locus_tag old_locus_tag gene Name start end strand product note type ID NCBI BL14DL4_00001 BL14DL4_00001 nrdA nrdA 8 259 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 DOD-type homing endonuclease domain%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00001 BL14DL4_00002 BL14DL4_00002 BL14DL4_00002 411 635 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 DOD-type homing endonuclease domain%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00002 BL14DL4_00003 BL14DL4_00003 BL14DL4_00003 1440 2596 + Ribonucleoside-diphosphate reductase%3B nonfunctional due to frameshift pseudo gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00003 BL14DL4_00004 BL14DL4_00004 BL14DL4_00004 2674 2925 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00004 BL14DL4_00005 BL14DL4_00005 BL14DL4_00005 3059 3472 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 DOD-type homing endonuclease domain%3B KEGG: bli:BL01192 ribonucleoside-diphosphate reductase alpha chain gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00005 BL14DL4_00006 BL14DL4_00006 BL14DL4_00006 3883 4056 + hypothetical protein gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00006 BL14DL4_00007 BL14DL4_00007 nrdB nrdB 4602 5024 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bsu:BSU17390 ribonucleoside-diphosphate reductase beta chain gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00007 BL14DL4_00008 BL14DL4_00008 BL14DL4_00008 5014 5733 + hypothetical protein gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00008 BL14DL4_00010 BL14DL4_00010 BL14DL4_00010 6063 6449 + hypothetical protein gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00010 BL14DL4_00011 BL14DL4_00011 BL14DL4_00011 6907 7191 + dUTP diphosphatase This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: bsu:BSU17660 dUTP pyrophosphatase gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00011 BL14DL4_00012 BL14DL4_00012 BL14DL4_00012 7267 7707 - hypothetical protein gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00012 BL14DL4_00013 BL14DL4_00013 thyA thyA 8473 8976 + Thymidylate synthase Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bya:BANAU_1833 thymidylate synthase gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00013 BL14DL4_00014 BL14DL4_00014 BL14DL4_00014 9130 9492 + SPBc2 prophage-derived uncharacterized protein YosX gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00014 BL14DL4_00015 BL14DL4_00015 BL14DL4_00015 9482 9712 + hypothetical protein gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00015 BL14DL4_00016 BL14DL4_00016 BL14DL4_00016 9727 10029 + hypothetical protein gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00016 BL14DL4_00017 BL14DL4_00017 BL14DL4_00017 10026 10457 + hypothetical protein gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00017 BL14DL4_00018 BL14DL4_00018 BL14DL4_00018 10418 11089 + hypothetical protein gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00018 BL14DL4_00019 BL14DL4_00019 BL14DL4_00019 11193 11396 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00019 BL14DL4_00020 BL14DL4_00020 BL14DL4_00020 11494 11838 + SPBc2 prophage-derived uncharacterized protein YoqB gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00020 BL14DL4_00021 BL14DL4_00021 BL14DL4_00021 11880 12068 + hypothetical protein gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00021 BL14DL4_00022 BL14DL4_00022 BL14DL4_00022 12102 12275 + SPBc2 prophage-derived uncharacterized membrane protein YotH gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00022 BL14DL4_00023 BL14DL4_00023 BL14DL4_00023 12272 12712 + hypothetical protein gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00023 BL14DL4_00024 BL14DL4_00024 BL14DL4_00024 12754 13203 + hypothetical protein gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00024 BL14DL4_00025 BL14DL4_00025 BL14DL4_00025 13181 13378 + SPBc2 prophage-derived uncharacterized protein YotK gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00025 BL14DL4_00026 BL14DL4_00026 BL14DL4_00026 13404 14006 + SPBc2 prophage-derived uncharacterized protein YotM gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00026 BL14DL4_00027 BL14DL4_00027 BL14DL4_00027 14003 14149 + hypothetical protein gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00027 BL14DL4_00028 BL14DL4_00028 BL14DL4_00028 14231 16201 + Putative DNA recombinase Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of SpoIIIC and SpoIVCB to form sigma K factor. In the N-terminal sectio%3B belongs to the site- specific recombinase resolvase family%3B Contains 1 recombinase DNA-binding domain%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00028 BL14DL4_00029 BL14DL4_00029 BL14DL4_00029 16607 17596 + hypothetical protein gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00029 BL14DL4_00030 BL14DL4_00030 BL14DL4_00030 17619 18173 + uncharacterized protein gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00030 BL14DL4_00031 BL14DL4_00031 BL14DL4_00031 18332 20287 + Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00031 BL14DL4_00032 BL14DL4_00032 BL14DL4_00032 20302 20487 + hypothetical protein gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00032 BL14DL4_00033 BL14DL4_00033 BL14DL4_00033 20764 21222 + Antitoxin YobK Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YobL%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00033 BL14DL4_00034 BL14DL4_00034 BL14DL4_00034 21508 21990 + Repressor rok gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00034 BL14DL4_00035 BL14DL4_00035 BL14DL4_00035 22060 22413 + hypothetical protein gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00035 BL14DL4_00036 BL14DL4_00036 BL14DL4_00036 22555 23814 + putative MFS-type transporter YvqJ Belongs to the major facilitator superfamily gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00036 BL14DL4_00037 BL14DL4_00037 rapK rapK 23925 25031 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bso:BSNT_02017 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00037 BL14DL4_00038 BL14DL4_00038 BL14DL4_00038 25028 25156 + hypothetical protein gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00038 BL14DL4_00039 BL14DL4_00039 BL14DL4_00039 25877 26176 - hypothetical protein gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00039 BL14DL4_00040 BL14DL4_00040 BL14DL4_00040 26195 26449 - hypothetical protein gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00040 BL14DL4_00041 BL14DL4_00041 BL14DL4_00041 26468 26854 - hypothetical protein gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00041 BL14DL4_00042 BL14DL4_00042 cwlA cwlA 26986 28074 - N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00042 BL14DL4_00043 BL14DL4_00043 BL14DL4_00043 28230 30134 - hypothetical protein gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00043 BL14DL4_00044 BL14DL4_00044 BL14DL4_00044 30150 30947 - SPBc2 prophage-derived uncharacterized protein YomF gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00044 BL14DL4_00045 BL14DL4_00045 BL14DL4_00045 30963 33602 - SPBc2 prophage-derived uncharacterized protein YomG Contains 1 fibronectin type-III domain gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00045 BL14DL4_00046 BL14DL4_00046 BL14DL4_00046 33606 34367 - SPBc2 prophage-derived uncharacterized protein YomH gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00046 BL14DL4_00047 BL14DL4_00047 BL14DL4_00047 39541 39955 + Probable tape measure protein%3B nonfunctional due to frameshift pseudo gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00047 BL14DL4_0009 BL14DL4_0009 BL14DL4_0009 5771 6025 + SPBc2 prophage-derived thioredoxin-like protein YosR Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0009 BL14DL4_00100 BL14DL4_00100 BL14DL4_00100 83182 83385 + hypothetical protein gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00100 BL14DL4_00101 BL14DL4_00101 BL14DL4_00101 83558 83752 + hypothetical protein gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00101 BL14DL4_00102 BL14DL4_00102 BL14DL4_00102 83795 83947 + hypothetical protein gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00102 BL14DL4_00103 BL14DL4_00103 BL14DL4_00103 84014 84244 + hypothetical protein gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00103 BL14DL4_00104 BL14DL4_00104 BL14DL4_00104 84280 84699 + hypothetical protein gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00104 BL14DL4_00105 BL14DL4_00105 BL14DL4_00105 84720 84815 + hypothetical protein gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00105 BL14DL4_00106 BL14DL4_00106 BL14DL4_00106 84845 85027 + hypothetical protein gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00106 BL14DL4_00107 BL14DL4_00107 BL14DL4_00107 85024 85236 + hypothetical protein gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00107 BL14DL4_00108 BL14DL4_00108 BL14DL4_00108 85260 85487 + hypothetical protein gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00108 BL14DL4_00109 BL14DL4_00109 BL14DL4_00109 85785 85994 + SPBc2 prophage-derived uncharacterized protein YopB gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00109 BL14DL4_00110 BL14DL4_00110 BL14DL4_00110 86118 87569 + hypothetical protein gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00110 BL14DL4_00111 BL14DL4_00111 BL14DL4_00111 87885 89228 + SPBc2 prophage-derived uncharacterized protein YopC gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00111 BL14DL4_00112 BL14DL4_00112 BL14DL4_00112 89738 90667 + hypothetical protein gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00112 BL14DL4_00113 BL14DL4_00113 BL14DL4_00113 90811 91743 + hypothetical protein gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00113 BL14DL4_00114 BL14DL4_00114 BL14DL4_00114 92109 92447 + hypothetical protein gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00114 BL14DL4_00115 BL14DL4_00115 BL14DL4_00115 92743 92907 + hypothetical protein gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00115 BL14DL4_00116 BL14DL4_00116 BL14DL4_00116 93009 93119 + hypothetical protein gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00116 BL14DL4_00117 BL14DL4_00117 BL14DL4_00117 93173 94603 + hypothetical protein gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00117 BL14DL4_00118 BL14DL4_00118 BL14DL4_00118 94733 95284 + hypothetical protein gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00118 BL14DL4_00119 BL14DL4_00119 BL14DL4_00119 95312 95527 + hypothetical protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00119 BL14DL4_00120 BL14DL4_00120 BL14DL4_00120 95716 96648 + Subtilisin DY Subtilisin is an extracellular alkaline serine protease%2C it catalyzes the hydrolysis of proteins and peptide amides. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: lgy:T479_08580 minor extracellular protease Epr%3B Serine endopeptidases gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00120 BL14DL4_00121 BL14DL4_00121 BL14DL4_00121 96650 97510 + hypothetical protein gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00121 BL14DL4_00122 BL14DL4_00122 BL14DL4_00122 97486 97956 + hypothetical protein gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00122 BL14DL4_00123 BL14DL4_00123 BL14DL4_00123 98129 99298 + SPBc2 prophage-derived uncharacterized protein YopK gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00123 BL14DL4_00124 BL14DL4_00124 BL14DL4_00124 99330 99443 + hypothetical protein gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00124 BL14DL4_00125 BL14DL4_00125 BL14DL4_00125 99714 99917 + hypothetical protein gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00125 BL14DL4_00126 BL14DL4_00126 BL14DL4_00126 99921 100250 + hypothetical protein gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00126 BL14DL4_00127 BL14DL4_00127 BL14DL4_00127 100289 101383 + SPBc2 prophage-derived probable integrase/recombinase YopP Probable recombinase that does not seem to have a role in chromosome dimer resolution per se but rather may have some facilitative role during chromosome partitioning in general%3B Belongs to the 'phage' integrase family gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00127 BL14DL4_00128 BL14DL4_00128 BL14DL4_00128 101451 102827 + SPBc2 prophage-derived uncharacterized protein YopQ gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00128 BL14DL4_00129 BL14DL4_00129 BL14DL4_00129 102831 103832 + SPBc2 prophage-derived uncharacterized protein YopR gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00129 BL14DL4_00130 BL14DL4_00130 BL14DL4_00130 104194 104454 + SPBc2 prophage-derived uncharacterized protein YopT gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00130 BL14DL4_00131 BL14DL4_00131 BL14DL4_00131 104467 104661 + hypothetical protein gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00131 BL14DL4_00132 BL14DL4_00132 BL14DL4_00132 104965 105126 + hypothetical protein gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00132 BL14DL4_00133 BL14DL4_00133 BL14DL4_00133 105269 106423 + Exodeoxyribonuclease V KEGG: azl:AZL_b02900 exodeoxyribonuclease V gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00133 BL14DL4_00134 BL14DL4_00134 BL14DL4_00134 106472 106567 + hypothetical protein gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00134 BL14DL4_00135 BL14DL4_00135 BL14DL4_00135 106548 106688 + hypothetical protein gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00135 BL14DL4_00136 BL14DL4_00136 BL14DL4_00136 106714 107382 + putative SPBc2 prophage-derived protein YoqJ gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00136 BL14DL4_00137 BL14DL4_00137 BL14DL4_00137 107372 107584 + SPBc2 prophage-derived uncharacterized protein YoqK gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00137 BL14DL4_00138 BL14DL4_00138 BL14DL4_00138 107603 107731 + hypothetical protein gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00138 BL14DL4_00139 BL14DL4_00139 BL14DL4_00139 108115 108312 + hypothetical protein gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00139 BL14DL4_00140 BL14DL4_00140 BL14DL4_00140 108359 108703 + hypothetical protein gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00140 BL14DL4_00141 BL14DL4_00141 BL14DL4_00141 108730 108903 + hypothetical protein gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00141 BL14DL4_00142 BL14DL4_00142 BL14DL4_00142 109000 109191 + hypothetical protein gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00142 BL14DL4_00143 BL14DL4_00143 BL14DL4_00143 109412 109624 + hypothetical protein gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00143 BL14DL4_00144 BL14DL4_00144 BL14DL4_00144 109638 110448 + hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00144 BL14DL4_00145 BL14DL4_00145 BL14DL4_00145 110480 110728 + hypothetical protein gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00145 BL14DL4_00146 BL14DL4_00146 ligD ligD 110738 111550 - DNA ligase (ATP) Belongs to the ATP-dependent DNA ligase family gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00146 BL14DL4_00147 BL14DL4_00147 BL14DL4_00147 111643 111867 + SPBc2 prophage-derived uncharacterized protein YoqX gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00147 BL14DL4_00148 BL14DL4_00148 BL14DL4_00148 111864 112226 + hypothetical protein gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00148 BL14DL4_00149 BL14DL4_00149 BL14DL4_00149 112375 112764 + hypothetical protein gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00149 BL14DL4_00150 BL14DL4_00150 BL14DL4_00150 112764 112892 + hypothetical protein gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00150 BL14DL4_00151 BL14DL4_00151 BL14DL4_00151 112937 113068 + hypothetical protein gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00151 BL14DL4_00152 BL14DL4_00152 BL14DL4_00152 113532 113786 + hypothetical protein gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00152 BL14DL4_00153 BL14DL4_00153 BL14DL4_00153 113944 115269 + hypothetical protein gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00153 BL14DL4_00154 BL14DL4_00154 BL14DL4_00154 115295 115666 - hypothetical protein gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00154 BL14DL4_00155 BL14DL4_00155 BL14DL4_00155 115878 116210 + SPBc2 prophage-derived uncharacterized protein YorE gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00155 BL14DL4_00156 BL14DL4_00156 BL14DL4_00156 116294 117208 + SPBc2 prophage-derived uncharacterized protein YorF gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00156 BL14DL4_00157 BL14DL4_00157 BL14DL4_00157 117262 118233 + SPBc2 prophage-derived uncharacterized protein YorG gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00157 BL14DL4_00158 BL14DL4_00158 BL14DL4_00158 118280 118750 + SPBc2 prophage-derived uncharacterized protein YorH gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00158 BL14DL4_00159 BL14DL4_00159 dnaB dnaB 118765 120279 + DNA helicase KEGG: bacy:QF06_20540 replicative DNA helicase gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00159 BL14DL4_00160 BL14DL4_00160 BL14DL4_00160 120296 121429 + SPBc2 prophage-derived uncharacterized protein YorJ gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00160 BL14DL4_00161 BL14DL4_00161 recJ recJ 121433 123154 + Putative SPBc2 prophage-derived single-strand DNA-specific exonuclease YorK Putative single-stranded-DNA-specific exonuclease%3B Belongs to the RecJ family%3B KEGG: bsu:BSU20350 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00161 BL14DL4_00162 BL14DL4_00162 dnaE dnaE 123170 125734 + DNA-directed DNA polymerase Replicates viral genomic DNA%3B Belongs to the DNA polymerase type-C family%3B KEGG: bsu:BSU20340 DNA polymerase III subunit alpha gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00162 BL14DL4_00163 BL14DL4_00163 BL14DL4_00163 125918 126688 + hypothetical protein gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00163 BL14DL4_00164 BL14DL4_00164 BL14DL4_00164 126738 128111 + DNA-directed DNA polymerase Replicates viral genomic DNA%3B Belongs to the DNA polymerase type-C family%3B KEGG: bsu:BSU20340 DNA polymerase III subunit alpha gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00164 BL14DL4_00165 BL14DL4_00165 BL14DL4_00165 128122 128838 + SPBc2 prophage-derived uncharacterized protein YorM gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00165 BL14DL4_00166 BL14DL4_00166 BL14DL4_00166 128843 129058 + hypothetical protein gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00166 BL14DL4_00167 BL14DL4_00167 BL14DL4_00167 129055 129207 + hypothetical protein gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00167 BL14DL4_00168 BL14DL4_00168 BL14DL4_00168 129227 129388 + SPBc2 prophage-derived uncharacterized protein YorQ gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00168 BL14DL4_00169 BL14DL4_00169 BL14DL4_00169 129382 129969 + hypothetical protein gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00169 BL14DL4_00170 BL14DL4_00170 BL14DL4_00170 129990 130334 - hypothetical protein gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00170 BL14DL4_00171 BL14DL4_00171 BL14DL4_00171 131341 131811 + SPBc2 prophage-derived uncharacterized protein YosC gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00171 BL14DL4_00172 BL14DL4_00172 BL14DL4_00172 131845 131970 + hypothetical protein gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00172 BL14DL4_00173 BL14DL4_00173 BL14DL4_00173 131990 132352 + hypothetical protein gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00173 BL14DL4_00174 BL14DL4_00174 BL14DL4_00174 132367 132498 + hypothetical protein gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00174 BL14DL4_00175 BL14DL4_00175 BL14DL4_00175 132520 133197 + Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00175 BL14DL4_00176 BL14DL4_00176 BL14DL4_00176 133256 133447 + hypothetical protein gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00176 BL14DL4_00177 BL14DL4_00177 BL14DL4_00177 133688 133822 + SPBc2 prophage-derived uncharacterized protein YosI gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00177 BL14DL4_00178 BL14DL4_00178 BL14DL4_00178 133839 134012 + hypothetical protein gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00178 BL14DL4_00179 BL14DL4_00179 BL14DL4_00179 134026 134229 + hypothetical protein gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00179 BL14DL4_00180 BL14DL4_00180 BL14DL4_00180 134252 134512 + hypothetical protein gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00180 BL14DL4_00181 BL14DL4_00181 BL14DL4_00181 134565 134912 + SPBc2 prophage-derived uncharacterized protein YosL gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00181 BL14DL4_00182 BL14DL4_00182 BL14DL4_00182 134912 135313 + SPBc2 prophage-derived protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00182 BL14DL4_00183 BL14DL4_00183 BL14DL4_00183 135270 135998 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bcl:ABC3108 ribonucleoside-diphosphate reductase alpha chain gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00183 BL14DL4_00184 BL14DL4_00184 BL14DL4_00184 136419 138779 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B Contains 1 DOD-type homing endonuclease domain%3B KEGG: beo:BEH_07960 ribonucleoside-diphosphate reductase alpha chain gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00184 BL14DL4_00185 BL14DL4_00185 BL14DL4_00185 138996 139244 + hypothetical protein gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00185 BL14DL4_00186 BL14DL4_00186 BL14DL4_00186 139257 139430 + hypothetical protein gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00186 BL14DL4_00187 BL14DL4_00187 BL14DL4_00187 139431 140402 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bamy:V529_20170 ribonucleoside-diphosphate reductase beta chain gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00187 BL14DL4_00188 BL14DL4_00188 BL14DL4_00188 140392 141111 + hypothetical protein gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00188 BL14DL4_00189 BL14DL4_00189 BL14DL4_00189 141149 141403 + SPBc2 prophage-derived thioredoxin-like protein YosR Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00189 BL14DL4_00190 BL14DL4_00190 BL14DL4_00190 141441 141827 + hypothetical protein gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00190 BL14DL4_00191 BL14DL4_00191 BL14DL4_00191 142285 142572 + dUTP diphosphatase This enzyme is involved in nucleotide metabolism: it produces dUMP%2C the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA%3B Belongs to the dUTPase family%3B KEGG: bsu:BSU17660 dUTP pyrophosphatase gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00191 BL14DL4_00192 BL14DL4_00192 BL14DL4_00192 142644 143084 - hypothetical protein gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00192 BL14DL4_00193 BL14DL4_00193 BL14DL4_00193 143215 143502 + SPBc2 prophage-derived uncharacterized protein YosV gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00193 BL14DL4_00194 BL14DL4_00194 BL14DL4_00194 143504 144355 + Thymidylate synthase Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bya:BANAU_1833 thymidylate synthase gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00194 BL14DL4_00195 BL14DL4_00195 BL14DL4_00195 144509 144871 + SPBc2 prophage-derived uncharacterized protein YosX gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00195 BL14DL4_00196 BL14DL4_00196 BL14DL4_00196 144861 145091 + hypothetical protein gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00196 BL14DL4_00197 BL14DL4_00197 BL14DL4_00197 145106 145408 + hypothetical protein gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00197 BL14DL4_00198 BL14DL4_00198 BL14DL4_00198 145405 146469 + hypothetical protein gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00198 BL14DL4_00199 BL14DL4_00199 BL14DL4_00199 146573 146776 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00199 BL14DL4_00200 BL14DL4_00200 BL14DL4_00200 146874 147218 + SPBc2 prophage-derived uncharacterized protein YoqB gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00200 BL14DL4_00201 BL14DL4_00201 BL14DL4_00201 147260 147448 + hypothetical protein gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00201 BL14DL4_00202 BL14DL4_00202 BL14DL4_00202 147482 147655 + SPBc2 prophage-derived uncharacterized membrane protein YotH gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00202 BL14DL4_00203 BL14DL4_00203 BL14DL4_00203 147652 148092 + hypothetical protein gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00203 BL14DL4_00204 BL14DL4_00204 BL14DL4_00204 148134 148583 + hypothetical protein gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00204 BL14DL4_00205 BL14DL4_00205 BL14DL4_00205 148561 148758 + SPBc2 prophage-derived uncharacterized protein YotK gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00205 BL14DL4_00206 BL14DL4_00206 BL14DL4_00206 148784 149386 + SPBc2 prophage-derived uncharacterized protein YotM gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00206 BL14DL4_00207 BL14DL4_00207 BL14DL4_00207 149383 149529 + hypothetical protein gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00207 BL14DL4_00208 BL14DL4_00208 BL14DL4_00208 149611 151302 + Putative DNA recombinase Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of SpoIIIC and SpoIVCB to form sigma K factor. In the N-terminal sectio%3B belongs to the site- specific recombinase resolvase family%3B Contains 1 recombinase DNA-binding domain%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00208 BL14DL4_00209 BL14DL4_00209 BL14DL4_00209 151292 151699 + Protein cbbX like protein%2C chloroplastic Seems to be necessary for the expression of RuBisCO. Belongs to the cbxX/cfxQ family gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00209 BL14DL4_00210 BL14DL4_00210 BL14DL4_00210 151803 153065 + GTPase HflX GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family%3B Contains 1 Hflx-type G (guanine nucleotide-binding) domain gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00210 BL14DL4_00211 BL14DL4_00211 BL14DL4_00211 153084 154349 + Cystathionine gamma-lyase KEGG: ava:Ava_4213 cystathionine gamma-lyase gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00211 BL14DL4_00212 BL14DL4_00212 BL14DL4_00212 154452 154859 + HTH-type transcriptional regulator GlnR Represses many genes including the glnRA operon and tnrA during growth with nitrogen excess%3B Contains 1 HTH merR-type DNA-binding domain gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00212 BL14DL4_00213 BL14DL4_00213 glnA glnA 154916 156250 + Glutamate--ammonia ligase Belongs to the glutamine synthetase family%3B KEGG: bsu:BSU17460 glutamine synthetase gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00213 BL14DL4_00214 BL14DL4_00214 BL14DL4_00214 156582 156785 + hypothetical protein gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00214 BL14DL4_00215 BL14DL4_00215 BL14DL4_00215 156868 157035 - hypothetical protein gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00215 BL14DL4_00216 BL14DL4_00216 BL14DL4_00216 157890 158357 + hypothetical protein gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00216 BL14DL4_00217 BL14DL4_00217 BL14DL4_00217 158359 159795 + hypothetical protein gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00217 BL14DL4_00218 BL14DL4_00218 BL14DL4_00218 159922 160239 - hypothetical protein gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00218 BL14DL4_00219 BL14DL4_00219 BL14DL4_00219 160592 161020 + putative HIT-like protein Contains 1 HIT domain gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00219 BL14DL4_00220 BL14DL4_00220 BL14DL4_00220 161180 161596 + hypothetical protein gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00220 BL14DL4_00221 BL14DL4_00221 BL14DL4_00221 161664 161966 + hypothetical protein gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00221 BL14DL4_00222 BL14DL4_00222 BL14DL4_00222 162200 163177 + uncharacterized protein gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00222 BL14DL4_00223 BL14DL4_00223 BL14DL4_00223 163240 163482 + hypothetical protein gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00223 BL14DL4_00224 BL14DL4_00224 BL14DL4_00224 163535 164014 + hypothetical protein gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00224 BL14DL4_00225 BL14DL4_00225 tehB tehB 164156 164752 + Tellurite methyltransferase KEGG: pmu:PM0656 tellurite methyltransferase gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00225 BL14DL4_00226 BL14DL4_00226 BL14DL4_00226 164691 165338 + uncharacterized protein gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00226 BL14DL4_00227 BL14DL4_00227 BL14DL4_00227 165372 165947 + hypothetical protein gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00227 BL14DL4_00228 BL14DL4_00228 BL14DL4_00228 166108 166584 + Repressor rok gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00228 BL14DL4_00229 BL14DL4_00229 BL14DL4_00229 166643 166876 + hypothetical protein gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00229 BL14DL4_00230 BL14DL4_00230 BL14DL4_00230 167225 167845 - hypothetical protein gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00230 BL14DL4_00231 BL14DL4_00231 BL14DL4_00231 168559 169143 + putative HTH-type transcriptional regulator YvdT Contains 1 HTH tetR-type DNA-binding domain gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00231 BL14DL4_00232 BL14DL4_00232 BL14DL4_00232 169225 169560 + putative membrane protein YvdS Belongs to the small multidrug resistance (SMR) protein family gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00232 BL14DL4_00233 BL14DL4_00233 BL14DL4_00233 169557 169877 + Spermidine export protein MdtJ Catalyzes the excretion of spermidine%3B Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00233 BL14DL4_00234 BL14DL4_00234 speG speG 169906 170448 + Diamine N-acetyltransferase Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: van:VAA_01303 diamine N-acetyltransferase gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00234 BL14DL4_00235 BL14DL4_00235 BL14DL4_00235 170486 170842 - hypothetical protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00235 BL14DL4_00236 BL14DL4_00236 BL14DL4_00236 171026 171460 + uncharacterized protein gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00236 BL14DL4_00237 BL14DL4_00237 BL14DL4_00237 171794 172003 + Thiol-disulfide oxidoreductase ResA Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00237 BL14DL4_00238 BL14DL4_00238 BL14DL4_00238 172152 173015 + uncharacterized protein Belongs to the manganese catalase family gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00238 BL14DL4_00239 BL14DL4_00239 BL14DL4_00239 173100 173900 + hypothetical protein gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00239 BL14DL4_00240 BL14DL4_00240 rimJ rimJ 174032 174550 + Ribosomal-protein-alanine N-acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC2051 ribosomal-protein-alanine N-acetyltransferase gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00240 BL14DL4_00241 BL14DL4_00241 BL14DL4_00241 174543 174845 + hypothetical protein gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00241 BL14DL4_00242 BL14DL4_00242 BL14DL4_00242 175164 175742 + putative HTH-type transcriptional regulator YuxN Contains 1 HTH tetR-type DNA-binding domain gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00242 BL14DL4_00243 BL14DL4_00243 BL14DL4_00243 175973 176428 + HTH-type transcriptional regulator MhqR Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00243 BL14DL4_00244 BL14DL4_00244 BL14DL4_00244 176501 177124 + Putative NAD(P)H nitroreductase YdgI Belongs to the nitroreductase family%3B KEGG: bsr:I33_0620 putative NAD(P)H nitroreductase%3B Oxidoreductases gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00244 BL14DL4_00245 BL14DL4_00245 BL14DL4_00245 177160 178098 + Putative ring-cleaving dioxygenase MhqO Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00245 BL14DL4_00246 BL14DL4_00246 BL14DL4_00246 178120 178728 + uncharacterized protein Belongs to the flavoredoxin family gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00246 BL14DL4_00247 BL14DL4_00247 wrbA wrbA 178929 179540 + NAD(P)H dehydrogenase (quinone) It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide (By similarity)%3B Belongs to the WrbA family%3B Contains 1 flavodoxin-like domain%3B KEGG: bli:BL02638 NAD(P)H dehydrogenase (quinone) gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00247 BL14DL4_00248 BL14DL4_00248 BL14DL4_00248 179994 180827 + hypothetical protein gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00248 BL14DL4_00249 BL14DL4_00249 BL14DL4_00249 180921 181679 + hypothetical protein gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00249 BL14DL4_00250 BL14DL4_00250 BL14DL4_00250 181739 182578 + Thymidylate synthase Provides the sole de novo source of dTMP for DNA biosynthesis%3B Belongs to the thymidylate synthase family. Bacterial- type ThyA subfamily%3B KEGG: bli:BL02642 thymidylate synthase gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00250 BL14DL4_00251 BL14DL4_00251 BL14DL4_00251 182937 183365 + Sporulation-specific extracellular nuclease Degrades both double-stranded linear and covalently closed circular DNA. Likely to play a scavenging role in order to supply nutrients under starvation conditions. To B. subtilis NucA/ComI gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00251 BL14DL4_00252 BL14DL4_00252 lexA lexA 183561 184184 - Repressor LexA Represses a number of genes involved in the response to DNA damage (SOS response)%2C including recA and lexA. In the presence of single-stranded DNA%2C RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA%2C leading to derepression of the SOS regulon and eventually DNA repair%3B Belongs to the peptidase S24 family%3B KEGG: pae:PA3007 repressor LexA gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00252 BL14DL4_00253 BL14DL4_00253 BL14DL4_00253 184331 184648 + Cell division suppressor protein YneA Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly%2C after the assembly of the Z ring%2C by probably suppressing recruitment of FtsL and/or DivIC to the division machinery%3B Belongs to the YneA family gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00253 BL14DL4_00254 BL14DL4_00254 BL14DL4_00254 184667 185314 + Resolvase like protein YneB Belongs to the site-specific recombinase resolvase family%3B Contains 1 resolvase/invertase-type recombinase catalytic domain gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00254 BL14DL4_00255 BL14DL4_00255 BL14DL4_00255 185380 185613 + 5-formyltetrahydrofolate cyclo-ligase Belongs to the UPF0291 family%3B KEGG: rum:CK1_06990 5-formyltetrahydrofolate cyclo-ligase gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00255 BL14DL4_00256 BL14DL4_00256 tktA tktA 185780 187783 + Transketolase Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor%2C via a covalent intermediate with the cofactor thiamine pyrophosphate%3B Belongs to the transketolase family%3B KEGG: bsu:BSU17890 transketolase gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00256 BL14DL4_00257 BL14DL4_00257 BL14DL4_00257 187938 188375 + Sporulation inhibitor of replication protein SirA Inhibits DNA replication in growing cells%2C thus reducing chromosome copy number and playing a significant role during the onset of sporulation gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00257 BL14DL4_00258 BL14DL4_00258 BL14DL4_00258 188460 188678 + UPF0154 protein Belongs to the UPF0154 family gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00258 BL14DL4_00259 BL14DL4_00259 BL14DL4_00259 188759 188920 - Aspartyl-phosphate phosphatase YnzD Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00259 BL14DL4_00260 BL14DL4_00260 BL14DL4_00260 189163 189870 + Cytochrome c-type bioproteinis protein CcdA Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00260 BL14DL4_00261 BL14DL4_00261 BL14DL4_00261 189952 190323 + Protein CcdB Contains 1 response regulatory domain gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00261 BL14DL4_00262 BL14DL4_00262 BL14DL4_00262 190406 190891 + Protein CcdC gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00262 BL14DL4_00263 BL14DL4_00263 BL14DL4_00263 190927 191355 - uncharacterized protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00263 BL14DL4_00264 BL14DL4_00264 BL14DL4_00264 191560 191967 - Spore coat protein gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00264 BL14DL4_00265 BL14DL4_00265 acnA acnA 192672 195398 + Aconitate hydratase Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also able to catalyze the hydration of cis-homoaconitate to yield (R)-homocitrate%2C but with a lower efficiency (PubMed:23106124). Could catalyze the hydration of 2- methyl-cis-aconitate to yield (2R%2C3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein (By similarity)%3B Belongs to the aconitase/IPM isomerase family%3B KEGG: bli:BL02940 aconitate hydratase gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00265 BL14DL4_00266 BL14DL4_00266 BL14DL4_00266 195470 195976 + Thiol-disulfide oxidoreductase ResA Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached. Does not play a role in sporulation%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00266 BL14DL4_00267 BL14DL4_00267 BL14DL4_00267 196048 196173 + uncharacterized protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00267 BL14DL4_00268 BL14DL4_00268 BL14DL4_00268 196242 196385 + Small%2C acid-soluble spore protein Belongs to the SspN family gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00268 BL14DL4_00269 BL14DL4_00269 BL14DL4_00269 196411 196647 + Small%2C acid-soluble spore protein Tlp Belongs to the Tlp family gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00269 BL14DL4_00270 BL14DL4_00270 ybgC ybgC 196754 197170 + Putative acyl-CoA thioesterase YneP Has acyl-CoA thioesterase activity%3B Belongs to the 4-hydroxybenzoyl-CoA thioesterase family%3B KEGG: bsr:I33_2017 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00270 BL14DL4_00271 BL14DL4_00271 nadE nadE 197170 197472 + NAD(+) synthase KEGG: ble:BleG1_2142 NAD+ synthase gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00271 BL14DL4_00272 BL14DL4_00272 BL14DL4_00272 197704 198066 - hypothetical protein gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00272 BL14DL4_00273 BL14DL4_00273 BL14DL4_00273 198411 199442 - hypothetical protein gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00273 BL14DL4_00274 BL14DL4_00274 BL14DL4_00274 199766 200053 - uncharacterized protein Belongs to the HesB/IscA family gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00274 BL14DL4_00275 BL14DL4_00275 plsY plsY 200156 200749 - Glycerol-3-phosphate 1-O-acyltransferase Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor%2C but not acyl-CoA or acyl-ACP%3B Belongs to the PlsY family%3B KEGG: bli:BL02954 glycerol-3-phosphate acyltransferase PlsY gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00275 BL14DL4_00276 BL14DL4_00276 BL14DL4_00276 200928 201341 + uncharacterized protein gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00276 BL14DL4_00277 BL14DL4_00277 parE parE 201659 203632 + DNA topoisomerase 4 subunit Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bli:BL01186 topoisomerase IV subunit B%3B Other isomerases gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00277 BL14DL4_00278 BL14DL4_00278 parC parC 203637 206060 + DNA topoisomerase 4 subunit Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily%3B KEGG: bsu:BSU18100 topoisomerase IV subunit A%3B Other isomerases gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00278 BL14DL4_00279 BL14DL4_00279 BL14DL4_00279 206362 207453 - Arabinose metabolism transcriptional repressor Transcriptional repressor of the arabinose utilization genes%3B Contains 1 HTH gntR-type DNA-binding domain gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00279 BL14DL4_00280 BL14DL4_00280 araB araB 207806 209413 + Ribulokinase KEGG: lme:LEUM_0854 L-ribulokinase gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00280 BL14DL4_00281 BL14DL4_00281 araD araD 209427 210122 + L-ribulose-5-phosphate 4-epimerase Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization (By similarity)%3B Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: ype:YPO2230 L-ribulose-5-phosphate 4-epimerase gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00281 BL14DL4_00282 BL14DL4_00282 araA araA 210178 211602 + L-arabinose isomerase Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bli:BL01182 L-arabinose isomerase gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00282 BL14DL4_00283 BL14DL4_00283 BL14DL4_00283 211886 213280 + D-xylose-proton symporter Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system)%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00283 BL14DL4_00284 BL14DL4_00284 fabG fabG 213851 214633 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ppb:PPUBIRD1_2441 3-oxoacyl-(acyl-carrier protein) reductase gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00284 BL14DL4_00285 BL14DL4_00285 BL14DL4_00285 214957 215082 - hypothetical protein gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00285 BL14DL4_00286 BL14DL4_00286 BL14DL4_00286 215111 215455 - hypothetical protein gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00286 BL14DL4_00287 BL14DL4_00287 BL14DL4_00287 215783 217195 + Amino-acid carrier protein AlsT Belongs to the sodium:alanine (SAF) symporter family gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00287 BL14DL4_00288 BL14DL4_00288 BL14DL4_00288 217240 217584 - hypothetical protein gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00288 BL14DL4_00289 BL14DL4_00289 narI narI 217697 218383 - Nitrate reductase KEGG: bli:BL01175 nitrate reductase gamma subunit gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00289 BL14DL4_00290 BL14DL4_00290 BL14DL4_00290 218380 218922 - putative nitrate reductase molybdenum cofactor assembly chaperone NarJ Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase%3B Belongs to the NarJ/NarW family gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00290 BL14DL4_00291 BL14DL4_00291 narH narH 218941 220410 - Nitrate reductase Contains 3 4Fe-4S ferredoxin-type domains%3B KEGG: sod:Sant_0172 nitrate reductase beta subunit gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00291 BL14DL4_00292 BL14DL4_00292 narG narG 220400 224086 - Nitrate reductase The alpha chain is the actual site of nitrate reduction. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU37280 nitrate reductase alpha subunit gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00292 BL14DL4_00293 BL14DL4_00293 BL14DL4_00293 224261 225502 - hypothetical protein gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00293 BL14DL4_00294 BL14DL4_00294 BL14DL4_00294 225499 225741 - hypothetical protein gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00294 BL14DL4_00295 BL14DL4_00295 BL14DL4_00295 225830 226933 - Coenzyme PQQ synthesis protein Belongs to the radical SAM superfamily. PqqE family gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00295 BL14DL4_00296 BL14DL4_00296 BL14DL4_00296 227048 227515 - putative transcription regulator ArfM Activates%2C in anaerobic conditions%2C the transcription of the fermentative operons lctEP and alsDS%2C of the hmp gene encoding a flavohemoglobin-like protein%2C the nitrite reductase operon nasDE and the heme biosynthesis genes hemN and hemZ gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00296 BL14DL4_00297 BL14DL4_00297 BL14DL4_00297 227665 228387 + uncharacterized protein To H. influenzae HI_1626 gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00297 BL14DL4_00298 BL14DL4_00298 BL14DL4_00298 228433 229146 - Anaerobic regulatory protein It is involved in the activation of genes necessary for anaerobic respiration. Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00298 BL14DL4_00299 BL14DL4_00299 BL14DL4_00299 229292 230476 - Nitrite extrusion protein Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate. Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00299 BL14DL4_00300 BL14DL4_00300 BL14DL4_00300 230698 230937 + hypothetical protein gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00300 BL14DL4_00301 BL14DL4_00301 BL14DL4_00301 230900 231649 + CRP-like cAMP-activated global transcriptional regulator Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites%2C causing DNA- bending%2C to regulate transcription. cAMP improves binding to specific DNA sequences%2C probably by altering protein conformation. Involved in the regulation of gntP and gntK genes%2C which are involved in gluconate metabolism (PubMed:16385030). May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes (PubMed:15150232). It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole carbon source%2C however because the cytosolic cAMP level is elevated in the presence of glucose and low upon growth on acetate%2C it is conceivable that it is unable to function as an activator under acetate conditions (PubMed:18355281)%3B Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00301 BL14DL4_00302 BL14DL4_00302 norB norB 231806 234160 + Nitric-oxide reductase (cytochrome c) Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity)%3B Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL01473 nitric oxide reductase subunit B gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00302 BL14DL4_00303 BL14DL4_00303 BL14DL4_00303 234205 234918 - Iron-sulfur cluster repair protein YtfE Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions%3B Belongs to the RIC family. YtfE subfamily gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00303 BL14DL4_00304 BL14DL4_00304 BL14DL4_00304 235084 235455 + UPF0713 protein YngL Belongs to the UPF0713 family gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00304 BL14DL4_00305 BL14DL4_00305 BL14DL4_00305 235825 237453 + Cellulase Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: bld:BLi02088 endoglucanase gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00305 BL14DL4_00306 BL14DL4_00306 BL14DL4_00306 237501 237758 + uncharacterized protein gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00306 BL14DL4_00307 BL14DL4_00307 BL14DL4_00307 237785 238291 + Ribosomal-protein-alanine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: pat:Patl_0113 ribosomal-protein-alanine N-acetyltransferase gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00307 BL14DL4_00308 BL14DL4_00308 BL14DL4_00308 238942 239121 - hypothetical protein gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00308 BL14DL4_00309 BL14DL4_00309 BL14DL4_00309 239189 239437 + hypothetical protein gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00309 BL14DL4_00310 BL14DL4_00310 BL14DL4_00310 239567 240124 - hypothetical protein gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00310 BL14DL4_00311 BL14DL4_00311 BL14DL4_00311 240147 240320 - hypothetical protein gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00311 BL14DL4_00312 BL14DL4_00312 BL14DL4_00312 240517 241326 - putative MFS-type transporter Belongs to the major facilitator superfamily gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00312 BL14DL4_00313 BL14DL4_00313 BL14DL4_00313 241604 243010 - uncharacterized protein Contains 8 PbH1 repeats gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00313 BL14DL4_00314 BL14DL4_00314 BL14DL4_00314 243148 244464 - Branched-chain amino acid transport system carrier protein BrnQ Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00314 BL14DL4_00315 BL14DL4_00315 yahK yahK 245026 245892 - putative formaldehyde dehydrogenase AdhA Functions in the protection against aldehyde-stress%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: care:LT85_0355 uncharacterized zinc-type alcohol dehydrogenase-like protein%3B Oxidoreductases gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00315 BL14DL4_00316 BL14DL4_00316 BL14DL4_00316 246290 246685 + putative HTH-type transcriptional regulator Contains 1 HTH merR-type DNA-binding domain gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00316 BL14DL4_00317 BL14DL4_00317 BL14DL4_00317 246712 246975 - Phosphocarrier protein HPr General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity)%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00317 BL14DL4_00318 BL14DL4_00318 BL14DL4_00318 247173 248273 - N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D Hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce N-acylethanolamines (NAEs) and phosphatidic acid. Responsible for the generation of anandamide (N- arachidonoylethanolamine)%2C the ligand of cannabinoid and vanilloid receptors (By similarity)%3B Belongs to the NAPE-PLD family%3B KEGG: hmg:100205873 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00318 BL14DL4_00319 BL14DL4_00319 BL14DL4_00319 248491 248943 - hypothetical protein gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00319 BL14DL4_00320 BL14DL4_00320 paaF paaF 249014 250075 - Enoyl-CoA hydratase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: ngl:RG1141_CH32070 enoyl-CoA hydratase gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00320 BL14DL4_00321 BL14DL4_00321 fadB fadB 250091 250876 - Enoyl-CoA hydratase Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: blh:BaLi_c21690 enoyl-CoA hydratase gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00321 BL14DL4_00322 BL14DL4_00322 mmsA mmsA 250959 252413 - Malonate-semialdehyde dehydrogenase (acetylating) Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: bli:BL00293 malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00322 BL14DL4_00323 BL14DL4_00323 garR garR 252432 253319 - 2-hydroxy-3-oxopropionate reductase Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: pae:PA1500 2-hydroxy-3-oxopropionate reductase gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00323 BL14DL4_00324 BL14DL4_00324 BL14DL4_00324 253335 255050 - putative acyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bli:BL00291 null%3B With other acceptors gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00324 BL14DL4_00325 BL14DL4_00325 manA manA 255508 256461 - Mannose-6-phosphate isomerase Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bli:BL00290 mannose-6-phosphate isomerase gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00325 BL14DL4_00326 BL14DL4_00326 fruA fruA 256480 258423 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. Contains 2 PTS EIIB type-2 domains%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: pse:NH8B_1236 PTS system%2C fructose-specific IIB component gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00326 BL14DL4_00327 BL14DL4_00327 BL14DL4_00327 258826 259167 + hypothetical protein gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00327 BL14DL4_00328 BL14DL4_00328 BL14DL4_00328 259646 259816 - hypothetical protein gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00328 BL14DL4_00329 BL14DL4_00329 BL14DL4_00329 259971 260243 - hypothetical protein gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00329 BL14DL4_00330 BL14DL4_00330 BL14DL4_00330 260358 262301 - Transcriptional regulator ManR Positively regulates the expression of the mannose operon that consists of three genes%2C manP%2C manA%2C and yjdF%2C which are responsible for the transport and utilization of mannose. Also activates its own expression%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00330 BL14DL4_00331 BL14DL4_00331 BL14DL4_00331 262607 263263 - hypothetical protein gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00331 BL14DL4_00332 BL14DL4_00332 BL14DL4_00332 263247 264125 - Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00332 BL14DL4_00333 BL14DL4_00333 BL14DL4_00333 264128 264502 - putative HTH-type transcriptional regulator YhcF Contains 1 HTH gntR-type DNA-binding domain gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00333 BL14DL4_00334 BL14DL4_00334 BL14DL4_00334 264792 265643 - putative oxidoreductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bha:BH0707 null%3B Oxidoreductases gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00334 BL14DL4_00335 BL14DL4_00335 uxuA uxuA 265681 266751 - Mannonate dehydratase Catalyzes the dehydration of D-mannonate%3B Belongs to the mannonate dehydratase family%3B KEGG: rpj:N234_35380 mannonate dehydratase gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00335 BL14DL4_00336 BL14DL4_00336 malZ malZ 266996 269404 - Alpha-glucosidase Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity (By similarity)%3B Belongs to the glycosyl hydrolase 31 family%3B KEGG: bli:BL00280 alpha-glucosidase gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00336 BL14DL4_00337 BL14DL4_00337 BL14DL4_00337 269424 270719 - uncharacterized protein Belongs to the YiaN/YgiK family gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00337 BL14DL4_00338 BL14DL4_00338 BL14DL4_00338 270758 271273 - Putative TRAP transporter small permease protein Belongs to the TRAP transporter small permease family gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00338 BL14DL4_00339 BL14DL4_00339 BL14DL4_00339 271324 272334 - C4-dicarboxylate-binding protein DctB Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not directly involved in C4-dicarboxylate uptake%2C but plays a sensory role in the DctS/DctR two-component system which regulates the expression of the dctA C4-dicarboxylate transporter%3B Belongs to the bacterial solute-binding protein 7 family gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00339 BL14DL4_00340 BL14DL4_00340 BL14DL4_00340 272793 273803 + Catabolite control protein A Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions%3B Contains 1 HTH lacI-type DNA-binding domain gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00340 BL14DL4_00341 BL14DL4_00341 arsC arsC 274018 274437 - Arsenate reductase (glutaredoxin) Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins%2C low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family%3B KEGG: bsr:I33_0599 arsenate reductase gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00341 BL14DL4_00342 BL14DL4_00342 BL14DL4_00342 274460 275755 - Arsenical pump membrane protein Involved in arsenical resistance. Thought to form the channel of an arsenite pump. Belongs to the ArsB family gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00342 BL14DL4_00343 BL14DL4_00343 BL14DL4_00343 275879 276226 - HTH-type transcriptional repressor AseR Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00343 BL14DL4_00344 BL14DL4_00344 BL14DL4_00344 276715 277308 - uncharacterized protein gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00344 BL14DL4_00345 BL14DL4_00345 BL14DL4_00345 277430 278155 + hypothetical protein gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00345 BL14DL4_00346 BL14DL4_00346 BL14DL4_00346 278378 279235 - putative glucose uptake protein Involved in the uptake of glucose%3B Belongs to the GRP transporter (TC 2. A. 7. 5) family gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00346 BL14DL4_00347 BL14DL4_00347 amiA amiA 279357 280544 - N-acetylmuramoyl-L-alanine amidase Belongs to the UPF0748 family%3B KEGG: esr:ES1_16340 N-acetylmuramoyl-L-alanine amidase gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00347 BL14DL4_00348 BL14DL4_00348 BL14DL4_00348 280643 281845 - Oligoribonuclease NrnB Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00348 BL14DL4_00349 BL14DL4_00349 pflA pflA 282000 282758 - [Formate-C-acetyltransferase]-activating enzyme Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical%2C using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. Belongs to the organic radical-activating enzymes family%3B KEGG: bli:BL01864 pyruvate formate lyase activating enzyme gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00349 BL14DL4_00350 BL14DL4_00350 pflD pflD 282816 285041 - Formate C-acetyltransferase Contains 1 glycine radical domain%3B Contains 1 PFL domain%3B KEGG: bli:BL01863 formate C-acetyltransferase gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00350 BL14DL4_00351 BL14DL4_00351 dacB dacB 285539 287767 - D-alanyl-D-alanine carboxypeptidase DacC Catalyzes DD-carboxypeptidase and transpeptidation reactions%3B Belongs to the peptidase S13 family%3B KEGG: bld:BLi02133 D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4)%3B Serine-type D-Ala-D-Ala carboxypeptidase gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00351 BL14DL4_00352 BL14DL4_00352 BL14DL4_00352 287849 289027 - NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU12290 NADH dehydrogenase gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00352 BL14DL4_00353 BL14DL4_00353 BL14DL4_00353 289064 289498 - uncharacterized protein gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00353 BL14DL4_00354 BL14DL4_00354 BL14DL4_00354 289450 289773 - hypothetical protein gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00354 BL14DL4_00355 BL14DL4_00355 BL14DL4_00355 289908 290138 - Glucose-6-phosphate isomerase KEGG: bbe:BBR47_08920 glucose-6-phosphate isomerase gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00355 BL14DL4_00356 BL14DL4_00356 BL14DL4_00356 290231 290455 + uncharacterized protein gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00356 BL14DL4_00357 BL14DL4_00357 acsS acsS 290537 292489 - Acetate--CoA ligase Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01993 acetyl-CoA synthetase gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00357 BL14DL4_00358 BL14DL4_00358 pccB pccB 292520 294049 - Propionyl-CoA carboxylase Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: obt:OPIT5_14445 propionyl-CoA carboxylase beta chain gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00358 BL14DL4_00359 BL14DL4_00359 BL14DL4_00359 294070 294852 - Enoyl-CoA hydratase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: lan:Lacal_1125 enoyl-CoA hydratase gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00359 BL14DL4_00360 BL14DL4_00360 hmgL hmgL 294872 295783 - Hydroxymethylglutaryl-CoA lyase Involved in the catabolism of branched amino acids such as leucine%3B Belongs to the HMG-CoA lyase family%3B KEGG: bli:BL01990 hydroxymethylglutaryl-CoA lyase gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00360 BL14DL4_00361 BL14DL4_00361 BL14DL4_00361 295801 296013 - Biotin/lipoyl attachment protein Contains 1 biotinyl-binding domain gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00361 BL14DL4_00362 BL14DL4_00362 accC accC 296031 297371 - Acetyl-CoA carboxylase Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00362 BL14DL4_00363 BL14DL4_00363 BL14DL4_00363 297414 299051 - Putative acyl-CoA synthetase YngI Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01987 fatty-acyl-CoA synthase%3B Acid--thiol ligases gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00363 BL14DL4_00364 BL14DL4_00364 BL14DL4_00364 299083 300243 - Short-chain acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: oih:OB1695 butyryl-CoA dehydrogenase gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00364 BL14DL4_00365 BL14DL4_00365 nqo1 nqo1 300474 301034 + NAD(P)H dehydrogenase (quinone) Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity%2C but this enzymatic activity is not required for activation of KefC%3B Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily%3B KEGG: cvi:CV_0290 NAD(P)H dehydrogenase (quinone) gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00365 BL14DL4_00366 BL14DL4_00366 BL14DL4_00366 301076 301426 - putative HTH-type transcriptional regulator Contains 1 HTH hxlR-type DNA-binding domain gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00366 BL14DL4_00367 BL14DL4_00367 proA proA 301638 302909 - Glutamate-5-semialdehyde dehydrogenase Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bli:BL01984 glutamate-5-semialdehyde dehydrogenase gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00367 BL14DL4_00368 BL14DL4_00368 proB proB 302935 304056 - Glutamate 5-kinase Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: bli:BL01983 glutamate 5-kinase gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00368 BL14DL4_00369 BL14DL4_00369 proC proC 304095 304895 - Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU18480 pyrroline-5-carboxylate reductase gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00369 BL14DL4_00370 BL14DL4_00370 BL14DL4_00370 305143 305346 - hypothetical protein gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00370 BL14DL4_00371 BL14DL4_00371 BL14DL4_00371 305297 305974 - UPF0702 transmembrane protein YetF Belongs to the UPF0702 family gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00371 BL14DL4_00372 BL14DL4_00372 BL14DL4_00372 306344 307480 - Sulfate permease CysP Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00372 BL14DL4_00373 BL14DL4_00373 cysH cysH 307495 308205 - Phosphoadenylyl-sulfate reductase (thioredoxin) Reduction of activated sulfate into sulfite%3B Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bli:BL01979 phosphoadenosine phosphosulfate reductase gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00373 BL14DL4_00374 BL14DL4_00374 comA comA 308753 309517 + Phosphosulfolactate synthase Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL)%3B Belongs to the phosphosulfolactate synthase family%3B KEGG: bli:BL02005 phosphosulfolactate synthase gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00374 BL14DL4_00375 BL14DL4_00375 BL14DL4_00375 309536 310159 - UPF0750 membrane protein YitE Belongs to the UPF0750 family gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00375 BL14DL4_00376 BL14DL4_00376 BL14DL4_00376 310253 311359 - Putative isomerase YitF Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: bss:BSUW23_05560 D-galactarolactone cycloisomerase%3B Intramolecular lyases gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00376 BL14DL4_00377 BL14DL4_00377 BL14DL4_00377 311376 312620 - putative MFS-type transporter YitG Belongs to the major facilitator superfamily gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00377 BL14DL4_00378 BL14DL4_00378 dpm1 dpm1 312692 313699 - Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: fco:FCOL_06185 dolichol-phosphate mannosyltransferase gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00378 BL14DL4_00379 BL14DL4_00379 BL14DL4_00379 313722 315437 - putative membrane protein YkoS gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00379 BL14DL4_00380 BL14DL4_00380 BL14DL4_00380 315563 315748 - hypothetical protein gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00380 BL14DL4_00381 BL14DL4_00381 gltD gltD 315971 317452 - Glutamate synthase (NADPH) Belongs to the glutamate synthase family%3B KEGG: rso:RSc2964 glutamate synthase (NADPH/NADH) small chain gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00381 BL14DL4_00382 BL14DL4_00382 gltB gltB 317469 322034 - Glutamate synthase (NADPH) Belongs to the glutamate synthase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU18450 glutamate synthase (NADPH/NADH) large chain gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00382 BL14DL4_00383 BL14DL4_00383 BL14DL4_00383 322183 323085 + HTH-type transcriptional regulator BsdA Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00383 BL14DL4_00384 BL14DL4_00384 BL14DL4_00384 323223 323435 + hypothetical protein gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00384 BL14DL4_00385 BL14DL4_00385 BL14DL4_00385 323491 325416 - hypothetical protein gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00385 BL14DL4_00386 BL14DL4_00386 BL14DL4_00386 325550 327124 + hypothetical protein gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00386 BL14DL4_00387 BL14DL4_00387 BL14DL4_00387 327264 327737 + hypothetical protein gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00387 BL14DL4_00388 BL14DL4_00388 BL14DL4_00388 327734 329461 + Putative export ATP-binding/permease protein Part of an ABC transporter complex. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00388 BL14DL4_00389 BL14DL4_00389 BL14DL4_00389 329458 331281 + Lipid A export ATP-binding/permease protein MsbA Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00389 BL14DL4_00390 BL14DL4_00390 cypX cypX 331515 332729 + Pulcherriminic acid synthase Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds%2C including steroids%2C fatty acids%2C and xenobiotics. Belongs to the cytochrome P450 family%3B KEGG: pao:Pat9b_5697 pulcherriminic acid synthase gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00390 BL14DL4_00391 BL14DL4_00391 idnO idnO 332778 333494 - Gluconate 5-dehydrogenase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: smw:SMWW4_v1c33960 gluconate 5-dehydrogenase gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00391 BL14DL4_00392 BL14DL4_00392 ppsA ppsA 333881 336475 + Pyruvate%2C water dikinase Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bli:BL01998 pyruvate%2C water dikinase gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00392 BL14DL4_00393 BL14DL4_00393 BL14DL4_00393 336899 338374 + putative MFS-type transporter YvkA Belongs to the major facilitator superfamily. TCR/Tet family gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00393 BL14DL4_00394 BL14DL4_00394 napA napA 338522 340561 + Nitrate reductase Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: ccc:G157_05015 periplasmic nitrate reductase NapA gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00394 BL14DL4_00395 BL14DL4_00395 BL14DL4_00395 340601 341077 - HTH-type transcriptional regulator MhqR Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00395 BL14DL4_00396 BL14DL4_00396 BL14DL4_00396 341216 342737 + Multidrug resistance protein%3B nonfunctional due to frameshift pseudo gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00396 BL14DL4_00397 BL14DL4_00397 BL14DL4_00397 342742 343839 - Spore germination protein YndE Involved in the germinative response to L-alanine. Could be an amino acid transporter (By similarity)%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00397 BL14DL4_00398 BL14DL4_00398 BL14DL4_00398 343879 345075 - Spore germination protein YndF May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00398 BL14DL4_00399 BL14DL4_00399 BL14DL4_00399 345062 346162 - Spore germination protein A2 Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00399 BL14DL4_00400 BL14DL4_00400 BL14DL4_00400 346190 347290 - Spore germination protein A2 Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00400 BL14DL4_00401 BL14DL4_00401 BL14DL4_00401 347313 348881 - putative membrane protein YndD Belongs to the GerABKA family gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00401 BL14DL4_00402 BL14DL4_00402 znuC znuC 349158 350885 - Aliphatic sulfonates import ATP-binding protein SsuB Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain%3B KEGG: xbo:XBJ1_2227 zinc transport system ATP-binding protein%3B Acting on acid gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00402 BL14DL4_00403 BL14DL4_00403 BL14DL4_00403 351339 353324 + Methyl-accepting chemotaxis protein McpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00403 BL14DL4_00404 BL14DL4_00404 BL14DL4_00404 353370 353702 - Protein CsaA Could serves as a molecular chaperone for exported proteins or alternatively acts by stabilizing the SecA protein. Contains 1 tRNA-binding domain gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00404 BL14DL4_00405 BL14DL4_00405 aprX aprX 353925 355253 + Serine protease AprX Displays serine protease activity. Seems to have a broad substrate specificity%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL00903 serine protease AprX%3B Serine endopeptidases gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00405 BL14DL4_00406 BL14DL4_00406 BL14DL4_00406 355305 355715 - uncharacterized protein gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00406 BL14DL4_00407 BL14DL4_00407 BL14DL4_00407 355722 356321 - hypothetical protein gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00407 BL14DL4_00408 BL14DL4_00408 BL14DL4_00408 356458 356949 - putative HTH-type transcriptional regulator YvmB Involved in protein secretion. Contains 1 HTH marR-type DNA-binding domain gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00408 BL14DL4_00409 BL14DL4_00409 nadD nadD 357093 357524 + Nicotinate-nucleotide adenylyltransferase KEGG: bfi:CIY_18840 nicotinate-nucleotide adenylyltransferase gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00409 BL14DL4_00410 BL14DL4_00410 BL14DL4_00410 357771 358256 - hypothetical protein gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00410 BL14DL4_00411 BL14DL4_00411 BL14DL4_00411 358287 359933 - putative membrane protein YndJ gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00411 BL14DL4_00412 BL14DL4_00412 BL14DL4_00412 359930 360547 - uncharacterized protein gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00412 BL14DL4_00413 BL14DL4_00413 BL14DL4_00413 360549 361448 - putative membrane protein YndG gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00413 BL14DL4_00414 BL14DL4_00414 BL14DL4_00414 361691 362263 - putative HTH-type transcriptional regulator YobS Contains 1 HTH tetR-type DNA-binding domain gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00414 BL14DL4_00415 BL14DL4_00415 BL14DL4_00415 362271 362804 - uncharacterized protein Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00415 BL14DL4_00416 BL14DL4_00416 BL14DL4_00416 363066 363539 - Putative transcriptional regulator protein YobU gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00416 BL14DL4_00417 BL14DL4_00417 BL14DL4_00417 363536 363817 - hypothetical protein gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00417 BL14DL4_00418 BL14DL4_00418 BL14DL4_00418 363871 364806 - putative HTH-type transcriptional regulator YobV Contains 1 HTH deoR-type DNA-binding domain gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00418 BL14DL4_00419 BL14DL4_00419 BL14DL4_00419 365010 365507 + Protein csk22 gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00419 BL14DL4_00420 BL14DL4_00420 BL14DL4_00420 365546 365878 - HTH-type transcriptional repressor CzrA Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA%3B Contains 1 HTH arsR-type DNA-binding domain gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00420 BL14DL4_00421 BL14DL4_00421 BL14DL4_00421 365954 366778 - uncharacterized protein gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00421 BL14DL4_00422 BL14DL4_00422 BL14DL4_00422 366943 367185 - uncharacterized protein gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00422 BL14DL4_00423 BL14DL4_00423 BL14DL4_00423 367338 368675 + Low-affinity putrescine importer PlaP Putrescine importer%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00423 BL14DL4_00424 BL14DL4_00424 BL14DL4_00424 368810 369418 + putative membrane protein YocA gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00424 BL14DL4_00425 BL14DL4_00425 capD capD 369552 370538 - UDP-glucose 4-epimerase Belongs to the polysaccharide synthase family%3B KEGG: yfr:AW19_2183 UDP-glucose 4-epimerase gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00425 BL14DL4_00426 BL14DL4_00426 BL14DL4_00426 370591 371229 - hypothetical protein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00426 BL14DL4_00427 BL14DL4_00427 BL14DL4_00427 371426 371839 - hypothetical protein gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00427 BL14DL4_00428 BL14DL4_00428 waaG waaG 371854 373062 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: cko:CKO_05089 UDP-glucose:(heptosyl)LPS alpha-1%2C3-glucosyltransferase%3B Hexosyltransferases gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00428 BL14DL4_00429 BL14DL4_00429 BL14DL4_00429 373224 373757 - putative membrane protein YozB gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00429 BL14DL4_00430 BL14DL4_00430 BL14DL4_00430 373910 374890 - hypothetical protein gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00430 BL14DL4_00431 BL14DL4_00431 BL14DL4_00431 375120 375629 + uncharacterized protein gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00431 BL14DL4_00432 BL14DL4_00432 BL14DL4_00432 375702 377291 - Putative uncharacterized symporter Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00432 BL14DL4_00433 BL14DL4_00433 lytE lytE 377450 378256 - Cell wall-binding protein YocH Contains 2 LysM repeats%3B KEGG: gwc:GWCH70_1211 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00433 BL14DL4_00434 BL14DL4_00434 recQ recQ 378492 380297 - DNA helicase Probable DNA helicase. Required for DNA repair and intramolecular recombinatio%3B probably has overlapping function with RecS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 HRDC domain%3B KEGG: bli:BL01304 ATP-dependent DNA helicase RecQ gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00434 BL14DL4_00435 BL14DL4_00435 BL14DL4_00435 380436 380954 - uncharacterized protein gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00435 BL14DL4_00436 BL14DL4_00436 BL14DL4_00436 381030 381191 + hypothetical protein gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00436 BL14DL4_00437 BL14DL4_00437 BL14DL4_00437 381431 381607 + uncharacterized protein gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00437 BL14DL4_00438 BL14DL4_00438 BL14DL4_00438 381733 381806 + tRNA-Arg tRNA gene437 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00438 BL14DL4_00439 BL14DL4_00439 BL14DL4_00439 382121 382333 - uncharacterized protein gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00439 BL14DL4_00440 BL14DL4_00440 BL14DL4_00440 383239 384204 - hypothetical protein gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00440 BL14DL4_00441 BL14DL4_00441 BL14DL4_00441 384514 385074 - uncharacterized protein gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00441 BL14DL4_00442 BL14DL4_00442 fdoG fdoG 385067 388210 - Formate dehydrogenase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bld:BLi02222 formate dehydrogenase major subunit gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00442 BL14DL4_00443 BL14DL4_00443 BL14DL4_00443 388625 388870 - hypothetical protein gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00443 BL14DL4_00444 BL14DL4_00444 BL14DL4_00444 389357 389653 - hypothetical protein gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00444 BL14DL4_00445 BL14DL4_00445 BL14DL4_00445 389927 390592 - uncharacterized protein Contains 1 PilZ domain gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00445 BL14DL4_00446 BL14DL4_00446 BL14DL4_00446 390841 391023 - hypothetical protein gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00446 BL14DL4_00447 BL14DL4_00447 BL14DL4_00447 391185 391310 - hypothetical protein gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00447 BL14DL4_00448 BL14DL4_00448 BL14DL4_00448 391322 391600 - uncharacterized protein gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00448 BL14DL4_00449 BL14DL4_00449 BL14DL4_00449 391656 392000 - uncharacterized protein gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00449 BL14DL4_00450 BL14DL4_00450 BL14DL4_00450 392648 392926 + hypothetical protein gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00450 BL14DL4_00451 BL14DL4_00451 BL14DL4_00451 393388 393675 + uncharacterized protein gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00451 BL14DL4_00452 BL14DL4_00452 BL14DL4_00452 393965 395167 - Spore germination protein YndF May be involved in spore germination%3B Belongs to the GerABKC lipoprotein family gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00452 BL14DL4_00453 BL14DL4_00453 BL14DL4_00453 395407 395874 + uncharacterized protein gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00453 BL14DL4_00454 BL14DL4_00454 BL14DL4_00454 395908 396750 + hypothetical protein gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00454 BL14DL4_00455 BL14DL4_00455 mtaD mtaD 396937 398286 - S-methyl-5'-thioadenosine deaminase Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine%2C whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine%2C S-adenosyl-L-homocysteine and adenosine to a small extent%3B Belongs to the MTA/SAH deaminase family%3B KEGG: mac:MA1276 5-methylthioadenosine/S-adenosylhomocysteine deaminase gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00455 BL14DL4_00456 BL14DL4_00456 BL14DL4_00456 398559 398807 - Spore coat protein gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00456 BL14DL4_00457 BL14DL4_00457 BL14DL4_00457 399043 399252 - hypothetical protein gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00457 BL14DL4_00458 BL14DL4_00458 BL14DL4_00458 399458 400240 - Chloride peroxidase May be a chlorinating enzyme involved in 7- chlorotetracycline biosynthesis. Able to brominate as well%3B Belongs to the bacterial non-heme bromo- and chloro- peroxidases family%3B KEGG: bld:BLi02236 non-heme chloroperoxidase gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00458 BL14DL4_00459 BL14DL4_00459 BL14DL4_00459 400376 400867 + SPBc2 prophage-derived uncharacterized protein YoqH gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00459 BL14DL4_00460 BL14DL4_00460 BL14DL4_00460 400945 401181 - Spore coat protein gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00460 BL14DL4_00461 BL14DL4_00461 BL14DL4_00461 401355 401978 + Homoserine/homoserine lactone efflux protein Conducts the efflux of homoserine and homoserine lactone%3B Belongs to the rht family gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00461 BL14DL4_00462 BL14DL4_00462 BL14DL4_00462 402719 402904 + 30S ribosomal protein S14 type Z Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00462 BL14DL4_00463 BL14DL4_00463 mutT mutT 402988 403461 - 8-oxo-dGTP diphosphatase KEGG: pod:PODO_15870 8-oxo-dGTP diphosphatase gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00463 BL14DL4_00464 BL14DL4_00464 BL14DL4_00464 403654 406320 - Pyruvate%2C water dikinase Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bli:BL05212 pyruvate%2C water dikinase gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00464 BL14DL4_00465 BL14DL4_00465 BL14DL4_00465 406593 407198 + putative HTH-type transcriptional regulator YxbF Contains 2 HTH tetR-type DNA-binding domains gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00465 BL14DL4_00466 BL14DL4_00466 BL14DL4_00466 407300 407425 + hypothetical protein gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00466 BL14DL4_00467 BL14DL4_00467 BL14DL4_00467 407447 407911 + uncharacterized protein gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00467 BL14DL4_00468 BL14DL4_00468 BL14DL4_00468 408032 408547 + uncharacterized protein Belongs to the DinB family gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00468 BL14DL4_00469 BL14DL4_00469 acpD acpD 408591 409217 - FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bli:BL01874 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00469 BL14DL4_00470 BL14DL4_00470 BL14DL4_00470 409337 409825 - General stress protein 16O Contains 1 dksA C4-type zinc finger gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00470 BL14DL4_00471 BL14DL4_00471 BL14DL4_00471 409939 410283 - uncharacterized protein gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00471 BL14DL4_00472 BL14DL4_00472 BL14DL4_00472 410684 410893 - uncharacterized protein gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00472 BL14DL4_00473 BL14DL4_00473 feaB feaB 411153 412649 + Phenylacetaldehyde dehydrogenase Belongs to the aldehyde dehydrogenase family%3B KEGG: bld:BLi02249 phenylacetaldehyde dehydrogenase gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00473 BL14DL4_00474 BL14DL4_00474 BL14DL4_00474 412740 414020 + putative MFS-type transporter YjbB Belongs to the major facilitator superfamily gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00474 BL14DL4_00475 BL14DL4_00475 BL14DL4_00475 414206 414742 - Ribosomal-protein-alanine N-acetyltransferase This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC0964 ribosomal-protein-alanine N-acetyltransferase gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00475 BL14DL4_00476 BL14DL4_00476 BL14DL4_00476 414760 415161 - Cytidine deaminase KEGG: psf:PSE_1583 cytidine deaminase gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00476 BL14DL4_00477 BL14DL4_00477 sqhC sqhC 415432 417321 + Sporulenol synthase Catalyzes the cyclization of tetraprenyl beta-curcumene into sporulenol%3B Belongs to the terpene cyclase/mutase family%3B Contains 3 PFTB repeats%3B KEGG: bli:BL00583 sporulenol synthase gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00477 BL14DL4_00478 BL14DL4_00478 sod2 sod2 417318 418163 + Superoxide dismutase Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems%3B Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bli:BL00582 superoxide dismutase%2C Fe-Mn family gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00478 BL14DL4_00479 BL14DL4_00479 BL14DL4_00479 418771 419301 + Stress response protein YvgO gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00479 BL14DL4_0048 BL14DL4_0048 BL14DL4_0048 41692 41925 - hypothetical protein gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0048 BL14DL4_00480 BL14DL4_00480 BL14DL4_00480 419526 420866 - putative sodium-dependent transporter Putative sodium-dependent transporter. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00480 BL14DL4_00481 BL14DL4_00481 BL14DL4_00481 421081 422061 + putative sodium-dependent transporter YocS Belongs to the bile acid:sodium symporter (BASS) (TC 2. A. 28) family gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00481 BL14DL4_00482 BL14DL4_00482 dlsT dlsT 422091 423371 - Dihydrolipoyllysine-residue succinyltransferase The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: cvi:CV_1072 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00482 BL14DL4_00483 BL14DL4_00483 ogdH ogdH 423386 426220 - Oxoglutarate dehydrogenase (succinyl-transferring) The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)%3B Belongs to the alpha-ketoglutarate dehydrogenase family%3B KEGG: bsu:BSU19370 2-oxoglutarate dehydrogenase E1 component gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00483 BL14DL4_00484 BL14DL4_00484 BL14DL4_00484 426606 428519 - uncharacterized protein Contains 1 VWFA domain gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00484 BL14DL4_00485 BL14DL4_00485 BL14DL4_00485 428529 429419 - uncharacterized protein Belongs to the CbbQ/NirQ/NorQ/GpvN family gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00485 BL14DL4_00486 BL14DL4_00486 sod1 sod1 429514 430107 - Superoxide dismutase Belongs to the Cu-Zn superoxide dismutase family%3B KEGG: bli:BL01449 superoxide dismutase%2C Cu-Zn family gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00486 BL14DL4_00487 BL14DL4_00487 lytF lytF 430217 431524 - D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS Probably functions as a cell separation enzyme in addition to LytE and LytF%3B Belongs to the peptidase C40 family%3B Contains 4 LysM repeats%3B KEGG: bsu:BSU09370 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00487 BL14DL4_00488 BL14DL4_00488 BL14DL4_00488 432656 434014 + putative multidrug resistance protein NorM Multidrug efflux pump%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00488 BL14DL4_00489 BL14DL4_00489 BL14DL4_00489 434058 434723 - putative N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal). Has weak activity compared with bshB1%3B Belongs to the PIGL family gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00489 BL14DL4_0049 BL14DL4_0049 BL14DL4_0049 41939 43714 - hypothetical protein gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0049 BL14DL4_00490 BL14DL4_00490 BL14DL4_00490 434741 435091 - uncharacterized protein gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00490 BL14DL4_00491 BL14DL4_00491 BL14DL4_00491 435093 435368 - uncharacterized protein gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00491 BL14DL4_00492 BL14DL4_00492 BL14DL4_00492 435443 436375 - putative transporter YojE Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00492 BL14DL4_00493 BL14DL4_00493 BL14DL4_00493 436458 436910 + Spore germination protein GerT Involved in spore germination gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00493 BL14DL4_00494 BL14DL4_00494 BL14DL4_00494 436863 436958 - hypothetical protein gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00494 BL14DL4_00495 BL14DL4_00495 BL14DL4_00495 437139 437837 + Cellulase May promote colonization of plant roots. May cause loosening and extension of plant cell walls by disrupting non- covalent bonding between cellulose microfibrils and matrix glucans. Has very low expansin activity (in vitro). No enzymatic activity has been found. Binds to peptidoglycan and to plant cell walls%3B Contains 1 expansin-like EG45 domain%3B KEGG: cmi:pCM1_0020 endoglucanase gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00495 BL14DL4_00496 BL14DL4_00496 BL14DL4_00496 437949 438227 - uncharacterized protein gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00496 BL14DL4_00497 BL14DL4_00497 BL14DL4_00497 438827 438896 + Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00497 BL14DL4_00498 BL14DL4_00498 BL14DL4_00498 439045 439365 - HTH-type transcriptional regulator YodB Negatively regulates yodC and azoR1 which may contribute to the degradation of aromatic compounds. Probably positively regulates the catechol-specific transcription of mhqNOP%2C mhqED%2C and mhqA%3B Contains 1 HTH hxlR-type DNA-binding domain gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00498 BL14DL4_00499 BL14DL4_00499 BL14DL4_00499 439500 440120 + Putative NAD(P)H nitroreductase YdgI Belongs to the nitroreductase family%3B KEGG: hap:HAPS_2135 null%3B Oxidoreductases gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00499 BL14DL4_0050 BL14DL4_0050 BL14DL4_0050 43692 43940 - hypothetical protein gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0050 BL14DL4_00500 BL14DL4_00500 BL14DL4_00500 440165 440770 - Putative hydrolase Putative hydrolase that may contribute to the degradation of aromatic compounds%3B Belongs to the AB hydrolase superfamily. AB hydrolase 2 family gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00500 BL14DL4_00501 BL14DL4_00501 BL14DL4_00501 441135 441338 + putative membrane protein YoyD gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00501 BL14DL4_00502 BL14DL4_00502 BL14DL4_00502 441338 442819 + putative symporter YodF Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00502 BL14DL4_00503 BL14DL4_00503 ctpA ctpA 442864 444261 - C-terminal processing peptidase Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL01439 carboxyl-terminal processing protease gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00503 BL14DL4_00504 BL14DL4_00504 BL14DL4_00504 444421 445131 + putative methyltransferase YodH Belongs to the methyltransferase superfamily gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00504 BL14DL4_00505 BL14DL4_00505 BL14DL4_00505 445226 445480 + uncharacterized protein gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00505 BL14DL4_00506 BL14DL4_00506 vanY vanY 445516 446337 - Serine-type D-Ala-D-Ala carboxypeptidase Belongs to the peptidase M15B family%3B KEGG: bli:BL01438 D-alanyl-D-alanine carboxypeptidase gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00506 BL14DL4_00507 BL14DL4_00507 deoD deoD 446371 447069 - Purine-nucleoside phosphorylase Belongs to the PNP/UDP phosphorylase family%3B KEGG: shp:Sput200_1676 purine-nucleoside phosphorylase gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00507 BL14DL4_00508 BL14DL4_00508 BL14DL4_00508 447279 448286 + UPF0718 protein YcgR Belongs to the UPF0718 family gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00508 BL14DL4_00509 BL14DL4_00509 BL14DL4_00509 448303 449175 + hypothetical protein gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00509 BL14DL4_0051 BL14DL4_0051 BL14DL4_0051 44102 44335 + DNA (cytosine-5-)-methyltransferase KEGG: rto:RTO_14860 DNA (cytosine-5)-methyltransferase 1 gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0051 BL14DL4_00510 BL14DL4_00510 BL14DL4_00510 449243 449377 + uncharacterized protein gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00510 BL14DL4_00511 BL14DL4_00511 BL14DL4_00511 449415 449735 - uncharacterized protein gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00511 BL14DL4_00512 BL14DL4_00512 bcrC bcrC 449790 450509 - Undecaprenyl-diphosphate phosphatase Belongs to the PA-phosphatase related phosphoesterase family%3B KEGG: lsa:LSA1438 undecaprenyl-diphosphatase gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00512 BL14DL4_00513 BL14DL4_00513 BL14DL4_00513 450512 450682 - uncharacterized protein gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00513 BL14DL4_00514 BL14DL4_00514 BL14DL4_00514 450805 450939 + putative membrane protein YoyF gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00514 BL14DL4_00515 BL14DL4_00515 BL14DL4_00515 450932 451612 - uncharacterized protein gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00515 BL14DL4_00516 BL14DL4_00516 BL14DL4_00516 451775 451996 - UPF0346 protein Belongs to the UPF0346 family gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00516 BL14DL4_00517 BL14DL4_00517 BL14DL4_00517 452102 452383 - uncharacterized protein gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00517 BL14DL4_00518 BL14DL4_00518 kamA kamA 452380 453789 - Lysine 2%2C3-aminomutase Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine%3B Belongs to the radical SAM superfamily. KamA family%3B KEGG: bli:BL01430 lysine 2%2C3-aminomutase gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00518 BL14DL4_00519 BL14DL4_00519 BL14DL4_00519 453888 454721 - Lysine 2%2C3-aminomutase In vitro%2C is able to catalyze the acetylation of beta- lysine to N6-acetyl-beta-lysine%2C an archaeal osmolyte produced by methanogenic archaea. Its physiological function has not yet been elucidated%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: det:DET0221 lysine 2%2C3-aminomutase gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00519 BL14DL4_0052 BL14DL4_0052 BL14DL4_0052 44345 45040 - Immunity protein gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0052 BL14DL4_00520 BL14DL4_00520 argE argE 454750 456018 - Acetylornithine deacetylase Belongs to the peptidase M20A family%3B KEGG: bsu:BSU19710 acetylornithine deacetylase gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00520 BL14DL4_00521 BL14DL4_00521 scoB scoB 456032 456685 - 3-oxoacid CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit B family%3B KEGG: samy:DB32_004337 3-oxoacid CoA-transferase subunit B gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00521 BL14DL4_00522 BL14DL4_00522 atoD atoD 456667 457359 - Acetate CoA-transferase Belongs to the 3-oxoacid CoA-transferase subunit A family%3B KEGG: bli:BL01426 acetate CoA/acetoacetate CoA-transferase alpha subunit gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00522 BL14DL4_00523 BL14DL4_00523 bioA bioA 457356 458696 - Adenosylmethionine--8-amino-7-oxononanoate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: rma:Rmag_0118 adenosylmethionine---8-amino-7-oxononanoate aminotransferase gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00523 BL14DL4_00524 BL14DL4_00524 BL14DL4_00524 458863 460098 - hypothetical protein gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00524 BL14DL4_00525 BL14DL4_00525 BL14DL4_00525 460447 461217 - putative N-acetyltransferase CgeE May be involved in maturation of the outermost layer of the spore. Contains 1 N-acetyltransferase domain gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00525 BL14DL4_00526 BL14DL4_00526 msrB msrB 461335 461790 - Peptide-methionine (R)-S-oxide reductase Belongs to the MsrB Met sulfoxide reductase family%3B KEGG: bst:GYO_2391 peptide-methionine (R)-S-oxide reductase gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00526 BL14DL4_00527 BL14DL4_00527 msrA msrA 461777 462322 - Peptide-methionine (S)-S-oxide reductase Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine%3B Belongs to the MsrA Met sulfoxide reductase family%3B KEGG: bsu:BSU21690 peptide-methionine (S)-S-oxide reductase gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00527 BL14DL4_00528 BL14DL4_00528 BL14DL4_00528 462697 463131 + putative HTH-type transcriptional regulator YpoP Contains 1 HTH marR-type DNA-binding domain gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00528 BL14DL4_00529 BL14DL4_00529 BL14DL4_00529 463197 463448 + hypothetical protein gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00529 BL14DL4_0053 BL14DL4_0053 BL14DL4_0053 45138 45302 - hypothetical protein gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0053 BL14DL4_00530 BL14DL4_00530 dge1 dge1 463509 464597 - Diguanylate cyclase Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B KEGG: bli:BL05221 diguanylate cyclase gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00530 BL14DL4_00531 BL14DL4_00531 BL14DL4_00531 464731 466062 - putative multidrug resistance protein YpnP Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00531 BL14DL4_00532 BL14DL4_00532 BL14DL4_00532 466158 466862 + hypothetical protein gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00532 BL14DL4_00533 BL14DL4_00533 BL14DL4_00533 466959 467159 - uncharacterized protein gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00533 BL14DL4_00534 BL14DL4_00534 BL14DL4_00534 467191 467763 - uncharacterized protein gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00534 BL14DL4_00535 BL14DL4_00535 BL14DL4_00535 467774 468526 - uncharacterized protein gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00535 BL14DL4_00536 BL14DL4_00536 BL14DL4_00536 468669 469271 - SCO1 protein like protein Neccessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling%3B Belongs to the SCO1/2 family%3B Contains 1 thioredoxin domain gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00536 BL14DL4_00537 BL14DL4_00537 BL14DL4_00537 469268 470110 - DegV domain-containing protein May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00537 BL14DL4_00538 BL14DL4_00538 BL14DL4_00538 470258 470509 - uncharacterized protein gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00538 BL14DL4_00539 BL14DL4_00539 ilvA ilvA 470602 471870 - Threonine ammonia-lyase Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate)%2C which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell%2C the second step is accelerated by RidA (By similarity)%3B Belongs to the serine/threonine dehydratase family%3B Contains 1 ACT-like domain%3B KEGG: bsu:BSU21770 threonine dehydratase gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00539 BL14DL4_0054 BL14DL4_0054 BL14DL4_0054 45364 46104 + hypothetical protein gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0054 BL14DL4_00540 BL14DL4_00540 BL14DL4_00540 472104 473105 + Psp operon transcriptional activator Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene%3B Contains 1 sigma-54 factor interaction domain gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00540 BL14DL4_00541 BL14DL4_00541 BL14DL4_00541 473121 473762 + Hemolysin-3 like protein Belongs to the UPF0073 (Hly-III) family gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00541 BL14DL4_00542 BL14DL4_00542 plsC plsC 473803 474426 - 1-acylglycerol-3-phosphate O-acyltransferase KEGG: bss:BSUW23_10665 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00542 BL14DL4_00543 BL14DL4_00543 folA folA 474441 474929 - Dihydrofolate reductase Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis%2C and for DNA precursor synthesis (By similarity)%3B Belongs to the dihydrofolate reductase family%3B Contains 1 DHFR (dihydrofolate reductase) domain%3B KEGG: eco:b0048 dihydrofolate reductase gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00543 BL14DL4_00544 BL14DL4_00544 pgpA pgpA 475285 475833 - Phosphatidylglycerophosphatase To B. subtilis YutG%3B KEGG: bpu:BPUM_1917 phosphatidylglycerophosphatase A gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00544 BL14DL4_00545 BL14DL4_00545 BL14DL4_00545 475849 476451 - uncharacterized protein gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00545 BL14DL4_00546 BL14DL4_00546 BL14DL4_00546 476723 477493 - uncharacterized protein gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00546 BL14DL4_00547 BL14DL4_00547 BL14DL4_00547 477530 477964 - UPF0403 protein Belongs to the UPF0403 family gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00547 BL14DL4_00548 BL14DL4_00548 ilvD ilvD 478056 479732 - Dihydroxy-acid dehydratase Belongs to the IlvD/Edd family%3B KEGG: bli:BL05225 dihydroxy-acid dehydratase gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00548 BL14DL4_00549 BL14DL4_00549 BL14DL4_00549 480062 481198 - uncharacterized protein gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00549 BL14DL4_0055 BL14DL4_0055 BL14DL4_0055 46433 46774 + hypothetical protein gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0055 BL14DL4_00550 BL14DL4_00550 BL14DL4_00550 481229 481900 - uncharacterized protein Contains 1 HD domain gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00550 BL14DL4_00551 BL14DL4_00551 BL14DL4_00551 481888 482367 - Glutathione peroxidase May constitute a glutathione peroxidase-like protective system against oxidative stresses. Involved positively in abscisic acid (ABA) signaling pathway that regulates numerous ABA responses%2C such as stomatal closure%2C seed germination and inhibition of vegetative growth. Oxidizes and represses target proteins (e. g. the phosphatase activity of ABI1 and ABI2) when oxidized by H(2)O(2)%2C probably after ABA signaling. Modulates the calcium channel activity in guard cells in response to ABA or H(2)O(2). Confers tolerance to drought stress%2C by enhancing the ABA-dependent stomatal closure%3B Belongs to the glutathione peroxidase family%3B KEGG: slo:Shew_2741 glutathione peroxidase gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00551 BL14DL4_00552 BL14DL4_00552 BL14DL4_00552 482383 484062 - Formate--tetrahydrofolate ligase Belongs to the formate--tetrahydrofolate ligase family%3B KEGG: bli:BL01370 formate--tetrahydrofolate ligase gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00552 BL14DL4_00553 BL14DL4_00553 metA metA 484214 485122 + Homoserine O-succinyltransferase Belongs to the HTS family%3B KEGG: bli:BL01365 homoserine O-succinyltransferase gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00553 BL14DL4_00554 BL14DL4_00554 ugtP ugtP 485393 486544 + 1%2C2-diacylglycerol 3-glucosyltransferase Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG)%2C thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1%2C2-diacyl- sn-glycerol)%2C beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1%2C2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)%3B Belongs to the glycosyltransferase 28 family. UgtP subfamily%3B KEGG: bsu:BSU21920 processive 1%2C2-diacylglycerol beta-glucosyltransferase gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00554 BL14DL4_00555 BL14DL4_00555 BL14DL4_00555 486594 487283 - hypothetical protein gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00555 BL14DL4_00556 BL14DL4_00556 BL14DL4_00556 487568 487768 + Cold shock protein CspB Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00556 BL14DL4_00557 BL14DL4_00557 BL14DL4_00557 487824 488006 - Regulatory protein DegR Stabilizes the phosphorylated form of DegU%2C leading to enhanced production of levansucrase%2C alkaline protease%2C and neutral protease gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00557 BL14DL4_00558 BL14DL4_00558 BL14DL4_00558 488166 488432 + uncharacterized protein gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00558 BL14DL4_00559 BL14DL4_00559 BL14DL4_00559 488516 488701 - uncharacterized protein gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00559 BL14DL4_0056 BL14DL4_0056 BL14DL4_0056 46876 47340 - hypothetical protein gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0056 BL14DL4_00560 BL14DL4_00560 rnhA rnhA 488716 489375 - Ribonuclease H Contains 1 RNase H domain%3B KEGG: blh:BaLi_c24240 ribonuclease HI gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00560 BL14DL4_00561 BL14DL4_00561 BL14DL4_00561 489451 490152 + uncharacterized protein gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00561 BL14DL4_00562 BL14DL4_00562 BL14DL4_00562 490142 490540 + Ribonuclease H Not know%3B does not have RNase H activity. Belongs to the RNase H family. EbsB subfamily%3B Contains 1 RNase H domain%3B KEGG: bli:BL00670 ribonuclease HI gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00562 BL14DL4_00563 BL14DL4_00563 BL14DL4_00563 490583 490729 + hypothetical protein gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00563 BL14DL4_00564 BL14DL4_00564 dpo1 dpo1 490740 491627 - DNA-directed DNA polymerase 5'-3' exonuclease acting preferentially on double- stranded DNA%3B Contains 1 5'-3' exonuclease domain%3B KEGG: lpl:lp_1508 DNA polymerase I gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00564 BL14DL4_00565 BL14DL4_00565 BL14DL4_00565 491712 491861 - uncharacterized protein gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00565 BL14DL4_00566 BL14DL4_00566 BL14DL4_00566 491941 492210 - uncharacterized protein gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00566 BL14DL4_00567 BL14DL4_00567 BL14DL4_00567 492285 495845 - uncharacterized protein gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00567 BL14DL4_00568 BL14DL4_00568 BL14DL4_00568 496148 496651 - uncharacterized protein gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00568 BL14DL4_00569 BL14DL4_00569 BL14DL4_00569 496659 497756 - Putative chalcone synthase Belongs to the chalcone/stilbene synthases family gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00569 BL14DL4_0057 BL14DL4_0057 BL14DL4_0057 47454 47828 - hypothetical protein gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0057 BL14DL4_00570 BL14DL4_00570 BL14DL4_00570 497798 498349 - Phosphinothricin acetyltransferase KEGG: mve:X875_15470 phosphinothricin acetyltransferase gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00570 BL14DL4_00571 BL14DL4_00571 BL14DL4_00571 498434 499750 - Xanthine permease Transport of xanthine in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00571 BL14DL4_00572 BL14DL4_00572 BL14DL4_00572 499747 500331 - Xanthine phosphoribosyltransferase Converts the preformed base xanthine%2C a product of nucleic acid breakdown%2C to xanthosine 5'-monophosphate (XMP)%2C so it can be reused for RNA or DNA synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily%3B KEGG: bli:BL00680 xanthine phosphoribosyltransferase gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00572 BL14DL4_00573 BL14DL4_00573 BL14DL4_00573 500688 502190 - Carboxypeptidase Taq Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus%2C including neutral%2C aromatic%2C polar and basic residues. Has lower activity with substrates ending with His or Trp%3B Belongs to the peptidase M32 family%3B KEGG: bli:BL00681 carboxypeptidase Taq gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00573 BL14DL4_00574 BL14DL4_00574 dinG dinG 502304 504223 - DNA helicase Belongs to the helicase family. DinG subfamily%3B Contains 1 helicase ATP-binding domain%3B KEGG: bli:BL05232 ATP-dependent DNA helicase DinG gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00574 BL14DL4_00575 BL14DL4_00575 BL14DL4_00575 504332 504508 - hypothetical protein gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00575 BL14DL4_00576 BL14DL4_00576 BL14DL4_00576 504786 505184 + hypothetical protein gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00576 BL14DL4_00577 BL14DL4_00577 ypsC ypsC 505312 506463 - Putative RNA methyltransferase YpsC Belongs to the methyltransferase superfamily%3B Contains 1 THUMP domain%3B KEGG: bli:BL05234 putative N6-adenine-specific DNA methylase%3B Methyltransferases gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00577 BL14DL4_00578 BL14DL4_00578 BL14DL4_00578 506998 507294 - Cell cycle protein GpsB Divisome component that associates with the complex late in its assembly%2C after the Z-ring is formed%2C and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA%2C is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation%3B Belongs to the GpsB family gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00578 BL14DL4_00579 BL14DL4_00579 BL14DL4_00579 507375 507926 - UPF0398 protein Belongs to the UPF0398 family gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00579 BL14DL4_0058 BL14DL4_0058 BL14DL4_0058 47904 48362 - hypothetical protein gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0058 BL14DL4_00580 BL14DL4_00580 BL14DL4_00580 508042 508311 - Spore coat protein gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00580 BL14DL4_00581 BL14DL4_00581 BL14DL4_00581 508396 508491 - hypothetical protein gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00581 BL14DL4_00582 BL14DL4_00582 BL14DL4_00582 508553 509866 - uncharacterized protein gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00582 BL14DL4_00583 BL14DL4_00583 BL14DL4_00583 509872 512148 - DEAD-box ATP-dependent RNA helicase Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00583 BL14DL4_00584 BL14DL4_00584 BL14DL4_00584 512249 512755 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane%3B Contains 1 PTS EIIA type-1 domain%3B KEGG: bsu:BSU22230 PTS system%2C glucose-specific IIA component gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00584 BL14DL4_00585 BL14DL4_00585 BL14DL4_00585 512931 513350 + uncharacterized protein gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00585 BL14DL4_00586 BL14DL4_00586 BL14DL4_00586 513369 513812 - uncharacterized protein gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00586 BL14DL4_00587 BL14DL4_00587 BL14DL4_00587 513983 514192 + uncharacterized protein gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00587 BL14DL4_00588 BL14DL4_00588 BL14DL4_00588 514225 514596 - uncharacterized protein gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00588 BL14DL4_00589 BL14DL4_00589 BL14DL4_00589 514654 514881 - hypothetical protein gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00589 BL14DL4_0059 BL14DL4_0059 BL14DL4_0059 48471 48773 + hypothetical protein gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0059 BL14DL4_00590 BL14DL4_00590 BL14DL4_00590 515081 515185 + hypothetical protein gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00590 BL14DL4_00591 BL14DL4_00591 BL14DL4_00591 515218 516177 - uncharacterized protein gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00591 BL14DL4_00592 BL14DL4_00592 BL14DL4_00592 516231 516827 + Holliday junction resolvase RecU Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands%3B Belongs to the RecU family gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00592 BL14DL4_00593 BL14DL4_00593 mrcA mrcA 516885 519572 + Penicillin-binding protein 1A/1B Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity)%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B Contains 1 fibronectin type-III domain%3B KEGG: bli:BL02732 penicillin-binding protein 1A%3B Hexosyltransferases gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00593 BL14DL4_00594 BL14DL4_00594 BL14DL4_00594 519593 520096 - uncharacterized protein gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00594 BL14DL4_00595 BL14DL4_00595 BL14DL4_00595 520093 520755 - DNA-(apurinic or apyrimidinic site) lyase DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond%2C leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination%2C leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: nsa:Nitsa_1368 endonuclease III gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00595 BL14DL4_00596 BL14DL4_00596 BL14DL4_00596 520772 521470 - DNA replication protein DnaD gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00596 BL14DL4_00597 BL14DL4_00597 narS narS 521545 522837 - Asparagine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU22360 asparaginyl-tRNA synthetase gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00597 BL14DL4_00598 BL14DL4_00598 aspB aspB 522987 524171 - Aspartate transaminase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: woo:wOo_04400 aspartate aminotransferase gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00598 BL14DL4_00599 BL14DL4_00599 BL14DL4_00599 524193 524678 - uncharacterized protein gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00599 BL14DL4_0060 BL14DL4_0060 BL14DL4_0060 48910 49587 - hypothetical protein gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0060 BL14DL4_00600 BL14DL4_00600 BL14DL4_00600 524688 524858 - uncharacterized protein gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00600 BL14DL4_00601 BL14DL4_00601 BL14DL4_00601 525011 527803 - DNA helicase Probable helicase involved in DNA repair and perhaps also replication%3B Belongs to the helicase family. DinG subfamily%3B Contains 1 exonuclease domain%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02749 ATP-dependent DNA helicase DinG gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00601 BL14DL4_00602 BL14DL4_00602 panD panD 527941 528324 - Aspartate 1-decarboxylase Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine%3B Belongs to the PanD family%3B KEGG: bli:BL02750 aspartate 1-decarboxylase gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00602 BL14DL4_00603 BL14DL4_00603 panC panC 528324 529190 - Pantoate--beta-alanine ligase (AMP-forming) Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate%3B Belongs to the pantothenate synthetase family%3B KEGG: bli:BL02751 pantoate--beta-alanine ligase gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00603 BL14DL4_00604 BL14DL4_00604 panB panB 529193 530026 - 3-methyl-2-oxobutanoate hydroxymethyltransferase Catalyzes the reversible reaction in which hydroxymethyl group from 5%2C10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate%3B Belongs to the PanB family%3B KEGG: bli:BL02752 3-methyl-2-oxobutanoate hydroxymethyltransferase gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00604 BL14DL4_00605 BL14DL4_00605 birA birA 530276 531259 - Biotin--[acetyl-CoA-carboxylase] ligase Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor%3B Belongs to the biotin--protein ligase family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bli:BL02753 BirA family transcriptional regulator%2C biotin operon repressor / biotin-(acetyl-CoA-carboxylase) ligase gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00605 BL14DL4_00606 BL14DL4_00606 BL14DL4_00606 531244 532437 - CCA-adding enzyme Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C%2C C%2C and A to the tRNA nucleotide-73%2C using CTP and ATP as substrates and producing inorganic pyrophosphate%3B Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily%3B KEGG: bss:BSUW23_11010 tRNA nucleotidyltransferase (CCA-adding enzyme)%3B CCA tRNA nucleotidyltransferase gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00606 BL14DL4_00607 BL14DL4_00607 BL14DL4_00607 532397 533578 - N-acetyl-alpha-D-glucosaminyl L-malate synthase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway%2C the formation of N- acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate%3B Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: saa:SAUSA300_1349 null%3B Hexosyltransferases gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00607 BL14DL4_00608 BL14DL4_00608 BL14DL4_00608 533578 534315 - N-acetyl-alpha-D-glucosaminyl L-malate deacetylase Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway%2C the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN- Mal)%3B Belongs to the PIGL family gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00608 BL14DL4_00609 BL14DL4_00609 mgsA mgsA 534272 534685 - Methylglyoxal synthase Belongs to the methylglyoxal synthase family%3B KEGG: amc:MADE_1002670 methylglyoxal synthase gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00609 BL14DL4_0061 BL14DL4_0061 BL14DL4_0061 49725 50726 - SPBc2 prophage-derived recombinase-like protein YomM Belongs to the 'phage' integrase family gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0061 BL14DL4_00610 BL14DL4_00610 dapB dapB 534705 535508 - 4-hydroxy-tetrahydrodipicolinate reductase Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate%3B Belongs to the DapB family%3B KEGG: bli:BL02758 4-hydroxy-tetrahydrodipicolinate reductase gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00610 BL14DL4_00611 BL14DL4_00611 aroA aroA 535521 535859 - 3-phosphoshikimate 1-carboxyvinyltransferase KEGG: eao:BD94_0226 3-phosphoshikimate 1-carboxyvinyltransferase gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00611 BL14DL4_00612 BL14DL4_00612 BL14DL4_00612 535997 536869 + UPF0750 membrane protein YpjC Belongs to the UPF0750 family gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00612 BL14DL4_00613 BL14DL4_00613 BL14DL4_00613 536912 537712 - uncharacterized protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00613 BL14DL4_00614 BL14DL4_00614 BL14DL4_00614 537787 538371 - uncharacterized protein gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00614 BL14DL4_00615 BL14DL4_00615 BL14DL4_00615 538609 539376 - Menaquinol-cytochrome c reductase cytochrome b/c subunit Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family%3B Contains 1 cytochrome c domain gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00615 BL14DL4_00616 BL14DL4_00616 BL14DL4_00616 539409 540083 - Menaquinol-cytochrome c reductase cytochrome b subunit Component of the menaquinol-cytochrome c reductase complex. Belongs to the cytochrome b family gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00616 BL14DL4_00617 BL14DL4_00617 qcrA qcrA 540086 540592 - Menaquinol-cytochrome c reductase iron-sulfur subunit Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein. Contains 1 Rieske domain%3B KEGG: bli:BL02762 menaquinol-cytochrome c reductase iron-sulfur subunit%3B With a cytochrome as acceptor gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00617 BL14DL4_00618 BL14DL4_00618 BL14DL4_00618 540739 541185 - uncharacterized protein gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00618 BL14DL4_00619 BL14DL4_00619 BL14DL4_00619 541267 541806 - UPF0302 protein Belongs to the UPF0302 family gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00619 BL14DL4_0062 BL14DL4_0062 BL14DL4_0062 50740 51159 - SPBc2 prophage-derived uncharacterized protein YomN gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0062 BL14DL4_00620 BL14DL4_00620 BL14DL4_00620 541875 543149 - TPR repeat-containing protein YpiA Contains 9 TPR repeats gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00620 BL14DL4_00621 BL14DL4_00621 BL14DL4_00621 543383 544669 - 3-phosphoshikimate 1-carboxyvinyltransferase Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate%3B Belongs to the EPSP synthase family%3B KEGG: bli:BL02766 3-phosphoshikimate 1-carboxyvinyltransferase gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00621 BL14DL4_00622 BL14DL4_00622 BL14DL4_00622 544680 545795 - Prephenate dehydrogenase Contains 1 ACT domain%3B Contains 1 prephenate/arogenate dehydrogenase domain%3B KEGG: bli:BL02768 prephenate dehydrogenase gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00622 BL14DL4_00623 BL14DL4_00623 hisC hisC 545849 546934 - Histidinol-phosphate transaminase Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily%3B KEGG: bld:BLi02397 histidinol-phosphate aminotransferase gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00623 BL14DL4_00624 BL14DL4_00624 trpA trpA 546944 547747 - Tryptophan synthase The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate%3B Belongs to the TrpA family%3B KEGG: bli:BL02770 tryptophan synthase alpha chain gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00624 BL14DL4_00625 BL14DL4_00625 trpB trpB 547716 548942 - Tryptophan synthase The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine%3B Belongs to the TrpB family%3B KEGG: bli:BL02771 tryptophan synthase beta chain gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00625 BL14DL4_00626 BL14DL4_00626 trpF trpF 548923 549579 - Phosphoribosylanthranilate isomerase Belongs to the TrpF family%3B KEGG: bsr:I33_2325 phosphoribosylanthranilate isomerase gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00626 BL14DL4_00627 BL14DL4_00627 trpC trpC 549579 550337 - Indole-3-glycerol-phosphate synthase Belongs to the TrpC family%3B KEGG: bli:BL02773 indole-3-glycerol phosphate synthase gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00627 BL14DL4_00628 BL14DL4_00628 trpD trpD 550330 551346 - Anthranilate phosphoribosyltransferase Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: bli:BL02774 anthranilate phosphoribosyltransferase gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00628 BL14DL4_00629 BL14DL4_00629 trpE trpE 551318 552865 - Anthranilate synthase Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate%2C an intermediate in the biosynthesis of L-tryptophan. In the first step%2C the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG%2C TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)%3B Belongs to the anthranilate synthase component I family%3B KEGG: bli:BL02775 anthranilate synthase component I gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00629 BL14DL4_0063 BL14DL4_0063 BL14DL4_0063 51161 51646 - SPBc2 prophage-derived uncharacterized protein YomO gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0063 BL14DL4_00630 BL14DL4_00630 aroH aroH 553111 553494 - Chorismate mutase Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis%3B Contains 1 chorismate mutase aroH-type domain%3B KEGG: bsu:BSU22690 chorismate mutase gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00630 BL14DL4_00631 BL14DL4_00631 aroB aroB 553491 554579 - 3-dehydroquinate synthase Belongs to the dehydroquinate synthase family%3B KEGG: bli:BL02777 3-dehydroquinate synthase gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00631 BL14DL4_00632 BL14DL4_00632 aroC aroC 554579 555751 - Chorismate synthase Catalyzes the anti-1%2C4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate%2C which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system%3B Belongs to the chorismate synthase family%3B KEGG: gsu:GSU2027 chorismate synthase gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00632 BL14DL4_00633 BL14DL4_00633 cheR cheR 555823 556590 - Protein-glutamate O-methyltransferase Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents. Contains 1 cheR-type methyltransferase domain%3B KEGG: bli:BL02780 chemotaxis protein methyltransferase CheR gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00633 BL14DL4_00634 BL14DL4_00634 BL14DL4_00634 556730 557176 - Nucleoside-diphosphate kinase Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism%2C using a phosphorylated active-site intermediate%3B Belongs to the NDK family%3B KEGG: eco:b2518 nucleoside-diphosphate kinase gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00634 BL14DL4_00635 BL14DL4_00635 BL14DL4_00635 557301 558263 - Heptaprenyl diphosphate synthase Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bli:BL02782 heptaprenyl diphosphate synthase gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00635 BL14DL4_00636 BL14DL4_00636 ubiE ubiE 558293 558991 - Demethylmenaquinone methyltransferase Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: bsu:BSU22750 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00636 BL14DL4_00637 BL14DL4_00637 BL14DL4_00637 558994 559779 - Heptaprenyl diphosphate synthase Supplies heptaprenyl diphosphate%2C the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7)%3B KEGG: blh:BaLi_c25000 heptaprenyl diphosphate synthase gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00637 BL14DL4_00638 BL14DL4_00638 BL14DL4_00638 559913 560149 - Transcription attenuation protein MtrB Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan%3B Belongs to the MtrB family gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00638 BL14DL4_00639 BL14DL4_00639 gch1 gch1 560171 560740 - GTP cyclohydrolase I Belongs to the GTP cyclohydrolase I family%3B KEGG: bsu:BSU22780 GTP cyclohydrolase I gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00639 BL14DL4_0064 BL14DL4_0064 BL14DL4_0064 51685 51876 - hypothetical protein gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0064 BL14DL4_00640 BL14DL4_00640 BL14DL4_00640 560947 561225 - DNA-binding protein HU-1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00640 BL14DL4_00641 BL14DL4_00641 BL14DL4_00641 561643 563121 - Stage IV sporulation protein ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Directs the assembly of the coat and exosporium to an area around the forespore gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00641 BL14DL4_00642 BL14DL4_00642 BL14DL4_00642 563323 564039 - uncharacterized protein gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00642 BL14DL4_00643 BL14DL4_00643 BL14DL4_00643 564062 564265 - uncharacterized protein gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00643 BL14DL4_00644 BL14DL4_00644 gpsA gpsA 564593 565633 - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: mmn:midi_00920 glycerol-3-phosphate dehydrogenase (NAD(P)+) gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00644 BL14DL4_00645 BL14DL4_00645 BL14DL4_00645 565649 566959 - GTPase Der GTPase that plays an essential role in the late steps of ribosome biogenesis%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngA (Der) GTPase family%3B Contains 2 EngA-type G (guanine nucleotide-binding) domains%3B Contains 1 KH-like domain gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00645 BL14DL4_00646 BL14DL4_00646 BL14DL4_00646 567122 567316 - uncharacterized protein gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00646 BL14DL4_00647 BL14DL4_00647 BL14DL4_00647 567313 568212 - uncharacterized protein gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00647 BL14DL4_00648 BL14DL4_00648 BL14DL4_00648 568209 568811 - uncharacterized protein gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00648 BL14DL4_00649 BL14DL4_00649 BL14DL4_00649 568884 569015 + uncharacterized protein gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00649 BL14DL4_0065 BL14DL4_0065 BL14DL4_0065 51873 52199 - hypothetical protein gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0065 BL14DL4_00650 BL14DL4_00650 BL14DL4_00650 569045 570100 - Isopentenyl-diphosphate Delta-isomerase Involved in the biosynthesis of isoprenoids. Catalyzes the 1%2C3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer%2C dimethylallyl diphosphate (DMAPP)%3B Belongs to the IPP isomerase type 2 family%3B KEGG: bli:BL02217 isopentenyl-diphosphate delta-isomerase gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00650 BL14DL4_00651 BL14DL4_00651 BL14DL4_00651 570110 571258 - 30S ribosomal protein S1 like protein Plays a role in sporulation%3B Belongs to the ribosomal protein S1P family%3B Contains 4 S1 motif domains gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00651 BL14DL4_00652 BL14DL4_00652 BL14DL4_00652 571476 572156 - UMP/CMP kinase Belongs to the cytidylate kinase family. Type 1 subfamily%3B KEGG: gxy:GLX_11090 cytidylate kinase gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00652 BL14DL4_00653 BL14DL4_00653 BL14DL4_00653 572236 572412 - uncharacterized protein gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00653 BL14DL4_00654 BL14DL4_00654 BL14DL4_00654 572574 573926 - Sporulation protein YpeB Required for spore cortex hydrolysis during germination. Appears to be required for either expression%2C localization%2C activation or function of SleB. Belongs to the YpeB family gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00654 BL14DL4_00655 BL14DL4_00655 cwlJ cwlJ 573943 574908 - N-acetylmuramoyl-L-alanine amidase Required for spore cortex hydrolysis during germination%3B Belongs to the SleB family%3B KEGG: bli:BL02222 N-acetylmuramoyl-L-alanine amidase gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00655 BL14DL4_00656 BL14DL4_00656 BL14DL4_00656 575047 575715 - Protease PrsW Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results%2C after two other proteolytic steps catalyzed by the RasP and ClpXP proteases%2C in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity)%3B Belongs to the protease PrsW family gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00656 BL14DL4_00657 BL14DL4_00657 ansA ansA 575795 576763 - Asparaginase Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bli:BL02224 L-asparaginase gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00657 BL14DL4_00658 BL14DL4_00658 trxB trxB 576873 577868 - Thioredoxin-disulfide reductase KEGG: bld:BLi02434 thioredoxin reductase (NADPH) gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00658 BL14DL4_00659 BL14DL4_00659 gudB gudB 577928 579202 - Glutamate dehydrogenase GudB seems to be intrinsically inactive%2C however spontaneous mutations removing a 9-bp direct repeat within the wild-type gudB sequence activated the GudB protein and allowed more-efficient utilization of amino acids of the glutamate family. This insertion presumably causes severe destabilization of the fold of the protein%2C leading to an inactive enzyme that is very quickly degraded. The cryptic GudB serves as a buffer that may compensate for mutations in the rocG gene and that can also be decryptified for the utilization of glutamate as a single carbon source in the absence of arginine. It is unable to synthesize glutamate%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bli:BL02226 glutamate dehydrogenase gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00659 BL14DL4_0066 BL14DL4_0066 BL14DL4_0066 52212 53840 - SPBc2 prophage-derived uncharacterized protein YomR gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0066 BL14DL4_00660 BL14DL4_00660 BL14DL4_00660 579398 579982 - Adapter protein MecA Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00660 BL14DL4_00661 BL14DL4_00661 BL14DL4_00661 580136 580921 - uncharacterized protein gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00661 BL14DL4_00662 BL14DL4_00662 BL14DL4_00662 581000 581452 - uncharacterized protein gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00662 BL14DL4_00663 BL14DL4_00663 BL14DL4_00663 581511 582290 - uncharacterized protein gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00663 BL14DL4_00664 BL14DL4_00664 BL14DL4_00664 582232 582876 - uncharacterized protein gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00664 BL14DL4_00665 BL14DL4_00665 BL14DL4_00665 582870 584366 - DNA helicase DNA helicase%3B Belongs to the helicase family. RecQ subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02232 ATP-dependent DNA helicase RecQ gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00665 BL14DL4_00666 BL14DL4_00666 BL14DL4_00666 584359 585453 - DNA helicase KEGG: drm:Dred_1261 ATP-dependent DNA helicase RecQ gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00666 BL14DL4_00667 BL14DL4_00667 BL14DL4_00667 585681 585929 + Ferredoxin Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin may act as a phosphodonor to cytochrome P450 BioI%3B Contains 1 4Fe-4S ferredoxin-type domain gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00667 BL14DL4_00668 BL14DL4_00668 BL14DL4_00668 586083 586661 - Riboflavin transporter FmnP Mediates uptake of riboflavin and roseoflavin%2C a toxic riboflavin analo%3B may also transport FMN. Probably a riboflavin- binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the prokaryotic riboflavin transporter (P- RFT) (TC 2. A. 87) family gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00668 BL14DL4_00669 BL14DL4_00669 serA serA 587204 588781 + Phosphoglycerate dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU23070 D-3-phosphoglycerate dehydrogenase gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00669 BL14DL4_0067 BL14DL4_0067 BL14DL4_0067 53843 54208 - SPBc2 prophage-derived uncharacterized protein YomS gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0067 BL14DL4_00670 BL14DL4_00670 lytM lytM 588830 589654 - Lysostaphin Belongs to the peptidase M23B family%3B KEGG: har:HEAR2799 lysostaphin gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00670 BL14DL4_00671 BL14DL4_00671 BL14DL4_00671 589779 590705 - Sigma-X negative effector gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00671 BL14DL4_00672 BL14DL4_00672 BL14DL4_00672 590821 591405 - RNA polymerase sigma factor SigX Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism. Belongs to the sigma-70 factor family. ECF subfamily gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00672 BL14DL4_00673 BL14DL4_00673 BL14DL4_00673 591680 592594 - Transcriptional regulator LytR Attenuator role for operon expression%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00673 BL14DL4_00674 BL14DL4_00674 BL14DL4_00674 593135 593174 + Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00674 BL14DL4_00675 BL14DL4_00675 BL14DL4_00675 593790 594923 - hypothetical protein gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00675 BL14DL4_00676 BL14DL4_00676 BL14DL4_00676 594920 596371 - Sensor protein VanSB Member of the two-component regulatory system VanS/VanR. Activates the transcription of vanH%2C vanA and vanX in response to vancomycin which results in vancomycin resistance. VanS activates VanR by phosphorylation. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gme:Gmet_2737 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00676 BL14DL4_00677 BL14DL4_00677 BL14DL4_00677 596375 597076 - Transcriptional regulatory protein ResD Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00677 BL14DL4_00678 BL14DL4_00678 resE resE 597529 599310 - Histidine kinase Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU23110 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00678 BL14DL4_00679 BL14DL4_00679 BL14DL4_00679 599307 600029 - Transcriptional regulatory protein ResD Member of the two-component regulatory system ResD/ResE. Required for the expression of resA%2C ctaA%2C qcrABC and fn%3B activation role in global regulation of aerobic and anaerobic respiration%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00679 BL14DL4_0068 BL14DL4_0068 BL14DL4_0068 54317 54709 - Ryncolin-4 Initiates complement activation and/or interferes in platelet aggregation and/or blood coagulation%3B Belongs to the ficolin lectin family. Veficolin subfamily%3B Contains 1 collagen-like domain%3B Contains 1 fibrinogen C-terminal domain gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0068 BL14DL4_00680 BL14DL4_00680 BL14DL4_00680 600174 601349 - Cytochrome c bioproteinis protein ResC Required for the biogenesis of c-type cytochromes%3B Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00680 BL14DL4_00681 BL14DL4_00681 BL14DL4_00681 601375 603006 - Cytochrome c bioproteinis protein ResB Required for the biogenesis of c-type cytochromes gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00681 BL14DL4_00682 BL14DL4_00682 BL14DL4_00682 603003 603536 - Thiol-disulfide oxidoreductase ResA Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA%2C leading to breakage of disulfide bonds in apocytochrome%3B following this reduction heme can be covalently attached%3B Belongs to the thioredoxin family. ResA subfamily%3B Contains 1 thioredoxin domain gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00682 BL14DL4_00683 BL14DL4_00683 rluB rluB 603624 604358 - 23S rRNA pseudouridine(2605) synthase Responsible for synthesis of pseudouridine from uracil- 2633 in 23S ribosomal RNA. Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: sdl:Sdel_0065 23S rRNA pseudouridine2605 synthase gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00683 BL14DL4_00684 BL14DL4_00684 BL14DL4_00684 604517 605053 - Spore maturation protein Involved in spore core dehydratio%3B might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure. Belongs to the SpmB family gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00684 BL14DL4_00685 BL14DL4_00685 BL14DL4_00685 605058 605645 - Spore maturation protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00685 BL14DL4_00686 BL14DL4_00686 BL14DL4_00686 605633 606787 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bli:BL01881 D-alanyl-D-alanine carboxypeptidase gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00686 BL14DL4_00687 BL14DL4_00687 BL14DL4_00687 606940 607431 - uncharacterized protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00687 BL14DL4_00688 BL14DL4_00688 BL14DL4_00688 607546 608139 - Segregation and condensation protein Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpB family gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00688 BL14DL4_00689 BL14DL4_00689 BL14DL4_00689 608129 608884 - Segregation and condensation protein Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves%3B Belongs to the ScpA family gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00689 BL14DL4_0069 BL14DL4_0069 BL14DL4_0069 54749 55582 - SPBc2 prophage-derived uncharacterized protein YomU gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0069 BL14DL4_00690 BL14DL4_00690 BL14DL4_00690 609067 609162 + hypothetical protein gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00690 BL14DL4_00691 BL14DL4_00691 BL14DL4_00691 609283 609804 + uncharacterized protein gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00691 BL14DL4_00692 BL14DL4_00692 BL14DL4_00692 609815 610189 - Protein RibT Involved in riboflavin biosynthesis. Contains 1 N-acetyltransferase domain gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00692 BL14DL4_00693 BL14DL4_00693 ribH ribH 610291 610755 - 6%2C7-dimethyl-8-ribityllumazine synthase Catalyzes the formation of 6%2C7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3%2C4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin%3B Belongs to the DMRL synthase family%3B KEGG: bli:BL01888 6%2C7-dimethyl-8-ribityllumazine synthase gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00693 BL14DL4_00694 BL14DL4_00694 BL14DL4_00694 610790 611986 - 3%2C4-dihydroxy-2-butanone-4-phosphate synthase Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3%2C4-dihydroxy-2-butanone 4-phosphate%3B Catalyzes the conversion of GTP to 2%2C5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP)%2C formate and pyrophosphate%3B In the N-terminal sectio%3B belongs to the DHBP synthase family%3B In the C-terminal sectio%3B belongs to the GTP cyclohydrolase II family%3B KEGG: bid:Bind_0944 3%2C4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00694 BL14DL4_00695 BL14DL4_00695 ribE ribE 612008 612655 - Riboflavin synthase Catalyzes the dismutation of two molecules of 6%2C7- dimethyl-8-ribityllumazine%2C resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil%3B Contains 2 lumazine-binding repeats%3B KEGG: hdu:HD1162 riboflavin synthase gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00695 BL14DL4_00696 BL14DL4_00696 ribD ribD 612667 613755 - Diaminohydroxyphosphoribosylaminopyrimidine deaminase Converts 2%2C5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2%2C4(1h%2C3h)- pyrimidinedione 5'-phosphate. In the N-terminal sectio%3B belongs to the cytidine and deoxycytidylate deaminase family%3B In the C-terminal sectio%3B belongs to the HTP reductase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL01891 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00696 BL14DL4_00697 BL14DL4_00697 BL14DL4_00697 614116 614460 - uncharacterized protein gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00697 BL14DL4_00698 BL14DL4_00698 BL14DL4_00698 614723 616909 - 2'%2C3'-cyclic-nucleotide 3'-phosphodiesterase KEGG: fnu:FN1603 2'%2C3'-cyclic-nucleotide 3'-phosphodiesterase gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00698 BL14DL4_00699 BL14DL4_00699 BL14DL4_00699 617036 617473 - Small heat shock protein C2 Belongs to the small heat shock protein (HSP20) family gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00699 BL14DL4_0070 BL14DL4_0070 BL14DL4_0070 55614 56324 - SPBc2 prophage-derived uncharacterized protein YomV gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0070 BL14DL4_00700 BL14DL4_00700 BL14DL4_00700 617632 617937 - hypothetical protein gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00700 BL14DL4_00701 BL14DL4_00701 rapA rapA 617927 619057 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bli:BL05244 response regulator aspartate phosphatase A (stage 0 sporulation protein L)%3B Acting on ester bonds gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00701 BL14DL4_00702 BL14DL4_00702 ppiB ppiB 619288 619725 - Peptidylprolyl isomerase PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family%3B Contains 1 PPIase cyclophilin-type domain%3B KEGG: bli:BL05245 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00702 BL14DL4_00703 BL14DL4_00703 BL14DL4_00703 620062 620958 + uncharacterized protein gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00703 BL14DL4_00704 BL14DL4_00704 BL14DL4_00704 620955 621815 - UPF0714 protein YndL Belongs to the UPF0714 family gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00704 BL14DL4_00705 BL14DL4_00705 lysA lysA 622054 623373 - Diaminopimelate decarboxylase Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine%3B Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily%3B KEGG: bsu:BSU23380 diaminopimelate decarboxylase gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00705 BL14DL4_00706 BL14DL4_00706 BL14DL4_00706 623737 624066 + hypothetical protein gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00706 BL14DL4_00707 BL14DL4_00707 BL14DL4_00707 624111 625583 - Stage V sporulation protein AF Belongs to the GerABKA family gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00707 BL14DL4_00708 BL14DL4_00708 BL14DL4_00708 625543 626145 - Stage V sporulation protein AE gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00708 BL14DL4_00709 BL14DL4_00709 BL14DL4_00709 626152 626502 - Stage V sporulation protein AEB gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00709 BL14DL4_0071 BL14DL4_0071 BL14DL4_0071 56321 56851 - SPBc2 prophage-derived uncharacterized protein YomW gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0071 BL14DL4_00710 BL14DL4_00710 BL14DL4_00710 626504 627523 - Stage V sporulation protein AD gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00710 BL14DL4_00711 BL14DL4_00711 BL14DL4_00711 627536 627985 - Stage V sporulation protein AC gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00711 BL14DL4_00712 BL14DL4_00712 BL14DL4_00712 627999 628424 - Stage V sporulation protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00712 BL14DL4_00713 BL14DL4_00713 BL14DL4_00713 628414 629034 - Stage V sporulation protein AA gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00713 BL14DL4_00714 BL14DL4_00714 BL14DL4_00714 629202 629969 - RNA polymerase sigma-F factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00714 BL14DL4_00715 BL14DL4_00715 BL14DL4_00715 629982 630422 - Non-specific serine/threonine protein kinase Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition%3B Belongs to the anti-sigma-factor family%3B KEGG: bsu:BSU23460 stage II sporulation protein AB (anti-sigma F factor) gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00715 BL14DL4_00716 BL14DL4_00716 BL14DL4_00716 630419 630772 - Anti-sigma F factor antagonist In the phosphorylated form it could act as an anti-anti- sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00716 BL14DL4_00717 BL14DL4_00717 dacC dacC 630866 632038 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bli:BL00775 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00717 BL14DL4_00718 BL14DL4_00718 punA punA 632196 633011 - Purine-nucleoside phosphorylase The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules%2C with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine%2C inosine%2C 2'-deoxyguanosine and 2'-deoxyinosine%3B Belongs to the PNP/MTAP phosphorylase family%3B KEGG: bli:BL00774 purine-nucleoside phosphorylase gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00718 BL14DL4_00719 BL14DL4_00719 deoB deoB 633023 634207 - Phosphopentomutase Phosphotransfer between the C1 and C5 carbon atoms of pentose%3B Belongs to the phosphopentomutase family%3B KEGG: bli:BL00772 phosphopentomutase gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00719 BL14DL4_0072 BL14DL4_0072 BL14DL4_0072 56848 57507 - SPBc2 prophage-derived uncharacterized protein YomX gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0072 BL14DL4_00720 BL14DL4_00720 BL14DL4_00720 634401 635291 - Tyrosine recombinase XerD Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerD subfamily gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00720 BL14DL4_00721 BL14DL4_00721 BL14DL4_00721 635298 635522 - putative membrane protein YqzK gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00721 BL14DL4_00722 BL14DL4_00722 BL14DL4_00722 635643 636092 - Ferric uptake regulation protein Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes. Belongs to the Fur family gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00722 BL14DL4_00723 BL14DL4_00723 BL14DL4_00723 636211 636867 - Stage II sporulation protein Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00723 BL14DL4_00724 BL14DL4_00724 BL14DL4_00724 636981 638327 - Cellobiose permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00724 BL14DL4_00725 BL14DL4_00725 celA celA 638347 638646 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: eoj:ECO26_2139 PTS system%2C cellobiose-specific IIB component gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00725 BL14DL4_00726 BL14DL4_00726 BL14DL4_00726 638911 639834 + Nicotinamide riboside transporter High-affinity pH-dependent nicotinamide riboside transporter which also transports thiamine with low affinity. Involved in 5-fluorocytosine sensitivity%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00726 BL14DL4_00727 BL14DL4_00727 BL14DL4_00727 639795 640385 + putative allantoin permease Transport of allantoin%3B Belongs to the purine-cytosine permease (2. A. 39) family gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00727 BL14DL4_00728 BL14DL4_00728 BL14DL4_00728 640506 641162 + Ribosomal-protein-serine acetyltransferase This enzyme acetylates the N-terminal serine of ribosomal protein L7/L12. Belongs to the acetyltransferase family. RimL subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bce:BC2017 null%3B Transferring groups other than amino-acyl groups gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00728 BL14DL4_00729 BL14DL4_00729 BL14DL4_00729 640999 641370 - uncharacterized protein gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00729 BL14DL4_0073 BL14DL4_0073 BL14DL4_0073 57494 57724 - SPBc2 prophage-derived uncharacterized protein YomY gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0073 BL14DL4_00730 BL14DL4_00730 BL14DL4_00730 641435 641887 - Protein ElaA Belongs to the UPF0039 (ElaA) family%3B Contains 1 N-acetyltransferase domain gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00730 BL14DL4_00731 BL14DL4_00731 BL14DL4_00731 641909 643072 - uncharacterized protein To M. jannaschii MJ0043 N-terminal region gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00731 BL14DL4_00732 BL14DL4_00732 nudF nudF 643069 643635 - ADP-ribose diphosphatase Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity)%3B Belongs to the Nudix hydrolase family. NudF subfamily%3B Contains 1 nudix hydrolase domain%3B KEGG: bli:BL05253 ADP-ribose pyrophosphatase gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00732 BL14DL4_00733 BL14DL4_00733 BL14DL4_00733 643703 643879 + hypothetical protein gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00733 BL14DL4_00734 BL14DL4_00734 BL14DL4_00734 643931 644536 + putative HTH-type transcriptional regulator YdgC Contains 1 HTH tetR-type DNA-binding domain gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00734 BL14DL4_00735 BL14DL4_00735 BL14DL4_00735 644542 644889 + uncharacterized protein gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00735 BL14DL4_00736 BL14DL4_00736 BL14DL4_00736 644963 645883 + putative oxidoreductase YqkF Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00736 BL14DL4_00737 BL14DL4_00737 BL14DL4_00737 645926 646159 - uncharacterized protein gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00737 BL14DL4_00738 BL14DL4_00738 BL14DL4_00738 646316 647245 + uncharacterized protein gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00738 BL14DL4_00739 BL14DL4_00739 BL14DL4_00739 647269 647508 - uncharacterized protein gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00739 BL14DL4_0074 BL14DL4_0074 BL14DL4_0074 57721 58119 - SPBc2 prophage-derived uncharacterized protein YomZ gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0074 BL14DL4_00740 BL14DL4_00740 BL14DL4_00740 647522 647845 - uncharacterized protein gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00740 BL14DL4_00741 BL14DL4_00741 BL14DL4_00741 647954 648091 + hypothetical protein gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00741 BL14DL4_00742 BL14DL4_00742 BL14DL4_00742 648860 648945 + Dephospho-CoA kinase%3B nonfunctional due to frameshift pseudo gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00742 BL14DL4_00743 BL14DL4_00743 BL14DL4_00743 649133 649501 - Glutathione transferase Contains 1 ABM domain%3B KEGG: thi:THI_2919 glutathione S-transferase gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00743 BL14DL4_00744 BL14DL4_00744 BL14DL4_00744 650069 650683 + Triacylglycerol lipase Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups%3B Belongs to the AB hydrolase superfamily%3B KEGG: bli:BL05255 triacylglycerol lipase gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00744 BL14DL4_00745 BL14DL4_00745 BL14DL4_00745 650829 651041 - hypothetical protein gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00745 BL14DL4_00746 BL14DL4_00746 BL14DL4_00746 651311 652840 + Periplasmic dipeptide transport protein Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis. Belongs to the bacterial solute-binding protein 5 family gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00746 BL14DL4_00747 BL14DL4_00747 BL14DL4_00747 652837 653778 + Putative oligopeptide transport system permease protein oppB2 Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for the translocation of the substrate across the membrane. Important for S. aureus growth and survival during the infection process (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00747 BL14DL4_00748 BL14DL4_00748 BL14DL4_00748 653775 654596 + Dipeptide transport system permease protein DppC Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00748 BL14DL4_00749 BL14DL4_00749 BL14DL4_00749 654598 655440 + Oligopeptide transport ATP-binding protein OppD Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00749 BL14DL4_0075 BL14DL4_0075 BL14DL4_0075 58131 58601 - SPBc2 prophage-derived uncharacterized protein YonA gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0075 BL14DL4_00750 BL14DL4_00750 BL14DL4_00750 655440 656225 + putative iron transport system ATP-binding protein Part of an ATP-driven transport system HI_0359/HI_0360/HI_0361/HI_0362 for iron. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00750 BL14DL4_00751 BL14DL4_00751 BL14DL4_00751 656241 657599 + Multidrug export protein MepA Multidrug resistance efflux protein%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family. MepA subfamily gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00751 BL14DL4_00752 BL14DL4_00752 BL14DL4_00752 657622 658263 - hypothetical protein gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00752 BL14DL4_00753 BL14DL4_00753 BL14DL4_00753 658357 658446 - hypothetical protein gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00753 BL14DL4_00754 BL14DL4_00754 BL14DL4_00754 658474 658812 - SPBc2 prophage-derived uncharacterized protein YolD gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00754 BL14DL4_00755 BL14DL4_00755 BL14DL4_00755 658828 660090 - Putative UV-damage repair protein UvrX Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00755 BL14DL4_00756 BL14DL4_00756 BL14DL4_00756 660363 660575 + uncharacterized protein gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00756 BL14DL4_00757 BL14DL4_00757 BL14DL4_00757 660703 661941 + putative MFS-type transporter YqjV Belongs to the major facilitator superfamily. TCR/Tet family gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00757 BL14DL4_00758 BL14DL4_00758 gpmB gpmB 661992 662375 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) KEGG: mlu:Mlut_09490 probable phosphoglycerate mutase gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00758 BL14DL4_00759 BL14DL4_00759 coaA coaA 662390 663349 - Pantothenate kinase Belongs to the prokaryotic pantothenate kinase family%3B KEGG: psy:PCNPT3_12895 type I pantothenate kinase gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00759 BL14DL4_0076 BL14DL4_0076 BL14DL4_0076 58956 59651 - SPBc2 prophage-derived uncharacterized protein YonB gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0076 BL14DL4_00760 BL14DL4_00760 BL14DL4_00760 663610 664575 - hypothetical protein gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00760 BL14DL4_00761 BL14DL4_00761 BL14DL4_00761 664553 665215 - Iron-chelate-transporting ATPase Part of a binding-protein-dependent transport system for arginine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: aap:NT05HA_1149 iron complex transport system ATP-binding protein gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00761 BL14DL4_00762 BL14DL4_00762 BL14DL4_00762 665331 665819 - hypothetical protein gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00762 BL14DL4_00763 BL14DL4_00763 BL14DL4_00763 666241 666501 + hypothetical protein gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00763 BL14DL4_00764 BL14DL4_00764 BL14DL4_00764 666807 667313 - hypothetical protein gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00764 BL14DL4_00765 BL14DL4_00765 BL14DL4_00765 667367 668089 - UPF0714 protein YmaC Belongs to the UPF0714 family gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00765 BL14DL4_00766 BL14DL4_00766 BL14DL4_00766 668521 669303 - Hydroxysteroid 11-beta-dehydrogenase 1-like protein Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00766 BL14DL4_00767 BL14DL4_00767 gloB gloB 669313 670266 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily%3B KEGG: nph:NP_3944A hydroxyacylglutathione hydrolase gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00767 BL14DL4_00768 BL14DL4_00768 BL14DL4_00768 670656 671477 + Pyrroline-5-carboxylate reductase Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline%3B Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bsu:BSU23800 pyrroline-5-carboxylate reductase gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00768 BL14DL4_00769 BL14DL4_00769 BL14DL4_00769 671536 673140 - uncharacterized protein To B. subtilis RocB gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00769 BL14DL4_0077 BL14DL4_0077 BL14DL4_0077 59692 60294 - SPBc2 prophage-derived uncharacterized protein YonC gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0077 BL14DL4_00770 BL14DL4_00770 BL14DL4_00770 673268 674347 + NADPH dehydrogenase Catalyzes the reduction of the double bond of an array of alpha%2Cbeta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes%3B Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily%3B KEGG: bli:BL00797 NADPH2 dehydrogenase gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00770 BL14DL4_00771 BL14DL4_00771 BL14DL4_00771 674464 675225 + uncharacterized protein gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00771 BL14DL4_00772 BL14DL4_00772 BL14DL4_00772 675259 675408 - 50S ribosomal protein L33 Belongs to the ribosomal protein L33P family gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00772 BL14DL4_00773 BL14DL4_00773 BL14DL4_00773 675528 676451 - Ribonuclease Z Zinc phosphodiesterase%2C which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation%2C by removing a 3'-trailer from precursor tRNA%3B Belongs to the RNase Z family%3B KEGG: ebi:EbC_43140 ribonuclease Z gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00773 BL14DL4_00774 BL14DL4_00774 g6pD g6pD 676670 678148 + Glucose-6-phosphate dehydrogenase (NADP(+)) Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone%3B Belongs to the glucose-6-phosphate dehydrogenase family%3B KEGG: bli:BL01964 glucose-6-phosphate 1-dehydrogenase gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00774 BL14DL4_00775 BL14DL4_00775 BL14DL4_00775 678184 680148 - Putative TRAP transporter large permease protein Belongs to the TRAP transporter large permease family gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00775 BL14DL4_00776 BL14DL4_00776 BL14DL4_00776 680141 680659 - hypothetical protein gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00776 BL14DL4_00777 BL14DL4_00777 BL14DL4_00777 680761 681750 - 31 kDa immunogenic protein gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00777 BL14DL4_00778 BL14DL4_00778 BL14DL4_00778 681997 682710 - Arabinose metabolism transcriptional repressor Transcriptional repressor of the arabinose utilization genes%3B Contains 1 HTH gntR-type DNA-binding domain gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00778 BL14DL4_00779 BL14DL4_00779 bglA bglA 682830 684245 - 6-phospho-beta-glucosidase Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL00115 6-phospho-beta-glucosidase gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00779 BL14DL4_0078 BL14DL4_0078 BL14DL4_0078 60318 61757 - SPBc2 prophage-derived uncharacterized protein YonD gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0078 BL14DL4_00780 BL14DL4_00780 BL14DL4_00780 684261 685577 - Oligo-beta-mannoside permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00780 BL14DL4_00781 BL14DL4_00781 celC celC 685617 685949 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIA type-3 domain%3B KEGG: bli:BL05259 PTS system%2C cellobiose-specific IIA component gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00781 BL14DL4_00782 BL14DL4_00782 BL14DL4_00782 685955 686263 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIB type-3 domain%3B KEGG: eca:ECA3645 PTS system%2C cellobiose-specific IIB component gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00782 BL14DL4_00783 BL14DL4_00783 phoA phoA 686413 688074 - Alkaline phosphatase Belongs to the alkaline phosphatase family%3B KEGG: bli:BL01381 alkaline phosphatase gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00783 BL14DL4_00784 BL14DL4_00784 BL14DL4_00784 688214 688999 - Glucose 1-dehydrogenase (NAD(P)(+)) Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL01382 glucose 1-dehydrogenase gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00784 BL14DL4_00785 BL14DL4_00785 gntZ gntZ 689117 690526 - Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NADP to NADPH%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: eco:b2029 6-phosphogluconate dehydrogenase gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00785 BL14DL4_00786 BL14DL4_00786 dpo4 dpo4 690613 691869 - DNA-directed DNA polymerase Poorly processive%2C error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks%2C which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis%2C in conjunction with the beta clamp from PolIII (By similarity)%3B Belongs to the DNA polymerase type-Y family%3B Contains 1 umuC domain%3B KEGG: bli:BL01384 DNA polymerase IV gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00786 BL14DL4_00787 BL14DL4_00787 BL14DL4_00787 691950 692237 + Membrane protein insertion and folding monitor Sensor protein that upregulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA/SpoIIIJ) is limited. Acts as a ribosome-nascent chain complex. When the primary membrane protein insertase activity or level is reduced%2C the membrane insertion of MifM is impaired%2C which induces arrest of MifM translation and unfolding of the mRNA hairpin. Unfolding leads to translation of the downstream gene%2C which encodes the secondary membrane protein insertase MisCB/YqjG. Translation arrest of MifM is mediated by interaction of its C-terminal domain with the ribosomal polypeptide exit tunnel. Undergoes multisite stalling%2C which may allow a sufficient duration of ribosomal stalling and consequently sufficient levels of MisCB/YqjG gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00787 BL14DL4_00788 BL14DL4_00788 BL14DL4_00788 692286 693110 + Membrane protein insertase MisCB Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. It has an overlapping%2C although partly distinct%2C function compared to SpoIIIJ(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00788 BL14DL4_00789 BL14DL4_00789 BL14DL4_00789 693271 694389 - Propionyl-CoA carboxylase Could be a peptidase. Belongs to the peptidase M20A family%3B KEGG: bya:BANAU_2374 propionyl-CoA carboxylase beta chain gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00789 BL14DL4_0079 BL14DL4_0079 BL14DL4_0079 61792 63312 - SPBc2 prophage-derived uncharacterized protein YonE gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0079 BL14DL4_00790 BL14DL4_00790 BL14DL4_00790 694410 695939 - Propionyl-CoA carboxylase Belongs to the AccD/PCCB family%3B Contains 1 carboxyltransferase domain%3B KEGG: bli:BL01386 propionyl-CoA carboxylase beta chain gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00790 BL14DL4_00791 BL14DL4_00791 BL14DL4_00791 696274 697245 - uncharacterized protein gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00791 BL14DL4_00792 BL14DL4_00792 BL14DL4_00792 697306 698034 - Polar-amino-acid-transporting ATPase Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: sty:STY1436 polar amino acid transport system ATP-binding protein gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00792 BL14DL4_00793 BL14DL4_00793 BL14DL4_00793 698021 698683 - Arginine transport system permease protein ArtQ Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00793 BL14DL4_00794 BL14DL4_00794 BL14DL4_00794 698772 699539 - Arginine-binding extracellular protein ArtP Part of a binding-protein-dependent transport system for arginine%3B Belongs to the bacterial solute-binding protein 3 family gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00794 BL14DL4_00795 BL14DL4_00795 BL14DL4_00795 699590 699763 - hypothetical protein gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00795 BL14DL4_00796 BL14DL4_00796 BL14DL4_00796 699763 700200 - UPF0403 protein Belongs to the UPF0403 family gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00796 BL14DL4_00797 BL14DL4_00797 dagK dagK 700382 701284 + Diacylglycerol kinase (ATP) May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ssd:SPSINT_1652 diacylglycerol kinase (ATP) gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00797 BL14DL4_00798 BL14DL4_00798 bkdB bkdB 701305 702585 - Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: bsu:BSU24030 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00798 BL14DL4_00799 BL14DL4_00799 BL14DL4_00799 702609 703592 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) KEGG: sur:STAUR_4870 2-oxoisovalerate dehydrogenase E1 component beta subunit gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00799 BL14DL4_0080 BL14DL4_0080 BL14DL4_0080 63330 65099 - SPBc2 prophage-derived uncharacterized protein YonF gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0080 BL14DL4_00800 BL14DL4_00800 BL14DL4_00800 703605 704597 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the BCKDHA family%3B KEGG: bli:BL01504 2-oxoisovalerate dehydrogenase E1 component alpha subunit gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00800 BL14DL4_00801 BL14DL4_00801 BL14DL4_00801 704620 706041 - Glutathione-disulfide reductase The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1)%2C lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: abo:ABO_1423 glutathione reductase (NADPH) gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00801 BL14DL4_00802 BL14DL4_00802 BL14DL4_00802 706031 707137 - Butyrate kinase Belongs to the acetokinase family%3B KEGG: bli:BL01502 butyrate kinase gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00802 BL14DL4_00803 BL14DL4_00803 BL14DL4_00803 707176 708270 - Leucine dehydrogenase Catalyzes the reversible deamination of L-leucine to 4- methyl-2-oxopentanoate. Can also use other substrates such as L- isoleucine%2C L-valine and L-2-aminobutyrate. The 2-oxo analogs of branched-chain and straight-chain amino acids serve as good substrates for the reverse reaction%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bsu:BSU24080 leucine dehydrogenase gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00803 BL14DL4_00804 BL14DL4_00804 BL14DL4_00804 708274 709185 - Phosphate butyryltransferase Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate. Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bli:BL01500 phosphate butyryltransferase gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00804 BL14DL4_00805 BL14DL4_00805 dctS dctS 709312 711381 - Histidine kinase Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 2 PAS (PER-ARNT-SIM) domains%3B Contains 1 sigma-54 factor interaction domain%3B KEGG: amt:Amet_2967 two-component system%2C CitB family%2C sensor histidine kinase DctS gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00805 BL14DL4_00806 BL14DL4_00806 BL14DL4_00806 711532 711786 + uncharacterized protein gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00806 BL14DL4_00807 BL14DL4_00807 glpQ glpQ 711837 712562 - Glycerophosphodiester phosphodiesterase Contains 1 GP-PDE domain%3B KEGG: pgb:H744_1c0275 glycerophosphoryl diester phosphodiesterase gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00807 BL14DL4_00808 BL14DL4_00808 BL14DL4_00808 712696 713316 - N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL01514 N-acetylmuramoyl-L-alanine amidase gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00808 BL14DL4_00809 BL14DL4_00809 BL14DL4_00809 713352 713672 - Membrane-bound protein LytA gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00809 BL14DL4_0081 BL14DL4_0081 BL14DL4_0081 65083 66015 - SPBc2 prophage-derived uncharacterized protein YonG gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0081 BL14DL4_00810 BL14DL4_00810 BL14DL4_00810 713946 715376 - hypothetical protein gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00810 BL14DL4_00811 BL14DL4_00811 cysE cysE 715707 716090 - Serine O-acetyltransferase Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: blh:BaLi_c26760 serine O-acetyltransferase gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00811 BL14DL4_00812 BL14DL4_00812 BL14DL4_00812 716220 716516 - hypothetical protein gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00812 BL14DL4_00813 BL14DL4_00813 BL14DL4_00813 716889 717689 - Stage 0 sporulation protein May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB%2C activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity)%3B Contains 1 response regulatory domain gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00813 BL14DL4_00814 BL14DL4_00814 BL14DL4_00814 717979 719319 - SpoIVB peptidase Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter%3B Contains 1 PDZ (DHR) domain%3B Contains 1 peptidase S55 domain%3B KEGG: bli:BL01519 stage IV sporulation protein B gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00814 BL14DL4_00815 BL14DL4_00815 BL14DL4_00815 719445 721175 - DNA repair protein RecN Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers%2C foci that are the site of double-strand DNA break(s)%2C followed by RecO and then RecF. Belongs to the RecN family gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00815 BL14DL4_00816 BL14DL4_00816 BL14DL4_00816 721207 721656 - Arginine repressor Regulates arginine biosynthesis genes%3B Belongs to the ArgR family gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00816 BL14DL4_00817 BL14DL4_00817 tlyA tlyA 721822 722667 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase Belongs to the TlyA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL01522 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00817 BL14DL4_00818 BL14DL4_00818 BL14DL4_00818 722664 724532 - 1-deoxy-D-xylulose-5-phosphate synthase Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: serf:L085_13545 1-deoxy-D-xylulose-5-phosphate synthase gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00818 BL14DL4_00819 BL14DL4_00819 ggpS ggpS 724799 725689 - Dimethylallyltranstransferase Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes%3B Belongs to the FPP/GGPP synthase family%3B KEGG: bli:BL01524 geranylgeranyl diphosphate synthase%2C type II gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00819 BL14DL4_0082 BL14DL4_0082 BL14DL4_0082 66296 66925 + hypothetical protein gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0082 BL14DL4_00820 BL14DL4_00820 xseB xseB 725679 725939 - Exodeoxyribonuclease VII Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseB family%3B KEGG: bli:BL01525 exodeoxyribonuclease VII small subunit gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00820 BL14DL4_00821 BL14DL4_00821 xseA xseA 725932 727281 - Exodeoxyribonuclease VII Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides%2C which are then degraded further into small acid-soluble oligonucleotides%3B Belongs to the XseA family%3B KEGG: bli:BL01526 exodeoxyribonuclease VII large subunit gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00821 BL14DL4_00822 BL14DL4_00822 folD folD 727358 728212 - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Catalyzes the oxidation of 5%2C10- methylenetetrahydrofolate to 5%2C10-methenyltetrahydrofolate and then the hydrolysis of 5%2C10-methenyltetrahydrofolate to 10- formyltetrahydrofolate%3B Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family%3B KEGG: bma:BMA1724 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00822 BL14DL4_00823 BL14DL4_00823 BL14DL4_00823 728229 728618 - N utilization substance protein B like protein Involved in the transcription termination process%3B Belongs to the NusB family gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00823 BL14DL4_00824 BL14DL4_00824 BL14DL4_00824 728911 729321 - uncharacterized protein Belongs to the asp23 family gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00824 BL14DL4_00825 BL14DL4_00825 BL14DL4_00825 729342 730694 - Acetyl-CoA carboxylase Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B KEGG: wgl:WIGMOR_0138 acetyl-CoA carboxylase%2C biotin carboxylase subunit gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00825 BL14DL4_00826 BL14DL4_00826 BL14DL4_00826 730706 731185 - Biotin carboxyl carrier protein of acetyl-CoA carboxylase This protein is a component of the acetyl coenzyme A carboxylase comple%3B first%2C biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. Contains 1 biotinyl-binding domain gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00826 BL14DL4_00827 BL14DL4_00827 BL14DL4_00827 731359 731997 - Stage III sporulation protein AH Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00827 BL14DL4_00828 BL14DL4_00828 BL14DL4_00828 731998 732693 - Stage III sporulation protein AG gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00828 BL14DL4_00829 BL14DL4_00829 BL14DL4_00829 732686 733315 - Stage III sporulation protein AF gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00829 BL14DL4_0083 BL14DL4_0083 BL14DL4_0083 67285 68478 - SPBc2 prophage-derived uncharacterized protein YonJ gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0083 BL14DL4_00830 BL14DL4_00830 BL14DL4_00830 733327 734532 - Stage III sporulation protein AE Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore. Overexpression in the absence of SpoIIIJ is synthetically lethal gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00830 BL14DL4_00831 BL14DL4_00831 BL14DL4_00831 734554 734919 - Stage III sporulation protein AD gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00831 BL14DL4_00832 BL14DL4_00832 BL14DL4_00832 734962 735168 - Stage III sporulation protein AC gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00832 BL14DL4_00833 BL14DL4_00833 BL14DL4_00833 735191 735706 - Stage III sporulation protein gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00833 BL14DL4_00834 BL14DL4_00834 BL14DL4_00834 735700 736623 - Stage III sporulation protein AA gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00834 BL14DL4_00835 BL14DL4_00835 BL14DL4_00835 736715 736996 - uncharacterized protein gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00835 BL14DL4_00836 BL14DL4_00836 BL14DL4_00836 737159 737716 - Elongation factor P Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA%2C thus increasing their reactivity as acceptors for peptidyl transferase%3B Belongs to the elongation factor P family gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00836 BL14DL4_00837 BL14DL4_00837 pepP pepP 737748 738809 - Xaa-Pro aminopeptidase Belongs to the peptidase M24B family%3B KEGG: bsu:BSU24460 Xaa-Pro aminopeptidase gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00837 BL14DL4_00838 BL14DL4_00838 aroQ aroQ 738825 739262 - 3-dehydroquinate dehydratase Catalyzes a trans-dehydration via an enolate intermediate%3B Belongs to the type-II 3-dehydroquinase family%3B KEGG: buh:BUAMB_375 3-dehydroquinate dehydratase II gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00838 BL14DL4_00839 BL14DL4_00839 BL14DL4_00839 739342 739878 - uncharacterized protein gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00839 BL14DL4_0084 BL14DL4_0084 BL14DL4_0084 68491 68682 - SPBc2 prophage-derived uncharacterized protein YonK gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0084 BL14DL4_00840 BL14DL4_00840 BL14DL4_00840 740130 741083 + uncharacterized protein gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00840 BL14DL4_00841 BL14DL4_00841 BL14DL4_00841 741122 741508 + uncharacterized protein gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00841 BL14DL4_00842 BL14DL4_00842 BL14DL4_00842 741505 742380 - uncharacterized protein Probable lipid hydrolase%3B Contains 1 patatin domain gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00842 BL14DL4_00843 BL14DL4_00843 BL14DL4_00843 742714 743142 - Transcriptional regulator MntR Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon%3B Contains 1 HTH dtxR-type DNA-binding domain gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00843 BL14DL4_00844 BL14DL4_00844 lplA lplA 743234 744070 - Lipoate--protein ligase Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH%2C an intermediate carrier during protein lipoylation%3B Belongs to the octanoyltransferase LipM family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU24530 lipoate-protein ligase A gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00844 BL14DL4_00845 BL14DL4_00845 glpE glpE 744257 744643 + Thiosulfate sulfurtransferase Contains 1 rhodanese domain%3B KEGG: pao:Pat9b_3716 thiosulfate sulfurtransferase gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00845 BL14DL4_00846 BL14DL4_00846 BL14DL4_00846 744809 745693 - Glycine betaine-binding protein OpuAC Involved in a multicomponent binding-protein-dependent transport system for glycine betaine gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00846 BL14DL4_00847 BL14DL4_00847 BL14DL4_00847 745693 746547 - Glycine betaine transport system permease protein OpuAB Involved in a multicomponent binding-protein-dependent transport system for glycine betain%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00847 BL14DL4_00848 BL14DL4_00848 proV proV 746547 747794 - Quaternary-amine-transporting ATPase Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: bli:BL01559 glycine betaine/proline transport system ATP-binding protein gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00848 BL14DL4_00849 BL14DL4_00849 BL14DL4_00849 748158 749615 - Glycine dehydrogenase (aminomethyl-transferring) The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. C-terminal subunit subfamily%3B KEGG: bli:BL01560 glycine dehydrogenase subunit 2 gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00849 BL14DL4_0085 BL14DL4_0085 BL14DL4_0085 69201 69716 - hypothetical protein gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0085 BL14DL4_00850 BL14DL4_00850 BL14DL4_00850 749608 750954 - Glycine dehydrogenase (aminomethyl-transferring) The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofacto%3B CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein%3B Belongs to the GcvP family. N-terminal subunit subfamily%3B KEGG: bsu:BSU24560 glycine dehydrogenase subunit 1 gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00850 BL14DL4_00851 BL14DL4_00851 gcvT gcvT 750985 752079 - Aminomethyltransferase The glycine cleavage system catalyzes the degradation of glycine%3B Belongs to the GcvT family%3B KEGG: tig:THII_2082 aminomethyltransferase gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00851 BL14DL4_00852 BL14DL4_00852 hepA hepA 752672 754351 + putative ATP-dependent helicase YqhH Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: eco:b0059 ATP-dependent helicase HepA%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00852 BL14DL4_00853 BL14DL4_00853 BL14DL4_00853 754358 755152 + uncharacterized protein gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00853 BL14DL4_00854 BL14DL4_00854 BL14DL4_00854 755343 755519 + Protein SinI Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE (By similarity)%3B Contains 1 Sin domain gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00854 BL14DL4_00855 BL14DL4_00855 BL14DL4_00855 755547 755888 + HTH-type transcriptional regulator SinR Affects autolysin level and flagellation. Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00855 BL14DL4_00856 BL14DL4_00856 BL14DL4_00856 755993 756787 - Spore coat-associated protein Belongs to the peptidase M73 family gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00856 BL14DL4_00857 BL14DL4_00857 sipW sipW 756861 757445 - Signal peptidase I Belongs to the peptidase S26B family%3B KEGG: bli:BL01564 signal peptidase%2C endoplasmic reticulum-type%3B Acting on peptide bonds (peptidases) gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00857 BL14DL4_00858 BL14DL4_00858 BL14DL4_00858 757442 758170 - uncharacterized protein gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00858 BL14DL4_00859 BL14DL4_00859 BL14DL4_00859 758447 758767 + uncharacterized protein gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00859 BL14DL4_0086 BL14DL4_0086 BL14DL4_0086 70338 70487 - hypothetical protein gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0086 BL14DL4_00860 BL14DL4_00860 BL14DL4_00860 758791 758973 - uncharacterized protein gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00860 BL14DL4_00861 BL14DL4_00861 BL14DL4_00861 759062 759427 - ComG operon protein Required for transformation and DNA binding gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00861 BL14DL4_00862 BL14DL4_00862 BL14DL4_00862 759440 759928 - ComG operon protein Required for transformation and DNA binding gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00862 BL14DL4_00863 BL14DL4_00863 BL14DL4_00863 760168 760614 - ComG operon protein Required for transformation and DNA binding gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00863 BL14DL4_00864 BL14DL4_00864 BL14DL4_00864 760611 760904 - ComG operon protein 3 like protein Required for transformation and DNA binding%3B Belongs to the ComGC family gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00864 BL14DL4_00865 BL14DL4_00865 BL14DL4_00865 760918 761952 - ComG operon protein Required for transformation and DNA binding%3B Belongs to the GSP F family gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00865 BL14DL4_00866 BL14DL4_00866 BL14DL4_00866 761942 763006 - ComG operon protein Required for uptake of DNA by competent cells%3B Belongs to the GSP E family gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00866 BL14DL4_00867 BL14DL4_00867 BL14DL4_00867 763163 764002 - RsbT co-antagonist protein RsbRB One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00867 BL14DL4_00868 BL14DL4_00868 BL14DL4_00868 764110 764181 + tRNA-Gln tRNA gene867 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00868 BL14DL4_00869 BL14DL4_00869 BL14DL4_00869 764244 764621 - Arsenate reductase (glutaredoxin) Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress%3B Belongs to the ArsC family%3B KEGG: bli:BL01574 arsenate reductase gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00869 BL14DL4_0087 BL14DL4_0087 BL14DL4_0087 70508 70783 - DNA-binding protein HU-1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it%2C and thus to prevent its denaturation under extreme environmental conditions%3B Belongs to the bacterial histone-like protein family gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0087 BL14DL4_00870 BL14DL4_00870 BL14DL4_00870 764830 765075 + uncharacterized protein gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00870 BL14DL4_00871 BL14DL4_00871 BL14DL4_00871 765113 765751 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: rha:RHA1_ro06903 hydroxyacylglutathione hydrolase gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00871 BL14DL4_00872 BL14DL4_00872 BL14DL4_00872 765907 766080 + uncharacterized protein gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00872 BL14DL4_00873 BL14DL4_00873 BL14DL4_00873 766141 766455 - UPF0045 protein YqgV Belongs to the UPF0045 family gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00873 BL14DL4_00874 BL14DL4_00874 BL14DL4_00874 766471 767580 - putative lipoprotein YqgU gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00874 BL14DL4_00875 BL14DL4_00875 yqgT yqgT 767635 768759 - Gamma-D-glutamyl-meso-diaminopimelate peptidase Belongs to the peptidase M14 family%3B KEGG: bli:BL01578 g-D-glutamyl-meso-diaminopimelate peptidase gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00875 BL14DL4_00876 BL14DL4_00876 BL14DL4_00876 768901 769848 - Iron(3+)-hydroxamate-binding protein FhuD Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00876 BL14DL4_00877 BL14DL4_00877 BL14DL4_00877 769845 769991 - hypothetical protein gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00877 BL14DL4_00878 BL14DL4_00878 ltaS ltaS 770017 771915 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Belongs to the LTA synthase family%3B KEGG: lrh:LGG_00830 lipoteichoic acid synthase gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00878 BL14DL4_00879 BL14DL4_00879 BL14DL4_00879 772097 773071 - Glucokinase Belongs to the ROK (NagC/XylR) family%3B KEGG: bli:BL01581 glucokinase gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00879 BL14DL4_0088 BL14DL4_0088 BL14DL4_0088 70894 71700 - hypothetical protein gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0088 BL14DL4_00880 BL14DL4_00880 BL14DL4_00880 773394 774848 - Stage V sporulation protein AF Belongs to the GerABKA family gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00880 BL14DL4_00881 BL14DL4_00881 gluP gluP 774925 776463 - Rhomboid protease Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter%3B Belongs to the peptidase S54 family%3B Contains 2 TPR repeats%3B KEGG: bli:BL03719 rhomboid protease GluP gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00881 BL14DL4_00882 BL14DL4_00882 BL14DL4_00882 776559 776732 - uncharacterized protein gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00882 BL14DL4_00883 BL14DL4_00883 BL14DL4_00883 776782 777309 - 5-formyltetrahydrofolate cyclo-ligase Belongs to the 5-formyltetrahydrofolate cyclo-ligase family%3B KEGG: bli:BL03718 5-formyltetrahydrofolate cyclo-ligase gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00883 BL14DL4_00884 BL14DL4_00884 BL14DL4_00884 777404 777553 - 50S ribosomal protein L33 Belongs to the ribosomal protein L33P family gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00884 BL14DL4_00885 BL14DL4_00885 BL14DL4_00885 777657 778769 - Glycogen(starch) synthase Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: dca:Desca_1720 glycogen(starch) synthase gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00885 BL14DL4_00886 BL14DL4_00886 BL14DL4_00886 778766 779263 - uncharacterized protein gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00886 BL14DL4_00887 BL14DL4_00887 BL14DL4_00887 779424 779789 + uncharacterized protein gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00887 BL14DL4_00888 BL14DL4_00888 BL14DL4_00888 779786 780265 + uncharacterized protein gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00888 BL14DL4_00889 BL14DL4_00889 pstB pstB 780357 781136 - Phosphate-transporting ATPase Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03715 phosphate transport system ATP-binding protein gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00889 BL14DL4_0089 BL14DL4_0089 BL14DL4_0089 71688 74465 - hypothetical protein gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0089 BL14DL4_00890 BL14DL4_00890 BL14DL4_00890 781149 781976 - Phosphate-transporting ATPase Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03714 phosphate transport system ATP-binding protein gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00890 BL14DL4_00891 BL14DL4_00891 BL14DL4_00891 781996 782883 - putative ABC transporter permease protein YqgI Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00891 BL14DL4_00892 BL14DL4_00892 BL14DL4_00892 782883 783812 - putative ABC transporter permease protein YqgH Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00892 BL14DL4_00893 BL14DL4_00893 BL14DL4_00893 783886 784803 - Phosphate-binding protein PstS Part of the ABC transporter complex PstSACB involved in phosphate import%3B Belongs to the PstS family gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00893 BL14DL4_00894 BL14DL4_00894 BL14DL4_00894 784997 787117 - uncharacterized protein Belongs to the transpeptidase family%3B KEGG: seq:SZO_13590 penicillin-binding protein 2B%3B Aminoacyltransferases gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00894 BL14DL4_00895 BL14DL4_00895 BL14DL4_00895 787219 788505 - uncharacterized protein gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00895 BL14DL4_00896 BL14DL4_00896 BL14DL4_00896 788685 789293 - Superoxide dismutase Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems%3B Belongs to the iron/manganese superoxide dismutase family%3B KEGG: bva:BVAF_021 superoxide dismutase%2C Fe-Mn family gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00896 BL14DL4_00897 BL14DL4_00897 BL14DL4_00897 789478 789960 - uncharacterized protein gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00897 BL14DL4_00898 BL14DL4_00898 BL14DL4_00898 790118 790876 + uncharacterized protein gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00898 BL14DL4_00899 BL14DL4_00899 BL14DL4_00899 790961 791266 + uncharacterized protein Contains 1 LysM repeat gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00899 BL14DL4_0090 BL14DL4_0090 BL14DL4_0090 74499 74939 - hypothetical protein gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0090 BL14DL4_00900 BL14DL4_00900 gcpE gcpE 791379 792491 + (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) Converts 2C-methyl-D-erythritol 2%2C4-cyclodiphosphate (ME-2%2C4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate%3B Belongs to the IspG family%3B KEGG: bsu:BSU25070 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00900 BL14DL4_00901 BL14DL4_00901 BL14DL4_00901 792530 792901 - uncharacterized protein gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00901 BL14DL4_00902 BL14DL4_00902 BL14DL4_00902 793017 793619 + Putative nucleotidase YqfW Belongs to the 5'(3')-deoxyribonucleotidase family gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00902 BL14DL4_00903 BL14DL4_00903 BL14DL4_00903 793690 794121 - Zinc-specific metallo-regulatory protein Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake%2C yciC and ycdHIyceA. Also represses the expression of rpmE2%2C the gene for ribosomal protein L31B%2C which is expressed only after the end of exponential growth%3B Belongs to the Fur family gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00903 BL14DL4_00904 BL14DL4_00904 BL14DL4_00904 794099 794959 - 29 kDa membrane protein in psaA 5'region Belongs to the ABC-3 integral membrane protein family gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00904 BL14DL4_00905 BL14DL4_00905 BL14DL4_00905 794959 795744 - Spermidine/putrescine import ATP-binding protein PotA Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00905 BL14DL4_00906 BL14DL4_00906 BL14DL4_00906 795879 796763 - UPF0750 membrane protein YqfU Belongs to the UPF0750 family gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00906 BL14DL4_00907 BL14DL4_00907 BL14DL4_00907 796887 797147 + uncharacterized protein gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00907 BL14DL4_00908 BL14DL4_00908 BL14DL4_00908 797175 798068 - Deoxyribonuclease IV Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin%3B Belongs to the AP endonuclease 2 family%3B KEGG: bsu:BSU25130 deoxyribonuclease IV gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00908 BL14DL4_00909 BL14DL4_00909 cshB cshB 798080 799399 - RNA helicase DEAD-box RNA helicase that plays a role in 70S ribosome assembly. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU25140 ATP-dependent RNA helicase CshB gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00909 BL14DL4_0091 BL14DL4_0091 BL14DL4_0091 75517 75927 - hypothetical protein gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0091 BL14DL4_00910 BL14DL4_00910 BL14DL4_00910 799656 800303 + uncharacterized protein gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00910 BL14DL4_00911 BL14DL4_00911 ispH ispH 800424 801368 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B Belongs to the IspH family%3B KEGG: bsu:BSU25160 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00911 BL14DL4_00912 BL14DL4_00912 BL14DL4_00912 801396 802517 - GTP cyclohydrolase 1 type 2 like protein Belongs to the GTP cyclohydrolase I type 2/NIF3 family gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00912 BL14DL4_00913 BL14DL4_00913 trmK trmK 802514 803227 - tRNA (adenine(22)-N(1))-methyltransferase Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 22 (m1A22) in tRNA%3B Belongs to the TrmK family%3B KEGG: bsq:B657_25180 tRNA (adenine22-N1)-methyltransferase gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00913 BL14DL4_00914 BL14DL4_00914 BL14DL4_00914 803598 803601 - Deoxyribonuclease V%3B nonfunctional due to frameshift pseudo gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00914 BL14DL4_00915 BL14DL4_00915 BL14DL4_00915 804255 804479 - hypothetical protein gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00915 BL14DL4_00916 BL14DL4_00916 BL14DL4_00916 804702 805352 - hypothetical protein gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00916 BL14DL4_00917 BL14DL4_00917 BL14DL4_00917 805630 806034 - hypothetical protein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00917 BL14DL4_00918 BL14DL4_00918 BL14DL4_00918 806115 806453 - hypothetical protein gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00918 BL14DL4_00919 BL14DL4_00919 BL14DL4_00919 806556 807065 - hypothetical protein gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00919 BL14DL4_0092 BL14DL4_0092 BL14DL4_0092 75941 76639 - hypothetical protein gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0092 BL14DL4_00920 BL14DL4_00920 BL14DL4_00920 807609 807633 - Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00920 BL14DL4_00921 BL14DL4_00921 BL14DL4_00921 807952 808461 - hypothetical protein gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00921 BL14DL4_00922 BL14DL4_00922 BL14DL4_00922 808478 810487 - Putative ribonuclease YwqJ Probable toxic component of a toxin-antitoxin (TA) module. The C-terminus may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YwqK%2C but not by antitoxins specific to other toxins with the LXG domain (By similarity)%3B Contains 1 LXG domain gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00922 BL14DL4_00923 BL14DL4_00923 BL14DL4_00923 810512 810775 - uncharacterized protein gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00923 BL14DL4_00924 BL14DL4_00924 BL14DL4_00924 810775 811209 - uncharacterized protein gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00924 BL14DL4_00925 BL14DL4_00925 BL14DL4_00925 811579 811938 - Cytochrome c-550 gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00925 BL14DL4_00926 BL14DL4_00926 BL14DL4_00926 812295 813416 - RNA polymerase sigma factor SigA Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth%3B Belongs to the sigma-70 factor family. RpoD/SigA subfamily gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00926 BL14DL4_00927 BL14DL4_00927 dnaG dnaG 813623 815446 - DNA primase RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication%3B Belongs to the DnaG primase family%3B Contains 1 Toprim domain%3B KEGG: noc:Noc_0044 DNA primase%3B Nucleotidyltransferases gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00927 BL14DL4_00928 BL14DL4_00928 BL14DL4_00928 815479 815970 - UPF0178 protein Belongs to the UPF0178 family gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00928 BL14DL4_00929 BL14DL4_00929 BL14DL4_00929 816235 817047 - Putative pyruvate%2C phosphate dikinase regulatory protein Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate%2C phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation%3B Belongs to the pyruvate%2C phosphate/water dikinase regulatory protein family. PDRP subfamily gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00929 BL14DL4_0093 BL14DL4_0093 aprE aprE 76750 77751 + Subtilisin Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bsy:I653_16335 subtilisin gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0093 BL14DL4_00930 BL14DL4_00930 BL14DL4_00930 817073 817672 - Transcriptional repressor CcpN Transcription repressor that binds to the promoter of gapB and pckA genes%2C preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes%3B Contains 2 CBS domains%3B Contains 1 HTH deoR-type DNA-binding domain gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00930 BL14DL4_00931 BL14DL4_00931 glyS glyS 817909 819948 - Glycine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pin:Ping_3726 glycyl-tRNA synthetase beta chain gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00931 BL14DL4_00932 BL14DL4_00932 glyQ glyQ 819941 820828 - Glycine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: wbr:WGLp593 glycyl-tRNA synthetase alpha chain gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00932 BL14DL4_00933 BL14DL4_00933 BL14DL4_00933 821160 821930 - DNA repair protein RecO Involved in DNA repair and RecF pathway recombination%3B Belongs to the RecO family gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00933 BL14DL4_00934 BL14DL4_00934 BL14DL4_00934 821968 822111 - uncharacterized protein gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00934 BL14DL4_00935 BL14DL4_00935 BL14DL4_00935 822273 823178 - GTPase Era An essential GTPase that binds both GDP and GTP%2C with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity). Binds both GDP and GTP. Complements an E. coli era disruption mutant%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Era GTPase family%3B Contains 1 Era-type G (guanine nucleotide-binding) domain%3B Contains 1 KH type-2 domain gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00935 BL14DL4_00936 BL14DL4_00936 BL14DL4_00936 823159 823569 - Cytidine deaminase This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL03673 cytidine deaminase gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00936 BL14DL4_00937 BL14DL4_00937 BL14DL4_00937 823701 824081 - Undecaprenol kinase Recycling of diacylglycerol produced during the turnover of membrane phospholipid%3B Belongs to the bacterial diacylglycerol kinase family%3B KEGG: bli:BL03672 undecaprenol kinase gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00937 BL14DL4_00938 BL14DL4_00938 BL14DL4_00938 824059 824535 - Endoribonuclease YbeY Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA%3B Belongs to the endoribonuclease YbeY family gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00938 BL14DL4_00939 BL14DL4_00939 BL14DL4_00939 824532 826682 - uncharacterized protein gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00939 BL14DL4_0094 BL14DL4_0094 BL14DL4_0094 78448 78885 - hypothetical protein gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0094 BL14DL4_00940 BL14DL4_00940 BL14DL4_00940 826751 827710 - PhoH-like protein Belongs to the PhoH family gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00940 BL14DL4_00941 BL14DL4_00941 BL14DL4_00941 827707 828903 - uncharacterized protein To B. megaterium SpoIV gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00941 BL14DL4_00942 BL14DL4_00942 BL14DL4_00942 828921 829202 - uncharacterized protein gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00942 BL14DL4_00943 BL14DL4_00943 BL14DL4_00943 829258 829707 - uncharacterized protein gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00943 BL14DL4_00944 BL14DL4_00944 BL14DL4_00944 829737 830729 - UPF0365 protein Belongs to the UPF0365 family gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00944 BL14DL4_00945 BL14DL4_00945 BL14DL4_00945 830753 832072 - uncharacterized protein gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00945 BL14DL4_00946 BL14DL4_00946 BL14DL4_00946 832217 832663 - uncharacterized protein gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00946 BL14DL4_00947 BL14DL4_00947 BL14DL4_00947 832678 832851 - 30S ribosomal protein S21 Belongs to the ribosomal protein S21P family gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00947 BL14DL4_00948 BL14DL4_00948 BL14DL4_00948 833037 833972 + uncharacterized protein To E. coli YjbB gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00948 BL14DL4_00949 BL14DL4_00949 deoC deoC 833992 834663 - Deoxyribose-phosphate aldolase Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bli:BL02102 deoxyribose-phosphate aldolase gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00949 BL14DL4_0095 BL14DL4_0095 BL14DL4_0095 79108 79632 + hypothetical protein gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0095 BL14DL4_00950 BL14DL4_00950 mtaB mtaB 834754 836109 - tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A)%2C leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine%3B Belongs to the methylthiotransferase family. MtaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU25430 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00950 BL14DL4_00951 BL14DL4_00951 rsmE rsmE 836112 836879 - 16S rRNA (uracil(1498)-N(3))-methyltransferase Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)%3B Belongs to the RNA methyltransferase RsmE family%3B KEGG: bli:BL02100 16S rRNA (uracil1498-N3)-methyltransferase gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00951 BL14DL4_00952 BL14DL4_00952 prmA prmA 836903 837838 - Ribosomal protein L11 methyltransferase Methylates ribosomal protein L11%3B Belongs to the methyltransferase superfamily. PrmA family%3B KEGG: bli:BL02099 ribosomal protein L11 methyltransferase%3B Methyltransferases gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00952 BL14DL4_00953 BL14DL4_00953 BL14DL4_00953 837862 838989 - Chaperone protein DnaJ Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C DnaK-independent fashion. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding. Also involved%2C together with DnaK and GrpE%2C in the DNA replication of plasmids through activation of initiation proteins%3B Belongs to the DnaJ family%3B Contains 1 CR-type zinc finger%3B Contains 1 J domain gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00953 BL14DL4_00954 BL14DL4_00954 BL14DL4_00954 839172 841010 - Chaperone protein DnaK Acts as a chaperone%3B Belongs to the heat shock protein 70 family gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00954 BL14DL4_00955 BL14DL4_00955 BL14DL4_00955 841034 841618 - Protein GrpE Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%2C in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to Dna%3B upon interaction with the DnaJ-bound protein%2C DnaK hydrolyzes its bound ATP%2C resulting in the formation of a stable complex. GrpE releases ADP from Dna%3B ATP binding to DnaK triggers the release of the substrate protein%2C thus completing the reaction cycle. Several rounds of ATP- dependent interactions between DnaJ%2C DnaK and GrpE are required for fully efficient folding%3B Belongs to the GrpE family gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00955 BL14DL4_00956 BL14DL4_00956 BL14DL4_00956 841697 842728 - Heat-inducible transcription repressor HrcA Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons%3B Belongs to the HrcA family gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00956 BL14DL4_00957 BL14DL4_00957 BL14DL4_00957 843702 843705 - Coproporphyrinogen dehydrogenase%3B nonfunctional due to frameshift pseudo gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00957 BL14DL4_00958 BL14DL4_00958 BL14DL4_00958 844007 845845 - Elongation factor Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction%2C by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex%2C thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00958 BL14DL4_00959 BL14DL4_00959 BL14DL4_00959 845991 846314 - uncharacterized protein gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00959 BL14DL4_0096 BL14DL4_0096 BL14DL4_0096 79876 80058 + SPBc2 prophage-derived uncharacterized protein YonT gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0096 BL14DL4_00960 BL14DL4_00960 BL14DL4_00960 846330 847535 - Stage II sporulation protein gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00960 BL14DL4_00961 BL14DL4_00961 BL14DL4_00961 847654 848760 - GPR endopeptidase Initiates the rapid degradation of small%2C acid-soluble proteins during spore germination%3B Belongs to the peptidase A25 family%3B KEGG: bli:BL02089 spore protease gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00961 BL14DL4_00962 BL14DL4_00962 BL14DL4_00962 848965 849231 + 30S ribosomal protein S20 Binds directly to 16S ribosomal RNA%3B Belongs to the ribosomal protein S20P family gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00962 BL14DL4_00963 BL14DL4_00963 holA holA 849293 850357 - DNA-directed DNA polymerase KEGG: bld:BLi02748 DNA polymerase III subunit delta gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00963 BL14DL4_00964 BL14DL4_00964 BL14DL4_00964 850566 850697 + putative membrane protein YqzM gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00964 BL14DL4_00965 BL14DL4_00965 BL14DL4_00965 850722 853109 - ComE operon protein The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding. To H. influenzae REC2%2C N. gonorrhoeae ComA and E. coli YcaI gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00965 BL14DL4_00966 BL14DL4_00966 BL14DL4_00966 853113 853682 - dCMP deaminase Dispensable for transformability. Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bsu:BSU25580 dCMP deaminase gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00966 BL14DL4_00967 BL14DL4_00967 BL14DL4_00967 853751 854380 - ComE operon protein Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect. Contains 2 HhH domains gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00967 BL14DL4_00968 BL14DL4_00968 BL14DL4_00968 854464 855285 + ComE operon protein Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase. Belongs to the pyrroline-5-carboxylate reductase family gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00968 BL14DL4_00969 BL14DL4_00969 ubiG ubiG 855355 856110 - 2-polyprenyl-6-hydroxyphenol methylase May be a S-adenosyl-L-methionine (SAM)-dependent methyltransferase. Belongs to the methyltransferase superfamily%3B KEGG: fil:BN1229_v1_1253 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00969 BL14DL4_0097 BL14DL4_0097 BL14DL4_0097 80370 81245 + hypothetical protein gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0097 BL14DL4_00970 BL14DL4_00970 BL14DL4_00970 856107 856463 - Ribosomal silencing factor RsfS Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN)%2C blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes%2C thus repressing translation%3B Belongs to the Iojap/RsfS family gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00970 BL14DL4_00971 BL14DL4_00971 BL14DL4_00971 856477 857040 - Nicotinate-nucleotide adenylyltransferase Contains 1 HD domain%3B KEGG: ccel:CCDG5_0474 nicotinate-nucleotide adenylyltransferase gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00971 BL14DL4_00972 BL14DL4_00972 BL14DL4_00972 857030 857599 - Nicotinate-nucleotide adenylyltransferase Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)%3B Belongs to the NadD family%3B KEGG: nma:NMA0416 nicotinate-nucleotide adenylyltransferase gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00972 BL14DL4_00973 BL14DL4_00973 BL14DL4_00973 857618 857908 - putative RNA-binding protein YqeI Contains 1 CRM domain gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00973 BL14DL4_00974 BL14DL4_00974 aroE aroE 857902 858738 - Shikimate dehydrogenase Involved in the biosynthesis of the chorismate%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)%3B Belongs to the shikimate dehydrogenase family%3B KEGG: bli:BL02079 shikimate dehydrogenase gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00974 BL14DL4_00975 BL14DL4_00975 BL14DL4_00975 858758 859858 - uncharacterized protein Binds GTP and GDP. Belongs to the TRAFAC class YlqF/YawG GTPase family%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00975 BL14DL4_00976 BL14DL4_00976 BL14DL4_00976 859862 860380 - uncharacterized protein gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00976 BL14DL4_00977 BL14DL4_00977 BL14DL4_00977 861006 861161 - hypothetical protein gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00977 BL14DL4_00978 BL14DL4_00978 BL14DL4_00978 861239 861970 - putative lipoprotein YqeF gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00978 BL14DL4_00979 BL14DL4_00979 BL14DL4_00979 862114 862875 - putative N-acetyltransferase YdfB Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK4362 null%3B Transferring groups other than amino-acyl groups gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00979 BL14DL4_0098 BL14DL4_0098 BL14DL4_0098 81235 82464 + SPBc2 prophage-derived uncharacterized protein YonV gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0098 BL14DL4_00980 BL14DL4_00980 BL14DL4_00980 862907 863281 - uncharacterized protein gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00980 BL14DL4_00981 BL14DL4_00981 BL14DL4_00981 863585 866524 + Formate dehydrogenase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bli:BL02109 formate dehydrogenase major subunit gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00981 BL14DL4_00982 BL14DL4_00982 BL14DL4_00982 866546 867025 + uncharacterized protein To A. fulgidus AF1717 gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00982 BL14DL4_00983 BL14DL4_00983 BL14DL4_00983 867101 867337 - hypothetical protein gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00983 BL14DL4_00984 BL14DL4_00984 BL14DL4_00984 867572 868297 + RNA polymerase sigma-K factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell. Belongs to the sigma-70 factor family gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00984 BL14DL4_00985 BL14DL4_00985 BL14DL4_00985 868592 869542 - hypothetical protein gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00985 BL14DL4_00986 BL14DL4_00986 BL14DL4_00986 870209 872014 - Subtilin transport ATP-binding protein SpaT Probably implicated in the export process of the lantibiotic subtilin. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00986 BL14DL4_00987 BL14DL4_00987 BL14DL4_00987 872266 872811 - hypothetical protein gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00987 BL14DL4_00988 BL14DL4_00988 BL14DL4_00988 872808 873338 - hypothetical protein gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00988 BL14DL4_00989 BL14DL4_00989 BL14DL4_00989 873542 874699 + Stage II sporulation protein gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00989 BL14DL4_0099 BL14DL4_0099 BL14DL4_0099 82819 83097 + hypothetical protein gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_0099 BL14DL4_00990 BL14DL4_00990 BL14DL4_00990 874714 874878 + hypothetical protein gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00990 BL14DL4_00991 BL14DL4_00991 BL14DL4_00991 875122 875343 - hypothetical protein gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00991 BL14DL4_00992 BL14DL4_00992 BL14DL4_00992 875665 875979 + RNA polymerase sigma-28 factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor directs the transcription of crystal protein genes%2C a sporulation-regulated event (By similarity)%3B Belongs to the sigma-70 factor family gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00992 BL14DL4_00993 BL14DL4_00993 BL14DL4_00993 876031 876561 - hypothetical protein gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00993 BL14DL4_00994 BL14DL4_00994 BL14DL4_00994 876644 877168 - putative N-acetyltransferase YuaI Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: tth:TTC0848 null%3B Transferring groups other than amino-acyl groups gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00994 BL14DL4_00995 BL14DL4_00995 BL14DL4_00995 878419 878793 - UPF0715 membrane protein YwlA Belongs to the UPF0715 family gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00995 BL14DL4_00996 BL14DL4_00996 BL14DL4_00996 878849 880198 + hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00996 BL14DL4_00997 BL14DL4_00997 BL14DL4_00997 880639 881949 - hypothetical protein gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00997 BL14DL4_00998 BL14DL4_00998 BL14DL4_00998 882611 883351 - hypothetical protein gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00998 BL14DL4_00999 BL14DL4_00999 BL14DL4_00999 883611 885044 - Hydroxyacylglutathione hydrolase Belongs to the UPF0033 family%3B Contains 1 rhodanese domain%3B KEGG: bst:GYO_2875 hydroxyacylglutathione hydrolase gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_00999 BL14DL4_01000 BL14DL4_01000 BL14DL4_01000 885117 886316 - Sulfide:quinone oxidoreductase%2C mitochondrial Catalyzes the oxidation of hydrogen sulfide%2C with the help of a quinone%3B Belongs to the SQRD family%3B KEGG: bst:GYO_2876 sulfide:quinone oxidoreductase%3B With a quinone or similar compound as acceptor gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01000 BL14DL4_01001 BL14DL4_01001 BL14DL4_01001 886477 887121 - Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01001 BL14DL4_01002 BL14DL4_01002 nreB nreB 887096 888151 - Histidine kinase Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation%2C at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bbe:BBR47_03990 two-component system%2C NarL family%2C sensor histidine kinase NreB gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01002 BL14DL4_01003 BL14DL4_01003 BL14DL4_01003 888173 888508 - Thioredoxin-like protein YdfQ Contains 1 thioredoxin domain gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01003 BL14DL4_01004 BL14DL4_01004 BL14DL4_01004 888530 889312 - UPF0721 transmembrane protein YrkJ Belongs to the UPF0721 family gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01004 BL14DL4_01005 BL14DL4_01005 tusA tusA 889367 889594 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01005 BL14DL4_01006 BL14DL4_01006 BL14DL4_01006 889626 890756 - Hydroxyacylglutathione hydrolase Contains 1 rhodanese domain%3B KEGG: mba:Mbar_A2729 hydroxyacylglutathione hydrolase gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01006 BL14DL4_01007 BL14DL4_01007 BL14DL4_01007 890857 891429 - UPF0033 protein YrkI Belongs to the UPF0033 family%3B KEGG: afe:Lferr_2187 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01007 BL14DL4_01008 BL14DL4_01008 BL14DL4_01008 891536 892018 - uncharacterized protein KEGG: gca:Galf_0318 tRNA 2-thiouridine synthesizing protein A%3B Sulfurtransferases gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01008 BL14DL4_01009 BL14DL4_01009 BL14DL4_01009 892181 892441 - Copper-sensing transcriptional repressor CsoR Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01009 BL14DL4_01010 BL14DL4_01010 BL14DL4_01010 892916 893512 - hypothetical protein gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01010 BL14DL4_01011 BL14DL4_01011 BL14DL4_01011 893557 894264 - uncharacterized protein gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01011 BL14DL4_01012 BL14DL4_01012 BL14DL4_01012 895632 896474 - hypothetical protein gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01012 BL14DL4_01013 BL14DL4_01013 BL14DL4_01013 896983 897228 - Putative membrane protein insertion efficiency factor Could be involved in insertion of integral membrane proteins into the membrane%3B Belongs to the UPF0161 family gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01013 BL14DL4_01014 BL14DL4_01014 BL14DL4_01014 897795 897899 - hypothetical protein gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01014 BL14DL4_01015 BL14DL4_01015 hxlB hxlB 898060 898617 - 6-phospho-3-hexuloisomerase Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate%3B Belongs to the SIS family. PHI subfamily%3B Contains 1 SIS domain%3B KEGG: blh:BaLi_c28990 6-phospho-3-hexuloisomerase gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01015 BL14DL4_01016 BL14DL4_01016 hxlA hxlA 898614 899246 - 3-hexulose-6-phosphate synthase Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate%3B Belongs to the HPS/KGPDC family. HPS subfamily%3B KEGG: eum:ECUMN_2963 3-hexulose-6-phosphate synthase gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01016 BL14DL4_01017 BL14DL4_01017 BL14DL4_01017 899434 899781 - HTH-type transcriptional activator HxlR Positive regulator of hxlAB expression. Contains 1 HTH hxlR-type DNA-binding domain gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01017 BL14DL4_01018 BL14DL4_01018 fad6 fad6 900075 901133 + Fatty acid desaturase Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids%3B Belongs to the fatty acid desaturase family%3B KEGG: bsu:BSU19180 omega-6 fatty acid desaturase (delta-12 desaturase)%3B With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01018 BL14DL4_01019 BL14DL4_01019 desK desK 901254 902366 + Histidine kinase Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: blh:BaLi_c29030 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01019 BL14DL4_01020 BL14DL4_01020 BL14DL4_01020 902384 902983 + Transcriptional regulatory protein DesR Member of the two-component regulatory system DesR/DesK%2C responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01020 BL14DL4_01021 BL14DL4_01021 BL14DL4_01021 903058 904107 - Thioredoxin-disulfide reductase Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bli:BL02042 thioredoxin reductase (NADPH) gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01021 BL14DL4_01022 BL14DL4_01022 BL14DL4_01022 904397 906019 + Nickel-binding periplasmic protein Involved in a nickel transport system%2C probably represents the nickel binder. Belongs to the bacterial solute-binding protein 5 family gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01022 BL14DL4_01023 BL14DL4_01023 BL14DL4_01023 906029 906973 + Putative oligopeptide transport system permease protein oppB2 Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for the translocation of the substrate across the membrane. Important for S. aureus growth and survival during the infection process (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01023 BL14DL4_01024 BL14DL4_01024 BL14DL4_01024 906970 907803 + Oligopeptide transport system permease protein OppC Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01024 BL14DL4_01025 BL14DL4_01025 nikD nikD 907819 908637 + Nickel-transporting ATPase Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL02421 nickel transport system ATP-binding protein gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01025 BL14DL4_01026 BL14DL4_01026 BL14DL4_01026 908661 909497 + putative ABC transporter ATP-binding protein YcbN Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01026 BL14DL4_01027 BL14DL4_01027 BL14DL4_01027 909810 910646 + putative HTH-type transcriptional regulator YdfL Contains 1 HTH merR-type DNA-binding domain gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01027 BL14DL4_01028 BL14DL4_01028 BL14DL4_01028 910703 912058 + Multidrug export protein MepA Multidrug resistance efflux protein%3B Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family. MepA subfamily gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01028 BL14DL4_01029 BL14DL4_01029 BL14DL4_01029 912372 913379 + HTH-type transcriptional regulator GadX Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA%2C gadB and gadC. Depending on the conditions (growth phase and medium)%2C can repress gadW (By similarity). Negatively regulates perA expression in acidic conditions and positively regulates it in alkaline conditions%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01029 BL14DL4_01030 BL14DL4_01030 BL14DL4_01030 913397 914191 + 3-oxoacyl-[acyl-carrier-protein] reductase Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3%2C4-Hexanedione%2C 2%2C3-Heptanedione and 1-Phenyl-1%2C2- propanedione as substrates. No reductase activity is displayed in vitro with steroids%2C retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation%2C leading to p53/TP53 stabilization and increased transcription activity%2C resulting in the accumulation of MDM2 and CDKN1A/p21%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pao:Pat9b_1844 3-oxoacyl-(acyl-carrier protein) reductase gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01030 BL14DL4_01031 BL14DL4_01031 phoN phoN 914303 916093 - Acid phosphatase Belongs to the class A bacterial acid phosphatase family%3B KEGG: sty:STY4519 acid phosphatase (class A) gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01031 BL14DL4_01032 BL14DL4_01032 pnbA pnbA 916367 917206 - Isoprenylcysteine alpha-carbonyl methylesterase ICME Catalyzes the demethylation of isoprenylcysteine methylesters. In vitro%2C is specific for N-acetyl-S-farnesyl-L- cysteine methyl ester (AFCme) and has low activity toward N- acetyl-S-geranyl-L-cysteine methyl ester (AGCme). Acts as a positive regulator of ABA signaling. May be involved in the demethylation and inactivation of isoprenylated negative regulators of abscisic acid (ABA) signaling. Carboxyl methylation is a reversible and potentially regulated step in the post- translational modification of prenylated proteins%3B Belongs to the AB hydrolase superfamily. Isoprenylcysteine methylesterase family%3B KEGG: pat:Patl_0510 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01032 BL14DL4_01033 BL14DL4_01033 BL14DL4_01033 917620 918855 - Cytochrome P450 Belongs to the cytochrome P450 family%3B KEGG: ban:BA_2627 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01033 BL14DL4_01034 BL14DL4_01034 BL14DL4_01034 919253 920140 - UPF0721 transmembrane protein YtnM Belongs to the UPF0721 family gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01034 BL14DL4_01035 BL14DL4_01035 BL14DL4_01035 920449 920829 + hypothetical protein gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01035 BL14DL4_01036 BL14DL4_01036 BL14DL4_01036 921031 921828 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi02826 3-oxoacyl-(acyl-carrier protein) reductase gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01036 BL14DL4_01037 BL14DL4_01037 BL14DL4_01037 921866 923899 - Fructan beta-fructosidase Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bsu:BSU27030 fructan beta-fructosidase gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01037 BL14DL4_01038 BL14DL4_01038 BL14DL4_01038 924020 924847 - Fructose permease IID component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIID domain gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01038 BL14DL4_01039 BL14DL4_01039 BL14DL4_01039 924869 925672 - Fructose permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport. Contains 1 PTS EIIC type-4 domain gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01039 BL14DL4_01040 BL14DL4_01040 levE levE 925691 926182 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator. Contains 1 PTS EIIB type-4 domain%3B KEGG: kox:KOX_13535 PTS system%2C fructose-specific IIB component gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01040 BL14DL4_01041 BL14DL4_01041 agaF agaF 926182 926619 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. LevD and LevE act as negative regulators of the levanase operon. They may be involved in a PTS-mediated phosphorylation of a regulator. Contains 1 PTS EIIA type-4 domain%3B KEGG: ece:Z4488 PTS system%2C N-acetylgalactosamine-specific IIA component gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01041 BL14DL4_01042 BL14DL4_01042 BL14DL4_01042 926821 929607 - Transcriptional regulatory protein LevR Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system%2C and sacA for levanase. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-4 domain%3B Contains 1 sigma-54 factor interaction domain gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01042 BL14DL4_01043 BL14DL4_01043 BL14DL4_01043 930005 930469 - uncharacterized protein gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01043 BL14DL4_01044 BL14DL4_01044 BL14DL4_01044 930590 930850 + uncharacterized protein gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01044 BL14DL4_01045 BL14DL4_01045 catA catA 930933 931583 - Chloramphenicol O-acetyltransferase This enzyme is an effector of chloramphenicol resistance in bacteria. Belongs to the chloramphenicol acetyltransferase family%3B KEGG: bli:BL03127 chloramphenicol O-acetyltransferase type A gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01045 BL14DL4_01046 BL14DL4_01046 adaA adaA 931800 932360 + Bifunctional transcriptional activator/DNA repair enzyme AdaA Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues. The methylation of AdaA by methylphosphotriesters in DNA leads to its activation as a transcriptional regulator that activates the transcription of the ada operon which consists of adaA and adaB%2C and of the adjacent gene alkA. Contains 1 HTH araC/xylS-type DNA-binding domain%3B KEGG: bli:BL05281 AraC family transcriptional regulator%2C regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase%3B Methyltransferases gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01046 BL14DL4_01047 BL14DL4_01047 adaB adaB 932365 932892 + Methylated-DNA--[protein]-cysteine S-methyltransferase Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs O6- methylguanine residues in alkylated DNA by a direct and irreversible transfer of the methyl group from the base to one of its own cysteine residues%3B Belongs to the MGMT family%3B KEGG: bli:BL00477 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01047 BL14DL4_01048 BL14DL4_01048 akr1 akr1 932926 933774 - Aldehyde reductase Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: nce:NCER_101329 aldehyde reductase gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01048 BL14DL4_01049 BL14DL4_01049 BL14DL4_01049 933804 935039 - putative MFS-type transporter YtbD Belongs to the major facilitator superfamily gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01049 BL14DL4_01050 BL14DL4_01050 BL14DL4_01050 935196 935573 + putative HTH-type transcriptional regulator YtcD Contains 1 HTH hxlR-type DNA-binding domain gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01050 BL14DL4_01051 BL14DL4_01051 pepE pepE 935593 936258 + Dipeptidase E Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids%3B Belongs to the peptidase S51 family%3B KEGG: bli:BL00475 dipeptidase E gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01051 BL14DL4_01052 BL14DL4_01052 hemD hemD 936569 937396 - Uroporphyrinogen-III synthase KEGG: bsu:BSU12230 uroporphyrinogen-III synthase gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01052 BL14DL4_01053 BL14DL4_01053 BL14DL4_01053 937504 938448 + hypothetical protein gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01053 BL14DL4_01054 BL14DL4_01054 BL14DL4_01054 938491 939447 - Iron(3+)-hydroxamate-binding protein YxeB Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01054 BL14DL4_01055 BL14DL4_01055 BL14DL4_01055 939525 940424 - HTH-type transcriptional regulator CfxR Trans-acting transcriptional regulator of RuBisCO genes (cfxLS) expression. Contains 1 HTH lysR-type DNA-binding domain gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01055 BL14DL4_01056 BL14DL4_01056 BL14DL4_01056 940545 941762 + putative transporter Belongs to the major facilitator superfamily gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01056 BL14DL4_01057 BL14DL4_01057 BL14DL4_01057 941911 942294 + hypothetical protein gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01057 BL14DL4_01058 BL14DL4_01058 BL14DL4_01058 942319 945543 - Unspecific monooxygenase Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of medium to long-chain fatty acids%2C with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 and omega-3 positions%2C in approximately equal proportions. Also displays a NADPH-dependent reductase activity in the C-terminal domain%2C which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N- terminal domain%3B In the N-terminal sectio%3B belongs to the cytochrome P450 family%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bli:BL02398 cytochrome P450 / NADPH-cytochrome P450 reductase gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01058 BL14DL4_01059 BL14DL4_01059 BL14DL4_01059 945578 946153 - HTH-type transcriptional repressor FatR Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate%2C linoleate and phytanate%2C thereby allowing transcription of the fatR-cypB operon%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01059 BL14DL4_01060 BL14DL4_01060 wprA wprA 946417 949560 - Cell wall-associated protease CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges%3B Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bld:BLi02850 cell wall-associated protease%3B Serine endopeptidases gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01060 BL14DL4_01061 BL14DL4_01061 BL14DL4_01061 949732 950337 - Demethylmenaquinone methyltransferase Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family%3B KEGG: age:AA314_00425 demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1%2C4-benzoquinol methylase gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01061 BL14DL4_01062 BL14DL4_01062 BL14DL4_01062 950614 950763 + hypothetical protein gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01062 BL14DL4_01063 BL14DL4_01063 BL14DL4_01063 951181 951330 - uncharacterized protein gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01063 BL14DL4_01064 BL14DL4_01064 BL14DL4_01064 951738 951971 - uncharacterized protein gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01064 BL14DL4_01065 BL14DL4_01065 mccB mccB 952060 953202 - Cystathionine gamma-lyase The enzymatic degradation of amino acids in cheese is believed to generate aroma compounds and therefore to be essential for flavor development. Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine but is also able to catalyze an alpha%2C gamma elimination. With methionine as a substrate%2C it produces volatile sulfur compounds which are important for flavor formation in Gouda cheese. Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02018 cystathionine gamma-lyase / homocysteine desulfhydrase gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01065 BL14DL4_01066 BL14DL4_01066 BL14DL4_01066 953204 954127 - Cysteine synthase Belongs to the cysteine synthase/cystathionine beta- synthase family gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01066 BL14DL4_01067 BL14DL4_01067 mtnN mtnN 954179 954874 - Adenosylhomocysteine nucleosidase Catalyzes the direct conversion of aminodeoxyfutalosine (AFL) into dehypoxanthine futalosine (DHFL) and adenine via the hydrolysis of the N-glycosidic bon%3B this reaction seems to represent an essential step in the menaquinone biosynthesis pathway in Campylobacter species. Also catalyzes the hydrolysis of 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Can also probably use S-adenosylhomocysteine (SAH) as substrate%2C leading to adenine and S-ribosylhomocysteine. These other activities highlight the tremendous versatility of the enzyme%2C which also plays key roles in S-adenosylmethionine recycling and in the biosynthesis of the quorum-sensing molecule autoinducer-2. Shows negligible activity with futalosine (FL) as substrate%3B Belongs to the PNP/UDP phosphorylase family%3B KEGG: pat:Patl_0518 adenosylhomocysteine nucleosidase gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01067 BL14DL4_01068 BL14DL4_01068 yrrT yrrT 954896 955537 - putative methyltransferase Could be a S-adenosyl-L-methionine-dependent methyltransferase%3B Belongs to the methyltransferase superfamily. YrrT family%3B KEGG: bsu:BSU27280 putative AdoMet-dependent methyltransferase%3B Methyltransferases gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01068 BL14DL4_01069 BL14DL4_01069 BL14DL4_01069 955727 955930 + uncharacterized protein gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01069 BL14DL4_01070 BL14DL4_01070 BL14DL4_01070 955969 956661 - putative membrane protein YrrS gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01070 BL14DL4_01071 BL14DL4_01071 BL14DL4_01071 956720 958474 - Penicillin-binding protein 4B Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01071 BL14DL4_01072 BL14DL4_01072 BL14DL4_01072 958529 959005 - Transcription elongation factor GreA Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides%3B Belongs to the GreA/GreB family gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01072 BL14DL4_01073 BL14DL4_01073 BL14DL4_01073 959245 959880 - Uridine kinase Belongs to the uridine kinase family%3B KEGG: bli:BL02025 uridine kinase gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01073 BL14DL4_01074 BL14DL4_01074 BL14DL4_01074 959885 961153 - putative protease YrrO Belongs to the peptidase U32 family%3B KEGG: bli:BL02026 putative protease%3B Acting on peptide bonds (peptidases) gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01074 BL14DL4_01075 BL14DL4_01075 BL14DL4_01075 961168 962097 - putative protease YrrN Belongs to the peptidase U32 family%3B KEGG: bsu:BSU27350 putative protease%3B Acting on peptide bonds (peptidases) gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01075 BL14DL4_01076 BL14DL4_01076 BL14DL4_01076 962094 962756 - Caffeoyl-CoA O-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family%3B KEGG: ctc:CTC01062 caffeoyl-CoA O-methyltransferase gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01076 BL14DL4_01077 BL14DL4_01077 BL14DL4_01077 962904 964016 - UPF0755 protein YrrL Belongs to the UPF0755 family gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01077 BL14DL4_01078 BL14DL4_01078 BL14DL4_01078 964211 964495 - UPF0473 protein Belongs to the UPF0473 family gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01078 BL14DL4_01079 BL14DL4_01079 ruvX ruvX 964506 964925 - Putative pre-16S rRNA nuclease Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA%3B Belongs to the YqgF nuclease family%3B KEGG: dao:Desac_2916 putative holliday junction resolvase%3B Acting on ester bonds gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01079 BL14DL4_01080 BL14DL4_01080 BL14DL4_01080 964932 965198 - UPF0297 protein Belongs to the UPF0297 family%3B KEGG: snu:SPNA45_01835 putative holliday junction resolvase%3B Acting on ester bonds gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01080 BL14DL4_01081 BL14DL4_01081 aarS aarS 965282 967918 - Alanine--tRNA ligase Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: dno:DNO_0286 alanyl-tRNA synthetase gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01081 BL14DL4_01082 BL14DL4_01082 BL14DL4_01082 968269 969327 - UPF0118 membrane protein YrrI Belongs to the UPF0118 (PerM) family gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01082 BL14DL4_01083 BL14DL4_01083 BL14DL4_01083 969565 969756 - uncharacterized protein gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01083 BL14DL4_01084 BL14DL4_01084 BL14DL4_01084 969772 970236 - uncharacterized protein gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01084 BL14DL4_01085 BL14DL4_01085 recD recD 970325 972721 - Exodeoxyribonuclease V DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs%2C requires at least 10 bases of 5'-ssDNA for helicase activity%3B Belongs to the RecD family. RecD-like subfamily%3B KEGG: bli:BL02037 exodeoxyribonuclease V alpha subunit gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01085 BL14DL4_01086 BL14DL4_01086 BL14DL4_01086 972772 973422 - TPR repeat-containing protein YrrB Could be an interacting mediator in the complex formation among RNA sulfuration components%2C RNA processing components%2C and aminoacyl-tRNA synthetases. Contains 6 TPR repeats gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01086 BL14DL4_01087 BL14DL4_01087 mnmA mnmA 973516 974634 - tRNA-specific 2-thiouridylase MnmA Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA%2C leading to the formation of s(2)U34%3B Belongs to the MnmA/TRMU family%3B KEGG: azl:AZL_020120 tRNA-specific 2-thiouridylase%3B Sulfurtransferases gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01087 BL14DL4_01088 BL14DL4_01088 iscS iscS 974740 975879 - Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: tti:THITH_16475 cysteine desulfurase gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01088 BL14DL4_01089 BL14DL4_01089 BL14DL4_01089 975900 976316 - HTH-type transcriptional regulator CymR Master repressor of cysteine metabolism in B. subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK)%2C sulfonates (ssu)%2C or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulated by CysK in response to cysteine availability. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01089 BL14DL4_01090 BL14DL4_01090 BL14DL4_01090 976826 978091 + putative AAA domain-containing protein YrvN Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01090 BL14DL4_01091 BL14DL4_01091 BL14DL4_01091 978172 978936 - tRNA threonylcarbamoyladenosine dehydratase Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine%3B Belongs to the HesA/MoeB/ThiF family gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01091 BL14DL4_01092 BL14DL4_01092 darS darS 979356 981134 - Aspartate--tRNA ligase Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)%3B Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27550 aspartyl-tRNA synthetase gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01092 BL14DL4_01093 BL14DL4_01093 harS harS 981149 982423 - Histidine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU27560 histidyl-tRNA synthetase gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01093 BL14DL4_01094 BL14DL4_01094 BL14DL4_01094 982798 982962 - uncharacterized protein gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01094 BL14DL4_01095 BL14DL4_01095 BL14DL4_01095 983105 984676 + N-acetylmuramoyl-L-alanine amidase Probably involved in cell-wall metabolism%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL01120 N-acetylmuramoyl-L-alanine amidase gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01095 BL14DL4_01096 BL14DL4_01096 dtd1 dtd1 984704 985147 - D-aminoacyl-tRNA deacylase D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules%2C this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo%3B Belongs to the DTD family%3B KEGG: sml:Smlt4166 D-tyrosyl-tRNA(Tyr) deacylase%3B Acting on ester bonds gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01096 BL14DL4_01097 BL14DL4_01097 relA relA 985161 987362 - GTP diphosphokinase In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp (By similarity)%3B Belongs to the RelA/SpoT family%3B Contains 1 ACT domain%3B Contains 1 HD domain%3B KEGG: bsu:BSU27600 GTP pyrophosphokinase gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01097 BL14DL4_01098 BL14DL4_01098 aprT aprT 987533 988045 - Adenine phosphoribosyltransferase Catalyzes a salvage reaction resulting in the formation of AMP%2C that is energically less costly than de novo synthesis%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bli:BL01126 adenine phosphoribosyltransferase gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01098 BL14DL4_01099 BL14DL4_01099 BL14DL4_01099 988063 990411 - Single-stranded-DNA-specific exonuclease RecJ Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB%3B Belongs to the RecJ family%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU27620 single-stranded-DNA-specific exonuclease%3B Acting on ester bonds gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01099 BL14DL4_01100 BL14DL4_01100 BL14DL4_01100 990483 990776 - uncharacterized protein gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01100 BL14DL4_01101 BL14DL4_01101 BL14DL4_01101 990930 993155 - Protein translocase subunit SecDF Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane%3B Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)%3B In the N-terminal sectio%3B belongs to the SecD/SecF family. SecD subfamily%3B In the C-terminal sectio%3B belongs to the SecD/SecF family. SecF subfamily gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01101 BL14DL4_01102 BL14DL4_01102 BL14DL4_01102 993192 993488 - Post-transcriptional regulator ComN Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01102 BL14DL4_01103 BL14DL4_01103 BL14DL4_01103 993606 995159 + Stage V sporulation protein Involved%2C directly or indirectly%2C in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes. Belongs to the polysaccharide synthase family gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01103 BL14DL4_01104 BL14DL4_01104 BL14DL4_01104 995168 995818 - UPF0702 transmembrane protein YrbG Belongs to the UPF0702 family gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01104 BL14DL4_01105 BL14DL4_01105 BL14DL4_01105 995974 996357 + putative membrane protein YrzE gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01105 BL14DL4_01106 BL14DL4_01106 BL14DL4_01106 996554 996814 - UPF0092 membrane protein Belongs to the UPF0092 family gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01106 BL14DL4_01107 BL14DL4_01107 BL14DL4_01107 996864 998009 - tRNA-guanine(34) transglycosylase Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr). After this exchange%2C a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine%2C resulting in the hypermodified nucleoside queuosine (Q) (7-(((4%2C5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)%3B Belongs to the queuine tRNA-ribosyltransferase family%3B KEGG: bsu:BSU27710 queuine tRNA-ribosyltransferase gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01107 BL14DL4_01108 BL14DL4_01108 queA queA 998038 999066 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)%3B Belongs to the QueA family%3B KEGG: atu:Atu1678 S-adenosylmethionine:tRNA ribosyltransferase-isomerase gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01108 BL14DL4_01109 BL14DL4_01109 ruvB ruvB 999107 999307 - DNA helicase KEGG: bamp:B938_12840 holliday junction DNA helicase RuvB gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01109 BL14DL4_01110 BL14DL4_01110 BL14DL4_01110 999300 1000304 - DNA helicase RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing%3B Belongs to the RuvB family%3B KEGG: bsu:BSU27730 holliday junction DNA helicase RuvB gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01110 BL14DL4_01111 BL14DL4_01111 ruvA ruvA 1000314 1000919 - DNA helicase RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates%2C in the presence of DNA%2C the weak ATPase activity of RuvB%3B Belongs to the RuvA family%3B KEGG: bsu:BSU27740 holliday junction DNA helicase RuvA gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01111 BL14DL4_01112 BL14DL4_01112 BL14DL4_01112 1001042 1001563 - Protein BofC gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01112 BL14DL4_01113 BL14DL4_01113 BL14DL4_01113 1001806 1002456 + Putative serine/threonine-protein kinase YrzF Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bcz:BCZK2452 null%3B Phosphotransferases with an alcohol group as acceptor gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01113 BL14DL4_01114 BL14DL4_01114 BL14DL4_01114 1002527 1002649 + hypothetical protein gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01114 BL14DL4_01115 BL14DL4_01115 BL14DL4_01115 1002734 1002913 - Small%2C acid-soluble spore protein Belongs to the SspH family gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01115 BL14DL4_01116 BL14DL4_01116 BL14DL4_01116 1003009 1003473 - uncharacterized protein Belongs to the DinB family gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01116 BL14DL4_01117 BL14DL4_01117 BL14DL4_01117 1003534 1004244 - UPF0714 protein YjqB Belongs to the UPF0714 family gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01117 BL14DL4_01118 BL14DL4_01118 BL14DL4_01118 1004658 1004837 + uncharacterized protein gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01118 BL14DL4_01119 BL14DL4_01119 BL14DL4_01119 1004929 1005255 - hypothetical protein gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01119 BL14DL4_01120 BL14DL4_01120 glgC glgC 1005403 1006125 - Glucose-1-phosphate adenylyltransferase Belongs to the TACO1 family%3B KEGG: pmf:P9303_05381 glucose-1-phosphate adenylyltransferase gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01120 BL14DL4_01121 BL14DL4_01121 BL14DL4_01121 1006252 1006887 - Sporulation cortex protein CoxA gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01121 BL14DL4_01122 BL14DL4_01122 BL14DL4_01122 1007060 1008112 - Spore coat assembly protein ExsA Required for the normal assembly and anchoring of both the spore coat and the exosporium layers%3B Contains 1 LysM repeat%3B To B. subtilis SafA gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01122 BL14DL4_01123 BL14DL4_01123 nadA nadA 1008228 1009337 - Quinolinate synthase Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate%3B Belongs to the quinolinate synthase A family. Type 3 subfamily%3B KEGG: bli:BL01153 quinolinate synthase gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01123 BL14DL4_01124 BL14DL4_01124 nadC nadC 1009359 1010198 - Nicotinate-nucleotide diphosphorylase (carboxylating) Involved in the catabolism of quinolinic acid (QA)%3B Belongs to the NadC/ModD family%3B KEGG: bli:BL01154 nicotinate-nucleotide pyrophosphorylase (carboxylating) gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01124 BL14DL4_01125 BL14DL4_01125 nadB nadB 1010179 1011753 - L-aspartate oxidase Catalyzes the oxidation of L-aspartate to iminoaspartate. Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily%3B KEGG: bli:BL01155 L-aspartate oxidase gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01125 BL14DL4_01126 BL14DL4_01126 BL14DL4_01126 1011854 1013032 + Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis (PubMed:8444804)%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: ppf:Pput_1517 cysteine desulfurase gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01126 BL14DL4_01127 BL14DL4_01127 BL14DL4_01127 1013001 1013543 + Transcription repressor NadR In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene%2C probably regulating it as well. May bind nicotinic acid gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01127 BL14DL4_01128 BL14DL4_01128 BL14DL4_01128 1013587 1014456 - Prephenate dehydratase Contains 1 ACT domain%3B Contains 1 prephenate dehydratase domain%3B KEGG: bld:BLi02917 prephenate dehydratase gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01128 BL14DL4_01129 BL14DL4_01129 pheB pheB 1014465 1014908 - Chorismate mutase Belongs to the UPF0735 family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU27910 chorismate mutase gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01129 BL14DL4_01130 BL14DL4_01130 BL14DL4_01130 1015022 1016308 - GTPase Obg An essential GTPase which binds GTP%2C GDP and possibly (p)ppGpp with moderate affinity%2C with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle%2C stress response%2C ribosome biogenesis and in those bacteria that undergo differentiation%2C in morphogenesis control%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01130 BL14DL4_01131 BL14DL4_01131 BL14DL4_01131 1016341 1016919 - Sporulation initiation phosphotransferase KEGG: bli:BL01158 stage 0 sporulation protein B (sporulation initiation phosphotransferase)%3B Transferring phosphorus-containing groups gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01131 BL14DL4_01132 BL14DL4_01132 BL14DL4_01132 1017145 1017426 - 50S ribosomal protein L27 Belongs to the ribosomal protein L27P family gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01132 BL14DL4_01133 BL14DL4_01133 BL14DL4_01133 1017439 1017780 - uncharacterized protein To M. genitalium MG233 gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01133 BL14DL4_01134 BL14DL4_01134 BL14DL4_01134 1017793 1018101 - 50S ribosomal protein L21 This protein binds to 23S rRNA in the presence of protein L20%3B Belongs to the ribosomal protein L21P family gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01134 BL14DL4_01135 BL14DL4_01135 BL14DL4_01135 1018258 1019124 - Stage IV sporulation protein FB Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro- sigma K factor. Belongs to the peptidase M50B family%3B KEGG: bli:BL05293 stage IV sporulation protein FB%3B Metalloendopeptidases gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01135 BL14DL4_01136 BL14DL4_01136 BL14DL4_01136 1019117 1019908 - Stage IV sporulation protein FA gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01136 BL14DL4_01137 BL14DL4_01137 BL14DL4_01137 1020054 1020482 + uncharacterized protein Belongs to the AHA1 family gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01137 BL14DL4_01138 BL14DL4_01138 BL14DL4_01138 1020482 1020802 + Transcriptional repressor SdpR Represses the transcription of the sdpIR operon and of several other operons that probably contribute to delaying commitment to sporulation%3B Contains 1 HTH arsR-type DNA-binding domain gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01138 BL14DL4_01139 BL14DL4_01139 BL14DL4_01139 1020847 1021653 - Septum site-determining protein MinD ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity)%3B Belongs to the ParA family. MinD subfamily gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01139 BL14DL4_01140 BL14DL4_01140 BL14DL4_01140 1021656 1022378 - putative septum site-determining protein MinC Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization%3B Belongs to the MinC family gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01140 BL14DL4_01141 BL14DL4_01141 BL14DL4_01141 1022391 1022909 - Rod shape-determining protein MreD Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity)%3B Belongs to the MreD family gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01141 BL14DL4_01142 BL14DL4_01142 BL14DL4_01142 1022906 1023814 - Cell shape-determining protein MreC Involved in formation and maintenance of cell shape%3B Belongs to the MreC family gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01142 BL14DL4_01143 BL14DL4_01143 BL14DL4_01143 1023845 1024855 - Rod shape-determining protein MreB Involved in formation of the rod shape of the cell%3B Belongs to the FtsA/MreB family gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01143 BL14DL4_01144 BL14DL4_01144 BL14DL4_01144 1024943 1025617 - UPF0758 protein Belongs to the UPF0758 family gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01144 BL14DL4_01145 BL14DL4_01145 BL14DL4_01145 1025672 1026244 - Septum formation protein Maf Involved in septum formation%3B Belongs to the maf family gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01145 BL14DL4_01146 BL14DL4_01146 BL14DL4_01146 1026398 1027429 - Stage II sporulation protein Involved in endospore development. Contains 1 SPOR domain gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01146 BL14DL4_01147 BL14DL4_01147 comC comC 1027633 1028382 - Type 4 prepilin-like protein leader peptide-processing enzyme Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue%3B Belongs to the peptidase A24 family%3B KEGG: bli:BL00633 leader peptidase (prepilin peptidase) / N-methyltransferase%3B Prepilin peptidase gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01147 BL14DL4_01148 BL14DL4_01148 folC folC 1028525 1029829 - Dihydrofolate synthase Can complement an H. volcanii mutant strain that is thymidine auxotroph because it lacks the two dihydrofolate reductase genes encoded by hdrA and hdrB%3B In the N-terminal sectio%3B belongs to the folylpolyglutamate synthase family%3B In the C-terminal sectio%3B belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bld:BLi02937 dihydrofolate synthase / folylpolyglutamate synthase gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01148 BL14DL4_01149 BL14DL4_01149 varS varS 1029905 1032547 - Valine--tRNA ligase Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine%2C to avoid such errors%2C it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner%3B Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily%3B KEGG: rpi:Rpic_2441 valyl-tRNA synthetase gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01149 BL14DL4_01150 BL14DL4_01150 BL14DL4_01150 1033009 1033200 + putative membrane protein YszA gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01150 BL14DL4_01151 BL14DL4_01151 BL14DL4_01151 1033220 1034242 - uncharacterized protein gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01151 BL14DL4_01152 BL14DL4_01152 BL14DL4_01152 1034270 1035727 - Stage VI sporulation protein D gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01152 BL14DL4_01153 BL14DL4_01153 hemL hemL 1035876 1037171 - Glutamate-1-semialdehyde 2%2C1-aminomutase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bsu:BSU28120 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01153 BL14DL4_01154 BL14DL4_01154 hemB hemB 1037197 1038171 - Porphobilinogen synthase Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit%2C each at a distinct site%2C and catalyzes their condensation to form porphobilinogen (By similarity)%3B Belongs to the ALAD family%3B KEGG: bli:BL00627 porphobilinogen synthase gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01154 BL14DL4_01155 BL14DL4_01155 BL14DL4_01155 1038175 1038966 - Uroporphyrinogen-III synthase May catalyze sequential reactions to synthesize uroporphyrinogen III from hydroxymethylbilane (HMB) and then precorrin-2%2C which are intermediate compounds in both vitamin B12 and siroheme biosyntheses%3B In the N-terminal sectio%3B belongs to the precorrin methyltransferase family%3B In the C-terminal sectio%3B belongs to the uroporphyrinogen-III synthase family%3B KEGG: bli:BL00626 uroporphyrinogen-III synthase gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01155 BL14DL4_01156 BL14DL4_01156 hemC hemC 1038956 1039897 - Hydroxymethylbilane synthase Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps%3B Belongs to the HMBS family%3B KEGG: bli:BL00625 hydroxymethylbilane synthase gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01156 BL14DL4_01157 BL14DL4_01157 BL14DL4_01157 1039937 1040767 - Protein HemX Required for HemL synthesis. To M. leprae U1620K gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01157 BL14DL4_01158 BL14DL4_01158 hemA hemA 1040773 1042158 - Glutamyl-tRNA reductase Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)%3B Belongs to the glutamyl-tRNA reductase family%3B KEGG: bay:RBAM_025230 glutamyl-tRNA reductase gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01158 BL14DL4_01159 BL14DL4_01159 BL14DL4_01159 1042323 1042808 + putative membrane protein YsxD gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01159 BL14DL4_01160 BL14DL4_01160 BL14DL4_01160 1042856 1043443 - putative GTP-binding protein EngB Necessary for normal cell division and for the maintenance of normal septation%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. EngB GTPase family%3B Contains 1 EngB-type G (guanine nucleotide-binding) domain gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01160 BL14DL4_01161 BL14DL4_01161 BL14DL4_01161 1043440 1045764 - Endopeptidase La ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner%3B Belongs to the peptidase S16 family%3B Contains 1 Lon domain%3B KEGG: bli:BL00621 ATP-dependent Lon protease gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01161 BL14DL4_01162 BL14DL4_01162 lonB lonB 1045983 1047638 - Lon protease ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Binds to DNA in a double-stranded%2C site-specific manner (By similarity)%3B Belongs to the peptidase S16 family%3B KEGG: bli:BL00620 Lon-like ATP-dependent protease%3B Serine endopeptidases gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01162 BL14DL4_01163 BL14DL4_01163 BL14DL4_01163 1047821 1049086 - ATP-dependent Clp protease ATP-binding subunit ClpX ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP%3B Belongs to the ClpX chaperone family gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01163 BL14DL4_01164 BL14DL4_01164 BL14DL4_01164 1049355 1050629 - Trigger factor Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase%3B Belongs to the FKBP-type PPIase family. Tig subfamily%3B Contains 1 PPIase FKBP-type domain gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01164 BL14DL4_01165 BL14DL4_01165 BL14DL4_01165 1050856 1051863 - TPR repeat-containing protein YsoA Contains 3 TPR repeats gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01165 BL14DL4_01166 BL14DL4_01166 leuD leuD 1051993 1052592 - 3-isopropylmalate dehydratase Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the LeuD family. LeuD type 1 subfamily%3B KEGG: bli:BL00615 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01166 BL14DL4_01167 BL14DL4_01167 leuC leuC 1052605 1054023 - 3-isopropylmalate dehydratase Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate%2C via the formation of 2-isopropylmaleate%3B Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily%3B KEGG: bsu:BSU28260 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01167 BL14DL4_01168 BL14DL4_01168 leuB leuB 1054057 1055169 - 3-isopropylmalate dehydrogenase Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate%3B Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily%3B KEGG: xft:PD1397 3-isopropylmalate dehydrogenase gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01168 BL14DL4_01169 BL14DL4_01169 leuA leuA 1055197 1056753 - 2-isopropylmalate synthase Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)%3B Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily%3B KEGG: dgg:DGI_2503 2-isopropylmalate synthase gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01169 BL14DL4_01170 BL14DL4_01170 ilvC ilvC 1056740 1057768 - Ketol-acid reductoisomerase (NADP(+)) Belongs to the ketol-acid reductoisomerase family%3B KEGG: bsu:BSU28290 ketol-acid reductoisomerase gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01170 BL14DL4_01171 BL14DL4_01171 ilvH ilvH 1057792 1058310 - Acetolactate synthase Belongs to the acetolactate synthase small subunit family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU28300 acetolactate synthase I/III small subunit gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01171 BL14DL4_01172 BL14DL4_01172 ilvB ilvB 1058307 1060031 - Acetolactate synthase Belongs to the TPP enzyme family%3B KEGG: bsu:BSU28310 acetolactate synthase I/II/III large subunit gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01172 BL14DL4_01173 BL14DL4_01173 ilvE ilvE 1060454 1061368 - Branched-chain-amino-acid transaminase Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL00607 branched-chain amino acid aminotransferase gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01173 BL14DL4_01174 BL14DL4_01174 BL14DL4_01174 1061822 1062052 + hypothetical protein gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01174 BL14DL4_01175 BL14DL4_01175 gdhA gdhA 1062095 1063477 - Glutamate dehydrogenase (NADP(+)) Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia%3B Belongs to the Glu/Leu/Phe/Val dehydrogenases family%3B KEGG: bli:BL00756 glutamate dehydrogenase (NADP+) gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01175 BL14DL4_01176 BL14DL4_01176 BL14DL4_01176 1063890 1064144 + hypothetical protein gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01176 BL14DL4_01177 BL14DL4_01177 BL14DL4_01177 1064188 1064679 - PERQ amino acid-rich with GYF domain-containing protein May play a role in tyrosine kinase receptor signaling regulation%3B Belongs to the PERQ family%3B Contains 1 GYF domain gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01177 BL14DL4_01178 BL14DL4_01178 BL14DL4_01178 1065115 1065330 - Phage-like element PBSX protein XkdE Belongs to the phage portal family. PBSX subfamily gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01178 BL14DL4_01179 BL14DL4_01179 BL14DL4_01179 1065493 1066629 - PBSX phage terminase large subunit Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01179 BL14DL4_01180 BL14DL4_01180 BL14DL4_01180 1066626 1067486 - hypothetical protein gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01180 BL14DL4_01181 BL14DL4_01181 BL14DL4_01181 1067533 1067781 - hypothetical protein gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01181 BL14DL4_01182 BL14DL4_01182 BL14DL4_01182 1067909 1068835 - DNA (cytosine-5-)-methyltransferase This methylase recognizes the double-stranded sequence GTGCAC%2C causes specific methylation on C-? on both strands%2C and protects the DNA from cleavage by the ApaLI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bst:GYO_0220 DNA (cytosine-5)-methyltransferase 1 gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01182 BL14DL4_01183 BL14DL4_01183 BL14DL4_01183 1068946 1069302 - hypothetical protein gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01183 BL14DL4_01184 BL14DL4_01184 BL14DL4_01184 1069333 1069620 - hypothetical protein gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01184 BL14DL4_01185 BL14DL4_01185 BL14DL4_01185 1069778 1070239 - hypothetical protein gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01185 BL14DL4_01186 BL14DL4_01186 BL14DL4_01186 1070347 1070802 - hypothetical protein gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01186 BL14DL4_01187 BL14DL4_01187 BL14DL4_01187 1070819 1072738 - Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01187 BL14DL4_01188 BL14DL4_01188 BL14DL4_01188 1072933 1074123 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bpu:BPUM_3641 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01188 BL14DL4_01189 BL14DL4_01189 BL14DL4_01189 1074120 1074251 + hypothetical protein gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01189 BL14DL4_01190 BL14DL4_01190 BL14DL4_01190 1074346 1074594 - hypothetical protein gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01190 BL14DL4_01191 BL14DL4_01191 BL14DL4_01191 1074843 1074992 - hypothetical protein gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01191 BL14DL4_01192 BL14DL4_01192 BL14DL4_01192 1075108 1075184 - tRNA-Arg tRNA gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01192 BL14DL4_01193 BL14DL4_01193 BL14DL4_01193 1075304 1075825 - Putative metallophosphoesterase YsnB Belongs to the metallophosphoesterase superfamily. YfcE family gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01193 BL14DL4_01194 BL14DL4_01194 rdgB rdgB 1075842 1076432 - XTP/dITP diphosphatase Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP/dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool%2C thus preventing their incorporation into DNA and avoiding chromosomal lesions%3B Belongs to the HAM1 NTPase family%3B KEGG: gme:Gmet_1875 XTP/dITP diphosphohydrolase gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01194 BL14DL4_01195 BL14DL4_01195 BL14DL4_01195 1076454 1077194 - tRNA nucleotidyltransferase Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates%3B Belongs to the RNase PH family%3B KEGG: bli:BL00312 ribonuclease PH gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01195 BL14DL4_01196 BL14DL4_01196 BL14DL4_01196 1077320 1078429 - Spore germination protein GerM gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01196 BL14DL4_01197 BL14DL4_01197 murI murI 1078581 1079396 - Glutamate racemase Provides the (R)-glutamate required for cell wall biosynthesis%3B Belongs to the aspartate/glutamate racemases family%3B KEGG: bsu:BSU28390 glutamate racemase gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01197 BL14DL4_01198 BL14DL4_01198 BL14DL4_01198 1079407 1079850 - putative HTH-type transcriptional regulator YsmB Contains 1 HTH marR-type DNA-binding domain gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01198 BL14DL4_01199 BL14DL4_01199 BL14DL4_01199 1080014 1080238 - Spore germination protein GerE Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature spore (CotB%2C CotC%2C CotG%2C CotS%2C CotV%2C CotW%2C CotX%2C CotY and CotZ). Controls also the cgeAB and cgeCDE operons. Contains 1 HTH luxR-type DNA-binding domain gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01199 BL14DL4_01200 BL14DL4_01200 BL14DL4_01200 1080414 1081112 - putative oxidoreductase Belongs to the short-chain dehydrogenases/reductases (SDR) family gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01200 BL14DL4_01201 BL14DL4_01201 BL14DL4_01201 1081130 1081600 - uncharacterized protein KEGG: bli:BL00319 acyl-CoA thioester hydrolase%3B Thiolester hydrolases gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01201 BL14DL4_01202 BL14DL4_01202 sdhB sdhB 1081663 1082427 - Succinate dehydrogenase (quinone) Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family%3B Contains 1 4Fe-4S ferredoxin-type domain%3B KEGG: bsu:BSU28430 succinate dehydrogenase / fumarate reductase%2C iron-sulfur subunit gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01202 BL14DL4_01203 BL14DL4_01203 sdhA sdhA 1082424 1084187 - Succinate dehydrogenase (quinone) Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily%3B KEGG: bsu:BSU28440 succinate dehydrogenase / fumarate reductase%2C flavoprotein subunit gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01203 BL14DL4_01204 BL14DL4_01204 BL14DL4_01204 1084221 1084829 - Succinate dehydrogenase cytochrome b558 subunit Di-heme cytochrome of the succinate dehydrogenase complex. Belongs to the cytochrome b558 family gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01204 BL14DL4_01205 BL14DL4_01205 BL14DL4_01205 1085131 1085574 + uncharacterized protein gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01205 BL14DL4_01206 BL14DL4_01206 lysC lysC 1085619 1086848 - Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: vsp:VS_2582 aspartate kinase gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01206 BL14DL4_01207 BL14DL4_01207 BL14DL4_01207 1087242 1089014 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision%3B Belongs to the UvrC family%3B Contains 1 GIY-YIG domain%3B Contains 1 UVR domain gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01207 BL14DL4_01208 BL14DL4_01208 BL14DL4_01208 1089157 1089471 - Thioredoxin Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01208 BL14DL4_01209 BL14DL4_01209 BL14DL4_01209 1089684 1090661 - Electron transfer flavoprotein subunit alpha The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF alpha-subunit/FixB family gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01209 BL14DL4_01210 BL14DL4_01210 BL14DL4_01210 1090711 1091484 - Electron transfer flavoprotein subunit beta The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)%3B Belongs to the ETF beta-subunit/FixA family gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01210 BL14DL4_01211 BL14DL4_01211 BL14DL4_01211 1091516 1092292 - Enoyl-CoA hydratase Involved in the degradation of long-chain fatty acids. Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: bsu:BSU28540 enoyl-CoA hydratase gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01211 BL14DL4_01212 BL14DL4_01212 BL14DL4_01212 1092295 1092897 - Fatty acid metabolism regulator protein Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01212 BL14DL4_01213 BL14DL4_01213 acsL acsL 1093034 1094713 - Long-chain-fatty-acid--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: care:LT85_4544 long-chain acyl-CoA synthetase gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01213 BL14DL4_01214 BL14DL4_01214 BL14DL4_01214 1094923 1095327 - UPF0719 transmembrane protein YshE Belongs to the UPF0719 family gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01214 BL14DL4_01215 BL14DL4_01215 BL14DL4_01215 1095346 1097703 - Endonuclease MutS2 Belongs to the DNA mismatch repair MutS family. MutS2 subfamily%3B Contains 1 Smr domain gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01215 BL14DL4_01216 BL14DL4_01216 BL14DL4_01216 1097720 1099435 - DNA polymerase/3'-5' exonuclease PolX Strictly DNA-template-directed DNA polymerase%2C preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a single-nucleotide gap%2C allowing further sealing of the resulting nick by a DNA ligase%2C points to a putative role in base excision repair (BER) during the B. subtilis life cycle. Moreover%2C also possesses a 3'-5' exonuclease activity able to edit unpaired 3'-termini in a gapped DNA substrate and likely involved in resecting unannealed 3'-termini during DNA repair. The same PolX molecule could perform the subsequent gap-filling step. Does not display 5'-deoxyribose 5'-phosphate (dRP) lyase activity%2C as predicted by the lack of the lysine and tyrosine residues responsible for the dRP lyase activity in some other PolX members%3B In the N-terminal sectio%3B belongs to the DNA polymerase type-X family%3B In the C-terminal sectio%3B belongs to the PHP family gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01216 BL14DL4_01217 BL14DL4_01217 BL14DL4_01217 1099579 1100115 - putative transmembrane protein YshB gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01217 BL14DL4_01218 BL14DL4_01218 BL14DL4_01218 1100124 1100381 - Cell division protein ZapA Activator of cell division through the inhibition of FtsZ GTPase activity%2C therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division%3B Belongs to the ZapA family. Type 2 subfamily gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01218 BL14DL4_01219 BL14DL4_01219 rnhC rnhC 1100531 1101472 + Ribonuclease H Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family. RnhC subfamily%3B KEGG: bsu:BSU28620 ribonuclease HIII gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01219 BL14DL4_01220 BL14DL4_01220 BL14DL4_01220 1102151 1103023 + hypothetical protein gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01220 BL14DL4_01221 BL14DL4_01221 BL14DL4_01221 1103473 1103772 + hypothetical protein gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01221 BL14DL4_01222 BL14DL4_01222 BL14DL4_01222 1103844 1105286 + hypothetical protein gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01222 BL14DL4_01223 BL14DL4_01223 phnC phnC 1105295 1105987 + Phosphonate-transporting ATPase ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: maq:Maqu_3258 phosphonate transport system ATP-binding protein gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01223 BL14DL4_01224 BL14DL4_01224 BL14DL4_01224 1105944 1106480 + hypothetical protein gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01224 BL14DL4_01225 BL14DL4_01225 BL14DL4_01225 1106491 1107039 + hypothetical protein gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01225 BL14DL4_01226 BL14DL4_01226 pheT pheT 1107211 1109625 - Phenylalanine--tRNA ligase Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily%3B Contains 1 B5 domain%3B Contains 1 FDX-ACB domain%3B Contains 1 tRNA-binding domain%3B KEGG: bsu:BSU28630 phenylalanyl-tRNA synthetase beta chain gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01226 BL14DL4_01227 BL14DL4_01227 pheS pheS 1109641 1110675 - Phenylalanine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily%3B KEGG: nmp:NMBB_0820 phenylalanyl-tRNA synthetase alpha chain gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01227 BL14DL4_01228 BL14DL4_01228 BL14DL4_01228 1111037 1111783 - putative tRNA/rRNA methyltransferase YsgA Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01228 BL14DL4_01229 BL14DL4_01229 BL14DL4_01229 1111898 1112113 + Small%2C acid-soluble spore protein Belongs to the SspI family gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01229 BL14DL4_01230 BL14DL4_01230 BL14DL4_01230 1112145 1113941 - Carbon starvation protein A like protein Belongs to the CstA family gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01230 BL14DL4_01231 BL14DL4_01231 BL14DL4_01231 1114145 1114420 - hypothetical protein gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01231 BL14DL4_01232 BL14DL4_01232 abfA abfA 1114514 1116022 - Non-reducing end alpha-L-arabinofuranosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in small oligosaccharides as alpha-(1->5)-linked arabinobiose/arabinotriose%2C but does not display significant activity against linear non-substituted arabinan. It is also highly efficient in the cleavage of alpha-(1->3)-linked arabinoside of xylobiose and of the alpha-(1->3)-linked arabinoside decorations of polymeric wheat arabinoxylan. It exhibits very low activity against sugar beet arabinan%3B Belongs to the glycosyl hydrolase 51 family%3B KEGG: bli:BL00345 alpha-N-arabinofuranosidase gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01232 BL14DL4_01233 BL14DL4_01233 BL14DL4_01233 1116058 1116900 - L-arabinose transport system permease protein AraQ Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01233 BL14DL4_01234 BL14DL4_01234 BL14DL4_01234 1116900 1117844 - L-arabinose transport system permease protein AraP Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01234 BL14DL4_01235 BL14DL4_01235 BL14DL4_01235 1117875 1119179 - putative arabinose-binding protein Part of the binding-protein-dependent transport system for L-arabinose. Belongs to the bacterial solute-binding protein 1 family gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01235 BL14DL4_01236 BL14DL4_01236 araM araM 1119183 1120382 - sn-glycerol-1-phosphate dehydrogenase Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bli:BL00349 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01236 BL14DL4_01237 BL14DL4_01237 BL14DL4_01237 1120399 1121085 - L-ribulose-5-phosphate 4-epimerase Belongs to the aldolase class II family. AraD/FucA subfamily%3B KEGG: sgl:SG1415 L-ribulose-5-phosphate 4-epimerase gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01237 BL14DL4_01238 BL14DL4_01238 BL14DL4_01238 1121101 1122759 - Ribulokinase Belongs to the ribulokinase family%3B KEGG: bsu:BSU28790 L-ribulokinase gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01238 BL14DL4_01239 BL14DL4_01239 BL14DL4_01239 1122807 1124288 - L-arabinose isomerase Catalyzes the conversion of L-arabinose to L-ribulose%3B Belongs to the arabinose isomerase family%3B KEGG: bli:BL00352 L-arabinose isomerase gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01239 BL14DL4_01240 BL14DL4_01240 BL14DL4_01240 1124553 1125515 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL00353 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01240 BL14DL4_01241 BL14DL4_01241 BL14DL4_01241 1125673 1126758 - Cellulase Putative aminopeptidase. Belongs to the peptidase M42 family%3B KEGG: bsu:BSU28820 endoglucanase gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01241 BL14DL4_01242 BL14DL4_01242 BL14DL4_01242 1126932 1127333 + Sigma-w pathway protein YsdB May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress. Might interact with and inhibit the activity of the protease PrsW%2C or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01242 BL14DL4_01243 BL14DL4_01243 BL14DL4_01243 1127350 1127592 - uncharacterized protein gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01243 BL14DL4_01244 BL14DL4_01244 BL14DL4_01244 1127730 1128089 - 50S ribosomal protein L20%2C chloroplastic Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit%3B Belongs to the ribosomal protein L20P family gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01244 BL14DL4_01245 BL14DL4_01245 BL14DL4_01245 1128123 1128323 - 50S ribosomal protein L35 Belongs to the ribosomal protein L35P family gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01245 BL14DL4_01246 BL14DL4_01246 BL14DL4_01246 1128341 1128976 - Translation initiation factor IF-3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits%2C thus enhancing the availability of 30S subunits on which protein synthesis initiation begins%3B Belongs to the IF-3 family gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01246 BL14DL4_01247 BL14DL4_01247 BL14DL4_01247 1129195 1129878 - Antiholin-like protein LrgB Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgA%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidB/LrgB family. LrgB subfamily gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01247 BL14DL4_01248 BL14DL4_01248 BL14DL4_01248 1129902 1130315 - Antiholin-like protein LrgA Inhibits the expression or activity of extracellular murein hydrolases by interacting%2C possibly with LrgB%2C with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD)%2C possibly triggering PCD in response to antibiotics and environmental stresses%3B Belongs to the CidA/LrgA family. LrgA subfamily gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01248 BL14DL4_01249 BL14DL4_01249 phoD phoD 1130552 1132108 + Alkaline phosphatase Belongs to the PhoD family%3B KEGG: bli:BL05301 alkaline phosphatase D gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01249 BL14DL4_01250 BL14DL4_01250 BL14DL4_01250 1132164 1132886 - Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01250 BL14DL4_01251 BL14DL4_01251 lytS lytS 1132861 1134645 - Histidine kinase Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. Contains 1 GAF domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00380 two-component system%2C LytT family%2C sensor histidine kinase LytS gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01251 BL14DL4_01252 BL14DL4_01252 BL14DL4_01252 1134805 1135032 - hypothetical protein gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01252 BL14DL4_01253 BL14DL4_01253 BL14DL4_01253 1135285 1136097 + Putative uncharacterized hydrolase YsaA Belongs to the HAD-like hydrolase superfamily gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01253 BL14DL4_01254 BL14DL4_01254 tarS tarS 1136129 1138060 - Threonine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: bli:BL00382 threonyl-tRNA synthetase gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01254 BL14DL4_01255 BL14DL4_01255 BL14DL4_01255 1138404 1139246 - uncharacterized protein gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01255 BL14DL4_01256 BL14DL4_01256 BL14DL4_01256 1139324 1139956 - TVP38/TMEM64 family membrane protein YtxB Belongs to the TVP38/TMEM64 family gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01256 BL14DL4_01257 BL14DL4_01257 BL14DL4_01257 1139995 1140930 - Primosomal protein DnaI gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01257 BL14DL4_01258 BL14DL4_01258 BL14DL4_01258 1140945 1142369 - Replication initiation and membrane attachment protein gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01258 BL14DL4_01259 BL14DL4_01259 BL14DL4_01259 1142486 1142944 - Transcriptional repressor NrdR Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes%3B Belongs to the NrdR family%3B Contains 1 ATP-cone domain gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01259 BL14DL4_01260 BL14DL4_01260 BL14DL4_01260 1142960 1143352 - hypothetical protein gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01260 BL14DL4_01261 BL14DL4_01261 speD speD 1143534 1143920 - Adenosylmethionine decarboxylase Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet)%2C the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine%3B Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily%3B KEGG: nis:NIS_1526 S-adenosylmethionine decarboxylase gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01261 BL14DL4_01262 BL14DL4_01262 gapA gapA 1144157 1145179 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01262 BL14DL4_01263 BL14DL4_01263 BL14DL4_01263 1145431 1146915 + Pectin lyase Belongs to the polysaccharide lyase 1 family%3B KEGG: bli:BL00361 pectin lyase gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01263 BL14DL4_01264 BL14DL4_01264 BL14DL4_01264 1146942 1147547 - Dephospho-CoA kinase Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B Belongs to the CoaE family%3B Contains 1 DPCK (dephospho-CoA kinase) domain%3B KEGG: ppr:PBPRA3204 dephospho-CoA kinase gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01264 BL14DL4_01265 BL14DL4_01265 BL14DL4_01265 1147565 1148197 - Putative membrane protein YtaF gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01265 BL14DL4_01266 BL14DL4_01266 mutM mutM 1148418 1149245 - DNA-formamidopyrimidine glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines%2C such as 7%2C8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates%3B Belongs to the FPG family%3B Contains 1 FPG-type zinc finger%3B KEGG: dma:DMR_16970 formamidopyrimidine-DNA glycosylase gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01266 BL14DL4_01267 BL14DL4_01267 BL14DL4_01267 1149264 1151903 - DNA-directed DNA polymerase In addition to polymerase activity%2C this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity%3B Belongs to the DNA polymerase type-A family%3B Contains 1 3'-5' exonuclease domain%3B Contains 1 5'-3' exonuclease domain%3B KEGG: bsu:BSU29090 DNA polymerase I gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01267 BL14DL4_01268 BL14DL4_01268 phoR phoR 1152159 1153904 - Histidine kinase Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU29100 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01268 BL14DL4_01269 BL14DL4_01269 BL14DL4_01269 1153897 1154619 - Phosphate regulon transcriptional regulatory protein This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01269 BL14DL4_01270 BL14DL4_01270 BL14DL4_01270 1154961 1155899 - Malate dehydrogenase Catalyzes the reversible oxidation of malate to oxaloacetate%3B Belongs to the LDH/MDH superfamily. MDH type 3 family%3B KEGG: bli:BL00397 malate dehydrogenase gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01270 BL14DL4_01271 BL14DL4_01271 idh1 idh1 1155948 1157264 - Isocitrate dehydrogenase (NADP(+)) Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: bld:BLi03061 isocitrate dehydrogenase gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01271 BL14DL4_01272 BL14DL4_01272 gltA gltA 1157387 1158505 - Citrate (Si)-synthase Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bsu:BSU29140 citrate synthase gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01272 BL14DL4_01273 BL14DL4_01273 BL14DL4_01273 1158928 1159392 - UPF0756 membrane protein Belongs to the UPF0756 family gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01273 BL14DL4_01274 BL14DL4_01274 BL14DL4_01274 1159494 1160609 + UPF0118 membrane protein YtvI Belongs to the UPF0118 (PerM) family gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01274 BL14DL4_01275 BL14DL4_01275 BL14DL4_01275 1160652 1161038 - UPF0716 protein YtzA Belongs to the UPF0716 (FxsA) family gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01275 BL14DL4_01276 BL14DL4_01276 BL14DL4_01276 1161351 1163108 - Pyruvate kinase Belongs to the pyruvate kinase family%3B KEGG: eco:b1676 pyruvate kinase gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01276 BL14DL4_01277 BL14DL4_01277 pfkA pfkA 1163133 1164092 - 6-phosphofructokinase Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1%2C6-bisphosphate by ATP%2C the first committing step of glycolysis%3B Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily%3B KEGG: eco:b3916 6-phosphofructokinase 1 gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01277 BL14DL4_01278 BL14DL4_01278 accA accA 1164335 1165312 - Acetyl-CoA carboxylase Component of the acetyl coenzyme A carboxylase (ACC) complex. First%2C biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA%3B Belongs to the AccA family%3B KEGG: bli:BL00404 acetyl-CoA carboxylase carboxyl transferase subunit alpha gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01278 BL14DL4_01279 BL14DL4_01279 accD accD 1165297 1166172 - Acetyl-CoA carboxylase Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA%3B Belongs to the AccD/PCCB family%3B KEGG: bli:BL00405 acetyl-CoA carboxylase carboxyl transferase subunit beta gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01279 BL14DL4_01280 BL14DL4_01280 sfcA sfcA 1166533 1167768 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU29220 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01280 BL14DL4_01281 BL14DL4_01281 BL14DL4_01281 1167911 1171255 - DNA-directed DNA polymerase DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)%3B Belongs to the DNA polymerase type-C family. DnaE subfamily%3B KEGG: bsu:BSU29230 DNA polymerase III subunit alpha gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01281 BL14DL4_01282 BL14DL4_01282 BL14DL4_01282 1171469 1171735 + Sporulation membrane protein YtrH Involved in sporulation. May contribute to cortex formation or stability gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01282 BL14DL4_01283 BL14DL4_01283 BL14DL4_01283 1171732 1172235 + Sporulation membrane protein YtrI Involved in sporulation gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01283 BL14DL4_01284 BL14DL4_01284 BL14DL4_01284 1172348 1172527 + uncharacterized protein gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01284 BL14DL4_01285 BL14DL4_01285 BL14DL4_01285 1172643 1173587 - Bifunctional oligoribonuclease and PAP phosphatase NrnA Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter%2C with a preference for 3-mers. Directionality is controversia%3B shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819)%2C and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP%3B Belongs to the NrnA oligoribonuclease family gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01285 BL14DL4_01286 BL14DL4_01286 BL14DL4_01286 1173734 1174036 + putative membrane protein YtpI gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01286 BL14DL4_01287 BL14DL4_01287 guaB guaB 1174065 1175396 - IMP dehydrogenase Contains 2 CBS domains%3B KEGG: afu:AF_1259 IMP dehydrogenase gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01287 BL14DL4_01288 BL14DL4_01288 BL14DL4_01288 1175480 1176037 - Negative transcription regulator PadR Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01288 BL14DL4_01289 BL14DL4_01289 BL14DL4_01289 1176154 1176840 - UPF0173 metal-dependent hydrolase Belongs to the UPF0173 family gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01289 BL14DL4_01290 BL14DL4_01290 BL14DL4_01290 1176875 1177684 - 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: blh:BaLi_c31620 3-oxoacyl-(acyl-carrier protein) reductase gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01290 BL14DL4_01291 BL14DL4_01291 BL14DL4_01291 1177815 1177958 - hypothetical protein gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01291 BL14DL4_01292 BL14DL4_01292 argH argH 1178033 1179412 - Argininosuccinate lyase Belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B KEGG: bam:Bamb_6457 argininosuccinate lyase gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01292 BL14DL4_01293 BL14DL4_01293 argG argG 1179409 1180620 - Argininosuccinate synthase Belongs to the argininosuccinate synthase family. Type 1 subfamily%3B KEGG: bli:BL00417 argininosuccinate synthase gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01293 BL14DL4_01294 BL14DL4_01294 BL14DL4_01294 1180813 1181331 - Molybdenum cofactor biosynthesis protein May be involved in the biosynthesis of molybdopterin%3B Belongs to the MoaB/Mog family gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01294 BL14DL4_01295 BL14DL4_01295 ackA ackA 1181430 1182617 - Acetate kinase Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction%3B Belongs to the acetokinase family%3B KEGG: tau:Tola_1703 acetate kinase gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01295 BL14DL4_01296 BL14DL4_01296 BL14DL4_01296 1182847 1183833 - Site-specific DNA-methyltransferase (adenine-specific) To type I restriction system adenine methylases%3B KEGG: bli:BL00420 site-specific DNA-methyltransferase (adenine-specific) gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01296 BL14DL4_01297 BL14DL4_01297 BL14DL4_01297 1183919 1184422 - Peroxiredoxin Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)%3B Belongs to the AhpC/TSA family. Tpx subfamily%3B Contains 1 thioredoxin domain%3B KEGG: pbc:CD58_15555 thiol peroxidase%2C atypical 2-Cys peroxiredoxin gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01297 BL14DL4_01298 BL14DL4_01298 BL14DL4_01298 1184568 1185026 - putative spore protein YtfJ gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01298 BL14DL4_01299 BL14DL4_01299 BL14DL4_01299 1185039 1185722 - uncharacterized protein gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01299 BL14DL4_01300 BL14DL4_01300 BL14DL4_01300 1185844 1186362 - putative membrane protein YteJ Contains 1 RDD domain gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01300 BL14DL4_01301 BL14DL4_01301 sppA sppA 1186378 1187385 - Putative signal peptide peptidase SppA Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-rich substrate peptides%3B Belongs to the peptidase S49 family%3B KEGG: bsu:BSU29530 protease IV%3B Serine endopeptidases gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01301 BL14DL4_01302 BL14DL4_01302 ppnK ppnK 1187578 1188375 + NAD(+) kinase Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bli:BL00367 NAD+ kinase gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01302 BL14DL4_01303 BL14DL4_01303 BL14DL4_01303 1188437 1189072 - Putative efflux system component YhbJ Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01303 BL14DL4_01304 BL14DL4_01304 BL14DL4_01304 1189431 1189434 - Uncharacterized MFS-type transporter YubD%3B nonfunctional due to frameshift pseudo gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01304 BL14DL4_01305 BL14DL4_01305 BL14DL4_01305 1190834 1191262 - putative HTH-type transcriptional regulator YxaD Contains 1 HTH marR-type DNA-binding domain gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01305 BL14DL4_01306 BL14DL4_01306 BL14DL4_01306 1191288 1192877 - Acetate--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29560 acetyl-CoA synthetase gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01306 BL14DL4_01307 BL14DL4_01307 BL14DL4_01307 1193020 1193232 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01307 BL14DL4_01308 BL14DL4_01308 BL14DL4_01308 1193344 1194549 - putative tRNA sulfurtransferase Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs%2C which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS%2C forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole%2C in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS%3B Belongs to the ThiI family%3B Contains 1 THUMP domain gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01308 BL14DL4_01309 BL14DL4_01309 BL14DL4_01309 1194557 1195702 - Cysteine desulfurase Catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily%3B KEGG: bsu:BSU29590 cysteine desulfurase gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01309 BL14DL4_01310 BL14DL4_01310 BL14DL4_01310 1195896 1197233 + Branched-chain amino acid transport system carrier protein BrnQ Component of the transport system for branched-chain amino acids (leucine%2C isoleucine and valine) Which is coupled to a proton motive force%3B Belongs to the branched chain amino acid transporter family gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01310 BL14DL4_01311 BL14DL4_01311 BL14DL4_01311 1197336 1199030 - Septation ring formation regulator EzrA Negative regulator of FtsZ ring formatio%3B modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization%3B Belongs to the EzrA family gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01311 BL14DL4_01312 BL14DL4_01312 BL14DL4_01312 1199219 1200031 + Histidinol-phosphatase Belongs to the PHP hydrolase family. HisK subfamily%3B KEGG: bsu:BSU29620 histidinol-phosphatase (PHP family) gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01312 BL14DL4_01313 BL14DL4_01313 BL14DL4_01313 1200024 1200662 - putative HTH-type transcriptional regulator YttP Contains 1 HTH tetR-type DNA-binding domain gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01313 BL14DL4_01314 BL14DL4_01314 BL14DL4_01314 1200791 1201285 + Protein YtsP Belongs to the free Met sulfoxide reductase family gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01314 BL14DL4_01315 BL14DL4_01315 BL14DL4_01315 1201299 1202999 - Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: yen:YE2425 diguanylate cyclase gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01315 BL14DL4_01316 BL14DL4_01316 BL14DL4_01316 1203329 1203931 + 30S ribosomal protein S4 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit%3B With S5 and S12 plays an important role in translational accuracy%3B Belongs to the ribosomal protein S4P family%3B Contains 1 S4 RNA-binding domain gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01316 BL14DL4_01317 BL14DL4_01317 BL14DL4_01317 1203967 1204155 - hypothetical protein gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01317 BL14DL4_01318 BL14DL4_01318 BL14DL4_01318 1204233 1204463 + hypothetical protein gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01318 BL14DL4_01319 BL14DL4_01319 BL14DL4_01319 1204753 1205190 - Inner membrane protein To E. coli YhaI gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01319 BL14DL4_01320 BL14DL4_01320 BL14DL4_01320 1205686 1206456 - UPF0173 protein YddR Belongs to the UPF0173 family gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01320 BL14DL4_01321 BL14DL4_01321 BL14DL4_01321 1206580 1206999 + Proline dehydrogenase transcriptional activator Transcriptional activator of the putA gene in response to proline. Contains 1 HTH asnC-type DNA-binding domain gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01321 BL14DL4_01322 BL14DL4_01322 BL14DL4_01322 1207050 1207196 - hypothetical protein gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01322 BL14DL4_01323 BL14DL4_01323 yarS yarS 1207329 1208594 - Tyrosine--tRNA ligase Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL00439 tyrosyl-tRNA synthetase gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01323 BL14DL4_01324 BL14DL4_01324 BL14DL4_01324 1208936 1210654 - Acetate--CoA ligase Catalyzes the conversion of acetate into acetyl-CoA (AcCoA)%2C an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction%2C AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction%2C it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA%2C forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bsu:BSU29680 acetyl-CoA synthetase gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01324 BL14DL4_01325 BL14DL4_01325 acuA acuA 1210810 1211442 + Acetoin utilization protein AcuA Part of the acuABC operon%2C which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bsu:BSU29690 acetoin utilization protein AcuA%3B Transferring groups other than amino-acyl groups gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01325 BL14DL4_01326 BL14DL4_01326 BL14DL4_01326 1211464 1212108 + Acetoin utilization protein AcuB Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Contains 2 CBS domains gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01326 BL14DL4_01327 BL14DL4_01327 BL14DL4_01327 1212105 1213265 + Acetoin utilization protein AcuC Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. Belongs to the histone deacetylase family gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01327 BL14DL4_01328 BL14DL4_01328 BL14DL4_01328 1213327 1214016 - putative 24.6 kDa protein in ccpA 3'region May be involved in some transport function. Belongs to the MotB family%3B Contains 1 OmpA-like domain gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01328 BL14DL4_01329 BL14DL4_01329 BL14DL4_01329 1214006 1214824 - uncharacterized protein May be involved in some transport function. Belongs to the MotA family gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01329 BL14DL4_01330 BL14DL4_01330 BL14DL4_01330 1214920 1215921 - Catabolite control protein Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions. Interacts with either P-Ser-HPr or P-Ser-Crh%2C leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01330 BL14DL4_01331 BL14DL4_01331 aroG aroG 1216237 1217313 - 3-deoxy-7-phosphoheptulonate synthase Belongs to the class-I DAHP synthase family%3B Contains 1 chorismate mutase domain%3B KEGG: bsu:BSU29750 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01331 BL14DL4_01332 BL14DL4_01332 BL14DL4_01332 1217424 1217582 - hypothetical protein gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01332 BL14DL4_01333 BL14DL4_01333 BL14DL4_01333 1217524 1217973 - UPF0134 protein Belongs to the UPF0134 family gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01333 BL14DL4_01334 BL14DL4_01334 BL14DL4_01334 1218123 1218449 - uncharacterized protein gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01334 BL14DL4_01335 BL14DL4_01335 BL14DL4_01335 1218470 1218886 - uncharacterized protein To C. plantagineum desiccation-related protein clone PCC3-06 gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01335 BL14DL4_01336 BL14DL4_01336 BL14DL4_01336 1218890 1219312 - UPF0478 protein YtxG Belongs to the UPF0478 family gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01336 BL14DL4_01337 BL14DL4_01337 murC murC 1219479 1220777 - UDP-N-acetylmuramate--L-alanine ligase Cell wall formation%3B Belongs to the MurCDEF family%3B KEGG: bsu:BSU29790 UDP-N-acetylmuramate--alanine ligase gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01337 BL14DL4_01338 BL14DL4_01338 BL14DL4_01338 1221043 1223721 - DNA translocase SftA Required for the accurate completion of chromosome partitioning%2C in part by promoting efficient resolution of chromosome dimers%2C before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cytokinesis%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01338 BL14DL4_01339 BL14DL4_01339 BL14DL4_01339 1223906 1224511 - Putative tRNA-binding protein YtpR Contains 1 tRNA-binding domain gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01339 BL14DL4_01340 BL14DL4_01340 BL14DL4_01340 1224530 1225339 - UPF0354 protein Belongs to the UPF0354 family gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01340 BL14DL4_01341 BL14DL4_01341 BL14DL4_01341 1225359 1225679 - Thioredoxin-like protein YtpP Contains 1 thioredoxin domain gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01341 BL14DL4_01342 BL14DL4_01342 BL14DL4_01342 1225969 1226415 + uncharacterized protein gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01342 BL14DL4_01343 BL14DL4_01343 pepA pepA 1226468 1227541 - Glutamyl aminopeptidase Belongs to the peptidase M42 family%3B KEGG: cml:BN424_1132 glutamyl aminopeptidase gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01343 BL14DL4_01344 BL14DL4_01344 BL14DL4_01344 1227678 1227992 + uncharacterized protein gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01344 BL14DL4_01345 BL14DL4_01345 BL14DL4_01345 1228029 1229726 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bli:BL00044 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01345 BL14DL4_01346 BL14DL4_01346 BL14DL4_01346 1229799 1230644 - putative quorum-quenching lactonase YtnP Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus. Thus%2C serves as a defensive strategy against competing bacteria. The putative target for YtnP may be a gamma-butyrolactone termed A factor%2C which is the quorum- sensing signaling molecule that positively regulates streptomycin production and development of aerial hyphae in S. griseus%3B Belongs to the metallo-beta-lactamase superfamily gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01346 BL14DL4_01347 BL14DL4_01347 trmB trmB 1230740 1231381 - tRNA (guanine(46)-N(7))-methyltransferase Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family%3B KEGG: bsu:BSU29900 tRNA (guanine-N7-)-methyltransferase gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01347 BL14DL4_01348 BL14DL4_01348 BL14DL4_01348 1231562 1231840 + uncharacterized protein gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01348 BL14DL4_01349 BL14DL4_01349 BL14DL4_01349 1231835 1232638 - Putative phosphotransferase YtmP Belongs to the aminoglycoside phosphotransferase family gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01349 BL14DL4_01350 BL14DL4_01350 BL14DL4_01350 1232827 1234959 - Pullulanase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL00040 pullulanase gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01350 BL14DL4_01351 BL14DL4_01351 cerK cerK 1234986 1235906 - Ceramide kinase May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact%2C is not able to exhibit diacylglycerol kinase activity in vitro. Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: ppp:PHYPADRAFT_158844 ceramide kinase gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01351 BL14DL4_01352 BL14DL4_01352 BL14DL4_01352 1235959 1236900 - uncharacterized protein gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01352 BL14DL4_01353 BL14DL4_01353 ligT ligT 1236884 1237489 - RNA 2'%2C3'-cyclic phosphodiesterase Hydrolyzes RNA 2'%2C3'-cyclic phosphodiester to an RNA 2'- phosphomonoester%3B Belongs to the 2H phosphoesterase superfamily. ThpR family%3B KEGG: bli:BL00037 2'-5' RNA ligase%3B Forming phosphoric ester bonds gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01353 BL14DL4_01354 BL14DL4_01354 cysK cysK 1237627 1238559 + Cysteine synthase Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bli:BL00070 cysteine synthase A gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01354 BL14DL4_01355 BL14DL4_01355 BL14DL4_01355 1239362 1239364 + Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01355 BL14DL4_01356 BL14DL4_01356 dapE dapE 1239518 1240909 - Succinyl-diaminopimelate desuccinylase Belongs to the peptidase M20A family%3B KEGG: bli:BL00035 succinyl-diaminopimelate desuccinylase gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01356 BL14DL4_01357 BL14DL4_01357 BL14DL4_01357 1241017 1242324 + Guanine/hypoxanthine permease PbuO Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM%3B Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01357 BL14DL4_01358 BL14DL4_01358 BL14DL4_01358 1242657 1242878 + putative HTH-type transcriptional regulator YtzE Contains 1 HTH deoR-type DNA-binding domain gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01358 BL14DL4_01359 BL14DL4_01359 rsuA rsuA 1242999 1243721 - 16S rRNA pseudouridine(516) synthase Belongs to the pseudouridine synthase RsuA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: par:Psyc_0024 16S rRNA pseudouridine516 synthase__ gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01359 BL14DL4_01360 BL14DL4_01360 BL14DL4_01360 1243761 1245404 - putative cell division protein YtgP May play a role in cell division%2C although it is not essential for growth%3B Belongs to the polysaccharide synthase family gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01360 BL14DL4_01361 BL14DL4_01361 BL14DL4_01361 1245624 1246898 + uncharacterized protein gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01361 BL14DL4_01362 BL14DL4_01362 BL14DL4_01362 1247126 1248664 + Glycine betaine transporter OpuD High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake%3B Belongs to the BCCT transporter (TC 2. A. 15) family gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01362 BL14DL4_01363 BL14DL4_01363 BL14DL4_01363 1248700 1248882 - Sporulation protein cse60 gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01363 BL14DL4_01364 BL14DL4_01364 BL14DL4_01364 1249058 1249375 - UPF0033 protein YrkF Belongs to the UPF0033 family%3B Contains 1 rhodanese domain gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01364 BL14DL4_01365 BL14DL4_01365 BL14DL4_01365 1249455 1249589 - hypothetical protein gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01365 BL14DL4_01366 BL14DL4_01366 rapI rapI 1249586 1250599 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bha:BH1987 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01366 BL14DL4_01367 BL14DL4_01367 BL14DL4_01367 1250799 1251158 - hypothetical protein gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01367 BL14DL4_01368 BL14DL4_01368 BL14DL4_01368 1251195 1251842 - uncharacterized protein gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01368 BL14DL4_01369 BL14DL4_01369 iolG iolG 1251859 1253136 - Inositol 2-dehydrogenase May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: rhi:NGR_b04530 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase__ gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01369 BL14DL4_01370 BL14DL4_01370 BL14DL4_01370 1253156 1253650 - Putative lipoprotein YteS May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01370 BL14DL4_01371 BL14DL4_01371 yteR yteR 1253647 1254768 - Unsaturated rhamnogalacturonyl hydrolase Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D- galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D- glucuronic acid at the non-reducing terminus%2C although the active pockets of YesR and UGL are very similar%3B Belongs to the glycosyl hydrolase 105 family%3B KEGG: bli:BL00024 unsaturated rhamnogalacturonyl hydrolase gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01371 BL14DL4_01372 BL14DL4_01372 BL14DL4_01372 1254797 1255762 - putative multiple-sugar transport system permease YteP Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01372 BL14DL4_01373 BL14DL4_01373 yesM yesM 1255978 1258287 + Histidine kinase Contains 1 HTH araC/xylS-type DNA-binding domain%3B KEGG: pod:PODO_24995 two-component system%2C sensor histidine kinase YesM__ gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01373 BL14DL4_01374 BL14DL4_01374 BL14DL4_01374 1258521 1260026 - Putative ABC transporter peptide-binding protein YtcQ Probably part of a binding-protein-dependent transport system%3B Belongs to the bacterial solute-binding protein 1 family gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01374 BL14DL4_01375 BL14DL4_01375 BL14DL4_01375 1260043 1260891 - putative ABC transporter permease protein YtcP Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01375 BL14DL4_01376 BL14DL4_01376 BL14DL4_01376 1261062 1261826 - uncharacterized protein Belongs to the NAD(P)-dependent epimerase/dehydratase family gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01376 BL14DL4_01377 BL14DL4_01377 BL14DL4_01377 1261844 1262731 - Putative hydrolase Belongs to the dienelactone hydrolase family gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01377 BL14DL4_01378 BL14DL4_01378 BL14DL4_01378 1262763 1264013 - putative amino acid permease YecA Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01378 BL14DL4_01379 BL14DL4_01379 BL14DL4_01379 1264142 1265035 + putative HTH-type transcriptional regulator YwqM Contains 1 HTH lysR-type DNA-binding domain gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01379 BL14DL4_01380 BL14DL4_01380 preP preP 1265041 1265445 - Prolyl oligopeptidase KEGG: vfi:VF_A0660 prolyl oligopeptidase__ gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01380 BL14DL4_01381 BL14DL4_01381 larS larS 1265576 1267990 - Leucine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: dvu:DVU1196 leucyl-tRNA synthetase gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01381 BL14DL4_01382 BL14DL4_01382 BL14DL4_01382 1268412 1268741 - uncharacterized protein gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01382 BL14DL4_01383 BL14DL4_01383 BL14DL4_01383 1268962 1270143 - putative MFS-type transporter YttB Belongs to the major facilitator superfamily gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01383 BL14DL4_01384 BL14DL4_01384 BL14DL4_01384 1270263 1271087 - putative D-methionine-binding lipoprotein MetQ This protein is a component of a D-methionine permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the NlpA lipoprotein family gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01384 BL14DL4_01385 BL14DL4_01385 BL14DL4_01385 1271383 1272063 + putative membrane protein YttA gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01385 BL14DL4_01386 BL14DL4_01386 BL14DL4_01386 1272091 1273383 - ABC transporter permease YtrF Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-4 integral membrane protein family gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01386 BL14DL4_01387 BL14DL4_01387 BL14DL4_01387 1273412 1274110 - ABC transporter ATP-binding protein YtrE Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01387 BL14DL4_01388 BL14DL4_01388 BL14DL4_01388 1274136 1275113 - putative ABC transporter permease YtrC Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Belongs to the ABC-5 integral membrane protein family gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01388 BL14DL4_01389 BL14DL4_01389 BL14DL4_01389 1275107 1275985 - L-arabinose transport ATP-binding protein AraG Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01389 BL14DL4_01390 BL14DL4_01390 BL14DL4_01390 1275978 1276370 - HTH-type transcriptional repressor YtrA Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01390 BL14DL4_01391 BL14DL4_01391 BL14DL4_01391 1276413 1276541 - hypothetical protein gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01391 BL14DL4_01392 BL14DL4_01392 BL14DL4_01392 1276667 1276939 - uncharacterized protein gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01392 BL14DL4_01393 BL14DL4_01393 BL14DL4_01393 1277092 1278060 + Putative protein YtqA Belongs to the radical SAM superfamily gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01393 BL14DL4_01394 BL14DL4_01394 BL14DL4_01394 1278057 1278641 + Putative rRNA methylase YtqB Belongs to the methyltransferase superfamily gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01394 BL14DL4_01395 BL14DL4_01395 BL14DL4_01395 1278822 1280072 + Proton glutamate symport protein This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01395 BL14DL4_01396 BL14DL4_01396 ytpB ytpB 1280113 1281192 - Tetraprenyl-beta-curcumene synthase Catalyzes the transformation of a linear C35 prenyl diphosphate chain to form tetraprenyl-beta-curcumene%3B KEGG: bsu:BSU30500 tetraprenyl-beta-curcumene synthase gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01396 BL14DL4_01397 BL14DL4_01397 pldB pldB 1281207 1281986 - Lysophospholipase Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis reaction of one acyl bond in phosphatidylcholine in vitro (actual cleavage point is unknown)%2C resulting in lysophosphatidylcholine%3B Belongs to the AB hydrolase superfamily%3B KEGG: bli:BL00003 lysophospholipase gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01397 BL14DL4_01398 BL14DL4_01398 BL14DL4_01398 1282030 1282548 + putative transferase YtoA Belongs to the transferase hexapeptide repeat family gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01398 BL14DL4_01399 BL14DL4_01399 BL14DL4_01399 1282725 1283249 + Undecaprenyl-diphosphate phosphatase KEGG: bli:BL00058 undecaprenyl-diphosphatase gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01399 BL14DL4_01400 BL14DL4_01400 BL14DL4_01400 1283308 1284444 + GDP-mannose-dependent alpha-mannosyltransferase Catalyzes the addition of a mannose residue from GDP-D- mannose to GlcAGroAc2 to generate 1%2C2-di-O-C16/C18:1-(alpha-D- mannopyranosyl)-(1-4)-(alpha-D-glucopyranosyluronic acid)-(1-3)- glycerol(ManGlcAGroAc2)%3B Belongs to the glycosyltransferase group 1 family%3B KEGG: bcz:BCZK4513 null%3B Hexosyltransferases gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01400 BL14DL4_01401 BL14DL4_01401 asnB asnB 1284488 1286386 - Asparagine synthase (glutamine-hydrolyzing) Main asparagine synthetase in vegetative cells. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU30540 asparagine synthase (glutamine-hydrolysing) gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01401 BL14DL4_01402 BL14DL4_01402 metK metK 1286616 1287818 - Methionine adenosyltransferase Catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B Belongs to the AdoMet synthase family%3B KEGG: geo:Geob_1656 S-adenosylmethionine synthetase__ gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01402 BL14DL4_01403 BL14DL4_01403 pckA pckA 1288542 1290125 + Phosphoenolpyruvate carboxykinase (ATP) Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA%3B Belongs to the phosphoenolpyruvate carboxykinase [ATP] family%3B KEGG: bli:BL00839 phosphoenolpyruvate carboxykinase (ATP) gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01403 BL14DL4_01404 BL14DL4_01404 BL14DL4_01404 1290375 1291559 + hypothetical protein gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01404 BL14DL4_01405 BL14DL4_01405 BL14DL4_01405 1291600 1291842 - uncharacterized protein gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01405 BL14DL4_01406 BL14DL4_01406 dpp4 dpp4 1291867 1292667 - Dipeptidyl-peptidase IV Belongs to the peptidase S9B family%3B KEGG: ehx:EMIHUDRAFT_466891 dipeptidyl-peptidase 4__ gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01406 BL14DL4_01407 BL14DL4_01407 BL14DL4_01407 1292775 1293767 + Putative binding protein YtlA Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01407 BL14DL4_01408 BL14DL4_01408 BL14DL4_01408 1293780 1294568 + Lipoprotein-releasing system ATP-binding protein LolD Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01408 BL14DL4_01409 BL14DL4_01409 BL14DL4_01409 1294531 1295355 + putative ABC transporter permease protein YtlD Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01409 BL14DL4_01410 BL14DL4_01410 BL14DL4_01410 1295386 1295862 - 8-oxo-dGTP diphosphatase Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Functions%2C in conjuction with MutT%2C to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores. According to PubMed:15576788%2C phosphohydrolase that catalyzes the hydrolysis of all common nucleoside triphosphates as well as of the mutagenic analog 8-oxo- dGTP. The high catalytic efficiency on dGTP is in contrast to results from PubMed:14761999. According to PubMed:14761999%2C catalyzes the hydrolysis of 8-oxo-dGTP with a specific activity 413 times higher than that exhibited against dGTP. Preferentially catalyzes the hydrolysis of 8-oxo-dGTP and 8-oxo-GTP. According to PubMed:15576788%2C hydrolyzes nucleoside triphosphates in a stepwise fashion through the diphosphate to the monophosphate%2C releasing two molecules of inorganic orthophosphate%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU30630 8-oxo-dGTP diphosphatase gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01410 BL14DL4_01411 BL14DL4_01411 BL14DL4_01411 1296057 1296380 - hypothetical protein gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01411 BL14DL4_01412 BL14DL4_01412 BL14DL4_01412 1296428 1296832 - uncharacterized protein Belongs to the Cp-1 holin family gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01412 BL14DL4_01413 BL14DL4_01413 BL14DL4_01413 1296984 1297421 - DNA protection during starvation protein Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions%2C which prevents hydroxyl radical production by the Fenton Fe(2+) ion (By similarity). It is capable of binding and sequestering Fe(2+) ion. Does not bind DNA%3B Belongs to the Dps family gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01413 BL14DL4_01414 BL14DL4_01414 BL14DL4_01414 1297555 1297698 + hypothetical protein gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01414 BL14DL4_01415 BL14DL4_01415 BL14DL4_01415 1297692 1298135 - uncharacterized protein gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01415 BL14DL4_01416 BL14DL4_01416 luxS luxS 1298267 1298740 - S-ribosylhomocysteine lyase Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4%2C5- dihydroxy-2%2C3-pentadione (DPD)%3B Belongs to the LuxS family%3B KEGG: bsu:BSU30670 S-ribosylhomocysteine lyase gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01416 BL14DL4_01417 BL14DL4_01417 BL14DL4_01417 1298878 1299105 + Putative membrane protein insertion efficiency factor Could be involved in insertion of integral membrane proteins into the membrane%3B Belongs to the UPF0161 family gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01417 BL14DL4_01418 BL14DL4_01418 cynT cynT 1299102 1299671 - Carbonate dehydratase Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: salv:SALWKB2_2139 carbonic anhydrase__ gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01418 BL14DL4_01419 BL14DL4_01419 BL14DL4_01419 1299798 1300979 + COBW domain-containing protein Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01419 BL14DL4_01420 BL14DL4_01420 BL14DL4_01420 1301078 1302118 + Zinc-binding protein AdcA Part of the ATP-driven transport system AdcABC for zinc. Belongs to the bacterial solute-binding protein 9 family gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01420 BL14DL4_01421 BL14DL4_01421 BL14DL4_01421 1302204 1302449 - 50S ribosomal protein L31 type Belongs to the ribosomal protein L31P family. Type B subfamily gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01421 BL14DL4_01422 BL14DL4_01422 cydA cydA 1302641 1303966 + Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor__ gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01422 BL14DL4_01423 BL14DL4_01423 cydB cydB 1303996 1305048 + Putative cytochrome bd menaquinol oxidase subunit II May have a role in sporulation. Can compensate for the loss of cytochrome aa3%3B Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bld:BLi03216 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01423 BL14DL4_01424 BL14DL4_01424 BL14DL4_01424 1305093 1305254 + uncharacterized protein gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01424 BL14DL4_01425 BL14DL4_01425 BL14DL4_01425 1305281 1305472 + hypothetical protein gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01425 BL14DL4_01426 BL14DL4_01426 menC menC 1305631 1306740 - o-succinylbenzoate synthase Converts 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily%3B KEGG: bli:BL02404 O-succinylbenzoate synthase gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01426 BL14DL4_01427 BL14DL4_01427 menE menE 1306753 1308189 - o-succinylbenzoate--CoA ligase Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA)%3B Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily%3B KEGG: bli:BL02405 O-succinylbenzoic acid--CoA ligase gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01427 BL14DL4_01428 BL14DL4_01428 menB menB 1308267 1309085 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1%2C4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)%3B Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily%3B KEGG: bst:GYO_3334 naphthoate synthase__ gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01428 BL14DL4_01429 BL14DL4_01429 menH menH 1309099 1309911 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase Catalyzes a proton abstraction reaction that results in 2%2C5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate (SHCHC)%3B Belongs to the AB hydrolase superfamily. MenH family%3B KEGG: bsu:BSU30810 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01429 BL14DL4_01430 BL14DL4_01430 menD menD 1309908 1311650 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acidsynthase Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)%3B Belongs to the TPP enzyme family. MenD subfamily%3B KEGG: bli:BL02408 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01430 BL14DL4_01431 BL14DL4_01431 menF menF 1311647 1313071 - Isochorismate synthase Catalyzes the conversion of chorismate to isochorismate%3B Belongs to the isochorismate synthase family%3B KEGG: bsu:BSU30830 menaquinone-specific isochorismate synthase gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01431 BL14DL4_01432 BL14DL4_01432 menA menA 1313340 1314272 + 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase Conversion of 1%2C4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK)%3B Belongs to the MenA family. Type 1 subfamily%3B KEGG: bli:BL01413 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase%3B 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01432 BL14DL4_01433 BL14DL4_01433 BL14DL4_01433 1314381 1315136 + uncharacterized protein Contains 1 dksA C4-type zinc finger gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01433 BL14DL4_01434 BL14DL4_01434 glgP glgP 1315170 1317569 - Glycogen phosphorylase Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However%2C all known phosphorylases share catalytic and structural properties. Belongs to the glycogen phosphorylase family%3B KEGG: bli:BL01415 starch phosphorylase gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01434 BL14DL4_01435 BL14DL4_01435 glgA glgA 1317556 1319010 - Starch synthase Synthesizes alpha-1%2C4-glucan chains using ADP-glucose%3B Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily%3B KEGG: pat:Patl_0080 starch synthase__ gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01435 BL14DL4_01436 BL14DL4_01436 BL14DL4_01436 1319007 1320035 - Glucose-1-phosphate adenylyltransferase Catalyzes the synthesis of ADP-glucose%2C a sugar donor used in elongation reactions on alpha-glucans%3B Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family%3B KEGG: bli:BL01417 glucose-1-phosphate adenylyltransferase gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01436 BL14DL4_01437 BL14DL4_01437 BL14DL4_01437 1320062 1321201 - Glucose-1-phosphate adenylyltransferase Catalyzes the synthesis of ADP-glucose%2C a sugar donor used in elongation reactions on alpha-glucans%3B Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family%3B KEGG: bli:BL01418 glucose-1-phosphate adenylyltransferase gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01437 BL14DL4_01438 BL14DL4_01438 glgB glgB 1321198 1323081 - 1%2C4-alpha-glucan branching enzyme Catalyzes the formation of the alpha-1%2C6-glucosidic linkages in glycogen by scission of a 1%2C4-alpha-linked oligosaccharide from growing alpha-1%2C4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1%2C6 position%3B Belongs to the glycosyl hydrolase 13 family. GlgB subfamily%3B KEGG: bli:BL01419 1%2C4-alpha-glucan branching enzyme gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01438 BL14DL4_01439 BL14DL4_01439 BL14DL4_01439 1323265 1323339 - tRNA-Glu tRNA gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01439 BL14DL4_01440 BL14DL4_01440 BL14DL4_01440 1323352 1323442 - tRNA-Ser tRNA gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01440 BL14DL4_01441 BL14DL4_01441 BL14DL4_01441 1323444 1323518 - tRNA-Asn tRNA gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01441 BL14DL4_01442 BL14DL4_01442 BL14DL4_01442 1323525 1323601 - tRNA-Ile tRNA gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01442 BL14DL4_01443 BL14DL4_01443 BL14DL4_01443 1323614 1323687 - tRNA-Gly tRNA gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01443 BL14DL4_01444 BL14DL4_01444 BL14DL4_01444 1323696 1323771 - tRNA-His tRNA gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01444 BL14DL4_01445 BL14DL4_01445 BL14DL4_01445 1323794 1323869 - tRNA-Phe tRNA gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01445 BL14DL4_01446 BL14DL4_01446 BL14DL4_01446 1323880 1323956 - tRNA-Asp tRNA gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01446 BL14DL4_01447 BL14DL4_01447 BL14DL4_01447 1324002 1324078 - tRNA-Met tRNA gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01447 BL14DL4_01448 BL14DL4_01448 BL14DL4_01448 1324103 1324195 - tRNA-Ser tRNA gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01448 BL14DL4_01449 BL14DL4_01449 BL14DL4_01449 1324203 1324279 - tRNA-Met tRNA gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01449 BL14DL4_01450 BL14DL4_01450 BL14DL4_01450 1324285 1324358 - tRNA-Met tRNA gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01450 BL14DL4_01451 BL14DL4_01451 BL14DL4_01451 1324384 1324456 - tRNA-Ala tRNA gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01451 BL14DL4_01452 BL14DL4_01452 BL14DL4_01452 1324463 1324539 - tRNA-Pro tRNA gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01452 BL14DL4_01453 BL14DL4_01453 BL14DL4_01453 1324548 1324624 - tRNA-Arg tRNA gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01453 BL14DL4_01454 BL14DL4_01454 BL14DL4_01454 1324635 1324706 - tRNA-Gly tRNA gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01454 BL14DL4_01455 BL14DL4_01455 BL14DL4_01455 1324722 1324806 - tRNA-Leu tRNA gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01455 BL14DL4_01456 BL14DL4_01456 BL14DL4_01456 1324813 1324888 - tRNA-Lys tRNA gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01456 BL14DL4_01457 BL14DL4_01457 BL14DL4_01457 1324970 1325045 - tRNA-Thr tRNA gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01457 BL14DL4_01458 BL14DL4_01458 BL14DL4_01458 1325061 1325136 - tRNA-Val tRNA gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01458 BL14DL4_01459 BL14DL4_01459 BL14DL4_01459 1325332 1325538 - hypothetical protein gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01459 BL14DL4_01460 BL14DL4_01460 BL14DL4_01460 1325863 1325978 - 5S ribosomal RNA rRNA gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01460 BL14DL4_01461 BL14DL4_01461 BL14DL4_01461 1326110 1329040 - 23S ribosomal RNA rRNA gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01461 BL14DL4_01462 BL14DL4_01462 BL14DL4_01462 1329215 1330764 - 16S ribosomal RNA rRNA gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01462 BL14DL4_01463 BL14DL4_01463 BL14DL4_01463 1331391 1332491 - Arabinose metabolism transcriptional repressor Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene%2C and to one sequence in the araR promoter. Contains 1 HTH gntR-type DNA-binding domain gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01463 BL14DL4_01464 BL14DL4_01464 BL14DL4_01464 1332865 1333449 + Thiamine transporter ThiT Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane%2C not extracytoplasmic soluble proteins (By similarity)%3B Belongs to the ECF family. Thiamine transporter (TC 2. A. 88) subfamily gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01464 BL14DL4_01465 BL14DL4_01465 srtA srtA 1333490 1334047 - Sortase A KEGG: blh:BaLi_c33300 sortase A__ gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01465 BL14DL4_01466 BL14DL4_01466 BL14DL4_01466 1334154 1335149 - hypothetical protein gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01466 BL14DL4_01467 BL14DL4_01467 BL14DL4_01467 1335330 1335518 + hypothetical protein gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01467 BL14DL4_01468 BL14DL4_01468 rapD rapD 1335644 1336756 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02513 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01468 BL14DL4_01469 BL14DL4_01469 BL14DL4_01469 1336758 1336886 + hypothetical protein gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01469 BL14DL4_01470 BL14DL4_01470 BL14DL4_01470 1336966 1337613 + Pyroglutamyl-peptidase I Removes 5-oxoproline from various penultimate amino acid residues except L-proline. Belongs to the peptidase C15 family%3B KEGG: bsu:BSU02650 pyroglutamyl-peptidase gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01470 BL14DL4_01471 BL14DL4_01471 BL14DL4_01471 1337732 1338388 + Ktr system potassium uptake protein Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01471 BL14DL4_01472 BL14DL4_01472 BL14DL4_01472 1338391 1339710 + Ktr system potassium uptake protein Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01472 BL14DL4_01473 BL14DL4_01473 BL14DL4_01473 1339721 1340635 - putative transporter Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01473 BL14DL4_01474 BL14DL4_01474 BL14DL4_01474 1340760 1341242 + uncharacterized protein gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01474 BL14DL4_01475 BL14DL4_01475 BL14DL4_01475 1341289 1341870 - Putative metal-sulfur cluster biosynthesis protein YuaD Contains 1 MOSC domain gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01475 BL14DL4_01476 BL14DL4_01476 gbsB gbsB 1341982 1343190 - Alcohol dehydrogenase Essential for the utilization of choline as a precursor%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31050 choline dehydrogenase gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01476 BL14DL4_01477 BL14DL4_01477 betB betB 1343208 1344680 - Betaine-aldehyde dehydrogenase This is a soluble NAD-dependent betaine aldehyde- specific dehydrogenase. Essential for the utilization of choline as a precursor%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bsu:BSU31060 betaine-aldehyde dehydrogenase gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01477 BL14DL4_01478 BL14DL4_01478 BL14DL4_01478 1345004 1345558 + HTH-type transcriptional repressor GbsR Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved%3B Belongs to the GbsR family gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01478 BL14DL4_01479 BL14DL4_01479 BL14DL4_01479 1345678 1347306 + High-affinity choline transporter Imports choline from the extracellular space to the neuron with high affinity. Rate-limiting step in acetylcholine synthesis. Sodium ion and chloride ion dependent (By similarity)%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01479 BL14DL4_01480 BL14DL4_01480 BL14DL4_01480 1347350 1348267 - Putative S-adenosyl-L-methionine-dependent methyltransferase YktD May be involved in polyketide synthesis. Belongs to the UPF0677 family gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01480 BL14DL4_01481 BL14DL4_01481 BL14DL4_01481 1348442 1349623 - Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bsu:BSU17640 alanine racemase gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01481 BL14DL4_01482 BL14DL4_01482 oxdD oxdD 1349938 1351119 + Oxalate decarboxylase Converts oxalate to formate and CO(2). To B. subtilis OxdC%3B KEGG: bsm:BSM4216_3794 oxalate decarboxylase__ gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01482 BL14DL4_01483 BL14DL4_01483 BL14DL4_01483 1351667 1352188 + hypothetical protein gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01483 BL14DL4_01484 BL14DL4_01484 BL14DL4_01484 1352196 1353155 + hypothetical protein gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01484 BL14DL4_01485 BL14DL4_01485 BL14DL4_01485 1353576 1354250 - N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01485 BL14DL4_01486 BL14DL4_01486 BL14DL4_01486 1354377 1354559 + hypothetical protein gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01486 BL14DL4_01487 BL14DL4_01487 BL14DL4_01487 1354619 1354691 - tRNA-Ala tRNA gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01487 BL14DL4_01488 BL14DL4_01488 thiE thiE 1354806 1355792 - Thiamine phosphate synthase Belongs to the ADP-ribosylglycohydrolase family%3B KEGG: mst:Msp_0683 thiamine-phosphate pyrophosphorylase__ gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01488 BL14DL4_01489 BL14DL4_01489 BL14DL4_01489 1356019 1356654 - hypothetical protein gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01489 BL14DL4_01490 BL14DL4_01490 BL14DL4_01490 1356671 1358344 - hypothetical protein gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01490 BL14DL4_01491 BL14DL4_01491 BL14DL4_01491 1358364 1358687 - hypothetical protein gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01491 BL14DL4_01492 BL14DL4_01492 BL14DL4_01492 1358684 1359391 - hypothetical protein gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01492 BL14DL4_01493 BL14DL4_01493 BL14DL4_01493 1359409 1359759 - hypothetical protein gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01493 BL14DL4_01494 BL14DL4_01494 BL14DL4_01494 1359778 1360137 - hypothetical protein gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01494 BL14DL4_01495 BL14DL4_01495 BL14DL4_01495 1360431 1360640 + uncharacterized protein gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01495 BL14DL4_01496 BL14DL4_01496 BL14DL4_01496 1360663 1360836 + hypothetical protein gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01496 BL14DL4_01497 BL14DL4_01497 BL14DL4_01497 1360857 1362338 - hypothetical protein gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01497 BL14DL4_01498 BL14DL4_01498 BL14DL4_01498 1362355 1363488 - 1%2C2-diacylglycerol 3-glucosyltransferase Belongs to the glycosyltransferase 28 family%3B KEGG: pjd:Pjdr2_5001 processive 1%2C2-diacylglycerol beta-glucosyltransferase__ gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01498 BL14DL4_01499 BL14DL4_01499 BL14DL4_01499 1363588 1364136 + uncharacterized protein gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01499 BL14DL4_01500 BL14DL4_01500 BL14DL4_01500 1364181 1364996 - putative metallophosphoesterase YkoQ Belongs to the metallophosphoesterase superfamily gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01500 BL14DL4_01501 BL14DL4_01501 bacA bacA 1365128 1365958 - Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: bli:BL02576 undecaprenyl-diphosphatase gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01501 BL14DL4_01502 BL14DL4_01502 BL14DL4_01502 1366036 1367181 - UPF0118 membrane protein YubA Belongs to the UPF0118 (PerM) family gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01502 BL14DL4_01503 BL14DL4_01503 BL14DL4_01503 1367396 1368379 + D-xylose 1-dehydrogenase (NADP(+)) NADP-dependent D-xylose dehydrogenase involved in the degradation of D-xylose%2C a major component of hemicelluloses such as xylan. Even if it shows D-xylose dehydrogenase activity%2C it is not essential for D-xylose degradation%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: lsa:LSA1535 null%3B Oxidoreductases gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01503 BL14DL4_01504 BL14DL4_01504 BL14DL4_01504 1368424 1368948 - uncharacterized protein Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: dsa:Desal_2750 protease I%3B Glycosylases__ gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01504 BL14DL4_01505 BL14DL4_01505 BL14DL4_01505 1369081 1371063 - Methyl-accepting chemotaxis protein McpB Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01505 BL14DL4_01506 BL14DL4_01506 BL14DL4_01506 1371197 1373182 - Methyl-accepting chemotaxis protein McpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01506 BL14DL4_01507 BL14DL4_01507 BL14DL4_01507 1373328 1375310 - Methyl-accepting chemotaxis protein McpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01507 BL14DL4_01508 BL14DL4_01508 BL14DL4_01508 1375432 1376178 + Protein-glutamine gamma-glutamyltransferase Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links%3B Belongs to the bacillus TGase family%3B KEGG: bli:BL02523 protein-glutamine gamma-glutamyltransferase gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01508 BL14DL4_01509 BL14DL4_01509 ncd2 ncd2 1376158 1377213 - Nitronate monooxygenase Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites%3B Belongs to the nitronate monooxygenase family%3B KEGG: bli:BL02583 nitronate monooxygenase gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01509 BL14DL4_01510 BL14DL4_01510 BL14DL4_01510 1377229 1377630 - Nitronate monooxygenase Belongs to the UPF0047 family%3B KEGG: bao:BAMF_2926 nitronate monooxygenase__ gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01510 BL14DL4_01511 BL14DL4_01511 BL14DL4_01511 1377669 1379351 - Alpha-glucosidase Belongs to the glycosyl hydrolase 13 family%3B KEGG: aza:AZKH_2678 alpha-glucosidase__ gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01511 BL14DL4_01512 BL14DL4_01512 BL14DL4_01512 1379654 1380244 + hypothetical protein gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01512 BL14DL4_01513 BL14DL4_01513 BL14DL4_01513 1380241 1380915 + uncharacterized protein gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01513 BL14DL4_01514 BL14DL4_01514 BL14DL4_01514 1380998 1381783 - Xyloglucan-specific endo-beta-1%2C4-glucanase Belongs to the glycosyl hydrolase 12 (cellulase H) family%3B KEGG: tre:TRIREDRAFT_123232 xyloglucan-specific endo-beta-1%2C4-glucanase__ gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01514 BL14DL4_01515 BL14DL4_01515 BL14DL4_01515 1381964 1383253 - UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01515 BL14DL4_01516 BL14DL4_01516 BL14DL4_01516 1383304 1383984 - Putative membrane protease YugP gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01516 BL14DL4_01517 BL14DL4_01517 BL14DL4_01517 1384078 1384254 - hypothetical protein gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01517 BL14DL4_01518 BL14DL4_01518 BL14DL4_01518 1384485 1384739 + Protein mistic Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01518 BL14DL4_01519 BL14DL4_01519 BL14DL4_01519 1384736 1385719 + Putative potassium channel protein YugO Contains 1 RCK N-terminal domain gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01519 BL14DL4_01520 BL14DL4_01520 BL14DL4_01520 1385716 1386120 - uncharacterized protein gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01520 BL14DL4_01521 BL14DL4_01521 BL14DL4_01521 1386159 1386725 - UPF0702 transmembrane protein YdfR Belongs to the UPF0702 family gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01521 BL14DL4_01522 BL14DL4_01522 BL14DL4_01522 1386843 1387319 + putative membrane protein YtaB Belongs to the TspO/BZRP family gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01522 BL14DL4_01523 BL14DL4_01523 BL14DL4_01523 1387388 1387897 + Ribosomal-protein-alanine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: chz:CHSO_2638 ribosomal-protein-alanine N-acetyltransferase__ gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01523 BL14DL4_01524 BL14DL4_01524 BL14DL4_01524 1388229 1388840 + hypothetical protein gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01524 BL14DL4_01525 BL14DL4_01525 BL14DL4_01525 1388934 1389302 + SPBc2 prophage-derived uncharacterized protein YolD gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01525 BL14DL4_01526 BL14DL4_01526 BL14DL4_01526 1389326 1389556 - hypothetical protein gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01526 BL14DL4_01527 BL14DL4_01527 BL14DL4_01527 1389811 1389954 - hypothetical protein gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01527 BL14DL4_01528 BL14DL4_01528 BL14DL4_01528 1390107 1391216 + hypothetical protein gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01528 BL14DL4_01529 BL14DL4_01529 BL14DL4_01529 1391471 1392550 - N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01529 BL14DL4_01530 BL14DL4_01530 BL14DL4_01530 1392602 1392865 - putative 9.7 kDa protein in cwlL 5'region Belongs to the SPP1 holin family gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01530 BL14DL4_01531 BL14DL4_01531 BL14DL4_01531 1392881 1393150 - putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01531 BL14DL4_01532 BL14DL4_01532 BL14DL4_01532 1393213 1393395 - hypothetical protein gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01532 BL14DL4_01533 BL14DL4_01533 BL14DL4_01533 1393392 1393706 - hypothetical protein gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01533 BL14DL4_01534 BL14DL4_01534 BL14DL4_01534 1393718 1395061 - Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01534 BL14DL4_01535 BL14DL4_01535 BL14DL4_01535 1395082 1397037 - hypothetical protein gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01535 BL14DL4_01536 BL14DL4_01536 BL14DL4_01536 1397073 1398782 - N-acetylmuramoyl-L-alanine amidase Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: smu:SMU_76 N-acetylmuramoyl-L-alanine amidase__ gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01536 BL14DL4_01537 BL14DL4_01537 BL14DL4_01537 1398794 1399630 - hypothetical protein gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01537 BL14DL4_01538 BL14DL4_01538 BL14DL4_01538 1399630 1403520 - Tape measure protein Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01538 BL14DL4_01539 BL14DL4_01539 BL14DL4_01539 1403718 1404053 - hypothetical protein gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01539 BL14DL4_01540 BL14DL4_01540 BL14DL4_01540 1404113 1404721 - hypothetical protein gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01540 BL14DL4_01541 BL14DL4_01541 BL14DL4_01541 1404721 1405101 - hypothetical protein gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01541 BL14DL4_01542 BL14DL4_01542 BL14DL4_01542 1405098 1405481 - hypothetical protein gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01542 BL14DL4_01543 BL14DL4_01543 BL14DL4_01543 1405778 1406128 - hypothetical protein gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01543 BL14DL4_01544 BL14DL4_01544 BL14DL4_01544 1406144 1406593 - Collagen alpha-1(V) chain Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA%2C heparan sulfate%2C thrombospondin%2C heparin%2C and insulin (By similarity)%3B Belongs to the fibrillar collagen family%3B Contains 1 fibrillar collagen NC1 domain%3B Contains 1 laminin G-like domain gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01544 BL14DL4_01545 BL14DL4_01545 BL14DL4_01545 1406619 1406912 - hypothetical protein gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01545 BL14DL4_01546 BL14DL4_01546 BL14DL4_01546 1406929 1408134 - hypothetical protein gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01546 BL14DL4_01547 BL14DL4_01547 BL14DL4_01547 1408174 1408803 - hypothetical protein gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01547 BL14DL4_01548 BL14DL4_01548 BL14DL4_01548 1408793 1410040 - hypothetical protein gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01548 BL14DL4_01549 BL14DL4_01549 BL14DL4_01549 1410046 1410216 - hypothetical protein gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01549 BL14DL4_01550 BL14DL4_01550 BL14DL4_01550 1410228 1411937 - uncharacterized protein Belongs to the phage terminase family gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01550 BL14DL4_01551 BL14DL4_01551 BL14DL4_01551 1411937 1412470 - hypothetical protein gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01551 BL14DL4_01552 BL14DL4_01552 BL14DL4_01552 1412557 1412883 - hypothetical protein gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01552 BL14DL4_01553 BL14DL4_01553 BL14DL4_01553 1413396 1413623 - hypothetical protein gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01553 BL14DL4_01554 BL14DL4_01554 BL14DL4_01554 1413844 1414068 - Spore coat protein gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01554 BL14DL4_01555 BL14DL4_01555 BL14DL4_01555 1414819 1415199 - hypothetical protein gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01555 BL14DL4_01556 BL14DL4_01556 BL14DL4_01556 1415347 1416156 - Site-specific DNA-methyltransferase (adenine-specific) KEGG: bsn:BSn5_14680 DNA adenine methylase__ gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01556 BL14DL4_01557 BL14DL4_01557 BL14DL4_01557 1416138 1417073 - DNA (cytosine-5-)-methyltransferase This methylase may recognize the double-stranded sequence CTCGAG%2C causing specific methylation on C-? on both strands%2C and protects the DNA from cleavage by the BsuMI endonuclease%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: bss:BSUW23_09675 DNA (cytosine-5)-methyltransferase 1__ gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01557 BL14DL4_01558 BL14DL4_01558 BL14DL4_01558 1417096 1417626 - hypothetical protein gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01558 BL14DL4_01559 BL14DL4_01559 BL14DL4_01559 1417623 1417793 - hypothetical protein gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01559 BL14DL4_01560 BL14DL4_01560 BL14DL4_01560 1417790 1418329 - hypothetical protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01560 BL14DL4_01561 BL14DL4_01561 BL14DL4_01561 1418326 1418763 - hypothetical protein gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01561 BL14DL4_01562 BL14DL4_01562 BL14DL4_01562 1419004 1421430 - Putative helicase L207/L206 Contains 1 SF3 helicase domain gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01562 BL14DL4_01563 BL14DL4_01563 BL14DL4_01563 1421491 1421931 - hypothetical protein gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01563 BL14DL4_01564 BL14DL4_01564 BL14DL4_01564 1421931 1422863 - hypothetical protein gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01564 BL14DL4_01565 BL14DL4_01565 BL14DL4_01565 1422867 1423424 - hypothetical protein gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01565 BL14DL4_01566 BL14DL4_01566 BL14DL4_01566 1423490 1423780 - hypothetical protein gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01566 BL14DL4_01567 BL14DL4_01567 BL14DL4_01567 1423740 1423856 - hypothetical protein gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01567 BL14DL4_01568 BL14DL4_01568 BL14DL4_01568 1423853 1424119 - hypothetical protein gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01568 BL14DL4_01569 BL14DL4_01569 BL14DL4_01569 1424137 1424304 - hypothetical protein gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01569 BL14DL4_01570 BL14DL4_01570 BL14DL4_01570 1424333 1424602 - hypothetical protein gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01570 BL14DL4_01571 BL14DL4_01571 BL14DL4_01571 1424608 1424799 - hypothetical protein gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01571 BL14DL4_01572 BL14DL4_01572 BL14DL4_01572 1425061 1425498 + hypothetical protein gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01572 BL14DL4_01573 BL14DL4_01573 BL14DL4_01573 1425507 1425929 + putative immunity region protein gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01573 BL14DL4_01574 BL14DL4_01574 BL14DL4_01574 1425974 1427122 + ICEBs1 integrase Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome%2C attB%2C and a site in the circular form of ICEBs1%2C attICEBs1%3B Belongs to the 'phage' integrase family gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01574 BL14DL4_01575 BL14DL4_01575 BL14DL4_01575 1427207 1428559 - Glucose-6-phosphate isomerase Belongs to the GPI family%3B KEGG: bsu:BSU31350 glucose-6-phosphate isomerase gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01575 BL14DL4_01576 BL14DL4_01576 BL14DL4_01576 1428849 1430012 - putative NADH-dependent butanol dehydrogenase Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bsu:BSU31370 null%3B With NAD(+) or NADP(+) as acceptor gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01576 BL14DL4_01577 BL14DL4_01577 BL14DL4_01577 1430155 1430391 + putative membrane protein YuzA gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01577 BL14DL4_01578 BL14DL4_01578 BL14DL4_01578 1430624 1431013 - General stress protein Contains 1 S1 motif domain gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01578 BL14DL4_01579 BL14DL4_01579 BL14DL4_01579 1431217 1432389 - Putative aminotransferase YugH Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02594 aminotransferase%3B Transaminases gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01579 BL14DL4_01580 BL14DL4_01580 BL14DL4_01580 1432390 1432890 - putative HTH-type transcriptional regulator YugG Contains 1 HTH asnC-type DNA-binding domain gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01580 BL14DL4_01581 BL14DL4_01581 dhaA dhaA 1433095 1433916 + Haloalkane dehalogenase Belongs to the DmpD/TodF/XylF esterase family%3B KEGG: hme:HFX_2390 haloalkane dehalogenase__ gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01581 BL14DL4_01582 BL14DL4_01582 BL14DL4_01582 1433956 1434213 - uncharacterized protein gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01582 BL14DL4_01583 BL14DL4_01583 BL14DL4_01583 1434290 1434787 - hypothetical protein gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01583 BL14DL4_01584 BL14DL4_01584 patB patB 1434894 1436057 + Cystathionine beta-lyase Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily%3B KEGG: bli:BL02532 cystathione beta-lyase gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01584 BL14DL4_01585 BL14DL4_01585 BL14DL4_01585 1436084 1436284 - hypothetical protein gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01585 BL14DL4_01586 BL14DL4_01586 BL14DL4_01586 1436352 1436741 + Kinase-associated lipoprotein gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01586 BL14DL4_01587 BL14DL4_01587 BL14DL4_01587 1436769 1437386 - putative 3'-5' exonuclease KapD Specifically inhibits the KinA pathway to sporulation%3B Contains 1 exonuclease domain gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01587 BL14DL4_01588 BL14DL4_01588 BL14DL4_01588 1437605 1438876 + putative MFS-type transporter YuxJ Belongs to the major facilitator superfamily gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01588 BL14DL4_01589 BL14DL4_01589 BL14DL4_01589 1439010 1440845 + Penicillin-binding protein In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01589 BL14DL4_01590 BL14DL4_01590 nagA nagA 1440869 1441276 + Alpha-N-acetylgalactosaminidase Belongs to the DCC thiol-disulfide oxidoreductase family%3B KEGG: dfa:DFA_08734 alpha-N-acetylgalactosaminidase__ gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01590 BL14DL4_01591 BL14DL4_01591 BL14DL4_01591 1441327 1441884 - putative membrane protein YufK gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01591 BL14DL4_01592 BL14DL4_01592 yufL yufL 1442071 1443672 + Histidine kinase Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA%2C maeN and yflS in presence of malate. Probably activates MalR by phosphorylation%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU31520 two-component system%2C CitB family%2C sensor histidine kinase MalK gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01592 BL14DL4_01593 BL14DL4_01593 BL14DL4_01593 1443665 1444372 + Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01593 BL14DL4_01594 BL14DL4_01594 cho1 cho1 1444927 1445463 + CDP-diacylglycerol--serine O-phosphatidyltransferase Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bli:BL02540 CDP-diacylglycerol---serine O-phosphatidyltransferase gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01594 BL14DL4_01595 BL14DL4_01595 BL14DL4_01595 1445470 1445952 + putative membrane protein YbfM Belongs to the DedA family gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01595 BL14DL4_01596 BL14DL4_01596 pisD pisD 1445995 1446786 + Phosphatidylserine decarboxylase Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily%3B KEGG: bli:BL02542 phosphatidylserine decarboxylase gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01596 BL14DL4_01597 BL14DL4_01597 BL14DL4_01597 1447059 1448402 + Na(+)-malate symporter Acts as a Na(+)-malate symporter%2C as it catalyzes malate-dependent uptake of Na(+) and Na(+)-dependent uptake of malate%3B Belongs to the sodium:citrate (SCF) symporter family gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01597 BL14DL4_01598 BL14DL4_01598 BL14DL4_01598 1448462 1448695 - hypothetical protein gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01598 BL14DL4_01599 BL14DL4_01599 BL14DL4_01599 1448941 1451343 + Na(+)/H(+) antiporter subunit A1 Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit A family gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01599 BL14DL4_01600 BL14DL4_01600 BL14DL4_01600 1451340 1451771 + Na(+)/H(+) antiporter subunit Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential%2C and is thus inferred to be electrogenic. Does not transport K(+)%2C Ca(2+) or Mg(2+). Belongs to the CPA3 antiporters (TC 2. A. 63) subunit B family gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01600 BL14DL4_01601 BL14DL4_01601 BL14DL4_01601 1451771 1452112 + Na(+)/H(+) antiporter subunit C1 Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit C family gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01601 BL14DL4_01602 BL14DL4_01602 BL14DL4_01602 1452096 1453583 + Putative antiporter subunit mnhD2 Belongs to the CPA3 antiporters (TC 2. A. 63) subunit D family gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01602 BL14DL4_01603 BL14DL4_01603 BL14DL4_01603 1453589 1454065 + Na(+)/H(+) antiporter subunit E1 Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion%3B Belongs to the CPA3 antiporters (TC 2. A. 63) subunit E family gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01603 BL14DL4_01604 BL14DL4_01604 BL14DL4_01604 1454065 1454349 + Na(+)/H(+) antiporter subunit Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Involved in cholate and Na(+) efflux activities%2C which may be mechanistically coupled. Does not require other Mrp proteins for its own function. Belongs to the CPA3 antiporters (TC 2. A. 63) subunit F family gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01604 BL14DL4_01605 BL14DL4_01605 BL14DL4_01605 1454333 1454707 + Na(+)/H(+) antiporter subunit May enhance MrpA stability%2C assembly%2C or function. May play chaperone or assembly roles for MrpA and perhaps for other mrp proteins. Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter%2C although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+)%2C Ca(2+) or Mg(2+). Belongs to the CPA3 antiporters (TC 2. A. 63) subunit G family gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01605 BL14DL4_01606 BL14DL4_01606 menI menI 1454747 1455139 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase Is not required for competence. Belongs to the thioesterase PaaI family%3B KEGG: eal:EAKF1_ch4366 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase__ gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01606 BL14DL4_01607 BL14DL4_01607 BL14DL4_01607 1455153 1455791 - Transcriptional regulatory protein ComA Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes%2C including genes of the srfA operon%2C degQ%2C rapA%2C rapC%2C rapE%2C rapF%2C etc. Regulates indirectly%2C through the regulation of comK transcription%2C the expression of late competence genes%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01607 BL14DL4_01608 BL14DL4_01608 comP comP 1455878 1458184 - Histidine kinase Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation%2C at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bao:BAMF_2968 two-component system%2C NarL family%2C sensor histidine kinase ComP__ gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01608 BL14DL4_01609 BL14DL4_01609 BL14DL4_01609 1458207 1458371 - hypothetical protein gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01609 BL14DL4_01610 BL14DL4_01610 BL14DL4_01610 1458380 1459261 - Competence regulatory protein ComQ Involved in the maturation of ComX%2C part of a major quorum-sensing system that regulates the development of genetic competence gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01610 BL14DL4_01611 BL14DL4_01611 BL14DL4_01611 1459450 1459590 - Degradation enzyme regulation protein DegQ Stimulates the phosphotransfer from phospho-DegS to DegU. Affects protease and levansucrose production (By similarity)%3B Belongs to the DegQ family gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01611 BL14DL4_01612 BL14DL4_01612 BL14DL4_01612 1459868 1460083 - hypothetical protein gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01612 BL14DL4_01613 BL14DL4_01613 BL14DL4_01613 1460085 1460423 + uncharacterized protein gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01613 BL14DL4_01614 BL14DL4_01614 BL14DL4_01614 1460466 1461686 - uncharacterized protein Contains 1 EAL domain gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01614 BL14DL4_01615 BL14DL4_01615 pncB pncB 1461865 1463334 - Nicotinate phosphoribosyltransferase Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN)%3B Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP%3B Belongs to the NAPRTase family%3B KEGG: bli:BL02611 nicotinate phosphoribosyltransferase gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01615 BL14DL4_01616 BL14DL4_01616 BL14DL4_01616 1463352 1463903 - putative isochorismatase family protein PncA Belongs to the isochorismatase family gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01616 BL14DL4_01617 BL14DL4_01617 BL14DL4_01617 1464088 1464489 - uncharacterized protein gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01617 BL14DL4_01618 BL14DL4_01618 BL14DL4_01618 1464584 1464832 - uncharacterized protein gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01618 BL14DL4_01619 BL14DL4_01619 BL14DL4_01619 1464906 1465127 - Spore germination protein-like protein YueG Belongs to the GerPA/GerPF family gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01619 BL14DL4_01620 BL14DL4_01620 BL14DL4_01620 1465184 1466293 - UPF0118 membrane protein YueF Belongs to the UPF0118 (PerM) family gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01620 BL14DL4_01621 BL14DL4_01621 BL14DL4_01621 1466482 1466916 + Putative HTH-type transcriptional regulator YwnA Contains 1 HTH rrf2-type DNA-binding domain gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01621 BL14DL4_01622 BL14DL4_01622 BL14DL4_01622 1467087 1467983 + hypothetical protein gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01622 BL14DL4_01623 BL14DL4_01623 BL14DL4_01623 1468129 1469592 + hypothetical protein gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01623 BL14DL4_01624 BL14DL4_01624 BL14DL4_01624 1469589 1470119 - Putative phosphohydrolase YueE Contains 1 HD domain gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01624 BL14DL4_01625 BL14DL4_01625 yueD yueD 1470256 1470987 - Benzil reductase ((S)-benzoin forming) Reduces benzil stereospecifically to (S)-benzoin%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02617 benzil reductase ((S)-benzoin forming) gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01625 BL14DL4_01626 BL14DL4_01626 BL14DL4_01626 1471134 1471622 - hypothetical protein gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01626 BL14DL4_01627 BL14DL4_01627 BL14DL4_01627 1471612 1474641 - Bacteriophage SPP1 adsorption protein YueB Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01627 BL14DL4_01628 BL14DL4_01628 BL14DL4_01628 1474638 1479122 - Ftsk domain-containing protein YukB Contains 2 FtsK domains gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01628 BL14DL4_01629 BL14DL4_01629 BL14DL4_01629 1479159 1480475 - uncharacterized protein Belongs to the EssB family gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01629 BL14DL4_01630 BL14DL4_01630 BL14DL4_01630 1480490 1480729 - putative ubiquitin-like protein YukD gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01630 BL14DL4_01631 BL14DL4_01631 BL14DL4_01631 1480810 1481106 - Virulence factor EsxA Virulence factor that is important for the establishment of infection in the host%3B Belongs to the ESAT-6 (esx) family gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01631 BL14DL4_01632 BL14DL4_01632 BL14DL4_01632 1481439 1482848 - Sodium/alanine symporter AgcS Probably functions as a sodium/L- and D-alanine symporter for alanine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01632 BL14DL4_01633 BL14DL4_01633 BL14DL4_01633 1483031 1484269 + Transcriptional activator AdeR Mediates ald expression in response to alanine availability and is important for normal sporulation in B. subtilis%3B Belongs to the CdaR family gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01633 BL14DL4_01634 BL14DL4_01634 pntA pntA 1484380 1485519 + NAD(P)(+) transhydrogenase (Re/Si-specific) May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01634 BL14DL4_01635 BL14DL4_01635 BL14DL4_01635 1485570 1485815 - hypothetical protein gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01635 BL14DL4_01636 BL14DL4_01636 yedY yedY 1485830 1486423 - putative oxidoreductase YuiH KEGG: bli:BL05322 sulfoxide reductase catalytic subunit YedY%3B Acting on a sulfur group of donors gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01636 BL14DL4_01637 BL14DL4_01637 BL14DL4_01637 1486526 1487122 + Putative biotin transporter BioYB Putative biotin transporter%3B Belongs to the BioY family gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01637 BL14DL4_01638 BL14DL4_01638 BL14DL4_01638 1487202 1488530 - Putative amino acid transporter YuiF gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01638 BL14DL4_01639 BL14DL4_01639 carP carP 1488682 1490172 - Leucyl aminopeptidase Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides%3B Belongs to the peptidase M17 family%3B KEGG: bli:BL05323 leucyl aminopeptidase gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01639 BL14DL4_01640 BL14DL4_01640 BL14DL4_01640 1490338 1490814 + putative membrane protein YuiD gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01640 BL14DL4_01641 BL14DL4_01641 BL14DL4_01641 1490857 1491531 - uncharacterized protein gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01641 BL14DL4_01642 BL14DL4_01642 BL14DL4_01642 1491658 1491987 - putative membrane protein YuiB gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01642 BL14DL4_01643 BL14DL4_01643 BL14DL4_01643 1492491 1493702 - NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: bsu:BSU32100 NADH dehydrogenase gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01643 BL14DL4_01644 BL14DL4_01644 BL14DL4_01644 1494047 1495045 + Thioredoxin-disulfide reductase Belongs to the ferredoxin--NADP reductase type 2 family%3B KEGG: bsu:BSU32110 thioredoxin reductase (NADPH) gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01644 BL14DL4_01645 BL14DL4_01645 BL14DL4_01645 1495080 1495280 - hypothetical protein gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01645 BL14DL4_01646 BL14DL4_01646 BL14DL4_01646 1495423 1495647 + uncharacterized protein gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01646 BL14DL4_01647 BL14DL4_01647 BL14DL4_01647 1495742 1496296 - DNA-3-methyladenine glycosylase I Contains 1 N-acetyltransferase domain%3B KEGG: bha:BH1453 DNA-3-methyladenine glycosylase I gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01647 BL14DL4_01648 BL14DL4_01648 BL14DL4_01648 1496317 1496682 - Iron-sulfur cluster insertion protein ErpA Required for insertion of 4Fe-4S clusters for at least IspG%3B Belongs to the HesB/IscA family gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01648 BL14DL4_01649 BL14DL4_01649 dapF dapF 1496757 1497614 - Diaminopimelate epimerase Catalyzes the stereoinversion of LL-2%2C6- diaminoheptanedioate (L%2CL-DAP) to meso-diaminoheptanedioate (meso- DAP)%2C a precursor of L-lysine and an essential component of the bacterial peptidoglycan%3B Belongs to the diaminopimelate epimerase family%3B KEGG: bsu:BSU32170 diaminopimelate epimerase gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01649 BL14DL4_01650 BL14DL4_01650 BL14DL4_01650 1497740 1498957 - putative transporter YutK Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01650 BL14DL4_01651 BL14DL4_01651 BL14DL4_01651 1499114 1499350 - UPF0349 protein Belongs to the UPF0349 family gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01651 BL14DL4_01652 BL14DL4_01652 BL14DL4_01652 1499624 1500691 + NADH dehydrogenase Belongs to the NADH dehydrogenase family%3B KEGG: blh:BaLi_c34690 NADH dehydrogenase__ gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01652 BL14DL4_01653 BL14DL4_01653 BL14DL4_01653 1500799 1501170 - Intracellular iron chaperone frataxin Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron-sulfur cluster assembly scaffold protein SufU. In the presence of SufS and L-cysteine reconstitutes Fe-S clusters on SufU%2C which when further incubated with apo-aconitase (citB) reconstitutes aconitase activity. Able to reconstitute an Fe-S cluster on Thermotoga maritima IscU gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01653 BL14DL4_01654 BL14DL4_01654 BL14DL4_01654 1501499 1501690 - hypothetical protein gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01654 BL14DL4_01655 BL14DL4_01655 BL14DL4_01655 1501687 1502793 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02337 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01655 BL14DL4_01656 BL14DL4_01656 BL14DL4_01656 1503070 1503570 + Phenolic acid decarboxylase PadC Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic%2C p-coumaric and caffeic acids%3B Belongs to the PadC family%3B KEGG: bli:BL02117 phenolic acid decarboxylase%3B Carboxy-lyases gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01656 BL14DL4_01657 BL14DL4_01657 BL14DL4_01657 1503580 1503846 - hypothetical protein gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01657 BL14DL4_01658 BL14DL4_01658 BL14DL4_01658 1503957 1504283 - Putative disulfide oxidoreductase YuzD gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01658 BL14DL4_01659 BL14DL4_01659 BL14DL4_01659 1504476 1504715 + Putative nitrogen fixation protein YutI May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins%3B Belongs to the NifU family gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01659 BL14DL4_01660 BL14DL4_01660 apeH apeH 1504952 1506913 - Acylaminoacyl-peptidase Belongs to the peptidase S9B family%3B KEGG: bce:BC0192 acylaminoacyl-peptidase gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01660 BL14DL4_01661 BL14DL4_01661 BL14DL4_01661 1507020 1507940 - Homoserine kinase Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate%3B Belongs to the GHMP kinase family. Homoserine kinase subfamily%3B KEGG: bsu:BSU32240 homoserine kinase gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01661 BL14DL4_01662 BL14DL4_01662 thrC thrC 1507937 1509004 - Threonine synthase Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine%3B Belongs to the threonine synthase family%3B KEGG: bsl:A7A1_2331 threonine synthase__ gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01662 BL14DL4_01663 BL14DL4_01663 BL14DL4_01663 1508995 1510296 - Homoserine dehydrogenase Belongs to the homoserine dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: seds:AAY24_06030 homoserine dehydrogenase__ gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01663 BL14DL4_01664 BL14DL4_01664 gyaR gyaR 1510530 1511492 - Glyoxylate reductase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily%3B KEGG: bmq:BMQ_4977 glyoxylate reductase__ gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01664 BL14DL4_01665 BL14DL4_01665 BL14DL4_01665 1511582 1512604 - Endospore coat-associated protein YutH Involved in sporulation%3B Belongs to the CotS family gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01665 BL14DL4_01666 BL14DL4_01666 BL14DL4_01666 1512755 1513237 + Phosphatidylglycerophosphatase To B. subtilis YutG%3B KEGG: bpu:BPUM_1917 phosphatidylglycerophosphatase A__ gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01666 BL14DL4_01667 BL14DL4_01667 BL14DL4_01667 1513283 1514053 - 4-nitrophenylphosphatase Belongs to the HAD-like hydrolase superfamily%3B KEGG: bsu:BSU32290 4-nitrophenyl phosphatase gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01667 BL14DL4_01668 BL14DL4_01668 BL14DL4_01668 1514073 1514516 - UPF0331 protein YutE Belongs to the UPF0331 family gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01668 BL14DL4_01669 BL14DL4_01669 BL14DL4_01669 1514541 1514816 - uncharacterized protein gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01669 BL14DL4_01670 BL14DL4_01670 BL14DL4_01670 1514919 1515542 + putative lipoprotein YutC gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01670 BL14DL4_01671 BL14DL4_01671 lipA lipA 1515596 1516492 - Lipoyl synthase Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes%2C thereby converting the octanoylated domains into lipoylated derivatives%3B Belongs to the radical SAM superfamily. Lipoyl synthase family%3B KEGG: bsu:BSU32330 lipoic acid synthetase gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01671 BL14DL4_01672 BL14DL4_01672 BL14DL4_01672 1516745 1517725 + L-Ala--D-Glu endopeptidase L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore%2C is required for the endospore cortex maturation%3B Belongs to the peptidase M23B family gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01672 BL14DL4_01673 BL14DL4_01673 BL14DL4_01673 1517774 1517887 - hypothetical protein gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01673 BL14DL4_01674 BL14DL4_01674 BL14DL4_01674 1517884 1519413 - putative sodium-dependent transporter YhdH Putative sodium-dependent transporter%3B Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01674 BL14DL4_01675 BL14DL4_01675 BL14DL4_01675 1519599 1520372 - Sporulation protein YunB Required for sporulation gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01675 BL14DL4_01676 BL14DL4_01676 BL14DL4_01676 1520440 1520745 - uncharacterized protein gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01676 BL14DL4_01677 BL14DL4_01677 BL14DL4_01677 1520823 1522178 - 5'-nucleotidase Belongs to the metallophosphoesterase superfamily%3B KEGG: llm:llmg_0192 5'-nucleotidase__ gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01677 BL14DL4_01678 BL14DL4_01678 BL14DL4_01678 1522198 1523019 - UPF0721 transmembrane protein YunE Belongs to the UPF0721 family gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01678 BL14DL4_01679 BL14DL4_01679 BL14DL4_01679 1523037 1523888 - UPF0759 protein YunF Belongs to the UPF0759 family gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01679 BL14DL4_01680 BL14DL4_01680 BL14DL4_01680 1524020 1524553 - putative membrane protein YmcC gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01680 BL14DL4_01681 BL14DL4_01681 BL14DL4_01681 1524644 1525228 + HTH-type transcriptional regulator PksA Transcriptional regulation of the polyketide synthase operon. Contains 1 HTH tetR-type DNA-binding domain gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01681 BL14DL4_01682 BL14DL4_01682 BL14DL4_01682 1525417 1525638 - hypothetical protein gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01682 BL14DL4_01683 BL14DL4_01683 pucG pucG 1526147 1527373 - Purine catabolism protein PucG Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase%2C or perhaps both activities%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02152 (S)-ureidoglycine-glyoxylate aminotransferase%3B Transaminases gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01683 BL14DL4_01684 BL14DL4_01684 allC allC 1527389 1528642 - Allantoate deiminase Involved in the anaerobic utilization of allantoin. Converts allantoate to (S)-ureidoglycolate and ammonia%3B Belongs to the peptidase M20 family%3B KEGG: bli:BL02153 allantoate deiminase gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01684 BL14DL4_01685 BL14DL4_01685 BL14DL4_01685 1528807 1530405 + Purine catabolism regulatory protein Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01685 BL14DL4_01686 BL14DL4_01686 BL14DL4_01686 1530508 1531704 - Multidrug resistance protein Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances%2C including such structurally diverse compounds as ethidium bromide%2C rhodamine and acridine dyes%2C tetraphenylphosphonium%2C puromycin%2C chloramphenicol%2C doxorubicin%2C and fluoroquinolone antibiotics. Belongs to the major facilitator superfamily. TCR/Tet family gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01686 BL14DL4_01687 BL14DL4_01687 BL14DL4_01687 1531883 1533289 - uncharacterized protein To E. coli YfcC and H. influenzae HI_594__ gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01687 BL14DL4_01688 BL14DL4_01688 BL14DL4_01688 1533533 1534267 + Anthranilate phosphoribosyltransferase Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)%3B Belongs to the anthranilate phosphoribosyltransferase family%3B KEGG: blh:BaLi_c35040 anthranilate phosphoribosyltransferase__ gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01688 BL14DL4_01689 BL14DL4_01689 BL14DL4_01689 1534231 1534578 + Anthranilate phosphoribosyltransferase KEGG: blh:BaLi_c35040 anthranilate phosphoribosyltransferase__ gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01689 BL14DL4_01690 BL14DL4_01690 BL14DL4_01690 1534658 1535470 + Extracellular ribonuclease Mg(2+)-activated ribonuclease which hydrolyzes RNA apparently nonspecifically into oligonucleotides with 5'-terminal phosphate gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01690 BL14DL4_01691 BL14DL4_01691 ygeS ygeS 1535761 1536600 - Xanthine dehydrogenase KEGG: bce:BC3167 xanthine dehydrogenase molybdenum-binding subunit gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01691 BL14DL4_01692 BL14DL4_01692 dadA dadA 1536801 1537922 - D-arginine dehydrogenase Belongs to the DadA oxidoreductase family%3B KEGG: bsu:BSU32630 D-amino-acid dehydrogenase gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01692 BL14DL4_01693 BL14DL4_01693 BL14DL4_01693 1537988 1538848 - hypothetical protein gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01693 BL14DL4_01694 BL14DL4_01694 BL14DL4_01694 1538879 1539262 - hypothetical protein gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01694 BL14DL4_01695 BL14DL4_01695 BL14DL4_01695 1539546 1539719 - hypothetical protein gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01695 BL14DL4_01696 BL14DL4_01696 BL14DL4_01696 1539850 1540965 - Response regulator aspartate phosphatase J Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bli:BL02161 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01696 BL14DL4_01697 BL14DL4_01697 BL14DL4_01697 1541412 1542809 - FeS cluster assembly protein SufB The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01697 BL14DL4_01698 BL14DL4_01698 BL14DL4_01698 1542828 1543274 - Zinc-dependent sulfurtransferase SufU Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein (PubMed:20097860%2C PubMed:21236255)%2C but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein (PubMed:24321018). Has been shown to bind low levels of a labile%2C air-sensitive Fe-S cluste%3B this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS%2C for which it acts as a second substrate. Alkylation eliminates its ability to stimulate SufS. A mixture of SufS%2C SufU%2C Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB)%2C reconstituting aconitase activity%3B Belongs to the NifU family gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01698 BL14DL4_01699 BL14DL4_01699 sufS sufS 1543264 1544484 - Cysteine desulfurase Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine%2C an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon%2C which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro%2C that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily%3B KEGG: bli:BL02164 cysteine desulfurase / selenocysteine lyase gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01699 BL14DL4_01700 BL14DL4_01700 BL14DL4_01700 1544484 1545797 - FeS cluster assembly protein SufD The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity)%3B Belongs to the UPF0051 (ycf24) family gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01700 BL14DL4_01701 BL14DL4_01701 BL14DL4_01701 1545815 1546600 - Vegetative protein 296 Belongs to the ABC transporter superfamily. Ycf16 family%3B Contains 1 ABC transporter domain gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01701 BL14DL4_01702 BL14DL4_01702 BL14DL4_01702 1546829 1547764 - Cadmium%2C cobalt and zinc/H(+)-K(+) antiporter Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc%2C cadmium and cobalt%2C in exchange for potassium and H(+) ions (By similarity)%3B Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family. SLC30A subfamily gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01702 BL14DL4_01703 BL14DL4_01703 pcaC pcaC 1548185 1548553 - 4-carboxymuconolactone decarboxylase KEGG: bca:BCE_2858 4-carboxymuconolactone decarboxylase__ gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01703 BL14DL4_01704 BL14DL4_01704 BL14DL4_01704 1548660 1549490 - Methionine-binding lipoprotein MetQ Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable)%3B Belongs to the NlpA lipoprotein family gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01704 BL14DL4_01705 BL14DL4_01705 BL14DL4_01705 1549504 1550172 - Methionine import system permease protein MetP Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01705 BL14DL4_01706 BL14DL4_01706 macB macB 1550165 1551190 - Lipoprotein-releasing system ATP-binding protein LolD Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone%2C LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner%3B Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3. A. 1. 125) family%3B Contains 1 ABC transporter domain%3B KEGG: yen:YE1199 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01706 BL14DL4_01707 BL14DL4_01707 BL14DL4_01707 1551598 1551945 - uncharacterized protein gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01707 BL14DL4_01708 BL14DL4_01708 BL14DL4_01708 1552067 1552375 - Thioredoxin-like protein YusE Contains 1 thioredoxin domain gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01708 BL14DL4_01709 BL14DL4_01709 BL14DL4_01709 1552401 1552745 - uncharacterized protein Contains 1 Toprim domain gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01709 BL14DL4_01710 BL14DL4_01710 BL14DL4_01710 1552808 1553044 - uncharacterized protein gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01710 BL14DL4_01711 BL14DL4_01711 BL14DL4_01711 1553098 1553481 - Glycine cleavage system H protein The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein%3B Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate%3B Belongs to the GcvH family%3B Contains 1 lipoyl-binding domain gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01711 BL14DL4_01712 BL14DL4_01712 BL14DL4_01712 1553543 1553899 - Arsenate reductase (glutaredoxin) Belongs to the ArsC family%3B KEGG: bli:BL02177 arsenate reductase gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01712 BL14DL4_01713 BL14DL4_01713 BL14DL4_01713 1554019 1555803 - putative acyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcl:ABC2988 null%3B With other acceptors gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01713 BL14DL4_01714 BL14DL4_01714 atoB atoB 1555823 1556998 - Acetyl-CoA C-acetyltransferase Involved in the degradation of long-chain fatty acids. Belongs to the thiolase family%3B KEGG: spe:Spro_4857 acetyl-CoA C-acetyltransferase__ gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01714 BL14DL4_01715 BL14DL4_01715 fadN fadN 1557010 1559400 - 3-hydroxyacyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bsu:BSU32840 3-hydroxyacyl-CoA dehydrogenase gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01715 BL14DL4_01716 BL14DL4_01716 BL14DL4_01716 1559610 1559771 + hypothetical protein gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01716 BL14DL4_01717 BL14DL4_01717 BL14DL4_01717 1559847 1560095 + uncharacterized protein gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01717 BL14DL4_01718 BL14DL4_01718 BL14DL4_01718 1560106 1560447 + uncharacterized protein gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01718 BL14DL4_01719 BL14DL4_01719 BL14DL4_01719 1560477 1560728 - uncharacterized protein gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01719 BL14DL4_01720 BL14DL4_01720 BL14DL4_01720 1560729 1561469 - hypothetical protein gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01720 BL14DL4_01721 BL14DL4_01721 BL14DL4_01721 1561462 1562280 - Iron-chelate-transporting ATPase Provides the ATPase subunit for at least 2 ABC transporter complexe%3B YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen (Probable)%2C and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU32940 iron complex transport system ATP-binding protein gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01721 BL14DL4_01722 BL14DL4_01722 BL14DL4_01722 1562298 1563353 - putative siderophore transport system permease protein YfhA Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01722 BL14DL4_01723 BL14DL4_01723 BL14DL4_01723 1563350 1564351 - putative siderophore transport system permease protein YfiZ Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01723 BL14DL4_01724 BL14DL4_01724 BL14DL4_01724 1564504 1565481 + putative siderophore-binding lipoprotein YfiY Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01724 BL14DL4_01725 BL14DL4_01725 BL14DL4_01725 1565521 1565967 - uncharacterized protein gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01725 BL14DL4_01726 BL14DL4_01726 pepF pepF 1566045 1567829 - Oligoendopeptidase F%2C plasmid Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity. Belongs to the peptidase M3B family%3B KEGG: gbm:Gbem_1295 oligoendopeptidase F%3B Metalloendopeptidases__ gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01726 BL14DL4_01727 BL14DL4_01727 BL14DL4_01727 1567941 1569095 - Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex). Belongs to the peptidase S11 family%3B KEGG: bli:BL05330 D-alanyl-D-alanine carboxypeptidase gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01727 BL14DL4_01728 BL14DL4_01728 BL14DL4_01728 1569236 1570078 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: aad:TC41_1190 3-oxoacyl-(acyl-carrier protein) reductase__ gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01728 BL14DL4_01729 BL14DL4_01729 BL14DL4_01729 1570173 1570637 + Metalloregulation DNA-binding stress protein Forms highly stable%2C multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing. Belongs to the Dps family gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01729 BL14DL4_01730 BL14DL4_01730 degP degP 1570673 1572043 - Peptidase Do Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL00734 serine protease Do gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01730 BL14DL4_01731 BL14DL4_01731 BL14DL4_01731 1572282 1572956 + Transcriptional regulatory protein CssR Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01731 BL14DL4_01732 BL14DL4_01732 cssS cssS 1572953 1574299 + Histidine kinase Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00749 two-component system%2C OmpR family%2C sensor histidine kinase CssS gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01732 BL14DL4_01733 BL14DL4_01733 BL14DL4_01733 1574323 1574487 - uncharacterized protein gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01733 BL14DL4_01734 BL14DL4_01734 BL14DL4_01734 1574606 1575559 + putative HTH-type transcriptional regulator YuxN Contains 1 HTH tetR-type DNA-binding domain gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01734 BL14DL4_01735 BL14DL4_01735 fumC fumC 1575605 1576993 - Fumarate hydratase Catalyzes the reversible addition of water to fumarate to give L-malate%3B Belongs to the class-II fumarase/aspartase family. Fumarase subfamily%3B KEGG: hin:HI1398 fumarate hydratase%2C class II gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01735 BL14DL4_01736 BL14DL4_01736 BL14DL4_01736 1577077 1577244 - uncharacterized protein gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01736 BL14DL4_01737 BL14DL4_01737 BL14DL4_01737 1577368 1578810 + Spore germination protein A1 Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the GerABKA family gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01737 BL14DL4_01738 BL14DL4_01738 BL14DL4_01738 1578779 1579879 + Spore germination protein A2 Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine%2C thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors%2C respectively)%2C but the response is improved in their presence. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01738 BL14DL4_01739 BL14DL4_01739 BL14DL4_01739 1579876 1580997 + Spore germination protein B3 Involved in the response to the germinative mixture of L-asparagine%2C glucose%2C fructose and potassium ions (AGFK). Cannot stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors respectively). Belongs to the GerABKC lipoprotein family gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01739 BL14DL4_01740 BL14DL4_01740 BL14DL4_01740 1581059 1581424 + hypothetical protein gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01740 BL14DL4_01741 BL14DL4_01741 BL14DL4_01741 1581461 1582096 - Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01741 BL14DL4_01742 BL14DL4_01742 liaS liaS 1582100 1583164 - Histidine kinase Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin%2C nisin%2C ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL00729 two-component system%2C NarL family%2C sensor histidine kinase LiaS gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01742 BL14DL4_01743 BL14DL4_01743 BL14DL4_01743 1583161 1583892 - Protein LiaF gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01743 BL14DL4_01744 BL14DL4_01744 BL14DL4_01744 1583923 1584786 - hypothetical protein gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01744 BL14DL4_01745 BL14DL4_01745 BL14DL4_01745 1584892 1585575 - Protein LiaH Belongs to the PspA/IM30 family gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01745 BL14DL4_01746 BL14DL4_01746 BL14DL4_01746 1585596 1585982 - Protein LiaI gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01746 BL14DL4_01747 BL14DL4_01747 BL14DL4_01747 1586155 1587108 - Pectinesterase Acts in the modification of cell walls via demethylesterification of cell wall pectin%3B In the N-terminal sectio%3B belongs to the PMEI family%3B In the C-terminal sectio%3B belongs to the pectinesterase family%3B KEGG: bli:BL00724 pectinesterase gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01747 BL14DL4_01748 BL14DL4_01748 mmaB mmaB 1587239 1587817 - Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase Belongs to the Cob(I)alamin adenosyltransferase family%3B KEGG: bsu:BSU33150 cob(I)alamin adenosyltransferase gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01748 BL14DL4_01749 BL14DL4_01749 BL14DL4_01749 1588003 1588749 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: mbat:BN1208_0787 3-oxoacyl-(acyl-carrier protein) reductase_ gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01749 BL14DL4_01750 BL14DL4_01750 pdxA pdxA 1588786 1589004 - 4-hydroxythreonine-4-phosphate dehydrogenase Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)%3B Belongs to the PdxA family%3B KEGG: eco:b0052 4-hydroxythreonine-4-phosphate dehydrogenase gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01750 BL14DL4_01751 BL14DL4_01751 BL14DL4_01751 1590525 1590580 - Alcohol dehydrogenase%3B nonfunctional due to frameshift pseudo gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01751 BL14DL4_01752 BL14DL4_01752 dapA dapA 1590697 1591599 - 4-hydroxy-tetrahydrodipicolinate synthase Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: msu:MS0282 4-hydroxy-tetrahydrodipicolinate synthase gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01752 BL14DL4_01753 BL14DL4_01753 ccmA ccmA 1591785 1593068 - Heme-transporting ATPase Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose%2C galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3. A. 1. 2) family%3B Contains 2 ABC transporter domains%3B KEGG: pao:Pat9b_2799 heme exporter protein A gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01753 BL14DL4_01754 BL14DL4_01754 BL14DL4_01754 1593061 1594125 - putative ABC transporter permease protein YvrB Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01754 BL14DL4_01755 BL14DL4_01755 BL14DL4_01755 1594088 1595038 - putative ABC transporter substrate-binding lipoprotein YvrC Probably part of an ABC transporter complex%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01755 BL14DL4_01756 BL14DL4_01756 BL14DL4_01756 1595418 1596098 + Nta operon transcriptional regulator Probable regulator for the expression of the NTA monooxygenase subunits. Contains 1 HTH gntR-type DNA-binding domain gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01756 BL14DL4_01757 BL14DL4_01757 BL14DL4_01757 1596197 1596988 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: pjd:Pjdr2_3073 3-oxoacyl-(acyl-carrier protein) reductase gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01757 BL14DL4_01758 BL14DL4_01758 BL14DL4_01758 1597031 1597726 - uncharacterized protein Contains 1 MOSC domain gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01758 BL14DL4_01759 BL14DL4_01759 BL14DL4_01759 1597887 1598795 + Hydrogen peroxide-inducible protein activator Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase%3B Contains 1 HTH lysR-type DNA-binding domain gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01759 BL14DL4_01760 BL14DL4_01760 BL14DL4_01760 1598833 1600143 - Alpha-L-rhamnosidase Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G). Has both epimerase and lyase activities. Contributes to abortive encystment by degrading the coat from inside the cyst. Important for cyst germination. Belongs to the D-mannuronate C5-epimerase family%3B Contains 8 hemolysin-type calcium-binding repeats%3B Contains 9 PbH1 repeats%3B KEGG: vba:IMCC26134_08560 alpha-L-rhamnosidase gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01760 BL14DL4_01761 BL14DL4_01761 uxaA uxaA 1600157 1601647 - Altronate dehydratase Catalyzes the dehydration of D-altronate%3B Belongs to the UxaA family%3B KEGG: bli:BL00712 altronate hydrolase gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01761 BL14DL4_01762 BL14DL4_01762 uxaB uxaB 1601647 1603116 - Tagaturonate reductase Belongs to the mannitol dehydrogenase family. UxaB subfamily%3B KEGG: bli:BL00711 tagaturonate reductase gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01762 BL14DL4_01763 BL14DL4_01763 BL14DL4_01763 1603177 1604175 - Catabolite control protein A Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA)%2C which ensures optimal energy usage under diverse conditions%3B Contains 1 HTH lacI-type DNA-binding domain gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01763 BL14DL4_01764 BL14DL4_01764 BL14DL4_01764 1604255 1605643 - putative symporter YjmB Belongs to the sodium:galactoside symporter (TC 2. A. 2) family gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01764 BL14DL4_01765 BL14DL4_01765 uxaC uxaC 1605679 1607100 - Glucuronate isomerase Belongs to the uronate isomerase family%3B KEGG: eco:b3092 glucuronate isomerase gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01765 BL14DL4_01766 BL14DL4_01766 BL14DL4_01766 1607277 1609034 - Sensor histidine kinase YvrG Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: ban:BA_1118 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01766 BL14DL4_01767 BL14DL4_01767 BL14DL4_01767 1609031 1609759 - Transcriptional regulatory protein YvrH Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA%2C wapA- yxxG%2C dltABCDE%2C sunA%2C sunT-bdbA-yolJ-bdbB%2C sigO-rsoA%2C and sigX- rsiX)%2C and negatively regulates the lytABC operon%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01767 BL14DL4_01768 BL14DL4_01768 BL14DL4_01768 1609983 1610795 - Iron-chelate-transporting ATPase Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphate importer (TC 3. A. 1. 7) family%3B Contains 1 ABC transporter domain%3B KEGG: eca:ECA1073 iron complex transport system ATP-binding protein gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01768 BL14DL4_01769 BL14DL4_01769 BL14DL4_01769 1610814 1611827 - putative siderophore transport system permease protein YfhA Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen%2C arthrobactin and corprogen%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01769 BL14DL4_01770 BL14DL4_01770 BL14DL4_01770 1611827 1612891 - Achromobactin transport system permease protein CbrB Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01770 BL14DL4_01771 BL14DL4_01771 BL14DL4_01771 1613047 1614450 - Putative arginine/ornithine antiporter Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01771 BL14DL4_01772 BL14DL4_01772 BL14DL4_01772 1615284 1615754 + uncharacterized protein To E. coli YdjM gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01772 BL14DL4_01773 BL14DL4_01773 BL14DL4_01773 1615854 1617713 + Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Belongs to the LTA synthase family%3B KEGG: baci:B1NLA3E_11025 lipoteichoic acid synthase gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01773 BL14DL4_01774 BL14DL4_01774 BL14DL4_01774 1617915 1619366 + Multidrug export protein Part of the tripartite efflux system EmrAB-TolC%2C which confers resistance to antibiotics%3B Belongs to the major facilitator superfamily. EmrB family gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01774 BL14DL4_01775 BL14DL4_01775 dkgA dkgA 1619406 1620245 - 2%2C5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis%3B Belongs to the aldo/keto reductase family%3B KEGG: yfr:AW19_2489 2%2C5-diketo-D-gluconate reductase A gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01775 BL14DL4_01776 BL14DL4_01776 scrK scrK 1620335 1621195 - Fructokinase Seems to be involved in the degradation of glucomannan%3B Belongs to the ROK (NagC/XylR) family%3B KEGG: bli:BL00700 fructokinase gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01776 BL14DL4_01777 BL14DL4_01777 kynU kynU 1621462 1622586 + Kynureninase Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: msv:Mesil_0484 kynureninase gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01777 BL14DL4_01778 BL14DL4_01778 BL14DL4_01778 1622666 1623076 + hypothetical protein gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01778 BL14DL4_01779 BL14DL4_01779 uvrD uvrD 1623082 1625412 - DNA helicase Catalyzes the unwinding of duplex DNA in the 3' to 5' directio%3B this reaction is dependent on the hydrolysis of ATP%3B Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B KEGG: bli:BL00699 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01779 BL14DL4_01780 BL14DL4_01780 BL14DL4_01780 1625591 1626199 - UPF0126 membrane protein YvgT Belongs to the UPF0126 family gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01780 BL14DL4_01781 BL14DL4_01781 BL14DL4_01781 1626324 1626674 + UPF0157 protein Belongs to the UPF0157 (GrpB) family gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01781 BL14DL4_01782 BL14DL4_01782 BL14DL4_01782 1626846 1626938 + hypothetical protein gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01782 BL14DL4_01783 BL14DL4_01783 BL14DL4_01783 1626947 1627432 - hypothetical protein gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01783 BL14DL4_01784 BL14DL4_01784 BL14DL4_01784 1627539 1627952 - Disulfide bond formation protein Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168%2C although it can partially substitute for BdbB when the latter is absent. It may also be required for the stability of other secreted proteins. Not required for sporulation%3B Belongs to the DsbB family. BdbC subfamily gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01784 BL14DL4_01785 BL14DL4_01785 BL14DL4_01785 1627942 1628637 - Disulfide bond formation protein D Required for the stabilization%2C possibly via formation of a disulfide bond%2C of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation%3B Belongs to the thioredoxin family. DsbA subfamily%3B Contains 1 thioredoxin domain gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01785 BL14DL4_01786 BL14DL4_01786 zntA zntA 1628763 1630874 - Cadmium-exporting ATPase Couples the hydrolysis of ATP with the transport of cadmium%2C zinc and cobalt out of the cell. Does not seem to transport copper%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 1 HMA domain%3B KEGG: bli:BL03007 Cd2+/Zn2+-exporting ATPase gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01786 BL14DL4_01787 BL14DL4_01787 BL14DL4_01787 1631127 1632146 + Putative binding protein Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01787 BL14DL4_01788 BL14DL4_01788 BL14DL4_01788 1632368 1633261 + Inner membrane ABC transporter permease protein Probably part of the binding-protein-dependent transport system YcjNOP. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01788 BL14DL4_01789 BL14DL4_01789 BL14DL4_01789 1633258 1634079 + putative ABC transporter permease protein YurM Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01789 BL14DL4_01790 BL14DL4_01790 yicI yicI 1634101 1636410 + Alpha-D-xyloside xylohydrolase Can catalyze the transfer of alpha-xylosyl residue from alpha-xyloside to xylose%2C glucose%2C mannose%2C fructose%2C maltose%2C isomaltose%2C nigerose%2C kojibiose%2C sucrose and trehalose%3B Belongs to the glycosyl hydrolase 31 family%3B KEGG: scu:SCE1572_13305 alpha-D-xyloside xylohydrolase gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01790 BL14DL4_01791 BL14DL4_01791 bglX bglX 1636426 1639371 + Beta-glucosidase A bifunctional beta-xylosidase/alpha-L-arabinosidase%2C exo-enzyme that acts synergistically with endohydrolases. Releases xylose and arabinose from cell walls. Does not cleave xylan from oat spelts although xylan from oat spelts was degraded to xylose when this enzyme was used in combination with xylanase. Also releases xylose and arabinose from aryl glycosides%2C xylo- oligosaccharides%2C arabinan from sugar beet and arabino- oligosaccharides%2C arabinan from sugar beet and arabinoxylan from wheat%3B Belongs to the glycoside hydrolase 3 family%3B KEGG: bli:BL02680 beta-glucosidase gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01791 BL14DL4_01792 BL14DL4_01792 BL14DL4_01792 1639587 1640339 + Octopine permease ATP-binding protein Component of the octopine active transport system probably consisting of four subunits: Q%2C M%2C P and T%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01792 BL14DL4_01793 BL14DL4_01793 BL14DL4_01793 1640339 1641199 + Manganese transport system membrane protein MntC This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the ABC-3 integral membrane protein family gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01793 BL14DL4_01794 BL14DL4_01794 BL14DL4_01794 1641227 1642156 + Zinc-binding protein AdcA Part of the ATP-driven transport system AdcABC for zinc. Belongs to the bacterial solute-binding protein 9 family gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01794 BL14DL4_01795 BL14DL4_01795 BL14DL4_01795 1642261 1642587 + putative cysteine-rich protein YhjQ gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01795 BL14DL4_01796 BL14DL4_01796 BL14DL4_01796 1642697 1643476 + HTH-type transcriptional regulator GlvR Positive regulator of the glv operon expression%2C which consists of GlvA%2C GlvR and GlvC%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01796 BL14DL4_01797 BL14DL4_01797 fruK fruK 1643560 1644474 + 1-phosphofructokinase Belongs to the carbohydrate kinase PfkB family. LacC subfamily%3B KEGG: bli:BL01904 1-phosphofructokinase gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01797 BL14DL4_01798 BL14DL4_01798 BL14DL4_01798 1644488 1645888 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi03550 PTS system%2C fructose-specific IIB component gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01798 BL14DL4_01799 BL14DL4_01799 fruB fruB 1645895 1646353 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi03551 PTS system%2C fructose-specific IIA component gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01799 BL14DL4_01800 BL14DL4_01800 BL14DL4_01800 1646379 1647230 + Tagatose-bisphosphate aldolase Catalytic subunit of the tagatose-1%2C6-bisphosphate aldolase GatYZ%2C which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1%2C6- bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol and D- tagatose%3B Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily%3B KEGG: bli:BL01900 tagatose 1%2C6-diphosphate aldolase GatY/KbaY gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01800 BL14DL4_01801 BL14DL4_01801 BL14DL4_01801 1647275 1647424 - hypothetical protein gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01801 BL14DL4_01802 BL14DL4_01802 copA copA 1647421 1649856 - Cu(+) exporting ATPase Involved in copper export%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B Contains 2 HMA domains%3B KEGG: bli:BL01899 Cu+-exporting ATPase gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01802 BL14DL4_01803 BL14DL4_01803 BL14DL4_01803 1649893 1650102 - Copper chaperone CopZ Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Contains 1 HMA domain gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01803 BL14DL4_01804 BL14DL4_01804 BL14DL4_01804 1650197 1650499 - Copper-sensing transcriptional repressor CsoR Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions%2C binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions%2C CsoR binds Cu(1+)%2C which significantly decreases its DNA binding affinity and leads to the transcription of the genes%3B Belongs to the CsoR family gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01804 BL14DL4_01805 BL14DL4_01805 pfpI pfpI 1650623 1651174 - Protein DJ-1 like protein Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal%2C formed from methylglyoxal and glutathione%2C to S-lactoylglutathione. May be involved in oxidative stress response%3B Belongs to the peptidase C56 family%3B Contains 2 PfpI endopeptidase domains%3B KEGG: bcy:Bcer98_3045 protease I%3B Glycosylases gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01805 BL14DL4_01806 BL14DL4_01806 BL14DL4_01806 1651260 1652021 - putative HTH-type transcriptional regulator YulB Contains 1 HTH deoR-type DNA-binding domain gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01806 BL14DL4_01807 BL14DL4_01807 rhaB rhaB 1652101 1653582 - Rhamnulokinase In the N-terminal sectio%3B belongs to the rhamnulokinase family%3B In the C-terminal sectio%3B belongs to the rhamnose isomerase family%3B KEGG: bli:BL00812 rhamnulokinase gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01807 BL14DL4_01808 BL14DL4_01808 rhaA rhaA 1653579 1654802 - putative sugar isomerase Belongs to the rhamnose isomerase family%3B KEGG: bli:BL00813 L-rhamnose isomerase / sugar isomerase gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01808 BL14DL4_01809 BL14DL4_01809 BL14DL4_01809 1654792 1655181 - hypothetical protein gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01809 BL14DL4_01810 BL14DL4_01810 BL14DL4_01810 1655236 1657305 - putative oxidoreductase YuxG Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bsu:BSU31220 null%3B Oxidoreductases gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01810 BL14DL4_01811 BL14DL4_01811 BL14DL4_01811 1657667 1658866 + putative MFS-type transporter YfhI Belongs to the major facilitator superfamily gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01811 BL14DL4_01812 BL14DL4_01812 BL14DL4_01812 1658884 1660110 - putative MFS-type transporter YvmA Belongs to the major facilitator superfamily. TCR/Tet family gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01812 BL14DL4_01813 BL14DL4_01813 yvmC yvmC 1660647 1661396 + Cyclo(L-leucyl-L-leucyl) synthase Involved in the biosynthesis of pulcherrimin%2C a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues%2C such as L- phenylalanine%2C L-leucine and methionine%2C into cyclodipeptides%3B Belongs to the CDPS family%3B KEGG: bli:BL00817 cyclo(L-leucyl-L-leucyl) synthase gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01813 BL14DL4_01814 BL14DL4_01814 BL14DL4_01814 1661393 1662613 + Pulcherriminic acid synthase Involved in the biosynthesis of pulcherrimin%2C a red extracellular pigment. Catalyzes the oxidation of cyclo(L-Leu-L- Leu) (cLL) to yield pulcherriminic acid which forms pulcherrimin via a nonenzymic reaction with Fe(3+). Substrates with small alkyl groups (cAA%2C cLG%2C cLP) exhibit weaker binding to CYP134A1%2C but substrates with larger hydrophobic side chains bind in a similar regime to cLL%3B Belongs to the cytochrome P450 family%3B KEGG: bli:BL00818 pulcherriminic acid synthase gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01814 BL14DL4_01815 BL14DL4_01815 BL14DL4_01815 1662610 1663065 - hypothetical protein gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01815 BL14DL4_01816 BL14DL4_01816 BL14DL4_01816 1663082 1663555 - putative HTH-type transcriptional regulator YvnA Contains 1 HTH marR-type DNA-binding domain gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01816 BL14DL4_01817 BL14DL4_01817 amiE amiE 1663678 1664856 - Amidase Amidase involved in auxin biosynthesis. Converts indole- 3-acetamide into indole-3-acetic acid. Can also use L-asparagine%2C oleamide and 1-naphtalene-acetamide as substrates%2C but not indole- 3-acetonitrile or indole-3-acetyl-L-aspartic acid%3B Belongs to the amidase family%3B KEGG: blh:BaLi_c36320 amidase gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01817 BL14DL4_01818 BL14DL4_01818 iolW iolW 1665046 1666095 + Scyllo-inositol 2-dehydrogenase (NADP(+)) Catalyzes the NADP(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL00819 scyllo-inositol 2-dehydrogenase (NADP+) gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01818 BL14DL4_01819 BL14DL4_01819 BL14DL4_01819 1666127 1666762 - FMN-dependent NADH-azoreductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH%2C but not NADPH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 1 family%3B KEGG: bli:BL00833 FMN-dependent NADH-azoreductase%3B Acting on other nitrogenous compounds as donors gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01819 BL14DL4_01820 BL14DL4_01820 BL14DL4_01820 1666725 1666904 - hypothetical protein gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01820 BL14DL4_01821 BL14DL4_01821 BL14DL4_01821 1667063 1668031 - UPF0176 protein Belongs to the UPF0176 family%3B Contains 1 rhodanese domain gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01821 BL14DL4_01822 BL14DL4_01822 BL14DL4_01822 1668227 1668445 - Sigma-O factor regulatory protein RsoA Together with RNA polymerase sigma factor SigO%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01822 BL14DL4_01823 BL14DL4_01823 BL14DL4_01823 1668420 1669001 - RNA polymerase sigma factor SigO Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA%2C positively regulates the expression of at least three operons%2C including oxdC-yvrL%2C sigO-rsoA and yvrJ. Required for the acid stress- dependent induction of the oxalate decarboxylase oxdC%3B Belongs to the sigma-70 factor family gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01823 BL14DL4_01824 BL14DL4_01824 BL14DL4_01824 1669158 1669307 + uncharacterized protein gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01824 BL14DL4_01825 BL14DL4_01825 BL14DL4_01825 1669401 1670555 + Oxalate decarboxylase Converts oxalate to formate and CO(2) in an O(2)- dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2)%2C and oxalate-dependent%2C H(2)O(2)-independent dye oxidations%3B To B. subtilis OxdD%3B KEGG: bli:BL00821 oxalate decarboxylase gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01825 BL14DL4_01826 BL14DL4_01826 BL14DL4_01826 1670628 1671026 + Membrane-bound negative regulator YvrL Negatively regulates RNA polymerase sigma factor SigO- dependent transcription. Prevents the expression or secretion of OxdC under nonstress conditions. May act as an anti-sigma factor gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01826 BL14DL4_01827 BL14DL4_01827 BL14DL4_01827 1671123 1671608 + hypothetical protein gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01827 BL14DL4_01828 BL14DL4_01828 BL14DL4_01828 1671761 1671988 + hypothetical protein gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01828 BL14DL4_01829 BL14DL4_01829 BL14DL4_01829 1672390 1672674 + hypothetical protein gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01829 BL14DL4_01830 BL14DL4_01830 BL14DL4_01830 1673497 1674309 + hypothetical protein gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01830 BL14DL4_01831 BL14DL4_01831 BL14DL4_01831 1674533 1674910 - hypothetical protein gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01831 BL14DL4_01832 BL14DL4_01832 BL14DL4_01832 1675034 1675681 - hypothetical protein gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01832 BL14DL4_01833 BL14DL4_01833 BL14DL4_01833 1675931 1676161 - hypothetical protein gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01833 BL14DL4_01834 BL14DL4_01834 BL14DL4_01834 1676416 1676559 - hypothetical protein gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01834 BL14DL4_01835 BL14DL4_01835 BL14DL4_01835 1676752 1678368 + putative ribonuclease YokI Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-571) inhibits growth upon expression in E. coli which is neutralized by cognate antitoxin YokJ%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01835 BL14DL4_01836 BL14DL4_01836 BL14DL4_01836 1678381 1678797 + hypothetical protein gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01836 BL14DL4_01837 BL14DL4_01837 BL14DL4_01837 1678828 1679772 - Lysozyme M1 This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities. Belongs to the glycosyl hydrolase 25 family gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01837 BL14DL4_01838 BL14DL4_01838 BL14DL4_01838 1679820 1680083 - Holin Involved in cell lysis upon induction of PbsX. Belongs to the SPP1 holin family gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01838 BL14DL4_01839 BL14DL4_01839 BL14DL4_01839 1680099 1680368 - putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01839 BL14DL4_01840 BL14DL4_01840 BL14DL4_01840 1680431 1680616 - hypothetical protein gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01840 BL14DL4_01841 BL14DL4_01841 BL14DL4_01841 1680613 1680933 - hypothetical protein gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01841 BL14DL4_01842 BL14DL4_01842 BL14DL4_01842 1680939 1682303 - Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01842 BL14DL4_01843 BL14DL4_01843 BL14DL4_01843 1682324 1684279 - hypothetical protein gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01843 BL14DL4_01844 BL14DL4_01844 BL14DL4_01844 1684315 1686027 - N-acetylmuramoyl-L-alanine amidase Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility%2C chemotaxis and cell division%3B Belongs to the glycosyl hydrolase 73 family%3B KEGG: smu:SMU_76 N-acetylmuramoyl-L-alanine amidase gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01844 BL14DL4_01845 BL14DL4_01845 BL14DL4_01845 1686040 1686876 - hypothetical protein gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01845 BL14DL4_01846 BL14DL4_01846 BL14DL4_01846 1686876 1691345 - Tape measure protein Plays a role in virion tail formation. The length of the tape measure protein is proportional to the length of the phage's tail gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01846 BL14DL4_01847 BL14DL4_01847 BL14DL4_01847 1691408 1691506 - hypothetical protein gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01847 BL14DL4_01848 BL14DL4_01848 BL14DL4_01848 1691554 1691916 - hypothetical protein gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01848 BL14DL4_01849 BL14DL4_01849 BL14DL4_01849 1691970 1692587 - hypothetical protein gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01849 BL14DL4_01850 BL14DL4_01850 BL14DL4_01850 1692602 1692985 - hypothetical protein gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01850 BL14DL4_01851 BL14DL4_01851 BL14DL4_01851 1692982 1693380 - hypothetical protein gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01851 BL14DL4_01852 BL14DL4_01852 BL14DL4_01852 1693380 1693688 - hypothetical protein gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01852 BL14DL4_01853 BL14DL4_01853 BL14DL4_01853 1693678 1693980 - hypothetical protein gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01853 BL14DL4_01854 BL14DL4_01854 BL14DL4_01854 1694001 1694426 - Collagen alpha-1(V) chain Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA%2C heparan sulfate%2C thrombospondin%2C heparin%2C and insulin (By similarity)%3B Belongs to the fibrillar collagen family%3B Contains 1 fibrillar collagen NC1 domain%3B Contains 1 laminin G-like domain gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01854 BL14DL4_01855 BL14DL4_01855 BL14DL4_01855 1694450 1695733 - hypothetical protein gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01855 BL14DL4_01856 BL14DL4_01856 clpP clpP 1695772 1696503 - Endopeptidase Clp KEGG: cba:CLB_2447 ATP-dependent Clp protease%2C protease subunit gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01856 BL14DL4_01857 BL14DL4_01857 BL14DL4_01857 1696448 1697758 - hypothetical protein gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01857 BL14DL4_01858 BL14DL4_01858 BL14DL4_01858 1697759 1697950 - hypothetical protein gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01858 BL14DL4_01859 BL14DL4_01859 BL14DL4_01859 1697962 1699671 - Putative terminase large subunit Belongs to the phage terminase family gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01859 BL14DL4_01860 BL14DL4_01860 BL14DL4_01860 1699668 1700183 - hypothetical protein gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01860 BL14DL4_01861 BL14DL4_01861 BL14DL4_01861 1700413 1700787 - hypothetical protein gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01861 BL14DL4_01862 BL14DL4_01862 BL14DL4_01862 1700814 1701122 - hypothetical protein gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01862 BL14DL4_01863 BL14DL4_01863 BL14DL4_01863 1701296 1701637 - hypothetical protein gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01863 BL14DL4_01864 BL14DL4_01864 BL14DL4_01864 1701722 1702345 - hypothetical protein gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01864 BL14DL4_01865 BL14DL4_01865 BL14DL4_01865 1702590 1702814 - Spore coat protein gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01865 BL14DL4_01866 BL14DL4_01866 BL14DL4_01866 1703565 1703945 - hypothetical protein gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01866 BL14DL4_01867 BL14DL4_01867 BL14DL4_01867 1703963 1704061 - hypothetical protein gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01867 BL14DL4_01868 BL14DL4_01868 BL14DL4_01868 1704058 1704435 - hypothetical protein gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01868 BL14DL4_01869 BL14DL4_01869 BL14DL4_01869 1704451 1704972 - hypothetical protein gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01869 BL14DL4_01870 BL14DL4_01870 BL14DL4_01870 1704969 1705139 - hypothetical protein gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01870 BL14DL4_01871 BL14DL4_01871 BL14DL4_01871 1705136 1705675 - hypothetical protein gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01871 BL14DL4_01872 BL14DL4_01872 BL14DL4_01872 1705672 1706109 - hypothetical protein gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01872 BL14DL4_01873 BL14DL4_01873 BL14DL4_01873 1706087 1706350 - hypothetical protein gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01873 BL14DL4_01874 BL14DL4_01874 BL14DL4_01874 1706626 1709058 - Putative helicase L207/L206 Contains 1 SF3 helicase domain gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01874 BL14DL4_01875 BL14DL4_01875 BL14DL4_01875 1709119 1709556 - hypothetical protein gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01875 BL14DL4_01876 BL14DL4_01876 BL14DL4_01876 1709556 1710488 - hypothetical protein gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01876 BL14DL4_01877 BL14DL4_01877 BL14DL4_01877 1710492 1711049 - hypothetical protein gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01877 BL14DL4_01878 BL14DL4_01878 BL14DL4_01878 1711142 1711384 - hypothetical protein gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01878 BL14DL4_01879 BL14DL4_01879 BL14DL4_01879 1711365 1711475 - hypothetical protein gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01879 BL14DL4_01880 BL14DL4_01880 BL14DL4_01880 1711472 1711738 - hypothetical protein gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01880 BL14DL4_01881 BL14DL4_01881 BL14DL4_01881 1711801 1712130 + hypothetical protein gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01881 BL14DL4_01882 BL14DL4_01882 BL14DL4_01882 1712127 1712285 - hypothetical protein gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01882 BL14DL4_01883 BL14DL4_01883 BL14DL4_01883 1712307 1712396 - hypothetical protein gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01883 BL14DL4_01884 BL14DL4_01884 BL14DL4_01884 1712411 1712965 - hypothetical protein gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01884 BL14DL4_01885 BL14DL4_01885 BL14DL4_01885 1713023 1713211 - hypothetical protein gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01885 BL14DL4_01886 BL14DL4_01886 BL14DL4_01886 1713528 1714322 - hypothetical protein gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01886 BL14DL4_01887 BL14DL4_01887 BL14DL4_01887 1714431 1714664 - hypothetical protein gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01887 BL14DL4_01888 BL14DL4_01888 BL14DL4_01888 1714830 1715525 + hypothetical protein gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01888 BL14DL4_01889 BL14DL4_01889 BL14DL4_01889 1715596 1716690 + ICEBs1 integrase Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome%2C attB%2C and a site in the circular form of ICEBs1%2C attICEBs1%3B Belongs to the 'phage' integrase family gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01889 BL14DL4_01890 BL14DL4_01890 BL14DL4_01890 1717242 1717715 - SsrA-binding protein Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA)%2C required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape%2C replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gen%3B the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide'%2C a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA%2C entering the A-site of stalled ribosomes%2C displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRN%3B the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation%2C which seems to be the essential function of trans- translation%3B Belongs to the SmpB family gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01890 BL14DL4_01891 BL14DL4_01891 vacB vacB 1717827 1720130 - Ribonuclease 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs%3B Belongs to the RNR ribonuclease family. RNase R subfamily%3B Contains 1 S1 motif domain%3B KEGG: bli:BL03482 ribonuclease R%3B Acting on ester bonds gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01891 BL14DL4_01892 BL14DL4_01892 yvaK yvaK 1720144 1720890 - Carboxylesterase Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates%2C with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones (By similarity)%3B Belongs to the lipase/esterase LIP3/BchO family%3B KEGG: bli:BL03481 carboxylesterase gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01892 BL14DL4_01893 BL14DL4_01893 BL14DL4_01893 1721031 1721261 - putative protein-export membrane protein SecG Involved in protein export. Participates in an early event of protein translocation (By similarity)%3B Belongs to the SecG family gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01893 BL14DL4_01894 BL14DL4_01894 BL14DL4_01894 1721432 1721716 - Transition state regulatory protein AbrB Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01894 BL14DL4_01895 BL14DL4_01895 BL14DL4_01895 1721745 1722062 - putative HTH-type transcriptional regulator YvzC Contains 1 HTH cro/C1-type DNA-binding domain gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01895 BL14DL4_01896 BL14DL4_01896 BL14DL4_01896 1722131 1722532 + HTH-type transcriptional repressor RghR Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM%2C rapG and rapH%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01896 BL14DL4_01897 BL14DL4_01897 BL14DL4_01897 1722702 1723100 + Repressor LexA Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: aac:Aaci_2954 repressor LexA gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01897 BL14DL4_01898 BL14DL4_01898 BL14DL4_01898 1723148 1723825 - Choline transport system permease protein OpuBD Involved in a high affinity multicomponent binding- protein-dependent transport system for cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01898 BL14DL4_01899 BL14DL4_01899 BL14DL4_01899 1723842 1724759 - Glycine betaine/carnitine/choline-binding protein OpuCC Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine%2C and choline%3B Belongs to the OsmX family gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01899 BL14DL4_01900 BL14DL4_01900 BL14DL4_01900 1724773 1725426 - Glycine betaine/carnitine/choline transport system permease protein OpuCB Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine%2C carnitine and cholin%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01900 BL14DL4_01901 BL14DL4_01901 BL14DL4_01901 1725448 1726587 - Energy-coupling factor transporter ATP-binding protein EcfA ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01901 BL14DL4_01902 BL14DL4_01902 BL14DL4_01902 1726845 1727384 + HTH-type transcriptional repressor OpcR Negatively regulates the transcription of the opuC operon. In the absence of GbsR%2C is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons%3B Belongs to the GbsR family gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01902 BL14DL4_01903 BL14DL4_01903 BL14DL4_01903 1727431 1728063 - UPF0056 membrane protein YvbG Belongs to the UPF0056 (MarC) family gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01903 BL14DL4_01904 BL14DL4_01904 BL14DL4_01904 1728425 1729003 + uncharacterized protein gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01904 BL14DL4_01905 BL14DL4_01905 BL14DL4_01905 1729047 1730174 - putative membrane protein YvbJ gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01905 BL14DL4_01906 BL14DL4_01906 BL14DL4_01906 1730149 1730814 - putative membrane protein YvbJ gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01906 BL14DL4_01907 BL14DL4_01907 BL14DL4_01907 1730887 1731891 - Fe(3+)-citrate-binding protein YfmC Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of YfmDE (Probable)%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01907 BL14DL4_01908 BL14DL4_01908 BL14DL4_01908 1732180 1732572 + hypothetical protein gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01908 BL14DL4_01909 BL14DL4_01909 BL14DL4_01909 1733175 1733807 - putative protease YoaZ Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01909 BL14DL4_01910 BL14DL4_01910 BL14DL4_01910 1733943 1735235 - Phosphopyruvate hydratase Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis%3B Belongs to the enolase family%3B KEGG: bsu:BSU33900 enolase gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01910 BL14DL4_01911 BL14DL4_01911 gpmI gpmI 1735258 1736793 - Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate%3B Belongs to the BPG-independent phosphoglycerate mutase family%3B KEGG: bli:BL03467 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01911 BL14DL4_01912 BL14DL4_01912 tpiA tpiA 1736786 1737547 - Triose-phosphate isomerase Belongs to the triosephosphate isomerase family%3B KEGG: mej:Q7A_2894 triosephosphate isomerase (TIM) gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01912 BL14DL4_01913 BL14DL4_01913 BL14DL4_01913 1737578 1738762 - Phosphoglycerate kinase Belongs to the phosphoglycerate kinase family%3B KEGG: sat:SYN_01396 phosphoglycerate kinase gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01913 BL14DL4_01914 BL14DL4_01914 BL14DL4_01914 1738936 1739943 - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1%2C3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue%2C and this hemiacetal intermediate is then oxidized to a thioester%2C with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD%2C and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG%3B Belongs to the glyceraldehyde-3-phosphate dehydrogenase family%3B KEGG: eco:b1779 glyceraldehyde 3-phosphate dehydrogenase gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01914 BL14DL4_01915 BL14DL4_01915 BL14DL4_01915 1739977 1741017 - Central glycolytic protein regulator In the absence of glucose%2C represses the transcription of the gapA operon%2C which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase%2C leading to the arrest of the transcription%3B Belongs to the SorC transcriptional regulatory family gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01915 BL14DL4_01916 BL14DL4_01916 BL14DL4_01916 1741419 1742426 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01916 BL14DL4_01917 BL14DL4_01917 BL14DL4_01917 1742566 1743921 - Amino-acid permease RocC Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01917 BL14DL4_01918 BL14DL4_01918 BL14DL4_01918 1744565 1745038 + hypothetical protein gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01918 BL14DL4_01919 BL14DL4_01919 BL14DL4_01919 1745215 1746141 - Galactose/methyl galactoside import ATP-binding protein MglA Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01919 BL14DL4_01920 BL14DL4_01920 BL14DL4_01920 1746141 1746830 - hypothetical protein gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01920 BL14DL4_01921 BL14DL4_01921 BL14DL4_01921 1747164 1747886 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutC/YkgG family gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01921 BL14DL4_01922 BL14DL4_01922 BL14DL4_01922 1747883 1749316 - Lactate utilization protein Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate%3B Belongs to the LutB/YkgF family%3B Contains 2 4Fe-4S ferredoxin-type domains gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01922 BL14DL4_01923 BL14DL4_01923 BL14DL4_01923 1749360 1750145 - Lactate utilization protein A Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source%3B Belongs to the LutA/YkgE family gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01923 BL14DL4_01924 BL14DL4_01924 BL14DL4_01924 1750219 1750959 - Exu regulon transcriptional regulator Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT%2C UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers. Contains 1 HTH gntR-type DNA-binding domain gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01924 BL14DL4_01925 BL14DL4_01925 BL14DL4_01925 1751167 1752858 + L-lactate permease Is the principal permease for the uptake of L-lactate in B. subtilis%3B Belongs to the lactate permease family gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01925 BL14DL4_01926 BL14DL4_01926 BL14DL4_01926 1752892 1754205 - RNA polymerase sigma-54 factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the levanase operon. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein LevR for the expression of the levanase operon. Belongs to the sigma-54 factor family gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01926 BL14DL4_01927 BL14DL4_01927 BL14DL4_01927 1754276 1754491 + uncharacterized protein gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01927 BL14DL4_01928 BL14DL4_01928 epsO epsO 1754507 1755484 - Putative pyruvyl transferase EpsO May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bli:BL03453 pyruvyl transferase EpsO%3B Transferases gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01928 BL14DL4_01929 BL14DL4_01929 epsN epsN 1755495 1756640 - Putative pyridoxal phosphate-dependent aminotransferase EpsN May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bli:BL03452 pyridoxal phosphate-dependent aminotransferase EpsN%3B Transaminases gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01929 BL14DL4_01930 BL14DL4_01930 epsM epsM 1756664 1757290 - Putative acetyltransferase EpsM May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the transferase hexapeptide repeat family%3B KEGG: bli:BL03451 acetyltransferase EpsM%3B Transferring groups other than amino-acyl groups gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01930 BL14DL4_01931 BL14DL4_01931 BL14DL4_01931 1757290 1757892 - Undecaprenyl-phosphate glucose phosphotransferase Involved in the biosynthesis of the exopolysaccharide acetan%2C a water-soluble polysaccharide involved in production of bacterial cellulose (BC)%3B Belongs to the bacterial sugar transferase family gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01931 BL14DL4_01932 BL14DL4_01932 BL14DL4_01932 1757913 1759469 - putative membrane protein EpsK gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01932 BL14DL4_01933 BL14DL4_01933 epsJ epsJ 1759466 1760485 - Chondroitin synthase Catalyzes the polymerization of chondroitin%2C a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc. Belongs to the glycosyltransferase 2 family. CS/HAS subfamily%3B KEGG: bli:BL03447 glycosyltransferase EpsJ%3B Glycosyltransferases gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01933 BL14DL4_01934 BL14DL4_01934 epsI epsI 1760482 1761561 - Putative pyruvyl transferase EpsI May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Belongs to the polysaccharide pyruvyl transferase family%3B KEGG: bli:BL03446 pyruvyl transferase EpsI%3B Transferases gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01934 BL14DL4_01935 BL14DL4_01935 epsH epsH 1761573 1762604 - Putative glycosyltransferase EpsH May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance%3B Belongs to the glycosyltransferase 2 family%3B KEGG: bli:BL03445 glycosyltransferase EpsH%3B Glycosyltransferases gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01935 BL14DL4_01936 BL14DL4_01936 BL14DL4_01936 1762664 1763767 - Transmembrane protein EpsG gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01936 BL14DL4_01937 BL14DL4_01937 epsF epsF 1763772 1764932 - Putative glycosyltransferase EpsF May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bli:BL03443 glycosyltransferase EpsF%3B Glycosyltransferases gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01937 BL14DL4_01938 BL14DL4_01938 epsE epsE 1764925 1765767 - Putative glycosyltransferase EpsE May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase 2 family%3B KEGG: bli:BL03442 glycosyltransferase EpsE%3B Glycosyltransferases gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01938 BL14DL4_01939 BL14DL4_01939 epsD epsD 1765764 1766912 - Putative glycosyltransferase EpsD May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bli:BL03441 glycosyltransferase EpsD%3B Glycosyltransferases gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01939 BL14DL4_01940 BL14DL4_01940 BL14DL4_01940 1766923 1768740 - putative polysaccharide biosynthesis protein EpsC Involved in biofilm formation%3B Belongs to the polysaccharide synthase family gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01940 BL14DL4_01941 BL14DL4_01941 epsB epsB 1769001 1769693 - Non-specific protein-tyrosine kinase Belongs to the CpsD/CapB family%3B KEGG: bli:BL03438 protein-tyrosine kinase gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01941 BL14DL4_01942 BL14DL4_01942 BL14DL4_01942 1769683 1770435 - uncharacterized protein Belongs to the CpsC/CapA family gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01942 BL14DL4_01943 BL14DL4_01943 BL14DL4_01943 1770671 1771129 + HTH-type transcriptional regulator SlrR Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B Contains 1 Sin domain gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01943 BL14DL4_01944 BL14DL4_01944 BL14DL4_01944 1771131 1771277 - hypothetical protein gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01944 BL14DL4_01945 BL14DL4_01945 BL14DL4_01945 1771539 1772063 + General stress protein Belongs to the NAD(P)H dehydrogenase (quinone) family gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01945 BL14DL4_01946 BL14DL4_01946 BL14DL4_01946 1772100 1773383 - putative glucarate transporter Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01946 BL14DL4_01947 BL14DL4_01947 BL14DL4_01947 1773453 1774403 - Phosphoglycerate dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B Contains 1 ACT domain%3B KEGG: kpu:KP1_2666 D-3-phosphoglycerate dehydrogenase gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01947 BL14DL4_01948 BL14DL4_01948 BL14DL4_01948 1774431 1775429 - 4-hydroxythreonine-4-phosphate dehydrogenase Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)%3B Belongs to the PdxA family%3B KEGG: bli:BL03434 4-hydroxythreonine-4-phosphate dehydrogenase gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01948 BL14DL4_01949 BL14DL4_01949 BL14DL4_01949 1775433 1776704 - uncharacterized protein To E. coli YgbK gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01949 BL14DL4_01950 BL14DL4_01950 adhE adhE 1776718 1777884 - Acetaldehyde dehydrogenase (acetylating) Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and can not use NADP%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: hor:Hore_02110 acetaldehyde dehydrogenase / alcohol dehydrogenase gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01950 BL14DL4_01951 BL14DL4_01951 BL14DL4_01951 1777898 1778785 - 4-hydroxy-tetrahydrodipicolinate synthase Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bli:BL03431 4-hydroxy-tetrahydrodipicolinate synthase gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01951 BL14DL4_01952 BL14DL4_01952 BL14DL4_01952 1778929 1780647 - Propionate catabolism operon regulatory protein Involved in the transcriptional regulation of the propionate catabolism operon. Contains 1 sigma-54 factor interaction domain gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01952 BL14DL4_01953 BL14DL4_01953 BL14DL4_01953 1780747 1781070 - putative HTH-type transcriptional regulator Contains 1 HTH hxlR-type DNA-binding domain gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01953 BL14DL4_01954 BL14DL4_01954 fadH fadH 1781242 1782336 + 2%2C4-dienoyl-CoA reductase (NADPH) Belongs to the NADH:flavin oxidoreductase/NADH oxidase family%3B KEGG: bur:Bcep18194_C7286 2%2C4-dienoyl-CoA reductase (NADPH2) gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01954 BL14DL4_01955 BL14DL4_01955 sacB sacB 1782686 1784134 + Levansucrase Belongs to the glycosyl hydrolase 68 family%3B KEGG: blh:BaLi_c37120 levansucrase gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01955 BL14DL4_01956 BL14DL4_01956 levB levB 1784211 1785758 + 2%2C6-beta-fructan 6-levanbiohydrolase Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL03606 levanbiose-producing levanase gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01956 BL14DL4_01957 BL14DL4_01957 BL14DL4_01957 1785884 1785959 - tRNA-Arg tRNA gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01957 BL14DL4_01958 BL14DL4_01958 BL14DL4_01958 1786056 1786373 - hypothetical protein gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01958 BL14DL4_01959 BL14DL4_01959 BL14DL4_01959 1786614 1787210 + Endopeptidase Clp Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: eco:b0437 ATP-dependent Clp protease%2C protease subunit gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01959 BL14DL4_01960 BL14DL4_01960 BL14DL4_01960 1787290 1787865 - putative cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG6 Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (By similarity)%3B Belongs to the LOG family gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01960 BL14DL4_01961 BL14DL4_01961 BL14DL4_01961 1787977 1788312 + uncharacterized protein gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01961 BL14DL4_01962 BL14DL4_01962 BL14DL4_01962 1788299 1789276 + uncharacterized protein Contains 1 HD domain gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01962 BL14DL4_01963 BL14DL4_01963 BL14DL4_01963 1789323 1790942 - Putative sulfate transporter YvdB Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01963 BL14DL4_01964 BL14DL4_01964 BL14DL4_01964 1790964 1791554 - Carbonate dehydratase Reversible hydration of carbon dioxide%3B Belongs to the beta-class carbonic anhydrase family%3B KEGG: bli:BL03424 carbonic anhydrase gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01964 BL14DL4_01965 BL14DL4_01965 BL14DL4_01965 1791951 1792922 + Gluconate 2-dehydrogenase Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family%3B KEGG: bsu:BSU34680 gluconate 2-dehydrogenase gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01965 BL14DL4_01966 BL14DL4_01966 BL14DL4_01966 1792933 1793532 - uncharacterized protein Belongs to the flavoredoxin family gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01966 BL14DL4_01967 BL14DL4_01967 BL14DL4_01967 1793621 1794316 + putative HTH-type transcriptional regulator YdfF Contains 1 HTH arsR-type DNA-binding domain gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01967 BL14DL4_01968 BL14DL4_01968 BL14DL4_01968 1794574 1795029 + Ribonuclease Hydrolyzes phosphodiester bonds in RNA%2C poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2'%2C3'-cyclophosphate intermediates. Belongs to the ribonuclease N1/T1 family gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01968 BL14DL4_01969 BL14DL4_01969 BL14DL4_01969 1795034 1795309 + Barstar Inhibitor of the ribonuclease barnase. Forms a one-to- one non-covalent complex. Belongs to the barstar family gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01969 BL14DL4_01970 BL14DL4_01970 nhoA nhoA 1795377 1796135 - N-hydroxyarylamine O-acetyltransferase Belongs to the arylamine N-acetyltransferase family%3B KEGG: blh:BaLi_c37260 N-hydroxyarylamine O-acetyltransferase gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01970 BL14DL4_01971 BL14DL4_01971 BL14DL4_01971 1796178 1796447 - HPr-like protein Crh Along with seryl-phosphorylated HPr%2C phosphorylated Crh is implicated in carbon catabolite repression (CCR) of levanase%2C inositol dehydrogenase%2C and beta-xylosidase. Exerts its effect on CCR by interacting with CcpA%3B Belongs to the HPr family%3B Contains 1 HPr domain gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01971 BL14DL4_01972 BL14DL4_01972 BL14DL4_01972 1796465 1797415 - Putative sporulation transcription regulator WhiA May be required for sporulation%3B Belongs to the WhiA transcriptional regulatory family gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01972 BL14DL4_01973 BL14DL4_01973 BL14DL4_01973 1797444 1798439 - Gluconeoproteinis factor Required for morphogenesis under gluconeogenic growth conditions. Required%2C in gluconeogenic growth conditions%2C for the correct localization of PBP1 and hence for displaying a normal rod shape%3B Belongs to the gluconeogenesis factor family gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01973 BL14DL4_01974 BL14DL4_01974 BL14DL4_01974 1798399 1799286 - Nucleotide-binding protein Displays ATPase and GTPase activities%3B Belongs to the RapZ-like family gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01974 BL14DL4_01975 BL14DL4_01975 BL14DL4_01975 1799308 1799772 - 8-oxo-dGTP diphosphatase Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bsu:BSU34780 8-oxo-dGTP diphosphatase gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01975 BL14DL4_01976 BL14DL4_01976 BL14DL4_01976 1800193 1801143 - Thioredoxin-disulfide reductase Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: rsl:RPSI07_mp0554 thioredoxin reductase (NADPH) gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01976 BL14DL4_01977 BL14DL4_01977 BL14DL4_01977 1801310 1802770 - TPR repeat-containing protein YvcD Contains 3 TPR repeats gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01977 BL14DL4_01978 BL14DL4_01978 BL14DL4_01978 1803065 1803544 + putative N-acetyltransferase YbbJ Contains 1 N-acetyltransferase domain gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01978 BL14DL4_01979 BL14DL4_01979 BL14DL4_01979 1803603 1804235 - Phosphoribosyl-ATP diphosphatase Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP%3B Belongs to the PRA-CH family%3B KEGG: bli:BL03413 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01979 BL14DL4_01980 BL14DL4_01980 hisF hisF 1804232 1804990 - Imidazole glycerol phosphate synthase subunit HisF IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit%3B Belongs to the HisA/HisF family%3B KEGG: xfa:XF2214 cyclase%3B Oxo-acid-lyases gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01980 BL14DL4_01981 BL14DL4_01981 hisA hisA 1804987 1805724 - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamideisomerase Belongs to the HisA/HisF family%3B KEGG: bli:BL03411 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01981 BL14DL4_01982 BL14DL4_01982 hisH hisH 1805721 1806359 - Imidazole glycerol phosphate synthase subunit HisH IGPS catalyzes the conversion of PRFAR and glutamine to IGP%2C AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: cff:CFF8240_1352 glutamine amidotransferase%3B Pentosyltransferases gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01982 BL14DL4_01983 BL14DL4_01983 hisB hisB 1806360 1806944 - Imidazoleglycerol-phosphate dehydratase Belongs to the imidazoleglycerol-phosphate dehydratase family%3B KEGG: hba:Hbal_3133 imidazoleglycerol-phosphate dehydratase gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01983 BL14DL4_01984 BL14DL4_01984 hisD hisD 1806944 1808224 - Histidinol dehydrogenase Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine%3B Belongs to the histidinol dehydrogenase family%3B KEGG: bsu:BSU34910 histidinol dehydrogenase gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01984 BL14DL4_01985 BL14DL4_01985 hisG hisG 1808221 1808862 - ATP phosphoribosyltransferase Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity%3B Belongs to the ATP phosphoribosyltransferase family. Short subfamily%3B KEGG: csa:Csal_2213 ATP phosphoribosyltransferase gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01985 BL14DL4_01986 BL14DL4_01986 BL14DL4_01986 1808855 1810030 - ATP phosphoribosyltransferase regulatory subunit Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine%3B Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01986 BL14DL4_01987 BL14DL4_01987 BL14DL4_01987 1810266 1811000 + uncharacterized protein gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01987 BL14DL4_01988 BL14DL4_01988 pelC pelC 1811284 1811949 + Pectate lyase Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%25%2C with an endo mode of action. In contrast to the majority of pectate lyases%2C displays high activity on highly methylated pectins (By similarity)%3B Belongs to the polysaccharide lyase 3 family%3B KEGG: bli:BL03597 pectate lyase C gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01988 BL14DL4_01989 BL14DL4_01989 lacA lacA 1811979 1812497 - Galactoside O-acetyltransferase Belongs to the transferase hexapeptide repeat family%3B KEGG: nph:NP_4198A galactoside O-acetyltransferase gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01989 BL14DL4_01990 BL14DL4_01990 ppaX ppaX 1812494 1813141 - Inorganic diphosphatase Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool%3B Belongs to the HAD-like hydrolase superfamily. PpaX family%3B KEGG: bli:BL03404 pyrophosphatase PpaX gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01990 BL14DL4_01991 BL14DL4_01991 BL14DL4_01991 1813131 1814078 - putative membrane protein YvoD gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01991 BL14DL4_01992 BL14DL4_01992 umpA umpA 1814104 1814916 - Prolipoprotein diacylglyceryl transferase Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins%3B Belongs to the Lgt family%3B KEGG: bli:BL03402 phosphatidylglycerol:prolipoprotein diacylglycerol transferase%3B Transferases gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01992 BL14DL4_01993 BL14DL4_01993 hprK hprK 1814928 1815860 - HPr kinase/phosphorylase Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr%2C a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing%2C inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites%2C which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose%2C fructose%2C etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore%2C by controlling the phosphorylation state of HPr and crh%2C HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR)%2C and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion%3B Belongs to the HPrK/P family%3B KEGG: bsu:BSU35000 HPr kinase/phosphorylase%3B Protein-serine/threonine kinases gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01993 BL14DL4_01994 BL14DL4_01994 BL14DL4_01994 1816043 1816522 + putative HTH-type transcriptional regulator YfiV Contains 1 HTH marR-type DNA-binding domain gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01994 BL14DL4_01995 BL14DL4_01995 BL14DL4_01995 1816662 1818221 + putative MFS-type transporter YfiU Belongs to the major facilitator superfamily. TCR/Tet family gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01995 BL14DL4_01996 BL14DL4_01996 BL14DL4_01996 1818239 1822228 - uncharacterized protein gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01996 BL14DL4_01997 BL14DL4_01997 BL14DL4_01997 1822326 1822685 - putative membrane protein YvlD gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01997 BL14DL4_01998 BL14DL4_01998 BL14DL4_01998 1822682 1822882 - putative membrane protein YvlC gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01998 BL14DL4_01999 BL14DL4_01999 BL14DL4_01999 1822887 1823981 - uncharacterized protein gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_01999 BL14DL4_02000 BL14DL4_02000 BL14DL4_02000 1824007 1824333 - uncharacterized protein gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02000 BL14DL4_02001 BL14DL4_02001 BL14DL4_02001 1824548 1824778 + uncharacterized protein gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02001 BL14DL4_02002 BL14DL4_02002 BL14DL4_02002 1825011 1825154 - Virulence protein Is critically involved in promoting the replication of S. typhimurium cells inside host macrophages%2C suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidoglycan layer of the cell wall gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02002 BL14DL4_02003 BL14DL4_02003 BL14DL4_02003 1825298 1828171 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB%2C the UvrA molecules dissociate%3B Belongs to the ABC transporter superfamily. UvrA family%3B Contains 2 ABC transporter domains gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02003 BL14DL4_02004 BL14DL4_02004 BL14DL4_02004 1828179 1830164 - UvrABC system protein The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site%2C the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix%2C facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found%2C the DNA wraps around the other UvrB subunit that will check the other stand for damage%3B Belongs to the UvrB family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B Contains 1 UVR domain gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02004 BL14DL4_02005 BL14DL4_02005 BL14DL4_02005 1830348 1830581 - Protein CsbA gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02005 BL14DL4_02006 BL14DL4_02006 BL14DL4_02006 1830700 1830993 - hypothetical protein gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02006 BL14DL4_02007 BL14DL4_02007 BL14DL4_02007 1831118 1832353 - Cell division topological determinant MinJ The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division%2C thereby ensuring that division occurs only once per cell cycle. MinJ acts as a bridge between DivIVA and MinD. May modulate activity and localization of MinD and MinC through direct interaction with MinD%3B Belongs to the MinJ family%3B Contains 1 PDZ (DHR) domain gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02007 BL14DL4_02008 BL14DL4_02008 BL14DL4_02008 1832627 1832980 - Swarming motility protein SwrAA Required for swarm cell differentiation. Plays a crucial role in regulating the degree of cell flagellation gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02008 BL14DL4_02009 BL14DL4_02009 BL14DL4_02009 1833333 1834772 - C-terminal processing peptidase Belongs to the peptidase S41A family%3B Contains 1 PDZ (DHR) domain%3B KEGG: bli:BL03390 carboxyl-terminal processing protease gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02009 BL14DL4_02010 BL14DL4_02010 ttuC ttuC 1834902 1836011 - Tartrate dehydrogenase Belongs to the isocitrate and isopropylmalate dehydrogenases family%3B KEGG: bli:BL03389 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02010 BL14DL4_02011 BL14DL4_02011 BL14DL4_02011 1836116 1837366 - Golgin IMH1 Involved in vesicular transport between an endosomal compartment and the Golgi apparatus%3B Contains 1 GRIP domain gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02011 BL14DL4_02012 BL14DL4_02012 BL14DL4_02012 1837459 1838358 - Cell division protein FtsX Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC-4 integral membrane protein family. FtsX subfamily gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02012 BL14DL4_02013 BL14DL4_02013 BL14DL4_02013 1838342 1839028 - Cell division ATP-binding protein FtsE Part of the ABC transporter FtsEX involved in sporulation. May act as an importer%2C possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA%2C KinB and KinC%2C the RapA phosphatase and the Spo0A sporulation protein%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02013 BL14DL4_02014 BL14DL4_02014 BL14DL4_02014 1839381 1839707 - Cytochrome c-551 Electron carrier protein%3B Contains 1 cytochrome c domain gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02014 BL14DL4_02015 BL14DL4_02015 BL14DL4_02015 1839756 1840610 - UPF0750 membrane protein YvjA Belongs to the UPF0750 family gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02015 BL14DL4_02016 BL14DL4_02016 BL14DL4_02016 1840811 1841794 - Peptide chain release factor Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. Belongs to the prokaryotic/mitochondrial release factor family gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02016 BL14DL4_02017 BL14DL4_02017 BL14DL4_02017 1841975 1844500 - Protein translocase subunit SecA Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane%2C serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane%3B Belongs to the SecA family gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02017 BL14DL4_02018 BL14DL4_02018 BL14DL4_02018 1844661 1845221 - uncharacterized protein Belongs to the ribosomal protein S30Ae family gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02018 BL14DL4_02019 BL14DL4_02019 BL14DL4_02019 1845448 1845825 - uncharacterized protein gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02019 BL14DL4_02020 BL14DL4_02020 BL14DL4_02020 1845835 1846176 - Flagellar protein FliT May act as an export chaperone for the filament capping protein FliD%3B Belongs to the bacillales FliT family gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02020 BL14DL4_02021 BL14DL4_02021 BL14DL4_02021 1846176 1846577 - Flagellar protein FliS Belongs to the FliS family gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02021 BL14DL4_02022 BL14DL4_02022 BL14DL4_02022 1846599 1848080 - Flagellar hook-associated protein Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure%2C which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity)%3B Belongs to the FliD family gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02022 BL14DL4_02023 BL14DL4_02023 BL14DL4_02023 1848099 1848440 - uncharacterized protein gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02023 BL14DL4_02024 BL14DL4_02024 BL14DL4_02024 1848625 1849446 - Flagellin Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Belongs to the bacterial flagellin family gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02024 BL14DL4_02025 BL14DL4_02025 BL14DL4_02025 1849580 1849804 - Carbon storage regulator like protein Could accelerate the degradation of some genes transcripts potentially through selective RNA binding%3B Belongs to the CsrA family gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02025 BL14DL4_02026 BL14DL4_02026 BL14DL4_02026 1849798 1850232 - Flagellar assembly factor FliW Binds to the C-terminal region of flagellin%2C which is implicated in polymerization%2C and participates in the assembly of the flagellum%3B Belongs to the FliW family gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02026 BL14DL4_02027 BL14DL4_02027 BL14DL4_02027 1850251 1850817 - uncharacterized protein gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02027 BL14DL4_02028 BL14DL4_02028 BL14DL4_02028 1850867 1851778 - Flagellar hook-associated protein Belongs to the bacterial flagellin family gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02028 BL14DL4_02029 BL14DL4_02029 BL14DL4_02029 1851789 1853312 - Flagellar hook-associated protein Belongs to the flagella basal body rod proteins family gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02029 BL14DL4_02030 BL14DL4_02030 BL14DL4_02030 1853328 1853804 - uncharacterized protein gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02030 BL14DL4_02031 BL14DL4_02031 BL14DL4_02031 1853823 1854089 - Negative regulator of flagellin synthesis Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor- dependent transcription. Belongs to the FlgM family gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02031 BL14DL4_02032 BL14DL4_02032 BL14DL4_02032 1854169 1854588 - uncharacterized protein May be involved in the assembly%2C structure%2C or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum. To S. typhimurium FliF gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02032 BL14DL4_02033 BL14DL4_02033 BL14DL4_02033 1855338 1855622 - ComF operon protein gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02033 BL14DL4_02034 BL14DL4_02034 BL14DL4_02034 1855677 1857071 - ComF operon protein Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel. Belongs to the helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02034 BL14DL4_02035 BL14DL4_02035 BL14DL4_02035 1857192 1858034 - DegV domain-containing protein May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02035 BL14DL4_02036 BL14DL4_02036 BL14DL4_02036 1858154 1858843 - Transcriptional regulatory protein DegU Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation%2C biofilm formation%2C and competence for DNA uptake. Positively or negatively regulates expression of many different genes. The phosphorylated form is required for synthesis of degradative enzymes%2C flagellum formation and biofilm formation. The unphosphorylated form is required for expression of genetic competence%2C via induction of comK%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02036 BL14DL4_02037 BL14DL4_02037 degS degS 1858925 1860082 - Histidine kinase Member of the two-component regulatory system DegS/DegU%2C which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions%2C including production of degradative enzymes such as the neutral and alkaline proteases%2C flagellum formation and biofilm formation. Acts as both a protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to DegU%2C and a protein phosphatase that dephosphorylates phospho- DegU%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03360 two-component system%2C NarL family%2C sensor histidine kinase DegS gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02037 BL14DL4_02038 BL14DL4_02038 pepQ pepQ 1860296 1860934 + Xaa-Pro dipeptidase Belongs to the IMPACT family%3B KEGG: sph:MGAS10270_Spy1444 Xaa-Pro dipeptidase gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02038 BL14DL4_02039 BL14DL4_02039 BL14DL4_02039 1860949 1862025 + Putative transcriptional regulator YvhJ Belongs to the LytR/CpsA/Psr regulatory protein family gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02039 BL14DL4_02040 BL14DL4_02040 BL14DL4_02040 1862110 1862484 - uncharacterized protein gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02040 BL14DL4_02041 BL14DL4_02041 wecA wecA 1862604 1863668 - UDP-N-acetylglucosamine--undecaprenyl-phosphateN-acetylglucosaminephosphotransferase Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B. subtili%3B may also be involved in teichuronic acid biosynthesis (Probable)%3B Belongs to the glycosyltransferase 4 family%3B KEGG: bli:BL03358 UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02041 BL14DL4_02042 BL14DL4_02042 tuaH tuaH 1863799 1864980 - Putative teichuronic acid biosynthesis glycosyltransferase TuaH Belongs to the glycosyltransferase group 1 family%3B KEGG: bli:BL03357 teichuronic acid biosynthesis glycosyltransferase TuaH%3B Glycosyltransferases gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02042 BL14DL4_02043 BL14DL4_02043 tuaG tuaG 1865008 1865766 - putative glycosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: bso:BSNT_05412 teichuronic acid biosynthesis glycosyltransferase TuaG%3B Glycosyltransferases gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02043 BL14DL4_02044 BL14DL4_02044 BL14DL4_02044 1865796 1866470 - Teichuronic acid biosynthesis protein TuaF gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02044 BL14DL4_02045 BL14DL4_02045 BL14DL4_02045 1866512 1867966 - Teichuronic acid biosynthesis protein TuaE gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02045 BL14DL4_02046 BL14DL4_02046 galE galE 1868030 1868959 - UDP-glucose 4-epimerase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: dji:CH75_11130 UDP-glucose 4-epimerase gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02046 BL14DL4_02047 BL14DL4_02047 ugdH ugdH 1868977 1870311 - UDP-glucose 6-dehydrogenase Catalyzes the conversion of UDP-glucose into UDP- glucuronate%2C one of the precursors of teichuronic acid. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: bso:BSNT_05418 UDPglucose 6-dehydrogenase gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02047 BL14DL4_02048 BL14DL4_02048 tuaC tuaC 1870506 1871684 - Putative teichuronic acid biosynthesis glycosyltransferase TuaC Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily%3B KEGG: bsu:BSU35590 teichuronic acid biosynthesis glycosyltransferase TuaC%3B Glycosyltransferases gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02048 BL14DL4_02049 BL14DL4_02049 BL14DL4_02049 1871707 1873146 - Teichuronic acid biosynthesis protein TuaB Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane. Belongs to the polysaccharide synthase family gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02049 BL14DL4_02050 BL14DL4_02050 BL14DL4_02050 1873170 1873829 - Putative undecaprenyl-phosphate N-acetylgalactosaminyl 1-phosphate transferase Might mediate the very first reaction in teichuronic synthesis%2C i. e. the formation of lipid-linked N-acetylglucosamine. Belongs to the bacterial sugar transferase family gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02050 BL14DL4_02051 BL14DL4_02051 BL14DL4_02051 1874061 1875548 - N-acetylmuramoyl-L-alanine amidase Autolysins are cell wall hydrolases involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teichoic acid-endowed peptidoglycan. LytC is required for efficient swarming motility but not at the level of cell separation or flagellum biosynthesis. Rather%2C LytC appears to be important for proper flagellar function%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bli:BL03348 N-acetylmuramoyl-L-alanine amidase gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02051 BL14DL4_02052 BL14DL4_02052 BL14DL4_02052 1875633 1877777 - N-acetylmuramoyl-L-alanine amidase KEGG: csq:CSCA_5254 N-acetylmuramoyl-L-alanine amidase gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02052 BL14DL4_02053 BL14DL4_02053 BL14DL4_02053 1877807 1878127 - Membrane-bound protein LytA gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02053 BL14DL4_02054 BL14DL4_02054 BL14DL4_02054 1878325 1879245 + Transcriptional regulator LytR Attenuator role for operon expression%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02054 BL14DL4_02055 BL14DL4_02055 wecB wecB 1879479 1880621 - UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine%2C a precursor of the teichoic acid linkage unit%3B Belongs to the UDP-N-acetylglucosamine 2-epimerase family%3B KEGG: cfu:CFU_3660 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02055 BL14DL4_02056 BL14DL4_02056 ugp2 ugp2 1880998 1881876 + UTP--glucose-1-phosphate uridylyltransferase Belongs to the UDPGP type 2 family%3B KEGG: pmr:PMI1490 UTP--glucose-1-phosphate uridylyltransferase gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02056 BL14DL4_02057 BL14DL4_02057 tagH tagH 1881947 1882858 - Teichoic-acid-transporting ATPase Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3. A. 1. 104. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU35700 teichoic acid transport system ATP-binding protein gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02057 BL14DL4_02058 BL14DL4_02058 BL14DL4_02058 1882879 1883706 - Teichoic acid translocation permease protein TagG Part of the ABC transporter complex TagGH (TC 3. A. 1. 34. 1) involved in exporting the two types of intracellularly synthesized teichoic acids. Probably responsible for the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02058 BL14DL4_02059 BL14DL4_02059 tagF tagF 1883911 1887414 - CDP-glycerol glycerophosphotransferase Catalyzes the addition of a second single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%2C to complete the linkage unit%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: lgr:LCGT_1240 CDP-glycerol glycerophosphotransferase gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02059 BL14DL4_02060 BL14DL4_02060 BL14DL4_02060 1887411 1887527 - hypothetical protein gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02060 BL14DL4_02061 BL14DL4_02061 BL14DL4_02061 1888112 1890247 - CDP-glycerol glycerophosphotransferase Is responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of glycerol phosphate units from CDP-glycerol to the disaccharide linkage unit. Synthesizes polymers of approximately 35 glycerol phosphate units in length%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bli:BL02463 CDP-glycerol glycerophosphotransferase gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02061 BL14DL4_02062 BL14DL4_02062 tagD tagD 1890388 1890783 - Glycerol-3-phosphate cytidylyltransferase Provides activated glycerol phosphate for teichoic acid synthesis%2C via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF. Belongs to the cytidylyltransferase family%3B KEGG: ecc:c3696 glycerol-3-phosphate cytidylyltransferase gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02062 BL14DL4_02063 BL14DL4_02063 tagA tagA 1891139 1891921 + N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol%2C a key lipid intermediate in the de novo synthesis of teichoic acid%3B Belongs to the glycosyltransferase 26 family%3B KEGG: bso:BSNT_05454 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02063 BL14DL4_02064 BL14DL4_02064 tarL tarL 1891941 1893104 + CDP-ribitol ribitolphosphotransferase Catalyzes the addition of a first single glycerol-P residue to the prenolpyrophosphate-linked disaccharide%3B Belongs to the CDP-glycerol glycerophosphotransferase family%3B KEGG: bsl:A7A1_1141 CDP-ribitol ribitolphosphotransferase gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02064 BL14DL4_02065 BL14DL4_02065 BL14DL4_02065 1893133 1895763 - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cell wall hydrolase not involved in cell autolysis%2C competence%2C sporulation or germination. It hydrolyzes the beta-1%2C4 glycan bond between the N-acetylglucosaminyl and the N- acetylmuramoyl residues in the glycan chain%3B Belongs to the glycosyl hydrolase 73 family%3B Contains 3 SPOR domains%3B KEGG: bli:BL02465 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02065 BL14DL4_02066 BL14DL4_02066 BL14DL4_02066 1895892 1896842 - Mannose-6-phosphate isomerase Belongs to the mannose-6-phosphate isomerase type 1 family%3B KEGG: bsu:BSU35790 mannose-6-phosphate isomerase gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02066 BL14DL4_02067 BL14DL4_02067 nrdG nrdG 1896998 1897510 - [Formate-C-acetyltransferase]-activating enzyme Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical%2C using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. Belongs to the organic radical-activating enzymes family%3B KEGG: bld:BLi03823 anaerobic ribonucleoside-triphosphate reductase activating protein gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02067 BL14DL4_02068 BL14DL4_02068 nrdD nrdD 1897459 1899327 - Ribonucleoside-triphosphate reductase Belongs to the anaerobic ribonucleoside-triphosphate reductase family%3B Contains 1 glycine radical domain%3B KEGG: bli:BL02468 ribonucleoside-triphosphate reductase gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02068 BL14DL4_02069 BL14DL4_02069 BL14DL4_02069 1899495 1900481 - 2-keto-3-deoxygluconate permease The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell%2C where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)%3B Belongs to the KdgT transporter family gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02069 BL14DL4_02070 BL14DL4_02070 BL14DL4_02070 1900566 1901180 - 2-dehydro-3-deoxy-phosphogluconate aldolase Belongs to the KHG/KDPG aldolase family%3B KEGG: bli:BL02470 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02070 BL14DL4_02071 BL14DL4_02071 kdgK kdgK 1901186 1902151 - 2-dehydro-3-deoxygluconokinase Involved in the degradation of glucose via the semi- phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2- keto-3-deoxy-6-phosphogluconate (KDPG)%3B Belongs to the carbohydrate kinase pfkB family%3B KEGG: bma:BMA0961 2-dehydro-3-deoxygluconokinase gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02071 BL14DL4_02072 BL14DL4_02072 BL14DL4_02072 1902254 1903270 - putative HTH-type transcriptional regulator EndR Putative repressor of the endoglucanase operon. Contains 1 HTH lacI-type DNA-binding domain gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02072 BL14DL4_02073 BL14DL4_02073 kduI kduI 1903526 1904353 + 5-dehydro-4-deoxy-D-glucuronate isomerase Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate%3B Belongs to the KduI family%3B KEGG: cja:CJA_0169 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02073 BL14DL4_02074 BL14DL4_02074 kduD kduD 1904369 1905133 + 2-deoxy-D-gluconate 3-dehydrogenase Catalyzes the reversible reduction of 2%2C5-diketo-3- deoxygluconate (DKII or 4%2C6-dihydroxy-2%2C5-dioxohexanoate) into 2- keto-3-deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH (Ref. 4). To a lesser extent%2C can also reduce 5-keto-D-gluconate and oxidize D-gluconate and 1%2C2- propanediol (PubMed:24509771). Together with KduI%2C seems to play a role in the catabolism of hexuronates under osmotic stress conditions%2C substituting for the regular hexuronate degrading enzymes UxaABC and UxuAB whose expression is repressed in these conditions (PubMed:23437267). In vitro%2C also exhibits NADH- dependent 20-ketosteroid reductase activity against eukaryotic steroid hormone 11-deoxycorticosterone (11-DOC)%2C which is converted into the product 4-pregnen-20%2C21-diol-3-one. In addition to 11-DOC%2C five other C21 steroid compounds (11-deoxycortisol%2C cortisol%2C corticosterone%2C cortisone%2C and 21-hydroxypregnenolone) are reduced by KduD%2C but steroids lacking the hydroxyl group at C21 position%2C such as pregnenolone%2C testosterone propionate%2C cortisone acetate%2C or progesterone%2C cannot be used as substrate (PubMed:24509771)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02435 2-deoxy-D-gluconate 3-dehydrogenase gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02074 BL14DL4_02075 BL14DL4_02075 frmA frmA 1905177 1906310 - S-(hydroxymethyl)glutathione dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily%3B KEGG: bsu:BSU26970 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02075 BL14DL4_02076 BL14DL4_02076 BL14DL4_02076 1906452 1906589 + hypothetical protein gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02076 BL14DL4_02077 BL14DL4_02077 BL14DL4_02077 1906641 1908014 - Putative metabolite transport protein YwtG Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02077 BL14DL4_02078 BL14DL4_02078 BL14DL4_02078 1908313 1909269 + Putative transcriptional regulator YwtF Belongs to the LytR/CpsA/Psr regulatory protein family gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02078 BL14DL4_02079 BL14DL4_02079 BL14DL4_02079 1909459 1910319 + Putative phosphatase YcsE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02079 BL14DL4_02080 BL14DL4_02080 BL14DL4_02080 1910370 1911614 - Gamma-DL-glutamyl hydrolase Cleaves%2C in an endo-type manner%2C the gamma-glutamyl bond between D-glutamate and L-glutamate of poly-gamma-glutamate (PGA). Belongs to the peptidase C40 family%3B KEGG: lfu:HR49_15335 peptidoglycan endopeptidase LytF%3B Acting on peptide bonds (peptidases) gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02080 BL14DL4_02081 BL14DL4_02081 BL14DL4_02081 1912070 1912237 - uncharacterized protein gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02081 BL14DL4_02082 BL14DL4_02082 BL14DL4_02082 1912234 1913403 - Capsule biosynthesis protein CapA Essential for the synthesis of the polyglutamate capsule of B. anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC. Belongs to the CapA family gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02082 BL14DL4_02083 BL14DL4_02083 BL14DL4_02083 1913423 1913872 - Capsule biosynthesis protein CapC gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02083 BL14DL4_02084 BL14DL4_02084 BL14DL4_02084 1913888 1915069 - PGA synthase CapB Catalyzes the biosynthesis of PGA (gamma-polyglutamic acid) from L-glutamate. Both the 44-kDa and the 33-kDa forms are required for PGA synthesis gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02084 BL14DL4_02085 BL14DL4_02085 BL14DL4_02085 1915859 1916839 + Sucrose operon repressor Repressor for the csc operon. Binds D-fructose as an inducer (By similarity)%3B Contains 1 HTH lacI-type DNA-binding domain gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02085 BL14DL4_02086 BL14DL4_02086 rbsK rbsK 1916842 1917723 + Ribokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: hpas:JL26_09640 ribokinase gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02086 BL14DL4_02087 BL14DL4_02087 rbsD rbsD 1917720 1918115 + D-ribose pyranase Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose%3B Belongs to the RbsD / FucU family. RbsD subfamily%3B KEGG: cvi:CV_3019 D-ribose pyranase gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02087 BL14DL4_02088 BL14DL4_02088 BL14DL4_02088 1918153 1919634 + Sulfate/thiosulfate import ATP-binding protein CysA Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02088 BL14DL4_02089 BL14DL4_02089 BL14DL4_02089 1919636 1920598 + Ribose transport system permease protein RbsC Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02089 BL14DL4_02090 BL14DL4_02090 BL14DL4_02090 1920613 1921527 + D-xylose-binding periplasmic protein Involved in the high-affinity D-xylose membrane transport system. Binds with high affinity to xylose (By similarity)%3B Belongs to the bacterial solute-binding protein 2 family gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02090 BL14DL4_02091 BL14DL4_02091 alsD alsD 1921806 1922567 - Acetolactate decarboxylase Converts acetolactate into acetoin%3B Belongs to the alpha-acetolactate decarboxylase family%3B KEGG: bli:BL02479 acetolactate decarboxylase gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02091 BL14DL4_02092 BL14DL4_02092 BL14DL4_02092 1922620 1924338 - Acetolactate synthase Belongs to the TPP enzyme family%3B KEGG: bli:BL02480 acetolactate synthase I/II/III large subunit gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02092 BL14DL4_02093 BL14DL4_02093 BL14DL4_02093 1924499 1925377 + HTH-type transcriptional regulator BenM Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes%2C which can be regulated by CatM. Binds to the inducers cis%2Ccis-muconate and benzoate. Contains 1 HTH lysR-type DNA-binding domain gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02093 BL14DL4_02094 BL14DL4_02094 BL14DL4_02094 1925464 1927041 - Gamma-glutamyltransferase Belongs to the gamma-glutamyltransferase family%3B KEGG: bli:BL02481 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02094 BL14DL4_02095 BL14DL4_02095 BL14DL4_02095 1927278 1927754 + putative HTH-type transcriptional regulator YwrC Contains 1 HTH asnC-type DNA-binding domain gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02095 BL14DL4_02096 BL14DL4_02096 BL14DL4_02096 1927776 1928360 + putative transporter YwrB Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02096 BL14DL4_02097 BL14DL4_02097 BL14DL4_02097 1928357 1928893 + putative transporter YwrA Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02097 BL14DL4_02098 BL14DL4_02098 BL14DL4_02098 1928991 1929743 - Protein-tyrosine-phosphatase Required for the biosynthesis of type 1 capsular polysaccharide. Belongs to the CpsB/CapC family%3B KEGG: pfv:Psefu_1694 protein-tyrosine phosphatase gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02098 BL14DL4_02099 BL14DL4_02099 BL14DL4_02099 1929770 1930492 - uncharacterized protein Belongs to the CpsC/CapA family gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02099 BL14DL4_02100 BL14DL4_02100 BL14DL4_02100 1930718 1930861 - uncharacterized protein gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02100 BL14DL4_02101 BL14DL4_02101 BL14DL4_02101 1931077 1932675 + uncharacterized protein Contains 1 SWIM-type zinc finger gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02101 BL14DL4_02102 BL14DL4_02102 BL14DL4_02102 1932662 1935427 + Non-specific serine/threonine protein kinase Belongs to the SNF2/RAD54 helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: stp:Strop_3363 non-specific serine/threonine protein kinase gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02102 BL14DL4_02103 BL14DL4_02103 BL14DL4_02103 1935424 1935570 - hypothetical protein gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02103 BL14DL4_02104 BL14DL4_02104 BL14DL4_02104 1935824 1936702 - Putative phosphatase Belongs to the HAD-like hydrolase superfamily. Cof family gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02104 BL14DL4_02105 BL14DL4_02105 BL14DL4_02105 1936718 1937488 - HTH-type transcriptional repressor GlcR Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars%3B Contains 1 HTH deoR-type DNA-binding domain gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02105 BL14DL4_02106 BL14DL4_02106 fsaB fsaB 1937631 1938296 - Fructose-6-phosphate aldolase Catalyzes the reversible formation of fructose 6- phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction%3B Belongs to the transaldolase family. Type 3A subfamily%3B KEGG: bli:BL02486 fructose-6-phosphate aldolase 2%3B Aldehyde-lyases gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02106 BL14DL4_02107 BL14DL4_02107 srlD srlD 1938317 1939102 - Sorbitol-6-phosphate 2-dehydrogenase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02488 sorbitol-6-phosphate 2-dehydrogenase gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02107 BL14DL4_02108 BL14DL4_02108 srlB srlB 1939117 1939488 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIA type-5 domain%3B KEGG: bli:BL02487 PTS system%2C glucitol/sorbitol-specific IIA component gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02108 BL14DL4_02109 BL14DL4_02109 srlE srlE 1939513 1940520 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIB type-5 domain%3B KEGG: bli:BL02489 PTS system%2C glucitol/sorbitol-specific IIB component gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02109 BL14DL4_02110 BL14DL4_02110 BL14DL4_02110 1940538 1941086 - Glucitol/sorbitol permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in glucitol/sorbitol transport. Contains 1 PTS EIIC type-5 domain gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02110 BL14DL4_02111 BL14DL4_02111 BL14DL4_02111 1941083 1941526 - Glucitol operon activator protein gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02111 BL14DL4_02112 BL14DL4_02112 BL14DL4_02112 1941523 1942485 - Sorbitol operon regulator Positively regulates%2C in the presence of L-sorbose%2C and negatively regulates%2C in the absence of L-sorbose%2C the transcription of the sor operon. Belongs to the SorC transcriptional regulatory family gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02112 BL14DL4_02113 BL14DL4_02113 BL14DL4_02113 1942707 1943054 - Single-stranded DNA-binding protein Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02113 BL14DL4_02114 BL14DL4_02114 BL14DL4_02114 1943160 1943531 - uncharacterized protein gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02114 BL14DL4_02115 BL14DL4_02115 BL14DL4_02115 1943713 1944126 + uncharacterized protein gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02115 BL14DL4_02116 BL14DL4_02116 BL14DL4_02116 1944167 1944547 - Large-conductance mechanosensitive channel Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell%3B Belongs to the MscL family gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02116 BL14DL4_02117 BL14DL4_02117 fabZ fabZ 1944617 1945051 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs%3B Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bli:BL02496 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02117 BL14DL4_02118 BL14DL4_02118 BL14DL4_02118 1945245 1946060 - Flagellar hook-basal body complex protein FlhP Belongs to the flagella basal body rod proteins family gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02118 BL14DL4_02119 BL14DL4_02119 BL14DL4_02119 1946116 1946955 - Flagellar hook-basal body complex protein FlhO Not required for motility. Belongs to the flagella basal body rod proteins family gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02119 BL14DL4_02120 BL14DL4_02120 BL14DL4_02120 1947164 1948165 - MreB-like protein Belongs to the FtsA/MreB family gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02120 BL14DL4_02121 BL14DL4_02121 BL14DL4_02121 1948351 1948626 - Stage III sporulation protein This protein regulates the transcription of sigK%2C which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). Contains 1 HTH deoR-type DNA-binding domain gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02121 BL14DL4_02122 BL14DL4_02122 BL14DL4_02122 1948963 1949391 + putative HTH-type transcriptional regulator YwoH Contains 1 HTH marR-type DNA-binding domain gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02122 BL14DL4_02123 BL14DL4_02123 BL14DL4_02123 1949395 1950588 + putative MFS-type transporter YwoG Belongs to the major facilitator superfamily gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02123 BL14DL4_02124 BL14DL4_02124 BL14DL4_02124 1950738 1951316 + Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the BcrC/YbjG family%3B KEGG: bli:BL02453 undecaprenyl-diphosphatase gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02124 BL14DL4_02125 BL14DL4_02125 ppaC ppaC 1951359 1952288 - Inorganic diphosphatase Belongs to the PPase class C family%3B KEGG: bsu:BSU40550 manganese-dependent inorganic pyrophosphatase gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02125 BL14DL4_02126 BL14DL4_02126 BL14DL4_02126 1952423 1953244 - putative manganese catalase Belongs to the manganese catalase family gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02126 BL14DL4_02127 BL14DL4_02127 BL14DL4_02127 1953374 1954111 + uncharacterized protein gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02127 BL14DL4_02128 BL14DL4_02128 BL14DL4_02128 1954149 1954556 - IMP dehydrogenase Contains 2 CBS domains%3B KEGG: azo:azo1748 IMP dehydrogenase gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02128 BL14DL4_02129 BL14DL4_02129 BL14DL4_02129 1954619 1955575 - Magnesium transport protein CorA Mediates influx of magnesium ions%3B Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02129 BL14DL4_02130 BL14DL4_02130 BL14DL4_02130 1955736 1957034 + UPF0053 protein YqhB Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02130 BL14DL4_02131 BL14DL4_02131 BL14DL4_02131 1957195 1958406 + Ammonium transporter NrgA Functions as an ammonium and methylammonium transporter in the absence of glutamine. Required for ammonium utilization at low concentrations or at low pH values%2C when ammonium is the single nitrogen source. Required for binding of NrgB to the membrane%3B Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02131 BL14DL4_02132 BL14DL4_02132 BL14DL4_02132 1958425 1958775 + Nitrogen regulatory PII-like protein Required for full induction of the nrgAB operon under conditions of ammonium limitation%3B Belongs to the P(II) protein family gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02132 BL14DL4_02133 BL14DL4_02133 BL14DL4_02133 1958824 1959396 - Endopeptidase Clp Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins%3B Belongs to the peptidase S14 family%3B KEGG: dma:DMR_28170 ATP-dependent Clp protease%2C protease subunit gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02133 BL14DL4_02134 BL14DL4_02134 BL14DL4_02134 1959410 1960015 - hypothetical protein gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02134 BL14DL4_02135 BL14DL4_02135 BL14DL4_02135 1960152 1961027 - Stage II sporulation protein Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02135 BL14DL4_02136 BL14DL4_02136 BL14DL4_02136 1961220 1961717 + Phosphinothricin acetyltransferase This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Inactivates PTT by transfer of an acetyl group (By similarity)%3B Belongs to the acetyltransferase family. PAT/BAR subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL04040 phosphinothricin acetyltransferase gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02136 BL14DL4_02137 BL14DL4_02137 BL14DL4_02137 1961765 1962208 - uncharacterized protein gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02137 BL14DL4_02138 BL14DL4_02138 BL14DL4_02138 1962440 1963906 + Major cardiolipin synthase ClsA Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bli:BL04039 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02138 BL14DL4_02139 BL14DL4_02139 BL14DL4_02139 1964046 1965476 + hypothetical protein gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02139 BL14DL4_02140 BL14DL4_02140 BL14DL4_02140 1965507 1966940 - putative transport protein HsrA Belongs to the major facilitator superfamily. EmrB family gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02140 BL14DL4_02141 BL14DL4_02141 BL14DL4_02141 1966933 1967160 - uncharacterized protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02141 BL14DL4_02142 BL14DL4_02142 BL14DL4_02142 1967173 1974330 - Dimodular nonribosomal peptide synthase Specifically adenylates threonine and glycine%2C and loads them onto their corresponding peptidyl carrier domains%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 2 acyl carrier domains gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02142 BL14DL4_02143 BL14DL4_02143 entB entB 1974345 1975271 - Isochorismatase Belongs to the isochorismatase family%3B Contains 1 acyl carrier domain%3B KEGG: bli:BL04023 bifunctional isochorismate lyase / aryl carrier protein gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02143 BL14DL4_02144 BL14DL4_02144 entE entE 1975296 1976918 - (2%2C3-dihydroxybenzoyl)adenylate synthase Activation of the carboxylate group of 2%2C3-dihydroxy- benzoate (DHB)%2C via ATP-dependent PPi exchange reactions%2C to the acyladenylate. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL04022 2%2C3-dihydroxybenzoate-AMP ligase gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02144 BL14DL4_02145 BL14DL4_02145 entC entC 1976932 1978122 - Isochorismate synthase Belongs to the isochorismate synthase family%3B KEGG: bli:BL04021 isochorismate synthase gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02145 BL14DL4_02146 BL14DL4_02146 BL14DL4_02146 1978147 1978917 - 2-deoxy-D-gluconate 3-dehydrogenase Catalyzes the NADPH-dependent reduction of long chain acyl-CoA (with chain lengths of 14 to 22 carbons) to the corresponding aldehyde%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: yel:LC20_03973 2-deoxy-D-gluconate 3-dehydrogenase gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02146 BL14DL4_02147 BL14DL4_02147 BL14DL4_02147 1979148 1979996 - Ferri-bacillibactin esterase BesA Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex%2C leading to the formation of bacillibactin monomers and to cytosolic iron release%2C thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB)%2C however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB%3B Belongs to the esterase D family gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02147 BL14DL4_02148 BL14DL4_02148 BL14DL4_02148 1980037 1981056 - Iron-uptake system permease protein FeuC Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02148 BL14DL4_02149 BL14DL4_02149 BL14DL4_02149 1981049 1982053 - Iron-uptake system permease protein FeuB Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02149 BL14DL4_02150 BL14DL4_02150 BL14DL4_02150 1982071 1983027 - Iron-uptake system-binding protein Involved in the uptake of iron%3B Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02150 BL14DL4_02151 BL14DL4_02151 BL14DL4_02151 1983119 1984714 - HTH-type transcriptional activator Btr In iron-limited conditions%2C activates expression of the feuABCybbA operon%2C which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin%3B Contains 1 Fe/B12 periplasmic-binding domain%3B Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02151 BL14DL4_02152 BL14DL4_02152 BL14DL4_02152 1985114 1985434 + uncharacterized protein gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02152 BL14DL4_02153 BL14DL4_02153 BL14DL4_02153 1985479 1986120 - uncharacterized protein gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02153 BL14DL4_02154 BL14DL4_02154 BL14DL4_02154 1986195 1986596 - Putative HTH-type transcriptional regulator YwnA Contains 1 HTH rrf2-type DNA-binding domain gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02154 BL14DL4_02155 BL14DL4_02155 BL14DL4_02155 1986768 1987307 + hypothetical protein gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02155 BL14DL4_02156 BL14DL4_02156 BL14DL4_02156 1987188 1987667 - putative membrane protein YwmF gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02156 BL14DL4_02157 BL14DL4_02157 moaA moaA 1987817 1988842 - Cyclic pyranopterin phosphate synthase Catalyzes%2C together with MoaC%2C the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the radical SAM superfamily. MoaA family%3B KEGG: bsu:BSU36700 cyclic pyranopterin phosphate synthase gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02157 BL14DL4_02158 BL14DL4_02158 BL14DL4_02158 1988858 1989649 - Protein FdhD like protein Necessary for formate dehydrogenase activity%3B Belongs to the FdhD family gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02158 BL14DL4_02159 BL14DL4_02159 BL14DL4_02159 1989911 1991173 + putative MFS-type transporter Belongs to the major facilitator superfamily gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02159 BL14DL4_02160 BL14DL4_02160 narB narB 1991206 1993557 + Ferredoxin--nitrate reductase In the C-terminal sectio%3B belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 2Fe-2S ferredoxin-type domain%3B Contains 2 4Fe-4S ferredoxin-type domains%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: pmx:PERMA_0888 ferredoxin-nitrate reductase gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02160 BL14DL4_02161 BL14DL4_02161 BL14DL4_02161 1993604 1994275 - uncharacterized protein Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02161 BL14DL4_02162 BL14DL4_02162 BL14DL4_02162 1994669 1995355 - uncharacterized protein Contains 1 VWFA domain%3B To B. subtilis YwmD gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02162 BL14DL4_02163 BL14DL4_02163 BL14DL4_02163 1995673 1996689 - Stage II sporulation protein D gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02163 BL14DL4_02164 BL14DL4_02164 murA murA 1996887 1998197 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: maq:Maqu_2703 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02164 BL14DL4_02165 BL14DL4_02165 BL14DL4_02165 1998230 1998973 - uncharacterized protein gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02165 BL14DL4_02166 BL14DL4_02166 BL14DL4_02166 1999115 1999348 - putative membrane protein YwzB gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02166 BL14DL4_02167 BL14DL4_02167 BL14DL4_02167 1999732 2000127 - ATP synthase epsilon chain Produces ATP from ADP in the presence of a proton gradient across the membrane%3B Belongs to the ATPase epsilon chain family gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02167 BL14DL4_02168 BL14DL4_02168 atpD atpD 2000151 2001572 - H(+)-transporting two-sector ATPase Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: bsu:BSU36810 F-type H+-transporting ATPase subunit beta gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02168 BL14DL4_02169 BL14DL4_02169 BL14DL4_02169 2001598 2002452 - ATP synthase gamma chain Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex%3B Belongs to the ATPase gamma chain family gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02169 BL14DL4_02170 BL14DL4_02170 atpA atpA 2002541 2004049 - H(+)-transporting two-sector ATPase Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit%3B Belongs to the ATPase alpha/beta chains family%3B KEGG: hhm:BN341_p0008 F-type H+-transporting ATPase subunit alpha gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02170 BL14DL4_02171 BL14DL4_02171 BL14DL4_02171 2004057 2004611 - ATP synthase subunit delta F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction%3B Belongs to the ATPase delta chain family gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02171 BL14DL4_02172 BL14DL4_02172 BL14DL4_02172 2004608 2005126 - ATP synthase subunit F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Component of the F(0) channel%2C it forms part of the peripheral stalk%2C linking F(1) to F(0)%3B Belongs to the ATPase B chain family gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02172 BL14DL4_02173 BL14DL4_02173 BL14DL4_02173 2005301 2005513 - ATP synthase subunit F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains%2C F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel%2C linked together by a central stalk and a peripheral stalk. During catalysis%2C ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation%3B Key component of the F(0) channe%3B it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits%3B Belongs to the ATPase C chain family gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02173 BL14DL4_02174 BL14DL4_02174 BL14DL4_02174 2005563 2006297 - ATP synthase subunit Key component of the proton channe%3B it plays a direct role in the translocation of protons across the membrane%3B Belongs to the ATPase A chain family gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02174 BL14DL4_02175 BL14DL4_02175 BL14DL4_02175 2006305 2006688 - ATP synthase protein A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex. Belongs to the bacterial AtpI family gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02175 BL14DL4_02176 BL14DL4_02176 uprT uprT 2007089 2007718 - Uracil phosphoribosyltransferase Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate%3B Belongs to the UPRTase family%3B KEGG: bsu:BSU36890 uracil phosphoribosyltransferase gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02176 BL14DL4_02177 BL14DL4_02177 glyA glyA 2007845 2009092 - Glycine hydroxymethyltransferase Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines%2C thymidylate%2C methionine%2C and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids%2C producing glycine and aldehydes%2C via a retro-aldol mechanism%3B Belongs to the SHMT family%3B KEGG: bsu:BSU36900 glycine hydroxymethyltransferase gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02177 BL14DL4_02178 BL14DL4_02178 BL14DL4_02178 2009318 2009860 - UPF0340 protein Belongs to the UPF0340 family gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02178 BL14DL4_02179 BL14DL4_02179 rpiB rpiB 2009876 2010325 - Ribose-5-phosphate isomerase Belongs to the LacAB/RpiB family%3B KEGG: bli:BL03989 ribose 5-phosphate isomerase B gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02179 BL14DL4_02180 BL14DL4_02180 BL14DL4_02180 2010468 2010923 - Protein-tyrosine-phosphatase Catalyzes the specific dephosphorylation of phosphoarginine residues in a large number of proteins. Counteracts the protein arginine kinase McsB in vivo. Can dephosphorylate CtsR-%3B thus%2C can restore the DNA-binding ability of the CtsR repressor by reversing the McsB-mediated phosphorylation. Is the only active pArg phosphatase present in B. subtilis. Exhibits almost no activity against pSer%2C pThr%2C or pTyr peptides. Appears to play a role in B. subtilis stress resistance. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: bsu:BSU36930 protein-tyrosine phosphatase gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02180 BL14DL4_02181 BL14DL4_02181 BL14DL4_02181 2011074 2011634 - Putative manganese efflux pump MntP Probably functions as a manganese efflux pump%3B Belongs to the MntP (TC 9. B. 29) family gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02181 BL14DL4_02182 BL14DL4_02182 tsaC tsaC 2011709 2012758 - L-threonylcarbamoyladenylate synthase Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine%2C HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate%2C with the release of diphosphate. Is also able to catalyze the reverse reaction in vitro%2C i. e. the formation of ATP from TC-AMP and PPi%3B Belongs to the SUA5 family%3B Contains 1 YrdC-like domain%3B KEGG: bld:BLi03940 L-threonylcarbamoyladenylate synthase gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02182 BL14DL4_02183 BL14DL4_02183 BL14DL4_02183 2012910 2013317 - uncharacterized protein gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02183 BL14DL4_02184 BL14DL4_02184 BL14DL4_02184 2013697 2014362 - Stage II sporulation protein gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02184 BL14DL4_02185 BL14DL4_02185 BL14DL4_02185 2014482 2015666 - Glucose/mannose transporter GlcP Can transport glucose%2C mannose%2C 2-deoxyglucose and methyl alpha-glucoside%2C but not galactose%3B Belongs to the major facilitator superfamily gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02185 BL14DL4_02186 BL14DL4_02186 ntdC ntdC 2015743 2016789 - Glucose-6-phosphate 3-dehydrogenase Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the oxidation of glucose 6-phosphate to 3-oxo-D-glucose 6-phosphate. It can only use NAD%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL03982 glucose-6-phosphate 3-dehydrogenase gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02186 BL14DL4_02187 BL14DL4_02187 ntdB ntdB 2016803 2017651 - Kanosamine-6-phosphate phosphatase Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the dephosphorylation of kanosamine 6- phosphate to yield kanosamine. There is a trace amount of activity using glucosamine-6-phosphate%3B Belongs to the HAD-like hydrolase superfamily. Cof family%3B KEGG: bli:BL03981 kanosamine-6-phosphate phosphatase gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02187 BL14DL4_02188 BL14DL4_02188 ntdA ntdA 2017638 2018990 - 3-dehydro-glucose-6-phosphate--glutamate transaminase Involved in the biosynthesis of kanosamine (3-amino-3- deoxy-D-glucose)%2C which is known to have antibiotic and antifungal properties%2C and to be a precursor of the antibiotic neotrehalosadiamine (3%2C3'-diamino-3%2C3'-dideoxy-alpha%2Cbeta- trehalose (NTD)). Catalyzes the reversible pyridoxal phosphate- dependent transamination of 3-dehydro-alpha-D-glucose 6-phosphate to form alpha-D-kanosamine-6-phosphate. It can only use alpha- anomer and glutamate is the only amino donor%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: bli:BL03980 3-dehydro-glucose-6-phosphate---glutamate transaminase gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02188 BL14DL4_02189 BL14DL4_02189 BL14DL4_02189 2019058 2020047 + NTD biosynthesis operon regulator NtdR Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription%3B Contains 1 HTH lacI-type DNA-binding domain gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02189 BL14DL4_02190 BL14DL4_02190 hemK hemK 2020380 2021246 - Peptide chain release factor N(5)-glutamine methyltransferase Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif%3B Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily%3B KEGG: bsu:BSU37000 release factor glutamine methyltransferase gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02190 BL14DL4_02191 BL14DL4_02191 BL14DL4_02191 2021249 2022319 - Peptide chain release factor Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA%3B Belongs to the prokaryotic/mitochondrial release factor family gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02191 BL14DL4_02192 BL14DL4_02192 BL14DL4_02192 2022455 2022838 + uncharacterized protein gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02192 BL14DL4_02193 BL14DL4_02193 BL14DL4_02193 2022975 2023535 + Chromosome-anchoring protein RacA Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells%2C thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome%2C causing condensation of the chromosome and its remodeling into an elongated%2C anchored structure%3B Belongs to the RacA family gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02193 BL14DL4_02194 BL14DL4_02194 BL14DL4_02194 2023590 2024546 - putative transporter YwkB Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02194 BL14DL4_02195 BL14DL4_02195 BL14DL4_02195 2024725 2026428 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B KEGG: bsu:BSU37050 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02195 BL14DL4_02196 BL14DL4_02196 BL14DL4_02196 2026767 2027351 - Thymidine kinase Belongs to the thymidine kinase family%3B KEGG: bsu:BSU37060 thymidine kinase gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02196 BL14DL4_02197 BL14DL4_02197 BL14DL4_02197 2027430 2027630 - 50S ribosomal protein L31 Binds the 23S rRNA%3B Belongs to the ribosomal protein L31P family. Type A subfamily gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02197 BL14DL4_02198 BL14DL4_02198 BL14DL4_02198 2027758 2029041 - Transcription termination factor Rho Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA%2C activation of Rho's RNA-dependent ATPase activity%2C and release of the mRNA from the DNA template%3B Belongs to the Rho family gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02198 BL14DL4_02199 BL14DL4_02199 glpX glpX 2029503 2030468 - Fructose-bisphosphatase Catalyzes the hydrolysis of fructose 1%2C6-bisphosphate (Fru 1%2C6-P2) and sedoheptulose 1%2C7-bisphosphate (Sed 1%2C7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate%2C respectively%3B Belongs to the FBPase class 2 family%3B KEGG: hap:HAPS_0273 fructose-1%2C6-bisphosphatase II gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02199 BL14DL4_02200 BL14DL4_02200 BL14DL4_02200 2030535 2031824 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine%3B Belongs to the EPSP synthase family. MurA subfamily%3B KEGG: bsu:BSU37100 UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02200 BL14DL4_02201 BL14DL4_02201 talA talA 2032082 2032717 - Transaldolase Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway%3B Belongs to the transaldolase family. Type 3B subfamily%3B KEGG: spiu:SPICUR_04415 transaldolase gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02201 BL14DL4_02202 BL14DL4_02202 fbaA fbaA 2032950 2033807 - Fructose-bisphosphate aldolase Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1%2C6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis%3B Belongs to the class II fructose-bisphosphate aldolase family%3B KEGG: bsu:BSU37120 fructose-bisphosphate aldolase%2C class II gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02202 BL14DL4_02203 BL14DL4_02203 BL14DL4_02203 2034010 2034384 - DNA-binding response regulator MtrA Member of the two-component regulatory system MtrA/MtrB%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02203 BL14DL4_02204 BL14DL4_02204 BL14DL4_02204 2034561 2035091 + uncharacterized protein gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02204 BL14DL4_02205 BL14DL4_02205 pyrG pyrG 2035225 2036832 - CTP synthase (glutamine hydrolyzing) Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B Belongs to the CTP synthase family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: sbw:TGUWTKB_3070 CTP synthase gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02205 BL14DL4_02206 BL14DL4_02206 BL14DL4_02206 2037087 2037602 - putative DNA-directed RNA polymerase subunit delta Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit%2C RNAP displays an increased specificity of transcription%2C a decreased affinity for nucleic acids%2C and an increased efficiency of RNA synthesis because of enhanced recycling%3B Belongs to the RpoE family gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02206 BL14DL4_02207 BL14DL4_02207 BL14DL4_02207 2037904 2039043 - Acyl-CoA dehydrogenase Involved in the degradation of long-chain fatty acids. Belongs to the acyl-CoA dehydrogenase family%3B KEGG: rme:Rmet_5425 null%3B With other acceptors gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02207 BL14DL4_02208 BL14DL4_02208 BL14DL4_02208 2039065 2040195 - Acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bli:BL03927 null%3B With other acceptors gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02208 BL14DL4_02209 BL14DL4_02209 paaH paaH 2040208 2041071 - 3-hydroxybutyryl-CoA dehydrogenase Belongs to the 3-hydroxyacyl-CoA dehydrogenase family%3B KEGG: bli:BL03926 3-hydroxybutyryl-CoA dehydrogenase gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02209 BL14DL4_02210 BL14DL4_02210 BL14DL4_02210 2041087 2042265 - Acetyl-CoA C-acetyltransferase Belongs to the thiolase family%3B KEGG: bli:BL03925 acetyl-CoA C-acetyltransferase gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02210 BL14DL4_02211 BL14DL4_02211 BL14DL4_02211 2042363 2044477 - uncharacterized protein Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: gfo:GFO_1637 null%3B Oxidoreductases gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02211 BL14DL4_02212 BL14DL4_02212 BL14DL4_02212 2044627 2045817 + Minor cardiolipin synthase ClsB Involved in the biosynthesis of cardiolipin%3B Belongs to the phospholipase D family. Cardiolipin synthase subfamily%3B Contains 2 PLD phosphodiesterase domains%3B KEGG: bli:BL03965 cardiolipin synthase%3B Transferases for other substituted phosphate groups gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02212 BL14DL4_02213 BL14DL4_02213 BL14DL4_02213 2045892 2046158 + uncharacterized protein gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02213 BL14DL4_02214 BL14DL4_02214 rarS rarS 2046243 2047913 - Arginine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bli:BL03923 arginyl-tRNA synthetase gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02214 BL14DL4_02215 BL14DL4_02215 BL14DL4_02215 2047910 2048404 - putative beta-barrel protein YwiB gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02215 BL14DL4_02216 BL14DL4_02216 speB speB 2048496 2049368 - Agmatinase Catalyzes the formation of putrescine from agmatine%3B Belongs to the arginase family. Agmatinase subfamily%3B KEGG: bsu:BSU37490 agmatinase gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02216 BL14DL4_02217 BL14DL4_02217 speE speE 2049423 2050253 - Spermidine synthase Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1%2C4-diaminobutane) to yield spermidine%3B Belongs to the spermidine/spermine synthase family%3B Contains 1 PABS (polyamine biosynthesis) domain%3B KEGG: bli:BL03920 spermidine synthase gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02217 BL14DL4_02218 BL14DL4_02218 BL14DL4_02218 2050508 2051230 + hypothetical protein gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02218 BL14DL4_02219 BL14DL4_02219 BL14DL4_02219 2051358 2053433 + Penicillin-binding protein 2D Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall%2C the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane%3B In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02219 BL14DL4_02220 BL14DL4_02220 BL14DL4_02220 2053491 2054006 - uncharacterized protein gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02220 BL14DL4_02221 BL14DL4_02221 BL14DL4_02221 2054019 2054708 - Putative zinc metalloprotease YwhC Belongs to the peptidase M50B family gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02221 BL14DL4_02222 BL14DL4_02222 praC praC 2054789 2054974 + 2-hydroxymuconate tautomerase Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bli:BL03961 4-oxalocrotonate tautomerase gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02222 BL14DL4_02223 BL14DL4_02223 BL14DL4_02223 2055018 2055824 - hypothetical protein gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02223 BL14DL4_02224 BL14DL4_02224 BL14DL4_02224 2056011 2056514 - uncharacterized protein gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02224 BL14DL4_02225 BL14DL4_02225 BL14DL4_02225 2056545 2057843 - uncharacterized protein Contains 1 HD domain gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02225 BL14DL4_02226 BL14DL4_02226 BL14DL4_02226 2058083 2058307 - UPF0741 protein Belongs to the UPF0741 family gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02226 BL14DL4_02227 BL14DL4_02227 BL14DL4_02227 2058530 2059315 + Prespore-specific transcriptional regulator RsfA Seems to improve the efficiency of sporulation by fine- tuning the expression of genes in the sigma F regulon%2C particularly the timing of their expression. Negatively regulates spoIIR and its own synthesis. Contains 1 Myb-like domain gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02227 BL14DL4_02228 BL14DL4_02228 BL14DL4_02228 2059496 2059825 + uncharacterized protein gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02228 BL14DL4_02229 BL14DL4_02229 lipL lipL 2059980 2060930 - Octanoyl-[GcvH]:protein N-octanoyltransferase Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes%3B Belongs to the octanoyltransferase LipL family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bli:BL03912 octanoyl-(GcvH):protein N-octanoyltransferase gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02229 BL14DL4_02230 BL14DL4_02230 pobA pobA 2060927 2062132 - 4-hydroxybenzoate 3-monooxygenase KEGG: efe:EFER_4403 p-hydroxybenzoate 3-monooxygenase gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02230 BL14DL4_02231 BL14DL4_02231 BL14DL4_02231 2062148 2063524 - Benzoate transport protein Probable uptake of benzoate. Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2. A. 1. 15) family gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02231 BL14DL4_02232 BL14DL4_02232 hpaD hpaD 2063563 2064414 - 3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase KEGG: bli:BL03909 3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02232 BL14DL4_02233 BL14DL4_02233 BL14DL4_02233 2064438 2064629 - 2-hydroxymuconate tautomerase Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: ror:RORB6_15955 4-oxalocrotonate tautomerase gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02233 BL14DL4_02234 BL14DL4_02234 dmpH dmpH 2064647 2065432 - 2-oxo-3-hexenedioate decarboxylase Belongs to the hydratase/decarboxylase family%3B KEGG: bli:BL03907 2-oxo-3-hexenedioate decarboxylase gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02234 BL14DL4_02235 BL14DL4_02235 dmpC dmpC 2065447 2066931 - Aminomuconate-semialdehyde dehydrogenase Involved in ferulic acid and sinapic acid biosynthesis by oxidation of conyferylaldehyde and sinapaldehyde%2C respectively. Can oxidize L-lactaldehyde. Possesses activity on acetaldehyde and glycolaldehyde in vitro%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL03906 aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02235 BL14DL4_02236 BL14DL4_02236 BL14DL4_02236 2067124 2067903 + Glycerol operon regulatory protein May be an activator protein for the gylABX operon. Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02236 BL14DL4_02237 BL14DL4_02237 BL14DL4_02237 2067922 2068872 + 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA)%2C a key precursor of NAD%2C and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD%2C ACMS is converted to AMS%2C a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway (By similarity)%3B Belongs to the ACMSD family gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02237 BL14DL4_02238 BL14DL4_02238 BL14DL4_02238 2068916 2069887 - Phosphate acetyltransferase Belongs to the phosphate acetyltransferase and butyryltransferase family%3B KEGG: bsu:BSU37660 phosphate acetyltransferase gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02238 BL14DL4_02239 BL14DL4_02239 BL14DL4_02239 2070177 2070941 + Chlorite O(2)-lyase May function as heme-dependent peroxidase%3B Belongs to the UPF0447 family%3B KEGG: bsr:I33_3915 chlorite dismutase gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02239 BL14DL4_02240 BL14DL4_02240 BL14DL4_02240 2070990 2071532 - uncharacterized protein Required for complex colony architecture gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02240 BL14DL4_02241 BL14DL4_02241 BL14DL4_02241 2071949 2073295 + Ktr system potassium uptake protein Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the TrkH potassium transport family. Ktr (TC 2. A. 38. 4) subfamily gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02241 BL14DL4_02242 BL14DL4_02242 BL14DL4_02242 2073532 2074059 + Spore coat protein GerQ Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02242 BL14DL4_02243 BL14DL4_02243 BL14DL4_02243 2074100 2075245 - Putative transport permease YfiN Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02243 BL14DL4_02244 BL14DL4_02244 BL14DL4_02244 2075247 2076368 - hypothetical protein gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02244 BL14DL4_02245 BL14DL4_02245 potA potA 2076385 2077320 - Polyamine-transporting ATPase Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: rme:Rmet_4399 spermidine/putrescine transport system ATP-binding protein gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02245 BL14DL4_02246 BL14DL4_02246 BL14DL4_02246 2077424 2078530 - Sensor histidine kinase YfiJ Member of the two-component regulatory system YfiJ/YfiK. Probably activates YfiK by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bcz:BCZK1607 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02246 BL14DL4_02247 BL14DL4_02247 cheB cheB 2078545 2079216 - Protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain%3B KEGG: tbe:Trebr_0103 two-component system%2C chemotaxis family%2C response regulator CheB gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02247 BL14DL4_02248 BL14DL4_02248 parS parS 2079343 2079720 - Proline--tRNA ligase Belongs to the UPF0382 family%3B KEGG: gsl:Gasu_24190 prolyl-tRNA synthetase gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02248 BL14DL4_02249 BL14DL4_02249 BL14DL4_02249 2079782 2081083 - Putative purine permease YwdJ Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02249 BL14DL4_02250 BL14DL4_02250 BL14DL4_02250 2081123 2081431 - uncharacterized protein gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02250 BL14DL4_02251 BL14DL4_02251 BL14DL4_02251 2081703 2083085 + Aldehyde dehydrogenase (NAD(+)) ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids%2C biogenic amines%2C neurotransmitters%2C and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes (By similarity)%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL03952 aldehyde dehydrogenase (NAD+) gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02251 BL14DL4_02252 BL14DL4_02252 BL14DL4_02252 2083133 2083810 - Uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine%3B Belongs to the uracil-DNA glycosylase family%3B KEGG: bsu:BSU37970 uracil-DNA glycosylase gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02252 BL14DL4_02253 BL14DL4_02253 BL14DL4_02253 2083824 2084642 - putative glycosyltransferase YwdF Belongs to the glycosyltransferase 2 family gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02253 BL14DL4_02254 BL14DL4_02254 pdxK pdxK 2084880 2085692 + Pyridoxal kinase Phosphorylates B6 vitamer%3B functions in a salvage pathway. Uses pyridoxal%2C pyridoxine%2C and pyridoxamine as substrates. Can also use hydroxymethylpyrimidine (HMP) as substrate%3B Belongs to the ThiD family%3B KEGG: bsu:BSU38020 pyridoxine kinase gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02254 BL14DL4_02255 BL14DL4_02255 BL14DL4_02255 2085726 2086064 - hypothetical protein gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02255 BL14DL4_02256 BL14DL4_02256 sacA sacA 2086081 2087517 - Beta-fructofuranosidase Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL03892 beta-fructofuranosidase gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02256 BL14DL4_02257 BL14DL4_02257 scrA scrA 2087535 2088914 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in sucrose transport (By similarity)%3B Acts as both a kinase and a phosphatase on SacT%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL03890 PTS system%2C sucrose-specific IIB component gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02257 BL14DL4_02258 BL14DL4_02258 BL14DL4_02258 2089160 2089999 - SacPA operon antiterminator Mediates positive regulation of the sacPA operon by functioning as an antiterminator factor of transcription. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02258 BL14DL4_02259 BL14DL4_02259 BL14DL4_02259 2090033 2090323 - hypothetical protein gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02259 BL14DL4_02260 BL14DL4_02260 BL14DL4_02260 2090475 2090687 + hypothetical protein gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02260 BL14DL4_02261 BL14DL4_02261 BL14DL4_02261 2090804 2093224 + Minor extracellular protease vpr Not required for growth or sporulation. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL03950 minor extracellular serine protease Vpr%3B Serine endopeptidases gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02261 BL14DL4_02262 BL14DL4_02262 BL14DL4_02262 2093348 2093596 + hypothetical protein gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02262 BL14DL4_02263 BL14DL4_02263 BL14DL4_02263 2093593 2094600 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02263 BL14DL4_02264 BL14DL4_02264 BL14DL4_02264 2094687 2094824 + hypothetical protein gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02264 BL14DL4_02265 BL14DL4_02265 BL14DL4_02265 2094853 2095602 - FMN reductase (NADPH) Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Belongs to the flavin oxidoreductase frp family%3B KEGG: bli:BL03887 FMN reductase (NADPH) gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02265 BL14DL4_02266 BL14DL4_02266 hipO hipO 2095747 2096922 + Hippurate hydrolase Belongs to the peptidase M20A family%3B KEGG: brh:RBRH_03274 hippurate hydrolase gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02266 BL14DL4_02267 BL14DL4_02267 BL14DL4_02267 2096950 2098119 - Rod shape-determining protein RodA Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02267 BL14DL4_02268 BL14DL4_02268 BL14DL4_02268 2098231 2099415 - Rod shape-determining protein RodA Required for the maintenance of the rod cell shape. Also essential for the elongation of the lateral wall of the cell%3B Belongs to the SEDS family. RodA subfamily gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02268 BL14DL4_02269 BL14DL4_02269 BL14DL4_02269 2099694 2101049 + uncharacterized protein gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02269 BL14DL4_02270 BL14DL4_02270 BL14DL4_02270 2101039 2101221 - hypothetical protein gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02270 BL14DL4_02271 BL14DL4_02271 BL14DL4_02271 2101473 2101733 + Spore morphoproteinis and germination protein YwcE Required for proper spore morphogenesis. Important for spore germination (By similarity)%3B Belongs to the YwcE family gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02271 BL14DL4_02272 BL14DL4_02272 BL14DL4_02272 2101781 2102980 - hypothetical protein gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02272 BL14DL4_02273 BL14DL4_02273 BL14DL4_02273 2102998 2103453 - putative N-acetyltransferase YfmK Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02273 BL14DL4_02274 BL14DL4_02274 BL14DL4_02274 2103465 2105273 - ABC transporter B family member 23%2C mitochondrial Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Not involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria into the cytosol%3B Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3. A. 1. 210) subfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02274 BL14DL4_02275 BL14DL4_02275 BL14DL4_02275 2105267 2107216 - putative anion import ATP-binding protein Part of an ABC transporter complex involved in anions import (Probable). Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02275 BL14DL4_02276 BL14DL4_02276 BL14DL4_02276 2107235 2109235 - Asparagine synthase (glutamine-hydrolyzing) KEGG: blh:BaLi_c40470 asparagine synthase (glutamine-hydrolysing) gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02276 BL14DL4_02277 BL14DL4_02277 BL14DL4_02277 2109232 2109696 - hypothetical protein gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02277 BL14DL4_02278 BL14DL4_02278 BL14DL4_02278 2109696 2109968 - hypothetical protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02278 BL14DL4_02279 BL14DL4_02279 BL14DL4_02279 2110319 2110951 - Response regulator GacA Involved in the regulation of secondary metabolism. Involved in the synthesis of the antifungal factors cyanide and 2%2C4-diacetylphloroglucinol. Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02279 BL14DL4_02280 BL14DL4_02280 BL14DL4_02280 2111123 2111239 + hypothetical protein gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02280 BL14DL4_02281 BL14DL4_02281 qoxD qoxD 2111294 2111659 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bli:BL03874 cytochrome aa3-600 menaquinol oxidase subunit IV gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02281 BL14DL4_02282 BL14DL4_02282 qoxC qoxC 2111659 2112273 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bli:BL03873 cytochrome aa3-600 menaquinol oxidase subunit III gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02282 BL14DL4_02283 BL14DL4_02283 qoxB qoxB 2112288 2114237 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL03872 cytochrome aa3-600 menaquinol oxidase subunit I gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02283 BL14DL4_02284 BL14DL4_02284 qoxA qoxA 2114255 2115223 - Menaquinol oxidase (H(+)-transporting) Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Major component for energy conversion during vegetative growth. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I. Belongs to the cytochrome c oxidase subunit 2 family%3B KEGG: bld:BLi04040 cytochrome aa3-600 menaquinol oxidase subunit II gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02284 BL14DL4_02285 BL14DL4_02285 BL14DL4_02285 2115695 2116684 - UDP-glucose 4-epimerase Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: ecl:EcolC_3183 UDP-glucose 4-epimerase gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02285 BL14DL4_02286 BL14DL4_02286 BL14DL4_02286 2117487 2117636 + hypothetical protein gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02286 BL14DL4_02287 BL14DL4_02287 BL14DL4_02287 2117807 2118025 - hypothetical protein gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02287 BL14DL4_02288 BL14DL4_02288 BL14DL4_02288 2118178 2118417 + Putative NAD(P)H-dependent FMN-containing oxidoreductase YwqN Putative NADPH-dependent oxidoreductase%3B Belongs to the SsuE family gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02288 BL14DL4_02289 BL14DL4_02289 BL14DL4_02289 2118436 2118747 + Putative NAD(P)H-dependent FMN-containing oxidoreductase YwqN Putative NADPH-dependent oxidoreductase%3B Belongs to the SsuE family gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02289 BL14DL4_02290 BL14DL4_02290 BL14DL4_02290 2118916 2119230 + uncharacterized protein gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02290 BL14DL4_02291 BL14DL4_02291 BL14DL4_02291 2119227 2120765 + putative symporter YwcA Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02291 BL14DL4_02292 BL14DL4_02292 xylB xylB 2120818 2122317 - Xylulokinase Belongs to the FGGY kinase family%3B KEGG: sod:Sant_1620 xylulokinase gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02292 BL14DL4_02293 BL14DL4_02293 xylA xylA 2122317 2123663 - Xylose isomerase Belongs to the xylose isomerase family%3B KEGG: bli:BL03867 xylose isomerase gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02293 BL14DL4_02294 BL14DL4_02294 BL14DL4_02294 2123855 2125018 + Xylose repressor Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02294 BL14DL4_02295 BL14DL4_02295 BL14DL4_02295 2125259 2125933 - Thiamine phosphate synthase Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)%3B Belongs to the thiamine-phosphate synthase family%3B KEGG: bli:BL03866 thiamine-phosphate pyrophosphorylase gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02295 BL14DL4_02296 BL14DL4_02296 thiM thiM 2125935 2126744 - Hydroxyethylthiazole kinase Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)%3B Belongs to the Thz kinase family%3B KEGG: bli:BL03865 hydroxyethylthiazole kinase gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02296 BL14DL4_02297 BL14DL4_02297 BL14DL4_02297 2126741 2127658 - putative HTH-type transcriptional regulator YwbI Contains 1 HTH lysR-type DNA-binding domain gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02297 BL14DL4_02298 BL14DL4_02298 BL14DL4_02298 2127779 2128048 - uncharacterized protein gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02298 BL14DL4_02299 BL14DL4_02299 BL14DL4_02299 2128045 2128473 - uncharacterized protein gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02299 BL14DL4_02300 BL14DL4_02300 BL14DL4_02300 2128957 2129343 + Holin-like protein CidA Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell%2C the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment%2C CidA possibly oligomerizes within the bacterial cell membrane%2C creating lesions that disrupt the proton motive force%2C which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential%3B Belongs to the CidA/LrgA family. CidA subfamily gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02300 BL14DL4_02301 BL14DL4_02301 BL14DL4_02301 2129325 2130008 + uncharacterized protein Belongs to the YohK (E. coli)/YwbG (IPA-22R) (B. subtilis) family gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02301 BL14DL4_02302 BL14DL4_02302 BL14DL4_02302 2130064 2130348 - hypothetical protein gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02302 BL14DL4_02303 BL14DL4_02303 BL14DL4_02303 2130359 2131825 - Osmoregulated proline transporter OpuE Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02303 BL14DL4_02304 BL14DL4_02304 rlmI rlmI 2131924 2133114 - 23S rRNA (cytosine(1962)-C(5))-methyltransferase Belongs to the methyltransferase superfamily. RlmI family%3B Contains 1 PUA domain%3B KEGG: bli:BL03857 23S rRNA (cytosine1962-C5)-methyltransferase gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02304 BL14DL4_02305 BL14DL4_02305 glo1 glo1 2133257 2133637 + Lactoylglutathione lyase Belongs to the glyoxalase I family%3B KEGG: bli:BL03939 lactoylglutathione lyase gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02305 BL14DL4_02306 BL14DL4_02306 BL14DL4_02306 2133668 2134615 - Phosphoglycerate dehydrogenase Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate%2C respectively%3B Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily%3B KEGG: blh:BaLi_c40720 D-3-phosphoglycerate dehydrogenase gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02306 BL14DL4_02307 BL14DL4_02307 waaJ waaJ 2134754 2135617 - Lipopolysaccharide glucosyltransferase I Belongs to the glycosyltransferase 8 family%3B KEGG: stm:STM3717 UDP-glucose:(galactosyl)LPS alpha-1%2C2-glucosyltransferase gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02307 BL14DL4_02308 BL14DL4_02308 BL14DL4_02308 2135571 2135705 - hypothetical protein gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02308 BL14DL4_02309 BL14DL4_02309 BL14DL4_02309 2135739 2135909 - putative membrane protein YdzP gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02309 BL14DL4_02310 BL14DL4_02310 ydfH ydfH 2136413 2137576 + Histidine kinase Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bsu:BSU05410 two-component system%2C NarL family%2C sensor histidine kinase YdfH gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02310 BL14DL4_02311 BL14DL4_02311 BL14DL4_02311 2137569 2138207 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02311 BL14DL4_02312 BL14DL4_02312 BL14DL4_02312 2138324 2140498 + Membrane protein YdfJ Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02312 BL14DL4_02313 BL14DL4_02313 BL14DL4_02313 2140595 2141335 - uncharacterized protein gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02313 BL14DL4_02314 BL14DL4_02314 BL14DL4_02314 2141430 2142761 - Inner membrane transport protein RhmT Belongs to the major facilitator superfamily. Phthalate permease family gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02314 BL14DL4_02315 BL14DL4_02315 dgoD dgoD 2142823 2143971 - Galactonate dehydratase Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily%3B KEGG: bli:BL03851 galactonate dehydratase gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02315 BL14DL4_02316 BL14DL4_02316 BL14DL4_02316 2143988 2144614 - 2-dehydro-3-deoxy-phosphogluconate aldolase Belongs to the KHG/KDPG aldolase family%3B KEGG: bli:BL03850 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02316 BL14DL4_02317 BL14DL4_02317 BL14DL4_02317 2144642 2145595 - 2-dehydro-3-deoxygluconokinase Involved in the degradation of glucose via the semi- phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2- keto-3-deoxy-6-phosphogluconate (KDPG)%3B Belongs to the carbohydrate kinase pfkB family%3B KEGG: efe:EFER_3552 2-dehydro-3-deoxygluconokinase gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02317 BL14DL4_02318 BL14DL4_02318 BL14DL4_02318 2145613 2146371 - putative HTH-type transcriptional regulator YagI Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02318 BL14DL4_02319 BL14DL4_02319 BL14DL4_02319 2146601 2147950 + Aminopeptidase YwaD Catalyzes the hydrolysis of a range of N-terminal amino acids%3B Belongs to the peptidase M28 family. M28B subfamily%3B KEGG: bcz:BCZK5056 aminopeptidase%3B Aminopeptidases gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02319 BL14DL4_02320 BL14DL4_02320 BL14DL4_02320 2148174 2149535 - putative MFS-type transporter YwoD Belongs to the major facilitator superfamily gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02320 BL14DL4_02321 BL14DL4_02321 BL14DL4_02321 2149536 2149748 - hypothetical protein gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02321 BL14DL4_02322 BL14DL4_02322 BL14DL4_02322 2150207 2150866 - GTP diphosphokinase Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in response to changes in nutritional abundance. YwaC has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bli:BL03845 putative GTP pyrophosphokinase gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02322 BL14DL4_02323 BL14DL4_02323 BL14DL4_02323 2150957 2151118 - hypothetical protein gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02323 BL14DL4_02324 BL14DL4_02324 BL14DL4_02324 2151407 2151556 + putative membrane protein YwzH gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02324 BL14DL4_02325 BL14DL4_02325 dltA dltA 2151571 2153079 + D-alanine--poly(phosphoribitol) ligase Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp%3B Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily%3B KEGG: bli:BL03934 D-alanine--poly(phosphoribitol) ligase subunit 1 gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02325 BL14DL4_02326 BL14DL4_02326 BL14DL4_02326 2153076 2154233 + Protein DltB Could be involved in the transport of activated D- alanine through the membrane. Belongs to the membrane-bound acyltransferase family gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02326 BL14DL4_02327 BL14DL4_02327 dltC dltC 2154249 2154485 + D-alanine--poly(phosphoribitol) ligase Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA%3B Contains 1 acyl carrier domain%3B KEGG: bli:BL03932 D-alanine--poly(phosphoribitol) ligase subunit 2 gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02327 BL14DL4_02328 BL14DL4_02328 BL14DL4_02328 2154485 2155654 + Protein DltD gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02328 BL14DL4_02329 BL14DL4_02329 BL14DL4_02329 2155825 2156916 + Branched-chain-amino-acid transaminase Transaminates branched-chain amino acids and ketoglutarate%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03930 branched-chain amino acid aminotransferase gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02329 BL14DL4_02330 BL14DL4_02330 BL14DL4_02330 2157149 2158411 + putative MFS-type transporter YvqJ Belongs to the major facilitator superfamily gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02330 BL14DL4_02331 BL14DL4_02331 celF celF 2158513 2159841 - 6-phospho-beta-glucosidase Hydrolyzes phospho-beta-glucosides%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bsu:BSU38560 6-phospho-beta-glucosidase gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02331 BL14DL4_02332 BL14DL4_02332 BL14DL4_02332 2159841 2160101 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: cama:F384_22785 PTS system%2C cellobiose-specific IIA component gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02332 BL14DL4_02333 BL14DL4_02333 BL14DL4_02333 2160186 2161538 - Cellobiose permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02333 BL14DL4_02334 BL14DL4_02334 BL14DL4_02334 2161553 2161858 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: ebi:EbC_39840 PTS system%2C cellobiose-specific IIB component gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02334 BL14DL4_02335 BL14DL4_02335 BL14DL4_02335 2161985 2163934 - putative licABCH operon regulator Positive regulator of the licABCH operon. Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02335 BL14DL4_02336 BL14DL4_02336 BL14DL4_02336 2164090 2164197 - hypothetical protein gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02336 BL14DL4_02337 BL14DL4_02337 BL14DL4_02337 2164260 2164850 - DNA-3-methyladenine glycosylase II Belongs to the DNA glycosylase MPG family%3B KEGG: bli:BL05369 DNA-3-methyladenine glycosylase gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02337 BL14DL4_02338 BL14DL4_02338 BL14DL4_02338 2165057 2165728 + putative HTH-type transcriptional regulator in unstable DNA locus Contains 1 HTH gntR-type DNA-binding domain gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02338 BL14DL4_02339 BL14DL4_02339 BL14DL4_02339 2165804 2166919 + Citrate (Si)-synthase Belongs to the citrate synthase family%3B KEGG: bli:BL00561 citrate synthase gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02339 BL14DL4_02340 BL14DL4_02340 prpD prpD 2166955 2168394 + 2-methylcitrate dehydratase Component of the methylcitrate cycle that catalyzes the dehydration of 2-methylcitrate to 2-methyl-cis-aconitate. The methylcitrate cycle is a metabolic pathway for the consumption of propionic acid%3B Belongs to the PrpD family%3B KEGG: bli:BL00562 2-methylcitrate dehydratase gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02340 BL14DL4_02341 BL14DL4_02341 BL14DL4_02341 2168407 2169324 + Carboxyvinyl-carboxyphosphonate phosphorylmutase Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R%2C3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family%3B KEGG: bli:BL00563 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02341 BL14DL4_02342 BL14DL4_02342 BL14DL4_02342 2169367 2170560 - putative chromate transport protein May function in the active transport of chromate into the cell under sulfur-deficient conditions. Belongs to the chromate ion transporter (CHR) (TC 2. A. 51) family gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02342 BL14DL4_02343 BL14DL4_02343 BL14DL4_02343 2170573 2171004 - hypothetical protein gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02343 BL14DL4_02344 BL14DL4_02344 BL14DL4_02344 2171027 2172742 - putative ABC transporter ATP-binding protein YwjA Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02344 BL14DL4_02345 BL14DL4_02345 BL14DL4_02345 2172857 2173516 - Rhamnogalacturonan acetylesterase RhgT May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02345 BL14DL4_02346 BL14DL4_02346 BL14DL4_02346 2173834 2174418 + uncharacterized protein To B. subtilis YuaB gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02346 BL14DL4_02347 BL14DL4_02347 BL14DL4_02347 2174646 2175119 + uncharacterized protein Required for complex colony architecture gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02347 BL14DL4_02348 BL14DL4_02348 BL14DL4_02348 2175160 2176389 - Multidrug resistance protein Multidrug resistance pump that participates in a low energy shock adaptive response. Belongs to the major facilitator superfamily gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02348 BL14DL4_02349 BL14DL4_02349 BL14DL4_02349 2176499 2177275 - putative transmembrane protein YxlG gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02349 BL14DL4_02350 BL14DL4_02350 BL14DL4_02350 2177272 2178159 - Putative phosphonates utilization ATP-binding protein Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02350 BL14DL4_02351 BL14DL4_02351 BL14DL4_02351 2178159 2178371 - Negative regulatory protein YxlE Together with YxlD is important for negative regulation of sigma Y activity gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02351 BL14DL4_02352 BL14DL4_02352 BL14DL4_02352 2178368 2178586 - Negative regulatory protein YxlD Together with YxlE%2C is important for negative regulation of sigma Y activity%2C being the major negative regulator gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02352 BL14DL4_02353 BL14DL4_02353 BL14DL4_02353 2178587 2178910 - uncharacterized protein gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02353 BL14DL4_02354 BL14DL4_02354 BL14DL4_02354 2178907 2179533 - ECF RNA polymerase sigma factor SigW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02354 BL14DL4_02355 BL14DL4_02355 BL14DL4_02355 2179594 2180847 + putative MFS-type transporter YxlH Belongs to the major facilitator superfamily. TCR/Tet family gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02355 BL14DL4_02356 BL14DL4_02356 katE katE 2180891 2182489 - Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bli:BL00939 catalase gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02356 BL14DL4_02357 BL14DL4_02357 BL14DL4_02357 2182676 2184133 + Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family%3B KEGG: bli:BL00951 catalase gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02357 BL14DL4_02358 BL14DL4_02358 BL14DL4_02358 2184251 2184667 + Peroxide operon regulator Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02358 BL14DL4_02359 BL14DL4_02359 hemH hemH 2184674 2185627 + Protoporphyrin ferrochelatase Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bsu:BSU10130 ferrochelatase gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02359 BL14DL4_02360 BL14DL4_02360 BL14DL4_02360 2185654 2186595 - uncharacterized protein gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02360 BL14DL4_02361 BL14DL4_02361 BL14DL4_02361 2186601 2187503 - Ribose import ATP-binding protein RbsA Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Ribose importer (TC 3. A. 1. 2. 1) family%3B Contains 2 ABC transporter domains gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02361 BL14DL4_02362 BL14DL4_02362 BL14DL4_02362 2187484 2188233 - hypothetical protein gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02362 BL14DL4_02363 BL14DL4_02363 BL14DL4_02363 2188187 2188900 - hypothetical protein gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02363 BL14DL4_02364 BL14DL4_02364 BL14DL4_02364 2188887 2189522 - Sulfate/thiosulfate import ATP-binding protein CysA Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3. A. 1. 6) family%3B Contains 1 ABC transporter domain gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02364 BL14DL4_02365 BL14DL4_02365 BL14DL4_02365 2189525 2189812 - hypothetical protein gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02365 BL14DL4_02366 BL14DL4_02366 BL14DL4_02366 2189812 2190051 - putative HTH-type transcriptional regulator Contains 1 HTH cro/C1-type DNA-binding domain gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02366 BL14DL4_02367 BL14DL4_02367 BL14DL4_02367 2190200 2190388 - hypothetical protein gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02367 BL14DL4_02368 BL14DL4_02368 BL14DL4_02368 2190394 2191725 - hypothetical protein gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02368 BL14DL4_02369 BL14DL4_02369 BL14DL4_02369 2191722 2193815 - Lacticin-481/lactococcin-DR transport/processing ATP-binding protein lcnDR3 Probably implicated in the export process of the lantibiotic lacticin-481/lactococcin-DR. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B Contains 1 peptidase C39 domain gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02369 BL14DL4_02370 BL14DL4_02370 BL14DL4_02370 2193887 2196997 - Lacticin 481/lactococcin biosynthesis protein lcnDR2 gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02370 BL14DL4_02371 BL14DL4_02371 BL14DL4_02371 2197048 2197266 - Lantibiotic lichenicidin VK21 A2 Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes%2C initiated by the formation of aqueous transmembrane pores. When present individually%2C LchA2 exhibits activity towards B. subtilis L1 (IC(50)%3D30 uM)%2C Rhodococcus sp. SS2 (IC(50)%3D16. 6 uM)%2C M. luteus B1314 (IC(50)%3D2. 6 uM)%2C B. megaterium VKM41 (IC(50)%3D2 uM)%2C S. aureus 209p (IC(50)%3D20 uM)%2C B. pumilus 2001%2C B. globigii I%2C B. amyloliquefaciens I%2C M. smegmatis 1171 and M. phlei 1291. However%2C when combined with LchA1%2C it displays much stronger activty against B. subtilis L1 (IC(50)%3D0. 64 uM)%2C Rhodococcus sp. SS2 (IC(50)%3D0. 64 uM)%2C M. luteus B1314 (IC(50)%3D0. 09 uM)%2C B. megaterium VKM41 (IC(50)%3D0. 12 uM) and S. aureus 209p (IC(50)%3D0. 64 uM). The activity of the combined LchA1 and LchA2 peptides is strongest at a molar ratio of 1. Even when applied at 17-fold concentration of the highest IC(50) values for Gram-positive bacteria%2C neither the individual nor the combined peptides display activity against Gram-negative bacteria P. aeruginosa PAO1%2C P. putida I-97 or E. coli C600 gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02371 BL14DL4_02372 BL14DL4_02372 BL14DL4_02372 2197404 2197628 + Lantibiotic lichenicidin Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes%2C initiated by the formation of aqueous transmembrane pores. When present individually%2C LchA1 exhibits activity towards L. lactis HP. When combined with LchA2%2C it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L. monocytogenes%2C methicillin-resistant S. aureus%2C S. pneumoniae and strains of vancomycin-resistant enterococci%2C but not towards E. faecium L4001 and BM4147-1. Combined LchA1 and LchA2 peptides also inhibit Bacillus sp. HIL-Y85/54728%2C L. lactis DPC3417 and B. halodurans C-125%2C which produce lantibiotics themselves. Inactivated by proteinase K and pronase E%2C but not by trypsin and chymotrypsin gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02372 BL14DL4_02373 BL14DL4_02373 BL14DL4_02373 2197690 2200848 + Lacticin 481/lactococcin biosynthesis protein lcnDR2 gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02373 BL14DL4_02374 BL14DL4_02374 BL14DL4_02374 2201139 2202164 + Pectate lyase Cleaves unsaturated oligo-galacturonides from pectin. The major product is trigalacturonat%3B digalacturonate and tetragalacturonate are also produced. Activity on methylated pectins decreases with an increasing degree of methylation (By similarity)%3B Belongs to the polysaccharide lyase 1 family%3B Contains 4 PbH1 repeats%3B KEGG: blh:BaLi_c41260 pectate lyase gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02374 BL14DL4_02375 BL14DL4_02375 BL14DL4_02375 2202201 2203052 - ADP-dependent NAD(P)H-hydrate dehydratase Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP%2C which is converted to AMP. This allows the repair of both epimers of NAD(P)HX%2C a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)%3B In the N-terminal sectio%3B belongs to the NnrE/AIBP family%3B In the C-terminal sectio%3B belongs to the NnrD/CARKD family%3B Contains 1 YjeF C-terminal domain%3B Contains 1 YjeF N-terminal domain%3B KEGG: bli:BL00927 ADP-dependent NAD(P)H-hydrate dehydratase gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02375 BL14DL4_02376 BL14DL4_02376 BL14DL4_02376 2203221 2204969 - ATP-binding/permease protein CydD Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02376 BL14DL4_02377 BL14DL4_02377 BL14DL4_02377 2204966 2206690 - ATP-binding/permease protein CydC Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02377 BL14DL4_02378 BL14DL4_02378 BL14DL4_02378 2206690 2207706 - Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 2 family%3B KEGG: bli:BL00924 cytochrome d ubiquinol oxidase subunit II%3B With oxygen as acceptor gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02378 BL14DL4_02379 BL14DL4_02379 BL14DL4_02379 2207693 2209099 - Cytochrome bd ubiquinol oxidase subunit Belongs to the cytochrome ubiquinol oxidase subunit 1 family%3B KEGG: gbm:Gbem_2016 cytochrome d ubiquinol oxidase subunit I%3B With oxygen as acceptor gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02379 BL14DL4_02380 BL14DL4_02380 BL14DL4_02380 2209898 2210686 + putative transporter YwcJ Belongs to the FNT transporter (TC 2. A. 44) family gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02380 BL14DL4_02381 BL14DL4_02381 BL14DL4_02381 2210831 2211160 + hypothetical protein gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02381 BL14DL4_02382 BL14DL4_02382 BL14DL4_02382 2211178 2212509 - Malate dehydrogenase (oxaloacetate-decarboxylating) Belongs to the malic enzymes family%3B Contains 1 ACT domain%3B KEGG: bli:BL00922 malate dehydrogenase (oxaloacetate-decarboxylating) gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02382 BL14DL4_02383 BL14DL4_02383 BL14DL4_02383 2212544 2213941 - Malate-2H(+)/Na(+)-lactate antiporter Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02383 BL14DL4_02384 BL14DL4_02384 aspA aspA 2214184 2215611 - Aspartate ammonia-lyase Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bli:BL05376 aspartate ammonia-lyase gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02384 BL14DL4_02385 BL14DL4_02385 BL14DL4_02385 2215632 2216621 - Asparaginase Belongs to the asparaginase 1 family%3B Contains 1 asparaginase/glutaminase domain%3B KEGG: bsu:BSU23580 L-asparaginase gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02385 BL14DL4_02386 BL14DL4_02386 BL14DL4_02386 2216837 2217184 + HTH-type transcriptional regulator AnsR Transcriptional repressor for the ans operon coding for L-asparaginase and L-aspartase. NH4(+) may influence this repression. Contains 1 HTH cro/C1-type DNA-binding domain gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02386 BL14DL4_02387 BL14DL4_02387 BL14DL4_02387 2217265 2218311 - 6-phosphogluconolactonase Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate%3B Belongs to the cycloisomerase 2 family%3B KEGG: bli:BL02413 6-phosphogluconolactonase gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02387 BL14DL4_02388 BL14DL4_02388 BL14DL4_02388 2218508 2219197 + Response regulator ArlR Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02388 BL14DL4_02389 BL14DL4_02389 yxdK yxdK 2219194 2220174 + Histidine kinase Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL02955 two-component system%2C OmpR family%2C sensor histidine kinase YxdK gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02389 BL14DL4_02390 BL14DL4_02390 BL14DL4_02390 2220457 2221233 + Methionine import ATP-binding protein MetN Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02390 BL14DL4_02391 BL14DL4_02391 BL14DL4_02391 2221208 2223085 + ABC transporter permease protein YxdM Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02391 BL14DL4_02392 BL14DL4_02392 BL14DL4_02392 2223092 2223442 + uncharacterized protein gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02392 BL14DL4_02393 BL14DL4_02393 BL14DL4_02393 2223558 2223731 + hypothetical protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02393 BL14DL4_02394 BL14DL4_02394 BL14DL4_02394 2224047 2224298 + hypothetical protein gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02394 BL14DL4_02395 BL14DL4_02395 pgaB pgaB 2224331 2225170 - Putative polysaccharide deacetylase YxkH Belongs to the polysaccharide deacetylase family%3B KEGG: bbe:BBR47_54040 biofilm PGA synthesis lipoprotein PgaB%3B Hydrolases gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02395 BL14DL4_02396 BL14DL4_02396 BL14DL4_02396 2225231 2226127 - HTH-type transcriptional regulatory protein GabR Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02396 BL14DL4_02397 BL14DL4_02397 bcsA bcsA 2226268 2228526 - Cellulose synthase (UDP-forming) In the N-terminal sectio%3B belongs to the glycosyltransferase 2 family%3B In the C-terminal sectio%3B belongs to the AcsB/BcsB family%3B Contains 1 PilZ domain%3B KEGG: bpu:BPUM_3398 cellulose synthase (UDP-forming) gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02397 BL14DL4_02398 BL14DL4_02398 BL14DL4_02398 2229121 2230473 + Citrate/malate transporter Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporte%3B the number of protons transported is equal to the valence of the transported anions. Is strictly stereoselective%2C translocating only the (S)-enantiomer of malate. Belongs to the sodium:citrate (SCF) symporter family gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02398 BL14DL4_02399 BL14DL4_02399 BL14DL4_02399 2230520 2231380 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bli:BL02963 glycerophosphoryl diester phosphodiesterase gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02399 BL14DL4_02400 BL14DL4_02400 BL14DL4_02400 2231521 2231790 - uncharacterized protein gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02400 BL14DL4_02401 BL14DL4_02401 BL14DL4_02401 2231932 2232591 - hypothetical protein gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02401 BL14DL4_02402 BL14DL4_02402 BL14DL4_02402 2232711 2234630 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bli:BL02415 lipoteichoic acid synthase gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02402 BL14DL4_02403 BL14DL4_02403 BL14DL4_02403 2234902 2235459 - uncharacterized protein To B. subtilis YfjD gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02403 BL14DL4_02404 BL14DL4_02404 BL14DL4_02404 2235632 2236468 - UPF0750 membrane protein YxkD Belongs to the UPF0750 family gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02404 BL14DL4_02405 BL14DL4_02405 BL14DL4_02405 2236830 2237270 + Arginine regulator Regulates the transcription of the arc operon%2C involved in arginine catabolism%3B Belongs to the ArgR family gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02405 BL14DL4_02406 BL14DL4_02406 arcA arcA 2237538 2238773 + Arginine deiminase Belongs to the arginine deiminase family%3B KEGG: bli:BL01912 arginine deiminase gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02406 BL14DL4_02407 BL14DL4_02407 argF argF 2238802 2239809 + Ornithine carbamoyltransferase Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bli:BL01914 ornithine carbamoyltransferase gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02407 BL14DL4_02408 BL14DL4_02408 BL14DL4_02408 2239863 2241269 + Putative amino-acid transporter Could be an amino acid transporter. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02408 BL14DL4_02409 BL14DL4_02409 arcC arcC 2241291 2242241 + Carbamate kinase Belongs to the carbamate kinase family%3B KEGG: bli:BL01916 carbamate kinase gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02409 BL14DL4_02410 BL14DL4_02410 BL14DL4_02410 2242351 2243028 + CRP-like cAMP-activated global transcriptional regulator Global transcriptional regulator that complexes with cAMP and binds to specific DNA promoter sites%2C causing DNA- bending%2C to regulate transcription. cAMP improves binding to specific DNA sequences%2C probably by altering protein conformation. Involved in the regulation of gntP and gntK genes%2C which are involved in gluconate metabolism (PubMed:16385030). May form dimers which bind to the aceB promoter region in the presence of cAMP and repress the glyoxylate bypass genes (PubMed:15150232). It could be a positive regulator of rpf2 gene expression during growth on acetate as the sole carbon source%2C however because the cytosolic cAMP level is elevated in the presence of glucose and low upon growth on acetate%2C it is conceivable that it is unable to function as an activator under acetate conditions (PubMed:18355281)%3B Contains 1 cyclic nucleotide-binding domain%3B Contains 1 HTH crp-type DNA-binding domain gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02410 BL14DL4_02411 BL14DL4_02411 bglB bglB 2243080 2244522 - Beta-glucosidase Belongs to the glycosyl hydrolase 1 family%3B KEGG: enc:ECL_04162 beta-glucosidase gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02411 BL14DL4_02412 BL14DL4_02412 BL14DL4_02412 2244540 2245859 - Oligo-beta-mannoside permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose (Probable)%3B Contains 1 PTS EIIC type-3 domain gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02412 BL14DL4_02413 BL14DL4_02413 BL14DL4_02413 2246017 2247408 - hypothetical protein gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02413 BL14DL4_02414 BL14DL4_02414 BL14DL4_02414 2247378 2247926 - RNA polymerase sigma factor SigV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02414 BL14DL4_02415 BL14DL4_02415 BL14DL4_02415 2248042 2248455 - uncharacterized protein gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02415 BL14DL4_02416 BL14DL4_02416 pepT pepT 2248595 2249827 + Tripeptide aminopeptidase Cleaves the N-terminal amino acid of tripeptides%3B Belongs to the peptidase M20B family%3B KEGG: smaf:D781_1854 tripeptide aminopeptidase gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02416 BL14DL4_02417 BL14DL4_02417 BL14DL4_02417 2249985 2251463 - Beta-fructofuranosidase Exo-fructosidase that can hydrolyze both levan and inulin%2C leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose%2C but not melezitose%2C stachylose%2C cellobiose%2C maltose%2C and lactose%3B Belongs to the glycosyl hydrolase 32 family%3B KEGG: bli:BL01929 beta-fructofuranosidase gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02417 BL14DL4_02418 BL14DL4_02418 BL14DL4_02418 2251478 2252713 - Sucrose transport protein Proton symport transport system. Has an essential role in sucrose metabolism. Belongs to the LacY/RafB permease family gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02418 BL14DL4_02419 BL14DL4_02419 BL14DL4_02419 2253152 2254126 + Catabolite control protein Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02419 BL14DL4_02420 BL14DL4_02420 BL14DL4_02420 2254315 2254839 + hypothetical protein gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02420 BL14DL4_02421 BL14DL4_02421 BL14DL4_02421 2254938 2255621 - uncharacterized protein gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02421 BL14DL4_02422 BL14DL4_02422 BL14DL4_02422 2255648 2255809 - hypothetical protein gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02422 BL14DL4_02423 BL14DL4_02423 metE metE 2256124 2257254 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase To B. subtilis YxjH%3B KEGG: tmn:UCRPA7_3279 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02423 BL14DL4_02424 BL14DL4_02424 BL14DL4_02424 2257393 2259627 + Putative mannosyltransferase YkcB Belongs to the glycosyltransferase 39 family gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02424 BL14DL4_02425 BL14DL4_02425 BL14DL4_02425 2259627 2260625 + Dolichyl-phosphate beta-D-mannosyltransferase Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: bld:BLi04189 dolichol-phosphate mannosyltransferase gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02425 BL14DL4_02426 BL14DL4_02426 BL14DL4_02426 2260650 2261645 + UDP-glucose 4-epimerase Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: yep:YE105_C1183 UDP-glucose 4-epimerase gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02426 BL14DL4_02427 BL14DL4_02427 BL14DL4_02427 2261850 2262989 - hypothetical protein gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02427 BL14DL4_02428 BL14DL4_02428 BL14DL4_02428 2263000 2264430 - hypothetical protein gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02428 BL14DL4_02429 BL14DL4_02429 BL14DL4_02429 2264449 2265087 - hypothetical protein gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02429 BL14DL4_02430 BL14DL4_02430 BL14DL4_02430 2265090 2265386 - hypothetical protein gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02430 BL14DL4_02431 BL14DL4_02431 BL14DL4_02431 2266149 2267342 + Pyrimidine nucleoside transport protein Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02431 BL14DL4_02432 BL14DL4_02432 BL14DL4_02432 2267388 2269469 - Catalase Decomposes hydrogen peroxide into water and oxyge%3B serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation. Belongs to the catalase family. HPII subfamily%3B KEGG: blh:BaLi_c41890 catalase gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02432 BL14DL4_02433 BL14DL4_02433 BL14DL4_02433 2269605 2270081 - hypothetical protein gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02433 BL14DL4_02434 BL14DL4_02434 BL14DL4_02434 2270225 2271643 - 6-phospho-beta-glucosidase BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis. Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL01946 6-phospho-beta-glucosidase gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02434 BL14DL4_02435 BL14DL4_02435 bglF bglF 2271633 2273492 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL01947 PTS system%2C beta-glucosides-specific IIA component gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02435 BL14DL4_02436 BL14DL4_02436 BL14DL4_02436 2273902 2274636 - Beta-glucoside operon antiterminator Mediates the positive regulation of the beta-glucoside (arb) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon (By similarity)%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02436 BL14DL4_02437 BL14DL4_02437 BL14DL4_02437 2274831 2275565 - Putative HMP/thiamine permease protein YkoC Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the CbiQ family gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02437 BL14DL4_02438 BL14DL4_02438 BL14DL4_02438 2275562 2277154 - Putative ABC transporter ATP-binding protein Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains%3B KEGG: bli:BL02650 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02438 BL14DL4_02439 BL14DL4_02439 BL14DL4_02439 2277129 2277728 - Putative HMP/thiamine permease protein YkoE Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable) gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02439 BL14DL4_02440 BL14DL4_02440 tenA tenA 2277725 2278411 - Aminopyrimidine aminohydrolase Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). Is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity may not be physiologically relevant. Therefore%2C is probably involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bli:BL02647 thiaminase (transcriptional activator TenA) gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02440 BL14DL4_02441 BL14DL4_02441 BL14DL4_02441 2278830 2278988 + hypothetical protein gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02441 BL14DL4_02442 BL14DL4_02442 aceA aceA 2279040 2280311 - Isocitrate lyase Involved in the persistence and virulence of Mycobacterium. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate%2C a key step of the glyoxylate cycle%2C which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates%3B Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family%3B KEGG: bli:BL02646 isocitrate lyase gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02442 BL14DL4_02443 BL14DL4_02443 aceB aceB 2280326 2281915 - Malate synthase Belongs to the malate synthase family%3B KEGG: bli:BL02644 malate synthase gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02443 BL14DL4_02444 BL14DL4_02444 BL14DL4_02444 2281958 2282095 - hypothetical protein gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02444 BL14DL4_02445 BL14DL4_02445 arnT arnT 2282300 2284396 + Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase Belongs to the glycosyltransferase 39 family%3B KEGG: amo:Anamo_1886 4-amino-4-deoxy-L-arabinose transferase gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02445 BL14DL4_02446 BL14DL4_02446 BL14DL4_02446 2284549 2286489 - Bacitracin export permease protein BceB Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export. Belongs to the ABC-4 integral membrane protein family gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02446 BL14DL4_02447 BL14DL4_02447 msbA msbA 2286479 2287240 - Bacitracin export ATP-binding protein BceA Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: hpo:HMPREF4655_20610 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02447 BL14DL4_02448 BL14DL4_02448 bceS bceS 2287341 2288345 - Histidine kinase Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin%3B Contains 1 histidine kinase domain%3B KEGG: bss:BSUW23_14730 two-component system%2C OmpR family%2C bacitracin resistance sensor histidine kinase BceS gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02448 BL14DL4_02449 BL14DL4_02449 BL14DL4_02449 2288351 2289037 - Sensory transduction protein BceR Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS%2C binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02449 BL14DL4_02450 BL14DL4_02450 BL14DL4_02450 2289148 2290557 - 6-phospho-beta-glucosidase Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL00212 6-phospho-beta-glucosidase gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02450 BL14DL4_02451 BL14DL4_02451 BL14DL4_02451 2290598 2292442 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU39270 PTS system%2C beta-glucosides-specific IIA component gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02451 BL14DL4_02452 BL14DL4_02452 BL14DL4_02452 2292898 2293314 - uncharacterized protein gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02452 BL14DL4_02453 BL14DL4_02453 BL14DL4_02453 2293333 2294322 - Choloylglycine hydrolase Belongs to the peptidase C59 family%3B KEGG: bli:BL00216 choloylglycine hydrolase gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02453 BL14DL4_02454 BL14DL4_02454 BL14DL4_02454 2294450 2295295 - hypothetical protein gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02454 BL14DL4_02455 BL14DL4_02455 BL14DL4_02455 2295317 2296303 - hypothetical protein gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02455 BL14DL4_02456 BL14DL4_02456 BL14DL4_02456 2296518 2297945 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of the alpha-1%2C5-L-arabinan to produce arabino- oligosaccharides and L-arabinose. It is also active toward linear branched sugar beet arabinan%2C and pectin from apple%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL00219 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02456 BL14DL4_02457 BL14DL4_02457 srmB srmB 2298056 2299501 - RNA helicase ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing%2C and maintenance of genome integrity (By similarity)%3B Belongs to the DEAD box helicase family. DECD subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: pmu:PM1840 ATP-dependent RNA helicase SrmB gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02457 BL14DL4_02458 BL14DL4_02458 BL14DL4_02458 2299640 2300242 - hypothetical protein gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02458 BL14DL4_02459 BL14DL4_02459 BL14DL4_02459 2300261 2301040 - hypothetical protein gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02459 BL14DL4_02460 BL14DL4_02460 BL14DL4_02460 2301055 2302647 - Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02460 BL14DL4_02461 BL14DL4_02461 BL14DL4_02461 2302665 2302934 - hypothetical protein gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02461 BL14DL4_02462 BL14DL4_02462 BL14DL4_02462 2302944 2303336 - hypothetical protein gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02462 BL14DL4_02463 BL14DL4_02463 BL14DL4_02463 2303665 2304966 - Pyrimidine-nucleoside phosphorylase The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources%2C or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family%3B KEGG: bli:BL00227 pyrimidine-nucleoside phosphorylase gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02463 BL14DL4_02464 BL14DL4_02464 BL14DL4_02464 2304997 2306178 - Pyrimidine nucleoside transport protein Belongs to the concentrative nucleoside transporter (CNT) (TC 2. A. 41) family gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02464 BL14DL4_02465 BL14DL4_02465 BL14DL4_02465 2306260 2306931 - Deoxyribose-phosphate aldolase Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate%3B Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily%3B KEGG: bsu:BSU39420 deoxyribose-phosphate aldolase gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02465 BL14DL4_02466 BL14DL4_02466 BL14DL4_02466 2307057 2307995 - Deoxyribonucleoside regulator Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA%2C which consists of a palindrome and a direct repeat sequence located 3' to the palindrome. Belongs to the SorC transcriptional regulatory family gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02466 BL14DL4_02467 BL14DL4_02467 BL14DL4_02467 2308031 2308465 - hypothetical protein gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02467 BL14DL4_02468 BL14DL4_02468 BL14DL4_02468 2308741 2309802 + Putative lipoprotein YdaJ gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02468 BL14DL4_02469 BL14DL4_02469 BL14DL4_02469 2309783 2310634 + Diguanylate cyclase Contains 1 GGDEF domain%3B KEGG: bli:BL05221 diguanylate cyclase gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02469 BL14DL4_02470 BL14DL4_02470 BL14DL4_02470 2310624 2312354 + uncharacterized protein gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02470 BL14DL4_02471 BL14DL4_02471 mgdA mgdA 2312347 2313609 + 1%2C2-diacylglycerol 3-glucosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: synp:Syn7502_03368 1%2C2-diacylglycerol 3-beta-glucosyltransferase gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02471 BL14DL4_02472 BL14DL4_02472 BL14DL4_02472 2313567 2315741 + uncharacterized protein gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02472 BL14DL4_02473 BL14DL4_02473 avtA avtA 2315772 2317028 - Valine--pyruvate transaminase Involved in the biosynthesis of alanine%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL00232 valine--pyruvate aminotransferase gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02473 BL14DL4_02474 BL14DL4_02474 BL14DL4_02474 2317058 2318296 - hypothetical protein gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02474 BL14DL4_02475 BL14DL4_02475 BL14DL4_02475 2318293 2318859 - hypothetical protein gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02475 BL14DL4_02476 BL14DL4_02476 BL14DL4_02476 2318861 2320138 - Carnosine synthase In the C-terminal sectio%3B belongs to the lyase 1 family. Argininosuccinate lyase subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: cme:CYME_CMF080C carnosine synthase gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02476 BL14DL4_02477 BL14DL4_02477 BL14DL4_02477 2320095 2321033 - putative transporter Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02477 BL14DL4_02478 BL14DL4_02478 BL14DL4_02478 2321244 2322122 - Fructose-bisphosphate aldolase Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily%3B KEGG: bge:BC1002_3213 fructose-bisphosphate aldolase%2C class II gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02478 BL14DL4_02479 BL14DL4_02479 iolI iolI 2322144 2322980 - 2-keto-myo-inositol isomerase Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI%2C inosose or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2%2C3%2C5/4%2C6- pentahydroxycyclohexanone)%3B Belongs to the IolI family%3B KEGG: bsu:BSU39680 2-keto-myo-inositol isomerase gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02479 BL14DL4_02480 BL14DL4_02480 BL14DL4_02480 2323049 2323915 - Protein IolH gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02480 BL14DL4_02481 BL14DL4_02481 BL14DL4_02481 2323939 2324973 - Inositol 2-dehydrogenase Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: eta:ETA_32880 myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02481 BL14DL4_02482 BL14DL4_02482 BL14DL4_02482 2324998 2326302 - Minor myo-inositol transporter IolF Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02482 BL14DL4_02483 BL14DL4_02483 iolE iolE 2326315 2327217 - Myo-inosose-2 dehydratase Catalyzes the dehydration of inosose (2-keto-myo- inositol%2C 2KMI or 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone) to 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (D-2%2C3-diketo-4-deoxy-epi- inositol)%3B Belongs to the IolE/MocC family%3B KEGG: bli:BL00242 inosose dehydratase gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02483 BL14DL4_02484 BL14DL4_02484 iolD iolD 2327231 2329144 - 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) Involved in the cleavage of the C1-C2 bond of 3D- (3%2C5/4)-trihydroxycyclohexane-1%2C2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)%3B Belongs to the TPP enzyme family%3B KEGG: bsu:BSU39730 3D-(3%2C5/4)-trihydroxycyclohexane-1%2C2-dione acylhydrolase (decyclizing) gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02484 BL14DL4_02485 BL14DL4_02485 iolC iolC 2329176 2330153 - 5-dehydro-2-deoxygluconokinase Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)%3B Belongs to the carbohydrate kinase PfkB family%3B KEGG: bsu:BSU39740 5-dehydro-2-deoxygluconokinase gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02485 BL14DL4_02486 BL14DL4_02486 iolB iolB 2330181 2330996 - 5-deoxy-glucuronate isomerase Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)%3B Belongs to the isomerase IolB family%3B KEGG: bli:BL00245 5-deoxy-glucuronate isomerase gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02486 BL14DL4_02487 BL14DL4_02487 doeC doeC 2331071 2332534 - Methylmalonate semialdehyde dehydrogenase (acylating) Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA%2C respectively%3B Belongs to the aldehyde dehydrogenase family. IolA subfamily%3B KEGG: vej:VEJY3_17211 aspartate-semialdehyde dehydrogenase%3B With NAD(+) or NADP(+) as acceptor gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02487 BL14DL4_02488 BL14DL4_02488 BL14DL4_02488 2333005 2333769 + HTH-type transcriptional regulator IolR Iol operon repressor. Contains 1 HTH deoR-type DNA-binding domain gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02488 BL14DL4_02489 BL14DL4_02489 iolS iolS 2333853 2334788 + Protein IolS Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily%3B KEGG: bli:BL00183 myo-inositol catabolism protein IolS%3B With NAD(+) or NADP(+) as acceptor gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02489 BL14DL4_02490 BL14DL4_02490 BL14DL4_02490 2335044 2335937 + Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: bli:BL00184 glycerophosphoryl diester phosphodiesterase gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02490 BL14DL4_02491 BL14DL4_02491 BL14DL4_02491 2335960 2337318 + Glycerol-3-phosphate transporter Responsible for glycerol-3-phosphate uptake. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2. A. 1. 4) family gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02491 BL14DL4_02492 BL14DL4_02492 BL14DL4_02492 2337371 2339251 - Chaperone protein HtpG Molecular chaperone. Has ATPase activity%3B Belongs to the heat shock protein 90 family gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02492 BL14DL4_02493 BL14DL4_02493 BL14DL4_02493 2339612 2341213 + Putative phosphonates utilization ATP-binding protein Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: yin:CH53_3805 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02493 BL14DL4_02494 BL14DL4_02494 BL14DL4_02494 2341249 2342061 - Putative phosphatase Belongs to the HAD-like hydrolase superfamily. Cof family gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02494 BL14DL4_02495 BL14DL4_02495 BL14DL4_02495 2342218 2343267 - sn-glycerol-1-phosphate dehydrogenase Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species%3B Belongs to the glycerol-1-phosphate dehydrogenase family%3B KEGG: bli:BL00250 glycerol-1-phosphate dehydrogenase (NAD(P)+) gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02495 BL14DL4_02496 BL14DL4_02496 BL14DL4_02496 2343267 2343917 - hypothetical protein gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02496 BL14DL4_02497 BL14DL4_02497 BL14DL4_02497 2344064 2344525 - hypothetical protein gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02497 BL14DL4_02498 BL14DL4_02498 BL14DL4_02498 2344699 2345658 + Iron(3+)-hydroxamate-binding protein YxeB Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine%3B Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02498 BL14DL4_02499 BL14DL4_02499 BL14DL4_02499 2345683 2346084 - hypothetical protein gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02499 BL14DL4_02500 BL14DL4_02500 catE catE 2346290 2346658 + Catechol 2%2C3-dioxygenase KEGG: bpf:BpOF4_17485 catechol 2%2C3-dioxygenase gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02500 BL14DL4_02501 BL14DL4_02501 BL14DL4_02501 2346854 2348866 - Ferrous iron transport protein B like protein Not involved in Fe(2+) uptake but is involved in manganese uptake. Could be GTP-driven%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. FeoB GTPase (TC 9. A. 8) family%3B Contains 1 FeoB-type G (guanine nucleotide-binding) domain gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02501 BL14DL4_02502 BL14DL4_02502 BL14DL4_02502 2348863 2349090 - hypothetical protein gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02502 BL14DL4_02503 BL14DL4_02503 BL14DL4_02503 2349274 2350362 - Putative membrane-bound acyltransferase YfiQ Belongs to the acyltransferase 3 family gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02503 BL14DL4_02504 BL14DL4_02504 BL14DL4_02504 2350510 2352396 - ABC transporter permease protein YxdM Part of the ABC transporter complex YxdLM which could be involved in peptide resistance. Belongs to the ABC-4 integral membrane protein family gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02504 BL14DL4_02505 BL14DL4_02505 lolD lolD 2352371 2353135 - ATP-binding cassette sub-family A member Plays an important role in the formation of pulmonary surfactant%2C probably by transporting lipids such as cholesterol. Belongs to the ABC transporter superfamily. ABCA family%3B Contains 2 ABC transporter domains%3B KEGG: cse:Cseg_2118 lipoprotein-releasing system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02505 BL14DL4_02506 BL14DL4_02506 BL14DL4_02506 2353227 2354234 - Sensor histidine kinase YxdK Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37%3B Contains 1 histidine kinase domain%3B KEGG: ctc:CTC_p22 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02506 BL14DL4_02507 BL14DL4_02507 BL14DL4_02507 2354231 2354938 - Response regulator ArlR Member of the two-component regulatory system ArlS/ArlR%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02507 BL14DL4_02508 BL14DL4_02508 BL14DL4_02508 2355121 2355492 + hypothetical protein gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02508 BL14DL4_02509 BL14DL4_02509 BL14DL4_02509 2355521 2357206 - Putative methyl-accepting chemotaxis protein YoaH Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02509 BL14DL4_02510 BL14DL4_02510 BL14DL4_02510 2357361 2358785 - putative transporter YflA Belongs to the sodium:alanine (SAF) symporter family gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02510 BL14DL4_02511 BL14DL4_02511 BL14DL4_02511 2359099 2360229 + NAD(P)(+) transhydrogenase (Re/Si-specific) May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer%3B Belongs to the AlaDH/PNT family%3B KEGG: eco:b1603 NAD(P) transhydrogenase subunit alpha gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02511 BL14DL4_02512 BL14DL4_02512 BL14DL4_02512 2360389 2361663 - Arabinogalactan endo-beta-1%2C4-galactanase Hydrolyzes the beta-1%2C4-galactan linkages of arabinogalactan type I%2C a pectic substance found in plants such as soybeans. Belongs to the glycosyl hydrolase 53 family%3B KEGG: bli:BL00263 arabinogalactan endo-1%2C4-beta-galactosidase gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02512 BL14DL4_02513 BL14DL4_02513 bgaB bgaB 2361768 2363822 - Beta-galactosidase Hydrolyzes oligosaccharides released by the endo-1%2C4- beta-galactosidase GalA from arabinogalactan type I%2C a pectic plant polysaccharide. It is unable to use lactose as a sole carbon source (By similarity). Catalyzes the hydrolysis of lactose to its constituent monosaccharides glucose and galactose. Possesses a low level of transgalactosylation activity for the production of galacto-oligosaccharides (GOS) from lactose%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bli:BL00264 beta-galactosidase gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02513 BL14DL4_02514 BL14DL4_02514 BL14DL4_02514 2363859 2364698 - Putative arabinogalactan oligomer transport system permease protein GanQ Could be part of a binding-protein-dependent transport system for arabinogalactan oligomer%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02514 BL14DL4_02515 BL14DL4_02515 BL14DL4_02515 2364702 2365958 - Putative arabinogalactan oligomer transport system permease protein GanP Could be part of a binding-protein-dependent transport system for arabinogalactan oligomer%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02515 BL14DL4_02516 BL14DL4_02516 BL14DL4_02516 2366041 2367309 - Cyclodextrin-binding protein Binding protein for cyclodextri%3B involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha%2C beta and gamma%3B Belongs to the bacterial solute-binding protein 1 family gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02516 BL14DL4_02517 BL14DL4_02517 BL14DL4_02517 2367454 2368446 - HTH-type transcriptional regulator EbgR Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. Contains 1 HTH lacI-type DNA-binding domain gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02517 BL14DL4_02518 BL14DL4_02518 galK galK 2368702 2369871 + Galactokinase Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)%3B Belongs to the GHMP kinase family. GalK subfamily%3B KEGG: bli:BL00191 galactokinase gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02518 BL14DL4_02519 BL14DL4_02519 BL14DL4_02519 2369886 2370887 + UDP-glucose 4-epimerase Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: eal:EAKF1_ch3984 UDP-glucose 4-epimerase gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02519 BL14DL4_02520 BL14DL4_02520 galT galT 2370884 2372371 + UDP-glucose--hexose-1-phosphate uridylyltransferase Belongs to the galactose-1-phosphate uridylyltransferase type 2 family%3B KEGG: bli:BL00193 UDPglucose--hexose-1-phosphate uridylyltransferase gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02520 BL14DL4_02521 BL14DL4_02521 BL14DL4_02521 2372408 2373580 - Glucokinase Transcriptional repressor of xylose-utilizing enzymes. Belongs to the ROK (NagC/XylR) family%3B KEGG: tex:Teth514_1432 glucokinase gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02521 BL14DL4_02522 BL14DL4_02522 BL14DL4_02522 2373896 2374627 + Gluconate operon transcriptional repressor Transcriptional repressor of the gluconate operon (gntRKPZ)%2C which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operato%3B the binding is suppressed by gluconate or glucono-delta-lactone. Contains 1 HTH gntR-type DNA-binding domain gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02522 BL14DL4_02523 BL14DL4_02523 gntK gntK 2374620 2376161 + Gluconokinase Belongs to the FGGY kinase family%3B KEGG: bsu:BSU40060 gluconokinase gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02523 BL14DL4_02524 BL14DL4_02524 BL14DL4_02524 2376184 2377530 + Gluconate permease Belongs to the GntP permease family gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02524 BL14DL4_02525 BL14DL4_02525 BL14DL4_02525 2377560 2378963 + Phosphogluconate dehydrogenase (NADP(+)-dependent%2C decarboxylating) Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2)%2C with concomitant reduction of NAD to NADH. Does not contribute to oxidative pentose phosphate (PP) pathway fluxes during growth on glucose. The functional role of GntZ remains obscure%3B Belongs to the 6-phosphogluconate dehydrogenase family%3B KEGG: bsu:BSU40080 6-phosphogluconate dehydrogenase gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02525 BL14DL4_02526 BL14DL4_02526 BL14DL4_02526 2379237 2381840 + Acetaldehyde dehydrogenase (acetylating) KEGG: bli:BL00199 acetaldehyde dehydrogenase / alcohol dehydrogenase gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02526 BL14DL4_02527 BL14DL4_02527 prdX prdX 2382305 2382868 + Peroxiredoxin Directly reduces organic hydroperoxides in its reduced dithiol form. Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: ssan:NX02_24280 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02527 BL14DL4_02528 BL14DL4_02528 ahpF ahpF 2382882 2384411 + NADH dehydrogenase Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)%3B Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: meh:M301_0244 alkyl hydroperoxide reductase subunit F%3B With a disulfide as acceptor gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02528 BL14DL4_02529 BL14DL4_02529 BL14DL4_02529 2384981 2385610 - hypothetical protein gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02529 BL14DL4_02530 BL14DL4_02530 BL14DL4_02530 2385678 2386694 - hypothetical protein gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02530 BL14DL4_02531 BL14DL4_02531 BL14DL4_02531 2386879 2388522 + uncharacterized protein gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02531 BL14DL4_02532 BL14DL4_02532 BL14DL4_02532 2388513 2388830 + dCTP diphosphatase KEGG: cit:102607840 dCTP diphosphatase gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02532 BL14DL4_02533 BL14DL4_02533 BL14DL4_02533 2389112 2390008 + putative ABC transporter ATP-binding protein YvfR Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02533 BL14DL4_02534 BL14DL4_02534 BL14DL4_02534 2390010 2390558 + Putative transport permease YvfS Belongs to the ABC-2 integral membrane protein family%3B Contains 1 ABC transmembrane type-2 domain gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02534 BL14DL4_02535 BL14DL4_02535 BL14DL4_02535 2390749 2391891 + Histidine kinase Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: blh:BaLi_c43020 two-component system%2C NarL family%2C sensor histidine kinase DesK gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02535 BL14DL4_02536 BL14DL4_02536 BL14DL4_02536 2391888 2392490 + putative transcriptional regulatory protein YvfU Member of the two-component regulatory system YvfT/YvfU%3B Contains 1 HTH luxR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02536 BL14DL4_02537 BL14DL4_02537 BL14DL4_02537 2393136 2395109 - hypothetical protein gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02537 BL14DL4_02538 BL14DL4_02538 BL14DL4_02538 2395456 2395812 - hypothetical protein gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02538 BL14DL4_02539 BL14DL4_02539 BL14DL4_02539 2395809 2396504 - Manganese transport system ATP-binding protein MntB This protein is probably a component of a manganese permease%2C a binding protein-dependent%2C ATP-driven transport system. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02539 BL14DL4_02540 BL14DL4_02540 BL14DL4_02540 2397466 2397846 - hypothetical protein gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02540 BL14DL4_02541 BL14DL4_02541 BL14DL4_02541 2398627 2398788 + hypothetical protein gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02541 BL14DL4_02542 BL14DL4_02542 rlmH rlmH 2399515 2399994 - 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA%3B Belongs to the RNA methyltransferase RlmH family%3B KEGG: bli:BL02382 23S rRNA (pseudouridine1915-N3)-methyltransferase gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02542 BL14DL4_02543 BL14DL4_02543 BL14DL4_02543 2400075 2400233 - uncharacterized protein gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02543 BL14DL4_02544 BL14DL4_02544 BL14DL4_02544 2400432 2400971 - hypothetical protein gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02544 BL14DL4_02545 BL14DL4_02545 BL14DL4_02545 2401345 2401866 - Phosphinothricin acetyltransferase Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: gwc:GWCH70_2852 phosphinothricin acetyltransferase gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02545 BL14DL4_02546 BL14DL4_02546 BL14DL4_02546 2401894 2402364 - hypothetical protein gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02546 BL14DL4_02547 BL14DL4_02547 BL14DL4_02547 2402620 2403465 - Adenosyl-chloride synthase Involved in the biosynthesis of the proteosome inhibitor salinosporamide A (SalA). Catalyzes the halogenation of S- adenosyl-L-methionine (SAM) with chloride to generate 5'-chloro- 5'-deoxyadenosine (5'-CIDA) and L-methionine. It can also use bromide and iodide%2C producing halogenated 5'-deoxyadenosine (5'- XDA) and L-methionine%2C however no halogenase activity is detected in the presence of fluoride%3B Belongs to the SalL family gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02547 BL14DL4_02548 BL14DL4_02548 BL14DL4_02548 2403762 2404973 - Peptidase Do Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: afl:Aflv_2834 serine protease Do gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02548 BL14DL4_02549 BL14DL4_02549 BL14DL4_02549 2405056 2405850 - Putative metallo-hydrolase YycJ Belongs to the metallo-beta-lactamase superfamily%3B KEGG: rch:RUM_07740 ribonuclease J%3B Acting on ester bonds gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02549 BL14DL4_02550 BL14DL4_02550 BL14DL4_02550 2405865 2406713 - Two-component system YycFG regulatory protein Together with YycH%2C regulates the activity of the two- component system YycF/YycG gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02550 BL14DL4_02551 BL14DL4_02551 BL14DL4_02551 2406700 2408064 - Two-component system YycF/YycG regulatory protein YycH Together with YycI%2C regulates the activity of the two- component system YycF/YycG gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02551 BL14DL4_02552 BL14DL4_02552 vicK vicK 2408054 2409898 - Histidine kinase Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon%2C the yocH and ykvT%2C cwlO%2C lytE%2C ydjM%2C yjeA%2C yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bli:BL02372 two-component system%2C OmpR family%2C sensor histidine kinase VicK gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02552 BL14DL4_02553 BL14DL4_02553 BL14DL4_02553 2409906 2410613 - Phosphate regulon transcriptional regulatory protein This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited (By similarity)%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02553 BL14DL4_02554 BL14DL4_02554 BL14DL4_02554 2411032 2411104 - tRNA-Phe tRNA gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02554 BL14DL4_02555 BL14DL4_02555 BL14DL4_02555 2411131 2411207 - tRNA-Asp tRNA gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02555 BL14DL4_02556 BL14DL4_02556 BL14DL4_02556 2411296 2411367 - tRNA-Glu tRNA gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02556 BL14DL4_02557 BL14DL4_02557 BL14DL4_02557 2411375 2411450 - tRNA-Lys tRNA gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02557 BL14DL4_02558 BL14DL4_02558 BL14DL4_02558 2411666 2412079 - 8-oxo-dGTP diphosphatase Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: blh:BaLi_c43220 8-oxo-dGTP diphosphatase gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02558 BL14DL4_02559 BL14DL4_02559 purA purA 2412143 2413435 - Adenylosuccinate synthase Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP%3B Belongs to the adenylosuccinate synthetase family%3B KEGG: vvu:VV2_0768 adenylosuccinate synthase gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02559 BL14DL4_02560 BL14DL4_02560 BL14DL4_02560 2413700 2413966 + hypothetical protein gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02560 BL14DL4_02561 BL14DL4_02561 BL14DL4_02561 2413984 2415348 - DNA helicase Belongs to the helicase family. DnaB subfamily%3B Contains 1 SF4 helicase domain%3B KEGG: bsu:BSU40440 replicative DNA helicase gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02561 BL14DL4_02562 BL14DL4_02562 BL14DL4_02562 2415542 2415739 + uncharacterized protein gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02562 BL14DL4_02563 BL14DL4_02563 BL14DL4_02563 2415777 2415995 - hypothetical protein gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02563 BL14DL4_02564 BL14DL4_02564 BL14DL4_02564 2416138 2416275 + uncharacterized protein gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02564 BL14DL4_02565 BL14DL4_02565 BL14DL4_02565 2416346 2417551 + 2-nitroimidazole transporter Involved in efflux of 2-nitroimidazole%3B Belongs to the major facilitator superfamily. Cyanate porter (TC 2. A. 1. 17) family gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02565 BL14DL4_02566 BL14DL4_02566 BL14DL4_02566 2417681 2418931 + N-acetylglucosamine-6-phosphate deacetylase Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N- acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate%3B Belongs to the NagA family%3B KEGG: bli:BL00084 N-acetylglucosamine-6-phosphate deacetylase gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02566 BL14DL4_02567 BL14DL4_02567 nagB nagB 2418928 2419674 + Glucosamine-6-phosphate deaminase Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bli:BL00085 glucosamine-6-phosphate deaminase gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02567 BL14DL4_02568 BL14DL4_02568 BL14DL4_02568 2419671 2420402 + HTH-type transcriptional repressor YvoA Acts as a weak repressor of yflG expression%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02568 BL14DL4_02569 BL14DL4_02569 murQ murQ 2420399 2421295 + N-acetylmuramic acid 6-phosphate etherase Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: syd:Syncc9605_1393 N-acetylmuramic acid 6-phosphate etherase gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02569 BL14DL4_02570 BL14DL4_02570 nagE nagE 2421298 2422671 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport (By similarity)%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL00088 PTS system%2C N-acetylglucosamine-specific IIB component gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02570 BL14DL4_02571 BL14DL4_02571 BL14DL4_02571 2422929 2422971 + 50S ribosomal protein L9%3B nonfunctional due to frameshift pseudo gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02571 BL14DL4_02572 BL14DL4_02572 BL14DL4_02572 2423153 2425135 - uncharacterized protein Contains 1 GGDEF domain gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02572 BL14DL4_02573 BL14DL4_02573 BL14DL4_02573 2425171 2426064 - uncharacterized protein gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02573 BL14DL4_02574 BL14DL4_02574 BL14DL4_02574 2426614 2427096 + Spore coat protein Belongs to the CotF family gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02574 BL14DL4_02575 BL14DL4_02575 BL14DL4_02575 2427139 2427558 - TRAP-T-associated universal stress protein TeaD ATP-binding protein that negatively regulates activity of the tripartite ATP-independent periplasmic (TRAP) ectoine transport system TeaABC. May regulate uptake according to the ATP status of the cell%3B Belongs to the universal stress protein A family gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02575 BL14DL4_02576 BL14DL4_02576 BL14DL4_02576 2427576 2428847 - Putative sulfate transporter YbaR Belongs to the SLC26A/SulP transporter (TC 2. A. 53) family%3B Contains 1 STAS domain gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02576 BL14DL4_02577 BL14DL4_02577 BL14DL4_02577 2429257 2430558 + putative transporter YybO Belongs to the major facilitator superfamily. Phthalate permease family gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02577 BL14DL4_02578 BL14DL4_02578 BL14DL4_02578 2430636 2430875 - 30S ribosomal protein S18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%2C where it helps stabilize the platform of the 30S subunit%3B Belongs to the ribosomal protein S18P family gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02578 BL14DL4_02579 BL14DL4_02579 BL14DL4_02579 2430927 2431439 - Single-stranded DNA-binding protein Plays an important role in DNA replication%2C recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism%3B Contains 1 SSB domain gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02579 BL14DL4_02580 BL14DL4_02580 BL14DL4_02580 2431486 2431773 - 30S ribosomal protein S6%2C chloroplastic Binds together with S18 to 16S ribosomal RNA%3B Belongs to the ribosomal protein S6P family gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02580 BL14DL4_02581 BL14DL4_02581 BL14DL4_02581 2431887 2432987 - Ribosome-binding ATPase YchF ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner%3B Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily%3B Contains 1 OBG-type G (guanine nucleotide-binding) domain gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02581 BL14DL4_02582 BL14DL4_02582 BL14DL4_02582 2433166 2433375 - uncharacterized protein gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02582 BL14DL4_02583 BL14DL4_02583 BL14DL4_02583 2433460 2434458 - uncharacterized protein gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02583 BL14DL4_02584 BL14DL4_02584 BL14DL4_02584 2434777 2435394 + uncharacterized protein gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02584 BL14DL4_02585 BL14DL4_02585 BL14DL4_02585 2435431 2436279 - Stage 0 sporulation protein J Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division%2C and antagonizes Soj in response to cell cycle events related to chromosome partitioning%3B Belongs to the ParB family gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02585 BL14DL4_02586 BL14DL4_02586 BL14DL4_02586 2436272 2437033 - Putative septum site-determining protein MinD ATPase required for the correct placement of the division site%3B Belongs to the ParA family. MinD subfamily gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02586 BL14DL4_02587 BL14DL4_02587 BL14DL4_02587 2437276 2437719 - uncharacterized protein gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02587 BL14DL4_02588 BL14DL4_02588 BL14DL4_02588 2437786 2438643 - hypothetical protein gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02588 BL14DL4_02589 BL14DL4_02589 BL14DL4_02589 2438699 2439550 - Nucleoid occlusion protein Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid%2C especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid%2C which would cause chromosome breakage%3B Belongs to the ParB family gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02589 BL14DL4_02590 BL14DL4_02590 gidB gidB 2439648 2440400 - 16S rRNA (guanine(527)-N(7))-methyltransferase Specifically methylates the N7 position of guanine in position 535 of 16S rRNA%3B Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family%3B KEGG: bli:BL00108 16S rRNA (guanine527-N7)-methyltransferase gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02590 BL14DL4_02591 BL14DL4_02591 BL14DL4_02591 2440381 2442267 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA-cmnm(5)s(2)U34%3B Belongs to the MnmG family gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02591 BL14DL4_02592 BL14DL4_02592 mnmE mnmE 2442284 2443663 - tRNA modification GTPase MnmE Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs%2C forming tRNA- cmnm(5)s(2)U34%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family%3B Contains 1 TrmE-type G (guanine nucleotide-binding) domain%3B KEGG: bsu:BSU41020 tRNA modification GTPase%3B Acting on acid anhydrides gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02592 BL14DL4_02593 BL14DL4_02593 BL14DL4_02593 2443998 2444621 - Protein jag Contains 1 KH domain%3B Contains 1 R3H domain gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02593 BL14DL4_02594 BL14DL4_02594 BL14DL4_02594 2444618 2445415 - Membrane protein insertase MisCA Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex%2C as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. Essential for sporulation by activating sigma factor SpoIIIG/SigG after engulfment is completed in the prespore%2C maybe by acting on SpoIIIAE. It has an overlapping%2C although partly distinct%2C function compared to YqjG(MisCB)%3B Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02594 BL14DL4_02595 BL14DL4_02595 rnpA rnpA 2445585 2445878 - Ribonuclease P RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4. 5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme%3B Belongs to the RnpA family%3B KEGG: bsu:BSU41050 ribonuclease P protein component gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02595 BL14DL4_02596 BL14DL4_02596 BL14DL4_02596 2446803 2448143 + Chromosomal replication initiator protein DnaA Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replicatio%3B it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids%3B Belongs to the DnaA family gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02596 BL14DL4_02597 BL14DL4_02597 dnaN dnaN 2448320 2449456 + DNA-directed DNA polymerase KEGG: psj:PSJM300_00010 DNA polymerase III subunit beta gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02597 BL14DL4_02598 BL14DL4_02598 BL14DL4_02598 2449624 2449839 + uncharacterized protein Contains 1 S4 RNA-binding domain gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02598 BL14DL4_02599 BL14DL4_02599 BL14DL4_02599 2449856 2450968 + DNA replication and repair protein RecF The RecF protein is involved in DNA metabolis%3B it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded%2C linear DNA. It also seems to bind ATP%3B Belongs to the RecF family gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02599 BL14DL4_02600 BL14DL4_02600 gyrB gyrB 2451282 2453201 + DNA topoisomerase (ATP-hydrolyzing) Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule%3B Belongs to the type II topoisomerase family. ParE type 2 subfamily%3B Contains 1 Toprim domain%3B KEGG: bli:BL00081 DNA gyrase subunit B gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02600 BL14DL4_02601 BL14DL4_02601 gyrA gyrA 2453392 2455860 + DNA topoisomerase (ATP-hydrolyzing) DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings%2C including catenanes and knotted rings%3B Belongs to the topoisomerase GyrA/ParC subunit family%3B KEGG: bli:BL00082 DNA gyrase subunit A gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02601 BL14DL4_02602 BL14DL4_02602 BL14DL4_02602 2456197 2457746 + 16S ribosomal RNA rRNA gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02602 BL14DL4_02603 BL14DL4_02603 BL14DL4_02603 2457849 2457925 + tRNA-Ile tRNA gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02603 BL14DL4_02604 BL14DL4_02604 BL14DL4_02604 2457937 2458012 + tRNA-Ala tRNA gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02604 BL14DL4_02605 BL14DL4_02605 BL14DL4_02605 2458083 2461013 + 23S ribosomal RNA rRNA gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02605 BL14DL4_02606 BL14DL4_02606 BL14DL4_02606 2461145 2461260 + 5S ribosomal RNA rRNA gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02606 BL14DL4_02607 BL14DL4_02607 BL14DL4_02607 2461276 2462253 - uncharacterized protein gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02607 BL14DL4_02608 BL14DL4_02608 BL14DL4_02608 2462375 2463841 + IMP dehydrogenase Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP)%2C the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides%2C and therefore plays an important role in the regulation of cell growth%3B Belongs to the IMPDH/GMPR family%3B Contains 2 CBS domains%3B KEGG: bsu:BSU00090 IMP dehydrogenase gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02608 BL14DL4_02609 BL14DL4_02609 BL14DL4_02609 2463996 2465321 + Serine-type D-Ala-D-Ala carboxypeptidase Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Belongs to the peptidase S11 family%3B KEGG: bss:BSUW23_00055 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02609 BL14DL4_02610 BL14DL4_02610 pdxS pdxS 2465508 2466392 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP)%2C glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates%2C resulting from enzyme-catalyzed isomerization of RBP and G3P%2C respectively%3B Belongs to the PdxS/SNZ family%3B KEGG: bsu:BSU00110 pyridoxal 5'-phosphate synthase pdxS subunit gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02610 BL14DL4_02611 BL14DL4_02611 pdxT pdxT 2466414 2467004 + Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS%3B Belongs to the glutaminase PdxT/SNO family%3B KEGG: bsu:BSU00120 5'-phosphate synthase pdxT subunit gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02611 BL14DL4_02612 BL14DL4_02612 sarS sarS 2467332 2468609 + Serine--tRNA ligase Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine%2C to form the misacylated tRNA L-seryl-tRNA(Sec)%2C which will be further converted into selenocysteinyl-tRNA(Sec)%3B Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily%3B KEGG: dps:DP1764 seryl-tRNA synthetase gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02612 BL14DL4_02613 BL14DL4_02613 glxK glxK 2468639 2469769 - Glycerate 3-kinase Belongs to the glycerate kinase type-1 family%3B KEGG: eco:b0514 glycerate kinase gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02613 BL14DL4_02614 BL14DL4_02614 BL14DL4_02614 2469785 2471053 - putative transporter Belongs to the CitM (TC 2. A. 11) transporter family gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02614 BL14DL4_02615 BL14DL4_02615 BL14DL4_02615 2471110 2472261 - Carbohydrate diacid regulator Seems to regulate the expression of the operons for the enzymes involved in D-galactarate%2C D-glucarate and D-glycerate utilization. Belongs to the CdaR family gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02615 BL14DL4_02616 BL14DL4_02616 BL14DL4_02616 2472291 2472713 - hypothetical protein gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02616 BL14DL4_02617 BL14DL4_02617 BL14DL4_02617 2472843 2472935 + tRNA-Ser tRNA gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02617 BL14DL4_02618 BL14DL4_02618 BL14DL4_02618 2473069 2473710 - Deoxyadenosine kinase Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the nucleoside is less strict. Both 2-deoxyribose%2C ribose%2C and arabinose nucleosides are phosphorylated%2C although the 2-deoxyribonucleosides are preferred. The phosphate donor specificity is dependent on the deoxyribonucleoside substrate%2C but GTP is efficient with both deoxycytidine and deoxyadenosine. Only nucleoside triphosphates can act as phosphate donors%3B Belongs to the DCK/DGK family%3B KEGG: bli:BL02366 deoxyadenosine/deoxycytidine kinase gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02618 BL14DL4_02619 BL14DL4_02619 BL14DL4_02619 2473707 2474330 - Deoxyguanosine kinase Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as phosphate donor than CTP%2C ATP and GTP%3B Belongs to the DCK/DGK family%3B KEGG: bsu:BSU00150 deoxyguanosine kinase gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02619 BL14DL4_02620 BL14DL4_02620 BL14DL4_02620 2474417 2475736 - putative cell wall hydrolase LytN Probably involved in peptidoglycan hydrolysis. Contains 1 LysM repeat%3B Contains 1 peptidase C51 domain gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02620 BL14DL4_02621 BL14DL4_02621 BL14DL4_02621 2475774 2476316 - Isochorismatase Belongs to the isochorismatase family%3B KEGG: cko:CKO_02566 bifunctional isochorismate lyase / aryl carrier protein gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02621 BL14DL4_02622 BL14DL4_02622 tadA tadA 2476405 2476887 + tRNA(adenine(34)) deaminase Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: eca:ECA3260 tRNA(adenine34) deaminase gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02622 BL14DL4_02623 BL14DL4_02623 dnaX dnaX 2477373 2479073 + DNA-directed DNA polymerase DNA polymerase III is a complex%2C multichain enzyme responsible for most of the replicative synthesis in bacteria. Belongs to the DnaX/STICHEL family%3B KEGG: bsu:BSU00190 DNA polymerase III subunit gamma/tau gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02623 BL14DL4_02624 BL14DL4_02624 BL14DL4_02624 2479100 2479423 + Nucleoid-associated protein Binds to DNA and alters its conformation. May be involved in regulation of gene expression%2C nucleoid organization and DNA protection%3B Belongs to the YbaB/EbfC family gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02624 BL14DL4_02625 BL14DL4_02625 BL14DL4_02625 2479437 2480033 + Recombination protein RecR May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO%3B Belongs to the RecR family%3B Contains 1 Toprim domain gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02625 BL14DL4_02626 BL14DL4_02626 BL14DL4_02626 2480054 2480278 + uncharacterized protein gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02626 BL14DL4_02627 BL14DL4_02627 BL14DL4_02627 2480292 2480609 + Sigma-K factor-processing regulatory protein BofA Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB-processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site%2C preventing access of a water molecule and the sequence of pro- sigma K%2C which are necessary for peptide bond hydrolysis to produce sigma-K gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02627 BL14DL4_02628 BL14DL4_02628 BL14DL4_02628 2480894 2482443 + 16S ribosomal RNA rRNA gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02628 BL14DL4_02629 BL14DL4_02629 BL14DL4_02629 2482546 2482622 + tRNA-Ile tRNA gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02629 BL14DL4_02630 BL14DL4_02630 BL14DL4_02630 2482634 2482709 + tRNA-Ala tRNA gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02630 BL14DL4_02631 BL14DL4_02631 BL14DL4_02631 2482780 2485709 + 23S ribosomal RNA rRNA gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02631 BL14DL4_02632 BL14DL4_02632 BL14DL4_02632 2485842 2485957 + 5S ribosomal RNA rRNA gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02632 BL14DL4_02633 BL14DL4_02633 BL14DL4_02633 2486126 2486317 + Protein CsfB gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02633 BL14DL4_02634 BL14DL4_02634 BL14DL4_02634 2486510 2487127 + Protein XpaC gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02634 BL14DL4_02635 BL14DL4_02635 BL14DL4_02635 2487143 2488336 + uncharacterized protein Belongs to the TelA family gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02635 BL14DL4_02636 BL14DL4_02636 ldcC ldcC 2488477 2489919 + Lysine decarboxylase Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bca:BCE_0027 lysine decarboxylase gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02636 BL14DL4_02637 BL14DL4_02637 BL14DL4_02637 2489916 2490554 + dTMP kinase Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis%3B Belongs to the thymidylate kinase family%3B KEGG: pol:Bpro_2519 dTMP kinase gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02637 BL14DL4_02638 BL14DL4_02638 BL14DL4_02638 2490630 2490959 + uncharacterized protein gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02638 BL14DL4_02639 BL14DL4_02639 BL14DL4_02639 2490971 2491411 + uncharacterized protein gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02639 BL14DL4_02640 BL14DL4_02640 holB holB 2491423 2492412 + DNA-directed DNA polymerase KEGG: bli:BL00541 DNA polymerase III subunit delta' gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02640 BL14DL4_02641 BL14DL4_02641 BL14DL4_02641 2492415 2493242 + Stage 0 sporulation protein YaaT Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation%3B Contains 1 PSP1 C-terminal domain gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02641 BL14DL4_02642 BL14DL4_02642 BL14DL4_02642 2493257 2493619 + Initiation-control protein YabA Involved in initiation control of chromosome replication%3B Belongs to the YabA family gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02642 BL14DL4_02643 BL14DL4_02643 BL14DL4_02643 2493684 2494427 + uncharacterized protein gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02643 BL14DL4_02644 BL14DL4_02644 BL14DL4_02644 2494414 2494707 + UPF0213 protein Belongs to the UPF0213 family%3B Contains 1 GIY-YIG domain gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02644 BL14DL4_02645 BL14DL4_02645 rsmI rsmI 2494679 2495614 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmI family%3B KEGG: bli:BL00535 16S rRNA (cytidine1402-2'-O)-methyltransferase gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02645 BL14DL4_02646 BL14DL4_02646 BL14DL4_02646 2495605 2495889 - Transition state regulatory protein AbrB Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites%2C it may be the sole repressor of tycA transcription%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis Abh and SpoVT gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02646 BL14DL4_02647 BL14DL4_02647 marS marS 2496403 2498391 + Methionine--tRNA ligase Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation%3B Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily%3B Contains 1 tRNA-binding domain%3B KEGG: bli:BL00533 methionyl-tRNA synthetase gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02647 BL14DL4_02648 BL14DL4_02648 tatD tatD 2498476 2499243 + putative metal-dependent hydrolase YabD Belongs to the TatD-type hydrolase family%3B KEGG: bsu:BSU00390 TatD DNase family protein%3B Endodeoxyribonucleases producing 5'-phosphomonoesters gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02648 BL14DL4_02649 BL14DL4_02649 BL14DL4_02649 2499273 2500685 + uncharacterized protein Contains 1 G5 domain gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02649 BL14DL4_02650 BL14DL4_02650 rnmV rnmV 2500853 2501413 + Ribonuclease M5 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step%3B Belongs to the ribonuclease M5 family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU00410 ribonuclease M5 gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02650 BL14DL4_02651 BL14DL4_02651 ksgA ksgA 2501406 2502284 + 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits%3B Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily%3B KEGG: bsu:BSU00420 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02651 BL14DL4_02652 BL14DL4_02652 BL14DL4_02652 2502444 2503325 + Sporulation-specific protease YabG Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross- linking of coat proteins like GerQ%3B Belongs to the peptidase U57 family gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02652 BL14DL4_02653 BL14DL4_02653 BL14DL4_02653 2503550 2503810 + Protein Veg Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity%2C independently of the SinI%2C SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02653 BL14DL4_02654 BL14DL4_02654 BL14DL4_02654 2503967 2504152 + Protein SspF May play some important role in either sporulation or the dormant spore. Belongs to the alpha/beta-type SASP family gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02654 BL14DL4_02655 BL14DL4_02655 BL14DL4_02655 2504207 2504377 - hypothetical protein gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02655 BL14DL4_02656 BL14DL4_02656 ispE ispE 2504450 2505319 + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol%3B Belongs to the GHMP kinase family. IspE subfamily%3B KEGG: rhl:LPU83_0984 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02656 BL14DL4_02657 BL14DL4_02657 BL14DL4_02657 2505376 2506209 + Pur operon repressor Controls the transcription of the pur operon for purine biosynthetic genes%2C binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate. Belongs to the purine/pyrimidine phosphoribosyltransferase family gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02657 BL14DL4_02658 BL14DL4_02658 ridA ridA 2506227 2506604 + 2-iminobutanoate/2-iminopropanoate deaminase Belongs to the RutC family%3B KEGG: bcib:IM45_599 2-iminobutanoate/2-iminopropanoate deaminase gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02658 BL14DL4_02659 BL14DL4_02659 BL14DL4_02659 2506784 2507077 + Putative septation protein SpoVG Could be involved in septation%3B Belongs to the SpoVG family gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02659 BL14DL4_02660 BL14DL4_02660 glmU glmU 2507382 2508752 + UDP-N-acetylglucosamine diphosphorylase Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P)%2C which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate)%2C a reaction catalyzed by the N-terminal domain%3B In the N-terminal sectio%3B belongs to the N- acetylglucosamine-1-phosphate uridyltransferase family%3B In the C-terminal sectio%3B belongs to the transferase hexapeptide repeat family%3B KEGG: bsu:BSU00500 bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02660 BL14DL4_02661 BL14DL4_02661 prpS prpS 2508773 2509723 + Ribose-phosphate diphosphokinase Involved in the biosynthesis of ribose 1%2C5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP%3B Belongs to the ribose-phosphate pyrophosphokinase family%3B KEGG: bli:BL00519 ribose-phosphate pyrophosphokinase gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02661 BL14DL4_02662 BL14DL4_02662 BL14DL4_02662 2509804 2510430 + 50S ribosomal protein L25 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance%3B Belongs to the ribosomal protein L25P family. CTC subfamily gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02662 BL14DL4_02663 BL14DL4_02663 pth1 pth1 2510547 2511113 + Aminoacyl-tRNA hydrolase The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis%3B Belongs to the PTH family%3B KEGG: mlo:mlr2694 peptidyl-tRNA hydrolase%2C PTH1 family gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02663 BL14DL4_02664 BL14DL4_02664 BL14DL4_02664 2511170 2511400 + uncharacterized protein gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02664 BL14DL4_02665 BL14DL4_02665 BL14DL4_02665 2511465 2514998 + Transcription-repair-coupling factor Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA%2C and recruitment of nucleotide excision repair machinery to the damaged site%3B In the N-terminal sectio%3B belongs to the UvrB family%3B In the C-terminal sectio%3B belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU00550 transcription-repair coupling factor (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02665 BL14DL4_02666 BL14DL4_02666 BL14DL4_02666 2515136 2515672 + Stage V sporulation protein Positive and negative transcriptional regulator of sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development%3B Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and Abh gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02666 BL14DL4_02667 BL14DL4_02667 BL14DL4_02667 2515886 2517478 + putative membrane protein YabM Belongs to the polysaccharide synthase family gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02667 BL14DL4_02668 BL14DL4_02668 BL14DL4_02668 2517468 2518937 + uncharacterized protein gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02668 BL14DL4_02669 BL14DL4_02669 BL14DL4_02669 2518944 2519207 + uncharacterized protein Contains 1 S4 RNA-binding domain gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02669 BL14DL4_02670 BL14DL4_02670 BL14DL4_02670 2519284 2519592 + Spore protein YabP Required for sporulation gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02670 BL14DL4_02671 BL14DL4_02671 BL14DL4_02671 2519589 2520215 + Spore protein YabQ Required for sporulation. Plays an important role in cortex and coat formation gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02671 BL14DL4_02672 BL14DL4_02672 BL14DL4_02672 2520232 2520609 + Cell division protein DivIC gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02672 BL14DL4_02673 BL14DL4_02673 BL14DL4_02673 2520689 2521087 + uncharacterized protein Belongs to the peptidase U57 family%3B Contains 1 S1 motif domain gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02673 BL14DL4_02674 BL14DL4_02674 BL14DL4_02674 2521238 2521311 + tRNA-Met tRNA gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02674 BL14DL4_02675 BL14DL4_02675 BL14DL4_02675 2521322 2521393 + tRNA-Glu tRNA gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02675 BL14DL4_02676 BL14DL4_02676 BL14DL4_02676 2521603 2524092 + Protein-serine/threonine phosphatase Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation. Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU00640 stage II sporulation protein E gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02676 BL14DL4_02677 BL14DL4_02677 BL14DL4_02677 2524169 2524906 + uncharacterized protein gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02677 BL14DL4_02678 BL14DL4_02678 BL14DL4_02678 2524875 2525909 + Non-specific serine/threonine protein kinase Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bli:BL00504 serine/threonine protein kinase%2C bacterial gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02678 BL14DL4_02679 BL14DL4_02679 tilS tilS 2526012 2527442 + tRNA(Ile)-lysidine synthetase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%2C in an ATP-dependent manner. Cytidine is converted to lysidine%2C thus changing the amino acid specificity of the tRNA from methionine to isoleucine%3B Belongs to the tRNA(Ile)-lysidine synthase family%3B KEGG: bli:BL00503 tRNA(Ile)-lysidine synthase gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02679 BL14DL4_02680 BL14DL4_02680 hprT hprT 2527426 2527965 + Hypoxanthine phosphoribosyltransferase Belongs to the purine/pyrimidine phosphoribosyltransferase family%3B KEGG: bli:BL05003 hypoxanthine phosphoribosyltransferase gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02680 BL14DL4_02681 BL14DL4_02681 ftsH ftsH 2528062 2529981 + ATP-dependent zinc metalloprotease FtsH Acts as a processive%2C ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins%3B In the central sectio%3B belongs to the AAA ATPase family%3B In the C-terminal sectio%3B belongs to the peptidase M41 family%3B KEGG: bsu:BSU00690 cell division protease FtsH%3B Metalloendopeptidases gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02681 BL14DL4_02682 BL14DL4_02682 coaX coaX 2530184 2530960 + Pantothenate kinase Catalyzes the phosphorylation of pantothenate (Pan)%2C the first step in CoA biosynthesis%3B Belongs to the type III pantothenate kinase family%3B KEGG: gsu:GSU1934 type III pantothenate kinase gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02682 BL14DL4_02683 BL14DL4_02683 BL14DL4_02683 2530972 2531841 + 33 kDa chaperonin Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress%3B Belongs to the HSP33 family gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02683 BL14DL4_02684 BL14DL4_02684 prsA prsA 2531894 2532784 + Peptidylprolyl isomerase Contains 1 PpiC domain%3B KEGG: baci:B1NLA3E_00340 foldase protein PrsA gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02684 BL14DL4_02685 BL14DL4_02685 BL14DL4_02685 2532860 2533783 + Cysteine synthase Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cysteine is present%2C the pool of O-acetylserine (OAS) is low%2C which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine%2C the OAS pool is high and the CymR-CysK complex is mostly dissociated%2C leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression%3B Belongs to the cysteine synthase/cystathionine beta- synthase family%3B KEGG: bsu:BSU00730 cysteine synthase A gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02685 BL14DL4_02686 BL14DL4_02686 pabB pabB 2533980 2535413 + Aminodeoxychorismate synthase Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC%3B Belongs to the anthranilate synthase component I family%3B KEGG: bld:BLi00090 para-aminobenzoate synthetase component I gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02686 BL14DL4_02687 BL14DL4_02687 pabA pabA 2535410 2535994 + Aminodeoxychorismate synthase Part of a heterodimeric complex that catalyzes the two- step biosynthesis of 4-amino-4-deoxychorismate (ADC)%2C a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step%2C a glutamine amidotransferase (PabA) generates ammonia as a substrate that%2C along with chorismate%2C is used in the second step%2C catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. Also involved in the biosynthesis of anthranilate%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: eco:b3360 para-aminobenzoate synthetase component II gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02687 BL14DL4_02688 BL14DL4_02688 BL14DL4_02688 2535991 2536851 + Branched-chain-amino-acid transaminase Acts on leucine%2C isoleucine and valine%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: eca:ECA2971 branched-chain amino acid aminotransferase gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02688 BL14DL4_02689 BL14DL4_02689 folP folP 2536864 2537721 + Dihydropteroate synthase Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7%2C8-dihydropterin diphosphate (DHPt-PP) to form 7%2C8-dihydropteroate (H2Pte)%2C the immediate precursor of folate derivatives%3B Belongs to the DHPS family%3B Contains 1 pterin-binding domain%3B KEGG: bli:BL00861 dihydropteroate synthase gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02689 BL14DL4_02690 BL14DL4_02690 folB folB 2537693 2538076 + Dihydroneopterin aldolase Catalyzes the conversion of 7%2C8-dihydroneopterin to 6- hydroxymethyl-7%2C8-dihydropterin%3B Belongs to the DHNA family%3B KEGG: bli:BL00862 dihydroneopterin aldolase gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02690 BL14DL4_02691 BL14DL4_02691 folK folK 2538073 2538573 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase Belongs to the HPPK family%3B KEGG: bli:BL05004 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02691 BL14DL4_02692 BL14DL4_02692 BL14DL4_02692 2538525 2538734 + putative HTH-type transcriptional regulator YazB Contains 1 HTH cro/C1-type DNA-binding domain gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02692 BL14DL4_02693 BL14DL4_02693 dusB dusB 2538751 2539752 + putative tRNA-dihydrouridine synthase Catalyzes the synthesis of 5%2C6-dihydrouridine (D)%2C a modified base found in the D-loop of most tRNAs%2C via the reduction of the C5-C6 double bond in target uridines%3B Belongs to the Dus family%3B KEGG: rpo:MA1_00045 tRNA-dihydrouridine synthase B%3B Oxidoreductases gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02693 BL14DL4_02694 BL14DL4_02694 karS karS 2539834 2541336 + Lysine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: blh:BaLi_c00980 lysyl-tRNA synthetase%2C class II gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02694 BL14DL4_02695 BL14DL4_02695 BL14DL4_02695 2541634 2543183 + 16S ribosomal RNA rRNA gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02695 BL14DL4_02696 BL14DL4_02696 BL14DL4_02696 2543358 2546288 + 23S ribosomal RNA rRNA gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02696 BL14DL4_02697 BL14DL4_02697 BL14DL4_02697 2546420 2546535 + 5S ribosomal RNA rRNA gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02697 BL14DL4_02698 BL14DL4_02698 BL14DL4_02698 2546556 2546631 + tRNA-Val tRNA gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02698 BL14DL4_02699 BL14DL4_02699 BL14DL4_02699 2546653 2546728 + tRNA-Thr tRNA gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02699 BL14DL4_02700 BL14DL4_02700 BL14DL4_02700 2546764 2546839 + tRNA-Lys tRNA gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02700 BL14DL4_02701 BL14DL4_02701 BL14DL4_02701 2546846 2546928 + tRNA-Leu tRNA gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02701 BL14DL4_02702 BL14DL4_02702 BL14DL4_02702 2546945 2547019 + tRNA-Gly tRNA gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02702 BL14DL4_02703 BL14DL4_02703 BL14DL4_02703 2547029 2547114 + tRNA-Leu tRNA gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02703 BL14DL4_02704 BL14DL4_02704 BL14DL4_02704 2547124 2547200 + tRNA-Arg tRNA gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02704 BL14DL4_02705 BL14DL4_02705 BL14DL4_02705 2547211 2547287 + tRNA-Pro tRNA gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02705 BL14DL4_02706 BL14DL4_02706 BL14DL4_02706 2547294 2547369 + tRNA-Ala tRNA gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02706 BL14DL4_02707 BL14DL4_02707 BL14DL4_02707 2547525 2549074 + 16S ribosomal RNA rRNA gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02707 BL14DL4_02708 BL14DL4_02708 BL14DL4_02708 2549249 2552179 + 23S ribosomal RNA rRNA gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02708 BL14DL4_02709 BL14DL4_02709 BL14DL4_02709 2552311 2552426 + 5S ribosomal RNA rRNA gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02709 BL14DL4_02710 BL14DL4_02710 BL14DL4_02710 2552603 2553067 + Transcriptional regulator CtsR Controls the expression of the cellular protein quality control genes clpC%2C clpE and clpP%2C as well as mcsA and mcsB. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock%2C CtsR is degraded by the ClpCP and ClpEP proteolytic systems%2C ensuring the derepression of clpE%2C clpP and the clpC operon. CtsR negatively autoregulates its own synthesis%3B Belongs to the CtsR family gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02710 BL14DL4_02711 BL14DL4_02711 BL14DL4_02711 2553205 2553636 + Protein-arginine kinase activator protein Activates the phosphorylation activity of the protein- arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles%3B Contains 1 UVR domain gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02711 BL14DL4_02712 BL14DL4_02712 mcsB mcsB 2553636 2554727 + Protein arginine kinase Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes%2C such as protein homeostasis%2C motility%2C competence%2C and stringent and stress responses%2C by regulating gene expression and protein activity%3B Belongs to the ATP:guanido phosphotransferase family%3B Contains 1 phosphagen kinase C-terminal domain%3B KEGG: bli:BL03260 protein arginine kinase gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02712 BL14DL4_02713 BL14DL4_02713 BL14DL4_02713 2554724 2557156 + Chaperone protein ClpB Part of a stress-induced multi-chaperone system%2C it is involved in the recovery of the cell from heat-induced damage%2C in cooperation with DnaK%2C DnaJ and GrpE. Acts before DnaK%2C in the processing of protein aggregates. Protein binding stimulates the ATPase activit%3B ATP hydrolysis unfolds the denatured protein aggregates%2C which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates%2C contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)%3B Belongs to the ClpA/ClpB family%3B Contains 1 UVR domain gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02713 BL14DL4_02714 BL14DL4_02714 BL14DL4_02714 2557332 2558615 + DNA repair protein RadA like protein May play a role in the repair of endogenous alkylation damage%3B Belongs to the RecA family. RadA subfamily gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02714 BL14DL4_02715 BL14DL4_02715 disA disA 2558619 2559695 + Diadenylate cyclase Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation%2C searching for lesions. When a lesion is present%2C DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation%3B Has also diadenylate cyclase activity%2C catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome%2C operates as a positive signal that advances sporulatio%3B upon encountering a lesion%2C the DisA focus arrests at the damaged site and halts c-di- AMP synthesis%3B Belongs to the DisA family%3B KEGG: bli:BL03263 diadenylate cyclase gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02715 BL14DL4_02716 BL14DL4_02716 BL14DL4_02716 2559827 2560915 + putative PIN and TRAM-domain containing protein YacL An RNase%3B Belongs to the ycf81 family%3B In the central sectio%3B belongs to the PINc/VapC protein family%3B Contains 1 PINc domain%3B Contains 1 TRAM domain gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02716 BL14DL4_02717 BL14DL4_02717 ispD ispD 2560932 2561627 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)%3B Belongs to the IspD family%3B KEGG: bsu:BSU00900 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02717 BL14DL4_02718 BL14DL4_02718 ispF ispF 2561620 2562096 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD)%2C and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2%2C4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)%3B In the N-terminal sectio%3B belongs to the IspD family%3B In the C-terminal sectio%3B belongs to the IspF family%3B KEGG: ctu:CTU_33200 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02718 BL14DL4_02719 BL14DL4_02719 gltX gltX 2562178 2563635 + Glutamate--tRNA(Gln) ligase Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)%3B Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bsu:BSU00920 nondiscriminating glutamyl-tRNA synthetase gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02719 BL14DL4_02720 BL14DL4_02720 BL14DL4_02720 2563937 2564587 + Serine O-acetyltransferase Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS)%3B Belongs to the transferase hexapeptide repeat family%3B KEGG: cha:CHAB381_0927 serine O-acetyltransferase gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02720 BL14DL4_02721 BL14DL4_02721 carS carS 2564584 2565987 + Cysteine--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: fau:Fraau_2118 cysteinyl-tRNA synthetase gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02721 BL14DL4_02722 BL14DL4_02722 BL14DL4_02722 2565990 2566406 + Mini-ribonuclease Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc%3B Rnc processes 30S rRNA into smaller rRNA precursors. Cleaves more efficiently on assembled 50S ribosomal subunits. Cleavage is strongly stimulated by ribosomal protein L3 (RplC%3B 20-30%25 DMSO can replace RplC%2C suggesting RplC may alter rRNA conformation%3B Belongs to the MrnC RNase family%3B KEGG: bli:BL03270 ribonuclease III family protein%3B Endoribonucleases producing 5'-phosphomonoesters gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02722 BL14DL4_02723 BL14DL4_02723 rlmB rlmB 2566403 2567152 + 23S rRNA (guanosine(2251)-2'-O)-methyltransferase Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family%3B KEGG: bsu:BSU00960 23S rRNA (guanosine2251-2'-O)-methyltransferase gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02723 BL14DL4_02724 BL14DL4_02724 BL14DL4_02724 2567158 2567670 + uncharacterized protein gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02724 BL14DL4_02725 BL14DL4_02725 BL14DL4_02725 2567734 2568405 + RNA polymerase sigma-H factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation. Belongs to the sigma-70 factor family gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02725 BL14DL4_02726 BL14DL4_02726 BL14DL4_02726 2568673 2568852 + Protein translocase subunit SecE Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation%3B Belongs to the SecE/SEC61-gamma family gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02726 BL14DL4_02727 BL14DL4_02727 BL14DL4_02727 2569024 2569563 + Transcription termination/antitermination protein NusG Participates in transcription elongation%2C termination and antitermination. In the absence of Rho%2C increases the rate of transcription elongation by the RNA polymerase (RNAP)%2C probably by partially suppressing pausing. In the presence of Rho%2C modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination%3B Belongs to the NusG family%3B Contains 1 KOW domain gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02727 BL14DL4_02728 BL14DL4_02728 BL14DL4_02728 2569733 2570158 + 50S ribosomal protein L11-1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors%3B Belongs to the ribosomal protein L11P family gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02728 BL14DL4_02729 BL14DL4_02729 BL14DL4_02729 2570260 2570958 + 50S ribosomal protein L1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome%2C and is involved in E site tRNA release%3B Protein L1 is also a translational repressor protein%2C it controls the translation of the L11 operon by binding to its mRNA%3B Belongs to the ribosomal protein L1P family gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02729 BL14DL4_02730 BL14DL4_02730 BL14DL4_02730 2571220 2571720 + 50S ribosomal protein L10 Forms part of the ribosomal stalk%2C playing a central role in the interaction of the ribosome with GTP-bound translation factors%3B Belongs to the ribosomal protein L10P family gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02730 BL14DL4_02731 BL14DL4_02731 BL14DL4_02731 2571765 2572136 + 50S ribosomal protein L7/L12 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation%3B Belongs to the ribosomal protein L7/L12P family gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02731 BL14DL4_02732 BL14DL4_02732 rsmC rsmC 2572276 2572881 + 16S rRNA (guanine(1207)-N(2))-methyltransferase Belongs to the methyltransferase superfamily%3B KEGG: bsu:BSU01060 16S rRNA (guanine1207-N2)-methyltransferase gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02732 BL14DL4_02733 BL14DL4_02733 rpoB rpoB 2573132 2576713 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta chain family%3B KEGG: bsu:BSU01070 DNA-directed RNA polymerase subunit beta gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02733 BL14DL4_02734 BL14DL4_02734 rpoC rpoC 2576773 2580372 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase beta' chain family%3B KEGG: ssdc:SSDC_00130 DNA-directed RNA polymerase subunit beta' gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02734 BL14DL4_02735 BL14DL4_02735 BL14DL4_02735 2580492 2580740 + Putative ribosomal protein L7Ae-like Belongs to the ribosomal protein L7Ae family gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02735 BL14DL4_02736 BL14DL4_02736 BL14DL4_02736 2580845 2581261 + 30S ribosomal protein S12 With S4 and S5 plays an important role in translational accuracy%3B Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits%2C it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8%2C S12 and S17 appears to hold together the shoulder and platform of the 30S subunit%3B Belongs to the ribosomal protein S12P family gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02736 BL14DL4_02737 BL14DL4_02737 BL14DL4_02737 2581427 2581897 + 30S ribosomal protein S7 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center%2C probably blocks exit of the E-site tRNA%3B Belongs to the ribosomal protein S7P family gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02737 BL14DL4_02738 BL14DL4_02738 BL14DL4_02738 2581947 2584025 + Elongation factor G Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step%2C the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites%2C respectively. Catalyzes the coordinated movement of the two tRNA molecules%2C the mRNA and conformational changes in the ribosome%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02738 BL14DL4_02739 BL14DL4_02739 BL14DL4_02739 2584145 2585335 + Elongation factor Tu-A This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02739 BL14DL4_02740 BL14DL4_02740 BL14DL4_02740 2585657 2585965 + 30S ribosomal protein S10%2C chloroplastic Involved in the binding of tRNA to the ribosomes%3B Belongs to the ribosomal protein S10P family gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02740 BL14DL4_02741 BL14DL4_02741 BL14DL4_02741 2586004 2586633 + 50S ribosomal protein L3 One of the primary rRNA binding proteins%2C it binds directly near the 3'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B Belongs to the ribosomal protein L3P family gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02741 BL14DL4_02742 BL14DL4_02742 BL14DL4_02742 2586661 2587284 + 50S ribosomal protein L4 One of the primary rRNA binding proteins%2C this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B Forms part of the polypeptide exit tunnel%3B Belongs to the ribosomal protein L4P family gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02742 BL14DL4_02743 BL14DL4_02743 BL14DL4_02743 2587284 2587571 + 50S ribosomal protein L23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome%3B Belongs to the ribosomal protein L23P family gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02743 BL14DL4_02744 BL14DL4_02744 BL14DL4_02744 2587603 2588436 + 50S ribosomal protein L2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activit%3B this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome%3B Belongs to the ribosomal protein L2P family gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02744 BL14DL4_02745 BL14DL4_02745 BL14DL4_02745 2588494 2588772 + 30S ribosomal protein S19%2C chloroplastic Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA%3B Belongs to the ribosomal protein S19P family gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02745 BL14DL4_02746 BL14DL4_02746 BL14DL4_02746 2588790 2589134 + 50S ribosomal protein L22 This protein binds specifically to 23S rRN%3B its binding is stimulated by other ribosomal proteins%2C e. g. L4%2C L17%2C and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)%3B The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit%2C while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome%3B Belongs to the ribosomal protein L22P family gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02746 BL14DL4_02747 BL14DL4_02747 BL14DL4_02747 2589138 2589794 + 30S ribosomal protein S3%2C chloroplastic Belongs to the ribosomal protein S3P family%3B Contains 1 KH type-2 domain gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02747 BL14DL4_02748 BL14DL4_02748 BL14DL4_02748 2589796 2590230 + 50S ribosomal protein L16%2C plastid Belongs to the ribosomal protein L16P family gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02748 BL14DL4_02749 BL14DL4_02749 BL14DL4_02749 2590220 2590420 + 50S ribosomal protein L29 Belongs to the ribosomal protein L29P family gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02749 BL14DL4_02750 BL14DL4_02750 BL14DL4_02750 2590445 2590708 + 30S ribosomal protein S17 One of the primary rRNA binding proteins%2C it binds specifically to the 5'-end of 16S ribosomal RNA%3B Belongs to the ribosomal protein S17P family gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02750 BL14DL4_02751 BL14DL4_02751 BL14DL4_02751 2590749 2591117 + 50S ribosomal protein L14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome%3B Belongs to the ribosomal protein L14P family gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02751 BL14DL4_02752 BL14DL4_02752 BL14DL4_02752 2591153 2591464 + 50S ribosomal protein L24 One of two assembly initiator proteins%2C it binds directly to the 5'-end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit%3B Belongs to the ribosomal protein L24P family gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02752 BL14DL4_02753 BL14DL4_02753 BL14DL4_02753 2591490 2592029 + 50S ribosomal protein L5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b)%2C connecting the 2 subunit%3B this bridge is implicated in subunit movement. Contacts the P site tRN%3B the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs%3B Belongs to the ribosomal protein L5P family gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02753 BL14DL4_02754 BL14DL4_02754 BL14DL4_02754 2592052 2592237 + 30S ribosomal protein S14 type Z Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family. Zinc- binding S14P subfamily gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02754 BL14DL4_02755 BL14DL4_02755 BL14DL4_02755 2592269 2592667 + 30S ribosomal protein S8 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit%3B Belongs to the ribosomal protein S8P family gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02755 BL14DL4_02756 BL14DL4_02756 BL14DL4_02756 2592697 2593233 + 50S ribosomal protein L6%2C cyanelle Binds 23S rRNA%3B Belongs to the ribosomal protein L6P family gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02756 BL14DL4_02757 BL14DL4_02757 BL14DL4_02757 2593265 2593627 + 50S ribosomal protein L18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit%2C where it forms part of the central protuberance%3B Belongs to the ribosomal protein L18P family gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02757 BL14DL4_02758 BL14DL4_02758 BL14DL4_02758 2593646 2594152 + 30S ribosomal protein With S4 and S12 plays an important role in translational accuracy%3B Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B Belongs to the ribosomal protein S5P family%3B Contains 1 S5 DRBM domain gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02758 BL14DL4_02759 BL14DL4_02759 BL14DL4_02759 2594166 2594345 + 50S ribosomal protein L30 Belongs to the ribosomal protein L30P family gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02759 BL14DL4_02760 BL14DL4_02760 BL14DL4_02760 2594376 2594816 + 50S ribosomal protein L15 Binds to the 23S rRNA%3B Belongs to the ribosomal protein L15P family gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02760 BL14DL4_02761 BL14DL4_02761 BL14DL4_02761 2594818 2596113 + Protein translocase subunit SecY The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7%2C and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently%3B Belongs to the SecY/SEC61-alpha family gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02761 BL14DL4_02762 BL14DL4_02762 BL14DL4_02762 2596167 2596820 + Adenylate kinase Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism%3B Belongs to the adenylate kinase family%3B KEGG: cbu:CBU_0454 adenylate kinase gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02762 BL14DL4_02763 BL14DL4_02763 BL14DL4_02763 2596817 2597563 + Methionyl aminopeptidase Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: bsu:BSU01380 methionyl aminopeptidase gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02763 BL14DL4_02764 BL14DL4_02764 BL14DL4_02764 2597574 2597903 + Putative ribosome-binding protein YbzG gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02764 BL14DL4_02765 BL14DL4_02765 BL14DL4_02765 2597881 2598099 + Translation initiation factor IF-1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection%2C yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1%2C IF-2 and IF-3 are released leaving the mature 70S translation initation complex%3B Belongs to the IF-1 family%3B Contains 1 S1-like domain gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02765 BL14DL4_02766 BL14DL4_02766 BL14DL4_02766 2598133 2598246 + 50S ribosomal protein L36%2C chloroplastic Belongs to the ribosomal protein L36P family gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02766 BL14DL4_02767 BL14DL4_02767 BL14DL4_02767 2598269 2598634 + Cyanelle 30S ribosomal protein S13 Located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B Belongs to the ribosomal protein S13P family gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02767 BL14DL4_02768 BL14DL4_02768 BL14DL4_02768 2598655 2599050 + 30S ribosomal protein S11 Located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B Belongs to the ribosomal protein S11P family gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02768 BL14DL4_02769 BL14DL4_02769 rpoA rpoA 2599225 2600169 + DNA-directed RNA polymerase DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B Belongs to the RNA polymerase alpha chain family%3B KEGG: bsu:BSU01430 DNA-directed RNA polymerase subunit alpha gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02769 BL14DL4_02770 BL14DL4_02770 BL14DL4_02770 2600247 2600609 + 50S ribosomal protein L17 Belongs to the ribosomal protein L17P family gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02770 BL14DL4_02771 BL14DL4_02771 BL14DL4_02771 2600751 2601596 + Energy-coupling factor transporter ATP-binding protein EcfA1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL01023 energy-coupling factor transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02771 BL14DL4_02772 BL14DL4_02772 BL14DL4_02772 2601572 2602441 + Energy-coupling factor transporter ATP-binding protein EcfA2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the ABC transporter superfamily. Energy- coupling factor EcfA family%3B Contains 1 ABC transporter domain gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02772 BL14DL4_02773 BL14DL4_02773 BL14DL4_02773 2602438 2603235 + Energy-coupling factor transporter transmembrane protein EcfT Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates%3B Belongs to the energy-coupling factor EcfT family gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02773 BL14DL4_02774 BL14DL4_02774 truA truA 2603246 2603989 + tRNA pseudouridine(38-40) synthase Formation of pseudouridine at positions 38%2C 39 and 40 in the anticodon stem and loop of transfer RNAs%3B Belongs to the tRNA pseudouridine synthase TruA family%3B KEGG: bsu:BSU01480 tRNA pseudouridine38-40 synthase gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02774 BL14DL4_02775 BL14DL4_02775 BL14DL4_02775 2604150 2604587 + 50S ribosomal protein L13 This protein is one of the early assembly proteins of the 50S ribosomal subunit%2C although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly%3B Belongs to the ribosomal protein L13P family gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02775 BL14DL4_02776 BL14DL4_02776 BL14DL4_02776 2604608 2605000 + 30S ribosomal protein S9 Belongs to the ribosomal protein S9P family gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02776 BL14DL4_02777 BL14DL4_02777 BL14DL4_02777 2605051 2605509 - uncharacterized protein Belongs to the DinB family gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02777 BL14DL4_02778 BL14DL4_02778 BL14DL4_02778 2605621 2606064 + uncharacterized protein gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02778 BL14DL4_02779 BL14DL4_02779 BL14DL4_02779 2606157 2606870 + N-acetylmuramoyl-L-alanine amidase Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan. This is a step in the formation of muramic delta-lactam residues in spore cortex%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B KEGG: bsu:BSU01530 N-acetylmuramoyl-L-alanine amidase gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02779 BL14DL4_02780 BL14DL4_02780 BL14DL4_02780 2606911 2608017 + Iron-sulfur cluster carrier protein Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP%3B Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect%3B Belongs to the Mrp/NBP35 ATP-binding proteins family gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02780 BL14DL4_02781 BL14DL4_02781 BL14DL4_02781 2608071 2608652 - Spore germination protein GerD gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02781 BL14DL4_02782 BL14DL4_02782 BL14DL4_02782 2608767 2609366 + KinB-signaling pathway activation protein Involved in the activation of the KinB signaling pathway of sporulation gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02782 BL14DL4_02783 BL14DL4_02783 BL14DL4_02783 2609375 2610139 - putative polysaccharide deacetylase PdaB Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation%3B Belongs to the polysaccharide deacetylase family%3B KEGG: css:Cst_c05460 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02783 BL14DL4_02784 BL14DL4_02784 BL14DL4_02784 2610479 2612028 + 16S ribosomal RNA rRNA gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02784 BL14DL4_02785 BL14DL4_02785 BL14DL4_02785 2612203 2615133 + 23S ribosomal RNA rRNA gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02785 BL14DL4_02786 BL14DL4_02786 BL14DL4_02786 2615266 2615381 + 5S ribosomal RNA rRNA gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02786 BL14DL4_02787 BL14DL4_02787 BL14DL4_02787 2615424 2615498 + tRNA-Asn tRNA gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02787 BL14DL4_02788 BL14DL4_02788 BL14DL4_02788 2615501 2615573 + tRNA-Thr tRNA gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02788 BL14DL4_02789 BL14DL4_02789 BL14DL4_02789 2615697 2615864 - hypothetical protein gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02789 BL14DL4_02790 BL14DL4_02790 BL14DL4_02790 2615958 2617127 - Putative penicillin-binding protein PbpX Belongs to the beta-lactamase family gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02790 BL14DL4_02791 BL14DL4_02791 BL14DL4_02791 2617302 2617523 + hypothetical protein gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02791 BL14DL4_02792 BL14DL4_02792 BL14DL4_02792 2617635 2618612 + Tagaturonate reductase KEGG: sbu:SpiBuddy_3010 tagaturonate reductase gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02792 BL14DL4_02793 BL14DL4_02793 BL14DL4_02793 2618647 2619060 + uncharacterized protein gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02793 BL14DL4_02794 BL14DL4_02794 phzF phzF 2619207 2619944 - Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Isomerase that catalyzes the condensation of two molecules of trans-2%2C3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. The final product is not yet known (By similarity)%3B Belongs to the PhzF family%3B KEGG: hdn:Hden_2074 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02794 BL14DL4_02795 BL14DL4_02795 nagZ nagZ 2620050 2621279 - Beta-N-acetylhexosaminidase KEGG: hhd:HBHAL_2473 beta-N-acetylhexosaminidase gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02795 BL14DL4_02796 BL14DL4_02796 BL14DL4_02796 2621279 2623210 - Beta-N-acetylhexosaminidase Cleaves muropeptides%2C but not peptidoglycan%3B Belongs to the glycosyl hydrolase 3 family%3B KEGG: bli:BL02716 beta-N-acetylhexosaminidase gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02796 BL14DL4_02797 BL14DL4_02797 BL14DL4_02797 2623226 2624572 - N-acetylmuramoyl-L-alanine amidase Belongs to the UPF0214 family%3B KEGG: pat:Patl_4160 N-acetylmuramoyl-L-alanine amidase gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02797 BL14DL4_02798 BL14DL4_02798 BL14DL4_02798 2624640 2626007 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in arbutin%2C cellobiose%2C and salicin transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL02718 PTS system%2C sucrose-specific IIB component gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02798 BL14DL4_02799 BL14DL4_02799 BL14DL4_02799 2626034 2626882 - putative HTH-type transcriptional regulator YbbH Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02799 BL14DL4_02800 BL14DL4_02800 BL14DL4_02800 2626901 2627815 - N-acetylmuramic acid 6-phosphate etherase Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate%2C producing GlcNAc 6- phosphate and D-lactate%3B Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily%3B Contains 1 SIS domain%3B KEGG: bli:BL02720 N-acetylmuramic acid 6-phosphate etherase gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02800 BL14DL4_02801 BL14DL4_02801 BL14DL4_02801 2627990 2628442 - uncharacterized protein gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02801 BL14DL4_02802 BL14DL4_02802 BL14DL4_02802 2628626 2628700 + tRNA-Glu tRNA gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02802 BL14DL4_02803 BL14DL4_02803 BL14DL4_02803 2628851 2628926 + tRNA-Val tRNA gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02803 BL14DL4_02804 BL14DL4_02804 BL14DL4_02804 2628985 2629057 + tRNA-Thr tRNA gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02804 BL14DL4_02805 BL14DL4_02805 BL14DL4_02805 2629066 2629150 + tRNA-Tyr tRNA gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02805 BL14DL4_02806 BL14DL4_02806 BL14DL4_02806 2629155 2629226 + tRNA-Gln tRNA gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02806 BL14DL4_02807 BL14DL4_02807 rocF rocF 2629352 2630266 + Arginase Belongs to the arginase family%3B KEGG: bli:BL02698 arginase gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02807 BL14DL4_02808 BL14DL4_02808 BL14DL4_02808 2630492 2631055 + ECF RNA polymerase sigma factor SigW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02808 BL14DL4_02809 BL14DL4_02809 BL14DL4_02809 2631099 2631689 + Anti-sigma-W factor RsiW Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW%2C and its proteolytic destruction to sigma-W activation (By similarity)%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02809 BL14DL4_02810 BL14DL4_02810 dacA dacA 2631855 2632676 + Diadenylate cyclase KEGG: bsu:BSU01750 diadenylate cyclase gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02810 BL14DL4_02811 BL14DL4_02811 BL14DL4_02811 2632669 2633985 + YbbR-like domain-containing protein YbbR Contains 4 YbbR-like domains gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02811 BL14DL4_02812 BL14DL4_02812 glmM glmM 2634006 2635352 + Phosphoglucosamine mutase Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate%3B Belongs to the phosphohexose mutase family%3B KEGG: scu:SCE1572_24625 phosphoglucosamine mutase gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02812 BL14DL4_02813 BL14DL4_02813 glmS glmS 2635794 2637596 + Glutamine--fructose-6-phosphate transaminase (isomerizing) Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source%3B Contains 1 glutamine amidotransferase type-2 domain%3B Contains 2 SIS domains%3B KEGG: alv:Alvin_0239 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02813 BL14DL4_02814 BL14DL4_02814 BL14DL4_02814 2637787 2638110 + hypothetical protein gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02814 BL14DL4_02815 BL14DL4_02815 BL14DL4_02815 2638253 2638861 - hypothetical protein gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02815 BL14DL4_02816 BL14DL4_02816 BL14DL4_02816 2638842 2639723 - putative ABC transporter ATP-binding protein Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02816 BL14DL4_02817 BL14DL4_02817 BL14DL4_02817 2639723 2640100 - putative HTH-type transcriptional regulator YhdI In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02817 BL14DL4_02818 BL14DL4_02818 BL14DL4_02818 2640281 2640583 + putative HTH-type transcriptional regulator YbzH Contains 1 HTH arsR-type DNA-binding domain gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02818 BL14DL4_02819 BL14DL4_02819 BL14DL4_02819 2640728 2641900 + Putative multidrug resistance protein MdtD Belongs to the major facilitator superfamily. TCR/Tet family gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02819 BL14DL4_02820 BL14DL4_02820 BL14DL4_02820 2642149 2642553 - hypothetical protein gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02820 BL14DL4_02821 BL14DL4_02821 abcA abcA 2642582 2644318 - Xenobiotic-transporting ATPase An efflux transporter able to transport Hoechst 33342%2C ethidium bromide%2C doxorubicin and a number of other drugs in vitro into inside out vesicles. The endogenous substrate is unknown. It has been suggested that NBD dimerization induced by ATP-binding causes a large conformational change responsible for substrate translocation (PubMed:18215075). Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL02726 ATP-binding cassette%2C subfamily B%2C bacterial AbcA/BmrA gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02821 BL14DL4_02822 BL14DL4_02822 BL14DL4_02822 2644513 2645157 + uncharacterized protein gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02822 BL14DL4_02823 BL14DL4_02823 BL14DL4_02823 2645231 2645650 + hypothetical protein gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02823 BL14DL4_02824 BL14DL4_02824 BL14DL4_02824 2645725 2646249 + hypothetical protein gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02824 BL14DL4_02825 BL14DL4_02825 aadK aadK 2646358 2647248 + Aminoglycoside 6-adenylyltransferase To E. faecalis AadE%3B KEGG: bli:BL02710 aminoglycoside 6-adenylyltransferase%3B Nucleotidyltransferases gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02825 BL14DL4_02826 BL14DL4_02826 BL14DL4_02826 2647312 2648259 + hypothetical protein gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02826 BL14DL4_02827 BL14DL4_02827 BL14DL4_02827 2648282 2649001 + (S)-2-haloacid dehalogenase Belongs to the HAD-like hydrolase superfamily. YjjG family%3B KEGG: bli:BL02712 2-haloacid dehalogenase gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02827 BL14DL4_02828 BL14DL4_02828 BL14DL4_02828 2649295 2650665 + putative transporter YbxG Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02828 BL14DL4_02829 BL14DL4_02829 BL14DL4_02829 2651049 2652347 - Mg(2+)/citrate complex secondary transporter Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+)%2C Mn(2+)%2C Co(2+)%2C and Zn(2+). Belongs to the CitM (TC 2. A. 11) transporter family gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02829 BL14DL4_02830 BL14DL4_02830 BL14DL4_02830 2652552 2653511 - UPF0065 protein YflP Belongs to the UPF0065 (bug) family gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02830 BL14DL4_02831 BL14DL4_02831 BL14DL4_02831 2653514 2654194 - putative C4-dicarboxylate response regulator DctR Member of the two-component regulatory system DctS/DctR. Essential for expression of DctP (By similarity)%3B Contains 1 response regulatory domain gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02831 BL14DL4_02832 BL14DL4_02832 citS citS 2654191 2655807 - Histidine kinase Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bld:BLi00225 two-component system%2C CitB family%2C sensor histidine kinase CitS gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02832 BL14DL4_02833 BL14DL4_02833 BL14DL4_02833 2656305 2657201 - HTH-type transcriptional activator AllS Positive regulator essential for the expression of allD operon. Binds to the allD promoter (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02833 BL14DL4_02834 BL14DL4_02834 bacD bacD 2657324 2658541 + L-alanine--L-anticapsin ligase Catalyzes the synthesis of Arg-Xaa dipeptides in an ATP- dependent manner. Has strict specificity toward arginine as the N- terminal substrate%3B Contains 1 ATP-grasp domain%3B KEGG: bpu:BPUM_3423 L-alanine-L-anticapsin ligase gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02834 BL14DL4_02835 BL14DL4_02835 BL14DL4_02835 2658615 2659751 + putative MFS-type transporter YdeE Belongs to the major facilitator superfamily gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02835 BL14DL4_02836 BL14DL4_02836 BL14DL4_02836 2659822 2660070 + Sigma-G-dependent sporulation-specific SASP protein gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02836 BL14DL4_02837 BL14DL4_02837 BL14DL4_02837 2660087 2660278 + uncharacterized protein gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02837 BL14DL4_02838 BL14DL4_02838 BL14DL4_02838 2660399 2660665 - uncharacterized protein gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02838 BL14DL4_02839 BL14DL4_02839 BL14DL4_02839 2660723 2662780 - Spermatoproteinis-associated protein May play a role in fertility regulation gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02839 BL14DL4_02840 BL14DL4_02840 BL14DL4_02840 2663429 2663890 - uncharacterized protein gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02840 BL14DL4_02841 BL14DL4_02841 BL14DL4_02841 2663911 2664096 - uncharacterized protein gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02841 BL14DL4_02842 BL14DL4_02842 BL14DL4_02842 2664394 2664714 - uncharacterized protein gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02842 BL14DL4_02843 BL14DL4_02843 BL14DL4_02843 2664840 2666069 + uncharacterized protein gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02843 BL14DL4_02844 BL14DL4_02844 BL14DL4_02844 2667183 2667356 - Spermatoproteinis-associated protein May play a role in fertility regulation gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02844 BL14DL4_02845 BL14DL4_02845 BL14DL4_02845 2668083 2669366 + putative MFS-type transporter YdeG Belongs to the major facilitator superfamily gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02845 BL14DL4_02846 BL14DL4_02846 chlM chlM 2669391 2670164 - Magnesium protoporphyrin IX methyltransferase KEGG: hmo:HM1_0689 magnesium-protoporphyrin O-methyltransferase gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02846 BL14DL4_02847 BL14DL4_02847 qorB qorB 2670332 2671204 + NAD(P)H dehydrogenase (quinone) Quinone oxidoreductase that may play some additional role beyond quinone reduction. Potential redox sensor protein. Overexpression induces retardation of growth%3B Belongs to the NmrA-type oxidoreductase family%3B KEGG: pfe:PSF113_2585 NAD(P)H dehydrogenase (quinone) gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02847 BL14DL4_02848 BL14DL4_02848 BL14DL4_02848 2671559 2672065 - hypothetical protein gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02848 BL14DL4_02849 BL14DL4_02849 BL14DL4_02849 2672303 2673937 + uncharacterized protein To B. subtilis YqeW gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02849 BL14DL4_02850 BL14DL4_02850 BL14DL4_02850 2674088 2674348 + putative membrane protein YubF gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02850 BL14DL4_02851 BL14DL4_02851 BL14DL4_02851 2674500 2674835 - hypothetical protein gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02851 BL14DL4_02852 BL14DL4_02852 BL14DL4_02852 2674905 2675351 - uncharacterized protein gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02852 BL14DL4_02853 BL14DL4_02853 BL14DL4_02853 2675388 2675855 - uncharacterized protein gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02853 BL14DL4_02854 BL14DL4_02854 BL14DL4_02854 2676169 2676588 - hypothetical protein gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02854 BL14DL4_02855 BL14DL4_02855 BL14DL4_02855 2676585 2677493 - putative transporter YbhF Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02855 BL14DL4_02856 BL14DL4_02856 BL14DL4_02856 2677490 2678326 - putative HTH-type transcriptional regulator YbfI Contains 1 HTH araC/xylS-type DNA-binding domain gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02856 BL14DL4_02857 BL14DL4_02857 BL14DL4_02857 2678442 2678855 + hypothetical protein gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02857 BL14DL4_02858 BL14DL4_02858 BL14DL4_02858 2678917 2679384 + hypothetical protein gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02858 BL14DL4_02859 BL14DL4_02859 BL14DL4_02859 2679519 2680136 - hypothetical protein gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02859 BL14DL4_02860 BL14DL4_02860 ybdH ybdH 2680275 2681330 + Glycerol dehydrogenase Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates%2C such as propan-1%2C2-diol%2C butan-2%2C3-diol%2C ethan-1%2C2-diol%2C and 3-mercapto-1%2C2- dihydroxypropane%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bli:BL00169 uncharacterized oxidoreductase%3B Acting on the CH-OH group of donors gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02860 BL14DL4_02861 BL14DL4_02861 BL14DL4_02861 2681503 2683209 + Methyl-accepting chemotaxis protein Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02861 BL14DL4_02862 BL14DL4_02862 BL14DL4_02862 2683235 2684299 + D-xylose-binding periplasmic protein Involved in the high-affinity D-xylose membrane transport system. Binds with high affinity to xylose. Belongs to the bacterial solute-binding protein 2 family gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02862 BL14DL4_02863 BL14DL4_02863 ppiC ppiC 2684338 2685081 - Peptidylprolyl isomerase KEGG: gpi:GPICK_07635 peptidyl-prolyl cis-trans isomerase C gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02863 BL14DL4_02864 BL14DL4_02864 BL14DL4_02864 2685259 2686023 - hypothetical protein gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02864 BL14DL4_02865 BL14DL4_02865 BL14DL4_02865 2686348 2687235 + Virginiamycin B lyase Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage%2C generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid%3B Belongs to the Vgb family%3B KEGG: bli:BL01635 virginiamycin B lyase%3B Other carbon-oxygen lyases gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02865 BL14DL4_02866 BL14DL4_02866 BL14DL4_02866 2687272 2687652 - uncharacterized protein gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02866 BL14DL4_02867 BL14DL4_02867 BL14DL4_02867 2687679 2689133 - Leu/Val/Ile amino-acid permease Permease for leucine%2C valine and isoleucine. Also transports cysteine%2C methionine%2C phenyalanine%2C tyrosine and tryptophan%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2. A. 3. 10) family gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02867 BL14DL4_02868 BL14DL4_02868 mmuM mmuM 2689133 2690080 - Homocysteine S-methyltransferase Contains 1 Hcy-binding domain%3B KEGG: bli:BL01781 homocysteine S-methyltransferase gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02868 BL14DL4_02869 BL14DL4_02869 chbG chbG 2690290 2691030 + Chitin disaccharide deacetylase Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides%3B Belongs to the YdjC deacetylase family%3B KEGG: dgg:DGI_1411 chitin disaccharide deacetylase gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02869 BL14DL4_02870 BL14DL4_02870 BL14DL4_02870 2691044 2692417 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity). This system may be involved in glucosamine transport%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL01637 PTS system%2C N-acetylglucosamine-specific IIB component gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02870 BL14DL4_02871 BL14DL4_02871 queF queF 2692539 2693315 + PreQ(1) synthase Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain%3B KEGG: llo:LLO_0515 7-cyano-7-deazaguanine reductase gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02871 BL14DL4_02872 BL14DL4_02872 BL14DL4_02872 2693358 2694080 - UPF0702 transmembrane protein YrbG Belongs to the UPF0702 family gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02872 BL14DL4_02873 BL14DL4_02873 BL14DL4_02873 2694068 2694778 - Carbonic anhydrase Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation. Belongs to the gamma-class carbonic anhydrase family gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02873 BL14DL4_02874 BL14DL4_02874 BL14DL4_02874 2695302 2695697 - putative membrane protein YjgA gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02874 BL14DL4_02875 BL14DL4_02875 BL14DL4_02875 2695842 2697272 - putative sodium/glutamine symporter GlnT Probably functions as a sodium/glutamine symporter for glutamine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02875 BL14DL4_02876 BL14DL4_02876 glsA glsA 2697297 2698280 - Glutaminase Belongs to the glutaminase family%3B KEGG: bli:BL01786 glutaminase gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02876 BL14DL4_02877 BL14DL4_02877 ycbA ycbA 2698670 2699998 + Histidine kinase Member of the two-component regulatory system GlnK/GlnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates GlnL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bld:BLi00275 two-component system%2C sensor histidine kinase YcbA gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02877 BL14DL4_02878 BL14DL4_02878 BL14DL4_02878 2700005 2700940 + Transcriptional regulatory protein GlnL Member of the two-component regulatory system GlnL/GlnK that positively regulates the expression of the glsA-glnT operon in response to glutamine. GlnL binds the promoter region of glsA- glnT in vitro%3B Contains 1 response regulatory domain gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02878 BL14DL4_02879 BL14DL4_02879 BL14DL4_02879 2700983 2701519 - Ribosomal-protein-alanine N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL01787 ribosomal-protein-alanine N-acetyltransferase gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02879 BL14DL4_02880 BL14DL4_02880 BL14DL4_02880 2701615 2703414 - Regulatory protein BlaR1 BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis. Belongs to the peptidase M56 family gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02880 BL14DL4_02881 BL14DL4_02881 BL14DL4_02881 2703416 2703802 - Penicillinase repressor Transcriptional repressor that constitutively blocks expression of beta-lactamase. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer. Belongs to the BlaI transcriptional regulatory family gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02881 BL14DL4_02882 BL14DL4_02882 penP penP 2704225 2705148 + Beta-lactamase Belongs to the class-A beta-lactamase family%3B KEGG: bli:BL01642 beta-lactamase class A gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02882 BL14DL4_02883 BL14DL4_02883 BL14DL4_02883 2705493 2707244 + Alkaline phosphatase Belongs to the PhoD family%3B KEGG: bli:BL01643 alkaline phosphatase D gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02883 BL14DL4_02884 BL14DL4_02884 BL14DL4_02884 2707266 2707478 + Sec-independent protein translocase protein TatAd Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for PhoD secretion. The cytosolic fraction of TatAd binds the precursor of PhoD%3B Belongs to the TatA/E family gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02884 BL14DL4_02885 BL14DL4_02885 BL14DL4_02885 2707549 2708283 + Sec-independent protein translocase protein TatCd Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance%3B Belongs to the TatC family gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02885 BL14DL4_02886 BL14DL4_02886 kdgD kdgD 2708479 2709405 + 5-dehydro-4-deoxyglucarate dehydratase Belongs to the DapA family%3B KEGG: bli:BL01645 5-dehydro-4-deoxyglucarate dehydratase gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02886 BL14DL4_02887 BL14DL4_02887 BL14DL4_02887 2709427 2710893 + Aldehyde dehydrogenase (NAD(+)) Oxidizes several aliphatic aldehydes%2C particularly c6- aliphatic aldehyde and hexanal%2C but does not oxidize benzaldehyde. Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL01646 aldehyde dehydrogenase (NAD+) gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02887 BL14DL4_02888 BL14DL4_02888 BL14DL4_02888 2710934 2712310 + putative glucarate transporter Uptake of D-glucarate. Belongs to the major facilitator superfamily. Phthalate permease family gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02888 BL14DL4_02889 BL14DL4_02889 gudD gudD 2712348 2713715 + Glucarate dehydratase Catalyzes the dehydration of glucarate to 5-keto-4- deoxy-D-glucarate (5-kdGluc)%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily%3B KEGG: bli:BL01649 glucarate dehydratase gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02889 BL14DL4_02890 BL14DL4_02890 BL14DL4_02890 2713810 2714523 + putative HTH-type transcriptional regulator YcbG Contains 1 HTH gntR-type DNA-binding domain gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02890 BL14DL4_02891 BL14DL4_02891 garD garD 2714612 2716138 + Galactarate dehydratase Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate%3B Belongs to the UxaA family%3B KEGG: bli:BL01651 galactarate dehydratase gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02891 BL14DL4_02892 BL14DL4_02892 BL14DL4_02892 2716301 2716561 + DNA-binding response regulator MtrA Member of the two-component regulatory system MtrA/MtrB%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02892 BL14DL4_02893 BL14DL4_02893 BL14DL4_02893 2716530 2716994 + putative transcriptional regulatory protein YcbL Member of the two-component regulatory system YcbM/YcbL%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02893 BL14DL4_02894 BL14DL4_02894 BL14DL4_02894 2716996 2717931 + Sensor histidine kinase YcbM Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bcz:BCZK0257 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02894 BL14DL4_02895 BL14DL4_02895 BL14DL4_02895 2718026 2718949 + putative ABC transporter ATP-binding protein YcbN Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02895 BL14DL4_02896 BL14DL4_02896 BL14DL4_02896 2718964 2719647 + uncharacterized protein gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02896 BL14DL4_02897 BL14DL4_02897 BL14DL4_02897 2719663 2720360 + Uncharacterized protein%3B nonfunctional due to frameshift pseudo gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02897 BL14DL4_02898 BL14DL4_02898 BL14DL4_02898 2720456 2721535 + uncharacterized protein gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02898 BL14DL4_02899 BL14DL4_02899 BL14DL4_02899 2721691 2722875 + uncharacterized protein gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02899 BL14DL4_02900 BL14DL4_02900 BL14DL4_02900 2723291 2724202 + uncharacterized protein Belongs to the aminoglycoside phosphotransferase family gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02900 BL14DL4_02901 BL14DL4_02901 BL14DL4_02901 2724236 2724655 - Organic hydroperoxide resistance transcriptional regulator Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02901 BL14DL4_02902 BL14DL4_02902 BL14DL4_02902 2724933 2726444 + Long-chain-fatty-acid--CoA ligase Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bca:BCE_3436 long-chain acyl-CoA synthetase gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02902 BL14DL4_02903 BL14DL4_02903 BL14DL4_02903 2726573 2727787 + Alpha-1-antitrypsin-like protein CM55-MM Protease inhibitor%3B Belongs to the serpin family gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02903 BL14DL4_02904 BL14DL4_02904 BL14DL4_02904 2727898 2728725 + hypothetical protein gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02904 BL14DL4_02905 BL14DL4_02905 BL14DL4_02905 2728789 2729616 + hypothetical protein gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02905 BL14DL4_02906 BL14DL4_02906 BL14DL4_02906 2729746 2730498 + HTH-type transcriptional activator mta Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02906 BL14DL4_02907 BL14DL4_02907 BL14DL4_02907 2730711 2730890 + hypothetical protein gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02907 BL14DL4_02908 BL14DL4_02908 BL14DL4_02908 2730910 2731254 + hypothetical protein gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02908 BL14DL4_02909 BL14DL4_02909 BL14DL4_02909 2731247 2731762 + hypothetical protein gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02909 BL14DL4_02910 BL14DL4_02910 BL14DL4_02910 2732179 2732340 + Tryptophan RNA-binding attenuator protein inhibitory protein gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02910 BL14DL4_02911 BL14DL4_02911 BL14DL4_02911 2732360 2733304 + putative transporter YcbK Belongs to the EamA transporter family%3B Contains 1 EamA domain gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02911 BL14DL4_02912 BL14DL4_02912 BL14DL4_02912 2733357 2733749 - uncharacterized protein gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02912 BL14DL4_02913 BL14DL4_02913 BL14DL4_02913 2733963 2735030 + uncharacterized protein gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02913 BL14DL4_02914 BL14DL4_02914 afuC afuC 2735153 2735872 + Fe(3+)-transporting ATPase Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3. A. 1. 