locus-tag	class	description
AN935_00005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_00015	COG0516	GMP reductase activity
AN935_00015	COG0517	IMP dehydrogenase activity
AN935_00020	COG1686	Belongs to the peptidase S11 family
AN935_00030	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AN935_00035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AN935_00045	COG1428	Deoxynucleoside kinase
AN935_00050	COG1428	Deoxynucleoside kinase
AN935_00055	COG1388	LysM domain
AN935_00055	COG3858	chitin binding
AN935_00060	COG1335	isochorismatase
AN935_00065	COG0590	tRNA wobble adenosine to inosine editing
AN935_00080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AN935_00085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AN935_00090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AN935_00110	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AN935_00115	COG3853	Toxic anion resistance protein (TelA)
AN935_00120	COG1982	Orn Lys Arg decarboxylase major
AN935_00125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AN935_00130	COG3870	Protein conserved in bacteria
AN935_00135	COG1728	Protein conserved in bacteria
AN935_00140	COG0470	DNA polymerase III
AN935_00145	COG1774	PSP1 C-terminal conserved region
AN935_00150	COG4467	Involved in initiation control of chromosome replication
AN935_00155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AN935_00160	COG2827	Endonuclease containing a URI domain
AN935_00165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AN935_00170	COG2002	toxin-antitoxin pair type II binding
AN935_00175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_00175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_00180	COG0084	hydrolase, TatD family'
AN935_00185	COG3584	3D domain protein
AN935_00185	COG3583	domain protein
AN935_00190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AN935_00195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AN935_00205	COG4466	Protein conserved in bacteria
AN935_00215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AN935_00220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN935_00225	COG0251	oxidation-reduction process
AN935_00230	COG2088	sporulation resulting in formation of a cellular spore
AN935_00240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AN935_00245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN935_00250	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AN935_00255	COG0193	aminoacyl-tRNA hydrolase activity
AN935_00265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AN935_00270	COG2002	toxin-antitoxin pair type II binding
AN935_00275	COG2244	polysaccharide biosynthetic process
AN935_00280	COG3956	TIGRFAM MazG family protein
AN935_00285	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AN935_00300	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AN935_00305	COG1098	S1 RNA binding domain
AN935_00320	COG2208	phosphoserine phosphatase activity
AN935_00325	COG2304	oxidoreductase activity
AN935_00330	COG0515	serine threonine protein kinase
AN935_00335	COG0037	tRNA processing
AN935_00340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AN935_00345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN935_00350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AN935_00355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AN935_00360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN935_00365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN935_00370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN935_00375	COG0512	Glutamine amidotransferase of anthranilate synthase
AN935_00380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN935_00385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AN935_00390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AN935_00395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN935_00400	COG1396	sequence-specific DNA binding
AN935_00405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN935_00410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AN935_00420	COG4463	regulation of RNA biosynthetic process
AN935_00425	COG3880	PFAM UvrB UvrC protein
AN935_00430	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AN935_00435	COG0542	response to heat
AN935_00440	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AN935_00445	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AN935_00450	COG4956	integral membrane protein (PIN domain superfamily)
AN935_00455	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AN935_00460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AN935_00465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN935_00475	COG1045	serine acetyltransferase
AN935_00480	COG0215	cysteine-tRNA ligase activity
AN935_00485	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AN935_00490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN935_00495	COG3688	RNA-binding protein containing a PIN domain
AN935_00500	COG1595	DNA-templated transcription, initiation
AN935_00510	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN935_00515	COG0250	Participates in transcription elongation, termination and antitermination
AN935_00525	COG0081	regulation of translation
AN935_00530	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AN935_00540	COG2813	Specifically methylates the guanine in position
AN935_00545	COG0085	RNA polymerase activity
AN935_00550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AN935_00555	COG1358	cellular component organization or biogenesis
AN935_00560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AN935_00565	COG0049	tRNA binding
AN935_00570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AN935_00575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AN935_00580	COG0596	Alpha beta hydrolase
AN935_00590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AN935_00605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AN935_00625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AN935_00635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AN935_00640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AN935_00650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AN935_00660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AN935_00665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AN935_00670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AN935_00685	COG0200	Binds to the 23S rRNA
AN935_00690	COG0201	protein transport
AN935_00695	COG0563	adenylate kinase activity
AN935_00700	COG0024	Methionine aminopeptidase
AN935_00705	COG2163	COG2163 Ribosomal protein L14E L6E L27E
AN935_00715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AN935_00720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AN935_00725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AN935_00730	COG0202	RNA polymerase activity
AN935_00735	COG0203	ribosomal protein L17
AN935_00740	COG1122	ATPase activity
AN935_00745	COG1122	ATPase activity
AN935_00750	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AN935_00755	COG0101	tRNA pseudouridine synthase activity
AN935_00760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AN935_00765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AN935_00770	COG2226	methyltransferase
AN935_00780	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_00785	COG0489	protein tyrosine kinase activity
AN935_00795	COG2194	sulfuric ester hydrolase activity
AN935_00800	COG0726	polysaccharide deacetylase
AN935_00805	COG0738	Major facilitator superfamily
AN935_00810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN935_00820	COG1063	alcohol dehydrogenase
AN935_00825	COG0659	secondary active sulfate transmembrane transporter activity
AN935_00830	COG0385	Bile acid
AN935_00835	COG2819	hydrolase of the alpha beta superfamily
AN935_00840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_00845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_00850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_00855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_00855	COG2207	Transcriptional regulator
AN935_00860	COG3876	Protein conserved in bacteria
AN935_00865	COG1472	Belongs to the glycosyl hydrolase 3 family
AN935_00870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN935_00875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_00875	COG1263	PTS System
AN935_00880	COG1737	Transcriptional regulator
AN935_00885	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AN935_00890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_00895	COG1683	Conserved Protein
AN935_00910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_00940	COG1595	DNA-templated transcription, initiation
AN935_00945	COG5662	AntiSigma factor
AN935_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AN935_00955	COG4856	YbbR-like protein
AN935_00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN935_00970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN935_00975	COG3002	Belongs to the UPF0753 family
AN935_00980	COG0288	reversible hydration of carbon dioxide
AN935_00990	COG5609	conserved protein (DUF2294)
AN935_00995	COG0640	Transcriptional regulator
AN935_01000	COG2814	Major facilitator Superfamily
AN935_01005	COG1413	lyase activity
AN935_01015	COG0789	Transcriptional regulator
AN935_01020	COG0596	Alpha beta hydrolase
AN935_01025	COG0745	RESPONSE REGULATOR receiver
AN935_01030	COG0642	Histidine kinase
AN935_01040	COG0515	serine threonine protein kinase
AN935_01055	COG1113	amino acid transport
AN935_01070	COG2602	Beta-lactamase
AN935_01075	COG2124	cytochrome p450
AN935_01085	COG0531	amino acid
AN935_01090	COG1283	sodium-dependent phosphate transmembrane transporter activity
AN935_01095	COG0584	glycerophosphoryl diester phosphodiesterase
AN935_01100	COG2271	Major facilitator Superfamily
AN935_01110	COG0456	acetyltransferase
AN935_01110	COG1846	Transcriptional regulator
AN935_01115	COG2271	Major facilitator Superfamily
AN935_01130	COG0697	spore germination
AN935_01135	COG1917	Cupin 2, conserved barrel domain protein
AN935_01135	COG2207	Transcriptional regulator
AN935_01140	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AN935_01145	COG3591	Belongs to the peptidase S1B family
AN935_01155	COG0596	Alpha beta hydrolase
AN935_01160	COG1183	phosphatidylcholine synthase activity
AN935_01165	COG0586	Pfam SNARE associated Golgi protein
AN935_01170	COG0688	phosphatidylethanolamine metabolic process
AN935_01180	COG2312	Erythromycin esterase
AN935_01185	COG2207	Transcriptional regulator
AN935_01190	COG1054	Belongs to the UPF0176 family
AN935_01195	COG1301	dicarboxylic acid transport
AN935_01200	COG2190	(PTS) system
AN935_01200	COG1263	PTS System
AN935_01200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_01205	COG0363	glucosamine-6-phosphate deaminase activity
AN935_01210	COG2188	Transcriptional regulator
AN935_01220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN935_01225	COG0833	amino acid
AN935_01230	COG2040	homocysteine
AN935_01240	COG1115	amino acid carrier protein
AN935_01245	COG2066	Belongs to the glutaminase family
AN935_01250	COG4191	Histidine kinase
AN935_01255	COG0784	Response regulator, receiver
AN935_01260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN935_01265	COG1012	belongs to the aldehyde dehydrogenase family
AN935_01270	COG2271	Major facilitator Superfamily
AN935_01275	COG4948	Mandelate Racemase Muconate Lactonizing
AN935_01280	COG2186	Transcriptional regulator
AN935_01285	COG2721	sulfolactate sulfo-lyase activity
AN935_01290	COG3173	Aminoglycoside phosphotransferase
AN935_01300	COG0697	spore germination
AN935_01305	COG0745	RESPONSE REGULATOR receiver
AN935_01310	COG2205	protein histidine kinase activity
AN935_01315	COG1131	(ABC) transporter
AN935_01335	COG3773	Cell wall hydrolase
AN935_01340	COG2304	oxidoreductase activity
AN935_01350	COG3540	Alkaline phosphatase
AN935_01355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN935_01360	COG0805	protein transport
AN935_01365	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AN935_01370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN935_01375	COG0477	Major facilitator Superfamily
AN935_01380	COG1309	transcriptional regulator
AN935_01385	COG0252	asparaginase activity
AN935_01390	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AN935_01395	COG1714	RDD family
AN935_01400	COG1405	negative regulation of cell septum assembly
AN935_01400	COG3012	SEC-C Motif Domain Protein
AN935_01405	COG3290	protein histidine kinase activity
AN935_01410	COG3279	Response regulator of the LytR AlgR family
AN935_01415	COG4555	ABC transporter
AN935_01420	COG1668	transmembrane transport
AN935_01425	COG0667	Aldo Keto reductase
AN935_01435	COG1595	DNA-templated transcription, initiation
AN935_01440	COG1595	DNA-templated transcription, initiation
AN935_01450	COG0457	Tetratricopeptide repeat
AN935_01455	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_01460	COG0366	Alpha amylase catalytic
AN935_01465	COG0803	Belongs to the bacterial solute-binding protein 9 family
AN935_01470	COG1121	(ABC) transporter
AN935_01475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN935_01480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_01485	COG2310	stress, protein
AN935_01490	COG2310	stress, protein
AN935_01495	COG2310	stress, protein
AN935_01500	COG0861	Integral membrane protein TerC family
AN935_01510	COG3853	Toxic anion resistance protein (TelA)
AN935_01515	COG0477	Major facilitator Superfamily
AN935_01520	COG2814	Major facilitator Superfamily
AN935_01525	COG0640	Transcriptional regulator
AN935_01530	COG0517	IMP dehydrogenase activity
AN935_01530	COG4175	Glycine betaine
AN935_01535	COG4176	ABC-type proline glycine betaine transport system permease component
AN935_01540	COG2113	Glycine betaine
AN935_01545	COG1473	amidohydrolase
AN935_01550	COG1288	antiporter activity
AN935_01565	COG0366	Alpha amylase catalytic
AN935_01570	COG0039	L-malate dehydrogenase activity
AN935_01575	COG1620	l-lactate permease
AN935_01580	COG2814	Major facilitator Superfamily
AN935_01585	COG1846	Transcriptional regulator
AN935_01590	COG1280	lysine exporter protein (LysE YggA)
AN935_01595	COG3403	YqcI/YcgG family
AN935_01600	COG1113	amino acid transport
AN935_01605	COG3665	Urea carboxylase-associated protein
AN935_01610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AN935_01615	COG1660	Displays ATPase and GTPase activities
AN935_01620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AN935_01625	COG2226	methyltransferase
AN935_01630	COG0583	DNA-binding transcription factor activity
AN935_01635	COG3458	cephalosporin-C deacetylase activity
AN935_01640	COG3541	Predicted nucleotidyltransferase
AN935_01645	COG0506	proline dehydrogenase activity
AN935_01650	COG1012	belongs to the aldehyde dehydrogenase family
AN935_01655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_01660	COG2508	Transcriptional regulator
AN935_01665	COG3689	TIGRFAM TIGR03943 family protein
AN935_01670	COG0701	Predicted permease
AN935_01680	COG0492	ferredoxin-NADP+ reductase activity
AN935_01685	COG1587	Uroporphyrinogen-III synthase
AN935_01685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN935_01690	COG2146	nitrite reductase [NAD(P)H] activity
AN935_01695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN935_01700	COG0243	molybdopterin cofactor binding
AN935_01705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN935_01710	COG2223	nitrite transmembrane transporter activity
AN935_01715	COG1469	GTP cyclohydrolase I activity
AN935_01720	COG1376	ErfK ybiS ycfS ynhG family protein
AN935_01730	COG0523	cobalamin synthesis protein
AN935_01735	COG0765	amino acid transport
AN935_01740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_01745	COG1714	RDD family
AN935_01755	COG1846	Transcriptional regulator
AN935_01765	COG3842	ATPase activity
AN935_01770	COG2723	6-phospho-beta-galactosidase activity
AN935_01780	COG3209	COG3209 Rhs family protein
AN935_01785	COG0840	transmembrane signaling receptor activity
AN935_01785	COG3290	protein histidine kinase activity
AN935_01790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AN935_01795	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AN935_01800	COG1733	regulation of RNA biosynthetic process
AN935_01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_01815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_01820	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AN935_01825	COG2814	Major facilitator Superfamily
AN935_01835	COG0697	spore germination
AN935_01840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_01850	COG2364	Membrane
AN935_01855	COG1126	abc transporter atp-binding protein
AN935_01860	COG0765	amino acid transport
AN935_01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_01870	COG0583	DNA-binding transcription factor activity
AN935_01875	COG0163	prenyltransferase activity
AN935_01880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AN935_01895	COG0596	Alpha beta hydrolase
AN935_01900	COG3104	oligopeptide transport
AN935_01905	COG5434	Belongs to the glycosyl hydrolase 28 family
AN935_01915	COG0697	spore germination
AN935_01925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AN935_01930	COG1136	(ABC) transporter
AN935_01935	COG0577	efflux transmembrane transporter activity
AN935_01940	COG0745	RESPONSE REGULATOR receiver
AN935_01945	COG3850	Histidine kinase
AN935_01945	COG5002	protein histidine kinase activity
AN935_01950	COG0457	Tetratricopeptide repeat
AN935_01965	COG0527	aspartate kinase activity
AN935_01970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_01975	COG4605	iron ion homeostasis
AN935_01980	COG4604	ABC transporter, ATP-binding protein
AN935_01985	COG4607	ABC-type enterochelin transport system periplasmic component
AN935_01990	COG2814	Major facilitator Superfamily
AN935_01995	COG1309	transcriptional regulator
AN935_02000	COG0778	Nitroreductase
AN935_02005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN935_02010	COG0640	Transcriptional regulator
AN935_02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_02020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN935_02025	COG1012	belongs to the aldehyde dehydrogenase family
AN935_02030	COG4975	Glucose uptake
AN935_02035	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_02040	COG4549	nuclear export factor GLE1
AN935_02045	COG2372	response to copper ion
AN935_02045	COG1276	copper resistance
AN935_02050	COG1349	DNA-binding transcription factor activity
AN935_02060	COG2213	PTS system mannitol-specific
AN935_02065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_02070	COG0246	Mannitol dehydrogenase
AN935_02075	COG0473	3-isopropylmalate dehydrogenase activity
AN935_02080	COG0412	Dienelactone hydrolase
AN935_02085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN935_02095	COG0561	phosphatase activity
AN935_02100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AN935_02105	COG1914	H( )-stimulated, divalent metal cation uptake system
AN935_02110	COG4336	lyase activity
AN935_02115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AN935_02120	COG1984	allophanate hydrolase subunit 2
AN935_02125	COG1414	Transcriptional regulator
AN935_02130	COG2755	lipolytic protein G-D-S-L family
AN935_02140	COG2329	Antibiotic biosynthesis monooxygenase
AN935_02145	COG0768	penicillin binding
AN935_02150	COG4989	oxidoreductase activity
AN935_02155	COG3711	transcriptional antiterminator
AN935_02160	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_02165	COG2226	methyltransferase
AN935_02170	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_02175	COG1917	Cupin 2, conserved barrel domain protein
AN935_02180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_02185	COG3871	stress protein (general stress protein 26)
AN935_02195	COG2814	Major facilitator Superfamily
AN935_02200	COG1522	sequence-specific DNA binding
AN935_02205	COG0551	DNA topoisomerase type I activity
AN935_02205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN935_02210	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AN935_02215	COG3706	GGDEF domain
AN935_02220	COG5298	Protein conserved in bacteria
AN935_02225	COG1215	transferase activity, transferring glycosyl groups
AN935_02235	COG0531	amino acid
AN935_02245	COG0028	Belongs to the TPP enzyme family
AN935_02260	COG1914	H( )-stimulated, divalent metal cation uptake system
AN935_02265	COG2261	transglycosylase associated protein
AN935_02270	COG4876	unkown
AN935_02275	COG2217	Heavy metal translocating P-type atpase
AN935_02280	COG3729	General stress protein
AN935_02285	COG0662	Cupin 2, conserved barrel domain protein
AN935_02290	COG2329	Antibiotic biosynthesis monooxygenase
AN935_02295	COG3546	catalase activity
AN935_02300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AN935_02305	COG3290	protein histidine kinase activity
AN935_02310	COG4565	transcriptional regulatory protein
AN935_02315	COG1301	dicarboxylic acid transport
AN935_02320	COG0628	permease
AN935_02325	COG1301	dicarboxylic acid transport
AN935_02330	COG1131	(ABC) transporter
AN935_02335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AN935_02345	COG1960	acyl-CoA dehydrogenase activity
AN935_02360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN935_02365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_02370	COG1181	Belongs to the D-alanine--D-alanine ligase family
AN935_02375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AN935_02385	COG0513	Belongs to the DEAD box helicase family
AN935_02390	COG3402	PFAM membrane-flanked domain
