-carbon bonds
NM058_12140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NM058_12150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NM058_12155	COG2404	hydrolase activity, acting on ester bonds
NM058_12160	COG0586	Pfam SNARE associated Golgi protein
NM058_12170	COG2246	polysaccharide biosynthetic process
NM058_12205	COG5520	Belongs to the glycosyl hydrolase 30 family
NM058_12220	COG1115	amino acid carrier protein
NM058_12235	COG0187	DNA topoisomerase II activity
NM058_12240	COG1832	CoA-binding protein
NM058_12245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NM058_12250	COG4841	protein insertion into membrane
NM058_12260	COG0824	Thioesterase
NM058_12280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_12285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NM058_12300	COG0071	Belongs to the small heat shock protein (HSP20) family
NM058_12310	COG4846	Membrane protein involved in cytochrome C biogenesis
NM058_12320	COG0785	Cytochrome C biogenesis protein
NM058_12330	COG3763	UPF0154 protein
NM058_12340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NM058_12345	COG4224	UPF0291 protein
NM058_12350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NM058_12355	COG1388	LysM domain
NM058_12360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NM058_12370	COG0346	lactoylglutathione lyase activity
NM058_12380	COG4195	phage-related replication protein
NM058_12410	COG0531	amino acid
NM058_12415	COG0697	spore germination
NM058_12420	COG2059	Chromate
NM058_12430	COG3832	glyoxalase III activity
NM058_12440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NM058_12490	COG0756	dUTP diphosphatase activity
NM058_12500	COG2814	Major facilitator Superfamily
NM058_12505	COG1525	nuclease
NM058_12515	COG1070	Carbohydrate kinase
NM058_12535	COG2211	Major facilitator Superfamily
NM058_12565	COG0135	phosphoribosylanthranilate isomerase activity
NM058_12605	COG1733	regulation of RNA biosynthetic process
NM058_12610	COG2249	NAD(P)H dehydrogenase (quinone) activity
NM058_12645	COG0174	glutamine synthetase
NM058_12650	COG0789	Transcriptional regulator
NM058_12660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NM058_12665	COG0464	growth
NM058_12670	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM058_12675	COG4112	unkown
NM058_12680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NM058_12685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NM058_12690	COG1780	Probably involved in ribonucleotide reductase function
NM058_12705	COG1923	regulation of RNA biosynthetic process
NM058_12735	COG1764	response to oxidative stress
NM058_12740	COG4195	phage-related replication protein
NM058_12755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM058_12765	COG3226	Transcriptional regulator
NM058_12805	COG4974	Belongs to the 'phage' integrase family
NM058_12810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NM058_12825	COG4550	Control of competence regulator ComK, YlbF/YmcA
NM058_12830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NM058_12835	COG0156	8-amino-7-oxononanoate synthase activity
NM058_12840	COG1063	alcohol dehydrogenase
NM058_12845	COG2359	stage V sporulation protein S
NM058_12855	COG1418	mRNA catabolic process
NM058_12860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NM058_12865	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NM058_12870	COG1546	Belongs to the CinA family
NM058_12870	COG1058	Belongs to the CinA family
NM058_12875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NM058_12895	COG0300	oxidoreductase activity
NM058_12900	COG0612	Peptidase, M16
NM058_12905	COG0612	Peptidase, M16
NM058_12910	COG2814	Major facilitator Superfamily
NM058_12915	COG2188	Transcriptional regulator
NM058_12920	COG1674	ftsk spoiiie
NM058_12920	COG4980	gas vesicle protein
NM058_12930	COG0740	serine-type endopeptidase activity
NM058_12935	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NM058_12950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NM058_12955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NM058_12960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NM058_12965	COG1873	PFAM PRC-barrel domain
NM058_12970	COG0612	Peptidase, M16
NM058_12980	COG1185	polyribonucleotide nucleotidyltransferase activity
NM058_12990	COG0196	riboflavin kinase activity
NM058_12995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NM058_13000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NM058_13005	COG1550	Protein conserved in bacteria
NM058_13015	COG1358	cellular component organization or biogenesis
NM058_13030	COG0779	Required for maturation of 30S ribosomal subunits
NM058_13035	COG2176	DNA-directed DNA polymerase activity
NM058_13040	COG0442	prolyl-tRNA aminoacylation
NM058_13045	COG0750	zinc metalloprotease
NM058_13055	COG4589	Belongs to the CDS family
NM058_13060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NM058_13065	COG0233	cytoplasmic translational termination
NM058_13070	COG0528	UMP kinase activity
NM058_13080	COG0052	Belongs to the universal ribosomal protein uS2 family
NM058_13090	COG1191	sigma factor activity
NM058_13095	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NM058_13100	COG1776	CheC inhibitor of MCP methylation
NM058_13105	COG0835	chemotaxis
NM058_13110	COG2198	Histidine kinase
NM058_13110	COG0643	Histidine kinase
NM058_13115	COG2201	protein-glutamate methylesterase activity
NM058_13120	COG0455	bacterial-type flagellum organization
NM058_13125	COG1419	protein localization to endoplasmic reticulum
NM058_13135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NM058_13140	COG1684	flagellar biosynthetic protein fliR
NM058_13145	COG1987	bacterial-type flagellum assembly
NM058_13150	COG1338	Plays a role in the flagellum-specific transport system
NM058_13155	COG3190	flagellar
NM058_13160	COG2201	protein-glutamate methylesterase activity
NM058_13165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NM058_13165	COG1776	CheC inhibitor of MCP methylation
NM058_13170	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NM058_13175	COG1580	Controls the rotational direction of flagella during chemotaxis
NM058_13180	COG1582	Flagellar protein (FlbD)
NM058_13185	COG4786	Flagellar basal body rod
NM058_13190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NM058_13195	COG3144	bacterial-type flagellum assembly
NM058_13200	COG3334	PFAM MgtE intracellular
NM058_13205	COG2882	bacterial-type flagellum organization
NM058_13210	COG1157	protein secretion by the type III secretion system
NM058_13215	COG1317	bacterial-type flagellum organization
NM058_13225	COG1766	The M ring may be actively involved in energy transduction
NM058_13230	COG1677	Flagellar hook-basal body complex protein FliE
NM058_13235	COG1558	bacterial-type flagellum-dependent cell motility
NM058_13240	COG1815	bacterial-type flagellum-dependent cell motility
NM058_13245	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NM058_13260	COG4974	Belongs to the 'phage' integrase family
NM058_13265	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NM058_13275	COG0758	DNA mediated transformation
NM058_13280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NM058_13290	COG2257	FlhB HrpN YscU SpaS Family
NM058_13300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NM058_13305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NM058_13310	COG0335	large ribosomal subunit rRNA binding
NM058_13315	COG0336	Belongs to the RNA methyltransferase TrmD family
NM058_13320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NM058_13330	COG1837	Belongs to the UPF0109 family
NM058_13335	COG0228	four-way junction DNA binding
