locus-tag	class	description
CKF48_00005	COG1368	sulfuric ester hydrolase activity
CKF48_00015	COG2814	Major facilitator Superfamily
CKF48_00020	COG1309	transcriptional regulator
CKF48_00025	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CKF48_00040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CKF48_00045	COG3162	membrane
CKF48_00060	COG4846	Membrane protein involved in cytochrome C biogenesis
CKF48_00065	COG2201	protein-glutamate methylesterase activity
CKF48_00070	COG0785	Cytochrome C biogenesis protein
CKF48_00080	COG3763	UPF0154 protein
CKF48_00100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CKF48_00105	COG1388	LysM domain
CKF48_00110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CKF48_00140	COG0174	glutamine synthetase
CKF48_00145	COG0789	Transcriptional regulator
CKF48_00150	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CKF48_00160	COG2860	membrane
CKF48_00165	COG0464	growth
CKF48_00170	COG1923	regulation of RNA biosynthetic process
CKF48_00175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CKF48_00180	COG1077	Cell shape determining protein MreB Mrl
CKF48_00185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CKF48_00190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CKF48_00200	COG4550	Control of competence regulator ComK, YlbF/YmcA
CKF48_00205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKF48_00210	COG1013	pyruvate-flavodoxin oxidoreductase activity
CKF48_00215	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CKF48_00215	COG0674	pyruvate-flavodoxin oxidoreductase activity
CKF48_00225	COG2359	stage V sporulation protein S
CKF48_00230	COG1692	metallophosphoesterase
CKF48_00235	COG1418	mRNA catabolic process
CKF48_00240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CKF48_00245	COG1058	Belongs to the CinA family
CKF48_00245	COG1546	Belongs to the CinA family
CKF48_00250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CKF48_00255	COG1426	Protein conserved in bacteria
CKF48_00270	COG0300	oxidoreductase activity
CKF48_00275	COG0612	Peptidase, M16
CKF48_00280	COG0612	Peptidase, M16
CKF48_00305	COG2188	Transcriptional regulator
CKF48_00310	COG4980	gas vesicle protein
CKF48_00310	COG1674	ftsk spoiiie
CKF48_00320	COG0740	serine-type endopeptidase activity
CKF48_00325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CKF48_00335	COG0527	aspartate kinase activity
CKF48_00340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKF48_00345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CKF48_00350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKF48_00360	COG0612	Peptidase, M16
CKF48_00365	COG0726	polysaccharide deacetylase
CKF48_00370	COG1185	polyribonucleotide nucleotidyltransferase activity
CKF48_00380	COG0196	riboflavin kinase activity
CKF48_00385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CKF48_00395	COG1550	Protein conserved in bacteria
CKF48_00405	COG1358	cellular component organization or biogenesis
CKF48_00410	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CKF48_00420	COG0779	Required for maturation of 30S ribosomal subunits
CKF48_00425	COG2176	DNA-directed DNA polymerase activity
CKF48_00430	COG0442	prolyl-tRNA aminoacylation
CKF48_00435	COG0750	zinc metalloprotease
CKF48_00440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CKF48_00445	COG4589	Belongs to the CDS family
CKF48_00450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CKF48_00455	COG0233	cytoplasmic translational termination
CKF48_00460	COG0528	UMP kinase activity
CKF48_00465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CKF48_00485	COG1191	sigma factor activity
CKF48_00490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CKF48_00495	COG1776	CheC inhibitor of MCP methylation
CKF48_00500	COG0835	chemotaxis
CKF48_00505	COG0643	Histidine kinase
CKF48_00505	COG2198	Histidine kinase
CKF48_00510	COG2201	protein-glutamate methylesterase activity
CKF48_00515	COG0455	bacterial-type flagellum organization
CKF48_00520	COG1419	protein localization to endoplasmic reticulum
CKF48_00525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CKF48_00530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CKF48_00535	COG1684	flagellar biosynthetic protein fliR
CKF48_00540	COG1987	bacterial-type flagellum assembly
CKF48_00545	COG1338	Plays a role in the flagellum-specific transport system
CKF48_00550	COG3190	flagellar
CKF48_00555	COG2201	protein-glutamate methylesterase activity
CKF48_00560	COG1776	CheC inhibitor of MCP methylation
CKF48_00560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CKF48_00565	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CKF48_00570	COG1580	Controls the rotational direction of flagella during chemotaxis
CKF48_00575	COG1582	Flagellar protein (FlbD)
CKF48_00585	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CKF48_00600	COG2882	bacterial-type flagellum organization
CKF48_00605	COG1157	protein secretion by the type III secretion system
CKF48_00615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CKF48_00620	COG1766	The M ring may be actively involved in energy transduction
CKF48_00625	COG1677	Flagellar hook-basal body complex protein FliE
CKF48_00630	COG1558	bacterial-type flagellum-dependent cell motility
CKF48_00635	COG1815	bacterial-type flagellum-dependent cell motility
CKF48_00645	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CKF48_00650	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CKF48_00655	COG4974	Belongs to the 'phage' integrase family
CKF48_00660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CKF48_00670	COG0758	DNA mediated transformation
CKF48_00675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CKF48_00695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CKF48_00710	COG0335	large ribosomal subunit rRNA binding
CKF48_00715	COG0336	Belongs to the RNA methyltransferase TrmD family
CKF48_00720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CKF48_00730	COG1837	Belongs to the UPF0109 family
CKF48_00740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CKF48_00745	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CKF48_00750	COG0552	protein localization to endoplasmic reticulum
CKF48_00755	COG1196	nuclear chromosome segregation
CKF48_00760	COG0571	ribonuclease III activity
CKF48_00765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKF48_00770	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_00775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CKF48_00780	COG0416	fatty acid biosynthetic process
CKF48_00785	COG1349	DNA-binding transcription factor activity
CKF48_00790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CKF48_00795	COG1461	Dihydroxyacetone kinase
CKF48_00800	COG1302	Protein conserved in bacteria
CKF48_00805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CKF48_00815	COG1564	THIamine pyrophosphokinase
CKF48_00825	COG1162	GTPase activity
CKF48_00830	COG0515	serine threonine protein kinase
CKF48_00830	COG2815	serine threonine protein kinase
CKF48_00835	COG0631	protein serine/threonine phosphatase activity
CKF48_00840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CKF48_00845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKF48_00845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CKF48_00850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CKF48_00855	COG0242	peptide deformylase activity
CKF48_00860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CKF48_00865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CKF48_00875	COG0194	GDP metabolic process
CKF48_00880	COG2052	Domain of unknown function (DUF370)
CKF48_00885	COG1561	YicC-like family, N-terminal region
CKF48_00910	COG2197	response regulator
CKF48_00925	COG0167	dihydroorotate dehydrogenase activity
CKF48_00930	COG0543	2 iron, 2 sulfur cluster binding
CKF48_00935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CKF48_00945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CKF48_00950	COG0540	Belongs to the ATCase OTCase family
CKF48_00965	COG0564	pseudouridine synthase activity
CKF48_00970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CKF48_00980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CKF48_00985	COG3599	regulation of cell shape
CKF48_00990	COG2302	S4 RNA-binding domain
CKF48_00995	COG0762	integral membrane protein
CKF48_01000	COG1799	cell septum assembly
CKF48_01005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CKF48_01015	COG1873	PFAM PRC-barrel domain
CKF48_01020	COG1191	sigma factor activity
CKF48_01025	COG1191	sigma factor activity
CKF48_01035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CKF48_01040	COG0849	cell division
CKF48_01045	COG3856	small basic protein
CKF48_01050	COG3879	Bacterial protein of unknown function (DUF881)
CKF48_01055	COG3879	Bacterial protein of unknown function (DUF881)
CKF48_01060	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CKF48_01075	COG0772	Belongs to the SEDS family
CKF48_01085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKF48_01090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKF48_01095	COG0768	penicillin binding
CKF48_01105	COG4839	cell division protein FtsL
CKF48_01110	COG0275	rRNA processing
CKF48_01115	COG2001	Belongs to the MraZ family
CKF48_01120	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CKF48_01130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKF48_01145	COG0511	ligase activity, forming carbon-carbon bonds
CKF48_01150	COG0439	Biotin carboxylase
CKF48_01155	COG0454	-acetyltransferase
CKF48_01165	COG1024	Enoyl-CoA hydratase
CKF48_01170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CKF48_01175	COG1399	metal-binding, possibly nucleic acid-binding protein
CKF48_01190	COG3480	Lon protease (S16) C-terminal proteolytic domain
CKF48_01195	COG1752	Esterase of the alpha-beta hydrolase superfamily
CKF48_01200	COG3314	Sporulation integral membrane protein YlbJ
CKF48_01205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CKF48_01210	COG0742	ribosomal rna small subunit methyltransferase
CKF48_01225	COG4471	UPF0298 protein
CKF48_01230	COG3679	Belongs to the UPF0342 family
CKF48_01255	COG2340	Cysteine-rich secretory protein family
CKF48_01275	COG3336	cytochrome c oxidase
CKF48_01300	COG1612	heme a metabolic process
CKF48_01305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CKF48_01310	COG0772	Belongs to the SEDS family
CKF48_01315	COG4838	Belongs to the UPF0358 family
CKF48_01320	COG2066	Belongs to the glutaminase family
CKF48_01325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CKF48_01330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CKF48_01340	COG4896	Protein conserved in bacteria
CKF48_01370	COG0483	inositol monophosphate 1-phosphatase activity
CKF48_01380	COG4493	Belongs to the UPF0637 family
CKF48_01385	COG4476	Belongs to the UPF0223 family
CKF48_01390	COG1982	Orn Lys Arg decarboxylase major
CKF48_01415	COG0726	polysaccharide deacetylase
CKF48_01435	COG0022	dehydrogenase e1 component
CKF48_01455	COG0242	peptide deformylase activity
CKF48_01460	COG0561	phosphatase activity
CKF48_01470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CKF48_01475	COG0569	domain protein
CKF48_01480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_01485	COG0450	alkyl hydroperoxide reductase
CKF48_01490	COG1473	amidohydrolase
CKF48_01495	COG2171	N-acyltransferase activity
CKF48_01500	COG0583	DNA-binding transcription factor activity
CKF48_01505	COG0517	IMP dehydrogenase activity
CKF48_01515	COG4703	Protein of unknown function (DUF1797)
CKF48_01530	COG2200	EAL domain
CKF48_01535	COG1408	metallophosphoesterase
CKF48_01550	COG0784	Response regulator, receiver
CKF48_01550	COG0835	chemotaxis
CKF48_01560	COG0436	Aminotransferase
CKF48_01565	COG2084	Dehydrogenase
CKF48_01575	COG2391	methyltransferase activity
CKF48_01580	COG0425	Belongs to the sulfur carrier protein TusA family
CKF48_01590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKF48_01600	COG4873	Protein conserved in bacteria
CKF48_01615	COG3949	Membrane
CKF48_01620	COG0542	response to heat
CKF48_01630	COG1846	Transcriptional regulator
CKF48_01635	COG3852	Histidine kinase
CKF48_01640	COG2223	nitrite transmembrane transporter activity
CKF48_01655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKF48_01660	COG0640	Transcriptional regulator
CKF48_01665	COG5002	protein histidine kinase activity
CKF48_01670	COG0840	transmembrane signaling receptor activity
CKF48_01675	COG3594	Acyltransferase
CKF48_01730	COG1191	sigma factor activity
CKF48_01740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CKF48_01745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CKF48_01750	COG3773	Cell wall hydrolase
CKF48_01755	COG1595	DNA-templated transcription, initiation
CKF48_01760	COG1404	Belongs to the peptidase S8 family
CKF48_01760	COG4412	M6 family metalloprotease domain protein
CKF48_01780	COG1510	regulation of RNA biosynthetic process
CKF48_01785	COG4175	Glycine betaine
CKF48_01785	COG0517	IMP dehydrogenase activity
CKF48_01790	COG4176	ABC-type proline glycine betaine transport system permease component
CKF48_01795	COG2113	Glycine betaine
CKF48_01800	COG2268	Band 7 protein
CKF48_01805	COG1585	Membrane protein implicated in regulation of membrane protease activity
CKF48_01815	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_01820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKF48_01825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKF48_01835	COG1966	Carbon starvation protein
CKF48_01845	COG2197	response regulator
CKF48_01850	COG4585	Histidine kinase
CKF48_01855	COG0842	Transport permease protein
CKF48_01860	COG1131	(ABC) transporter
CKF48_01875	COG0004	ammonium transporteR
CKF48_01895	COG2155	Conserved Protein
CKF48_01915	COG2382	esterase
CKF48_01925	COG2153	protein acetylation
CKF48_01930	COG2323	membrane
CKF48_01940	COG0210	DNA helicase
CKF48_01960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_01995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CKF48_02000	COG0475	glutathione-regulated potassium exporter activity
CKF48_02000	COG0569	domain protein
CKF48_02005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CKF48_02010	COG0564	pseudouridine synthase activity
CKF48_02015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CKF48_02020	COG2357	RelA SpoT domain protein
CKF48_02030	COG4116	CYTH
CKF48_02035	COG0741	lytic transglycosylase activity
CKF48_02035	COG1196	nuclear chromosome segregation
CKF48_02035	COG0739	heme binding
CKF48_02040	COG2346	COG2346, Truncated hemoglobins
CKF48_02050	COG1164	Oligoendopeptidase f
CKF48_02060	COG4862	establishment of competence for transformation
CKF48_02065	COG1393	Belongs to the ArsC family
CKF48_02070	COG0456	acetyltransferase
CKF48_02085	COG4608	Belongs to the ABC transporter superfamily
CKF48_02090	COG0444	Belongs to the ABC transporter superfamily
CKF48_02095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_02100	COG0601	transmembrane transport
CKF48_02105	COG4166	transmembrane transport
CKF48_02110	COG0180	Tryptophanyl-tRNA synthetase
CKF48_02120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_02125	COG0601	transmembrane transport
CKF48_02135	COG4608	Belongs to the ABC transporter superfamily
CKF48_02140	COG0444	Belongs to the ABC transporter superfamily
CKF48_02145	COG5504	Zn-dependent protease
CKF48_02150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKF48_02155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_02170	COG1744	ABC transporter substrate-binding protein PnrA-like
CKF48_02180	COG2267	carboxylic ester hydrolase activity
CKF48_02200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CKF48_02225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CKF48_02230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CKF48_02235	COG1763	Mo-molybdopterin cofactor biosynthetic process
CKF48_02240	COG0303	'Molybdopterin
CKF48_02245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CKF48_02250	COG2151	metal-sulfur cluster biosynthetic enzyme
CKF48_02255	COG1073	alpha beta
CKF48_02260	COG0561	phosphatase activity
CKF48_02270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_02275	COG1307	EDD domain protein, DegV family
CKF48_02285	COG2996	Protein conserved in bacteria
CKF48_02290	COG1666	GTP binding
CKF48_02295	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_02305	COG0367	asparagine synthase
CKF48_02315	COG5001	Diguanylate cyclase
CKF48_02315	COG3300	MHYT domain
CKF48_02325	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_02330	COG2311	Membrane
CKF48_02335	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_02375	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CKF48_02380	COG0398	Pfam SNARE associated Golgi protein
CKF48_02385	COG1316	TRANSCRIPTIONal
CKF48_02390	COG4946	Tricorn protease homolog
CKF48_02390	COG0823	Involved in the tonB-independent uptake of proteins