AN935_02395	COG3428	Bacterial PH domain
AN935_02400	COG0705	Rhomboid family
AN935_02405	COG0736	holo-[acyl-carrier-protein] synthase activity
AN935_02410	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AN935_02415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN935_02420	COG0864	Transcriptional regulator
AN935_02425	COG2337	Toxic component of a toxin-antitoxin (TA) module
AN935_02430	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_02435	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_02440	COG2172	sigma factor antagonist activity
AN935_02445	COG2208	phosphoserine phosphatase activity
AN935_02450	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_02455	COG2172	sigma factor antagonist activity
AN935_02460	COG1191	sigma factor activity
AN935_02465	COG2208	phosphoserine phosphatase activity
AN935_02470	COG2183	response to ionizing radiation
AN935_02480	COG3091	SprT-like family
AN935_02525	COG1846	Transcriptional regulator
AN935_02530	COG2070	2-Nitropropane dioxygenase
AN935_02535	COG0431	NADPH-dependent FMN reductase
AN935_02540	COG0789	Transcriptional regulator
AN935_02540	COG4978	Transcriptional regulator
AN935_02545	COG0702	epimerase
AN935_02550	COG0697	spore germination
AN935_02555	COG0457	Tetratricopeptide repeat
AN935_02560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_02565	COG0697	spore germination
AN935_02570	COG1476	TRANSCRIPTIONal
AN935_02580	COG0791	NLP P60 protein
AN935_02580	COG0741	lytic transglycosylase activity
AN935_02590	COG2807	transmembrane transport
AN935_02600	COG1278	Cold shock
AN935_02605	COG1329	Transcriptional regulator
AN935_02610	COG2207	Transcriptional regulator
AN935_02610	COG3708	Transcriptional regulator
AN935_02620	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AN935_02625	COG2814	Major facilitator Superfamily
AN935_02635	COG1309	transcriptional regulator
AN935_02640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_02645	COG1316	TRANSCRIPTIONal
AN935_02660	COG5002	protein histidine kinase activity
AN935_02665	COG0745	RESPONSE REGULATOR receiver
AN935_02670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_02685	COG1114	Component of the transport system for branched-chain amino acids
AN935_02690	COG0583	DNA-binding transcription factor activity
AN935_02695	COG0114	fumarate hydratase activity
AN935_02700	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AN935_02705	COG1522	sequence-specific DNA binding
AN935_02710	COG0697	spore germination
AN935_02715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_02720	COG2030	dehydratase
AN935_02725	COG3545	Serine hydrolase
AN935_02730	COG1733	regulation of RNA biosynthetic process
AN935_02735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_02745	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN935_02750	COG0640	Transcriptional regulator
AN935_02755	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AN935_02760	COG0789	Transcriptional regulator
AN935_02765	COG0697	spore germination
AN935_02770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_02775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN935_02780	COG0640	Transcriptional regulator
AN935_02785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN935_02795	COG4585	Histidine kinase
AN935_02800	COG2197	response regulator
AN935_02805	COG2409	Drug exporters of the RND superfamily
AN935_02810	COG1811	Na channel or pump
AN935_02815	COG4978	Transcriptional regulator
AN935_02815	COG0789	Transcriptional regulator
AN935_02820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN935_02825	COG0778	Nitroreductase
AN935_02830	COG0346	lactoylglutathione lyase activity
AN935_02835	COG2259	Doxx family
AN935_02840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_02855	COG1309	transcriptional regulator
AN935_02865	COG0456	acetyltransferase
AN935_02870	COG0673	inositol 2-dehydrogenase activity
AN935_02875	COG1609	Transcriptional regulator
AN935_02880	COG2814	Major facilitator Superfamily
AN935_02885	COG1082	Xylose isomerase domain protein TIM barrel
AN935_02890	COG0488	(ABC) transporter
AN935_02895	COG1113	amino acid transport
AN935_02900	COG2318	DinB family
AN935_02905	COG1846	Transcriptional regulator
AN935_02910	COG1033	growth of symbiont in host cell
AN935_02910	COG2409	Drug exporters of the RND superfamily
AN935_02920	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_02925	COG0778	Nitroreductase
AN935_02930	COG1846	Transcriptional regulator
AN935_02935	COG1396	sequence-specific DNA binding
AN935_02950	COG2814	Major facilitator Superfamily
AN935_02955	COG0730	response to heat
AN935_02960	COG1802	Transcriptional regulator
AN935_02965	COG1388	LysM domain
AN935_02965	COG3858	chitin binding
AN935_02970	COG1819	glycosyl
AN935_02980	COG1785	Belongs to the alkaline phosphatase family
AN935_02985	COG5646	InterPro IPR014922
AN935_02995	COG0454	-acetyltransferase
AN935_03000	COG1078	dGTPase activity
AN935_03005	COG1388	LysM domain
AN935_03010	COG2814	Major facilitator Superfamily
AN935_03015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN935_03020	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN935_03030	COG2723	6-phospho-beta-galactosidase activity
AN935_03035	COG2188	Transcriptional regulator
AN935_03040	COG1940	carbohydrate kinase activity
AN935_03045	COG1482	cell wall glycoprotein biosynthetic process
AN935_03050	COG4124	Belongs to the glycosyl hydrolase 26 family
AN935_03080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AN935_03085	COG0802	atpase or kinase
AN935_03090	COG1214	PFAM Peptidase M22, glycoprotease
AN935_03095	COG0456	acetyltransferase
AN935_03100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AN935_03105	COG0488	(ABC) transporter
AN935_03110	COG0315	cyclic pyranopterin monophosphate synthase activity
AN935_03115	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AN935_03120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN935_03125	COG0805	protein transport
AN935_03135	COG1266	CAAX protease self-immunity
AN935_03145	COG0459	protein refolding
AN935_03150	COG1073	alpha beta
AN935_03155	COG0457	Tetratricopeptide repeat
AN935_03160	COG1063	alcohol dehydrogenase
AN935_03165	COG2211	Major facilitator Superfamily
AN935_03170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_03180	COG2814	Major facilitator Superfamily
AN935_03185	COG1063	alcohol dehydrogenase
AN935_03190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AN935_03195	COG0823	Involved in the tonB-independent uptake of proteins
AN935_03210	COG2267	carboxylic ester hydrolase activity
AN935_03220	COG2132	Multicopper oxidase
AN935_03225	COG1113	amino acid transport
AN935_03235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN935_03240	COG0714	Associated with various cellular activities
AN935_03245	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AN935_03250	COG1305	Transglutaminase-like
AN935_03255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AN935_03255	COG0519	Catalyzes the synthesis of GMP from XMP
AN935_03270	COG2252	PERMEase
AN935_03275	COG3064	Membrane
AN935_03285	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AN935_03295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AN935_03300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AN935_03305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AN935_03310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AN935_03315	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AN935_03320	COG0047	phosphoribosylformylglycinamidine synthase activity
AN935_03325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AN935_03330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AN935_03335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AN935_03340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AN935_03345	COG0138	bifunctional purine biosynthesis protein purh
AN935_03350	COG0151	Belongs to the GarS family
AN935_03355	COG1522	sequence-specific DNA binding
AN935_03360	COG0531	amino acid
AN935_03370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AN935_03375	COG1470	cell adhesion involved in biofilm formation
AN935_03380	COG4496	protein, YerC YecD
AN935_03385	COG0069	glutamate synthase activity
AN935_03390	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AN935_03395	COG0210	DNA helicase
AN935_03400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AN935_03405	COG4851	CamS sex pheromone cAM373 precursor
AN935_03410	COG2814	Major facilitator Superfamily
AN935_03430	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AN935_03435	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN935_03450	COG1960	acyl-CoA dehydrogenase activity
AN935_03480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN935_03485	COG1785	Belongs to the alkaline phosphatase family
AN935_03495	COG1285	pathogenesis
AN935_03500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_03505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN935_03510	COG0154	amidase activity
AN935_03515	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN935_03520	COG1309	transcriptional regulator
AN935_03525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN935_03530	COG1597	lipid kinase activity
AN935_03535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN935_03585	COG3391	amine dehydrogenase activity
AN935_03595	COG0457	Tetratricopeptide repeat
AN935_03605	COG0217	transcriptional regulatory protein
AN935_03615	COG1309	transcriptional regulator
AN935_03620	COG3631	Ketosteroid isomerase-related protein
AN935_03625	COG0702	epimerase
AN935_03640	COG3546	catalase activity
AN935_03645	COG0454	-acetyltransferase
AN935_03655	COG5578	integral membrane protein
AN935_03660	COG2972	Histidine kinase
AN935_03665	COG4753	response regulator
AN935_03665	COG2207	Transcriptional regulator
AN935_03670	COG1653	transport
AN935_03675	COG1175	transmembrane transport
AN935_03680	COG0395	ABC-type sugar transport system, permease component
AN935_03685	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AN935_03690	COG2207	Transcriptional regulator
AN935_03695	COG2755	lipolytic protein G-D-S-L family
AN935_03705	COG5578	integral membrane protein
AN935_03710	COG3401	FG-GAP repeat protein
AN935_03715	COG3401	FG-GAP repeat protein
AN935_03720	COG2755	lipolytic protein G-D-S-L family
AN935_03725	COG1874	Beta-galactosidase
AN935_03735	COG1653	transport
AN935_03740	COG4209	transmembrane transport
AN935_03745	COG0395	ABC-type sugar transport system, permease component
AN935_03750	COG1486	melibiose metabolic process
AN935_03755	COG2323	membrane
AN935_03760	COG2329	Antibiotic biosynthesis monooxygenase
AN935_03765	COG0346	lactoylglutathione lyase activity
AN935_03775	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_03780	COG5583	Uncharacterized small protein (DUF2292)
AN935_03785	COG0670	Belongs to the BI1 family
AN935_03790	COG0697	spore germination
AN935_03795	COG1846	Transcriptional regulator
AN935_03800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN935_03815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN935_03815	COG2124	cytochrome p450
AN935_03820	COG1368	sulfuric ester hydrolase activity
AN935_03825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AN935_03830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN935_03835	COG1442	glycosyl transferase family 8
AN935_03840	COG1216	Glycosyl transferase, family 2
AN935_03845	COG1442	glycosyl transferase family 8
AN935_03850	COG2223	nitrite transmembrane transporter activity
AN935_03855	COG1011	Hydrolase
AN935_03860	COG0531	amino acid
AN935_03865	COG1012	belongs to the aldehyde dehydrogenase family
AN935_03870	COG0840	transmembrane signaling receptor activity
AN935_03875	COG0488	(ABC) transporter
AN935_03885	COG0789	Transcriptional regulator
AN935_03890	COG2814	Major facilitator Superfamily
AN935_03895	COG0488	(ABC) transporter
AN935_03900	COG0513	Belongs to the DEAD box helicase family
AN935_03905	COG0456	acetyltransferase
AN935_03910	COG2130	NADP-dependent
AN935_03915	COG1120	ATPase activity
AN935_03920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_03925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_03930	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AN935_03945	COG3866	Pectate lyase
AN935_03950	COG0471	metal ion transport
AN935_03955	COG3290	protein histidine kinase activity
AN935_03960	COG4565	transcriptional regulatory protein
AN935_03965	COG3181	Tripartite tricarboxylate transporter family receptor
AN935_03975	COG2851	Citrate transporter
AN935_03980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_03985	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AN935_03990	COG1254	Belongs to the acylphosphatase family
AN935_03995	COG2258	MOSC domain
AN935_04015	COG0024	Methionine aminopeptidase
AN935_04020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_04020	COG1263	PTS System
AN935_04025	COG1368	sulfuric ester hydrolase activity
AN935_04035	COG1115	amino acid carrier protein
AN935_04045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_04045	COG1263	PTS System
AN935_04050	COG0366	Alpha amylase catalytic
AN935_04055	COG2188	Transcriptional regulator
AN935_04060	COG0778	Nitroreductase
AN935_04065	COG0737	Belongs to the 5'-nucleotidase family
AN935_04070	COG0693	protein deglycase activity
AN935_04075	COG2814	Major facilitator Superfamily
AN935_04080	COG4840	Belongs to the UPF0435 family
AN935_04085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN935_04090	COG4980	gas vesicle protein
AN935_04095	COG1295	ribonuclease BN
AN935_04105	COG0477	Major facilitator Superfamily
AN935_04115	COG0387	Pfam Sodium calcium exchanger
AN935_04125	COG0668	transmembrane transport
AN935_04130	COG0535	radical SAM domain protein
AN935_04140	COG0726	polysaccharide deacetylase
AN935_04145	COG2084	Dehydrogenase
AN935_04150	COG0598	Magnesium transport protein CorA
AN935_04155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AN935_04160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN935_04165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN935_04175	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AN935_04185	COG4637	Psort location Cytoplasmic, score
AN935_04190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN935_04195	COG0022	dehydrogenase e1 component
AN935_04200	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN935_04205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN935_04210	COG3284	Transcriptional regulator
AN935_04220	COG1742	UPF0060 membrane protein
AN935_04240	COG4842	Belongs to the WXG100 family
AN935_04245	COG1486	melibiose metabolic process
AN935_04250	COG1737	Transcriptional regulator
AN935_04255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_04255	COG1263	PTS System
AN935_04260	COG1132	(ABC) transporter
AN935_04265	COG1132	(ABC) transporter
AN935_04270	COG2259	Doxx family
AN935_04275	COG2514	catechol 2,3-dioxygenase activity
AN935_04280	COG4977	sequence-specific DNA binding
AN935_04280	COG1917	Cupin 2, conserved barrel domain protein
AN935_04285	COG2814	Major facilitator Superfamily
AN935_04290	COG1082	Xylose isomerase domain protein TIM barrel
AN935_04295	COG0673	inositol 2-dehydrogenase activity
AN935_04300	COG4585	Histidine kinase
AN935_04305	COG2197	response regulator
AN935_04310	COG1131	(ABC) transporter
AN935_04315	COG0842	Transport permease protein
AN935_04315	COG1511	domain protein
AN935_04320	COG0842	Transport permease protein
AN935_04330	COG1695	Transcriptional regulator
AN935_04335	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AN935_04355	COG1131	(ABC) transporter
AN935_04360	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AN935_04365	COG2318	DinB family
AN935_04370	COG2814	Major facilitator Superfamily
AN935_04375	COG1846	Transcriptional regulator
AN935_04380	COG0392	lysyltransferase activity
AN935_04380	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AN935_04385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_04390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_04395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_04400	COG0384	phenazine biosynthesis protein PhzF
AN935_04405	COG0778	Nitroreductase
AN935_04420	COG1090	epimerase
AN935_04425	COG2137	regulation of response to DNA damage stimulus
AN935_04440	COG2814	Major facilitator Superfamily
AN935_04455	COG3103	Sh3 type 3 domain protein
AN935_04460	COG5658	integral membrane protein
AN935_04465	COG0596	Alpha beta hydrolase
AN935_04470	COG0463	Glycosyl transferase, family 2
AN935_04475	COG4485	Bacterial membrane protein, YfhO
AN935_04480	COG1988	membrane-bound metal-dependent
AN935_04485	COG1194	a g-specific adenine glycosylase
AN935_04495	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_04510	COG3557	Belongs to the UPF0374 family
AN935_04515	COG1132	(ABC) transporter
AN935_04520	COG4129	membrane
AN935_04525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AN935_04530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AN935_04535	COG0735	belongs to the Fur family
AN935_04575	COG4326	sporulation control protein
AN935_04585	COG5577	PFAM Coat F domain
AN935_04590	COG3340	Belongs to the peptidase S51 family
AN935_04595	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AN935_04605	COG0753	catalase activity
AN935_04610	COG1116	anion transmembrane transporter activity
AN935_04615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN935_04620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN935_04625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_04635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AN935_04645	COG1476	TRANSCRIPTIONal
AN935_04655	COG3382	B3 4 domain protein
AN935_04660	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AN935_04670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AN935_04675	COG0789	Transcriptional regulator
AN935_04680	COG1664	Polymer-forming cytoskeletal
AN935_04685	COG1664	Polymer-forming cytoskeletal
AN935_04690	COG2766	serine protein kinase
AN935_04695	COG2718	Belongs to the UPF0229 family
AN935_04705	COG1846	Transcriptional regulator
AN935_04710	COG1566	PFAM secretion protein HlyD family protein
AN935_04715	COG2814	Major facilitator Superfamily
AN935_04720	COG0655	NAD(P)H dehydrogenase (quinone) activity
AN935_04735	COG1725	Transcriptional regulator
AN935_04740	COG1131	(ABC) transporter
AN935_04745	COG1131	(ABC) transporter
AN935_04750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AN935_04755	COG1278	Cold shock
AN935_04760	COG1464	Belongs to the NlpA lipoprotein family
AN935_04765	COG3706	GGDEF domain
AN935_04770	COG1823	symporter activity
AN935_04775	COG0456	acetyltransferase
AN935_04780	COG1396	sequence-specific DNA binding
AN935_04800	COG5577	PFAM Coat F domain
AN935_04805	COG4085	toxin activity
AN935_04805	COG1525	nuclease
AN935_04805	COG0737	Belongs to the 5'-nucleotidase family
AN935_04810	COG3764	Sortase (surface protein transpeptidase)
AN935_04815	COG0564	pseudouridine synthase activity
AN935_04825	COG0517	IMP dehydrogenase activity
AN935_04830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN935_04835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN935_04835	COG3153	acetyltransferase
AN935_04845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AN935_04850	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AN935_04855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AN935_04860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN935_04865	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AN935_04870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN935_04875	COG4585	Histidine kinase
AN935_04875	COG2203	Gaf domain
AN935_04880	COG2197	response regulator
AN935_04885	COG0431	NADPH-dependent FMN reductase
AN935_04900	COG1388	LysM domain
AN935_04900	COG0791	NLP P60 protein
AN935_04905	COG1959	2 iron, 2 sulfur cluster binding
AN935_04910	COG0668	transmembrane transport
AN935_04915	COG2719	SpoVR family
AN935_04920	COG1785	Belongs to the alkaline phosphatase family
AN935_04925	COG1388	LysM domain
AN935_04925	COG0791	NLP P60 protein
AN935_04930	COG0583	DNA-binding transcription factor activity
AN935_04935	COG0372	Belongs to the citrate synthase family
AN935_04940	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_04945	COG0531	amino acid
AN935_04950	COG0733	neurotransmitter:sodium symporter activity
AN935_04955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_04960	COG0456	acetyltransferase
AN935_04975	COG1595	DNA-templated transcription, initiation
AN935_04980	COG0667	Aldo Keto reductase
AN935_04985	COG0204	Acyl-transferase
AN935_04990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN935_05000	COG1253	flavin adenine dinucleotide binding
AN935_05005	COG0789	Transcriptional regulator
AN935_05010	COG0436	Aminotransferase
AN935_05015	COG1253	flavin adenine dinucleotide binding
AN935_05020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AN935_05025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AN935_05030	COG0584	glycerophosphoryl diester phosphodiesterase
AN935_05040	COG0668	transmembrane transport
AN935_05045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AN935_05050	COG0726	polysaccharide deacetylase
AN935_05055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN935_05060	COG1757	Na H antiporter
AN935_05065	COG0589	response to stress
AN935_05075	COG1132	(ABC) transporter
AN935_05080	COG1132	(ABC) transporter
AN935_05085	COG0702	epimerase
AN935_05100	COG0189	ligase activity
AN935_05105	COG0189	ligase activity
AN935_05110	COG4399	Belongs to the UPF0754 family