NM058_13340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NM058_13345	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NM058_13355	COG0552	protein localization to endoplasmic reticulum
NM058_13360	COG1196	nuclear chromosome segregation
NM058_13365	COG0571	ribonuclease III activity
NM058_13375	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_13380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NM058_13385	COG0416	fatty acid biosynthetic process
NM058_13390	COG1349	DNA-binding transcription factor activity
NM058_13390	COG2050	protein possibly involved in aromatic compounds catabolism
NM058_13395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NM058_13400	COG1760	l-serine dehydratase
NM058_13405	COG1760	l-serine dehydratase
NM058_13410	COG1461	Dihydroxyacetone kinase
NM058_13415	COG1302	Protein conserved in bacteria
NM058_13420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NM058_13435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NM058_13440	COG1162	GTPase activity
NM058_13450	COG0631	protein serine/threonine phosphatase activity
NM058_13460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NM058_13460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NM058_13470	COG0242	peptide deformylase activity
NM058_13475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NM058_13480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NM058_13485	COG1758	RNA polymerase activity
NM058_13490	COG0194	GDP metabolic process
NM058_13505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NM058_13515	COG1648	precorrin-2 dehydrogenase activity
NM058_13535	COG2046	Belongs to the sulfate adenylyltransferase family
NM058_13540	COG0306	phosphate transporter
NM058_13545	COG0175	sulfate reduction
NM058_13550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NM058_13555	COG0284	orotidine-5'-phosphate decarboxylase activity
NM058_13560	COG0167	dihydroorotate dehydrogenase activity
NM058_13570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NM058_13575	COG0505	Belongs to the CarA family
NM058_13590	COG2233	PERMEase
NM058_13595	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NM058_13600	COG0564	pseudouridine synthase activity
NM058_13615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NM058_13620	COG3599	regulation of cell shape
NM058_13625	COG2302	S4 RNA-binding domain
NM058_13630	COG0762	integral membrane protein
NM058_13635	COG1799	cell septum assembly
NM058_13640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NM058_13645	COG1496	oxidoreductase activity
NM058_13650	COG1873	PFAM PRC-barrel domain
NM058_13655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NM058_13660	COG1119	ATPase activity
NM058_13665	COG1191	sigma factor activity
NM058_13670	COG1191	sigma factor activity
NM058_13690	COG0849	cell division
NM058_13695	COG3856	small basic protein
NM058_13705	COG3879	Bacterial protein of unknown function (DUF881)
NM058_13710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NM058_13715	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NM058_13740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NM058_13750	COG0768	penicillin binding
NM058_13755	COG4839	cell division protein FtsL
NM058_13760	COG0275	rRNA processing
NM058_13765	COG2001	Belongs to the MraZ family
NM058_13775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NM058_13780	COG0454	-acetyltransferase
NM058_13805	COG1323	Belongs to the UPF0348 family
NM058_13810	COG3480	Lon protease (S16) C-terminal proteolytic domain
NM058_13820	COG3314	Sporulation integral membrane protein YlbJ
NM058_13825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NM058_13830	COG0742	ribosomal rna small subunit methyltransferase
NM058_13835	COG4471	UPF0298 protein
NM058_13840	COG3679	Belongs to the UPF0342 family
NM058_13855	COG2340	Cysteine-rich secretory protein family
NM058_13860	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NM058_13870	COG3336	cytochrome c oxidase
NM058_13875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NM058_13880	COG1845	cytochrome c oxidase, subunit III
NM058_13890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NM058_13890	COG2010	Cytochrome c
NM058_13895	COG0109	protoheme IX farnesyltransferase activity
NM058_13905	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NM058_13915	COG4838	Belongs to the UPF0358 family
NM058_13920	COG2066	Belongs to the glutaminase family
NM058_13925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NM058_13940	COG4896	Protein conserved in bacteria
NM058_13950	COG1217	gtp-binding protein TYPA
NM058_13970	COG1595	DNA-templated transcription, initiation
NM058_13990	COG1959	2 iron, 2 sulfur cluster binding
NM058_13995	COG0657	acetylesterase activity
NM058_14010	COG0483	inositol monophosphate 1-phosphatase activity
NM058_14020	COG4493	Belongs to the UPF0637 family
NM058_14025	COG4476	Belongs to the UPF0223 family
NM058_14030	COG1982	Orn Lys Arg decarboxylase major
NM058_14045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_14050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NM058_14060	COG0022	dehydrogenase e1 component
NM058_14065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NM058_14070	COG0497	DNA recombination
NM058_14080	COG0242	peptide deformylase activity
NM058_14090	COG5503	Protein of unknown function (DUF1447)
NM058_14095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NM058_14100	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NM058_14105	COG0569	domain protein
NM058_14110	COG2105	PFAM AIG2 family protein
NM058_14110	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NM058_14115	COG3852	Histidine kinase
NM058_14120	COG2002	toxin-antitoxin pair type II binding
NM058_14140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NM058_14145	COG0488	(ABC) transporter
NM058_14155	COG0681	Belongs to the peptidase S26 family
NM058_14160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM058_14160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NM058_14160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM058_14165	COG1105	Belongs to the carbohydrate kinase PfkB family
NM058_14170	COG1349	DNA-binding transcription factor activity
NM058_14175	COG0577	efflux transmembrane transporter activity
NM058_14180	COG1136	(ABC) transporter
NM058_14185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NM058_14195	COG1132	(ABC) transporter
NM058_14200	COG1132	(ABC) transporter
NM058_14205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NM058_14210	COG0314	molybdopterin synthase activity
NM058_14215	COG1763	Mo-molybdopterin cofactor biosynthetic process
NM058_14220	COG0303	'Molybdopterin
NM058_14230	COG0746	molybdenum cofactor guanylyltransferase activity
NM058_14245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_14250	COG0450	alkyl hydroperoxide reductase
NM058_14255	COG0668	transmembrane transport
NM058_14270	COG2171	N-acyltransferase activity
NM058_14275	COG0716	FMN binding
NM058_14285	COG0716	FMN binding
NM058_14290	COG0583	DNA-binding transcription factor activity
NM058_14295	COG0517	IMP dehydrogenase activity
NM058_14305	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NM058_14320	COG2200	EAL domain
NM058_14325	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_14335	COG1376	ErfK ybiS ycfS ynhG family protein
NM058_14350	COG0784	Response regulator, receiver
NM058_14350	COG0835	chemotaxis
NM058_14360	COG0436	Aminotransferase
NM058_14365	COG4191	Histidine kinase
NM058_14375	COG2340	Cysteine-rich secretory protein family
NM058_14385	COG2084	Dehydrogenase
NM058_14390	COG0840	transmembrane signaling receptor activity
