locus-tag	class	description
BkAM31D_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BkAM31D_00010	COG0592	DNA-directed DNA polymerase activity
BkAM31D_00015	COG2501	S4 domain
BkAM31D_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BkAM31D_00030	COG0187	DNA topoisomerase II activity
BkAM31D_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BkAM31D_00065	COG0516	GMP reductase activity
BkAM31D_00065	COG0517	IMP dehydrogenase activity
BkAM31D_00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BkAM31D_00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BkAM31D_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BkAM31D_00095	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_00100	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_00115	COG0747	negative chemotaxis
BkAM31D_00125	COG0590	tRNA wobble adenosine to inosine editing
BkAM31D_00145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BkAM31D_00150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BkAM31D_00155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BkAM31D_00195	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_00200	COG1982	Orn Lys Arg decarboxylase major
BkAM31D_00205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BkAM31D_00210	COG3870	Protein conserved in bacteria
BkAM31D_00215	COG0470	DNA polymerase III
BkAM31D_00220	COG1774	PSP1 C-terminal conserved region
BkAM31D_00225	COG4467	Involved in initiation control of chromosome replication
BkAM31D_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BkAM31D_00235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BkAM31D_00240	COG2002	toxin-antitoxin pair type II binding
BkAM31D_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BkAM31D_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BkAM31D_00265	COG0084	hydrolase, TatD family'
BkAM31D_00270	COG3583	domain protein
BkAM31D_00270	COG3584	3D domain protein
BkAM31D_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BkAM31D_00290	COG4466	Protein conserved in bacteria
BkAM31D_00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BkAM31D_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BkAM31D_00310	COG0251	oxidation-reduction process
BkAM31D_00315	COG2088	sporulation resulting in formation of a cellular spore
BkAM31D_00320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BkAM31D_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BkAM31D_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BkAM31D_00335	COG0193	aminoacyl-tRNA hydrolase activity
BkAM31D_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BkAM31D_00350	COG2002	toxin-antitoxin pair type II binding
BkAM31D_00355	COG2244	polysaccharide biosynthetic process
BkAM31D_00360	COG3956	TIGRFAM MazG family protein
BkAM31D_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BkAM31D_00385	COG1098	S1 RNA binding domain
BkAM31D_00395	COG2208	phosphoserine phosphatase activity
BkAM31D_00400	COG2304	oxidoreductase activity
BkAM31D_00430	COG0037	tRNA processing
BkAM31D_00445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BkAM31D_00450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BkAM31D_00455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BkAM31D_00460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BkAM31D_00465	COG2323	membrane
BkAM31D_00470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BkAM31D_00475	COG0512	Glutamine amidotransferase of anthranilate synthase
BkAM31D_00480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BkAM31D_00485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BkAM31D_00490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BkAM31D_00495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BkAM31D_00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BkAM31D_00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BkAM31D_00525	COG2801	Transposase and inactivated derivatives
BkAM31D_00560	COG3880	PFAM UvrB UvrC protein
BkAM31D_00565	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BkAM31D_00570	COG0542	response to heat
BkAM31D_00575	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BkAM31D_00580	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BkAM31D_00585	COG4956	integral membrane protein (PIN domain superfamily)
BkAM31D_00590	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BkAM31D_00595	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BkAM31D_00600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BkAM31D_00610	COG1045	serine acetyltransferase
BkAM31D_00615	COG0215	cysteine-tRNA ligase activity
BkAM31D_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BkAM31D_00630	COG3688	RNA-binding protein containing a PIN domain
BkAM31D_00640	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BkAM31D_00645	COG0250	Participates in transcription elongation, termination and antitermination
BkAM31D_00650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BkAM31D_00655	COG0081	regulation of translation
BkAM31D_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BkAM31D_00670	COG0222	ribosome binding
BkAM31D_00675	COG2813	Specifically methylates the guanine in position
BkAM31D_00680	COG0085	RNA polymerase activity
BkAM31D_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BkAM31D_00690	COG1358	cellular component organization or biogenesis
BkAM31D_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BkAM31D_00700	COG0049	tRNA binding
BkAM31D_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BkAM31D_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BkAM31D_00720	COG0051	transcription antitermination factor activity, RNA binding
BkAM31D_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BkAM31D_00730	COG0088	Forms part of the polypeptide exit tunnel
BkAM31D_00735	COG0089	rRNA binding
BkAM31D_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BkAM31D_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BkAM31D_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BkAM31D_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BkAM31D_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BkAM31D_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
BkAM31D_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BkAM31D_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BkAM31D_00780	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BkAM31D_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BkAM31D_00790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BkAM31D_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BkAM31D_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BkAM31D_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BkAM31D_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BkAM31D_00815	COG1841	ribosomal large subunit assembly
BkAM31D_00820	COG0200	Binds to the 23S rRNA
BkAM31D_00825	COG0201	protein transport
BkAM31D_00830	COG0563	adenylate kinase activity
BkAM31D_00835	COG0024	Methionine aminopeptidase
BkAM31D_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BkAM31D_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BkAM31D_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BkAM31D_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BkAM31D_00865	COG0202	RNA polymerase activity
BkAM31D_00870	COG0203	ribosomal protein L17
BkAM31D_00875	COG1122	ATPase activity
BkAM31D_00880	COG1122	ATPase activity
BkAM31D_00885	COG1122	ATPase activity
BkAM31D_00895	COG0101	tRNA pseudouridine synthase activity
BkAM31D_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BkAM31D_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BkAM31D_00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_00935	COG0489	protein tyrosine kinase activity
BkAM31D_00945	COG2194	sulfuric ester hydrolase activity
BkAM31D_00950	COG0726	polysaccharide deacetylase
BkAM31D_01030	COG1595	DNA-templated transcription, initiation
BkAM31D_01035	COG5662	AntiSigma factor
BkAM31D_01040	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BkAM31D_01045	COG4856	YbbR-like protein
BkAM31D_01050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BkAM31D_01060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BkAM31D_01070	COG1309	transcriptional regulator
BkAM31D_01075	COG0655	NAD(P)H dehydrogenase (quinone) activity
BkAM31D_01100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_01105	COG2223	nitrite transmembrane transporter activity
BkAM31D_01110	COG2190	(PTS) system
BkAM31D_01110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_01110	COG1263	PTS System
BkAM31D_01120	COG0596	Alpha beta hydrolase
BkAM31D_01125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BkAM31D_01130	COG0243	molybdopterin cofactor binding
BkAM31D_01145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BkAM31D_01145	COG1587	Uroporphyrinogen-III synthase
BkAM31D_01150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BkAM31D_01155	COG2146	nitrite reductase [NAD(P)H] activity
BkAM31D_01185	COG1587	Uroporphyrinogen-III synthase
BkAM31D_01190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BkAM31D_01195	COG1984	allophanate hydrolase subunit 2
BkAM31D_01200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BkAM31D_01210	COG2885	chlorophyll binding
BkAM31D_01230	COG1733	regulation of RNA biosynthetic process
BkAM31D_01235	COG0589	response to stress
BkAM31D_01250	COG2239	Acts as a magnesium transporter
BkAM31D_01270	COG1178	ABC-type Fe3 transport system permease component
BkAM31D_01285	COG0803	Belongs to the bacterial solute-binding protein 9 family
BkAM31D_01290	COG0705	Rhomboid family
BkAM31D_01295	COG0736	holo-[acyl-carrier-protein] synthase activity
BkAM31D_01300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BkAM31D_01305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BkAM31D_01310	COG0864	Transcriptional regulator
BkAM31D_01315	COG2337	Toxic component of a toxin-antitoxin (TA) module
BkAM31D_01320	COG1366	Belongs to the anti-sigma-factor antagonist family
BkAM31D_01325	COG1366	Belongs to the anti-sigma-factor antagonist family
BkAM31D_01330	COG2172	sigma factor antagonist activity
BkAM31D_01335	COG2208	phosphoserine phosphatase activity
BkAM31D_01345	COG2172	sigma factor antagonist activity
BkAM31D_01370	COG2183	response to ionizing radiation
BkAM31D_01380	COG3091	SprT-like family
BkAM31D_01465	COG0586	Pfam SNARE associated Golgi protein
BkAM31D_01470	COG2239	Acts as a magnesium transporter
BkAM31D_01475	COG0626	cystathionine gamma-synthase activity
BkAM31D_01490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BkAM31D_01495	COG0802	atpase or kinase
BkAM31D_01500	COG1214	PFAM Peptidase M22, glycoprotease
BkAM31D_01505	COG0456	acetyltransferase
BkAM31D_01510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BkAM31D_01530	COG0488	(ABC) transporter
BkAM31D_01535	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BkAM31D_01540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BkAM31D_01545	COG0805	protein transport
BkAM31D_01555	COG2814	Major facilitator Superfamily
BkAM31D_01565	COG1266	CAAX protease self-immunity
BkAM31D_01570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BkAM31D_01575	COG0459	protein refolding
BkAM31D_01580	COG1609	Transcriptional regulator
BkAM31D_01590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_01595	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_01605	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BkAM31D_01615	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_01620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BkAM31D_01625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BkAM31D_01635	COG1929	Belongs to the glycerate kinase type-1 family
BkAM31D_01640	COG1929	Belongs to the glycerate kinase type-1 family
BkAM31D_01645	COG1929	Belongs to the glycerate kinase type-1 family
BkAM31D_01650	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BkAM31D_01680	COG0601	transmembrane transport
BkAM31D_01695	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_01700	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_01705	COG0534	Mate efflux family protein
BkAM31D_01720	COG3119	arylsulfatase activity
BkAM31D_01725	COG1181	Belongs to the D-alanine--D-alanine ligase family
BkAM31D_01730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BkAM31D_01740	COG2972	Histidine kinase
BkAM31D_01745	COG2207	Transcriptional regulator
BkAM31D_01745	COG4753	response regulator
BkAM31D_01760	COG1368	sulfuric ester hydrolase activity
BkAM31D_01770	COG0189	ligase activity
BkAM31D_01785	COG3290	protein histidine kinase activity
BkAM31D_01790	COG4565	transcriptional regulatory protein
BkAM31D_01795	COG2851	Citrate transporter
BkAM31D_01800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BkAM31D_01805	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BkAM31D_01810	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BkAM31D_01815	COG2404	hydrolase activity, acting on ester bonds
BkAM31D_01825	COG0714	Associated with various cellular activities
BkAM31D_01830	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BkAM31D_01835	COG1305	Transglutaminase-like
BkAM31D_01845	COG0519	Catalyzes the synthesis of GMP from XMP
BkAM31D_01845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BkAM31D_01855	COG2252	PERMEase
BkAM31D_01885	COG3424	synthase
BkAM31D_01890	COG1755	Isoprenylcysteine carboxyl methyltransferase
BkAM31D_01905	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BkAM31D_01910	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BkAM31D_01915	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BkAM31D_01920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BkAM31D_01925	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BkAM31D_01930	COG0047	phosphoribosylformylglycinamidine synthase activity
BkAM31D_01935	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BkAM31D_01940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BkAM31D_01945	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BkAM31D_01950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BkAM31D_01955	COG0138	bifunctional purine biosynthesis protein purh
BkAM31D_01960	COG0151	Belongs to the GarS family
BkAM31D_01975	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BkAM31D_01980	COG1470	cell adhesion involved in biofilm formation
BkAM31D_01985	COG4496	protein, YerC YecD
BkAM31D_01990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BkAM31D_01995	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BkAM31D_01995	COG2508	Transcriptional regulator
BkAM31D_02015	COG0393	Putative heavy-metal-binding
BkAM31D_02025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BkAM31D_02030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BkAM31D_02045	COG0210	DNA helicase
BkAM31D_02050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BkAM31D_02055	COG4851	CamS sex pheromone cAM373 precursor
BkAM31D_02060	COG1744	ABC transporter substrate-binding protein PnrA-like
BkAM31D_02085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BkAM31D_02095	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BkAM31D_02100	COG0154	amidase activity
BkAM31D_02105	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BkAM31D_02110	COG1597	lipid kinase activity
BkAM31D_02115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BkAM31D_02120	COG0582	viral genome integration into host DNA
BkAM31D_02135	COG3620	sequence-specific DNA binding
BkAM31D_02200	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BkAM31D_02230	COG3561	AntA/AntB antirepressor
BkAM31D_02290	COG0629	single-stranded DNA binding
BkAM31D_02360	COG5484	DNA packaging
BkAM31D_02360	COG3728	DNA packaging
BkAM31D_02505	COG3655	Transcriptional regulator
BkAM31D_02510	COG4974	Belongs to the 'phage' integrase family
BkAM31D_02575	COG1063	alcohol dehydrogenase
BkAM31D_02585	COG1609	Transcriptional regulator
BkAM31D_02590	COG0366	Alpha amylase catalytic
BkAM31D_02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_02595	COG1263	PTS System
BkAM31D_02600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_02600	COG1263	PTS System
BkAM31D_02605	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_02610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BkAM31D_02635	COG1937	Protein conserved in bacteria
BkAM31D_02640	COG2210	Belongs to the sulfur carrier protein TusA family
BkAM31D_02655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_02655	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_02660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_02660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_02665	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_02670	COG0730	response to heat
BkAM31D_02675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BkAM31D_02680	COG3273	potassium ion transport
BkAM31D_02680	COG0471	metal ion transport
BkAM31D_02685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BkAM31D_02710	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BkAM31D_02730	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BkAM31D_02745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BkAM31D_02750	COG0156	8-amino-7-oxononanoate synthase activity
BkAM31D_02755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BkAM31D_02760	COG2124	cytochrome p450
BkAM31D_02770	COG3239	Fatty acid desaturase
BkAM31D_02775	COG4585	Histidine kinase
BkAM31D_02780	COG2197	response regulator
BkAM31D_02785	COG0028	Belongs to the TPP enzyme family