AN935_05115	COG3679	Belongs to the UPF0342 family
AN935_05120	COG4335	DNA alkylation repair
AN935_05125	COG0561	phosphatase activity
AN935_05130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN935_05135	COG0475	glutathione-regulated potassium exporter activity
AN935_05140	COG0490	domain, Protein
AN935_05150	COG1024	Enoyl-CoA hydratase
AN935_05160	COG4152	abc transporter atp-binding protein
AN935_05165	COG1668	transmembrane transport
AN935_05170	COG0420	3'-5' exonuclease activity
AN935_05175	COG4717	serine-type aminopeptidase activity
AN935_05180	COG3481	metal-dependent phosphohydrolase, HD sub domain
AN935_05190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN935_05210	COG1846	Transcriptional regulator
AN935_05215	COG4980	gas vesicle protein
AN935_05230	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AN935_05235	COG0537	adenosine 5'-monophosphoramidase activity
AN935_05240	COG1131	(ABC) transporter
AN935_05245	COG4473	ABC transporter
AN935_05255	COG1473	amidohydrolase
AN935_05260	COG3069	C4-dicarboxylate transmembrane transporter activity
AN935_05270	COG2329	Antibiotic biosynthesis monooxygenase
AN935_05275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN935_05280	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AN935_05285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AN935_05290	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AN935_05295	COG1309	transcriptional regulator
AN935_05300	COG1511	domain protein
AN935_05305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN935_05310	COG4377	Putative membrane peptidase family (DUF2324)
AN935_05320	COG1363	Peptidase, m42
AN935_05325	COG4405	Protein conserved in bacteria
AN935_05330	COG1301	dicarboxylic acid transport
AN935_05340	COG1234	tRNA 3'-trailer cleavage
AN935_05345	COG0095	Lipoate-protein ligase
AN935_05350	COG0702	epimerase
AN935_05355	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_05365	COG0501	Belongs to the peptidase M48B family
AN935_05370	COG1404	Belongs to the peptidase S8 family
AN935_05375	COG0456	acetyltransferase
AN935_05380	COG0604	alcohol dehydrogenase
AN935_05390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AN935_05395	COG0406	alpha-ribazole phosphatase activity
AN935_05400	COG0183	Belongs to the thiolase family
AN935_05405	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_05410	COG1268	BioY protein
AN935_05415	COG0840	transmembrane signaling receptor activity
AN935_05420	COG0723	plastoquinol--plastocyanin reductase activity
AN935_05420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN935_05425	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_05435	COG4903	ComK protein
AN935_05440	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_05450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_05465	COG0398	Pfam SNARE associated Golgi protein
AN935_05470	COG0681	Belongs to the peptidase S26 family
AN935_05475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN935_05480	COG1846	Transcriptional regulator
AN935_05485	COG3180	Ammonia monooxygenase
AN935_05490	COG0477	Major facilitator Superfamily
AN935_05490	COG2814	Major facilitator Superfamily
AN935_05495	COG4533	DNA binding
AN935_05505	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AN935_05510	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AN935_05515	COG1074	ATP-dependent DNA helicase activity
AN935_05520	COG0420	3'-5' exonuclease activity
AN935_05525	COG0419	ATPase involved in DNA repair
AN935_05530	COG1403	HNH endonuclease
AN935_05575	COG5337	Spore coat protein CotH
AN935_05580	COG0179	Fumarylacetoacetate (FAA) hydrolase
AN935_05590	COG1404	Belongs to the peptidase S8 family
AN935_05600	COG0367	asparagine synthase
AN935_05605	COG1562	ergosterol biosynthetic process
AN935_05610	COG0534	Mate efflux family protein
AN935_05615	COG2207	Transcriptional regulator
AN935_05615	COG1917	Cupin 2, conserved barrel domain protein
AN935_05620	COG1609	Transcriptional regulator
AN935_05625	COG0673	inositol 2-dehydrogenase activity
AN935_05630	COG2318	DinB family
AN935_05635	COG1279	arginine transmembrane transporter activity
AN935_05640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_05645	COG1357	PFAM Pentapeptide repeats (8 copies)
AN935_05650	COG2267	carboxylic ester hydrolase activity
AN935_05655	COG0529	Catalyzes the synthesis of activated sulfate
AN935_05660	COG2046	Belongs to the sulfate adenylyltransferase family
AN935_05665	COG0175	sulfate reduction
AN935_05670	COG2045	Belongs to the ComB family
AN935_05675	COG1809	phosphosulfolactate synthase activity
AN935_05680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_05685	COG4948	Mandelate Racemase Muconate Lactonizing
AN935_05690	COG2814	Major facilitator Superfamily
AN935_05695	COG0454	-acetyltransferase
AN935_05700	COG2153	protein acetylation
AN935_05705	COG0646	methionine synthase
AN935_05705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AN935_05710	COG1666	GTP binding
AN935_05715	COG2996	Protein conserved in bacteria
AN935_05735	COG1695	Transcriptional regulator
AN935_05750	COG3227	Zinc metalloprotease (Elastase)
AN935_05755	COG1307	EDD domain protein, DegV family
AN935_05760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_05780	COG0561	phosphatase activity
AN935_05785	COG1073	alpha beta
AN935_05790	COG2151	metal-sulfur cluster biosynthetic enzyme
AN935_05800	COG0277	FAD linked oxidase domain protein
AN935_05805	COG2271	Major facilitator Superfamily
AN935_05810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AN935_05815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AN935_05825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN935_05830	COG0505	Belongs to the CarA family
AN935_05835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AN935_05840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AN935_05855	COG2267	carboxylic ester hydrolase activity
AN935_05865	COG1744	ABC transporter substrate-binding protein PnrA-like
AN935_05880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN935_05885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN935_05890	COG5504	Zn-dependent protease
AN935_05895	COG0444	Belongs to the ABC transporter superfamily
AN935_05900	COG4608	Belongs to the ABC transporter superfamily
AN935_05910	COG0601	transmembrane transport
AN935_05915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN935_05925	COG0180	Tryptophanyl-tRNA synthetase
AN935_05930	COG4166	transmembrane transport
AN935_05935	COG0601	transmembrane transport
AN935_05940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN935_05945	COG0444	Belongs to the ABC transporter superfamily
AN935_05950	COG4608	Belongs to the ABC transporter superfamily
AN935_05955	COG2814	Major facilitator Superfamily
AN935_05960	COG0456	acetyltransferase
AN935_05965	COG1393	Belongs to the ArsC family
AN935_05970	COG0861	Integral membrane protein TerC family
AN935_05975	COG4862	establishment of competence for transformation
AN935_05980	COG4469	Competence protein
AN935_05985	COG1164	Oligoendopeptidase f
AN935_06000	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AN935_06005	COG2346	COG2346, Truncated hemoglobins
AN935_06010	COG0741	lytic transglycosylase activity
AN935_06015	COG4116	CYTH
AN935_06025	COG2357	RelA SpoT domain protein
AN935_06030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN935_06035	COG0564	pseudouridine synthase activity
AN935_06040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AN935_06045	COG0569	domain protein
AN935_06045	COG0475	glutathione-regulated potassium exporter activity
AN935_06050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AN935_06055	COG0352	thiamine-phosphate diphosphorylase activity
AN935_06060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN935_06065	COG2104	thiamine diphosphate biosynthetic process
AN935_06070	COG2022	thiamine diphosphate biosynthetic process
AN935_06075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AN935_06080	COG0351	phosphomethylpyrimidine kinase
AN935_06085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AN935_06145	COG0210	DNA helicase
AN935_06155	COG2153	protein acetylation
AN935_06160	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AN935_06165	COG2382	esterase
AN935_06170	COG0626	cystathionine gamma-synthase activity
AN935_06175	COG0626	cystathionine gamma-synthase activity
AN935_06180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_06185	COG5505	Protein of unknown function (DUF819)
AN935_06195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN935_06200	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_06210	COG3711	transcriptional antiterminator
AN935_06210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_06215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN935_06215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN935_06215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_06220	COG1482	cell wall glycoprotein biosynthetic process
AN935_06235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_06245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AN935_06260	COG0109	protoheme IX farnesyltransferase activity
AN935_06270	COG0726	polysaccharide deacetylase
AN935_06290	COG5504	Zn-dependent protease
AN935_06295	COG2205	protein histidine kinase activity
AN935_06305	COG3383	formate dehydrogenase (NAD+) activity
AN935_06310	COG2427	Protein of unknown function (DUF1641)
AN935_06320	COG1051	belongs to the nudix hydrolase family
AN935_06330	COG2124	cytochrome p450
AN935_06335	COG1819	glycosyl
AN935_06345	COG1587	Uroporphyrinogen-III synthase
AN935_06350	COG0390	transport system, permease component
AN935_06355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN935_06360	COG0697	spore germination
AN935_06365	COG4297	protein containing double-stranded beta helix domain
AN935_06375	COG1252	NADH dehydrogenase
AN935_06380	COG1904	glucuronate isomerase
AN935_06385	COG2211	Major facilitator Superfamily
AN935_06390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AN935_06395	COG1063	alcohol dehydrogenase
AN935_06400	COG1312	Catalyzes the dehydration of D-mannonate
AN935_06405	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_06410	COG2271	Major facilitator Superfamily
AN935_06415	COG1609	Transcriptional regulator
AN935_06420	COG0246	Mannitol dehydrogenase
AN935_06425	COG2721	sulfolactate sulfo-lyase activity
AN935_06430	COG0730	response to heat
AN935_06435	COG2318	DinB family
AN935_06440	COG0457	Tetratricopeptide repeat
AN935_06450	COG2350	Protein conserved in bacteria
AN935_06455	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN935_06455	COG3409	Peptidoglycan-binding domain 1 protein
AN935_06455	COG1388	LysM domain
AN935_06465	COG4195	phage-related replication protein
AN935_06470	COG3546	catalase activity
AN935_06475	COG2856	Zn peptidase
AN935_06480	COG1396	sequence-specific DNA binding
AN935_06490	COG1522	sequence-specific DNA binding
AN935_06495	COG1484	DNA-dependent DNA replication
AN935_06520	COG1595	DNA-templated transcription, initiation
AN935_06525	COG3728	DNA packaging
AN935_06525	COG5484	DNA packaging
AN935_06530	COG1783	phage Terminase large subunit
AN935_06535	COG5518	Phage portal protein
AN935_06540	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AN935_06545	COG4653	Phage capsid family
AN935_06595	COG3953	SLT domain
AN935_06595	COG5412	phage tail tape measure protein
AN935_06600	COG1652	LysM domain
AN935_06605	COG4193	domain, Protein
AN935_06615	COG3628	GPW Gp25 family protein
AN935_06620	COG3299	homolog of phage Mu protein gp47
AN935_06625	COG3778	Protein conserved in bacteria
AN935_06665	COG3409	Peptidoglycan-binding domain 1 protein
AN935_06665	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN935_06680	COG0306	phosphate transporter
AN935_06685	COG1392	Phosphate transport regulator
AN935_06690	COG0531	amino acid
AN935_06695	COG0346	lactoylglutathione lyase activity
AN935_06700	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AN935_06705	COG0463	Glycosyl transferase, family 2
AN935_06715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN935_06720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN935_06725	COG2362	D-Aminopeptidase
AN935_06730	COG0601	transmembrane transport
AN935_06735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN935_06740	COG0444	Belongs to the ABC transporter superfamily
AN935_06745	COG4166	transmembrane transport
AN935_06750	COG1619	proteins homologs of microcin C7 resistance protein MccF
AN935_06755	COG4948	Mandelate Racemase Muconate Lactonizing
AN935_06760	COG0791	NLP P60 protein
AN935_06765	COG4608	Belongs to the ABC transporter superfamily
AN935_06770	COG2706	6-phosphogluconolactonase activity
AN935_06775	COG1834	amidinotransferase
AN935_06780	COG1607	acyl-coa hydrolase
AN935_06785	COG1017	nitric oxide dioxygenase activity
AN935_06785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN935_06795	COG2323	membrane
AN935_06800	COG2318	DinB family
AN935_06805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_06810	COG2076	Multidrug Resistance protein
AN935_06815	COG2076	Multidrug Resistance protein
AN935_06820	COG0788	formyltetrahydrofolate deformylase activity
AN935_06825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AN935_06830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AN935_06835	COG1764	response to oxidative stress
AN935_06840	COG1846	Transcriptional regulator
AN935_06845	COG1764	response to oxidative stress
AN935_06850	COG0463	Glycosyl transferase, family 2
AN935_06850	COG0457	Tetratricopeptide repeat
AN935_06855	COG0590	tRNA wobble adenosine to inosine editing
AN935_06865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN935_06870	COG1404	Belongs to the peptidase S8 family
AN935_06875	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_06880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AN935_06885	COG1122	ATPase activity
AN935_06890	COG4721	ABC-type cobalt transport system, permease component
AN935_06900	COG0745	RESPONSE REGULATOR receiver
AN935_06905	COG5002	protein histidine kinase activity
AN935_06905	COG3850	Histidine kinase
AN935_06910	COG3212	peptidase
AN935_06915	COG3212	peptidase
AN935_06930	COG2239	Acts as a magnesium transporter
AN935_06935	COG0789	Transcriptional regulator
AN935_06950	COG1846	Transcriptional regulator
AN935_06955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AN935_06960	COG0726	polysaccharide deacetylase
AN935_06965	COG1408	metallophosphoesterase
AN935_06975	COG0463	Glycosyl transferase, family 2
AN935_06980	COG1793	dna ligase
AN935_06980	COG3285	dna ligase
AN935_06985	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AN935_06990	COG3300	MHYT domain
AN935_06990	COG5001	Diguanylate cyclase
AN935_06995	COG0586	Pfam SNARE associated Golgi protein
AN935_07000	COG0861	Integral membrane protein TerC family
AN935_07005	COG1191	sigma factor activity
AN935_07025	COG0501	Belongs to the peptidase M48B family
AN935_07030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN935_07045	COG3594	Acyltransferase
AN935_07050	COG5002	protein histidine kinase activity
AN935_07055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN935_07065	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AN935_07070	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AN935_07075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN935_07080	COG0436	Aminotransferase
AN935_07085	COG1850	ribulose-bisphosphate carboxylase activity
AN935_07090	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AN935_07095	COG0235	Class ii aldolase
AN935_07100	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AN935_07105	COG3339	Conserved Protein
AN935_07120	COG3852	Histidine kinase
AN935_07125	COG1846	Transcriptional regulator
AN935_07130	COG1360	Flagellar Motor Protein
AN935_07135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AN935_07140	COG0542	response to heat
AN935_07145	COG3949	Membrane
AN935_07150	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AN935_07155	COG0720	synthase
AN935_07160	COG0602	queuosine metabolic process
AN935_07165	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AN935_07170	COG4641	Protein conserved in bacteria
AN935_07170	COG1388	LysM domain
AN935_07175	COG1388	LysM domain
AN935_07180	COG3858	chitin binding
AN935_07195	COG4873	Protein conserved in bacteria
AN935_07210	COG3773	Cell wall hydrolase
AN935_07215	COG2244	polysaccharide biosynthetic process
AN935_07220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_07225	COG2217	Heavy metal translocating P-type atpase
AN935_07235	COG0006	proline dipeptidase activity
AN935_07245	COG1609	Transcriptional regulator
AN935_07250	COG3711	transcriptional antiterminator
AN935_07255	COG2190	(PTS) system
AN935_07255	COG1263	PTS System
AN935_07255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_07260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_07265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN935_07275	COG1533	DNA photolyase activity
AN935_07280	COG0456	acetyltransferase
AN935_07285	COG0840	transmembrane signaling receptor activity
AN935_07290	COG2084	Dehydrogenase
AN935_07300	COG2340	Cysteine-rich secretory protein family
AN935_07305	COG0768	penicillin binding
AN935_07310	COG4191	Histidine kinase
AN935_07315	COG0436	Aminotransferase
AN935_07325	COG0835	chemotaxis
AN935_07325	COG0784	Response regulator, receiver
AN935_07335	COG2814	Major facilitator Superfamily
AN935_07340	COG1376	ErfK ybiS ycfS ynhG family protein
AN935_07345	COG1408	metallophosphoesterase
AN935_07350	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_07355	COG2200	EAL domain
AN935_07365	COG4703	Protein of unknown function (DUF1797)
AN935_07370	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AN935_07380	COG0517	IMP dehydrogenase activity
AN935_07385	COG0583	DNA-binding transcription factor activity
AN935_07390	COG0716	FMN binding
AN935_07400	COG0716	FMN binding
AN935_07405	COG2171	N-acyltransferase activity
AN935_07410	COG1473	amidohydrolase
AN935_07420	COG0668	transmembrane transport
AN935_07425	COG0450	alkyl hydroperoxide reductase
AN935_07430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_07445	COG0746	molybdenum cofactor guanylyltransferase activity
AN935_07450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AN935_07455	COG0303	'Molybdopterin
AN935_07460	COG1763	Mo-molybdopterin cofactor biosynthetic process
AN935_07465	COG0314	molybdopterin synthase activity
AN935_07470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AN935_07475	COG1132	(ABC) transporter
AN935_07480	COG1132	(ABC) transporter
AN935_07490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN935_07495	COG1136	(ABC) transporter
AN935_07500	COG0577	efflux transmembrane transporter activity
AN935_07505	COG1349	DNA-binding transcription factor activity
AN935_07510	COG1105	Belongs to the carbohydrate kinase PfkB family
AN935_07515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_07515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN935_07515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN935_07520	COG0681	Belongs to the peptidase S26 family
AN935_07530	COG0488	(ABC) transporter
AN935_07535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AN935_07540	COG2309	aminopeptidase activity
AN935_07550	COG1077	Cell shape determining protein MreB Mrl
AN935_07555	COG2002	toxin-antitoxin pair type II binding
AN935_07560	COG3852	Histidine kinase
AN935_07565	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AN935_07565	COG2105	PFAM AIG2 family protein
AN935_07570	COG0569	domain protein
AN935_07575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AN935_07580	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AN935_07585	COG5503	Protein of unknown function (DUF1447)
AN935_07590	COG0561	phosphatase activity
AN935_07595	COG0242	peptide deformylase activity
AN935_07605	COG0497	DNA recombination
AN935_07610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN935_07615	COG0022	dehydrogenase e1 component
AN935_07620	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN935_07625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN935_07630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_07635	COG1982	Orn Lys Arg decarboxylase major
AN935_07640	COG4476	Belongs to the UPF0223 family
AN935_07645	COG4493	Belongs to the UPF0637 family
AN935_07655	COG0483	inositol monophosphate 1-phosphatase activity
AN935_07670	COG0657	acetylesterase activity
AN935_07675	COG1959	2 iron, 2 sulfur cluster binding
AN935_07695	COG1595	DNA-templated transcription, initiation
AN935_07715	COG1217	gtp-binding protein TYPA
AN935_07725	COG4896	Protein conserved in bacteria
AN935_07735	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AN935_07740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AN935_07745	COG2066	Belongs to the glutaminase family
AN935_07750	COG4838	Belongs to the UPF0358 family
AN935_07755	COG0772	Belongs to the SEDS family
AN935_07760	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AN935_07770	COG1612	heme a metabolic process
AN935_07775	COG0109	protoheme IX farnesyltransferase activity
AN935_07780	COG2010	Cytochrome c
AN935_07780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AN935_07785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AN935_07790	COG1845	cytochrome c oxidase, subunit III
AN935_07795	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AN935_07800	COG3336	cytochrome c oxidase
AN935_07810	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AN935_07815	COG2340	Cysteine-rich secretory protein family