CKF48_02390	COG1506	peptidase
CKF48_02400	COG4903	ComK protein
CKF48_02410	COG0501	Belongs to the peptidase M48B family
CKF48_02420	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CKF48_02425	COG1396	sequence-specific DNA binding
CKF48_02430	COG1846	Transcriptional regulator
CKF48_02435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CKF48_02440	COG2368	4-hydroxyphenylacetate
CKF48_02445	COG5553	Cysteine dioxygenase type I
CKF48_02450	COG1959	2 iron, 2 sulfur cluster binding
CKF48_02455	COG1122	ATPase activity
CKF48_02500	COG4509	Sortase family
CKF48_02520	COG5386	Cell surface protein
CKF48_02530	COG1024	Enoyl-CoA hydratase
CKF48_02535	COG2267	carboxylic ester hydrolase activity
CKF48_02540	COG0431	NADPH-dependent FMN reductase
CKF48_02565	COG1464	Belongs to the NlpA lipoprotein family
CKF48_02575	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_02580	COG0095	Lipoate-protein ligase
CKF48_02595	COG1309	transcriptional regulator
CKF48_02605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CKF48_02610	COG2329	Antibiotic biosynthesis monooxygenase
CKF48_02615	COG3069	C4-dicarboxylate transmembrane transporter activity
CKF48_02625	COG4473	ABC transporter
CKF48_02630	COG1131	(ABC) transporter
CKF48_02635	COG0537	adenosine 5'-monophosphoramidase activity
CKF48_02640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CKF48_02655	COG1846	Transcriptional regulator
CKF48_02680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKF48_02695	COG4717	serine-type aminopeptidase activity
CKF48_02700	COG0420	3'-5' exonuclease activity
CKF48_02705	COG2197	response regulator
CKF48_02710	COG4585	Histidine kinase
CKF48_02725	COG1131	(ABC) transporter
CKF48_02730	COG1668	transmembrane transport
CKF48_02745	COG1024	Enoyl-CoA hydratase
CKF48_02755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKF48_02760	COG0561	phosphatase activity
CKF48_02770	COG4399	Belongs to the UPF0754 family
CKF48_02780	COG0189	ligase activity
CKF48_02785	COG0189	ligase activity
CKF48_02790	COG0189	ligase activity
CKF48_02810	COG1937	Protein conserved in bacteria
CKF48_02830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKF48_02845	COG1301	dicarboxylic acid transport
CKF48_02850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKF48_02855	COG1253	flavin adenine dinucleotide binding
CKF48_02860	COG5002	protein histidine kinase activity
CKF48_02860	COG3850	Histidine kinase
CKF48_02865	COG0745	RESPONSE REGULATOR receiver
CKF48_02870	COG0640	Transcriptional regulator
CKF48_02880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_02885	COG2719	SpoVR family
CKF48_02900	COG2197	response regulator
CKF48_02905	COG4585	Histidine kinase
CKF48_02905	COG2203	Gaf domain
CKF48_02910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CKF48_02915	COG3153	acetyltransferase
CKF48_02915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKF48_02935	COG0564	pseudouridine synthase activity
CKF48_02940	COG2261	transglycosylase associated protein
CKF48_02945	COG0656	L-ascorbic acid biosynthetic process
CKF48_02950	COG3973	AAA domain
CKF48_02955	COG1392	Phosphate transport regulator
CKF48_02960	COG0306	phosphate transporter
CKF48_02965	COG2252	PERMEase
CKF48_02970	COG1823	symporter activity
CKF48_02975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKF48_02980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKF48_02985	COG1309	transcriptional regulator
CKF48_02995	COG0460	homoserine dehydrogenase
CKF48_03000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKF48_03010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_03015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKF48_03040	COG2766	serine protein kinase
CKF48_03045	COG0778	Nitroreductase
CKF48_03050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CKF48_03060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CKF48_03065	COG3382	B3 4 domain protein
CKF48_03070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_03075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_03080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKF48_03085	COG1120	ATPase activity
CKF48_03200	COG0735	belongs to the Fur family
CKF48_03205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CKF48_03215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKF48_03220	COG0070	glutamate synthase
CKF48_03220	COG0069	glutamate synthase activity
CKF48_03220	COG0067	glutamate synthase
CKF48_03225	COG4129	membrane
CKF48_03240	COG0747	negative chemotaxis
CKF48_03245	COG4608	Belongs to the ABC transporter superfamily
CKF48_03250	COG0444	Belongs to the ABC transporter superfamily
CKF48_03255	COG1132	(ABC) transporter
CKF48_03275	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_03285	COG1988	membrane-bound metal-dependent
CKF48_03315	COG1090	epimerase
CKF48_03330	COG1132	(ABC) transporter
CKF48_03335	COG1132	(ABC) transporter
CKF48_03345	COG2076	Multidrug Resistance protein
CKF48_03350	COG2076	Multidrug Resistance protein
CKF48_03355	COG1309	transcriptional regulator
CKF48_03375	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKF48_03385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CKF48_03390	COG2508	Transcriptional regulator
CKF48_03395	COG1473	amidohydrolase
CKF48_03415	COG1657	PFAM Prenyltransferase squalene oxidase
CKF48_03420	COG1473	amidohydrolase
CKF48_03435	COG0788	formyltetrahydrofolate deformylase activity
CKF48_03460	COG3708	Transcriptional regulator
CKF48_03460	COG2207	Transcriptional regulator
CKF48_03465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CKF48_03475	COG1136	(ABC) transporter
CKF48_03480	COG0577	efflux transmembrane transporter activity
CKF48_03510	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CKF48_03515	COG3844	kynureninase activity
CKF48_03530	COG0385	Bile acid
CKF48_03535	COG0277	FAD linked oxidase domain protein
CKF48_03540	COG2186	Transcriptional regulator
CKF48_03545	COG0386	Belongs to the glutathione peroxidase family
CKF48_03550	COG0506	proline dehydrogenase activity
CKF48_03555	COG1556	Lactate utilization protein
CKF48_03560	COG1139	Iron-sulfur cluster binding protein
CKF48_03565	COG0247	lactate metabolic process
CKF48_03585	COG0840	transmembrane signaling receptor activity
CKF48_03605	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKF48_03620	COG0438	transferase activity, transferring glycosyl groups
CKF48_03625	COG0438	transferase activity, transferring glycosyl groups
CKF48_03630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKF48_03635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CKF48_03640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CKF48_03645	COG5337	Spore coat protein CotH
CKF48_03655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKF48_03660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CKF48_03680	COG0535	radical SAM domain protein
CKF48_03690	COG0387	Pfam Sodium calcium exchanger
CKF48_03695	COG0477	Major facilitator Superfamily
CKF48_03705	COG1295	ribonuclease BN
CKF48_03715	COG4840	Belongs to the UPF0435 family
CKF48_03720	COG0024	Methionine aminopeptidase
CKF48_03725	COG0693	protein deglycase activity
CKF48_03740	COG2313	pseudouridylate synthase activity
CKF48_03750	COG1360	Flagellar Motor Protein
CKF48_03755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CKF48_03775	COG2309	aminopeptidase activity
CKF48_03790	COG1970	mechanosensitive ion channel activity
CKF48_03795	COG0670	Belongs to the BI1 family
CKF48_03810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CKF48_03815	COG0805	protein transport
CKF48_03825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKF48_03840	COG1607	acyl-coa hydrolase
CKF48_03845	COG0598	Magnesium transport protein CorA
CKF48_03855	COG1595	DNA-templated transcription, initiation
CKF48_03860	COG2244	polysaccharide biosynthetic process
CKF48_03865	COG0488	(ABC) transporter
CKF48_03870	COG2197	response regulator
CKF48_03910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKF48_03910	COG0723	plastoquinol--plastocyanin reductase activity
CKF48_03915	COG0513	Belongs to the DEAD box helicase family
CKF48_03920	COG2814	Major facilitator Superfamily
CKF48_03930	COG0604	alcohol dehydrogenase
CKF48_03935	COG0024	Methionine aminopeptidase
CKF48_03945	COG3275	phosphorelay sensor kinase activity
CKF48_03955	COG1966	Carbon starvation protein
CKF48_03960	COG2176	DNA-directed DNA polymerase activity
CKF48_03980	COG0579	oxidoreductase
CKF48_03990	COG0277	FAD linked oxidase domain protein
CKF48_03995	COG2186	Transcriptional regulator
CKF48_04015	COG1301	dicarboxylic acid transport
CKF48_04030	COG4565	transcriptional regulatory protein
CKF48_04035	COG3290	protein histidine kinase activity
CKF48_04040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKF48_04050	COG0427	acetyl-CoA hydrolase
CKF48_04055	COG3279	Response regulator of the LytR AlgR family
CKF48_04060	COG2233	PERMEase
CKF48_04065	COG1960	acyl-CoA dehydrogenase activity
CKF48_04070	COG2011	ABC-type metal ion transport system permease component
CKF48_04075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKF48_04095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKF48_04100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKF48_04120	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CKF48_04125	COG3850	Histidine kinase
CKF48_04125	COG5002	protein histidine kinase activity
CKF48_04130	COG0745	RESPONSE REGULATOR receiver
CKF48_04135	COG0667	Aldo Keto reductase
CKF48_04160	COG2002	toxin-antitoxin pair type II binding
CKF48_04185	COG2819	hydrolase of the alpha beta superfamily
CKF48_04190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_04195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_04205	COG5566	PFAM Mor transcription activator
CKF48_04210	COG0217	transcriptional regulatory protein
CKF48_04220	COG1846	Transcriptional regulator
CKF48_04235	COG0372	Belongs to the citrate synthase family
CKF48_04240	COG0583	DNA-binding transcription factor activity
CKF48_04245	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_04250	COG0840	transmembrane signaling receptor activity
CKF48_04255	COG0017	Asparaginyl-tRNA synthetase
CKF48_04275	COG1473	amidohydrolase
CKF48_04280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CKF48_04285	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_04290	COG3829	transcription factor binding
CKF48_04295	COG1132	(ABC) transporter
CKF48_04300	COG1132	(ABC) transporter
CKF48_04305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CKF48_04320	COG5002	protein histidine kinase activity
CKF48_04325	COG0745	RESPONSE REGULATOR receiver
CKF48_04330	COG1388	LysM domain
CKF48_04335	COG0456	acetyltransferase
CKF48_04345	COG1595	DNA-templated transcription, initiation
CKF48_04355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CKF48_04355	COG2755	lipolytic protein G-D-S-L family
CKF48_04375	COG4211	Belongs to the binding-protein-dependent transport system permease family
CKF48_04380	COG1129	ABC transporter
CKF48_04390	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CKF48_04395	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CKF48_04400	COG1850	ribulose-bisphosphate carboxylase activity
CKF48_04410	COG0235	Class ii aldolase
CKF48_04415	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CKF48_04425	COG0604	alcohol dehydrogenase
CKF48_04460	COG2318	DinB family
CKF48_04480	COG3011	Protein conserved in bacteria
CKF48_04505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKF48_04520	COG0586	Pfam SNARE associated Golgi protein
CKF48_04525	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CKF48_04530	COG1473	amidohydrolase
CKF48_04545	COG2814	Major facilitator Superfamily
CKF48_04555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CKF48_04570	COG3835	regulator
CKF48_04590	COG0529	Catalyzes the synthesis of activated sulfate
CKF48_04595	COG2046	Belongs to the sulfate adenylyltransferase family
CKF48_04600	COG0583	DNA-binding transcription factor activity
CKF48_04605	COG1063	alcohol dehydrogenase
CKF48_04610	COG0730	response to heat
CKF48_04635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKF48_04645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CKF48_04645	COG0165	Argininosuccinate lyase
CKF48_04670	COG0583	DNA-binding transcription factor activity
CKF48_04680	COG1072	(Pantothenic acid kinase))
CKF48_04690	COG1131	(ABC) transporter
CKF48_04705	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CKF48_04715	COG1764	response to oxidative stress
CKF48_04720	COG0477	Major facilitator Superfamily
CKF48_04730	COG0659	secondary active sulfate transmembrane transporter activity
CKF48_04745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_04750	COG0346	lactoylglutathione lyase activity
CKF48_04760	COG1597	lipid kinase activity
CKF48_04765	COG1335	isochorismatase
CKF48_04770	COG2814	Major facilitator Superfamily
CKF48_04775	COG1011	Hydrolase
CKF48_04785	COG0492	ferredoxin-NADP+ reductase activity
CKF48_04790	COG0737	Belongs to the 5'-nucleotidase family
CKF48_04795	COG4191	Histidine kinase
CKF48_04810	COG0500	methyltransferase
CKF48_04815	COG2226	methyltransferase
CKF48_04825	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_04835	COG0109	protoheme IX farnesyltransferase activity
CKF48_04860	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_04860	COG0604	alcohol dehydrogenase
CKF48_04860	COG3321	synthase
CKF48_04875	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CKF48_04880	COG2079	MmgE PrpD family protein
CKF48_04900	COG2814	Major facilitator Superfamily
CKF48_04915	COG1464	Belongs to the NlpA lipoprotein family
CKF48_04920	COG0436	Aminotransferase
CKF48_04925	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_04925	COG2202	Pas domain
CKF48_04945	COG0456	acetyltransferase
CKF48_04950	COG1309	transcriptional regulator
CKF48_04960	COG0789	Transcriptional regulator
CKF48_04965	COG1253	flavin adenine dinucleotide binding
CKF48_04975	COG0183	Belongs to the thiolase family
CKF48_04985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CKF48_04995	COG0596	Alpha beta hydrolase
CKF48_05010	COG0454	-acetyltransferase
CKF48_05020	COG4708	membrane
CKF48_05025	COG0861	Integral membrane protein TerC family
CKF48_05030	COG4187	Peptidase family M20/M25/M40
CKF48_05035	COG0527	aspartate kinase activity
CKF48_05045	COG4086	secreted protein
CKF48_05050	COG0739	heme binding
CKF48_05090	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_05095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_05100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKF48_05110	COG2234	aminopeptidase activity
CKF48_05115	COG0492	ferredoxin-NADP+ reductase activity
CKF48_05125	COG0166	Belongs to the GPI family
CKF48_05130	COG5002	protein histidine kinase activity
CKF48_05135	COG3853	Toxic anion resistance protein (TelA)
CKF48_05140	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CKF48_05145	COG5002	protein histidine kinase activity
CKF48_05150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKF48_05155	COG3764	Sortase (surface protein transpeptidase)
CKF48_05165	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_05170	COG1301	dicarboxylic acid transport
CKF48_05180	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_05190	COG0395	ABC-type sugar transport system, permease component
CKF48_05200	COG3842	ATPase activity
CKF48_05220	COG1609	Transcriptional regulator
CKF48_05235	COG2207	Transcriptional regulator
CKF48_05245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_05250	COG1116	anion transmembrane transporter activity
CKF48_05255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_05260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKF48_05265	COG0371	Dehydrogenase
CKF48_05270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKF48_05275	COG0730	response to heat
CKF48_05280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_05280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_05285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_05285	COG0425	Belongs to the sulfur carrier protein TusA family
CKF48_05290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_05295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_05300	COG2210	Belongs to the sulfur carrier protein TusA family
CKF48_05305	COG0425	Belongs to the sulfur carrier protein TusA family
CKF48_05310	COG1937	Protein conserved in bacteria
CKF48_05325	COG2207	Transcriptional regulator
CKF48_05325	COG3708	Transcriptional regulator
CKF48_05330	COG2818	Glycosylase
CKF48_05350	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_05380	COG0666	response to abiotic stimulus
CKF48_05400	COG1725	Transcriptional regulator
CKF48_05410	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_05425	COG0471	metal ion transport
CKF48_05430	COG0586	Pfam SNARE associated Golgi protein
CKF48_05435	COG0454	-acetyltransferase