BkAM31D_02790	COG0583	DNA-binding transcription factor activity
BkAM31D_02795	COG4948	Mandelate Racemase Muconate Lactonizing
BkAM31D_02800	COG3181	Tripartite tricarboxylate transporter family receptor
BkAM31D_02815	COG4565	transcriptional regulatory protein
BkAM31D_02820	COG3290	protein histidine kinase activity
BkAM31D_02825	COG0039	L-malate dehydrogenase activity
BkAM31D_02830	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_02855	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_02865	COG0659	secondary active sulfate transmembrane transporter activity
BkAM31D_02870	COG3835	regulator
BkAM31D_02880	COG3135	benzoate transporter
BkAM31D_02885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_02905	COG0411	ABC transporter
BkAM31D_02920	COG1141	Ferredoxin
BkAM31D_02925	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_02930	COG1024	Enoyl-CoA hydratase
BkAM31D_02950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BkAM31D_02965	COG1024	Enoyl-CoA hydratase
BkAM31D_02975	COG1024	Enoyl-CoA hydratase
BkAM31D_02980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_03010	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_03015	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_03020	COG0183	Belongs to the thiolase family
BkAM31D_03030	COG1024	Enoyl-CoA hydratase
BkAM31D_03040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_03055	COG2814	Major facilitator Superfamily
BkAM31D_03070	COG0681	Belongs to the peptidase S26 family
BkAM31D_03080	COG3706	GGDEF domain
BkAM31D_03085	COG1271	oxidase subunit
BkAM31D_03090	COG1294	oxidase, subunit
BkAM31D_03100	COG4988	ABC transporter
BkAM31D_03105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BkAM31D_03115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BkAM31D_03120	COG0840	transmembrane signaling receptor activity
BkAM31D_03135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BkAM31D_03140	COG2080	2 iron, 2 sulfur cluster binding
BkAM31D_03145	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BkAM31D_03155	COG2508	Transcriptional regulator
BkAM31D_03160	COG3195	allantoin biosynthetic process
BkAM31D_03160	COG3648	Uricase
BkAM31D_03165	COG2351	hydroxyisourate hydrolase activity
BkAM31D_03170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BkAM31D_03180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BkAM31D_03205	COG1129	ABC transporter
BkAM31D_03210	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_03215	COG1132	(ABC) transporter
BkAM31D_03220	COG1132	(ABC) transporter
BkAM31D_03225	COG0405	Gamma-glutamyltransferase
BkAM31D_03230	COG0405	Gamma-glutamyltransferase
BkAM31D_03235	COG2059	Chromate
BkAM31D_03240	COG2059	Chromate
BkAM31D_03255	COG2244	polysaccharide biosynthetic process
BkAM31D_03260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_03260	COG1263	PTS System
BkAM31D_03265	COG0366	Alpha amylase catalytic
BkAM31D_03270	COG0366	Alpha amylase catalytic
BkAM31D_03275	COG0366	Alpha amylase catalytic
BkAM31D_03280	COG2188	Transcriptional regulator
BkAM31D_03285	COG0386	Belongs to the glutathione peroxidase family
BkAM31D_03290	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BkAM31D_03295	COG0488	(ABC) transporter
BkAM31D_03300	COG1349	DNA-binding transcription factor activity
BkAM31D_03305	COG1105	Belongs to the carbohydrate kinase PfkB family
BkAM31D_03310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BkAM31D_03310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BkAM31D_03310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BkAM31D_03320	COG0154	amidase activity
BkAM31D_03335	COG3859	Proton-coupled thiamine transporter YuaJ
BkAM31D_03345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BkAM31D_03350	COG1077	Cell shape determining protein MreB Mrl
BkAM31D_03355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_03355	COG2190	(PTS) system
BkAM31D_03355	COG1263	PTS System
BkAM31D_03360	COG3711	transcriptional antiterminator
BkAM31D_03390	COG0328	RNA-DNA hybrid ribonuclease activity
BkAM31D_03390	COG3341	Caulimovirus viroplasmin
BkAM31D_03405	COG1522	sequence-specific DNA binding
BkAM31D_03415	COG0217	transcriptional regulatory protein
BkAM31D_03420	COG1294	oxidase, subunit
BkAM31D_03425	COG1271	oxidase subunit
BkAM31D_03440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_03450	COG0477	Major facilitator Superfamily
BkAM31D_03460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_03465	COG2364	Membrane
BkAM31D_03480	COG0535	radical SAM domain protein
BkAM31D_03490	COG0406	alpha-ribazole phosphatase activity
BkAM31D_03510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BkAM31D_03525	COG4989	oxidoreductase activity
BkAM31D_03535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BkAM31D_03545	COG1917	Cupin 2, conserved barrel domain protein
BkAM31D_03550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BkAM31D_03555	COG0456	acetyltransferase
BkAM31D_03570	COG1090	epimerase
BkAM31D_03575	COG2137	regulation of response to DNA damage stimulus
BkAM31D_03580	COG1620	l-lactate permease
BkAM31D_03605	COG1988	membrane-bound metal-dependent
BkAM31D_03615	COG1194	a g-specific adenine glycosylase
BkAM31D_03620	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_03630	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_03630	COG0604	alcohol dehydrogenase
BkAM31D_03630	COG3321	synthase
BkAM31D_03645	COG3557	Belongs to the UPF0374 family
BkAM31D_03650	COG1132	(ABC) transporter
BkAM31D_03655	COG4129	membrane
BkAM31D_03660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BkAM31D_03670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BkAM31D_03675	COG3870	Protein conserved in bacteria
BkAM31D_03680	COG0735	belongs to the Fur family
BkAM31D_03795	COG4974	Belongs to the 'phage' integrase family
BkAM31D_03825	COG4695	Portal protein
BkAM31D_03890	COG2433	Pfam Transposase IS66
BkAM31D_03905	COG2801	Transposase and inactivated derivatives
BkAM31D_03915	COG0179	Fumarylacetoacetate (FAA) hydrolase
BkAM31D_03935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BkAM31D_03940	COG2188	Transcriptional regulator
BkAM31D_03945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BkAM31D_03970	COG0295	cytidine deaminase activity
BkAM31D_03975	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BkAM31D_03985	COG3764	Sortase (surface protein transpeptidase)
BkAM31D_03990	COG0746	molybdenum cofactor guanylyltransferase activity
BkAM31D_03995	COG0521	Mo-molybdopterin cofactor biosynthetic process
BkAM31D_04000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BkAM31D_04005	COG0303	'Molybdopterin
BkAM31D_04010	COG1763	Mo-molybdopterin cofactor biosynthetic process
BkAM31D_04015	COG0314	molybdopterin synthase activity
BkAM31D_04020	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BkAM31D_04030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BkAM31D_04040	COG5609	conserved protein (DUF2294)
BkAM31D_04050	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BkAM31D_04055	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BkAM31D_04060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BkAM31D_04085	COG0783	Belongs to the Dps family
BkAM31D_04090	COG3382	B3 4 domain protein
BkAM31D_04095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BkAM31D_04100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BkAM31D_04110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BkAM31D_04130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BkAM31D_04135	COG2766	serine protein kinase
BkAM31D_04145	COG2718	Belongs to the UPF0229 family
BkAM31D_04155	COG5002	protein histidine kinase activity
BkAM31D_04160	COG0673	inositol 2-dehydrogenase activity
BkAM31D_04180	COG1846	Transcriptional regulator
BkAM31D_04185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_04190	COG4605	iron ion homeostasis
BkAM31D_04195	COG4604	ABC transporter, ATP-binding protein
BkAM31D_04200	COG4607	ABC-type enterochelin transport system periplasmic component
BkAM31D_04210	COG0436	Aminotransferase
BkAM31D_04215	COG3546	catalase activity
BkAM31D_04220	COG0584	glycerophosphoryl diester phosphodiesterase
BkAM31D_04230	COG0058	SHG alpha-glucan phosphorylase activity
BkAM31D_04235	COG0297	glycogen (starch) synthase activity
BkAM31D_04240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BkAM31D_04245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BkAM31D_04255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BkAM31D_04255	COG3153	acetyltransferase
BkAM31D_04265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BkAM31D_04270	COG2719	SpoVR family
BkAM31D_04275	COG0745	RESPONSE REGULATOR receiver
BkAM31D_04280	COG3850	Histidine kinase
BkAM31D_04280	COG5002	protein histidine kinase activity
BkAM31D_04285	COG3212	peptidase
BkAM31D_04290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BkAM31D_04295	COG0733	neurotransmitter:sodium symporter activity
BkAM31D_04305	COG1704	LemA family
BkAM31D_04310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BkAM31D_04315	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_04320	COG0439	Biotin carboxylase
BkAM31D_04325	COG0511	ligase activity, forming carbon-carbon bonds
BkAM31D_04330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BkAM31D_04335	COG1024	Enoyl-CoA hydratase
BkAM31D_04340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BkAM31D_04345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BkAM31D_04350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BkAM31D_04395	COG0561	phosphatase activity
BkAM31D_04400	COG1368	sulfuric ester hydrolase activity
BkAM31D_04420	COG0745	RESPONSE REGULATOR receiver
BkAM31D_04425	COG2205	protein histidine kinase activity
BkAM31D_04425	COG2770	Histidine kinase
BkAM31D_04430	COG3481	metal-dependent phosphohydrolase, HD sub domain
BkAM31D_04440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BkAM31D_04460	COG1846	Transcriptional regulator
BkAM31D_04480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BkAM31D_04485	COG0537	adenosine 5'-monophosphoramidase activity
BkAM31D_04490	COG1131	(ABC) transporter
BkAM31D_04495	COG4473	ABC transporter
BkAM31D_04505	COG0785	Cytochrome C biogenesis protein
BkAM31D_04515	COG1842	Phage shock protein A
BkAM31D_04525	COG4758	membrane
BkAM31D_04530	COG4585	Histidine kinase
BkAM31D_04535	COG2197	response regulator
BkAM31D_04540	COG2329	Antibiotic biosynthesis monooxygenase
BkAM31D_04545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BkAM31D_04550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BkAM31D_04580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BkAM31D_04585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BkAM31D_04595	COG3290	protein histidine kinase activity
BkAM31D_04600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BkAM31D_04605	COG4492	Belongs to the UPF0735 family
BkAM31D_04610	COG0077	Prephenate dehydratase
BkAM31D_04615	COG1827	regulation of RNA biosynthetic process
BkAM31D_04620	COG1104	cysteine desulfurase activity
BkAM31D_04625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BkAM31D_04630	COG0157	Belongs to the NadC ModD family
BkAM31D_04640	COG1388	LysM domain
BkAM31D_04655	COG0632	four-way junction helicase activity
BkAM31D_04660	COG2255	four-way junction helicase activity
BkAM31D_04670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BkAM31D_04675	COG0343	queuine tRNA-ribosyltransferase activity
BkAM31D_04685	COG1862	Preprotein translocase
BkAM31D_04695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BkAM31D_04700	COG2323	membrane
BkAM31D_04705	COG2244	polysaccharide biosynthetic process
BkAM31D_04730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BkAM31D_04730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BkAM31D_04735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BkAM31D_04740	COG5416	Lipopolysaccharide assembly protein A domain
BkAM31D_04745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BkAM31D_04745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BkAM31D_04750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BkAM31D_04755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BkAM31D_04760	COG1490	D-aminoacyl-tRNA deacylase activity
BkAM31D_04775	COG0124	histidyl-tRNA synthetase
BkAM31D_04780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BkAM31D_04790	COG0460	homoserine dehydrogenase
BkAM31D_04805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BkAM31D_04810	COG1620	l-lactate permease
BkAM31D_04815	COG0247	lactate metabolic process
BkAM31D_04820	COG1139	Iron-sulfur cluster binding protein
BkAM31D_04825	COG1556	Lactate utilization protein
BkAM31D_04845	COG2364	Membrane
BkAM31D_04850	COG1959	2 iron, 2 sulfur cluster binding
BkAM31D_04855	COG1104	cysteine desulfurase activity
BkAM31D_04875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BkAM31D_04890	COG0628	permease
BkAM31D_04900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BkAM31D_04905	COG4472	Bacterial protein of unknown function (DUF965)
BkAM31D_04910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BkAM31D_04915	COG3906	Belongs to the UPF0473 family
BkAM31D_04920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BkAM31D_04940	COG0572	uridine kinase
BkAM31D_04945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BkAM31D_04960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BkAM31D_04970	COG0494	nUDIX hydrolase
BkAM31D_04990	COG1191	sigma factor activity
BkAM31D_04995	COG2239	Acts as a magnesium transporter
BkAM31D_05000	COG1285	pathogenesis
BkAM31D_05005	COG2239	Acts as a magnesium transporter
BkAM31D_05025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BkAM31D_05030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BkAM31D_05045	COG4191	Histidine kinase
BkAM31D_05050	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_05055	COG1966	Carbon starvation protein
BkAM31D_05065	COG0776	regulation of translation
BkAM31D_05075	COG0688	phosphatidylethanolamine metabolic process
BkAM31D_05080	COG3835	regulator
BkAM31D_05095	COG0247	lactate metabolic process
BkAM31D_05145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BkAM31D_05150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BkAM31D_05155	COG1534	Rna-binding protein
BkAM31D_05160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BkAM31D_05165	COG1713	HD superfamily hydrolase involved in NAD metabolism
BkAM31D_05170	COG0799	negative regulation of ribosome biogenesis
BkAM31D_05180	COG2226	methyltransferase
BkAM31D_05185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BkAM31D_05195	COG1555	photosystem II stabilization
BkAM31D_05195	COG1596	polysaccharide export
BkAM31D_05200	COG2131	deaminase
BkAM31D_05220	COG1466	dna polymerase III delta subunit
BkAM31D_05225	COG0268	Binds directly to 16S ribosomal RNA
BkAM31D_05230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BkAM31D_05235	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_05250	COG0481	GTPase activity
BkAM31D_05255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BkAM31D_05260	COG1420	regulation of RNA biosynthetic process
BkAM31D_05265	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BkAM31D_05270	COG0443	Heat shock 70 kDa protein
BkAM31D_05275	COG0484	heat shock protein binding
BkAM31D_05280	COG2264	protein methyltransferase activity
BkAM31D_05285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BkAM31D_05290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BkAM31D_05295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BkAM31D_05300	COG2205	protein histidine kinase activity
BkAM31D_05315	COG1283	sodium-dependent phosphate transmembrane transporter activity
BkAM31D_05325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BkAM31D_05330	COG1610	YqeY-like protein
BkAM31D_05345	COG4864	UPF0365 protein
BkAM31D_05365	COG1702	phosphate starvation-inducible protein PhoH
BkAM31D_05370	COG1480	7TM receptor with intracellular HD hydrolase
BkAM31D_05380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BkAM31D_05390	COG0295	cytidine deaminase activity
BkAM31D_05395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BkAM31D_05405	COG1381	Involved in DNA repair and RecF pathway recombination
BkAM31D_05415	COG0752	glycyl-tRNA synthetase alpha subunit
BkAM31D_05420	COG0751	glycine-tRNA ligase activity
BkAM31D_05425	COG0517	IMP dehydrogenase activity
BkAM31D_05430	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BkAM31D_05435	COG1671	Belongs to the UPF0178 family
BkAM31D_05440	COG0358	DNA primase activity
BkAM31D_05445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BkAM31D_05455	COG2010	Cytochrome c
BkAM31D_05460	COG2384	SAM-dependent methyltransferase
BkAM31D_05465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BkAM31D_05470	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BkAM31D_05490	COG0513	Belongs to the DEAD box helicase family
BkAM31D_05495	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BkAM31D_05505	COG5002	protein histidine kinase activity
BkAM31D_05525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BkAM31D_05530	COG0248	Ppx GppA phosphatase
BkAM31D_05535	COG1121	(ABC) transporter
BkAM31D_05540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BkAM31D_05545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BkAM31D_05550	COG0735	belongs to the Fur family
BkAM31D_05565	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BkAM31D_05570	COG4709	membrane