NM058_14400	COG1533	DNA photolyase activity
NM058_14410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NM058_14415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM058_14420	COG1263	PTS System
NM058_14420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM058_14420	COG2190	(PTS) system
NM058_14430	COG1609	Transcriptional regulator
NM058_14435	COG0006	proline dipeptidase activity
NM058_14445	COG2217	Heavy metal translocating P-type atpase
NM058_14450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_14455	COG2244	polysaccharide biosynthetic process
NM058_14470	COG4873	Protein conserved in bacteria
NM058_14480	COG3858	chitin binding
NM058_14485	COG1388	LysM domain
NM058_14490	COG4641	Protein conserved in bacteria
NM058_14490	COG1388	LysM domain
NM058_14495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NM058_14505	COG0720	synthase
NM058_14515	COG3949	Membrane
NM058_14520	COG0542	response to heat
NM058_14525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NM058_14535	COG1846	Transcriptional regulator
NM058_14540	COG3852	Histidine kinase
NM058_14555	COG3339	Conserved Protein
NM058_14560	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NM058_14565	COG0235	Class ii aldolase
NM058_14570	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NM058_14575	COG1850	ribulose-bisphosphate carboxylase activity
NM058_14580	COG0436	Aminotransferase
NM058_14585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NM058_14590	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NM058_14595	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NM058_14605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NM058_14610	COG5002	protein histidine kinase activity
NM058_14615	COG3594	Acyltransferase
NM058_14630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NM058_14635	COG0501	Belongs to the peptidase M48B family
NM058_14655	COG1191	sigma factor activity
NM058_14660	COG0861	Integral membrane protein TerC family
NM058_14665	COG0586	Pfam SNARE associated Golgi protein
NM058_14670	COG3300	MHYT domain
NM058_14670	COG5001	Diguanylate cyclase
NM058_14680	COG1793	dna ligase
NM058_14680	COG3285	dna ligase
NM058_14695	COG1408	metallophosphoesterase
NM058_14700	COG0726	polysaccharide deacetylase
NM058_14710	COG1846	Transcriptional regulator
NM058_14725	COG0789	Transcriptional regulator
NM058_14740	COG3212	peptidase
NM058_14745	COG3212	peptidase
NM058_14755	COG0745	RESPONSE REGULATOR receiver
NM058_14765	COG4721	ABC-type cobalt transport system, permease component
NM058_14780	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_14785	COG1404	Belongs to the peptidase S8 family
NM058_14790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NM058_14800	COG0590	tRNA wobble adenosine to inosine editing
NM058_14810	COG0457	Tetratricopeptide repeat
NM058_14810	COG0463	Glycosyl transferase, family 2
NM058_14815	COG1764	response to oxidative stress
NM058_14825	COG1764	response to oxidative stress
NM058_14830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NM058_14835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NM058_14845	COG2076	Multidrug Resistance protein
NM058_14850	COG2076	Multidrug Resistance protein
NM058_14855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM058_14860	COG2318	DinB family
NM058_14865	COG2323	membrane
NM058_14875	COG1017	nitric oxide dioxygenase activity
NM058_14875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NM058_14880	COG1607	acyl-coa hydrolase
NM058_14885	COG1834	amidinotransferase
NM058_14890	COG2706	6-phosphogluconolactonase activity
NM058_14915	COG4166	transmembrane transport
NM058_14920	COG0444	Belongs to the ABC transporter superfamily
NM058_14925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM058_14930	COG0601	transmembrane transport
NM058_14935	COG2362	D-Aminopeptidase
NM058_14945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NM058_14950	COG0463	Glycosyl transferase, family 2
NM058_14965	COG0346	lactoylglutathione lyase activity
NM058_14975	COG1392	Phosphate transport regulator
NM058_15045	COG3778	Protein conserved in bacteria
NM058_15050	COG3299	homolog of phage Mu protein gp47
NM058_15055	COG3628	GPW Gp25 family protein
NM058_15065	COG4193	domain, Protein
NM058_15075	COG3953	SLT domain
NM058_15075	COG5412	phage tail tape measure protein
NM058_15125	COG4653	Phage capsid family
NM058_15130	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NM058_15140	COG1783	phage Terminase large subunit
NM058_15150	COG1595	DNA-templated transcription, initiation
NM058_15170	COG1484	DNA-dependent DNA replication
NM058_15175	COG1522	sequence-specific DNA binding
NM058_15185	COG1396	sequence-specific DNA binding
NM058_15195	COG3546	catalase activity
NM058_15200	COG4195	phage-related replication protein
NM058_15210	COG5632	N-Acetylmuramoyl-L-alanine amidase
NM058_15210	COG3409	Peptidoglycan-binding domain 1 protein
NM058_15210	COG1388	LysM domain
NM058_15215	COG2350	Protein conserved in bacteria
NM058_15230	COG2318	DinB family
NM058_15235	COG0730	response to heat
NM058_15240	COG2721	sulfolactate sulfo-lyase activity
NM058_15245	COG0246	Mannitol dehydrogenase
NM058_15250	COG1609	Transcriptional regulator
NM058_15255	COG2271	Major facilitator Superfamily
NM058_15260	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_15265	COG1312	Catalyzes the dehydration of D-mannonate
NM058_15270	COG1063	alcohol dehydrogenase
NM058_15280	COG2211	Major facilitator Superfamily
NM058_15290	COG1252	NADH dehydrogenase
NM058_15305	COG0697	spore germination
NM058_15310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NM058_15315	COG0390	transport system, permease component
NM058_15320	COG1587	Uroporphyrinogen-III synthase
NM058_15330	COG1819	glycosyl
NM058_15335	COG2124	cytochrome p450
NM058_15370	COG2205	protein histidine kinase activity
NM058_15375	COG5504	Zn-dependent protease
NM058_15390	COG0726	polysaccharide deacetylase
NM058_15425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM058_15440	COG1482	cell wall glycoprotein biosynthetic process
NM058_15450	COG3711	transcriptional antiterminator
NM058_15450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM058_15460	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_15475	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NM058_15490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM058_15495	COG0626	cystathionine gamma-synthase activity
NM058_15505	COG2382	esterase
NM058_15510	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NM058_15515	COG2153	protein acetylation
NM058_15580	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NM058_15590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NM058_15595	COG2022	thiamine diphosphate biosynthetic process
NM058_15600	COG2104	thiamine diphosphate biosynthetic process
NM058_15605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NM058_15615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NM058_15625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NM058_15630	COG0564	pseudouridine synthase activity
NM058_15635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NM058_15640	COG2357	RelA SpoT domain protein
NM058_15650	COG4116	CYTH
NM058_15655	COG0741	lytic transglycosylase activity
NM058_15660	COG2346	COG2346, Truncated hemoglobins
NM058_15665	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NM058_15675	COG1164	Oligoendopeptidase f
NM058_15685	COG4862	establishment of competence for transformation
NM058_15700	COG1393	Belongs to the ArsC family
NM058_15705	COG0456	acetyltransferase
NM058_15715	COG4608	Belongs to the ABC transporter superfamily