14. 5) family%3B Contains 1 ABC transporter domain%3B KEGG: pkc:PKB_1433 iron(III) transport system ATP-binding protein gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02914 BL14DL4_02915 BL14DL4_02915 BL14DL4_02915 2735869 2736627 + hypothetical protein gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02915 BL14DL4_02916 BL14DL4_02916 BL14DL4_02916 2736629 2737399 + hypothetical protein gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02916 BL14DL4_02917 BL14DL4_02917 BL14DL4_02917 2737421 2738083 + Transcriptional regulatory protein CpxR like protein Member of a two-component regulatory system%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02917 BL14DL4_02918 BL14DL4_02918 BL14DL4_02918 2738074 2739444 + Histidine kinase Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin. SpaK may function as a membrane-associated protein kinase that phosphorylates SpaR in response to environmental signals. Contains 1 histidine kinase domain%3B KEGG: bmq:BMQ_2600 histidine kinase gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02918 BL14DL4_02919 BL14DL4_02919 BL14DL4_02919 2739517 2740401 - HTH-type transcriptional regulator YtlI Positively regulates the expression of ytmI operon in response to the availability of sulfur sources%3B Contains 1 HTH lysR-type DNA-binding domain gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02919 BL14DL4_02920 BL14DL4_02920 BL14DL4_02920 2740511 2740906 + 2-hydroxymuconate tautomerase Belongs to the 4-oxalocrotonate tautomerase family%3B KEGG: bte:BTH_II0588 4-oxalocrotonate tautomerase gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02920 BL14DL4_02921 BL14DL4_02921 BL14DL4_02921 2740910 2741650 + 3-oxoacyl-[acyl-carrier-protein] reductase%3B nonfunctional due to frameshift pseudo gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02921 BL14DL4_02922 BL14DL4_02922 BL14DL4_02922 2741738 2743822 + hypothetical protein gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02922 BL14DL4_02923 BL14DL4_02923 BL14DL4_02923 2743833 2744909 - putative lipoprotein YcdA gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02923 BL14DL4_02924 BL14DL4_02924 BL14DL4_02924 2745525 2746925 - uncharacterized protein To E. coli YfcC and H. influenzae HI_594 gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02924 BL14DL4_02925 BL14DL4_02925 BL14DL4_02925 2747050 2748225 + Peptidase M20 domain-containing protein Belongs to the peptidase M20A family%3B KEGG: tep:TepRe1_0059 amidohydrolase%3B In linear amides gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02925 BL14DL4_02926 BL14DL4_02926 BL14DL4_02926 2748437 2748889 - putative N-acetyltransferase YvbK Probable N-acetyltransferase. Contains 1 N-acetyltransferase domain%3B KEGG: vfi:VF_A0653 null%3B Transferring groups other than amino-acyl groups gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02926 BL14DL4_02927 BL14DL4_02927 BL14DL4_02927 2748989 2750488 + Amidase Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: blh:BaLi_c03450 amidase gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02927 BL14DL4_02928 BL14DL4_02928 BL14DL4_02928 2750511 2752346 - Oligoendopeptidase F like protein Belongs to the peptidase M3B family%3B KEGG: thl:THE_06790 oligoendopeptidase F%3B Metalloendopeptidases gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02928 BL14DL4_02929 BL14DL4_02929 BL14DL4_02929 2752459 2752728 - UPF0410 protein YwzA Belongs to the UPF0410 family gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02929 BL14DL4_02930 BL14DL4_02930 BL14DL4_02930 2752899 2754614 + Serine-type D-Ala-D-Ala carboxypeptidase Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure but its precise function is unknown%3B KEGG: riv:Riv7116_5464 D-alanyl-D-alanine carboxypeptidase gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02930 BL14DL4_02931 BL14DL4_02931 BL14DL4_02931 2754674 2755996 - putative glycolate oxidase iron-sulfur subunit Contains 2 4Fe-4S ferredoxin-type domains gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02931 BL14DL4_02932 BL14DL4_02932 glcD glcD 2755993 2757405 - (S)-2-hydroxy-acid oxidase Belongs to the FAD-binding oxidoreductase/transferase type 4 family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bli:BL01799 glycolate oxidase gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02932 BL14DL4_02933 BL14DL4_02933 BL14DL4_02933 2757529 2757831 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIB type-3 domain%3B KEGG: bli:BL01800 PTS system%2C cellobiose-specific IIB component gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02933 BL14DL4_02934 BL14DL4_02934 BL14DL4_02934 2757828 2758160 - Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in lichenan transport. Contains 1 PTS EIIA type-3 domain%3B KEGG: bli:BL01801 PTS system%2C cellobiose-specific IIA component gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02934 BL14DL4_02935 BL14DL4_02935 BL14DL4_02935 2758177 2759463 - Cellobiose permease IIC component The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in cellobiose transport. Contains 1 PTS EIIC type-3 domain gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02935 BL14DL4_02936 BL14DL4_02936 BL14DL4_02936 2759450 2760784 - 6-phospho-beta-glucosidase Hydrolyzes cellobiose 6'-phosphate into glucose 6- phosphate (Glc6P) and glucose. Belongs to the glycosyl hydrolase 4 family%3B KEGG: hav:AT03_20490 6-phospho-beta-glucosidase gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02936 BL14DL4_02937 BL14DL4_02937 BL14DL4_02937 2760946 2761674 + HTH-type transcriptional regulator GmuR Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan%3B Contains 1 HTH gntR-type DNA-binding domain gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02937 BL14DL4_02938 BL14DL4_02938 BL14DL4_02938 2761679 2762413 + Chitin disaccharide deacetylase Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer%2C the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P%2C the inducer of ChbR and the substrate of ChbF%3B Belongs to the YdjC deacetylase family. ChbG subfamily%3B KEGG: blh:BaLi_c03560 chitin disaccharide deacetylase gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02938 BL14DL4_02939 BL14DL4_02939 BL14DL4_02939 2762826 2764613 + Chitinase Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 fibronectin type-III domains%3B KEGG: bli:BL01685 chitinase gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02939 BL14DL4_02940 BL14DL4_02940 BL14DL4_02940 2764704 2766785 + Chitinase Hydrolyzes chitin oligosaccharide%3B (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5%2C6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin%2C glucosamine oligosaccharides%2C glycoproteins and glycopeptides containing (GlcNAc)2. Belongs to the glycosyl hydrolase 18 family%3B KEGG: bli:BL01686 chitinase gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02940 BL14DL4_02941 BL14DL4_02941 sspA sspA 2766844 2767794 - Glutamyl endopeptidase Specific for hydrolysis of peptide bonds on the carboxyl side of acidic amino acid residues%2C with a strong preference for Glu. Belongs to the peptidase S1B family%3B KEGG: bli:BL01804 glutamyl endopeptidase gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02941 BL14DL4_02942 BL14DL4_02942 BL14DL4_02942 2767966 2768739 + Glucose 1-dehydrogenase (NAD(P)(+)) Involved in the non-phosphorylated metabolic pathway of L-rhamnose catabolism. Catalyzes the oxidation of L-rhamnose to yield L-rhamnono-1%2C4-lactone. It can also oxidize L-lyxose and L- mannose%2C and uses only NADP%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: eta:ETA_30410 glucose 1-dehydrogenase gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02942 BL14DL4_02943 BL14DL4_02943 BL14DL4_02943 2768906 2769616 + hypothetical protein gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02943 BL14DL4_02944 BL14DL4_02944 BL14DL4_02944 2769825 2771222 + uncharacterized protein To B. subtilis YcdC gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02944 BL14DL4_02945 BL14DL4_02945 mpsT mpsT 2771276 2772127 - Thiosulfate sulfurtransferase Contains 2 rhodanese domains%3B KEGG: bli:BL01805 thiosulfate/3-mercaptopyruvate sulfurtransferase gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02945 BL14DL4_02946 BL14DL4_02946 BL14DL4_02946 2772285 2772713 + N-acetylmuramoyl-L-alanine amidase Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination. Belongs to the CwlJ family%3B KEGG: bli:BL01690 N-acetylmuramoyl-L-alanine amidase gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02946 BL14DL4_02947 BL14DL4_02947 BL14DL4_02947 2772760 2773752 - uncharacterized protein To bacterial alkanal monooxygenase alpha and beta chains%3B KEGG: gfo:GFO_3489 null%3B Oxidoreductases gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02947 BL14DL4_02948 BL14DL4_02948 BL14DL4_02948 2774061 2775419 + Peptidoglycan DL-endopeptidase CwlO Shows a cell wall hydrolytic DL-endopeptidase activity%3B Belongs to the peptidase C40 family gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02948 BL14DL4_02949 BL14DL4_02949 BL14DL4_02949 2775471 2776283 - hypothetical protein gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02949 BL14DL4_02950 BL14DL4_02950 BL14DL4_02950 2776280 2777167 - Putative phosphonates utilization ATP-binding protein Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: eco:b1858 zinc transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02950 BL14DL4_02951 BL14DL4_02951 BL14DL4_02951 2777317 2777904 + Fatty acid metabolism regulator protein Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation%2C including acdA%2C fadA%2C fadB%2C fadE%2C fadF%2C fadG%2C fadH%2C fadM%2C fadN%2C lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length%3B Contains 1 HTH tetR-type DNA-binding domain gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02951 BL14DL4_02952 BL14DL4_02952 BL14DL4_02952 2778007 2779902 + hypothetical protein gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02952 BL14DL4_02953 BL14DL4_02953 BL14DL4_02953 2779934 2780416 - hypothetical protein gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02953 BL14DL4_02954 BL14DL4_02954 BL14DL4_02954 2780409 2780972 - Negative transcription regulator PadR Negative transcriptional regulator of padC phenolic acid decarboxylase gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02954 BL14DL4_02955 BL14DL4_02955 BL14DL4_02955 2781289 2781891 + General stress protein 16U Belongs to the CAPAB/TerDEXZ family gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02955 BL14DL4_02956 BL14DL4_02956 BL14DL4_02956 2781920 2782501 + General stress protein 16U Belongs to the CAPAB/TerDEXZ family gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02956 BL14DL4_02957 BL14DL4_02957 BL14DL4_02957 2782577 2783155 + uncharacterized protein Belongs to the CAPAB/TerDEXZ family gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02957 BL14DL4_02958 BL14DL4_02958 BL14DL4_02958 2783221 2783994 + putative membrane protein YceF Belongs to the TerC family gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02958 BL14DL4_02959 BL14DL4_02959 BL14DL4_02959 2784088 2785269 + hypothetical protein gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02959 BL14DL4_02960 BL14DL4_02960 BL14DL4_02960 2785414 2785635 + hypothetical protein gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02960 BL14DL4_02961 BL14DL4_02961 BL14DL4_02961 2785641 2787245 + uncharacterized protein gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02961 BL14DL4_02962 BL14DL4_02962 BL14DL4_02962 2787262 2788356 + uncharacterized protein Belongs to the TelA family gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02962 BL14DL4_02963 BL14DL4_02963 BL14DL4_02963 2788507 2789208 + Cytochrome c-type bioproteinis protein CcdA Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane%2C promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat%3B Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation%3B Belongs to the DsbD family gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02963 BL14DL4_02964 BL14DL4_02964 BL14DL4_02964 2789228 2789914 - hypothetical protein gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02964 BL14DL4_02965 BL14DL4_02965 BL14DL4_02965 2789998 2790738 + HTH-type transcriptional regulator ZntR like protein Transcriptional regulator%3B Contains 1 HTH merR-type DNA-binding domain gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02965 BL14DL4_02966 BL14DL4_02966 BL14DL4_02966 2790838 2792043 - Nitrate transporter May function as a nitrate transporter%3B Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2. A. 1. 8) family gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02966 BL14DL4_02967 BL14DL4_02967 BL14DL4_02967 2792493 2793452 + L-lactate dehydrogenase Belongs to the LDH/MDH superfamily. LDH family%3B KEGG: bli:BL01703 L-lactate dehydrogenase gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02967 BL14DL4_02968 BL14DL4_02968 BL14DL4_02968 2793502 2795124 + L-lactate permease May play a role in L-lactate transport. Belongs to the lactate permease family gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02968 BL14DL4_02969 BL14DL4_02969 BL14DL4_02969 2795231 2795872 + Putative amino acid efflux protein YcgF Belongs to the rht family gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02969 BL14DL4_02970 BL14DL4_02970 BL14DL4_02970 2795873 2797207 - putative transporter YcgH Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02970 BL14DL4_02971 BL14DL4_02971 BL14DL4_02971 2797373 2798191 + NAD(+) synthase Belongs to the NAD synthetase family%3B KEGG: bsu:BSU03130 NAD+ synthase gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02971 BL14DL4_02972 BL14DL4_02972 aroK aroK 2798314 2798847 + Shikimate kinase Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate%3B Belongs to the shikimate kinase family%3B KEGG: rpa:RPA0504 shikimate kinase gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02972 BL14DL4_02973 BL14DL4_02973 BL14DL4_02973 2799139 2799909 + uncharacterized protein gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02973 BL14DL4_02974 BL14DL4_02974 BL14DL4_02974 2800259 2801176 + Proline dehydrogenase Catalyzes the oxidation of L-proline to delta-1- pyrroline-5-carboxylate (P5C)%3B Belongs to the proline dehydrogenase family%3B KEGG: bsl:A7A1_1878 proline dehydrogenase%3B Acting on the CH-NH group of donors gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02974 BL14DL4_02975 BL14DL4_02975 BL14DL4_02975 2801200 2802750 + L-glutamate gamma-semialdehyde dehydrogenase Belongs to the aldehyde dehydrogenase family. RocA subfamily%3B KEGG: bli:BL01710 1-pyrroline-5-carboxylate dehydrogenase gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02975 BL14DL4_02976 BL14DL4_02976 BL14DL4_02976 2802905 2804329 + Sodium/proline symporter Catalyzes the sodium-dependent uptake of extracellular L-proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02976 BL14DL4_02977 BL14DL4_02977 BL14DL4_02977 2804490 2805734 + Proline-responsive transcriptional activator PutR Activates transcription of the putBCP operon. Requires proline as a coactivator%3B Belongs to the CdaR family gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02977 BL14DL4_02978 BL14DL4_02978 BL14DL4_02978 2805772 2806617 - UPF0703 protein YcgQ Belongs to the UPF0703 family gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02978 BL14DL4_02979 BL14DL4_02979 BL14DL4_02979 2806622 2807509 - UPF0718 protein YcgR Belongs to the UPF0718 family gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02979 BL14DL4_02980 BL14DL4_02980 BL14DL4_02980 2807700 2808656 + Cephalosporin-C deacetylase Esterase that removed acetyl groups from a number of O- acetylated small substrates%2C such as acetylated xylose%2C short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages%3B Belongs to the carbohydrate esterase 7 family%3B KEGG: bli:BL01713 cephalosporin-C deacetylase gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02980 BL14DL4_02981 BL14DL4_02981 BL14DL4_02981 2808749 2809171 + hypothetical protein gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02981 BL14DL4_02982 BL14DL4_02982 BL14DL4_02982 2809162 2809503 + hypothetical protein gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02982 BL14DL4_02983 BL14DL4_02983 BL14DL4_02983 2809607 2810167 - hypothetical protein gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02983 BL14DL4_02984 BL14DL4_02984 BL14DL4_02984 2810470 2811153 - putative amino-acid ABC transporter permease protein YckA Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02984 BL14DL4_02985 BL14DL4_02985 BL14DL4_02985 2811165 2812040 - putative ABC transporter extracellular-binding protein YckB Probably part of a binding-protein-dependent transport system. Belongs to the bacterial solute-binding protein 3 family gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02985 BL14DL4_02986 BL14DL4_02986 BL14DL4_02986 2812224 2812775 + Modulator of drug activity B like protein To E. coli MadB and S. pombe SPAC5H10. 05c gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02986 BL14DL4_02987 BL14DL4_02987 BL14DL4_02987 2812872 2813597 + hypothetical protein gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02987 BL14DL4_02988 BL14DL4_02988 BL14DL4_02988 2813667 2815103 + 6-phospho-beta-glucosidase Hydrolyzes p-nitrophenyl beta-D-glucoside%2C p-nitrophenyl beta-D-mannoside%2C p-nitrophenyl beta-D-galactoside%2C p-nitrophenyl beta-D-xyloside%2C p-nitrophenyl beta-D-fucoside%2C p-nitrophenyl beta-L-arabinoside%2C cello-oligosaccharides%2C laminari- oligosaccharides and sophorose%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bli:BL01718 6-phospho-beta-glucosidase gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02988 BL14DL4_02989 BL14DL4_02989 BL14DL4_02989 2815142 2815540 - DNA-entry nuclease inhibitor gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02989 BL14DL4_02990 BL14DL4_02990 BL14DL4_02990 2815558 2816004 - DNA-entry nuclease By degrading DNA that enters the cell%2C plays a role in the competence of cells to be transformed. Degrades both double- stranded%2C linear and covalently closed circular DNA. To B. subtilis NucB gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02990 BL14DL4_02991 BL14DL4_02991 BL14DL4_02991 2816479 2817282 + Non-specific serine/threonine protein kinase Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 1 protein kinase domain%3B KEGG: bli:BL01719 serine/threonine protein kinase%2C bacterial gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02991 BL14DL4_02992 BL14DL4_02992 BL14DL4_02992 2817302 2817805 - Transducer protein Car Mediates chemotaxis towards arginine. Probably transduces the signal to the histidine kinase CheA%3B Contains 1 methyl-accepting transducer domain%3B Contains 1 PAS (PER-ARNT-SIM) domain gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02992 BL14DL4_02993 BL14DL4_02993 BL14DL4_02993 2817802 2818986 - Methyl-accepting chemotaxis protein TlpC Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02993 BL14DL4_02994 BL14DL4_02994 BL14DL4_02994 2819104 2819844 - Ribonuclease YobL Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 449-600) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02994 BL14DL4_02995 BL14DL4_02995 hyuA hyuA 2820248 2822302 + N-methylhydantoinase (ATP-hydrolyzing) Belongs to the oxoprolinase family%3B KEGG: bli:BL01720 N-methylhydantoinase A gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02995 BL14DL4_02996 BL14DL4_02996 hyuB hyuB 2822305 2824299 + N-methylhydantoinase (ATP-hydrolyzing) Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway%3B Belongs to the oxoprolinase family%3B KEGG: bli:BL01721 N-methylhydantoinase B gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02996 BL14DL4_02997 BL14DL4_02997 BL14DL4_02997 2824296 2825384 + hypothetical protein gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02997 BL14DL4_02998 BL14DL4_02998 BL14DL4_02998 2825385 2826512 + Phosphate-transporting ATPase Belongs to the ABC transporter superfamily. MsbA family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: hde:HDEF_2253 phosphate transport system ATP-binding protein gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02998 BL14DL4_02999 BL14DL4_02999 BL14DL4_02999 2826499 2827365 + Inner membrane ABC transporter permease protein Probably part of the binding-protein-dependent transport system YdcSTU%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_02999 BL14DL4_03000 BL14DL4_03000 BL14DL4_03000 2827358 2828170 + Inner membrane ABC transporter permease protein Probably part of the binding-protein-dependent transport system YdcSTU%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03000 BL14DL4_03001 BL14DL4_03001 BL14DL4_03001 2828908 2839665 + Surfactin synthase subunit This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu%2C Glu%2C Asp and Val. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 3 acyl carrier domains gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03001 BL14DL4_03002 BL14DL4_03002 BL14DL4_03002 2839685 2850451 + Bacitracin synthase Induces peptide synthesis%2C activates and incorporates five amino acids%2C forms a thiazoline ring between the first two amino acids and incoporates a D-glutamine in the fourth position. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 5 acyl carrier domains gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03002 BL14DL4_03003 BL14DL4_03003 BL14DL4_03003 2850509 2854357 + Gramicidin S synthase This protein is a multifunctional enzyme%2C able to activate and polymerize the amino acids Pro%2C Val%2C Orn and Leu. Activation sites for these AA consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family%3B Contains 4 acyl carrier domains gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03003 BL14DL4_03004 BL14DL4_03004 BL14DL4_03004 2854361 2855101 + Surfactin synthase thioesterase subunit Probable thioesterase involved in the biosynthesis of surfactin. Belongs to the thioesterase family gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03004 BL14DL4_03005 BL14DL4_03005 BL14DL4_03005 2855148 2856059 - putative transporter YcxC Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03005 BL14DL4_03006 BL14DL4_03006 BL14DL4_03006 2856195 2857544 + putative HTH-type transcriptional regulator YcxD In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03006 BL14DL4_03007 BL14DL4_03007 lys5 lys5 2857556 2858236 - 4'-phosphopantetheinyl transferase May activate the peptidyl carrier protein (PCP) domains of surfactin synthetase SRF1/2/3 and iturin A synthetase%2C by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Required for the coproduction of the lipopeptide antibiotics%2C iturin A and surfactin. Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family%3B KEGG: bli:BL01825 4'-phosphopantetheinyl transferase%3B Transferases for other substituted phosphate groups gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03007 BL14DL4_03008 BL14DL4_03008 BL14DL4_03008 2858306 2859121 + uncharacterized protein gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03008 BL14DL4_03009 BL14DL4_03009 BL14DL4_03009 2859367 2859750 + putative HTH-type transcriptional regulator YdeE Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03009 BL14DL4_03010 BL14DL4_03010 BL14DL4_03010 2860034 2860696 - putative membrane protein YczE gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03010 BL14DL4_03011 BL14DL4_03011 BL14DL4_03011 2860952 2861482 + hypothetical protein gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03011 BL14DL4_03012 BL14DL4_03012 BL14DL4_03012 2861509 2862438 + Aliphatic sulfonates import ATP-binding protein SsuB Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03012 BL14DL4_03013 BL14DL4_03013 BL14DL4_03013 2862419 2863318 + hypothetical protein gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03013 BL14DL4_03014 BL14DL4_03014 BL14DL4_03014 2863337 2863510 + hypothetical protein gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03014 BL14DL4_03015 BL14DL4_03015 BL14DL4_03015 2864012 2865673 + Aromatic-L-amino-acid decarboxylase Catalyzes the production of GABA%3B Belongs to the group II decarboxylase family%3B KEGG: rxy:Rxyl_1038 aromatic-L-amino-acid decarboxylase gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03015 BL14DL4_03016 BL14DL4_03016 BL14DL4_03016 2865688 2867412 + putative methyl-accepting chemotaxis protein Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03016 BL14DL4_03017 BL14DL4_03017 BL14DL4_03017 2867451 2868194 - Galactose/methyl galactoside import ATP-binding protein MglA Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable)%3B Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3. A. 1. 2. 3) family%3B Contains 2 ABC transporter domains gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03017 BL14DL4_03018 BL14DL4_03018 BL14DL4_03018 2868210 2868914 - L-cystine transport system permease protein TcyB Part of the ABC transporter complex TcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03018 BL14DL4_03019 BL14DL4_03019 BL14DL4_03019 2868901 2869707 - L-cystine-binding protein TcyA Part of the ABC transporter complex TcyABC involved in L-cystine import%3B Belongs to the bacterial solute-binding protein 3 family gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03019 BL14DL4_03020 BL14DL4_03020 BL14DL4_03020 2869836 2871248 - Arginine utilization regulatory protein RocR Positive regulator of arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF and probably acts by binding to the corresponding upstream activating sequences%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B Contains 1 sigma-54 factor interaction domain gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03020 BL14DL4_03021 BL14DL4_03021 rocD rocD 2871490 2872692 + Ornithine aminotransferase Catalyzes the interconversion of ornithine to glutamate semialdehyde%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily%3B KEGG: bli:BL01737 ornithine--oxo-acid transaminase gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03021 BL14DL4_03022 BL14DL4_03022 BL14DL4_03022 2872864 2874309 + putative amino acid permease YvbW May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03022 BL14DL4_03023 BL14DL4_03023 BL14DL4_03023 2874302 2875195 + Arginase Belongs to the arginase family%3B KEGG: aka:TKWG_24915 arginase gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03023 BL14DL4_03024 BL14DL4_03024 BL14DL4_03024 2875263 2876135 - HTH-type transcriptional regulator BsdA Could be a positive regulator of bsdBCD expression in response to salicylic acid%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03024 BL14DL4_03025 BL14DL4_03025 ubiX ubiX 2876258 2876827 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C (By similarity). Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions (PubMed:18388975)%3B Belongs to the UbiX/PAD1 family. YclB subfamily%3B KEGG: eas:Entas_1524 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03025 BL14DL4_03026 BL14DL4_03026 ubiD ubiD 2876841 2878262 + 4-hydroxy-3-polyprenylbenzoate decarboxylase Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives%3B Belongs to the UbiD family. YclC subfamily%3B KEGG: sul:SYO3AOP1_0556 4-hydroxy-3-polyprenylbenzoate decarboxylase gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03026 BL14DL4_03027 BL14DL4_03027 BL14DL4_03027 2878282 2878509 + Phenolic acid decarboxylase subunit Part of the BsdBCD complex involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate%2C vanillate and salicylate. Is not active on di- and tri-hydroxybenzoate derivatives gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03027 BL14DL4_03028 BL14DL4_03028 BL14DL4_03028 2878525 2878980 + uncharacterized protein gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03028 BL14DL4_03029 BL14DL4_03029 BL14DL4_03029 2879015 2879461 - hypothetical protein gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03029 BL14DL4_03030 BL14DL4_03030 BL14DL4_03030 2879487 2879828 - hypothetical protein gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03030 BL14DL4_03031 BL14DL4_03031 BL14DL4_03031 2879886 2880332 - hypothetical protein gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03031 BL14DL4_03032 BL14DL4_03032 BL14DL4_03032 2880353 2881033 - hypothetical protein gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03032 BL14DL4_03033 BL14DL4_03033 BL14DL4_03033 2881051 2881308 - hypothetical protein gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03033 BL14DL4_03034 BL14DL4_03034 BL14DL4_03034 2881474 2882277 - hypothetical protein gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03034 BL14DL4_03035 BL14DL4_03035 BL14DL4_03035 2882303 2882644 - hypothetical protein gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03035 BL14DL4_03036 BL14DL4_03036 BL14DL4_03036 2882657 2884282 - Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03036 BL14DL4_03037 BL14DL4_03037 BL14DL4_03037 2884300 2884578 - uncharacterized protein gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03037 BL14DL4_03038 BL14DL4_03038 BL14DL4_03038 2884592 2884975 - uncharacterized protein gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03038 BL14DL4_03039 BL14DL4_03039 BL14DL4_03039 2885477 2886469 + D-allose-binding periplasmic protein Part of the binding-protein-dependent transport system AlsBAC for D-allose%3B Belongs to the bacterial solute-binding protein 2 family gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03039 BL14DL4_03040 BL14DL4_03040 BL14DL4_03040 2886456 2888225 + Histidine kinase Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpB is required for taxis towards asparagine%2C aspartate%2C glutamine%2C and histidine%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain%3B KEGG: bli:BL01744 two-component system%2C sensor histidine kinase YesM gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03040 BL14DL4_03041 BL14DL4_03041 BL14DL4_03041 2888218 2889420 + putative response regulatory protein Probable member of the two-component regulatory system SAB0162c/SAB0161c%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03041 BL14DL4_03042 BL14DL4_03042 BL14DL4_03042 2889548 2890627 + Multiple sugar-binding periplasmic receptor ChvE Required for effective transcriptional induction of the vir genes by monosaccharides in response to plant signals and for normal growth and chemotaxis towards certain sugars. Function as a periplasmic multiple sugar-binding receptor protein. It does not interact with a transport system. Belongs to the bacterial solute-binding protein 2 family gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03042 BL14DL4_03043 BL14DL4_03043 BL14DL4_03043 2890632 2892200 + L-arabinose transport ATP-binding protein AraG Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03043 BL14DL4_03044 BL14DL4_03044 BL14DL4_03044 2892175 2893386 + Xylose transport system permease protein Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03044 BL14DL4_03045 BL14DL4_03045 BL14DL4_03045 2893433 2894701 - putative MFS-type transporter YbfB Belongs to the major facilitator superfamily gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03045 BL14DL4_03046 BL14DL4_03046 yjgM yjgM 2894717 2895634 - Putative HTH-type DNA-binding domain-containing acetyltransferase YbfA Putative DNA-binding acetyltransferase%3B Contains 1 HTH marR-type DNA-binding domain%3B Contains 1 N-acetyltransferase domain%3B KEGG: bfb:VU15_08170 putative acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03046 BL14DL4_03047 BL14DL4_03047 BL14DL4_03047 2895914 2897986 + Beta-galactosidase Belongs to the glycosyl hydrolase 42 family%3B KEGG: bli:BL01749 beta-galactosidase gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03047 BL14DL4_03048 BL14DL4_03048 BL14DL4_03048 2898228 2899373 - 3-phytase Catalyzes the hydrolysis of inorganic orthophosphate from phytate. Only phytate%2C ADP%2C and ATP were hydrolyzed (100%2C 75%2C and 50%25 of the relative activity%2C respectively). Contains 1 BPP (beta-propeller phytase) domain%3B KEGG: bli:BL01844 3-phytase gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03048 BL14DL4_03049 BL14DL4_03049 BL14DL4_03049 2899624 2901114 - putative transporter YclF Belongs to the PTR2/POT transporter (TC 2. A. 17) family gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03049 BL14DL4_03050 BL14DL4_03050 BL14DL4_03050 2901383 2903140 + uncharacterized protein Contains 11 PbH1 repeats gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03050 BL14DL4_03051 BL14DL4_03051 BL14DL4_03051 2903164 2903382 - hypothetical protein gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03051 BL14DL4_03052 BL14DL4_03052 BL14DL4_03052 2903477 2905150 + Spore germination protein KA Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKA family gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03052 BL14DL4_03053 BL14DL4_03053 BL14DL4_03053 2905134 2906357 + Spore germination protein KC Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKC lipoprotein family gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03053 BL14DL4_03054 BL14DL4_03054 BL14DL4_03054 2906382 2907488 + Spore germination protein KB Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2. A. 3. 9) family gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03054 BL14DL4_03055 BL14DL4_03055 BL14DL4_03055 2907640 2908272 + HTH-type transcriptional activator mta Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself%2C ydfK and ymfE%3B Contains 1 HTH merR-type DNA-binding domain gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03055 BL14DL4_03056 BL14DL4_03056 BL14DL4_03056 2908305 2908988 - Spermidine/putrescine import ATP-binding protein PotA Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3. A. 1. 11. 1) family%3B Contains 1 ABC transporter domain gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03056 BL14DL4_03057 BL14DL4_03057 BL14DL4_03057 2909004 2910443 - putative ABC transporter permease YclI Belongs to the ABC-4 integral membrane protein family gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03057 BL14DL4_03058 BL14DL4_03058 BL14DL4_03058 2910661 2911347 + Cell cycle transcriptional regulator CtrA Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle%2C including cell division%2C stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA replication%2C DNA methylation%2C and class II flagellar biogenesis. Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03058 BL14DL4_03059 BL14DL4_03059 BL14DL4_03059 2911337 2912764 + Histidine kinase Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: gst:HW35_03555 two-component system%2C OmpR family%2C sensor histidine kinase ResE gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03059 BL14DL4_03060 BL14DL4_03060 BL14DL4_03060 2912797 2914515 - Methyl-accepting chemotaxis protein McpA Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpA is required for taxis towards glucose and alpha-methylglucoside%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03060 BL14DL4_03061 BL14DL4_03061 BL14DL4_03061 2914651 2916012 - Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 2 ACT domains%3B KEGG: bsu:BSU03790 aspartate kinase gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03061 BL14DL4_03062 BL14DL4_03062 BL14DL4_03062 2916289 2917242 + putative ABC transporter permease protein YclN Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03062 BL14DL4_03063 BL14DL4_03063 BL14DL4_03063 2917232 2918176 + putative ABC transporter permease protein YclO Probably part of an ABC transporter complex. Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03063 BL14DL4_03064 BL14DL4_03064 BL14DL4_03064 2918176 2918934 + Polar-amino-acid-transporting ATPase Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: msu:MS1685 polar amino acid transport system ATP-binding protein gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03064 BL14DL4_03065 BL14DL4_03065 BL14DL4_03065 2918949 2919896 + Putative ABC transporter substrate-binding lipoprotein YhfQ Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03065 BL14DL4_03066 BL14DL4_03066 BL14DL4_03066 2920065 2921486 - MFS antiporter QDR2 MFS antiporter that does not display functional linkage as drug transporter and performs functions that significantly affect biofilm development and virulence. No substrate for transport has been identified yet%2C but plays an important role in the growth in the host%3B Belongs to the major facilitator superfamily. CAR1 family gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03066 BL14DL4_03067 BL14DL4_03067 BL14DL4_03067 2921498 2922385 - putative HTH-type transcriptional regulator YcnC Contains 1 HTH tetR-type DNA-binding domain gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03067 BL14DL4_03068 BL14DL4_03068 BL14DL4_03068 2922480 2923322 - Carboxyvinyl-carboxyphosphonate phosphorylmutase KEGG: sen:SACE_4109 carboxyvinyl-carboxyphosphonate phosphorylmutase gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03068 BL14DL4_03069 BL14DL4_03069 BL14DL4_03069 2923433 2924170 - FMN reductase (NAD(P)H) Reduces FMNH(2) to FMN%2C with NADH or NADPH as reductant. It also reduces nitroaromatic compounds%2C quinones%2C chromates and azo dyes. It could supply the reduced form of FMN to luciferase- like protein and contribute to the degradation of aromatic compounds%3B Belongs to the flavin oxidoreductase frp family%3B KEGG: bsu:BSU03860 FMN reductase (NAD(P)H) gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03069 BL14DL4_03070 BL14DL4_03070 BL14DL4_03070 2924189 2924476 - Putative monooxygenase YcnE Putative monooxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the LsrG family%3B Contains 1 ABM domain gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03070 BL14DL4_03071 BL14DL4_03071 BL14DL4_03071 2924654 2924950 + putative HTH-type transcriptional regulator YczG Contains 1 HTH arsR-type DNA-binding domain gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03071 BL14DL4_03072 BL14DL4_03072 BL14DL4_03072 2925015 2926445 - HTH-type transcriptional regulatory protein GabR Activates the transcription of the gabTD operon. Is also a repressor of its own expression%2C both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma- aminobutyrate%3B In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03072 BL14DL4_03073 BL14DL4_03073 gabT gabT 2926548 2927861 + 4-aminobutyrate--2-oxoglutarate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL01762 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03073 BL14DL4_03074 BL14DL4_03074 BL14DL4_03074 2927895 2929286 + Amino-acid permease RocE Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2. A. 3. 1) family gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03074 BL14DL4_03075 BL14DL4_03075 gabD gabD 2929261 2930655 + Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD%2C but shows considerable activity with NADP (in vitro) (By similarity)%3B Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL01765 succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03075 BL14DL4_03076 BL14DL4_03076 BL14DL4_03076 2930702 2931586 - putative transporter YwfM Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03076 BL14DL4_03077 BL14DL4_03077 BL14DL4_03077 2931751 2932242 + hypothetical protein gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03077 BL14DL4_03078 BL14DL4_03078 BL14DL4_03078 2932290 2932934 - uncharacterized protein gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03078 BL14DL4_03079 BL14DL4_03079 BL14DL4_03079 2932937 2934574 - Copper transport protein YcnJ Involved in uptake of extracellular oxidized copper under copper-limiting conditions%3B In the N-terminal sectio%3B belongs to the CopC family%3B In the C-terminal sectio%3B belongs to the CopD family gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03079 BL14DL4_03080 BL14DL4_03080 BL14DL4_03080 2934603 2935175 - putative HTH-type transcriptional regulator YgbI Contains 1 HTH deoR-type DNA-binding domain gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03080 BL14DL4_03081 BL14DL4_03081 nirB nirB 2935436 2937730 + Nitrite reductase (NADH) Required for nitrate assimilation%3B KEGG: mmt:Metme_3418 nitrite reductase (NADH) large subunit gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03081 BL14DL4_03082 BL14DL4_03082 nasA nasA 2937732 2939891 + Nitrate reductase Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants%2C fungi and bacteria. Belongs to the prokaryotic molybdopterin-containing oxidoreductase family%3B Contains 1 4Fe-4S Mo/W bis-MGD-type domain%3B KEGG: bsu:BSU03310 assimilatory nitrate reductase catalytic subunit gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03082 BL14DL4_03083 BL14DL4_03083 BL14DL4_03083 2940005 2942425 + Nitrite reductase (NADH) Required for nitrite assimilation%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bsu:BSU03300 nitrite reductase (NADH) large subunit gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03083 BL14DL4_03084 BL14DL4_03084 nirD nirD 2942456 2942776 + Nitrite reductase (NADH) Required for nitrite assimilation. Required for activity of the reductase (By similarity)%3B Contains 1 Rieske domain%3B KEGG: bsu:BSU03290 nitrite reductase (NADH) small subunit gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03084 BL14DL4_03085 BL14DL4_03085 BL14DL4_03085 2942894 2944354 + Uroporphyrinogen-III C-methyltransferase Belongs to the precorrin methyltransferase family%3B KEGG: bli:BL01771 uroporphyrinogen III methyltransferase / synthase gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03085 BL14DL4_03086 BL14DL4_03086 BL14DL4_03086 2944380 2945060 - HTH-type transcriptional repressor CsiR Modulates expression of csiD and lhgO in a temporal manner during entry into stationary phase or during the first few hours of carbon starvation%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03086 BL14DL4_03087 BL14DL4_03087 BL14DL4_03087 2945290 2946930 + Sodium-dependent dicarboxylate transporter SdcS Mediates the transport of the dicarboxylates fumarate%2C malate%2C and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient%3B Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. NADC subfamily gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03087 BL14DL4_03088 BL14DL4_03088 BL14DL4_03088 2947018 2947203 + 3-hydroxyacyl-[acyl-carrier-protein] dehydratase Belongs to the thioester dehydratase family. FabZ subfamily%3B KEGG: bamt:AJ82_02350 3-hydroxyacyl-(acyl-carrier-protein) dehydratase gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03088 BL14DL4_03089 BL14DL4_03089 fwdE fwdE 2947457 2947924 + Formylmethanofuran dehydrogenase Hydrolyzes acyl-CoA thioesters (in vitro). Has a preference for substrates with medium chain length (C10-C14). Inactive towards substrates with C18 or C20 aliphatic chains. Its physiological substrate is not known (By similarity)%3B Contains 1 TsaA-like domain%3B KEGG: aar:Acear_0784 formylmethanofuran dehydrogenase subunit E gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03089 BL14DL4_03090 BL14DL4_03090 ulaC ulaC 2948090 2950141 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B KEGG: bcl:ABC0945 PTS system%2C ascorbate-specific IIA component gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03090 BL14DL4_03091 BL14DL4_03091 ulaB ulaB 2950158 2950439 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase KEGG: efe:EFER_0867 PTS system%2C ascorbate-specific IIB component gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03091 BL14DL4_03092 BL14DL4_03092 BL14DL4_03092 2950463 2951836 + Ascorbate-specific permease IIC component UlaA The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active- transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in ascorbate transport (By similarity)%3B Belongs to the UlaA family gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03092 BL14DL4_03093 BL14DL4_03093 BL14DL4_03093 2951851 2952693 + Transketolase Plays an essential role in total transketolase activity and cell proliferation in cancer cell%3B after transfection with anti-TKTL1 siRNA%2C total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis (By similarity)%3B Belongs to the transketolase family%3B KEGG: bli:BL01777 transketolase gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03093 BL14DL4_03094 BL14DL4_03094 BL14DL4_03094 2952690 2953640 + Transketolase Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)%3B Belongs to the transketolase family. DXPS subfamily%3B KEGG: bli:BL05028 transketolase gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03094 BL14DL4_03095 BL14DL4_03095 BL14DL4_03095 2953715 2954470 + Putative phosphatase YcsE Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03095 BL14DL4_03096 BL14DL4_03096 BL14DL4_03096 2954757 2955518 + UPF0271 protein Belongs to the UPF0271 (lamB) family gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03096 BL14DL4_03097 BL14DL4_03097 BL14DL4_03097 2955543 2956754 + putative membrane protein YcsG Belongs to the NRAMP family gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03097 BL14DL4_03098 BL14DL4_03098 BL14DL4_03098 2956751 2957548 + UPF0317 protein Belongs to the UPF0317 family gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03098 BL14DL4_03099 BL14DL4_03099 BL14DL4_03099 2957626 2958360 + Kinase A inhibitor Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction%2C but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is noncompetitive with respect to ATP gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03099 BL14DL4_03100 BL14DL4_03100 BL14DL4_03100 2958357 2959370 + KipI antagonist Counteracts the inhibitory action of KipI on sporulation. May bind to KipI%2C preventing its function as an inhibitor of kinase A gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03100 BL14DL4_03101 BL14DL4_03101 BL14DL4_03101 2959402 2960151 + HTH-type transcriptional regulator KipR Transcriptional repressor of the kip gene-containing operon%3B Contains 1 HTH iclR-type DNA-binding domain%3B Contains 1 iclR-ED (iclR effector binding) domain gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03101 BL14DL4_03102 BL14DL4_03102 BL14DL4_03102 2960240 2960878 + Spore germination lipase LipC Lipase involved in spore germination%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03102 BL14DL4_03103 BL14DL4_03103 mtlA mtlA 2961123 2962547 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi00505 PTS system%2C mannitol-specific IIB component gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03103 BL14DL4_03104 BL14DL4_03104 BL14DL4_03104 2962614 2963054 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: bld:BLi00506 PTS system%2C mannitol-specific IIA component gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03104 BL14DL4_03105 BL14DL4_03105 mtlD mtlD 2963051 2964190 + Mannitol-1-phosphate 5-dehydrogenase Belongs to the mannitol dehydrogenase family%3B KEGG: eco:b3600 mannitol-1-phosphate 5-dehydrogenase gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03105 BL14DL4_03106 BL14DL4_03106 BL14DL4_03106 2964471 2966549 + Transcriptional regulator MtlR Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03106 BL14DL4_03107 BL14DL4_03107 BL14DL4_03107 2966662 2967531 + General stress protein 39 Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02817 null%3B Oxidoreductases gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03107 BL14DL4_03108 BL14DL4_03108 BL14DL4_03108 2967547 2968050 + putative D-lyxose ketol-isomerase Belongs to the D-lyxose ketol-isomerase family gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03108 BL14DL4_03109 BL14DL4_03109 BL14DL4_03109 2968067 2968450 - hypothetical protein gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03109 BL14DL4_03110 BL14DL4_03110 BL14DL4_03110 2968536 2968958 + General stress protein gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03110 BL14DL4_03111 BL14DL4_03111 BL14DL4_03111 2969411 2970220 + uncharacterized protein gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03111 BL14DL4_03112 BL14DL4_03112 BL14DL4_03112 2970385 2971326 + Regulatory protein MsrR Involved in SarA attenuation. Affects resistance to oxacillin and teicoplanin%2C as well as the synthesis of virulence factors%3B Belongs to the LytR/CpsA/Psr regulatory protein family gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03112 BL14DL4_03113 BL14DL4_03113 BL14DL4_03113 2971358 2971651 - putative membrane protein YdzA gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03113 BL14DL4_03114 BL14DL4_03114 BL14DL4_03114 2971735 2972145 - hypothetical protein gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03114 BL14DL4_03115 BL14DL4_03115 BL14DL4_03115 2972263 2972691 + HTH-type transcriptional regulator LrpA Negative regulation of glyA transcription and kinB- dependent sporulation%3B Contains 1 HTH asnC-type DNA-binding domain gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03115 BL14DL4_03116 BL14DL4_03116 topB topB 2972732 2974948 + DNA topoisomerase Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bld:BLi00518 DNA topoisomerase III gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03116 BL14DL4_03117 BL14DL4_03117 BL14DL4_03117 2975636 2977456 + putative amino acid permease YdaO Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03117 BL14DL4_03118 BL14DL4_03118 poxL poxL 2977565 2979286 + Pyruvate oxidase Important for the aerobic growth. Decarboxylates pyruvate in four steps. The energy released is partially stored in acetyl phosphate. Belongs to the TPP enzyme family%3B KEGG: bli:BL00146 pyruvate oxidase gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03118 BL14DL4_03119 BL14DL4_03119 BL14DL4_03119 2979427 2980038 + GlcNAc-binding protein Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin%3B Belongs to the GbpA family%3B Contains 1 chitin-binding type-3 domain%3B Contains 1 chitin-binding type-4 domain gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03119 BL14DL4_03120 BL14DL4_03120 BL14DL4_03120 2980162 2980413 - putative membrane protein YdzK gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03120 BL14DL4_03121 BL14DL4_03121 rimL rimL 2980485 2981036 - Putative ribosomal N-acetyltransferase YdaF Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00141 ribosomal-protein-serine acetyltransferase%3B Transferring groups other than amino-acyl groups gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03121 BL14DL4_03122 BL14DL4_03122 BL14DL4_03122 2981091 2982371 - Divalent metal cation transporter MntH H(+)-stimulated%2C divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium%2C cobalt%2C copper and zinc%2C but not iron. May be the predominant transporter of manganese during logarithmic phase growth%3B Belongs to the NRAMP family gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03122 BL14DL4_03123 BL14DL4_03123 BL14DL4_03123 2982554 2982802 - UPF0410 protein YdaS Belongs to the UPF0410 family gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03123 BL14DL4_03124 BL14DL4_03124 BL14DL4_03124 2982898 2984319 - Aspartate ammonia-lyase Belongs to the class-II fumarase/aspartase family. Aspartase subfamily%3B KEGG: bli:BL02922 aspartate ammonia-lyase gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03124 BL14DL4_03125 BL14DL4_03125 BL14DL4_03125 2984628 2985812 + putative UDP-glucosyltransferase YdhE Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03125 BL14DL4_03126 BL14DL4_03126 BL14DL4_03126 2985838 2986284 - uncharacterized protein gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03126 BL14DL4_03127 BL14DL4_03127 BL14DL4_03127 2986403 2987227 + uncharacterized protein gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03127 BL14DL4_03128 BL14DL4_03128 BL14DL4_03128 2987267 2988556 - Malate-2H(+)/Na(+)-lactate antiporter Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport%2C in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force. Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03128 BL14DL4_03129 BL14DL4_03129 BL14DL4_03129 2988685 2989401 + uncharacterized protein Belongs to the SchB/CurC family gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03129 BL14DL4_03130 BL14DL4_03130 BL14DL4_03130 2989476 2989916 + Glucose starvation-inducible protein gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03130 BL14DL4_03131 BL14DL4_03131 BL14DL4_03131 2990138 2991178 + UPF0118 membrane protein YdbI Belongs to the UPF0118 (PerM) family gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03131 BL14DL4_03132 BL14DL4_03132 BL14DL4_03132 2991466 2992710 + C4-dicarboxylate transport protein Responsible for the transport of dicarboxylates such as succinate%2C fumarate%2C and malate from the periplasm across the membrane%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03132 BL14DL4_03133 BL14DL4_03133 BL14DL4_03133 2992780 2993706 + Zinc import ATP-binding protein ZnuC Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03133 BL14DL4_03134 BL14DL4_03134 BL14DL4_03134 2993699 2994466 + putative membrane protein YdbK gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03134 BL14DL4_03135 BL14DL4_03135 BL14DL4_03135 2994566 2994922 + uncharacterized protein gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03135 BL14DL4_03136 BL14DL4_03136 BL14DL4_03136 2995047 2996195 + Medium-chain acyl-CoA dehydrogenase Belongs to the acyl-CoA dehydrogenase family%3B KEGG: bcz:BCZK2818 acyl-CoA dehydrogenase gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03136 BL14DL4_03137 BL14DL4_03137 BL14DL4_03137 2996269 2996424 - uncharacterized protein gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03137 BL14DL4_03138 BL14DL4_03138 BL14DL4_03138 2996427 2996585 - hypothetical protein gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03138 BL14DL4_03139 BL14DL4_03139 BL14DL4_03139 2997001 2997321 - Thioredoxin Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03139 BL14DL4_03140 BL14DL4_03140 BL14DL4_03140 2997482 2998567 + D-alanine--D-alanine ligase Cell wall formation%3B Belongs to the D-alanine--D-alanine ligase family%3B Contains 1 ATP-grasp domain%3B KEGG: bli:BL02193 D-alanine-D-alanine ligase gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03140 BL14DL4_03141 BL14DL4_03141 murF murF 2998600 3000075 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide%2C the precursor of murein%3B Belongs to the MurCDEF family. MurF subfamily%3B KEGG: bld:BLi00544 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03141 BL14DL4_03142 BL14DL4_03142 BL14DL4_03142 3000135 3000851 + Carboxylesterase KEGG: paa:Paes_2227 carboxylesterase gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03142 BL14DL4_03143 BL14DL4_03143 deaD deaD 3001202 3002665 + RNA helicase DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions%2C has RNA- dependent ATPase activity%3B Belongs to the DEAD box helicase family. CshA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU04580 ATP-dependent RNA helicase DeaD gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03143 BL14DL4_03144 BL14DL4_03144 BL14DL4_03144 3002779 3003258 + UPF0699 transmembrane protein YdbS Belongs to the UPF0699 family gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03144 BL14DL4_03145 BL14DL4_03145 BL14DL4_03145 3003248 3004729 + UPF0699 transmembrane protein YdbT Belongs to the UPF0699 family gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03145 BL14DL4_03146 BL14DL4_03146 BL14DL4_03146 3004726 3005325 - Putative rhomboid protease YdcA Belongs to the peptidase S54 family gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03146 BL14DL4_03147 BL14DL4_03147 BL14DL4_03147 3005620 3006627 + Sporulation protein YdcC required for efficient sporulation gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03147 BL14DL4_03148 BL14DL4_03148 BL14DL4_03148 3006849 3008021 + Alanine racemase Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids%3B Belongs to the alanine racemase family%3B KEGG: bld:BLi00551 alanine racemase gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03148 BL14DL4_03149 BL14DL4_03149 BL14DL4_03149 3008133 3008414 + Antitoxin EndoAI Antitoxin component of a type II toxin-antitoxin (TA) module. Antitoxin that directly inhibits activity of EndoA in vitro. Upon expression in E. coli counteracts inhibitory effect of endoribonuclease EndoA. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the MazE/EndoAI family gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03149 BL14DL4_03150 BL14DL4_03150 mazF mazF 3008419 3008769 + Endoribonuclease EndoA Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences%2C cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E. coli)%2C probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E. coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662)%3B Belongs to the PemK/MazF family%3B KEGG: bsu:BSU04660 mRNA interferase MazF%3B Acting on ester bonds gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03150 BL14DL4_03151 BL14DL4_03151 BL14DL4_03151 3008887 3009714 + RsbT co-antagonist protein RsbRA Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro. One of 4 functionally non-identical RsbR paralogs%2C it functions in the environmental signaling branch of the general stress response. Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU. Contains 1 STAS domain gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03151 BL14DL4_03152 BL14DL4_03152 BL14DL4_03152 3009718 3010083 + RsbT antagonist protein RsbS Negative regulator of sigma-B activity. Non- phosphorylated RsbS binds to RsbT%2C preventing its association with RsbU. Requires any one of RsbRA%2C RsbRB%2C RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated%2C they release RsbT%2C which can then bind and activate RsbU%3B Contains 1 STAS domain gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03152 BL14DL4_03153 BL14DL4_03153 rsbT rsbT 3010086 3010487 + Non-specific serine/threonine protein kinase Provides the crucial link between the upstream module (communication of environmental stress) and the downstream module (integration of the environmental signals with signals of energy stress) that compose the signal transduction pathway controlling the sigma-B factor. Phosphorylates and inactivates its specific antagonist protein RsbS thanks to its serine kinase activity. Upon phosphorylation of RsbS%2C RsbT is released to stimulate RsbU%2C a PP2C phosphatase%2C thereby initiating the signaling cascade that ultimately activates sigma-B. The activity of the RsbU phosphatase may be stimulated by a long-lived interaction with RsbT and the serine kinase function of RsbT is not required to directly modify RsbU. Also phosphorylates RsbR thanks to its threonine kinase activity%2C preventing it to phosphorylate RsbT%3B KEGG: bsu:BSU04690 serine/threonine-protein kinase RsbT gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03153 BL14DL4_03154 BL14DL4_03154 BL14DL4_03154 3010498 3011505 + Phosphoserine phosphatase RsbU Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module%3B Contains 1 PPM-type phosphatase domain gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03154 BL14DL4_03155 BL14DL4_03155 BL14DL4_03155 3011564 3011890 + Anti-sigma-B factor antagonist Positive regulator of sigma-B activity. Non- phosphorylated RsbV binds to RsbW%2C preventing its association with sigma-B. When phosphorylated%2C releases RsbW%2C which is then free to complex with and inactivate sigma-B (By similarity)%3B Belongs to the anti-sigma-factor antagonist family%3B Contains 1 STAS domain gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03155 BL14DL4_03156 BL14DL4_03156 rsbW rsbW 3011890 3012375 + Non-specific serine/threonine protein kinase Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein%2C RsbV. Upon phosphorylation of RsbV%2C RsbW is released and binds to sigma-B%2C thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)%3B Belongs to the anti-sigma-factor family%3B KEGG: bli:BL02207 serine/threonine-protein kinase RsbW gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03156 BL14DL4_03157 BL14DL4_03157 BL14DL4_03157 3012338 3013132 + RNA polymerase sigma-B factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulatio%3B rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation. May play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions. Positively regulates expression of its own operon. Belongs to the sigma-70 factor family. SigB subfamily gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03157 BL14DL4_03158 BL14DL4_03158 rsbX rsbX 3013129 3013728 + Phosphoserine phosphatase Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bli:BL02209 negative regulator of sigma-B (phosphoserine phosphatase) gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03158 BL14DL4_03159 BL14DL4_03159 BL14DL4_03159 3013806 3015968 + uncharacterized protein Contains 1 S1 motif domain gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03159 BL14DL4_03160 BL14DL4_03160 BL14DL4_03160 3016018 3016575 - putative HTH-type transcriptional regulator YxbF Contains 2 HTH tetR-type DNA-binding domains gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03160 BL14DL4_03161 BL14DL4_03161 BL14DL4_03161 3016932 3020051 + Putative membrane protein YdgH Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. MmpL subfamily gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03161 BL14DL4_03162 BL14DL4_03162 BL14DL4_03162 3020441 3020902 + Protein SprT-like Belongs to the SprT family%3B Contains 1 SprT-like domain gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03162 BL14DL4_03163 BL14DL4_03163 BL14DL4_03163 3021019 3021093 + tRNA-Asn tRNA gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03163 BL14DL4_03164 BL14DL4_03164 BL14DL4_03164 3021096 3021186 + tRNA-Ser tRNA gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03164 BL14DL4_03165 BL14DL4_03165 BL14DL4_03165 3021215 3021286 + tRNA-Glu tRNA gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03165 BL14DL4_03166 BL14DL4_03166 BL14DL4_03166 3021299 3021373 + tRNA-Gln tRNA gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03166 BL14DL4_03167 BL14DL4_03167 BL14DL4_03167 3021382 3021457 + tRNA-Lys tRNA gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03167 BL14DL4_03168 BL14DL4_03168 BL14DL4_03168 3021470 3021552 + tRNA-Leu tRNA gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03168 BL14DL4_03169 BL14DL4_03169 BL14DL4_03169 3021573 3021655 + tRNA-Leu tRNA gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03169 BL14DL4_03170 BL14DL4_03170 BL14DL4_03170 3022045 3022395 - hypothetical protein gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03170 BL14DL4_03171 BL14DL4_03171 BL14DL4_03171 3022385 3022624 - putative HTH-type transcriptional regulator Contains 1 HTH cro/C1-type DNA-binding domain gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03171 BL14DL4_03172 BL14DL4_03172 BL14DL4_03172 3023599 3023624 - Fatty acid desaturase%3B nonfunctional due to frameshift pseudo gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03172 BL14DL4_03173 BL14DL4_03173 BL14DL4_03173 3024863 3025066 + Cold shock protein Contains 1 CSD (cold-shock) domain gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03173 BL14DL4_03174 BL14DL4_03174 mecR mecR 3025322 3026308 - Trans-2-enoyl-CoA reductase (NADPH) Oxidoreductase with a preference for short and medium chain substrates%2C including trans-2-hexenoyl-CoA (C6)%2C trans-2- decenoyl-CoA (C10)%2C and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis (By similarity)%3B Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily%3B KEGG: tsp:Tsp_07030 mitochondrial trans-2-enoyl-CoA reductase gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03174 BL14DL4_03175 BL14DL4_03175 BL14DL4_03175 3026368 3026679 - hypothetical protein gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03175 BL14DL4_03176 BL14DL4_03176 BL14DL4_03176 3026676 3027281 - uncharacterized protein gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03176 BL14DL4_03177 BL14DL4_03177 BL14DL4_03177 3027391 3027846 + putative HTH-type transcriptional regulator YybA Contains 1 HTH marR-type DNA-binding domain gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03177 BL14DL4_03178 BL14DL4_03178 BL14DL4_03178 3027871 3028389 + Spermidine/spermine N(1)-acetyltransferase Involved in the protection against polyamine toxicity by regulating their concentration. Also could be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase%2C levansucrase and alkaline phosphatase. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It possesses N1- acetyltransferase activity toward polyamine substrates including spermidine%2C spermine%2C aminopropylcadaverine%2C norspermidine%2C homospermidine%2C N(8)-acetylspermidine%2C diaminopropane and agmatine%3B Contains 1 N-acetyltransferase domain%3B KEGG: gfo:GFO_2080 null%3B Transferring groups other than amino-acyl groups gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03178 BL14DL4_03179 BL14DL4_03179 BL14DL4_03179 3028411 3029028 + Protease synthase and sporulation protein PAI Involved in the reduction of extracellular and cell- associated protease levels%2C as well as in the reduced levels of alpha-amylase%2C levansucrase%2C alkaline phosphatase and sporulation inhibition%2C when present in high copy number. Belongs to the PaiB family gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03179 BL14DL4_03180 BL14DL4_03180 BL14DL4_03180 3029427 3030341 - Arginase KEGG: xfa:XF1250 arginase gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03180 BL14DL4_03181 BL14DL4_03181 BL14DL4_03181 3030447 3030782 + putative HTH-type transcriptional regulator Contains 1 HTH hxlR-type DNA-binding domain gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03181 BL14DL4_03182 BL14DL4_03182 BL14DL4_03182 3031121 3031993 + UPF0750 membrane protein YdeO Belongs to the UPF0750 family gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03182 BL14DL4_03183 BL14DL4_03183 BL14DL4_03183 3032092 3032541 - Cysteine/O-acetylserine efflux protein Exporter of O-acetylserine (OAS) and cysteine%3B Belongs to the rht family gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03183 BL14DL4_03184 BL14DL4_03184 BL14DL4_03184 3032803 3033684 + HTH-type transcriptional regulator SoxR Transcriptional repressor of soxA gene expression. Contains 1 HTH lysR-type DNA-binding domain gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03184 BL14DL4_03185 BL14DL4_03185 BL14DL4_03185 3033766 3033987 + hypothetical protein gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03185 BL14DL4_03186 BL14DL4_03186 BL14DL4_03186 3034168 3035394 + hypothetical protein gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03186 BL14DL4_03187 BL14DL4_03187 BL14DL4_03187 3035490 3036272 - hypothetical protein gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03187 BL14DL4_03188 BL14DL4_03188 BL14DL4_03188 3036398 3037780 - putative transporter YdgF Probable amino-acid or metabolite transport protein. Belongs to the amino acid-polyamine-organocation (APC) superfamily gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03188 BL14DL4_03189 BL14DL4_03189 BL14DL4_03189 3038182 3038817 + hypothetical protein gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03189 BL14DL4_03190 BL14DL4_03190 BL14DL4_03190 3039010 3039645 + hypothetical protein gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03190 BL14DL4_03191 BL14DL4_03191 BL14DL4_03191 3039987 3040484 + RNA polymerase sigma factor SigV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin%2C paraquat and tellurite%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03191 BL14DL4_03192 BL14DL4_03192 BL14DL4_03192 3040484 3041344 + Anti-sigma-V factor RsiV Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03192 BL14DL4_03193 BL14DL4_03193 BL14DL4_03193 3041575 3043455 + Putative peptidoglycan O-acetyltransferase YrhL Belongs to the acyltransferase 3 family%3B KEGG: mtu:Rv0111 null%3B Transferring groups other than amino-acyl groups gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03193 BL14DL4_03194 BL14DL4_03194 BL14DL4_03194 3043680 3044849 + Bicyclomycin resistance protein Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase%3B Belongs to the major facilitator superfamily. Bcr/CmlA family gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03194 BL14DL4_03195 BL14DL4_03195 BL14DL4_03195 3044889 3047984 - Histidine kinase Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB%2C probably in response to environmental signals. Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: win:WPG_3498 two-component system%2C OmpR family%2C phosphate regulon sensor histidine kinase PhoR gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03195 BL14DL4_03196 BL14DL4_03196 BL14DL4_03196 3048159 3049235 + Sensory transduction protein LytR Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis and cell wall metabolism. Regulates the activity of the cell wall-associated murein hydrolase through regulation of lrgA and lrgB (By similarity)%3B Contains 1 HTH LytTR-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03196 BL14DL4_03197 BL14DL4_03197 BL14DL4_03197 3049533 3055460 + hypothetical protein gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03197 BL14DL4_03198 BL14DL4_03198 BL14DL4_03198 3055527 3056159 + Sortase A Belongs to the peptidase C60 family%3B KEGG: bli:BL00120 sortase A gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03198 BL14DL4_03199 BL14DL4_03199 BL14DL4_03199 3056735 3058156 + Major myo-inositol transporter IolT Major myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03199 BL14DL4_03200 BL14DL4_03200 BL14DL4_03200 3058754 3058830 + tRNA-Arg tRNA gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03200 BL14DL4_03201 BL14DL4_03201 BL14DL4_03201 3058843 3058916 + tRNA-Gly tRNA gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03201 BL14DL4_03202 BL14DL4_03202 BL14DL4_03202 3059074 3060623 + 16S ribosomal RNA rRNA gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03202 BL14DL4_03203 BL14DL4_03203 BL14DL4_03203 3060798 3063728 + 23S ribosomal RNA rRNA gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03203 BL14DL4_03204 BL14DL4_03204 BL14DL4_03204 3063861 3063976 + 5S ribosomal RNA rRNA gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03204 BL14DL4_03205 BL14DL4_03205 BL14DL4_03205 3063989 3064065 + tRNA-Met tRNA gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03205 BL14DL4_03206 BL14DL4_03206 BL14DL4_03206 3064107 3064183 + tRNA-Asp tRNA gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03206 BL14DL4_03207 BL14DL4_03207 thiL thiL 3064378 3065361 + Thiamine-phosphate kinase Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP)%2C the active form of vitamin B1%3B Belongs to the thiamine-monophosphate kinase family%3B KEGG: gsb:GSUB_15825 thiamine-monophosphate kinase gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03207 BL14DL4_03208 BL14DL4_03208 BL14DL4_03208 3065358 3065846 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro%2C which is modulated by the oligomeric status of the protein%3B Belongs to the TsaE family gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03208 BL14DL4_03209 BL14DL4_03209 BL14DL4_03209 3065827 3066516 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaD and Tsa%3B this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway%2C possibly in regulating the core enzymatic function of TsaD%3B Belongs to the KAE1 / TsaD family. TsaB subfamily gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03209 BL14DL4_03210 BL14DL4_03210 rimI rimI 3066541 3066987 + Ribosomal-protein-alanine N-acetyltransferase This enzyme acetylates the N-terminal alanine of ribosomal protein S18%3B Belongs to the acetyltransferase family. RimI subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00844 ribosomal-protein-alanine N-acetyltransferase gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03210 BL14DL4_03211 BL14DL4_03211 kae1 kae1 3066977 3068002 + N(6)-L-threonylcarbamoyladenine synthase Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37%2C together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction%3B Belongs to the KAE1 / TsaD family%3B KEGG: bli:BL00845 N6-L-threonylcarbamoyladenine synthase gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03211 BL14DL4_03212 BL14DL4_03212 BL14DL4_03212 3068242 3070167 - Iron-chelate-transporting ATPase Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily%3B Contains 2 ABC transporter domains%3B KEGG: yee:YE5303_30631 iron complex transport system ATP-binding protein gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03212 BL14DL4_03213 BL14DL4_03213 moaC moaC 3070314 3070820 + Cyclic pyranopterin phosphate synthase Together with MoaA%2C is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z)%3B Belongs to the MoaC family%3B KEGG: spoi:IMCC21906_01961 cyclic pyranopterin phosphate synthase gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03213 BL14DL4_03214 BL14DL4_03214 BL14DL4_03214 3070824 3071471 + Redox-sensing transcriptional repressor Rex Modulates transcription in response to changes in cellular NADH/NAD(+) redox state%3B Belongs to the transcriptional regulatory Rex family gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03214 BL14DL4_03215 BL14DL4_03215 BL14DL4_03215 3071514 3071693 + Sec-independent protein translocase protein TatA Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system%3B Belongs to the TatA/E family gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03215 BL14DL4_03216 BL14DL4_03216 BL14DL4_03216 3071700 3072476 + Sec-independent protein translocase protein TatC Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes%3B Belongs to the TatC family gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03216 BL14DL4_03217 BL14DL4_03217 BL14DL4_03217 3072522 3072716 - putative lipoprotein YdiK gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03217 BL14DL4_03218 BL14DL4_03218 BL14DL4_03218 3072713 3073447 - Putative membrane peptidase YdiL May function as endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine%2C A is an aliphatic amino acid and X is any amino acid%3B Belongs to the peptidase U48 family gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03218 BL14DL4_03219 BL14DL4_03219 BL14DL4_03219 3073673 3073957 + 10 kDa chaperonin Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter%3B Belongs to the GroES chaperonin family gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03219 BL14DL4_03220 BL14DL4_03220 BL14DL4_03220 3074002 3075636 + 60 kDa chaperonin Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions%3B Belongs to the chaperonin (HSP60) family gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03220 BL14DL4_03221 BL14DL4_03221 BL14DL4_03221 3075715 3075855 - hypothetical protein gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03221 BL14DL4_03222 BL14DL4_03222 BL14DL4_03222 3076268 3076504 - hypothetical protein gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03222 BL14DL4_03223 BL14DL4_03223 BL14DL4_03223 3076737 3077078 - hypothetical protein gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03223 BL14DL4_03224 BL14DL4_03224 BL14DL4_03224 3077513 3077749 - hypothetical protein gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03224 BL14DL4_03225 BL14DL4_03225 BL14DL4_03225 3078534 3078668 + hypothetical protein gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03225 BL14DL4_03226 BL14DL4_03226 BL14DL4_03226 3078885 3079802 + uncharacterized protein gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03226 BL14DL4_03227 BL14DL4_03227 BL14DL4_03227 3079920 3080369 + uncharacterized protein gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03227 BL14DL4_03228 BL14DL4_03228 BL14DL4_03228 3080593 3081054 + hypothetical protein gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03228 BL14DL4_03229 BL14DL4_03229 BL14DL4_03229 3081119 3081793 - Putative SOS response-associated peptidase YoaM Belongs to the SOS response-associated peptidase family gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03229 BL14DL4_03230 BL14DL4_03230 BL14DL4_03230 3082225 3082839 + putative HTH-type transcriptional regulator YerO Contains 1 HTH tetR-type DNA-binding domain gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03230 BL14DL4_03231 BL14DL4_03231 BL14DL4_03231 3082855 3085476 + Pyruvate%2C water dikinase Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate%3B Belongs to the PEP-utilizing enzyme family%3B KEGG: bli:BL01065 pyruvate%2C water dikinase gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03231 BL14DL4_03232 BL14DL4_03232 BL14DL4_03232 3085504 3085788 - uncharacterized protein gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03232 BL14DL4_03233 BL14DL4_03233 BL14DL4_03233 3085854 3086216 - DNA-3-methyladenine glycosylase II To M. tuberculosis Rv3073c%3B KEGG: btp:D805_0940 DNA-3-methyladenine glycosylase gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03233 BL14DL4_03234 BL14DL4_03234 dltE dltE 3086300 3087064 - putative oxidoreductase DltE Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: enr:H650_10080 uncharacterized oxidoreductase%3B Oxidoreductases gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03234 BL14DL4_03235 BL14DL4_03235 BL14DL4_03235 3087216 3088688 + Para-nitrobenzyl esterase Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol. Belongs to the type-B carboxylesterase/lipase family%3B KEGG: bli:BL01300 para-nitrobenzyl esterase%3B Carboxylic ester hydrolases gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03235 BL14DL4_03236 BL14DL4_03236 BL14DL4_03236 3088713 3089990 - Minor myo-inositol transporter IolF Minor myo-inositol uptake transporter%3B Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03236 BL14DL4_03237 BL14DL4_03237 BL14DL4_03237 3090360 3091040 + Phage shock protein The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspA negatively regulates expression of the pspABCDE promoter and of pspG through negative regulation of the psp-specific transcriptional activator PspF. Is also required for membrane integrity%2C efficient translocation and maintenance of the proton motive force (By similarity)%3B Belongs to the PspA/IM30 family gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03237 BL14DL4_03238 BL14DL4_03238 BL14DL4_03238 3091075 3092100 + uncharacterized protein gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03238 BL14DL4_03239 BL14DL4_03239 BL14DL4_03239 3092100 3092867 + UPF0603 protein YdjH Belongs to the UPF0603 family gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03239 BL14DL4_03240 BL14DL4_03240 BL14DL4_03240 3092889 3093863 + uncharacterized protein gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03240 BL14DL4_03241 BL14DL4_03241 BL14DL4_03241 3094123 3095178 + uncharacterized protein Belongs to the bacterial luciferase oxidoreductase family%3B KEGG: ret:RHE_CH03117 null%3B Oxidoreductases gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03241 BL14DL4_03242 BL14DL4_03242 BL14DL4_03242 3095211 3096038 - Cadmium-exporting ATPase KEGG: cau:Caur_3747 Cd2+/Zn2+-exporting ATPase gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03242 BL14DL4_03243 BL14DL4_03243 BL14DL4_03243 3096186 3096818 + putative membrane protein YrhP Belongs to the rht family gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03243 BL14DL4_03244 BL14DL4_03244 BL14DL4_03244 3097013 3097657 + hypothetical protein gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03244 BL14DL4_03245 BL14DL4_03245 BL14DL4_03245 3097673 3098830 + Putative lipid II flippase Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03245 BL14DL4_03246 BL14DL4_03246 BL14DL4_03246 3098827 3099975 + Putative lipid II flippase FtsW Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03246 BL14DL4_03247 BL14DL4_03247 BL14DL4_03247 3100664 3101089 - hypothetical protein gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03247 BL14DL4_03248 BL14DL4_03248 BL14DL4_03248 3101184 3102131 + putative HTH-type transcriptional regulator YobV Contains 1 HTH deoR-type DNA-binding domain gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03248 BL14DL4_03249 BL14DL4_03249 BL14DL4_03249 3102409 3103086 + hypothetical protein gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03249 BL14DL4_03250 BL14DL4_03250 BL14DL4_03250 3103158 3104537 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaC Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in peptidoglycan%2C a modification that confers resistance to lysosyme. Is not able to deacetylate N- acetylglucosamine (GlcNAc) residues in peptidoglycan%2C but can deacylate chitin oligomers such as GlcNAc4 and GlcNAc5. Is essentially not active toward chitosan (partially deacetylated GlcNAc polymer) and has very low activity toward chitin (GlcNAc polymer). Does not deacetylate GlcNAc%3B Belongs to the polysaccharide deacetylase family%3B KEGG: baci:B1NLA3E_02370 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03250 BL14DL4_03251 BL14DL4_03251 amyA amyA 3104666 3106204 + Alpha-amylase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL00499 alpha-amylase gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03251 BL14DL4_03252 BL14DL4_03252 BL14DL4_03252 3106367 3107317 + putative HTH-type transcriptional regulator YvdE Contains 1 HTH lacI-type DNA-binding domain gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03252 BL14DL4_03253 BL14DL4_03253 BL14DL4_03253 3107436 3109196 + Glucan 1%2C4-alpha-maltohydrolase Hydrolyzes beta-cyclodextrin to maltose and glucose%2C soluble starch to maltose and glucose%2C and pullulan to panose with trace amounts of maltose and glucose. It is also able to hydrolyze acarbose. Can also exhibit a transglycosylation activity transferring glucose or maltose to another moiety of sugars by forming alpha-(1%2C6)- and alpha-(1%2C3)-glycosidic linkages upon the hydrolysis of substrate at concentrations of 5%25 or higher%3B Belongs to the glycosyl hydrolase 13 family. BbmA subfamily%3B KEGG: bld:BLi00658 null gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03253 BL14DL4_03254 BL14DL4_03254 BL14DL4_03254 3109291 3110544 + Maltodextrin-binding protein MdxE Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity%2C but is not involved in its uptake%3B Belongs to the bacterial solute-binding protein 1 family gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03254 BL14DL4_03255 BL14DL4_03255 BL14DL4_03255 3110586 3111893 + Maltodextrin transport system permease protein MalC Part of the binding-protein-dependent transport system for maltodextri%3B probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03255 BL14DL4_03256 BL14DL4_03256 BL14DL4_03256 3111894 3112745 + Maltodextrin transport system permease protein MdxG Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03256 BL14DL4_03257 BL14DL4_03257 BL14DL4_03257 3112750 3113631 + Putative maltodextrin utilization protein YvdJ gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03257 BL14DL4_03258 BL14DL4_03258 mapA mapA 3113609 3115891 + Maltose phosphorylase Catalyzes the phosphorolysis of maltose%2C leading to the formation of glucose and glucose 1-P%3B Belongs to the glycosyl hydrolase 65 family%3B KEGG: bsu:BSU34570 maltose phosphorylase gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03258 BL14DL4_03259 BL14DL4_03259 BL14DL4_03259 3115888 3117594 + Alpha-glucosidase Hydrolyzes various disaccharides such as sucrose%2C maltose%2C and isomaltose with different efficiencies. Also hydrolyzes longer maltodextrins from maltotriose up to maltohexaose%2C but not maltoheptaose%2C palatinose%2C isomaltotriose%2C or isomaltotetraose. Belongs to the glycosyl hydrolase 13 family%3B KEGG: rah:Rahaq_2679 alpha-glucosidase gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03259 BL14DL4_03260 BL14DL4_03260 BL14DL4_03260 3117591 3118271 + Beta-phosphoglucomutase Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P)%2C and forming beta-D-glucose 1%2C6-(bis)phosphate (beta-G16P) as an intermediate. The beta- phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose (By similarity)%3B Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03260 BL14DL4_03261 BL14DL4_03261 BL14DL4_03261 3118554 3119807 - Tyrosine--tRNA ligase Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL00484 tyrosyl-tRNA synthetase gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03261 BL14DL4_03262 BL14DL4_03262 BL14DL4_03262 3120063 3120569 - putative HTH-type transcriptional regulator YwaE Contains 1 HTH marR-type DNA-binding domain gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03262 BL14DL4_03263 BL14DL4_03263 BL14DL4_03263 3120706 3121272 - hypothetical protein gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03263 BL14DL4_03264 BL14DL4_03264 BL14DL4_03264 3121269 3121661 - hypothetical protein gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03264 BL14DL4_03265 BL14DL4_03265 BL14DL4_03265 3121863 3122243 + uncharacterized protein gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03265 BL14DL4_03266 BL14DL4_03266 BL14DL4_03266 3122300 3123319 + uncharacterized protein gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03266 BL14DL4_03267 BL14DL4_03267 BL14DL4_03267 3123362 3124354 - uncharacterized protein gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03267 BL14DL4_03268 BL14DL4_03268 BL14DL4_03268 3124447 3124749 - hypothetical protein gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03268 BL14DL4_03269 BL14DL4_03269 BL14DL4_03269 3124881 3125138 - hypothetical protein gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03269 BL14DL4_03270 BL14DL4_03270 lepB lepB 3125426 3125974 + Signal peptidase I Essential for cell viability%3B Belongs to the peptidase S26 family%3B KEGG: bli:BL00487 signal peptidase I gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03270 BL14DL4_03271 BL14DL4_03271 BL14DL4_03271 3126426 3126710 + hypothetical protein gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03271 BL14DL4_03272 BL14DL4_03272 codA codA 3127029 3127673 + Cytosine deaminase Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: sfa:Sfla_2548 cytosine deaminase gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03272 BL14DL4_03273 BL14DL4_03273 BL14DL4_03273 3127716 3128588 - Lactose operon transcription activator Transcriptional regulator of the lacPH genes for lactose utilization. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03273 BL14DL4_03274 BL14DL4_03274 BL14DL4_03274 3128697 3130238 - Spore coat protein Involved in brown pigmentation during sporogenesis. To S. antibioticus phenoxazinone synthase (PhsA) gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03274 BL14DL4_03275 BL14DL4_03275 BL14DL4_03275 3130510 3131520 + hypothetical protein gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03275 BL14DL4_03276 BL14DL4_03276 BL14DL4_03276 3131558 3132055 - hypothetical protein gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03276 BL14DL4_03277 BL14DL4_03277 BL14DL4_03277 3132702 3133574 + putative transporter YeaB Belongs to the cation diffusion facilitator (CDF) transporter (TC 2. A. 4) family gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03277 BL14DL4_03278 BL14DL4_03278 BL14DL4_03278 3133734 3134696 + uncharacterized protein Belongs to the MoxR family%3B KEGG: bsu:BSU06330 MoxR-like ATPase%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03278 BL14DL4_03279 BL14DL4_03279 BL14DL4_03279 3134696 3135907 + uncharacterized protein gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03279 BL14DL4_03280 BL14DL4_03280 BL14DL4_03280 3135912 3138137 + uncharacterized protein gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03280 BL14DL4_03281 BL14DL4_03281 guaA guaA 3138326 3139867 + GMP synthase (glutamine-hydrolyzing) Catalyzes the synthesis of GMP from XMP%3B Contains 1 glutamine amidotransferase type-1 domain%3B Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain%3B KEGG: bsu:BSU06360 GMP synthase (glutamine-hydrolysing) gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03281 BL14DL4_03282 BL14DL4_03282 BL14DL4_03282 3140491 3141813 + Putative permease Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2. A. 1. 40) subfamily gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03282 BL14DL4_03283 BL14DL4_03283 BL14DL4_03283 3142030 3142788 + uncharacterized protein gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03283 BL14DL4_03284 BL14DL4_03284 BL14DL4_03284 3142910 3143098 + hypothetical protein gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03284 BL14DL4_03285 BL14DL4_03285 BL14DL4_03285 3143284 3143838 + UPF0316 protein Belongs to the UPF0316 family gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03285 BL14DL4_03286 BL14DL4_03286 BL14DL4_03286 3143838 3144035 + uncharacterized protein gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03286 BL14DL4_03287 BL14DL4_03287 purE purE 3144353 3144841 + 5-(carboxyamino)imidazole ribonucleotide mutase In the C-terminal sectio%3B belongs to the AIR carboxylase family. Class I subfamily%3B Contains 1 ATP-grasp domain%3B KEGG: sml:Smlt1613 5-(carboxyamino)imidazole ribonucleotide mutase gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03287 BL14DL4_03288 BL14DL4_03288 purK purK 3144825 3145976 + 5-(carboxyamino)imidazole ribonucleotide synthase Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)%3B Belongs to the PurK/PurT family%3B Contains 1 ATP-grasp domain%3B KEGG: bld:BLi00694 5-(carboxyamino)imidazole ribonucleotide synthase gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03288 BL14DL4_03289 BL14DL4_03289 purB purB 3145973 3147268 + Adenylosuccinate lyase Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability. Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily%3B KEGG: afe:Lferr_1990 adenylosuccinate lyase gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03289 BL14DL4_03290 BL14DL4_03290 purC purC 3147343 3148059 + Phosphoribosylaminoimidazolesuccinocarboxamide synthase Belongs to the SAICAR synthetase family%3B KEGG: bsu:BSU06450 phosphoribosylaminoimidazole-succinocarboxamide synthase gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03290 BL14DL4_03291 BL14DL4_03291 purL purL 3148061 3148315 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the PurS family%3B KEGG: bsu:BSU06460 phosphoribosylformylglycinamidine synthase gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03291 BL14DL4_03292 BL14DL4_03292 BL14DL4_03292 3148312 3148995 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU06470 phosphoribosylformylglycinamidine synthase gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03292 BL14DL4_03293 BL14DL4_03293 BL14DL4_03293 3148979 3151207 + Phosphoribosylformylglycinamidine synthase Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL%3B Belongs to the FGAMS family%3B KEGG: bsu:BSU06480 phosphoribosylformylglycinamidine synthase gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03293 BL14DL4_03294 BL14DL4_03294 purF purF 3151183 3152613 + Amidophosphoribosyltransferase Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine%3B In the C-terminal sectio%3B belongs to the purine/pyrimidine phosphoribosyltransferase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: bsu:BSU06490 amidophosphoribosyltransferase gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03294 BL14DL4_03295 BL14DL4_03295 purM purM 3152734 3153777 + Phosphoribosylformylglycinamidine cyclo-ligase Belongs to the AIR synthase family%3B KEGG: bld:BLi00701 phosphoribosylformylglycinamidine cyclo-ligase gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03295 BL14DL4_03296 BL14DL4_03296 purN purN 3153774 3154361 + Phosphoribosylglycinamide formyltransferase Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR)%2C producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate%3B Belongs to the GART family%3B KEGG: bsu:BSU06510 phosphoribosylglycinamide formyltransferase 1 gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03296 BL14DL4_03297 BL14DL4_03297 purH purH 3154358 3155896 + Phosphoribosylaminoimidazolecarboxamide formyltransferase Belongs to the PurH family%3B KEGG: bpn:BPEN_575 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03297 BL14DL4_03298 BL14DL4_03298 purD purD 3155910 3157178 + Phosphoribosylamine--glycine ligase Belongs to the GARS family%3B Contains 1 ATP-grasp domain%3B KEGG: pbr:PB2503_12869 phosphoribosylamine--glycine ligase gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03298 BL14DL4_03299 BL14DL4_03299 BL14DL4_03299 3157498 3157806 - hypothetical protein gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03299 BL14DL4_03300 BL14DL4_03300 BL14DL4_03300 3157945 3159168 + Putative cytochrome P450 YjiB Belongs to the cytochrome P450 family%3B KEGG: bay:RBAM_012290 null%3B Acting on paired donors%2C with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O(2) gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03300 BL14DL4_03301 BL14DL4_03301 BL14DL4_03301 3159742 3159852 + hypothetical protein gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03301 BL14DL4_03302 BL14DL4_03302 BL14DL4_03302 3159864 3160310 + putative lipoprotein YybP gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03302 BL14DL4_03303 BL14DL4_03303 BL14DL4_03303 3160413 3160829 + hypothetical protein gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03303 BL14DL4_03304 BL14DL4_03304 BL14DL4_03304 3160908 3161138 - putative membrane protein YezF gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03304 BL14DL4_03305 BL14DL4_03305 BL14DL4_03305 3161264 3163003 + Adenine deaminase Belongs to the adenine deaminase family%3B KEGG: bli:BL01492 adenine deaminase gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03305 BL14DL4_03306 BL14DL4_03306 BL14DL4_03306 3163029 3164018 + Putative lipoprotein YerB gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03306 BL14DL4_03307 BL14DL4_03307 BL14DL4_03307 3164021 3164332 + uncharacterized protein gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03307 BL14DL4_03308 BL14DL4_03308 pcrB pcrB 3164483 3165169 + Heptaprenylglyceryl phosphate synthase Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepP%3B 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P)%2C producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales%3B Belongs to the GGGP/HepGP synthase family%3B KEGG: bsu:BSU06600 putative glycerol-1-phosphate prenyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03308 BL14DL4_03309 BL14DL4_03309 BL14DL4_03309 3165229 3167448 + DNA helicase DNA helicase used for plasmid rolling-circle replication and also involved in UV repair. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsu:BSU06610 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03309 BL14DL4_03310 BL14DL4_03310 ligA ligA 3167482 3169485 + DNA ligase (NAD(+)) DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA%3B Belongs to the NAD-dependent DNA ligase family. LigA subfamily%3B Contains 1 BRCT domain%3B KEGG: bli:BL00589 DNA ligase (NAD+) gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03310 BL14DL4_03311 BL14DL4_03311 BL14DL4_03311 3169501 3170691 + putative lipoprotein YerH gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03311 BL14DL4_03312 BL14DL4_03312 BL14DL4_03312 3170880 3171806 + uncharacterized protein gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03312 BL14DL4_03313 BL14DL4_03313 BL14DL4_03313 3171907 3172272 + hypothetical protein gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03313 BL14DL4_03314 BL14DL4_03314 BL14DL4_03314 3172285 3172644 + uncharacterized protein gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03314 BL14DL4_03315 BL14DL4_03315 BL14DL4_03315 3172789 3174090 + uncharacterized protein gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03315 BL14DL4_03316 BL14DL4_03316 BL14DL4_03316 3174117 3175001 + Aryldialkylphosphatase Has a low paraoxonase activity. Also active%2C but with a lower activity%2C against other organo-phosphorus insecticides such as Dursban%2C Coumaphos%2C pNP-butanoate or parathion%3B Belongs to the phosphotriesterase family gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03316 BL14DL4_03317 BL14DL4_03317 BL14DL4_03317 3174998 3176146 + Cysteine desulfurase KEGG: frf:LO80_09340 cysteine desulfurase / selenocysteine lyase gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03317 BL14DL4_03318 BL14DL4_03318 BL14DL4_03318 3176139 3177365 + Phosphopentomutase Belongs to the phosphopentomutase family%3B KEGG: aac:Aaci_1749 phosphopentomutase gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03318 BL14DL4_03319 BL14DL4_03319 BL14DL4_03319 3177365 3178516 + uncharacterized protein gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03319 BL14DL4_03320 BL14DL4_03320 BL14DL4_03320 3178656 3179384 + Glucosamine-6-phosphate deaminase Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion%3B Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily%3B KEGG: bli:BL00599 glucosamine-6-phosphate deaminase gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03320 BL14DL4_03321 BL14DL4_03321 BL14DL4_03321 3179700 3180392 - Protein SapB Belongs to the MgtC/SapB family gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03321 BL14DL4_03322 BL14DL4_03322 BL14DL4_03322 3180616 3182097 - Osmoregulated proline transporter OpuE Catalyzes the uptake of extracellular proline under high-osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant%3B Belongs to the sodium:solute symporter (SSF) (TC 2. A. 21) family gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03322 BL14DL4_03323 BL14DL4_03323 BL14DL4_03323 3182318 3182479 + hypothetical protein gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03323 BL14DL4_03324 BL14DL4_03324 gatC gatC 3182539 3182829 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)%3B Belongs to the GatC family%3B KEGG: mmn:midi_00552 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03324 BL14DL4_03325 BL14DL4_03325 gatA gatA 3182851 3184308 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)%3B Belongs to the amidase family. GatA subfamily%3B KEGG: bsu:BSU06680 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03325 BL14DL4_03326 BL14DL4_03326 gatB gatB 3184322 3185752 + Asparaginyl-tRNA synthase (glutamine-hydrolyzing) Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)%3B Belongs to the GatB/GatE family. GatB subfamily%3B KEGG: pae:PA4484 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03326 BL14DL4_03327 BL14DL4_03327 BL14DL4_03327 3185936 3186238 + hypothetical protein gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03327 BL14DL4_03328 BL14DL4_03328 BL14DL4_03328 3186235 3186516 + hypothetical protein gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03328 BL14DL4_03329 BL14DL4_03329 gmuG gmuG 3186591 3187586 - Mannan endo-1%2C4-beta-mannosidase Involved in the degradation of glucomannan. Catalyzes the endo hydrolysis of beta-1%2C4-linked mannan%2C galactomannan and glucomannan%3B Belongs to the glycosyl hydrolase 26 family%3B Contains 1 GH26 (glycosyl hydrolase family 26) domain%3B KEGG: bli:BL05063 mannan endo-1%2C4-beta-mannosidase gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03329 BL14DL4_03330 BL14DL4_03330 BL14DL4_03330 3187797 3188645 - putative HTH-type transcriptional regulator YerO Contains 1 HTH tetR-type DNA-binding domain gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03330 BL14DL4_03331 BL14DL4_03331 BL14DL4_03331 3188790 3191948 + Swarming motility protein SwrC Required for self-resistance to surfactin%2C an antimicrobial lipopeptide surfactant produced by B. subtilis. Also required for swarming motility%3B Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03331 BL14DL4_03332 BL14DL4_03332 BL14DL4_03332 3192095 3192295 + hypothetical protein gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03332 BL14DL4_03333 BL14DL4_03333 BL14DL4_03333 3192385 3192927 - Ribosomal-protein-alanine N-acetyltransferase This enzyme acetylates the N-terminal alanine of ribosomal protein S5%3B Belongs to the acetyltransferase family. RimJ subfamily%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL02628 ribosomal-protein-alanine N-acetyltransferase gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03333 BL14DL4_03334 BL14DL4_03334 iunH iunH 3192941 3193894 - Purine nucleosidase KEGG: bli:BL02627 purine nucleosidase gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03334 BL14DL4_03335 BL14DL4_03335 BL14DL4_03335 3194094 3195008 + Diacylglycerol kinase (ATP) Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. Is more active toward long-chain DAG compared with short-chain DAG. Is not able to phosphorylate substrates other than DAG%2C such as monoacylglycerol%2C ceramide%2C undecaprenol%2C phosphatidylinositol%2C or sphingosine%3B Belongs to the diacylglycerol/lipid kinase family%3B Contains 1 DAGKc domain%3B KEGG: bsu:BSU06720 diacylglycerol kinase (ATP) gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03335 BL14DL4_03336 BL14DL4_03336 rumA rumA 3195057 3196433 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: bli:BL02629 23S rRNA (uracil1939-C5)-methyltransferase gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03336 BL14DL4_03337 BL14DL4_03337 BL14DL4_03337 3196677 3198245 + hypothetical protein gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03337 BL14DL4_03338 BL14DL4_03338 BL14DL4_03338 3198328 3199506 + DNA (cytosine-5-)-methyltransferase This methylase recognizes the double-stranded sequence GCWGC%2C causes specific methylation on C-2 on both strands%2C and protects the DNA from cleavage by the BbvI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family%3B Contains 1 SAM-dependent MTase C5-type domain%3B KEGG: tco:Theco_3624 DNA (cytosine-5)-methyltransferase 1 gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03338 BL14DL4_03339 BL14DL4_03339 BL14DL4_03339 3199543 3199965 - Putative NmeDIP very short patch repair endonuclease May nick NmeDIP sequences that contain T:G mispairs resulting from m5C-deamination%3B Belongs to the vsr family%3B KEGG: gyc:GYMC61_3575 DNA mismatch endonuclease%2C patch repair protein%3B Acting on ester bonds gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03339 BL14DL4_03340 BL14DL4_03340 BL14DL4_03340 3200521 3202386 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in beta-glucoside transport (By similarity)%3B Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL02334 PTS system%2C beta-glucosides-specific IIA component gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03340 BL14DL4_03341 BL14DL4_03341 BL14DL4_03341 3202389 3203858 + 6-phospho-beta-glucosidase Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P)%2C phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells%3B Belongs to the glycosyl hydrolase 1 family%3B KEGG: bld:BLi00749 6-phospho-beta-glucosidase gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03341 BL14DL4_03342 BL14DL4_03342 BL14DL4_03342 3203888 3204736 + PtsGHI operon antiterminator Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence%3B Belongs to the transcriptional antiterminator BglG family. GlcT subfamily%3B Contains 2 PRD domains gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03342 BL14DL4_03343 BL14DL4_03343 BL14DL4_03343 3204984 3206096 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bsu:BSU18910 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03343 BL14DL4_03344 BL14DL4_03344 BL14DL4_03344 3206093 3206215 + hypothetical protein gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03344 BL14DL4_03345 BL14DL4_03345 BL14DL4_03345 3206381 3207139 + hypothetical protein gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03345 BL14DL4_03346 BL14DL4_03346 BL14DL4_03346 3207551 3208270 + putative transcriptional regulatory protein Belongs to the TACO1 family gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03346 BL14DL4_03347 BL14DL4_03347 BL14DL4_03347 3208427 3208636 + putative HTH-type transcriptional regulator Contains 1 HTH cro/C1-type DNA-binding domain gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03347 BL14DL4_03348 BL14DL4_03348 BL14DL4_03348 3208629 3208943 + hypothetical protein gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03348 BL14DL4_03349 BL14DL4_03349 BL14DL4_03349 3209101 3210558 + Aldehyde dehydrogenase (NAD(+)) Belongs to the aldehyde dehydrogenase family%3B KEGG: bli:BL02341 aldehyde dehydrogenase (NAD+) gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03349 BL14DL4_03350 BL14DL4_03350 BL14DL4_03350 3210575 3211426 + Putative sensory transducer protein YfmS Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity)%3B Contains 1 methyl-accepting transducer domain gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03350 BL14DL4_03351 BL14DL4_03351 BL14DL4_03351 3211572 3212996 + Sodium-dependent dicarboxylate transporter SdcS Mediates the transport of the dicarboxylates fumarate%2C malate%2C and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient%3B Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. NADC subfamily gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03351 BL14DL4_03352 BL14DL4_03352 BL14DL4_03352 3213081 3214970 + putative ABC transporter ATP-binding protein YfmR Belongs to the ABC transporter superfamily%3B Contains 2 ABC transporter domains gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03352 BL14DL4_03353 BL14DL4_03353 gch4 gch4 3215139 3216041 - GTP cyclohydrolase I Converts GTP to 7%2C8-dihydroneopterin triphosphate%3B Belongs to the GTP cyclohydrolase IV family%3B KEGG: bli:BL02349 GTP cyclohydrolase I gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03353 BL14DL4_03354 BL14DL4_03354 BL14DL4_03354 3216174 3217286 + Baeyer-Villiger flavin-containing monooxygenase Catalyzes a Baeyer-Villiger oxidation reaction%2C i. e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl%2C which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03354 BL14DL4_03355 BL14DL4_03355 BL14DL4_03355 3217310 3218953 + Ferrous iron transport protein B like protein It seems that the Fe(2+) uptake in C. jejuni cannot be attributed to FeoB%3B Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. FeoB GTPase (TC 9. A. 8) family%3B Contains 1 FeoB-type G (guanine nucleotide-binding) domain gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03355 BL14DL4_03356 BL14DL4_03356 BL14DL4_03356 3219019 3220221 + Putative metal chaperone YciC May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03356 BL14DL4_03357 BL14DL4_03357 bioW bioW 3220390 3221175 + 6-carboxyhexanoate--CoA ligase Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP%3B Belongs to the BioW family%3B KEGG: bli:BL02411 6-carboxyhexanoate--CoA ligase gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03357 BL14DL4_03358 BL14DL4_03358 BL14DL4_03358 3221156 3222502 + Lysine--8-amino-7-oxononanoate transaminase Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7%2C8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor%3B Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily%3B KEGG: bli:BL00953 lysine---8-amino-7-oxononanoate aminotransferase gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03358 BL14DL4_03359 BL14DL4_03359 bioF bioF 3222492 3223631 + 8-amino-7-oxononanoate synthase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bli:BL00954 8-amino-7-oxononanoate synthase gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03359 BL14DL4_03360 BL14DL4_03360 bioD bioD 3223628 3224335 + Dethiobiotin synthase Catalyzes a mechanistically unusual reaction%2C the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7%2C8-diaminopelargonic acid (DAPA) to form an ureido ring%3B Belongs to the dethiobiotin synthetase family%3B KEGG: acu:Atc_2625 dethiobiotin synthetase gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03360 BL14DL4_03361 BL14DL4_03361 bioB bioB 3224332 3225333 + Biotin synthase Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism%3B Belongs to the radical SAM superfamily. Biotin synthase family%3B KEGG: bsu:BSU30200 biotin synthase gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03361 BL14DL4_03362 BL14DL4_03362 bioI bioI 3225351 3226547 + Pimeloyl-[acyl-carrier protein] synthase Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid%3B Belongs to the cytochrome P450 family%3B KEGG: bli:BL00957 pimeloyl-(acyl-carrier protein) synthase gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03362 BL14DL4_03363 BL14DL4_03363 BL14DL4_03363 3226590 3227420 - Sodium channel protein 1 brain Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane%2C the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Belongs to the sodium channel (TC 1. A. 1. 10) family gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03363 BL14DL4_03364 BL14DL4_03364 BL14DL4_03364 3227584 3228006 + HTH-type transcriptional regulator YfmP Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO%2C probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA%3B Contains 1 HTH merR-type DNA-binding domain gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03364 BL14DL4_03365 BL14DL4_03365 BL14DL4_03365 3228065 3229249 + Multidrug efflux protein YfmO Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance%3B Belongs to the major facilitator superfamily gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03365 BL14DL4_03366 BL14DL4_03366 BL14DL4_03366 3229292 3230848 - Heme-transporting ATPase Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain%3B KEGG: etr:ETAE_2461 heme exporter protein A gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03366 BL14DL4_03367 BL14DL4_03367 BL14DL4_03367 3230986 3232116 + RNA helicase A probable DEAD-box RNA helicase that plays a role in ribosomal 50S subunit assembly. May be a non-specific RNA helicase%3B Belongs to the DEAD box helicase family%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: ssu:SSU05_1739 ATP-dependent RNA helicase CshB gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03367 BL14DL4_03368 BL14DL4_03368 BL14DL4_03368 3232160 3233182 - Putative NADP-dependent oxidoreductase YfmJ Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds%3B Belongs to the NADP-dependent oxidoreductase L4BD family gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03368 BL14DL4_03369 BL14DL4_03369 BL14DL4_03369 3233239 3233622 - uncharacterized protein gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03369 BL14DL4_03370 BL14DL4_03370 BL14DL4_03370 3233817 3234164 + General stress protein 17M gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03370 BL14DL4_03371 BL14DL4_03371 BL14DL4_03371 3234274 3235710 + Putative malate transporter YflS Might be a malate transporter. Belongs to the SLC13A/DASS transporter (TC 2. A. 47) family. DIT1 subfamily gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03371 BL14DL4_03372 BL14DL4_03372 BL14DL4_03372 3235838 3236415 + Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03372 BL14DL4_03373 BL14DL4_03373 BL14DL4_03373 3236462 3237244 - Hydroxyacylglutathione hydrolase Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family%3B KEGG: rha:RHA1_ro06806 hydroxyacylglutathione hydrolase gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03373 BL14DL4_03374 BL14DL4_03374 BL14DL4_03374 3237347 3238144 + putative metallo-hydrolase YflN Belongs to the metallo-beta-lactamase superfamily gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03374 BL14DL4_03375 BL14DL4_03375 BL14DL4_03375 3238353 3239996 + putative carboxypeptidase Extracellular metalloprotease that contributes to pathogenicity%3B Belongs to the peptidase M14 family gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03375 BL14DL4_03376 BL14DL4_03376 BL14DL4_03376 3240125 3241222 + Nitric-oxide synthase (NAD(P)H) Catalyzes the production of nitric oxide%3B Belongs to the NOS family. Bacterial NOS oxygenase subfamily%3B KEGG: bli:BL03064 nitric-oxide synthase%2C bacterial gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03376 BL14DL4_03377 BL14DL4_03377 BL14DL4_03377 3241310 3241948 - hypothetical protein gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03377 BL14DL4_03378 BL14DL4_03378 BL14DL4_03378 3241945 3242229 - HTH-type transcriptional regulator KmtR Represses expression of Rv2025c and its own expression. Acts by binding to the promoter regions%3B Contains 1 HTH arsR-type DNA-binding domain gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03378 BL14DL4_03379 BL14DL4_03379 acyP acyP 3242336 3242608 - Acylphosphatase Belongs to the acylphosphatase family%3B Contains 1 acylphosphatase-like domain%3B KEGG: bsu:BSU07640 acylphosphatase gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03379 BL14DL4_03380 BL14DL4_03380 BL14DL4_03380 3242720 3243370 + uncharacterized protein Contains 1 MOSC domain gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03380 BL14DL4_03381 BL14DL4_03381 BL14DL4_03381 3243597 3243728 - uncharacterized protein gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03381 BL14DL4_03382 BL14DL4_03382 BL14DL4_03382 3243860 3244015 - uncharacterized protein gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03382 BL14DL4_03383 BL14DL4_03383 BL14DL4_03383 3244101 3244853 - Methionyl aminopeptidase Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-%2C Cys%2C Gly%2C Pro%2C Ser%2C Thr%2C or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed%3B Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily%3B KEGG: ara:Arad_3299 methionyl aminopeptidase gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03383 BL14DL4_03384 BL14DL4_03384 BL14DL4_03384 3244978 3246939 - Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate%2C a reaction that presumably uses phosphatidylglycerol (PG) as substrate%3B Belongs to the LTA synthase family%3B KEGG: bld:BLi00793 lipoteichoic acid synthase gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03384 BL14DL4_03385 BL14DL4_03385 BL14DL4_03385 3247201 3247587 + uncharacterized protein gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03385 BL14DL4_03386 BL14DL4_03386 BL14DL4_03386 3247649 3249061 + putative transporter YflA Belongs to the sodium:alanine (SAF) symporter family gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03386 BL14DL4_03387 BL14DL4_03387 treB treB 3249251 3250663 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in trehalose transport. Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bsu:BSU07800 PTS system%2C trehalose-specific IIB component gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03387 BL14DL4_03388 BL14DL4_03388 treC treC 3250737 3252425 + Alpha%2Calpha-phosphotrehalase Belongs to the glycosyl hydrolase 13 family%3B KEGG: bli:BL03069 trehalose-6-phosphate hydrolase gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03388 BL14DL4_03389 BL14DL4_03389 BL14DL4_03389 3252447 3253163 + Trehalose operon transcriptional repressor Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate%2C which probably acts as an inducer. Contains 1 HTH gntR-type DNA-binding domain gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03389 BL14DL4_03390 BL14DL4_03390 lpxA lpxA 3253270 3253962 + Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Involved in the biosynthesis of lipid A%2C a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell%3B Belongs to the transferase hexapeptide repeat family. LpxA subfamily%3B KEGG: mvs:MVIS_3839 UDP-N-acetylglucosamine acyltransferase gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03390 BL14DL4_03391 BL14DL4_03391 BL14DL4_03391 3254089 3255423 + Mucin-5AC Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Contains 1 CTCK (C-terminal cystine knot-like) domain%3B Contains 3 TIL (trypsin inhibitory-like) domains%3B Contains 4 VWFC domains%3B Contains 4 VWFD domains gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03391 BL14DL4_03392 BL14DL4_03392 BL14DL4_03392 3256104 3258524 - Pulmonary surfactant-associated protein Contributes to the lung's defense against inhaled microorganisms%2C organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides%2C oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties (By similarity)%3B Belongs to the SFTPD family%3B Contains 1 C-type lectin domain%3B Contains 1 collagen-like domain gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03392 BL14DL4_03393 BL14DL4_03393 BL14DL4_03393 3259149 3261434 + Glycine-rich cell wall structural protein 1.0 Responsible for plasticity of the cell wall gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03393 BL14DL4_03394 BL14DL4_03394 arnB arnB 3261612 3262703 - UDP-4-amino-4-deoxy-L-arabinose aminotransferase Catalyzes the synthesis of GDP-perosamine from GDP-4- keto-6-deoxy-D-mannose and L-glutamate. Can use only L-glutamate as amino donor%3B Belongs to the DegT/DnrJ/EryC1 family%3B KEGG: pam:PANA_4002 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03394 BL14DL4_03395 BL14DL4_03395 BL14DL4_03395 3262700 3263242 - Maltose O-acetyltransferase Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: vni:VIBNI_B1816 maltose O-acetyltransferase gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03395 BL14DL4_03396 BL14DL4_03396 BL14DL4_03396 3263260 3264234 - UDP-glucose 4-epimerase Trifunctional enzyme involved in UDP-beta-L-rhamnose biosynthesis%2C a precursor of the primary cell wall components rhamnogalacturonan I (RG-I) and rhamnogalacturonan II (RG-II) (PubMed:14671019%2C PubMed:17190829%2C PubMed:19056285). Plays a major role in supplying UDP-rhamnose for flavonol biosynthesis (PubMed:18757557). Catalyzes the dehydration of UDP-glucose to form UDP-4-dehydro-6-deoxy-D-glucose followed by the epimerization of the C3' and C5' positions of UDP-4-dehydro-6-deoxy-D-glucose to form UDP-4-keto-beta-L-rhamnose and the reduction of UDP-4-keto- beta-L-rhamnose to yield UDP-beta-L-rhamnose (By similarity)%3B In the N-terminal sectio%3B belongs to the NAD(P)- dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily%3B In the C-terminal sectio%3B belongs to the dTDP-4- dehydrorhamnose reductase family%3B KEGG: blh:BaLi_c09080 UDP-glucose 4-epimerase gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03396 BL14DL4_03397 BL14DL4_03397 BL14DL4_03397 3264301 3265674 - hypothetical protein gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03397 BL14DL4_03398 BL14DL4_03398 migA migA 3265829 3268072 - putative glycosyltransferase Belongs to the glycosyltransferase 2 family%3B KEGG: pen:PSEEN4078 alpha-1%2C6-rhamnosyltransferase%3B Hexosyltransferases gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03398 BL14DL4_03399 BL14DL4_03399 BL14DL4_03399 3268267 3269349 + TPR repeat-containing protein Contains 5 TPR repeats%3B KEGG: bcz:BCZK1105 null%3B Hexosyltransferases gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03399 BL14DL4_03400 BL14DL4_03400 BL14DL4_03400 3269388 3270581 + dTDP-3-amino-3%2C4%2C6-trideoxy-alpha-D-glucose transaminase Involved in the biosynthesis of dTDP-alpha-D-desosamine%2C a sugar found in several bacterial macrolide antibiotics. Catalyzes the reversible transfer of the amino group from L- glutamate to the C-3 position of dTDP-3-keto-4%2C6-deoxyglucose to yield dTDP-3-amino-3%2C4%2C6-trideoxyglucose%3B Belongs to the degT/dnrJ/eryC1 family%3B KEGG: csc:Csac_1802 null%3B Transaminases gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03400 BL14DL4_03401 BL14DL4_03401 wlbA wlbA 3270578 3271642 + UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: plu:plu4797 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03401 BL14DL4_03402 BL14DL4_03402 wbpA wbpA 3271728 3273023 + UDP-N-acetylglucosamine 6-dehydrogenase Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc)%2C reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA)%3B Belongs to the UDP-glucose/GDP-mannose dehydrogenase family%3B KEGG: blh:BaLi_c09140 UDP-N-acetyl-D-glucosamine dehydrogenase gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03402 BL14DL4_03403 BL14DL4_03403 BL14DL4_03403 3273104 3274015 + uncharacterized protein gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03403 BL14DL4_03404 BL14DL4_03404 BL14DL4_03404 3274012 3274404 - putative HTH-type transcriptional regulator YtcD Contains 1 HTH hxlR-type DNA-binding domain gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03404 BL14DL4_03405 BL14DL4_03405 BL14DL4_03405 3274535 3275218 + Putative NAD(P)H nitroreductase YfkO Belongs to the nitroreductase family%3B KEGG: oih:OB3126 null%3B Oxidoreductases gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03405 BL14DL4_03406 BL14DL4_03406 yfkN yfkN 3275260 3279594 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase Catalyzes the release of inorganic phosphate from 2'%2C3'- cyclic nucleotides through consecutive 2'%2C3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3'%2C5'-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium%2C under conditions of phosphate shortage%3B Belongs to the 5'-nucleotidase family%3B KEGG: bli:BL03110 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03406 BL14DL4_03407 BL14DL4_03407 BL14DL4_03407 3279826 3280341 + General stress protein Functions in the protection against aldehyde-stress%2C possibly by degrading damaged proteins%3B Belongs to the peptidase C56 family%3B Contains 1 PfpI endopeptidase domain%3B KEGG: eco:b3153 protease I%3B Glycosylases gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03407 BL14DL4_03408 BL14DL4_03408 BL14DL4_03408 3280382 3280597 - UPF0435 protein Belongs to the UPF0435 family gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03408 BL14DL4_03409 BL14DL4_03409 BL14DL4_03409 3280687 3282045 - Sodium/alanine symporter AgcS Probably functions as a sodium/L- and D-alanine symporter for alanine uptake%3B Belongs to the sodium:alanine (SAF) symporter family gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03409 BL14DL4_03410 BL14DL4_03410 BL14DL4_03410 3282229 3282699 + Protein-tyrosine-phosphatase May contribute to dephosphorylation of 'Tyr-15' of cdc2. Belongs to the low molecular weight phosphotyrosine protein phosphatase family%3B KEGG: aat:D11S_0095 protein-tyrosine phosphatase gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03410 BL14DL4_03411 BL14DL4_03411 BL14DL4_03411 3282721 3283071 + uncharacterized protein gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03411 BL14DL4_03412 BL14DL4_03412 BL14DL4_03412 3283068 3283883 + Putative ribonuclease-like protein YfkH gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03412 BL14DL4_03413 BL14DL4_03413 BL14DL4_03413 3283932 3284039 + hypothetical protein gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03413 BL14DL4_03414 BL14DL4_03414 BL14DL4_03414 3284079 3285257 - putative MFS-type transporter YfkF Belongs to the major facilitator superfamily gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03414 BL14DL4_03415 BL14DL4_03415 BL14DL4_03415 3285358 3285738 + hypothetical protein gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03415 BL14DL4_03416 BL14DL4_03416 BL14DL4_03416 3285843 3286898 + Ca(2+)/H(+) antiporter ChaA Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium%3B Belongs to the sodium/potassium/calcium exchanger family. Cation/proton exchanger (CAX) (TC 2. A. 19. 2) subfamily gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03416 BL14DL4_03417 BL14DL4_03417 BL14DL4_03417 3286965 3287756 + uncharacterized protein gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03417 BL14DL4_03418 BL14DL4_03418 BL14DL4_03418 3287785 3288906 - Putative protein YfkA Belongs to the radical SAM superfamily gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03418 BL14DL4_03419 BL14DL4_03419 BL14DL4_03419 3289050 3289235 + uncharacterized protein gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03419 BL14DL4_03420 BL14DL4_03420 BL14DL4_03420 3289342 3290136 + Peptidoglycan-N-acetylmuramic acid deacetylase PdaA Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in glycan strands of peptidoglycan%2C leading to the formation of muramic delta-lactam residues in spore cortex%2C after transpeptidation of deacetylated muramic acid residues. PdaA probably carries out both deacetylation and lactam ring formation and requires the product of CwlD activity on peptidoglycan as a substrate. Is required for germination. Cannot use chitin oligomer (hexa-N-acetylchitohexaose) as a substrate%3B Belongs to the polysaccharide deacetylase family%3B KEGG: bld:BLi00827 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03420 BL14DL4_03421 BL14DL4_03421 gldA gldA 3290313 3291416 + Glycerol dehydrogenase Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates%2C such as propan-1%2C2-diol%2C butan-2%2C3-diol%2C ethan-1%2C2-diol%2C and 3-mercapto-1%2C2- dihydroxypropane%3B Belongs to the iron-containing alcohol dehydrogenase family%3B KEGG: bli:BL03089 glycerol dehydrogenase gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03421 BL14DL4_03422 BL14DL4_03422 BL14DL4_03422 3291601 3292197 - hypothetical protein gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03422 BL14DL4_03423 BL14DL4_03423 BL14DL4_03423 3292255 3293214 - Putative metal ion transporter YfjQ Belongs to the CorA metal ion transporter (MIT) (TC 1. A. 35) family gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03423 BL14DL4_03424 BL14DL4_03424 alkA alkA 3293348 3294211 + DNA-3-methyladenine glycosylase II Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine%2C O2- methylthymine%2C and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions%3B Belongs to the alkylbase DNA glycosidase AlkA family%3B KEGG: bli:BL03090 DNA-3-methyladenine glycosylase II gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03424 BL14DL4_03425 BL14DL4_03425 BL14DL4_03425 3294214 3295620 + 23S rRNA (uracil(1939)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family%3B Contains 1 TRAM domain%3B KEGG: blh:BaLi_c09360 23S rRNA (uracil1939-C5)-methyltransferase gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03425 BL14DL4_03426 BL14DL4_03426 BL14DL4_03426 3295670 3296149 + uncharacterized protein gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03426 BL14DL4_03427 BL14DL4_03427 BL14DL4_03427 3296716 3297279 + hypothetical protein gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03427 BL14DL4_03428 BL14DL4_03428 BL14DL4_03428 3297281 3298006 + uncharacterized protein gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03428 BL14DL4_03429 BL14DL4_03429 BL14DL4_03429 3298036 3298611 - putative HTH-type transcriptional regulator YvkB Contains 1 HTH tetR-type DNA-binding domain gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03429 BL14DL4_03430 BL14DL4_03430 BL14DL4_03430 3298719 3299915 + putative UDP-glucosyltransferase YdhE Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03430 BL14DL4_03431 BL14DL4_03431 BL14DL4_03431 3300009 3300329 + uncharacterized protein gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03431 BL14DL4_03432 BL14DL4_03432 BL14DL4_03432 3300434 3301636 + Putative niacin/nicotinamide transporter NaiP Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E. coli that is unable to make niacin de nov%3B confers increased sensitivity to the toxic niacin analog 6-amino-nicotinamide to wild-type E. coli. There is probably another mechanism for niacin uptake. Belongs to the major facilitator superfamily. Sugar transporter (TC 2. A. 1. 1) family gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03432 BL14DL4_03433 BL14DL4_03433 BL14DL4_03433 3302130 3303506 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase Negatively regulates SacY activity by catalyzing its phosphorylation on 'His-99'%3B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system may be involved in sucrose transport%3B Negatively regulates SacY%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL00914 PTS system%2C sucrose-specific IIB component gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03433 BL14DL4_03434 BL14DL4_03434 BL14DL4_03434 3303549 3304391 + Levansucrase and sucrase synthesis operon antiterminator In the presence of sucrose%2C SacY is activated and prevents premature termination of transcription by binding to a RNA-antiterminator (RAT) sequence (partially overlapping with the terminator sequence) located upstream of the sacB gene. Formation of the SacY-RAT complex prevents alternative formation of the terminator%2C allowing transcription of the sacB gene. In the absence of sucrose%2C inhibition of SacY activity by SacX leads to termination of transcription%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03434 BL14DL4_03435 BL14DL4_03435 BL14DL4_03435 3304425 3304931 - Carbonate dehydratase Belongs to the beta-class carbonic anhydrase family%3B KEGG: pjd:Pjdr2_2595 carbonic anhydrase gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03435 BL14DL4_03436 BL14DL4_03436 BL14DL4_03436 3304943 3307564 - UPF0753 protein Belongs to the UPF0753 family gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03436 BL14DL4_03437 BL14DL4_03437 ndhF ndhF 3307561 3309093 - NADH:ubiquinone reductase (H(+)-translocating) Belongs to the complex I subunit 5 family%3B KEGG: bli:BL00918 NAD(P)H-quinone oxidoreductase subunit 5 gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03437 BL14DL4_03438 BL14DL4_03438 BL14DL4_03438 3309269 3309643 - uncharacterized protein gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03438 BL14DL4_03439 BL14DL4_03439 BL14DL4_03439 3309914 3310465 - Protein DJ-1 like protein B May be involved in oxidative stress response%3B Belongs to the peptidase C56 family%3B Contains 2 PfpI endopeptidase domains gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03439 BL14DL4_03440 BL14DL4_03440 pdhA pdhA 3310675 3311649 + Pyruvate dehydrogenase (acetyl-transferring) The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B KEGG: bli:BL03012 pyruvate dehydrogenase E1 component alpha subunit gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03440 BL14DL4_03441 BL14DL4_03441 pdhB pdhB 3311671 3312705 + Pyruvate dehydrogenase (acetyl-transferring) Catalyzes the 2%2C6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde%3B KEGG: bli:BL03013 pyruvate dehydrogenase E1 component beta subunit gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03441 BL14DL4_03442 BL14DL4_03442 BL14DL4_03442 3312728 3313861 + Dihydrolipoyllysine-residue succinyltransferase The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1)%2C dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)%3B Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: hin:HI1661 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03442 BL14DL4_03443 BL14DL4_03443 pdhD pdhD 3313880 3315256 + Dihydrolipoyl dehydrogenase Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: ype:YPO3917 dihydrolipoamide dehydrogenase gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03443 BL14DL4_03444 BL14DL4_03444 BL14DL4_03444 3315359 3317194 + Acetoin dehydrogenase operon transcriptional activator AcoR Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex%3B Contains 1 sigma-54 factor interaction domain gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03444 BL14DL4_03445 BL14DL4_03445 BL14DL4_03445 3317191 3317517 - UPF0060 membrane protein Belongs to the UPF0060 family gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03445 BL14DL4_03446 BL14DL4_03446 glvA glvA 3317704 3319053 + Maltose-6'-phosphate glucosidase Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). Hydrolyzes a wide variety of 6-phospho-alpha-D- glucosides including maltose-6'-phosphate%2C isomaltose-6'- phosphate%2C maltitol-6-phosphate%2C trehalose-6-phosphate and the 6'- phosphorylated derivatives of the five linkage-isomeric alpha-D- glucosyl-D-fructoses: trehalulose-6'-phosphate%2C turanose-6'- phosphate%2C maltulose-6'-phosphate%2C leucrose-6'-phosphate%2C and palatinose-6'-phosphate. However%2C sucrose-6-phosphate is not a substrate for this enzyme%3B Belongs to the glycosyl hydrolase 4 family%3B KEGG: bli:BL03017 maltose-6'-phosphate glucosidase gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03446 BL14DL4_03447 BL14DL4_03447 BL14DL4_03447 3319153 3319932 + HTH-type transcriptional regulator GlvR Positive regulator of the glv operon expression%2C which consists of GlvA%2C GlvR and GlvC%3B Contains 1 HTH rpiR-type DNA-binding domain%3B Contains 1 SIS domain gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03447 BL14DL4_03448 BL14DL4_03448 glvB glvB 3319951 3321540 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: cro:ROD_40441 PTS system%2C arbutin-like IIB component gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03448 BL14DL4_03449 BL14DL4_03449 BL14DL4_03449 3321683 3322261 - hypothetical protein gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03449 BL14DL4_03450 BL14DL4_03450 BL14DL4_03450 3322367 3323344 - hypothetical protein gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03450 BL14DL4_03451 BL14DL4_03451 BL14DL4_03451 3323514 3323852 - putative HTH-type transcriptional regulator YvaP Contains 1 HTH hxlR-type DNA-binding domain gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03451 BL14DL4_03452 BL14DL4_03452 BL14DL4_03452 3324081 3324524 + Putative oxidoreductase CatD Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the DoxX family gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03452 BL14DL4_03453 BL14DL4_03453 BL14DL4_03453 3324496 3325356 + Catechol 2%2C3-dioxygenase Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol%3B Belongs to the extradiol ring-cleavage dioxygenase family%3B KEGG: bli:BL03021 catechol 2%2C3-dioxygenase gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03453 BL14DL4_03454 BL14DL4_03454 xynD xynD 3325512 3327116 + Non-reducing end alpha-L-arabinofuranosidase Has a 1. 6-fold higher activity as an arabinosidase than as a beta-xylosidase when tested on the substrates nitrophenyl- beta-D-xylopyranoside and P-nitrophenyl-alpha-L-arabinofuranoside. Belongs to the glycosyl hydrolase 43 family%3B KEGG: tco:Theco_2848 arabinoxylan arabinofuranohydrolase gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03454 BL14DL4_03455 BL14DL4_03455 xynB xynB 3327106 3328653 + Xylan 1%2C4-beta-xylosidase Alpha-L-arabinofuranosidase involved in xyloglucan degradation by mediating the cleavage of terminal non-reducing alpha-L-arabinofuranoside residues in xyloglucan branches%2C converting the 'S' units to 'X' units%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL03023 xylan 1%2C4-beta-xylosidase gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03455 BL14DL4_03456 BL14DL4_03456 BL14DL4_03456 3328650 3329495 - putative HTH-type transcriptional regulator YijO Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03456 BL14DL4_03457 BL14DL4_03457 BL14DL4_03457 3329546 3330949 + Putative ABC transporter peptide-binding protein YtcQ Probably part of a binding-protein-dependent transport system%3B Belongs to the bacterial solute-binding protein 1 family gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03457 BL14DL4_03458 BL14DL4_03458 BL14DL4_03458 3331146 3331739 + NAD(P)H dehydrogenase (quinone) The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis%3B Belongs to the NAD(P)H dehydrogenase (quinone) family%3B KEGG: bli:BL03025 NAD(P)H dehydrogenase (quinone) gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03458 BL14DL4_03459 BL14DL4_03459 BL14DL4_03459 3331736 3332347 + ADP-ribose diphosphatase Probably mediates the hydrolysis of some nucleoside diphosphate derivatives%3B Belongs to the Nudix hydrolase family%3B Contains 1 nudix hydrolase domain%3B KEGG: bcl:ABC0282 ADP-ribose pyrophosphatase gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03459 BL14DL4_03460 BL14DL4_03460 BL14DL4_03460 3332362 3332739 + Putative metal-dependent hydrolase Possible metal-dependent hydrolase%3B Belongs to the metal hydrolase YfiT family gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03460 BL14DL4_03461 BL14DL4_03461 mprF mprF 3333081 3335633 + Lysyltransferase Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG)%2C which produces lysylphosphatidylglycerol (LPG)%2C one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects B. subtilis against its own CAMPs and against those produced by competiting microorganisms (bacteriocins). In fact%2C the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides%3B Belongs to the LPG synthase family%3B KEGG: bli:BL03028 phosphatidylglycerol lysyltransferase gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03461 BL14DL4_03462 BL14DL4_03462 BL14DL4_03462 3335630 3335761 + hypothetical protein gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03462 BL14DL4_03463 BL14DL4_03463 BL14DL4_03463 3335748 3336644 + Trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase Belongs to the PhzF family%3B KEGG: rle:RL4013 trans-2%2C3-dihydro-3-hydroxyanthranilate isomerase gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03463 BL14DL4_03464 BL14DL4_03464 bluB bluB 3336744 3337322 + 5%2C6-dimethylbenzimidazole synthase Belongs to the nitroreductase family%3B KEGG: baci:B1NLA3E_15285 5%2C6-dimethylbenzimidazole synthase gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03464 BL14DL4_03465 BL14DL4_03465 BL14DL4_03465 3337362 3337556 - uncharacterized protein gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03465 BL14DL4_03466 BL14DL4_03466 BL14DL4_03466 3337625 3337738 - hypothetical protein gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03466 BL14DL4_03467 BL14DL4_03467 BL14DL4_03467 3337805 3338335 - Ribosomal-protein-alanine N-acetyltransferase KEGG: bce:BC4195 ribosomal-protein-alanine N-acetyltransferase gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03467 BL14DL4_03468 BL14DL4_03468 BL14DL4_03468 3338602 3339501 - Epimerase family protein YfhF Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03468 BL14DL4_03469 BL14DL4_03469 BL14DL4_03469 3339570 3340361 + Regulatory protein RecX Modulates RecA activity%3B Belongs to the RecX family gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03469 BL14DL4_03470 BL14DL4_03470 BL14DL4_03470 3340366 3340680 + uncharacterized protein gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03470 BL14DL4_03471 BL14DL4_03471 BL14DL4_03471 3340711 3340881 - hypothetical protein gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03471 BL14DL4_03472 BL14DL4_03472 BL14DL4_03472 3340908 3341027 - Small%2C acid-soluble spore protein Belongs to the SspK family gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03472 BL14DL4_03473 BL14DL4_03473 BL14DL4_03473 3341189 3341458 + uncharacterized protein gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03473 BL14DL4_03474 BL14DL4_03474 arnC arnC 3342163 3343122 + Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase Belongs to the glycosyltransferase 2 family. GtrB subfamily%3B KEGG: gme:Gmet_0885 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03474 BL14DL4_03475 BL14DL4_03475 BL14DL4_03475 3343091 3343492 + hypothetical protein gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03475 BL14DL4_03476 BL14DL4_03476 BL14DL4_03476 3343489 3346074 + uncharacterized protein gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03476 BL14DL4_03477 BL14DL4_03477 BL14DL4_03477 3346071 3347054 - uncharacterized protein May act as a negative regulator for the transcription of yfhQ%2C fabL%2C sspE and yfhP gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03477 BL14DL4_03478 BL14DL4_03478 mutY mutY 3347262 3348347 + putative A/G-specific adenine glycosylase YfhQ Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7%2C8-dihydro-8-oxoguanine%2C 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions (By similarity). Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7%2C8-dihydro-8- oxoguanine (By similarity)%3B Belongs to the Nth/MutY family%3B Contains 1 HhH domain%3B KEGG: bli:BL03038 A/G-specific adenine glycosylase%3B Hydrolyzing N-glycosyl compounds gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03478 BL14DL4_03479 BL14DL4_03479 BL14DL4_03479 3348373 3348597 - uncharacterized protein gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03479 BL14DL4_03480 BL14DL4_03480 phbB phbB 3348680 3349432 + Acetoacetyl-CoA reductase Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It confers resistance to triclosan%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: jag:GJA_3696 acetoacetyl-CoA reductase gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03480 BL14DL4_03481 BL14DL4_03481 BL14DL4_03481 3349501 3349665 + Small%2C acid-soluble spore protein gamma-type SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. These proteins may be involved in dormant spore's high resistance to UV light. Belongs to the gamma-type SASP family gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03481 BL14DL4_03482 BL14DL4_03482 BL14DL4_03482 3349833 3350078 + uncharacterized protein gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03482 BL14DL4_03483 BL14DL4_03483 BL14DL4_03483 3350242 3350772 + UPF0374 protein Belongs to the UPF0374 family gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03483 BL14DL4_03484 BL14DL4_03484 BL14DL4_03484 3350848 3352590 + Putative multidrug export ATP-binding/permease protein YgaD May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain%3B KEGG: bsu:BSU08690 ATP-binding cassette%2C subfamily B%2C bacterial MsbA%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03484 BL14DL4_03485 BL14DL4_03485 BL14DL4_03485 3352721 3353701 + Oligopeptide transport ATP-binding protein OppD Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03485 BL14DL4_03486 BL14DL4_03486 BL14DL4_03486 3353698 3354654 + Macrolide export ATP-binding/permease protein MacB Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03486 BL14DL4_03487 BL14DL4_03487 BL14DL4_03487 3354651 3356249 + Periplasmic dipeptide transport protein Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis. Belongs to the bacterial solute-binding protein 5 family gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03487 BL14DL4_03488 BL14DL4_03488 BL14DL4_03488 3356263 3357264 + Oligopeptide transport system permease protein AppB This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03488 BL14DL4_03489 BL14DL4_03489 BL14DL4_03489 3357277 3358167 + putative D%2CD-dipeptide transport system permease protein DdpC Part of the ABC transporter complex DdpABCDF%2C which is probably involved in D%2CD-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03489 BL14DL4_03490 BL14DL4_03490 BL14DL4_03490 3358197 3359267 - UPF0421 protein YgaE Belongs to the UPF0421 family gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03490 BL14DL4_03491 BL14DL4_03491 BL14DL4_03491 3359520 3360818 - Glutamate-1-semialdehyde 2%2C1-aminomutase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily%3B KEGG: bli:BL03060 glutamate-1-semialdehyde 2%2C1-aminomutase gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03491 BL14DL4_03492 BL14DL4_03492 prxQ prxQ 3360982 3361455 + Peroxiredoxin Belongs to the AhpC/TSA family%3B Contains 1 thioredoxin domain%3B KEGG: cbu:CBU_0963 peroxiredoxin Q/BCP gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03492 BL14DL4_03493 BL14DL4_03493 BL14DL4_03493 3361668 3362105 + Peroxide operon regulator Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA%2C ahpC%2C ahpF%2C the heme biosynthesis operon (hemAXCDBL)%2C fur%2C perR%2C zosA and mrgA. Belongs to the Fur family gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03493 BL14DL4_03494 BL14DL4_03494 BL14DL4_03494 3362154 3362501 - UPF0295 protein Belongs to the UPF0295 family gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03494 BL14DL4_03495 BL14DL4_03495 BL14DL4_03495 3362719 3363603 + uncharacterized protein gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03495 BL14DL4_03496 BL14DL4_03496 BL14DL4_03496 3363891 3365441 + 16S ribosomal RNA rRNA gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03496 BL14DL4_03497 BL14DL4_03497 BL14DL4_03497 3365616 3368546 + 23S ribosomal RNA rRNA gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03497 BL14DL4_03498 BL14DL4_03498 BL14DL4_03498 3368717 3368832 + 5S ribosomal RNA rRNA gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03498 BL14DL4_03499 BL14DL4_03499 BL14DL4_03499 3368842 3368916 + tRNA-Asn tRNA gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03499 BL14DL4_03500 BL14DL4_03500 BL14DL4_03500 3368923 3369014 + tRNA-Ser tRNA gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03500 BL14DL4_03501 BL14DL4_03501 BL14DL4_03501 3369029 3369103 + tRNA-Glu tRNA gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03501 BL14DL4_03502 BL14DL4_03502 BL14DL4_03502 3369221 3369296 + tRNA-Val tRNA gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03502 BL14DL4_03503 BL14DL4_03503 BL14DL4_03503 3369318 3369394 + tRNA-Met tRNA gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03503 BL14DL4_03504 BL14DL4_03504 BL14DL4_03504 3369409 3369485 + tRNA-Asp tRNA gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03504 BL14DL4_03505 BL14DL4_03505 BL14DL4_03505 3369496 3369571 + tRNA-Phe tRNA gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03505 BL14DL4_03506 BL14DL4_03506 BL14DL4_03506 3369575 3369647 + tRNA-Thr tRNA gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03506 BL14DL4_03507 BL14DL4_03507 BL14DL4_03507 3369655 3369739 + tRNA-Tyr tRNA gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03507 BL14DL4_03508 BL14DL4_03508 BL14DL4_03508 3369747 3369820 + tRNA-Trp tRNA gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03508 BL14DL4_03509 BL14DL4_03509 BL14DL4_03509 3369841 3369913 + tRNA-His tRNA gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03509 BL14DL4_03510 BL14DL4_03510 BL14DL4_03510 3369922 3369993 + tRNA-Gln tRNA gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03510 BL14DL4_03511 BL14DL4_03511 BL14DL4_03511 3370047 3370121 + tRNA-Gly tRNA gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03511 BL14DL4_03512 BL14DL4_03512 BL14DL4_03512 3370135 3370205 + tRNA-Cys tRNA gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03512 BL14DL4_03513 BL14DL4_03513 BL14DL4_03513 3370216 3370304 + tRNA-Leu tRNA gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03513 BL14DL4_03514 BL14DL4_03514 BL14DL4_03514 3370319 3370403 + tRNA-Leu tRNA gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03514 BL14DL4_03515 BL14DL4_03515 BL14DL4_03515 3370730 3371770 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02513 response regulator aspartate phosphatase D%3B Acting on ester bonds gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03515 BL14DL4_03516 BL14DL4_03516 BL14DL4_03516 3371825 3371962 + hypothetical protein gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03516 BL14DL4_03517 BL14DL4_03517 BL14DL4_03517 3374304 3374519 + hypothetical protein gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03517 BL14DL4_03518 BL14DL4_03518 BL14DL4_03518 3374492 3374863 + N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03518 BL14DL4_03519 BL14DL4_03519 BL14DL4_03519 3374922 3375260 - hypothetical protein gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03519 BL14DL4_03520 BL14DL4_03520 BL14DL4_03520 3375286 3377010 - Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03520 BL14DL4_03521 BL14DL4_03521 rapE rapE 3377336 3378454 + Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL01908 response regulator aspartate phosphatase E%3B Acting on ester bonds gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03521 BL14DL4_03522 BL14DL4_03522 BL14DL4_03522 3379247 3380572 + Threonine--tRNA ligase Belongs to the class-II aminoacyl-tRNA synthetase family%3B KEGG: pod:PODO_08475 threonyl-tRNA synthetase gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03522 BL14DL4_03523 BL14DL4_03523 aroD aroD 3381425 3382189 + 3-dehydroquinate dehydratase Involved in the third step of the chorismate pathway%2C which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate%3B Belongs to the type-I 3-dehydroquinase family%3B KEGG: bli:BL00001 3-dehydroquinate dehydratase I gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03523 BL14DL4_03524 BL14DL4_03524 thiC thiC 3382595 3384370 + Phosphomethylpyrimidine synthase Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction%3B Belongs to the ThiC family%3B KEGG: bsu:BSU08790 phosphomethylpyrimidine synthase gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03524 BL14DL4_03525 BL14DL4_03525 ssuB ssuB 3384573 3385340 + Aliphatic sulfonates import ATP-binding protein SsuB Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3. A. 1. 17. 2) family%3B Contains 1 ABC transporter domain%3B KEGG: bli:BL03206 sulfonate transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03525 BL14DL4_03526 BL14DL4_03526 BL14DL4_03526 3385361 3386350 + Putative aliphatic sulfonates-binding protein Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein. Belongs to the bacterial solute-binding protein SsuA/TauA family gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03526 BL14DL4_03527 BL14DL4_03527 BL14DL4_03527 3386347 3387183 + Putative aliphatic sulfonates transport permease protein SsuC Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03527 BL14DL4_03528 BL14DL4_03528 ssuD ssuD 3387197 3388327 + Alkanesulfonate monooxygenase Catalyzes the desulfonation of aliphatic sulfonates%3B Belongs to the SsuD family%3B KEGG: rme:Rmet_1371 alkanesulfonate monooxygenase gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03528 BL14DL4_03529 BL14DL4_03529 BL14DL4_03529 3388358 3388816 - putative lipoprotein YgaO gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03529 BL14DL4_03530 BL14DL4_03530 BL14DL4_03530 3388813 3389019 - putative HTH-type transcriptional regulator YgzD Contains 1 HTH cro/C1-type DNA-binding domain gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03530 BL14DL4_03531 BL14DL4_03531 BL14DL4_03531 3389569 3389781 + hypothetical protein gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03531 BL14DL4_03532 BL14DL4_03532 BL14DL4_03532 3389889 3390635 + Polyamine-transporting ATPase Involved in a high affinity multicomponent binding- protein-dependent transport system for choline. Probably responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B Contains 2 CBS domains%3B KEGG: pkc:PKB_2225 spermidine/putrescine transport system ATP-binding protein gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03532 BL14DL4_03533 BL14DL4_03533 BL14DL4_03533 3390732 3392069 + hypothetical protein gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03533 BL14DL4_03534 BL14DL4_03534 BL14DL4_03534 3392059 3392967 + hypothetical protein gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03534 BL14DL4_03535 BL14DL4_03535 BL14DL4_03535 3392964 3393248 + hypothetical protein gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03535 BL14DL4_03536 BL14DL4_03536 BL14DL4_03536 3393356 3393625 + 30S ribosomal protein S14 Binds 16S rRNA%2C required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site%3B Belongs to the ribosomal protein S14P family gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03536 BL14DL4_03537 BL14DL4_03537 BL14DL4_03537 3393768 3393841 + tRNA-Gly tRNA gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03537 BL14DL4_03538 BL14DL4_03538 BL14DL4_03538 3393950 3394579 - uncharacterized protein gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03538 BL14DL4_03539 BL14DL4_03539 queG queG 3394660 3395808 + Epoxyqueuosine reductase Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q)%2C which is a hypermodified base found in the wobble positions of tRNA(Asp)%2C tRNA(Asn)%2C tRNA(His) and tRNA(Tyr)%3B Belongs to the QueG family%3B Contains 2 4Fe-4S ferredoxin-type domains%3B KEGG: bli:BL03196 epoxyqueuosine reductase gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03539 BL14DL4_03540 BL14DL4_03540 BL14DL4_03540 3395872 3396777 + uncharacterized protein gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03540 BL14DL4_03541 BL14DL4_03541 trmL trmL 3396821 3397294 + tRNA (cytidine(34)-2'-O)-methyltransferase Could methylate the ribose at the nucleotide 34 wobble position in tRNA%3B Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily%3B KEGG: gpb:HDN1F_07340 tRNA (cytidine/uridine-2'-O-)-methyltransferase gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03541 BL14DL4_03542 BL14DL4_03542 BL14DL4_03542 3397386 3398000 + uncharacterized protein gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03542 BL14DL4_03543 BL14DL4_03543 BL14DL4_03543 3398015 3398725 + uncharacterized protein gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03543 BL14DL4_03544 BL14DL4_03544 BL14DL4_03544 3398740 3399441 + uncharacterized protein gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03544 BL14DL4_03545 BL14DL4_03545 BL14DL4_03545 3399842 3401737 + Protein PrkA Belongs to the PrkA family gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03545 BL14DL4_03546 BL14DL4_03546 BL14DL4_03546 3401912 3403078 + Stress response UPF0229 protein YhbH Belongs to the UPF0229 family gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03546 BL14DL4_03547 BL14DL4_03547 BL14DL4_03547 3403386 3404018 + Putative efflux system component YhbJ Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03547 BL14DL4_03548 BL14DL4_03548 BL14DL4_03548 3404058 3405647 + Lincomycin resistance protein LmrB Proton-dependent transporter. May mediate the efflux of lincomycin. Belongs to the major facilitator superfamily. EmrB family gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03548 BL14DL4_03549 BL14DL4_03549 BL14DL4_03549 3405665 3406195 + NAD(P)H dehydrogenase (quinone) Contains 1 flavodoxin-like domain%3B KEGG: bsl:A7A1_3824 NAD(P)H dehydrogenase (quinone) gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03549 BL14DL4_03550 BL14DL4_03550 BL14DL4_03550 3406209 3406541 + hypothetical protein gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03550 BL14DL4_03551 BL14DL4_03551 BL14DL4_03551 3407322 3407531 + hypothetical protein gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03551 BL14DL4_03552 BL14DL4_03552 BL14DL4_03552 3407551 3408474 + Monosaccharide-transporting ATPase Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: yen:YE0142 simple sugar transport system ATP-binding protein gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03552 BL14DL4_03553 BL14DL4_03553 BL14DL4_03553 3408467 3409408 + uncharacterized protein gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03553 BL14DL4_03554 BL14DL4_03554 BL14DL4_03554 3409526 3409726 - Cold shock protein CspB Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA%2C and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions%3B Contains 1 CSD (cold-shock) domain gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03554 BL14DL4_03555 BL14DL4_03555 BL14DL4_03555 3410243 3411244 + Methionine import ATP-binding protein MetN Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Methionine importer (TC 3. A. 1. 24) family%3B Contains 1 ABC transporter domain gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03555 BL14DL4_03556 BL14DL4_03556 BL14DL4_03556 3411247 3411897 + D-methionine transport system permease protein MetI Part of the binding-protein-dependent transport system for D-methionine and the toxic methionine analog alpha-methyl- methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03556 BL14DL4_03557 BL14DL4_03557 BL14DL4_03557 3411919 3412737 + D-methionine-binding lipoprotein MetQ This protein is a component of a D-methionine permease%2C a binding protein-dependent%2C ATP-driven transport system%3B Belongs to the NlpA lipoprotein family gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03557 BL14DL4_03558 BL14DL4_03558 BL14DL4_03558 3412864 3414249 + L-cystine uptake protein TcyP Mediates uptake of L-cystine%2C the oxidized form of L- cysteine%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03558 BL14DL4_03559 BL14DL4_03559 BL14DL4_03559 3414295 3414636 - hypothetical protein gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03559 BL14DL4_03560 BL14DL4_03560 BL14DL4_03560 3414684 3416480 - Prolyl oligopeptidase Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1- or -P1'-P2'-COOH) from the free amino or carboxy termini. Prefers substrates composed of bulky%2C hydrophobic amino acids at P1 and P1' positions. Has endopeptidase activity on N- terminally blocked peptide derivatives which contain aromatic amino acid residue at the P1 position. Exopeptidase activity is much higher than its endopeptidase activity%3B Belongs to the peptidase S9 family%3B KEGG: cps:CPS_3511 prolyl oligopeptidase gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03560 BL14DL4_03561 BL14DL4_03561 BL14DL4_03561 3416626 3417186 + Lipoprotein YhcN gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03561 BL14DL4_03562 BL14DL4_03562 BL14DL4_03562 3417302 3418195 + uncharacterized protein gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03562 BL14DL4_03563 BL14DL4_03563 BL14DL4_03563 3418189 3418836 - Spore coat protein F-like protein YhcQ Belongs to the CotF family gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03563 BL14DL4_03564 BL14DL4_03564 BL14DL4_03564 3419508 3421532 + Protein-glutamate O-methyltransferase Contains 1 cheB-type methylesterase domain%3B Contains 1 cheR-type methyltransferase domain%3B KEGG: bae:BATR1942_02185 two-component system%2C chemotaxis family%2C CheB/CheR fusion protein gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03564 BL14DL4_03565 BL14DL4_03565 BL14DL4_03565 3421645 3425265 + 5'-nucleotidase Sugar-nonspecific endonuclease that yields nucleotide 3'-monophosphate products. No 5'-nucleotidase activity was detected%2C using 5'-AMP as the substrate%2C in the presence of diverse divalent metals and with various pH values. In the C-terminal sectio%3B belongs to the 5'- nucleotidase family%3B Contains 1 TNase-like domain%3B KEGG: bha:BH1015 5'-nucleotidase gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03565 BL14DL4_03566 BL14DL4_03566 BL14DL4_03566 3425262 3425852 + Sortase A KEGG: bli:BL03172 sortase A gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03566 BL14DL4_03567 BL14DL4_03567 rluD rluD 3425935 3426852 - 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL03158 23S rRNA pseudouridine1911/1915/1917 synthase gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03567 BL14DL4_03568 BL14DL4_03568 BL14DL4_03568 3426965 3427333 + uncharacterized protein gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03568 BL14DL4_03569 BL14DL4_03569 BL14DL4_03569 3427502 3427927 + CBS domain-containing protein YhcV Contains 2 CBS domains gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03569 BL14DL4_03570 BL14DL4_03570 BL14DL4_03570 3428066 3428728 + uncharacterized protein Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03570 BL14DL4_03571 BL14DL4_03571 BL14DL4_03571 3428750 3430288 + Hydrolase YhcX Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain%3B Contains 1 N-acetyltransferase domain gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03571 BL14DL4_03572 BL14DL4_03572 BL14DL4_03572 3430384 3430518 + hypothetical protein gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03572 BL14DL4_03573 BL14DL4_03573 BL14DL4_03573 3430624 3432252 + Zinc import ATP-binding protein ZnuC Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Zinc importer (TC 3. A. 1. 15. 5) family%3B Contains 1 ABC transporter domain gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03573 BL14DL4_03574 BL14DL4_03574 BL14DL4_03574 3432501 3433301 + putative transporter YrhG Belongs to the FNT transporter (TC 2. A. 44) family gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03574 BL14DL4_03575 BL14DL4_03575 BL14DL4_03575 3433868 3434779 + putative transporter Belongs to the auxin efflux carrier (TC 2. A. 69) family gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03575 BL14DL4_03576 BL14DL4_03576 BL14DL4_03576 3434886 3435878 - putative zinc-type alcohol dehydrogenase-like protein YogA Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03576 BL14DL4_03577 BL14DL4_03577 BL14DL4_03577 3436055 3436612 + Glycerol uptake operon antiterminator regulatory protein Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. May also regulate expression of the glpFK operon gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03577 BL14DL4_03578 BL14DL4_03578 BL14DL4_03578 3436842 3437657 + Glycerol uptake facilitator protein Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane. Belongs to the MIP/aquaporin (TC 1. A. 8) family gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03578 BL14DL4_03579 BL14DL4_03579 glpK glpK 3437700 3439190 + Glycerol kinase Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate%3B Belongs to the FGGY kinase family%3B KEGG: pha:PSHAa0190 glycerol kinase gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03579 BL14DL4_03580 BL14DL4_03580 BL14DL4_03580 3439168 3439362 + hypothetical protein gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03580 BL14DL4_03581 BL14DL4_03581 glpA glpA 3439337 3441004 + Glycerol-3-phosphate dehydrogenase Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family%3B KEGG: bli:BL02902 glycerol-3-phosphate dehydrogenase gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03581 BL14DL4_03582 BL14DL4_03582 BL14DL4_03582 3441189 3442937 + Phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosphate-dependent) Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. the predominant glycolipid found in B. subtilis membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers%2C since glucose-1-phosphate is the precursor of UDP-glucose%2C which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required for biofilm formation. This is likely due to another role of UDP-glucose%2C which might also act as a metabolic signal regulating biofilm formation or may be involved in some unknown biosynthetic pathway essential for biofilm formation%2C e. g. the synthesis of an exopolysaccharide%3B Belongs to the phosphohexose mutase family%3B KEGG: bli:BL02901 phosphoglucomutase gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03582 BL14DL4_03583 BL14DL4_03583 BL14DL4_03583 3443059 3443517 + uncharacterized protein gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03583 BL14DL4_03584 BL14DL4_03584 BL14DL4_03584 3443539 3443736 + putative HTH-type transcriptional regulator Contains 1 HTH cro/C1-type DNA-binding domain gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03584 BL14DL4_03585 BL14DL4_03585 BL14DL4_03585 3443856 3445004 + Histidine kinase Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL02898 two-component system%2C NarL family%2C sensor kinase gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03585 BL14DL4_03586 BL14DL4_03586 BL14DL4_03586 3444992 3445645 + Chemotaxis response regulator protein-glutamate methylesterase Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03586 BL14DL4_03587 BL14DL4_03587 BL14DL4_03587 3445650 3446168 + Azobenzene reductase Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH%2C but not NADH%2C as an electron donor for its activity%3B Belongs to the azoreductase type 2 family%3B KEGG: bli:BL02896 azobenzene reductase gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03587 BL14DL4_03588 BL14DL4_03588 BL14DL4_03588 3446198 3446446 - uncharacterized protein gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03588 BL14DL4_03589 BL14DL4_03589 BL14DL4_03589 3446565 3446969 + uncharacterized protein gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03589 BL14DL4_03590 BL14DL4_03590 BL14DL4_03590 3447000 3447431 - HTH-type transcriptional repressor NsrR Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity%3B Contains 1 HTH rrf2-type DNA-binding domain gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03590 BL14DL4_03591 BL14DL4_03591 yhb1 yhb1 3447689 3448903 + Nitric oxide dioxygenase Is involved in NO detoxification in an aerobic process%2C termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate%2C which protects the cell from various noxious nitrogen compounds. Therefore%2C plays a central role in the inducible response to nitrosative stress%3B In the presence of oxygen and NADH%2C it has NADH oxidase activity%2C which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions%2C it also exhibits nitric oxide reductase and FAD reductase activities. However%2C all these reactions are much lower than NOD activity (By similarity)%3B Belongs to the globin family. Two-domain flavohemoproteins subfamily%3B In the C-terminal sectio%3B belongs to the flavoprotein pyridine nucleotide cytochrome reductase family%3B Contains 1 FAD-binding FR-type domain%3B KEGG: cps:CPS_0848 nitric oxide dioxygenase gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03591 BL14DL4_03592 BL14DL4_03592 BL14DL4_03592 3449208 3450617 + Stage V sporulation protein Appears to be involved in spore cortex formation. To E. coli YcgB gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03592 BL14DL4_03593 BL14DL4_03593 BL14DL4_03593 3451032 3451865 + putative peptidoglycan endopeptidase LytE Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth%3B Belongs to the peptidase C40 family%3B Contains 3 LysM repeats%3B KEGG: bsu:BSU09420 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03593 BL14DL4_03594 BL14DL4_03594 BL14DL4_03594 3451913 3452791 - HTH-type transcriptional regulator CitR Negative regulatory protein for the citA gene for citrate synthase I%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03594 BL14DL4_03595 BL14DL4_03595 BL14DL4_03595 3452902 3453993 + Citrate (Si)-synthase Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. Belongs to the citrate synthase family%3B KEGG: bli:BL02891 citrate synthase gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03595 BL14DL4_03596 BL14DL4_03596 BL14DL4_03596 3454116 3455180 + Quinoprotein glucose dehydrogenase (PQQ%2C quinone) KEGG: tth:TTC0202 quinoprotein glucose dehydrogenase gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03596 BL14DL4_03597 BL14DL4_03597 BL14DL4_03597 3455259 3456128 + putative oxidoreductase YhdF Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL02889 null%3B Oxidoreductases gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03597 BL14DL4_03598 BL14DL4_03598 BL14DL4_03598 3456267 3457625 + Sodium-dependent neutral amino acid transporter B(0)AT2 Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for methionine and for the branched-chain amino acids%2C particularly leucine%2C valine and isoleucine. Mediates the saturable%2C pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2. A. 22) family. SLC6A15 subfamily gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03598 BL14DL4_03599 BL14DL4_03599 gadB gadB 3457647 3459275 + Glutamate decarboxylase Catalyzes the production of GABA%3B Belongs to the group II decarboxylase family%3B KEGG: olu:OSTLU_36228 glutamate decarboxylase gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03599 BL14DL4_03600 BL14DL4_03600 BL14DL4_03600 3459313 3460200 - putative HTH-type transcriptional regulator YdeE Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03600 BL14DL4_03601 BL14DL4_03601 BL14DL4_03601 3460278 3461690 - putative HTH-type transcriptional regulator YdeL In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03601 BL14DL4_03602 BL14DL4_03602 BL14DL4_03602 3461803 3462237 + putative N-acetyltransferase YhdJ Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: reh:H16_B1407 null%3B Transferring groups other than amino-acyl groups gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03602 BL14DL4_03603 BL14DL4_03603 BL14DL4_03603 3462266 3462556 - putative anti-sigma-M factor YhdK gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03603 BL14DL4_03604 BL14DL4_03604 BL14DL4_03604 3462544 3463614 - putative anti-sigma-M factor YhdL gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03604 BL14DL4_03605 BL14DL4_03605 BL14DL4_03605 3463607 3464098 - RNA polymerase sigma factor SigM Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt%2C acid and ethanol stress. Belongs to the sigma-70 factor family. ECF subfamily gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03605 BL14DL4_03606 BL14DL4_03606 BL14DL4_03606 3464388 3464930 - uncharacterized protein gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03606 BL14DL4_03607 BL14DL4_03607 BL14DL4_03607 3465051 3465323 + hypothetical protein gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03607 BL14DL4_03608 BL14DL4_03608 BL14DL4_03608 3465389 3465988 + 1-acylglycerol-3-phosphate O-acyltransferase Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family%3B KEGG: blh:BaLi_c11330 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03608 BL14DL4_03609 BL14DL4_03609 BL14DL4_03609 3465945 3466088 + hypothetical protein gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03609 BL14DL4_03610 BL14DL4_03610 BL14DL4_03610 3466150 3466515 + Inner membrane protein To E. coli YhaH gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03610 BL14DL4_03611 BL14DL4_03611 BL14DL4_03611 3466546 3467823 - Bile acid-CoA:amino acid N-acyltransferase Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester%2C either in peroxisomes (primary bile acids deriving from the cholesterol pathway)%2C or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids%2C or both. The conjugation increases the detergent properties of bile acids in the intestine%2C which facilitates lipid and fat-soluble vitamin absorption. In turn%2C bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro%2C catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH)%2C and conjugates glycine to these acyl-CoAs (By similarity)%3B Belongs to the C/M/P thioester hydrolase family gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03611 BL14DL4_03612 BL14DL4_03612 BL14DL4_03612 3467820 3468416 - putative HTH-type transcriptional regulator YvkB Contains 1 HTH tetR-type DNA-binding domain gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03612 BL14DL4_03613 BL14DL4_03613 BL14DL4_03613 3468547 3469866 - UPF0053 protein YhdP Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03613 BL14DL4_03614 BL14DL4_03614 BL14DL4_03614 3469927 3470352 - HTH-type transcriptional regulator CueR Transcriptional activator of the copZA operon%3B Contains 1 HTH merR-type DNA-binding domain gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03614 BL14DL4_03615 BL14DL4_03615 BL14DL4_03615 3470456 3470626 - hypothetical protein gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03615 BL14DL4_03616 BL14DL4_03616 BL14DL4_03616 3470667 3472040 + UPF0053 protein YhdT Belongs to the UPF0053 family%3B Contains 2 CBS domains%3B Contains 1 DUF21 domain gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03616 BL14DL4_03617 BL14DL4_03617 BL14DL4_03617 3472138 3472539 + hypothetical protein gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03617 BL14DL4_03618 BL14DL4_03618 BL14DL4_03618 3472748 3473035 + hypothetical protein gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03618 BL14DL4_03619 BL14DL4_03619 BL14DL4_03619 3472998 3473675 + N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03619 BL14DL4_03620 BL14DL4_03620 BL14DL4_03620 3473845 3474201 - Putative fluoride ion transporter CrcB Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03620 BL14DL4_03621 BL14DL4_03621 BL14DL4_03621 3474198 3474596 - Putative fluoride ion transporter CrcB Important for reducing fluoride concentration in the cell%2C thus reducing its toxicity%3B Belongs to the CrcB (TC 9. B. 71) family gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03621 BL14DL4_03622 BL14DL4_03622 BL14DL4_03622 3474612 3475316 - Glycerophosphodiester phosphodiesterase Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols%3B Belongs to the glycerophosphoryl diester phosphodiesterase family%3B Contains 1 GP-PDE domain%3B KEGG: fau:Fraau_3181 glycerophosphoryl diester phosphodiesterase gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03622 BL14DL4_03623 BL14DL4_03623 BL14DL4_03623 3475508 3475615 + uncharacterized protein gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03623 BL14DL4_03624 BL14DL4_03624 BL14DL4_03624 3475799 3476875 + putative MscS family protein YhdY May play a role in resistance to osmotic downshock%3B Belongs to the MscS (TC 1. A. 23) family gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03624 BL14DL4_03625 BL14DL4_03625 npdA npdA 3476904 3477653 + NAD-dependent protein deacetylase NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form%3B Belongs to the sirtuin family. Class U subfamily%3B Contains 1 deacetylase sirtuin-type domain%3B KEGG: bli:BL02876 NAD-dependent deacetylase%3B In linear amides gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03625 BL14DL4_03626 BL14DL4_03626 BL14DL4_03626 3477696 3478190 - hypothetical protein gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03626 BL14DL4_03627 BL14DL4_03627 BL14DL4_03627 3478325 3479236 - Chitin deacetylase Belongs to the polysaccharide deacetylase family%3B KEGG: bcz:BCZK1658 chitin deacetylase gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03627 BL14DL4_03628 BL14DL4_03628 BL14DL4_03628 3479534 3480385 + D-amino-acid transaminase Acts on the D-isomers of alanine%2C leucine%2C aspartate%2C glutamate%2C aminobutyrate%2C norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first%2C transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate%2C which are essential bacterial cell wall components (By similarity)%3B Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL02875 D-alanine transaminase gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03628 BL14DL4_03629 BL14DL4_03629 BL14DL4_03629 3480424 3481782 - Na(+)/H(+) antiporter NhaC Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion%3B Belongs to the NhaC Na(+)/H(+) (TC 2. A. 35) antiporter family gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03629 BL14DL4_03630 BL14DL4_03630 galM galM 3482018 3482998 + Aldose 1-epimerase Belongs to the aldose epimerase family%3B KEGG: bli:BL02874 aldose 1-epimerase gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03630 BL14DL4_03631 BL14DL4_03631 BL14DL4_03631 3483014 3483490 - uncharacterized protein gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03631 BL14DL4_03632 BL14DL4_03632 BL14DL4_03632 3483564 3485498 - hypothetical protein gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03632 BL14DL4_03633 BL14DL4_03633 BL14DL4_03633 3485498 3487351 - hypothetical protein gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03633 BL14DL4_03634 BL14DL4_03634 BL14DL4_03634 3488560 3489060 - Stress response protein NhaX Belongs to the universal stress protein A family gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03634 BL14DL4_03635 BL14DL4_03635 BL14DL4_03635 3489581 3491335 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheI Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03635 BL14DL4_03636 BL14DL4_03636 BL14DL4_03636 3491332 3493350 + putative multidrug resistance ABC transporter ATP-binding/permease protein YheH Involved in the transport of four structurally unrelated drugs%2C including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03636 BL14DL4_03637 BL14DL4_03637 BL14DL4_03637 3493370 3494017 - uncharacterized protein gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03637 BL14DL4_03638 BL14DL4_03638 BL14DL4_03638 3494014 3494157 - hypothetical protein gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03638 BL14DL4_03639 BL14DL4_03639 BL14DL4_03639 3494327 3494530 - Small%2C acid-soluble spore protein SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03639 BL14DL4_03640 BL14DL4_03640 BL14DL4_03640 3494766 3494990 + hypothetical protein gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03640 BL14DL4_03641 BL14DL4_03641 BL14DL4_03641 3495036 3496142 - Phosphonates import ATP-binding protein PhnC Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03641 BL14DL4_03642 BL14DL4_03642 BL14DL4_03642 3496258 3497139 - uncharacterized protein gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03642 BL14DL4_03643 BL14DL4_03643 BL14DL4_03643 3497158 3497367 - uncharacterized protein gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03643 BL14DL4_03644 BL14DL4_03644 BL14DL4_03644 3497520 3498878 - Endospore coat-associated protein YheD Involved in sporulation%3B Belongs to the YheC/YheD family gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03644 BL14DL4_03645 BL14DL4_03645 BL14DL4_03645 3498875 3499960 - Endospore coat-associated protein YheC Involved in sporulation%3B Belongs to the YheC/YheD family gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03645 BL14DL4_03646 BL14DL4_03646 BL14DL4_03646 3500290 3501420 + UPF0754 membrane protein Belongs to the UPF0754 family gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03646 BL14DL4_03647 BL14DL4_03647 BL14DL4_03647 3501543 3501896 + UPF0342 protein Belongs to the UPF0342 family gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03647 BL14DL4_03648 BL14DL4_03648 BL14DL4_03648 3502343 3503206 + Stress response protein YhaX gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03648 BL14DL4_03649 BL14DL4_03649 BL14DL4_03649 3503236 3504855 + Coproporphyrinogen dehydrogenase Involved in the biosynthesis of porphyrin-containing compound%3B Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemZ subfamily%3B KEGG: bli:BL02869 oxygen-independent coproporphyrinogen III oxidase gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03649 BL14DL4_03650 BL14DL4_03650 BL14DL4_03650 3504937 3506148 - K(+)/H(+) antiporter YhaU Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of KhtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium or lithium ions%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03650 BL14DL4_03651 BL14DL4_03651 BL14DL4_03651 3506155 3506652 - K(+)/H(+) antiporter subunit KhtT Modulates the activity of the potassium/proton antiporter YhaU. The transporter is composed of the integral membrane protein YhaU and the regulatory protein KhtT%3B Contains 1 RCK C-terminal domain gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03651 BL14DL4_03652 BL14DL4_03652 BL14DL4_03652 3506717 3507046 - hypothetical protein gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03652 BL14DL4_03653 BL14DL4_03653 liuC liuC 3507247 3508023 + Methylglutaconyl-CoA hydratase Belongs to the enoyl-CoA hydratase/isomerase family%3B KEGG: mro:MROS_2743 methylglutaconyl-CoA hydratase gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03653 BL14DL4_03654 BL14DL4_03654 BL14DL4_03654 3508150 3509268 + Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL02867 response regulator aspartate phosphatase I%3B Acting on ester bonds gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03654 BL14DL4_03655 BL14DL4_03655 BL14DL4_03655 3509258 3509395 + hypothetical protein gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03655 BL14DL4_03656 BL14DL4_03656 BL14DL4_03656 3509400 3509678 + hypothetical protein gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03656 BL14DL4_03657 BL14DL4_03657 BL14DL4_03657 3509753 3509938 - uncharacterized protein gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03657 BL14DL4_03658 BL14DL4_03658 rbsA rbsA 3510056 3510952 + Monosaccharide-transporting ATPase Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3. A. 1. 9. 1) family%3B Contains 1 ABC transporter domain%3B KEGG: sod:Sant_0208 ribose transport system ATP-binding protein gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03658 BL14DL4_03659 BL14DL4_03659 BL14DL4_03659 3510945 3512213 + uncharacterized protein To M. jannaschii MJ1024 gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03659 BL14DL4_03660 BL14DL4_03660 BL14DL4_03660 3512333 3513559 + putative metallophosphoesterase YhaO Belongs to the metallophosphoesterase superfamily gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03660 BL14DL4_03661 BL14DL4_03661 BL14DL4_03661 3513573 3516539 + uncharacterized protein gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03661 BL14DL4_03662 BL14DL4_03662 cbf1 cbf1 3516589 3517533 + 3'-5' exoribonuclease YhaM Shows a 3'-5' exoribonuclease activity%3B Belongs to the YhaM family%3B Contains 1 HD domain%3B Contains 1 OB DNA-binding domain%3B KEGG: bsu:BSU09930 3'-5' exoribonuclease%3B Acting on ester bonds gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03662 BL14DL4_03663 BL14DL4_03663 BL14DL4_03663 3517602 3517835 + Sporulation protein YhaL Required for efficient sporulation gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03663 BL14DL4_03664 BL14DL4_03664 BL14DL4_03664 3517881 3518741 - Peptidylprolyl isomerase Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo%3B Belongs to the PrsA family%3B Contains 1 PpiC domain%3B KEGG: bsu:BSU09950 foldase protein PrsA gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03664 BL14DL4_03665 BL14DL4_03665 BL14DL4_03665 3519119 3519217 + hypothetical protein gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03665 BL14DL4_03666 BL14DL4_03666 BL14DL4_03666 3519564 3520079 - putative membrane protein YhaJ gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03666 BL14DL4_03667 BL14DL4_03667 BL14DL4_03667 3520293 3520640 + uncharacterized protein gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03667 BL14DL4_03668 BL14DL4_03668 BL14DL4_03668 3520637 3521257 - HTH-type transcriptional regulator Hpr Negative regulator of protease production and sporulation%3B Contains 1 HTH marR-type DNA-binding domain gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03668 BL14DL4_03669 BL14DL4_03669 BL14DL4_03669 3521451 3521807 - putative membrane protein YhaH gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03669 BL14DL4_03670 BL14DL4_03670 BL14DL4_03670 3521969 3522160 + putative membrane protein YhzF gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03670 BL14DL4_03671 BL14DL4_03671 BL14DL4_03671 3522251 3522778 - putative tryptophan transport protein Probably involved in tryptophan uptake. Belongs to the TrpP transporter family gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03671 BL14DL4_03672 BL14DL4_03672 serC serC 3522921 3524042 - Phosphoserine transaminase Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine%3B Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily%3B KEGG: bsu:BSU10020 phosphoserine aminotransferase gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03672 BL14DL4_03673 BL14DL4_03673 BL14DL4_03673 3524193 3524612 - Protein HitA Contains 1 HIT domain gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03673 BL14DL4_03674 BL14DL4_03674 BL14DL4_03674 3524855 3525877 + Ribose import ATP-binding protein RbsA Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Ribose importer (TC 3. A. 1. 2. 1) family%3B Contains 2 ABC transporter domains%3B KEGG: sds:SDEG_0568 putative glutamine transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03674 BL14DL4_03675 BL14DL4_03675 BL14DL4_03675 3525870 3527093 + Protein EcsB Presumed to form part of an ABC-transporter%2C it may form a transport channel gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03675 BL14DL4_03676 BL14DL4_03676 BL14DL4_03676 3527146 3527856 + Protein EcsC gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03676 BL14DL4_03677 BL14DL4_03677 BL14DL4_03677 3527877 3529109 - Putative amidohydrolase YhaA Belongs to the peptidase M20A family%3B KEGG: tep:TepRe1_0059 amidohydrolase%3B In linear amides gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03677 BL14DL4_03678 BL14DL4_03678 BL14DL4_03678 3529191 3530564 - putative membrane protein YhfA gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03678 BL14DL4_03679 BL14DL4_03679 BL14DL4_03679 3530673 3531176 - Heme-degrading monooxygenase HmoB Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase%2C with subsequent release of free iron%3B Belongs to the antibiotic biosynthesis monooxygenase family%3B Contains 1 ABM domain gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03679 BL14DL4_03680 BL14DL4_03680 BL14DL4_03680 3531309 3533447 + Penicillin-binding protein 1F Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall. In the N-terminal sectio%3B belongs to the glycosyltransferase 51 family%3B In the C-terminal sectio%3B belongs to the transpeptidase family%3B KEGG: bli:BL01071 penicillin-binding protein 2A%3B Peptidoglycan glycosyltransferase gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03680 BL14DL4_03681 BL14DL4_03681 hemE hemE 3533573 3534634 + Uroporphyrinogen decarboxylase Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III%3B Belongs to the uroporphyrinogen decarboxylase family%3B KEGG: bli:BL01072 uroporphyrinogen decarboxylase gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03681 BL14DL4_03682 BL14DL4_03682 BL14DL4_03682 3534708 3535646 + Protoporphyrin ferrochelatase Catalyzes the ferrous insertion into protoporphyrin IX%3B Belongs to the ferrochelatase family%3B KEGG: bsu:BSU10130 ferrochelatase gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03682 BL14DL4_03683 BL14DL4_03683 ppoX ppoX 3535662 3537074 + Protoporphyrinogen oxidase Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III%3B Belongs to the protoporphyrinogen oxidase family%3B KEGG: bli:BL01074 oxygen-dependent protoporphyrinogen oxidase gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03683 BL14DL4_03684 BL14DL4_03684 BL14DL4_03684 3537271 3537843 + putative HTH-type transcriptional regulator YhgD Contains 1 HTH tetR-type DNA-binding domain gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03684 BL14DL4_03685 BL14DL4_03685 BL14DL4_03685 3537915 3540077 + uncharacterized protein To L. lactis phage infection protein (PIP) gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03685 BL14DL4_03686 BL14DL4_03686 fabH fabH 3540135 3541130 - Beta-ketoacyl-[acyl-carrier-protein] synthase III Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids%3B Belongs to the FabH family%3B KEGG: bli:BL01107 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03686 BL14DL4_03687 BL14DL4_03687 BL14DL4_03687 3541237 3542274 + Cellulase Belongs to the peptidase M42 family%3B KEGG: tpe:Tpen_0002 endoglucanase gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03687 BL14DL4_03688 BL14DL4_03688 BL14DL4_03688 3542353 3542550 - hypothetical protein gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03688 BL14DL4_03689 BL14DL4_03689 BL14DL4_03689 3542712 3543998 - Proton/sodium-glutamate symport protein This carrier protein is part of the Na(+)-dependent%2C binding-protein-independent glutamate-aspartate transport system%3B Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2. A. 23) family gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03689 BL14DL4_03690 BL14DL4_03690 BL14DL4_03690 3544305 3544439 - uncharacterized protein gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03690 BL14DL4_03691 BL14DL4_03691 BL14DL4_03691 3544596 3545330 + putative metallo-hydrolase YhfI Belongs to the metallo-beta-lactamase superfamily gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03691 BL14DL4_03692 BL14DL4_03692 BL14DL4_03692 3545349 3546338 + Lipoate--protein ligase Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate%3B Belongs to the LplA family%3B Contains 1 BPL/LPL catalytic domain%3B KEGG: bsu:BSU10250 lipoate-protein ligase A gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03692 BL14DL4_03693 BL14DL4_03693 BL14DL4_03693 3546501 3548042 + Long-chain-fatty-acid--CoA ligase Involved in the degradation of long-chain fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01080 long-chain acyl-CoA synthetase gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03693 BL14DL4_03694 BL14DL4_03694 BL14DL4_03694 3548013 3548480 - hypothetical protein gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03694 BL14DL4_03695 BL14DL4_03695 BL14DL4_03695 3548587 3549138 + HTH-type transcriptional regulator SutR Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB%2C fliZ%2C cysE%2C ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes%3B Contains 1 HTH cro/C1-type DNA-binding domain gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03695 BL14DL4_03696 BL14DL4_03696 BL14DL4_03696 3549151 3549867 + putative membrane protein Belongs to the AzlC family gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03696 BL14DL4_03697 BL14DL4_03697 BL14DL4_03697 3549860 3550171 + hypothetical protein gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03697 BL14DL4_03698 BL14DL4_03698 BL14DL4_03698 3550243 3551499 + Ste24 endopeptidase Belongs to the peptidase M48B family%3B KEGG: tte:TTE0991 STE24 endopeptidase gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03698 BL14DL4_03699 BL14DL4_03699 BL14DL4_03699 3551557 3552696 - Subtilisin Subtilisin is an extracellular alkaline serine protease%2C it catalyzes the hydrolysis of proteins and peptide amides. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL01111 subtilisin gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03699 BL14DL4_03700 BL14DL4_03700 BL14DL4_03700 3553107 3554006 + putative transporter YdeD Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03700 BL14DL4_03701 BL14DL4_03701 BL14DL4_03701 3554114 3555091 + Putative ABC transporter substrate-binding lipoprotein YhfQ Belongs to the bacterial solute-binding protein 8 family%3B Contains 1 Fe/B12 periplasmic-binding domain gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03701 BL14DL4_03702 BL14DL4_03702 BL14DL4_03702 3555174 3556172 + Iron(3+)-hydroxamate import system permease protein FhuG Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03702 BL14DL4_03703 BL14DL4_03703 BL14DL4_03703 3556172 3557200 + Fe(3+)-citrate import system permease protein YfmD Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable)%3B Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03703 BL14DL4_03704 BL14DL4_03704 BL14DL4_03704 3557213 3557785 - putative phosphatase PhoE Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity%3B Belongs to the phosphoglycerate mutase family. GpmB subfamily gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03704 BL14DL4_03705 BL14DL4_03705 BL14DL4_03705 3558070 3559362 - Heme-based aerotactic transducer HemAT Heme-containing signal transducer responsible for aerotaxis%2C the migratory response toward or away from oxygen%3B Contains 1 methyl-accepting transducer domain gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03705 BL14DL4_03706 BL14DL4_03706 BL14DL4_03706 3559469 3560998 - Putative Rieske 2Fe-2S iron-sulfur protein YhfW Contains 1 Rieske domain%3B KEGG: ctc:CTC00417 null%3B With NAD(+) or NADP(+) as acceptor gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03706 BL14DL4_03707 BL14DL4_03707 BL14DL4_03707 3561139 3561996 + putative oxidoreductase YhxC Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi01117 null%3B Oxidoreductases gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03707 BL14DL4_03708 BL14DL4_03708 BL14DL4_03708 3562062 3562295 - uncharacterized protein gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03708 BL14DL4_03709 BL14DL4_03709 BL14DL4_03709 3562568 3563146 + Competence transcription factor Intermediate regulatory gene required for the expression of the late competence genes comC%2C comE%2C comG and the bdbDC operon. Receives signals from SrfA%2C and possibly other regulatory COM genes%2C and transduces these signals to the late COM genes gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03709 BL14DL4_03710 BL14DL4_03710 BL14DL4_03710 3563140 3563505 - uncharacterized protein gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03710 BL14DL4_03711 BL14DL4_03711 BL14DL4_03711 3563714 3564325 + putative membrane protein YhjE gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03711 BL14DL4_03712 BL14DL4_03712 BL14DL4_03712 3564338 3564856 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bli:BL01092 signal peptidase I gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03712 BL14DL4_03713 BL14DL4_03713 BL14DL4_03713 3565011 3566786 - Minor extracellular protease Epr Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL01118 minor extracellular protease Epr%3B Serine endopeptidases gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03713 BL14DL4_03714 BL14DL4_03714 BL14DL4_03714 3567161 3568402 + putative sulfoacetate transporter SauU May transport sulfoacetate into the cell%3B Belongs to the major facilitator superfamily gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03714 BL14DL4_03715 BL14DL4_03715 BL14DL4_03715 3568431 3570044 - Purine catabolism regulatory protein Activates the expression of pucFG%2C pucH%2C pucI%2C pucJKLM and guaD%2C while it represses pucABCDE and its own expression%3B Belongs to the CdaR family gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03715 BL14DL4_03716 BL14DL4_03716 BL14DL4_03716 3570202 3570432 + hypothetical protein gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03716 BL14DL4_03717 BL14DL4_03717 dpyS dpyS 3570873 3572237 + Dihydropyrimidinase Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring%3B Belongs to the DHOase family. Allantoinase subfamily%3B KEGG: mey:TM49_03535 dihydropyrimidinase gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03717 BL14DL4_03718 BL14DL4_03718 BL14DL4_03718 3572905 3573994 + Allantoate deiminase%3B nonfunctional due to frameshift pseudo gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03718 BL14DL4_03719 BL14DL4_03719 ylbA ylbA 3574018 3574806 + (S)-ureidoglycine aminohydrolase Involved in the catabolism of purine nucleotides. Catalyzes the second%2C stereospecific hydrolysis reaction of the allantoin degradation pathway%2C producing S-ureidoglycolate and ammonia from S-ureidoglycine%3B Belongs to the UGHY family%3B KEGG: bli:BL01096 (S)-ureidoglycine aminohydrolase gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03719 BL14DL4_03720 BL14DL4_03720 allD allD 3574822 3575850 + Ureidoglycolate dehydrogenase (NAD(+)) Involved in the anaerobic utilization of allantoin. Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: bli:BL01097 ureidoglycolate dehydrogenase (NAD+) gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03720 BL14DL4_03721 BL14DL4_03721 BL14DL4_03721 3575874 3576923 + Ureidoglycolate dehydrogenase (NAD(+)) Involved in the anaerobic utilization of allantoin. Belongs to the LDH2/MDH2 oxidoreductase family%3B KEGG: yin:CH53_61 ureidoglycolate dehydrogenase (NAD+) gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03721 BL14DL4_03722 BL14DL4_03722 BL14DL4_03722 3576941 3578698 + uncharacterized protein To E. coli FdrA and some%2C to bacterial SucD gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03722 BL14DL4_03723 BL14DL4_03723 BL14DL4_03723 3578698 3579963 + uncharacterized protein To E. coli YlbE gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03723 BL14DL4_03724 BL14DL4_03724 BL14DL4_03724 3579960 3580730 + hypothetical protein gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03724 BL14DL4_03725 BL14DL4_03725 BL14DL4_03725 3580736 3581668 + Carbamate kinase Belongs to the carbamate kinase family%3B KEGG: bli:BL01102 carbamate kinase gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03725 BL14DL4_03726 BL14DL4_03726 BL14DL4_03726 3581884 3583137 + putative sugar efflux transporter Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites%3B Belongs to the major facilitator superfamily. SotB (TC 2. A. 1. 2) family gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03726 BL14DL4_03727 BL14DL4_03727 rapG rapG 3583789 3584889 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bli:BL01363 response regulator aspartate phosphatase G%3B Acting on ester bonds gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03727 BL14DL4_03728 BL14DL4_03728 BL14DL4_03728 3584889 3585005 + hypothetical protein gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03728 BL14DL4_03729 BL14DL4_03729 BL14DL4_03729 3585860 3586387 - hypothetical protein gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03729 BL14DL4_03730 BL14DL4_03730 BL14DL4_03730 3586493 3586984 + hypothetical protein gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03730 BL14DL4_03731 BL14DL4_03731 BL14DL4_03731 3587242 3588279 + HTH-type transcriptional regulator EbgR Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. Contains 1 HTH lacI-type DNA-binding domain gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03731 BL14DL4_03732 BL14DL4_03732 BL14DL4_03732 3588393 3589646 + Putative binding protein MsmE Probably part of an ABC transporter complex. Belongs to the bacterial solute-binding protein 1 family gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03732 BL14DL4_03733 BL14DL4_03733 BL14DL4_03733 3589686 3590606 + Putative ABC transporter permease protein AmyD Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03733 BL14DL4_03734 BL14DL4_03734 BL14DL4_03734 3590607 3591437 + Putative ABC transporter permease protein AmyC Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family%3B Contains 1 ABC transmembrane type-1 domain gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03734 BL14DL4_03735 BL14DL4_03735 melA melA 3591468 3592766 + Alpha-galactosidase Belongs to the glycosyl hydrolase 4 family%3B KEGG: dsh:Dshi_1245 alpha-galactosidase gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03735 BL14DL4_03736 BL14DL4_03736 BL14DL4_03736 3592791 3593909 - uncharacterized protein Belongs to the AbrB family gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03736 BL14DL4_03737 BL14DL4_03737 BL14DL4_03737 3594155 3594388 + Protein CotJA gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03737 BL14DL4_03738 BL14DL4_03738 BL14DL4_03738 3594394 3594657 + Protein CotJB gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03738 BL14DL4_03739 BL14DL4_03739 BL14DL4_03739 3594679 3595248 + Protein CotJC The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat. Belongs to the manganese catalase family gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03739 BL14DL4_03740 BL14DL4_03740 BL14DL4_03740 3595292 3596911 - Long-chain-fatty-acid--CoA ligase Involved in the catabolism of the rings C and D of cholesterol. Catalyzes the ATP-dependent CoA thioesterification of 3aalpha-H-4alpha(3'-propanoate)-7abeta-methylhexahydro-1%2C5- indanedione (HIP)%3B Belongs to the ATP-dependent AMP-binding enzyme family%3B KEGG: bli:BL01325 long-chain acyl-CoA synthetase gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03740 BL14DL4_03741 BL14DL4_03741 BL14DL4_03741 3596963 3597511 - putative MFS-type transporter YhjO Belongs to the major facilitator superfamily gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03741 BL14DL4_03742 BL14DL4_03742 BL14DL4_03742 3597752 3598993 - hypothetical protein gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03742 BL14DL4_03743 BL14DL4_03743 BL14DL4_03743 3599076 3600443 - Heme sensor protein HssS Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR. HssR/HssS activates the expression of hrtAB%2C an efflux pump%2C in response to extracellular heme%2C hemin%2C hemoglobin or blood (By similarity)%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL01322 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03743 BL14DL4_03744 BL14DL4_03744 BL14DL4_03744 3600440 3601114 - Transcriptional regulatory protein WalR Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis%2C biofilm formation and cell wall metabolism%3B Contains 1 OmpR/PhoB-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03744 BL14DL4_03745 BL14DL4_03745 BL14DL4_03745 3601204 3601644 - uncharacterized protein gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03745 BL14DL4_03746 BL14DL4_03746 BL14DL4_03746 3601848 3602642 + Putative ABC transporter substrate-binding lipoprotein YvgL Belongs to the bacterial solute-binding protein 1 family gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03746 BL14DL4_03747 BL14DL4_03747 BL14DL4_03747 3602651 3603307 + Putative molybdenum transport system permease protein YvgM could be part of the binding-protein-dependent transport system for molybdenu%3B probably responsible for the translocation of the substrate across the membrane%3B Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03747 BL14DL4_03748 BL14DL4_03748 addB addB 3603417 3606917 + ATP-dependent helicase/deoxyribonuclease subunit The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has 5' -> 3' nuclease activity%3B Belongs to the helicase family. AddB/RexB type 1 subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bli:BL01351 ATP-dependent helicase/nuclease subunit B%3B Acting on ester bonds gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03748 BL14DL4_03749 BL14DL4_03749 addA addA 3606904 3610596 + ATP-dependent helicase/nuclease subunit The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent%2C dual-direction single-stranded exonuclease%3B this subunit has the helicase and 3' -> 5' nuclease activities%3B Belongs to the helicase family. AddA subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bli:BL01350 ATP-dependent helicase/nuclease subunit A%3B Acting on ester bonds gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03749 BL14DL4_03750 BL14DL4_03750 BL14DL4_03750 3610662 3611843 + Nuclease SbcCD subunit SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SbcD family gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03750 BL14DL4_03751 BL14DL4_03751 BL14DL4_03751 3611840 3615232 + Nuclease SbcCD subunit SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)%3B Belongs to the SMC family. SbcC subfamily gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03751 BL14DL4_03752 BL14DL4_03752 BL14DL4_03752 3615276 3615494 - putative spore germination protein GerPF Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03752 BL14DL4_03753 BL14DL4_03753 BL14DL4_03753 3615550 3615933 - putative spore germination protein GerPE gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03753 BL14DL4_03754 BL14DL4_03754 BL14DL4_03754 3615930 3616112 - putative spore germination protein GerPD gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03754 BL14DL4_03755 BL14DL4_03755 BL14DL4_03755 3616109 3616714 - putative spore germination protein GerPC gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03755 BL14DL4_03756 BL14DL4_03756 BL14DL4_03756 3616735 3616977 - putative spore germination protein GerPB gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03756 BL14DL4_03757 BL14DL4_03757 BL14DL4_03757 3616989 3617210 - putative spore germination protein GerPA Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability%2C which allows the access of germinants to their receptor. Belongs to the GerPA/GerPF family gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03757 BL14DL4_03758 BL14DL4_03758 BL14DL4_03758 3617392 3617685 + uncharacterized protein gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03758 BL14DL4_03759 BL14DL4_03759 BL14DL4_03759 3617767 3617949 - Aspartyl-phosphate phosphatase YisI Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03759 BL14DL4_03760 BL14DL4_03760 BL14DL4_03760 3618113 3619186 - Inner spore coat protein Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides on the spore surface%3B Belongs to the CotH family gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03760 BL14DL4_03761 BL14DL4_03761 BL14DL4_03761 3619352 3619822 + hypothetical protein gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03761 BL14DL4_03762 BL14DL4_03762 BL14DL4_03762 3619975 3620880 + Acylpyruvate hydrolase Belongs to the FAH family%3B KEGG: fal:FRAAL6170 acylpyruvate hydrolase gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03762 BL14DL4_03763 BL14DL4_03763 BL14DL4_03763 3620896 3621006 + hypothetical protein gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03763 BL14DL4_03764 BL14DL4_03764 rsgA rsgA 3621150 3622202 + Putative ribosome bioproteinis GTPase RsgA May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bli:BL01344 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03764 BL14DL4_03765 BL14DL4_03765 BL14DL4_03765 3622222 3622692 + UPF0344 protein Belongs to the UPF0344 family gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03765 BL14DL4_03766 BL14DL4_03766 BL14DL4_03766 3622732 3623298 - uncharacterized protein gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03766 BL14DL4_03767 BL14DL4_03767 BL14DL4_03767 3623463 3625304 + Asparagine synthase (glutamine-hydrolyzing) Asparagine synthetase involved in sporulation. Belongs to the asparagine synthetase family%3B Contains 1 glutamine amidotransferase type-2 domain%3B KEGG: ppw:PputW619_2683 asparagine synthase (glutamine-hydrolysing) gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03767 BL14DL4_03768 BL14DL4_03768 BL14DL4_03768 3625436 3626815 - Putative ammonium transporter Belongs to the ammonia transporter channel (TC 1. A. 11. 2) family gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03768 BL14DL4_03769 BL14DL4_03769 BL14DL4_03769 3626821 3627210 - Nitrogen regulatory protein P-II In nitrogen-limiting conditions%2C when the ratio of Gln to 2-ketoglutarate decreases%2C P-II is uridylylated to P-II-UMP. P- II-UMP allows the deadenylation of glutamine synthetase (GS)%2C thus activating the enzyme. Conversely%2C in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate%2C the transcriptional activator of glnA. When P-II is uridylylated to P- II-UMP%2C these events are reversed (By similarity)%3B Belongs to the P(II) protein family gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03769 BL14DL4_03770 BL14DL4_03770 BL14DL4_03770 3627413 3628753 - putative transporter YisQ Belongs to the multi antimicrobial extrusion (MATE) (TC 2. A. 66. 1) family gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03770 BL14DL4_03771 BL14DL4_03771 BL14DL4_03771 3628875 3629738 + putative HTH-type transcriptional regulator YisR Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03771 BL14DL4_03772 BL14DL4_03772 BL14DL4_03772 3629767 3630324 + Putative ribosomal N-acetyltransferase YdaF Putative N-acetyltransferase. May act on ribosomal proteins (Potential)%3B Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1895 null%3B Transferring groups other than amino-acyl groups gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03772 BL14DL4_03773 BL14DL4_03773 BL14DL4_03773 3630381 3631424 + HTH-type transcriptional regulator DegA Involved in the control of degradation of B. subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease. Contains 1 HTH lacI-type DNA-binding domain gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03773 BL14DL4_03774 BL14DL4_03774 iolX iolX 3631592 3632620 + Scyllo-inositol 2-dehydrogenase (NAD(+)) Catalyzes the NAD(+)-dependent oxidation of scyllo- inositol to 2%2C4%2C6/3%2C5-pentahydroxycyclohexanone (scyllo-inosose)%3B Belongs to the Gfo/Idh/MocA family%3B KEGG: bli:BL01338 scyllo-inositol 2-dehydrogenase (NAD+) gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03774 BL14DL4_03775 BL14DL4_03775 BL14DL4_03775 3633332 3633335 - Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03775 BL14DL4_03776 BL14DL4_03776 BL14DL4_03776 3633835 3634953 - hypothetical protein gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03776 BL14DL4_03777 BL14DL4_03777 BL14DL4_03777 3634960 3636396 - Spore germination protein KA Involved in the germination response to the combination of glucose%2C fructose%2C L-asparagine%2C and KCl. Belongs to the GerABKA family gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03777 BL14DL4_03778 BL14DL4_03778 BL14DL4_03778 3636544 3637149 - Putative amino-acid transporter YisU Belongs to the LysE/ArgO transporter (TC 2. A. 75) family gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03778 BL14DL4_03779 BL14DL4_03779 BL14DL4_03779 3637281 3638720 + putative HTH-type transcriptional regulator YisV In the C-terminal sectio%3B belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03779 BL14DL4_03780 BL14DL4_03780 ectB ectB 3639007 3640353 + Diaminobutyrate--2-oxoglutarate transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL01336 diaminobutyrate-2-oxoglutarate transaminase gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03780 BL14DL4_03781 BL14DL4_03781 BL14DL4_03781 3640337 3641848 + Diaminobutyrate decarboxylase Belongs to the group II decarboxylase family%3B KEGG: bli:BL01335 L-2%2C4-diaminobutyrate decarboxylase gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03781 BL14DL4_03782 BL14DL4_03782 iucA iucA 3641845 3643611 + N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase Belongs to the IucA family%3B KEGG: vcy:IX92_17045 N2-citryl-N6-acetyl-N6-hydroxylysine synthase gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03782 BL14DL4_03783 BL14DL4_03783 iucB iucB 3643608 3644162 + N(6)-hydroxylysine O-acetyltransferase Belongs to the IucB family%3B KEGG: bba:Bd1575 acetyl CoA:N6-hydroxylysine acetyl transferase gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03783 BL14DL4_03784 BL14DL4_03784 iucD iucD 3644137 3645480 + L-lysine N(6)-monooxygenase (NADPH) Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family%3B KEGG: bpu:BPUM_1023 lysine N6-hydroxylase gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03784 BL14DL4_03785 BL14DL4_03785 iucC iucC 3645497 3647311 + Aerobactin synthase Belongs to the IucC family%3B KEGG: yin:CH53_2435 aerobactin synthase gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03785 BL14DL4_03786 BL14DL4_03786 BL14DL4_03786 3647354 3647794 - putative N-acetyltransferase YitI Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bba:Bd0335 null%3B Transferring groups other than amino-acyl groups gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03786 BL14DL4_03787 BL14DL4_03787 BL14DL4_03787 3647959 3648792 - 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: sehc:A35E_00575 3-oxoacyl-(acyl-carrier protein) reductase gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03787 BL14DL4_03788 BL14DL4_03788 BL14DL4_03788 3648904 3649866 + putative HTH-type transcriptional regulator YobV Contains 1 HTH deoR-type DNA-binding domain gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03788 BL14DL4_03789 BL14DL4_03789 metH metH 3649941 3653357 - Methionine synthase Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine%2C yielding enzyme-bound cob(I)alamin and methionine. Subsequently%2C remethylates the cofactor using methyltetrahydrofolate (By similarity)%3B Belongs to the vitamin-B12 dependent methionine synthase family%3B Contains 1 AdoMet activation domain%3B Contains 1 B12-binding domain%3B Contains 1 B12-binding N-terminal domain%3B Contains 1 Hcy-binding domain%3B Contains 1 pterin-binding domain%3B KEGG: bli:BL01308 5-methyltetrahydrofolate--homocysteine methyltransferase gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03789 BL14DL4_03790 BL14DL4_03790 BL14DL4_03790 3653350 3655179 - Homocysteine S-methyltransferase In the C-terminal sectio%3B belongs to the methylenetetrahydrofolate reductase family%3B Contains 1 Hcy-binding domain%3B KEGG: bli:BL01307 homocysteine S-methyltransferase gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03790 BL14DL4_03791 BL14DL4_03791 BL14DL4_03791 3655449 3655940 - UPF0234 protein Belongs to the UPF0234 family gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03791 BL14DL4_03792 BL14DL4_03792 BL14DL4_03792 3656104 3656952 + uncharacterized protein Contains 1 S1 motif domain gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03792 BL14DL4_03793 BL14DL4_03793 BL14DL4_03793 3656991 3657113 - hypothetical protein gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03793 BL14DL4_03794 BL14DL4_03794 BL14DL4_03794 3657268 3657474 + hypothetical protein gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03794 BL14DL4_03795 BL14DL4_03795 BL14DL4_03795 3657515 3658375 - DegV domain-containing protein YitS May bind long-chain fatty acids%2C such as palmitate%2C and may play a role in lipid transport or fatty acid metabolism%3B Contains 1 DegV domain gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03795 BL14DL4_03796 BL14DL4_03796 BL14DL4_03796 3658539 3659381 + UPF0750 membrane protein YitT Belongs to the UPF0750 family gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03796 BL14DL4_03797 BL14DL4_03797 BL14DL4_03797 3659397 3659849 + Intracellular proteinase inhibitor gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03797 BL14DL4_03798 BL14DL4_03798 guaC guaC 3659949 3660929 - GMP reductase Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase%2C nucleoside and nucleotide derivatives of G to A nucleotides%2C and in maintaining the intracellular balance of A and G nucleotides%3B Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily%3B KEGG: bsu:BSU32130 GMP reductase gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03798 BL14DL4_03799 BL14DL4_03799 BL14DL4_03799 3661106 3661294 - uncharacterized protein gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03799 BL14DL4_03800 BL14DL4_03800 BL14DL4_03800 3661533 3662345 - Putative phosphatase YitU Belongs to the HAD-like hydrolase superfamily. Cof family gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03800 BL14DL4_03801 BL14DL4_03801 BL14DL4_03801 3662468 3663235 + Esterase Displays esterase activity toward palmitoyl-CoA and pNP- butyrate gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03801 BL14DL4_03802 BL14DL4_03802 BL14DL4_03802 3663298 3663606 + MIP18 family protein YitW Belongs to the MIP18 family gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03802 BL14DL4_03803 BL14DL4_03803 argC argC 3663947 3664984 + N-acetyl-gamma-glutamyl-phosphate reductase Belongs to the NAGSA dehydrogenase family. Type 1 subfamily%3B KEGG: hhc:M911_03575 N-acetyl-gamma-glutamyl-phosphate reductase gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03803 BL14DL4_03804 BL14DL4_03804 argJ argJ 3665004 3666224 + Glutamate N-acetyltransferase Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor%2C and of ornithine by transacetylation between N(2)-acetylornithine and glutamate%3B Belongs to the ArgJ family%3B KEGG: bli:BL03242 glutamate N-acetyltransferase / amino-acid N-acetyltransferase gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03804 BL14DL4_03805 BL14DL4_03805 argB argB 3666239 3667015 + Acetylglutamate kinase Belongs to the acetylglutamate kinase family%3B KEGG: bsu:BSU11210 acetylglutamate kinase gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03805 BL14DL4_03806 BL14DL4_03806 argD argD 3667012 3668169 + Acetylornithine transaminase Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily%3B KEGG: bli:BL03244 acetylornithine aminotransferase gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03806 BL14DL4_03807 BL14DL4_03807 carA carA 3668237 3669301 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bba:Bd0856 carbamoyl-phosphate synthase small subunit gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03807 BL14DL4_03808 BL14DL4_03808 carB carB 3669294 3672383 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: dav:DESACE_04490 carbamoyl-phosphate synthase large subunit gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03808 BL14DL4_03809 BL14DL4_03809 BL14DL4_03809 3672371 3673321 + Ornithine carbamoyltransferase Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline%3B Belongs to the ATCase/OTCase family%3B KEGG: bli:BL03247 ornithine carbamoyltransferase gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03809 BL14DL4_03810 BL14DL4_03810 BL14DL4_03810 3673355 3674167 - Undecaprenyl-diphosphate phosphatase Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin%3B Belongs to the UppP family%3B KEGG: nma:NMA2077 undecaprenyl-diphosphatase gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03810 BL14DL4_03811 BL14DL4_03811 BL14DL4_03811 3674349 3674528 + uncharacterized protein gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03811 BL14DL4_03812 BL14DL4_03812 BL14DL4_03812 3674599 3674793 - putative membrane protein YjzD gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03812 BL14DL4_03813 BL14DL4_03813 BL14DL4_03813 3675025 3675759 + uncharacterized protein gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03813 BL14DL4_03814 BL14DL4_03814 BL14DL4_03814 3675846 3676421 + uncharacterized protein gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03814 BL14DL4_03815 BL14DL4_03815 BL14DL4_03815 3676508 3677461 + Transcriptional activator protein med Positive activator of the comK gene. Belongs to the BMP lipoprotein family gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03815 BL14DL4_03816 BL14DL4_03816 BL14DL4_03816 3677472 3677657 + ComG operon repressor Negatively regulates the transcription of the comG operon gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03816 BL14DL4_03817 BL14DL4_03817 BL14DL4_03817 3677709 3677948 - uncharacterized protein gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03817 BL14DL4_03818 BL14DL4_03818 BL14DL4_03818 3678118 3679056 + Beta-ketoacyl-[acyl-carrier-protein] synthase III Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for branched chain acyl-CoA%2C determining the biosynthesis of branched-chain of fatty acids instead of straight-chain%3B Belongs to the FabH family%3B KEGG: bsu:BSU11330 3-oxoacyl-(acyl-carrier-protein) synthase III gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03818 BL14DL4_03819 BL14DL4_03819 fabF fabF 3679287 3680315 + Beta-ketoacyl-[acyl-carrier-protein] synthase II Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP%3B Belongs to the beta-ketoacyl-ACP synthases family%3B KEGG: slt:Slit_0447 3-oxoacyl-(acyl-carrier-protein) synthase II gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03819 BL14DL4_03820 BL14DL4_03820 BL14DL4_03820 3680403 3681191 + uncharacterized protein gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03820 BL14DL4_03821 BL14DL4_03821 BL14DL4_03821 3681383 3682357 + Oligopeptide transport ATP-binding protein AppD This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03821 BL14DL4_03822 BL14DL4_03822 BL14DL4_03822 3682361 3683383 + Oligopeptide transport ATP-binding protein AppF This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03822 BL14DL4_03823 BL14DL4_03823 BL14DL4_03823 3683496 3685127 + Oligopeptide-binding protein AppA This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence. AppA can bind and transport tetra- and pentapeptides but not tripeptides. Belongs to the bacterial solute-binding protein 5 family gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03823 BL14DL4_03824 BL14DL4_03824 BL14DL4_03824 3685233 3686153 + Oligopeptide transport system permease protein AppB This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03824 BL14DL4_03825 BL14DL4_03825 BL14DL4_03825 3686172 3687086 + Oligopeptide transport system permease protein AppC This protein is a component of an oligopeptide permease%2C a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence%2C though%2C unlike OPP%2C is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03825 BL14DL4_03826 BL14DL4_03826 BL14DL4_03826 3687606 3688957 + Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03826 BL14DL4_03827 BL14DL4_03827 BL14DL4_03827 3688950 3689507 + Phosphopantothenoylcysteine decarboxylase Catalyzes the removal of two reducing equivalents (oxidative decarboxylation) from the cysteine residue of the C- terminal meso-lanthionine of epidermin to form a --C%3D%3DC-- double bond. Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily%3B KEGG: sul:SYO3AOP1_1251 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03827 BL14DL4_03828 BL14DL4_03828 BL14DL4_03828 3689540 3690805 + hypothetical protein gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03828 BL14DL4_03829 BL14DL4_03829 BL14DL4_03829 3691018 3691770 + UPF0736 protein Belongs to the UPF0736 family gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03829 BL14DL4_03830 BL14DL4_03830 warS warS 3692013 3693005 - Tryptophan--tRNA ligase Belongs to the class-I aminoacyl-tRNA synthetase family%3B KEGG: bex:A11Q_1236 tryptophanyl-tRNA synthetase gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03830 BL14DL4_03831 BL14DL4_03831 BL14DL4_03831 3693743 3695368 + Oligopeptide-binding protein OppA This protein is a component of the oligopeptide permease%2C a binding protein-dependent transport system%2C It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence. Belongs to the bacterial solute-binding protein 5 family gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03831 BL14DL4_03832 BL14DL4_03832 BL14DL4_03832 3695464 3696399 + Dipeptide transport system permease protein DppB Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03832 BL14DL4_03833 BL14DL4_03833 BL14DL4_03833 3696404 3697321 + Oligopeptide transport system permease protein OppC Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03833 BL14DL4_03834 BL14DL4_03834 BL14DL4_03834 3697335 3698402 + Glutathione import ATP-binding protein GsiA Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system (By similarity)%3B Belongs to the ABC transporter superfamily. Glutathione importer (TC 3. A. 1. 5. 11) family%3B Contains 2 ABC transporter domains gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03834 BL14DL4_03835 BL14DL4_03835 BL14DL4_03835 3698404 3699327 + Oligopeptide transport ATP-binding protein AmiF Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03835 BL14DL4_03836 BL14DL4_03836 BL14DL4_03836 3699558 3700136 + Putative acetyltransferase YjbC Contains 1 N-acetyltransferase domain gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03836 BL14DL4_03837 BL14DL4_03837 BL14DL4_03837 3700314 3700709 + Regulatory protein Spx Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis%2C during periods of extreme stress%3B Belongs to the ArsC family. Spx subfamily gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03837 BL14DL4_03838 BL14DL4_03838 BL14DL4_03838 3700932 3701594 - putative membrane protein YjbE Belongs to the TerC family gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03838 BL14DL4_03839 BL14DL4_03839 BL14DL4_03839 3701880 3702518 + Adapter protein MecA Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed%2C inhibits sporulation. Also involved in Spx degradation by ClpC (By similarity)%3B Belongs to the MecA family gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03839 BL14DL4_03840 BL14DL4_03840 BL14DL4_03840 3702644 3703693 + UPF0065 protein YflP Belongs to the UPF0065 (bug) family gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03840 BL14DL4_03841 BL14DL4_03841 BL14DL4_03841 3703796 3704251 + hypothetical protein gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03841 BL14DL4_03842 BL14DL4_03842 BL14DL4_03842 3704274 3705779 + putative 52.8 kDa protein in TAR-I ttuC' 3'region gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03842 BL14DL4_03843 BL14DL4_03843 BL14DL4_03843 3705799 3706515 - Transcriptional regulatory protein CitT Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon%3B Contains 1 response regulatory domain gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03843 BL14DL4_03844 BL14DL4_03844 BL14DL4_03844 3706538 3708133 - Histidine kinase Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABC%3B nuoA%3B dcu%3B dcu%3B sdhCDA%3B etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation (By similarity)%3B Contains 1 histidine kinase domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bli:BL03342 two-component system%2C CitB family%2C sensor kinase gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03844 BL14DL4_03845 BL14DL4_03845 BL14DL4_03845 3708251 3709399 + Putative competence protein CoiA Required for optimal transformation gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03845 BL14DL4_03846 BL14DL4_03846 BL14DL4_03846 3709396 3711441 + Oligoendopeptidase F like protein Belongs to the peptidase M3B family%3B KEGG: bli:BL03337 oligoendopeptidase F%3B Metalloendopeptidases gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03846 BL14DL4_03847 BL14DL4_03847 BL14DL4_03847 3711498 3711665 - putative membrane protein YizD gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03847 BL14DL4_03848 BL14DL4_03848 BL14DL4_03848 3712077 3712979 - UPF0413 protein Belongs to the UPF0413 family gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03848 BL14DL4_03849 BL14DL4_03849 BL14DL4_03849 3712976 3713374 - Group 2 truncated hemoglobin YjbI Hemoglobin-like protein that exhibits a low peroxidase activity. Its very high oxygen affinity may rule out the possibility that it is involved in oxygen transport%3B Belongs to the truncated hemoglobin family. Group II subfamily gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03849 BL14DL4_03850 BL14DL4_03850 BL14DL4_03850 3713656 3714309 - Membrane-bound lytic murein transglycosylase Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division%3B Belongs to the transglycosylase Slt family gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03850 BL14DL4_03851 BL14DL4_03851 BL14DL4_03851 3714322 3714894 - Glutathione transferase Contains 1 CYTH domain%3B KEGG: sar:SAR0971 glutathione S-transferase gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03851 BL14DL4_03852 BL14DL4_03852 BL14DL4_03852 3715025 3715390 + UPF0738 protein Belongs to the UPF0738 family gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03852 BL14DL4_03853 BL14DL4_03853 BL14DL4_03853 3715422 3716057 + GTP diphosphokinase Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a minor role in stringent response%3B Belongs to the RelA/SpoT family%3B KEGG: bli:BL03338 putative GTP pyrophosphokinase gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03853 BL14DL4_03854 BL14DL4_03854 BL14DL4_03854 3716072 3716875 + NAD(+) kinase Involved in the regulation of the intracellular balance of NAD and NADP%2C and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP%3B Belongs to the NAD kinase family%3B KEGG: bli:BL05111 NAD+ kinase gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03854 BL14DL4_03855 BL14DL4_03855 BL14DL4_03855 3716887 3717777 + 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B KEGG: bli:BL01010 23S rRNA pseudouridine1911/1915/1917 synthase gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03855 BL14DL4_03856 BL14DL4_03856 apaH apaH 3717793 3718533 - Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) Asymmetrically hydrolyzes Ap4p to yield AMP and ATP%3B Belongs to the PrpE family%3B KEGG: bli:BL05112 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03856 BL14DL4_03857 BL14DL4_03857 BL14DL4_03857 3718806 3720650 + Putative Na(+)/H(+) antiporter YjbQ Probable Na(+)/H(+) antiporter%3B Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2. A. 37) family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03857 BL14DL4_03858 BL14DL4_03858 BL14DL4_03858 3720902 3721603 + Aminopyrimidine aminohydrolase Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds%2C a reaction that is part of a thiamine salvage pathway. Thus%2C catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP). To a lesser extent%2C is also able to catalyze the hydrolytic cleavage of thiamin%3B however%2C this thiaminase activity is unlikely to be physiologically relevant. Therefore%2C is involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment%2C rather than in thiamine degradation%3B Belongs to the TenA family%3B KEGG: bsu:BSU11650 thiaminase (transcriptional activator TenA) gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03858 BL14DL4_03859 BL14DL4_03859 tenI tenI 3721578 3722189 + Thiazole tautomerase Catalyzes the irreversible aromatization of 2-((2R%2C5Z)- 2-carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate (cThz*-P) to 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate (cThz-P)%2C a step in the biosynthesis of the thiazole phosphate moiety of thiamine. Cannot use cThz* as substrate%2C indicating that the phosphate group is essential. Has no thiamine phosphate synthase activity%2C despite a high sequence similarity with ThiE%3B Belongs to the thiazole tautomerase family%3B KEGG: bsu:BSU11660 thiazole tautomerase (transcriptional regulator TenI) gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03859 BL14DL4_03860 BL14DL4_03860 thiO thiO 3722146 3723282 + Glycine oxidase Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids%2C ammonia/amine%2C and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine)%2C N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine%2C D-valine%2C D-proline and D- methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate%3B Belongs to the DAO family%3B KEGG: bli:BL01590 glycine oxidase gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03860 BL14DL4_03861 BL14DL4_03861 BL14DL4_03861 3723279 3723482 + Sulfur carrier protein ThiS Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate%3B Belongs to the sulfur carrier protein ThiS family gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03861 BL14DL4_03862 BL14DL4_03862 thiG thiG 3723489 3724256 + Thiazole synthase Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro%2C sulfur can be provided by H(2)S%3B Belongs to the ThiG family%3B KEGG: enr:H650_16535 thiazole synthase gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03862 BL14DL4_03863 BL14DL4_03863 thiF thiF 3724253 3725263 + Sulfur carrier protein ThiS adenylyltransferase Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS%3B Belongs to the HesA/MoeB/ThiF family%3B KEGG: bsu:BSU11700 sulfur carrier protein ThiS adenylyltransferase gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03863 BL14DL4_03864 BL14DL4_03864 thiD thiD 3725288 3726106 + Hydroxymethylpyrimidine kinase Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP%2C and of HMP to HMP-P. Shows no activity with pyridoxal%2C pyridoxamine or pyridoxine%3B Belongs to the ThiD family%3B KEGG: bsu:BSU11710 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03864 BL14DL4_03865 BL14DL4_03865 fabI fabI 3726263 3727039 + Enoyl-[acyl-carrier-protein] reductase (NADH) Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily%3B KEGG: bli:BL05113 enoyl-(acyl-carrier protein) reductase I gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03865 BL14DL4_03866 BL14DL4_03866 BL14DL4_03866 3727143 3727622 + Spore coat protein Has an important morphogenetic role. Involved in the assembly of at least five coat proteins%2C including CotB%2C CotG%2C CotS%2C CotSA and CotW. Required for appearance of a morphologically normal outer coat. To a large degree%2C CotO and CotH act at a late stage of coat assembly from within the outer coat to direct maturation of this structure gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03866 BL14DL4_03867 BL14DL4_03867 BL14DL4_03867 3727660 3728109 - Spore coat protein Y To B. subtilis CotZ gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03867 BL14DL4_03868 BL14DL4_03868 BL14DL4_03868 3728260 3728748 - Spore coat protein Y To B. subtilis CotZ gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03868 BL14DL4_03869 BL14DL4_03869 BL14DL4_03869 3728880 3729392 - Spore coat protein X gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03869 BL14DL4_03870 BL14DL4_03870 BL14DL4_03870 3729463 3729861 - Spore coat protein gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03870 BL14DL4_03871 BL14DL4_03871 BL14DL4_03871 3729910 3730296 - Spore coat protein gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03871 BL14DL4_03872 BL14DL4_03872 BL14DL4_03872 3730443 3730799 + Sporulation protein YjcA Involved in sporulation%3B Belongs to the UPF0713 family gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03872 BL14DL4_03873 BL14DL4_03873 BL14DL4_03873 3731086 3731295 + hypothetical protein gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03873 BL14DL4_03874 BL14DL4_03874 BL14DL4_03874 3731375 3731506 + UPF0752 sporulation protein YjcZ Belongs to the UPF0752 family gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03874 BL14DL4_03875 BL14DL4_03875 BL14DL4_03875 3731636 3731893 + Sporulation-specific transcription factor SpoVIF Transcription factor involved in spore coat assembly and spore resistance. Regulates the transcription of at least cgeA%2C cotG and cotS gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03875 BL14DL4_03876 BL14DL4_03876 BL14DL4_03876 3731932 3734214 - DNA helicase May be involved in the generation of recombinogenic substrates for the subsequent action of RecA. Belongs to the helicase family. UvrD subfamily%3B Contains 1 uvrD-like helicase ATP-binding domain%3B Contains 1 uvrD-like helicase C-terminal domain%3B KEGG: bsr:I33_1319 DNA helicase II / ATP-dependent DNA helicase PcrA gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03876 BL14DL4_03877 BL14DL4_03877 BL14DL4_03877 3734336 3734593 + uncharacterized protein gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03877 BL14DL4_03878 BL14DL4_03878 BL14DL4_03878 3734633 3735220 - Alkaline phosphatase Belongs to the DedA family%3B KEGG: oih:OB2407 alkaline phosphatase gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03878 BL14DL4_03879 BL14DL4_03879 BL14DL4_03879 3735320 3736306 - UDP-arabinose 4-epimerase Catalyzes the interconversion between UDP-glucose and UDP-galactose%3B Belongs to the NAD(P)-dependent epimerase/dehydratase family%3B KEGG: psd:DSC_08845 UDP-arabinose 4-epimerase gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03879 BL14DL4_03880 BL14DL4_03880 rfbA rfbA 3736303 3737193 - Glucose-1-phosphate thymidylyltransferase Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG)%2C i. e. a glycolipid found in the membrane%2C which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity)%3B Belongs to the UDPGP type 2 family%3B KEGG: eco:b2039 glucose-1-phosphate thymidylyltransferase gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03880 BL14DL4_03881 BL14DL4_03881 BL14DL4_03881 3737216 3737611 - putative membrane protein YngA Belongs to the GtrA family gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03881 BL14DL4_03882 BL14DL4_03882 BL14DL4_03882 3737776 3738195 - putative N-acetyltransferase YjcF Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK1121 null%3B Transferring groups other than amino-acyl groups gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03882 BL14DL4_03883 BL14DL4_03883 BL14DL4_03883 3738205 3738714 - Putative phosphoesterase Belongs to the 2H phosphoesterase superfamily. YjcG family gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03883 BL14DL4_03884 BL14DL4_03884 BL14DL4_03884 3738779 3739501 - uncharacterized protein gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03884 BL14DL4_03885 BL14DL4_03885 BL14DL4_03885 3740018 3740506 - hypothetical protein gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03885 BL14DL4_03886 BL14DL4_03886 BL14DL4_03886 3740587 3741534 - putative HTH-type transcriptional regulator YobV Contains 1 HTH deoR-type DNA-binding domain gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03886 BL14DL4_03887 BL14DL4_03887 metB metB 3741843 3742967 + Cystathionine gamma-synthase Catalyzes the formation of L-cystathionine from O- acetyl-L-homoserine and L-cysteine. Can not use O-succinyl-L- homoserine as substrate. Also exhibits O-acetylhomoserine thiolyase activity%2C catalyzing the synthesis of L-homocysteine from O-acetyl-L-homoserine and sulfide%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02660 cystathionine gamma-synthase gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03887 BL14DL4_03888 BL14DL4_03888 metC metC 3742957 3744132 + Cystathionine beta-lyase Catalyzes the transformation of cystathionine into homocysteine. Also exhibits cysteine desulfhydrase activity in vitro%2C producing sulfide from cysteine%3B Belongs to the trans-sulfuration enzymes family%3B KEGG: bli:BL02659 cystathionine beta-lyase gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03888 BL14DL4_03889 BL14DL4_03889 BL14DL4_03889 3744178 3745368 - putative membrane protein YjcL gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03889 BL14DL4_03890 BL14DL4_03890 BL14DL4_03890 3745541 3746110 + hypothetical protein gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03890 BL14DL4_03891 BL14DL4_03891 BL14DL4_03891 3746100 3746384 + hypothetical protein gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03891 BL14DL4_03892 BL14DL4_03892 BL14DL4_03892 3746532 3747856 + Penicillin-binding protein 4*%3B nonfunctional due to frameshift pseudo gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03892 BL14DL4_03893 BL14DL4_03893 BL14DL4_03893 3748225 3749211 - Arabinan endo-1%2C5-alpha-L-arabinosidase Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1%2C5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan%2C wheat arabinoxylan and p-nitrophenyl-alpha-L- arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted%3B Belongs to the glycosyl hydrolase 43 family%3B KEGG: bli:BL02653 arabinan endo-1%2C5-alpha-L-arabinosidase gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03893 BL14DL4_03894 BL14DL4_03894 BL14DL4_03894 3750090 3750162 - tRNA-Val tRNA gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03894 BL14DL4_03895 BL14DL4_03895 BL14DL4_03895 3750336 3750515 + hypothetical protein gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03895 BL14DL4_03896 BL14DL4_03896 BL14DL4_03896 3750549 3751127 + Maltose O-acetyltransferase Acetylates maltose and other sugars. Belongs to the transferase hexapeptide repeat family%3B KEGG: eco:b0459 maltose O-acetyltransferase gene gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03896 BL14DL4_03897 BL14DL4_03897 BL14DL4_03897 3751219 3751584 - hypothetical protein gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03897 BL14DL4_03898 BL14DL4_03898 BL14DL4_03898 3751714 3752604 - HTH-type transcriptional activator AllS Positive regulator essential for the expression of AllD operon. Binds to the AllD promoter (By similarity)%3B Contains 1 HTH lysR-type DNA-binding domain gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03898 BL14DL4_03899 BL14DL4_03899 cysJ cysJ 3752925 3754754 + Assimilatory sulfite reductase (NADPH) Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (Probable)%3B Contains 1 FAD-binding FR-type domain%3B Contains 1 flavodoxin-like domain%3B KEGG: bsu:BSU33440 sulfite reductase (NADPH) flavoprotein alpha-component gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03899 BL14DL4_03900 BL14DL4_03900 cysI cysI 3754782 3756500 + Assimilatory sulfite reductase (NADPH) Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate%3B Belongs to the nitrite and sulfite reductase 4Fe-4S domain family%3B KEGG: bli:BL01950 sulfite reductase (NADPH) hemoprotein beta-component gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03900 BL14DL4_03901 BL14DL4_03901 BL14DL4_03901 3756558 3757445 - putative HTH-type transcriptional regulator YoaU Contains 1 HTH lysR-type DNA-binding domain gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03901 BL14DL4_03902 BL14DL4_03902 BL14DL4_03902 3757537 3758409 + putative transporter YoaV Belongs to the EamA transporter family%3B Contains 2 EamA domains gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03902 BL14DL4_03903 BL14DL4_03903 BL14DL4_03903 3758457 3758834 + Lactoylglutathione lyase KEGG: msu:MS0597 lactoylglutathione lyase gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03903 BL14DL4_03904 BL14DL4_03904 BL14DL4_03904 3758878 3759426 - uncharacterized protein gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03904 BL14DL4_03905 BL14DL4_03905 BL14DL4_03905 3759879 3760613 + N-acetylmuramoyl-L-alanine amidase Contains 2 LysM repeats%3B KEGG: beo:BEH_04935 N-acetylmuramoyl-L-alanine amidase gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03905 BL14DL4_03906 BL14DL4_03906 BL14DL4_03906 3760669 3762093 - putative MFS-type transporter YcnB Belongs to the major facilitator superfamily. EmrB family gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03906 BL14DL4_03907 BL14DL4_03907 BL14DL4_03907 3762109 3762687 - putative HTH-type transcriptional regulator Contains 1 HTH tetR-type DNA-binding domain gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03907 BL14DL4_03908 BL14DL4_03908 BL14DL4_03908 3763064 3763477 - hypothetical protein gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03908 BL14DL4_03909 BL14DL4_03909 BL14DL4_03909 3763852 3764334 - putative antitoxin YezG Probable antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable) gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03909 BL14DL4_03910 BL14DL4_03910 BL14DL4_03910 3764338 3766287 - Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03910 BL14DL4_03911 BL14DL4_03911 BL14DL4_03911 3766254 3766385 - hypothetical protein gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03911 BL14DL4_03912 BL14DL4_03912 BL14DL4_03912 3766606 3767253 + UPF0714 protein YndL Belongs to the UPF0714 family gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03912 BL14DL4_03913 BL14DL4_03913 BL14DL4_03913 3767267 3767923 - Phage-like element PBSX protein XkdA To B. subtilis YqaB gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03913 BL14DL4_03914 BL14DL4_03914 BL14DL4_03914 3768112 3768465 - Repressor LexA Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state%3B Contains 1 HTH cro/C1-type DNA-binding domain%3B KEGG: chy:CHY_1697 repressor LexA gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03914 BL14DL4_03915 BL14DL4_03915 BL14DL4_03915 3768638 3768898 + hypothetical protein gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03915 BL14DL4_03916 BL14DL4_03916 BL14DL4_03916 3768888 3769184 + hypothetical protein gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03916 BL14DL4_03917 BL14DL4_03917 BL14DL4_03917 3769185 3770015 + Phage-like element PBSX protein XkdB To B. subtilis YqaL gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03917 BL14DL4_03918 BL14DL4_03918 BL14DL4_03918 3770065 3770715 + Phage-like element PBSX protein XkdC May function as a transcriptional antiterminator. To B. subtilis YqaM gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03918 BL14DL4_03919 BL14DL4_03919 BL14DL4_03919 3770715 3770885 + hypothetical protein gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03919 BL14DL4_03920 BL14DL4_03920 BL14DL4_03920 3770986 3771327 + Phage-like element PBSX protein XkdD gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03920 BL14DL4_03921 BL14DL4_03921 BL14DL4_03921 3771324 3771527 + Phage-like element PBSX protein XtrA To B. subtilis YqaO gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03921 BL14DL4_03922 BL14DL4_03922 BL14DL4_03922 3771648 3772151 + Positive control factor gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03922 BL14DL4_03923 BL14DL4_03923 BL14DL4_03923 3772294 3773094 + PBSX phage terminase small subunit Functions as a terminase. To B. subtilis YqaS and B. subtilis phage SPP1 terminase small subunit gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03923 BL14DL4_03924 BL14DL4_03924 BL14DL4_03924 3773091 3774389 + PBSX phage terminase large subunit Functions as a terminase. To B. subtilis YqaT and phage SPP1 terminase large subunit gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03924 BL14DL4_03925 BL14DL4_03925 BL14DL4_03925 3774393 3775907 + uncharacterized protein Belongs to the phage portal family. PBSX subfamily gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03925 BL14DL4_03926 BL14DL4_03926 BL14DL4_03926 3775915 3776763 + Phage-like element PBSX protein XkdF To B. subtilis YqbD gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03926 BL14DL4_03927 BL14DL4_03927 BL14DL4_03927 3776781 3777716 + Phage-like element PBSX protein XkdG To B. subtilis YqbE gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03927 BL14DL4_03928 BL14DL4_03928 BL14DL4_03928 3777810 3778184 + uncharacterized protein gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03928 BL14DL4_03929 BL14DL4_03929 BL14DL4_03929 3778181 3778537 + uncharacterized protein To B. subtilis XkdH gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03929 BL14DL4_03930 BL14DL4_03930 BL14DL4_03930 3778534 3779022 + Phage-like element PBSX protein XkdI To B. subtilis YqbI gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03930 BL14DL4_03931 BL14DL4_03931 BL14DL4_03931 3779035 3779475 + Phage-like element PBSX protein XkdJ To B. subtilis YqbJ gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03931 BL14DL4_03932 BL14DL4_03932 BL14DL4_03932 3779476 3779700 + uncharacterized protein gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03932 BL14DL4_03933 BL14DL4_03933 BL14DL4_03933 3779700 3781046 + uncharacterized protein Belongs to the myoviridae tail sheath protein family gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03933 BL14DL4_03934 BL14DL4_03934 BL14DL4_03934 3781048 3781491 + Phage-like element PBSX protein XkdM To B. subtilis YqbM gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03934 BL14DL4_03935 BL14DL4_03935 BL14DL4_03935 3781674 3782123 + uncharacterized protein To B. subtilis XkdN gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03935 BL14DL4_03936 BL14DL4_03936 BL14DL4_03936 3782306 3786088 + Phage-like element PBSX protein XkdO To B. subtilis YqbO gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03936 BL14DL4_03937 BL14DL4_03937 BL14DL4_03937 3786081 3786737 + Phage-like element PBSX protein XkdP Contains 1 LysM repeat gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03937 BL14DL4_03938 BL14DL4_03938 BL14DL4_03938 3786794 3787774 + Phage-like element PBSX protein XkdQ To B. subtilis YqbQ gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03938 BL14DL4_03939 BL14DL4_03939 BL14DL4_03939 3787771 3788079 + Phage-like element PBSX protein XkdR To B. subtilis YqbR gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03939 BL14DL4_03940 BL14DL4_03940 BL14DL4_03940 3788098 3788526 + Phage-like element PBSX protein XkdS To B. subtilis YqbS gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03940 BL14DL4_03941 BL14DL4_03941 BL14DL4_03941 3788519 3789562 + Phage-like element PBSX protein XkdT Belongs to the Mu gp47/PBSX XkdT family gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03941 BL14DL4_03942 BL14DL4_03942 BL14DL4_03942 3789549 3790469 + Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03942 BL14DL4_03943 BL14DL4_03943 BL14DL4_03943 3790483 3790869 + hypothetical protein gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03943 BL14DL4_03944 BL14DL4_03944 BL14DL4_03944 3790885 3792090 + Phage-like element PBSX protein XkdV To B. subtilis YqcC gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03944 BL14DL4_03945 BL14DL4_03945 BL14DL4_03945 3792128 3793159 + SPBc2 prophage-derived uncharacterized protein YomR gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03945 BL14DL4_03946 BL14DL4_03946 BL14DL4_03946 3793262 3793531 + putative 11.0 kDa protein in cwlL 5'region To B. licheniformis xpaL1 and to B. subtilis XhlA gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03946 BL14DL4_03947 BL14DL4_03947 BL14DL4_03947 3793546 3793809 + putative 9.5 kDa protein in ORF3 5'region Belongs to the SPP1 holin family gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03947 BL14DL4_03948 BL14DL4_03948 BL14DL4_03948 3793860 3794924 + N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03948 BL14DL4_03949 BL14DL4_03949 BL14DL4_03949 3795026 3795703 + HTH-type transcriptional repressor RspR Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA%3B Contains 1 HTH gntR-type DNA-binding domain gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03949 BL14DL4_03950 BL14DL4_03950 rspB rspB 3795726 3796742 + L-gulonate 5-dehydrogenase Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03803 L-gulonate 5-dehydrogenase gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03950 BL14DL4_03951 BL14DL4_03951 BL14DL4_03951 3796763 3797860 + Mannonate dehydratase Catalyzes the dehydration of D-mannonate%3B Belongs to the mannonate dehydratase family%3B KEGG: bli:BL03802 mannonate dehydratase gene gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03951 BL14DL4_03952 BL14DL4_03952 BL14DL4_03952 3797836 3798684 + putative oxidoreductase UxuB Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bli:BL03801 null%3B Oxidoreductases gene gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03952 BL14DL4_03953 BL14DL4_03953 BL14DL4_03953 3798711 3799724 + L-galactonate-5-dehydrogenase Catalyzes the oxidation of L-galactonate to D- tagaturonate. Required for growth on L-galactonate as the sole carbon source. In vitro%2C can also use L-gulonate%3B Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03800 null%3B With NAD(+) or NADP(+) as acceptor gene gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03953 BL14DL4_03954 BL14DL4_03954 BL14DL4_03954 3799777 3801048 + Hexuronate transporter Aldohexuronate transport system%3B Belongs to the major facilitator superfamily. Phthalate permease family gene gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03954 BL14DL4_03955 BL14DL4_03955 BL14DL4_03955 3801338 3801511 - Stage II sporulation protein SB Antitoxin component of a toxin-antitoxin (TA) module. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic activit%3B unlike most antitoxins it does not seem to be highly labile upon expression in E. coli%3B Belongs to the SpoIISB antitoxin family gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03955 BL14DL4_03956 BL14DL4_03956 BL14DL4_03956 3801511 3802257 - Stage II sporulation protein SA Toxic component of a toxin-antitoxin (TA) module. Its toxic activity is neutralized by cognate antitoxin SpoIISB. Expression in the absence of SpoIISB permits sporulation to stage II%2C when plasmolysis zones and holes in the peptidoglycan layer are observed%2C resulting in cell death. Lethal when synthesized during vegetative growth in the absence of SpoIISB. In E. coli both the membrane bound and soluble domain are required in cis for toxin activity%3B Belongs to the SpoIISA toxin family gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03956 BL14DL4_03957 BL14DL4_03957 BL14DL4_03957 3802368 3803366 - putative low-affinity inorganic phosphate transporter Low-affinity inorganic phosphate transport%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family. Pit subfamily gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03957 BL14DL4_03958 BL14DL4_03958 BL14DL4_03958 3803379 3803996 - UPF0111 protein YkaA Belongs to the UPF0111 family gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03958 BL14DL4_03959 BL14DL4_03959 BL14DL4_03959 3804328 3806085 + Gamma-glutamyltransferase Belongs to the gamma-glutamyltransferase family%3B KEGG: bli:BL03798 gamma-glutamyltranspeptidase / glutathione hydrolase gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03959 BL14DL4_03960 BL14DL4_03960 BL14DL4_03960 3806222 3806866 + uncharacterized protein gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03960 BL14DL4_03961 BL14DL4_03961 BL14DL4_03961 3806880 3808616 + Histidine kinase Member of the two-component regulatory system YesM/YesN. Probably activates YesN by phosphorylation%3B Contains 1 HAMP domain%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03796 two-component system%2C sensor histidine kinase YesM gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03961 BL14DL4_03962 BL14DL4_03962 BL14DL4_03962 3808616 3809785 + putative transcriptional regulatory protein YesN Member of the two-component regulatory system YesM/YesN%3B Contains 1 HTH araC/xylS-type DNA-binding domain%3B Contains 1 response regulatory domain gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03962 BL14DL4_03963 BL14DL4_03963 BL14DL4_03963 3809932 3811227 + Putative ABC transporter substrate-binding protein YesO May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls%3B Belongs to the bacterial solute-binding protein 1 family gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03963 BL14DL4_03964 BL14DL4_03964 BL14DL4_03964 3811280 3812179 + putative ABC transporter permease protein YesP Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03964 BL14DL4_03965 BL14DL4_03965 BL14DL4_03965 3812183 3813076 + putative ABC transporter permease protein YesQ Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity)%3B Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03965 BL14DL4_03966 BL14DL4_03966 BL14DL4_03966 3813094 3814128 + Unsaturated rhamnogalacturonyl hydrolase Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D- galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D- glucuronic acid at the non-reducing terminus%2C although the active pockets of YesR and UGL are very similar%3B Belongs to the glycosyl hydrolase 105 family%3B KEGG: bli:BL03791 unsaturated rhamnogalacturonyl hydrolase gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03966 BL14DL4_03967 BL14DL4_03967 BL14DL4_03967 3814176 3816458 + HTH-type transcriptional regulator YesS Probable transcription factor regulating the pathway responsible for rhamnogalacturonan depolymerization. Contains 1 HTH araC/xylS-type DNA-binding domain gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03967 BL14DL4_03968 BL14DL4_03968 BL14DL4_03968 3816472 3817188 + Rhamnogalacturonan acetylesterase RhgT May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03968 BL14DL4_03969 BL14DL4_03969 BL14DL4_03969 3817175 3817867 + uncharacterized protein gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03969 BL14DL4_03970 BL14DL4_03970 BL14DL4_03970 3817882 3818493 + uncharacterized protein gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03970 BL14DL4_03971 BL14DL4_03971 yesW yesW 3818676 3820544 + Rhamnogalacturonan endolyase Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan%2C polygalacturonic acid%2C pectic acid and pectin%3B Belongs to the polysaccharide lyase 11 family%3B KEGG: bli:BL03786 rhamnogalacturonan endolyase gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03971 BL14DL4_03972 BL14DL4_03972 BL14DL4_03972 3820565 3821034 + Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03972 BL14DL4_03973 BL14DL4_03973 BL14DL4_03973 3821075 3822193 + Rhamnogalacturonan acetylesterase RhgT May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity%2C and shows strong preference for glucose pentaacetate%2C beta-naphthylacetate%2C and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan%3B Belongs to the 'GDSL' lipolytic enzyme family gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03973 BL14DL4_03974 BL14DL4_03974 yesX yesX 3822262 3824148 + Rhamnogalacturonan exolyase Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan%2C polygalacturonic acid%2C pectic acid and pectin%3B Belongs to the polysaccharide lyase 11 family%3B KEGG: bli:BL03783 rhamnogalacturonan exolyase gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03974 BL14DL4_03975 BL14DL4_03975 BL14DL4_03975 3824293 3825285 + L-glyceraldehyde 3-phosphate reductase Catalyzes the stereospecific%2C NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). The physiological role of gpr is the detoxification of L-GAP%2C which may be formed by non- enzymatic racemization of GAP. Also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo (By similarity)%3B Belongs to the shaker potassium channel beta subunit family%3B KEGG: bli:BL03782 L-glyceraldehyde 3-phosphate reductase%3B With NAD(+) or NADP(+) as acceptor gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03975 BL14DL4_03976 BL14DL4_03976 rgaE rgaE 3825302 3825946 + Rhamnogalacturonan acetylesterase May play a role in the degradation of rhamnogalacturonan derived from plant cell walls. Probably has broad substrate specificity and may degrade several types of acetylated substrates%3B Belongs to the 'GDSL' lipolytic enzyme family%3B KEGG: adl:AURDEDRAFT_140474 rhamnogalacturonan acetylesterase gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03976 BL14DL4_03977 BL14DL4_03977 lacZ lacZ 3825943 3827940 + Beta-galactosidase May play a role in the degradation of rhamnogalacturonan derived from plant cell walls%3B Belongs to the glycosyl hydrolase 42 family%3B KEGG: bld:BLi01382 beta-galactosidase gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03977 BL14DL4_03978 BL14DL4_03978 BL14DL4_03978 3828116 3830707 + uncharacterized protein gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03978 BL14DL4_03979 BL14DL4_03979 BL14DL4_03979 3830793 3832316 + Lipoprotein LipO gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03979 BL14DL4_03980 BL14DL4_03980 BL14DL4_03980 3832358 3833311 + Protein LplB Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03980 BL14DL4_03981 BL14DL4_03981 BL14DL4_03981 3833330 3834214 + Protein LplC Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03981 BL14DL4_03982 BL14DL4_03982 BL14DL4_03982 3834252 3835580 - Serine/threonine exchanger SteT Exhibits an obligate exchange activity for serine%2C threonine and aromatic amino acids%3B Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2. A. 3. 8) family gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03982 BL14DL4_03983 BL14DL4_03983 BL14DL4_03983 3835900 3836853 + Putative ring-cleaving dioxygenase MhqA Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds%3B Belongs to the extradiol ring-cleavage dioxygenase family gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03983 BL14DL4_03984 BL14DL4_03984 BL14DL4_03984 3837246 3837608 + hypothetical protein gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03984 BL14DL4_03985 BL14DL4_03985 BL14DL4_03985 3837782 3839083 - Peptidase Do Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock%2C ethanol%2C puromycin and NaCl) resistance during active exponential growth (Probable)%3B Belongs to the peptidase S1C family%3B Contains 1 PDZ (DHR) domain%3B KEGG: blh:BaLi_c15300 serine protease Do gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03985 BL14DL4_03986 BL14DL4_03986 BL14DL4_03986 3839239 3840051 + Pyrroline-5-carboxylate reductase Belongs to the pyrroline-5-carboxylate reductase family%3B KEGG: bli:BL03773 pyrroline-5-carboxylate reductase gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03986 BL14DL4_03987 BL14DL4_03987 BL14DL4_03987 3840267 3841091 + D-aminopeptidase Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates%2C the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear. Belongs to the peptidase M55 family%3B KEGG: bsu:BSU12920 D-amino peptidase%3B Aminopeptidases gene gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03987 BL14DL4_03988 BL14DL4_03988 BL14DL4_03988 3841107 3842033 + Oligopeptide transport system permease protein OppB Part of the binding-protein-dependent transport system for oligopeptide%3B probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03988 BL14DL4_03989 BL14DL4_03989 BL14DL4_03989 3842038 3842997 + Dipeptide transport system permease protein DppC Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily%3B Contains 1 ABC transmembrane type-1 domain gene gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03989 BL14DL4_03990 BL14DL4_03990 nrtC nrtC 3843005 3844003 + Oligopeptide transport ATP-binding protein AmiF Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: azo:azo0944 nitrate/nitrite transport system ATP-binding protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03990 BL14DL4_03991 BL14DL4_03991 BL14DL4_03991 3844037 3845662 + Dipeptide-binding protein DppE Part of the binding-protein-dependent transport system for dipeptide%3B probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions%2C which also induce sporulation. Belongs to the bacterial solute-binding protein 5 family gene gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03991 BL14DL4_03992 BL14DL4_03992 ldcA ldcA 3845745 3846668 + Muramoyltetrapeptide carboxypeptidase May be involved in the degradation of peptidoglycan by catalyzing the cleavage of the terminal D-alanine residue from cytoplasmic murein peptides%3B Belongs to the peptidase S66 family%3B KEGG: bli:BL03766 muramoyltetrapeptide carboxypeptidase gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03992 BL14DL4_03993 BL14DL4_03993 catB catB 3846686 3847783 + Muconate cycloisomerase Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L- Glu and has probably a role in the metabolism of the murein peptide%2C of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of the other Ala-X dipeptides L-Ala-L-Asp%2C L-Ala-L-Leu%2C L-Ala-L-Met%2C and L-Ala- L-Ser. Is not able to epimerize other L-Ala-X dipeptides. Is also active with L-Ser-L-Glu and%2C oddly%2C L-Pro-L-Glu%2C but not with L- Glu-L-Glu%2C L-Lys-L-Glu%2C L-Lys-L-Ala%2C or D-Ala-D-Ala%3B Belongs to the mandelate racemase/muconate lactonizing enzyme family%3B KEGG: pol:Bpro_4404 muconate cycloisomerase gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03993 BL14DL4_03994 BL14DL4_03994 BL14DL4_03994 3847780 3848667 + Gamma-D-glutamyl-L-lysine endopeptidase Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides%2C releasing L-Ala-D-Glu%3B Belongs to the peptidase C40 family%3B KEGG: bco:Bcell_3074 peptidoglycan endopeptidase LytE%3B Acting on peptide bonds (peptidases) gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03994 BL14DL4_03995 BL14DL4_03995 BL14DL4_03995 3848687 3849700 + Putative oligopeptide transport ATP-binding protein YkfD Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03995 BL14DL4_03996 BL14DL4_03996 ddaH ddaH 3849794 3850681 - Dimethylargininase Belongs to the DDAH family%3B KEGG: scb:SCAB_13451 dimethylargininase gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03996 BL14DL4_03997 BL14DL4_03997 BL14DL4_03997 3850872 3851390 + Acyl-CoA hydrolase Belongs to the acyl coenzyme A hydrolase family%3B Contains 1 HotDog ACOT-type domain%3B KEGG: ban:BA_2053 acyl-CoA hydrolase gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03997 BL14DL4_03998 BL14DL4_03998 BL14DL4_03998 3851501 3852244 + UPF0702 transmembrane protein YkjA%3B nonfunctional due to frameshift pseudo gene gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03998 BL14DL4_03999 BL14DL4_03999 BL14DL4_03999 3852454 3853754 + Pectate lyase%3B nonfunctional due to frameshift pseudo gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_03999 BL14DL4_04000 BL14DL4_04000 BL14DL4_04000 3853874 3854206 + Putative DNA-binding protein YizB gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04000 BL14DL4_04001 BL14DL4_04001 BL14DL4_04001 3854211 3854960 + hypothetical protein gene gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04001 BL14DL4_04002 BL14DL4_04002 BL14DL4_04002 3855053 3855553 + hypothetical protein gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04002 BL14DL4_04003 BL14DL4_04003 BL14DL4_04003 3855558 3856079 + uncharacterized protein gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04003 BL14DL4_04004 BL14DL4_04004 BL14DL4_04004 3856289 3856618 + Multidrug resistance protein YkkC Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04004 BL14DL4_04005 BL14DL4_04005 BL14DL4_04005 3856618 3856932 + Multidrug resistance protein YkkD Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes%2C neutral and anionic antimicrobials (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. YkkC/YkkD (TC 2. A. 7. 1. 5) subfamily gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04005 BL14DL4_04006 BL14DL4_04006 purU purU 3857037 3857939 + Formyltetrahydrofolate deformylase Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)%3B Belongs to the PurU family%3B Contains 1 ACT domain%3B KEGG: bli:BL03753 formyltetrahydrofolate deformylase gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04006 BL14DL4_04007 BL14DL4_04007 BL14DL4_04007 3858278 3859375 + Glutamate 5-kinase Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate%3B Belongs to the glutamate 5-kinase family%3B Contains 1 PUA domain%3B KEGG: rma:Rmag_0413 glutamate 5-kinase gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04007 BL14DL4_04008 BL14DL4_04008 BL14DL4_04008 3859388 3860635 + Glutamate-5-semialdehyde dehydrogenase Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate%3B Belongs to the gamma-glutamyl phosphate reductase family%3B KEGG: bli:BL03751 glutamate-5-semialdehyde dehydrogenase gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04008 BL14DL4_04009 BL14DL4_04009 BL14DL4_04009 3860746 3861168 + Organic hydroperoxide resistance protein OhrA Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04009 BL14DL4_04010 BL14DL4_04010 mtaP mtaP 3861210 3861662 - S-methyl-5'-thioadenosine phosphorylase Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements%3B Contains 1 HTH marR-type DNA-binding domain%3B KEGG: tmr:Tmar_1098 5'-methylthioadenosine phosphorylase gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04010 BL14DL4_04011 BL14DL4_04011 BL14DL4_04011 3861822 3862235 + Organic hydroperoxide resistance protein OhrB Involved in organic hydroperoxide resistance%3B Belongs to the OsmC/Ohr family gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04011 BL14DL4_04012 BL14DL4_04012 BL14DL4_04012 3862307 3862972 + hypothetical protein gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04012 BL14DL4_04013 BL14DL4_04013 guaD guaD 3863002 3863472 - Guanine deaminase Catalyzes the hydrolytic deamination of guanine%2C producing xanthine and ammonia%3B Belongs to the cytidine and deoxycytidylate deaminase family%3B Contains 1 CMP/dCMP-type deaminase domain%3B KEGG: bli:BL03735 guanine deaminase gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04013 BL14DL4_04014 BL14DL4_04014 BL14DL4_04014 3863619 3864251 + Phosphoglycerate mutase (2%2C3-diphosphoglycerate-independent) Catalyzes the conversion of adenosylcobalamin 5'- phosphate to adenosylcobalamin (vitamin B12%3B involved in the assembly of the nucleotide loop of cobalamin. Also catalyzes the hydrolysis of the phospho group from alpha-ribazole 5'-phosphate to form alpha-ribazole (By similarity)%3B Belongs to the phosphoglycerate mutase family%3B KEGG: bli:BL03733 probable phosphoglycerate mutase gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04014 BL14DL4_04015 BL14DL4_04015 BL14DL4_04015 3864294 3865007 - hypothetical protein gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04015 BL14DL4_04016 BL14DL4_04016 BL14DL4_04016 3865004 3865318 - hypothetical protein gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04016 BL14DL4_04017 BL14DL4_04017 BL14DL4_04017 3865526 3867814 - 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation%3B Belongs to the vitamin-B12 independent methionine synthase family%3B KEGG: bli:BL03738 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04017 BL14DL4_04018 BL14DL4_04018 BL14DL4_04018 3868285 3869238 - Major intracellular serine protease Major intracellular protease produced by Bacillus subtilis. Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL03740 major intracellular serine protease%3B Serine endopeptidases gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04018 BL14DL4_04019 BL14DL4_04019 BL14DL4_04019 3869531 3869686 + uncharacterized protein gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04019 BL14DL4_04020 BL14DL4_04020 BL14DL4_04020 3870239 3871594 + Magnesium transporter MgtE Acts as a magnesium transporter%3B Belongs to the SLC41A transporter family%3B Contains 2 CBS domains gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04020 BL14DL4_04021 BL14DL4_04021 BL14DL4_04021 3871687 3872094 + hypothetical protein gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04021 BL14DL4_04022 BL14DL4_04022 BL14DL4_04022 3872125 3872457 - HTH-type transcriptional regulator TnrA Regulator of transcription that activates or represses many genes during nitrogen-limited growt%3B among others%2C it activates nrgAB%2C nasABCDE%2C gabP%2C and represses glnRA%3B Contains 1 HTH merR-type DNA-binding domain gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04022 BL14DL4_04023 BL14DL4_04023 BL14DL4_04023 3872650 3872805 + uncharacterized protein gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04023 BL14DL4_04024 BL14DL4_04024 BL14DL4_04024 3872912 3873091 + Stress response protein YkoL gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04024 BL14DL4_04025 BL14DL4_04025 BL14DL4_04025 3873033 3873128 + hypothetical protein gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04025 BL14DL4_04026 BL14DL4_04026 BL14DL4_04026 3873265 3873726 + putative HTH-type transcriptional regulator YkoM Contains 1 HTH marR-type DNA-binding domain gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04026 BL14DL4_04027 BL14DL4_04027 BL14DL4_04027 3873732 3875582 - DNA ligase (ATP) Probably involved in DNA repair during spore germination%3B The preference of the polymerase domain for rNTPs over dNTPs may be advantageous in dormant cells%2C where the dNTP pool may be limiting%3B In the N-terminal sectio%3B belongs to the LigD polymerase family%3B In the C-terminal sectio%3B belongs to the ATP- dependent DNA ligase family gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04027 BL14DL4_04028 BL14DL4_04028 BL14DL4_04028 3875586 3876458 - Non-like proteinous end joining protein Ku Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (By similarity). Probably involved in DNA repair during spore germination%3B Belongs to the prokaryotic Ku family%3B Contains 1 Ku domain gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04028 BL14DL4_04029 BL14DL4_04029 BL14DL4_04029 3876612 3878264 - putative signaling protein Contains 1 EAL domain%3B Contains 1 GGDEF domain%3B Contains 1 MHYT domain%3B KEGG: she:Shewmr4_0791 null%3B Phosphotransferases with a nitrogenous group as acceptor gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04029 BL14DL4_04030 BL14DL4_04030 BL14DL4_04030 3878584 3879195 + putative membrane protein YkoX Belongs to the DedA family gene gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04030 BL14DL4_04031 BL14DL4_04031 BL14DL4_04031 3879467 3880234 + putative membrane protein YkoY Belongs to the TerC family gene gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04031 BL14DL4_04032 BL14DL4_04032 BL14DL4_04032 3880527 3881282 + RNA polymerase sigma factor SigI Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor plays a role in survival at low temperatures and could be involved in heat shock stress response%2C positively regulating the expression of genes such as bcrC and mreBH during this stress%3B Belongs to the sigma-70 factor family gene gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04032 BL14DL4_04033 BL14DL4_04033 BL14DL4_04033 3881279 3882370 + Peroxiredoxin Anti-sigma factor for SigI. Negatively regulates SigI activity through direct interaction%3B KEGG: smp:SMAC_05546 peroxiredoxin Q/BCP gene gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04033 BL14DL4_04034 BL14DL4_04034 BL14DL4_04034 3882383 3882580 - Small%2C acid-soluble spore protein C3 SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. Belongs to the alpha/beta-type SASP family gene gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04034 BL14DL4_04035 BL14DL4_04035 BL14DL4_04035 3882711 3883430 - uncharacterized protein gene gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04035 BL14DL4_04036 BL14DL4_04036 htpX htpX 3883572 3884465 + Protease HtpX like protein Belongs to the peptidase M48B family%3B KEGG: bsu:BSU13490 heat shock protein HtpX%3B Metalloendopeptidases gene gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04036 BL14DL4_04037 BL14DL4_04037 BL14DL4_04037 3884612 3885961 + Potassium/sodium uptake protein NtpJ Mediates electrogenic transport of potassium as well as sodium. Acts probably as a potassium-sodium cotransporter. Major sodium reentry pathway at high pH values%3B Belongs to the TrkH potassium transport family gene gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04037 BL14DL4_04038 BL14DL4_04038 BL14DL4_04038 3886074 3888074 + Penicillin-binding protein Belongs to the transpeptidase family gene gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04038 BL14DL4_04039 BL14DL4_04039 BL14DL4_04039 3888122 3888337 + uncharacterized protein gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04039 BL14DL4_04040 BL14DL4_04040 BL14DL4_04040 3888334 3888522 + uncharacterized protein gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04040 BL14DL4_04041 BL14DL4_04041 BL14DL4_04041 3888575 3889600 - Putative membrane-bound acyltransferase YkrP Belongs to the acyltransferase 3 family gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04041 BL14DL4_04042 BL14DL4_04042 kinE kinE 3889910 3892120 + Histidine kinase Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F%3B Contains 1 histidine kinase domain%3B Contains 4 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03536 two-component system%2C sporulation sensor kinase E gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04042 BL14DL4_04043 BL14DL4_04043 mgmT mgmT 3892128 3892625 + Methylated-DNA--[protein]-cysteine S-methyltransferase Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated%3B Belongs to the MGMT family%3B KEGG: bli:BL03537 methylated-DNA-(protein)-cysteine S-methyltransferase gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04043 BL14DL4_04044 BL14DL4_04044 BL14DL4_04044 3892717 3892830 + hypothetical protein gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04044 BL14DL4_04045 BL14DL4_04045 mtnA mtnA 3892837 3893898 - S-methyl-5-thioribose-1-phosphate isomerase Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)%3B Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily%3B KEGG: bli:BL03632 methylthioribose-1-phosphate isomerase gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04045 BL14DL4_04046 BL14DL4_04046 mtnK mtnK 3893904 3895100 - S-methyl-5-thioribose kinase Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate%3B Belongs to the methylthioribose kinase family%3B KEGG: bli:BL03633 5-methylthioribose kinase gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04046 BL14DL4_04047 BL14DL4_04047 BL14DL4_04047 3895412 3896191 - Hydrolase MtnU May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway%3B Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family%3B Contains 1 CN hydrolase domain gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04047 BL14DL4_04048 BL14DL4_04048 mtnE mtnE 3896287 3897477 + putative aspartate aminotransferase Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03539 aminotransferase%3B Transaminases gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04048 BL14DL4_04049 BL14DL4_04049 mtnW mtnW 3897711 3898928 + 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase Catalyzes the enolization of 2%2C3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)%3B Belongs to the RuBisCO large chain family. Type IV subfamily%3B KEGG: bsu:BSU13590 2%2C3-diketo-5-methylthiopentyl-1-phosphate enolase gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04049 BL14DL4_04050 BL14DL4_04050 mtnB mtnB 3898925 3900208 + Methylthioribulose 1-phosphate dehydratase Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2%2C3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)%3B Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1%2C2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)%3B In the N-terminal sectio%3B belongs to the HAD-like hydrolase superfamily. MtnX family%3B In the C-terminal sectio%3B belongs to the aldolase class II family. MtnB subfamily%3B KEGG: bli:BL03541 methylthioribulose-1-phosphate dehydratase gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04050 BL14DL4_04051 BL14DL4_04051 mtnD mtnD 3900229 3900768 + Acireductone dioxygenase (Ni(2+)-requiring) Catalyzes 2 different reactions between oxygene and the acireductone 1%2C2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB)%2C the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate%2C carbon monoxide and formate%2C and does not lie on the methionine recycle pathway%3B Belongs to the acireductone dioxygenase (ARD) family%3B KEGG: bsu:BSU13620 1%2C2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04051 BL14DL4_04052 BL14DL4_04052 fosB fosB 3900793 3901257 - Metallothiol transferase FosB Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor%3B Belongs to the fosfomycin resistance protein family. FosB subfamily%3B KEGG: bli:BL03635 metallothiol transferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04052 BL14DL4_04053 BL14DL4_04053 BL14DL4_04053 3901244 3901573 - putative membrane protein YkvA gene gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04053 BL14DL4_04054 BL14DL4_04054 BL14DL4_04054 3901792 3902034 + Aspartyl-phosphate phosphatase Spo0E Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation%3B Belongs to the spo0E family gene gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04054 BL14DL4_04055 BL14DL4_04055 kinD kinD 3902096 3903607 - Histidine kinase Phosphorylates the sporulation-regulatory protein spo0F and%2C to a minor extent%2C is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions%3B Contains 1 histidine kinase domain%3B KEGG: bli:BL03637 two-component system%2C sporulation sensor kinase D gene gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04055 BL14DL4_04056 BL14DL4_04056 BL14DL4_04056 3903845 3904300 + HTH-type transcriptional regulator MhqR Negatively regulates mhqA%2C mhqED%2C mhqNOP%2C and azoR2 which may contribute to the degradation of aromatic compounds%3B Contains 1 HTH marR-type DNA-binding domain gene gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04056 BL14DL4_04057 BL14DL4_04057 BL14DL4_04057 3904325 3905104 - Motility protein MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall (By similarity)%3B Belongs to the MotB family%3B Contains 1 OmpA-like domain gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04057 BL14DL4_04058 BL14DL4_04058 BL14DL4_04058 3905097 3905900 - Motility protein MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity)%3B Belongs to the MotA family gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04058 BL14DL4_04059 BL14DL4_04059 BL14DL4_04059 3906099 3908195 - ATP-dependent Clp protease ATP-binding subunit ClpE ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP%2C degrades the global regulator CtsR after heat shock. Is also involved in disaggregation of heat-denatured proteins. Has thus a role in overall protein quality control in response to heat stress%3B Belongs to the ClpA/ClpB family. ClpE subfamily%3B Contains 1 UVR domain gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04059 BL14DL4_04060 BL14DL4_04060 BL14DL4_04060 3908425 3909459 + putative membrane protein YkvI gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04060 BL14DL4_04061 BL14DL4_04061 queC queC 3909724 3910383 + 7-cyano-7-deazaguanine synthase Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))%3B Belongs to the QueC family%3B KEGG: psh:Psest_1506 7-cyano-7-deazaguanine synthase gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04061 BL14DL4_04062 BL14DL4_04062 queD queD 3910386 3910826 + 6-pyruvoyltetrahydropterin synthase Catalyzes the conversion of 7%2C8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin (CPH4) and acetaldehyde%3B Belongs to the PTPS family. QueD subfamily%3B KEGG: bsu:BSU13730 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04062 BL14DL4_04063 BL14DL4_04063 queE queE 3910876 3911550 + 7-carboxy-7-deazaguanine synthase Catalyzes the conversion of 6-carboxy-5%2C6%2C7%2C8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG)%3B Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family%3B KEGG: ead:OV14_a0984 7-carboxy-7-deazaguanine synthase gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04063 BL14DL4_04064 BL14DL4_04064 BL14DL4_04064 3911572 3912069 + PreQ(1) synthase Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)%3B Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily%3B KEGG: bsu:BSU13750 7-cyano-7-deazaguanine reductase gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04064 BL14DL4_04065 BL14DL4_04065 BL14DL4_04065 3912742 3912867 - hypothetical protein gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04065 BL14DL4_04066 BL14DL4_04066 rapH rapH 3912857 3913138 - Response regulator aspartate phosphatase Prevents sporulation by dephosphorylating Spo0F%3B Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: blh:BaLi_c16130 response regulator aspartate phosphatase H%3B Acting on ester bonds gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04066 BL14DL4_04067 BL14DL4_04067 BL14DL4_04067 3913131 3913514 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: blh:BaLi_c16130 response regulator aspartate phosphatase H%3B Acting on ester bonds gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04067 BL14DL4_04068 BL14DL4_04068 BL14DL4_04068 3913572 3913979 - Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 6 TPR repeats%3B KEGG: bld:BLi01578 response regulator aspartate phosphatase H%3B Acting on ester bonds gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04068 BL14DL4_04069 BL14DL4_04069 mobA mobA 3914362 3915153 - Molybdenum cofactor guanylyltransferase KEGG: lmob:BN419_1252 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04069 BL14DL4_04070 BL14DL4_04070 BL14DL4_04070 3915283 3915504 - putative HTH-type transcriptional regulator YozG Contains 1 HTH cro/C1-type DNA-binding domain gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04070 BL14DL4_04071 BL14DL4_04071 BL14DL4_04071 3915515 3915997 - putative membrane protein YoaS gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04071 BL14DL4_04072 BL14DL4_04072 BL14DL4_04072 3916535 3916780 - hypothetical protein gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04072 BL14DL4_04073 BL14DL4_04073 BL14DL4_04073 3917196 3917199 - Hypothetical protein%3B nonfunctional due to frameshift pseudo gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04073 BL14DL4_04074 BL14DL4_04074 BL14DL4_04074 3918355 3918699 + hypothetical protein gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04074 BL14DL4_04075 BL14DL4_04075 BL14DL4_04075 3919049 3919903 + hypothetical protein gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04075 BL14DL4_04076 BL14DL4_04076 BL14DL4_04076 3920259 3920447 - uncharacterized protein gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04076 BL14DL4_04077 BL14DL4_04077 BL14DL4_04077 3920614 3920808 + uncharacterized protein gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04077 BL14DL4_04078 BL14DL4_04078 BL14DL4_04078 3921038 3921649 + N-acetylmuramoyl-L-alanine amidase KEGG: bsu:BSU13820 N-acetylmuramoyl-L-alanine amidase gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04078 BL14DL4_04079 BL14DL4_04079 BL14DL4_04079 3921839 3923179 + Sporulation protein YkvU gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04079 BL14DL4_04080 BL14DL4_04080 BL14DL4_04080 3923244 3923735 + Sporulation thiol-disulfide oxidoreductase Thiol-disulfide oxidoreductase with a reductive function%2C involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis%2C or in thiol/disulfide bond interchange%3B Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04080 BL14DL4_04081 BL14DL4_04081 BL14DL4_04081 3923990 3925897 + Cadmium-exporting ATPase Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is required for post-transcriptional control of comK and competence development%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IB subfamily%3B KEGG: bli:BL03560 Cd2+/Zn2+-exporting ATPase gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04081 BL14DL4_04082 BL14DL4_04082 BL14DL4_04082 3926100 3927194 + Xaa-Pro dipeptidase Belongs to the peptidase M24B family%3B KEGG: bsu:BSU13860 Xaa-Pro dipeptidase gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04082 BL14DL4_04083 BL14DL4_04083 BL14DL4_04083 3927258 3927392 - hypothetical protein gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04083 BL14DL4_04084 BL14DL4_04084 BL14DL4_04084 3927884 3928609 + hypothetical protein gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04084 BL14DL4_04085 BL14DL4_04085 BL14DL4_04085 3928834 3929805 + Catabolite control protein Transcriptional regulator involved in catabolite repression of several operons. Contains 1 HTH lacI-type DNA-binding domain gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04085 BL14DL4_04086 BL14DL4_04086 BL14DL4_04086 3929938 3930783 + Beta-glucoside operon antiterminator Mediates the positive regulation of the beta-glucoside (arb) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon (By similarity)%3B Belongs to the transcriptional antiterminator BglG family%3B Contains 2 PRD domains gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04086 BL14DL4_04087 BL14DL4_04087 gamP gamP 3931006 3933102 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. Contains 1 PTS EIIA type-1 domain%3B Contains 1 PTS EIIB type-1 domain%3B Contains 1 PTS EIIC type-1 domain%3B KEGG: bli:BL03565 PTS system%2C D-glucosamine-specific IIA component gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04087 BL14DL4_04088 BL14DL4_04088 BL14DL4_04088 3933203 3933469 + Phosphocarrier protein General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III). P-Ser-HPr interacts with the catabolite control protein A (CcpA)%2C forming a complex that binds to DNA at the catabolite response elements cre%2C operator sites preceding a large number of catabolite-regulated genes. Thus%2C P-Ser-HPr is a corepressor in carbon catabolite repression (CCR)%2C a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion%2C in which it probably interacts with several non-PTS permeases and inhibits their transport activity. Belongs to the HPr family%3B Contains 1 HPr domain gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04088 BL14DL4_04089 BL14DL4_04089 ptsI ptsI 3933469 3935187 + Phosphoenolpyruvate--protein phosphotransferase General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). Belongs to the PEP-utilizing enzyme family%3B KEGG: bsu:BSU13910 phosphotransferase system%2C enzyme I%2C PtsI gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04089 BL14DL4_04090 BL14DL4_04090 BL14DL4_04090 3935307 3935540 + Transcriptional regulator SplA gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04090 BL14DL4_04091 BL14DL4_04091 splB splB 3935518 3936642 + Spore photoproduct lyase Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5%2C6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines%3B Belongs to the radical SAM superfamily. SPL family%3B KEGG: blh:BaLi_c16380 spore photoproduct lyase gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04091 BL14DL4_04092 BL14DL4_04092 BL14DL4_04092 3936686 3937354 - putative N-acetyltransferase YkwB Belongs to the acetyltransferase family%3B Contains 1 N-acetyltransferase domain gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04092 BL14DL4_04093 BL14DL4_04093 BL14DL4_04093 3937468 3939435 + Methyl-accepting chemotaxis protein McpC Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment%2C transduce a signal from the outside to the inside of the cell%2C and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B. subtilis%2C they appear to cause an increase in the turnover methyl groups%2C leading to methylation of an unidentified acceptor%2C while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyltransferase and removed by a methylesterase. McpC is required for taxis to cysteine%2C proline%2C threonine%2C glycine%2C serine%2C lysine%2C valine and arginine and for aspartate%2C glutamine%2C histidine and glutamate. Primarily mediates response to positive stimulus of PTS carbohydrates. Greatly influences the duration or magnitude of the response to negative PTS carbohydrate stimulus%3B Contains 1 cache domain%3B Contains 1 HAMP domain%3B Contains 1 methyl-accepting transducer domain gene gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04093 BL14DL4_04094 BL14DL4_04094 BL14DL4_04094 3939453 3940328 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: bld:BLi01605 3-oxoacyl-(acyl-carrier protein) reductase gene gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04094 BL14DL4_04095 BL14DL4_04095 mmsB mmsB 3940342 3941214 + 3-hydroxyisobutyrate dehydrogenase Belongs to the 3-hydroxyisobutyrate dehydrogenase family%3B KEGG: bsr:I33_1574 3-hydroxyisobutyrate dehydrogenase gene gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04095 BL14DL4_04096 BL14DL4_04096 BL14DL4_04096 3941259 3942020 - uncharacterized protein Contains 1 SCP domain gene gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04096 BL14DL4_04097 BL14DL4_04097 BL14DL4_04097 3942368 3944476 + Penicillin-binding protein Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth%3B Belongs to the transpeptidase family gene gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04097 BL14DL4_04098 BL14DL4_04098 kinA kinA 3944637 3946448 + Histidine kinase Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP. Contains 1 histidine kinase domain%3B Contains 2 PAC (PAS-associated C-terminal) domains%3B Contains 3 PAS (PER-ARNT-SIM) domains%3B KEGG: bli:BL03576 two-component system%2C sporulation sensor kinase A gene gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04098 BL14DL4_04099 BL14DL4_04099 patA patA 3946480 3947649 - Putative N-acetyl-LL-diaminopimelate aminotransferase May catalyze the conversion of L-2-acetamido-6- oxopimelate to N-acetyl-LL-2%2C6-diaminopimelate%3B Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family%3B KEGG: bli:BL03647 aminotransferase%3B Transaminases gene gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04099 BL14DL4_04100 BL14DL4_04100 BL14DL4_04100 3947841 3947999 - hypothetical protein gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04100 BL14DL4_04101 BL14DL4_04101 BL14DL4_04101 3948171 3948695 + uncharacterized protein gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04101 BL14DL4_04102 BL14DL4_04102 BL14DL4_04102 3948792 3950111 + putative MFS-type transporter YxiO Belongs to the major facilitator superfamily gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04102 BL14DL4_04103 BL14DL4_04103 BL14DL4_04103 3950185 3951102 + Chemotaxis protein CheV Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis. Moreover%2C CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis%3B Contains 1 cheW-like domain%3B Contains 1 response regulatory domain gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04103 BL14DL4_04104 BL14DL4_04104 BL14DL4_04104 3951134 3951595 - uncharacterized protein gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04104 BL14DL4_04105 BL14DL4_04105 BL14DL4_04105 3951737 3953038 - dTMP kinase Belongs to the major facilitator superfamily%3B KEGG: abai:IMCC26256_11234 dTMP kinase gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04105 BL14DL4_04106 BL14DL4_04106 BL14DL4_04106 3953127 3953624 - Putative L%2CD-transpeptidase YkuD Probable enzyme that may play an important role in cell wall biology%3B Belongs to the YkuD family%3B Contains 1 LysM repeat gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04106 BL14DL4_04107 BL14DL4_04107 BL14DL4_04107 3953804 3954661 - putative metallophosphoesterase YkuE Belongs to the metallophosphoesterase superfamily gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04107 BL14DL4_04108 BL14DL4_04108 butA butA 3954807 3955571 + Cyclopentanol dehydrogenase Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol (By similarity)%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ecy:ECSE_P3-0048 meso-butanediol dehydrogenase / (S%2CS)-butanediol dehydrogenase / diacetyl reductase%3B With NAD(+) or NADP(+) as acceptor gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04108 BL14DL4_04109 BL14DL4_04109 BL14DL4_04109 3955639 3956859 + Protein-glutamate O-methyltransferase Contains 1 EAL domain%3B KEGG: mah:MEALZ_1025 two-component system%2C chemotaxis family%2C CheB/CheR fusion protein gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04109 BL14DL4_04110 BL14DL4_04110 BL14DL4_04110 3956970 3957596 + hypothetical protein gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04110 BL14DL4_04111 BL14DL4_04111 BL14DL4_04111 3958053 3958295 + uncharacterized protein gene gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04111 BL14DL4_04112 BL14DL4_04112 BL14DL4_04112 3958307 3958456 + hypothetical protein gene gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04112 BL14DL4_04113 BL14DL4_04113 BL14DL4_04113 3958514 3959032 + uncharacterized protein gene gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04113 BL14DL4_04114 BL14DL4_04114 BL14DL4_04114 3959171 3959350 + uncharacterized protein gene gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04114 BL14DL4_04115 BL14DL4_04115 BL14DL4_04115 3959531 3959974 + CBS domain-containing protein YkuL Contains 1 CBS domain gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04115 BL14DL4_04116 BL14DL4_04116 BL14DL4_04116 3960117 3960992 + putative HTH-type transcriptional regulator YkuM Contains 1 HTH lysR-type DNA-binding domain gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04116 BL14DL4_04117 BL14DL4_04117 BL14DL4_04117 3961124 3961603 + putative flavodoxin-1 Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04117 BL14DL4_04118 BL14DL4_04118 BL14DL4_04118 3961593 3962486 + uncharacterized protein gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04118 BL14DL4_04119 BL14DL4_04119 BL14DL4_04119 3962516 3962968 + putative flavodoxin-2 Low-potential electron donor to a number of redox enzymes%3B Belongs to the flavodoxin family%3B Contains 1 flavodoxin-like domain gene gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04119 BL14DL4_04120 BL14DL4_04120 dapH dapH 3963074 3963784 + Tetrahydrodipicolinate N-acetyltransferase Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate%3B Belongs to the transferase hexapeptide repeat family. DapH subfamily%3B KEGG: bsu:BSU14180 tetrahydrodipicolinate N-acetyltransferase gene gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04120 BL14DL4_04121 BL14DL4_04121 BL14DL4_04121 3963853 3964977 + N-acetyldiaminopimelate deacetylase Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate%3B Belongs to the peptidase M20A family. N- acetyldiaminopimelate deacetylase subfamily%3B KEGG: bli:BL05143 N-acetyldiaminopimelate deacetylase gene gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04121 BL14DL4_04122 BL14DL4_04122 BL14DL4_04122 3965040 3965285 + UPF0180 protein Belongs to the UPF0180 family gene gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04122 BL14DL4_04123 BL14DL4_04123 BL14DL4_04123 3965580 3966122 + Peroxiredoxin Belongs to the thioredoxin family%3B Contains 1 thioredoxin domain%3B KEGG: bfr:BF2266 peroxiredoxin (alkyl hydroperoxide reductase subunit C) gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04123 BL14DL4_04124 BL14DL4_04124 BL14DL4_04124 3966204 3966662 + Thiol-disulfide oxidoreductase YkuV Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Contains 1 thioredoxin domain gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04124 BL14DL4_04125 BL14DL4_04125 BL14DL4_04125 3967210 3967800 + Repressor rok gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04125 BL14DL4_04126 BL14DL4_04126 BL14DL4_04126 3967946 3968902 - Sporulation protein cse15 gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04126 BL14DL4_04127 BL14DL4_04127 BL14DL4_04127 3969055 3969642 + Molybdenum cofactor guanylyltransferase Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor%3B Belongs to the MobA family%3B KEGG: bli:BL00558 molybdopterin-guanine dinucleotide biosynthesis protein A gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04127 BL14DL4_04128 BL14DL4_04128 BL14DL4_04128 3969679 3970761 + Molybdopterin-synthase adenylyltransferase Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD%3B Belongs to the HesA/MoeB/ThiF family gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04128 BL14DL4_04129 BL14DL4_04129 moeA moeA 3970781 3972073 + Molybdopterin molybdotransferase Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP%3B Belongs to the MoeA family%3B KEGG: bsu:BSU14280 molybdopterin molybdotransferase gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04129 BL14DL4_04130 BL14DL4_04130 BL14DL4_04130 3972040 3972567 + putative molybdopterin-guanine dinucleotide biosynthesis adapter protein GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor%2C and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity)%3B Belongs to the MobB family gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04130 BL14DL4_04131 BL14DL4_04131 moaE moaE 3972546 3973040 + Molybdopterin synthase Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity)%3B Belongs to the MoaE family%3B KEGG: bli:BL00554 molybdopterin synthase catalytic subunit gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04131 BL14DL4_04132 BL14DL4_04132 BL14DL4_04132 3973037 3973270 + Molybdopterin synthase sulfur carrier subunit Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin%3B Belongs to the MoaD family gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04132 BL14DL4_04133 BL14DL4_04133 BL14DL4_04133 3973300 3973677 - hypothetical protein gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04133 BL14DL4_04134 BL14DL4_04134 BL14DL4_04134 3973944 3975701 + Lipid A export ATP-binding/permease protein MsbA Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation%3B Belongs to the ABC transporter superfamily. Lipid exporter (TC 3. A. 1. 106) family%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04134 BL14DL4_04135 BL14DL4_04135 BL14DL4_04135 3975714 3977534 + putative ABC transporter ATP-binding protein YknV Belongs to the ABC transporter superfamily%3B Contains 1 ABC transmembrane type-1 domain%3B Contains 1 ABC transporter domain gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04135 BL14DL4_04136 BL14DL4_04136 BL14DL4_04136 3977654 3978334 + Membrane protein YknW Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein). Has a role in the assembly of the YknXYZ complex gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04136 BL14DL4_04137 BL14DL4_04137 BL14DL4_04137 3978335 3979471 + Putative efflux system component YknX Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04137 BL14DL4_04138 BL14DL4_04138 BL14DL4_04138 3979468 3980160 + Macrolide export ATP-binding/permease protein MacB Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD)%2C which form a pore in the inner membrane%2C and an ATP-binding domain (NBD)%2C which is responsible for energy generation. Confers resistance against macrolides%3B Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3. A. 1. 122) family%3B Contains 1 ABC transporter domain%3B KEGG: efe:EFER_1027 macrolide transport system ATP-binding/permease protein%3B Acting on acid anhydrides%3B catalyzing transmembrane movement of substances gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04138 BL14DL4_04139 BL14DL4_04139 BL14DL4_04139 3980157 3981350 + putative ABC transporter permease YknZ Part of an unusual four-component transporter%2C which is required for protection against the killing factor SdpC (sporulation-delaying protein)%3B Belongs to the ABC-4 integral membrane protein family gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04139 BL14DL4_04140 BL14DL4_04140 BL14DL4_04140 3981981 3982736 + putative HTH-type transcriptional regulator FruR Contains 1 HTH deoR-type DNA-binding domain gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04140 BL14DL4_04141 BL14DL4_04141 pfkB pfkB 3982733 3983644 + 6-phosphofructokinase Belongs to the carbohydrate kinase PfkB family%3B KEGG: sty:STY3436 6-phosphofructokinase 2 gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04141 BL14DL4_04142 BL14DL4_04142 BL14DL4_04142 3983658 3985553 + Protein-N(pi)-phosphohistidine--sugar phosphotransferase The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS)%2C a major carbohydrate active -transport system%2C catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity)%3B Contains 1 PTS EIIA type-2 domain%3B Contains 1 PTS EIIB type-2 domain%3B Contains 1 PTS EIIC type-2 domain%3B KEGG: ron:TE10_11530 PTS system%2C fructose-specific IIA component gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04142 BL14DL4_04143 BL14DL4_04143 BL14DL4_04143 3985720 3986280 + Signal peptidase I Belongs to the peptidase S26 family%3B KEGG: bli:BL01607 signal peptidase I gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04143 BL14DL4_04144 BL14DL4_04144 BL14DL4_04144 3986326 3986595 - uncharacterized protein gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04144 BL14DL4_04145 BL14DL4_04145 BL14DL4_04145 3986608 3986850 - hypothetical protein gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04145 BL14DL4_04146 BL14DL4_04146 BL14DL4_04146 3987023 3988642 + Arabinose import ATP-binding protein AraG Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system%3B Belongs to the ABC transporter superfamily. Arabinose importer (TC 3. A. 1. 2. 2) family%3B Contains 2 ABC transporter domains gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04146 BL14DL4_04147 BL14DL4_04147 BL14DL4_04147 3988700 3989074 + hypothetical protein gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04147 BL14DL4_04148 BL14DL4_04148 BL14DL4_04148 3989212 3990444 - Aminopeptidase AmpS Metal-dependent exopeptidase%3B Belongs to the peptidase M29 family%3B KEGG: bsu:BSU14450 aminopeptidase%3B Aminopeptidases gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04148 BL14DL4_04149 BL14DL4_04149 BL14DL4_04149 3990535 3990666 - uncharacterized protein gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04149 BL14DL4_04150 BL14DL4_04150 BL14DL4_04150 3990740 3991747 - Protein MreBH Belongs to the FtsA/MreB family gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04150 BL14DL4_04151 BL14DL4_04151 BL14DL4_04151 3992054 3992341 + Putative transition state regulator Abh Contains 1 SpoVT-AbrB domain%3B To B. subtilis AbrB and SpoVT gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04151 BL14DL4_04152 BL14DL4_04152 kinC kinC 3992509 3993846 + Histidine kinase Phosphorylates the sporulation-regulatory protein spo0A. Contains 1 histidine kinase domain%3B Contains 1 PAC (PAS-associated C-terminal) domain%3B Contains 1 PAS (PER-ARNT-SIM) domain%3B KEGG: bsu:BSU14490 two-component system%2C sporulation sensor kinase C gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04152 BL14DL4_04153 BL14DL4_04153 BL14DL4_04153 3993911 3994573 + Ktr system potassium uptake protein Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress%3B Belongs to the KtrA potassium transport family%3B Contains 1 RCK C-terminal domain%3B Contains 1 RCK N-terminal domain gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04153 BL14DL4_04154 BL14DL4_04154 BL14DL4_04154 3994713 3996422 + Adenine deaminase Belongs to the adenine deaminase family%3B KEGG: bli:BL01613 adenine deaminase gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04154 BL14DL4_04155 BL14DL4_04155 BL14DL4_04155 3996475 3998142 - Ribonuclease J1 An RNase that has endonuclease and 5'-3' exonuclease activity%2C playing a role in both rRNA and mRNA stability and degradation. Endonuclease activity can cleave within 4 nucleotides of the 5'-end of a triphosphorylated RNA. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Preferentially cleaves ssRNA%2C possibly in AU-rich regions. The 5'- exonuclease activity acts on 5'-hydroxyl and 5'-monophosphate but not 5'-triphosphate end%3B it can digest through stem-loop structures if they are not too stable. Required for maturation of 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal subunits. Plays a role in the secondary pathway of 23S rRNA 5' end maturation. Probably also participates in processing of pre-scRNA (the precursor of the signal recognition particle RNA)%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bsu:BSU14530 ribonuclease J%3B Acting on ester bonds gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04155 BL14DL4_04156 BL14DL4_04156 BL14DL4_04156 3998147 3998356 - UPF0356 protein Belongs to the UPF0356 family gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04156 BL14DL4_04157 BL14DL4_04157 BL14DL4_04157 3998756 3999532 + Putative phosphatase YkrA Belongs to the HAD-like hydrolase superfamily. Cof family gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04157 BL14DL4_04158 BL14DL4_04158 BL14DL4_04158 3999648 4001078 + hypothetical protein gene gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04158 BL14DL4_04159 BL14DL4_04159 BL14DL4_04159 4001113 4001670 - Peptide deformylase Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Belongs to the polypeptide deformylase family%3B KEGG: bld:BLi01671 peptide deformylase gene gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04159 BL14DL4_04160 BL14DL4_04160 BL14DL4_04160 4001789 4001920 - UPF0752 membrane protein YkzV Belongs to the UPF0752 family gene gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04160 BL14DL4_04161 BL14DL4_04161 BL14DL4_04161 4002177 4002845 + putative lipoprotein YkyA gene gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04161 BL14DL4_04162 BL14DL4_04162 BL14DL4_04162 4003245 4004360 + Pyruvate dehydrogenase (acetyl-transferring) KEGG: bsu:BSU14580 pyruvate dehydrogenase E1 component alpha subunit gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04162 BL14DL4_04163 BL14DL4_04163 BL14DL4_04163 4004364 4005341 + Pyruvate dehydrogenase (acetyl-transferring) KEGG: rhd:R2APBS1_0530 pyruvate dehydrogenase E1 component beta subunit gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04163 BL14DL4_04164 BL14DL4_04164 dlaT dlaT 4005504 4006796 + Dihydrolipoyllysine-residue acetyltransferase The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1)%2C dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The B. subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity. Belongs to the 2-oxoacid dehydrogenase family%3B Contains 1 lipoyl-binding domain%3B KEGG: rbu:PG1C_10405 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04164 BL14DL4_04165 BL14DL4_04165 BL14DL4_04165 4006801 4008213 + Dihydrolipoyl dehydrogenase Catalyzes the oxidation of dihydrolipoamide to lipoamide. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family%3B KEGG: bsu:BSU14610 dihydrolipoamide dehydrogenase gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04165 BL14DL4_04166 BL14DL4_04166 BL14DL4_04166 4008244 4008402 + hypothetical protein gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04166 BL14DL4_04167 BL14DL4_04167 BL14DL4_04167 4008332 4008709 - Pal-related lipoprotein gene gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04167 BL14DL4_04168 BL14DL4_04168 BL14DL4_04168 4009085 4009204 + uncharacterized protein gene gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04168 BL14DL4_04169 BL14DL4_04169 speA speA 4009249 4010739 - Arginine decarboxylase Catalyzes the formation of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-I family%3B KEGG: bli:BL01634 arginine decarboxylase gene gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04169 BL14DL4_04170 BL14DL4_04170 BL14DL4_04170 4010977 4011252 + UPF0223 protein Belongs to the UPF0223 family gene gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04170 BL14DL4_04171 BL14DL4_04171 BL14DL4_04171 4011304 4011939 - UPF0637 protein Belongs to the UPF0637 family gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04171 BL14DL4_04172 BL14DL4_04172 BL14DL4_04172 4012184 4012372 + uncharacterized protein gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04172 BL14DL4_04173 BL14DL4_04173 impA impA 4012514 4013308 + Inositol-phosphate phosphatase Belongs to the inositol monophosphatase family%3B KEGG: bli:BL05151 myo-inositol-1(or 4)-monophosphatase gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04173 BL14DL4_04174 BL14DL4_04174 BL14DL4_04174 4013373 4013768 + uncharacterized protein Contains 1 N-acetyltransferase domain gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04174 BL14DL4_04175 BL14DL4_04175 BL14DL4_04175 4013877 4015802 + uncharacterized protein gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04175 BL14DL4_04176 BL14DL4_04176 BL14DL4_04176 4015792 4016064 + uncharacterized protein gene gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04176 BL14DL4_04177 BL14DL4_04177 BL14DL4_04177 4016065 4016580 + RNA polymerase sigma factor YlaC Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to oxidative stress resistance%3B Belongs to the sigma-70 factor family. ECF subfamily gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04177 BL14DL4_04178 BL14DL4_04178 BL14DL4_04178 4016585 4016881 + Anti-sigma-YlaC factor YlaD Anti-sigma factor for YlaC%3B Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04178 BL14DL4_04179 BL14DL4_04179 BL14DL4_04179 4016955 4017143 - uncharacterized protein gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04179 BL14DL4_04180 BL14DL4_04180 BL14DL4_04180 4017305 4019143 + GTP-binding protein TypA/BipA like protein Not know%3B probably interacts with the ribosomes in a GTP dependent manner%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TypA subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04180 BL14DL4_04181 BL14DL4_04181 BL14DL4_04181 4019201 4019521 + putative membrane protein YlaH gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04181 BL14DL4_04182 BL14DL4_04182 BL14DL4_04182 4019543 4020049 - putative HTH-type transcriptional regulator YhjH Contains 1 HTH marR-type DNA-binding domain gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04182 BL14DL4_04183 BL14DL4_04183 mhpA mhpA 4020138 4021619 - 3-(3-hydroxy-phenyl)propanoic acid hydroxylase Catalyzes hydroxylation of the anthracycline structure at position C-6 during the biosynthesis of oxytetracyline%3B Belongs to the PheA/TfdB FAD monooxygenase family%3B KEGG: mxa:MXAN_1594 3-(3-hydroxy-phenyl)propionate hydroxylase gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04183 BL14DL4_04184 BL14DL4_04184 BL14DL4_04184 4021756 4021962 - uncharacterized protein gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04184 BL14DL4_04185 BL14DL4_04185 BL14DL4_04185 4022083 4022697 - putative lipoprotein YlaJ gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04185 BL14DL4_04186 BL14DL4_04186 BL14DL4_04186 4022853 4024181 + uncharacterized protein In the C-terminal sectio%3B belongs to the PhoH family%3B Contains 1 PINc domain gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04186 BL14DL4_04187 BL14DL4_04187 BL14DL4_04187 4024325 4024807 - uncharacterized protein gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04187 BL14DL4_04188 BL14DL4_04188 BL14DL4_04188 4024926 4025855 + Glutaminase Belongs to the glutaminase family%3B KEGG: bsr:I33_1665 glutaminase gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04188 BL14DL4_04189 BL14DL4_04189 BL14DL4_04189 4025988 4026269 + UPF0358 protein Belongs to the UPF0358 family gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04189 BL14DL4_04190 BL14DL4_04190 BL14DL4_04190 4026600 4027811 + Putative lipid II flippase FtsW Essential cell division protein (Probable). Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane (By similarity)%3B Belongs to the SEDS family. FtsW subfamily gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04190 BL14DL4_04191 BL14DL4_04191 BL14DL4_04191 4027890 4031333 + Pyruvate carboxylase Catalyzes a 2-step reaction%2C involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second%2C leading to oxaloacetate production. Fulfills an anaplerotic function in B. subtilis as it is necessary for growth on glucose%2C but is not required for sporulation%3B Contains 1 ATP-grasp domain%3B Contains 1 biotin carboxylation domain%3B Contains 1 biotinyl-binding domain%3B Contains 1 carboxyltransferase domain%3B KEGG: bsu:BSU14860 pyruvate carboxylase gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04191 BL14DL4_04192 BL14DL4_04192 BL14DL4_04192 4031415 4032323 - Heme A synthase Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group%3B Belongs to the COX15/CtaA family. Type 1 subfamily gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04192 BL14DL4_04193 BL14DL4_04193 cyoE cyoE 4032725 4033651 + Protoheme IX farnesyltransferase Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group%3B Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily%3B KEGG: bli:BL02979 protoheme IX farnesyltransferase%3B Transferring alkyl or aryl groups%2C other than methyl groups gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04193 BL14DL4_04194 BL14DL4_04194 coxB coxB 4033929 4034996 + Cytochrome-c oxidase Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). Belongs to the cytochrome c oxidase subunit 2 family%3B Contains 1 cytochrome c domain%3B KEGG: bli:BL02980 cytochrome c oxidase subunit II gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04194 BL14DL4_04195 BL14DL4_04195 coxA coxA 4035029 4036897 + Cytochrome-c oxidase Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. Belongs to the heme-copper respiratory oxidase family%3B KEGG: bli:BL02981 cytochrome c oxidase subunit I gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04195 BL14DL4_04196 BL14DL4_04196 coxC coxC 4036897 4037520 + Cytochrome-c oxidase Belongs to the cytochrome c oxidase subunit 3 family%3B KEGG: bli:BL02982 cytochrome c oxidase subunit III gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04196 BL14DL4_04197 BL14DL4_04197 coxD coxD 4037523 4037852 + Cytochrome-c oxidase Belongs to the cytochrome c oxidase bacterial subunit 4 family%3B KEGG: bli:BL02983 cytochrome c oxidase subunit IV gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04197 BL14DL4_04198 BL14DL4_04198 BL14DL4_04198 4037883 4038785 + Protein CtaG gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04198 BL14DL4_04199 BL14DL4_04199 BL14DL4_04199 4038842 4039201 - uncharacterized protein gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04199 BL14DL4_04200 BL14DL4_04200 BL14DL4_04200 4039369 4039815 + uncharacterized protein Contains 2 CBS domains gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04200 BL14DL4_04201 BL14DL4_04201 BL14DL4_04201 4039956 4040999 + putative membrane protein YlbC Contains 1 SCP domain gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04201 BL14DL4_04202 BL14DL4_04202 BL14DL4_04202 4041153 4041548 + uncharacterized protein gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04202 BL14DL4_04203 BL14DL4_04203 BL14DL4_04203 4041563 4041802 + uncharacterized protein gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04203 BL14DL4_04204 BL14DL4_04204 BL14DL4_04204 4042080 4042529 + Regulatory protein YlbF Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation%2C stability or activity of ComS. May work together with YmcA to regulate community development gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04204 BL14DL4_04205 BL14DL4_04205 BL14DL4_04205 4042529 4042873 + UPF0298 protein Belongs to the UPF0298 family gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04205 BL14DL4_04206 BL14DL4_04206 BL14DL4_04206 4042983 4043117 + hypothetical protein gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04206 BL14DL4_04207 BL14DL4_04207 rsmD rsmD 4043172 4043732 + 16S rRNA (guanine(966)-N(2))-methyltransferase May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA%3B Belongs to the methyltransferase superfamily. RsmD family%3B KEGG: vsp:VS_3023 16S rRNA (guanine966-N2)-methyltransferase gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04207 BL14DL4_04208 BL14DL4_04208 coaD coaD 4043725 4044219 + Pantetheine-phosphate adenylyltransferase Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine%2C yielding dephospho-CoA (dPCoA) and pyrophosphate%3B Belongs to the bacterial CoaD family%3B KEGG: bsu:BSU15020 pantetheine-phosphate adenylyltransferase gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04208 BL14DL4_04209 BL14DL4_04209 BL14DL4_04209 4044228 4045448 - Sporulation integral membrane protein YlbJ Required for spore cortex formation gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04209 BL14DL4_04210 BL14DL4_04210 BL14DL4_04210 4045773 4046795 + uncharacterized protein Contains 1 PDZ (DHR) domain gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04210 BL14DL4_04211 BL14DL4_04211 BL14DL4_04211 4046812 4048062 - UPF0348 protein Belongs to the UPF0348 family gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04211 BL14DL4_04212 BL14DL4_04212 BL14DL4_04212 4048280 4048795 + uncharacterized protein gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04212 BL14DL4_04213 BL14DL4_04213 BL14DL4_04213 4048819 4048992 + 50S ribosomal protein L32-2 Belongs to the ribosomal protein L32P family gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04213 BL14DL4_04214 BL14DL4_04214 BL14DL4_04214 4049147 4049746 + uncharacterized protein Contains 1 HTH myb-type DNA-binding domain gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04214 BL14DL4_04215 BL14DL4_04215 BL14DL4_04215 4049789 4050268 - putative N-acetyltransferase Contains 1 N-acetyltransferase domain%3B KEGG: bcz:BCZK3680 null%3B Transferring groups other than amino-acyl groups gene gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04215 BL14DL4_04216 BL14DL4_04216 panE panE 4050451 4051332 + 2-dehydropantoate 2-reductase Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid%3B Belongs to the ketopantoate reductase family%3B KEGG: bsu:BSU15110 2-dehydropantoate 2-reductase gene gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04216 BL14DL4_04217 BL14DL4_04217 BL14DL4_04217 4051417 4053033 + Putative cysteine ligase BshC Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway%2C the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH%3B Belongs to the BshC family gene gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04217 BL14DL4_04218 BL14DL4_04218 BL14DL4_04218 4053159 4053590 + Transcriptional regulator MraZ Belongs to the MraZ family%3B Contains 2 SpoVT-AbrB domains gene gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04218 BL14DL4_04219 BL14DL4_04219 mraW mraW 4053590 4054594 + 16S rRNA (cytosine(1402)-N(4))-methyltransferase Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA%3B Belongs to the methyltransferase superfamily. RsmH family%3B KEGG: pca:Pcar_2210 16S rRNA (cytosine1402-N4)-methyltransferase gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04219 BL14DL4_04220 BL14DL4_04220 BL14DL4_04220 4054626 4054979 + Cell division protein FtsL Essential cell division protein%3B Belongs to the FtsL family gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04220 BL14DL4_04221 BL14DL4_04221 BL14DL4_04221 4054986 4057121 + Penicillin-binding protein 2B Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins%2C thereby interrupting normal cell wall synthesis. Belongs to the transpeptidase family%3B Contains 2 PASTA domains gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04221 BL14DL4_04222 BL14DL4_04222 BL14DL4_04222 4057264 4059198 + Stage V sporulation protein D Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex%2C which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell. Belongs to the transpeptidase family%3B Contains 1 PASTA domain gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04222 BL14DL4_04223 BL14DL4_04223 BL14DL4_04223 4059230 4059370 + hypothetical protein gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04223 BL14DL4_04224 BL14DL4_04224 murE murE 4059394 4060860 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan%3B Belongs to the MurCDEF family. MurE subfamily%3B KEGG: bsu:BSU15180 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-diaminopimelate ligase gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04224 BL14DL4_04225 BL14DL4_04225 mraY mraY 4060988 4061962 + Phospho-N-acetylmuramoyl-pentapeptide-transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan%3B Belongs to the glycosyltransferase 4 family. MraY subfamily%3B KEGG: bsu:BSU15190 phospho-N-acetylmuramoyl-pentapeptide-transferase gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04225 BL14DL4_04226 BL14DL4_04226 murD murD 4061963 4063318 + UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)%3B Belongs to the MurCDEF family%3B KEGG: bli:BL02241 UDP-N-acetylmuramoylalanine--D-glutamate ligase gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04226 BL14DL4_04227 BL14DL4_04227 BL14DL4_04227 4063401 4064471 + Putative lipid II flippase FtsW Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane%3B Belongs to the SEDS family. FtsW subfamily gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04227 BL14DL4_04228 BL14DL4_04228 murG murG 4064543 4065643 + Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)%3B Belongs to the glycosyltransferase 28 family. MurG subfamily%3B KEGG: gsu:GSU3069 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04228 BL14DL4_04229 BL14DL4_04229 murB murB 4065672 4066583 + UDP-N-acetylmuramate dehydrogenase Cell wall formation%3B Belongs to the MurB family%3B Contains 1 FAD-binding PCMH-type domain%3B KEGG: bsu:BSU15230 UDP-N-acetylmuramate dehydrogenase gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04229 BL14DL4_04230 BL14DL4_04230 BL14DL4_04230 4066789 4067577 + Cell division protein DivIB Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperatures%2C maybe by protecting FtsL from degradation or by promoting formation of the FtsL-DivIC complex. May modulate the transpeptidase activity of PBP-2B. Also required for efficient sporulation at all temperatures. Could be directly involved in the engulfment process or be required to form a sporulation septum competent for engulfment. Influences the Spo0J/Soj system of chromosome segregation%3B Belongs to the FtsQ/DivIB family. DivIB subfamily%3B Contains 1 POTRA domain gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04230 BL14DL4_04231 BL14DL4_04231 BL14DL4_04231 4067574 4068266 + UPF0749 protein YlxW May be involved in cell division and sporulation%3B Belongs to the UPF0749 family gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04231 BL14DL4_04232 BL14DL4_04232 BL14DL4_04232 4068292 4069017 + UPF0749 protein YlxX Belongs to the UPF0749 family gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04232 BL14DL4_04233 BL14DL4_04233 BL14DL4_04233 4069017 4069370 + Small basic protein Belongs to the sbp family gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04233 BL14DL4_04234 BL14DL4_04234 BL14DL4_04234 4069554 4070852 + Cell division protein FtsA Cell division protein that is required for the assembly of the Z ring (PubMed:16159787). May serve as a membrane anchor for the Z ring (By similarity). Binds and hydrolyzes ATP (PubMed:11298280). Also involved in sporulation (Probable)%3B Belongs to the FtsA/MreB family gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04234 BL14DL4_04235 BL14DL4_04235 BL14DL4_04235 4070887 4072020 + Cell division protein FtsZ Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity%3B Belongs to the FtsZ family gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04235 BL14DL4_04236 BL14DL4_04236 BL14DL4_04236 4072400 4073908 + Bacillopeptidase Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: blh:BaLi_c17820 bacillopeptidase F%3B Serine endopeptidases gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04236 BL14DL4_04237 BL14DL4_04237 BL14DL4_04237 4074100 4078398 + Bacillopeptidase Belongs to the peptidase S8 family%3B Contains 1 peptidase S8 domain%3B KEGG: bli:BL02253 bacillopeptidase F%3B Serine endopeptidases gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04237 BL14DL4_04238 BL14DL4_04238 BL14DL4_04238 4078500 4079510 + Sporulation sigma-E factor-processing peptidase Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity)%3B Belongs to the peptidase U4 family%3B KEGG: bli:BL02254 stage II sporulation protein GA (sporulation sigma-E factor processing peptidase)%3B Aspartic endopeptidases gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04238 BL14DL4_04239 BL14DL4_04239 BL14DL4_04239 4079570 4080289 + RNA polymerase sigma-E factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Belongs to the sigma-70 factor family gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04239 BL14DL4_04240 BL14DL4_04240 BL14DL4_04240 4080429 4081208 + RNA polymerase sigma-G factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. Belongs to the sigma-70 factor family gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04240 BL14DL4_04241 BL14DL4_04241 BL14DL4_04241 4081344 4082141 + Iron-chelate-transporting ATPase Belongs to the ABC transporter superfamily%3B Contains 1 ABC transporter domain%3B KEGG: fau:Fraau_2706 iron complex transport system ATP-binding protein gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04241 BL14DL4_04242 BL14DL4_04242 BL14DL4_04242 4082409 4083296 + 23S rRNA (guanine(745)-N(1))-methyltransferase Belongs to the methyltransferase superfamily. RlmA family%3B KEGG: blh:BaLi_c17880 23S rRNA (guanine745-N1)-methyltransferase gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04242 BL14DL4_04243 BL14DL4_04243 BL14DL4_04243 4083381 4083614 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04243 BL14DL4_04244 BL14DL4_04244 BL14DL4_04244 4083838 4084677 + Laccase domain protein YlmD Belongs to the LACC1 family gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04244 BL14DL4_04245 BL14DL4_04245 BL14DL4_04245 4084685 4085380 + UPF0001 protein YlmE Belongs to the UPF0001 family gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04245 BL14DL4_04246 BL14DL4_04246 BL14DL4_04246 4085377 4085829 + Cell division protein SepF Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation%2C perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA%3B Belongs to the SepF family gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04246 BL14DL4_04247 BL14DL4_04247 BL14DL4_04247 4085837 4086106 + putative membrane protein YlmG Belongs to the YggT family gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04247 BL14DL4_04248 BL14DL4_04248 BL14DL4_04248 4086242 4087018 + Putative RNA-binding protein YlmH Contains 1 S4 RNA-binding domain gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04248 BL14DL4_04249 BL14DL4_04249 BL14DL4_04249 4087114 4087608 + Septum site-determining protein DivIVA May act as a pilot protein%2C directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation%3B Belongs to the DivIVA family gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04249 BL14DL4_04250 BL14DL4_04250 iarS iarS 4087952 4090720 + Isoleucine--tRNA ligase Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine%2C to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)%3B Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily%3B KEGG: hhe:HH1190 isoleucyl-tRNA synthetase gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04250 BL14DL4_04251 BL14DL4_04251 BL14DL4_04251 4090981 4091346 + uncharacterized protein Contains 1 dksA C4-type zinc finger gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04251 BL14DL4_04252 BL14DL4_04252 lspA lspA 4091469 4091930 + Signal peptidase II This protein specifically catalyzes the removal of signal peptides from prolipoproteins%3B Belongs to the peptidase A8 family%3B KEGG: bsu:BSU15450 signal peptidase II gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04252 BL14DL4_04253 BL14DL4_04253 BL14DL4_04253 4091932 4092846 + 23S rRNA pseudouridine(1911/1915/1917) synthase Belongs to the pseudouridine synthase RluA family%3B Contains 1 S4 RNA-binding domain%3B KEGG: bli:BL02270 23S rRNA pseudouridine1911/1915/1917 synthase gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04253 BL14DL4_04254 BL14DL4_04254 pyrR pyrR 4093024 4093572 + Uracil phosphoribosyltransferase Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator%2C leading to a reduced expression of downstream genes%3B Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily%3B KEGG: bli:BL02271 pyrimidine operon attenuation protein / uracil phosphoribosyltransferase gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04254 BL14DL4_04255 BL14DL4_04255 BL14DL4_04255 4093775 4095079 + Uracil permease Transport of uracil in the cell. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2. A. 40) subfamily gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04255 BL14DL4_04256 BL14DL4_04256 pyrB pyrB 4095223 4096143 + Aspartate carbamoyltransferase Belongs to the ATCase/OTCase family%3B KEGG: bli:BL02273 aspartate carbamoyltransferase catalytic subunit gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04256 BL14DL4_04257 BL14DL4_04257 ura4 ura4 4096127 4097413 + Dihydroorotase Belongs to the DHOase family. Type 2 subfamily%3B KEGG: bsu:BSU15500 dihydroorotase gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04257 BL14DL4_04258 BL14DL4_04258 BL14DL4_04258 4097410 4098504 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarA family%3B Contains 1 glutamine amidotransferase type-1 domain%3B KEGG: bsu:BSU15510 carbamoyl-phosphate synthase small subunit gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04258 BL14DL4_04259 BL14DL4_04259 BL14DL4_04259 4098489 4101701 + Carbamoyl-phosphate synthase (glutamine-hydrolyzing) Belongs to the CarB family%3B Contains 2 ATP-grasp domains%3B KEGG: har:HEAR1165 carbamoyl-phosphate synthase large subunit gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04259 BL14DL4_04260 BL14DL4_04260 BL14DL4_04260 4101698 4102468 + Dihydroorotate dehydrogenase B (NAD(+))%2C electron transfer subunit Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+)%3B Belongs to the PyrK family%3B Contains 1 FAD-binding FR-type domain gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04260 BL14DL4_04261 BL14DL4_04261 BL14DL4_04261 4102465 4103403 + Dihydroorotate dehydrogenase (NAD(+)) Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor%3B Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily%3B KEGG: bld:BLi01774 dihydroorotate dehydrogenase (NAD+) catalytic subunit gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04261 BL14DL4_04262 BL14DL4_04262 pyrF pyrF 4103372 4104091 + Orotidine-5'-phosphate decarboxylase Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)%3B Belongs to the OMP decarboxylase family. Type 1 subfamily%3B KEGG: eco:b1281 orotidine-5'-phosphate decarboxylase gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04262 BL14DL4_04263 BL14DL4_04263 pyrE pyrE 4104088 4104717 + Orotate phosphoribosyltransferase Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate%2C leading to the formation of orotidine monophosphate (OMP)%3B Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily%3B KEGG: bli:BL02280 orotate phosphoribosyltransferase gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04263 BL14DL4_04264 BL14DL4_04264 BL14DL4_04264 4105063 4105206 + hypothetical protein gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04264 BL14DL4_04265 BL14DL4_04265 BL14DL4_04265 4105453 4105995 + Phosphoadenylyl-sulfate reductase (thioredoxin) Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily%3B KEGG: bsu:BSU15570 phosphoadenosine phosphosulfate reductase gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04265 BL14DL4_04266 BL14DL4_04266 BL14DL4_04266 4106007 4107071 + Sulfate permease CysP Involved in the import of sulfate%3B Belongs to the inorganic phosphate transporter (PiT) (TC 2. A. 20) family gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04266 BL14DL4_04267 BL14DL4_04267 met3 met3 4107097 4108233 + Sulfate adenylyltransferase Belongs to the sulfate adenylyltransferase family%3B KEGG: bsu:BSU15590 sulfate adenylyltransferase gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04267 BL14DL4_04268 BL14DL4_04268 cysC cysC 4108247 4108840 + Adenylyl-sulfate kinase Catalyzes the synthesis of activated sulfate%3B Belongs to the APS kinase family%3B KEGG: sun:SUN_1719 adenylylsulfate kinase gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04268 BL14DL4_04269 BL14DL4_04269 cobA cobA 4108992 4109765 + Uroporphyrinogen-III C-methyltransferase Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-%3B their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin. Belongs to the precorrin methyltransferase family%3B KEGG: shl:Shal_3534 uroporphyrin-III C-methyltransferase gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04269 BL14DL4_04270 BL14DL4_04270 sirB sirB 4109767 4110552 + Sirohydrochlorin ferrochelatase Chelates iron to the siroheme precursor%3B Belongs to the CbiX family. SirB subfamily%3B KEGG: bsu:BSU15620 sirohydrochlorin ferrochelatase gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04270 BL14DL4_04271 BL14DL4_04271 met8 met8 4110533 4111027 + Precorrin-2 dehydrogenase Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally%2C it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme%3B In the N-terminal sectio%3B belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family%3B In the C-terminal sectio%3B belongs to the precorrin methyltransferase family%3B KEGG: bli:BL02289 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04271 BL14DL4_04272 BL14DL4_04272 BL14DL4_04272 4111048 4112760 - uncharacterized protein Belongs to the NEMF family gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04272 BL14DL4_04273 BL14DL4_04273 BL14DL4_04273 4112907 4115579 + Calcium-transporting ATPase This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium%3B Belongs to the cation transport ATPase (P-type) (TC 3. A. 3) family. Type IIA subfamily%3B KEGG: bsu:BSU15650 Ca2+-transporting ATPase gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04273 BL14DL4_04274 BL14DL4_04274 BL14DL4_04274 4115681 4116565 + UPF0701 protein YloC Belongs to the UPF0701 family gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04274 BL14DL4_04275 BL14DL4_04275 BL14DL4_04275 4116641 4116910 + UPF0296 protein Belongs to the UPF0296 family gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04275 BL14DL4_04276 BL14DL4_04276 BL14DL4_04276 4116918 4117532 + Guanylate kinase Essential for recycling GMP and indirectly%2C cGMP%3B Belongs to the guanylate kinase family%3B Contains 1 guanylate kinase-like domain%3B KEGG: bsu:BSU15680 guanylate kinase gene gene4275 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04276 BL14DL4_04277 BL14DL4_04277 rpoZ rpoZ 4117535 4117735 + DNA-directed RNA polymerase Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits%3B Belongs to the RNA polymerase subunit omega family%3B KEGG: bsu:BSU15690 DNA-directed RNA polymerase subunit omega gene gene4276 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04277 BL14DL4_04278 BL14DL4_04278 BL14DL4_04278 4117817 4119034 + Phosphopantothenoylcysteine decarboxylase Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C in the latter compound is decarboxylated to form 4'-phosphopantotheine (By similarity)%3B In the N-terminal sectio%3B belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily%3B In the C-terminal sectio%3B belongs to the PPC synthetase family%3B KEGG: hpaz:K756_08760 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase gene gene4277 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04278 BL14DL4_04279 BL14DL4_04279 priA priA 4119031 4121448 + Primosomal protein N' Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex%2C via its helicase activity%2C and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA%3B Belongs to the helicase family. PriA subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bsu:BSU15710 primosomal protein N' (replication factor Y) (superfamily II helicase)%3B Acting on ATP%3B involved in cellular and subcellular movement gene gene4278 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04279 BL14DL4_04280 BL14DL4_04280 BL14DL4_04280 4121478 4121960 + Peptide deformylase Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions%3B Belongs to the polypeptide deformylase family%3B KEGG: mes:Meso_0394 peptide deformylase gene gene4279 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04280 BL14DL4_04281 BL14DL4_04281 BL14DL4_04281 4121965 4122915 + Methionyl-tRNA formyltransferase Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP%3B Belongs to the Fmt family%3B KEGG: caj:CIG1485E_1484 methionyl-tRNA formyltransferase gene gene4280 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04281 BL14DL4_04282 BL14DL4_04282 rsmB rsmB 4122899 4124251 + 16S rRNA (cytosine(967)-C(5))-methyltransferase Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family%3B KEGG: bli:BL02299 16S rRNA (cytosine967-C5)-methyltransferase gene gene4281 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04282 BL14DL4_04283 BL14DL4_04283 rlmN rlmN 4124251 4125336 + 23S rRNA (adenine(2503)-C(2))-methyltransferase Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs%3B Belongs to the radical SAM superfamily. RlmN family%3B KEGG: bli:BL02300 23S rRNA (adenine2503-C2)-methyltransferase gene gene4282 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04283 BL14DL4_04284 BL14DL4_04284 BL14DL4_04284 4125344 4126108 + Protein-serine/threonine phosphatase Protein phosphatase that dephosphorylates PrkC and FusA (elongation factor G). PrpC and prkC are cotranscribed%2C which suggests that they form a functional couple in vivo%2C PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Contains 1 PPM-type phosphatase domain%3B KEGG: bsu:BSU15760 protein phosphatase gene gene4283 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04284 BL14DL4_04285 BL14DL4_04285 BL14DL4_04285 4126102 4128075 + Non-specific serine/threonine protein kinase Protein kinase that is responsible for triggering spore germination in response to muropeptides%2C signaling bacteria to exit dormancy. Autophosphorylates and phosphorylates FusA (EF-G%2C elongation factor G%3B the latter modification is likely necessary for germination in response to peptidoglycan. PrkC is a substrate in vitro of the cotranscribed phosphatase PrpC%2C which suggests that they form a functional couple in vivo. Might also be involved in sporulation and biofilm formation. Does not seem to be involved in stress response%3B Belongs to the protein kinase superfamily. Ser/Thr protein kinase family%3B Contains 3 PASTA domains%3B Contains 1 protein kinase domain%3B KEGG: bsu:BSU15770 serine/threonine protein kinase%2C bacterial gene gene4284 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04285 BL14DL4_04286 BL14DL4_04286 BL14DL4_04286 4128088 4128972 + Putative ribosome bioproteinis GTPase RsgA May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain%3B KEGG: bli:BL02304 ribosome biogenesis GTPase%3B In phosphorus-containing anhydrides gene gene4285 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04286 BL14DL4_04287 BL14DL4_04287 BL14DL4_04287 4128976 4129632 + Ribulose-phosphate 3-epimerase Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate%3B Belongs to the ribulose-phosphate 3-epimerase family%3B KEGG: cjm:CJM1_0433 ribulose-phosphate 3-epimerase gene gene4286 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04287 BL14DL4_04288 BL14DL4_04288 thiN thiN 4129708 4130352 + Thiamine diphosphokinase Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Belongs to the thiamine pyrophosphokinase family%3B KEGG: bsu:BSU15800 thiamine pyrophosphokinase gene gene4287 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04288 BL14DL4_04289 BL14DL4_04289 BL14DL4_04289 4130623 4130811 - 50S ribosomal protein L28 Belongs to the ribosomal protein L28P family gene gene4288 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04289 BL14DL4_04290 BL14DL4_04290 BL14DL4_04290 4131099 4131461 + uncharacterized protein Belongs to the asp23 family gene gene4289 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04290 BL14DL4_04291 BL14DL4_04291 BL14DL4_04291 4131479 4133149 + uncharacterized protein Contains 1 DhaL domain gene gene4290 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04291 BL14DL4_04292 BL14DL4_04292 sdaA sdaA 4133330 4133992 + L-serine ammonia-lyase Belongs to the iron-sulfur dependent L-serine dehydratase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU15850 L-serine dehydratase gene gene4291 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04292 BL14DL4_04293 BL14DL4_04293 BL14DL4_04293 4134011 4134913 + L-serine ammonia-lyase Belongs to the iron-sulfur dependent L-serine dehydratase family%3B KEGG: bsu:BSU15860 L-serine dehydratase gene gene4292 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04293 BL14DL4_04294 BL14DL4_04294 recG recG 4134891 4136939 + DNA helicase Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) (By similarity)%3B Belongs to the helicase family. RecG subfamily%3B Contains 1 helicase ATP-binding domain%3B Contains 1 helicase C-terminal domain%3B KEGG: bli:BL02311 ATP-dependent DNA helicase RecG gene gene4293 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04294 BL14DL4_04295 BL14DL4_04295 BL14DL4_04295 4137086 4137622 + Transcription factor FapR Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism%3B Belongs to the FapR family gene gene4294 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04295 BL14DL4_04296 BL14DL4_04296 plsX plsX 4137640 4138632 + Glycerol-3-phosphate 1-O-acyltransferase Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor%2C but not acyl-CoA%3B Belongs to the PlsX family%3B KEGG: vfi:VF_1743 glycerol-3-phosphate acyltransferase PlsX gene gene4295 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04296 BL14DL4_04297 BL14DL4_04297 fabD fabD 4138650 4139609 + [Acyl-carrier-protein] S-malonyltransferase Belongs to the FabD family%3B KEGG: rah:Rahaq_2956 (acyl-carrier-protein) S-malonyltransferase gene gene4296 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04297 BL14DL4_04298 BL14DL4_04298 BL14DL4_04298 4139596 4140339 + 3-oxoacyl-[acyl-carrier-protein] reductase Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products%2C the first reductive step in the elongation cycle of fatty acid biosynthesis%3B Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: ahd:AI20_12755 3-oxoacyl-(acyl-carrier protein) reductase gene gene4297 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04298 BL14DL4_04299 BL14DL4_04299 BL14DL4_04299 4140416 4140649 + Acyl carrier protein Carrier of the growing fatty acid chain in fatty acid biosynthesis%3B Contains 1 acyl carrier domain gene gene4298 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04299 BL14DL4_04300 BL14DL4_04300 rnt1 rnt1 4140791 4141540 + Ribonuclease III Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs%2C and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism%3B Contains 1 DRBM (double-stranded RNA-binding) domain%3B Contains 1 RNase III domain%3B KEGG: bsu:BSU15930 ribonuclease III gene gene4299 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04300 BL14DL4_04301 BL14DL4_04301 BL14DL4_04301 4141640 4145200 + Chromosome partition protein Smc Required for chromosome condensation and partitioning%3B Belongs to the SMC family gene gene4300 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04301 BL14DL4_04302 BL14DL4_04302 BL14DL4_04302 4145217 4146203 + Signal recognition particle receptor FtsY Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)%3B Belongs to the GTP-binding SRP family. FtsY subfamily gene gene4301 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04302 BL14DL4_04303 BL14DL4_04303 BL14DL4_04303 4146337 4146660 + UPF0122 protein Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein%3B Belongs to the UPF0122 family gene gene4302 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04303 BL14DL4_04304 BL14DL4_04304 BL14DL4_04304 4146676 4148016 + Signal recognition particle protein Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane%2C the hydrolysis of GTP by both Ffh and FtsY%2C and the dissociation of the SRP-FtsY complex into the individual components (Probable)%3B Belongs to the GTP-binding SRP family. SRP54 subfamily gene gene4303 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04304 BL14DL4_04305 BL14DL4_04305 BL14DL4_04305 4148124 4148396 + 30S ribosomal protein S16 Belongs to the ribosomal protein S16P family gene gene4304 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04305 BL14DL4_04306 BL14DL4_04306 BL14DL4_04306 4148396 4148641 + UPF0109 protein YlqC Belongs to the UPF0109 family%3B Contains 1 KH domain gene gene4305 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04306 BL14DL4_04307 BL14DL4_04307 BL14DL4_04307 4148779 4149165 + uncharacterized protein gene gene4306 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04307 BL14DL4_04308 BL14DL4_04308 BL14DL4_04308 4149170 4149694 + Ribosome maturation factor RimM An accessory protein needed during the final step in the assembly of 30S ribosomal subunit%2C possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes%3B Belongs to the RimM family%3B Contains 1 PRC barrel domain gene gene4307 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04308 BL14DL4_04309 BL14DL4_04309 trmD trmD 4149691 4150422 + tRNA (guanine(37)-N(1))-methyltransferase Specifically methylates guanosine-37 in various tRNAs%3B Belongs to the RNA methyltransferase TrmD family%3B KEGG: dno:DNO_1009 tRNA (guanine37-N1)-methyltransferase gene gene4308 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04309 BL14DL4_04310 BL14DL4_04310 BL14DL4_04310 4150561 4150908 + 50S ribosomal protein L19 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site%3B Belongs to the ribosomal protein L19P family gene gene4309 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04310 BL14DL4_04311 BL14DL4_04311 BL14DL4_04311 4151023 4151874 + Ribosome bioproteinis GTPase Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity)%3B Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily%3B Contains 1 CP-type G (guanine nucleotide-binding) domain gene gene4310 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04311 BL14DL4_04312 BL14DL4_04312 rnhB rnhB 4151952 4152719 + Ribonuclease H Endonuclease that specifically degrades the RNA of RNA- DNA hybrids%3B Belongs to the RNase HII family%3B KEGG: bsu:BSU16060 ribonuclease HII gene gene4311 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04312 BL14DL4_04313 BL14DL4_04313 BL14DL4_04313 4152735 4154432 + uncharacterized protein gene gene4312 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04313 BL14DL4_04314 BL14DL4_04314 BL14DL4_04314 4154429 4154710 + uncharacterized protein gene gene4313 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04314 BL14DL4_04315 BL14DL4_04315 sucC sucC 4154887 4156047 + Succinate--CoA ligase (ADP-forming) Belongs to the succinate/malate CoA ligase beta subunit family%3B Contains 1 ATP-grasp domain%3B KEGG: hap:HAPS_0656 succinyl-CoA synthetase beta subunit gene gene4314 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04315 BL14DL4_04316 BL14DL4_04316 mtkB mtkB 4156066 4156968 + Malate--CoA ligase Belongs to the succinate/malate CoA ligase alpha subunit family%3B KEGG: mmt:Metme_2693 malate-CoA ligase subunit alpha gene gene4315 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04316 BL14DL4_04317 BL14DL4_04317 BL14DL4_04317 4157082 4157984 + Protein smf Belongs to the smf family gene gene4316 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04317 BL14DL4_04318 BL14DL4_04318 topA topA 4158189 4160264 + DNA topoisomerase Releases the supercoiling and torsional tension of DNA%2C which is introduced during the DNA replication and transcription%2C by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme%2C resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand%2C thus removing DNA supercoils. Finally%2C in the religation step%2C the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone%3B Belongs to the type IA topoisomerase family%3B Contains 1 Toprim domain%3B KEGG: bsu:BSU16120 DNA topoisomerase I gene gene4317 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04318 BL14DL4_04319 BL14DL4_04319 BL14DL4_04319 4160340 4161644 + Methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-methyltransferase(FADH(2)-oxidizing) Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs%3B Belongs to the MnmG family. TrmFO subfamily%3B KEGG: mor:MOC_1952 methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase gene gene4318 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04319 BL14DL4_04320 BL14DL4_04320 BL14DL4_04320 4161711 4162625 + Tyrosine recombinase XerC Site-specific tyrosine recombinase%2C which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids%3B Belongs to the 'phage' integrase family. XerC subfamily gene gene4319 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04320 BL14DL4_04321 BL14DL4_04321 hslV hslV 4162639 4163184 + HslU--HslV peptidase Protease subunit of a proteasome-like degradation complex%3B Belongs to the peptidase T1B family. HslV subfamily%3B KEGG: rhd:R2APBS1_3955 ATP-dependent HslUV protease%2C peptidase subunit HslV gene gene4320 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04321 BL14DL4_04322 BL14DL4_04322 BL14DL4_04322 4163201 4164604 + ATP-dependent protease ATPase subunit ClpY ATPase subunit of a proteasome-like degradation comple%3B this subunit has chaperone activity%3B Belongs to the ClpX chaperone family. HslU subfamily gene gene4321 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04322 BL14DL4_04323 BL14DL4_04323 BL14DL4_04323 4164643 4165422 + GTP-sensing transcriptional pleiotropic repressor CodY DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor%3B Belongs to the CodY family gene gene4322 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04323 BL14DL4_04324 BL14DL4_04324 BL14DL4_04324 4165540 4165677 - hypothetical protein gene gene4323 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04324 BL14DL4_04325 BL14DL4_04325 BL14DL4_04325 4165776 4166165 + Flagellar basal body rod protein FlgB Structural component of flagellum%2C the bacterial motility apparatus. Part of the rod structure of flagellar basal body%3B Belongs to the flagella basal body rod proteins family gene gene4324 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04325 BL14DL4_04326 BL14DL4_04326 BL14DL4_04326 4166165 4166617 + Flagellar basal-body rod protein FlgC Belongs to the flagella basal body rod proteins family gene gene4325 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04326 BL14DL4_04327 BL14DL4_04327 BL14DL4_04327 4166631 4166948 + Flagellar hook-basal body complex protein FliE Belongs to the FliE family gene gene4326 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04327 BL14DL4_04328 BL14DL4_04328 BL14DL4_04328 4166999 4168600 + Flagellar M-ring protein The M ring may be actively involved in energy transduction. Belongs to the FliF family gene gene4327 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04328 BL14DL4_04329 BL14DL4_04329 BL14DL4_04329 4168614 4169630 + Flagellar motor switch protein FliG One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliG family gene gene4328 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04329 BL14DL4_04330 BL14DL4_04330 BL14DL4_04330 4169614 4170381 + putative flagellar assembly protein FliH Needed for flagellar regrowth and assembly. Belongs to the FliH family gene gene4329 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04330 BL14DL4_04331 BL14DL4_04331 fliI fliI 4170381 4171694 + H(+)-transporting two-sector ATPase Probable catalytic subunit of a protein translocase for flagellum-specific export%2C or a proton translocase involved in local circuits at the flagellum. Belongs to the ATPase alpha/beta chains family%3B KEGG: bli:BL01269 flagellum-specific ATP synthase gene gene4330 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04331 BL14DL4_04332 BL14DL4_04332 BL14DL4_04332 4171697 4172140 + Flagellar FliJ protein Flagellar protein that affects chemotactic events%3B Belongs to the FliJ family gene gene4331 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04332 BL14DL4_04333 BL14DL4_04333 BL14DL4_04333 4172154 4172765 + FlaA locus 22.9 kDa protein gene gene4332 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04333 BL14DL4_04334 BL14DL4_04334 BL14DL4_04334 4172767 4174146 + putative flagellar hook-length control protein Controls the length of the flagellar hook%3B Belongs to the FliK family gene gene4333 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04334 BL14DL4_04335 BL14DL4_04335 BL14DL4_04335 4174146 4174613 + FlaA locus uncharacterized protein YlxG Belongs to the FlgD family gene gene4334 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04335 BL14DL4_04336 BL14DL4_04336 BL14DL4_04336 4174641 4175432 + Flagellar hook protein FlgE Belongs to the flagella basal body rod proteins family gene gene4335 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04336 BL14DL4_04337 BL14DL4_04337 BL14DL4_04337 4175687 4176118 + Flagellar protein FliL Controls the rotational direction of flagella during chemotaxis. Belongs to the FliL family gene gene4336 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04337 BL14DL4_04338 BL14DL4_04338 BL14DL4_04338 4176154 4177152 + Flagellar motor switch protein FliM One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliM family gene gene4337 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04338 BL14DL4_04339 BL14DL4_04339 BL14DL4_04339 4177142 4178275 + Flagellar motor switch phosphatase FliY Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attractant to cope with increased levels of CheY-P%3B Belongs to the FliN/MopA/SpaO family gene gene4338 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04339 BL14DL4_04340 BL14DL4_04340 BL14DL4_04340 4178302 4178664 + Chemotaxis protein CheY Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY%2C which causes counterclockwise rotation of the flagella%2C resulting in smooth swimming%3B Contains 1 response regulatory domain gene gene4339 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04340 BL14DL4_04341 BL14DL4_04341 BL14DL4_04341 4178677 4179351 + Flagellar biosynthetic protein FliZ gene gene4340 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04341 BL14DL4_04342 BL14DL4_04342 BL14DL4_04342 4179344 4180009 + Flagellar biosynthetic protein FliP Plays a role in the flagellum-specific transport system%3B Belongs to the FliP/MopC/SpaP family gene gene4341 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04342 BL14DL4_04343 BL14DL4_04343 BL14DL4_04343 4180025 4180294 + Flagellar biosynthetic protein FliQ Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family gene gene4342 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04343 BL14DL4_04344 BL14DL4_04344 BL14DL4_04344 4180302 4181078 + Flagellar biosynthetic protein FliR Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family gene gene4343 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04344 BL14DL4_04345 BL14DL4_04345 BL14DL4_04345 4181075 4182157 + Flagellar biosynthetic protein FlhB May be involved in the export of flagellum proteins. Belongs to the type III secretion exporter family gene gene4344 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04345 BL14DL4_04346 BL14DL4_04346 BL14DL4_04346 4182191 4184227 + Flagellar biosynthesis protein FlhA Involved in the export of flagellum proteins. Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family gene gene4345 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04346 BL14DL4_04347 BL14DL4_04347 BL14DL4_04347 4184224 4185336 + Flagellar biosynthesis protein FlhF Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. Belongs to the GTP-binding SRP family gene gene4346 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04347 BL14DL4_04348 BL14DL4_04348 BL14DL4_04348 4185333 4186226 + Flagellum site-determining protein YlxH Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF%3B Belongs to the ParA family gene gene4347 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04348 BL14DL4_04349 BL14DL4_04349 BL14DL4_04349 4186223 4187296 + Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon Involved in the modulation of the chemotaxis syste%3B catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR%3B Contains 1 cheB-type methylesterase domain%3B Contains 1 response regulatory domain gene gene4348 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04349 BL14DL4_04350 BL14DL4_04350 cheA cheA 4187302 4189323 + Histidine kinase Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylate%3B it can transfer its phosphate group to CheB%2C CheY or CheV%3B Contains 1 cheW-like domain%3B Contains 1 histidine kinase domain%3B Contains 1 HPt domain%3B KEGG: xcc:XCC2700 two-component system%2C chemotaxis family%2C sensor kinase CheA gene gene4349 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04350 BL14DL4_04351 BL14DL4_04351 BL14DL4_04351 4189347 4189823 + Chemotaxis protein CheW Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che%3B they are both necessary for efficient chemotaxis%3B Contains 1 cheW-like domain gene gene4350 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04351 BL14DL4_04352 BL14DL4_04352 BL14DL4_04352 4189834 4190463 + CheY-P phosphatase CheC Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6%25 as active as FliY%2C which indicates that CheC may function after addition of an attractant to cope with increased levels of CheY-P whereas FliY may function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P. In addition%2C it was shown to prevent methylation of the methyl-accepting chemotaxis proteins (MCPs). Inhibits CheD%3B Belongs to the CheC family gene gene4351 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04352 BL14DL4_04353 BL14DL4_04353 cheD cheD 4190460 4190966 + Protein-glutamine glutaminase Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase (By similarity)%3B Belongs to the CheD family%3B KEGG: bli:BL01247 chemotaxis protein CheD gene gene4352 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04353 BL14DL4_04354 BL14DL4_04354 BL14DL4_04354 4190989 4191753 + RNA polymerase sigma-D factor Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is required for the transcription of the flagellin and motility genes as well as for wild-type chemotaxis. Belongs to the sigma-70 factor family gene gene4353 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04354 BL14DL4_04355 BL14DL4_04355 BL14DL4_04355 4191848 4192360 + Swarming motility protein SwrB Required for swarming motility and for maximal sigma-D activity gene gene4354 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04355 BL14DL4_04356 BL14DL4_04356 BL14DL4_04356 4192514 4193254 + 30S ribosomal protein S2 Belongs to the ribosomal protein S2P family gene gene4355 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04356 BL14DL4_04357 BL14DL4_04357 BL14DL4_04357 4193355 4194236 + Elongation factor Ts Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA. EF- Tu. GTP complex up to the GTP hydrolysis stage on the ribosome%3B Belongs to the EF-Ts family gene gene4356 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04357 BL14DL4_04358 BL14DL4_04358 pyrH pyrH 4194386 4195108 + UMP kinase Catalyzes the reversible phosphorylation of UMP to UDP%3B Belongs to the UMP kinase family%3B KEGG: ssan:NX02_14365 uridylate kinase gene gene4357 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04358 BL14DL4_04359 BL14DL4_04359 BL14DL4_04359 4195110 4195667 + Ribosome-recycling factor Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another%3B Belongs to the RRF family gene gene4358 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04359 BL14DL4_04360 BL14DL4_04360 uppS uppS 4195797 4196579 + Ditrans%2Cpolycis-undecaprenyl-diphosphate synthase ((2E%2C6E)-farnesyl-diphosphate specific) Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids%3B Belongs to the UPP synthase family%3B KEGG: bsu:BSU16530 undecaprenyl diphosphate synthase gene gene4359 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04360 BL14DL4_04361 BL14DL4_04361 cds1 cds1 4196592 4197395 + Phosphatidate cytidylyltransferase Belongs to the CDS family%3B KEGG: bsu:BSU16540 phosphatidate cytidylyltransferase gene gene4360 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04361 BL14DL4_04362 BL14DL4_04362 BL14DL4_04362 4197442 4198593 + 1-deoxy-D-xylulose-5-phosphate reductoisomerase Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)%3B Belongs to the DXR family%3B KEGG: pat:Patl_1255 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene gene4361 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04362 BL14DL4_04363 BL14DL4_04363 rseP rseP 4198606 4199865 + putative protease eep Involved in production of the peptide pheromone cAD1. Belongs to the peptidase M50B family%3B Contains 1 PDZ (DHR) domain%3B KEGG: tcx:Tcr_1279 regulator of sigma E protease%3B Metalloendopeptidases gene gene4362 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04363 BL14DL4_04364 BL14DL4_04364 BL14DL4_04364 4199975 4201693 + Proline--tRNA ligase Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine%2C to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS%3B Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily%3B KEGG: bli:BL01235 prolyl-tRNA synthetase gene gene4363 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04364 BL14DL4_04365 BL14DL4_04365 polC polC 4201782 4206098 + DNA-directed DNA polymerase Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Belongs to the DNA polymerase type-C family. PolC subfamily%3B Contains 1 exonuclease domain%3B KEGG: bsut:BSUB_01790 DNA polymerase III subunit alpha%2C Gram-positive type gene gene4364 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04365 BL14DL4_04366 BL14DL4_04366 BL14DL4_04366 4206513 4208477 + Cellulase Belongs to the glycosyl hydrolase 9 (cellulase E) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: csc:Csac_1079 endoglucanase gene gene4365 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04366 BL14DL4_04367 BL14DL4_04367 BL14DL4_04367 4208505 4210619 + Cellulose 1%2C4-beta-cellobiosidase (non-reducing end) Belongs to the glycosyl hydrolase 48 (cellulase L) family%3B Contains 1 CBM3 (carbohydrate binding type-3) domain%3B KEGG: cth:Cthe_0071 cellulose 1%2C4-beta-cellobiosidase gene gene4366 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04367 BL14DL4_04368 BL14DL4_04368 BL14DL4_04368 4210753 4212435 + Cellulase Has endoglucanase activity on carboxymethyl-cellulose (CMC)%2C xylan and lichenan%2C but not Avicel. Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B Contains 1 dockerin domain%3B KEGG: bli:BL01230 endoglucanase gene gene4367 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04368 BL14DL4_04369 BL14DL4_04369 BL14DL4_04369 4212499 4213686 + Mannan endo-1%2C4-beta-mannosidase Endo-1%2C4-mannanase%2C a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans%3B Belongs to the glycosyl hydrolase 5 (cellulase A) family%3B KEGG: bli:BL01229 mannan endo-1%2C4-beta-mannosidase gene gene4368 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04369 BL14DL4_04370 BL14DL4_04370 BL14DL4_04370 4213880 4214353 + Ribosome maturation factor RimP Required for maturation of 30S ribosomal subunits%3B Belongs to the RimP family gene gene4369 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04370 BL14DL4_04371 BL14DL4_04371 BL14DL4_04371 4214385 4215503 + Transcription termination/antitermination protein NusA Participates in both transcription termination and antitermination%3B Belongs to the NusA family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain gene gene4370 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04371 BL14DL4_04372 BL14DL4_04372 BL14DL4_04372 4215517 4215792 + uncharacterized protein gene gene4371 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04372 BL14DL4_04373 BL14DL4_04373 BL14DL4_04373 4215793 4216095 + putative ribosomal protein YlxQ RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA%2C but also in box C/D and box C'/D' sRNAs%3B Belongs to the ribosomal protein L7Ae family gene gene4372 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04373 BL14DL4_04374 BL14DL4_04374 BL14DL4_04374 4216116 4218266 + Translation initiation factor IF-2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex%3B Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily%3B Contains 1 tr-type G (guanine nucleotide-binding) domain gene gene4373 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04374 BL14DL4_04375 BL14DL4_04375 BL14DL4_04375 4218263 4218541 + uncharacterized protein gene gene4374 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04375 BL14DL4_04376 BL14DL4_04376 BL14DL4_04376 4218560 4218913 + Ribosome-binding factor Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA%3B Belongs to the RbfA family gene gene4375 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04376 BL14DL4_04377 BL14DL4_04377 truB truB 4218985 4219914 + tRNA pseudouridine(55) synthase Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs%3B Belongs to the pseudouridine synthase TruB family. Type 1 subfamily%3B KEGG: ben:BOBLI757_107 tRNA pseudouridine55 synthase gene gene4376 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04377 BL14DL4_04378 BL14DL4_04378 ribF ribF 4219930 4220889 + Riboflavin kinase Belongs to the RibF family%3B KEGG: bsu:BSU16670 riboflavin kinase / FMN adenylyltransferase gene gene4377 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04378 BL14DL4_04379 BL14DL4_04379 BL14DL4_04379 4221075 4221344 + 30S ribosomal protein S15 One of the primary rRNA binding proteins%2C it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA%3B Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome%3B Belongs to the ribosomal protein S15P family gene gene4378 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04379 BL14DL4_04380 BL14DL4_04380 BL14DL4_04380 4221546 4223663 + Polyribonucleotide nucleotidyltransferase Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction%3B Belongs to the polyribonucleotide nucleotidyltransferase family%3B Contains 1 KH domain%3B Contains 1 S1 motif domain%3B KEGG: bmx:BMS_1508 polyribonucleotide nucleotidyltransferase gene gene4379 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04380 BL14DL4_04381 BL14DL4_04381 BL14DL4_04381 4223810 4224772 + uncharacterized protein Belongs to the polysaccharide deacetylase family%3B KEGG: baci:B1NLA3E_02370 peptidoglycan-N-acetylmuramic acid deacetylase%3B In linear amides gene gene4380 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04381 BL14DL4_04382 BL14DL4_04382 pqqL pqqL 4224809 4226038 + putative zinc protease YmxG Belongs to the peptidase M16 family%3B KEGG: ftu:FTT_1321 zinc protease%3B Metalloendopeptidases gene gene4381 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04382 BL14DL4_04383 BL14DL4_04383 BL14DL4_04383 4226124 4226384 + uncharacterized protein Belongs to the YlmC/YmxH family gene gene4382 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04383 BL14DL4_04384 BL14DL4_04384 BL14DL4_04384 4226527 4227426 + Dipicolinate synthase subunit Together with DpaB%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore gene gene4383 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04384 BL14DL4_04385 BL14DL4_04385 BL14DL4_04385 4227426 4228016 + Dipicolinate synthase subunit Together with DpaA%2C catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)%2C which constitutes up to 10%25 of the dry weight of the spore gene gene4384 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04385 BL14DL4_04386 BL14DL4_04386 BL14DL4_04386 4228143 4229183 + Aspartate-semialdehyde dehydrogenase Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate%3B Belongs to the aspartate-semialdehyde dehydrogenase family%3B KEGG: bsu:BSU16750 aspartate-semialdehyde dehydrogenase gene gene4385 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04386 BL14DL4_04387 BL14DL4_04387 BL14DL4_04387 4229274 4230488 + Aspartate kinase Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate%2C which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine%2C isoleucine and methionine%3B Belongs to the aspartokinase family%3B Contains 1 ACT domain%3B KEGG: bsu:BSU16760 aspartate kinase gene gene4386 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04387 BL14DL4_04388 BL14DL4_04388 BL14DL4_04388 4230519 4231388 + 4-hydroxy-tetrahydrodipicolinate synthase Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)%3B Belongs to the DapA family%3B KEGG: bli:BL01208 4-hydroxy-tetrahydrodipicolinate synthase gene gene4387 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04388 BL14DL4_04389 BL14DL4_04389 BL14DL4_04389 4231536 4233200 + Ribonuclease J2 Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides%2C on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation%2C despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity%3B Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily%3B KEGG: bli:BL01207 ribonuclease J%3B Acting on ester bonds gene gene4388 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04389 BL14DL4_04390 BL14DL4_04390 BL14DL4_04390 4233305 4234051 + Endopeptidase Clp Required for efficient translocation of pre-proteins across the membrane%3B Belongs to the peptidase S14 family. TepA subfamily%3B KEGG: nth:Nther_1461 ATP-dependent Clp protease%2C protease subunit gene gene4389 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04390 BL14DL4_04391 BL14DL4_04391 BL14DL4_04391 4234048 4234263 + uncharacterized protein gene gene4390 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04391 BL14DL4_04392 BL14DL4_04392 BL14DL4_04392 4234383 4236728 + DNA translocase FtsK Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site%2C which is located within the replication terminus region. Required for activation of the Xer recombinase%2C allowing activation of chromosome unlinking by recombination (By similarity)%3B Belongs to the FtsK/SpoIIIE/SftA family%3B Contains 1 FtsK domain gene gene4391 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04392 BL14DL4_04393 BL14DL4_04393 BL14DL4_04393 4236861 4237586 + putative HTH-type transcriptional regulator YmfC Contains 1 HTH gntR-type DNA-binding domain gene gene4392 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04393 BL14DL4_04394 BL14DL4_04394 BL14DL4_04394 4237722 4238927 + Bacillibactin exporter Involved in secretion of bacillibactin%3B Belongs to the major facilitator superfamily gene gene4393 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04394 BL14DL4_04395 BL14DL4_04395 BL14DL4_04395 4239069 4240349 + putative inactive metalloprotease YmfF Belongs to the peptidase M16 family%3B KEGG: tid:Thein_0626 zinc protease%3B Metalloendopeptidases gene gene4394 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04395 BL14DL4_04396 BL14DL4_04396 BL14DL4_04396 4240346 4241632 + Insulysin Belongs to the peptidase M16 family%3B KEGG: bcz:BCZK3546 insulysin gene gene4395 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04396 BL14DL4_04397 BL14DL4_04397 BL14DL4_04397 4241720 4242451 + 3-oxoacyl-[acyl-carrier-protein] reductase Belongs to the short-chain dehydrogenases/reductases (SDR) family%3B KEGG: vha:VIBHAR_02553 3-oxoacyl-(acyl-carrier protein) reductase gene gene4396 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04397 BL14DL4_04398 BL14DL4_04398 BL14DL4_04398 4242522 4242779 + uncharacterized protein gene gene4397 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04398 BL14DL4_04399 BL14DL4_04399 BL14DL4_04399 4243027 4243818 + uncharacterized protein Contains 1 ACT domain gene gene4398 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04399 BL14DL4_04400 BL14DL4_04400 BL14DL4_04400 4243836 4244738 + putative membrane protein YmfM gene gene4399 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04400 BL14DL4_04401 BL14DL4_04401 pgsA pgsA 4244805 4245386 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase This protein catalyzes the committed step to the synthesis of the acidic phospholipids%3B Belongs to the CDP-alcohol phosphatidyltransferase class-I family%3B KEGG: bsu:BSU16920 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene4400 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04401 BL14DL4_04402 BL14DL4_04402 pncC pncC 4245406 4246656 + Nicotinamide-nucleotide amidase Belongs to the CinA family%3B KEGG: bli:BL05163 nicotinamide-nucleotide amidase gene gene4401 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04402 BL14DL4_04403 BL14DL4_04403 BL14DL4_04403 4246823 4247869 + Protein RecA It interacts with LexA causing its activation and leading to its autocatalytic cleavage%3B Belongs to the RecA family gene gene4402 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04403 BL14DL4_04404 BL14DL4_04404 BL14DL4_04404 4248210 4249769 + Ribonuclease Endoribonuclease that initiates mRNA decay%3B Belongs to the RNase Y family%3B Contains 1 HD domain%3B Contains 1 KH domain%3B KEGG: bli:BL03655 ribonucrease Y%3B Acting on ester bonds gene gene4403 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04404 BL14DL4_04405 BL14DL4_04405 BL14DL4_04405 4249856 4250653 + uncharacterized protein gene gene4404 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04405 BL14DL4_04406 BL14DL4_04406 BL14DL4_04406 4250855 4251115 + Stage V sporulation protein gene gene4405 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04406 BL14DL4_04407 BL14DL4_04407 dpeP dpeP 4251220 4252140 + Membrane dipeptidase Belongs to the peptidase M19 family%3B KEGG: blh:BaLi_c19560 membrane dipeptidase gene gene4406 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04407 BL14DL4_04408 BL14DL4_04408 BL14DL4_04408 4252268 4253308 + L-threonine 3-dehydrogenase Belongs to the zinc-containing alcohol dehydrogenase family%3B KEGG: bli:BL03658 threonine 3-dehydrogenase gene gene4407 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04408 BL14DL4_04409 BL14DL4_04409 gcaT gcaT 4253324 4254499 + Glycine C-acetyltransferase Catalyzes the decarboxylative condensation of pimeloyl- [acyl-carrier protein] and L-alanine to produce 8-amino-7- oxononanoate (AON)%2C [acyl-carrier protein]%2C and carbon dioxide%3B Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily%3B KEGG: bli:BL03659 glycine C-acetyltransferase gene gene4408 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04409 BL14DL4_04410 BL14DL4_04410 miaB miaB 4254643 4256172 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A)%2C leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine%3B Belongs to the methylthiotransferase family. MiaB subfamily%3B Contains 1 MTTase N-terminal domain%3B Contains 1 TRAM domain%3B KEGG: bsu:BSU17010 tRNA-2-methylthio-N6-dimethylallyladenosine synthase gene gene4409 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04410 BL14DL4_04411 BL14DL4_04411 BL14DL4_04411 4256174 4256605 + Polar-amino-acid-transporting ATPase May work together with YlbF to regulate community development%3B KEGG: cml:BN424_2091 polar amino acid transport system ATP-binding protein gene gene4410 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04411 BL14DL4_04412 BL14DL4_04412 BL14DL4_04412 4256848 4257396 + Spore coat protein Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA%2C cotB%2C cotC%2C cotH and other genes encoding spore outer coat proteins%3B Belongs to the CotE family gene gene4411 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04412 BL14DL4_04413 BL14DL4_04413 BL14DL4_04413 4257507 4260116 + DNA mismatch repair protein MutS This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity%3B Belongs to the DNA mismatch repair MutS family gene gene4412 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04413 BL14DL4_04414 BL14DL4_04414 BL14DL4_04414 4260134 4262044 + DNA mismatch repair protein MutL This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker'%2C a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex%3B Belongs to the DNA mismatch repair MutL/HexB family gene gene4413 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04414 BL14DL4_04415 BL14DL4_04415 BL14DL4_04415 4262378 4262659 + 4-carboxymuconolactone decarboxylase Contains 1 ABM domain%3B KEGG: mme:Marme_0104 4-carboxymuconolactone decarboxylase gene gene4414 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04415 BL14DL4_04416 BL14DL4_04416 BL14DL4_04416 4262841 4263368 + Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene4415 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04416 BL14DL4_04417 BL14DL4_04417 BL14DL4_04417 4263687 4264106 + hypothetical protein gene gene4416 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04417 BL14DL4_04418 BL14DL4_04418 BL14DL4_04418 4264186 4264458 + hypothetical protein gene gene4417 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04418 BL14DL4_04419 BL14DL4_04419 BL14DL4_04419 4264610 4265596 - Putative metal chaperone YciC May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc%3B Belongs to the SIMIBI class G3E GTPase family. CobW subfamily%3B Contains 1 cobW C-terminal domain gene gene4418 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04419 BL14DL4_04420 BL14DL4_04420 nuoF nuoF 4265613 4266176 - NADH:ubiquinone reductase (H(+)-translocating) Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions%3B Belongs to the 2Fe2S Shethna-type ferredoxin family%3B KEGG: dmt:DESME_04270 NADH-quinone oxidoreductase subunit F gene gene4419 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04420 BL14DL4_04421 BL14DL4_04421 BL14DL4_04421 4266378 4266872 - Phosphinothricin acetyltransferase Plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX)%2C a rare amino acid%2C which inhibits glutamine synthetase (GlnA). Catalyzes the acetylation of L-methionine sulfoximine (MSX). It can also use L-methionine sulfone (MSO)%3B Contains 1 N-acetyltransferase domain%3B KEGG: bli:BL00151 phosphinothricin acetyltransferase gene gene4420 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04421 BL14DL4_04422 BL14DL4_04422 BL14DL4_04422 4267080 4267727 - hypothetical protein gene gene4421 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04422 BL14DL4_04423 BL14DL4_04423 BL14DL4_04423 4268001 4268111 - hypothetical protein gene gene4422 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04423 BL14DL4_04424 BL14DL4_04424 BL14DL4_04424 4268342 4269784 + Monoamine oxidase%3B nonfunctional due to frameshift pseudo gene gene4423 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04424 BL14DL4_04425 BL14DL4_04425 BL14DL4_04425 4270233 4270910 + UPF0700 transmembrane protein YoaK Belongs to the UPF0700 family gene gene4424 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04425 BL14DL4_04426 BL14DL4_04426 BL14DL4_04426 4271045 4272514 + K(+)/H(+) antiporter NhaP2 K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels%3B Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family. NhaP2 subfamily%3B Contains 1 RCK C-terminal domain gene gene4425 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04426 BL14DL4_04427 BL14DL4_04427 BL14DL4_04427 4272822 4274196 + Tetracycline resistance protein%3B nonfunctional due to frameshift pseudo gene gene4426 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04427 BL14DL4_04428 BL14DL4_04428 BL14DL4_04428 4274310 4274549 + putative hydrolase Belongs to the AB hydrolase superfamily gene gene4427 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04428 BL14DL4_04429 BL14DL4_04429 BL14DL4_04429 4274546 4275175 + putative hydrolase Belongs to the AB hydrolase superfamily gene gene4428 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04429 BL14DL4_04431 BL14DL4_04431 BL14DL4_04431 4276103 4276753 - uncharacterized protein gene gene4430 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04431 BL14DL4_04432 BL14DL4_04432 BL14DL4_04432 4276787 4277803 - Serine-type D-Ala-D-Ala carboxypeptidase Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure but its precise function is unknown%3B KEGG: msm:MSMEG_4455 D-alanyl-D-alanine carboxypeptidase gene gene4431 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04432 BL14DL4_04433 BL14DL4_04433 BL14DL4_04433 4278259 4279449 + Demethyllactenocin mycarosyltransferase Involved in the biosynthesis of mycarose which is a 6- deoxyhexose sugar required during production of the macrolide antibiotic tylosin. Catalyzes the transfer of L-mycarosyl from dTDP-beta-L-mycarose to demethyllactenocin to yield demethylmacrocin%3B Belongs to the UDP-glycosyltransferase family%3B KEGG: sma:SAV_945 dTDP-L-oleandrosyltransferase%3B Hexosyltransferases gene gene4432 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04433 BL14DL4_04434 BL14DL4_04434 BL14DL4_04434 4279575 4281152 + Aspartate-proton symporter Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency. Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2. A. 3. 11) family gene gene4433 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04434 BL14DL4_04435 BL14DL4_04435 BL14DL4_04435 4281200 4281499 - Spore coat protein F-like protein YraD Belongs to the CotF family gene gene4434 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04435 BL14DL4_04436 BL14DL4_04436 BL14DL4_04436 4281496 4281696 - uncharacterized protein gene gene4435 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04436 BL14DL4_04437 BL14DL4_04437 BL14DL4_04437 4281808 4283076 - N-acetylmuramoyl-L-alanine amidase Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily%3B Contains 2 LysM repeats%3B KEGG: mta:Moth_0054 N-acetylmuramoyl-L-alanine amidase gene gene4436 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04437 BL14DL4_04438 BL14DL4_04438 BL14DL4_04438 4283250 4283834 + putative HTH-type transcriptional regulator YezE Contains 1 HTH tetR-type DNA-binding domain gene gene4437 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04438 BL14DL4_04439 BL14DL4_04439 BL14DL4_04439 4283922 4284251 + uncharacterized protein Belongs to the limonene-1%2C2-epoxide hydrolase family gene gene4438 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04439 BL14DL4_04440 BL14DL4_04440 BL14DL4_04440 4284381 4285211 + NAD(P)H dehydrogenase (quinone) Belongs to the NmrA-type oxidoreductase family%3B KEGG: sxi:SXIM_50260 NAD(P)H dehydrogenase (quinone) gene gene4439 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04440 BL14DL4_04441 BL14DL4_04441 BL14DL4_04441 4285266 4285571 - hypothetical protein gene gene4440 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04441 BL14DL4_04442 BL14DL4_04442 BL14DL4_04442 4285729 4286184 + uncharacterized protein Belongs to the OsmC/Ohr family gene gene4441 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04442 BL14DL4_04443 BL14DL4_04443 BL14DL4_04443 4286181 4286540 - Multidrug resistance protein EbrB Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene4442 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04443 BL14DL4_044430 BL14DL4_044430 BL14DL4_044430 4275743 4276054 + UPF0145 protein Belongs to the UPF0145 family gene gene4429 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_044430 BL14DL4_04444 BL14DL4_04444 BL14DL4_04444 4286554 4286871 - Multidrug resistance protein EbrA Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide%2C acriflavine%2C pyronine Y and safranin O. The efflux is probably coupled to an influx of protons (By similarity)%3B Belongs to the small multidrug resistance (SMR) protein family. EbrA/EbrB (TC 2. A. 7. 1. 6) subfamily gene gene4443 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04444 BL14DL4_04445 BL14DL4_04445 BL14DL4_04445 4287279 4287500 - hypothetical protein gene gene4444 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04445 BL14DL4_04446 BL14DL4_04446 BL14DL4_04446 4287626 4288027 + uncharacterized protein gene gene4445 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04446 BL14DL4_04447 BL14DL4_04447 miaA miaA 4288129 4289073 + tRNA dimethylallyltransferase Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine%2C leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)%3B Belongs to the IPP transferase family%3B KEGG: bli:BL05174 tRNA dimethylallyltransferase gene gene4446 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04447 BL14DL4_04448 BL14DL4_04448 BL14DL4_04448 4289115 4289336 + RNA-binding protein Hfq RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress%2C environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs%3B Belongs to the Hfq family gene gene4447 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04448 BL14DL4_04449 BL14DL4_04449 BL14DL4_04449 4289627 4289839 + uncharacterized protein gene gene4448 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04449 BL14DL4_04450 BL14DL4_04450 BL14DL4_04450 4290086 4290484 + Protein NrdI Probably involved in ribonucleotide reductase function%3B Belongs to the NrdI family gene gene4449 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04450 BL14DL4_04451 BL14DL4_04451 BL14DL4_04451 4290441 4292543 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase large chain family%3B KEGG: bsu:BSU17380 ribonucleoside-diphosphate reductase alpha chain gene gene4450 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04451 BL14DL4_04452 BL14DL4_04452 BL14DL4_04452 4292531 4293541 + Ribonucleoside-diphosphate reductase Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)%3B Belongs to the ribonucleoside diphosphate reductase small chain family%3B KEGG: bsu:BSU17390 ribonucleoside-diphosphate reductase beta chain gene gene4451 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04452 BL14DL4_04453 BL14DL4_04453 BL14DL4_04453 4293655 4294272 + uncharacterized protein gene gene4452 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04453 BL14DL4_04454 BL14DL4_04454 BL14DL4_04454 4294290 4295072 - 7%2C8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene5'-phosphate synthase KEGG: pya:PYCH_12000 7%2C8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase gene gene4453 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04454 BL14DL4_04455 BL14DL4_04455 BL14DL4_04455 4295286 4295717 + Iron-sulfur cluster assembly scaffold protein IscU A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity)%3B Belongs to the NifU family gene gene4454 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04455 BL14DL4_04456 BL14DL4_04456 BL14DL4_04456 4295844 4296275 + Peroxide-responsive repressor PerR Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor (By similarity)%3B Belongs to the Fur family gene gene4455 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04456 BL14DL4_04457 BL14DL4_04457 BL14DL4_04457 4296281 4296985 + HTH-type transcriptional regulator McbR Important for biofilm formation. Represses expression of McbA by binding to its promoter region%2C which prevents colanic acid overproduction and mucoidy%3B Contains 1 HTH gntR-type DNA-binding domain gene gene4456 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04457 BL14DL4_04458 BL14DL4_04458 BL14DL4_04458 4296993 4297961 + putative 42.1 kDa protein in intracellular alkaline protease 3'region gene gene4457 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04458 BL14DL4_04459 BL14DL4_04459 BL14DL4_04459 4298016 4298777 - N-acetylmuramoyl-L-alanine amidase Autolysins are involved in some important biological processes such as cell separation%2C cell-wall turnover%2C competence for genetic transformation%2C formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B. subtilis. Its main function is to lyze the mother cell wall peptidoglycan%2C playing a role during sporulation%3B Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family%3B Contains 1 SPOR domain%3B KEGG: bsu:BSU17410 N-acetylmuramoyl-L-alanine amidase gene gene4458 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04459 BL14DL4_04460 BL14DL4_04460 BL14DL4_04460 4299310 4299792 - hypothetical protein gene gene4459 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04460 BL14DL4_04461 BL14DL4_04461 BL14DL4_04461 4299815 4300267 - hypothetical protein gene gene4460 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04461 BL14DL4_04462 BL14DL4_04462 BL14DL4_04462 4300367 4300612 - hypothetical protein gene gene4461 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04462 BL14DL4_04463 BL14DL4_04463 BL14DL4_04463 4300795 4300998 + Repressor rok gene gene4462 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04463 BL14DL4_04464 BL14DL4_04464 BL14DL4_04464 4301212 4301835 + HTH-type transcriptional repressor KstR2 Controls the expression of a small regulon that may play a role in the utilization of cholesterol%3B Contains 1 HTH tetR-type DNA-binding domain gene gene4463 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04464 BL14DL4_04465 BL14DL4_04465 BL14DL4_04465 4301838 4302224 + hypothetical protein gene gene4464 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04465 BL14DL4_04466 BL14DL4_04466 BL14DL4_04466 4302257 4303606 + Cytosine permease Required for cytosine transport into the cell. Belongs to the purine-cytosine permease (2. A. 39) family gene gene4465 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04466 BL14DL4_04467 BL14DL4_04467 BL14DL4_04467 4303631 4305736 + N-methylhydantoinase (ATP-hydrolyzing) Catalyzes the carboxylation of acetophenone to form 3- oxo-3-phenylpropanoate (benzoylacetate) in the anaerobic catabolism of ethylbenzene. Also carboxylates propiophenone at the same rate and 4-acetyl-pyridine at lower rates%3B Belongs to the oxoprolinase family%3B KEGG: bld:BLi01982 N-methylhydantoinase A gene gene4466 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04467 BL14DL4_04468 BL14DL4_04468 BL14DL4_04468 4305733 4307211 + N-methylhydantoinase (ATP-hydrolyzing) Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Acts in the glutathione degradation pathway%3B Belongs to the oxoprolinase family%3B KEGG: baci:B1NLA3E_09215 N-methylhydantoinase B gene gene4467 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04468 BL14DL4_04469 BL14DL4_04469 BL14DL4_04469 4307208 4308947 + N-methylhydantoinase (ATP-hydrolyzing) Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the oxoprolinase family%3B KEGG: bli:BL00460 N-methylhydantoinase B gene gene4468 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04469 BL14DL4_04470 BL14DL4_04470 BL14DL4_04470 4309120 4309554 + hypothetical protein gene gene4469 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04470 BL14DL4_04471 BL14DL4_04471 BL14DL4_04471 4309863 4310033 + hypothetical protein gene gene4470 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04471 BL14DL4_04472 BL14DL4_04472 BL14DL4_04472 4310625 4310966 + hypothetical protein gene gene4471 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04472 BL14DL4_04473 BL14DL4_04473 BL14DL4_04473 4311485 4311676 + hypothetical protein gene gene4472 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04473 BL14DL4_04474 BL14DL4_04474 BL14DL4_04474 4312246 4312944 + hypothetical protein gene gene4473 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04474 BL14DL4_04475 BL14DL4_04475 BL14DL4_04475 4313359 4313949 + Stage V sporulation protein Belongs to the cbxX/cfxQ family gene gene4474 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04475 BL14DL4_04476 BL14DL4_04476 BL14DL4_04476 4313946 4314344 + hypothetical protein gene gene4475 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04476 BL14DL4_04477 BL14DL4_04477 BL14DL4_04477 4314613 4315602 + hypothetical protein gene gene4476 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04477 BL14DL4_04478 BL14DL4_04478 BL14DL4_04478 4315625 4316179 + uncharacterized protein gene gene4477 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04478 BL14DL4_04479 BL14DL4_04479 BL14DL4_04479 4316338 4318293 + Ribonuclease YxiD Toxic component of a toxin-antitoxin (TA) module. The C- terminus (residues 409-569) has RNase activity%2C and inhibits growth upon expression in E. coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD%2C but not by antitoxins specific to other toxins with the LXG domain%3B Contains 1 LXG domain gene gene4478 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04479 BL14DL4_04480 BL14DL4_04480 BL14DL4_04480 4318308 4318730 + Antitoxin YobK Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YobL%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene4479 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04480 BL14DL4_04481 BL14DL4_04481 BL14DL4_04481 4318771 4319229 + Antitoxin YobK Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the RNase activity of cognate toxin YobL%2C as well as its ability to inhibit growth upon expression in E. coli. Does not have antitoxin activity on other toxins with the LXG toxin domain gene gene4480 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04481 BL14DL4_04482 BL14DL4_04482 BL14DL4_04482 4319515 4319997 + Repressor rok gene gene4481 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04482 BL14DL4_04483 BL14DL4_04483 BL14DL4_04483 4320067 4320420 + hypothetical protein gene gene4482 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04483 BL14DL4_04484 BL14DL4_04484 BL14DL4_04484 4320562 4321821 + putative MFS-type transporter YvqJ Belongs to the major facilitator superfamily gene gene4483 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04484 BL14DL4_04485 BL14DL4_04485 BL14DL4_04485 4321932 4323038 + Response regulator aspartate phosphatase Belongs to the RAP family%3B Contains 5 TPR repeats%3B KEGG: bso:BSNT_02017 response regulator aspartate phosphatase K%3B Acting on ester bonds gene gene4484 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04485 BL14DL4_04486 BL14DL4_04486 BL14DL4_04486 4323035 4323163 + hypothetical protein gene gene4485 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04486 BL14DL4_04487 BL14DL4_04487 BL14DL4_04487 4323884 4324183 - hypothetical protein gene gene4486 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04487 BL14DL4_04488 BL14DL4_04488 BL14DL4_04488 4324202 4324456 - hypothetical protein gene gene4487 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04488 BL14DL4_04489 BL14DL4_04489 BL14DL4_04489 4324475 4324861 - hypothetical protein gene gene4488 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04489 BL14DL4_04490 BL14DL4_04490 BL14DL4_04490 4324993 4326081 - N-acetylmuramoyl-L-alanine amidase Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family%3B KEGG: bli:BL01582 N-acetylmuramoyl-L-alanine amidase gene gene4489 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04490 BL14DL4_04491 BL14DL4_04491 BL14DL4_04491 4326237 4328141 - hypothetical protein gene gene4490 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04491 BL14DL4_04492 BL14DL4_04492 BL14DL4_04492 4328157 4328954 - SPBc2 prophage-derived uncharacterized protein YomF gene gene4491 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04492 BL14DL4_04493 BL14DL4_04493 BL14DL4_04493 4328970 4331609 - SPBc2 prophage-derived uncharacterized protein YomG Contains 1 fibronectin type-III domain gene gene4492 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04493 BL14DL4_04494 BL14DL4_04494 BL14DL4_04494 4331613 4332119 - SPBc2 prophage-derived uncharacterized protein YomH gene gene4493 http://www.ncbi.nlm.nih.gov/gene/?term=BL14DL4_04494