AN935_07830	COG3679	Belongs to the UPF0342 family
AN935_07835	COG4471	UPF0298 protein
AN935_07840	COG0742	ribosomal rna small subunit methyltransferase
AN935_07845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AN935_07850	COG3314	Sporulation integral membrane protein YlbJ
AN935_07855	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN935_07860	COG3480	Lon protease (S16) C-terminal proteolytic domain
AN935_07865	COG1323	Belongs to the UPF0348 family
AN935_07875	COG1399	metal-binding, possibly nucleic acid-binding protein
AN935_07890	COG0454	-acetyltransferase
AN935_07895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AN935_07900	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AN935_07905	COG2001	Belongs to the MraZ family
AN935_07910	COG0275	rRNA processing
AN935_07915	COG4839	cell division protein FtsL
AN935_07920	COG0768	penicillin binding
AN935_07930	COG0768	penicillin binding
AN935_07935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AN935_07945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN935_07950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AN935_07955	COG0772	Belongs to the SEDS family
AN935_07960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AN935_07965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AN935_07970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AN935_07975	COG3879	Bacterial protein of unknown function (DUF881)
AN935_07980	COG3879	Bacterial protein of unknown function (DUF881)
AN935_07985	COG3856	small basic protein
AN935_07990	COG0849	cell division
AN935_07995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AN935_08000	COG1404	Belongs to the peptidase S8 family
AN935_08000	COG4412	M6 family metalloprotease domain protein
AN935_08010	COG1191	sigma factor activity
AN935_08015	COG1191	sigma factor activity
AN935_08020	COG1119	ATPase activity
AN935_08025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN935_08030	COG1873	PFAM PRC-barrel domain
AN935_08035	COG1496	oxidoreductase activity
AN935_08040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AN935_08045	COG1799	cell septum assembly
AN935_08050	COG0762	integral membrane protein
AN935_08055	COG2302	S4 RNA-binding domain
AN935_08060	COG3599	regulation of cell shape
AN935_08065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AN935_08070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN935_08075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AN935_08080	COG0564	pseudouridine synthase activity
AN935_08085	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AN935_08090	COG2233	PERMEase
AN935_08095	COG0540	Belongs to the ATCase OTCase family
AN935_08100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AN935_08105	COG0505	Belongs to the CarA family
AN935_08110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AN935_08115	COG0543	2 iron, 2 sulfur cluster binding
AN935_08120	COG0167	dihydroorotate dehydrogenase activity
AN935_08125	COG0284	orotidine-5'-phosphate decarboxylase activity
AN935_08130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AN935_08135	COG0175	sulfate reduction
AN935_08140	COG0306	phosphate transporter
AN935_08145	COG2046	Belongs to the sulfate adenylyltransferase family
AN935_08150	COG0529	Catalyzes the synthesis of activated sulfate
AN935_08155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN935_08160	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AN935_08165	COG1648	precorrin-2 dehydrogenase activity
AN935_08170	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AN935_08175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AN935_08180	COG1561	YicC-like family, N-terminal region
AN935_08190	COG0194	GDP metabolic process
AN935_08195	COG1758	RNA polymerase activity
AN935_08200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN935_08205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AN935_08210	COG0242	peptide deformylase activity
AN935_08215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AN935_08220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AN935_08220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN935_08225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AN935_08230	COG0631	protein serine/threonine phosphatase activity
AN935_08235	COG0515	serine threonine protein kinase
AN935_08235	COG2815	serine threonine protein kinase
AN935_08240	COG1162	GTPase activity
AN935_08245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AN935_08250	COG1564	THIamine pyrophosphokinase
AN935_08260	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AN935_08265	COG1302	Protein conserved in bacteria
AN935_08270	COG1461	Dihydroxyacetone kinase
AN935_08275	COG1760	l-serine dehydratase
AN935_08280	COG1760	l-serine dehydratase
AN935_08285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AN935_08290	COG2050	protein possibly involved in aromatic compounds catabolism
AN935_08290	COG1349	DNA-binding transcription factor activity
AN935_08295	COG0416	fatty acid biosynthetic process
AN935_08300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AN935_08305	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_08315	COG0571	ribonuclease III activity
AN935_08320	COG1196	nuclear chromosome segregation
AN935_08325	COG0552	protein localization to endoplasmic reticulum
AN935_08335	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AN935_08340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AN935_08345	COG0228	four-way junction DNA binding
AN935_08350	COG1837	Belongs to the UPF0109 family
AN935_08360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AN935_08365	COG0336	Belongs to the RNA methyltransferase TrmD family
AN935_08370	COG0335	large ribosomal subunit rRNA binding
AN935_08375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AN935_08380	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN935_08390	COG2257	FlhB HrpN YscU SpaS Family
AN935_08395	COG0045	succinate-CoA ligase (ADP-forming) activity
AN935_08400	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AN935_08405	COG0758	DNA mediated transformation
AN935_08410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN935_08415	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AN935_08420	COG4974	Belongs to the 'phage' integrase family
AN935_08425	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AN935_08430	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AN935_08435	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AN935_08440	COG1815	bacterial-type flagellum-dependent cell motility
AN935_08445	COG1558	bacterial-type flagellum-dependent cell motility
AN935_08450	COG1677	Flagellar hook-basal body complex protein FliE
AN935_08455	COG1766	The M ring may be actively involved in energy transduction
AN935_08460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AN935_08465	COG1317	bacterial-type flagellum organization
AN935_08470	COG1157	protein secretion by the type III secretion system
AN935_08475	COG2882	bacterial-type flagellum organization
AN935_08480	COG3334	PFAM MgtE intracellular
AN935_08485	COG3144	bacterial-type flagellum assembly
AN935_08490	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AN935_08495	COG4786	Flagellar basal body rod
AN935_08500	COG1582	Flagellar protein (FlbD)
AN935_08505	COG1580	Controls the rotational direction of flagella during chemotaxis
AN935_08510	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AN935_08515	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AN935_08515	COG1776	CheC inhibitor of MCP methylation
AN935_08520	COG2201	protein-glutamate methylesterase activity
AN935_08525	COG3190	flagellar
AN935_08530	COG1338	Plays a role in the flagellum-specific transport system
AN935_08535	COG1987	bacterial-type flagellum assembly
AN935_08540	COG1684	flagellar biosynthetic protein fliR
AN935_08545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AN935_08550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AN935_08555	COG1419	protein localization to endoplasmic reticulum
AN935_08560	COG0455	bacterial-type flagellum organization
AN935_08565	COG2201	protein-glutamate methylesterase activity
AN935_08570	COG0643	Histidine kinase
AN935_08570	COG2198	Histidine kinase
AN935_08575	COG0835	chemotaxis
AN935_08580	COG1776	CheC inhibitor of MCP methylation
AN935_08585	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AN935_08590	COG1191	sigma factor activity
AN935_08600	COG0052	Belongs to the universal ribosomal protein uS2 family
AN935_08605	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AN935_08610	COG0528	UMP kinase activity
AN935_08615	COG0233	cytoplasmic translational termination
AN935_08620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AN935_08625	COG4589	Belongs to the CDS family
AN935_08630	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AN935_08635	COG0750	zinc metalloprotease
AN935_08640	COG0442	prolyl-tRNA aminoacylation
AN935_08645	COG2176	DNA-directed DNA polymerase activity
AN935_08650	COG0779	Required for maturation of 30S ribosomal subunits
AN935_08655	COG0195	Participates in both transcription termination and antitermination
AN935_08660	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AN935_08665	COG1358	cellular component organization or biogenesis
AN935_08670	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AN935_08675	COG1550	Protein conserved in bacteria
AN935_08680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AN935_08685	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AN935_08690	COG0196	riboflavin kinase activity
AN935_08700	COG1185	polyribonucleotide nucleotidyltransferase activity
AN935_08705	COG0726	polysaccharide deacetylase
AN935_08710	COG0612	Peptidase, M16
AN935_08715	COG1873	PFAM PRC-barrel domain
AN935_08725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN935_08730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN935_08735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AN935_08740	COG0527	aspartate kinase activity
AN935_08745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN935_08750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AN935_08755	COG0740	serine-type endopeptidase activity
AN935_08765	COG4980	gas vesicle protein
AN935_08765	COG1674	ftsk spoiiie
AN935_08770	COG2188	Transcriptional regulator
AN935_08775	COG2814	Major facilitator Superfamily
AN935_08780	COG0612	Peptidase, M16
AN935_08785	COG0612	Peptidase, M16
AN935_08790	COG0300	oxidoreductase activity
AN935_08805	COG1426	Protein conserved in bacteria
AN935_08810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AN935_08815	COG1546	Belongs to the CinA family
AN935_08815	COG1058	Belongs to the CinA family
AN935_08820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AN935_08825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN935_08830	COG1418	mRNA catabolic process
AN935_08835	COG1692	metallophosphoesterase
AN935_08840	COG2359	stage V sporulation protein S
AN935_08845	COG1063	alcohol dehydrogenase
AN935_08850	COG0156	8-amino-7-oxononanoate synthase activity
AN935_08855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AN935_08860	COG4550	Control of competence regulator ComK, YlbF/YmcA
AN935_08870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AN935_08875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AN935_08910	COG3226	Transcriptional regulator
AN935_08920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_08925	COG1404	Belongs to the peptidase S8 family
AN935_08935	COG4195	phage-related replication protein
AN935_08940	COG1764	response to oxidative stress
AN935_08965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AN935_08970	COG1923	regulation of RNA biosynthetic process
AN935_08985	COG1780	Probably involved in ribonucleotide reductase function
AN935_08990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN935_08995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN935_09000	COG4112	unkown
AN935_09005	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_09010	COG0464	growth
AN935_09020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AN935_09025	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AN935_09030	COG0789	Transcriptional regulator
AN935_09035	COG0174	glutamine synthetase
AN935_09060	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN935_09065	COG1733	regulation of RNA biosynthetic process
AN935_09095	COG0135	phosphoribosylanthranilate isomerase activity
AN935_09120	COG2211	Major facilitator Superfamily
AN935_09125	COG3507	Belongs to the glycosyl hydrolase 43 family
AN935_09140	COG1070	Carbohydrate kinase
AN935_09150	COG1525	nuclease
AN935_09155	COG2814	Major facilitator Superfamily
AN935_09165	COG0756	dUTP diphosphatase activity
AN935_09210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN935_09220	COG3832	glyoxalase III activity
AN935_09235	COG2059	Chromate
AN935_09240	COG0697	spore germination
AN935_09245	COG0531	amino acid
AN935_09275	COG4195	phage-related replication protein
AN935_09285	COG0346	lactoylglutathione lyase activity
AN935_09295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AN935_09300	COG1388	LysM domain
AN935_09305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AN935_09310	COG4224	UPF0291 protein
AN935_09315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AN935_09325	COG3763	UPF0154 protein
AN935_09335	COG0785	Cytochrome C biogenesis protein
AN935_09340	COG2201	protein-glutamate methylesterase activity
AN935_09345	COG4846	Membrane protein involved in cytochrome C biogenesis
AN935_09355	COG0071	Belongs to the small heat shock protein (HSP20) family
AN935_09370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AN935_09375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_09395	COG0824	Thioesterase
AN935_09405	COG4841	protein insertion into membrane
AN935_09410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AN935_09415	COG1832	CoA-binding protein
AN935_09420	COG0187	DNA topoisomerase II activity
AN935_09425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AN935_09440	COG1115	amino acid carrier protein
AN935_09455	COG5520	Belongs to the glycosyl hydrolase 30 family
AN935_09480	COG2246	polysaccharide biosynthetic process
AN935_09485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN935_09490	COG0586	Pfam SNARE associated Golgi protein
AN935_09495	COG2404	hydrolase activity, acting on ester bonds
AN935_09500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AN935_09505	COG1024	Enoyl-CoA hydratase
AN935_09510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN935_09515	COG0511	ligase activity, forming carbon-carbon bonds
AN935_09520	COG0439	Biotin carboxylase
AN935_09525	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_09530	COG1960	acyl-CoA dehydrogenase activity
AN935_09550	COG1649	PFAM Uncharacterised BCR, COG1649
AN935_09560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_09560	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AN935_09570	COG2027	D-alanyl-D-alanine carboxypeptidase
AN935_09575	COG2017	converts alpha-aldose to the beta-anomer
AN935_09580	COG0534	Mate efflux family protein
AN935_09595	COG0582	viral genome integration into host DNA
AN935_09600	COG0166	Belongs to the GPI family
AN935_09605	COG0405	Gamma-glutamyltransferase
AN935_09610	COG0583	DNA-binding transcription factor activity
AN935_09615	COG0604	alcohol dehydrogenase
AN935_09620	COG0493	'glutamate synthase
AN935_09625	COG0070	glutamate synthase
AN935_09625	COG0067	glutamate synthase
AN935_09625	COG0069	glutamate synthase activity
AN935_09630	COG0583	DNA-binding transcription factor activity
AN935_09635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AN935_09650	COG0300	oxidoreductase activity
AN935_09655	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AN935_09665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_09670	COG2814	Major facilitator Superfamily
AN935_09675	COG1070	Carbohydrate kinase
AN935_09680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN935_09685	COG0243	molybdopterin cofactor binding
AN935_09700	COG1082	Xylose isomerase domain protein TIM barrel
AN935_09715	COG0840	transmembrane signaling receptor activity
AN935_09715	COG5278	phosphoserine phosphatase activity
AN935_09720	COG2368	4-hydroxyphenylacetate
AN935_09725	COG4305	rare lipoprotein A
AN935_09730	COG3619	membrane
AN935_09755	COG2135	peptidase activity
AN935_09765	COG2140	Oxalate decarboxylase
AN935_09775	COG0457	Tetratricopeptide repeat
AN935_09800	COG2720	vancomycin resistance protein
AN935_09810	COG3655	Transcriptional regulator
AN935_09815	COG3739	integral membrane protein
AN935_09820	COG0583	DNA-binding transcription factor activity
AN935_09825	COG0697	spore germination
AN935_09835	COG1388	LysM domain
AN935_09845	COG0693	protein deglycase activity
AN935_09850	COG2367	Beta-lactamase
AN935_09855	COG4282	regulation of fungal-type cell wall biogenesis
AN935_09860	COG3397	chitin binding
AN935_09865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_09870	COG0574	Belongs to the PEP-utilizing enzyme family
AN935_09870	COG3848	Pyruvate phosphate dikinase
AN935_09880	COG4282	regulation of fungal-type cell wall biogenesis
AN935_09885	COG1231	oxidoreductase activity
AN935_09890	COG0726	polysaccharide deacetylase
AN935_09895	COG1793	dna ligase
AN935_09955	COG3655	Transcriptional regulator
AN935_09995	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AN935_10000	COG0463	Glycosyl transferase, family 2
AN935_10005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_10010	COG3271	cysteine-type peptidase activity
AN935_10010	COG2274	protein secretion by the type I secretion system
AN935_10025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN935_10080	COG1404	Belongs to the peptidase S8 family
AN935_10090	COG1404	Belongs to the peptidase S8 family
AN935_10100	COG1136	(ABC) transporter
AN935_10100	COG0577	efflux transmembrane transporter activity
AN935_10115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_10120	COG2207	Transcriptional regulator
AN935_10120	COG0662	Cupin 2, conserved barrel domain protein
AN935_10125	COG0456	acetyltransferase
AN935_10130	COG1309	transcriptional regulator
AN935_10135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_10140	COG3708	Transcriptional regulator
AN935_10145	COG2378	regulation of single-species biofilm formation
AN935_10155	COG0640	Transcriptional regulator
AN935_10160	COG0741	lytic transglycosylase activity
AN935_10165	COG2322	membrane
AN935_10180	COG1619	proteins homologs of microcin C7 resistance protein MccF
AN935_10185	COG3239	Fatty acid desaturase
AN935_10190	COG4585	Histidine kinase
AN935_10195	COG2197	response regulator
AN935_10200	COG1388	LysM domain
AN935_10200	COG3584	3D domain protein
AN935_10205	COG0514	ATP-dependent DNA helicase (RecQ)
AN935_10215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AN935_10220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN935_10235	COG1012	belongs to the aldehyde dehydrogenase family
AN935_10240	COG1657	PFAM Prenyltransferase squalene oxidase
AN935_10245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AN935_10250	COG0733	neurotransmitter:sodium symporter activity
AN935_10255	COG0385	Bile acid
AN935_10260	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN935_10265	COG0567	Dehydrogenase, E1 component
AN935_10270	COG4548	von Willebrand factor, type A
AN935_10275	COG0714	Associated with various cellular activities
AN935_10280	COG2032	superoxide dismutase activity
AN935_10285	COG1388	LysM domain
AN935_10285	COG0791	NLP P60 protein
AN935_10290	COG1819	glycosyl
AN935_10295	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AN935_10300	COG0534	Mate efflux family protein
AN935_10305	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_10310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AN935_10315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AN935_10325	COG2962	Rard protein
AN935_10340	COG2610	gluconate transmembrane transporter activity
AN935_10345	COG1942	4-Oxalocrotonate Tautomerase
AN935_10355	COG1733	regulation of RNA biosynthetic process
AN935_10360	COG0778	Nitroreductase
AN935_10365	COG0400	carboxylic ester hydrolase activity
AN935_10370	COG0346	lactoylglutathione lyase activity
AN935_10380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_10385	COG0793	Belongs to the peptidase S41A family
AN935_10385	COG3409	Peptidoglycan-binding domain 1 protein
AN935_10390	COG2226	methyltransferase
AN935_10400	COG1876	peptidase activity
AN935_10405	COG0813	purine-nucleoside phosphorylase activity
AN935_10420	COG0671	phosphoesterase, PA-phosphatase related
AN935_10445	COG4479	Belongs to the UPF0346 family
AN935_10455	COG1509	lysine 2,3-aminomutase activity
AN935_10460	COG0456	acetyltransferase
AN935_10465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN935_10470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN935_10475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN935_10480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AN935_10495	COG0456	acetyltransferase
AN935_10500	COG0463	Glycosyl transferase, family 2
AN935_10515	COG4641	Protein conserved in bacteria
AN935_10520	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AN935_10525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN935_10535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN935_10540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN935_10545	COG1846	Transcriptional regulator
AN935_10550	COG0534	Mate efflux family protein