NM058_15725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM058_15730	COG0601	transmembrane transport
NM058_15735	COG4166	transmembrane transport
NM058_15740	COG0180	Tryptophanyl-tRNA synthetase
NM058_15750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NM058_15755	COG0601	transmembrane transport
NM058_15780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NM058_15785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NM058_15800	COG1744	ABC transporter substrate-binding protein PnrA-like
NM058_15810	COG2267	carboxylic ester hydrolase activity
NM058_15825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NM058_15835	COG0505	Belongs to the CarA family
NM058_15850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NM058_15855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NM058_15860	COG2271	Major facilitator Superfamily
NM058_15865	COG0277	FAD linked oxidase domain protein
NM058_15880	COG1073	alpha beta
NM058_15885	COG0561	phosphatase activity
NM058_15905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM058_15915	COG3227	Zinc metalloprotease (Elastase)
NM058_15930	COG1695	Transcriptional regulator
NM058_15955	COG1666	GTP binding
NM058_15965	COG2153	protein acetylation
NM058_15980	COG4948	Mandelate Racemase Muconate Lactonizing
NM058_15995	COG2045	Belongs to the ComB family
NM058_16000	COG0175	sulfate reduction
NM058_16005	COG2046	Belongs to the sulfate adenylyltransferase family
NM058_16010	COG0529	Catalyzes the synthesis of activated sulfate
NM058_16015	COG2267	carboxylic ester hydrolase activity
NM058_16020	COG1357	PFAM Pentapeptide repeats (8 copies)
NM058_16030	COG1279	arginine transmembrane transporter activity
NM058_16035	COG2318	DinB family
NM058_16040	COG0673	inositol 2-dehydrogenase activity
NM058_16050	COG1917	Cupin 2, conserved barrel domain protein
NM058_16050	COG2207	Transcriptional regulator
NM058_16075	COG1404	Belongs to the peptidase S8 family
NM058_16085	COG0179	Fumarylacetoacetate (FAA) hydrolase
NM058_16090	COG5337	Spore coat protein CotH
NM058_16130	COG1403	HNH endonuclease
NM058_16135	COG0419	ATPase involved in DNA repair
NM058_16150	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NM058_16155	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NM058_16165	COG4533	DNA binding
NM058_16170	COG0477	Major facilitator Superfamily
NM058_16170	COG2814	Major facilitator Superfamily
NM058_16175	COG3180	Ammonia monooxygenase
NM058_16185	COG1846	Transcriptional regulator
NM058_16190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NM058_16195	COG0681	Belongs to the peptidase S26 family
NM058_16200	COG0398	Pfam SNARE associated Golgi protein
NM058_16215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NM058_16230	COG4903	ComK protein
NM058_16240	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_16250	COG0840	transmembrane signaling receptor activity
NM058_16260	COG0318	PFAM AMP-dependent synthetase and ligase
NM058_16270	COG0406	alpha-ribazole phosphatase activity
NM058_16275	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NM058_16285	COG0604	alcohol dehydrogenase
NM058_16295	COG1404	Belongs to the peptidase S8 family
NM058_16300	COG0501	Belongs to the peptidase M48B family
NM058_16310	COG0318	PFAM AMP-dependent synthetase and ligase
NM058_16320	COG0095	Lipoate-protein ligase
NM058_16345	COG1363	Peptidase, m42
NM058_16355	COG4377	Putative membrane peptidase family (DUF2324)
NM058_16360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NM058_16370	COG1309	transcriptional regulator
NM058_16375	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NM058_16380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NM058_16390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NM058_16395	COG2329	Antibiotic biosynthesis monooxygenase
NM058_16410	COG1473	amidohydrolase
NM058_16430	COG0537	adenosine 5'-monophosphoramidase activity
NM058_16450	COG4980	gas vesicle protein
NM058_16455	COG1846	Transcriptional regulator
NM058_16485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NM058_16505	COG0420	3'-5' exonuclease activity
NM058_16510	COG1668	transmembrane transport
NM058_16515	COG4152	abc transporter atp-binding protein
NM058_16525	COG1024	Enoyl-CoA hydratase
NM058_16535	COG0490	domain, Protein
NM058_16540	COG0475	glutathione-regulated potassium exporter activity
NM058_16550	COG0561	phosphatase activity
NM058_16555	COG4335	DNA alkylation repair
NM058_16560	COG3679	Belongs to the UPF0342 family
NM058_16565	COG4399	Belongs to the UPF0754 family
NM058_16570	COG0189	ligase activity
NM058_16595	COG0702	epimerase
NM058_16615	COG0589	response to stress
NM058_16620	COG1757	Na H antiporter
NM058_16625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NM058_16630	COG0726	polysaccharide deacetylase
NM058_16635	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NM058_16640	COG0668	transmembrane transport
NM058_16650	COG0584	glycerophosphoryl diester phosphodiesterase
NM058_16655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NM058_16660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NM058_16665	COG1253	flavin adenine dinucleotide binding
NM058_16675	COG0789	Transcriptional regulator
NM058_16680	COG1253	flavin adenine dinucleotide binding
NM058_16690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NM058_16695	COG0204	Acyl-transferase
NM058_16700	COG0667	Aldo Keto reductase
NM058_16705	COG1595	DNA-templated transcription, initiation
NM058_16720	COG0456	acetyltransferase
NM058_16725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM058_16730	COG0733	neurotransmitter:sodium symporter activity
NM058_16735	COG0531	amino acid
NM058_16760	COG1785	Belongs to the alkaline phosphatase family
NM058_16765	COG2719	SpoVR family
NM058_16775	COG1959	2 iron, 2 sulfur cluster binding
NM058_16780	COG0791	NLP P60 protein
NM058_16780	COG1388	LysM domain
NM058_16800	COG2197	response regulator
NM058_16805	COG2203	Gaf domain
NM058_16805	COG4585	Histidine kinase
NM058_16815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NM058_16820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NM058_16825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NM058_16830	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NM058_16835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NM058_16845	COG3153	acetyltransferase
NM058_16845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NM058_16850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NM058_16855	COG0517	IMP dehydrogenase activity
NM058_16865	COG0564	pseudouridine synthase activity
NM058_16870	COG3764	Sortase (surface protein transpeptidase)
NM058_16875	COG0737	Belongs to the 5'-nucleotidase family
NM058_16875	COG1525	nuclease
NM058_16875	COG4085	toxin activity
NM058_16880	COG5577	PFAM Coat F domain
NM058_16910	COG0456	acetyltransferase
NM058_16925	COG1464	Belongs to the NlpA lipoprotein family
NM058_16930	COG1278	Cold shock
NM058_16935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NM058_16940	COG1131	(ABC) transporter
NM058_16950	COG1725	Transcriptional regulator
NM058_16965	COG0655	NAD(P)H dehydrogenase (quinone) activity
NM058_16975	COG1566	PFAM secretion protein HlyD family protein
NM058_16980	COG1846	Transcriptional regulator
NM058_16985	COG2718	Belongs to the UPF0229 family
NM058_16990	COG2766	serine protein kinase
NM058_16995	COG1664	Polymer-forming cytoskeletal
NM058_17000	COG1664	Polymer-forming cytoskeletal
NM058_17020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NM058_17025	COG3382	B3 4 domain protein
NM058_17045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NM058_17060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NM058_17065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NM058_17070	COG1116	anion transmembrane transporter activity