CKF48_05450	COG1785	Belongs to the alkaline phosphatase family
CKF48_05470	COG1396	sequence-specific DNA binding
CKF48_05475	COG0124	histidyl-tRNA synthetase
CKF48_05490	COG0494	nUDIX hydrolase
CKF48_05510	COG5658	integral membrane protein
CKF48_05515	COG0471	metal ion transport
CKF48_05525	COG4948	Mandelate Racemase Muconate Lactonizing
CKF48_05535	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_05550	COG0154	amidase activity
CKF48_05560	COG0444	Belongs to the ABC transporter superfamily
CKF48_05565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_05575	COG0747	negative chemotaxis
CKF48_05600	COG2271	Major facilitator Superfamily
CKF48_05605	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_05610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKF48_05615	COG2186	Transcriptional regulator
CKF48_05620	COG2721	sulfolactate sulfo-lyase activity
CKF48_05625	COG1064	alcohol dehydrogenase
CKF48_05640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CKF48_05645	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CKF48_05670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CKF48_05685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_05715	COG3181	Tripartite tricarboxylate transporter family receptor
CKF48_05720	COG4565	transcriptional regulatory protein
CKF48_05725	COG3290	protein histidine kinase activity
CKF48_05750	COG0583	DNA-binding transcription factor activity
CKF48_05755	COG0402	S-adenosylhomocysteine deaminase activity
CKF48_05760	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CKF48_05765	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CKF48_05770	COG2070	2-Nitropropane dioxygenase
CKF48_05785	COG1024	Enoyl-CoA hydratase
CKF48_05790	COG0183	Belongs to the thiolase family
CKF48_05795	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_05800	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_05805	COG1024	Enoyl-CoA hydratase
CKF48_05835	COG3396	Phenylacetate-CoA oxygenase
CKF48_05840	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CKF48_05845	COG1141	Ferredoxin
CKF48_05855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKF48_05865	COG1131	(ABC) transporter
CKF48_05875	COG0745	RESPONSE REGULATOR receiver
CKF48_05880	COG2205	protein histidine kinase activity
CKF48_05885	COG0861	Integral membrane protein TerC family
CKF48_05905	COG3173	Aminoglycoside phosphotransferase
CKF48_05920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CKF48_05980	COG0840	transmembrane signaling receptor activity
CKF48_05985	COG1705	Flagellar rod assembly protein muramidase FlgJ
CKF48_06035	COG1136	(ABC) transporter
CKF48_06050	COG4608	Belongs to the ABC transporter superfamily
CKF48_06060	COG0601	transmembrane transport
CKF48_06090	COG0454	-acetyltransferase
CKF48_06100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKF48_06120	COG1476	TRANSCRIPTIONal
CKF48_06125	COG3655	Transcriptional regulator
CKF48_06150	COG4608	Belongs to the ABC transporter superfamily
CKF48_06155	COG0444	Belongs to the ABC transporter superfamily
CKF48_06160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_06165	COG0601	transmembrane transport
CKF48_06205	COG2080	2 iron, 2 sulfur cluster binding
CKF48_06210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CKF48_06215	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CKF48_06220	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CKF48_06225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CKF48_06230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CKF48_06235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKF48_06240	COG2508	Transcriptional regulator
CKF48_06245	COG2233	PERMEase
CKF48_06250	COG3195	allantoin biosynthetic process
CKF48_06250	COG3648	Uricase
CKF48_06255	COG2072	flavoprotein involved in K transport
CKF48_06260	COG2351	hydroxyisourate hydrolase activity
CKF48_06285	COG2356	endonuclease I
CKF48_06290	COG2814	Major facilitator Superfamily
CKF48_06305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_06320	COG0405	Gamma-glutamyltransferase
CKF48_06325	COG0154	amidase activity
CKF48_06340	COG1193	negative regulation of DNA recombination
CKF48_06345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CKF48_06375	COG4807	Protein conserved in bacteria
CKF48_06420	COG0450	alkyl hydroperoxide reductase
CKF48_06430	COG0640	Transcriptional regulator
CKF48_06480	COG0497	DNA recombination
CKF48_06495	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CKF48_06515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKF48_06525	COG1597	lipid kinase activity
CKF48_06555	COG0747	negative chemotaxis
CKF48_06560	COG0402	S-adenosylhomocysteine deaminase activity
CKF48_06565	COG1953	Uracil, thiamine, allantoin
CKF48_06575	COG3279	Response regulator of the LytR AlgR family
CKF48_06580	COG2972	Histidine kinase
CKF48_06585	COG4608	Belongs to the ABC transporter superfamily
CKF48_06590	COG0444	Belongs to the ABC transporter superfamily
CKF48_06610	COG0402	S-adenosylhomocysteine deaminase activity
CKF48_06615	COG0402	S-adenosylhomocysteine deaminase activity
CKF48_06620	COG0772	Belongs to the SEDS family
CKF48_06645	COG2226	methyltransferase
CKF48_06655	COG1694	Mazg nucleotide pyrophosphohydrolase
CKF48_06670	COG0778	Nitroreductase
CKF48_06675	COG1733	regulation of RNA biosynthetic process
CKF48_06685	COG1522	sequence-specific DNA binding
CKF48_06690	COG1335	isochorismatase
CKF48_06720	COG1695	Transcriptional regulator
CKF48_06735	COG0577	efflux transmembrane transporter activity
CKF48_06740	COG1136	(ABC) transporter
CKF48_06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKF48_06765	COG0681	Belongs to the peptidase S26 family
CKF48_06770	COG3227	Zinc metalloprotease (Elastase)
CKF48_06780	COG3973	AAA domain
CKF48_06790	COG2211	Major facilitator Superfamily
CKF48_06870	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_06895	COG1595	DNA-templated transcription, initiation
CKF48_06900	COG3773	Cell wall hydrolase
CKF48_06905	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKF48_06930	COG1227	inorganic diphosphatase activity
CKF48_06940	COG1063	alcohol dehydrogenase
CKF48_06960	COG0583	DNA-binding transcription factor activity
CKF48_06975	COG2124	cytochrome p450
CKF48_06980	COG1346	cytolysis
CKF48_06985	COG1380	Effector of murein hydrolase LrgA
CKF48_07035	COG0006	proline dipeptidase activity
CKF48_07040	COG1396	sequence-specific DNA binding
CKF48_07045	COG3192	ethanolamine utilization protein
CKF48_07055	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CKF48_07060	COG0154	amidase activity
CKF48_07070	COG1215	transferase activity, transferring glycosyl groups
CKF48_07085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKF48_07105	COG3620	sequence-specific DNA binding
CKF48_07110	COG5506	Protein of unknown function (DUF1694)
CKF48_07120	COG2224	Isocitrate lyase
CKF48_07125	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_07130	COG2211	Major facilitator Superfamily
CKF48_07155	COG2226	methyltransferase
CKF48_07170	COG4851	CamS sex pheromone cAM373 precursor
CKF48_07175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CKF48_07180	COG0210	DNA helicase
CKF48_07185	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CKF48_07200	COG4496	protein, YerC YecD
CKF48_07205	COG1470	cell adhesion involved in biofilm formation
CKF48_07220	COG0151	Belongs to the GarS family
CKF48_07225	COG0138	bifunctional purine biosynthesis protein purh
CKF48_07230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CKF48_07240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CKF48_07255	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CKF48_07260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CKF48_07265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CKF48_07270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CKF48_07275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CKF48_07285	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CKF48_07310	COG2252	PERMEase
CKF48_07325	COG1305	Transglutaminase-like
CKF48_07330	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CKF48_07335	COG0714	Associated with various cellular activities
CKF48_07340	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CKF48_07350	COG2304	oxidoreductase activity
CKF48_07370	COG2304	oxidoreductase activity
CKF48_07415	COG5444	nuclease activity
CKF48_07440	COG1511	domain protein
CKF48_07445	COG1674	ftsk spoiiie
CKF48_07445	COG0433	COG0433 Predicted ATPase
CKF48_07450	COG4499	WXG100 protein secretion system (Wss), protein YukC
CKF48_07455	COG5417	Belongs to the EsaB family
CKF48_07460	COG4842	Belongs to the WXG100 family
CKF48_07495	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_07505	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CKF48_07510	COG1253	flavin adenine dinucleotide binding
CKF48_07515	COG1253	flavin adenine dinucleotide binding
CKF48_07525	COG2239	Acts as a magnesium transporter
CKF48_07530	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_07540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CKF48_07560	COG0110	maltose O-acetyltransferase activity
CKF48_07575	COG3384	dioxygenase
CKF48_07580	COG2508	Transcriptional regulator
CKF48_07590	COG2146	nitrite reductase [NAD(P)H] activity
CKF48_07605	COG0583	DNA-binding transcription factor activity
CKF48_07695	COG3378	Phage plasmid primase P4 family
CKF48_07725	COG0582	viral genome integration into host DNA
CKF48_07730	COG0459	protein refolding
CKF48_07740	COG1266	CAAX protease self-immunity
CKF48_07750	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CKF48_07755	COG0315	cyclic pyranopterin monophosphate synthase activity
CKF48_07760	COG0488	(ABC) transporter
CKF48_07770	COG0456	acetyltransferase
CKF48_07775	COG1214	PFAM Peptidase M22, glycoprotease
CKF48_07780	COG0802	atpase or kinase
CKF48_07865	COG3091	SprT-like family
CKF48_07875	COG2183	response to ionizing radiation
CKF48_07880	COG2208	phosphoserine phosphatase activity
CKF48_07885	COG1191	sigma factor activity
CKF48_07890	COG2172	sigma factor antagonist activity
CKF48_07895	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_07900	COG2208	phosphoserine phosphatase activity
CKF48_07905	COG2172	sigma factor antagonist activity
CKF48_07910	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_07915	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_07920	COG2337	Toxic component of a toxin-antitoxin (TA) module
CKF48_07925	COG0864	Transcriptional regulator
CKF48_07935	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CKF48_07940	COG0736	holo-[acyl-carrier-protein] synthase activity
CKF48_07945	COG0705	Rhomboid family
CKF48_07950	COG3428	Bacterial PH domain
CKF48_07955	COG3402	PFAM membrane-flanked domain
CKF48_07965	COG0513	Belongs to the DEAD box helicase family
CKF48_07975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CKF48_07980	COG1181	Belongs to the D-alanine--D-alanine ligase family
CKF48_08000	COG2096	Adenosyltransferase
CKF48_08015	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CKF48_08020	COG1492	cobalamin metabolic process
CKF48_08035	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CKF48_08040	COG1120	ATPase activity
CKF48_08045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_08050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKF48_08060	COG2239	Acts as a magnesium transporter
CKF48_08065	COG0772	Belongs to the SEDS family
CKF48_08070	COG0018	arginyl-trna synthetase
CKF48_08075	COG0730	response to heat
CKF48_08080	COG1238	metal cluster binding
CKF48_08085	COG0783	Belongs to the Dps family
CKF48_08100	COG3832	glyoxalase III activity
CKF48_08105	COG0640	Transcriptional regulator
CKF48_08125	COG4607	ABC-type enterochelin transport system periplasmic component
CKF48_08130	COG4604	ABC transporter, ATP-binding protein
CKF48_08135	COG4605	iron ion homeostasis
CKF48_08140	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_08150	COG4608	Belongs to the ABC transporter superfamily
CKF48_08155	COG0791	NLP P60 protein
CKF48_08160	COG4948	Mandelate Racemase Muconate Lactonizing
CKF48_08165	COG1619	proteins homologs of microcin C7 resistance protein MccF
CKF48_08170	COG4166	transmembrane transport
CKF48_08175	COG0444	Belongs to the ABC transporter superfamily
CKF48_08180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_08185	COG0601	transmembrane transport
CKF48_08190	COG2362	D-Aminopeptidase
CKF48_08215	COG0560	Phosphoserine phosphatase
CKF48_08220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKF48_08220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKF48_08225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKF48_08225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKF48_08235	COG2514	catechol 2,3-dioxygenase activity
CKF48_08240	COG1733	regulation of RNA biosynthetic process
CKF48_08245	COG2427	Protein of unknown function (DUF1641)
CKF48_08250	COG3383	formate dehydrogenase (NAD+) activity
CKF48_08255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_08260	COG1271	oxidase subunit
CKF48_08265	COG1294	oxidase, subunit
CKF48_08275	COG2076	Multidrug Resistance protein
CKF48_08280	COG1309	transcriptional regulator
CKF48_08285	COG4191	Histidine kinase
CKF48_08295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CKF48_08300	COG2706	6-phosphogluconolactonase activity
CKF48_08320	COG4555	ABC transporter
CKF48_08355	COG3942	CHAP domain
CKF48_08355	COG1705	Flagellar rod assembly protein muramidase FlgJ
CKF48_08395	COG1414	Transcriptional regulator
CKF48_08400	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_08415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKF48_08420	COG2814	Major facilitator Superfamily
CKF48_08445	COG1216	Glycosyl transferase, family 2
CKF48_08450	COG1086	Polysaccharide biosynthesis protein
CKF48_08460	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_08465	COG0463	Glycosyl transferase, family 2
CKF48_08470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CKF48_08480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CKF48_08485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CKF48_08490	COG0590	tRNA wobble adenosine to inosine editing
CKF48_08505	COG1266	CAAX protease self-immunity
CKF48_08510	COG4978	Transcriptional regulator
CKF48_08510	COG0789	Transcriptional regulator
CKF48_08515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CKF48_08520	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_08530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_08540	COG0753	catalase activity
CKF48_08540	COG0693	protein deglycase activity
CKF48_08560	COG1414	Transcriptional regulator
CKF48_08565	COG2271	Major facilitator Superfamily
CKF48_08575	COG2267	carboxylic ester hydrolase activity
CKF48_08585	COG0196	riboflavin kinase activity
CKF48_08595	COG1960	acyl-CoA dehydrogenase activity
CKF48_08615	COG1619	proteins homologs of microcin C7 resistance protein MccF
CKF48_08630	COG1368	sulfuric ester hydrolase activity
CKF48_08635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CKF48_08640	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKF48_08650	COG0492	ferredoxin-NADP+ reductase activity
CKF48_08665	COG3850	Histidine kinase
CKF48_08665	COG5002	protein histidine kinase activity
CKF48_08670	COG0745	RESPONSE REGULATOR receiver
CKF48_08690	COG1301	dicarboxylic acid transport
CKF48_08765	COG0785	Cytochrome C biogenesis protein
CKF48_08775	COG0500	methyltransferase
CKF48_08780	COG0561	phosphatase activity
CKF48_08795	COG2855	membrane
CKF48_08800	COG0583	DNA-binding transcription factor activity
CKF48_08805	COG2207	Transcriptional regulator
CKF48_08805	COG3708	Transcriptional regulator
CKF48_08810	COG3973	AAA domain
CKF48_08815	COG3973	AAA domain
CKF48_08835	COG3859	Proton-coupled thiamine transporter YuaJ
CKF48_08845	COG1595	DNA-templated transcription, initiation
CKF48_08860	COG0393	Putative heavy-metal-binding
CKF48_08885	COG1027	Aspartate ammonia-lyase
CKF48_08905	COG1960	acyl-CoA dehydrogenase activity
CKF48_08910	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_08925	COG0135	phosphoribosylanthranilate isomerase activity
CKF48_08970	COG2226	methyltransferase
CKF48_09025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKF48_09050	COG1053	succinate dehydrogenase
CKF48_09060	COG0583	DNA-binding transcription factor activity
CKF48_09115	COG1131	(ABC) transporter
CKF48_09120	COG2205	protein histidine kinase activity
CKF48_09125	COG0745	RESPONSE REGULATOR receiver
CKF48_09130	COG0656	L-ascorbic acid biosynthetic process
CKF48_09135	COG2814	Major facilitator Superfamily
CKF48_09140	COG1733	regulation of RNA biosynthetic process
CKF48_09145	COG3620	sequence-specific DNA binding
CKF48_09155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_09160	COG1279	arginine transmembrane transporter activity
CKF48_09165	COG0572	uridine kinase
CKF48_09180	COG1595	DNA-templated transcription, initiation