AN935_10560	COG4698	Protein conserved in bacteria
AN935_10565	COG2755	lipolytic protein G-D-S-L family
AN935_10570	COG1999	signal sequence binding
AN935_10580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN935_10585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AN935_10590	COG1272	protein, Hemolysin III
AN935_10595	COG0204	Acyl-transferase
AN935_10600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AN935_10610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AN935_10620	COG2136	Putative SAM-dependent methyltransferase
AN935_10620	COG2521	methyltransferase
AN935_10630	COG0129	dihydroxy-acid dehydratase activity
AN935_10635	COG1413	lyase activity
AN935_10640	COG1418	mRNA catabolic process
AN935_10645	COG0386	Belongs to the glutathione peroxidase family
AN935_10650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AN935_10655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AN935_10660	COG1278	Cold shock
AN935_10680	COG0328	RNA-DNA hybrid ribonuclease activity
AN935_10685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AN935_10690	COG0328	RNA-DNA hybrid ribonuclease activity
AN935_10700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN935_10715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AN935_10720	COG1755	Isoprenylcysteine carboxyl methyltransferase
AN935_10725	COG3424	synthase
AN935_10730	COG2233	PERMEase
AN935_10735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN935_10740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AN935_10750	COG0800	Aldolase
AN935_10755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_10760	COG1609	Transcriptional regulator
AN935_10765	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AN935_10770	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_10775	COG1199	ATP-dependent helicase activity
AN935_10785	COG0116	Belongs to the methyltransferase superfamily
AN935_10800	COG4474	Belongs to the UPF0398 family
AN935_10810	COG3359	exonuclease
AN935_10815	COG1111	helicase
AN935_10815	COG1205	dead DEAH box helicase
AN935_10820	COG2190	(PTS) system
AN935_10825	COG0071	Belongs to the small heat shock protein (HSP20) family
AN935_10860	COG3331	DNA recombination
AN935_10865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN935_10865	COG4499	WXG100 protein secretion system (Wss), protein YukC
AN935_10875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AN935_10880	COG3935	DnaD domain protein
AN935_10885	COG0017	Asparaginyl-tRNA synthetase
AN935_10890	COG0436	Aminotransferase
AN935_10895	COG5353	protein conserved in bacteria
AN935_10905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN935_10905	COG1199	ATP-dependent helicase activity
AN935_10910	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AN935_10915	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AN935_10920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AN935_10925	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AN935_10925	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AN935_10930	COG0617	tRNA 3'-terminal CCA addition
AN935_10935	COG0438	transferase activity, transferring glycosyl groups
AN935_10940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AN935_10945	COG1803	Methylglyoxal synthase
AN935_10950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AN935_10955	COG1694	Mazg nucleotide pyrophosphohydrolase
AN935_10960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_10970	COG4347	Protein of unknown function (DUF1405)
AN935_10975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AN935_10975	COG2010	Cytochrome c
AN935_10980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AN935_10985	COG0723	plastoquinol--plastocyanin reductase activity
AN935_10995	COG5582	Belongs to the UPF0302 family
AN935_11000	COG0457	Tetratricopeptide repeat
AN935_11005	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AN935_11010	COG0287	Prephenate dehydrogenase
AN935_11015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AN935_11020	COG0159	tryptophan synthase activity
AN935_11025	COG0133	tryptophan synthase activity
AN935_11030	COG0135	phosphoribosylanthranilate isomerase activity
AN935_11040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AN935_11045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN935_11050	COG4401	Chorismate mutase type I
AN935_11055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AN935_11060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AN935_11065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AN935_11070	COG0105	UTP biosynthetic process
AN935_11075	COG0142	geranyltranstransferase activity
AN935_11080	COG2226	methyltransferase
AN935_11085	COG0142	geranyltranstransferase activity
AN935_11095	COG0302	gtp cyclohydrolase
AN935_11100	COG0776	regulation of translation
AN935_11105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AN935_11120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AN935_11125	COG1160	GTP binding
AN935_11150	COG1304	FMN binding
AN935_11155	COG0539	negative regulation of cytoplasmic translation
AN935_11160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AN935_11170	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AN935_11175	COG2959	enzyme of heme biosynthesis
AN935_11180	COG3409	Peptidoglycan-binding domain 1 protein
AN935_11180	COG3773	Cell wall hydrolase
AN935_11185	COG2339	peptidase activity
AN935_11190	COG0492	ferredoxin-NADP+ reductase activity
AN935_11195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN935_11200	COG4862	establishment of competence for transformation
AN935_11205	COG1408	metallophosphoesterase
AN935_11215	COG1388	LysM domain
AN935_11220	COG1266	CAAX protease self-immunity
AN935_11225	COG0514	ATP-dependent DNA helicase (RecQ)
AN935_11230	COG4955	Helix-turn-helix domain
AN935_11235	COG1141	Ferredoxin
AN935_11240	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AN935_11245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN935_11250	COG0710	3-dehydroquinate dehydratase activity
AN935_11260	COG1595	DNA-templated transcription, initiation
AN935_11265	COG5002	protein histidine kinase activity
AN935_11270	COG0745	RESPONSE REGULATOR receiver
AN935_11275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN935_11280	COG1333	cytochrome c biogenesis protein
AN935_11285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_11290	COG1187	pseudouridine synthase activity
AN935_11295	COG0700	Nucleoside recognition
AN935_11300	COG2715	membrane protein required for spore maturation
AN935_11305	COG1686	Belongs to the peptidase S11 family
AN935_11315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AN935_11320	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AN935_11325	COG1547	Domain of unknown function (DUF309)
AN935_11330	COG0456	acetyltransferase
AN935_11335	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AN935_11340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AN935_11340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AN935_11345	COG0307	riboflavin synthase, alpha
AN935_11350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN935_11350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN935_11385	COG0534	Mate efflux family protein
AN935_11390	COG2226	methyltransferase
AN935_11400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AN935_11400	COG2070	2-Nitropropane dioxygenase
AN935_11405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN935_11410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_11420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_11420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN935_11420	COG3321	synthase
AN935_11420	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_11420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN935_11425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN935_11430	COG3425	synthase
AN935_11435	COG1024	Enoyl-CoA hydratase
AN935_11440	COG1024	Enoyl-CoA hydratase
AN935_11450	COG1082	Xylose isomerase domain protein TIM barrel
AN935_11455	COG1819	glycosyl
AN935_11470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_11485	COG0681	Belongs to the peptidase S26 family
AN935_11490	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AN935_11500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN935_11510	COG4086	secreted protein
AN935_11515	COG0019	diaminopimelate decarboxylase activity
AN935_11520	COG0697	spore germination
AN935_11535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN935_11555	COG1191	sigma factor activity
AN935_11565	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_11570	COG1686	Belongs to the peptidase S11 family
AN935_11575	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AN935_11580	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AN935_11585	COG4974	Belongs to the 'phage' integrase family
AN935_11595	COG0735	belongs to the Fur family
AN935_11600	COG1300	Membrane
AN935_11610	COG0281	malic enzyme
AN935_11615	COG1757	Na H antiporter
AN935_11620	COG1027	Aspartate ammonia-lyase
AN935_11625	COG0252	asparaginase activity
AN935_11630	COG1396	sequence-specific DNA binding
AN935_11635	COG1379	DNA repair
AN935_11640	COG0494	nUDIX hydrolase
AN935_11650	COG0667	Aldo Keto reductase
AN935_11660	COG1073	alpha beta
AN935_11670	COG4918	Iron-sulphur cluster biosynthesis
AN935_11675	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AN935_11675	COG0456	acetyltransferase
AN935_11680	COG2329	Antibiotic biosynthesis monooxygenase
AN935_11685	COG0456	acetyltransferase
AN935_11695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN935_11720	COG1072	(Pantothenic acid kinase))
AN935_11725	COG3048	D-serine ammonia-lyase activity
AN935_11730	COG0300	oxidoreductase activity
AN935_11735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_11740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN935_11745	COG4187	Peptidase family M20/M25/M40
AN935_11750	COG1902	pentaerythritol trinitrate reductase activity
AN935_11755	COG0596	Alpha beta hydrolase
AN935_11765	COG1234	tRNA 3'-trailer cleavage
AN935_11770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AN935_11775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AN935_11780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN935_11790	COG0706	membrane insertase activity
AN935_11795	COG3361	conserved protein (COG2071)
AN935_11800	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN935_11805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AN935_11810	COG0346	lactoylglutathione lyase activity
AN935_11820	COG1376	ErfK ybiS ycfS ynhG family protein
AN935_11825	COG4129	membrane
AN935_11830	COG1126	abc transporter atp-binding protein
AN935_11835	COG0765	amino acid transport
AN935_11840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_11850	COG1597	lipid kinase activity
AN935_11855	COG2814	Major facilitator Superfamily
AN935_11860	COG4978	Transcriptional regulator
AN935_11860	COG0789	Transcriptional regulator
AN935_11865	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN935_11870	COG0022	dehydrogenase e1 component
AN935_11875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN935_11880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN935_11885	COG3426	butyrate kinase activity
AN935_11890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN935_11895	COG0280	phosphate acetyltransferase
AN935_11900	COG3829	transcription factor binding
AN935_11900	COG3290	protein histidine kinase activity
AN935_11910	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AN935_11915	COG2079	MmgE PrpD family protein
AN935_11920	COG0372	Belongs to the citrate synthase family
AN935_11925	COG1960	acyl-CoA dehydrogenase activity
AN935_11930	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN935_11935	COG0183	Belongs to the thiolase family
AN935_11940	COG0584	glycerophosphoryl diester phosphodiesterase
AN935_11945	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_11960	COG1902	pentaerythritol trinitrate reductase activity
AN935_11970	COG0745	RESPONSE REGULATOR receiver
AN935_11980	COG0750	zinc metalloprotease
AN935_11985	COG0497	DNA recombination
AN935_11990	COG1438	arginine binding
AN935_11995	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AN935_12000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AN935_12005	COG0142	geranyltranstransferase activity
AN935_12010	COG1722	exodeoxyribonuclease VII activity
AN935_12015	COG1570	exodeoxyribonuclease VII activity
AN935_12020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AN935_12025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN935_12030	COG1302	Protein conserved in bacteria
AN935_12035	COG0439	Biotin carboxylase
AN935_12040	COG0511	ligase activity, forming carbon-carbon bonds
AN935_12080	COG3854	ATPases associated with a variety of cellular activities
AN935_12090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AN935_12095	COG0006	proline dipeptidase activity
AN935_12100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AN935_12110	COG3872	metal-dependent enzyme
AN935_12120	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN935_12125	COG1321	iron dependent repressor
AN935_12130	COG0095	Lipoate-protein ligase
AN935_12135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN935_12140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN935_12145	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN935_12150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AN935_12155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AN935_12170	COG1396	sequence-specific DNA binding
AN935_12180	COG0681	Belongs to the peptidase S26 family
AN935_12205	COG4940	Competence protein ComGF
AN935_12215	COG4970	Tfp pilus assembly protein FimT
AN935_12220	COG4537	Required for transformation and DNA binding
AN935_12225	COG1459	type II secretion system
AN935_12230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN935_12240	COG0517	IMP dehydrogenase activity
AN935_12245	COG0598	Magnesium transport protein CorA
AN935_12250	COG1253	flavin adenine dinucleotide binding
AN935_12255	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_12265	COG1393	Belongs to the ArsC family
AN935_12275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_12285	COG0011	TIGRFAM Protein of
AN935_12295	COG2866	Carboxypeptidase
AN935_12300	COG1368	sulfuric ester hydrolase activity
AN935_12305	COG1940	carbohydrate kinase activity
AN935_12310	COG4483	Protein conserved in bacteria
AN935_12315	COG0457	Tetratricopeptide repeat
AN935_12315	COG0705	Rhomboid family
AN935_12325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AN935_12335	COG0438	transferase activity, transferring glycosyl groups
AN935_12350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN935_12355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN935_12360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN935_12365	COG0581	inorganic phosphate transmembrane transporter activity
AN935_12370	COG0573	inorganic phosphate transmembrane transporter activity
AN935_12375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AN935_12380	COG0768	penicillin binding
AN935_12385	COG0477	Major facilitator Superfamily
AN935_12390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AN935_12395	COG2839	Protein conserved in bacteria
AN935_12400	COG5521	maltodextrose utilization protein MalA
AN935_12405	COG1388	LysM domain
AN935_12410	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AN935_12415	COG4709	membrane
AN935_12420	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AN935_12425	COG0735	belongs to the Fur family
AN935_12430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_12440	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AN935_12445	COG0513	Belongs to the DEAD box helicase family
AN935_12455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AN935_12460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AN935_12465	COG2384	SAM-dependent methyltransferase
AN935_12470	COG2010	Cytochrome c
AN935_12475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AN935_12480	COG0358	DNA primase activity
AN935_12485	COG1671	Belongs to the UPF0178 family
AN935_12490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AN935_12495	COG0517	IMP dehydrogenase activity
AN935_12500	COG0751	glycine-tRNA ligase activity
AN935_12505	COG0752	glycyl-tRNA synthetase alpha subunit
AN935_12510	COG1381	Involved in DNA repair and RecF pathway recombination
AN935_12520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN935_12525	COG0295	cytidine deaminase activity
AN935_12530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AN935_12535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AN935_12540	COG1480	7TM receptor with intracellular HD hydrolase
AN935_12550	COG1702	phosphate starvation-inducible protein PhoH
AN935_12555	COG0561	phosphatase activity
AN935_12570	COG4864	UPF0365 protein
AN935_12575	COG1030	water channel activity
AN935_12580	COG1610	YqeY-like protein
AN935_12590	COG1283	sodium-dependent phosphate transmembrane transporter activity
AN935_12595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AN935_12600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN935_12605	COG2264	protein methyltransferase activity
AN935_12620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AN935_12625	COG1420	regulation of RNA biosynthetic process
AN935_12630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN935_12635	COG0481	GTPase activity
AN935_12645	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_12650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AN935_12655	COG0268	Binds directly to 16S ribosomal RNA
AN935_12660	COG1466	dna polymerase III delta subunit
AN935_12670	COG2333	competence protein COMEC
AN935_12670	COG0658	competence protein
AN935_12675	COG2131	deaminase
AN935_12680	COG1596	polysaccharide export
AN935_12680	COG1555	photosystem II stabilization
AN935_12685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN935_12690	COG2226	methyltransferase
AN935_12695	COG0799	negative regulation of ribosome biogenesis
AN935_12700	COG1713	HD superfamily hydrolase involved in NAD metabolism
AN935_12705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AN935_12710	COG1534	Rna-binding protein
AN935_12715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AN935_12720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AN935_12725	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AN935_12735	COG2755	lipolytic protein G-D-S-L family
AN935_12740	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN935_12740	COG3409	Peptidoglycan-binding domain 1 protein
AN935_12745	COG0398	Pfam SNARE associated Golgi protein
AN935_12750	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AN935_12760	COG3209	COG3209 Rhs family protein
AN935_12775	COG2814	Major facilitator Superfamily
AN935_12780	COG2814	Major facilitator Superfamily
AN935_12785	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AN935_12790	COG1335	isochorismatase
AN935_12795	COG1522	sequence-specific DNA binding
AN935_12800	COG1522	sequence-specific DNA binding
AN935_12805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_12810	COG0730	response to heat
AN935_12815	COG0425	Belongs to the sulfur carrier protein TusA family
AN935_12820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_12820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN935_12830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN935_12830	COG0425	Belongs to the sulfur carrier protein TusA family
AN935_12840	COG2210	Belongs to the sulfur carrier protein TusA family
AN935_12845	COG1937	Protein conserved in bacteria
AN935_12865	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_12870	COG1309	transcriptional regulator
AN935_12875	COG2085	NADP oxidoreductase coenzyme F420-dependent
AN935_12880	COG1733	regulation of RNA biosynthetic process
AN935_12900	COG0457	Tetratricopeptide repeat
AN935_12910	COG5444	nuclease activity
AN935_12915	COG4282	regulation of fungal-type cell wall biogenesis
AN935_12925	COG2732	(Barnase) inhibitor
AN935_12940	COG4824	toxin secretion phage lysis holin
AN935_12965	COG0563	adenylate kinase activity
AN935_12985	COG0697	spore germination
AN935_12990	COG0583	DNA-binding transcription factor activity
AN935_12995	COG4124	Belongs to the glycosyl hydrolase 26 family
AN935_13000	COG0697	spore germination
AN935_13005	COG2207	Transcriptional regulator
AN935_13005	COG1917	Cupin 2, conserved barrel domain protein
AN935_13010	COG0697	spore germination
AN935_13015	COG1802	Transcriptional regulator
AN935_13020	COG2318	DinB family
AN935_13025	COG0456	acetyltransferase
AN935_13030	COG0477	Major facilitator Superfamily
AN935_13035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_13045	COG0747	negative chemotaxis
AN935_13050	COG0601	transmembrane transport
AN935_13055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN935_13060	COG0444	Belongs to the ABC transporter superfamily
AN935_13065	COG4608	Belongs to the ABC transporter superfamily
AN935_13070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN935_13080	COG3443	Belongs to the bacterial solute-binding protein 9 family
AN935_13085	COG1595	DNA-templated transcription, initiation
AN935_13090	COG0667	Aldo Keto reductase
AN935_13095	COG3409	Peptidoglycan-binding domain 1 protein
AN935_13100	COG5566	PFAM Mor transcription activator
AN935_13105	COG0596	Alpha beta hydrolase
AN935_13110	COG0697	spore germination
AN935_13115	COG0110	maltose O-acetyltransferase activity
AN935_13120	COG4991	sh3 domain protein
AN935_13125	COG4991	sh3 domain protein