NM058_17075	COG0753	catalase activity
NM058_17085	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NM058_17090	COG3340	Belongs to the peptidase S51 family
NM058_17095	COG5577	PFAM Coat F domain
NM058_17105	COG4326	sporulation control protein
NM058_17135	COG1819	glycosyl
NM058_17140	COG1082	Xylose isomerase domain protein TIM barrel
NM058_17145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NM058_17145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NM058_17145	COG3321	synthase
NM058_17155	COG1024	Enoyl-CoA hydratase
NM058_17160	COG1024	Enoyl-CoA hydratase
NM058_17175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_17175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17175	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17175	COG3321	synthase
NM058_17185	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17185	COG3321	synthase
NM058_17185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_17190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_17190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17190	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17190	COG3321	synthase
NM058_17195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_17195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17195	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17195	COG3321	synthase
NM058_17200	COG0300	oxidoreductase activity
NM058_17200	COG3321	synthase
NM058_17200	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17200	COG0318	PFAM AMP-dependent synthetase and ligase
NM058_17205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17205	COG4221	oxidoreductase activity
NM058_17205	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17205	COG3321	synthase
NM058_17210	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17210	COG4221	oxidoreductase activity
NM058_17210	COG3321	synthase
NM058_17215	COG0300	oxidoreductase activity
NM058_17215	COG0318	PFAM AMP-dependent synthetase and ligase
NM058_17215	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17215	COG3321	synthase
NM058_17220	COG4221	oxidoreductase activity
NM058_17220	COG3321	synthase
NM058_17220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17220	COG0300	oxidoreductase activity
NM058_17225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17225	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_17225	COG3321	synthase
NM058_17240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_17240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17240	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17240	COG3321	synthase
NM058_17245	COG4221	oxidoreductase activity
NM058_17245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17245	COG3321	synthase
NM058_17245	COG0300	oxidoreductase activity
NM058_17250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17250	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_17250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17250	COG3321	synthase
NM058_17255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17255	COG0300	oxidoreductase activity
NM058_17255	COG3321	synthase
NM058_17255	COG4221	oxidoreductase activity
NM058_17260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17260	COG0300	oxidoreductase activity
NM058_17260	COG3321	synthase
NM058_17260	COG4221	oxidoreductase activity
NM058_17265	COG4221	oxidoreductase activity
NM058_17265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17265	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17265	COG3321	synthase
NM058_17270	COG3321	synthase
NM058_17270	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_17270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NM058_17270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17275	COG0300	oxidoreductase activity
NM058_17275	COG3321	synthase
NM058_17275	COG4221	oxidoreductase activity
NM058_17275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM058_17290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NM058_17305	COG2226	methyltransferase
NM058_17310	COG0534	Mate efflux family protein
NM058_17435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NM058_17445	COG4129	membrane
NM058_17450	COG1132	(ABC) transporter
NM058_17455	COG3557	Belongs to the UPF0374 family
NM058_17470	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_17480	COG1194	a g-specific adenine glycosylase
NM058_17485	COG1988	membrane-bound metal-dependent
NM058_17495	COG0463	Glycosyl transferase, family 2
NM058_17500	COG0596	Alpha beta hydrolase
NM058_17505	COG5658	integral membrane protein
NM058_17535	COG2137	regulation of response to DNA damage stimulus
NM058_17540	COG1090	epimerase
NM058_17555	COG0778	Nitroreductase
NM058_17560	COG0384	phenazine biosynthesis protein PhzF
NM058_17570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM058_17575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM058_17585	COG1846	Transcriptional regulator
NM058_17590	COG2814	Major facilitator Superfamily
NM058_17595	COG2318	DinB family
NM058_17605	COG1131	(ABC) transporter
NM058_17625	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NM058_17630	COG1695	Transcriptional regulator
NM058_17645	COG1511	domain protein
NM058_17645	COG0842	Transport permease protein
NM058_17655	COG2197	response regulator
NM058_17670	COG1082	Xylose isomerase domain protein TIM barrel
NM058_17680	COG4977	sequence-specific DNA binding
NM058_17680	COG1917	Cupin 2, conserved barrel domain protein
NM058_17685	COG2514	catechol 2,3-dioxygenase activity
NM058_17690	COG2259	Doxx family
NM058_17700	COG1132	(ABC) transporter
NM058_17705	COG1263	PTS System
NM058_17705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM058_17715	COG1486	melibiose metabolic process
NM058_17720	COG4842	Belongs to the WXG100 family
NM058_17740	COG1742	UPF0060 membrane protein
NM058_17760	COG0508	dehydrogenase complex catalyzes the overall conversion of
NM058_17765	COG0022	dehydrogenase e1 component
NM058_17770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NM058_17780	COG4637	Psort location Cytoplasmic, score
NM058_17790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NM058_17800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NM058_17810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NM058_17815	COG0598	Magnesium transport protein CorA
NM058_17835	COG0535	radical SAM domain protein
NM058_17840	COG0668	transmembrane transport
NM058_17865	COG4980	gas vesicle protein
NM058_17870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NM058_17875	COG4840	Belongs to the UPF0435 family
NM058_17880	COG2814	Major facilitator Superfamily
NM058_17890	COG0737	Belongs to the 5'-nucleotidase family
NM058_17895	COG0778	Nitroreductase
NM058_17900	COG2188	Transcriptional regulator
NM058_17910	COG1263	PTS System
NM058_17910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM058_17935	COG1368	sulfuric ester hydrolase activity
NM058_17940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NM058_17940	COG1263	PTS System
NM058_17965	COG2258	MOSC domain
NM058_17975	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NM058_17980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NM058_17985	COG2851	Citrate transporter
NM058_17990	COG3181	Tripartite tricarboxylate transporter family receptor
NM058_17995	COG4565	transcriptional regulatory protein
NM058_18005	COG0471	metal ion transport
NM058_18010	COG3866	Pectate lyase
NM058_18025	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NM058_18030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM058_18035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM058_18045	COG2130	NADP-dependent
NM058_18050	COG0456	acetyltransferase
NM058_18070	COG0789	Transcriptional regulator
NM058_18090	COG0840	transmembrane signaling receptor activity
NM058_18100	COG0531	amino acid
NM058_18105	COG1011	Hydrolase
NM058_18110	COG2223	nitrite transmembrane transporter activity
NM058_18115	COG1442	glycosyl transferase family 8
NM058_18120	COG1216	Glycosyl transferase, family 2
NM058_18125	COG1442	glycosyl transferase family 8
NM058_18145	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NM058_18145	COG2124	cytochrome p450
NM058_18165	COG1846	Transcriptional regulator
NM058_18170	COG0697	spore germination
NM058_18175	COG0670	Belongs to the BI1 family
NM058_18180	COG5583	Uncharacterized small protein (DUF2292)
NM058_18185	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_18195	COG0346	lactoylglutathione lyase activity
NM058_18200	COG2329	Antibiotic biosynthesis monooxygenase
NM058_18205	COG2323	membrane
NM058_18225	COG1653	transport
NM058_18235	COG1874	Beta-galactosidase
NM058_18240	COG2755	lipolytic protein G-D-S-L family
NM058_18245	COG3401	FG-GAP repeat protein
NM058_18250	COG3401	FG-GAP repeat protein
NM058_18255	COG5578	integral membrane protein
NM058_18265	COG2755	lipolytic protein G-D-S-L family
NM058_18270	COG2207	Transcriptional regulator
NM058_18275	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NM058_18285	COG1175	transmembrane transport
NM058_18300	COG2972	Histidine kinase
NM058_18315	COG0454	-acetyltransferase
NM058_18335	COG0702	epimerase
NM058_18340	COG3631	Ketosteroid isomerase-related protein
NM058_18345	COG1309	transcriptional regulator
NM058_18355	COG0217	transcriptional regulatory protein
NM058_18375	COG3391	amine dehydrogenase activity
NM058_18430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NM058_18435	COG1597	lipid kinase activity
NM058_18450	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NM058_18455	COG0154	amidase activity
NM058_18460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NM058_18465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NM058_18470	COG1285	pathogenesis
NM058_18475	COG1785	Belongs to the alkaline phosphatase family
NM058_18480	COG1785	Belongs to the alkaline phosphatase family
NM058_18485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NM058_18515	COG3321	synthase
NM058_18515	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_18515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_18515	COG4221	oxidoreductase activity
NM058_18535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_18540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NM058_18540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_18550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_18580	COG1960	acyl-CoA dehydrogenase activity
NM058_18595	COG1250	3-hydroxyacyl-CoA dehydrogenase
NM058_18600	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NM058_18625	COG2814	Major facilitator Superfamily
NM058_18635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NM058_18655	COG4496	protein, YerC YecD
NM058_18660	COG1470	cell adhesion involved in biofilm formation
NM058_18680	COG1522	sequence-specific DNA binding
NM058_18685	COG0151	Belongs to the GarS family
NM058_18695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NM058_18700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NM058_18705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NM058_18710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NM058_18715	COG0047	phosphoribosylformylglycinamidine synthase activity
NM058_18720	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NM058_18725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NM058_18730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NM058_18750	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NM058_18765	COG2252	PERMEase
NM058_18780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NM058_18780	COG0519	Catalyzes the synthesis of GMP from XMP
NM058_18790	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NM058_18805	COG1113	amino acid transport
NM058_18835	COG0823	Involved in the tonB-independent uptake of proteins
NM058_18840	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NM058_18860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NM058_18880	COG1073	alpha beta
NM058_18890	COG0459	protein refolding
NM058_18900	COG1266	CAAX protease self-immunity
NM058_18920	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NM058_18925	COG0315	cyclic pyranopterin monophosphate synthase activity
NM058_18930	COG0488	(ABC) transporter
NM058_18935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NM058_18940	COG0456	acetyltransferase
NM058_18950	COG0802	atpase or kinase
NM058_18955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NM058_19000	COG4124	Belongs to the glycosyl hydrolase 26 family
NM058_19005	COG1482	cell wall glycoprotein biosynthetic process
NM058_19015	COG2188	Transcriptional regulator
NM058_19025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM058_19030	COG1447	Phosphotransferase system cellobiose-specific component IIA
NM058_19035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NM058_19040	COG2814	Major facilitator Superfamily
NM058_19045	COG1388	LysM domain
NM058_19050	COG1078	dGTPase activity
NM058_19055	COG0454	-acetyltransferase
NM058_19065	COG5646	InterPro IPR014922
NM058_19070	COG1785	Belongs to the alkaline phosphatase family
NM058_19080	COG1819	glycosyl
NM058_19085	COG3858	chitin binding
NM058_19085	COG1388	LysM domain
NM058_19090	COG1802	Transcriptional regulator
NM058_19095	COG0730	response to heat
NM058_19100	COG2814	Major facilitator Superfamily
NM058_19105	COG2814	Major facilitator Superfamily
NM058_19120	COG1396	sequence-specific DNA binding
NM058_19125	COG1846	Transcriptional regulator
NM058_19130	COG0778	Nitroreductase
NM058_19135	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_19145	COG2409	Drug exporters of the RND superfamily
NM058_19145	COG1033	growth of symbiont in host cell
NM058_19150	COG1846	Transcriptional regulator
NM058_19155	COG2318	DinB family
NM058_19160	COG1113	amino acid transport
NM058_19165	COG0488	(ABC) transporter
NM058_19175	COG1082	Xylose isomerase domain protein TIM barrel
NM058_19185	COG1609	Transcriptional regulator
NM058_19190	COG0673	inositol 2-dehydrogenase activity
NM058_19200	COG0456	acetyltransferase
NM058_19210	COG1309	transcriptional regulator
NM058_19220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM058_19225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_19230	COG2259	Doxx family
NM058_19235	COG0346	lactoylglutathione lyase activity
NM058_19240	COG0778	Nitroreductase
NM058_19250	COG0789	Transcriptional regulator
NM058_19250	COG4978	Transcriptional regulator
NM058_19255	COG1811	Na channel or pump
NM058_19260	COG2409	Drug exporters of the RND superfamily
NM058_19265	COG2197	response regulator
NM058_19270	COG4585	Histidine kinase
NM058_19285	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NM058_19295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NM058_19300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM058_19310	COG0789	Transcriptional regulator
NM058_19315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NM058_19320	COG0640	Transcriptional regulator
NM058_19325	COG0446	pyridine nucleotide-disulphide oxidoreductase
NM058_19335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM058_19340	COG1733	regulation of RNA biosynthetic process
NM058_19345	COG3545	Serine hydrolase
NM058_19350	COG2030	dehydratase
NM058_19355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM058_19365	COG1522	sequence-specific DNA binding
NM058_19370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NM058_19380	COG0583	DNA-binding transcription factor activity
NM058_19385	COG1114	Component of the transport system for branched-chain amino acids
NM058_19405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NM058_19430	COG1316	TRANSCRIPTIONal
NM058_19435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM058_19440	COG1309	transcriptional regulator
NM058_19455	COG2814	Major facilitator Superfamily
NM058_19460	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
NM058_19480	COG1329	Transcriptional regulator
NM058_19485	COG1278	Cold shock
NM058_19495	COG2807	transmembrane transport
NM058_19520	COG1476	TRANSCRIPTIONal
NM058_19540	COG0697	spore germination
NM058_19545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM058_19555	COG0697	spore germination
NM058_19560	COG0702	epimerase
NM058_19565	COG0789	Transcriptional regulator
NM058_19565	COG4978	Transcriptional regulator
NM058_19570	COG0431	NADPH-dependent FMN reductase
NM058_19575	COG2070	2-Nitropropane dioxygenase
NM058_19580	COG1846	Transcriptional regulator
NM058_19635	COG3091	SprT-like family
NM058_19645	COG2183	response to ionizing radiation
NM058_19650	COG2208	phosphoserine phosphatase activity
NM058_19655	COG1191	sigma factor activity
NM058_19660	COG2172	sigma factor antagonist activity
NM058_19665	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_19670	COG2208	phosphoserine phosphatase activity
NM058_19675	COG2172	sigma factor antagonist activity
NM058_19680	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_19685	COG1366	Belongs to the anti-sigma-factor antagonist family
NM058_19690	COG2337	Toxic component of a toxin-antitoxin (TA) module
NM058_19695	COG0864	Transcriptional regulator
NM058_19700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NM058_19710	COG0736	holo-[acyl-carrier-protein] synthase activity
NM058_19715	COG0705	Rhomboid family
NM058_19725	COG3402	PFAM membrane-flanked domain
NM058_19730	COG0513	Belongs to the DEAD box helicase family
NM058_19740	COG1181	Belongs to the D-alanine--D-alanine ligase family
NM058_19745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NM058_19765	COG1960	acyl-CoA dehydrogenase activity
NM058_19780	COG1131	(ABC) transporter
NM058_19790	COG0628	permease
NM058_19800	COG4565	transcriptional regulatory protein
NM058_19810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NM058_19820	COG2329	Antibiotic biosynthesis monooxygenase
NM058_19825	COG0662	Cupin 2, conserved barrel domain protein
NM058_19830	COG3729	General stress protein
NM058_19840	COG4876	unkown
NM058_19845	COG2261	transglycosylase associated protein
NM058_19880	COG1215	transferase activity, transferring glycosyl groups
NM058_19885	COG5298	Protein conserved in bacteria
NM058_19890	COG3706	GGDEF domain
NM058_19895	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NM058_19900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NM058_19900	COG0551	DNA topoisomerase type I activity
NM058_19905	COG1522	sequence-specific DNA binding
NM058_19910	COG2814	Major facilitator Superfamily
NM058_19920	COG3871	stress protein (general stress protein 26)
NM058_19925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM058_19935	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_19940	COG2226	methyltransferase
NM058_19955	COG4989	oxidoreductase activity
NM058_19965	COG2329	Antibiotic biosynthesis monooxygenase
NM058_19975	COG2755	lipolytic protein G-D-S-L family
NM058_19980	COG1414	Transcriptional regulator
NM058_19985	COG1984	allophanate hydrolase subunit 2
NM058_19990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NM058_19995	COG4336	lyase activity
NM058_20005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NM058_20010	COG0561	phosphatase activity
NM058_20020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NM058_20025	COG0412	Dienelactone hydrolase
NM058_20030	COG0473	3-isopropylmalate dehydrogenase activity
NM058_20040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NM058_20065	COG4549	nuclear export factor GLE1
NM058_20070	COG1028	Short-chain dehydrogenase reductase Sdr
NM058_20085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NM058_20090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM058_20095	COG0640	Transcriptional regulator
NM058_20100	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NM058_20105	COG0778	Nitroreductase
NM058_20110	COG1309	transcriptional regulator
NM058_20115	COG2814	Major facilitator Superfamily
NM058_20120	COG4607	ABC-type enterochelin transport system periplasmic component
NM058_20125	COG4604	ABC transporter, ATP-binding protein
NM058_20130	COG4605	iron ion homeostasis
NM058_20135	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM058_20155	COG0457	Tetratricopeptide repeat
NM058_20160	COG3850	Histidine kinase
NM058_20160	COG5002	protein histidine kinase activity
NM058_20175	COG1136	(ABC) transporter
NM058_20200	COG5434	Belongs to the glycosyl hydrolase 28 family
NM058_20205	COG3104	oligopeptide transport
NM058_20225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NM058_20235	COG0583	DNA-binding transcription factor activity
NM058_20240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM058_20245	COG0765	amino acid transport
NM058_20250	COG1126	abc transporter atp-binding protein
NM058_20255	COG2364	Membrane
NM058_20265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NM058_20270	COG0697	spore germination
NM058_20295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_20300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_20320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_20325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_20330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_20335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_20340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NM058_20345	COG1733	regulation of RNA biosynthetic process
NM058_20350	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NM058_20355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NM058_20360	COG3290	protein histidine kinase activity
NM058_20360	COG0840	transmembrane signaling receptor activity
NM058_20365	COG3209	COG3209 Rhs family protein
NM058_20375	COG2723	6-phospho-beta-galactosidase activity
NM058_20390	COG1846	Transcriptional regulator
NM058_20410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NM058_20415	COG0765	amino acid transport
NM058_20420	COG0523	cobalamin synthesis protein
NM058_20430	COG1376	ErfK ybiS ycfS ynhG family protein
NM058_20450	COG0243	molybdopterin cofactor binding
NM058_20460	COG2146	nitrite reductase [NAD(P)H] activity
NM058_20470	COG0492	ferredoxin-NADP+ reductase activity
NM058_20480	COG0701	Predicted permease
NM058_20485	COG3689	TIGRFAM TIGR03943 family protein
NM058_20490	COG2508	Transcriptional regulator
NM058_20505	COG0506	proline dehydrogenase activity
NM058_20510	COG3541	Predicted nucleotidyltransferase
NM058_20515	COG3458	cephalosporin-C deacetylase activity
NM058_20520	COG0583	DNA-binding transcription factor activity
NM058_20525	COG2226	methyltransferase
NM058_20530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NM058_20540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NM058_20550	COG1113	amino acid transport
NM058_20555	COG3403	YqcI/YcgG family
NM058_20560	COG1280	lysine exporter protein (LysE YggA)
NM058_20565	COG1846	Transcriptional regulator
NM058_20570	COG2814	Major facilitator Superfamily
NM058_20585	COG0366	Alpha amylase catalytic
NM058_20595	COG1288	antiporter activity
NM058_20600	COG1473	amidohydrolase
NM058_20605	COG2113	Glycine betaine
NM058_20610	COG4176	ABC-type proline glycine betaine transport system permease component
NM058_20615	COG4175	Glycine betaine
NM058_20615	COG0517	IMP dehydrogenase activity
NM058_20620	COG0640	Transcriptional regulator
NM058_20625	COG2814	Major facilitator Superfamily
NM058_20630	COG0477	Major facilitator Superfamily
NM058_20635	COG3853	Toxic anion resistance protein (TelA)
NM058_20645	COG0861	Integral membrane protein TerC family
NM058_20650	COG2310	stress, protein
NM058_20655	COG2310	stress, protein
NM058_20660	COG2310	stress, protein
NM058_20670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NM058_20680	COG0803	Belongs to the bacterial solute-binding protein 9 family
NM058_20685	COG0366	Alpha amylase catalytic
NM058_20695	COG0457	Tetratricopeptide repeat
NM058_20705	COG1595	DNA-templated transcription, initiation
NM058_20725	COG0667	Aldo Keto reductase
NM058_20730	COG1668	transmembrane transport
NM058_20735	COG4555	ABC transporter
NM058_20740	COG3279	Response regulator of the LytR AlgR family
NM058_20745	COG3290	protein histidine kinase activity
NM058_20750	COG1405	negative regulation of cell septum assembly
NM058_20750	COG3012	SEC-C Motif Domain Protein
NM058_20755	COG1714	RDD family
NM058_20760	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NM058_20770	COG1309	transcriptional regulator
NM058_20775	COG0477	Major facilitator Superfamily
NM058_20780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NM058_20785	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NM058_20790	COG0805	protein transport
NM058_20795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NM058_20800	COG3540	Alkaline phosphatase
NM058_20810	COG2304	oxidoreductase activity
NM058_20815	COG3773	Cell wall hydrolase
NM058_20840	COG1131	(ABC) transporter
NM058_20845	COG2205	protein histidine kinase activity
NM058_20850	COG0745	RESPONSE REGULATOR receiver
NM058_20865	COG3173	Aminoglycoside phosphotransferase
NM058_20875	COG2186	Transcriptional regulator
NM058_20885	COG2271	Major facilitator Superfamily
NM058_20890	COG1012	belongs to the aldehyde dehydrogenase family
NM058_20895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NM058_20910	COG2066	Belongs to the glutaminase family
NM058_20915	COG1115	amino acid carrier protein
NM058_20925	COG0833	amino acid
NM058_20930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NM058_20940	COG2188	Transcriptional regulator
NM058_20955	COG1301	dicarboxylic acid transport
NM058_20965	COG2207	Transcriptional regulator
NM058_20970	COG2312	Erythromycin esterase
NM058_20980	COG0688	phosphatidylethanolamine metabolic process
NM058_20985	COG0586	Pfam SNARE associated Golgi protein
NM058_20990	COG1183	phosphatidylcholine synthase activity
NM058_20995	COG0596	Alpha beta hydrolase
NM058_21005	COG3591	Belongs to the peptidase S1B family
NM058_21010	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NM058_21015	COG2207	Transcriptional regulator
NM058_21015	COG1917	Cupin 2, conserved barrel domain protein
NM058_21020	COG0697	spore germination
NM058_21035	COG2271	Major facilitator Superfamily
NM058_21040	COG1846	Transcriptional regulator
NM058_21040	COG0456	acetyltransferase
NM058_21055	COG0584	glycerophosphoryl diester phosphodiesterase
NM058_21060	COG1283	sodium-dependent phosphate transmembrane transporter activity
NM058_21080	COG2602	Beta-lactamase
NM058_21095	COG1113	amino acid transport
NM058_21110	COG0515	serine threonine protein kinase
NM058_21120	COG0642	Histidine kinase
NM058_21125	COG0745	RESPONSE REGULATOR receiver
NM058_21135	COG0789	Transcriptional regulator
NM058_21145	COG1413	lyase activity
NM058_21150	COG2814	Major facilitator Superfamily
NM058_21155	COG0640	Transcriptional regulator
NM058_21160	COG5609	conserved protein (DUF2294)
NM058_21170	COG0288	reversible hydration of carbon dioxide
NM058_21180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NM058_21195	COG4856	YbbR-like protein
NM058_21200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NM058_21205	COG5662	AntiSigma factor
NM058_21210	COG1595	DNA-templated transcription, initiation
NM058_21240	COG1683	Conserved Protein
NM058_21245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NM058_21250	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NM058_21255	COG1737	Transcriptional regulator
NM058_21265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NM058_21280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NM058_21280	COG2207	Transcriptional regulator
NM058_21305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NM058_21310	COG2819	hydrolase of the alpha beta superfamily
NM058_21315	COG0385	Bile acid
NM058_21325	COG1063	alcohol dehydrogenase
NM058_21335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NM058_21340	COG0738	Major facilitator superfamily
NM058_21420	COG0726	polysaccharide deacetylase
NM058_21425	COG2194	sulfuric ester hydrolase activity
NM058_21435	COG0489	protein tyrosine kinase activity
NM058_21440	COG0860	N-Acetylmuramoyl-L-alanine amidase
NM058_21450	COG2226	methyltransferase
NM058_21455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NM058_21470	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NM058_21475	COG1122	ATPase activity
NM058_21480	COG1122	ATPase activity
NM058_21490	COG0203	ribosomal protein L17
NM058_21495	COG0202	RNA polymerase activity
NM058_21500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NM058_21505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NM058_21510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NM058_21520	COG0024	Methionine aminopeptidase
NM058_21525	COG0563	adenylate kinase activity
NM058_21530	COG0201	protein transport
NM058_21535	COG0200	Binds to the 23S rRNA
NM058_21550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NM058_21555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NM058_21560	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NM058_21570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NM058_21580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NM058_21585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NM058_21595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NM058_21615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NM058_21630	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NM058_21645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NM058_21650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NM058_21655	COG0049	tRNA binding
NM058_21660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NM058_21665	COG1358	cellular component organization or biogenesis
NM058_21675	COG0085	RNA polymerase activity
NM058_21690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NM058_21695	COG0081	regulation of translation
NM058_21705	COG0250	Participates in transcription elongation, termination and antitermination
NM058_21710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NM058_21720	COG1595	DNA-templated transcription, initiation
NM058_21735	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NM058_21740	COG0215	cysteine-tRNA ligase activity
NM058_21750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NM058_21755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NM058_21760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NM058_21765	COG4956	integral membrane protein (PIN domain superfamily)
NM058_21770	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NM058_21785	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NM058_21790	COG3880	PFAM UvrB UvrC protein
NM058_21795	COG4463	regulation of RNA biosynthetic process