CKF48_09185	COG1476	TRANSCRIPTIONal
CKF48_09205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CKF48_09210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CKF48_09215	COG4856	YbbR-like protein
CKF48_09220	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CKF48_09225	COG5662	AntiSigma factor
CKF48_09230	COG1595	DNA-templated transcription, initiation
CKF48_09305	COG0726	polysaccharide deacetylase
CKF48_09310	COG2194	sulfuric ester hydrolase activity
CKF48_09320	COG0489	protein tyrosine kinase activity
CKF48_09325	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKF48_09335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKF48_09385	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_09405	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CKF48_09410	COG1131	(ABC) transporter
CKF48_09430	COG1595	DNA-templated transcription, initiation
CKF48_09435	COG0745	RESPONSE REGULATOR receiver
CKF48_09440	COG2205	protein histidine kinase activity
CKF48_09445	COG2814	Major facilitator Superfamily
CKF48_09450	COG1131	(ABC) transporter
CKF48_09510	COG4974	Belongs to the 'phage' integrase family
CKF48_09590	COG1136	(ABC) transporter
CKF48_09620	COG2003	Belongs to the UPF0758 family
CKF48_09625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CKF48_09785	COG5484	DNA packaging
CKF48_09805	COG3677	Transposase
CKF48_09880	COG1484	DNA-dependent DNA replication
CKF48_09890	COG3723	Recombinational DNA repair protein, rece pathway
CKF48_09895	COG5377	YqaJ viral recombinase family
CKF48_09910	COG3646	Phage regulatory protein
CKF48_09910	COG3645	SOS response
CKF48_09930	COG1396	sequence-specific DNA binding
CKF48_09945	COG0582	viral genome integration into host DNA
CKF48_09950	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CKF48_09955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CKF48_09965	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CKF48_09970	COG1122	ATPase activity
CKF48_09975	COG1122	ATPase activity
CKF48_09985	COG0203	ribosomal protein L17
CKF48_09990	COG0202	RNA polymerase activity
CKF48_10005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CKF48_10010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CKF48_10015	COG0024	Methionine aminopeptidase
CKF48_10020	COG0563	adenylate kinase activity
CKF48_10025	COG0201	protein transport
CKF48_10035	COG1841	ribosomal large subunit assembly
CKF48_10040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CKF48_10045	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CKF48_10050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CKF48_10065	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CKF48_10070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CKF48_10075	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CKF48_10085	COG0255	Belongs to the universal ribosomal protein uL29 family
CKF48_10090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CKF48_10095	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CKF48_10100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CKF48_10105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CKF48_10110	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CKF48_10120	COG0088	Forms part of the polypeptide exit tunnel
CKF48_10125	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CKF48_10130	COG0051	transcription antitermination factor activity, RNA binding
CKF48_10135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CKF48_10135	COG0646	methionine synthase
CKF48_10140	COG1410	methionine synthase
CKF48_10140	COG0646	methionine synthase
CKF48_10145	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKF48_10150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CKF48_10160	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CKF48_10165	COG1358	cellular component organization or biogenesis
CKF48_10170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CKF48_10175	COG0085	RNA polymerase activity
CKF48_10180	COG2813	Specifically methylates the guanine in position
CKF48_10190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CKF48_10195	COG0081	regulation of translation
CKF48_10205	COG0250	Participates in transcription elongation, termination and antitermination
CKF48_10210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CKF48_10225	COG3688	RNA-binding protein containing a PIN domain
CKF48_10230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKF48_10240	COG0215	cysteine-tRNA ligase activity
CKF48_10245	COG1045	serine acetyltransferase
CKF48_10250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKF48_10255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CKF48_10260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CKF48_10265	COG4956	integral membrane protein (PIN domain superfamily)
CKF48_10275	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CKF48_10280	COG0542	response to heat
CKF48_10285	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CKF48_10290	COG3880	PFAM UvrB UvrC protein
CKF48_10385	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CKF48_10390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CKF48_10395	COG1396	sequence-specific DNA binding
CKF48_10400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CKF48_10405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CKF48_10410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CKF48_10415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CKF48_10420	COG0512	Glutamine amidotransferase of anthranilate synthase
CKF48_10425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CKF48_10430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKF48_10435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKF48_10440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CKF48_10445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CKF48_10450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKF48_10460	COG0037	tRNA processing
CKF48_10465	COG0515	serine threonine protein kinase
CKF48_10470	COG2304	oxidoreductase activity
CKF48_10475	COG2208	phosphoserine phosphatase activity
CKF48_10490	COG1098	S1 RNA binding domain
CKF48_10495	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CKF48_10510	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CKF48_10515	COG3956	TIGRFAM MazG family protein
CKF48_10520	COG2244	polysaccharide biosynthetic process
CKF48_10525	COG2002	toxin-antitoxin pair type II binding
CKF48_10540	COG0193	aminoacyl-tRNA hydrolase activity
CKF48_10550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CKF48_10555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CKF48_10565	COG0251	oxidation-reduction process
CKF48_10570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CKF48_10585	COG4466	Protein conserved in bacteria
CKF48_10595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CKF48_10605	COG3583	domain protein
CKF48_10605	COG3584	3D domain protein
CKF48_10610	COG0084	hydrolase, TatD family'
CKF48_10625	COG2002	toxin-antitoxin pair type II binding
CKF48_10630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CKF48_10635	COG2827	Endonuclease containing a URI domain
CKF48_10640	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CKF48_10645	COG4467	Involved in initiation control of chromosome replication
CKF48_10650	COG1774	PSP1 C-terminal conserved region
CKF48_10655	COG0470	DNA polymerase III
CKF48_10660	COG1728	Protein conserved in bacteria
CKF48_10665	COG3870	Protein conserved in bacteria
CKF48_10670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CKF48_10675	COG1982	Orn Lys Arg decarboxylase major
CKF48_10710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CKF48_10720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CKF48_10730	COG0590	tRNA wobble adenosine to inosine editing
CKF48_10735	COG1335	isochorismatase
CKF48_10740	COG1388	LysM domain
CKF48_10740	COG3858	chitin binding
CKF48_10745	COG1428	Deoxynucleoside kinase
CKF48_10750	COG1428	Deoxynucleoside kinase
CKF48_10760	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CKF48_10770	COG0516	GMP reductase activity
CKF48_10770	COG0517	IMP dehydrogenase activity
CKF48_10805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CKF48_10810	COG0187	DNA topoisomerase II activity
CKF48_10825	COG2501	S4 domain
CKF48_10830	COG0592	DNA-directed DNA polymerase activity
CKF48_10840	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CKF48_10845	COG0594	ribonuclease P activity
CKF48_10850	COG0706	membrane insertase activity
CKF48_10855	COG1847	R3H domain protein
CKF48_10860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CKF48_10870	COG0357	Ribosomal RNA small subunit methyltransferase G
CKF48_10875	COG1475	DNA binding
CKF48_10880	COG1192	Involved in chromosome partitioning
CKF48_10885	COG1475	DNA binding
CKF48_10900	COG4481	Protein conserved in bacteria
CKF48_10905	COG0012	GTP binding
CKF48_10910	COG0360	Binds together with S18 to 16S ribosomal RNA
CKF48_10920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CKF48_10940	COG4241	membrane
CKF48_10945	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CKF48_10950	COG0359	binds to the 23S rRNA
CKF48_10955	COG0305	Participates in initiation and elongation during chromosome replication
CKF48_10960	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CKF48_10995	COG0739	heme binding
CKF48_10995	COG0741	lytic transglycosylase activity
CKF48_10995	COG1196	nuclear chromosome segregation
CKF48_11000	COG0745	RESPONSE REGULATOR receiver
CKF48_11005	COG5002	protein histidine kinase activity
CKF48_11015	COG4853	Protein conserved in bacteria
CKF48_11020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CKF48_11025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKF48_11050	COG1595	DNA-templated transcription, initiation
CKF48_11055	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CKF48_11065	COG5002	protein histidine kinase activity
CKF48_11070	COG0745	RESPONSE REGULATOR receiver
CKF48_11075	COG0666	response to abiotic stimulus
CKF48_11085	COG0778	Nitroreductase
CKF48_11090	COG4978	Transcriptional regulator
CKF48_11090	COG0789	Transcriptional regulator
CKF48_11110	COG0494	nUDIX hydrolase
CKF48_11120	COG5444	nuclease activity
CKF48_11155	COG1187	pseudouridine synthase activity
CKF48_11180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_11210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CKF48_11235	COG0745	RESPONSE REGULATOR receiver
CKF48_11240	COG1136	(ABC) transporter
CKF48_11245	COG0577	efflux transmembrane transporter activity
CKF48_11260	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_11265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKF48_11275	COG1464	Belongs to the NlpA lipoprotein family
CKF48_11290	COG1070	Carbohydrate kinase
CKF48_11310	COG1115	amino acid carrier protein
CKF48_11315	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_11315	COG2202	Pas domain
CKF48_11325	COG3835	regulator
CKF48_11330	COG1929	Belongs to the glycerate kinase type-1 family
CKF48_11340	COG0583	DNA-binding transcription factor activity
CKF48_11350	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CKF48_11355	COG1984	allophanate hydrolase subunit 2
CKF48_11360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CKF48_11365	COG1914	H( )-stimulated, divalent metal cation uptake system
CKF48_11370	COG4336	lyase activity
CKF48_11390	COG0745	RESPONSE REGULATOR receiver
CKF48_11400	COG1280	lysine exporter protein (LysE YggA)
CKF48_11420	COG0840	transmembrane signaling receptor activity
CKF48_11420	COG3290	protein histidine kinase activity
CKF48_11430	COG0765	amino acid transport
CKF48_11435	COG1126	abc transporter atp-binding protein
CKF48_11445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CKF48_11450	COG0778	Nitroreductase
CKF48_11455	COG4536	flavin adenine dinucleotide binding
CKF48_11460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_11465	COG0577	efflux transmembrane transporter activity
CKF48_11470	COG1136	(ABC) transporter
CKF48_11475	COG0642	Histidine kinase
CKF48_11480	COG0745	RESPONSE REGULATOR receiver
CKF48_11485	COG2329	Antibiotic biosynthesis monooxygenase
CKF48_11490	COG2188	Transcriptional regulator
CKF48_11515	COG3627	carbon phosphorus lyase activity
CKF48_11520	COG4107	phosphonate C-P lyase system protein PhnK
CKF48_11525	COG3454	Phosphonate metabolism
CKF48_11530	COG4778	phosphonate C-P lyase system protein PhnL
CKF48_11535	COG0613	PHP domain protein
CKF48_11545	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CKF48_11550	COG3639	organic phosphonate transmembrane transporter activity
CKF48_11555	COG3639	organic phosphonate transmembrane transporter activity
CKF48_11560	COG2814	Major facilitator Superfamily
CKF48_11565	COG0477	Major facilitator Superfamily
CKF48_11575	COG3104	oligopeptide transport
CKF48_11595	COG0492	ferredoxin-NADP+ reductase activity
CKF48_11600	COG0366	Alpha amylase catalytic
CKF48_11605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CKF48_11630	COG4555	ABC transporter
CKF48_11635	COG1132	(ABC) transporter
CKF48_11640	COG0789	Transcriptional regulator
CKF48_11645	COG2031	fatty acid transporter
CKF48_11660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CKF48_11665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CKF48_11670	COG0351	phosphomethylpyrimidine kinase
CKF48_11685	COG0746	molybdenum cofactor guanylyltransferase activity
CKF48_11690	COG0314	molybdopterin synthase activity
CKF48_11695	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CKF48_11700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CKF48_11725	COG0444	Belongs to the ABC transporter superfamily
CKF48_11730	COG4608	Belongs to the ABC transporter superfamily
CKF48_11735	COG0405	Gamma-glutamyltransferase
CKF48_11740	COG2059	Chromate
CKF48_11745	COG2059	Chromate
CKF48_11755	COG3852	Histidine kinase
CKF48_11780	COG1176	ABC-type spermidine putrescine transport system, permease component I
CKF48_11815	COG0577	efflux transmembrane transporter activity
CKF48_11820	COG0577	efflux transmembrane transporter activity
CKF48_11820	COG1136	(ABC) transporter
CKF48_11830	COG0475	glutathione-regulated potassium exporter activity
CKF48_11840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKF48_11855	COG0165	Argininosuccinate lyase
CKF48_11865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKF48_11885	COG2197	response regulator
CKF48_11895	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_11910	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_11920	COG0028	Belongs to the TPP enzyme family
CKF48_11925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_11935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CKF48_11940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKF48_11955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CKF48_11970	COG2363	Small membrane protein
CKF48_11980	COG3773	Cell wall hydrolase
CKF48_11990	COG0280	phosphate acetyltransferase
CKF48_12010	COG1078	dGTPase activity
CKF48_12015	COG3465	dGTPase activity
CKF48_12035	COG1994	Peptidase M50
CKF48_12045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKF48_12055	COG0010	Belongs to the arginase family
CKF48_12060	COG4506	Protein conserved in bacteria
CKF48_12065	COG0018	arginyl-trna synthetase
CKF48_12080	COG4294	response to UV
CKF48_12085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKF48_12090	COG0247	lactate metabolic process
CKF48_12090	COG2181	nitrate reductase activity
CKF48_12095	COG0183	Belongs to the thiolase family
CKF48_12100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_12105	COG1960	acyl-CoA dehydrogenase activity
CKF48_12110	COG1960	acyl-CoA dehydrogenase activity
CKF48_12120	COG1703	isobutyryl-CoA mutase activity
CKF48_12120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_12120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_12130	COG0504	CTP synthase activity
CKF48_12135	COG4821	SIS domain
CKF48_12140	COG2204	response regulator
CKF48_12145	COG0191	fructose-bisphosphate aldolase activity
CKF48_12150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CKF48_12155	COG1494	fructose-1,6-bisphosphatase
CKF48_12160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CKF48_12170	COG1435	thymidine kinase activity
CKF48_12180	COG0697	spore germination
CKF48_12185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CKF48_12205	COG0009	L-threonylcarbamoyladenylate synthase
CKF48_12215	COG1971	Probably functions as a manganese efflux pump
CKF48_12225	COG0840	transmembrane signaling receptor activity
CKF48_12230	COG0698	ribose 5-phosphate isomerase
CKF48_12235	COG4475	Protein of unknown function (DUF436)
CKF48_12245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CKF48_12250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CKF48_12255	COG1404	Belongs to the peptidase S8 family
CKF48_12270	COG0356	it plays a direct role in the translocation of protons across the membrane