AN935_13135	COG5577	PFAM Coat F domain
AN935_13140	COG1063	alcohol dehydrogenase
AN935_13150	COG5577	PFAM Coat F domain
AN935_13160	COG0667	Aldo Keto reductase
AN935_13165	COG2207	Transcriptional regulator
AN935_13170	COG0789	Transcriptional regulator
AN935_13175	COG0789	Transcriptional regulator
AN935_13180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN935_13185	COG1064	alcohol dehydrogenase
AN935_13190	COG0693	protein deglycase activity
AN935_13195	COG1621	beta-fructofuranosidase activity
AN935_13200	COG3716	PTS system mannose fructose sorbose family IID component
AN935_13205	COG3715	PTS system
AN935_13210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_13215	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_13220	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AN935_13220	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AN935_13230	COG1113	amino acid transport
AN935_13235	COG1280	lysine exporter protein (LysE YggA)
AN935_13240	COG1378	Sugar-specific transcriptional regulator TrmB
AN935_13245	COG1595	DNA-templated transcription, initiation
AN935_13255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AN935_13255	COG2755	lipolytic protein G-D-S-L family
AN935_13265	COG2124	cytochrome p450
AN935_13265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN935_13270	COG1309	transcriptional regulator
AN935_13275	COG2226	methyltransferase
AN935_13285	COG2116	formate transmembrane transporter activity
AN935_13290	COG5609	conserved protein (DUF2294)
AN935_13295	COG3383	formate dehydrogenase (NAD+) activity
AN935_13300	COG2427	Protein of unknown function (DUF1641)
AN935_13310	COG0626	cystathionine gamma-synthase activity
AN935_13315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN935_13320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AN935_13325	COG2226	methyltransferase
AN935_13340	COG0768	penicillin binding
AN935_13345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN935_13350	COG0572	uridine kinase
AN935_13355	COG0826	peptidase U32
AN935_13360	COG0826	peptidase U32
AN935_13365	COG4122	O-methyltransferase activity
AN935_13370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN935_13375	COG3906	Belongs to the UPF0473 family
AN935_13380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AN935_13385	COG4472	Bacterial protein of unknown function (DUF965)
AN935_13390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AN935_13395	COG0628	permease
AN935_13400	COG1126	abc transporter atp-binding protein
AN935_13405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_13410	COG0765	amino acid transport
AN935_13415	COG0765	amino acid transport
AN935_13430	COG3881	PFAM PRC-barrel domain
AN935_13435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN935_13440	COG0457	Tetratricopeptide repeat
AN935_13445	COG0482	sulfurtransferase activity
AN935_13450	COG1104	cysteine desulfurase activity
AN935_13455	COG1959	2 iron, 2 sulfur cluster binding
AN935_13460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AN935_13465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AN935_13475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AN935_13480	COG0124	histidyl-tRNA synthetase
AN935_13490	COG4991	sh3 domain protein
AN935_13490	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_13490	COG3103	Sh3 type 3 domain protein
AN935_13495	COG1490	D-aminoacyl-tRNA deacylase activity
AN935_13500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN935_13505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN935_13510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AN935_13510	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AN935_13515	COG5416	Lipopolysaccharide assembly protein A domain
AN935_13520	COG0490	domain, Protein
AN935_13525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN935_13525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN935_13535	COG2244	polysaccharide biosynthetic process
AN935_13540	COG2323	membrane
AN935_13550	COG1862	Preprotein translocase
AN935_13555	COG0343	queuine tRNA-ribosyltransferase activity
AN935_13560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AN935_13570	COG2255	four-way junction helicase activity
AN935_13575	COG0632	four-way junction helicase activity
AN935_13585	COG2814	Major facilitator Superfamily
AN935_13590	COG0673	inositol 2-dehydrogenase activity
AN935_13595	COG2112	serine threonine protein kinase
AN935_13615	COG1115	amino acid carrier protein
AN935_13620	COG0217	transcriptional regulatory protein
AN935_13630	COG1388	LysM domain
AN935_13635	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AN935_13640	COG0157	Belongs to the NadC ModD family
AN935_13645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AN935_13650	COG1104	cysteine desulfurase activity
AN935_13655	COG1827	regulation of RNA biosynthetic process
AN935_13660	COG0077	Prephenate dehydratase
AN935_13665	COG4492	Belongs to the UPF0735 family
AN935_13670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AN935_13675	COG3290	protein histidine kinase activity
AN935_13685	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AN935_13690	COG2868	ribosomal protein
AN935_13695	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AN935_13700	COG1994	Peptidase M50
AN935_13705	COG0739	heme binding
AN935_13710	COG2894	cell division
AN935_13715	COG0850	regulation of cytokinetic process
AN935_13720	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AN935_13730	COG1077	Cell shape determining protein MreB Mrl
AN935_13770	COG0457	Tetratricopeptide repeat
AN935_13775	COG5444	nuclease activity
AN935_13785	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN935_13785	COG1388	LysM domain
AN935_13785	COG3409	Peptidoglycan-binding domain 1 protein
AN935_13820	COG1705	Flagellar rod assembly protein muramidase FlgJ
AN935_13830	COG3953	SLT domain
AN935_13830	COG5280	Phage tail tape measure protein TP901
AN935_14005	COG0424	maF-like protein
AN935_14015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AN935_14020	COG0285	dihydrofolate synthase activity
AN935_14025	COG0525	valine-tRNA ligase activity
AN935_14035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN935_14040	COG1388	LysM domain
AN935_14045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AN935_14050	COG0113	porphobilinogen synthase activity
AN935_14055	COG1587	Uroporphyrinogen-III synthase
AN935_14060	COG0181	hydroxymethylbilane synthase activity
AN935_14065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN935_14070	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AN935_14080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AN935_14085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AN935_14090	COG0470	DNA polymerase III
AN935_14090	COG1067	ATP-dependent peptidase activity
AN935_14095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AN935_14100	COG0544	peptidyl-prolyl cis-trans isomerase activity
AN935_14105	COG1477	protein flavinylation
AN935_14105	COG0457	Tetratricopeptide repeat
AN935_14110	COG0066	3-isopropylmalate dehydratase activity
AN935_14115	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AN935_14120	COG0473	3-isopropylmalate dehydrogenase activity
AN935_14125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN935_14130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AN935_14135	COG0440	acetolactate synthase activity
AN935_14140	COG0028	Belongs to the TPP enzyme family
AN935_14150	COG0454	-acetyltransferase
AN935_14155	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AN935_14165	COG0622	Phosphoesterase
AN935_14170	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AN935_14175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AN935_14180	COG5401	PFAM Sporulation and spore germination
AN935_14185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN935_14190	COG1846	Transcriptional regulator
AN935_14195	COG2197	response regulator
AN935_14200	COG0824	Thioesterase
AN935_14205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AN935_14210	COG1053	succinate dehydrogenase
AN935_14215	COG2009	succinate dehydrogenase
AN935_14225	COG1719	4-vinyl reductase, 4VR
AN935_14230	COG0527	aspartate kinase activity
AN935_14235	COG0322	excinuclease ABC activity
AN935_14240	COG3118	belongs to the thioredoxin family
AN935_14245	COG3534	alpha-L-arabinofuranosidase
AN935_14250	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AN935_14255	COG2086	electron transfer activity
AN935_14260	COG1024	Enoyl-CoA hydratase
AN935_14265	COG1309	transcriptional regulator
AN935_14270	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_14275	COG3766	membrane
AN935_14280	COG1193	negative regulation of DNA recombination
AN935_14285	COG1796	DNA polymerase
AN935_14285	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AN935_14290	COG1286	toxin biosynthetic process
AN935_14295	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AN935_14300	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN935_14305	COG0072	phenylalanine-tRNA ligase activity
AN935_14305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_14310	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AN935_14320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN935_14330	COG3835	regulator
AN935_14335	COG0277	FAD linked oxidase domain protein
AN935_14340	COG0247	lactate metabolic process
AN935_14345	COG0346	lactoylglutathione lyase activity
AN935_14350	COG1966	Carbon starvation protein
AN935_14365	COG1695	Transcriptional regulator
AN935_14370	COG3534	alpha-L-arabinofuranosidase
AN935_14375	COG0395	ABC-type sugar transport system, permease component
AN935_14380	COG1175	transmembrane transport
AN935_14385	COG1653	transport
AN935_14390	COG0371	Dehydrogenase
AN935_14395	COG0647	UMP catabolic process
AN935_14400	COG0235	Class ii aldolase
AN935_14405	COG1069	ribulokinase activity
AN935_14410	COG2160	L-arabinose isomerase activity
AN935_14415	COG3507	Belongs to the glycosyl hydrolase 43 family
AN935_14420	COG1363	Peptidase, m42
AN935_14430	COG3326	Membrane
AN935_14435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AN935_14440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AN935_14445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AN935_14455	COG1346	cytolysis
AN935_14460	COG1380	Effector of murein hydrolase LrgA
AN935_14465	COG3279	Response regulator of the LytR AlgR family
AN935_14470	COG3275	phosphorelay sensor kinase activity
AN935_14475	COG1011	Hydrolase
AN935_14480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN935_14490	COG0398	Pfam SNARE associated Golgi protein
AN935_14495	COG1484	DNA-dependent DNA replication
AN935_14500	COG3611	Membrane attachment protein
AN935_14505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AN935_14510	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AN935_14515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN935_14520	COG1733	regulation of RNA biosynthetic process
AN935_14525	COG2814	Major facilitator Superfamily
AN935_14530	COG0656	L-ascorbic acid biosynthetic process
AN935_14535	COG0237	dephospho-CoA kinase activity
AN935_14550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AN935_14555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN935_14555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN935_14560	COG5002	protein histidine kinase activity
AN935_14565	COG0745	RESPONSE REGULATOR receiver
AN935_14570	COG0039	L-malate dehydrogenase activity
AN935_14575	COG0538	isocitrate dehydrogenase activity
AN935_14580	COG0372	Belongs to the citrate synthase family
AN935_14585	COG2707	UPF0756 membrane protein
AN935_14590	COG0628	permease
AN935_14595	COG3030	protein affecting phage T7 exclusion by the F plasmid
AN935_14600	COG0469	pyruvate kinase activity
AN935_14605	COG0205	6-phosphofructokinase activity
AN935_14610	COG0825	malonyl-CoA metabolic process
AN935_14615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AN935_14620	COG0281	malic enzyme
AN935_14625	COG0587	DNA-directed DNA polymerase activity
AN935_14645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AN935_14655	COG4109	DRTGG domain
AN935_14665	COG0730	response to heat
AN935_14670	COG1473	amidohydrolase
AN935_14675	COG0196	riboflavin kinase activity
AN935_14680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_14685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN935_14690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_14695	COG1126	abc transporter atp-binding protein
AN935_14700	COG0765	amino acid transport
AN935_14705	COG0765	amino acid transport
AN935_14710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_14715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_14720	COG0454	-acetyltransferase
AN935_14725	COG0583	DNA-binding transcription factor activity
AN935_14730	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AN935_14735	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_14745	COG0165	Argininosuccinate lyase
AN935_14750	COG0137	argininosuccinate synthase activity
AN935_14755	COG0521	Mo-molybdopterin cofactor biosynthetic process
AN935_14760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN935_14765	COG0827	DNA restriction-modification system
AN935_14770	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AN935_14775	COG3874	Sporulation protein YtfJ
AN935_14785	COG1714	RDD family
AN935_14790	COG0616	signal peptide processing
AN935_14795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN935_14800	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AN935_14805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN935_14815	COG0301	tRNA thio-modification
AN935_14820	COG1104	cysteine desulfurase activity
AN935_14825	COG1114	Component of the transport system for branched-chain amino acids
AN935_14830	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AN935_14835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AN935_14840	COG1309	transcriptional regulator
AN935_14845	COG1956	GAF domain-containing protein
AN935_14850	COG2199	diguanylate cyclase activity
AN935_14850	COG2203	Gaf domain
AN935_14855	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AN935_14865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AN935_14870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN935_14875	COG0454	-acetyltransferase
AN935_14880	COG0517	IMP dehydrogenase activity
AN935_14885	COG0123	including yeast histone deacetylase and acetoin utilization protein
AN935_14890	COG1360	Flagellar Motor Protein
AN935_14895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AN935_14900	COG1609	Transcriptional regulator
AN935_14905	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AN935_14905	COG1605	Chorismate mutase
AN935_14910	COG3118	belongs to the thioredoxin family
AN935_14915	COG4980	gas vesicle protein
AN935_14920	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AN935_14925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN935_14930	COG1674	ftsk spoiiie
AN935_14935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_14940	COG4848	Belongs to the UPF0354 family
AN935_14945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_14955	COG1363	Peptidase, m42
AN935_14960	COG5584	Small secreted protein
AN935_14965	COG0281	malic enzyme
AN935_14970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_14975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AN935_14985	COG0510	thiamine kinase activity
AN935_14990	COG1523	belongs to the glycosyl hydrolase 13 family
AN935_14995	COG1597	lipid kinase activity
AN935_15005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AN935_15010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN935_15015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN935_15020	COG2252	PERMEase
AN935_15025	COG4473	ABC transporter
AN935_15030	COG1131	(ABC) transporter
AN935_15035	COG1349	DNA-binding transcription factor activity
AN935_15040	COG1187	pseudouridine synthase activity
AN935_15045	COG2244	polysaccharide biosynthetic process
AN935_15050	COG2081	HI0933 family
AN935_15055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN935_15065	COG5578	integral membrane protein
AN935_15070	COG0673	inositol 2-dehydrogenase activity
AN935_15075	COG1653	transport
AN935_15080	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AN935_15085	COG4209	transmembrane transport
AN935_15090	COG2207	Transcriptional regulator
AN935_15095	COG1653	transport
AN935_15100	COG0395	ABC-type sugar transport system, permease component
AN935_15105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN935_15110	COG2124	cytochrome p450
AN935_15115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AN935_15125	COG0156	8-amino-7-oxononanoate synthase activity
AN935_15130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AN935_15135	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AN935_15145	COG1073	alpha beta
AN935_15150	COG1609	Transcriptional regulator
AN935_15155	COG1653	transport
AN935_15160	COG1175	transmembrane transport
AN935_15165	COG0395	ABC-type sugar transport system, permease component
AN935_15170	COG1486	melibiose metabolic process
AN935_15175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN935_15180	COG0495	leucyl-tRNA aminoacylation
AN935_15190	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_15190	COG2202	Pas domain
AN935_15195	COG2814	Major facilitator Superfamily
AN935_15200	COG2433	Pfam Transposase IS66
AN935_15205	COG0577	efflux transmembrane transporter activity
AN935_15210	COG1136	(ABC) transporter
AN935_15215	COG2205	protein histidine kinase activity
AN935_15220	COG0745	RESPONSE REGULATOR receiver
AN935_15225	COG0577	efflux transmembrane transporter activity
AN935_15230	COG1136	(ABC) transporter
AN935_15245	COG1131	(ABC) transporter
AN935_15250	COG1725	Transcriptional regulator
AN935_15265	COG1242	4 iron, 4 sulfur cluster binding
AN935_15270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AN935_15280	COG2267	carboxylic ester hydrolase activity
AN935_15285	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AN935_15290	COG1113	amino acid transport
AN935_15295	COG0367	asparagine synthase
AN935_15300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AN935_15305	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AN935_15315	COG1506	peptidase
AN935_15320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN935_15325	COG1116	anion transmembrane transporter activity
AN935_15330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN935_15335	COG0494	nUDIX hydrolase
AN935_15340	COG4824	toxin secretion phage lysis holin
AN935_15345	COG0783	Belongs to the Dps family
AN935_15360	COG1854	S-ribosylhomocysteine lyase activity
AN935_15365	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AN935_15370	COG0288	reversible hydration of carbon dioxide
AN935_15375	COG0254	rRNA binding
AN935_15380	COG1271	oxidase subunit
AN935_15385	COG1294	oxidase, subunit
AN935_15395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN935_15400	COG1321	iron dependent repressor
AN935_15400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN935_15405	COG1121	(ABC) transporter
AN935_15410	COG0803	Belongs to the bacterial solute-binding protein 9 family
AN935_15415	COG4948	Mandelate Racemase Muconate Lactonizing
AN935_15420	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_15425	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AN935_15430	COG0596	Alpha beta hydrolase
AN935_15435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AN935_15440	COG1169	isochorismate synthase
AN935_15445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN935_15450	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AN935_15455	COG0058	SHG alpha-glucan phosphorylase activity
AN935_15460	COG0297	glycogen (starch) synthase activity
AN935_15465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AN935_15470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AN935_15475	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AN935_15525	COG3859	Proton-coupled thiamine transporter YuaJ
AN935_15530	COG1247	-acetyltransferase
AN935_15535	COG2268	Band 7 protein
AN935_15540	COG1585	Membrane protein implicated in regulation of membrane protease activity
AN935_15545	COG2318	DinB family
AN935_15555	COG1454	alcohol dehydrogenase
AN935_15560	COG1012	belongs to the aldehyde dehydrogenase family
AN935_15565	COG1510	regulation of RNA biosynthetic process
AN935_15575	COG0569	domain protein
AN935_15580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN935_15585	COG4682	membrane
AN935_15590	COG1705	Flagellar rod assembly protein muramidase FlgJ
AN935_15595	COG0477	Major facilitator Superfamily
AN935_15600	COG5553	Cysteine dioxygenase type I
AN935_15610	COG1968	undecaprenyl-diphosphatase activity
AN935_15615	COG0628	permease
AN935_15620	COG0673	inositol 2-dehydrogenase activity
AN935_15625	COG4806	L-rhamnose isomerase
AN935_15630	COG3254	rhamnose metabolic process
AN935_15635	COG1070	Carbohydrate kinase
AN935_15640	COG1349	DNA-binding transcription factor activity
AN935_15645	COG3347	Dehydrogenase
AN935_15645	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_15650	COG0840	transmembrane signaling receptor activity
AN935_15655	COG0840	transmembrane signaling receptor activity
AN935_15665	COG0840	transmembrane signaling receptor activity
AN935_15680	COG2070	2-Nitropropane dioxygenase
AN935_15685	COG0432	Pfam Uncharacterised protein family UPF0047
AN935_15690	COG0366	Alpha amylase catalytic
AN935_15695	COG1253	flavin adenine dinucleotide binding
AN935_15700	COG2738	Putative neutral zinc metallopeptidase