BkAM31D_05575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BkAM31D_05585	COG2814	Major facilitator Superfamily
BkAM31D_05590	COG4086	secreted protein
BkAM31D_05605	COG1283	sodium-dependent phosphate transmembrane transporter activity
BkAM31D_05635	COG1968	undecaprenyl-diphosphatase activity
BkAM31D_05640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BkAM31D_05645	COG0477	Major facilitator Superfamily
BkAM31D_05675	COG1543	Belongs to the glycosyl hydrolase 57 family
BkAM31D_05680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BkAM31D_05690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BkAM31D_05695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BkAM31D_05705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BkAM31D_05720	COG0457	Tetratricopeptide repeat
BkAM31D_05720	COG0705	Rhomboid family
BkAM31D_05730	COG0697	spore germination
BkAM31D_05750	COG1940	carbohydrate kinase activity
BkAM31D_05755	COG1027	Aspartate ammonia-lyase
BkAM31D_05770	COG0352	thiamine-phosphate diphosphorylase activity
BkAM31D_05780	COG2022	thiamine diphosphate biosynthetic process
BkAM31D_05785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BkAM31D_05790	COG0351	phosphomethylpyrimidine kinase
BkAM31D_05800	COG0011	TIGRFAM Protein of
BkAM31D_05805	COG2153	protein acetylation
BkAM31D_05810	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BkAM31D_05815	COG2382	esterase
BkAM31D_05825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BkAM31D_05870	COG3546	catalase activity
BkAM31D_05875	COG0730	response to heat
BkAM31D_05885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BkAM31D_05890	COG0765	amino acid transport
BkAM31D_05895	COG1126	abc transporter atp-binding protein
BkAM31D_05900	COG4129	membrane
BkAM31D_05905	COG1376	ErfK ybiS ycfS ynhG family protein
BkAM31D_05920	COG2195	Cleaves the N-terminal amino acid of tripeptides
BkAM31D_05925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BkAM31D_05935	COG2257	FlhB HrpN YscU SpaS Family
BkAM31D_05950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BkAM31D_05955	COG1728	Protein conserved in bacteria
BkAM31D_05990	COG0175	sulfate reduction
BkAM31D_05995	COG2046	Belongs to the sulfate adenylyltransferase family
BkAM31D_06000	COG0306	phosphate transporter
BkAM31D_06005	COG0529	Catalyzes the synthesis of activated sulfate
BkAM31D_06010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BkAM31D_06030	COG2861	carbohydrate metabolic process
BkAM31D_06035	COG0789	Transcriptional regulator
BkAM31D_06040	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BkAM31D_06040	COG1587	Uroporphyrinogen-III synthase
BkAM31D_06055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BkAM31D_06060	COG1469	GTP cyclohydrolase I activity
BkAM31D_06070	COG0527	aspartate kinase activity
BkAM31D_06090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BkAM31D_06095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BkAM31D_06105	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_06110	COG0300	oxidoreductase activity
BkAM31D_06130	COG0367	asparagine synthase
BkAM31D_06140	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_06150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BkAM31D_06165	COG2190	(PTS) system
BkAM31D_06170	COG3711	transcriptional antiterminator
BkAM31D_06175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BkAM31D_06185	COG1966	Carbon starvation protein
BkAM31D_06195	COG0701	Predicted permease
BkAM31D_06200	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BkAM31D_06210	COG0702	epimerase
BkAM31D_06220	COG1968	undecaprenyl-diphosphatase activity
BkAM31D_06225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_06245	COG1379	DNA repair
BkAM31D_06250	COG1300	Membrane
BkAM31D_06255	COG0735	belongs to the Fur family
BkAM31D_06265	COG4974	Belongs to the 'phage' integrase family
BkAM31D_06270	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BkAM31D_06290	COG5609	conserved protein (DUF2294)
BkAM31D_06300	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_06305	COG1376	ErfK ybiS ycfS ynhG family protein
BkAM31D_06310	COG3093	addiction module antidote protein HigA
BkAM31D_06330	COG5002	protein histidine kinase activity
BkAM31D_06345	COG1764	response to oxidative stress
BkAM31D_06360	COG1686	Belongs to the peptidase S11 family
BkAM31D_06370	COG2172	sigma factor antagonist activity
BkAM31D_06380	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BkAM31D_06385	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BkAM31D_06395	COG1850	ribulose-bisphosphate carboxylase activity
BkAM31D_06400	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BkAM31D_06405	COG0235	Class ii aldolase
BkAM31D_06410	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BkAM31D_06415	COG0367	asparagine synthase
BkAM31D_06425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_06440	COG0697	spore germination
BkAM31D_06445	COG0019	diaminopimelate decarboxylase activity
BkAM31D_06460	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_06465	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BkAM31D_06470	COG1904	glucuronate isomerase
BkAM31D_06475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BkAM31D_06480	COG2755	lipolytic protein G-D-S-L family
BkAM31D_06495	COG2207	Transcriptional regulator
BkAM31D_06505	COG1653	transport
BkAM31D_06510	COG4209	transmembrane transport
BkAM31D_06515	COG0395	ABC-type sugar transport system, permease component
BkAM31D_06525	COG0477	Major facilitator Superfamily
BkAM31D_06550	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BkAM31D_06555	COG1653	transport
BkAM31D_06560	COG5578	integral membrane protein
BkAM31D_06565	COG0673	inositol 2-dehydrogenase activity
BkAM31D_06570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BkAM31D_06575	COG1609	Transcriptional regulator
BkAM31D_06580	COG0385	Bile acid
BkAM31D_06585	COG2721	sulfolactate sulfo-lyase activity
BkAM31D_06590	COG0246	Mannitol dehydrogenase
BkAM31D_06595	COG0800	Aldolase
BkAM31D_06600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BkAM31D_06605	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_06635	COG3275	phosphorelay sensor kinase activity
BkAM31D_06640	COG3279	Response regulator of the LytR AlgR family
BkAM31D_06645	COG1966	Carbon starvation protein
BkAM31D_06680	COG1191	sigma factor activity
BkAM31D_06690	COG0840	transmembrane signaling receptor activity
BkAM31D_06705	COG0702	epimerase
BkAM31D_06715	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BkAM31D_06720	COG0561	phosphatase activity
BkAM31D_06725	COG2223	nitrite transmembrane transporter activity
BkAM31D_06735	COG1388	LysM domain
BkAM31D_06735	COG3584	3D domain protein
BkAM31D_06750	COG2112	serine threonine protein kinase
BkAM31D_06760	COG4326	sporulation control protein
BkAM31D_06770	COG1122	ATPase activity
BkAM31D_06775	COG4120	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_06785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BkAM31D_06790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BkAM31D_06795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BkAM31D_06805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BkAM31D_06900	COG0546	phosphoglycolate phosphatase activity
BkAM31D_06915	COG2962	Rard protein
BkAM31D_06920	COG2814	Major facilitator Superfamily
BkAM31D_06930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BkAM31D_06955	COG0745	RESPONSE REGULATOR receiver
BkAM31D_06960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BkAM31D_06970	COG1846	Transcriptional regulator
BkAM31D_06975	COG2814	Major facilitator Superfamily
BkAM31D_06990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BkAM31D_07000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BkAM31D_07005	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BkAM31D_07010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_07015	COG0589	response to stress
BkAM31D_07045	COG1619	proteins homologs of microcin C7 resistance protein MccF
BkAM31D_07050	COG1725	Transcriptional regulator
BkAM31D_07055	COG1131	(ABC) transporter
BkAM31D_07080	COG3883	PFAM NLP P60 protein
BkAM31D_07080	COG0791	NLP P60 protein
BkAM31D_07115	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BkAM31D_07120	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BkAM31D_07125	COG1733	regulation of RNA biosynthetic process
BkAM31D_07195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_07215	COG2323	membrane
BkAM31D_07255	COG0697	spore germination
BkAM31D_07270	COG3773	Cell wall hydrolase
BkAM31D_07275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BkAM31D_07280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BkAM31D_07320	COG1063	alcohol dehydrogenase
BkAM31D_07330	COG1595	DNA-templated transcription, initiation
BkAM31D_07345	COG3773	Cell wall hydrolase
BkAM31D_07355	COG1063	alcohol dehydrogenase
BkAM31D_07360	COG5577	PFAM Coat F domain
BkAM31D_07375	COG5577	PFAM Coat F domain
BkAM31D_07430	COG0717	Belongs to the dCTP deaminase family
BkAM31D_07470	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BkAM31D_07475	COG5001	Diguanylate cyclase
BkAM31D_07475	COG3300	MHYT domain
BkAM31D_07490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BkAM31D_07525	COG1309	transcriptional regulator
BkAM31D_07535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BkAM31D_07540	COG0022	dehydrogenase e1 component
BkAM31D_07545	COG0508	dehydrogenase complex catalyzes the overall conversion of
BkAM31D_07550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BkAM31D_07555	COG1024	Enoyl-CoA hydratase
BkAM31D_07560	COG1024	Enoyl-CoA hydratase
BkAM31D_07580	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_07590	COG0410	ABC transporter
BkAM31D_07605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BkAM31D_07620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_07625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_07625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_07635	COG1442	glycosyl transferase family 8
BkAM31D_07640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BkAM31D_07695	COG2112	serine threonine protein kinase
BkAM31D_07710	COG4555	ABC transporter
BkAM31D_07720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BkAM31D_07730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BkAM31D_07735	COG0431	NADPH-dependent FMN reductase
BkAM31D_07735	COG3976	FMN-binding domain protein
BkAM31D_07735	COG1053	succinate dehydrogenase
BkAM31D_07760	COG0583	DNA-binding transcription factor activity
BkAM31D_07765	COG0473	3-isopropylmalate dehydrogenase activity
BkAM31D_07775	COG1132	(ABC) transporter
BkAM31D_07780	COG0435	Glutathione S-transferase
BkAM31D_07790	COG0346	lactoylglutathione lyase activity
BkAM31D_07825	COG0280	phosphate acetyltransferase
BkAM31D_07835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_07845	COG1454	alcohol dehydrogenase
BkAM31D_07855	COG0583	DNA-binding transcription factor activity
BkAM31D_07875	COG0473	3-isopropylmalate dehydrogenase activity
BkAM31D_07890	COG0371	Dehydrogenase
BkAM31D_07905	COG2011	ABC-type metal ion transport system permease component
BkAM31D_07915	COG0561	phosphatase activity
BkAM31D_07920	COG2190	(PTS) system
BkAM31D_07920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_07920	COG1263	PTS System
BkAM31D_07925	COG4753	response regulator
BkAM31D_07925	COG2207	Transcriptional regulator
BkAM31D_07930	COG3250	beta-galactosidase activity
BkAM31D_07955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BkAM31D_07965	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BkAM31D_07970	COG3052	prosthetic group binding
BkAM31D_07995	COG0656	L-ascorbic acid biosynthetic process
BkAM31D_08010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BkAM31D_08010	COG2885	chlorophyll binding
BkAM31D_08030	COG1802	Transcriptional regulator
BkAM31D_08035	COG2084	Dehydrogenase
BkAM31D_08060	COG0191	fructose-bisphosphate aldolase activity
BkAM31D_08080	COG2972	Histidine kinase
BkAM31D_08085	COG2207	Transcriptional regulator
BkAM31D_08085	COG4753	response regulator
BkAM31D_08135	COG1175	transmembrane transport
BkAM31D_08140	COG0395	ABC-type sugar transport system, permease component
BkAM31D_08150	COG1621	beta-fructofuranosidase activity
BkAM31D_08160	COG1131	(ABC) transporter
BkAM31D_08165	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BkAM31D_08170	COG0745	RESPONSE REGULATOR receiver
BkAM31D_08175	COG5002	protein histidine kinase activity
BkAM31D_08180	COG2814	Major facilitator Superfamily
BkAM31D_08190	COG1959	2 iron, 2 sulfur cluster binding
BkAM31D_08200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BkAM31D_08210	COG1737	Transcriptional regulator
BkAM31D_08215	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BkAM31D_08220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_08225	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_08225	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_08235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_08235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_08250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BkAM31D_08255	COG0363	glucosamine-6-phosphate deaminase activity
BkAM31D_08260	COG0842	Transport permease protein
BkAM31D_08265	COG1131	(ABC) transporter
BkAM31D_08270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BkAM31D_08280	COG0346	lactoylglutathione lyase activity
BkAM31D_08285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BkAM31D_08290	COG0400	carboxylic ester hydrolase activity
BkAM31D_08295	COG2259	Doxx family
BkAM31D_08300	COG0655	NAD(P)H dehydrogenase (quinone) activity
BkAM31D_08315	COG4682	membrane
BkAM31D_08325	COG1131	(ABC) transporter
BkAM31D_08360	COG0196	riboflavin kinase activity
BkAM31D_08395	COG3180	Ammonia monooxygenase
BkAM31D_08405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_08410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_08455	COG2204	response regulator
BkAM31D_08460	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_08465	COG2086	electron transfer activity
BkAM31D_08470	COG2086	electron transfer activity
BkAM31D_08475	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BkAM31D_08480	COG0247	lactate metabolic process
BkAM31D_08480	COG2181	nitrate reductase activity
BkAM31D_08485	COG0154	amidase activity
BkAM31D_08490	COG0456	acetyltransferase
BkAM31D_08505	COG1414	Transcriptional regulator
BkAM31D_08510	COG2807	transmembrane transport
BkAM31D_08515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BkAM31D_08525	COG0179	Fumarylacetoacetate (FAA) hydrolase
BkAM31D_08550	COG0659	secondary active sulfate transmembrane transporter activity
BkAM31D_08565	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BkAM31D_08580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BkAM31D_08585	COG0747	negative chemotaxis
BkAM31D_08590	COG2843	Capsule synthesis protein
BkAM31D_08610	COG0477	Major facilitator Superfamily
BkAM31D_08630	COG2843	Capsule synthesis protein
BkAM31D_08640	COG0747	negative chemotaxis
BkAM31D_08655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BkAM31D_08695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_08700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_08715	COG2508	Transcriptional regulator
BkAM31D_08725	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_08730	COG0183	Belongs to the thiolase family
BkAM31D_08735	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_08740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BkAM31D_08745	COG0569	domain protein
BkAM31D_08780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_08800	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BkAM31D_08805	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BkAM31D_08815	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_08820	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_08825	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_08860	COG2072	flavoprotein involved in K transport
BkAM31D_08875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_08895	COG1131	(ABC) transporter
BkAM31D_08905	COG1024	Enoyl-CoA hydratase
BkAM31D_08960	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_08965	COG1042	CoA-binding domain protein
BkAM31D_08965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BkAM31D_08965	COG0045	succinate-CoA ligase (ADP-forming) activity
BkAM31D_08970	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_08975	COG0183	Belongs to the thiolase family
BkAM31D_08980	COG2086	electron transfer activity
BkAM31D_08985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BkAM31D_08990	COG2050	protein possibly involved in aromatic compounds catabolism
BkAM31D_08995	COG3829	transcription factor binding
BkAM31D_08995	COG3290	protein histidine kinase activity
BkAM31D_09005	COG1024	Enoyl-CoA hydratase
BkAM31D_09010	COG0521	Mo-molybdopterin cofactor biosynthetic process
BkAM31D_09025	COG0523	cobalamin synthesis protein
BkAM31D_09060	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BkAM31D_09100	COG0778	Nitroreductase
BkAM31D_09120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BkAM31D_09130	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BkAM31D_09135	COG1492	cobalamin metabolic process
BkAM31D_09145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BkAM31D_09165	COG2755	lipolytic protein G-D-S-L family
BkAM31D_09185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BkAM31D_09190	COG3409	Peptidoglycan-binding domain 1 protein