CKF48_12275	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKF48_12280	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CKF48_12285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKF48_12290	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CKF48_12295	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CKF48_12300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CKF48_12305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CKF48_12310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKF48_12315	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKF48_12320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKF48_12325	COG0649	NAD binding
CKF48_12335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKF48_12340	COG0839	Belongs to the complex I subunit 6 family
CKF48_12345	COG0713	ATP synthesis coupled electron transport
CKF48_12350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CKF48_12360	COG1007	ATP synthesis coupled electron transport
CKF48_12365	COG4836	Membrane
CKF48_12380	COG2385	sporulation resulting in formation of a cellular spore
CKF48_12385	COG0739	heme binding
CKF48_12390	COG0791	NLP P60 protein
CKF48_12390	COG1388	LysM domain
CKF48_12395	COG1609	Transcriptional regulator
CKF48_12400	COG1077	Cell shape determining protein MreB Mrl
CKF48_12405	COG4786	Flagellar basal body rod
CKF48_12410	COG4786	Flagellar basal body rod
CKF48_12440	COG0629	single-stranded DNA binding
CKF48_12460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CKF48_12480	COG3739	integral membrane protein
CKF48_12530	COG2851	Citrate transporter
CKF48_12535	COG4565	transcriptional regulatory protein
CKF48_12540	COG4565	transcriptional regulatory protein
CKF48_12545	COG3290	protein histidine kinase activity
CKF48_12550	COG1959	2 iron, 2 sulfur cluster binding
CKF48_12555	COG2910	NAD(P)H-binding
CKF48_12560	COG0592	DNA-directed DNA polymerase activity
CKF48_12585	COG0791	NLP P60 protein
CKF48_12585	COG1388	LysM domain
CKF48_12625	COG0534	Mate efflux family protein
CKF48_12630	COG0768	penicillin binding
CKF48_12645	COG1929	Belongs to the glycerate kinase type-1 family
CKF48_12655	COG1335	isochorismatase
CKF48_12690	COG0640	Transcriptional regulator
CKF48_12695	COG0697	spore germination
CKF48_12715	COG2011	ABC-type metal ion transport system permease component
CKF48_12720	COG1464	Belongs to the NlpA lipoprotein family
CKF48_12730	COG0667	Aldo Keto reductase
CKF48_12735	COG1960	acyl-CoA dehydrogenase activity
CKF48_12740	COG1473	amidohydrolase
CKF48_12750	COG0747	negative chemotaxis
CKF48_12755	COG0601	transmembrane transport
CKF48_12765	COG0444	Belongs to the ABC transporter superfamily
CKF48_12770	COG4608	Belongs to the ABC transporter superfamily
CKF48_12775	COG4948	Mandelate Racemase Muconate Lactonizing
CKF48_12785	COG0488	(ABC) transporter
CKF48_12790	COG3279	Response regulator of the LytR AlgR family
CKF48_12820	COG2851	Citrate transporter
CKF48_12825	COG3829	transcription factor binding
CKF48_12825	COG3290	protein histidine kinase activity
CKF48_12845	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_12850	COG0583	DNA-binding transcription factor activity
CKF48_12855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKF48_12860	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_12885	COG2031	fatty acid transporter
CKF48_12890	COG4172	Belongs to the ABC transporter superfamily
CKF48_12900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_12930	COG4682	membrane
CKF48_12950	COG1695	Transcriptional regulator
CKF48_12955	COG1830	Aldolase
CKF48_12965	COG3775	system Galactitol-specific IIC component
CKF48_12970	COG1070	Carbohydrate kinase
CKF48_12975	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_12980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKF48_12990	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_12995	COG1278	Cold shock
CKF48_13000	COG1120	ATPase activity
CKF48_13005	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_13010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_13015	COG4607	ABC-type enterochelin transport system periplasmic component
CKF48_13025	COG1454	alcohol dehydrogenase
CKF48_13030	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_13035	COG0659	secondary active sulfate transmembrane transporter activity
CKF48_13040	COG1609	Transcriptional regulator
CKF48_13070	COG0386	Belongs to the glutathione peroxidase family
CKF48_13075	COG1846	Transcriptional regulator
CKF48_13095	COG1846	Transcriptional regulator
CKF48_13105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_13110	COG0406	alpha-ribazole phosphatase activity
CKF48_13130	COG1960	acyl-CoA dehydrogenase activity
CKF48_13140	COG1126	abc transporter atp-binding protein
CKF48_13145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_13150	COG0765	amino acid transport
CKF48_13155	COG0765	amino acid transport
CKF48_13160	COG1695	Transcriptional regulator
CKF48_13180	COG1473	amidohydrolase
CKF48_13195	COG2610	gluconate transmembrane transporter activity
CKF48_13200	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_13215	COG1742	UPF0060 membrane protein
CKF48_13230	COG0154	amidase activity
CKF48_13255	COG0778	Nitroreductase
CKF48_13260	COG1733	regulation of RNA biosynthetic process
CKF48_13270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKF48_13290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CKF48_13300	COG2843	Capsule synthesis protein
CKF48_13310	COG3562	capsule polysaccharide
CKF48_13315	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CKF48_13320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CKF48_13325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CKF48_13325	COG0517	IMP dehydrogenase activity
CKF48_13330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CKF48_13355	COG3562	capsule polysaccharide
CKF48_13360	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CKF48_13365	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CKF48_13375	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CKF48_13400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CKF48_13410	COG1682	transport, permease protein
CKF48_13420	COG1134	teichoic acid transport
CKF48_13430	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKF48_13435	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CKF48_13440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CKF48_13445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CKF48_13450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CKF48_13450	COG1215	transferase activity, transferring glycosyl groups
CKF48_13455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CKF48_13460	COG4193	domain, Protein
CKF48_13460	COG5263	repeat protein
CKF48_13470	COG0728	peptidoglycan biosynthetic process
CKF48_13480	COG0438	transferase activity, transferring glycosyl groups
CKF48_13485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKF48_13500	COG1739	Uncharacterized protein family UPF0029
CKF48_13505	COG4585	Histidine kinase
CKF48_13515	COG1307	EDD domain protein, DegV family
CKF48_13520	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CKF48_13525	COG1040	competence protein
CKF48_13535	COG2747	anti-sigma28 factor FlgM
CKF48_13545	COG1256	bacterial-type flagellum assembly
CKF48_13545	COG4786	Flagellar basal body rod
CKF48_13550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CKF48_13560	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CKF48_13575	COG1334	flagellar protein FlaG
CKF48_13580	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CKF48_13585	COG1516	flagellar protein fliS
CKF48_13620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CKF48_13630	COG1175	transmembrane transport
CKF48_13640	COG3842	ATPase activity
CKF48_13655	COG1405	negative regulation of cell septum assembly
CKF48_13655	COG3012	SEC-C Motif Domain Protein
CKF48_13660	COG0653	protein targeting
CKF48_13680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_13690	COG2884	Cell division ATP-binding protein ftsE
CKF48_13695	COG2177	Part of the ABC transporter FtsEX involved in
CKF48_13700	COG0739	heme binding
CKF48_13705	COG0793	Belongs to the peptidase S41A family
CKF48_13705	COG3409	Peptidoglycan-binding domain 1 protein
CKF48_13710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKF48_13715	COG0488	(ABC) transporter
CKF48_13720	COG1846	Transcriptional regulator
CKF48_13725	COG0346	lactoylglutathione lyase activity
CKF48_13730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CKF48_13735	COG0400	carboxylic ester hydrolase activity
CKF48_13745	COG0655	NAD(P)H dehydrogenase (quinone) activity
CKF48_13750	COG0628	permease
CKF48_13760	COG0556	nucleotide-excision repair
CKF48_13765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CKF48_13775	COG3595	metallopeptidase activity
CKF48_13780	COG1950	PFAM Membrane protein of
CKF48_13785	COG1309	transcriptional regulator
CKF48_13795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CKF48_13800	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CKF48_13810	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CKF48_13820	COG0110	maltose O-acetyltransferase activity
CKF48_13825	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CKF48_13830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CKF48_13835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CKF48_13840	COG0131	Imidazoleglycerol-phosphate dehydratase
CKF48_13845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CKF48_13850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CKF48_13855	COG0107	imidazoleglycerol-phosphate synthase activity
CKF48_13860	COG0140	phosphoribosyl-ATP diphosphatase activity
CKF48_13860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CKF48_13865	COG0457	Tetratricopeptide repeat
CKF48_13870	COG0492	ferredoxin-NADP+ reductase activity
CKF48_13880	COG1051	belongs to the nudix hydrolase family
CKF48_13885	COG1660	Displays ATPase and GTPase activities
CKF48_13890	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CKF48_13900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKF48_13910	COG0740	serine-type endopeptidase activity
CKF48_13945	COG1404	Belongs to the peptidase S8 family
CKF48_14005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CKF48_14010	COG1647	Serine aminopeptidase, S33
CKF48_14015	COG0557	exoribonuclease II activity
CKF48_14020	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CKF48_14035	COG0346	lactoylglutathione lyase activity
CKF48_14040	COG0640	Transcriptional regulator
CKF48_14045	COG0640	Transcriptional regulator
CKF48_14050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CKF48_14055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKF48_14070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CKF48_14075	COG2030	dehydratase
CKF48_14085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_14095	COG1960	acyl-CoA dehydrogenase activity
CKF48_14105	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_14115	COG0586	Pfam SNARE associated Golgi protein
CKF48_14120	COG2814	Major facilitator Superfamily
CKF48_14130	COG1733	regulation of RNA biosynthetic process
CKF48_14135	COG0693	protein deglycase activity
CKF48_14140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_14145	COG0765	amino acid transport
CKF48_14150	COG1126	abc transporter atp-binding protein
CKF48_14175	COG2816	NAD+ diphosphatase activity
CKF48_14185	COG4149	molybdate abc transporter
CKF48_14190	COG0725	ABC transporter, periplasmic molybdate-binding protein
CKF48_14195	COG3842	ATPase activity
CKF48_14200	COG1910	domain protein
CKF48_14220	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_14225	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_14230	COG3829	transcription factor binding
CKF48_14230	COG3290	protein histidine kinase activity
CKF48_14235	COG2610	gluconate transmembrane transporter activity
CKF48_14240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CKF48_14245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CKF48_14250	COG1309	transcriptional regulator
CKF48_14255	COG2409	Drug exporters of the RND superfamily
CKF48_14255	COG1033	growth of symbiont in host cell
CKF48_14260	COG2011	ABC-type metal ion transport system permease component
CKF48_14265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKF48_14270	COG1464	Belongs to the NlpA lipoprotein family
CKF48_14275	COG0371	Dehydrogenase
CKF48_14300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CKF48_14315	COG0668	transmembrane transport
CKF48_14320	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CKF48_14335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_14340	COG4597	amino acid ABC transporter
CKF48_14345	COG0765	amino acid transport
CKF48_14350	COG1126	abc transporter atp-binding protein
CKF48_14500	COG0772	Belongs to the SEDS family
CKF48_14525	COG5577	PFAM Coat F domain
CKF48_14535	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_14535	COG1024	Enoyl-CoA hydratase
CKF48_14540	COG0183	Belongs to the thiolase family
CKF48_14545	COG1960	acyl-CoA dehydrogenase activity
CKF48_14550	COG1393	Belongs to the ArsC family
CKF48_14555	COG0509	glycine decarboxylation via glycine cleavage system
CKF48_14560	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CKF48_14565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_14580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKF48_14585	COG2011	ABC-type metal ion transport system permease component
CKF48_14590	COG1464	Belongs to the NlpA lipoprotein family
CKF48_14595	COG0396	ATPase activity
CKF48_14600	COG0719	Fe-S assembly protein
CKF48_14605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CKF48_14610	COG0822	iron-sulfur transferase activity
CKF48_14615	COG0719	Fe-S assembly protein
CKF48_14620	COG3409	Peptidoglycan-binding domain 1 protein
CKF48_14620	COG5632	N-Acetylmuramoyl-L-alanine amidase
CKF48_14625	COG1309	transcriptional regulator
CKF48_14630	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_14635	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CKF48_14650	COG1801	Protein of unknown function DUF72
CKF48_14655	COG3377	Domain of unknown function (DUF1805)
CKF48_14660	COG1757	Na H antiporter
CKF48_14670	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKF48_14680	COG0411	ABC transporter
CKF48_14690	COG0739	heme binding
CKF48_14695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CKF48_14705	COG4470	Protein conserved in bacteria
CKF48_14720	COG2445	Protein of unknown function DUF86
CKF48_14725	COG0647	UMP catabolic process
CKF48_14730	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CKF48_14735	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CKF48_14745	COG1349	DNA-binding transcription factor activity
CKF48_14755	COG0460	homoserine dehydrogenase
CKF48_14760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CKF48_14765	COG0083	homoserine kinase activity
CKF48_14770	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CKF48_14775	COG4837	Protein of unknown function (DUF1462)
CKF48_14780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CKF48_14805	COG1252	NADH dehydrogenase
CKF48_14815	COG0316	Belongs to the HesB IscA family
CKF48_14825	COG1252	NADH dehydrogenase
CKF48_14835	COG1802	Transcriptional regulator
CKF48_14870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKF48_14890	COG3584	3D domain protein
CKF48_14895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKF48_14900	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CKF48_14905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CKF48_14910	COG2056	Na+-H+ antiporter family
CKF48_14915	COG0789	Transcriptional regulator
CKF48_14925	COG1115	amino acid carrier protein
CKF48_14930	COG2508	Transcriptional regulator
CKF48_14930	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CKF48_14935	COG0686	Belongs to the AlaDH PNT family
CKF48_14940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CKF48_14965	COG2050	protein possibly involved in aromatic compounds catabolism
CKF48_14970	COG1320	monovalent cation:proton antiporter activity
CKF48_14975	COG2212	antiporter activity
CKF48_14980	COG1863	multisubunit Na H antiporter MnhE subunit
CKF48_14985	COG0651	ATP synthesis coupled electron transport
CKF48_14990	COG1006	Multisubunit Na H antiporter MnhC subunit
CKF48_14995	COG2111	Na H antiporter
CKF48_15000	COG2111	Na H antiporter
CKF48_15000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CKF48_15010	COG5018	Exonuclease
CKF48_15020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CKF48_15030	COG2032	superoxide dismutase activity
CKF48_15040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CKF48_15050	COG2267	carboxylic ester hydrolase activity
CKF48_15060	COG1098	S1 RNA binding domain
CKF48_15065	COG1979	alcohol dehydrogenase