AN935_15715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN935_15730	COG0166	Belongs to the GPI family
AN935_15735	COG1979	alcohol dehydrogenase
AN935_15740	COG1979	alcohol dehydrogenase
AN935_15745	COG2155	Conserved Protein
AN935_15750	COG1098	S1 RNA binding domain
AN935_15755	COG0436	Aminotransferase
AN935_15760	COG1522	sequence-specific DNA binding
AN935_15765	COG2267	carboxylic ester hydrolase activity
AN935_15775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AN935_15780	COG2205	protein histidine kinase activity
AN935_15790	COG5018	Exonuclease
AN935_15800	COG2814	Major facilitator Superfamily
AN935_15805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN935_15810	COG3011	Protein conserved in bacteria
AN935_15820	COG3290	protein histidine kinase activity
AN935_15825	COG4565	transcriptional regulatory protein
AN935_15830	COG1744	ABC transporter substrate-binding protein PnrA-like
AN935_15835	COG3845	ABC transporter
AN935_15840	COG4603	Belongs to the binding-protein-dependent transport system permease family
AN935_15845	COG1079	Belongs to the binding-protein-dependent transport system permease family
AN935_15850	COG3493	citrate carrier protein
AN935_15860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN935_15860	COG2111	Na H antiporter
AN935_15865	COG2111	Na H antiporter
AN935_15870	COG1006	Multisubunit Na H antiporter MnhC subunit
AN935_15875	COG0651	ATP synthesis coupled electron transport
AN935_15880	COG1863	multisubunit Na H antiporter MnhE subunit
AN935_15885	COG2212	antiporter activity
AN935_15890	COG1320	monovalent cation:proton antiporter activity
AN935_15895	COG2050	protein possibly involved in aromatic compounds catabolism
AN935_15900	COG2197	response regulator
AN935_15905	COG4585	Histidine kinase
AN935_15915	COG0142	geranyltranstransferase activity
AN935_15930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AN935_15935	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AN935_15940	COG1335	isochorismatase
AN935_15945	COG5506	Protein of unknown function (DUF1694)
AN935_15960	COG0628	permease
AN935_15975	COG1418	mRNA catabolic process
AN935_15980	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_15990	COG1511	domain protein
AN935_15995	COG0433	COG0433 Predicted ATPase
AN935_15995	COG1674	ftsk spoiiie
AN935_16000	COG4499	WXG100 protein secretion system (Wss), protein YukC
AN935_16005	COG5417	Belongs to the EsaB family
AN935_16010	COG4842	Belongs to the WXG100 family
AN935_16015	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AN935_16015	COG2508	Transcriptional regulator
AN935_16020	COG0686	Belongs to the AlaDH PNT family
AN935_16025	COG5634	Uncharacterized conserved protein (DUF2278)
AN935_16030	COG3251	PFAM MbtH domain protein
AN935_16035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_16040	COG3433	isochorismatase activity
AN935_16040	COG1535	isochorismatase
AN935_16045	COG1021	2,3-dihydroxybenzoate-AMP ligase
AN935_16050	COG1169	isochorismate synthase
AN935_16055	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_16060	COG2819	hydrolase of the alpha beta superfamily
AN935_16065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AN935_16070	COG1268	BioY protein
AN935_16075	COG2056	Na+-H+ antiporter family
AN935_16080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AN935_16085	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AN935_16090	COG3584	3D domain protein
AN935_16105	COG1252	NADH dehydrogenase
AN935_16110	COG0492	ferredoxin-NADP+ reductase activity
AN935_16120	COG0516	GMP reductase activity
AN935_16125	COG2808	Putative FMN-binding domain
AN935_16130	COG0456	acetyltransferase
AN935_16135	COG0316	Belongs to the HesB IscA family
AN935_16140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AN935_16145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN935_16150	COG4844	belongs to the
AN935_16155	COG1252	NADH dehydrogenase
AN935_16160	COG4837	Protein of unknown function (DUF1462)
AN935_16165	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AN935_16170	COG4946	Tricorn protease homolog
AN935_16170	COG0823	Involved in the tonB-independent uptake of proteins
AN935_16170	COG1506	peptidase
AN935_16175	COG0083	homoserine kinase activity
AN935_16180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AN935_16185	COG0460	homoserine dehydrogenase
AN935_16190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN935_16195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AN935_16200	COG0647	UMP catabolic process
AN935_16205	COG2445	Protein of unknown function DUF86
AN935_16210	COG4470	Protein conserved in bacteria
AN935_16220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AN935_16225	COG0739	heme binding
AN935_16235	COG3377	Domain of unknown function (DUF1805)
AN935_16240	COG0737	Belongs to the 5'-nucleotidase family
AN935_16245	COG0730	response to heat
AN935_16250	COG1801	Protein of unknown function DUF72
AN935_16260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AN935_16265	COG2508	Transcriptional regulator
AN935_16270	COG2233	PERMEase
AN935_16275	COG2233	PERMEase
AN935_16280	COG3648	Uricase
AN935_16280	COG3195	allantoin biosynthetic process
AN935_16285	COG2351	hydroxyisourate hydrolase activity
AN935_16300	COG2080	2 iron, 2 sulfur cluster binding
AN935_16305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AN935_16310	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AN935_16315	COG2068	MobA-Related Protein
AN935_16320	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AN935_16325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AN935_16330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN935_16340	COG2356	endonuclease I
AN935_16345	COG3842	ATPase activity
AN935_16350	COG2188	Transcriptional regulator
AN935_16355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_16360	COG0395	ABC-type sugar transport system, permease component
AN935_16365	COG1175	transmembrane transport
AN935_16370	COG1653	transport
AN935_16375	COG2222	sugar isomerase
AN935_16380	COG0322	excinuclease ABC activity
AN935_16385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN935_16405	COG0640	Transcriptional regulator
AN935_16410	COG0719	Fe-S assembly protein
AN935_16415	COG0822	iron-sulfur transferase activity
AN935_16420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN935_16425	COG0719	Fe-S assembly protein
AN935_16430	COG0396	ATPase activity
AN935_16440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN935_16445	COG1464	Belongs to the NlpA lipoprotein family
AN935_16450	COG2011	ABC-type metal ion transport system permease component
AN935_16455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN935_16465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_16470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AN935_16480	COG0509	glycine decarboxylation via glycine cleavage system
AN935_16485	COG1393	Belongs to the ArsC family
AN935_16490	COG1960	acyl-CoA dehydrogenase activity
AN935_16495	COG0183	Belongs to the thiolase family
AN935_16500	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN935_16500	COG1024	Enoyl-CoA hydratase
AN935_16510	COG0506	proline dehydrogenase activity
AN935_16520	COG5577	PFAM Coat F domain
AN935_16525	COG1846	Transcriptional regulator
AN935_16530	COG0477	Major facilitator Superfamily
AN935_16535	COG1942	4-Oxalocrotonate Tautomerase
AN935_16540	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_16545	COG0583	DNA-binding transcription factor activity
AN935_16555	COG1120	ATPase activity
AN935_16570	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_16575	COG0783	Belongs to the Dps family
AN935_16580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN935_16585	COG0745	RESPONSE REGULATOR receiver
AN935_16590	COG2770	Histidine kinase
AN935_16590	COG2205	protein histidine kinase activity
AN935_16600	COG1309	transcriptional regulator
AN935_16605	COG0114	fumarate hydratase activity
AN935_16615	COG0697	spore germination
AN935_16620	COG0814	amino acid
AN935_16630	COG2197	response regulator
AN935_16635	COG4585	Histidine kinase
AN935_16640	COG4758	membrane
AN935_16645	COG3595	metallopeptidase activity
AN935_16650	COG1842	Phage shock protein A
AN935_16655	COG4758	membrane
AN935_16660	COG2814	Major facilitator Superfamily
AN935_16665	COG2096	Adenosyltransferase
AN935_16670	COG1120	ATPase activity
AN935_16675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_16680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_16685	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_16690	COG3386	PFAM SMP-30 Gluconolaconase
AN935_16695	COG2205	protein histidine kinase activity
AN935_16700	COG0745	RESPONSE REGULATOR receiver
AN935_16710	COG1191	sigma factor activity
AN935_16720	COG2140	Oxalate decarboxylase
AN935_16730	COG0577	efflux transmembrane transporter activity
AN935_16735	COG1136	(ABC) transporter
AN935_16740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN935_16745	COG1120	ATPase activity
AN935_16750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_16755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_16760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_16765	COG0640	Transcriptional regulator
AN935_16780	COG0531	amino acid
AN935_16790	COG1988	membrane-bound metal-dependent
AN935_16795	COG1368	sulfuric ester hydrolase activity
AN935_16800	COG1910	domain protein
AN935_16805	COG0725	ABC transporter, periplasmic molybdate-binding protein
AN935_16810	COG4149	molybdate abc transporter
AN935_16815	COG0656	L-ascorbic acid biosynthetic process
AN935_16825	COG0025	NhaP-type Na H and K H
AN935_16830	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN935_16835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN935_16840	COG3973	AAA domain
AN935_16845	COG2860	membrane
AN935_16850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AN935_16855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN935_16860	COG2217	Heavy metal translocating P-type atpase
AN935_16865	COG2217	Heavy metal translocating P-type atpase
AN935_16870	COG2608	mercury ion transmembrane transporter activity
AN935_16875	COG1937	Protein conserved in bacteria
AN935_16880	COG0673	inositol 2-dehydrogenase activity
AN935_16885	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AN935_16890	COG1289	transmembrane transporter activity
AN935_16905	COG2076	Multidrug Resistance protein
AN935_16910	COG1309	transcriptional regulator
AN935_16915	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_16935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AN935_16940	COG0557	exoribonuclease II activity
AN935_16945	COG1647	Serine aminopeptidase, S33
AN935_16950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN935_16955	COG0596	Alpha beta hydrolase
AN935_16960	COG1476	TRANSCRIPTIONal
AN935_16965	COG1396	sequence-specific DNA binding
AN935_16970	COG1396	sequence-specific DNA binding
AN935_16975	COG1733	regulation of RNA biosynthetic process
AN935_16980	COG0840	transmembrane signaling receptor activity
AN935_16985	COG1174	glycine betaine transport
AN935_16990	COG1732	Glycine betaine
AN935_16995	COG1174	glycine betaine transport
AN935_17000	COG1125	glycine betaine transport
AN935_17000	COG0517	IMP dehydrogenase activity
AN935_17005	COG1510	regulation of RNA biosynthetic process
AN935_17010	COG1174	glycine betaine transport
AN935_17015	COG1732	Glycine betaine
AN935_17020	COG1174	glycine betaine transport
AN935_17025	COG0517	IMP dehydrogenase activity
AN935_17025	COG1125	glycine betaine transport
AN935_17030	COG1510	regulation of RNA biosynthetic process
AN935_17040	COG3064	Membrane
AN935_17045	COG4640	response to antibiotic
AN935_17050	COG0456	acetyltransferase
AN935_17060	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AN935_17070	COG0126	phosphoglycerate kinase activity
AN935_17080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN935_17085	COG2390	Transcriptional regulator
AN935_17090	COG2814	Major facilitator Superfamily
AN935_17095	COG1609	Transcriptional regulator
AN935_17100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_17105	COG0583	DNA-binding transcription factor activity
AN935_17110	COG0697	spore germination
AN935_17115	COG1113	amino acid transport
AN935_17120	COG3858	chitin binding
AN935_17125	COG1556	Lactate utilization protein
AN935_17130	COG1139	Iron-sulfur cluster binding protein
AN935_17135	COG0247	lactate metabolic process
AN935_17140	COG2197	response regulator
AN935_17145	COG4585	Histidine kinase
AN935_17150	COG0842	Transport permease protein
AN935_17155	COG1131	(ABC) transporter
AN935_17160	COG0596	Alpha beta hydrolase
AN935_17165	COG2208	phosphoserine phosphatase activity
AN935_17170	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AN935_17175	COG1874	Beta-galactosidase
AN935_17180	COG3833	ABC-type maltose transport systems, permease component
AN935_17185	COG1175	transmembrane transport
AN935_17190	COG2182	Extracellular solute-binding protein
AN935_17195	COG1609	Transcriptional regulator
AN935_17200	COG2186	Transcriptional regulator
AN935_17205	COG1620	l-lactate permease
AN935_17210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AN935_17220	COG5039	Polysaccharide pyruvyl transferase
AN935_17225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN935_17230	COG0110	maltose O-acetyltransferase activity
AN935_17235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AN935_17240	COG2244	polysaccharide biosynthetic process
AN935_17245	COG1216	Glycosyl transferase, family 2
AN935_17250	COG5039	Polysaccharide pyruvyl transferase
AN935_17255	COG1216	Glycosyl transferase, family 2
AN935_17265	COG0438	transferase activity, transferring glycosyl groups
AN935_17270	COG1215	transferase activity, transferring glycosyl groups
AN935_17275	COG0438	transferase activity, transferring glycosyl groups
AN935_17280	COG1086	Polysaccharide biosynthesis protein
AN935_17285	COG0489	protein tyrosine kinase activity
AN935_17290	COG3944	biosynthesis protein
AN935_17295	COG1396	sequence-specific DNA binding
AN935_17300	COG2272	Belongs to the type-B carboxylesterase lipase family
AN935_17310	COG3479	Phenolic acid decarboxylase
AN935_17320	COG1794	racemase activity, acting on amino acids and derivatives
AN935_17325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN935_17335	COG1621	beta-fructofuranosidase activity
AN935_17340	COG1621	beta-fructofuranosidase activity
AN935_17345	COG0531	amino acid
AN935_17350	COG1309	transcriptional regulator
AN935_17355	COG2076	Multidrug Resistance protein
AN935_17360	COG2076	Multidrug Resistance protein
AN935_17380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN935_17385	COG0366	Alpha amylase catalytic
AN935_17390	COG1554	hydrolase, family 65, central catalytic
AN935_17400	COG3833	ABC-type maltose transport systems, permease component
AN935_17405	COG1175	transmembrane transport
AN935_17410	COG2182	Extracellular solute-binding protein
AN935_17415	COG0366	Alpha amylase catalytic
AN935_17420	COG1609	Transcriptional regulator
AN935_17425	COG1611	Belongs to the LOG family
AN935_17430	COG1694	Mazg nucleotide pyrophosphohydrolase
AN935_17440	COG0288	reversible hydration of carbon dioxide
AN935_17445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN935_17450	COG0577	efflux transmembrane transporter activity
AN935_17455	COG1136	(ABC) transporter
AN935_17460	COG5002	protein histidine kinase activity
AN935_17465	COG0745	RESPONSE REGULATOR receiver
AN935_17475	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AN935_17480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_17485	COG1481	regulation of sporulation
AN935_17490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AN935_17495	COG1660	Displays ATPase and GTPase activities
AN935_17500	COG1051	belongs to the nudix hydrolase family
AN935_17505	COG0492	ferredoxin-NADP+ reductase activity
AN935_17510	COG3883	PFAM NLP P60 protein
AN935_17510	COG0791	NLP P60 protein
AN935_17515	COG0457	Tetratricopeptide repeat
AN935_17520	COG1132	(ABC) transporter
AN935_17540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AN935_17540	COG0140	phosphoribosyl-ATP diphosphatase activity
AN935_17545	COG0107	imidazoleglycerol-phosphate synthase activity
AN935_17550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AN935_17555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AN935_17560	COG0131	Imidazoleglycerol-phosphate dehydratase
AN935_17565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AN935_17570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AN935_17575	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AN935_17580	COG4990	cell redox homeostasis
AN935_17585	COG5297	Belongs to the glycosyl hydrolase family 6
AN935_17590	COG0110	maltose O-acetyltransferase activity
AN935_17595	COG0546	phosphoglycolate phosphatase activity
AN935_17600	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AN935_17605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AN935_17610	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AN935_17615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AN935_17620	COG0363	glucosamine-6-phosphate deaminase activity
AN935_17625	COG2188	Transcriptional regulator
AN935_17630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AN935_17635	COG1846	Transcriptional regulator
AN935_17640	COG2814	Major facilitator Superfamily
AN935_17645	COG1950	PFAM Membrane protein of
AN935_17650	COG1983	PspC domain protein
AN935_17655	COG3595	metallopeptidase activity
AN935_17670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN935_17675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AN935_17680	COG0556	nucleotide-excision repair
AN935_17685	COG4897	Protein conserved in bacteria
AN935_17695	COG0574	Belongs to the PEP-utilizing enzyme family
AN935_17695	COG3848	Pyruvate phosphate dikinase
AN935_17700	COG1309	transcriptional regulator
AN935_17705	COG2814	Major facilitator Superfamily
AN935_17710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN935_17720	COG3409	Peptidoglycan-binding domain 1 protein
AN935_17720	COG0793	Belongs to the peptidase S41A family
AN935_17725	COG2177	Part of the ABC transporter FtsEX involved in
AN935_17730	COG2884	Cell division ATP-binding protein ftsE
AN935_17735	COG2010	Cytochrome c
AN935_17740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_17745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AN935_17750	COG0653	protein targeting
AN935_17755	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AN935_17770	COG1516	flagellar protein fliS
AN935_17775	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AN935_17780	COG1334	flagellar protein FlaG
AN935_17785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN935_17790	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AN935_17795	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AN935_17805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN935_17810	COG1256	bacterial-type flagellum assembly
AN935_17810	COG4786	Flagellar basal body rod
AN935_17815	COG3418	PFAM FlgN family protein
AN935_17820	COG2747	anti-sigma28 factor FlgM
AN935_17830	COG1040	competence protein
AN935_17840	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AN935_17845	COG1307	EDD domain protein, DegV family
AN935_17850	COG2197	response regulator
AN935_17855	COG4585	Histidine kinase
AN935_17860	COG1739	Uncharacterized protein family UPF0029
AN935_17865	COG1316	TRANSCRIPTIONal
AN935_17870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN935_17875	COG0438	transferase activity, transferring glycosyl groups
AN935_17880	COG1215	transferase activity, transferring glycosyl groups
AN935_17885	COG3206	protein involved in exopolysaccharide biosynthesis
AN935_17890	COG3307	-O-antigen
AN935_17895	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AN935_17900	COG0438	transferase activity, transferring glycosyl groups
AN935_17900	COG0297	glycogen (starch) synthase activity
AN935_17905	COG2244	polysaccharide biosynthetic process
AN935_17920	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_17920	COG2247	cell wall binding repeat
AN935_17925	COG2385	sporulation resulting in formation of a cellular spore
AN935_17925	COG2247	cell wall binding repeat
AN935_17935	COG1316	TRANSCRIPTIONal
AN935_17940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AN935_17960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN935_17965	COG1134	teichoic acid transport
AN935_17970	COG1682	transport, permease protein
AN935_17975	COG1215	transferase activity, transferring glycosyl groups
AN935_17985	COG1181	Belongs to the D-alanine--D-alanine ligase family
AN935_17990	COG0463	Glycosyl transferase, family 2
AN935_17990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AN935_18000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AN935_18010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AN935_18045	COG4193	domain, Protein
AN935_18050	COG1482	cell wall glycoprotein biosynthetic process
AN935_18060	COG0697	spore germination
AN935_18065	COG0814	amino acid
AN935_18075	COG2814	Major facilitator Superfamily
AN935_18080	COG1316	TRANSCRIPTIONal
AN935_18085	COG0561	phosphatase activity
AN935_18090	COG0791	NLP P60 protein
AN935_18100	COG2843	Capsule synthesis protein
AN935_18110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AN935_18115	COG1609	Transcriptional regulator
AN935_18120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_18125	COG1869	D-ribose catabolic process
AN935_18130	COG1129	ABC transporter