BkAM31D_09190	COG3773	Cell wall hydrolase
BkAM31D_09215	COG1414	Transcriptional regulator
BkAM31D_09230	COG0733	neurotransmitter:sodium symporter activity
BkAM31D_09250	COG3844	kynureninase activity
BkAM31D_09255	COG1309	transcriptional regulator
BkAM31D_09265	COG0784	Response regulator, receiver
BkAM31D_09270	COG4191	Histidine kinase
BkAM31D_09275	COG1115	amino acid carrier protein
BkAM31D_09290	COG1396	sequence-specific DNA binding
BkAM31D_09295	COG2066	Belongs to the glutaminase family
BkAM31D_09300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_09320	COG2814	Major facilitator Superfamily
BkAM31D_09325	COG2211	Major facilitator Superfamily
BkAM31D_09345	COG0789	Transcriptional regulator
BkAM31D_09355	COG1131	(ABC) transporter
BkAM31D_09375	COG4585	Histidine kinase
BkAM31D_09380	COG2197	response regulator
BkAM31D_09425	COG1404	Belongs to the peptidase S8 family
BkAM31D_09430	COG1404	Belongs to the peptidase S8 family
BkAM31D_09435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BkAM31D_09445	COG2755	lipolytic protein G-D-S-L family
BkAM31D_09450	COG0393	Putative heavy-metal-binding
BkAM31D_09500	COG2972	Histidine kinase
BkAM31D_09505	COG2169	Transcriptional regulator
BkAM31D_09515	COG1621	beta-fructofuranosidase activity
BkAM31D_09525	COG1621	beta-fructofuranosidase activity
BkAM31D_09535	COG1609	Transcriptional regulator
BkAM31D_09540	COG1609	Transcriptional regulator
BkAM31D_09545	COG2182	Extracellular solute-binding protein
BkAM31D_09555	COG0395	ABC-type sugar transport system, permease component
BkAM31D_09560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BkAM31D_09565	COG5578	integral membrane protein
BkAM31D_09585	COG0247	lactate metabolic process
BkAM31D_09585	COG2181	nitrate reductase activity
BkAM31D_09600	COG0515	serine threonine protein kinase
BkAM31D_09600	COG2815	serine threonine protein kinase
BkAM31D_09670	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BkAM31D_09700	COG0827	DNA restriction-modification system
BkAM31D_09715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_09745	COG2433	Pfam Transposase IS66
BkAM31D_09750	COG0210	DNA helicase
BkAM31D_09770	COG2433	Pfam Transposase IS66
BkAM31D_09790	COG2176	DNA-directed DNA polymerase activity
BkAM31D_09795	COG1609	Transcriptional regulator
BkAM31D_09800	COG1879	ABC-type sugar transport system periplasmic component
BkAM31D_09815	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_09820	COG2376	Dihydroxyacetone kinase
BkAM31D_09830	COG4753	response regulator
BkAM31D_09830	COG2207	Transcriptional regulator
BkAM31D_09835	COG2972	Histidine kinase
BkAM31D_09850	COG1175	transmembrane transport
BkAM31D_09855	COG0395	ABC-type sugar transport system, permease component
BkAM31D_09885	COG5564	TIM-barrel signal transduction protein
BkAM31D_09895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_09900	COG0179	Fumarylacetoacetate (FAA) hydrolase
BkAM31D_09930	COG1278	Cold shock
BkAM31D_09955	COG2814	Major facilitator Superfamily
BkAM31D_09960	COG0534	Mate efflux family protein
BkAM31D_09965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BkAM31D_09970	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_09980	COG3284	Transcriptional regulator
BkAM31D_09985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BkAM31D_09990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BkAM31D_09995	COG0022	dehydrogenase e1 component
BkAM31D_10020	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_10040	COG1114	Component of the transport system for branched-chain amino acids
BkAM31D_10045	COG4980	gas vesicle protein
BkAM31D_10050	COG0011	TIGRFAM Protein of
BkAM31D_10080	COG2208	phosphoserine phosphatase activity
BkAM31D_10085	COG0596	Alpha beta hydrolase
BkAM31D_10090	COG0243	molybdopterin cofactor binding
BkAM31D_10100	COG4191	Histidine kinase
BkAM31D_10115	COG0840	transmembrane signaling receptor activity
BkAM31D_10120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BkAM31D_10150	COG0791	NLP P60 protein
BkAM31D_10150	COG1388	LysM domain
BkAM31D_10160	COG0814	amino acid
BkAM31D_10170	COG0697	spore germination
BkAM31D_10185	COG0179	Fumarylacetoacetate (FAA) hydrolase
BkAM31D_10305	COG0583	DNA-binding transcription factor activity
BkAM31D_10350	COG0733	neurotransmitter:sodium symporter activity
BkAM31D_10355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BkAM31D_10380	COG0114	fumarate hydratase activity
BkAM31D_10390	COG2226	methyltransferase
BkAM31D_10395	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BkAM31D_10400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BkAM31D_10400	COG3153	acetyltransferase
BkAM31D_10405	COG0456	acetyltransferase
BkAM31D_10415	COG1733	regulation of RNA biosynthetic process
BkAM31D_10420	COG2514	catechol 2,3-dioxygenase activity
BkAM31D_10425	COG2259	Doxx family
BkAM31D_10430	COG0039	L-malate dehydrogenase activity
BkAM31D_10435	COG1473	amidohydrolase
BkAM31D_10460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_10470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BkAM31D_10470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BkAM31D_10475	COG0307	riboflavin synthase, alpha
BkAM31D_10480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_10480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_10485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BkAM31D_10500	COG0456	acetyltransferase
BkAM31D_10505	COG1547	Domain of unknown function (DUF309)
BkAM31D_10510	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BkAM31D_10515	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BkAM31D_10520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BkAM31D_10530	COG2323	membrane
BkAM31D_10550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_10565	COG2323	membrane
BkAM31D_10570	COG2323	membrane
BkAM31D_10575	COG1686	Belongs to the peptidase S11 family
BkAM31D_10580	COG2715	membrane protein required for spore maturation
BkAM31D_10585	COG0700	Nucleoside recognition
BkAM31D_10600	COG1187	pseudouridine synthase activity
BkAM31D_10605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_10620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BkAM31D_10625	COG0745	RESPONSE REGULATOR receiver
BkAM31D_10640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BkAM31D_10655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BkAM31D_10660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_10665	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BkAM31D_10670	COG1120	ATPase activity
BkAM31D_10675	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BkAM31D_10680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BkAM31D_10685	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BkAM31D_10690	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BkAM31D_10705	COG2096	Adenosyltransferase
BkAM31D_10710	COG2720	vancomycin resistance protein
BkAM31D_10730	COG0739	heme binding
BkAM31D_10745	COG2186	Transcriptional regulator
BkAM31D_10750	COG1141	Ferredoxin
BkAM31D_10755	COG4955	Helix-turn-helix domain
BkAM31D_10760	COG0514	ATP-dependent DNA helicase (RecQ)
BkAM31D_10765	COG1266	CAAX protease self-immunity
BkAM31D_10805	COG1408	metallophosphoesterase
BkAM31D_10815	COG4862	establishment of competence for transformation
BkAM31D_10820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_10825	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_10830	COG0252	asparaginase activity
BkAM31D_10835	COG2339	peptidase activity
BkAM31D_10850	COG0626	cystathionine gamma-synthase activity
BkAM31D_10855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BkAM31D_10855	COG0646	methionine synthase
BkAM31D_10860	COG1410	methionine synthase
BkAM31D_10860	COG0646	methionine synthase
BkAM31D_10865	COG3409	Peptidoglycan-binding domain 1 protein
BkAM31D_10865	COG3773	Cell wall hydrolase
BkAM31D_10885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BkAM31D_10890	COG0204	Acyl-transferase
BkAM31D_10895	COG0539	negative regulation of cytoplasmic translation
BkAM31D_10900	COG1304	FMN binding
BkAM31D_10915	COG1160	GTP binding
BkAM31D_10920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BkAM31D_10925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BkAM31D_10945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BkAM31D_10955	COG0142	geranyltranstransferase activity
BkAM31D_10975	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BkAM31D_10980	COG0142	geranyltranstransferase activity
BkAM31D_10985	COG0105	UTP biosynthetic process
BkAM31D_10990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BkAM31D_11000	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BkAM31D_11005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BkAM31D_11010	COG4401	Chorismate mutase type I
BkAM31D_11015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BkAM31D_11020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BkAM31D_11025	COG0134	indole-3-glycerol-phosphate synthase activity
BkAM31D_11030	COG0135	phosphoribosylanthranilate isomerase activity
BkAM31D_11035	COG0133	tryptophan synthase activity
BkAM31D_11040	COG0159	tryptophan synthase activity
BkAM31D_11045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BkAM31D_11050	COG0287	Prephenate dehydrogenase
BkAM31D_11055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BkAM31D_11065	COG0457	Tetratricopeptide repeat
BkAM31D_11070	COG5582	Belongs to the UPF0302 family
BkAM31D_11080	COG0723	plastoquinol--plastocyanin reductase activity
BkAM31D_11085	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BkAM31D_11090	COG2010	Cytochrome c
BkAM31D_11090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BkAM31D_11095	COG4347	Protein of unknown function (DUF1405)
BkAM31D_11105	COG2738	Putative neutral zinc metallopeptidase
BkAM31D_11110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_11115	COG1694	Mazg nucleotide pyrophosphohydrolase
BkAM31D_11120	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BkAM31D_11125	COG1803	Methylglyoxal synthase
BkAM31D_11130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BkAM31D_11135	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_11170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BkAM31D_11180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BkAM31D_11180	COG1199	ATP-dependent helicase activity
BkAM31D_11200	COG0436	Aminotransferase
BkAM31D_11205	COG0017	Asparaginyl-tRNA synthetase
BkAM31D_11210	COG3935	DnaD domain protein
BkAM31D_11215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BkAM31D_11235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BkAM31D_11235	COG4499	WXG100 protein secretion system (Wss), protein YukC
BkAM31D_11240	COG3331	DNA recombination
BkAM31D_11250	COG0789	Transcriptional regulator
BkAM31D_11260	COG2860	membrane
BkAM31D_11265	COG2860	membrane
BkAM31D_11275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BkAM31D_11285	COG0693	protein deglycase activity
BkAM31D_11290	COG1234	tRNA 3'-trailer cleavage
BkAM31D_11300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_11320	COG1413	lyase activity
BkAM31D_11330	COG3402	PFAM membrane-flanked domain
BkAM31D_11335	COG3428	Bacterial PH domain
BkAM31D_11375	COG0493	'glutamate synthase
BkAM31D_11385	COG2124	cytochrome p450
BkAM31D_11430	COG1473	amidohydrolase
BkAM31D_11435	COG0460	homoserine dehydrogenase
BkAM31D_11440	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_11445	COG0006	proline dipeptidase activity
BkAM31D_11450	COG0697	spore germination
BkAM31D_11455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BkAM31D_11505	COG1278	Cold shock
BkAM31D_11510	COG0768	penicillin binding
BkAM31D_11515	COG0768	penicillin binding
BkAM31D_11530	COG1205	dead DEAH box helicase
BkAM31D_11530	COG1111	helicase
BkAM31D_11535	COG3359	exonuclease
BkAM31D_11545	COG4474	Belongs to the UPF0398 family
BkAM31D_11550	COG3599	regulation of cell shape
BkAM31D_11555	COG0328	RNA-DNA hybrid ribonuclease activity
BkAM31D_11570	COG0116	Belongs to the methyltransferase superfamily
BkAM31D_11575	COG2826	transposase and inactivated derivatives, IS30 family
BkAM31D_11625	COG1131	(ABC) transporter
BkAM31D_11630	COG5522	Integral membrane protein (intg_mem_TP0381)
BkAM31D_11645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BkAM31D_11650	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BkAM31D_11665	COG0604	alcohol dehydrogenase
BkAM31D_11675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BkAM31D_11680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BkAM31D_11685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BkAM31D_11690	COG1116	anion transmembrane transporter activity
BkAM31D_11695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BkAM31D_11700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BkAM31D_11705	COG0671	phosphoesterase, PA-phosphatase related
BkAM31D_11725	COG0583	DNA-binding transcription factor activity
BkAM31D_11730	COG3829	transcription factor binding
BkAM31D_11730	COG3290	protein histidine kinase activity
BkAM31D_11740	COG2610	gluconate transmembrane transporter activity
BkAM31D_11745	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_11750	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_11755	COG3118	belongs to the thioredoxin family
BkAM31D_11770	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_11770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_11785	COG4325	translation initiation factor activity
BkAM31D_11790	COG1832	CoA-binding protein
BkAM31D_11795	COG0187	DNA topoisomerase II activity
BkAM31D_11800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BkAM31D_11805	COG1988	membrane-bound metal-dependent
BkAM31D_11810	COG0205	6-phosphofructokinase activity
BkAM31D_11835	COG2027	D-alanyl-D-alanine carboxypeptidase
BkAM31D_11850	COG2720	vancomycin resistance protein
BkAM31D_11875	COG0431	NADPH-dependent FMN reductase
BkAM31D_11880	COG1846	Transcriptional regulator
BkAM31D_11910	COG1063	alcohol dehydrogenase
BkAM31D_11915	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BkAM31D_11955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BkAM31D_11965	COG2223	nitrite transmembrane transporter activity
BkAM31D_11980	COG2146	nitrite reductase [NAD(P)H] activity
BkAM31D_11990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BkAM31D_11995	COG1151	hydroxylamine reductase activity
BkAM31D_12000	COG2860	membrane
BkAM31D_12005	COG3835	regulator
BkAM31D_12020	COG1473	amidohydrolase
BkAM31D_12045	COG5002	protein histidine kinase activity
BkAM31D_12060	COG2357	RelA SpoT domain protein
BkAM31D_12070	COG0326	Molecular chaperone. Has ATPase activity
BkAM31D_12090	COG2433	Pfam Transposase IS66
BkAM31D_12095	COG3594	Acyltransferase
BkAM31D_12115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BkAM31D_12120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BkAM31D_12130	COG0640	Transcriptional regulator
BkAM31D_12135	COG0024	Methionine aminopeptidase
BkAM31D_12145	COG0489	protein tyrosine kinase activity
BkAM31D_12150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BkAM31D_12175	COG0437	4 iron, 4 sulfur cluster binding
BkAM31D_12190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BkAM31D_12200	COG0436	Aminotransferase
BkAM31D_12220	COG1278	Cold shock
BkAM31D_12245	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BkAM31D_12250	COG2323	membrane
BkAM31D_12255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_12260	COG0583	DNA-binding transcription factor activity
BkAM31D_12265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BkAM31D_12270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BkAM31D_12275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_12280	COG1454	alcohol dehydrogenase
BkAM31D_12290	COG3852	Histidine kinase
BkAM31D_12295	COG4974	Belongs to the 'phage' integrase family
BkAM31D_12315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BkAM31D_12335	COG0542	response to heat
BkAM31D_12365	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BkAM31D_12385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BkAM31D_12405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BkAM31D_12410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BkAM31D_12420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BkAM31D_12430	COG1509	lysine 2,3-aminomutase activity
BkAM31D_12435	COG0456	acetyltransferase
BkAM31D_12440	COG3829	transcription factor binding
BkAM31D_12445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BkAM31D_12450	COG1388	LysM domain
BkAM31D_12450	COG3858	chitin binding
BkAM31D_12460	COG0778	Nitroreductase
BkAM31D_12485	COG0514	ATP-dependent DNA helicase (RecQ)
BkAM31D_12490	COG0704	Plays a role in the regulation of phosphate uptake
BkAM31D_12500	COG3852	Histidine kinase
BkAM31D_12510	COG1744	ABC transporter substrate-binding protein PnrA-like
BkAM31D_12530	COG3559	Exporter of polyketide antibiotics
BkAM31D_12535	COG1131	(ABC) transporter
BkAM31D_12550	COG1278	Cold shock
BkAM31D_12570	COG0596	Alpha beta hydrolase
BkAM31D_12580	COG4536	flavin adenine dinucleotide binding
BkAM31D_12585	COG1959	2 iron, 2 sulfur cluster binding
BkAM31D_12600	COG2271	Major facilitator Superfamily
BkAM31D_12665	COG4325	translation initiation factor activity
BkAM31D_12675	COG1937	Protein conserved in bacteria
BkAM31D_12680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BkAM31D_12705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BkAM31D_12720	COG1119	ATPase activity
BkAM31D_12750	COG3011	Protein conserved in bacteria
BkAM31D_12755	COG2258	MOSC domain
BkAM31D_12760	COG0708	Exodeoxyribonuclease III
BkAM31D_12765	COG1834	amidinotransferase
BkAM31D_12790	COG1113	amino acid transport
BkAM31D_12795	COG1280	lysine exporter protein (LysE YggA)
BkAM31D_12810	COG1164	Oligoendopeptidase f
BkAM31D_12825	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_12840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BkAM31D_12895	COG0730	response to heat
BkAM31D_12900	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_12905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_12905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_12910	COG2210	Belongs to the sulfur carrier protein TusA family
BkAM31D_12920	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_12920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_12925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_12935	COG2210	Belongs to the sulfur carrier protein TusA family
BkAM31D_12940	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_12945	COG1937	Protein conserved in bacteria
BkAM31D_12975	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_12980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_12980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_12985	COG2210	Belongs to the sulfur carrier protein TusA family
BkAM31D_12990	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_12990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_13005	COG1183	phosphatidylcholine synthase activity
BkAM31D_13020	COG0517	IMP dehydrogenase activity
BkAM31D_13030	COG2223	nitrite transmembrane transporter activity
BkAM31D_13035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BkAM31D_13040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BkAM31D_13045	COG2226	methyltransferase
BkAM31D_13055	COG1285	pathogenesis
BkAM31D_13060	COG2340	Cysteine-rich secretory protein family
BkAM31D_13065	COG3973	AAA domain
BkAM31D_13075	COG0400	carboxylic ester hydrolase activity
BkAM31D_13100	COG1199	ATP-dependent helicase activity
BkAM31D_13120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BkAM31D_13130	COG0300	oxidoreductase activity
BkAM31D_13140	COG0697	spore germination
BkAM31D_13145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BkAM31D_13170	COG2105	PFAM AIG2 family protein
BkAM31D_13175	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_13215	COG4895	conserved protein (DUF2196)
BkAM31D_13225	COG2217	Heavy metal translocating P-type atpase
BkAM31D_13230	COG2608	mercury ion transmembrane transporter activity
BkAM31D_13235	COG1937	Protein conserved in bacteria
BkAM31D_13250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BkAM31D_13255	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BkAM31D_13270	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BkAM31D_13295	COG1307	EDD domain protein, DegV family
BkAM31D_13300	COG0514	ATP-dependent DNA helicase (RecQ)
BkAM31D_13310	COG0488	(ABC) transporter
BkAM31D_13320	COG0697	spore germination
BkAM31D_13325	COG0586	Pfam SNARE associated Golgi protein
BkAM31D_13335	COG0508	dehydrogenase complex catalyzes the overall conversion of
BkAM31D_13340	COG0567	Dehydrogenase, E1 component
BkAM31D_13375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BkAM31D_13380	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_13385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BkAM31D_13390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BkAM31D_13395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BkAM31D_13405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BkAM31D_13565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_13680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BkAM31D_13690	COG0720	synthase
BkAM31D_13695	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BkAM31D_13700	COG2309	aminopeptidase activity
BkAM31D_13710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BkAM31D_13720	COG4841	protein insertion into membrane
BkAM31D_13730	COG0835	chemotaxis
BkAM31D_13730	COG0784	Response regulator, receiver
BkAM31D_13770	COG2200	EAL domain
BkAM31D_13775	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BkAM31D_13780	COG0328	RNA-DNA hybrid ribonuclease activity
BkAM31D_13785	COG1666	GTP binding
BkAM31D_13790	COG0613	PHP domain protein
BkAM31D_13800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BkAM31D_13815	COG0824	Thioesterase
BkAM31D_13820	COG0464	growth
BkAM31D_13825	COG0697	spore germination
BkAM31D_13840	COG0398	Pfam SNARE associated Golgi protein
BkAM31D_13860	COG2323	membrane
BkAM31D_13870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BkAM31D_13890	COG1607	acyl-coa hydrolase
BkAM31D_13905	COG0709	Synthesizes selenophosphate from selenide and ATP
BkAM31D_13915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BkAM31D_13945	COG1228	amidohydrolase
BkAM31D_13950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BkAM31D_13955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BkAM31D_13960	COG2986	histidine ammonia-lyase
BkAM31D_14015	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_14025	COG0385	Bile acid
BkAM31D_14050	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_14065	COG0601	transmembrane transport
BkAM31D_14090	COG0477	Major facilitator Superfamily
BkAM31D_14105	COG2340	Cysteine-rich secretory protein family
BkAM31D_14110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_14135	COG0626	cystathionine gamma-synthase activity
BkAM31D_14160	COG2267	carboxylic ester hydrolase activity
BkAM31D_14165	COG0671	phosphoesterase, PA-phosphatase related
BkAM31D_14205	COG4846	Membrane protein involved in cytochrome C biogenesis
BkAM31D_14210	COG1132	(ABC) transporter
BkAM31D_14215	COG1132	(ABC) transporter
BkAM31D_14230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BkAM31D_14235	COG4224	UPF0291 protein
BkAM31D_14240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_14250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BkAM31D_14265	COG0174	glutamine synthetase
BkAM31D_14270	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BkAM31D_14300	COG1923	regulation of RNA biosynthetic process
BkAM31D_14305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BkAM31D_14310	COG2521	methyltransferase
BkAM31D_14310	COG2136	Putative SAM-dependent methyltransferase
BkAM31D_14315	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BkAM31D_14320	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BkAM31D_14330	COG4550	Control of competence regulator ComK, YlbF/YmcA
BkAM31D_14335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BkAM31D_14340	COG1013	pyruvate-flavodoxin oxidoreductase activity
BkAM31D_14355	COG0697	spore germination
BkAM31D_14375	COG2359	stage V sporulation protein S
BkAM31D_14380	COG1692	metallophosphoesterase
BkAM31D_14385	COG1418	mRNA catabolic process
BkAM31D_14400	COG0497	DNA recombination
BkAM31D_14410	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BkAM31D_14415	COG0513	Belongs to the DEAD box helicase family
BkAM31D_14420	COG1058	Belongs to the CinA family
BkAM31D_14420	COG1546	Belongs to the CinA family
BkAM31D_14425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BkAM31D_14430	COG1426	Protein conserved in bacteria
BkAM31D_14445	COG0300	oxidoreductase activity
BkAM31D_14450	COG0612	Peptidase, M16
BkAM31D_14455	COG0612	Peptidase, M16
BkAM31D_14460	COG2188	Transcriptional regulator
BkAM31D_14465	COG1674	ftsk spoiiie
BkAM31D_14475	COG0740	serine-type endopeptidase activity
BkAM31D_14490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BkAM31D_14495	COG0527	aspartate kinase activity
BkAM31D_14500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BkAM31D_14505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BkAM31D_14510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BkAM31D_14515	COG1873	PFAM PRC-barrel domain
BkAM31D_14520	COG0612	Peptidase, M16
BkAM31D_14535	COG1185	polyribonucleotide nucleotidyltransferase activity
BkAM31D_14540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BkAM31D_14545	COG0196	riboflavin kinase activity
BkAM31D_14550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BkAM31D_14555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BkAM31D_14565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BkAM31D_14570	COG1358	cellular component organization or biogenesis
BkAM31D_14575	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BkAM31D_14580	COG0195	Participates in both transcription termination and antitermination
BkAM31D_14585	COG0779	Required for maturation of 30S ribosomal subunits
BkAM31D_14600	COG0442	prolyl-tRNA aminoacylation
BkAM31D_14605	COG0750	zinc metalloprotease
BkAM31D_14610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BkAM31D_14615	COG4589	Belongs to the CDS family
BkAM31D_14620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BkAM31D_14625	COG0233	cytoplasmic translational termination
BkAM31D_14630	COG0528	UMP kinase activity
BkAM31D_14635	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BkAM31D_14640	COG0052	Belongs to the universal ribosomal protein uS2 family
BkAM31D_14650	COG1191	sigma factor activity
BkAM31D_14655	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BkAM31D_14660	COG1776	CheC inhibitor of MCP methylation
BkAM31D_14665	COG2201	protein-glutamate methylesterase activity
BkAM31D_14670	COG0455	bacterial-type flagellum organization
BkAM31D_14675	COG1419	protein localization to endoplasmic reticulum
BkAM31D_14680	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BkAM31D_14685	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BkAM31D_14690	COG1684	flagellar biosynthetic protein fliR
BkAM31D_14695	COG1987	bacterial-type flagellum assembly
BkAM31D_14700	COG1338	Plays a role in the flagellum-specific transport system
BkAM31D_14705	COG3190	flagellar
BkAM31D_14710	COG1776	CheC inhibitor of MCP methylation
BkAM31D_14710	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BkAM31D_14715	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BkAM31D_14725	COG1582	Flagellar protein (FlbD)
BkAM31D_14730	COG4786	Flagellar basal body rod
BkAM31D_14740	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BkAM31D_14755	COG2882	bacterial-type flagellum organization
BkAM31D_14760	COG1157	protein secretion by the type III secretion system
BkAM31D_14770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BkAM31D_14775	COG1766	The M ring may be actively involved in energy transduction
BkAM31D_14780	COG1677	Flagellar hook-basal body complex protein FliE
BkAM31D_14785	COG1558	bacterial-type flagellum-dependent cell motility
BkAM31D_14790	COG1815	bacterial-type flagellum-dependent cell motility
BkAM31D_14795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BkAM31D_14800	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BkAM31D_14805	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BkAM31D_14810	COG4974	Belongs to the 'phage' integrase family
BkAM31D_14815	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BkAM31D_14820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BkAM31D_14825	COG0758	DNA mediated transformation
BkAM31D_14830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BkAM31D_14835	COG0045	succinate-CoA ligase (ADP-forming) activity
BkAM31D_14845	COG2257	FlhB HrpN YscU SpaS Family
BkAM31D_14855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BkAM31D_14870	COG0335	large ribosomal subunit rRNA binding
BkAM31D_14880	COG0336	Belongs to the RNA methyltransferase TrmD family
BkAM31D_14885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BkAM31D_14895	COG1837	Belongs to the UPF0109 family
BkAM31D_14900	COG0228	four-way junction DNA binding
BkAM31D_14905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BkAM31D_14910	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BkAM31D_14915	COG0552	protein localization to endoplasmic reticulum
BkAM31D_14920	COG1196	nuclear chromosome segregation
BkAM31D_14925	COG4840	Belongs to the UPF0435 family
BkAM31D_14930	COG0571	ribonuclease III activity
BkAM31D_14935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BkAM31D_14940	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_14945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BkAM31D_14950	COG0416	fatty acid biosynthetic process
BkAM31D_14955	COG1349	DNA-binding transcription factor activity
BkAM31D_14960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BkAM31D_14965	COG1760	l-serine dehydratase
BkAM31D_14970	COG1760	l-serine dehydratase
BkAM31D_14975	COG1307	EDD domain protein, DegV family
BkAM31D_14980	COG1461	Dihydroxyacetone kinase
BkAM31D_14985	COG1302	Protein conserved in bacteria
BkAM31D_14990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BkAM31D_14995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BkAM31D_15000	COG1162	GTPase activity
BkAM31D_15005	COG2815	serine threonine protein kinase
BkAM31D_15005	COG0515	serine threonine protein kinase
BkAM31D_15010	COG0631	protein serine/threonine phosphatase activity
BkAM31D_15015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BkAM31D_15020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BkAM31D_15020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BkAM31D_15025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BkAM31D_15030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BkAM31D_15035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BkAM31D_15040	COG1758	RNA polymerase activity
BkAM31D_15045	COG0194	GDP metabolic process
BkAM31D_15050	COG2052	Domain of unknown function (DUF370)
BkAM31D_15055	COG1561	YicC-like family, N-terminal region
BkAM31D_15075	COG2226	methyltransferase
BkAM31D_15080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BkAM31D_15085	COG0284	orotidine-5'-phosphate decarboxylase activity
BkAM31D_15090	COG0167	dihydroorotate dehydrogenase activity
BkAM31D_15095	COG0543	2 iron, 2 sulfur cluster binding
BkAM31D_15100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BkAM31D_15105	COG0505	Belongs to the CarA family
BkAM31D_15110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BkAM31D_15115	COG0540	Belongs to the ATCase OTCase family
BkAM31D_15120	COG2233	PERMEase
BkAM31D_15130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BkAM31D_15140	COG0564	pseudouridine synthase activity
BkAM31D_15145	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BkAM31D_15150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BkAM31D_15155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BkAM31D_15165	COG3599	regulation of cell shape
BkAM31D_15170	COG2302	S4 RNA-binding domain
BkAM31D_15175	COG0762	integral membrane protein
BkAM31D_15180	COG1799	cell septum assembly
BkAM31D_15185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BkAM31D_15195	COG1873	PFAM PRC-barrel domain
BkAM31D_15200	COG1191	sigma factor activity
BkAM31D_15205	COG1191	sigma factor activity
BkAM31D_15215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BkAM31D_15220	COG0849	cell division
BkAM31D_15225	COG3856	small basic protein
BkAM31D_15230	COG3879	Bacterial protein of unknown function (DUF881)
BkAM31D_15235	COG3879	Bacterial protein of unknown function (DUF881)
BkAM31D_15240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BkAM31D_15245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BkAM31D_15250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BkAM31D_15255	COG0772	Belongs to the SEDS family
BkAM31D_15260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BkAM31D_15265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BkAM31D_15270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BkAM31D_15275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BkAM31D_15280	COG0768	penicillin binding
BkAM31D_15295	COG0275	rRNA processing
BkAM31D_15300	COG2001	Belongs to the MraZ family
BkAM31D_15305	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BkAM31D_15315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BkAM31D_15320	COG0454	-acetyltransferase
BkAM31D_15330	COG1024	Enoyl-CoA hydratase
BkAM31D_15335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BkAM31D_15345	COG1323	Belongs to the UPF0348 family
BkAM31D_15350	COG3480	Lon protease (S16) C-terminal proteolytic domain
BkAM31D_15355	COG1752	Esterase of the alpha-beta hydrolase superfamily
BkAM31D_15360	COG3314	Sporulation integral membrane protein YlbJ
BkAM31D_15365	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BkAM31D_15370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BkAM31D_15375	COG0742	ribosomal rna small subunit methyltransferase
BkAM31D_15400	COG4471	UPF0298 protein
BkAM31D_15410	COG3679	Belongs to the UPF0342 family
BkAM31D_15415	COG4294	response to UV
BkAM31D_15445	COG2340	Cysteine-rich secretory protein family
BkAM31D_15470	COG5002	protein histidine kinase activity
BkAM31D_15475	COG0745	RESPONSE REGULATOR receiver
BkAM31D_15520	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BkAM31D_15525	COG4838	Belongs to the UPF0358 family
BkAM31D_15530	COG2066	Belongs to the glutaminase family
BkAM31D_15535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BkAM31D_15540	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BkAM31D_15550	COG4896	Protein conserved in bacteria
BkAM31D_15575	COG0483	inositol monophosphate 1-phosphatase activity
BkAM31D_15585	COG4493	Belongs to the UPF0637 family
BkAM31D_15590	COG4476	Belongs to the UPF0223 family
BkAM31D_15605	COG1982	Orn Lys Arg decarboxylase major
BkAM31D_15630	COG4129	membrane
BkAM31D_15635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_15655	COG0508	dehydrogenase complex catalyzes the overall conversion of
BkAM31D_15660	COG0022	dehydrogenase e1 component
BkAM31D_15695	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BkAM31D_15710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_15715	COG0450	alkyl hydroperoxide reductase
BkAM31D_15720	COG0668	transmembrane transport
BkAM31D_15730	COG1473	amidohydrolase
BkAM31D_15735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BkAM31D_15740	COG2171	N-acyltransferase activity
BkAM31D_15745	COG0679	Auxin Efflux Carrier
BkAM31D_15750	COG2224	Isocitrate lyase
BkAM31D_15760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_15765	COG0668	transmembrane transport
BkAM31D_15785	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BkAM31D_15790	COG3285	dna ligase
BkAM31D_15790	COG1793	dna ligase
BkAM31D_15795	COG0778	Nitroreductase
BkAM31D_15800	COG3192	ethanolamine utilization protein
BkAM31D_15810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BkAM31D_15815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BkAM31D_15820	COG2186	Transcriptional regulator
BkAM31D_15825	COG0710	3-dehydroquinate dehydratase activity
BkAM31D_15830	COG0028	Belongs to the TPP enzyme family
BkAM31D_15840	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_15845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BkAM31D_15870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_15875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_15895	COG2508	Transcriptional regulator
BkAM31D_15900	COG3842	ATPase activity
BkAM31D_15905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BkAM31D_15910	COG1414	Transcriptional regulator
BkAM31D_15920	COG0673	inositol 2-dehydrogenase activity
BkAM31D_15925	COG0673	inositol 2-dehydrogenase activity
BkAM31D_15935	COG1609	Transcriptional regulator
BkAM31D_15940	COG2207	Transcriptional regulator
BkAM31D_15940	COG4753	response regulator
BkAM31D_15945	COG2972	Histidine kinase
BkAM31D_15975	COG0366	Alpha amylase catalytic
BkAM31D_15980	COG1609	Transcriptional regulator
BkAM31D_15985	COG3833	ABC-type maltose transport systems, permease component
BkAM31D_15990	COG1175	transmembrane transport
BkAM31D_15995	COG2182	Extracellular solute-binding protein
BkAM31D_16000	COG0534	Mate efflux family protein
BkAM31D_16005	COG1404	Belongs to the peptidase S8 family
BkAM31D_16030	COG2340	Cysteine-rich secretory protein family
BkAM31D_16040	COG1525	nuclease
BkAM31D_16060	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_16065	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_16095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BkAM31D_16100	COG0205	6-phosphofructokinase activity
BkAM31D_16115	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BkAM31D_16120	COG1691	(AIR) carboxylase
BkAM31D_16125	COG1070	Carbohydrate kinase
BkAM31D_16130	COG1606	tRNA processing
BkAM31D_16135	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_16145	COG1904	glucuronate isomerase
BkAM31D_16155	COG0582	viral genome integration into host DNA
BkAM31D_16165	COG5002	protein histidine kinase activity
BkAM31D_16170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BkAM31D_16175	COG2205	protein histidine kinase activity
BkAM31D_16175	COG0784	Response regulator, receiver
BkAM31D_16185	COG1082	Xylose isomerase domain protein TIM barrel
BkAM31D_16190	COG0523	cobalamin synthesis protein
BkAM31D_16195	COG5577	PFAM Coat F domain
BkAM31D_16210	COG5577	PFAM Coat F domain
BkAM31D_16215	COG1063	alcohol dehydrogenase
BkAM31D_16225	COG3773	Cell wall hydrolase
BkAM31D_16235	COG1082	Xylose isomerase domain protein TIM barrel
BkAM31D_16240	COG0673	inositol 2-dehydrogenase activity
BkAM31D_16245	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_16250	COG1129	ABC transporter
BkAM31D_16255	COG0673	inositol 2-dehydrogenase activity
BkAM31D_16270	COG1609	Transcriptional regulator
BkAM31D_16280	COG3279	Response regulator of the LytR AlgR family
BkAM31D_16285	COG0784	Response regulator, receiver
BkAM31D_16285	COG2205	protein histidine kinase activity
BkAM31D_16305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BkAM31D_16310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BkAM31D_16315	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BkAM31D_16320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BkAM31D_16325	COG0300	oxidoreductase activity
BkAM31D_16330	COG0656	L-ascorbic acid biosynthetic process
BkAM31D_16335	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_16340	COG1733	regulation of RNA biosynthetic process
BkAM31D_16345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BkAM31D_16350	COG0482	sulfurtransferase activity
BkAM31D_16355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BkAM31D_16390	COG3773	Cell wall hydrolase
BkAM31D_16410	COG0183	Belongs to the thiolase family
BkAM31D_16415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BkAM31D_16420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BkAM31D_16435	COG0542	response to heat
BkAM31D_16440	COG1253	flavin adenine dinucleotide binding
BkAM31D_16455	COG1253	flavin adenine dinucleotide binding
BkAM31D_16475	COG5002	protein histidine kinase activity
BkAM31D_16505	COG0582	viral genome integration into host DNA
BkAM31D_16545	COG4372	Transposase
BkAM31D_16570	COG0704	Plays a role in the regulation of phosphate uptake
BkAM31D_16595	COG1320	monovalent cation:proton antiporter activity
BkAM31D_16600	COG2212	antiporter activity
BkAM31D_16605	COG1863	multisubunit Na H antiporter MnhE subunit
BkAM31D_16610	COG0651	ATP synthesis coupled electron transport
BkAM31D_16640	COG3263	regulation of cellular component size
BkAM31D_16645	COG0582	viral genome integration into host DNA
BkAM31D_16660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_16695	COG4974	Belongs to the 'phage' integrase family
BkAM31D_16705	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_16740	COG0084	hydrolase, TatD family'
BkAM31D_16780	COG0508	dehydrogenase complex catalyzes the overall conversion of
BkAM31D_16785	COG0022	dehydrogenase e1 component
BkAM31D_16790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BkAM31D_16795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BkAM31D_16805	COG3829	transcription factor binding
BkAM31D_16805	COG3290	protein histidine kinase activity
BkAM31D_16820	COG0463	Glycosyl transferase, family 2
BkAM31D_16830	COG0745	RESPONSE REGULATOR receiver
BkAM31D_16835	COG0750	zinc metalloprotease
BkAM31D_16840	COG0497	DNA recombination
BkAM31D_16845	COG1438	arginine binding
BkAM31D_16850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BkAM31D_16855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BkAM31D_16875	COG1722	exodeoxyribonuclease VII activity
BkAM31D_16880	COG1570	exodeoxyribonuclease VII activity
BkAM31D_16885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BkAM31D_16890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BkAM31D_16895	COG1302	Protein conserved in bacteria
BkAM31D_16900	COG0439	Biotin carboxylase
BkAM31D_16905	COG0511	ligase activity, forming carbon-carbon bonds
BkAM31D_16950	COG3854	ATPases associated with a variety of cellular activities
BkAM31D_16960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BkAM31D_16965	COG0006	proline dipeptidase activity
BkAM31D_16980	COG1752	Esterase of the alpha-beta hydrolase superfamily
BkAM31D_16985	COG1321	iron dependent repressor
BkAM31D_16990	COG1533	DNA photolyase activity
BkAM31D_16995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BkAM31D_17015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_17020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BkAM31D_17025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BkAM31D_17030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BkAM31D_17040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_17055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_17095	COG4537	Required for transformation and DNA binding
BkAM31D_17100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BkAM31D_17200	COG1459	type II secretion system
BkAM31D_17210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BkAM31D_17225	COG1403	HNH endonuclease
BkAM31D_17235	COG0210	DNA helicase
BkAM31D_17240	COG1418	mRNA catabolic process
BkAM31D_17265	COG0475	glutathione-regulated potassium exporter activity
BkAM31D_17265	COG0589	response to stress
BkAM31D_17270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BkAM31D_17280	COG0564	pseudouridine synthase activity
BkAM31D_17285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BkAM31D_17290	COG2357	RelA SpoT domain protein
BkAM31D_17305	COG0741	lytic transglycosylase activity
BkAM31D_17310	COG2346	COG2346, Truncated hemoglobins
BkAM31D_17320	COG1164	Oligoendopeptidase f
BkAM31D_17325	COG4469	Competence protein
BkAM31D_17340	COG0861	Integral membrane protein TerC family
BkAM31D_17345	COG1393	Belongs to the ArsC family
BkAM31D_17355	COG0456	acetyltransferase
BkAM31D_17365	COG0166	Belongs to the GPI family
BkAM31D_17370	COG1272	protein, Hemolysin III
BkAM31D_17375	COG1418	mRNA catabolic process
BkAM31D_17410	COG1063	alcohol dehydrogenase
BkAM31D_17455	COG5504	Zn-dependent protease
BkAM31D_17475	COG1072	(Pantothenic acid kinase))
BkAM31D_17480	COG3773	Cell wall hydrolase
BkAM31D_17495	COG0617	tRNA 3'-terminal CCA addition
BkAM31D_17500	COG0427	acetyl-CoA hydrolase
BkAM31D_17505	COG1316	TRANSCRIPTIONal
BkAM31D_17510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BkAM31D_17515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_17535	COG1744	ABC transporter substrate-binding protein PnrA-like
BkAM31D_17540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BkAM31D_17550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BkAM31D_17555	COG2267	carboxylic ester hydrolase activity
BkAM31D_17565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BkAM31D_17570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BkAM31D_17575	COG0505	Belongs to the CarA family
BkAM31D_17590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BkAM31D_17595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BkAM31D_17600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BkAM31D_17615	COG1999	signal sequence binding
BkAM31D_17620	COG3336	cytochrome c oxidase
BkAM31D_17625	COG0561	phosphatase activity
BkAM31D_17650	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BkAM31D_17665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_17680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_17685	COG1073	alpha beta
BkAM31D_17700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_17700	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_17705	COG0628	permease
BkAM31D_17725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BkAM31D_17725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BkAM31D_17735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BkAM31D_17740	COG1309	transcriptional regulator
BkAM31D_17755	COG0569	domain protein
BkAM31D_17760	COG2201	protein-glutamate methylesterase activity
BkAM31D_17765	COG0835	chemotaxis
BkAM31D_17770	COG0643	Histidine kinase
BkAM31D_17770	COG2198	Histidine kinase
BkAM31D_17775	COG5001	Diguanylate cyclase
BkAM31D_17775	COG3300	MHYT domain
BkAM31D_17780	COG1074	ATP-dependent DNA helicase activity
BkAM31D_17785	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BkAM31D_17790	COG2153	protein acetylation
BkAM31D_17795	COG2368	4-hydroxyphenylacetate
BkAM31D_17810	COG0805	protein transport
BkAM31D_17815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BkAM31D_17835	COG0704	Plays a role in the regulation of phosphate uptake
BkAM31D_17840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BkAM31D_17845	COG0581	inorganic phosphate transmembrane transporter activity
BkAM31D_17850	COG0573	inorganic phosphate transmembrane transporter activity
BkAM31D_17855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BkAM31D_17865	COG4191	Histidine kinase
BkAM31D_17875	COG1668	transmembrane transport
BkAM31D_17880	COG4152	abc transporter atp-binding protein
BkAM31D_17895	COG0697	spore germination
BkAM31D_17905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BkAM31D_17925	COG0659	secondary active sulfate transmembrane transporter activity
BkAM31D_17930	COG0346	lactoylglutathione lyase activity
BkAM31D_17950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BkAM31D_17955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BkAM31D_17960	COG0640	Transcriptional regulator
BkAM31D_17965	COG1234	tRNA 3'-trailer cleavage
BkAM31D_17975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BkAM31D_17980	COG2868	ribosomal protein
BkAM31D_17985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BkAM31D_17995	COG1530	ribonuclease E activity
BkAM31D_18000	COG1994	Peptidase M50
BkAM31D_18005	COG0739	heme binding
BkAM31D_18010	COG0667	Aldo Keto reductase
BkAM31D_18015	COG0521	Mo-molybdopterin cofactor biosynthetic process
BkAM31D_18020	COG2894	cell division
BkAM31D_18025	COG0850	regulation of cytokinetic process
BkAM31D_18040	COG1077	Cell shape determining protein MreB Mrl
BkAM31D_18045	COG2003	Belongs to the UPF0758 family
BkAM31D_18050	COG0424	maF-like protein
BkAM31D_18070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BkAM31D_18110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BkAM31D_18125	COG0285	dihydrofolate synthase activity
BkAM31D_18140	COG1595	DNA-templated transcription, initiation
BkAM31D_18145	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BkAM31D_18180	COG1388	LysM domain
BkAM31D_18185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BkAM31D_18190	COG0113	porphobilinogen synthase activity
BkAM31D_18195	COG1587	Uroporphyrinogen-III synthase
BkAM31D_18200	COG0181	hydroxymethylbilane synthase activity
BkAM31D_18205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BkAM31D_18210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BkAM31D_18220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BkAM31D_18235	COG0470	DNA polymerase III
BkAM31D_18235	COG1067	ATP-dependent peptidase activity
BkAM31D_18240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BkAM31D_18245	COG0544	peptidyl-prolyl cis-trans isomerase activity
BkAM31D_18255	COG1477	protein flavinylation
BkAM31D_18255	COG0457	Tetratricopeptide repeat
BkAM31D_18260	COG0066	3-isopropylmalate dehydratase activity
BkAM31D_18265	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BkAM31D_18270	COG0473	3-isopropylmalate dehydrogenase activity
BkAM31D_18275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BkAM31D_18280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BkAM31D_18285	COG0440	acetolactate synthase activity
BkAM31D_18290	COG0028	Belongs to the TPP enzyme family
BkAM31D_18300	COG0129	dihydroxy-acid dehydratase activity
BkAM31D_18305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BkAM31D_18325	COG0622	Phosphoesterase
BkAM31D_18330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BkAM31D_18335	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BkAM31D_18340	COG5401	PFAM Sporulation and spore germination
BkAM31D_18350	COG1846	Transcriptional regulator
BkAM31D_18355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BkAM31D_18360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BkAM31D_18365	COG2197	response regulator
BkAM31D_18375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BkAM31D_18380	COG1053	succinate dehydrogenase
BkAM31D_18385	COG2009	succinate dehydrogenase
BkAM31D_18390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BkAM31D_18395	COG1719	4-vinyl reductase, 4VR
BkAM31D_18410	COG0322	excinuclease ABC activity
BkAM31D_18415	COG3118	belongs to the thioredoxin family
BkAM31D_18420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BkAM31D_18425	COG2086	electron transfer activity
BkAM31D_18430	COG1024	Enoyl-CoA hydratase
BkAM31D_18435	COG1309	transcriptional regulator
BkAM31D_18440	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_18450	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_18455	COG3766	membrane
BkAM31D_18460	COG1193	negative regulation of DNA recombination
BkAM31D_18475	COG1286	toxin biosynthetic process
BkAM31D_18480	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BkAM31D_18485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BkAM31D_18485	COG0072	phenylalanine-tRNA ligase activity
BkAM31D_18490	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BkAM31D_18500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BkAM31D_18510	COG1363	Peptidase, m42
BkAM31D_18535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BkAM31D_18540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BkAM31D_18545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BkAM31D_18555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BkAM31D_18560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BkAM31D_18575	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BkAM31D_18580	COG1484	DNA-dependent DNA replication
BkAM31D_18585	COG3611	Membrane attachment protein
BkAM31D_18590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BkAM31D_18595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BkAM31D_18600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BkAM31D_18605	COG0237	dephospho-CoA kinase activity
BkAM31D_18610	COG1971	Probably functions as a manganese efflux pump
BkAM31D_18630	COG0330	HflC and HflK could
BkAM31D_18635	COG0330	HflC and HflK could
BkAM31D_18640	COG5002	protein histidine kinase activity
BkAM31D_18645	COG0745	RESPONSE REGULATOR receiver
BkAM31D_18650	COG0039	L-malate dehydrogenase activity
BkAM31D_18655	COG0538	isocitrate dehydrogenase activity
BkAM31D_18660	COG0372	Belongs to the citrate synthase family
BkAM31D_18665	COG2707	UPF0756 membrane protein
BkAM31D_18670	COG3030	protein affecting phage T7 exclusion by the F plasmid
BkAM31D_18680	COG0205	6-phosphofructokinase activity
BkAM31D_18700	COG2186	Transcriptional regulator
BkAM31D_18705	COG0281	malic enzyme
BkAM31D_18710	COG0587	DNA-directed DNA polymerase activity
BkAM31D_18730	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BkAM31D_18755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BkAM31D_18760	COG0006	proline dipeptidase activity
BkAM31D_18770	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_18780	COG0165	Argininosuccinate lyase
BkAM31D_18785	COG0137	argininosuccinate synthase activity
BkAM31D_18795	COG2217	Heavy metal translocating P-type atpase
BkAM31D_18800	COG3481	metal-dependent phosphohydrolase, HD sub domain
BkAM31D_18805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BkAM31D_18820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BkAM31D_18840	COG1714	RDD family
BkAM31D_18845	COG0616	signal peptide processing
BkAM31D_18850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BkAM31D_18870	COG0301	tRNA thio-modification
BkAM31D_18875	COG1104	cysteine desulfurase activity
BkAM31D_18880	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BkAM31D_18885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BkAM31D_18890	COG1309	transcriptional regulator
BkAM31D_18895	COG1956	GAF domain-containing protein
BkAM31D_18900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BkAM31D_18905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BkAM31D_18920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BkAM31D_18925	COG0454	-acetyltransferase
BkAM31D_18930	COG0517	IMP dehydrogenase activity
BkAM31D_18935	COG0123	including yeast histone deacetylase and acetoin utilization protein
BkAM31D_18940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BkAM31D_18950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BkAM31D_18960	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BkAM31D_18960	COG1605	Chorismate mutase
BkAM31D_18965	COG4980	gas vesicle protein
BkAM31D_18975	COG2309	aminopeptidase activity
BkAM31D_18980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BkAM31D_18990	COG1674	ftsk spoiiie
BkAM31D_18995	COG4848	Belongs to the UPF0354 family
BkAM31D_19000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_19025	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BkAM31D_19030	COG1363	Peptidase, m42
BkAM31D_19040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_19045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BkAM31D_19055	COG0510	thiamine kinase activity
BkAM31D_19060	COG1523	belongs to the glycosyl hydrolase 13 family
BkAM31D_19065	COG0788	formyltetrahydrofolate deformylase activity
BkAM31D_19080	COG1346	cytolysis
BkAM31D_19085	COG1380	Effector of murein hydrolase LrgA
BkAM31D_19095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BkAM31D_19100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BkAM31D_19105	COG1349	DNA-binding transcription factor activity
BkAM31D_19110	COG1187	pseudouridine synthase activity
BkAM31D_19120	COG0772	Belongs to the SEDS family
BkAM31D_19125	COG0772	Belongs to the SEDS family
BkAM31D_19140	COG2081	HI0933 family
BkAM31D_19150	COG0495	leucyl-tRNA aminoacylation
BkAM31D_19160	COG2814	Major facilitator Superfamily
BkAM31D_19165	COG1242	4 iron, 4 sulfur cluster binding
BkAM31D_19170	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BkAM31D_19175	COG0288	reversible hydration of carbon dioxide
BkAM31D_19185	COG2267	carboxylic ester hydrolase activity
BkAM31D_19190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BkAM31D_19215	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BkAM31D_19220	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_19230	COG2267	carboxylic ester hydrolase activity
BkAM31D_19235	COG1506	peptidase
BkAM31D_19240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BkAM31D_19245	COG1116	anion transmembrane transporter activity
BkAM31D_19250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BkAM31D_19255	COG0494	nUDIX hydrolase
BkAM31D_19260	COG2814	Major facilitator Superfamily
BkAM31D_19280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BkAM31D_19285	COG0488	(ABC) transporter
BkAM31D_19290	COG1428	Deoxynucleoside kinase
BkAM31D_19295	COG1428	Deoxynucleoside kinase
BkAM31D_19325	COG4974	Belongs to the 'phage' integrase family
BkAM31D_19330	COG2706	6-phosphogluconolactonase activity
BkAM31D_19345	COG2814	Major facilitator Superfamily
BkAM31D_19350	COG0473	3-isopropylmalate dehydrogenase activity
BkAM31D_19355	COG0471	metal ion transport
BkAM31D_19365	COG4565	transcriptional regulatory protein
BkAM31D_19370	COG3290	protein histidine kinase activity
BkAM31D_19380	COG0561	phosphatase activity
BkAM31D_19415	COG1785	Belongs to the alkaline phosphatase family
BkAM31D_19445	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BkAM31D_19450	COG0506	proline dehydrogenase activity
BkAM31D_19455	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_19465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BkAM31D_19470	COG3829	transcription factor binding
BkAM31D_19475	COG1288	antiporter activity
BkAM31D_19485	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BkAM31D_19490	COG3829	transcription factor binding
BkAM31D_19495	COG3829	transcription factor binding
BkAM31D_19600	COG4974	Belongs to the 'phage' integrase family
BkAM31D_19660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_19670	COG4974	Belongs to the 'phage' integrase family
BkAM31D_19680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BkAM31D_19690	COG0166	Belongs to the GPI family
BkAM31D_19695	COG1979	alcohol dehydrogenase
BkAM31D_19700	COG2155	Conserved Protein
BkAM31D_19705	COG1098	S1 RNA binding domain
BkAM31D_19715	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BkAM31D_19720	COG0436	Aminotransferase
BkAM31D_19725	COG1522	sequence-specific DNA binding
BkAM31D_19730	COG1335	isochorismatase
BkAM31D_19740	COG1295	ribonuclease BN
BkAM31D_19745	COG0776	regulation of translation
BkAM31D_19750	COG1714	RDD family
BkAM31D_19755	COG1268	BioY protein
BkAM31D_19760	COG2056	Na+-H+ antiporter family
BkAM31D_19765	COG1131	(ABC) transporter
BkAM31D_19770	COG1725	Transcriptional regulator
BkAM31D_19780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_19785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_19790	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_19795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BkAM31D_19800	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BkAM31D_19810	COG3584	3D domain protein
BkAM31D_19825	COG1252	NADH dehydrogenase
BkAM31D_19830	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_19835	COG0316	Belongs to the HesB IscA family
BkAM31D_19845	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BkAM31D_19855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BkAM31D_19865	COG4844	belongs to the
BkAM31D_19870	COG1252	NADH dehydrogenase
BkAM31D_19885	COG4837	Protein of unknown function (DUF1462)
BkAM31D_19890	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BkAM31D_19900	COG0083	homoserine kinase activity
BkAM31D_19905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BkAM31D_19910	COG0460	homoserine dehydrogenase
BkAM31D_19915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BkAM31D_19920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BkAM31D_19925	COG5002	protein histidine kinase activity
BkAM31D_19930	COG0647	UMP catabolic process
BkAM31D_19940	COG2445	Protein of unknown function DUF86
BkAM31D_19955	COG4470	Protein conserved in bacteria
BkAM31D_19965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BkAM31D_19970	COG0739	heme binding
BkAM31D_20020	COG1757	Na H antiporter
BkAM31D_20035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BkAM31D_20040	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BkAM31D_20045	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BkAM31D_20055	COG1902	pentaerythritol trinitrate reductase activity
BkAM31D_20075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BkAM31D_20095	COG4191	Histidine kinase
BkAM31D_20110	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BkAM31D_20135	COG3377	Domain of unknown function (DUF1805)
BkAM31D_20140	COG0737	Belongs to the 5'-nucleotidase family
BkAM31D_20145	COG0730	response to heat
BkAM31D_20150	COG1801	Protein of unknown function DUF72
BkAM31D_20155	COG0719	Fe-S assembly protein
BkAM31D_20160	COG0822	iron-sulfur transferase activity
BkAM31D_20165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BkAM31D_20170	COG0719	Fe-S assembly protein
BkAM31D_20175	COG0396	ATPase activity
BkAM31D_20185	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BkAM31D_20190	COG1464	Belongs to the NlpA lipoprotein family
BkAM31D_20195	COG2011	ABC-type metal ion transport system permease component
BkAM31D_20200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BkAM31D_20215	COG0509	glycine decarboxylation via glycine cleavage system
BkAM31D_20220	COG1393	Belongs to the ArsC family
BkAM31D_20230	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_20235	COG0183	Belongs to the thiolase family
BkAM31D_20240	COG1024	Enoyl-CoA hydratase
BkAM31D_20240	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_20250	COG5577	PFAM Coat F domain
BkAM31D_20315	COG1192	Involved in chromosome partitioning
BkAM31D_20360	COG5002	protein histidine kinase activity
BkAM31D_20380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BkAM31D_20385	COG0557	exoribonuclease II activity
BkAM31D_20390	COG1647	Serine aminopeptidase, S33
BkAM31D_20420	COG0789	Transcriptional regulator
BkAM31D_20425	COG0655	NAD(P)H dehydrogenase (quinone) activity
BkAM31D_20430	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_20435	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_20460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BkAM31D_20475	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BkAM31D_20490	COG0148	phosphopyruvate hydratase activity
BkAM31D_20495	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BkAM31D_20500	COG0149	triose-phosphate isomerase activity
BkAM31D_20510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BkAM31D_20525	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BkAM31D_20530	COG0740	serine-type endopeptidase activity
BkAM31D_20535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BkAM31D_20540	COG1481	regulation of sporulation
BkAM31D_20545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BkAM31D_20550	COG1660	Displays ATPase and GTPase activities
BkAM31D_20555	COG1051	belongs to the nudix hydrolase family
BkAM31D_20560	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_20565	COG0457	Tetratricopeptide repeat
BkAM31D_20570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BkAM31D_20570	COG0140	phosphoribosyl-ATP diphosphatase activity
BkAM31D_20575	COG0107	imidazoleglycerol-phosphate synthase activity
BkAM31D_20580	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BkAM31D_20585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BkAM31D_20590	COG0131	Imidazoleglycerol-phosphate dehydratase
BkAM31D_20595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BkAM31D_20600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BkAM31D_20605	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BkAM31D_20610	COG0110	maltose O-acetyltransferase activity
BkAM31D_20615	COG0546	phosphoglycolate phosphatase activity
BkAM31D_20620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BkAM31D_20625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BkAM31D_20630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BkAM31D_20635	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BkAM31D_20640	COG1950	PFAM Membrane protein of
BkAM31D_20645	COG1983	PspC domain protein
BkAM31D_20650	COG3595	metallopeptidase activity
BkAM31D_20665	COG0556	nucleotide-excision repair
BkAM31D_20675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BkAM31D_20680	COG0793	Belongs to the peptidase S41A family
BkAM31D_20680	COG3409	Peptidoglycan-binding domain 1 protein
BkAM31D_20685	COG0739	heme binding
BkAM31D_20690	COG2177	Part of the ABC transporter FtsEX involved in
BkAM31D_20695	COG2884	Cell division ATP-binding protein ftsE
BkAM31D_20705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_20710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BkAM31D_20715	COG0653	protein targeting
BkAM31D_20735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BkAM31D_20760	COG1278	Cold shock
BkAM31D_20780	COG1516	flagellar protein fliS
BkAM31D_20800	COG0667	Aldo Keto reductase
BkAM31D_20805	COG1070	Carbohydrate kinase
BkAM31D_20810	COG2115	Belongs to the xylose isomerase family
BkAM31D_20815	COG5578	integral membrane protein
BkAM31D_20825	COG1175	transmembrane transport
BkAM31D_20835	COG1940	carbohydrate kinase activity
BkAM31D_20840	COG3507	Belongs to the glycosyl hydrolase 43 family
BkAM31D_20845	COG3693	PFAM glycoside hydrolase, family 10
BkAM31D_20855	COG0189	ligase activity
BkAM31D_20865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BkAM31D_20870	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BkAM31D_20875	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BkAM31D_20885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BkAM31D_20890	COG4786	Flagellar basal body rod
BkAM31D_20890	COG1256	bacterial-type flagellum assembly
BkAM31D_20910	COG1040	competence protein
BkAM31D_20915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BkAM31D_20985	COG4974	Belongs to the 'phage' integrase family
BkAM31D_20990	COG3655	Transcriptional regulator
BkAM31D_21145	COG0629	single-stranded DNA binding
BkAM31D_21150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BkAM31D_21225	COG3935	DnaD domain protein
BkAM31D_21235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BkAM31D_21255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BkAM31D_21270	COG0745	RESPONSE REGULATOR receiver
BkAM31D_21315	COG1396	sequence-specific DNA binding
BkAM31D_21335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_21340	COG1307	EDD domain protein, DegV family
BkAM31D_21355	COG1739	Uncharacterized protein family UPF0029
BkAM31D_21365	COG0432	Pfam Uncharacterised protein family UPF0047
BkAM31D_21370	COG1388	LysM domain
BkAM31D_21370	COG1705	Flagellar rod assembly protein muramidase FlgJ
BkAM31D_21375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BkAM31D_21380	COG0601	transmembrane transport
BkAM31D_21390	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_21395	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_21400	COG1316	TRANSCRIPTIONal
BkAM31D_21405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BkAM31D_21410	COG4193	domain, Protein
BkAM31D_21420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BkAM31D_21425	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_21430	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BkAM31D_21435	COG1404	Belongs to the peptidase S8 family
BkAM31D_21440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BkAM31D_21465	COG1216	Glycosyl transferase, family 2
BkAM31D_21465	COG1442	glycosyl transferase family 8
BkAM31D_21485	COG1215	transferase activity, transferring glycosyl groups
BkAM31D_21495	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_21510	COG1115	amino acid carrier protein
BkAM31D_21525	COG1316	TRANSCRIPTIONal
BkAM31D_21530	COG3409	Peptidoglycan-binding domain 1 protein
BkAM31D_21530	COG3773	Cell wall hydrolase
BkAM31D_21535	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_21550	COG2203	Gaf domain
BkAM31D_21550	COG2199	diguanylate cyclase activity
BkAM31D_21560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BkAM31D_21565	COG3842	ATPase activity
BkAM31D_21575	COG1176	ABC-type spermidine putrescine transport system, permease component I
BkAM31D_21600	COG3173	Aminoglycoside phosphotransferase
BkAM31D_21605	COG0405	Gamma-glutamyltransferase
BkAM31D_21610	COG1301	dicarboxylic acid transport
BkAM31D_21620	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BkAM31D_21625	COG0697	spore germination
BkAM31D_21640	COG1609	Transcriptional regulator
BkAM31D_21645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_21660	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_21665	COG4638	Rieske (2fe-2S)
BkAM31D_21670	COG1141	Ferredoxin
BkAM31D_21675	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_21690	COG0737	Belongs to the 5'-nucleotidase family
BkAM31D_21690	COG1525	nuclease
BkAM31D_21690	COG4085	toxin activity
BkAM31D_21705	COG4607	ABC-type enterochelin transport system periplasmic component
BkAM31D_21720	COG1114	Component of the transport system for branched-chain amino acids
BkAM31D_21755	COG0583	DNA-binding transcription factor activity
BkAM31D_21760	COG0110	maltose O-acetyltransferase activity
BkAM31D_21765	COG0038	chloride channel
BkAM31D_21800	COG1473	amidohydrolase
BkAM31D_21835	COG1114	Component of the transport system for branched-chain amino acids
BkAM31D_21840	COG1114	Component of the transport system for branched-chain amino acids
BkAM31D_21845	COG0506	proline dehydrogenase activity
BkAM31D_21860	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_21865	COG0583	DNA-binding transcription factor activity
BkAM31D_21875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BkAM31D_21880	COG0405	Gamma-glutamyltransferase
BkAM31D_21895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BkAM31D_21950	COG1414	Transcriptional regulator
BkAM31D_21955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_21965	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_21970	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_21975	COG0697	spore germination
BkAM31D_21995	COG0814	amino acid
BkAM31D_22005	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BkAM31D_22020	COG2755	lipolytic protein G-D-S-L family
BkAM31D_22040	COG2814	Major facilitator Superfamily
BkAM31D_22070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BkAM31D_22100	COG1929	Belongs to the glycerate kinase type-1 family
BkAM31D_22105	COG2610	gluconate transmembrane transporter activity
BkAM31D_22110	COG3835	regulator
BkAM31D_22135	COG0346	lactoylglutathione lyase activity
BkAM31D_22150	COG4187	Peptidase family M20/M25/M40
BkAM31D_22170	COG1288	antiporter activity
BkAM31D_22190	COG0583	DNA-binding transcription factor activity
BkAM31D_22195	COG0010	Belongs to the arginase family
BkAM31D_22200	COG0786	glutamate:sodium symporter activity
BkAM31D_22220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_22225	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_22240	COG1595	DNA-templated transcription, initiation
BkAM31D_22255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BkAM31D_22255	COG0456	acetyltransferase
BkAM31D_22315	COG0753	catalase activity
BkAM31D_22325	COG1595	DNA-templated transcription, initiation
BkAM31D_22340	COG1695	Transcriptional regulator
BkAM31D_22350	COG2364	Membrane
BkAM31D_22370	COG0667	Aldo Keto reductase
BkAM31D_22380	COG0577	efflux transmembrane transporter activity
BkAM31D_22385	COG1136	(ABC) transporter
BkAM31D_22390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BkAM31D_22395	COG4152	abc transporter atp-binding protein
BkAM31D_22420	COG2197	response regulator
BkAM31D_22445	COG2113	Glycine betaine
BkAM31D_22450	COG4176	ABC-type proline glycine betaine transport system permease component
BkAM31D_22455	COG4175	Glycine betaine
BkAM31D_22455	COG0517	IMP dehydrogenase activity
BkAM31D_22460	COG1510	regulation of RNA biosynthetic process
BkAM31D_22480	COG0363	glucosamine-6-phosphate deaminase activity
BkAM31D_22485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BkAM31D_22495	COG4821	SIS domain
BkAM31D_22500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_22510	COG0673	inositol 2-dehydrogenase activity
BkAM31D_22515	COG0395	ABC-type sugar transport system, permease component
BkAM31D_22535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BkAM31D_22550	COG1126	abc transporter atp-binding protein
BkAM31D_22555	COG0765	amino acid transport
BkAM31D_22585	COG2268	Band 7 protein
BkAM31D_22595	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BkAM31D_22600	COG0363	glucosamine-6-phosphate deaminase activity
BkAM31D_22610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_22615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_22630	COG1063	alcohol dehydrogenase
BkAM31D_22635	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_22660	COG0583	DNA-binding transcription factor activity
BkAM31D_22720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BkAM31D_22740	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_22755	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_22760	COG1045	serine acetyltransferase
BkAM31D_22765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BkAM31D_22770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BkAM31D_22785	COG1086	Polysaccharide biosynthesis protein
BkAM31D_22790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BkAM31D_22805	COG4464	protein tyrosine phosphatase activity
BkAM31D_22810	COG0489	protein tyrosine kinase activity
BkAM31D_22815	COG3944	biosynthesis protein
BkAM31D_22820	COG1316	TRANSCRIPTIONal
BkAM31D_22885	COG0791	NLP P60 protein
BkAM31D_22885	COG1388	LysM domain
BkAM31D_22905	COG1349	DNA-binding transcription factor activity
BkAM31D_22910	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_22915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BkAM31D_22920	COG1494	fructose-1,6-bisphosphatase
BkAM31D_22925	COG1461	Dihydroxyacetone kinase
BkAM31D_22930	COG2376	Dihydroxyacetone kinase
BkAM31D_22935	COG0698	ribose 5-phosphate isomerase
BkAM31D_22940	COG2814	Major facilitator Superfamily
BkAM31D_22945	COG1063	alcohol dehydrogenase
BkAM31D_22955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BkAM31D_22995	COG2271	Major facilitator Superfamily
BkAM31D_23000	COG1785	Belongs to the alkaline phosphatase family
BkAM31D_23005	COG0662	Cupin 2, conserved barrel domain protein
BkAM31D_23010	COG1280	lysine exporter protein (LysE YggA)
BkAM31D_23020	COG0789	Transcriptional regulator
BkAM31D_23045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BkAM31D_23050	COG2814	Major facilitator Superfamily
BkAM31D_23095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_23100	COG2323	membrane
BkAM31D_23135	COG0725	ABC transporter, periplasmic molybdate-binding protein
BkAM31D_23140	COG4149	molybdate abc transporter
BkAM31D_23145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BkAM31D_23150	COG3842	ATPase activity
BkAM31D_23155	COG1910	domain protein
BkAM31D_23160	COG3708	Transcriptional regulator
BkAM31D_23160	COG2207	Transcriptional regulator
BkAM31D_23165	COG0596	Alpha beta hydrolase
BkAM31D_23175	COG3773	Cell wall hydrolase
BkAM31D_23185	COG1181	Belongs to the D-alanine--D-alanine ligase family
BkAM31D_23185	COG2918	glutathione biosynthetic process
BkAM31D_23190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BkAM31D_23200	COG1733	regulation of RNA biosynthetic process
BkAM31D_23205	COG5001	Diguanylate cyclase
BkAM31D_23240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BkAM31D_23250	COG2207	Transcriptional regulator
BkAM31D_23250	COG3708	Transcriptional regulator
BkAM31D_23265	COG4372	Transposase
BkAM31D_23270	COG2207	Transcriptional regulator
BkAM31D_23270	COG3708	Transcriptional regulator
BkAM31D_23275	COG0640	Transcriptional regulator
BkAM31D_23345	COG4640	response to antibiotic
BkAM31D_23360	COG2323	membrane
BkAM31D_23365	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_23370	COG2610	gluconate transmembrane transporter activity
BkAM31D_23380	COG3246	L-lysine catabolic process to acetate
BkAM31D_23390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BkAM31D_23395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BkAM31D_23400	COG0583	DNA-binding transcription factor activity
BkAM31D_23420	COG1414	Transcriptional regulator
BkAM31D_23425	COG1309	transcriptional regulator
BkAM31D_23435	COG0697	spore germination
BkAM31D_23440	COG2207	Transcriptional regulator
BkAM31D_23440	COG1917	Cupin 2, conserved barrel domain protein
BkAM31D_23445	COG5646	InterPro IPR014922
BkAM31D_23455	COG2079	MmgE PrpD family protein
BkAM31D_23460	COG1024	Enoyl-CoA hydratase
BkAM31D_23465	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_23470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BkAM31D_23475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BkAM31D_23480	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BkAM31D_23485	COG2086	electron transfer activity
BkAM31D_23490	COG2086	electron transfer activity
BkAM31D_23495	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_23525	COG0247	lactate metabolic process
BkAM31D_23525	COG2181	nitrate reductase activity
BkAM31D_23530	COG0583	DNA-binding transcription factor activity
BkAM31D_23535	COG2814	Major facilitator Superfamily
BkAM31D_23540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BkAM31D_23545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BkAM31D_23565	COG3655	Transcriptional regulator
BkAM31D_23580	COG1879	ABC-type sugar transport system periplasmic component
BkAM31D_23585	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_23590	COG1129	ABC transporter
BkAM31D_23595	COG1869	D-ribose catabolic process
BkAM31D_23600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BkAM31D_23605	COG1609	Transcriptional regulator
BkAM31D_23640	COG0640	Transcriptional regulator
BkAM31D_23645	COG4191	Histidine kinase
BkAM31D_23765	COG0697	spore germination
BkAM31D_23830	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_23835	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_23850	COG0601	transmembrane transport
BkAM31D_23875	COG1595	DNA-templated transcription, initiation
BkAM31D_23890	COG0662	Cupin 2, conserved barrel domain protein
BkAM31D_23915	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_23920	COG0180	Tryptophanyl-tRNA synthetase
BkAM31D_23930	COG1253	flavin adenine dinucleotide binding
BkAM31D_23940	COG0745	RESPONSE REGULATOR receiver
BkAM31D_23945	COG0642	Histidine kinase
BkAM31D_23950	COG1136	(ABC) transporter
BkAM31D_23955	COG0577	efflux transmembrane transporter activity
BkAM31D_23960	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_23980	COG2843	Capsule synthesis protein
BkAM31D_24020	COG1309	transcriptional regulator
BkAM31D_24025	COG5002	protein histidine kinase activity
BkAM31D_24030	COG0745	RESPONSE REGULATOR receiver
BkAM31D_24040	COG1388	LysM domain
BkAM31D_24045	COG3706	GGDEF domain
BkAM31D_24045	COG0745	RESPONSE REGULATOR receiver
BkAM31D_24100	COG3764	Sortase (surface protein transpeptidase)
BkAM31D_24110	COG4191	Histidine kinase
BkAM31D_24140	COG0840	transmembrane signaling receptor activity
BkAM31D_24290	COG4786	Flagellar basal body rod
BkAM31D_24295	COG4786	Flagellar basal body rod
BkAM31D_24300	COG1077	Cell shape determining protein MreB Mrl
BkAM31D_24305	COG1609	Transcriptional regulator
BkAM31D_24320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BkAM31D_24340	COG0739	heme binding
BkAM31D_24345	COG2385	sporulation resulting in formation of a cellular spore
BkAM31D_24350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BkAM31D_24360	COG4836	Membrane
BkAM31D_24365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BkAM31D_24430	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BkAM31D_24435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BkAM31D_24440	COG4475	Protein of unknown function (DUF436)
BkAM31D_24445	COG0698	ribose 5-phosphate isomerase
BkAM31D_24450	COG0840	transmembrane signaling receptor activity
BkAM31D_24455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BkAM31D_24460	COG1971	Probably functions as a manganese efflux pump
BkAM31D_24465	COG0009	L-threonylcarbamoyladenylate synthase
BkAM31D_24485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BkAM31D_24510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BkAM31D_24520	COG1846	Transcriptional regulator
BkAM31D_24530	COG1129	ABC transporter
BkAM31D_24540	COG0559	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_24550	COG0831	urea catabolic process
BkAM31D_24560	COG0804	urea catabolic process
BkAM31D_24565	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BkAM31D_24575	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BkAM31D_24585	COG1435	thymidine kinase activity
BkAM31D_24590	COG0254	rRNA binding
BkAM31D_24595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BkAM31D_24600	COG1494	fructose-1,6-bisphosphatase
BkAM31D_24605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BkAM31D_24610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BkAM31D_24615	COG0191	fructose-bisphosphate aldolase activity
BkAM31D_24620	COG2204	response regulator
BkAM31D_24630	COG0504	CTP synthase activity
BkAM31D_24635	COG3343	RNA polymerase activity
BkAM31D_24640	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BkAM31D_24640	COG1703	isobutyryl-CoA mutase activity
BkAM31D_24640	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BkAM31D_24650	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_24655	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_24660	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_24665	COG0183	Belongs to the thiolase family
BkAM31D_24670	COG0247	lactate metabolic process
BkAM31D_24670	COG2181	nitrate reductase activity
BkAM31D_24675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BkAM31D_24680	COG2267	carboxylic ester hydrolase activity
BkAM31D_24690	COG2839	Protein conserved in bacteria
BkAM31D_24695	COG0018	arginyl-trna synthetase
BkAM31D_24705	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BkAM31D_24710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BkAM31D_24720	COG3465	dGTPase activity
BkAM31D_24725	COG1078	dGTPase activity
BkAM31D_24730	COG4844	belongs to the
BkAM31D_24735	COG0095	Lipoate-protein ligase
BkAM31D_24740	COG0280	phosphate acetyltransferase
BkAM31D_24745	COG1024	Enoyl-CoA hydratase
BkAM31D_24755	COG3773	Cell wall hydrolase
BkAM31D_24765	COG2363	Small membrane protein
BkAM31D_24775	COG0789	Transcriptional regulator
BkAM31D_24790	COG0004	ammonium transporteR
BkAM31D_24800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_24800	COG1263	PTS System
BkAM31D_24805	COG2207	Transcriptional regulator
BkAM31D_24825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BkAM31D_24830	COG2962	Rard protein
BkAM31D_24840	COG0513	Belongs to the DEAD box helicase family
BkAM31D_24845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BkAM31D_24845	COG0723	plastoquinol--plastocyanin reductase activity
BkAM31D_24850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_24855	COG0551	DNA topoisomerase type I activity
BkAM31D_24855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BkAM31D_24860	COG2076	Multidrug Resistance protein
BkAM31D_24865	COG2076	Multidrug Resistance protein
BkAM31D_24875	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BkAM31D_24880	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_24885	COG2814	Major facilitator Superfamily
BkAM31D_24910	COG2094	Belongs to the DNA glycosylase MPG family
BkAM31D_24930	COG1376	ErfK ybiS ycfS ynhG family protein
BkAM31D_24940	COG5582	Belongs to the UPF0302 family
BkAM31D_24950	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BkAM31D_24975	COG2205	protein histidine kinase activity
BkAM31D_24985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BkAM31D_24995	COG2072	flavoprotein involved in K transport
BkAM31D_25000	COG1114	Component of the transport system for branched-chain amino acids
BkAM31D_25005	COG2323	membrane
BkAM31D_25015	COG1115	amino acid carrier protein
BkAM31D_25020	COG0686	Belongs to the AlaDH PNT family
BkAM31D_25025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BkAM31D_25050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BkAM31D_25055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BkAM31D_25065	COG0579	oxidoreductase
BkAM31D_25075	COG0583	DNA-binding transcription factor activity
BkAM31D_25085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BkAM31D_25095	COG2226	methyltransferase
BkAM31D_25100	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BkAM31D_25125	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_25130	COG1120	ATPase activity
BkAM31D_25140	COG1187	pseudouridine synthase activity
BkAM31D_25155	COG2329	Antibiotic biosynthesis monooxygenase
BkAM31D_25160	COG1120	ATPase activity
BkAM31D_25165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_25170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_25175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BkAM31D_25190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BkAM31D_25195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BkAM31D_25205	COG4863	YycH protein
BkAM31D_25210	COG5002	protein histidine kinase activity
BkAM31D_25215	COG0745	RESPONSE REGULATOR receiver
BkAM31D_25220	COG1196	nuclear chromosome segregation
BkAM31D_25220	COG0741	lytic transglycosylase activity
BkAM31D_25220	COG0739	heme binding
BkAM31D_25250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BkAM31D_25255	COG0305	Participates in initiation and elongation during chromosome replication
BkAM31D_25260	COG0359	binds to the 23S rRNA
BkAM31D_25265	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BkAM31D_25270	COG4241	membrane
BkAM31D_25275	COG2610	gluconate transmembrane transporter activity
BkAM31D_25280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BkAM31D_25285	COG1737	Transcriptional regulator
BkAM31D_25290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BkAM31D_25295	COG0629	single-stranded DNA binding
BkAM31D_25300	COG0360	Binds together with S18 to 16S ribosomal RNA
BkAM31D_25305	COG0012	GTP binding
BkAM31D_25310	COG4481	Protein conserved in bacteria
BkAM31D_25315	COG3949	Membrane
BkAM31D_25335	COG1475	DNA binding
BkAM31D_25340	COG1192	Involved in chromosome partitioning
BkAM31D_25345	COG1475	DNA binding
BkAM31D_25350	COG0357	Ribosomal RNA small subunit methyltransferase G
BkAM31D_25355	COG0445	tRNA wobble uridine modification
BkAM31D_25360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BkAM31D_25365	COG1847	R3H domain protein
BkAM31D_25370	COG0706	membrane insertase activity
BkAM31D_25375	COG0594	ribonuclease P activity
BkAM31D_25380	COG0230	Belongs to the bacterial ribosomal protein bL34 family