CKF48_15075	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CKF48_15110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CKF48_15115	COG0702	epimerase
CKF48_15120	COG2356	endonuclease I
CKF48_15150	COG3944	biosynthesis protein
CKF48_15155	COG0489	protein tyrosine kinase activity
CKF48_15160	COG1086	Polysaccharide biosynthesis protein
CKF48_15165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CKF48_15170	COG0438	transferase activity, transferring glycosyl groups
CKF48_15175	COG1442	glycosyl transferase family 8
CKF48_15175	COG1216	Glycosyl transferase, family 2
CKF48_15180	COG0438	transferase activity, transferring glycosyl groups
CKF48_15185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CKF48_15185	COG0463	Glycosyl transferase, family 2
CKF48_15195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CKF48_15200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CKF48_15210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CKF48_15215	COG1396	sequence-specific DNA binding
CKF48_15230	COG1216	Glycosyl transferase, family 2
CKF48_15265	COG1132	(ABC) transporter
CKF48_15285	COG0457	Tetratricopeptide repeat
CKF48_15285	COG0463	Glycosyl transferase, family 2
CKF48_15305	COG0706	membrane insertase activity
CKF48_15335	COG1733	regulation of RNA biosynthetic process
CKF48_15350	COG1959	2 iron, 2 sulfur cluster binding
CKF48_15355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CKF48_15375	COG1285	pathogenesis
CKF48_15515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CKF48_15520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CKF48_15525	COG0297	glycogen (starch) synthase activity
CKF48_15530	COG0058	SHG alpha-glucan phosphorylase activity
CKF48_15535	COG1834	amidinotransferase
CKF48_15540	COG1575	Belongs to the MenA family. Type 1 subfamily
CKF48_15545	COG1169	isochorismate synthase
CKF48_15550	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CKF48_15555	COG0596	Alpha beta hydrolase
CKF48_15560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CKF48_15565	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_15590	COG0803	Belongs to the bacterial solute-binding protein 9 family
CKF48_15590	COG3443	Belongs to the bacterial solute-binding protein 9 family
CKF48_15595	COG0288	reversible hydration of carbon dioxide
CKF48_15600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CKF48_15605	COG1854	S-ribosylhomocysteine lyase activity
CKF48_15615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKF48_15625	COG0783	Belongs to the Dps family
CKF48_15640	COG0494	nUDIX hydrolase
CKF48_15645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_15650	COG1116	anion transmembrane transporter activity
CKF48_15655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKF48_15660	COG1506	peptidase
CKF48_15675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CKF48_15680	COG0367	asparagine synthase
CKF48_15685	COG4990	cell redox homeostasis
CKF48_15690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CKF48_15695	COG2267	carboxylic ester hydrolase activity
CKF48_15705	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CKF48_15710	COG1242	4 iron, 4 sulfur cluster binding
CKF48_15725	COG2814	Major facilitator Superfamily
CKF48_15735	COG0495	leucyl-tRNA aminoacylation
CKF48_15740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_15760	COG1131	(ABC) transporter
CKF48_15790	COG2244	polysaccharide biosynthetic process
CKF48_15800	COG2851	Citrate transporter
CKF48_15805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKF48_15810	COG2186	Transcriptional regulator
CKF48_15825	COG1187	pseudouridine synthase activity
CKF48_15830	COG1349	DNA-binding transcription factor activity
CKF48_15835	COG1125	glycine betaine transport
CKF48_15835	COG0517	IMP dehydrogenase activity
CKF48_15840	COG1174	glycine betaine transport
CKF48_15845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKF48_15855	COG0628	permease
CKF48_15875	COG1289	transmembrane transporter activity
CKF48_15890	COG0477	Major facilitator Superfamily
CKF48_15900	COG2814	Major facilitator Superfamily
CKF48_15905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKF48_15920	COG1523	belongs to the glycosyl hydrolase 13 family
CKF48_15925	COG0510	thiamine kinase activity
CKF48_15935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CKF48_15940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_15950	COG1363	Peptidase, m42
CKF48_15955	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CKF48_15970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_15975	COG4848	Belongs to the UPF0354 family
CKF48_15980	COG1674	ftsk spoiiie
CKF48_15990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CKF48_16010	COG4980	gas vesicle protein
CKF48_16015	COG3118	belongs to the thioredoxin family
CKF48_16020	COG0849	cell division
CKF48_16025	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CKF48_16025	COG1605	Chorismate mutase
CKF48_16030	COG1609	Transcriptional regulator
CKF48_16035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CKF48_16050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CKF48_16050	COG0456	acetyltransferase
CKF48_16055	COG0583	DNA-binding transcription factor activity
CKF48_16060	COG2814	Major facilitator Superfamily
CKF48_16065	COG0583	DNA-binding transcription factor activity
CKF48_16070	COG0655	NAD(P)H dehydrogenase (quinone) activity
CKF48_16075	COG0662	Cupin 2, conserved barrel domain protein
CKF48_16095	COG0123	including yeast histone deacetylase and acetoin utilization protein
CKF48_16100	COG0517	IMP dehydrogenase activity
CKF48_16105	COG0454	-acetyltransferase
CKF48_16110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKF48_16130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CKF48_16150	COG1562	ergosterol biosynthetic process
CKF48_16185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_16195	COG1064	alcohol dehydrogenase
CKF48_16200	COG0789	Transcriptional regulator
CKF48_16210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CKF48_16215	COG2199	diguanylate cyclase activity
CKF48_16215	COG2203	Gaf domain
CKF48_16225	COG1956	GAF domain-containing protein
CKF48_16230	COG1309	transcriptional regulator
CKF48_16235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CKF48_16240	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CKF48_16245	COG1114	Component of the transport system for branched-chain amino acids
CKF48_16250	COG1104	cysteine desulfurase activity
CKF48_16255	COG0301	tRNA thio-modification
CKF48_16265	COG0583	DNA-binding transcription factor activity
CKF48_16270	COG0010	Belongs to the arginase family
CKF48_16275	COG0786	glutamate:sodium symporter activity
CKF48_16280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKF48_16285	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CKF48_16290	COG2962	Rard protein
CKF48_16295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CKF48_16305	COG1714	RDD family
CKF48_16315	COG3874	Sporulation protein YtfJ
CKF48_16320	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CKF48_16325	COG0827	DNA restriction-modification system
CKF48_16330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CKF48_16340	COG0521	Mo-molybdopterin cofactor biosynthetic process
CKF48_16350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CKF48_16355	COG0137	argininosuccinate synthase activity
CKF48_16360	COG0165	Argininosuccinate lyase
CKF48_16365	COG0589	response to stress
CKF48_16370	COG3924	membrane
CKF48_16375	COG4145	pantothenate transmembrane transporter activity
CKF48_16380	COG0471	metal ion transport
CKF48_16390	COG0006	proline dipeptidase activity
CKF48_16395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CKF48_16405	COG4109	DRTGG domain
CKF48_16415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CKF48_16430	COG0587	DNA-directed DNA polymerase activity
CKF48_16435	COG0281	malic enzyme
CKF48_16440	COG1725	Transcriptional regulator
CKF48_16445	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CKF48_16450	COG0825	malonyl-CoA metabolic process
CKF48_16455	COG0205	6-phosphofructokinase activity
CKF48_16465	COG0471	metal ion transport
CKF48_16470	COG3030	protein affecting phage T7 exclusion by the F plasmid
CKF48_16475	COG0628	permease
CKF48_16480	COG2707	UPF0756 membrane protein
CKF48_16485	COG0372	Belongs to the citrate synthase family
CKF48_16490	COG0538	isocitrate dehydrogenase activity
CKF48_16495	COG0039	L-malate dehydrogenase activity
CKF48_16510	COG5002	protein histidine kinase activity
CKF48_16515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKF48_16515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKF48_16520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CKF48_16525	COG1971	Probably functions as a manganese efflux pump
CKF48_16530	COG0237	dephospho-CoA kinase activity
CKF48_16535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CKF48_16540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CKF48_16545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CKF48_16555	COG1484	DNA-dependent DNA replication
CKF48_16565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CKF48_16570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CKF48_16580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CKF48_16585	COG3326	Membrane
CKF48_16590	COG0398	Pfam SNARE associated Golgi protein
CKF48_16600	COG0756	dUTP diphosphatase activity
CKF48_16605	COG1363	Peptidase, m42
CKF48_16615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKF48_16620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CKF48_16625	COG0072	phenylalanine-tRNA ligase activity
CKF48_16625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKF48_16635	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CKF48_16640	COG1286	toxin biosynthetic process
CKF48_16645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CKF48_16645	COG1796	DNA polymerase
CKF48_16655	COG3766	membrane
CKF48_16660	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_16665	COG1309	transcriptional regulator
CKF48_16670	COG1024	Enoyl-CoA hydratase
CKF48_16675	COG2086	electron transfer activity
CKF48_16680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CKF48_16685	COG3118	belongs to the thioredoxin family
CKF48_16690	COG0322	excinuclease ABC activity
CKF48_16700	COG1719	4-vinyl reductase, 4VR
CKF48_16705	COG2009	succinate dehydrogenase
CKF48_16710	COG1053	succinate dehydrogenase
CKF48_16715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CKF48_16720	COG0737	Belongs to the 5'-nucleotidase family
CKF48_16725	COG0824	Thioesterase
CKF48_16730	COG2197	response regulator
CKF48_16735	COG1846	Transcriptional regulator
CKF48_16745	COG0514	ATP-dependent DNA helicase (RecQ)
CKF48_16750	COG5401	PFAM Sporulation and spore germination
CKF48_16760	COG0622	Phosphoesterase
CKF48_16770	COG0028	Belongs to the TPP enzyme family
CKF48_16775	COG0440	acetolactate synthase activity
CKF48_16785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKF48_16790	COG0473	3-isopropylmalate dehydrogenase activity
CKF48_16795	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CKF48_16800	COG0066	3-isopropylmalate dehydratase activity
CKF48_16805	COG0457	Tetratricopeptide repeat
CKF48_16805	COG1477	protein flavinylation
CKF48_16810	COG0544	peptidyl-prolyl cis-trans isomerase activity
CKF48_16815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CKF48_16820	COG0470	DNA polymerase III
CKF48_16820	COG1067	ATP-dependent peptidase activity
CKF48_16825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CKF48_16830	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CKF48_16835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_16840	COG0765	amino acid transport
CKF48_16845	COG1126	abc transporter atp-binding protein
CKF48_16860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CKF48_16875	COG0113	porphobilinogen synthase activity
CKF48_16880	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKF48_16885	COG1388	LysM domain
CKF48_16885	COG1388	LysM domain
CKF48_16895	COG0525	valine-tRNA ligase activity
CKF48_16900	COG0285	dihydrofolate synthase activity
CKF48_16925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CKF48_16935	COG1459	type II secretion system
CKF48_16940	COG4968	Prepilin-type N-terminal cleavage methylation domain
CKF48_16945	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CKF48_16970	COG0424	maF-like protein
CKF48_16975	COG2003	Belongs to the UPF0758 family
CKF48_16980	COG1077	Cell shape determining protein MreB Mrl
CKF48_16985	COG1792	Involved in formation and maintenance of cell shape
CKF48_16990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CKF48_16995	COG0850	regulation of cytokinetic process
CKF48_17000	COG2894	cell division
CKF48_17005	COG0739	heme binding
CKF48_17010	COG1994	Peptidase M50
CKF48_17015	COG1530	ribonuclease E activity
CKF48_17020	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CKF48_17025	COG2868	ribosomal protein
CKF48_17030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CKF48_17035	COG3290	protein histidine kinase activity
CKF48_17040	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CKF48_17045	COG4492	Belongs to the UPF0735 family
CKF48_17050	COG0077	Prephenate dehydratase
CKF48_17055	COG1827	regulation of RNA biosynthetic process
CKF48_17060	COG1104	cysteine desulfurase activity
CKF48_17065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CKF48_17070	COG0157	Belongs to the NadC ModD family
CKF48_17075	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CKF48_17080	COG1388	LysM domain
CKF48_17100	COG0582	viral genome integration into host DNA
CKF48_17125	COG0651	ATP synthesis coupled electron transport
CKF48_17130	COG1863	multisubunit Na H antiporter MnhE subunit
CKF48_17135	COG2212	antiporter activity
CKF48_17140	COG1320	monovalent cation:proton antiporter activity
CKF48_17170	COG1862	Preprotein translocase
CKF48_17180	COG2323	membrane
CKF48_17185	COG2244	polysaccharide biosynthetic process
CKF48_17195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKF48_17195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKF48_17200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CKF48_17205	COG5416	Lipopolysaccharide assembly protein A domain
CKF48_17210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CKF48_17210	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CKF48_17215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CKF48_17220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKF48_17225	COG1490	D-aminoacyl-tRNA deacylase activity
CKF48_17230	COG4991	sh3 domain protein
CKF48_17230	COG3103	Sh3 type 3 domain protein
CKF48_17230	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKF48_17235	COG0124	histidyl-tRNA synthetase
CKF48_17240	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CKF48_17260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CKF48_17275	COG1725	Transcriptional regulator
CKF48_17280	COG1131	(ABC) transporter
CKF48_17285	COG1131	(ABC) transporter
CKF48_17290	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CKF48_17295	COG0726	polysaccharide deacetylase
CKF48_17300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CKF48_17305	COG2364	Membrane
CKF48_17310	COG1959	2 iron, 2 sulfur cluster binding
CKF48_17315	COG1104	cysteine desulfurase activity
CKF48_17320	COG0482	sulfurtransferase activity
CKF48_17330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CKF48_17350	COG0628	permease
CKF48_17360	COG4472	Bacterial protein of unknown function (DUF965)
CKF48_17370	COG3906	Belongs to the UPF0473 family
CKF48_17375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CKF48_17385	COG0572	uridine kinase
CKF48_17390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CKF48_17395	COG0768	penicillin binding
CKF48_17420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKF48_17425	COG0626	cystathionine gamma-synthase activity
CKF48_17440	COG2329	Antibiotic biosynthesis monooxygenase
CKF48_17450	COG0688	phosphatidylethanolamine metabolic process
CKF48_17460	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CKF48_17465	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CKF48_17475	COG1534	Rna-binding protein
CKF48_17480	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CKF48_17485	COG1713	HD superfamily hydrolase involved in NAD metabolism
CKF48_17490	COG0799	negative regulation of ribosome biogenesis
CKF48_17495	COG2226	methyltransferase
CKF48_17500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKF48_17505	COG1596	polysaccharide export
CKF48_17505	COG1555	photosystem II stabilization
CKF48_17510	COG2131	deaminase
CKF48_17515	COG2333	competence protein COMEC
CKF48_17515	COG0658	competence protein
CKF48_17525	COG1466	dna polymerase III delta subunit
CKF48_17530	COG0268	Binds directly to 16S ribosomal RNA
CKF48_17545	COG0481	GTPase activity
CKF48_17550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKF48_17555	COG1420	regulation of RNA biosynthetic process
CKF48_17560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CKF48_17565	COG0443	Heat shock 70 kDa protein
CKF48_17575	COG2264	protein methyltransferase activity
CKF48_17580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CKF48_17585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKF48_17595	COG3620	sequence-specific DNA binding
CKF48_17600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CKF48_17605	COG1283	sodium-dependent phosphate transmembrane transporter activity
CKF48_17610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CKF48_17615	COG1610	YqeY-like protein
CKF48_17620	COG1030	water channel activity
CKF48_17625	COG4864	UPF0365 protein
CKF48_17645	COG1702	phosphate starvation-inducible protein PhoH
CKF48_17650	COG1480	7TM receptor with intracellular HD hydrolase
CKF48_17660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CKF48_17665	COG0295	cytidine deaminase activity
CKF48_17670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CKF48_17680	COG1381	Involved in DNA repair and RecF pathway recombination
CKF48_17685	COG0752	glycyl-tRNA synthetase alpha subunit
CKF48_17690	COG0751	glycine-tRNA ligase activity
CKF48_17695	COG0517	IMP dehydrogenase activity
CKF48_17700	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CKF48_17705	COG1671	Belongs to the UPF0178 family
CKF48_17710	COG0358	DNA primase activity
CKF48_17715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CKF48_17720	COG1960	acyl-CoA dehydrogenase activity
CKF48_17725	COG2010	Cytochrome c
CKF48_17730	COG2384	SAM-dependent methyltransferase
CKF48_17735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CKF48_17750	COG0513	Belongs to the DEAD box helicase family
CKF48_17755	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CKF48_17765	COG1121	(ABC) transporter
CKF48_17770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKF48_17775	COG0735	belongs to the Fur family
CKF48_17780	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CKF48_17785	COG4709	membrane
CKF48_17790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CKF48_17800	COG5521	maltodextrose utilization protein MalA
CKF48_17805	COG1283	sodium-dependent phosphate transmembrane transporter activity
CKF48_17810	COG2839	Protein conserved in bacteria
CKF48_17815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CKF48_17820	COG0477	Major facilitator Superfamily
CKF48_17830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CKF48_17835	COG0573	inorganic phosphate transmembrane transporter activity
CKF48_17840	COG0581	inorganic phosphate transmembrane transporter activity
CKF48_17845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CKF48_17850	COG0704	Plays a role in the regulation of phosphate uptake
CKF48_17890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CKF48_17895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CKF48_17910	COG0457	Tetratricopeptide repeat
CKF48_17910	COG0705	Rhomboid family
CKF48_17915	COG0697	spore germination
CKF48_17920	COG4483	Protein conserved in bacteria
CKF48_17925	COG1940	carbohydrate kinase activity
CKF48_17940	COG0011	TIGRFAM Protein of
CKF48_17950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_17970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CKF48_17975	COG1459	type II secretion system
CKF48_17980	COG4537	Required for transformation and DNA binding
CKF48_17985	COG4970	Tfp pilus assembly protein FimT
CKF48_18015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CKF48_18020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CKF48_18035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_18040	COG0095	Lipoate-protein ligase
CKF48_18050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKF48_18055	COG1752	Esterase of the alpha-beta hydrolase superfamily
CKF48_18070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CKF48_18075	COG0006	proline dipeptidase activity
CKF48_18080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CKF48_18090	COG1785	Belongs to the alkaline phosphatase family
CKF48_18135	COG0511	ligase activity, forming carbon-carbon bonds
CKF48_18140	COG0439	Biotin carboxylase
CKF48_18145	COG1302	Protein conserved in bacteria
CKF48_18150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKF48_18155	COG1570	exodeoxyribonuclease VII activity
CKF48_18160	COG1722	exodeoxyribonuclease VII activity
CKF48_18170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CKF48_18175	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CKF48_18185	COG0497	DNA recombination
CKF48_18190	COG0750	zinc metalloprotease
CKF48_18195	COG0745	RESPONSE REGULATOR receiver
CKF48_18200	COG4974	Belongs to the 'phage' integrase family
CKF48_18230	COG0582	viral genome integration into host DNA
CKF48_18300	COG3290	protein histidine kinase activity
CKF48_18300	COG3829	transcription factor binding
CKF48_18305	COG0280	phosphate acetyltransferase
CKF48_18315	COG3426	butyrate kinase activity
CKF48_18320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKF48_18325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CKF48_18330	COG0022	dehydrogenase e1 component
CKF48_18335	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKF48_18340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_18345	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_18345	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_18350	COG1703	isobutyryl-CoA mutase activity
CKF48_18360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_18365	COG0765	amino acid transport
CKF48_18370	COG1126	abc transporter atp-binding protein
CKF48_18375	COG4129	membrane
CKF48_18380	COG1376	ErfK ybiS ycfS ynhG family protein
CKF48_18390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CKF48_18395	COG2195	Cleaves the N-terminal amino acid of tripeptides
CKF48_18405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CKF48_18410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CKF48_18415	COG1234	tRNA 3'-trailer cleavage
CKF48_18420	COG0733	neurotransmitter:sodium symporter activity
CKF48_18425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKF48_18430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_18435	COG0300	oxidoreductase activity
CKF48_18440	COG1902	pentaerythritol trinitrate reductase activity
CKF48_18445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CKF48_18455	COG0583	DNA-binding transcription factor activity
CKF48_18460	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_18495	COG1073	alpha beta
CKF48_18500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKF48_18515	COG0667	Aldo Keto reductase
CKF48_18530	COG1379	DNA repair
CKF48_18535	COG0697	spore germination
CKF48_18545	COG1300	Membrane
CKF48_18550	COG0735	belongs to the Fur family
CKF48_18560	COG4974	Belongs to the 'phage' integrase family
CKF48_18580	COG1686	Belongs to the peptidase S11 family
CKF48_18615	COG0697	spore germination
CKF48_18630	COG1547	Domain of unknown function (DUF309)
CKF48_18640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CKF48_18645	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CKF48_18660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CKF48_18665	COG1686	Belongs to the peptidase S11 family
CKF48_18670	COG2715	membrane protein required for spore maturation
CKF48_18675	COG0700	Nucleoside recognition
CKF48_18680	COG1187	pseudouridine synthase activity
CKF48_18690	COG1333	cytochrome c biogenesis protein
CKF48_18695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CKF48_18700	COG0745	RESPONSE REGULATOR receiver
CKF48_18705	COG5002	protein histidine kinase activity
CKF48_18710	COG1595	DNA-templated transcription, initiation
CKF48_18720	COG0739	heme binding
CKF48_18725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CKF48_18730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKF48_18735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CKF48_18740	COG1141	Ferredoxin
CKF48_18745	COG4955	Helix-turn-helix domain
CKF48_18755	COG1266	CAAX protease self-immunity
CKF48_18760	COG0791	NLP P60 protein
CKF48_18760	COG1388	LysM domain
CKF48_18770	COG1408	metallophosphoesterase
CKF48_18775	COG4862	establishment of competence for transformation
CKF48_18780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CKF48_18785	COG0492	ferredoxin-NADP+ reductase activity
CKF48_18790	COG0252	asparaginase activity
CKF48_18795	COG2339	peptidase activity
CKF48_18800	COG3773	Cell wall hydrolase
CKF48_18800	COG3409	Peptidoglycan-binding domain 1 protein
CKF48_18805	COG2959	enzyme of heme biosynthesis
CKF48_18820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CKF48_18825	COG0204	Acyl-transferase
CKF48_18830	COG0539	negative regulation of cytoplasmic translation
CKF48_18835	COG1304	FMN binding
CKF48_18860	COG1160	GTP binding
CKF48_18865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CKF48_18880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CKF48_18885	COG0776	regulation of translation
CKF48_18890	COG0302	gtp cyclohydrolase
CKF48_18900	COG0142	geranyltranstransferase activity
CKF48_18905	COG2226	methyltransferase
CKF48_18910	COG0142	geranyltranstransferase activity
CKF48_18915	COG0105	UTP biosynthetic process
CKF48_18920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CKF48_18930	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CKF48_18935	COG4401	Chorismate mutase type I
CKF48_18940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKF48_18945	COG0287	Prephenate dehydrogenase
CKF48_18950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CKF48_18960	COG0457	Tetratricopeptide repeat
CKF48_18965	COG5582	Belongs to the UPF0302 family
CKF48_18980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CKF48_18990	COG4347	Protein of unknown function (DUF1405)
CKF48_19010	COG2738	Putative neutral zinc metallopeptidase
CKF48_19015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_19020	COG1694	Mazg nucleotide pyrophosphohydrolase
CKF48_19025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CKF48_19030	COG1803	Methylglyoxal synthase
CKF48_19035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CKF48_19040	COG0438	transferase activity, transferring glycosyl groups
CKF48_19045	COG0617	tRNA 3'-terminal CCA addition
CKF48_19060	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CKF48_19065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CKF48_19070	COG2304	oxidoreductase activity
CKF48_19075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CKF48_19075	COG1199	ATP-dependent helicase activity
CKF48_19090	COG0436	Aminotransferase
CKF48_19095	COG0017	Asparaginyl-tRNA synthetase
CKF48_19100	COG3935	DnaD domain protein
CKF48_19105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CKF48_19115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKF48_19115	COG4499	WXG100 protein secretion system (Wss), protein YukC
CKF48_19120	COG3331	DNA recombination
CKF48_19145	COG0601	transmembrane transport
CKF48_19150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_19155	COG0071	Belongs to the small heat shock protein (HSP20) family
CKF48_19160	COG1111	helicase
CKF48_19160	COG1205	dead DEAH box helicase
CKF48_19165	COG3359	exonuclease
CKF48_19180	COG4474	Belongs to the UPF0398 family
CKF48_19195	COG0116	Belongs to the methyltransferase superfamily
CKF48_19200	COG1199	ATP-dependent helicase activity
CKF48_19205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CKF48_19210	COG0697	spore germination
CKF48_19215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CKF48_19220	COG2233	PERMEase
CKF48_19230	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKF48_19240	COG2427	Protein of unknown function (DUF1641)
CKF48_19245	COG3383	formate dehydrogenase (NAD+) activity
CKF48_19250	COG5609	conserved protein (DUF2294)
CKF48_19255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CKF48_19260	COG2116	formate transmembrane transporter activity
CKF48_19265	COG3424	synthase
CKF48_19270	COG1755	Isoprenylcysteine carboxyl methyltransferase
CKF48_19275	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CKF48_19290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKF48_19300	COG1533	DNA photolyase activity
CKF48_19310	COG0697	spore germination
CKF48_19315	COG0328	RNA-DNA hybrid ribonuclease activity
CKF48_19320	COG0328	RNA-DNA hybrid ribonuclease activity
CKF48_19330	COG1278	Cold shock
CKF48_19340	COG0803	Belongs to the bacterial solute-binding protein 9 family
CKF48_19350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKF48_19350	COG1321	iron dependent repressor
CKF48_19355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKF48_19365	COG1321	iron dependent repressor
CKF48_19380	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CKF48_19395	COG0488	(ABC) transporter
CKF48_19400	COG1413	lyase activity
CKF48_19420	COG2136	Putative SAM-dependent methyltransferase
CKF48_19420	COG2521	methyltransferase
CKF48_19425	COG0436	Aminotransferase
CKF48_19435	COG0861	Integral membrane protein TerC family
CKF48_19465	COG3853	Toxic anion resistance protein (TelA)
CKF48_19470	COG2310	stress, protein
CKF48_19485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CKF48_19490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKF48_19510	COG1307	EDD domain protein, DegV family
CKF48_19520	COG2755	lipolytic protein G-D-S-L family
CKF48_19535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKF48_19540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKF48_19565	COG1619	proteins homologs of microcin C7 resistance protein MccF
CKF48_19570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CKF48_19575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CKF48_19580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CKF48_19585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKF48_19590	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_19600	COG3829	transcription factor binding
CKF48_19605	COG1509	lysine 2,3-aminomutase activity
CKF48_19615	COG4479	Belongs to the UPF0346 family
CKF48_19640	COG1960	acyl-CoA dehydrogenase activity
CKF48_19650	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CKF48_19670	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_19680	COG0813	purine-nucleoside phosphorylase activity
CKF48_19685	COG1876	peptidase activity
CKF48_19695	COG0793	Belongs to the peptidase S41A family
CKF48_19695	COG3409	Peptidoglycan-binding domain 1 protein
CKF48_19700	COG2814	Major facilitator Superfamily
CKF48_19710	COG1316	TRANSCRIPTIONal
CKF48_19720	COG0523	cobalamin synthesis protein
CKF48_19745	COG0745	RESPONSE REGULATOR receiver
CKF48_19750	COG3850	Histidine kinase
CKF48_19750	COG5002	protein histidine kinase activity
CKF48_19755	COG2340	Cysteine-rich secretory protein family
CKF48_19765	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_19770	COG1231	oxidoreductase activity
CKF48_19780	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_19795	COG1228	amidohydrolase
CKF48_19810	COG2323	membrane
CKF48_19815	COG2318	DinB family
CKF48_19830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_19850	COG1609	Transcriptional regulator
CKF48_19855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKF48_19870	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKF48_19875	COG1879	ABC-type sugar transport system periplasmic component
CKF48_19900	COG0307	riboflavin synthase, alpha
CKF48_19905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKF48_19905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKF48_19910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CKF48_19915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CKF48_19925	COG3285	dna ligase
CKF48_19925	COG1793	dna ligase
CKF48_19930	COG1793	dna ligase
CKF48_19940	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CKF48_19945	COG0671	phosphoesterase, PA-phosphatase related
CKF48_19950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CKF48_19955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CKF48_19960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CKF48_19965	COG1278	Cold shock
CKF48_19970	COG0513	Belongs to the DEAD box helicase family
CKF48_20000	COG1115	amino acid carrier protein
CKF48_20005	COG1959	2 iron, 2 sulfur cluster binding
CKF48_20025	COG2608	mercury ion transmembrane transporter activity
CKF48_20030	COG2217	Heavy metal translocating P-type atpase
CKF48_20035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKF48_20040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKF48_20050	COG5002	protein histidine kinase activity
CKF48_20050	COG3850	Histidine kinase
CKF48_20080	COG1960	acyl-CoA dehydrogenase activity
CKF48_20085	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_20090	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_20095	COG1960	acyl-CoA dehydrogenase activity
CKF48_20100	COG0183	Belongs to the thiolase family
CKF48_20105	COG1024	Enoyl-CoA hydratase
CKF48_20115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKF48_20130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CKF48_20130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CKF48_20130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKF48_20135	COG2814	Major facilitator Superfamily
CKF48_20150	COG0512	Glutamine amidotransferase of anthranilate synthase
CKF48_20150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CKF48_20185	COG0753	catalase activity
CKF48_20190	COG2135	peptidase activity
CKF48_20200	COG0789	Transcriptional regulator
CKF48_20205	COG2966	Psort location CytoplasmicMembrane, score
CKF48_20215	COG1472	Belongs to the glycosyl hydrolase 3 family
CKF48_20220	COG1132	(ABC) transporter
CKF48_20225	COG3153	acetyltransferase
CKF48_20225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKF48_20240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CKF48_20245	COG3883	PFAM NLP P60 protein
CKF48_20245	COG0791	NLP P60 protein
CKF48_20250	COG2186	Transcriptional regulator
CKF48_20255	COG0277	FAD linked oxidase domain protein
CKF48_20260	COG0247	lactate metabolic process
CKF48_20265	COG0277	FAD linked oxidase domain protein
CKF48_20270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CKF48_20275	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_20280	COG1414	Transcriptional regulator
CKF48_20285	COG1620	l-lactate permease
CKF48_20295	COG2226	methyltransferase
CKF48_20300	COG1846	Transcriptional regulator
CKF48_20310	COG0183	Belongs to the thiolase family
CKF48_20320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKF48_20325	COG1183	phosphatidylcholine synthase activity
CKF48_20330	COG0322	excinuclease ABC activity
CKF48_20335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CKF48_20340	COG0573	inorganic phosphate transmembrane transporter activity
CKF48_20345	COG0581	inorganic phosphate transmembrane transporter activity
CKF48_20355	COG0243	molybdopterin cofactor binding
CKF48_20375	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CKF48_20390	COG0861	Integral membrane protein TerC family
CKF48_20395	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CKF48_20400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_20405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_20415	COG1408	metallophosphoesterase
CKF48_20430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CKF48_20435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CKF48_20435	COG0456	acetyltransferase
CKF48_20440	COG0406	alpha-ribazole phosphatase activity
CKF48_20445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CKF48_20445	COG2169	Transcriptional regulator
CKF48_20450	COG1473	amidohydrolase
CKF48_20455	COG1473	amidohydrolase
CKF48_20465	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CKF48_20475	COG1272	protein, Hemolysin III
CKF48_20480	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CKF48_20495	COG0189	ligase activity
CKF48_20505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKF48_20510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CKF48_20515	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_20520	COG0326	Molecular chaperone. Has ATPase activity
CKF48_20530	COG0493	'glutamate synthase
CKF48_20535	COG0167	dihydroorotate dehydrogenase activity
CKF48_20560	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_20565	COG1169	isochorismate synthase
CKF48_20570	COG1021	2,3-dihydroxybenzoate-AMP ligase
CKF48_20575	COG3433	isochorismatase activity
CKF48_20575	COG1535	isochorismatase
CKF48_20580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CKF48_20585	COG3251	PFAM MbtH domain protein
CKF48_20600	COG3835	regulator
CKF48_20605	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_20610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CKF48_20620	COG0385	Bile acid
CKF48_20625	COG2814	Major facilitator Superfamily
CKF48_20650	COG1510	regulation of RNA biosynthetic process
CKF48_20655	COG1125	glycine betaine transport
CKF48_20655	COG0517	IMP dehydrogenase activity
CKF48_20660	COG1174	glycine betaine transport
CKF48_20670	COG1174	glycine betaine transport
CKF48_20680	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_20685	COG1272	protein, Hemolysin III
CKF48_20695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_20730	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CKF48_20735	COG2068	MobA-Related Protein
CKF48_20760	COG2814	Major facilitator Superfamily
CKF48_20780	COG1764	response to oxidative stress
CKF48_20785	COG0708	Exodeoxyribonuclease III
CKF48_20790	COG2323	membrane
CKF48_20800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CKF48_20815	COG1051	belongs to the nudix hydrolase family
CKF48_20830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_20840	COG3227	Zinc metalloprotease (Elastase)
CKF48_20850	COG0681	Belongs to the peptidase S26 family
CKF48_20855	COG0628	permease
CKF48_20865	COG0737	Belongs to the 5'-nucleotidase family
CKF48_20880	COG3842	ATPase activity
CKF48_20885	COG1176	ABC-type spermidine putrescine transport system, permease component I
CKF48_20890	COG1177	transmembrane transport
CKF48_20895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CKF48_20915	COG4948	Mandelate Racemase Muconate Lactonizing
CKF48_20920	COG3949	Membrane
CKF48_20925	COG2861	carbohydrate metabolic process
CKF48_20935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKF48_20945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CKF48_20950	COG1845	cytochrome c oxidase, subunit III
CKF48_20960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CKF48_20975	COG0567	Dehydrogenase, E1 component
CKF48_20980	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKF48_21030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CKF48_21045	COG1268	BioY protein
CKF48_21055	COG0494	nUDIX hydrolase
CKF48_21060	COG1335	isochorismatase
CKF48_21065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CKF48_21070	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CKF48_21080	COG2340	Cysteine-rich secretory protein family
CKF48_21095	COG1917	Cupin 2, conserved barrel domain protein
CKF48_21095	COG4977	sequence-specific DNA binding
CKF48_21100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKF48_21105	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CKF48_21110	COG1228	amidohydrolase
CKF48_21120	COG2404	hydrolase activity, acting on ester bonds
CKF48_21130	COG1686	Belongs to the peptidase S11 family
CKF48_21135	COG1683	Conserved Protein
CKF48_21140	COG0488	(ABC) transporter
CKF48_21150	COG0789	Transcriptional regulator
CKF48_21155	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_21180	COG1388	LysM domain
CKF48_21180	COG3584	3D domain protein
CKF48_21190	COG2310	stress, protein
CKF48_21195	COG2310	stress, protein
CKF48_21215	COG1418	mRNA catabolic process
CKF48_21220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CKF48_21250	COG1349	DNA-binding transcription factor activity
CKF48_21255	COG3842	ATPase activity
CKF48_21280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CKF48_21290	COG1404	Belongs to the peptidase S8 family
CKF48_21300	COG2027	D-alanyl-D-alanine carboxypeptidase
CKF48_21315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_21335	COG3239	Fatty acid desaturase
CKF48_21345	COG2197	response regulator
CKF48_21350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CKF48_21365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CKF48_21375	COG0352	thiamine-phosphate diphosphorylase activity
CKF48_21375	COG0351	phosphomethylpyrimidine kinase
CKF48_21380	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CKF48_21400	COG1164	Oligoendopeptidase f
CKF48_21405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKF48_21410	COG0656	L-ascorbic acid biosynthetic process
CKF48_21430	COG0346	lactoylglutathione lyase activity
CKF48_21440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CKF48_21445	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CKF48_21460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CKF48_21465	COG1119	ATPase activity
CKF48_21470	COG1132	(ABC) transporter
CKF48_21475	COG1132	(ABC) transporter
CKF48_21490	COG1733	regulation of RNA biosynthetic process
CKF48_21515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CKF48_21520	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CKF48_21525	COG0523	cobalamin synthesis protein
CKF48_21530	COG1253	flavin adenine dinucleotide binding
CKF48_21535	COG1253	flavin adenine dinucleotide binding
CKF48_21555	COG2318	DinB family
CKF48_21570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CKF48_21575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKF48_21585	COG0803	Belongs to the bacterial solute-binding protein 9 family
CKF48_21590	COG3443	Belongs to the bacterial solute-binding protein 9 family
CKF48_21595	COG2814	Major facilitator Superfamily
CKF48_21610	COG2197	response regulator
CKF48_21620	COG2072	flavoprotein involved in K transport
CKF48_21625	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_21635	COG2226	methyltransferase
CKF48_21645	COG0745	RESPONSE REGULATOR receiver
CKF48_21650	COG2205	protein histidine kinase activity
CKF48_21655	COG0577	efflux transmembrane transporter activity
CKF48_21655	COG1136	(ABC) transporter
CKF48_21690	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CKF48_21705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CKF48_21710	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CKF48_21715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_21720	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CKF48_21725	COG4172	Belongs to the ABC transporter superfamily
CKF48_21730	COG4721	ABC-type cobalt transport system, permease component
CKF48_21755	COG1960	acyl-CoA dehydrogenase activity
CKF48_21765	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_21775	COG5609	conserved protein (DUF2294)
CKF48_21790	COG2897	thiosulfate sulfurtransferase activity
CKF48_21795	COG2186	Transcriptional regulator
CKF48_21800	COG0129	dihydroxy-acid dehydratase activity
CKF48_21825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CKF48_21845	COG0045	succinate-CoA ligase (ADP-forming) activity
CKF48_21860	COG1024	Enoyl-CoA hydratase
CKF48_21875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_21900	COG3829	transcription factor binding
CKF48_21900	COG3290	protein histidine kinase activity
CKF48_21905	COG0431	NADPH-dependent FMN reductase
CKF48_21910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CKF48_21915	COG0175	sulfate reduction
CKF48_21925	COG0529	Catalyzes the synthesis of activated sulfate
CKF48_21930	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CKF48_21955	COG0730	response to heat
CKF48_21965	COG0583	DNA-binding transcription factor activity
CKF48_21970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKF48_21980	COG0446	pyridine nucleotide-disulphide oxidoreductase
CKF48_21985	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CKF48_22030	COG0145	ligase activity
CKF48_22070	COG2072	flavoprotein involved in K transport
CKF48_22085	COG0187	DNA topoisomerase II activity
CKF48_22090	COG1832	CoA-binding protein
CKF48_22095	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKF48_22100	COG4191	Histidine kinase
CKF48_22105	COG1114	Component of the transport system for branched-chain amino acids
CKF48_22110	COG1114	Component of the transport system for branched-chain amino acids
CKF48_22115	COG1802	Transcriptional regulator
CKF48_22130	COG0824	Thioesterase
CKF48_22135	COG0464	growth
CKF48_22150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_22160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CKF48_22180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKF48_22185	COG0156	8-amino-7-oxononanoate synthase activity
CKF48_22195	COG0735	belongs to the Fur family
CKF48_22200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CKF48_22210	COG0488	(ABC) transporter
CKF48_22215	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_22225	COG3973	AAA domain
CKF48_22230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_22240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CKF48_22245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CKF48_22250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKF48_22255	COG1960	acyl-CoA dehydrogenase activity
CKF48_22260	COG1024	Enoyl-CoA hydratase
CKF48_22265	COG1960	acyl-CoA dehydrogenase activity
CKF48_22300	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_22320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CKF48_22335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKF48_22340	COG1960	acyl-CoA dehydrogenase activity
CKF48_22355	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CKF48_22365	COG1802	Transcriptional regulator
CKF48_22375	COG0473	3-isopropylmalate dehydrogenase activity
CKF48_22380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CKF48_22385	COG0390	transport system, permease component
CKF48_22405	COG1760	l-serine dehydratase
CKF48_22410	COG1760	l-serine dehydratase
CKF48_22425	COG1368	sulfuric ester hydrolase activity
CKF48_22450	COG1363	Peptidase, m42
CKF48_22455	COG1216	Glycosyl transferase, family 2
CKF48_22465	COG1216	Glycosyl transferase, family 2
CKF48_22490	COG0438	transferase activity, transferring glycosyl groups
CKF48_22500	COG1086	Polysaccharide biosynthesis protein
CKF48_22515	COG0613	PHP domain protein
CKF48_22520	COG1876	peptidase activity
CKF48_22530	COG0456	acetyltransferase
CKF48_22550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKF48_22555	COG1116	anion transmembrane transporter activity
CKF48_22560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_22565	COG0604	alcohol dehydrogenase
CKF48_22570	COG4326	sporulation control protein
CKF48_22580	COG1024	Enoyl-CoA hydratase
CKF48_22590	COG1960	acyl-CoA dehydrogenase activity
CKF48_22595	COG0791	NLP P60 protein
CKF48_22595	COG1388	LysM domain
CKF48_22600	COG5522	Integral membrane protein (intg_mem_TP0381)
CKF48_22605	COG2130	NADP-dependent
CKF48_22615	COG0410	ABC transporter
CKF48_22630	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKF48_22635	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_22640	COG1024	Enoyl-CoA hydratase
CKF48_22665	COG0183	Belongs to the thiolase family
CKF48_22670	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_22690	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_22695	COG1960	acyl-CoA dehydrogenase activity
CKF48_22705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKF48_22720	COG0454	-acetyltransferase
CKF48_22735	COG0420	3'-5' exonuclease activity
CKF48_22740	COG1278	Cold shock
CKF48_22765	COG0281	malic enzyme
CKF48_22790	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CKF48_22800	COG0028	Belongs to the TPP enzyme family
CKF48_22805	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_22825	COG1414	Transcriptional regulator
CKF48_22830	COG2267	carboxylic ester hydrolase activity
CKF48_22835	COG4876	unkown
CKF48_22840	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_22845	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_22850	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CKF48_22855	COG1960	acyl-CoA dehydrogenase activity
CKF48_22860	COG2204	response regulator
CKF48_22875	COG1960	acyl-CoA dehydrogenase activity
CKF48_22965	COG0741	lytic transglycosylase activity
CKF48_22965	COG0791	NLP P60 protein
CKF48_23035	COG2002	toxin-antitoxin pair type II binding
CKF48_23045	COG2003	Belongs to the UPF0758 family
CKF48_23100	COG1309	transcriptional regulator
CKF48_23125	COG1595	DNA-templated transcription, initiation
CKF48_23135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKF48_23165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CKF48_23190	COG1136	(ABC) transporter
CKF48_23215	COG0500	methyltransferase
CKF48_23215	COG3615	Tellurite resistance protein tehB
CKF48_23225	COG2819	hydrolase of the alpha beta superfamily
CKF48_23250	COG1132	(ABC) transporter
CKF48_23300	COG2003	Belongs to the UPF0758 family
CKF48_23320	COG0653	protein targeting
CKF48_23365	COG0406	alpha-ribazole phosphatase activity
CKF48_23385	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_23390	COG1733	regulation of RNA biosynthetic process
CKF48_23395	COG1472	Belongs to the glycosyl hydrolase 3 family
CKF48_23405	COG2267	carboxylic ester hydrolase activity
CKF48_23410	COG1846	Transcriptional regulator
CKF48_23430	COG1733	regulation of RNA biosynthetic process
CKF48_23470	COG2002	toxin-antitoxin pair type II binding
CKF48_23495	COG1595	DNA-templated transcription, initiation
CKF48_23520	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CKF48_23530	COG0697	spore germination
CKF48_23555	COG3223	Belongs to the PsiE family
CKF48_23560	COG2427	Protein of unknown function (DUF1641)
CKF48_23565	COG3383	formate dehydrogenase (NAD+) activity