AN935_18135	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN935_18140	COG1879	ABC-type sugar transport system periplasmic component
AN935_18145	COG3103	Sh3 type 3 domain protein
AN935_18155	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN935_18160	COG3527	Alpha-acetolactate decarboxylase
AN935_18165	COG0028	Belongs to the TPP enzyme family
AN935_18170	COG0583	DNA-binding transcription factor activity
AN935_18175	COG5337	Spore coat protein CotH
AN935_18185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN935_18195	COG0405	Gamma-glutamyltransferase
AN935_18200	COG1522	sequence-specific DNA binding
AN935_18205	COG2059	Chromate
AN935_18210	COG2059	Chromate
AN935_18220	COG0655	NAD(P)H dehydrogenase (quinone) activity
AN935_18225	COG0583	DNA-binding transcription factor activity
AN935_18240	COG5444	nuclease activity
AN935_18255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AN935_18260	COG4464	protein tyrosine phosphatase activity
AN935_18265	COG0489	protein tyrosine kinase activity
AN935_18270	COG3944	biosynthesis protein
AN935_18280	COG4715	Zinc finger, swim domain protein
AN935_18285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AN935_18290	COG0561	phosphatase activity
AN935_18295	COG1349	DNA-binding transcription factor activity
AN935_18300	COG0629	single-stranded DNA binding
AN935_18315	COG2602	Beta-lactamase
AN935_18320	COG3764	Sortase (surface protein transpeptidase)
AN935_18330	COG3279	Response regulator of the LytR AlgR family
AN935_18335	COG0745	RESPONSE REGULATOR receiver
AN935_18335	COG2972	Histidine kinase
AN935_18340	COG1970	mechanosensitive ion channel activity
AN935_18345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN935_18350	COG0457	Tetratricopeptide repeat
AN935_18355	COG4786	Flagellar basal body rod
AN935_18360	COG4786	Flagellar basal body rod
AN935_18365	COG1077	Cell shape determining protein MreB Mrl
AN935_18370	COG1609	Transcriptional regulator
AN935_18375	COG1846	Transcriptional regulator
AN935_18380	COG2814	Major facilitator Superfamily
AN935_18385	COG3420	alginic acid biosynthetic process
AN935_18390	COG1953	Uracil, thiamine, allantoin
AN935_18395	COG0477	Major facilitator Superfamily
AN935_18400	COG1335	isochorismatase
AN935_18410	COG0004	ammonium transporteR
AN935_18415	COG0347	Belongs to the P(II) protein family
AN935_18420	COG0671	phosphoesterase, PA-phosphatase related
AN935_18430	COG0739	heme binding
AN935_18435	COG1247	-acetyltransferase
AN935_18445	COG1086	Polysaccharide biosynthesis protein
AN935_18450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN935_18455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN935_18460	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AN935_18475	COG2089	acid synthase
AN935_18485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN935_18490	COG0789	Transcriptional regulator
AN935_18500	COG2910	NAD(P)H-binding
AN935_18505	COG1959	2 iron, 2 sulfur cluster binding
AN935_18510	COG0804	urea catabolic process
AN935_18515	COG0832	Belongs to the urease beta subunit family
AN935_18520	COG0831	urea catabolic process
AN935_18550	COG3237	CsbD-like
AN935_18555	COG1994	Peptidase M50
AN935_18560	COG0457	Tetratricopeptide repeat
AN935_18565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AN935_18570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AN935_18580	COG2304	oxidoreductase activity
AN935_18585	COG2304	oxidoreductase activity
AN935_18590	COG2385	sporulation resulting in formation of a cellular spore
AN935_18595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN935_18605	COG4836	Membrane
AN935_18625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AN935_18630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AN935_18635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AN935_18640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AN935_18645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AN935_18660	COG0356	it plays a direct role in the translocation of protons across the membrane
AN935_18670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AN935_18675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AN935_18680	COG4475	Protein of unknown function (DUF436)
AN935_18685	COG0698	ribose 5-phosphate isomerase
AN935_18690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN935_18695	COG1971	Probably functions as a manganese efflux pump
AN935_18700	COG0009	L-threonylcarbamoyladenylate synthase
AN935_18705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AN935_18725	COG2890	protein-(glutamine-N5) methyltransferase activity
AN935_18730	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AN935_18735	COG0346	lactoylglutathione lyase activity
AN935_18740	COG0789	Transcriptional regulator
AN935_18745	COG0679	Auxin Efflux Carrier
AN935_18750	COG0281	malic enzyme
AN935_18755	COG1435	thymidine kinase activity
AN935_18765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AN935_18775	COG1494	fructose-1,6-bisphosphatase
AN935_18780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN935_18785	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AN935_18790	COG0191	fructose-bisphosphate aldolase activity
AN935_18795	COG2204	response regulator
AN935_18800	COG4821	SIS domain
AN935_18805	COG0504	CTP synthase activity
AN935_18810	COG3343	RNA polymerase activity
AN935_18815	COG1960	acyl-CoA dehydrogenase activity
AN935_18820	COG2181	nitrate reductase activity
AN935_18820	COG0247	lactate metabolic process
AN935_18825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN935_18830	COG4294	response to UV
AN935_18840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AN935_18845	COG1132	(ABC) transporter
AN935_18850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN935_18860	COG2181	nitrate reductase activity
AN935_18865	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AN935_18870	COG1140	nitrate reductase beta subunit
AN935_18875	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AN935_18880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN935_18890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN935_18895	COG2223	nitrite transmembrane transporter activity
AN935_18900	COG0018	arginyl-trna synthetase
AN935_18905	COG4506	Protein conserved in bacteria
AN935_18915	COG0535	radical SAM domain protein
AN935_18925	COG1131	(ABC) transporter
AN935_18935	COG0612	Peptidase, M16
AN935_18950	COG3391	amine dehydrogenase activity
AN935_18955	COG3391	amine dehydrogenase activity
AN935_18965	COG0457	Tetratricopeptide repeat
AN935_18980	COG0010	Belongs to the arginase family
AN935_18985	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AN935_18990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN935_19000	COG1994	Peptidase M50
AN935_19005	COG1942	4-Oxalocrotonate Tautomerase
AN935_19010	COG1846	Transcriptional regulator
AN935_19015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN935_19030	COG1959	2 iron, 2 sulfur cluster binding
AN935_19035	COG3465	dGTPase activity
AN935_19040	COG1078	dGTPase activity
AN935_19045	COG4844	belongs to the
AN935_19055	COG0697	spore germination
AN935_19065	COG0095	Lipoate-protein ligase
AN935_19070	COG0583	DNA-binding transcription factor activity
AN935_19075	COG0280	phosphate acetyltransferase
AN935_19080	COG3253	May function as heme-dependent peroxidase
AN935_19085	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_19090	COG0436	Aminotransferase
AN935_19095	COG2814	Major facilitator Superfamily
AN935_19100	COG0151	Belongs to the GarS family
AN935_19105	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_19110	COG1917	Cupin 2, conserved barrel domain protein
AN935_19115	COG0077	Prephenate dehydratase
AN935_19120	COG2814	Major facilitator Superfamily
AN935_19125	COG0833	amino acid
AN935_19130	COG4187	Peptidase family M20/M25/M40
AN935_19135	COG1012	belongs to the aldehyde dehydrogenase family
AN935_19140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN935_19150	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AN935_19155	COG1091	dTDP-4-dehydrorhamnose reductase activity
AN935_19160	COG1088	dTDP-glucose 4,6-dehydratase activity
AN935_19165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AN935_19170	COG0456	acetyltransferase
AN935_19175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN935_19175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN935_19180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AN935_19185	COG0463	Glycosyl transferase, family 2
AN935_19200	COG2363	Small membrane protein
AN935_19205	COG2233	PERMEase
AN935_19215	COG1012	belongs to the aldehyde dehydrogenase family
AN935_19220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AN935_19225	COG1216	Glycosyl transferase, family 2
AN935_19230	COG0351	phosphomethylpyrimidine kinase
AN935_19240	COG1621	beta-fructofuranosidase activity
AN935_19245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_19245	COG1263	PTS System
AN935_19250	COG2116	formate transmembrane transporter activity
AN935_19255	COG3711	transcriptional antiterminator
AN935_19265	COG1404	Belongs to the peptidase S8 family
AN935_19270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_19275	COG0778	Nitroreductase
AN935_19280	COG0772	Belongs to the SEDS family
AN935_19305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AN935_19310	COG2261	transglycosylase associated protein
AN935_19315	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AN935_19320	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AN935_19325	COG2246	polysaccharide biosynthetic process
AN935_19330	COG1309	transcriptional regulator
AN935_19340	COG3162	membrane
AN935_19345	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_19350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AN935_19355	COG2837	iron assimilation
AN935_19360	COG2822	iron ion transport
AN935_19365	COG0672	)-iron permease
AN935_19370	COG0352	thiamine-phosphate diphosphorylase activity
AN935_19375	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AN935_19380	COG0583	DNA-binding transcription factor activity
AN935_19385	COG1380	Effector of murein hydrolase LrgA
AN935_19390	COG1346	cytolysis
AN935_19400	COG4895	conserved protein (DUF2196)
AN935_19405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AN935_19410	COG0346	lactoylglutathione lyase activity
AN935_19420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN935_19425	COG1404	Belongs to the peptidase S8 family
AN935_19430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_19430	COG1263	PTS System
AN935_19435	COG3711	transcriptional antiterminator
AN935_19440	COG1442	glycosyl transferase family 8
AN935_19445	COG5522	Integral membrane protein (intg_mem_TP0381)
AN935_19450	COG1846	Transcriptional regulator
AN935_19460	COG2234	aminopeptidase activity
AN935_19475	COG2814	Major facilitator Superfamily
AN935_19480	COG2357	RelA SpoT domain protein
AN935_19485	COG1575	Belongs to the MenA family. Type 1 subfamily
AN935_19500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_19505	COG1696	Membrane protein involved in D-alanine export
AN935_19510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN935_19515	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AN935_19520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AN935_19525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN935_19530	COG1486	melibiose metabolic process
AN935_19535	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN935_19540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN935_19545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN935_19550	COG3711	transcriptional antiterminator
AN935_19550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_19560	COG2094	Belongs to the DNA glycosylase MPG family
AN935_19565	COG0753	catalase activity
AN935_19570	COG2814	Major facilitator Superfamily
AN935_19575	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AN935_19580	COG1131	(ABC) transporter
AN935_19600	COG1595	DNA-templated transcription, initiation
AN935_19605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AN935_19610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AN935_19615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AN935_19620	COG4988	ABC transporter
AN935_19625	COG1294	oxidase, subunit
AN935_19630	COG1271	oxidase subunit
AN935_19635	COG3493	citrate carrier protein
AN935_19645	COG0726	polysaccharide deacetylase
AN935_19655	COG3842	ATPase activity
AN935_19660	COG2508	Transcriptional regulator
AN935_19665	COG1012	belongs to the aldehyde dehydrogenase family
AN935_19670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_19680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN935_19690	COG4585	Histidine kinase
AN935_19695	COG2197	response regulator
AN935_19700	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN935_19715	COG4894	glucomannan catabolic process
AN935_19725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN935_19730	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_19735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN935_19740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN935_19745	COG2610	gluconate transmembrane transporter activity
AN935_19755	COG0500	methyltransferase
AN935_19760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN935_19775	COG0693	protein deglycase activity
AN935_19775	COG0753	catalase activity
AN935_19780	COG2851	Citrate transporter
AN935_19785	COG2273	Hydrolase Family 16
AN935_19795	COG2723	6-phospho-beta-galactosidase activity
AN935_19800	COG1263	PTS System
AN935_19800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_19800	COG2190	(PTS) system
AN935_19805	COG3711	transcriptional antiterminator
AN935_19815	COG2270	Major facilitator Superfamily
AN935_19820	COG0513	Belongs to the DEAD box helicase family
AN935_19825	COG2755	lipolytic protein G-D-S-L family
AN935_19825	COG3401	FG-GAP repeat protein
AN935_19910	COG0697	spore germination
AN935_19920	COG0861	Integral membrane protein TerC family
AN935_19925	COG0589	response to stress
AN935_19930	COG2723	6-phospho-beta-galactosidase activity
AN935_19935	COG2190	(PTS) system
AN935_19935	COG1263	PTS System
AN935_19935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_19975	COG5444	nuclease activity
AN935_20010	COG3507	Belongs to the glycosyl hydrolase 43 family
AN935_20025	COG2986	histidine ammonia-lyase
AN935_20030	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AN935_20035	COG1228	amidohydrolase
AN935_20040	COG0010	Belongs to the arginase family
AN935_20045	COG0833	amino acid
AN935_20050	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AN935_20055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN935_20060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AN935_20065	COG2390	Transcriptional regulator
AN935_20075	COG3192	ethanolamine utilization protein
AN935_20080	COG2079	MmgE PrpD family protein
AN935_20085	COG1473	amidohydrolase
AN935_20090	COG1126	abc transporter atp-binding protein
AN935_20095	COG0765	amino acid transport
AN935_20100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_20105	COG0456	acetyltransferase
AN935_20110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_20115	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AN935_20120	COG0561	phosphatase activity
AN935_20150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_20155	COG5294	Protein conserved in bacteria
AN935_20160	COG0577	efflux transmembrane transporter activity
AN935_20165	COG1136	(ABC) transporter
AN935_20170	COG2205	protein histidine kinase activity
AN935_20175	COG0745	RESPONSE REGULATOR receiver
AN935_20180	COG0191	fructose-bisphosphate aldolase activity
AN935_20185	COG1082	Xylose isomerase domain protein TIM barrel
AN935_20190	COG1082	Xylose isomerase domain protein TIM barrel
AN935_20195	COG0673	inositol 2-dehydrogenase activity
AN935_20200	COG2814	Major facilitator Superfamily
AN935_20205	COG1082	Xylose isomerase domain protein TIM barrel
AN935_20210	COG3962	Belongs to the TPP enzyme family
AN935_20215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_20225	COG1012	belongs to the aldehyde dehydrogenase family
AN935_20230	COG1349	DNA-binding transcription factor activity
AN935_20235	COG0667	Aldo Keto reductase
AN935_20250	COG2271	Major facilitator Superfamily
AN935_20270	COG2814	Major facilitator Superfamily
AN935_20275	COG0326	Molecular chaperone. Has ATPase activity
AN935_20285	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_20290	COG1309	transcriptional regulator
AN935_20295	COG1012	belongs to the aldehyde dehydrogenase family
AN935_20305	COG0667	Aldo Keto reductase
AN935_20310	COG0789	Transcriptional regulator
AN935_20315	COG1714	RDD family
AN935_20320	COG2311	Membrane
AN935_20325	COG1917	Cupin 2, conserved barrel domain protein
AN935_20330	COG1309	transcriptional regulator
AN935_20335	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_20340	COG1846	Transcriptional regulator
AN935_20345	COG1380	Effector of murein hydrolase LrgA
AN935_20350	COG1346	cytolysis
AN935_20370	COG5039	Polysaccharide pyruvyl transferase
AN935_20375	COG1929	Belongs to the glycerate kinase type-1 family
AN935_20380	COG1802	Transcriptional regulator
AN935_20385	COG1070	Carbohydrate kinase
AN935_20390	COG2610	gluconate transmembrane transporter activity
AN935_20395	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AN935_20400	COG0450	alkyl hydroperoxide reductase
AN935_20405	COG3634	alkyl hydroperoxide reductase activity
AN935_20415	COG2723	6-phospho-beta-galactosidase activity
AN935_20420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_20420	COG1263	PTS System
AN935_20420	COG2190	(PTS) system
AN935_20425	COG2188	Transcriptional regulator
AN935_20430	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AN935_20445	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AN935_20455	COG1063	alcohol dehydrogenase
AN935_20475	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AN935_20485	COG0457	Tetratricopeptide repeat
AN935_20495	COG0010	Belongs to the arginase family
AN935_20500	COG0833	amino acid
AN935_20505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN935_20510	COG3829	transcription factor binding
AN935_20515	COG5002	protein histidine kinase activity
AN935_20520	COG0745	RESPONSE REGULATOR receiver
AN935_20540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN935_20545	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AN935_20550	COG4853	Protein conserved in bacteria
AN935_20555	COG4863	YycH protein
AN935_20560	COG5002	protein histidine kinase activity
AN935_20565	COG0745	RESPONSE REGULATOR receiver
AN935_20595	COG0346	lactoylglutathione lyase activity
AN935_20600	COG0305	Participates in initiation and elongation during chromosome replication
AN935_20620	COG3093	addiction module antidote protein HigA
AN935_20625	COG2807	transmembrane transport
AN935_20630	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AN935_20635	COG0359	binds to the 23S rRNA
AN935_20640	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AN935_20645	COG4241	membrane
AN935_20655	COG5577	PFAM Coat F domain
AN935_20660	COG1733	regulation of RNA biosynthetic process
AN935_20665	COG1227	inorganic diphosphatase activity
AN935_20680	COG2271	Major facilitator Superfamily
AN935_20690	COG4319	ketosteroid isomerase
AN935_20695	COG1357	PFAM Pentapeptide repeats (8 copies)
AN935_20700	COG2814	Major facilitator Superfamily
AN935_20705	COG0583	DNA-binding transcription factor activity
AN935_20710	COG2153	protein acetylation
AN935_20720	COG0583	DNA-binding transcription factor activity
AN935_20740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_20745	COG1733	regulation of RNA biosynthetic process
AN935_20750	COG1846	Transcriptional regulator
AN935_20755	COG2153	protein acetylation
AN935_20760	COG2364	Membrane
AN935_20775	COG2315	Protein conserved in bacteria
AN935_20785	COG0789	Transcriptional regulator
AN935_20805	COG2856	Zn peptidase
AN935_20815	COG1331	Highly conserved protein containing a thioredoxin domain
AN935_20820	COG1266	CAAX protease self-immunity
AN935_20825	COG0477	Major facilitator Superfamily
AN935_20825	COG2814	Major facilitator Superfamily
AN935_20830	COG0346	lactoylglutathione lyase activity
AN935_20835	COG1609	Transcriptional regulator
AN935_20840	COG0708	Exodeoxyribonuclease III
AN935_20845	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AN935_20850	COG0629	single-stranded DNA binding
AN935_20855	COG0360	Binds together with S18 to 16S ribosomal RNA
AN935_20860	COG0012	GTP binding
AN935_20865	COG0243	molybdopterin cofactor binding
AN935_20870	COG4481	Protein conserved in bacteria
AN935_20875	COG3949	Membrane
AN935_20885	COG1475	DNA binding
AN935_20890	COG1192	Involved in chromosome partitioning
AN935_20900	COG1475	DNA binding
AN935_20905	COG0357	Ribosomal RNA small subunit methyltransferase G
AN935_20910	COG0445	tRNA wobble uridine modification
AN935_20915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AN935_20920	COG1847	R3H domain protein
AN935_20925	COG0706	membrane insertase activity
AN935_20930	COG0594	ribonuclease P activity
AN935_20940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AN935_20945	COG0592	DNA-directed DNA polymerase activity
AN935_20950	COG2501	S4 domain
AN935_20955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AN935_20965	COG0187	DNA topoisomerase II activity
AN935_20970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AN935_20985	COG2801	Transposase and inactivated derivatives
AN935_21110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_21170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity